Damage identification of beam structures using free response shapes obtained by use of a continuously scanning laser Doppler vibrometer system

NASA Astrophysics Data System (ADS)

Xu, Y. F.; Chen, Da-Ming; Zhu, W. D.

2017-08-01

Spatially dense operating deflection shapes and mode shapes can be rapidly obtained by use of a continuously scanning laser Doppler vibrometer (CSLDV) system, which sweeps its laser spot over a vibrating structure surface. This paper introduces a new type of vibration shapes called a free response shape (FRS) that can be obtained by use of a CSLDV system, and a new damage identification methodology using FRSs is developed for beam structures. An analytical expression of FRSs of a damped beam structure is derived, and FRSs from the analytical expression compare well with those from a finite element model. In the damage identification methodology, a free-response damage index (FRDI) is proposed, and damage regions can be identified near neighborhoods with consistently high values of FRDIs associated with different modes; an auxiliary FRDI is defined to assist identification of the neighborhoods. A FRDI associated with a mode consists of differences between curvatures of FRSs associated with the mode in a number of half-scan periods of a CSLDV system and those from polynomials that fit the FRSs with properly determined orders. A convergence index is proposed to determine the proper order of a polynomial fit. One advantage of the methodology is that the FRDI does not require any baseline information of an undamaged beam structure, if it is geometrically smooth and made of materials that have no stiffness and mass discontinuities. Another advantage is that FRDIs associated with multiple modes can be obtained using free response of a beam structure measured by a CSLDV system in one scan. The number of half-scan periods for calculation of the FRDI associated with a mode can be determined by use of the short-time Fourier transform. The proposed methodology was numerically and experimentally applied to identify damage in beam structures; effects of the scan frequency of a CSLDV system on qualities of obtained FRSs were experimentally investigated.

Development of the compact proton beam therapy system dedicated to spot scanning with real-time tumor-tracking technology

NASA Astrophysics Data System (ADS)

Umezawa, Masumi; Fujimoto, Rintaro; Umekawa, Tooru; Fujii, Yuusuke; Takayanagi, Taisuke; Ebina, Futaro; Aoki, Takamichi; Nagamine, Yoshihiko; Matsuda, Koji; Hiramoto, Kazuo; Matsuura, Taeko; Miyamoto, Naoki; Nihongi, Hideaki; Umegaki, Kikuo; Shirato, Hiroki

2013-04-01

Hokkaido University and Hitachi Ltd. have started joint development of the Gated Spot Scanning Proton Therapy with Real-Time Tumor-Tracking System by integrating real-time tumor tracking technology (RTRT) and the proton therapy system dedicated to discrete spot scanning techniques under the "Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program)". In this development, we have designed the synchrotron-based accelerator system by using the advantages of the spot scanning technique in order to realize a more compact and lower cost proton therapy system than the conventional system. In the gated irradiation, we have focused on the issues to maximize irradiation efficiency and minimize the dose errors caused by organ motion. In order to understand the interplay effect between scanning beam delivery and target motion, we conducted a simulation study. The newly designed system consists of the synchrotron, beam transport system, one compact rotating gantry treatment room with robotic couch, and one experimental room for future research. To improve the irradiation efficiency, the new control function which enables multiple gated irradiations per synchrotron cycle has been applied and its efficacy was confirmed by the irradiation time estimation. As for the interplay effect, we confirmed that the selection of a strict gating width and scan direction enables formation of the uniform dose distribution.

Fundamental radiological and geometric performance of two types of proton beam modulated discrete scanning systems.

PubMed

Farr, J B; Dessy, F; De Wilde, O; Bietzer, O; Schönenberg, D

2013-07-01

The purpose of this investigation was to compare and contrast the measured fundamental properties of two new types of modulated proton scanning systems. This provides a basis for clinical expectations based on the scanned beam quality and a benchmark for computational models. Because the relatively small beam and fast scanning gave challenges to the characterization, a secondary purpose was to develop and apply new approaches where necessary to do so. The following performances of the proton scanning systems were investigated: beamlet alignment, static in-air beamlet size and shape, scanned in-air penumbra, scanned fluence map accuracy, geometric alignment of scanning system to isocenter, maximum field size, lateral and longitudinal field uniformity of a 1 l cubic uniform field, output stability over time, gantry angle invariance, monitoring system linearity, and reproducibility. A range of detectors was used: film, ionization chambers, lateral multielement and longitudinal multilayer ionization chambers, and a scintillation screen combined with a digital video camera. Characterization of the scanned fluence maps was performed with a software analysis tool. The resulting measurements and analysis indicated that the two types of delivery systems performed within specification for those aspects investigated. The significant differences were observed between the two types of scanning systems where one type exhibits a smaller spot size and associated penumbra than the other. The differential is minimum at maximum energy and increases inversely with decreasing energy. Additionally, the large spot system showed an increase in dose precision to a static target with layer rescanning whereas the small spot system did not. The measured results from the two types of modulated scanning types of system were consistent with their designs under the conditions tested. The most significant difference between the types of system was their proton spot size and associated resolution, factors of magnetic optics, and vacuum length. The need and benefit of mutielement detectors and high-resolution sensors was also shown. The use of a fluence map analytical software tool was particularly effective in characterizing the dynamic proton energy-layer scanning.

Real-time continuous-wave terahertz line scanner based on a compact 1 × 240 InGaAs Schottky barrier diode array detector.

PubMed

Han, Sang-Pil; Ko, Hyunsung; Kim, Namje; Lee, Won-Hui; Moon, Kiwon; Lee, Il-Min; Lee, Eui Su; Lee, Dong Hun; Lee, Wangjoo; Han, Seong-Tae; Choi, Sung-Wook; Park, Kyung Hyun

2014-11-17

We demonstrate real-time continuous-wave terahertz (THz) line-scanned imaging based on a 1 × 240 InGaAs Schottky barrier diode (SBD) array detector with a scan velocity of 25 cm/s, a scan line length of 12 cm, and a pixel size of 0.5 × 0.5 mm². Foreign substances, such as a paper clip with a spatial resolution of approximately 1 mm that is hidden under a cracker, are clearly detected by this THz line-scanning system. The system consists of the SBD array detector, a 200-GHz gyrotron source, a conveyor system, and several optical components such as a high-density polyethylene cylindrical lens, metal cylindrical mirror, and THz wire-grid polarizer. Using the THz polarizer, the signal-to-noise ratio of the SBD array detector improves because the quality of the source beam is enhanced.

Virtobot--a multi-functional robotic system for 3D surface scanning and automatic post mortem biopsy.

PubMed

Ebert, Lars Christian; Ptacek, Wolfgang; Naether, Silvio; Fürst, Martin; Ross, Steffen; Buck, Ursula; Weber, Stefan; Thali, Michael

2010-03-01

The Virtopsy project, a multi-disciplinary project that involves forensic science, diagnostic imaging, computer science, automation technology, telematics and biomechanics, aims to develop new techniques to improve the outcome of forensic investigations. This paper presents a new approach in the field of minimally invasive virtual autopsy for a versatile robotic system that is able to perform three-dimensional (3D) surface scans as well as post mortem image-guided soft tissue biopsies. The system consists of an industrial six-axis robot with additional extensions (i.e. a linear axis to increase working space, a tool-changing system and a dedicated safety system), a multi-slice CT scanner with equipment for angiography, a digital photogrammetry and 3D optical surface-scanning system, a 3D tracking system, and a biopsy end effector for automatic needle placement. A wax phantom was developed for biopsy accuracy tests. Surface scanning times were significantly reduced (scanning times cut in half, calibration three times faster). The biopsy module worked with an accuracy of 3.2 mm. Using the Virtobot, the surface-scanning procedure could be standardized and accelerated. The biopsy module is accurate enough for use in biopsies in a forensic setting. The Virtobot can be utilized for several independent tasks in the field of forensic medicine, and is sufficiently versatile to be adapted to different tasks in the future. (c) 2009 John Wiley & Sons, Ltd.

Slit-scanning differential x-ray phase-contrast mammography: proof-of-concept experimental studies.

PubMed

Koehler, Thomas; Daerr, Heiner; Martens, Gerhard; Kuhn, Norbert; Löscher, Stefan; van Stevendaal, Udo; Roessl, Ewald

2015-04-01

The purpose of this work is to investigate the feasibility of grating-based, differential phase-contrast, full-field digital mammography (FFDM) in terms of the requirements for field-of-view (FOV), mechanical stability, and scan time. A rigid, actuator-free Talbot interferometric unit was designed and integrated into a state-of-the-art x-ray slit-scanning mammography system, namely, the Philips MicroDose L30 FFDM system. A dedicated phase-acquisition and phase retrieval method was developed and implemented that exploits the redundancy of the data acquisition inherent to the slit-scanning approach to image generation of the system. No modifications to the scan arm motion control were implemented. The authors achieve a FOV of 160 × 196 mm consisting of two disjoint areas measuring 77 × 196 mm with a gap of 6 mm between them. Typical scanning times vary between 10 and 15 s and dose levels are lower than typical FFDM doses for conventional scans with identical acquisition parameters due to the presence of the source-grating G0. Only minor to moderate artifacts are observed in the three reconstructed images, indicating that mechanical vibrations induced by other system components do not prevent the use of the platform for phase contrast imaging. To the best of our knowledge, this is the first attempt to integrate x-ray gratings hardware into a clinical mammography unit. The results demonstrate that a scanning differential phase contrast FFDM system that meets the requirements of FOV, stability, scan time, and dose can be build.

Development of 3-D Ice Accretion Measurement Method

NASA Technical Reports Server (NTRS)

Lee, Sam; Broeren, Andy P.; Addy, Harold E., Jr.; Sills, Robert; Pifer, Ellen M.

2012-01-01

A research plan is currently being implemented by NASA to develop and validate the use of a commercial laser scanner to record and archive fully three-dimensional (3-D) ice shapes from an icing wind tunnel. The plan focused specifically upon measuring ice accreted in the NASA Icing Research Tunnel (IRT). The plan was divided into two phases. The first phase was the identification and selection of the laser scanning system and the post-processing software to purchase and develop further. The second phase was the implementation and validation of the selected system through a series of icing and aerodynamic tests. Phase I of the research plan has been completed. It consisted of evaluating several scanning hardware and software systems against an established selection criteria through demonstrations in the IRT. The results of Phase I showed that all of the scanning systems that were evaluated were equally capable of scanning ice shapes. The factors that differentiated the scanners were ease of use and the ability to operate in a wide range of IRT environmental conditions.

Five-dimensional ultrasound system for soft tissue visualization.

PubMed

Deshmukh, Nishikant P; Caban, Jesus J; Taylor, Russell H; Hager, Gregory D; Boctor, Emad M

2015-12-01

A five-dimensional ultrasound (US) system is proposed as a real-time pipeline involving fusion of 3D B-mode data with the 3D ultrasound elastography (USE) data as well as visualization of these fused data and a real-time update capability over time for each consecutive scan. 3D B-mode data assist in visualizing the anatomy of the target organ, and 3D elastography data adds strain information. We investigate the feasibility of such a system and show that an end-to-end real-time system, from acquisition to visualization, can be developed. We present a system that consists of (a) a real-time 3D elastography algorithm based on a normalized cross-correlation (NCC) computation on a GPU; (b) real-time 3D B-mode acquisition and network transfer; (c) scan conversion of 3D elastography and B-mode volumes (if acquired by 4D wobbler probe); and (d) visualization software that fuses, visualizes, and updates 3D B-mode and 3D elastography data in real time. We achieved a speed improvement of 4.45-fold for the threaded version of the NCC-based 3D USE versus the non-threaded version. The maximum speed was 79 volumes/s for 3D scan conversion. In a phantom, we validated the dimensions of a 2.2-cm-diameter sphere scan-converted to B-mode volume. Also, we validated the 5D US system visualization transfer function and detected 1- and 2-cm spherical objects (phantom lesion). Finally, we applied the system to a phantom consisting of three lesions to delineate the lesions from the surrounding background regions of the phantom. A 5D US system is achievable with real-time performance. We can distinguish between hard and soft areas in a phantom using the transfer functions.

An interchangeable scanning Hall probe/scanning SQUID microscope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tang, Chiu-Chun; Lin, Hui-Ting; Wu, Sing-Lin

2014-08-15

We have constructed a scanning probe microscope for magnetic imaging, which can function as a scanning Hall probe microscope (SHPM) and as a scanning SQUID microscope (SSM). The scanning scheme, applicable to SHPM and SSM, consists of a mechanical positioning (sub) micron-XY stage and a flexible direct contact to the sample without a feedback control system for the Z-axis. With the interchangeable capability of operating two distinct scanning modes, our microscope can incorporate the advantageous functionalities of the SHPM and SSM with large scan range up to millimeter, high spatial resolution (⩽4 μm), and high field sensitivity in a widemore » range of temperature (4.2 K-300 K) and magnetic field (10{sup −7} T-1 T). To demonstrate the capabilities of the system, we present magnetic images scanned with SHPM and SSM, including a RbFeB magnet and a nickel grid pattern at room temperature, surface magnetic domain structures of a La{sub 2/3}Ca{sub 1/3}MnO{sub 3} thin film at 77 K, and superconducting vortices in a striped niobium film at 4.2 K.« less

Table screen 360-degree holographic display using circular viewing-zone scanning.

PubMed

Inoue, Tatsuaki; Takaki, Yasuhiro

2015-03-09

A table screen 360-degree holographic display is proposed, with an increased screen size, having an expanded viewing zone over all horizontal directions around the table screen. It consists of a microelectromechanical systems spatial light modulator (MEMS SLM), a magnifying imaging system, and a rotating screen. The MEMS SLM generates hologram patterns at a high frame rate, the magnifying imaging system increases the screen of the MEMS SLM, and the reduced viewing zones are scanned circularly by the rotating screen. The viewing zones are localized to practically realize wavefront reconstruction. An experimental system has been constructed. The generation of 360-degree three-dimensional (3D) images was achieved by scanning 800 reduced and localized viewing zones circularly. The table screen had a diameter of 100 mm, and the frame rate of 3D image generation was 28.4 Hz.

Miniaturized high throughput detection system for capillary array electrophoresis on chip with integrated light emitting diode array as addressed ring-shaped light source.

PubMed

Ren, Kangning; Liang, Qionglin; Mu, Xuan; Luo, Guoan; Wang, Yiming

2009-03-07

A novel miniaturized, portable fluorescence detection system for capillary array electrophoresis (CAE) on a microfluidic chip was developed, consisting of a scanning light-emitting diode (LED) light source and a single point photoelectric sensor. Without charge coupled detector (CCD), lens, fibers and moving parts, the system was extremely simplified. Pulsed driving of the LED significantly increased the sensitivity, and greatly reduced the power consumption and photobleaching effect. The highly integrated system was robust and easy to use. All the advantages realized the concept of a portable micro-total analysis system (micro-TAS), which could work on a single universal serial bus (USB) port. Compared with traditional CAE detecting systems, the current system could scan the radial capillary array with high scanning rate. An 8-channel CAE of fluorescein isothiocyanate (FITC) labeled arginine (Arg) on chip was demonstrated with this system, resulting in a limit of detection (LOD) of 640 amol.

Point Cloud Analysis for Uav-Borne Laser Scanning with Horizontally and Vertically Oriented Line Scanners - Concept and First Results

NASA Astrophysics Data System (ADS)

Weinmann, M.; Müller, M. S.; Hillemann, M.; Reydel, N.; Hinz, S.; Jutzi, B.

2017-08-01

In this paper, we focus on UAV-borne laser scanning with the objective of densely sampling object surfaces in the local surrounding of the UAV. In this regard, using a line scanner which scans along the vertical direction and perpendicular to the flight direction results in a point cloud with low point density if the UAV moves fast. Using a line scanner which scans along the horizontal direction only delivers data corresponding to the altitude of the UAV and thus a low scene coverage. For these reasons, we present a concept and a system for UAV-borne laser scanning using multiple line scanners. Our system consists of a quadcopter equipped with horizontally and vertically oriented line scanners. We demonstrate the capabilities of our system by presenting first results obtained for a flight within an outdoor scene. Thereby, we use a downsampling of the original point cloud and different neighborhood types to extract fundamental geometric features which in turn can be used for scene interpretation with respect to linear, planar or volumetric structures.

First Results of the Land Atmosphere Feedback Experiment

NASA Astrophysics Data System (ADS)

Wulfmeyer, V.; Turner, D. D.

2017-12-01

The Land-Atmosphere Feedback Experiment (LAFE) deployed several state-of-the-art scanning lidar and remote sensing systems to the ARM SGP site during August 2017. A novel synergy of remote sensing systems was applied for simultaneous measurements of land-surface fluxes and horizontal and vertical transport processes in the atmospheric boundary layer (ABL). The impact of spatial inhomogeneities of the soil-vegetation continuum on LA feedback was studied using the scanning capability of the instrumentation as well as soil, vegetation, and surface flux measurements. The synergy of remote sensing and in-situ instruments consisted of three components: 1) The SGP water-vapor and temperature Raman lidar, the SGP Doppler lidar, the University of Hohenheim (UHOH) Doppler lidar, and the NCAR water-vapor DIAL to measure mean profiles and gradients of moisture, temperature, and horizontal wind. Due to their high vertical and temporal resolutions, also profiles of higher-order turbulent moments in the water vapor and wind fields as well as of profiles of the latent heat flux, the sensible heat flux, TKE, and momentum flux were observed. 2) A novel scanning lidar system synergy consisting of the NOAA High-Resolution Doppler lidar, the UHOH water-vapor differential absorption lidar, and the UHOH temperature rotational Raman lidar. These systems performed coordinated range-height indicator (RHI) scans from just above the canopy level to the lower troposphere including the interfacial layer at the ABL top. This component was augmented by three energy balance closure towers of NOAA and one EBC station of UHOH. 3) The University of Wisconsin SPARC and the University of Oklahoma CLAMPS systems operating two vertically pointing atmospheric emitted radiance interferometers and two Doppler lidar systems scanning cross track to the central RHI for determining the surface friction velocity and the horizontal variability of temperature, moisture, and wind. NOAA ARL also provided UAS and aircraft measurements (Navajo Piper) in accordance with the surface scans. Thus, both the variability of surface fluxes and CBL dynamics and thermodynamics over the SGP site was studied for the first time. This is essential for advanced observation and understanding of LA feedback. First results are presented at the conference.

A scanned focused ultrasound device for hyperthermia: numerical simulation and prototype implementation

NASA Astrophysics Data System (ADS)

Meaney, Paul M.; Raynolds, Timothy; Geimer, Shireen D.; Potwin, Lincoln; Paulsen, Keith D.

2004-07-01

We are developing a scanned focused ultrasound system for hyperthermia treatment of breast cancer. Focused ultrasound has significant potential as a therapy delivery device because it can focus sufficient heating energy below the skin surface with minimal damage to intervening tissue. However, as a practical therapy system, the focal zone is generally quite small and requires either electronic (in the case of a phased array system) or mechanical steering (for a fixed bowl transducer) to cover a therapeutically useful area. We have devised a simple automated steering system consisting of a focused bowl transducer supported by three vertically movable rods which are connected to computer controlled linear actuators. This scheme is particularly attractive for breast cancer hyperthermia where the support rods can be fed through the base of a liquid coupling tank to treat tumors within the breast while coupled to our noninvasive microwave thermal imaging system. A MATLAB routine has been developed for controlling the rod motion such that the beam focal point scans a horizontal spiral and the subsequent heating zone is cylindrical. In coordination with this effort, a 3D finite element thermal model has been developed to evaluate the temperature distributions from the scanned focused heating. In this way, scanning protocols can be optimized to deliver the most uniform temperature rise to the desired location.

A novel scanning system using an industrial robot and the workspace measurement and positioning system

NASA Astrophysics Data System (ADS)

Zhao, Ziyue; Zhu, Jigui; Yang, Linghui; Lin, Jiarui

2015-10-01

The present scanning system consists of an industrial robot and a line-structured laser sensor which uses the industrial robot as a position instrument to guarantee the accuracy. However, the absolute accuracy of an industrial robot is relatively poor compared with the good repeatability in the manufacturing industry. This paper proposes a novel method using the workspace measurement and positioning system (wMPS) to remedy the lack of accuracy of the industrial robot. In order to guarantee the positioning accuracy of the system, the wMPS which is a laser-based measurement technology designed for large-volume metrology applications is brought in. Benefitting from the wMPS, this system can measure different cell-areas by the line-structured laser sensor and fuse the measurement data of different cell-areas by using the wMPS accurately. The system calibration which is the procedure to acquire and optimize the structure parameters of the scanning system is also stated in detail in this paper. In order to verify the feasibility of the system for scanning the large free-form surface, an experiment is designed to scan the internal surface of the door of a car-body in white. The final results show that the measurement data of the whole measuring areas have been jointed perfectly and there is no mismatch in the figure especially in the hole measuring areas. This experiment has verified the rationality of the system scheme, the correctness and effectiveness of the relevant methods.

Implementation and Validation of 3-D Ice Accretion Measurement Methodology

NASA Technical Reports Server (NTRS)

Lee, Sam; Broeren, Andy P.; Kreeger, Richard E.; Potapczuk, Mark; Utt, Lloyd

2014-01-01

A research program has been implemented to develop and validate the use of a commercial 3-D laser scanning system to record ice accretion geometry in the NASA Icing Research Tunnel. A main component of the program was the geometric assessment of the 3- D laser scanning system on a 2-D (straight wing) and a 3-D (swept wing) airfoil geometries. This exercise consisted of comparison of scanned ice accretion to castings of the same ice accretion. The scan data were also used to create rapid prototype artificial ice shapes that were scanned and compared to the original ice accretion. The results from geometric comparisons on the straight wing showed that the ice shape models generated through the scan/rapid prototype process compared reasonably well with the cast shapes. Similar results were obtained with the geometric comparisons on the swept wing. It was difficult to precisely compare the scans of the cast shapes to the original ice accretion scans because the cast shapes appear to have shrunk during the mold/casting process by as much as 0.10-inch. However the comparison of the local ice-shape features were possible and produced better results. The rapid prototype manufacturing process was shown to reproduce the original ice accretion scan normally within 0.01-inch.

IMRT verification using a radiochromic/optical-CT dosimetry system

NASA Astrophysics Data System (ADS)

Oldham, Mark; Guo, Pengyi; Gluckman, Gary; Adamovics, John

2006-12-01

This work represents our first experiences relating to IMRT verification using a relatively new 3D dosimetry system consisting of a PRESAGETM dosimeter (Heuris Inc, Pharma LLC) and an optical-CT scanning system (OCTOPUSTM TM MGS Inc). This work builds in a step-wise manner on prior work in our lab.

Miniature Fourier transform spectrometer with a dual closed-loop controlled electrothermal micromirror.

PubMed

Han, Fengtian; Wang, Wei; Zhang, Xiaoyang; Xie, Huikai

2016-10-03

A large piston-displacement electrothermal micromirror with closed-loop control of both piston scan and tilting of the mirror plate is demonstrated for use in a miniature Fourier transform spectrometer. Constant scan velocity in an ultra large piston scan range has been demonstrated by the proposed closed-loop piston control scheme which can be easily implemented without considerably increasing system complexity. The experimental results show that the usable linear scan range generated by the micromirror has been extended up to 505 μm. The measured spectral resolution in a compact spectrometer reaches 20 cm^-1, or 0.57 nm at 532 nm wavelength. Compared to other presented systems, this microspectrometer will benefit from the closed-loop thermal actuator approach utilizing both the piston servo and tilt control to provide more consistent spectral response, improved spectral resolution and enhanced robustness to disturbances.

Airline pilot scan patterns during simulated ILS approaches

NASA Technical Reports Server (NTRS)

Spady, A. A., Jr.

1978-01-01

A series of instrument landing system approaches were conducted using seven airline-rated Boeing 737 pilots in a Federal Aviation Administration qualified simulator. The test matrix included both manual and coupled approaches with and without atmospheric turbulence in Category II visibility conditions. A nonintrusive oculometer system was used to track the pilot eye-point-of-regard throughout the approach. The results indicate that, in general, the pilots use different scan techniques for the manual and coupled conditions and that the introduction of atmospheric turbulence does not greatly affect the scan behavior in either case. The pilots consistently ranked the instruments in terms of most used to least used. The ranking obtained from the oculometer data agrees with the pilot ranking for the flight director and airspeed, the most important instruments. However, the pilots apparently ranked the other instruments in terms of their concern for information rather than according to their actual scanning behavior.

Suomi-NPP Mission On-Orbit Experience with Toroid Ball Bearing Retainers Under Unidirectional and Reversing Motion

NASA Technical Reports Server (NTRS)

Bruegman, Otto; Thakore, Kamal; Loewenthal, Stu; Cymerman, John

2016-01-01

The Advanced Technology Microwave Sounder (ATMS) instrument scan system on the Suomi National Polar-orbiting Partnership (SNPP) spacecraft has experienced several randomly occurring increased torque 'events' since its on-orbit activation in November 2011. Based on a review of on-orbit telemetry data and data gathered from scan mechanism bearing life testing on the ground, the conclusion was drawn that some degradation of Teflon toroid ball retainers was occurring in the instrument Scan Drive Mechanism. A life extension program was developed and executed on-orbit with very good results to date. The life extension program consisted of reversing the mechanism for a limited number of consecutive scans every day.

Development of reflective optical systems for XUV projection lithography

NASA Astrophysics Data System (ADS)

Viswanathan, V. K.; Newnam, B. E.

We describe two full-field reflective reduction systems (1 and 6.25 sq cm image area) and one scanning system (25 mm x scan length image size) that meet the performance requirements for 0.1-micron resolution projection lithography using extreme-ultraviolet (XUV) wavelengths from 10 to 15 nm. These systems consist of two centered, symmetric, annular aspheric mirrors with 35 to 40 percent central obscuration, providing a reduction ratio of 3.3 x. Outstanding features include the remarkably low distortion (less than or = 10 nm) over the entire image field and the comparatively liberal tolerances on the mirror radii and alignment. While optimized annular illumination can improve the performance, the required performance can be met with full illumination, thereby allowing a simpler system design.

Lasers for Training Devices.

ERIC Educational Resources Information Center

Fuller, C. A.

A breadboard model of a laser display system is described in detail and its operating procedure is outlined. The system consists of: a Model 52 argon krypton ion laser and power supply; an optical breadboard comprising a pocket cell light modulator, a galvonmeter beam deflector for vertical scanning, a unique multiple reflection beam steerer for…

Ultrasonic characterization of damage in a simulated CF-18 composite structure

NASA Astrophysics Data System (ADS)

McRae, K. I.; Finlayson, R. D.; Sturrock, W. R.; Liesch, D. S.

1993-02-01

A simulated CF-18 aircraft door component was constructed and subjected to treatment during manufacturing with the object of inducing damage in the composite material in a known and well-defined manner. The simulated component was then sent to participants in a nondestructive evaluation study. Results are reported for tests conducted with a scanning apparatus and data acquisition system which consisted of three components: ultrasonic transducer and scanner comprising a two-axis scanning frame to which a modified commercial transducer was attached; an acquisition system for ultrasonic data known as Signal Processing Ultrasonic Device (SPUD); and a data analysis and display system (DETECT/NDE) specifically designed to manipulate large three dimensional ultrasonic data sets. A series of five large-area scans was performed, each scan about 52 cm square. A total of eight regions of interest were identified for a more detailed analysis of the delamination damage, seven detailed scans covering a 13-cm square and one covering a 20.8-cm square. It was often possible to identify the probable source of the damage as that resulting from impact or caused by overloading of fasteners. Flaws of all significant dimensions were located and fully characterized using the ultrasonic procedure.

A spacecraft attitude and articulation control system design for the Comet Halley intercept mission

NASA Technical Reports Server (NTRS)

Key, R. W.

1981-01-01

An attitude and articulation control system design for the Comet Halley 1986 intercept mission is presented. A spacecraft dynamics model consisting of five hinge-connected rigid bodies is used to analyze the spacecraft attitude and articulation control system performance. Inertial and optical information are combined to generate scan platform pointing commands. The comprehensive spacecraft model has been developed into a digital computer simulation program, which provides performance characteristics and insight pertaining to the control and dynamics of a Halley Intercept spacecraft. It is shown that scan platform pointing error has a maximum value of 1.8 milliradians during the four minute closest approach interval. It is also shown that the jitter or scan platform pointing rate error would have a maximum value of 2.5 milliradians/second for the nominal 1000 km closest approach distance trajectory and associated environment model.

Mcps-range photon-counting X-ray computed tomography system utilizing an oscillating linear-YAP(Ce) photon detector

NASA Astrophysics Data System (ADS)

Oda, Yasuyuki; Sato, Eiichi; Abudurexiti, Abulajiang; Hagiwara, Osahiko; Osawa, Akihiro; Matsukiyo, Hiroshi; Enomoto, Toshiyuki; Watanabe, Manabu; Kusachi, Shinya; Sugimura, Shigeaki; Endo, Haruyuki; Sato, Shigehiro; Ogawa, Akira; Onagawa, Jun

2011-07-01

High-speed X-ray photon counting is useful for discriminating photon energy, and the counting can be used for constructing an X-ray computed tomography (CT) system. A photon-counting X-ray CT system consists of an X-ray generator, a turntable, an oscillation linear detector, a two-stage controller, a multipixel photon counter (MPPC) module, a 1.0 mm-thick crystal (scintillator) of YAP(Ce) (cerium-doped yttrium aluminum perovskite), a counter card (CC), and a personal computer (PC). Tomography is accomplished by repeating the linear scanning and the rotation of an object, and projection curves of the object are obtained by the linear scanning using the detector consisting of an MPPC module, the YAP(Ce), and a scan stage. The pulses of the event signal from the module are counted by the CC in conjunction with the PC. Because the lower level of the photon energy was roughly determined by a comparator in the module, the average photon energy of the X-ray spectra increased with increase in the lower-level voltage of the comparator at a constant tube voltage. The maximum count rate was approximately 3 Mcps (mega counts per second), and photon-counting CT was carried out.

Identification of damage in plates using full-field measurement with a continuously scanning laser Doppler vibrometer system

NASA Astrophysics Data System (ADS)

Chen, Da-Ming; Xu, Y. F.; Zhu, W. D.

2018-05-01

An effective and reliable damage identification method for plates with a continuously scanning laser Doppler vibrometer (CSLDV) system is proposed. A new constant-speed scan algorithm is proposed to create a two-dimensional (2D) scan trajectory and automatically scan a whole plate surface. Full-field measurement of the plate can be achieved by applying the algorithm to the CSLDV system. Based on the new scan algorithm, the demodulation method is extended from one dimension for beams to two dimensions for plates to obtain a full-field operating deflection shape (ODS) of the plate from velocity response measured by the CSLDV system. The full-field ODS of an associated undamaged plate is obtained by using polynomials with proper orders to fit the corresponding full-field ODS from the demodulation method. A curvature damage index (CDI) using differences between curvatures of ODSs (CODSs) associated with ODSs that are obtained by the demodulation method and the polynomial fit is proposed to identify damage. An auxiliary CDI obtained by averaging CDIs at different excitation frequencies is defined to further assist damage identification. An experiment of an aluminum plate with damage in the form of 10.5% thickness reduction in a damage area of 0.86% of the whole scan area is conducted to investigate the proposed method. Six frequencies close to natural frequencies of the plate and one randomly selected frequency are used as sinusoidal excitation frequencies. Two 2D scan trajectories, i.e., a horizontally moving 2D scan trajectory and a vertically moving 2D scan trajectory, are used to obtain ODSs, CODSs, and CDIs of the plate. The damage is successfully identified near areas with consistently high values of CDIs at different excitation frequencies along the two 2D scan trajectories; the damage area is also identified by auxiliary CDIs.

Structured-Light Based 3d Laser Scanning of Semi-Submerged Structures

NASA Astrophysics Data System (ADS)

van der Lucht, J.; Bleier, M.; Leutert, F.; Schilling, K.; Nüchter, A.

2018-05-01

In this work we look at 3D acquisition of semi-submerged structures with a triangulation based underwater laser scanning system. The motivation is that we want to simultaneously capture data above and below water to create a consistent model without any gaps. The employed structured light scanner consist of a machine vision camera and a green line laser. In order to reconstruct precise surface models of the object it is necessary to model and correct for the refraction of the laser line and camera rays at the water-air boundary. We derive a geometric model for the refraction at the air-water interface and propose a method for correcting the scans. Furthermore, we show how the water surface is directly estimated from sensor data. The approach is verified using scans captured with an industrial manipulator to achieve reproducible scanner trajectories with different incident angles. We show that the proposed method is effective for refractive correction and that it can be applied directly to the raw sensor data without requiring any external markers or targets.

Construction and performance of a dilution-refrigerator based spectroscopic-imaging scanning tunneling microscope.

PubMed

Singh, U R; Enayat, M; White, S C; Wahl, P

2013-01-01

We report on the set-up and performance of a dilution-refrigerator based spectroscopic imaging scanning tunneling microscope. It operates at temperatures below 10 mK and in magnetic fields up to 14T. The system allows for sample transfer and in situ cleavage. We present first-results demonstrating atomic resolution and the multi-gap structure of the superconducting gap of NbSe(2) at base temperature. To determine the energy resolution of our system we have measured a normal metal/vacuum/superconductor tunneling junction consisting of an aluminum tip on a gold sample. Our system allows for continuous measurements at base temperature on time scales of up to ≈170 h.

1.56 Terahertz 2-frames per second standoff imaging

NASA Astrophysics Data System (ADS)

Goyette, Thomas M.; Dickinson, Jason C.; Linden, Kurt J.; Neal, William R.; Joseph, Cecil S.; Gorveatt, William J.; Waldman, Jerry; Giles, Robert; Nixon, William E.

2008-02-01

A Terahertz imaging system intended to demonstrate identification of objects concealed under clothing was designed, assembled, and tested. The system design was based on a 2.5 m standoff distance, with a capability of visualizing a 0.5 m by 0.5 m scene at an image rate of 2 frames per second. The system optical design consisted of a 1.56 THz laser beam, which was raster swept by a dual torsion mirror scanner. The beam was focused onto the scan subject by a stationary 50 cm-diameter focusing mirror. A heterodyne detection technique was used to down convert the backscattered signal. The system demonstrated a 1.5 cm spot resolution. Human subjects were scanned at a frame rate of 2 frames per second. Hidden metal objects were detected under a jacket worn by the human subject. A movie including data and video images was produced in 1.5 minutes scanning a human through 180° of azimuth angle at 0.7° increment.

Thematic mapper critical elements breadboard program

NASA Technical Reports Server (NTRS)

Dale, C. H., Jr.; Engel, J. L.; Harney, E. D.

1976-01-01

A 40.6 cm bidirectional scan mirror assembly, a scan line corrector and a silicon photodiode array with integral preamplifier input stages were designed, fabricated, and tested to demonstrate performance consistent with requirements of the Hughes thematic mapper system. The measured performance met or exceeded the original design goals in all cases with the qualification that well defined and well understood deficiencies in the design of the photodiode array package will require the prescribed corrections before flight use.

Evidence for multiple hydrogen-ion donor systems in rain

Treesearch

Sagar V. Krupa; M. R., Jr. Coscio; F. A. Wood

1976-01-01

An integrated analytical system consisting of combined scanning electron microscopy and x-ray analysis, atomic absorption, colorimetry and coulometry was used to study rain water chemistry. The coulometry facilitated the determination in molarities of strong and non-volatile and volatile weak acids. The pH of individual rains in St. Paul - Minneapolis, Minnesota ranged...

Development of a highly automated system for the remote evaluation of individual tree parameters

Treesearch

Richard Pollock

2000-01-01

A highly-automated procedure for remotely estimating individual tree location, crown diameter, species class, and height has been developed. This procedure will involve the use of a multimodal airborne sensing system that consists of a digital frame camera, a scanning laser rangefinder, and a position and orientation measurement system. Data from the multimodal sensing...

Dynamic deformation inspection of a human arm by using a line-scan imaging system

NASA Astrophysics Data System (ADS)

Hu, Eryi

2009-11-01

A line-scan imaging system is used in the dynamic deformation measurement of a human arm when the muscle is contracting and relaxing. The measurement principle is based on the projection grating profilometry, and the measuring system is consisted of a line-scan CCD camera, a projector, optical lens and a personal computer. The detected human arm is put upon a reference plane, and a sinusoidal grating is projected onto the object surface and reference plane at an incidence angle, respectively. The deformed fringe pattern in the same line of the dynamic detected arm is captured by the line-scan CCD camera with free trigger model, and the deformed fringe pattern is recorded in the personal computer for processing. A fast Fourier transform combining with a filtering and spectrum shifting method is used to extract the phase information caused by the profile of the detected object. Thus, the object surface profile can be obtained following the geometric relationship between the fringe deformation and the object surface height. Furthermore, the deformation procedure can be obtained line by line. Some experimental results are presented to prove the feasibility of the inspection system.

Spotting L3 slice in CT scans using deep convolutional network and transfer learning.

PubMed

Belharbi, Soufiane; Chatelain, Clément; Hérault, Romain; Adam, Sébastien; Thureau, Sébastien; Chastan, Mathieu; Modzelewski, Romain

2017-08-01

In this article, we present a complete automated system for spotting a particular slice in a complete 3D Computed Tomography exam (CT scan). Our approach does not require any assumptions on which part of the patient's body is covered by the scan. It relies on an original machine learning regression approach. Our models are learned using the transfer learning trick by exploiting deep architectures that have been pre-trained on imageNet database, and therefore it requires very little annotation for its training. The whole pipeline consists of three steps: i) conversion of the CT scans into Maximum Intensity Projection (MIP) images, ii) prediction from a Convolutional Neural Network (CNN) applied in a sliding window fashion over the MIP image, and iii) robust analysis of the prediction sequence to predict the height of the desired slice within the whole CT scan. Our approach is applied to the detection of the third lumbar vertebra (L3) slice that has been found to be representative to the whole body composition. Our system is evaluated on a database collected in our clinical center, containing 642 CT scans from different patients. We obtained an average localization error of 1.91±2.69 slices (less than 5 mm) in an average time of less than 2.5 s/CT scan, allowing integration of the proposed system into daily clinical routines. Copyright © 2017 Elsevier Ltd. All rights reserved.

A flexible system to capture sample vials in a storage box - the box vial scanner.

PubMed

Nowakowski, Steven E; Kressin, Kenneth R; Deick, Steven D

2009-01-01

Tracking sample vials in a research environment is a critical task and doing so efficiently can have a large impact on productivity, especially in high volume laboratories. There are several challenges to automating the capture process, including the variety of containers used to store samples. We developed a fast and robust system to capture the location of sample vials being placed in storage that allows the laboratories the flexibility to use sample containers of varying dimensions. With a single scan, this device captures the box identifier, the vial identifier and the location of each vial within a freezer storage box. The sample vials are tracked through a barcode label affixed to the cap while the boxes are tracked by a barcode label on the side of the box. Scanning units are placed at the point of use and forward data to a sever application for processing the scanned data. Scanning units consist of an industrial barcode reader mounted in a fixture positioning the box for scanning and providing lighting during the scan. The server application transforms the scan data into a list of storage locations holding vial identifiers. The list is then transferred to the laboratory database. The box vial scanner captures the IDs and location information for an entire box of sample vials into the laboratory database in a single scan. The system accommodates a wide variety of vials sizes by inserting risers under the sample box and a variety of storage box layouts are supported via the processing algorithm on the server.

Spatially scanned two-color mid-infrared interferometer for FTU

NASA Astrophysics Data System (ADS)

Canton, A.; Innocente, P.; Martini, S.; Tasinato, L.; Tudisco, O.

2001-01-01

The design of a scanning beam two-color mid-infrared (MIR) interferometer is presented. The diagnostic is being developed for the Frascati Tokamak Upgrade (FTU) which calls for a new interferometer to perform detailed study of advanced confinement regimes in D-shaped plasmas. After performing a feasibility study and a prototype test, we designed a scanning interferometer based on a resonant tilting mirror providing 40 chords of ≈1 cm diameter and a full profile every 62 μs. Such a high number of chords is obtained with a very simple optical scheme, resulting in a system which is compact, low cost, and easy to align. An important feature of the interferometer is its higher immunity to fringe jumps compared to conventional far infrared (FIR) systems. Three main factors contribute to that: the high critical density associated to MIR beams, the large bandwidth provided by 40 MHz heterodyne detection, and the fact that each scan provides a "self-consistent" profile.

Fast range measurement of spot scanning proton beams using a volumetric liquid scintillator detector.

PubMed

Hui, CheukKai; Robertson, Daniel; Alsanea, Fahed; Beddar, Sam

2015-08-01

Accurate confirmation and verification of the range of spot scanning proton beams is crucial for correct dose delivery. Current methods to measure proton beam range using ionization chambers are either time-consuming or result in measurements with poor spatial resolution. The large-volume liquid scintillator detector allows real-time measurements of the entire dose profile of a spot scanning proton beam. Thus, liquid scintillator detectors are an ideal tool for measuring the proton beam range for commissioning and quality assurance. However, optical artefacts may decrease the accuracy of measuring the proton beam range within the scintillator tank. The purpose of the current study was to 1) develop a geometric calibration system to accurately calculate physical distances within the liquid scintillator detector, taking into account optical artefacts; and 2) assess the accuracy, consistency, and robustness of proton beam range measurement using the liquid scintillator detector with our geometric calibration system. The range of the proton beam was measured with the calibrated liquid scintillator system and was compared to the nominal range. Measurements were made on three different days to evaluate the setup robustness from day to day, and three sets of measurements were made for each day to evaluate the consistency from delivery to delivery. All proton beam ranges measured using the liquid scintillator system were within half a millimeter of the nominal range. The delivery-to-delivery standard deviation of the range measurement was 0.04 mm, and the day-to-day standard deviation was 0.10 mm. In addition to the accuracy and robustness demonstrated by these results when our geometric calibration system was used, the liquid scintillator system allowed the range of all 94 proton beams to be measured in just two deliveries, making the liquid scintillator detector a perfect tool for range measurement of spot scanning proton beams.

Fast range measurement of spot scanning proton beams using a volumetric liquid scintillator detector

PubMed Central

Hui, CheukKai; Robertson, Daniel; Alsanea, Fahed; Beddar, Sam

2016-01-01

Accurate confirmation and verification of the range of spot scanning proton beams is crucial for correct dose delivery. Current methods to measure proton beam range using ionization chambers are either time-consuming or result in measurements with poor spatial resolution. The large-volume liquid scintillator detector allows real-time measurements of the entire dose profile of a spot scanning proton beam. Thus, liquid scintillator detectors are an ideal tool for measuring the proton beam range for commissioning and quality assurance. However, optical artefacts may decrease the accuracy of measuring the proton beam range within the scintillator tank. The purpose of the current study was to 1) develop a geometric calibration system to accurately calculate physical distances within the liquid scintillator detector, taking into account optical artefacts; and 2) assess the accuracy, consistency, and robustness of proton beam range measurement using the liquid scintillator detector with our geometric calibration system. The range of the proton beam was measured with the calibrated liquid scintillator system and was compared to the nominal range. Measurements were made on three different days to evaluate the setup robustness from day to day, and three sets of measurements were made for each day to evaluate the consistency from delivery to delivery. All proton beam ranges measured using the liquid scintillator system were within half a millimeter of the nominal range. The delivery-to-delivery standard deviation of the range measurement was 0.04 mm, and the day-to-day standard deviation was 0.10 mm. In addition to the accuracy and robustness demonstrated by these results when our geometric calibration system was used, the liquid scintillator system allowed the range of all 94 proton beams to be measured in just two deliveries, making the liquid scintillator detector a perfect tool for range measurement of spot scanning proton beams. PMID:27274863

Advanced microwave radiometer antenna system study

NASA Technical Reports Server (NTRS)

Kummer, W. H.; Villeneuve, A. T.; Seaton, A. F.

1976-01-01

The practicability of a multi-frequency antenna for spaceborne microwave radiometers was considered in detail. The program consisted of a comparative study of various antenna systems, both mechanically and electronically scanned, in relation to specified design goals and desired system performance. The study involved several distinct tasks: definition of candidate antennas that are lightweight and that, at the specified frequencies of 5, 10, 18, 22, and 36 GHz, can provide conical scanning, dual linear polarization, and simultaneous multiple frequency operation; examination of various feed systems and phase-shifting techniques; detailed analysis of several key performance parameters such as beam efficiency, sidelobe level, and antenna beam footprint size; and conception of an antenna/feed system that could meet the design goals. Candidate antennas examined include phased arrays, lenses, and optical reflector systems. Mechanical, electrical, and performance characteristics of the various systems were tabulated for ease of comparison.

A design of endoscopic imaging system for hyper long pipeline based on wheeled pipe robot

NASA Astrophysics Data System (ADS)

Zheng, Dongtian; Tan, Haishu; Zhou, Fuqiang

2017-03-01

An endoscopic imaging system of hyper long pipeline is designed to acquire the inner surface image in advance for the hyper long pipeline detects measurement. The system consists of structured light sensors, pipe robots and control system. The pipe robot is in the form of wheel structure, with the sensor which is at the front of the vehicle body. The control system is at the tail of the vehicle body in the form of upper and lower computer. The sensor can be translated and scanned in three steps: walking, lifting and scanning, then the inner surface image can be acquired at a plurality of positions and different angles. The results of imaging experiments show that the system's transmission distance is longer, the acquisition angle is more diverse and the result is more comprehensive than the traditional imaging system, which lays an important foundation for later inner surface vision measurement.

Evaluation of the clinical efficacy of the PeTrack motion tracking system for respiratory gating in cardiac PET imaging

NASA Astrophysics Data System (ADS)

Manwell, Spencer; Chamberland, Marc J. P.; Klein, Ran; Xu, Tong; deKemp, Robert

2017-03-01

Respiratory gating is a common technique used to compensate for patient breathing motion and decrease the prevalence of image artifacts that can impact diagnoses. In this study a new data-driven respiratory gating method (PeTrack) was compared with a conventional optical tracking system. The performance of respiratory gating of the two systems was evaluated by comparing the number of respiratory triggers, patient breathing intervals and gross heart motion as measured in the respiratory-gated image reconstructions of rubidium-82 cardiac PET scans in test and control groups consisting of 15 and 8 scans, respectively. We found evidence suggesting that PeTrack is a robust patient motion tracking system that can be used to retrospectively assess patient motion in the event of failure of the conventional optical tracking system.

Point pattern match-based change detection in a constellation of previously detected objects

DOEpatents

Paglieroni, David W.

2016-06-07

A method and system is provided that applies attribute- and topology-based change detection to objects that were detected on previous scans of a medium. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, detection strength, size, elongation, orientation, etc. The locations define a three-dimensional network topology forming a constellation of previously detected objects. The change detection system stores attributes of the previously detected objects in a constellation database. The change detection system detects changes by comparing the attributes and topological consistency of newly detected objects encountered during a new scan of the medium to previously detected objects in the constellation database. The change detection system may receive the attributes of the newly detected objects as the objects are detected by an object detection system in real time.

Time-domain optical mammography Softscan: initial results on detection and characterization of breast tumors

NASA Astrophysics Data System (ADS)

Intes, Xavier; Djeziri, Salim; Ichalalene, Zahia; Mincu, Niculae; Wang, Yong; St.-Jean, Philippe; Lesage, Frédéric; Hall, David; Boas, David A.; Polyzos, Margaret

2004-10-01

Near-infrared (NIR) technology appears promising as a non-invasive clinical technique for breast cancer screening and diagnosis. The technology capitalizes on the relative transparency of human tissue in this spectral range and its sensitivity to the main components of the breast:; water, lipid and hemoglobin. In this work we present initial results obtained using the SoftScan® breast-imaging system developed by ART, Advanced Research Technologies inc., Montreal. This platform consists of a 4-wavelength time-resolved scanning system used to quantify non-invasively the local functional state of breast tissue. The different aspects of the system used to retrieve 3D optical contrast will be presented. Furthermore, preliminary data obtained from a prospective study conducted at The Royal Victoria Hospital of the McGill University Health Center in Montreal will be discussed. Analysis of the data gathered by SoftScan® demonstrated the potential of the technology in discriminating between healthy and diseased tissue.

Stress Analyzer

NASA Technical Reports Server (NTRS)

1990-01-01

SPATE 900 Dynamic Stress Analyzer is an acronym for Stress Pattern Analysis by Thermal Emission. It detects stress-induced temperature changes in a structure and indicates the degree of stress. Ometron, Inc.'s SPATE 9000 consists of a scan unit and a data display. The scan unit contains an infrared channel focused on the test structure to collect thermal radiation, and a visual channel used to set up the scan area and interrogate the stress display. Stress data is produced by detecting minute temperature changes, down to one-thousandth of a degree Centigrade, resulting from the application to the structure of dynamic loading. The electronic data processing system correlates the temperature changes with a reference signal to determine stress level.

Fluorescent scanning x-ray tomography with synchrotron radiation

NASA Astrophysics Data System (ADS)

Takeda, Tohoru; Maeda, Toshikazu; Yuasa, Tetsuya; Akatsuka, Takao; Ito, Tatsuo; Kishi, Kenichi; Wu, Jin; Kazama, Masahiro; Hyodo, Kazuyuki; Itai, Yuji

1995-02-01

Fluorescent scanning (FS) x-ray tomography was developed to detect nonradioactive tracer materials (iodine and gadolinium) in a living object. FS x-ray tomography consists of a silicon (111) channel cut monochromator, an x-ray shutter, an x-ray slit system and a collimator for detection, a scanning table for the target organ, and an x-ray detector with pure germanium. The minimal detectable dose of iodine in this experiment was 100 ng in a volume of 2 mm3 and a linear relationship was shown between the photon counts of a fluorescent x ray and the concentration of iodine contrast material. A FS x-ray tomographic image was clearly obtained with a phantom.

Development of a compact optical MEMS scanner with integrated VCSEL light source and diffractive optics

NASA Astrophysics Data System (ADS)

Krygowski, Thomas W.; Reyes, David; Rodgers, M. Steven; Smith, James H.; Warren, Mial E.; Sweatt, William C.; Blum-Spahn, Olga; Wendt, Joel R.; Asbill, Randolph E.

1999-09-01

In this work the design and initial fabrication results are reported for the components of a compact optical-MEMS laser scanning system. This system integrates a silicon MEMS laser scanner, a Vertical Cavity Surface Emitting Laser (VCSEL) and passive optical components. The MEMS scanner and VCSEL are mounted onto a fused silica substrate which serves as an optical interconnect between the devices. Two Diffractive Optical Elements (DOE's) are etched into the fused silica substrate to focus the VCSEL beam and increase the scan range. The silicon MEMS scanner consists of an actuator that continuously scans the position of a large polysilicon gold- coated shuttle containing a third DOE. Interferometric measurements show that the residual stress in the 50 micrometer X 1000 micrometer shuttle is extremely low, with a maximum deflection of only 0.18 micrometer over an 800 micrometer span for an unmetallized case and a deflection of 0.56 micrometer for the metallized case. A conservative estimate for the scan range is approximately plus or minus 4 degrees, with a spot size of about 0.5 mm, producing 50 resolvable spots. The basic system architecture, optical and MEMS design is reported in this paper, with an emphasis on the design and fabrication of the silicon MEMS scanner portion of the system.

Volume curtaining: a focus+context effect for multimodal volume visualization

NASA Astrophysics Data System (ADS)

Fairfield, Adam J.; Plasencia, Jonathan; Jang, Yun; Theodore, Nicholas; Crawford, Neil R.; Frakes, David H.; Maciejewski, Ross

2014-03-01

In surgical preparation, physicians will often utilize multimodal imaging scans to capture complementary information to improve diagnosis and to drive patient-specific treatment. These imaging scans may consist of data from magnetic resonance imaging (MR), computed tomography (CT), or other various sources. The challenge in using these different modalities is that the physician must mentally map the two modalities together during the diagnosis and planning phase. Furthermore, the different imaging modalities will be generated at various resolutions as well as slightly different orientations due to patient placement during scans. In this work, we present an interactive system for multimodal data fusion, analysis and visualization. Developed with partners from neurological clinics, this work discusses initial system requirements and physician feedback at the various stages of component development. Finally, we present a novel focus+context technique for the interactive exploration of coregistered multi-modal data.

A 94/183 GHz aircraft radiometer system for Project Storm Fury

NASA Technical Reports Server (NTRS)

Gagliano, J. A.; Stratigos, J. A.; Forsythe, R. E.; Schuchardt, J. M.; Welch, J. M.; Gallentine, D. O.

1980-01-01

A radiometer design suitable for use in NASA's WB-57F aircraft to collect data from severe storm regions was developed. The design recommended was a 94/183 GHz scanning radiometer with 3 IF channels on either side of the 183.3 GHz water vapor line and a single IF channel for a low loss atmospheric window channel at 94 GHz. The development and construction of the 94/183 GHz scanning radiometer known as the Advanced Microwave Moisture Sounder (AMMS) is presented. The radiometer scans the scene below the aircraft over an angle of + or - 45 degrees with the beamwidth of the scene viewed of approximately 2 degrees at 94 GHz and 1 degree at 183 GHz. The AMMS data collection system consists of a microcomputer used to store the radiometer data on the flight cartridge recorder, operate the stepper motor driven scanner, and collect housekeeping data such as thermistor temperature readings and aircraft time code.

A Deep-towed Digital Multichannel Seismic Streamer For Very High-resolution Studies Of Marine Subsurface Structures

NASA Astrophysics Data System (ADS)

Breitzke, M.; Bialas, J.; Inggas Working Group

A deep-towed digital multichannel seismic streamer and side scan sonar system has been developed to collect marine seismic data with a very high lateral in- and cross- line resolution particularly in regions of special interest for gas hydrate research. As marine seismic sources conventional air-, GI or waterguns will be shot close to the sea surface. A depressor of about 2 tons weight ensures the slightly buoyant deep-towed system to keep in depth. The streamer is a modular digital system which can be operated in water depths up to 6000 m. At this stage of development, it consists of a 50 m lead-in cable towed behind the side scan sonar fish and 26 single nodes for each channel. Each node houses a sin- gle hydrophone, low- and high-cut filter, preamplifier and 24-bit AD converter. Three special engineering nodes additionally include a pressure sensor and compass which provide information on the depth of the node and on its geographical position relative to the ship. Nodes are interchangeable and can arbitrarily be connected by cables of 1 or 6.5 m length. A minimum sample interval of 0.25 ms allows to use sufficiently high- frequency seismic sources to guarantee both a very high vertical and lateral resolution. Data are stored both underwater on a linux-based PC with 120 GB storage capacity installed in a pressure vessel mounted on the side scan sonar fish, and onboard on a PC running a data acquisition program and a DLT device. Data are transferred between underwater and onboard systems via telemetry controlled by a second linux-based PC onboard, using coaxial cable or fibre optic technology. The exact position of the side scan sonar fish is determined by the ultra-short base line (USBL) Posidonia system. It mainly consists of a hull-mounted acoustic unit (antenna) and a responder mounted on the side scan sonar fish. Additionally, the three engineering nodes measure the depth and heading of the streamer at three positions relative to the side scan sonar fish. All deep-towed and laboratory components are synchronized by DGPS time based trigger signals. This deep-towed system will first be tested during the SO162 cruise of RV Sonne (21.2. - 12.3.02) off Peru and Ecuador along profile lines where conventional multi- channel seismic reflection data have already been collected during a fomer cruise.

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - LEAD IN DUST WIPE MEASUREMENT TECHNOLOGY, PALINTEST, SCANNING ANALYZER , SA-5000 SYSTEM

EPA Science Inventory

ETV works in partnership with recognized standards and testing organizations and stakeholder groups consisting of regulators, buyers, and vendor organizations, with the full participation of individual technology developers. The program evaluates the performance of innovative

CRionScan: A stand-alone real time controller designed to perform ion beam imaging, dose controlled irradiation and proton beam writing

NASA Astrophysics Data System (ADS)

Daudin, L.; Barberet, Ph.; Serani, L.; Moretto, Ph.

2013-07-01

High resolution ion microbeams, usually used to perform elemental mapping, low dose targeted irradiation or ion beam lithography needs a very flexible beam control system. For this purpose, we have developed a dedicated system (called “CRionScan”), on the AIFIRA facility (Applications Interdisciplinaires des Faisceaux d'Ions en Région Aquitaine). It consists of a stand-alone real-time scanning and imaging instrument based on a Compact Reconfigurable Input/Output (Compact RIO) device from National Instruments™. It is based on a real-time controller, a Field Programmable Gate Array (FPGA), input/output modules and Ethernet connectivity. We have implemented a fast and deterministic beam scanning system interfaced with our commercial data acquisition system without any hardware development. CRionScan is built under LabVIEW™ and has been used on AIFIRA's nanobeam line since 2009 (Barberet et al., 2009, 2011) [1,2]. A Graphical User Interface (GUI) embedded in the Compact RIO as a web page is used to control the scanning parameters. In addition, a fast electrostatic beam blanking trigger has been included in the FPGA and high speed counters (15 MHz) have been implemented to perform dose controlled irradiation and on-line images on the GUI. Analog to Digital converters are used for the beam current measurement and in the near future for secondary electrons imaging. Other functionalities have been integrated in this controller like LED lighting using Pulse Width Modulation and a “NIM Wilkinson ADC” data acquisition.

Automated detection of analyzable metaphase chromosome cells depicted on scanned digital microscopic images

NASA Astrophysics Data System (ADS)

Qiu, Yuchen; Wang, Xingwei; Chen, Xiaodong; Li, Yuhua; Liu, Hong; Li, Shibo; Zheng, Bin

2010-02-01

Visually searching for analyzable metaphase chromosome cells under microscopes is quite time-consuming and difficult. To improve detection efficiency, consistency, and diagnostic accuracy, an automated microscopic image scanning system was developed and tested to directly acquire digital images with sufficient spatial resolution for clinical diagnosis. A computer-aided detection (CAD) scheme was also developed and integrated into the image scanning system to search for and detect the regions of interest (ROI) that contain analyzable metaphase chromosome cells in the large volume of scanned images acquired from one specimen. Thus, the cytogeneticists only need to observe and interpret the limited number of ROIs. In this study, the high-resolution microscopic image scanning and CAD performance was investigated and evaluated using nine sets of images scanned from either bone marrow (three) or blood (six) specimens for diagnosis of leukemia. The automated CAD-selection results were compared with the visual selection. In the experiment, the cytogeneticists first visually searched for the analyzable metaphase chromosome cells from specimens under microscopes. The specimens were also automated scanned and followed by applying the CAD scheme to detect and save ROIs containing analyzable cells while deleting the others. The automated selected ROIs were then examined by a panel of three cytogeneticists. From the scanned images, CAD selected more analyzable cells than initially visual examinations of the cytogeneticists in both blood and bone marrow specimens. In general, CAD had higher performance in analyzing blood specimens. Even in three bone marrow specimens, CAD selected 50, 22, 9 ROIs, respectively. Except matching with the initially visual selection of 9, 7, and 5 analyzable cells in these three specimens, the cytogeneticists also selected 41, 15 and 4 new analyzable cells, which were missed in initially visual searching. This experiment showed the feasibility of applying this CAD-guided high-resolution microscopic image scanning system to prescreen and select ROIs that may contain analyzable metaphase chromosome cells. The success and the further improvement of this automated scanning system may have great impact on the future clinical practice in genetic laboratories to detect and diagnose diseases.

A prototype table-top inverse-geometry volumetric CT system.

PubMed

Schmidt, Taly Gilat; Star-Lack, Josh; Bennett, N Robert; Mazin, Samuel R; Solomon, Edward G; Fahrig, Rebecca; Pelc, Norbert J

2006-06-01

A table-top volumetric CT system has been implemented that is able to image a 5-cm-thick volume in one circular scan with no cone-beam artifacts. The prototype inverse-geometry CT (IGCT) scanner consists of a large-area, scanned x-ray source and a detector array that is smaller in the transverse direction. The IGCT geometry provides sufficient volumetric sampling because the source and detector have the same axial, or slice direction, extent. This paper describes the implementation of the table-top IGCT scanner, which is based on the NexRay Scanning-Beam Digital X-ray system (NexRay, Inc., Los Gatos, CA) and an investigation of the system performance. The alignment and flat-field calibration procedures are described, along with a summary of the reconstruction algorithm. The resolution and noise performance of the prototype IGCT system are studied through experiments and further supported by analytical predictions and simulations. To study the presence of cone-beam artifacts, a "Defrise" phantom was scanned on both the prototype IGCT scanner and a micro CT system with a +/-5 cone angle for a 4.5-cm volume thickness. Images of inner ear specimens are presented and compared to those from clinical CT systems. Results showed that the prototype IGCT system has a 0.25-mm isotropic resolution and that noise comparable to that from a clinical scanner with equivalent spatial resolution is achievable. The measured MTF and noise values agreed reasonably well with theoretical predictions and computer simulations. The IGCT system was able to faithfully reconstruct the laminated pattern of the Defrise phantom while the micro CT system suffered severe cone-beam artifacts for the same object. The inner ear acquisition verified that the IGCT system can image a complex anatomical object, and the resulting images exhibited more high-resolution details than the clinical CT acquisition. Overall, the successful implementation of the prototype system supports the IGCT concept for single-rotation volumetric scanning free from cone-beam artifacts.

Fast Measurement and Reconstruction of Large Workpieces with Freeform Surfaces by Combining Local Scanning and Global Position Data

PubMed Central

Chen, Zhe; Zhang, Fumin; Qu, Xinghua; Liang, Baoqiu

2015-01-01

In this paper, we propose a new approach for the measurement and reconstruction of large workpieces with freeform surfaces. The system consists of a handheld laser scanning sensor and a position sensor. The laser scanning sensor is used to acquire the surface and geometry information, and the position sensor is utilized to unify the scanning sensors into a global coordinate system. The measurement process includes data collection, multi-sensor data fusion and surface reconstruction. With the multi-sensor data fusion, errors accumulated during the image alignment and registration process are minimized, and the measuring precision is significantly improved. After the dense accurate acquisition of the three-dimensional (3-D) coordinates, the surface is reconstructed using a commercial software piece, based on the Non-Uniform Rational B-Splines (NURBS) surface. The system has been evaluated, both qualitatively and quantitatively, using reference measurements provided by a commercial laser scanning sensor. The method has been applied for the reconstruction of a large gear rim and the accuracy is up to 0.0963 mm. The results prove that this new combined method is promising for measuring and reconstructing the large-scale objects with complex surface geometry. Compared with reported methods of large-scale shape measurement, it owns high freedom in motion, high precision and high measurement speed in a wide measurement range. PMID:26091396

Panoramic attitude sensor for Radio Astronomy Explorer B

NASA Technical Reports Server (NTRS)

Thomsen, R.

1973-01-01

An instrument system to acquire attitude determination data for the RAE-B spacecraft was designed and built. The system consists of an electronics module and two optical scanner heads. Each scanner head has an optical scanner with a field of view of 0.7 degrees diameter which scans the sky and measures the position of the moon, earth and sun relative to the spacecraft. This scanning is accomplished in either of two modes. When the spacecraft is spinning, the scanner operates in spherical mode, with the spacecraft spin providing the slow sweep of lattitude to scan the entire sky. After the spacecraft is placed in lunar orbit and despun, the scanner will operate in planar mode, advancing at a rate of 5.12 seconds per revolution in a fixed plane parallel to the spacecraft Z axis. This scan will cross and measure the moon horizons with every revolution. Each scanner head also has a sun slit which is aligned parallel to the spin axis of the spacecraft and which provides a sun pulse each revolution of the spacecraft. The electronics module provides the command and control, data processing and housekeeping functions.

N-SCAN: new vibromodulation system for detection and monitoring of cracks and other contact-type defects

NASA Astrophysics Data System (ADS)

Donskoy, Dmitri; Ekimov, Alexander; Luzzato, Emile; Lottiaux, Jean-Louis; Stoupin, Stanislav; Zagrai, Andrei

2003-08-01

In recent years, innovative vibro-modulation technique has been introduced for detection of contact-type interfaces such as cracks, debondings, and delaminations. The technique utilizes the effect of nonlinear interaction of ultrasound and vibrations at the interface of the defect. Vibration varies on the contact area of the interface modulating passing through ultrasonic wave. The modulation manifests itself as additional side-band spectral components with the combination frequencies in the spectrum of the received signal. The presence of these components allows for detection and differentiation of the contact-type defects from other structural and material inhomogeneities. Vibro-modulation technique has been implemented in N-SCAN damage detection system. The system consists of a digital synthesizer, high and low frequency amplifiers, a magnetostrictive shaker, ultrasonic transducers and a PC-based data acquisition/processing station with N-SCAN software. The ability of the system to detect contact-type defects was experimentally verified using specimens of simple and complex geometries made of steel, aluminum, composites and other structural materials. N-SCAN proved to be very effective for nondestructive testing of full-scale structures ranging from 24 foot-long gun barrels to stainless steel pipes used in nuclear power plants. Among advantages of the system are applicability for the wide range of structural materials and for structures with complex geometries, real time data processing, convenient interface for system operation, simplicity of interpretation of results, no need for sensor scanning along structure, onsite inspection of large structures at a fraction of time as compared with conventional techniques. This paper describes the basic principles of nonlinear vibro-modulation NDE technique, some theoretical background for nonlinear interaction and justification of signal processing algorithm. It is also presents examples of practical implementation and application of the technique.

Evaluation of portable CT scanners for otologic image-guided surgery

PubMed Central

Balachandran, Ramya; Schurzig, Daniel; Fitzpatrick, J Michael; Labadie, Robert F

2011-01-01

Purpose Portable CT scanners are beneficial for diagnosis in the intensive care unit, emergency room, and operating room. Portable fixed-base versus translating-base CT systems were evaluated for otologic image-guided surgical (IGS) applications based on geometric accuracy and utility for percutaneous cochlear implantation. Methods Five cadaveric skulls were fitted with fiducial markers and scanned using both a translating-base, 8-slice CT scanner (CereTom®) and a fixed-base, flat-panel, volume-CT (fpVCT) scanner (Xoran xCAT®). Images were analyzed for: (a) subjective quality (i.e. noise), (b) consistency of attenuation measurements (Hounsfield units) across similar tissue, and (c) geometric accuracy of fiducial marker positions. The utility of these scanners in clinical IGS cases was tested. Results Five cadaveric specimens were scanned using each of the scanners. The translating-base, 8-slice CT scanner had spatially consistent Hounsfield units, and the image quality was subjectively good. However, because of movement variations during scanning, the geometric accuracy of fiducial marker positions was low. The fixed-base, fpVCT system had high spatial resolution, but the images were noisy and had spatially inconsistent attenuation measurements; while the geometric representation of the fiducial markers was highly accurate. Conclusion Two types of portable CT scanners were evaluated for otologic IGS. The translating-base, 8-slice CT scanner provided better image quality than a fixed-base, fpVCT scanner. However, the inherent error in three-dimensional spatial relationships by the translating-based system makes it suboptimal for otologic IGS use. PMID:21779768

TH-CD-207B-03: How to Quantify Temporal Resolution in X-Ray MDCT Imaging?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Budde, A; GE Healthcare Technologies, Madison, WI; Li, Y

Purpose: In modern CT scanners, a quantitative metric to assess temporal response, namely, to quantify the temporal resolution (TR), remains elusive. Rough surrogate metrics, such as half of the gantry rotation time for single source CT, a quarter of the gantry rotation time for dual source CT, or measurements of motion artifact’s size, shape, or intensity have previously been used. In this work, a rigorous framework which quantifies TR and a practical measurement method are developed. Methods: A motion phantom was simulated which consisted of a single rod that is in motion except during a static period at the temporalmore » center of the scan, termed the TR window. If the image of the motion scan has negligible motion artifacts compared to an image from a totally static scan, then the system has a TR no worse than the TR window used. By repeating this comparison with varying TR windows, the TR of the system can be accurately determined. Motion artifacts were also visually assessed and the TR was measured across varying rod motion speeds, directions, and locations. Noiseless fan beam acquisitions were simulated and images were reconstructed with a short-scan image reconstruction algorithm. Results: The size, shape, and intensity of motion artifacts varied when the rod speed, direction, or location changed. TR measured using the proposed method, however, was consistent across rod speeds, directions, and locations. Conclusion: Since motion artifacts vary depending upon the motion speed, direction, and location, they are not suitable for measuring TR. In this work, a CT system with a specified TR is defined as having the ability to produce a static image with negligible motion artifacts, no matter what motion occurs outside of a static window of width TR. This framework allows for practical measurement of temporal resolution in clinical CT imaging systems. Funding support: GE Healthcare; Conflict of Interest: Employee, GE Healthcare.« less

Review of MEMS differential scanning calorimetry for biomolecular study

NASA Astrophysics Data System (ADS)

Yu, Shifeng; Wang, Shuyu; Lu, Ming; Zuo, Lei

2017-12-01

Differential scanning calorimetry (DSC) is one of the few techniques that allow direct determination of enthalpy values for binding reactions and conformational transitions in biomolecules. It provides the thermodynamics information of the biomolecules which consists of Gibbs free energy, enthalpy and entropy in a straightforward manner that enables deep understanding of the structure function relationship in biomolecules such as the folding/unfolding of protein and DNA, and ligand bindings. This review provides an up to date overview of the applications of DSC in biomolecular study such as the bovine serum albumin denaturation study, the relationship between the melting point of lysozyme and the scanning rate. We also introduce the recent advances of the development of micro-electro-mechanic-system (MEMS) based DSCs.

Electrostatic Evaluation of the SRB Velostat(Trademark) Pads

NASA Technical Reports Server (NTRS)

Buhler, Charles R.; Calle, Carlos I.

2007-01-01

During RSRM Grain inspection, pads constructed of Velostat are grounded and installed in the RSRM bore enabling inspectors to move throughout the bore during the inspection. Velostat pads are installed by grounding the first pad installed and subsequent pads are installed overlapping the previously installed pad maintaining a conductive path to facility ground. Pads are removed upon completion of the inspection in a reverse fashion. As the pads are removed scanning of propellant surfaces is performed per OMRS. During PPICI Audit of B5308.006 (Forward Segment Grain Inspection) in October 07 one audit finding noted that electrostatic scanning of propellant surfaces was being performed during removal of conductive pads following grain inspection. ATK does not perform electrostatic scanning of propellant surfaces during pad removal following final inspection at the plant. The integrated team consisting of NASA SE, USA SE, USA QE, ATK LSS, ATK Systems Safety and ATK DE concurred that electrostatic scanning of propellant surfaces was unnecessary as the conductive pads are grounded. Additional time spent in bore performing scanning presents itself as additional risk. Technicians reported that they have never seen any voltage readings while scanning propellant surfaces during pad removal. USA Systems engineering has written KB 17530 in response to the finding which will delete the requirement (item 2 B47GEN.ll0) to scan propellant surfaces during pad removal. As a result of an E3 panel discussion on December 13, 2007, it was decided that verification of the electrical grounding of the Velostat pads be verified.

Spatial-scanning hyperspectral imaging probe for bio-imaging applications

NASA Astrophysics Data System (ADS)

Lim, Hoong-Ta; Murukeshan, Vadakke Matham

2016-03-01

The three common methods to perform hyperspectral imaging are the spatial-scanning, spectral-scanning, and snapshot methods. However, only the spectral-scanning and snapshot methods have been configured to a hyperspectral imaging probe as of today. This paper presents a spatial-scanning (pushbroom) hyperspectral imaging probe, which is realized by integrating a pushbroom hyperspectral imager with an imaging probe. The proposed hyperspectral imaging probe can also function as an endoscopic probe by integrating a custom fabricated image fiber bundle unit. The imaging probe is configured by incorporating a gradient-index lens at the end face of an image fiber bundle that consists of about 50 000 individual fiberlets. The necessary simulations, methodology, and detailed instrumentation aspects that are carried out are explained followed by assessing the developed probe's performance. Resolution test targets such as United States Air Force chart as well as bio-samples such as chicken breast tissue with blood clot are used as test samples for resolution analysis and for performance validation. This system is built on a pushbroom hyperspectral imaging system with a video camera and has the advantage of acquiring information from a large number of spectral bands with selectable region of interest. The advantages of this spatial-scanning hyperspectral imaging probe can be extended to test samples or tissues residing in regions that are difficult to access with potential diagnostic bio-imaging applications.

Multiple-mouse MRI with multiple arrays of receive coils.

PubMed

Ramirez, Marc S; Esparza-Coss, Emilio; Bankson, James A

2010-03-01

Compared to traditional single-animal imaging methods, multiple-mouse MRI has been shown to dramatically improve imaging throughput and reduce the potentially prohibitive cost for instrument access. To date, up to a single radiofrequency coil has been dedicated to each animal being simultaneously scanned, thus limiting the sensitivity, flexibility, and ultimate throughput. The purpose of this study was to investigate the feasibility of multiple-mouse MRI with a phased-array coil dedicated to each animal. A dual-mouse imaging system, consisting of a pair of two-element phased-array coils, was developed and used to achieve acceleration factors greater than the number of animals scanned at once. By simultaneously scanning two mice with a retrospectively gated cardiac cine MRI sequence, a 3-fold acceleration was achieved with signal-to-noise ratio in the heart that is equivalent to that achieved with an unaccelerated scan using a commercial mouse birdcage coil. (c) 2010 Wiley-Liss, Inc.

Development of a Compact Optical-MEMS Scanner with Integrated VCSEL Light Source and Diffractive Optics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krygowski, Thomas W.; Reyes, David; Rodgers, M. Steven

1999-06-30

In this work the design and initial fabrication results are reported for the components of a compact optical-MEMS laser scanning system. This system integrates a silicon MEMS laser scanner, a Vertical Cavity Surface Emitting Laser (VCSEL) and passive optical components. The MEMS scanner and VCSEL are mounted onto a fused silica substrate which serves as an optical interconnect between the devices. Two Diffractive Optical Elements (DOEs) are etched into the fused silica substrate to focus the VCSEL beam and increase the scan range. The silicon MEMS scanner consists of an actuator that continuously scans the position of a large polysiliconmore » gold-coated shuttle containing a third DOE. Interferometric measurements show that the residual stress in the 500 {micro}m x 1000 {micro}m shuttle is extremely low, with a maximum deflection of only 0.18{micro}m over an 800 {micro}m span for an unmetallized case and a deflection of 0.56{micro}m for the metallized case. A conservative estimate for the scan range is {approximately}{+-}4{degree}, with a spot size of about 0.5 mm, producing 50 resolvable spots. The basic system architecture, optical and MEMS design is reported in this paper, with an emphasis on the design and fabrication of the silicon MEMS scanner portion of the system.« less

Imaging properties and its improvements of scanning/imaging x-ray microscope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takeuchi, Akihisa, E-mail: take@spring8.or.jp; Uesugi, Kentaro; Suzuki, Yoshio

A scanning / imaging X-ray microscope (SIXM) system has been developed at SPring-8. The SIXM consists of a scanning X-ray microscope with a one-dimensional (1D) X-ray focusing device and an imaging (full-field) X-ray microscope with a 1D X-ray objective. The motivation of the SIXM system is to realize a quantitative and highly-sensitive multimodal 3D X-ray tomography by taking advantages of both the scanning X-ray microscope using multi-pixel detector and the imaging X-ray microscope. Data acquisition process of a 2D image is completely different between in the horizontal direction and in the vertical direction; a 1D signal is obtained with themore » linear-scanning while the other dimensional signal is obtained with the imaging optics. Such condition have caused a serious problem on the imaging properties that the imaging quality in the vertical direction has been much worse than that in the horizontal direction. In this paper, two approaches to solve this problem will be presented. One is introducing a Fourier transform method for phase retrieval from one phase derivative image, and the other to develop and employ a 1D diffuser to produce an asymmetrical coherent illumination.« less

Full cycle rapid scan EPR deconvolution algorithm.

PubMed

Tseytlin, Mark

2017-08-01

Rapid scan electron paramagnetic resonance (RS EPR) is a continuous-wave (CW) method that combines narrowband excitation and broadband detection. Sinusoidal magnetic field scans that span the entire EPR spectrum cause electron spin excitations twice during the scan period. Periodic transient RS signals are digitized and time-averaged. Deconvolution of absorption spectrum from the measured full-cycle signal is an ill-posed problem that does not have a stable solution because the magnetic field passes the same EPR line twice per sinusoidal scan during up- and down-field passages. As a result, RS signals consist of two contributions that need to be separated and postprocessed individually. Deconvolution of either of the contributions is a well-posed problem that has a stable solution. The current version of the RS EPR algorithm solves the separation problem by cutting the full-scan signal into two half-period pieces. This imposes a constraint on the experiment; the EPR signal must completely decay by the end of each half-scan in order to not be truncated. The constraint limits the maximum scan frequency and, therefore, the RS signal-to-noise gain. Faster scans permit the use of higher excitation powers without saturating the spin system, translating into a higher EPR sensitivity. A stable, full-scan algorithm is described in this paper that does not require truncation of the periodic response. This algorithm utilizes the additive property of linear systems: the response to a sum of two inputs is equal the sum of responses to each of the inputs separately. Based on this property, the mathematical model for CW RS EPR can be replaced by that of a sum of two independent full-cycle pulsed field-modulated experiments. In each of these experiments, the excitation power equals to zero during either up- or down-field scan. The full-cycle algorithm permits approaching the upper theoretical scan frequency limit; the transient spin system response must decay within the scan period. Separation of the interfering up- and down-field scan responses remains a challenge for reaching the full potential of this new method. For this reason, only a factor of two increase in the scan rate was achieved, in comparison with the standard half-scan RS EPR algorithm. It is important for practical use that faster scans not necessarily increase the signal bandwidth because acceleration of the Larmor frequency driven by the changing magnetic field changes its sign after passing the inflection points on the scan. The half-scan and full-scan algorithms are compared using a LiNC-BuO spin probe of known line-shape, demonstrating that the new method produces stable solutions when RS signals do not completely decay by the end of each half-scan. Copyright © 2017 Elsevier Inc. All rights reserved.

Full cycle rapid scan EPR deconvolution algorithm

NASA Astrophysics Data System (ADS)

Tseytlin, Mark

2017-08-01

Rapid scan electron paramagnetic resonance (RS EPR) is a continuous-wave (CW) method that combines narrowband excitation and broadband detection. Sinusoidal magnetic field scans that span the entire EPR spectrum cause electron spin excitations twice during the scan period. Periodic transient RS signals are digitized and time-averaged. Deconvolution of absorption spectrum from the measured full-cycle signal is an ill-posed problem that does not have a stable solution because the magnetic field passes the same EPR line twice per sinusoidal scan during up- and down-field passages. As a result, RS signals consist of two contributions that need to be separated and postprocessed individually. Deconvolution of either of the contributions is a well-posed problem that has a stable solution. The current version of the RS EPR algorithm solves the separation problem by cutting the full-scan signal into two half-period pieces. This imposes a constraint on the experiment; the EPR signal must completely decay by the end of each half-scan in order to not be truncated. The constraint limits the maximum scan frequency and, therefore, the RS signal-to-noise gain. Faster scans permit the use of higher excitation powers without saturating the spin system, translating into a higher EPR sensitivity. A stable, full-scan algorithm is described in this paper that does not require truncation of the periodic response. This algorithm utilizes the additive property of linear systems: the response to a sum of two inputs is equal the sum of responses to each of the inputs separately. Based on this property, the mathematical model for CW RS EPR can be replaced by that of a sum of two independent full-cycle pulsed field-modulated experiments. In each of these experiments, the excitation power equals to zero during either up- or down-field scan. The full-cycle algorithm permits approaching the upper theoretical scan frequency limit; the transient spin system response must decay within the scan period. Separation of the interfering up- and down-field scan responses remains a challenge for reaching the full potential of this new method. For this reason, only a factor of two increase in the scan rate was achieved, in comparison with the standard half-scan RS EPR algorithm. It is important for practical use that faster scans not necessarily increase the signal bandwidth because acceleration of the Larmor frequency driven by the changing magnetic field changes its sign after passing the inflection points on the scan. The half-scan and full-scan algorithms are compared using a LiNC-BuO spin probe of known line-shape, demonstrating that the new method produces stable solutions when RS signals do not completely decay by the end of each half-scan.

Expert systems for automated correlation and interpretation of wireline logs

USGS Publications Warehouse

Olea, R.A.

1994-01-01

CORRELATOR is an interactive computer program for lithostratigraphic correlation of wireline logs able to store correlations in a data base with a consistency, accuracy, speed, and resolution that are difficult to obtain manually. The automatic determination of correlations is based on the maximization of a weighted correlation coefficient using two wireline logs per well. CORRELATOR has an expert system to scan and flag incongruous correlations in the data base. The user has the option to accept or disregard the advice offered by the system. The expert system represents knowledge through production rules. The inference system is goal-driven and uses backward chaining to scan through the rules. Work in progress is used to illustrate the potential that a second expert system with a similar architecture for interpreting dip diagrams could have to identify episodes-as those of interest in sequence stratigraphy and fault detection- and annotate them in the stratigraphic column. Several examples illustrate the presentation. ?? 1994 International Association for Mathematical Geology.

Multichannel scanning radiometer for remote sensing cloud physical parameters

NASA Technical Reports Server (NTRS)

Curran, R. J.; Kyle, H. L.; Blaine, L. R.; Smith, J.; Clem, T. D.

1981-01-01

A multichannel scanning radiometer developed for remote observation of cloud physical properties is described. Consisting of six channels in the near infrared and one channel in the thermal infrared, the instrument can observe cloud physical parameters such as optical thickness, thermodynamic phase, cloud top altitude, and cloud top temperature. Measurement accuracy is quantified through flight tests on the NASA CV-990 and the NASA WB-57F, and is found to be limited by the harsh environment of the aircraft at flight altitude. The electronics, data system, and calibration of the instrument are also discussed.

40 CFR 86.1806-04 - On-board diagnostics.

Code of Federal Regulations, 2013 CFR

2013-07-01

... codes shall be consistent with SAE J2012 “Diagnostic Trouble Code Definitions—Equivalent to ISO/DIS... sent to the scan tool over a J1850 data link shall use the Cyclic Redundancy Check and the three byte..., definitions and abbreviations shall be formatted according to SAE J1930 “Electrical/Electronic Systems...

40 CFR 86.1806-04 - On-board diagnostics.

Code of Federal Regulations, 2012 CFR

2012-07-01

... codes shall be consistent with SAE J2012 “Diagnostic Trouble Code Definitions—Equivalent to ISO/DIS... sent to the scan tool over a J1850 data link shall use the Cyclic Redundancy Check and the three byte..., definitions and abbreviations shall be formatted according to SAE J1930 “Electrical/Electronic Systems...

40 CFR 86.1806-04 - On-board diagnostics.

Code of Federal Regulations, 2011 CFR

2011-07-01

... codes shall be consistent with SAE J2012 “Diagnostic Trouble Code Definitions—Equivalent to ISO/DIS... sent to the scan tool over a J1850 data link shall use the Cyclic Redundancy Check and the three byte..., definitions and abbreviations shall be formatted according to SAE J1930 “Electrical/Electronic Systems...

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

PubMed Central

Shibata, Kazuhiro; Itoh, Masayoshi; Aizawa, Katsunori; Nagaoka, Sumiharu; Sasaki, Nobuya; Carninci, Piero; Konno, Hideaki; Akiyama, Junichi; Nishi, Katsuo; Kitsunai, Tokuji; Tashiro, Hideo; Itoh, Mari; Sumi, Noriko; Ishii, Yoshiyuki; Nakamura, Shin; Hazama, Makoto; Nishine, Tsutomu; Harada, Akira; Yamamoto, Rintaro; Matsumoto, Hiroyuki; Sakaguchi, Sumito; Ikegami, Takashi; Kashiwagi, Katsuya; Fujiwake, Syuji; Inoue, Kouji; Togawa, Yoshiyuki; Izawa, Masaki; Ohara, Eiji; Watahiki, Masanori; Yoneda, Yuko; Ishikawa, Tomokazu; Ozawa, Kaori; Tanaka, Takumi; Matsuura, Shuji; Kawai, Jun; Okazaki, Yasushi; Muramatsu, Masami; Inoue, Yorinao; Kira, Akira; Hayashizaki, Yoshihide

2000-01-01

The RIKEN high-throughput 384-format sequencing pipeline (RISA system) including a 384-multicapillary sequencer (the so-called RISA sequencer) was developed for the RIKEN mouse encyclopedia project. The RISA system consists of colony picking, template preparation, sequencing reaction, and the sequencing process. A novel high-throughput 384-format capillary sequencer system (RISA sequencer system) was developed for the sequencing process. This system consists of a 384-multicapillary auto sequencer (RISA sequencer), a 384-multicapillary array assembler (CAS), and a 384-multicapillary casting device. The RISA sequencer can simultaneously analyze 384 independent sequencing products. The optical system is a scanning system chosen after careful comparison with an image detection system for the simultaneous detection of the 384-capillary array. This scanning system can be used with any fluorescent-labeled sequencing reaction (chain termination reaction), including transcriptional sequencing based on RNA polymerase, which was originally developed by us, and cycle sequencing based on thermostable DNA polymerase. For long-read sequencing, 380 out of 384 sequences (99.2%) were successfully analyzed and the average read length, with more than 99% accuracy, was 654.4 bp. A single RISA sequencer can analyze 216 kb with >99% accuracy in 2.7 h (90 kb/h). For short-read sequencing to cluster the 3′ end and 5′ end sequencing by reading 350 bp, 384 samples can be analyzed in 1.5 h. We have also developed a RISA inoculator, RISA filtrator and densitometer, RISA plasmid preparator which can handle throughput of 40,000 samples in 17.5 h, and a high-throughput RISA thermal cycler which has four 384-well sites. The combination of these technologies allowed us to construct the RISA system consisting of 16 RISA sequencers, which can process 50,000 DNA samples per day. One haploid genome shotgun sequence of a higher organism, such as human, mouse, rat, domestic animals, and plants, can be revealed by seven RISA systems within one month. PMID:11076861

Multi-mounted X-ray cone-beam computed tomography

NASA Astrophysics Data System (ADS)

Fu, Jian; Wang, Jingzheng; Guo, Wei; Peng, Peng

2018-04-01

As a powerful nondestructive inspection technique, X-ray computed tomography (X-CT) has been widely applied to clinical diagnosis, industrial production and cutting-edge research. Imaging efficiency is currently one of the major obstacles for the applications of X-CT. In this paper, a multi-mounted three dimensional cone-beam X-CT (MM-CBCT) method is reported. It consists of a novel multi-mounted cone-beam scanning geometry and the corresponding three dimensional statistical iterative reconstruction algorithm. The scanning geometry is the most iconic design and significantly different from the current CBCT systems. Permitting the cone-beam scanning of multiple objects simultaneously, the proposed approach has the potential to achieve an imaging efficiency orders of magnitude greater than the conventional methods. Although multiple objects can be also bundled together and scanned simultaneously by the conventional CBCT methods, it will lead to the increased penetration thickness and signal crosstalk. In contrast, MM-CBCT avoids substantially these problems. This work comprises a numerical study of the method and its experimental verification using a dataset measured with a developed MM-CBCT prototype system. This technique will provide a possible solution for the CT inspection in a large scale.

WE-G-BRF-07: Non-Circular Scanning Trajectories with Varian Developer Mode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, A; Pearson, E; Pan, X

2014-06-15

Purpose: Cone-beam CT (CBCT) in image-guide radiation therapy (IGRT) typicallyacquires scan data via the circular trajectory of the linearaccelerator's (linac) gantry rotation. Though this lends itself toanalytic reconstruction algorithms like FDK, iterative reconstructionalgorithms allow for a broader range of scanning trajectories. Weimplemented a non-circular scanning trajectory with Varian's TrueBeamDeveloper Mode and performed some preliminary reconstructions toverify the geometry. Methods: We used TrueBeam Developer Mode to program a new scanning trajectorythat increases the field of view (FOV) along the gantry rotation axiswithout moving the patient. This trajectory consisted of moving thegantry in a circle, then translating the source and detector alongmore » theaxial direction before acquiring another circular scan 19 cm away fromthe first. The linear portion of the trajectory includes an additional4.5 cm above and below the axial planes of the source's circularrotation. We scanned a calibration phantom consisting of a lucite tubewith a spiral pattern of CT spots and used the maximum-likelihoodalgorithm to iteratively reconstruct the CBCT volume. Results: With the TrueBeam trajectory definition, we acquired projection dataof the calibration phantom using the previously described trajectory.We obtained a scan of the treatment couch for log normalization byscanning with the same trajectory but without the phantom present.Using the nominal geometric parameters reported in the projectionheaders with our iterative reconstruction algorithm, we obtained acorrect reconstruction of the calibration phantom. Conclusion: The ability to implement new scanning trajectories with the TrueBeamDeveloper Mode enables us access to a new parameter space for imagingwith CBCT for IGRT. Previous simulations and simple dual circle scanshave shown iterative reconstruction with non-circular trajectories canincrease the axial FOV with CBCT. Use of Developer Mode allowsexperimentally testing these and other new scanning trajectories. Support was provided in part by the University of Chicago Research Computing Center, Varian Medical Systems, and NIH Grants 1RO1CA120540, T32EB002103, S10 RR021039 and P30 CA14599. The contents of this work are solely the responsibility of the authors and do not necessarily represent the official views of the supporting organizations.« less

X-ray phase scanning setup for non-destructive testing using Talbot-Lau interferometer

NASA Astrophysics Data System (ADS)

Bachche, S.; Nonoguchi, M.; Kato, K.; Kageyama, M.; Koike, T.; Kuribayashi, M.; Momose, A.

2016-09-01

X-ray grating interferometry has a great potential for X-ray phase imaging over conventional X-ray absorption imaging which does not provide significant contrast for weakly absorbing objects and soft biological tissues. X-ray Talbot and Talbot-Lau interferometers which are composed of transmission gratings and measure the differential X-ray phase shifts have gained popularity because they operate with polychromatic beams. In X-ray radiography, especially for nondestructive testing in industrial applications, the feasibility of continuous sample scanning is not yet completely revealed. A scanning setup is frequently advantageous when compared to a direct 2D static image acquisition in terms of field of view, exposure time, illuminating radiation, etc. This paper demonstrates an efficient scanning setup for grating-based Xray phase imaging using laboratory-based X-ray source. An apparatus consisting of an X-ray source that emits X-rays vertically, optical gratings and a photon-counting detector was used with which continuously moving objects across the field of view as that of conveyor belt system can be imaged. The imaging performance of phase scanner was tested by scanning a long continuous moving sample at a speed of 5 mm/s and absorption, differential-phase and visibility images were generated by processing non-uniform moire movie with our specially designed phase measurement algorithm. A brief discussion on the feasibility of phase scanner with scanning setup approach including X-ray phase imaging performance is reported. The successful results suggest a breakthrough for scanning objects those are moving continuously on conveyor belt system non-destructively using the scheme of X-ray phase imaging.

Efficient system for wavenumber-frequency analysis of underwater structures

NASA Astrophysics Data System (ADS)

Boober, Walter H.; Morton, David; Gedney, Charles; Abbot, Philip

1998-06-01

A watertight housing was developed to a low a scanning laser vibrometer (SLV) system to work underwater. Compared to other underwater optical measurement systems, this system offers distinct advantages, including ease of adaptation to a variety of teste, no requirement to be near tank windows, and a simplified rigging system. The system was recently sued to successfully conduct a wavenumber frequency evaluation of the vibratory response of a submerged cylindrical shell. The technical issues in developing the housing and assuring the integrity of the SLV accuracy during transition to underwater use will be discussed. Also, problems encountered in maximizing return signal strength, preparation of the shell, and the process of on-sight data transfer for quick-look wavenumber-frequency analysis while data are being acquired will be presented. The cylindrical shell was excited with 100 to 5000 Hz chirp signals by a 44 N shaker that was attached axially at the center of a bulkhead. A scan consisted of 3 columns with 64 measurement points per column. The shell was rotated 11.25 degrees and the scan repeated to collect an array of 32 by 64 equally spaced points totalling 6144 measurements. The time of data acquisition was about 11 hours. This underwater housing permitted the type of measurements that are not readily available with other systems. With most other techniques the collection time would have been significantly longer. The transfer functions between the velocities measured at each scan location and the shaker force signal were computed as functions of frequency. The transfer functions computed for the center scan columns were then transformed into the wavevector domain using a 2D FFT program. Preliminary results show that the shell response is concentrated near zero circumferential wavenumber, due to the axial symmetry of the driving force. Further, the maximum shell response is also concentrated near the ring frequency of the cylinder, at an axial wavenumber of about -20 rad/m.

Evaluation of interobserver variability of parenchymal phase of Tc-99m mercaptoacetyltriglycine and Tc-99m dimercaptosuccinic acid renal scintigraphy

PubMed Central

Erdoğan, Zeynep; Abdülrezzak, Ümmühan; Silov, Güler; Özdal, Ayşegül; Turhal, Özgül

2014-01-01

Objective: The aim of this study was to investigate the variability in the interpretation of parenchymal abnormalities and to assess the differences in interpretation of routine renal scintigraphic findings on posterior view of technetium-99m dimercaptosuccinic acid (pvDMSA) scans and parenchymal phase of technetium-99m mercaptoacetyltriglycine (ppMAG3) scans by using standard criterions to make standardization and semiquantitative evaluation and to have more accurately correlation. Materials and Methods: Two experienced nuclear medicine physicians independently interpreted pvDMSA scans of 204 and ppMAG3 scans of 102 pediatric patients, retrospectively. Comparisons were made by visual inspection of pvDMSA scans, and ppMAG3 scans by using a grading system modified from Itoh et al. According to this, anatomical damage of the renal parenchyma was classified into six types: Grade 0-V. In the calculation of the agreement rates, Kendall correlation (tau-b) analysis was used. Results: According to our findings, excellent agreement was found for DMSA grade readings (DMSA-GR) (tau-b = 0.827) and good agreement for MAG3 grade readings (MAG3-GR) (tau-b = 0.790) between two observers. Most of clear parenchymal lesions detected on pvDMSA scans and ppMAG3 scans identified by observers equally. Studies with negative or minimal lesions reduced correlation degrees for both DMSA-GR and MAG3-GR. Conclusion: Our grading system can be used for standardization of the reports. We conclude that standardization of criteria and terminology in the interpretations may result in higher interobserver consistency, also improve low interobserver reproducibility and objectivity of renal scintigraphy reports. PMID:24761059

Combined optical resolution photoacoustic and fluorescence micro-endoscopy

NASA Astrophysics Data System (ADS)

Shao, Peng; Shi, Wei; Hajireza, Parsin; Zemp, Roger J.

2012-02-01

We present a new micro-endoscopy system combining real-time C-scan optical-resolution photoacoustic micro-endoscopy (OR-PAME), and a high-resolution fluorescence micro-endoscopy system for visualizing fluorescently labeled cellular components and optically absorbing microvasculature simultaneously. With a diode-pumped 532-nm fiber laser, the OR-PAM sub-system is capable of imaging with a resolution of ~ 7μm. The fluorescence sub-system consists of a diode laser with 445 nm-centered emissions as the light source, an objective lens and a CCD camera. Proflavine, a FDA approved drug for human use, is used as the fluorescent contrast agent by topical application. The fluorescence system does not require any mechanical scanning. The scanning laser and the diode laser light source share the same light path within an optical fiber bundle containing 30,000 individual single mode fibers. The absorption of Proflavine at 532 nm is low, which mitigates absorption bleaching of the contrast agent by the photoacoustic excitation source. We demonstrate imaging in live murine models. The system is able to provide cellular morphology with cellular resolution co-registered with the structural and functional information given by OR-PAM. Therefore, the system has the potential to serve as a virtual biopsy technique, helping researchers and clinicians visualize angiogenesis, effects of anti-cancer drugs on both cells and the microcirculation, as well as aid in the study of other diseases.

Application of Replica Technique and SEM in Accuracy Measurement of Ceramic Crowns

NASA Astrophysics Data System (ADS)

Trifkovic, B.; Budak, I.; Todorovic, A.; Hodolic, J.; Puskar, T.; Jevremovic, D.; Vukelic, D.

2012-01-01

The paper presents a comparative study of the measuring values of the marginal gap related to the ceramic crowns made by dental CAD/CAM system using the replica technique and SEM. The study was conducted using three experimental groups, which consisted of ceramic crowns manufactured by the Cerec CAD/CAM system. The scanning procedure was carried out using three specialized dental 3D digitization systems from the Cerec family - two types of extraoral optical scanning systems and an intraoral optical scanner. Measurements of the marginal gap were carried out using the replica technique and SEM. The comparison of aggregate values of the marginal gap using the replica technique showed a statistically significant difference between the systems. The measured values of marginal gaps of ceramic crowns using the replica technique were significantly lower compared to those measured by SEM. The results indicate that the choice of technique for measuring the accuracy of ceramic crowns influences the final results of investigation.

Cotton phenotyping with lidar from a track-mounted platform

NASA Astrophysics Data System (ADS)

French, Andrew N.; Gore, Michael A.; Thompson, Alison

2016-05-01

High-Throughput Phenotyping (HTP) is a discipline for rapidly identifying plant architectural and physiological responses to environmental factors such as heat and water stress. Experiments conducted since 2010 at Maricopa, Arizona with a three-fold sensor group, including thermal infrared radiometers, active visible/near infrared reflectance sensors, and acoustic plant height sensors, have shown the validity of HTP with a tractor-based system. However, results from these experiments also show that accuracy of plant phenotyping is limited by the system's inability to discriminate plant components and their local environmental conditions. This limitation may be overcome with plant imaging and laser scanning which can help map details in plant architecture and sunlit/shaded leaves. To test the capability for mapping cotton plants with a laser system, a track-mounted platform was deployed in 2015 over a full canopy and defoliated cotton crop consisting of a scanning LIDAR driven by Arduinocontrolled stepper motors. Using custom Python and Tkinter code, the platform moved autonomously along a pipe-track at 0.1 m/s while collecting LIDAR scans at 25 Hz (0.1667 deg. beam). These tests showed that an autonomous LIDAR platform can reduce HTP logistical problems and provide the capability to accurately map cotton plants and cotton bolls. A prototype track-mounted platform was developed to test the use of LIDAR scanning for High- Throughput Phenotyping (HTP). The platform was deployed in 2015 at Maricopa, Arizona over a senescent cotton crop. Using custom Python and Tkinter code, the platform moved autonomously along a pipe-track at <1 m/s while collecting LIDAR scans at 25 Hz (0.1667 deg. beam). Scanning data mapped the canopy heights and widths, and detected cotton bolls.

Application of 3D laser scanning technology in historical building preservation: a case study of a Chinese temple

NASA Astrophysics Data System (ADS)

Chang, Yu Min; Lu, Nien Hua; Wu, Tsung Chiang

2005-06-01

This study applies 3D Laser scanning technology to develop a high-precision measuring system for digital survey of historical building. It outperformed other methods in obtaining abundant high-precision measuring points and computing data instantly. In this study, the Pei-tien Temple, a Chinese Taoism temple in southern Taiwan famous for its highly intricate architecture and more than 300-year history, was adopted as the target to proof the high accuracy and efficiency of this system. By using French made MENSI GS-100 Laser Scanner, numerous measuring points were precisely plotted to present the plane map, vertical map and 3D map of the property. Accuracies of 0.1-1 mm in the digital data have consistently been achieved for the historical heritage measurement.

Centroid Detector Assembly for the AXAF-I Alignment Test System

NASA Technical Reports Server (NTRS)

Glenn, Paul

1995-01-01

The High Resolution Mirror Assembly (HRMA) of the Advanced X-ray Astrophysics Facility (imaging) (AXAF-I) consists of four nested paraboloids and four nested hyperboloids, all of meter-class size, and all of which are to be assembled and aligned in a special 15 meter tower at Eastman Kodak Company in Rochester, NY. The goals of the alignment are (1) to make the images of the four telescopes coincident; (2) to remove coma from each image individually; and (3) to control and determine the final position of the composite focus. This will be accomplished by the HRMA Aligment Test System (HATS) which is essentially a scanning Hartmann test system. The scanning laser source and the focal plane of the HATS are part of the Centroid Detector Assembly (CDA) which also includes processing electronics and software. In this paper we discuss the design and the measured performance of the CDA.

Development of pulse-echo ultrasonic propagation imaging system and its delivery to Korea Air Force

NASA Astrophysics Data System (ADS)

Ahmed, Hasan; Hong, Seung-Chan; Lee, Jung-Ryul; Park, Jongwoon; Ihn, Jeong-Beom

2017-04-01

This paper proposes a full-field pulse-echo ultrasonic propagation imaging (FF-PE-UPI) system for non-destructive evaluation of structural defects. The system works by detection of bulk waves that travel through the thickness of a specimen. This is achieved by joining the laser beams for the ultrasonic wave generation and sensing. This enables accurate and clear damage assessment and defect localization in the thickness with minimum signal processing since bulk waves are less susceptible to dispersion during short propagation through the thickness. The system consists of a Qswitched laser for generating the aforementioned waves, a laser Doppler vibrometer (LDV) for sensing, optical elements to combine the generating and sensing laser beams, a dual-axis automated translation stage for raster scanning of the specimen and a digitizer to record the signals. A graphical user interface (GUI) is developed to control all the individual blocks of the system. Additionally, the software also manages signal acquisition, processing, and display. The GUI is created in C++ using the QT framework. In view of the requirements posed by the Korean Air Force(KAF), the system is designed to be compact and portable to allow for in situ inspection of a selected area of a larger structure such as radome or rudder of an aircraft. The GUI is designed with a minimalistic approach to promote usability and adaptability while masking the intricacies of actual system operation. Through the use of multithreading the software is able to show the results while a specimen is still being scanned. This is achieved by real-time and concurrent acquisition, processing, and display of ultrasonic signal of the latest scan point in the scan area.

Regional variation in the severity of pesticide exposure outcomes: applications of geographic information systems and spatial scan statistics.

PubMed

Sudakin, Daniel L; Power, Laura E

2009-03-01

Geographic information systems and spatial scan statistics have been utilized to assess regional clustering of symptomatic pesticide exposures reported to a state Poison Control Center (PCC) during a single year. In the present study, we analyzed five subsequent years of PCC data to test whether there are significant geographic differences in pesticide exposure incidents resulting in serious (moderate, major, and fatal) medical outcomes. A PCC provided the data on unintentional pesticide exposures for the time period 2001-2005. The geographic location of the caller, the location where the exposure occurred, the exposure route, and the medical outcome were abstracted. There were 273 incidents resulting in moderate effects (n = 261), major effects (n = 10), or fatalities (n = 2). Spatial scan statistics identified a geographic area consisting of two adjacent counties (one urban, one rural), where statistically significant clustering of serious outcomes was observed. The relative risk of moderate, major, and fatal outcomes was 2.0 in this spatial cluster (p = 0.0005). PCC data, geographic information systems, and spatial scan statistics can identify clustering of serious outcomes from human exposure to pesticides. These analyses may be useful for public health officials to target preventive interventions. Further investigation is warranted to understand better the potential explanations for geographical clustering, and to assess whether preventive interventions have an impact on reducing pesticide exposure incidents resulting in serious medical outcomes.

Usability of a real-time tracked augmented reality display system in musculoskeletal injections

NASA Astrophysics Data System (ADS)

Baum, Zachary; Ungi, Tamas; Lasso, Andras; Fichtinger, Gabor

2017-03-01

PURPOSE: Image-guided needle interventions are seldom performed with augmented reality guidance in clinical practice due to many workspace and usability restrictions. We propose a real-time optically tracked image overlay system to make image-guided musculoskeletal injections more efficient and assess its usability in a bed-side clinical environment. METHODS: An image overlay system consisting of an optically tracked viewbox, tablet computer, and semitransparent mirror allows users to navigate scanned patient volumetric images in real-time using software built on the open-source 3D Slicer application platform. A series of experiments were conducted to evaluate the latency and screen refresh rate of the system using different image resolutions. To assess the usability of the system and software, five medical professionals were asked to navigate patient images while using the overlay and completed a questionnaire to assess the system. RESULTS: In assessing the latency of the system with scanned images of varying size, screen refresh rates were approximately 5 FPS. The study showed that participants found using the image overlay system easy, and found the table-mounted system was significantly more usable and effective than the handheld system. CONCLUSION: It was determined that the system performs comparably with scanned images of varying size when assessing the latency of the system. During our usability study, participants preferred the table-mounted system over the handheld. The participants also felt that the system itself was simple to use and understand. With these results, the image overlay system shows promise for use in a clinical environment.

In vivo imaging of the Drosophila Melanogaster heart using a novel optical coherence tomography microscope

NASA Astrophysics Data System (ADS)

Izatt, Susan D.; Choma, Michael A.; Israel, Steven; Wessells, Robert J.; Bodmer, Rolf; Izatt, Joseph A.

2005-03-01

Real time in vivo optical coherence tomography (OCT) imaging of the adult fruit fly Drosophila melanogaster heart using a newly designed OCT microscope allows accurate assessment of cardiac anatomy and function. D. melanogaster has been used extensively in genetic research for over a century, but in vivo evaluation of the heart has been limited by available imaging technology. The ability to assess phenotypic changes with micrometer-scale resolution noninvasively in genetic models such as D. melanogaster is needed in the advancing fields of developmental biology and genetics. We have developed a dedicated small animal OCT imaging system incorporating a state-of-the-art, real time OCT scanner integrated into a standard stereo zoom microscope which allows for simultaneous OCT and video imaging. System capabilities include A-scan, B-scan, and M-scan imaging as well as automated 3D volumetric acquisition and visualization. Transverse and sagittal B-mode scans of the four chambered D. melanogaster heart have been obtained with the OCT microscope and are consistent with detailed anatomical studies from the literature. Further analysis by M-mode scanning is currently under way to assess cardiac function as a function of age and sex by determination of shortening fraction and ejection fraction. These studies create control cardiac data on the wild type D. melanogaster, allowing subsequent evaluation of phenotypic cardiac changes in this model after regulated genetic mutation.

Helicopter pilot scan techniques during low-altitude high-speed flight.

PubMed

Kirby, Christopher E; Kennedy, Quinn; Yang, Ji Hyun

2014-07-01

This study examined pilots' visual scan patterns during a simulated high-speed, low-level flight and how their scan rates related to flight performance. As helicopters become faster and more agile, pilots are expected to navigate at low altitudes while traveling at high speeds. A pilot's ability to interpret information from a combination of visual sources determines not only mission success, but also aircraft and crew survival. In a fixed-base helicopter simulator modeled after the U.S. Navy's MH-60S, 17 active-duty Navy helicopter pilots with varying total flight times flew and navigated through a simulated southern Californian desert course. Pilots' scan rate and fixation locations were monitored using an eye-tracking system while they flew through the course. Flight parameters, including altitude, were recorded using the simulator's recording system. Experienced pilots with more than 1000 total flight hours better maintained a constant altitude (mean altitude deviation = 48.52 ft, SD = 31.78) than less experienced pilots (mean altitude deviation = 73.03 ft, SD = 10.61) and differed in some aspects of their visual scans. They spent more time looking at the instrument display and less time looking out the window (OTW) than less experienced pilots. Looking OTW was associated with less consistency in maintaining altitude. Results may aid training effectiveness specific to helicopter aviation, particularly in high-speed low-level flight conditions.

Using Side-scan Sonar to Characterize and Map Physical Habitat and Anthropogenic Underwater Features in the St. Louis River. (poster)

EPA Science Inventory

Characterizing underwater habitat and other features is difficult and costly, especially in large river systems. The St. Louis River is the largest US tributary to Lake Superior and the lower portion consists of a 48.5 km2 complex of wetlands, tributaries, and bays. We surveyed 8...

A Systems Approach to the Design and Operation of Effective Marketing Programs in Community Colleges.

ERIC Educational Resources Information Center

Scigliano, John A.

1983-01-01

Presents a research-based marketing model consisting of an environmental scanning process, a series of marketing audits, and an information-processing scheme. Views the essential elements of college marketing as information flow; high-level, long-term commitment; diverse strategies; innovation; and a broad view of marketing. Includes a marketing…

Using side-scan sonar to characterize and map physical habitat and anthropogenic underwater features in the St. Louis River

EPA Science Inventory

Characterizing underwater habitat and other features is difficult and costly, especially in large river systems. The St. Louis River is the largest US tributary to Lake Superior and the lower portion consists of a 48.5 km2 complex of wetlands, tributaries, and bays. We surveyed 8...

Bed-sediment grain-size and morphologic data from Suisun, Grizzly, and Honker Bays, CA, 1998-2002

USGS Publications Warehouse

Hampton, Margaret A.; Snyder, Noah P.; Chin, John L.; Allison, Dan W.; Rubin, David M.

2003-01-01

The USGS Place Based Studies Program for San Francisco Bay investigates this sensitive estuarine system to aid in resource management. As part of the inter-disciplinary research program, the USGS collected side-scan sonar data and bed-sediment samples from north San Francisco Bay to characterize bed-sediment texture and investigate temporal trends in sedimentation. The study area is located in central California and consists of Suisun Bay, and Grizzly and Honker Bays, sub-embayments of Suisun Bay. During the study (1998-2002), the USGS collected three side-scan sonar data sets and approximately 300 sediment samples. The side-scan data revealed predominantly fine-grained material on the bayfloor. We also mapped five different bottom types from the data set, categorized as featureless, furrows, sand waves, machine-made, and miscellaneous. We performed detailed grain-size and statistical analyses on the sediment samples. Overall, we found that grain size ranged from clay to fine sand, with the coarsest material in the channels and finer material located in the shallow bays. Grain-size analyses revealed high spatial variability in size distributions in the channel areas. In contrast, the shallow regions exhibited low spatial variability and consistent sediment size over time.

Integrated micro-endoscopy system for simultaneous fluorescence and optical-resolution photoacoustic imaging.

PubMed

Shao, Peng; Shi, Wei; Hajireza, Parsin; Zemp, Roger J

2012-07-01

We present a new integrated micro-endoscopy system combining label-free, fiber-based, real-time C-scan optical-resolution photoacoustic microscopy (F-OR-PAM) and a high-resolution fluorescence micro-endoscopy system for visualizing fluorescently labeled cellular components and optically absorbing microvasculature simultaneously. With a diode-pumped 532-nm fiber laser, the F-OR-PAM sub-system is able to reach a resolution of ∼7  μm. The fluorescence subsystem, which does not require any mechanical scanning, consists of a 447.5-nm-centered diode laser as the light source, an objective lens, and a CCD camera. Proflavine is used as the fluorescent contrast agent by topical application. The scanning laser and the diode laser light source share the same light path within an optical fiber bundle containing 30,000 individual single-mode fibers. The absorption of proflavine at 532 nm is low, which mitigates absorption bleaching of the contrast agent by the photoacoustic excitation source. We demonstrate imaging in live murine models. The system is able to provide cellular morphology with cellular resolution co-registered with the structural information given by F-OR-PAM. Therefore, the system has the potential to serve as a virtual biopsy technique, helping visualize angiogenesis and the effects of anti-cancer drugs on both cells and the microcirculation, as well as aid in the study of other diseases.

Integrated micro-endoscopy system for simultaneous fluorescence and optical-resolution photoacoustic imaging

NASA Astrophysics Data System (ADS)

Shao, Peng; Shi, Wei; Hajireza, Parsin; Zemp, Roger J.

2012-07-01

We present a new integrated micro-endoscopy system combining label-free, fiber-based, real-time C-scan optical-resolution photoacoustic microscopy (F-OR-PAM) and a high-resolution fluorescence micro-endoscopy system for visualizing fluorescently labeled cellular components and optically absorbing microvasculature simultaneously. With a diode-pumped 532-nm fiber laser, the F-OR-PAM sub-system is able to reach a resolution of ~7 μm. The fluorescence subsystem, which does not require any mechanical scanning, consists of a 447.5-nm-centered diode laser as the light source, an objective lens, and a CCD camera. Proflavine is used as the fluorescent contrast agent by topical application. The scanning laser and the diode laser light source share the same light path within an optical fiber bundle containing 30,000 individual single-mode fibers. The absorption of proflavine at 532 nm is low, which mitigates absorption bleaching of the contrast agent by the photoacoustic excitation source. We demonstrate imaging in live murine models. The system is able to provide cellular morphology with cellular resolution co-registered with the structural information given by F-OR-PAM. Therefore, the system has the potential to serve as a virtual biopsy technique, helping visualize angiogenesis and the effects of anti-cancer drugs on both cells and the microcirculation, as well as aid in the study of other diseases.

SU-F-T-160: Commissioning of a Single-Room Double-Scattering Proton Therapy System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin, H; Ahmad, S; Chen, Y

2016-06-15

Purpose: To report the detailed commissioning experience for a compact double-scattering Mevion S250 proton therapy system at a University Cancer Center site. Methods: The commissioning of the proton therapy system mainly consisted of ensuring integrity of mechanical and imaging system, beam data collection, and commissioning of a treatment planning system (TPS). First, mechanical alignment and imaging were tested including safety, interlocks, positional accuracy of couch and gantry, image quality, mechanical and imaging isocenter and so on. Second, extensive beam data (outputs, PDDs, and profiles) were collected and analyzed through effective sampling of range (R) and modulation width (M) from 24more » beam options. Three different output (cGy/MU) prediction models were also commissioned as primary and secondary MU calculation tool. Third, the Varian Eclipse TPS was commissioned through five sets of data collections (in-water Bragg peak scans, in-air longitudinal fluence scans, in-air lateral profiles, in-air half-beam profiles, and an HU-to-stopping-power conversion curve) and accuracy of TPS calculation was tested using in-water scans and dose measurements with a 2D array detector with block and range compensator. Finally, an anthropomorphic phantom was scanned and heterogeneity effects were tested by inserting radiochromic films in the phantom and PET activation scans for range verification in conjunction with end-to-end test. Results: Beam characteristics agreed well with the vendor specifications; however, minor mismatches in R and M were found in some measurements during the beam data collection. These were reflected into the TPS commissioning such that the TPS could accurately predict the R and M within tolerance levels. The output models had a good agreement with measured outputs (<3% error). The end-to-end test using the film and PET showed reasonably the TPS predicted dose, R and M in heterogeneous medium. Conclusion: The proton therapy system was successfully commissioned and was released for clinical use.« less

Correlative imaging of biological tissues with apertureless scanning near-field optical microscopy and confocal laser scanning microscopy

PubMed Central

Stanciu, Stefan G.; Tranca, Denis E.; Hristu, Radu; Stanciu, George A.

2017-01-01

Apertureless scanning near-field optical microscopy (ASNOM) has attracted considerable interest over the past years as a result of its valuable contrast mechanisms and capabilities for optical resolutions in the nanoscale range. However, at this moment the intersections between ASNOM and the realm of bioimaging are scarce, mainly due to data interpretation difficulties linked to the limited body of work performed so far in this field and hence the reduced volume of supporting information. We propose an imaging approach that holds significant potential for alleviating this issue, consisting of correlative imaging of biological specimens using a multimodal system that incorporates ASNOM and confocal laser scanning microscopy (CLSM), which allows placing near-field data into a well understood context of anatomical relevance. We demonstrate this approach on zebrafish retinal tissue. The proposed method holds important implications for the in-depth understanding of biological items through the prism of ASNOM and CLSM data complementarity. PMID:29296474

Portable Handheld Optical Window Inspection Device

NASA Technical Reports Server (NTRS)

Ihlefeld, Curtis; Dokos, Adam; Burns, Bradley

2010-01-01

The Portable Handheld Optical Window Inspection Device (PHOWID) is a measurement system for imaging small defects (scratches, pits, micrometeor impacts, and the like) in the field. Designed primarily for window inspection, PHOWID attaches to a smooth surface with suction cups, and raster scans a small area with an optical pen in order to provide a three-dimensional image of the defect. PHOWID consists of a graphical user interface, motor control subsystem, scanning head, and interface electronics, as well as an integrated camera and user display that allows a user to locate minute defects before scanning. Noise levels are on the order of 60 in. (1.5 m). PHOWID allows field measurement of defects that are usually done in the lab. It is small, light, and attaches directly to the test article in any orientation up to vertical. An operator can scan a defect and get useful engineering data in a matter of minutes. There is no need to make a mold impression for later lab analysis.

Local dynamic range compensation for scanning electron microscope imaging system by sub-blocking multiple peak HE with convolution.

PubMed

Sim, K S; Teh, V; Tey, Y C; Kho, T K

2016-11-01

This paper introduces new development technique to improve the Scanning Electron Microscope (SEM) image quality and we name it as sub-blocking multiple peak histogram equalization (SUB-B-MPHE) with convolution operator. By using this new proposed technique, it shows that the new modified MPHE performs better than original MPHE. In addition, the sub-blocking method consists of convolution operator which can help to remove the blocking effect for SEM images after applying this new developed technique. Hence, by using the convolution operator, it effectively removes the blocking effect by properly distributing the suitable pixel value for the whole image. Overall, the SUB-B-MPHE with convolution outperforms the rest of methods. SCANNING 38:492-501, 2016. © 2015 Wiley Periodicals, Inc. © Wiley Periodicals, Inc.

Macroscopic model of scanning force microscope

DOEpatents

Guerra-Vela, Claudio; Zypman, Fredy R.

2004-10-05

A macroscopic version of the Scanning Force Microscope is described. It consists of a cantilever under the influence of external forces, which mimic the tip-sample interactions. The use of this piece of equipment is threefold. First, it serves as direct way to understand the parts and functions of the Scanning Force Microscope, and thus it is effectively used as an instructional tool. Second, due to its large size, it allows for simple measurements of applied forces and parameters that define the state of motion of the system. This information, in turn, serves to compare the interaction forces with the reconstructed ones, which cannot be done directly with the standard microscopic set up. Third, it provides a kinematics method to non-destructively measure elastic constants of materials, such as Young's and shear modules, with special application for brittle materials.

A new linear structured light module based on the MEMS micromirror

NASA Astrophysics Data System (ADS)

Zhou, Peng; Shen, Wenjiang; Yu, Huijun

2017-10-01

A new linear structured light module based on the Micro-Electro-Mechanical System (MEMS) two-dimensional scanning micromirror was designed and created. This module consists of a laser diode, a convex lens, and the MEMS micromirror. The laser diode generates the light and the convex lens control the laser beam to converge on a single point with large depth of focus. The fast scan in horizontal direction of the micromirror will turn the laser spot into a homogenous laser line. Meanwhile, the slow scan in vertical direction of the micromirror will move the laser line in the vertical direction. The width of the line generated by this module is 300μm and the length is 120mm and the moving distance is 100mm at 30cm away from the module. It will promote the development of industrial detection.

Acquisition of multiple image stacks with a confocal laser scanning microscope

NASA Astrophysics Data System (ADS)

Zuschratter, Werner; Steffen, Thomas; Braun, Katharina; Herzog, Andreas; Michaelis, Bernd; Scheich, Henning

1998-06-01

Image acquisition at high magnification is inevitably correlated with a limited view over the entire tissue section. To overcome this limitation we designed software for multiple image-stack acquisition (3D-MISA) in confocal laser scanning microscopy (CLSM). The system consists of a 4 channel Leica CLSM equipped with a high resolution z- scanning stage mounted on a xy-monitorized stage. The 3D- MISA software is implemented into the microscope scanning software and uses the microscope settings for the movements of the xy-stage. It allows storage and recall of 70 xyz- positions and the automatic 3D-scanning of image arrays between selected xyz-coordinates. The number of images within one array is limited only by the amount of disk space or memory available. Although for most applications the accuracy of the xy-scanning stage is sufficient for a precise alignment of tiled views, the software provides the possibility of an adjustable overlap between two image stacks by shifting the moving steps of the xy-scanning stage. After scanning a tiled image gallery of the extended focus-images of each channel will be displayed on a graphic monitor. In addition, a tiled image gallery of individual focal planes can be created. In summary, the 3D-MISA allows 3D-image acquisition of coherent regions in combination with high resolution of single images.

High-speed photon-counting x-ray computed tomography system utilizing a multipixel photon counter

NASA Astrophysics Data System (ADS)

Sato, Eiichi; Enomoto, Toshiyuki; Watanabe, Manabu; Hitomi, Keitaro; Takahashi, Kiyomi; Sato, Shigehiro; Ogawa, Akiro; Onagawa, Jun

2009-07-01

High-speed photon counting is useful for discriminating photon energy and for decreasing absorbed dose for patients in medical radiography, and the counting is usable for constructing an x-ray computed tomography (CT) system. A photon-counting x-ray CT system is of the first generation type and consists of an x-ray generator, a turn table, a translation stage, a two-stage controller, a multipixel photon counter (MPPC) module, a 1.0-mm-thick LSO crystal (scintillator), a counter card (CC), and a personal computer (PC). Tomography is accomplished by repeating the linear scanning and the rotation of an object, and projection curves of the object are obtained by the linear scanning using the detector consisting of a MPPC module and the LSO. The pulses of the event signal from the module are counted by the CC in conjunction with the PC. The lower level of the photon energy is roughly determined by a comparator circuit in the module, and the unit of the level is the photon equivalent (pe). Thus, the average photon energy of the x-ray spectra increases with increasing the lower-level voltage of the comparator. The maximum count rate was approximately 20 Mcps, and energy-discriminated CT was roughly carried out.

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s.

PubMed

Wieser, Wolfgang; Draxinger, Wolfgang; Klein, Thomas; Karpf, Sebastian; Pfeiffer, Tom; Huber, Robert

2014-09-01

We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin.

High definition live 3D-OCT in vivo: design and evaluation of a 4D OCT engine with 1 GVoxel/s

PubMed Central

Wieser, Wolfgang; Draxinger, Wolfgang; Klein, Thomas; Karpf, Sebastian; Pfeiffer, Tom; Huber, Robert

2014-01-01

We present a 1300 nm OCT system for volumetric real-time live OCT acquisition and visualization at 1 billion volume elements per second. All technological challenges and problems associated with such high scanning speed are discussed in detail as well as the solutions. In one configuration, the system acquires, processes and visualizes 26 volumes per second where each volume consists of 320 x 320 depth scans and each depth scan has 400 usable pixels. This is the fastest real-time OCT to date in terms of voxel rate. A 51 Hz volume rate is realized with half the frame number. In both configurations the speed can be sustained indefinitely. The OCT system uses a 1310 nm Fourier domain mode locked (FDML) laser operated at 3.2 MHz sweep rate. Data acquisition is performed with two dedicated digitizer cards, each running at 2.5 GS/s, hosted in a single desktop computer. Live real-time data processing and visualization are realized with custom developed software on an NVidia GTX 690 dual graphics processing unit (GPU) card. To evaluate potential future applications of such a system, we present volumetric videos captured at 26 and 51 Hz of planktonic crustaceans and skin. PMID:25401010

Automated Guided-Wave Scanning Developed to Characterize Materials and Detect Defects

NASA Technical Reports Server (NTRS)

Martin, Richard E.; Gyekenyeski, Andrew L.; Roth, Don J.

2004-01-01

The Nondestructive Evaluation (NDE) Group of the Optical Instrumentation Technology Branch at the NASA Glenn Research Center has developed a scanning system that uses guided waves to characterize materials and detect defects. The technique uses two ultrasonic transducers to interrogate the condition of a material. The sending transducer introduces an ultrasonic pulse at a point on the surface of the specimen, and the receiving transducer detects the signal after it has passed through the material. The aim of the method is to correlate certain parameters in both the time and frequency domains of the detected waveform to characteristics of the material between the two transducers. The scanning system is shown. The waveform parameters of interest include the attenuation due to internal damping, waveform shape parameters, and frequency shifts due to material changes. For the most part, guided waves are used to gauge the damage state and defect growth of materials subjected to various mechanical or environmental loads. The technique has been applied to polymer matrix composites, ceramic matrix composites, and metal matrix composites as well as metallic alloys. Historically, guided wave analysis has been a point-by-point, manual technique with waveforms collected at discrete locations and postprocessed. Data collection and analysis of this type limits the amount of detail that can be obtained. Also, the manual movement of the sensors is prone to user error and is time consuming. The development of an automated guided-wave scanning system has allowed the method to be applied to a wide variety of materials in a consistent, repeatable manner. Experimental studies have been conducted to determine the repeatability of the system as well as compare the results obtained using more traditional NDE methods. The following screen capture shows guided-wave scan results for a ceramic matrix composite plate, including images for each of nine calculated parameters. The system can display up to 18 different wave parameters. Multiple scans of the test specimen demonstrated excellent repeatability in the measurement of all the guided-wave parameters, far exceeding the traditional point-by-point technique. In addition, the scan was able to detect a subsurface defect that was confirmed using flash thermography This technology is being further refined to provide a more robust and efficient software environment. Future hardware upgrades will allow for multiple receiving transducers and the ability to scan more complex surfaces. This work supports composite materials development and testing under the Ultra-Efficient Engine Technology (UEET) Project, but it also will be applied to other material systems under development for a wide range of applications.

A modular designed ultra-high-vacuum spin-polarized scanning tunneling microscope with controllable magnetic fields for investigating epitaxial thin films.

PubMed

Wang, Kangkang; Lin, Wenzhi; Chinchore, Abhijit V; Liu, Yinghao; Smith, Arthur R

2011-05-01

A room-temperature ultra-high-vacuum scanning tunneling microscope for in situ scanning freshly grown epitaxial films has been developed. The core unit of the microscope, which consists of critical components including scanner and approach motors, is modular designed. This enables easy adaptation of the same microscope units to new growth systems with different sample-transfer geometries. Furthermore the core unit is designed to be fully compatible with cryogenic temperatures and high magnetic field operations. A double-stage spring suspension system with eddy current damping has been implemented to achieve ≤5 pm z stability in a noisy environment and in the presence of an interconnected growth chamber. Both tips and samples can be quickly exchanged in situ; also a tunable external magnetic field can be introduced using a transferable permanent magnet shuttle. This allows spin-polarized tunneling with magnetically coated tips. The performance of this microscope is demonstrated by atomic-resolution imaging of surface reconstructions on wide band-gap GaN surfaces and spin-resolved experiments on antiferromagnetic Mn(3)N(2)(010) surfaces.

Analysis of the dynamics and frequency spectrum synthesis of an optical-mechanical scanning device

NASA Technical Reports Server (NTRS)

Andryushkevichyus, A. I.; Kumpikas, A. L.; Kumpikas, K. L.

1973-01-01

A two-coordinate optical-mechanical scanning device (OMSD), the operating unit of which is a scanning disk, with directional and focusing optics and a board, on which the data carrier is placed, is examined. The disk and board are kinematically connected by a transmission mechanism, consisting of a worm and complex gear drive and a tightening screw-nut with correcting device, and it is run by a synchronous type motor. The dynamic errors in the system depend, first, on irregularities in rotation of the disk, fluctuations in its axis and vibrations of the table in the plane parallel to the plane of the disk. The basic sources of the fluctuations referred to above are residual disbalance of the rotor and other rotating masses, the periodic component of the driving torque of the synchronous motor, variability in the resistance, kinematic errors in the drive and other things. The fluctuations can be transmitted to the operating units through the kinematic link as a flexural-torsional system, as well as through vibrations of the housing of the device.

The original method for imaging of biological tissues in optical coherence tomography with usage of hyperchromatic lens

NASA Astrophysics Data System (ADS)

Egorov, D. I.

2017-06-01

Our study focuses on an analysis of the original method of investigation biological tissues in the spectral OCT (optical coherence tomography) with usage hyperchromatic lenses. Using hyperchromatic lens, i.e. the lens with uncorrected longitudinal color allows scanning in the depth of the object by changing the wavelength of the emitter. In this case, the depth of the scan will be determined not by the microlens depth of field, but the value of axial color. In our study, we demonstrated the advantages of this method of research on biological tissues existing. Spectral OCT schemes with the hyperchromatic lens could increase the depth of spectral scanning, eliminate the use of multi-channel systems with a set of microscope objectives, reduce the time of measurement. In our paper, we show the developed method of calculation of hyperchromatic lenses and hybrid hyperchromatic lens consisting of a diffractive and refractive component in spectral OCT systems. We also demonstrate the results of aberration calculation designed microscope lenses. We show examples of developed hyperchromatic lenses with the diffractive element and without it.

Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance

PubMed Central

Cruz-Bastida, Juan P.; Gomez-Cardona, Daniel; Li, Ke; Sun, Heyi; Hsieh, Jiang; Szczykutowicz, Timothy P.; Chen, Guang-Hong

2016-01-01

Purpose: The introduction of a High-Resolution (Hi-Res) scan mode and another associated option that combines Hi-Res mode with the so-called High Definition (HD) reconstruction kernels (referred to as a Hi-Res/HD mode in this paper) in some multi-detector CT (MDCT) systems offers new opportunities to increase spatial resolution for some clinical applications that demand high spatial resolution. The purpose of this work was to quantify the in-plane spatial resolution along both the radial direction and tangential direction for the Hi-Res and Hi-Res/HD scan modes at different off-center positions. Methods: A technique was introduced and validated to address the signal saturation problem encountered in the attempt to quantify spatial resolution for the Hi-Res and Hi-Res/HD scan modes. Using the proposed method, the modulation transfer functions (MTFs) of a 64-slice MDCT system (Discovery CT750 HD, GE Healthcare) equipped with both Hi-Res and Hi-Res/HD modes were measured using a metal bead at nine different off-centered positions (0–16 cm with a step size of 2 cm); at each position, both conventional scans and Hi-Res scans were performed. For each type of scan and position, 80 repeated acquisitions were performed to reduce noise induced uncertainties in the MTF measurements. A total of 15 reconstruction kernels, including eight conventional kernels and seven HD kernels, were used to reconstruct CT images of the bead. An ex vivo animal study consisting of a bone fracture model was performed to corroborate the MTF results, as the detection of this high-contrast and high frequency task is predominantly determined by spatial resolution. Images of this animal model generated by different scan modes and reconstruction kernels were qualitatively compared with the MTF results. Results: At the centered position, the use of Hi-Res mode resulted in a slight improvement in the MTF; each HD kernel generated higher spatial resolution than its counterpart conventional kernel. However, the MTF along the tangential direction of the scan field of view (SFOV) was significantly degraded at off-centered positions, yet the combined Hi-Res/HD mode reduced this azimuthal MTF degradation. Images of the animal bone fracture model confirmed the improved spatial resolution at the off-centered positions through the use of the Hi-Res mode and HD kernels. Conclusions: The Hi-Res/HD scan improve spatial resolution of MDCT systems at both centered and off-centered positions. PMID:27147351

Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance.

PubMed

Cruz-Bastida, Juan P; Gomez-Cardona, Daniel; Li, Ke; Sun, Heyi; Hsieh, Jiang; Szczykutowicz, Timothy P; Chen, Guang-Hong

2016-05-01

The introduction of a High-Resolution (Hi-Res) scan mode and another associated option that combines Hi-Res mode with the so-called High Definition (HD) reconstruction kernels (referred to as a Hi-Res/HD mode in this paper) in some multi-detector CT (MDCT) systems offers new opportunities to increase spatial resolution for some clinical applications that demand high spatial resolution. The purpose of this work was to quantify the in-plane spatial resolution along both the radial direction and tangential direction for the Hi-Res and Hi-Res/HD scan modes at different off-center positions. A technique was introduced and validated to address the signal saturation problem encountered in the attempt to quantify spatial resolution for the Hi-Res and Hi-Res/HD scan modes. Using the proposed method, the modulation transfer functions (MTFs) of a 64-slice MDCT system (Discovery CT750 HD, GE Healthcare) equipped with both Hi-Res and Hi-Res/HD modes were measured using a metal bead at nine different off-centered positions (0-16 cm with a step size of 2 cm); at each position, both conventional scans and Hi-Res scans were performed. For each type of scan and position, 80 repeated acquisitions were performed to reduce noise induced uncertainties in the MTF measurements. A total of 15 reconstruction kernels, including eight conventional kernels and seven HD kernels, were used to reconstruct CT images of the bead. An ex vivo animal study consisting of a bone fracture model was performed to corroborate the MTF results, as the detection of this high-contrast and high frequency task is predominantly determined by spatial resolution. Images of this animal model generated by different scan modes and reconstruction kernels were qualitatively compared with the MTF results. At the centered position, the use of Hi-Res mode resulted in a slight improvement in the MTF; each HD kernel generated higher spatial resolution than its counterpart conventional kernel. However, the MTF along the tangential direction of the scan field of view (SFOV) was significantly degraded at off-centered positions, yet the combined Hi-Res/HD mode reduced this azimuthal MTF degradation. Images of the animal bone fracture model confirmed the improved spatial resolution at the off-centered positions through the use of the Hi-Res mode and HD kernels. The Hi-Res/HD scan improve spatial resolution of MDCT systems at both centered and off-centered positions.

Model-Based Angular Scan Error Correction of an Electrothermally-Actuated MEMS Mirror

PubMed Central

Zhang, Hao; Xu, Dacheng; Zhang, Xiaoyang; Chen, Qiao; Xie, Huikai; Li, Suiqiong

2015-01-01

In this paper, the actuation behavior of a two-axis electrothermal MEMS (Microelectromechanical Systems) mirror typically used in miniature optical scanning probes and optical switches is investigated. The MEMS mirror consists of four thermal bimorph actuators symmetrically located at the four sides of a central mirror plate. Experiments show that an actuation characteristics difference of as much as 4.0% exists among the four actuators due to process variations, which leads to an average angular scan error of 0.03°. A mathematical model between the actuator input voltage and the mirror-plate position has been developed to predict the actuation behavior of the mirror. It is a four-input, four-output model that takes into account the thermal-mechanical coupling and the differences among the four actuators; the vertical positions of the ends of the four actuators are also monitored. Based on this model, an open-loop control method is established to achieve accurate angular scanning. This model-based open loop control has been experimentally verified and is useful for the accurate control of the mirror. With this control method, the precise actuation of the mirror solely depends on the model prediction and does not need the real-time mirror position monitoring and feedback, greatly simplifying the MEMS control system. PMID:26690432

Computer-aided screening system for cervical precancerous cells based on field emission scanning electron microscopy and energy dispersive x-ray images and spectra

NASA Astrophysics Data System (ADS)

Jusman, Yessi; Ng, Siew-Cheok; Hasikin, Khairunnisa; Kurnia, Rahmadi; Osman, Noor Azuan Bin Abu; Teoh, Kean Hooi

2016-10-01

The capability of field emission scanning electron microscopy and energy dispersive x-ray spectroscopy (FE-SEM/EDX) to scan material structures at the microlevel and characterize the material with its elemental properties has inspired this research, which has developed an FE-SEM/EDX-based cervical cancer screening system. The developed computer-aided screening system consisted of two parts, which were the automatic features of extraction and classification. For the automatic features extraction algorithm, the image and spectra of cervical cells features extraction algorithm for extracting the discriminant features of FE-SEM/EDX data was introduced. The system automatically extracted two types of features based on FE-SEM/EDX images and FE-SEM/EDX spectra. Textural features were extracted from the FE-SEM/EDX image using a gray level co-occurrence matrix technique, while the FE-SEM/EDX spectra features were calculated based on peak heights and corrected area under the peaks using an algorithm. A discriminant analysis technique was employed to predict the cervical precancerous stage into three classes: normal, low-grade intraepithelial squamous lesion (LSIL), and high-grade intraepithelial squamous lesion (HSIL). The capability of the developed screening system was tested using 700 FE-SEM/EDX spectra (300 normal, 200 LSIL, and 200 HSIL cases). The accuracy, sensitivity, and specificity performances were 98.2%, 99.0%, and 98.0%, respectively.

State-of-the-art cockpit design for the HH-65A helicopters

NASA Technical Reports Server (NTRS)

Castleberry, D. E.; Mcelreath, M. Y.

1982-01-01

In the design of a HH-65A helicopter cockpit, advanced integrated electronics systems technology was employed to achieve several important goals for this multimission aircraft. They were: (1) integrated systems operation with consistent and simplified cockpit procedures; (2) mission-task-related cockpit displays and controls, and (3) reduced pilot instrument scan effort with excellent outside visibility. The integrated avionics system was implemented to depend heavily upon distributed but complementary processing, multiplex digital bus technology, and multifunction CRT controls and displays. This avionics system was completely flight tested and will soon enter operational service with the Coast Guard.

CT Scans of NASA BSTRA Balls 5f5, f2, f3, sr2c, nb2a, hb2b

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gross, J; Thompson, R; Perry, R

2004-01-29

At the request of Jose Hernandez we performed some feasibility DR/CT scanning of BSTRA Balls of different sizes. To this point we have scanned all the specimens on a single system, HECAT. This particular system employs a 9 meV LINAC as the x-ray source and a THALES 12 x 16 inch 14-bit Amorphous Silicon panel as the detector. In this report we describe the system, detail some of its properties, describe the scans performed and present the data. Figure 1 contains a couple of images of the system as fielded in the 9 MeV bay. The LINAC is in themore » right portion of the picture. The black panels in the blue frame constitute the High Energy collimator developed specifically for High Energy DR/CT scanning (known here as Stonehenge II). The holes in the collimator panels are beveled to match the distribution of the x-rays from the LINAC, and are sized to just subtend the active area of the THALES Amorphous Silicon panel. Consequently the source to detector distance is restricted to a few positions. Nominally our source to detector distance is 6 meters. The part manipulator, part holder fixturing consists of a translate-rotate assembly on a NEWPORT air bearing table. The stages are NEWPORT RV160PP for rotation and NEWPORT IMS400CC for translation. Both are interfaced through an ESP7000 controller, which is connected to our data acquisition computer over USB. The detector holder also resides on this table and includes pitch, roll and yaw adjustments for aligning the panel to the plane of the rotational table and the x-ray beam. The relatively large source to detector distance and LINAC properties (1 mm spot size) conspire to recommend rotation-only scanning. We use a VARIAN LINATRON 3000 with the small spot retrofit implemented. We have measured the source spot size at about 1 mm. Pixel size on the THALES panel is 0.127 um. Consequently we are in a low-cone angle scanning regime which enables rotation-only 3D CT scanning of objects and assemblies with little ''cone-angle'' error.« less

Molecular diodes based on conjugated diblock co-oligomers.

PubMed

Ng, Man-Kit; Lee, Dong-Chan; Yu, Luping

2002-10-09

This report describes synthesis and characterization of a molecular diode based upon a diblock conjugated oligomer system. This system consists of two conjugated blocks with opposite electronic demand. The molecular structure exhibits a built-in electronic asymmetry, much like a semiconductor p-n junction. Electrical measurements by scanning tunneling spectroscopy (STS) clearly revealed a pronounced rectifying effect. Definitive proof for the molecular nature of the rectifying effect in this conjugated diblock molecule is provided by control experiments with a structurally similar reference compound.

Obstetric audit: the Bradford way.

PubMed

Lodge, Virginia; Lomas, Karen; Jaworskyj, Suzanne; Thomson, Heidi

2014-08-01

Ultrasound is widely used as a screening tool in obstetrics with the aim of reducing maternal and foetal morbidity. However, to be effective it is recommended that scanning services follow standard protocols based on national guidelines and that scanning practice is audited to ensure consistency. Bradford has a multi-ethnic population with one of the highest rates of birth defects in the UK and it requires an effective foetal anomaly screening service. We implemented a rolling programme of audits of dating scans, foetal anomaly scans and growth scans carried out by sonographers in Bradford. All three categories of scan were audited using measurable parameters based on national guidelines. Following feedback and re-training to address issues identified, re-audits of dating and foetal anomaly scans were carried out. In both cases, sonographers being re-audited had a marked improvement in their practice. Analysis of foetal abnormality detection rates showed that as a department, we were reaching the nationally agreed detection rates for the Fetal Anomaly Screening Programme auditable conditions. Audit has been shown to be a useful and essential process in achieving consistent scanning practices and high quality images and measurements.

Obstetric audit: the Bradford way

PubMed Central

Lomas, Karen; Jaworskyj, Suzanne; Thomson, Heidi

2014-01-01

Ultrasound is widely used as a screening tool in obstetrics with the aim of reducing maternal and foetal morbidity. However, to be effective it is recommended that scanning services follow standard protocols based on national guidelines and that scanning practice is audited to ensure consistency. Bradford has a multi-ethnic population with one of the highest rates of birth defects in the UK and it requires an effective foetal anomaly screening service. We implemented a rolling programme of audits of dating scans, foetal anomaly scans and growth scans carried out by sonographers in Bradford. All three categories of scan were audited using measurable parameters based on national guidelines. Following feedback and re-training to address issues identified, re-audits of dating and foetal anomaly scans were carried out. In both cases, sonographers being re-audited had a marked improvement in their practice. Analysis of foetal abnormality detection rates showed that as a department, we were reaching the nationally agreed detection rates for the Fetal Anomaly Screening Programme auditable conditions. Audit has been shown to be a useful and essential process in achieving consistent scanning practices and high quality images and measurements. PMID:27433213

Multi-Mounted X-Ray Computed Tomography.

PubMed

Fu, Jian; Liu, Zhenzhong; Wang, Jingzheng

2016-01-01

Most existing X-ray computed tomography (CT) techniques work in single-mounted mode and need to scan the inspected objects one by one. It is time-consuming and not acceptable for the inspection in a large scale. In this paper, we report a multi-mounted CT method and its first engineering implementation. It consists of a multi-mounted scanning geometry and the corresponding algebraic iterative reconstruction algorithm. This approach permits the CT rotation scanning of multiple objects simultaneously without the increase of penetration thickness and the signal crosstalk. Compared with the conventional single-mounted methods, it has the potential to improve the imaging efficiency and suppress the artifacts from the beam hardening and the scatter. This work comprises a numerical study of the method and its experimental verification using a dataset measured with a developed multi-mounted X-ray CT prototype system. We believe that this technique is of particular interest for pushing the engineering applications of X-ray CT.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paliwal, B; Asprey, W; Yan, Y

Purpose: In order to take advantage of the high resolution soft tissue imaging available in MR images, we investigated 3D images obtained with the low field 0.35 T MR in ViewRay to serve as an alternative to CT scans for radiotherapy treatment planning. In these images, normal and target structure delineation can be visualized. Assessment is based upon comparison with the CT images and the ability to produce comparable contours. Methods: Routine radiation oncology CT scans were acquired on five patients. Contours of brain, brainstem, esophagus, heart, lungs, spinal cord, and the external body were drawn. The same five patientsmore » were then scanned on the ViewRay TrueFISP-based imaging pulse sequence. The same organs were selected on the MR images and compared to those from the CT scan. Physical volume and the Dice Similarity Coefficient (DSC) were used to assess the contours from the two systems. Image quality stability was quantitatively ensured throughout the study following the recommendations of the ACR MR accreditation procedure. Results: The highest DSC of 0.985, 0.863, and 0.843 were observed for brain, lungs, and heart respectively. On the other hand, the brainstem, spinal cord, and esophagus had the lowest DSC. Volume agreement was most satisfied for the heart (within 5%) and the brain (within 2%). Contour volume for the brainstem and lung (a widely dynamic organ) varied the most (27% and 19%). Conclusion: The DSC and volume measurements suggest that the results obtained from ViewRay images are quantitatively consistent and comparable to those obtained from CT scans for the brain, heart, and lungs. MR images from ViewRay are well-suited for treatment planning and for adaptive MRI-guided radiotherapy. The physical data from 0.35 T MR imaging is consistent with our geometrical understanding of normal structures.« less

Tracking scanning laser ophthalmoscope (TSLO)

NASA Astrophysics Data System (ADS)

Hammer, Daniel X.; Ferguson, R. Daniel; Magill, John C.; White, Michael A.; Elsner, Ann E.; Webb, Robert H.

2003-07-01

The effectiveness of image stabilization with a retinal tracker in a multi-function, compact scanning laser ophthalmoscope (TSLO) was demonstrated in initial human subject tests. The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the fundus. The system is modular to allow configuration for many research and clinical applications, including hyperspectral imaging, multifocal electroretinography (MFERG), perimetry, quantification of macular and photo-pigmentation, imaging of neovascularization and other subretinal structures (drusen, hyper-, and hypo-pigmentation), and endogenous fluorescence imaging. Optical hardware features include dual wavelength imaging and detection, integrated monochromator, higher-order motion control, and a stimulus source. The system software consists of a real-time feedback control algorithm and a user interface. Software enhancements include automatic bias correction, asymmetric feature tracking, image averaging, automatic track re-lock, and acquisition and logging of uncompressed images and video files. Normal adult subjects were tested without mydriasis to optimize the tracking instrumentation and to characterize imaging performance. The retinal tracking system achieves a bandwidth of greater than 1 kHz, which permits tracking at rates that greatly exceed the maximum rate of motion of the human eye. The TSLO stabilized images in all test subjects during ordinary saccades up to 500 deg/sec with an inter-frame accuracy better than 0.05 deg. Feature lock was maintained for minutes despite subject eye blinking. Successful frame averaging allowed image acquisition with decreased noise in low-light applications. The retinal tracking system significantly enhances the imaging capabilities of the scanning laser ophthalmoscope.

Automated system for lung nodules classification based on wavelet feature descriptor and support vector machine.

PubMed

Madero Orozco, Hiram; Vergara Villegas, Osslan Osiris; Cruz Sánchez, Vianey Guadalupe; Ochoa Domínguez, Humberto de Jesús; Nandayapa Alfaro, Manuel de Jesús

2015-02-12

Lung cancer is a leading cause of death worldwide; it refers to the uncontrolled growth of abnormal cells in the lung. A computed tomography (CT) scan of the thorax is the most sensitive method for detecting cancerous lung nodules. A lung nodule is a round lesion which can be either non-cancerous or cancerous. In the CT, the lung cancer is observed as round white shadow nodules. The possibility to obtain a manually accurate interpretation from CT scans demands a big effort by the radiologist and might be a fatiguing process. Therefore, the design of a computer-aided diagnosis (CADx) system would be helpful as a second opinion tool. The stages of the proposed CADx are: a supervised extraction of the region of interest to eliminate the shape differences among CT images. The Daubechies db1, db2, and db4 wavelet transforms are computed with one and two levels of decomposition. After that, 19 features are computed from each wavelet sub-band. Then, the sub-band and attribute selection is performed. As a result, 11 features are selected and combined in pairs as inputs to the support vector machine (SVM), which is used to distinguish CT images containing cancerous nodules from those not containing nodules. The clinical data set used for experiments consists of 45 CT scans from ELCAP and LIDC. For the training stage 61 CT images were used (36 with cancerous lung nodules and 25 without lung nodules). The system performance was tested with 45 CT scans (23 CT scans with lung nodules and 22 without nodules), different from that used for training. The results obtained show that the methodology successfully classifies cancerous nodules with a diameter from 2 mm to 30 mm. The total preciseness obtained was 82%; the sensitivity was 90.90%, whereas the specificity was 73.91%. The CADx system presented is competitive with other literature systems in terms of sensitivity. The system reduces the complexity of classification by not performing the typical segmentation stage of most CADx systems. Additionally, the novelty of the algorithm is the use of a wavelet feature descriptor.

Dual Resolution Images from Paired Fingerprint Cards

National Institute of Standards and Technology Data Gateway

NIST Dual Resolution Images from Paired Fingerprint Cards (Web, free access)   NIST Special Database 30 is being distributed for use in development and testing of fingerprint compression and fingerprint matching systems. The database allows the user to develop and evaluate data compression algorithms for fingerprint images scanned at both 19.7 ppmm (500 dpi) and 39.4 ppmm (1000 dpi). The data consist of 36 ten-print paired cards with both the rolled and plain images scanned at 19.7 and 39.4 pixels per mm. A newer version of the compression/decompression software on the CDROM can be found at the website http://www.nist.gov/itl/iad/ig/nigos.cfm as part of the NBIS package.

Mesoscale and synoptic scale features of North Pacific weather systems observed with the scanning multichannel microwave radiometer on Nimbus 7

NASA Technical Reports Server (NTRS)

Katsaros, K. B.; Lewis, R. M.

1986-01-01

Employing data on integrated atmospheric water vapor, total cloud liquid water and rain rate obtainable from the Nimbus 7 Scanning Multichannel Microwave Radiometer (SMMR), the frontal structure of several mid-latitude cyclones over the North Pacific Ocean as they approach the West Coast of North America in the winter of 1979. The fronts, analyzed with all available independent data, are consistently located at the leading edge of the strongest gradient in integrated water vapor. The cloud liquid water content, which unfortunately has received very little in situ verification, has patterns which are consistent with the structure seen in visible and infrared imagery. The rain distribution is also a good indicator of frontal location and rain amounts are generally within a factor of two of what is observed with rain gauges on the coast. Furthermore, the onset of rain on the coast can often be accurately forecast by simple advection of the SMMR observed rain areas.

The 30/20 GHz demonstration system SSUS-D/BSE

NASA Technical Reports Server (NTRS)

1981-01-01

The systems consisting of a 30/20 GHz communication satellite featuring a multiple fixed beam and scanning beam antenna, SS-TDMA, onboard processing and high power TWT's and IMPATT amplifiers, a trunking space-diversity Earth station, a customer premise system (CPS) portable Earth station and a Master Control Station. Hardware, software and personnel are included to build and launch one satellite and to carry on a two year experimentation and demonstration period of advanced Ka-band systems concepts and technology. Included are first level plans identifying all tasks, a schedule for system development and an assessment of critical technology and risk and a preliminary experiments plan.

Executive Summary of the 2000 External Environmental Scan and the Internal Environmental Scan Report Card: Key Issues for Planning.

ERIC Educational Resources Information Center

Beachler, Judith

This document summarizes both the 2000 External Environmental Scan and the 2000 Internal Environmental Scan Report Card for the Los Rios Community College District (LRCCD) (California). LRCCD consists of American River College (ARC), Consummes River College (CRC), and Sacramento City College (SCC). Report highlights include: (1) total headcount…

Fast scanning mode and its realization in a scanning acoustic microscope

NASA Astrophysics Data System (ADS)

Ju, Bing-Feng; Bai, Xiaolong; Chen, Jian

2012-03-01

The scanning speed of the two-dimensional stage dominates the efficiency of mechanical scanning measurement systems. This paper focused on a detailed scanning time analysis of conventional raster and spiral scan modes and then proposed two fast alternative scanning modes. Performed on a self-developed scanning acoustic microscope (SAM), the measured images obtained by using the conventional scan mode and fast scan modes are compared. The total scanning time is reduced by 29% of the two proposed fast scan modes. It will offer a better solution for high speed scanning without sacrificing the system stability, and will not introduce additional difficulties to the configuration of scanning measurement systems. They can be easily applied to the mechanical scanning measuring systems with different driving actuators such as piezoelectric, linear motor, dc motor, and so on. The proposed fast raster and square spiral scan modes are realized in SAM, but not specially designed for it. Therefore, they have universal adaptability and can be applied to other scanning measurement systems with two-dimensional mechanical scanning stages, such as atomic force microscope or scanning tunneling microscope.

The morphology and histology of the male reproductive system in Dolycoris baccarum Linnaeus 1758 (Heteroptera: Pentatomidae)--light and scanning electron micoscope studies.

PubMed

Özyurt, Nurcan; Candan, Selami; Suludere, Zekiye

2013-01-01

The male reproductive system of Dolycoris baccarum (Linnaeus 1758) is studied morphologically and histologically using both light and scanning electron microscopes (SEM). The reproductive system of the male D. baccarum consists of a pair of testis, a pair of vas deferens, a pair of seminal vesicles, accessory glands (mesadenia, ectadenia), a bulbus ejaculatorius, a pair of ectodermal sacs, and a ductus ejaculatorius. The number of testicular follicles varies from four to six. The testicular follicles have three different development zones (growth zone, maturation zone, differentiation zone). The testes are connected to the seminal vesicles by the vas deferens. Vas deferens and seminal vesicles, which are fine-long and cylindrical. The seminal vesicle is connected with bulbus ejaculatorius which is balloon-shaped and surrounded with accessory glands. The bulbus ejaculatorius is continuous with ductus ejaculatorius which connected to the aedeagus. Copyright © 2012 Elsevier Ltd. All rights reserved.

Using a geographic information system and scanning technology to create high-resolution land-use data sets

USGS Publications Warehouse

Harvey, Craig A.; Kolpin, Dana W.; Battaglin, William A.

1996-01-01

A geographic information system (GIS) procedure was developed to compile low-altitude aerial photography, digitized data, and land-use data from U.S. Department of Agriculture Consolidated Farm Service Agency (CFSA) offices into a high-resolution (approximately 5 meters) land-use GIS data set. The aerial photography consisted of 35-mm slides which were scanned into tagged information file format (TIFF) images. These TIFF images were then imported into the GIS where they were registered into a geographically referenced coordinate system. Boundaries between land use were delineated from these GIS data sets using on-screen digitizing techniques. Crop types were determined using information obtained from the U.S. Department of Agriculture CFSA offices. Crop information not supplied by the CFSA was attributed by manual classification procedures. Automated methods to provide delineation of the field boundaries and land-use classification were investigated. It was determined that using these data sources, automated methods were less efficient and accurate than manual methods of delineating field boundaries and classifying land use.

Effect of sodium chloride on the glass transition of condensed starch systems.

PubMed

Chuang, Lillian; Panyoyai, Naksit; Shanks, Robert; Kasapis, Stefan

2015-10-01

The present investigation deals with the structural properties of condensed potato starch-sodium chloride systems undergoing a thermally induced glass transition. Sample preparation included hot pressing at 120°C for 7 min to produce extensive starch gelatinisation. Materials covered a range of moisture contents from 3.6% to 18.8%, which corresponded to relative humidity values of 11% and 75%. Salt addition was up to 6.0% in formulations. Instrumental work was carried out with dynamic mechanical analysis in tension, modulated differential scanning calorimetry, Fourier transform infrared spectroscopy, scanning electron microscopy and wide angle X-ray diffraction. Experimental conditions ensured the development of amorphous matrices that exhibited thermally reversible glassy consistency. Both moisture content and addition of sodium chloride affected the mechanical strength and glass transition temperature of polymeric systems. Sodium ions interact with chemical moieties of the polysaccharide chain to alter considerably structural properties, as compared to the starch-water matrix. Copyright © 2015. Published by Elsevier Ltd.

Exploring the architectural trade space of NASAs Space Communication and Navigation Program

NASA Astrophysics Data System (ADS)

Sanchez, M.; Selva, D.; Cameron, B.; Crawley, E.; Seas, A.; Seery, B.

NASAs Space Communication and Navigation (SCaN) Program is responsible for providing communication and navigation services to space missions and other users in and beyond low Earth orbit. The current SCaN architecture consists of three independent networks: the Space Network (SN), which contains the TDRS relay satellites in GEO; the Near Earth Network (NEN), which consists of several NASA owned and commercially operated ground stations; and the Deep Space Network (DSN), with three ground stations in Goldstone, Madrid, and Canberra. The first task of this study is the stakeholder analysis. The goal of the stakeholder analysis is to identify the main stakeholders of the SCaN system and their needs. Twenty-one main groups of stakeholders have been identified and put on a stakeholder map. Their needs are currently being elicited by means of interviews and an extensive literature review. The data will then be analyzed by applying Cameron and Crawley's stakeholder analysis theory, with a view to highlighting dominant needs and conflicting needs. The second task of this study is the architectural tradespace exploration of the next generation TDRSS. The space of possible architectures for SCaN is represented by a set of architectural decisions, each of which has a discrete set of options. A computational tool is used to automatically synthesize a very large number of possible architectures by enumerating different combinations of decisions and options. The same tool contains models to evaluate the architectures in terms of performance and cost. The performance model uses the stakeholder needs and requirements identified in the previous steps as inputs, and it is based in the VASSAR methodology presented in a companion paper. This paper summarizes the current status of the MIT SCaN architecture study. It starts by motivating the need to perform tradespace exploration studies in the context of relay data systems through a description of the history NASA's space communicati- n networks. It then presents the generalities of possible architectures for future space communication and navigation networks. Finally, it describes the tools and methods being developed, clearly indicating the architectural decisions that have been taken into account as well as the systematic approach followed to model them. The purpose of this study is to explore the SCaN architectural tradespace by means of a computational tool. This paper describes the tool, while the tradespace exploration is underway.

Ultrasonic immersion probes characterization for use in nondestructive testing according to EN 12668-2:2001

NASA Astrophysics Data System (ADS)

Silva, C. E. R.; Alvarenga, A. V.; Costa-Felix, R. P. B.

2011-02-01

Ultrasound is often used as a Non-Destructive Testing (NDT) technique to analyze components and structures to detect internal and surface flaws. To guarantee reliable measurements, it is necessary to calibrate instruments and properly assess related uncertainties. An important device of an ultrasonic instrument system is its probe, which characterization should be performed according to EN 12668-2. Concerning immersion probes beam profile, the parameters to be assessed are beam divergence, focal distance, width, and zone length. Such parameters are determined by scanning a reflector or a hydrophone throughout the transducer beam. Within the present work, a methodology developed at Inmetro's Laboratory of Ultrasound to evaluate relevant beam parameters is presented, based on hydrophone scan. Water bath and positioning system to move the hydrophone were used to perform the scan. Studied probes were excited by a signal generator, and the waterborne signals were detected by the hydrophone and acquired using an oscilloscope. A user-friendly virtual instrument was developed in LabVIEW to automate the system. The initial tests were performed using 1 and 2.25 MHz-ultrasonic unfocused probes (Ø 1.27 cm), and results were consistent with the manufacturer's specifications. Moreover, expanded uncertainties were lower than 6% for all parameters under consideration.

Dynamic autofocus for continuous-scanning time-delay-and-integration image acquisition in automated microscopy.

PubMed

Bravo-Zanoguera, Miguel E; Laris, Casey A; Nguyen, Lam K; Oliva, Mike; Price, Jeffrey H

2007-01-01

Efficient image cytometry of a conventional microscope slide means rapid acquisition and analysis of 20 gigapixels of image data (at 0.3-microm sampling). The voluminous data motivate increased acquisition speed to enable many biomedical applications. Continuous-motion time-delay-and-integrate (TDI) scanning has the potential to speed image acquisition while retaining sensitivity, but the challenge of implementing high-resolution autofocus operating simultaneously with acquisition has limited its adoption. We develop a dynamic autofocus system for this need using: 1. a "volume camera," consisting of nine fiber optic imaging conduits to charge-coupled device (CCD) sensors, that acquires images in parallel from different focal planes, 2. an array of mixed analog-digital processing circuits that measure the high spatial frequencies of the multiple image streams to create focus indices, and 3. a software system that reads and analyzes the focus data streams and calculates best focus for closed feedback loop control. Our system updates autofocus at 56 Hz (or once every 21 microm of stage travel) to collect sharply focused images sampled at 0.3x0.3 microm(2)/pixel at a stage speed of 2.3 mms. The system, tested by focusing in phase contrast and imaging long fluorescence strips, achieves high-performance closed-loop image-content-based autofocus in continuous scanning for the first time.

Two-color pump-probe laser spectroscopy instrument with picosecond time-resolved electronic delay and extended scan range

NASA Astrophysics Data System (ADS)

Yu, Anchi; Ye, Xiong; Ionascu, Dan; Cao, Wenxiang; Champion, Paul M.

2005-11-01

An electronically delayed two-color pump-probe instrument was developed using two synchronized laser systems. The instrument has picosecond time resolution and can perform scans over hundreds of nanoseconds without the beam divergence and walk-off effects that occur using standard spatial delay systems. A unique picosecond Ti :sapphire regenerative amplifier was also constructed without the need for pulse stretching and compressing optics. The picosecond regenerative amplifier has a broad wavelength tuning range, which suggests that it will make a significant contribution to two-color pump-probe experiments. To test this instrument we studied the rotational correlation relaxation of myoglobin (τr=8.2±0.5ns) in water as well as the geminate rebinding kinetics of oxygen to myoglobin (kg1=1.7×1011s-1, kg2=3.4×107s-1). The results are consistent with, and improve upon, previous studies.

Realization of a universal patient identifier for electronic medical records through biometric technology.

PubMed

Leonard, D C; Pons, Alexander P; Asfour, Shihab S

2009-07-01

The technology exists for the migration of healthcare data from its archaic paper-based system to an electronic one, and, once in digital form, to be transported anywhere in the world in a matter of seconds. The advent of universally accessible healthcare data has benefited all participants, but one of the outstanding problems that must be addressed is how the creation of a standardized nationwide electronic healthcare record system in the United States would uniquely identify and match a composite of an individual's recorded healthcare information to an identified individual patients out of approximately 300 million people to a 1:1 match. To date, a few solutions to this problem have been proposed that are limited in their effectiveness. We propose the use of biometric technology within our fingerprint, iris, retina scan, and DNA (FIRD) framework, which is a multiphase system whose primary phase is a multilayer consisting of these four types of biometric identifiers: 1) fingerprint; 2) iris; 3) retina scan; and 4) DNA. In addition, it also consists of additional phases of integration, consolidation, and data discrepancy functions to solve the unique association of a patient to their medical data distinctively. This would allow a patient to have real-time access to all of their recorded healthcare information electronically whenever it is necessary, securely with minimal effort, greater effectiveness, and ease.

High Dynamic Range Pixel Array Detector for Scanning Transmission Electron Microscopy.

PubMed

Tate, Mark W; Purohit, Prafull; Chamberlain, Darol; Nguyen, Kayla X; Hovden, Robert; Chang, Celesta S; Deb, Pratiti; Turgut, Emrah; Heron, John T; Schlom, Darrell G; Ralph, Daniel C; Fuchs, Gregory D; Shanks, Katherine S; Philipp, Hugh T; Muller, David A; Gruner, Sol M

2016-02-01

We describe a hybrid pixel array detector (electron microscope pixel array detector, or EMPAD) adapted for use in electron microscope applications, especially as a universal detector for scanning transmission electron microscopy. The 128×128 pixel detector consists of a 500 µm thick silicon diode array bump-bonded pixel-by-pixel to an application-specific integrated circuit. The in-pixel circuitry provides a 1,000,000:1 dynamic range within a single frame, allowing the direct electron beam to be imaged while still maintaining single electron sensitivity. A 1.1 kHz framing rate enables rapid data collection and minimizes sample drift distortions while scanning. By capturing the entire unsaturated diffraction pattern in scanning mode, one can simultaneously capture bright field, dark field, and phase contrast information, as well as being able to analyze the full scattering distribution, allowing true center of mass imaging. The scattering is recorded on an absolute scale, so that information such as local sample thickness can be directly determined. This paper describes the detector architecture, data acquisition system, and preliminary results from experiments with 80-200 keV electron beams.

SU-F-T-26: A Study of the Consistency of Brachytherapy Treatments for Vaginal Cuff

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shojaei, M; Pella, S; Dumitru, N

2016-06-15

Purpose: To evaluate to treatment consistency over the total number of fractions when treatment what HDR brachytherapy using the ML cylinders. At the same time the dosimetric impact on the critical organs is monitored over the total number of fractions. Methods: A retrospective analysis of 10 patients treated with Cylinder applicators, from 2015–2016 were considered for this study. The CT scans of these patients, taken before each treatment were separately imported in to the treatment planning system and paired with the initial CT scan after completing the contouring. Two sets of CT images were fused together with respective to themore » applicator, using landmark registration. The doses of each plan were imported as well and a cumulative dosimetric analysis was made for bladder, bowels, and rectum and PTV. Results: No contour of any of the OAR was exactly similar when CT images were fused on each other. The PTV volumes vary from fraction to fraction. There was always a difference between the doses received by the OARs between treatments. The maximum dose varied between 5% and 30% in rectum and bladder. The minimum dose varied between 5% and 8% in rectum and bladder. The average dose varied between 15% and 20% in rectum and bladder. Deviation in placement were noticed between fractions. Conclusion: The variation in volumes of OARs and isodoses near the OARs, indicate that the estimated doses to OARs on the planning system may not be the same dose delivered to the patient in all the fractions. There are no major differences between the prescribed dose and the delivered dose over the total number of fractions. In some cases the critical organs will benefit if the consecutive plans will made after the CT scans will be registered with the initial scan and then planned.« less

Automated matching of multiple terrestrial laser scans for stem mapping without the use of artificial references

NASA Astrophysics Data System (ADS)

Liu, Jingbin; Liang, Xinlian; Hyyppä, Juha; Yu, Xiaowei; Lehtomäki, Matti; Pyörälä, Jiri; Zhu, Lingli; Wang, Yunsheng; Chen, Ruizhi

2017-04-01

Terrestrial laser scanning has been widely used to analyze the 3D structure of a forest in detail and to generate data at the level of a reference plot for forest inventories without destructive measurements. Multi-scan terrestrial laser scanning is more commonly applied to collect plot-level data so that all of the stems can be detected and analyzed. However, it is necessary to match the point clouds of multiple scans to yield a point cloud with automated processing. Mismatches between datasets will lead to errors during the processing of multi-scan data. Classic registration methods based on flat surfaces cannot be directly applied in forest environments; therefore, artificial reference objects have conventionally been used to assist with scan matching. The use of artificial references requires additional labor and expertise, as well as greatly increasing the cost. In this study, we present an automated processing method for plot-level stem mapping that matches multiple scans without artificial references. In contrast to previous studies, the registration method developed in this study exploits the natural geometric characteristics among a set of tree stems in a plot and combines the point clouds of multiple scans into a unified coordinate system. Integrating multiple scans improves the overall performance of stem mapping in terms of the correctness of tree detection, as well as the bias and the root-mean-square errors of forest attributes such as diameter at breast height and tree height. In addition, the automated processing method makes stem mapping more reliable and consistent among plots, reduces the costs associated with plot-based stem mapping, and enhances the efficiency.

Minimum Detectable Activity for Tomographic Gamma Scanning System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venkataraman, Ram; Smith, Susan; Kirkpatrick, J. M.

2015-01-01

For any radiation measurement system, it is useful to explore and establish the detection limits and a minimum detectable activity (MDA) for the radionuclides of interest, even if the system is to be used at far higher values. The MDA serves as an important figure of merit, and often a system is optimized and configured so that it can meet the MDA requirements of a measurement campaign. The non-destructive assay (NDA) systems based on gamma ray analysis are no exception and well established conventions, such the Currie method, exist for estimating the detection limits and the MDA. However, the Tomographicmore » Gamma Scanning (TGS) technique poses some challenges for the estimation of detection limits and MDAs. The TGS combines high resolution gamma ray spectrometry (HRGS) with low spatial resolution image reconstruction techniques. In non-imaging gamma ray based NDA techniques measured counts in a full energy peak can be used to estimate the activity of a radionuclide, independently of other counting trials. However, in the case of the TGS each “view” is a full spectral grab (each a counting trial), and each scan consists of 150 spectral grabs in the transmission and emission scans per vertical layer of the item. The set of views in a complete scan are then used to solve for the radionuclide activities on a voxel by voxel basis, over 16 layers of a 10x10 voxel grid. Thus, the raw count data are not independent trials any more, but rather constitute input to a matrix solution for the emission image values at the various locations inside the item volume used in the reconstruction. So, the validity of the methods used to estimate MDA for an imaging technique such as TGS warrant a close scrutiny, because the pair-counting concept of Currie is not directly applicable. One can also raise questions as to whether the TGS, along with other image reconstruction techniques which heavily intertwine data, is a suitable method if one expects to measure samples whose activities are at or just above MDA levels. The paper examines methods used to estimate MDAs for a TGS system, and explores possible solutions that can be rigorously defended.« less

Scan-rescan reproducibility of diastolic left ventricular kinetic energy, viscous energy loss and vorticity assessment using 4D flow MRI: analysis in healthy subjects.

PubMed

Kamphuis, Vivian P; Westenberg, Jos J M; van der Palen, Roel L F; van den Boogaard, Pieter J; van der Geest, Rob J; de Roos, Albert; Blom, Nico A; Roest, Arno A W; Elbaz, Mohammed S M

2018-01-05

The aim of the current study was to assess the scan-rescan reproducibility of left ventricular (LV) kinetic energy (KE), viscous energy loss (EL) and vorticity during diastole from four-dimensional flow magnetic resonance imaging (4D flow MRI) in healthy subjects. Twelve volunteers (age 27 ± 3 years) underwent whole-heart 4D flow MRI twice in one session. In-scan consistency was evaluated by correlation between KE and EL. EL index was computed to measure the amount of EL relative to KE over diastole. Scan-rescan analysis was performed to test reproducibility of volumetric measurements of KE, EL, EL index and vorticity in the LV over early (E) and late (A) diastolic filling. In-scan consistency between KE and EL was strong-excellent (E-filling scan1: r = 0.92, P < 0.001; scan2: ρ = 0.96, P < 0.001 and A-filling scan1: ρ = 0.87, P < 0.001; scan2: r = 0.99, P < 0.001). For the majority of subjects (10 out of 12), KE and EL measures showed good to strong reproducibility. However, with a wide range of agreement [intraclass correlation (ICC): 0.64-0.95] and coefficients of variation (CV) ≤ 25%. EL index showed strong reproducibility for all 12 subjects with a strong ICC (0.94, P < 0.001) and a CV of 9%. Scan-rescan reproducibility of volumetric vorticity showed good-excellent ICCs (0.83-0.95) with CVs ≤ 11%. In conclusion, the current study shows strong-excellent in-scan consistency and overall good agreement between scans for 4D flow MRI assessment of left ventricular kinetic energy, energy loss and vorticity over diastole. However, substantial differences between the scans were also found in some parameters in two out of twelve subjects. Strong reproducibility was found in the dimensionless EL index , which measures the amount of viscous energy loss relative to the average kinetic energy over diastole.

Stereo Electro-optical Tracking System (SETS)

NASA Astrophysics Data System (ADS)

Koenig, E. W.

1984-09-01

The SETS is a remote, non-contacting, high-accuracy tracking system for the measurement of deflection of models in the National Transonic Facility at Langley Research Center. The system consists of four electronically scanned image dissector trackers which locate the position of Light Emitting Diodes embedded in the wing or body of aircraft models. Target location data is recorded on magnetic tape for later 3-D processing. Up to 63 targets per model may be tracked at typical rates of 1280 targets per second and to precision of 0.02mm at the target under the cold (-193 C) environment of the NTF tunnel.

Measurements of CO2 Concentration and Wind Profiles with A Scanning 1.6μm DIAL

NASA Astrophysics Data System (ADS)

Abo, M.; Shibata, Y.; Nagasawa, C.; Nagai, T.; Sakai, T.; Tsukamoto, M.

2012-12-01

Horizontal carbon dioxide (CO2) distribution and wind profiles are important information for understanding of the regional sink and source of CO2. The differential absorption lidar (DIAL) and the Doppler lidar with the range resolution is expected to bring several advantages over passive measurements. We have developed a new scanning 1.6μm DIAL and incoherent Doppler lidar system to perform simultaniously measurements of CO2 concentration and wind speed profiles in the atmosphere. The 1.6μm DIAL and Doppler lidar system consists of the Optical Parametric Generator (OPG) transmitter that excited by the LD pumped Nd:YAG laser with high repetition rate (500 Hz). The receiving optics include the near-infrared photomultiplier tube with high quantum efficiency operating at the photon counting mode, a fiber Bragg grating (FBG) filter to detct Doppler shift, and a 25 cm telescope[1][2]. Laser beam is transmitted coaxially and motorized scanning mirror system can scan the laser beam and field of view 0-360deg horizontally and 0-52deg vertically. We report the results of vertical CO2 scanning measurenents and vertical wind profiles. The scanning elevation angles were from 12deg to 24deg with angular step of 4deg and CO2 concentration profiles were obtained up to 1 km altitude with 200 m altitude resolution. We also obtained vertical wind vector profiles by measuring line-of-sight wind profiles at two azimuth angles with a fixed elevation angle 52deg. Vertical wind vector profiles were obtained up to 5 km altitude with 1 km altitude rasolution. This work was financially supported by the System Development Program for Advanced Measurement and Analysis of the Japan Science and Technology Agency. References [1] L. B. Vann, et al., "Narrowband fiber-optic phase-shifted Fabry-Perot Bragg grating filters for atmospheric water vapor lidar measurements", Appl. Opt., 44, pp. 7371-7377 (2005). [2] Y. Shibata, et al., "1.5μm incoherent Doppler lidar using a FBG filter", Proceedings of 25th International Laser Radar Conference (ILRC25), pp. 338-340 (2010)

High-throughput Raman chemical imaging for evaluating food safety and quality

NASA Astrophysics Data System (ADS)

Qin, Jianwei; Chao, Kuanglin; Kim, Moon S.

2014-05-01

A line-scan hyperspectral system was developed to enable Raman chemical imaging for large sample areas. A custom-designed 785 nm line-laser based on a scanning mirror serves as an excitation source. A 45° dichroic beamsplitter reflects the laser light to form a 24 cm x 1 mm excitation line normally incident on the sample surface. Raman signals along the laser line are collected by a detection module consisting of a dispersive imaging spectrograph and a CCD camera. A hypercube is accumulated line by line as a motorized table moves the samples transversely through the laser line. The system covers a Raman shift range of -648.7-2889.0 cm-1 and a 23 cm wide area. An example application, for authenticating milk powder, was presented to demonstrate the system performance. In four minutes, the system acquired a 512x110x1024 hypercube (56,320 spectra) from four 47-mm-diameter Petri dishes containing four powder samples. Chemical images were created for detecting two adulterants (melamine and dicyandiamide) that had been mixed into the milk powder.

Effectiveness and usability of Scanning Wizard software: a tool for enhancing switch scanning.

PubMed

Koester, Heidi Horstmann; Simpson, Richard C

2017-11-24

Scanning Wizard software helps scanning users improve the setup of their switch and scanning system. This study evaluated Scanning Wizard's effectiveness and usability. Ten people who use switch scanning and ten practitioners used Scanning Wizard in the initial session. Usability was high, based on survey responses averaging over 4.5 out of 5, and qualitative feedback was very positive. Five switch users were able to complete the multi-week protocol, using settings on their own scanning system that were recommended from the Scanning Wizard session. Using these revised settings, text entry rates improved by an average of 71%, ranging from 29% to 172% improvement. Results suggest that Scanning Wizard is a useful tool for improving the configuration of scanning systems for people who use switch scanning to communicate. Implications for Rehabilitation Some individuals with severe physical impairments use switch scanning for spoken and written communication. Scanning Wizard software helps scanning users improve the setup of their switch and scanning system. This study demonstrated high usability of Scanning Wizard (with 10 switch userpractitioner teams) and increased text entry rate by an average of 71% (for five switch users). Results suggest that Scanning Wizard is a useful tool for improving the configuration of scanning systems for people who use switch scanning to communicate.

The simulation of automatic ladar sensor control during flight operations using USU LadarSIM software

NASA Astrophysics Data System (ADS)

Pack, Robert T.; Saunders, David; Fullmer, Rees; Budge, Scott

2006-05-01

USU LadarSIM Release 2.0 is a ladar simulator that has the ability to feed high-level mission scripts into a processor that automatically generates scan commands during flight simulations. The scan generation depends on specified flight trajectories and scenes consisting of terrain and targets. The scenes and trajectories can either consist of simulated or actual data. The first modeling step produces an outline of scan footprints in xyz space. Once mission goals have been analyzed and it is determined that the scan footprints are appropriately distributed or placed, specific scans can then be chosen for the generation of complete radiometry-based range images and point clouds. The simulation is capable of quickly modeling ray-trace geometry associated with (1) various focal plane arrays and scanner configurations and (2) various scene and trajectories associated with particular maneuvers or missions.

Image processing, geometric modeling and data management for development of a virtual bone surgery system.

PubMed

Niu, Qiang; Chi, Xiaoyi; Leu, Ming C; Ochoa, Jorge

2008-01-01

This paper describes image processing, geometric modeling and data management techniques for the development of a virtual bone surgery system. Image segmentation is used to divide CT scan data into different segments representing various regions of the bone. A region-growing algorithm is used to extract cortical bone and trabecular bone structures systematically and efficiently. Volume modeling is then used to represent the bone geometry based on the CT scan data. Material removal simulation is achieved by continuously performing Boolean subtraction of the surgical tool model from the bone model. A quadtree-based adaptive subdivision technique is developed to handle the large set of data in order to achieve the real-time simulation and visualization required for virtual bone surgery. A Marching Cubes algorithm is used to generate polygonal faces from the volumetric data. Rendering of the generated polygons is performed with the publicly available VTK (Visualization Tool Kit) software. Implementation of the developed techniques consists of developing a virtual bone-drilling software program, which allows the user to manipulate a virtual drill to make holes with the use of a PHANToM device on a bone model derived from real CT scan data.

TDRS-L Pre-Launch Press Conference

NASA Image and Video Library

2014-01-21

CAPE CANAVERAL, Fla. – During a news conference at NASA's Kennedy Space Center in Florida, agency and contractor officials discussed preparations for the launch of NASA's Tracking and Data Relay Satellite, or TDRS-L, spacecraft. Participants included Andy Kopito, Civil Space Programs director for Boeing Space & Intelligence Systems in El Segundo, Calif. The TDRS-L spacecraft is the second of three new satellites designed to ensure vital operational continuity for NASA by expanding the lifespan of the Tracking and Data Relay Satellite System TDRSS fleet, which consists of eight satellites in geosynchronous orbit. The spacecraft provide tracking, telemetry, command and high bandwidth data return services for numerous science and human exploration missions orbiting Earth. These include NASA's Hubble Space Telescope and the International Space Station. TDRS-L has a high-performance solar panel designed for more spacecraft power to meet the growing S-band communications requirements. TDRSS is one of NASA Space Communication and Navigation’s SCaN three networks providing space communications to NASA’s missions. For more information more about TDRS-L, visit: http://www.nasa.gov/tdrs To learn more about SCaN, visit: www.nasa.gov/scan Photo credit: NASA/Frankie Martin

High resolution stationary digital breast tomosynthesis using distributed carbon nanotube x-ray source array.

PubMed

Qian, Xin; Tucker, Andrew; Gidcumb, Emily; Shan, Jing; Yang, Guang; Calderon-Colon, Xiomara; Sultana, Shabana; Lu, Jianping; Zhou, Otto; Spronk, Derrek; Sprenger, Frank; Zhang, Yiheng; Kennedy, Don; Farbizio, Tom; Jing, Zhenxue

2012-04-01

The purpose of this study is to investigate the feasibility of increasing the system spatial resolution and scanning speed of Hologic Selenia Dimensions digital breast tomosynthesis (DBT) scanner by replacing the rotating mammography x-ray tube with a specially designed carbon nanotube (CNT) x-ray source array, which generates all the projection images needed for tomosynthesis reconstruction by electronically activating individual x-ray sources without any mechanical motion. The stationary digital breast tomosynthesis (s-DBT) design aims to (i) increase the system spatial resolution by eliminating image blurring due to x-ray tube motion and (ii) reduce the scanning time. Low spatial resolution and long scanning time are the two main technical limitations of current DBT technology. A CNT x-ray source array was designed and evaluated against a set of targeted system performance parameters. Simulations were performed to determine the maximum anode heat load at the desired focal spot size and to design the electron focusing optics. Field emission current from CNT cathode was measured for an extended period of time to determine the stable life time of CNT cathode for an expected clinical operation scenario. The source array was manufactured, tested, and integrated with a Selenia scanner. An electronic control unit was developed to interface the source array with the detection system and to scan and regulate x-ray beams. The performance of the s-DBT system was evaluated using physical phantoms. The spatially distributed CNT x-ray source array comprised 31 individually addressable x-ray sources covering a 30 angular span with 1 pitch and an isotropic focal spot size of 0.6 mm at full width at half-maximum. Stable operation at 28 kV(peak) anode voltage and 38 mA tube current was demonstrated with extended lifetime and good source-to-source consistency. For the standard imaging protocol of 15 views over 14, 100 mAs dose, and 2 × 2 detector binning, the projection resolution along the scanning direction increased from 4.0 cycles/mm [at 10% modulation-transfer-function (MTF)] in DBT to 5.1 cycles/mm in s-DBT at magnification factor of 1.08. The improvement is more pronounced for faster scanning speeds, wider angular coverage, and smaller detector pixel sizes. The scanning speed depends on the detector, the number of views, and the imaging dose. With 240 ms detector readout time, the s-DBT system scanning time is 6.3 s for a 15-view, 100 mAs scan regardless of the angular coverage. The scanning speed can be reduced to less than 4 s when detectors become faster. Initial phantom studies showed good quality reconstructed images. A prototype s-DBT scanner has been developed and evaluated by retrofitting the Selenia rotating gantry DBT scanner with a spatially distributed CNT x-ray source array. Preliminary results show that it improves system spatial resolution substantially by eliminating image blur due to x-ray focal spot motion. The scanner speed of s-DBT system is independent of angular coverage and can be increased with faster detector without image degration. The accelerated lifetime measurement demonstrated the long term stability of CNT x-ray source array with typical clinical operation lifetime over 3 years.

Obstacles to Industrial Implementation of Scanning Systems

Treesearch

Anders Astrom; Olog Broman; John Graffman; Anders Gronlund; Armas Jappinene; Jari Luostarinen; Jan Nystrom; Daniel L. Schmoldt

1998-01-01

Initially the group discussed what is meant by scanning systems. An operational definition was adopted to consider scanning system in the current context to be nontraditional scanning. Where, traditional scanning is defined as scanning that has been industrially operational and relatively common for several years-a mature technology. For example,...

An Audit of Second-Trimester Fetal Anomaly Scans Based on a Novel Image-Scoring Method in the Southwest Region of the Netherlands.

PubMed

Ursem, Nicolette T C; Peters, Ingrid A; Kraan-van der Est, Mieke N; Reijerink-Verheij, Jacqueline C I Y; Knapen, Maarten F C M; Cohen-Overbeek, Titia E

2017-06-01

Since 2007 the second-trimester fetal anomaly scan is offered to all pregnant women as part of the national prenatal screening program in the Netherlands. Dutch population-based screening programs generally have a well-described system to achieve quality assurance. Because of the absence of a uniform system to monitor the actual performance of the fetal anomaly scan in 2012, we developed a standardized image-scoring method. The aim of this study was to evaluate the scanning performance of all sonographers in the southwestern region of the Netherlands using this image-scoring method. Each sonographer was requested to set up a digital portfolio. A portfolio consists of five logbooks from five different pregnant women, each containing 25 fetal anatomical structures and six biometric measures of randomly selected fetal anomaly scans. During the study period, 425 logbooks of 85 sonographers were assessed as part of the audit process. Seventy-three out of 85 sonographers (86%) met the criteria in the primary audit, and 12 sonographers required individual hands-on training. A successful assessment was achieved for 11 sonographers in the re-audit and one sonographer ceased her contract. Moreover, 2.1% of the required images were not digitally stored and therefore could not be reviewed. Quality assessment using the image-scoring method demonstrated that most of the sonographers met the expectations of the audit process, but those who had subpar performance met the expectations after retraining. © 2017 by the American Institute of Ultrasound in Medicine.

Online compensation for target motion with scanned particle beams: simulation environment.

PubMed

Li, Qiang; Groezinger, Sven Oliver; Haberer, Thomas; Rietzel, Eike; Kraft, Gerhard

2004-07-21

Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. This paper presents a simulation environment in which the time-dependent effect of target motion on heavy-ion irradiation can be calculated with dynamically scanned ion beams. In an extension of the existing treatment planning software for ion irradiation of static targets (TRiP) at GSI, the expected dose distribution is calculated as the sum of several sub-distributions for single target motion states. To investigate active compensation for target motion by adapting the position of the therapeutic beam during irradiation, the planned beam positions can be altered during the calculation. Applying realistic parameters to the planned motion-compensation methods at GSI, the effect of target motion on the expected dose uniformity can be simulated for different target configurations and motion conditions. For the dynamic dose calculation, experimentally measured profiles of the beam extraction in time were used. Initial simulations show the feasibility and consistency of an active motion compensation with the magnetic scanning system and reveal some strategies to improve the dose homogeneity inside the moving target. The simulation environment presented here provides an effective means for evaluating the dose distribution for a moving target volume with and without motion compensation. It contributes a substantial basis for the experimental research on the irradiation of moving target volumes with scanned ion beams at GSI which will be presented in upcoming papers.

Development of a c-scan photoacoutsic imaging probe for prostate cancer detection

NASA Astrophysics Data System (ADS)

Valluru, Keerthi S.; Chinni, Bhargava K.; Rao, Navalgund A.; Bhatt, Shweta; Dogra, Vikram S.

2011-03-01

Prostate cancer is the second leading cause of death in American men after lung cancer. The current screening procedures include Digital Rectal Exam (DRE) and Prostate Specific Antigen (PSA) test, along with Transrectal Ultrasound (TRUS). All suffer from low sensitivity and specificity in detecting prostate cancer in early stages. There is a desperate need for a new imaging modality. We are developing a prototype transrectal photoacoustic imaging probe to detect prostate malignancies in vivo that promises high sensitivity and specificity. To generate photoacoustic (PA) signals, the probe utilizes a high energy 1064 nm laser that delivers light pulses onto the prostate at 10Hz with 10ns duration through a fiber optic cable. The designed system will generate focused C-scan planar images using acoustic lens technology. A 5 MHz custom fabricated ultrasound sensor array located in the image plane acquires the focused PA signals, eliminating the need for any synthetic aperture focusing. The lens and sensor array design was optimized towards this objective. For fast acquisition times, a custom built 16 channel simultaneous backend electronics PCB has been developed. It consists of a low-noise variable gain amplifier and a 16 channel ADC. Due to the unavailability of 2d ultrasound arrays, in the current implementation several B-scan (depth-resolved) data is first acquired by scanning a 1d array, which is then processed to reconstruct either 3d volumetric images or several C-scan planar images. Experimental results on excised tissue using a in-vitro prototype of this technology are presented to demonstrate the system capability in terms of resolution and sensitivity.

Development and Verification of Body Armor Target Geometry Created Using Computed Tomography Scans

DTIC Science & Technology

2017-07-13

designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or approval of...modeling consisted of manual measurement of armor systems and translating those measurements to computer-aided design geometry, which can be tedious and...computer-aided design (CAD) human geometry model (referred to throughout as ORCA man) that is used in the Operational Requirement-based Casualty Assessment

Computer aided detection of brain micro-bleeds in traumatic brain injury

NASA Astrophysics Data System (ADS)

van den Heuvel, T. L. A.; Ghafoorian, M.; van der Eerden, A. W.; Goraj, B. M.; Andriessen, T. M. J. C.; ter Haar Romeny, B. M.; Platel, B.

2015-03-01

Brain micro-bleeds (BMBs) are used as surrogate markers for detecting diffuse axonal injury in traumatic brain injury (TBI) patients. The location and number of BMBs have been shown to influence the long-term outcome of TBI. To further study the importance of BMBs for prognosis, accurate localization and quantification are required. The task of annotating BMBs is laborious, complex and prone to error, resulting in a high inter- and intra-reader variability. In this paper we propose a computer-aided detection (CAD) system to automatically detect BMBs in MRI scans of moderate to severe neuro-trauma patients. Our method consists of four steps. Step one: preprocessing of the data. Both susceptibility (SWI) and T1 weighted MRI scans are used. The images are co-registered, a brain-mask is generated, the bias field is corrected, and the image intensities are normalized. Step two: initial candidates for BMBs are selected as local minima in the processed SWI scans. Step three: feature extraction. BMBs appear as round or ovoid signal hypo-intensities on SWI. Twelve features are computed to capture these properties of a BMB. Step four: Classification. To identify BMBs from the set of local minima using their features, different classifiers are trained on a database of 33 expert annotated scans and 18 healthy subjects with no BMBs. Our system uses a leave-one-out strategy to analyze its performance. With a sensitivity of 90% and 1.3 false positives per BMB, our CAD system shows superior results compared to state-of-the-art BMB detection algorithms (developed for non-trauma patients).

New Research by CCD Scanning for Comets and Asteroids

NASA Technical Reports Server (NTRS)

Gehrels, Tom

1997-01-01

Spacewatch was begun in 1980; its purpose is to explore the various populations of small objects within the solar system. Spacewatch provides data for studies of comets and asteroids, finds potential targets for space missions, and provides information on the environmental problem of possible impacts. Moving objects are discovered by scanning the sky with charge-coupled devices (CCDS) on the 0.9-meter Spacewatch Telescope of the University of Arizona on Kitt Peak. Each Spacewatch scan consists of three drift scan passes over an area of sky using a CCD filtered to a bandpass of 0.5-1.0 pm (approximately V+R+I with peak sensitivity at 0.7 pm). The effective exposure time for each pass is 143 seconds multiplied by the secant of the declination. The area covered by each scan is 32 arcminutes in declination by about 28 minutes of time in right ascension. The image scale is 1.05 arcseconds per pixel. Three passes take about 1.5 hours to complete and show motions of individual objects over a one hour time baseline. The limiting magnitude is about 21.5 in single scans. CCD scanning was developed by Spacewatch in the early 1980s, with improvements still being made - particularly by bringing a new 1.8-m Spacewatch Telescope on line. In the meantime, we have been finding some 30,000 new asteroids per year and applying their statistics to the study of the collisional history of the solar system. Spacewatch had found a total of 150 Near-Earth Asteroids (NEAS) and 8 new comets, and had recovered one lost comet (P/Spitaler in 1993). Spacewatch is also efficient in recovery of known comets and has detected and reported positions for more than 137,000 asteroids, mostly new ones in the main belt, including more than 10,882 asteroids designated by the Minor Planet Center (MPC).

Hyperspectral imaging fluorescence excitation scanning for colon cancer detection

NASA Astrophysics Data System (ADS)

Leavesley, Silas J.; Walters, Mikayla; Lopez, Carmen; Baker, Thomas; Favreau, Peter F.; Rich, Thomas C.; Rider, Paul F.; Boudreaux, Carole W.

2016-10-01

Optical spectroscopy and hyperspectral imaging have shown the potential to discriminate between cancerous and noncancerous tissue with high sensitivity and specificity. However, to date, these techniques have not been effectively translated to real-time endoscope platforms. Hyperspectral imaging of the fluorescence excitation spectrum represents new technology that may be well suited for endoscopic implementation. However, the feasibility of detecting differences between normal and cancerous mucosa using fluorescence excitation-scanning hyperspectral imaging has not been evaluated. The goal of this study was to evaluate the initial feasibility of using fluorescence excitation-scanning hyperspectral imaging for measuring changes in fluorescence excitation spectrum concurrent with colonic adenocarcinoma using a small pre-pilot-scale sample size. Ex vivo analysis was performed using resected pairs of colorectal adenocarcinoma and normal mucosa. Adenocarcinoma was confirmed by histologic evaluation of hematoxylin and eosin (H&E) permanent sections. Specimens were imaged using a custom hyperspectral imaging fluorescence excitation-scanning microscope system. Results demonstrated consistent spectral differences between normal and cancerous tissues over the fluorescence excitation range of 390 to 450 nm that could be the basis for wavelength-dependent detection of colorectal cancers. Hence, excitation-scanning hyperspectral imaging may offer an alternative approach for discriminating adenocarcinoma from surrounding normal colonic mucosa, but further studies will be required to evaluate the accuracy of this approach using a larger patient cohort.

Facility for low-temperature spin-polarized-scanning tunneling microscopy studies of magnetic/spintronic materials prepared in situ by nitride molecular beam epitaxy.

PubMed

Lin, Wenzhi; Foley, Andrew; Alam, Khan; Wang, Kangkang; Liu, Yinghao; Chen, Tianjiao; Pak, Jeongihm; Smith, Arthur R

2014-04-01

Based on the interest in, as well as exciting outlook for, nitride semiconductor based structures with regard to electronic, optoelectronic, and spintronic applications, it is compelling to investigate these systems using the powerful technique of spin-polarized scanning tunneling microscopy (STM), a technique capable of achieving magnetic resolution down to the atomic scale. However, the delicate surfaces of these materials are easily corrupted by in-air transfers, making it unfeasible to study them in stand-alone ultra-high vacuum STM facilities. Therefore, we have carried out the development of a hybrid system including a nitrogen plasma assisted molecular beam epitaxy/pulsed laser epitaxy facility for sample growth combined with a low-temperature, spin-polarized scanning tunneling microscope system. The custom-designed molecular beam epitaxy growth system supports up to eight sources, including up to seven effusion cells plus a radio frequency nitrogen plasma source, for epitaxially growing a variety of materials, such as nitride semiconductors, magnetic materials, and their hetero-structures, and also incorporating in situ reflection high energy electron diffraction. The growth system also enables integration of pulsed laser epitaxy. The STM unit has a modular design, consisting of an upper body and a lower body. The upper body contains the coarse approach mechanism and the scanner unit, while the lower body accepts molecular beam epitaxy grown samples using compression springs and sample skis. The design of the system employs two stages of vibration isolation as well as a layer of acoustic noise isolation in order to reduce noise during STM measurements. This isolation allows the system to effectively acquire STM data in a typical lab space, which during its construction had no special and highly costly elements included, (such as isolated slabs) which would lower the environmental noise. The design further enables tip exchange and tip coating without breaking vacuum, and convenient visual access to the sample and tip inside a superconducting magnet cryostat. A sample/tip handling system is optimized for both the molecular beam epitaxy growth system and the scanning tunneling microscope system. The sample/tip handing system enables in situ STM studies on epitaxially grown samples, and tip exchange in the superconducting magnet cryostat. The hybrid molecular beam epitaxy and low temperature scanning tunneling microscopy system is capable of growing semiconductor-based hetero-structures with controlled accuracy down to a single atomic-layer and imaging them down to atomic resolution.

Heterodyne Interferometry with a Scanning Optical Microscope.

NASA Astrophysics Data System (ADS)

Hobbs, Philip Charles Danby

The design and implementation of a confocal optical microscope which functions as an electronically scanned heterodyne interferometer are described. Theoretical models based on Fourier optics for general samples and on exact series solution of the scalar Helmholtz equation for a class of trench structures are developed and compared with experimental data. Good agreement is obtained. The associated data acquisition system, also described, enables the system to measure both the amplitude (to 12 bits) and the phase (to 0.1^circ) of a returned optical beam, at a continuous rate of 30,000 points per second. The microscope system uses a wide-band tellurium dioxide acousto-optic cell for electronic scanning, frequency shifting, and beam splitting/combining. It uses a stationary reference beam on the sample for vibration cancellation, which results in a system of great vibration immunity. It can measure relief ranging from a few tenths of a micron down to a few Angstroms, and line widths down to well below 0.4 micron, using light of 0.5 micron wavelength. Angstrom resolution can be achieved in a single full-speed scan, without special vibration isolation equipment, providing that folding mirrors are avoided. A signal processing algorithm based on Fourier deconvolution is presented; it takes advantage of the extra bandwidth of a confocal system and the availability of both amplitude and phase, to improve the lateral resolution by approximately a factor of two. Experimental results are shown, which demonstrate phase edge resolution (10%-90%) of 0.45 lambda (raw data), and 0.18 lambda (after filtering), in excellent agreement with the Fourier optics prediction. The exact scalar theory calculates the response of the microscope as it scans over an infinitely long rectangular trench in a plane boundary on which Dirichlet boundary conditions apply. An expansion in cavity modes inside the trench is used to match the field and its derivatives across the mouth of the trench to get the self-consistent solution. A listing is appended of a program for an HP personal computer which performs the simulation in 1 to 5 minutes' running time for most cases. The trench theory is compared with the Fourier theory and with experimental results for actual metal trenches, with good results.

Towards Consistent Aerosol and Cloud Climate Data Records from the Along Track Scanning Radiometer instruments

NASA Astrophysics Data System (ADS)

Thomas, G.

2015-12-01

The ESA Climate Change Initiative (CCI) programme has provided a mechanism for the production of new long-term data records of essential climate variables (ECVs) defined by WMO Global Climate Observing System (GCOS). These include consistent cloud (from the MODIS, AVHRR, ATSR-2 and AATSR instruments) and aerosol (from ATSR-2 and AATSR) products produced using the Optimal Retrieval of Aerosol and Cloud (ORAC) scheme. This talk will present an overview of the newly produced ORAC cloud and aerosol datasets, their evaluation and a joint aerosol-cloud product produced for the 1995-2012 ATSR-2-AATSR data record.

A 3D NO2 DOAS System to Capture Urban Concentrations

NASA Astrophysics Data System (ADS)

Wenig, M.; Chan, L.; Zhu, Y.; Schütt, A. M. N.; Kuhlmann, G.; Brunner, D.

2016-12-01

The Munich 3D DOAS measuring system combines four different types of DOAS measurement techniques and is installed on the roof of the building of the LMU Meteorological Institute at the center of Munich. In order to get a complete picture of the NO2 distribution we utilize a sensor fusion concept consisting of three longpath-DOAS instruments (LP-DOAS) scanning retroreflectors in different directions and distances, a multi-axis DOAS instrument (MAX-DOAS) performing elevation scans in different azimuth directions which is also capable to look directly into the sun allowing direct sun DOAS measurements, and a mobile cavity-enhanced DOAS instruments (CE-DOAS) capturing the citywide street level NO2 concentrations.The map from the mobile CE-DOAS is corrected for diurnal variations using the LP-DOAS data and a daily cycle analysis to get a consistent NO2 map. The LP-DOAS data averages over several kilometers and uses different measurement paths to capture the horizontal variations at roof top level. This data set will also be used to constrain the vertical profile shapes retrieved from the MAX-DOAS inversion. Constraining ground concentrations using the LP-DOAS and the total columns from the direct sun DOAS measurements allows us to retrieve additional profile parameters characterizing a radial component of fitted profiles which then leads to estimated 3D distributions putting together different azimuth scan results.The resulting data set is very valuable for satellite validation (e.g. OMI NO2) since we cover an area similar to an OMI ground pixel and provide the vertical profile to eliminate the biggest error source for the AMF calculation for the retrieval algorithm. We are also comparing our results to local measurement stations.

Attenuation Drift in the Micro-Computed Tomography System at LLNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dooraghi, Alex A.; Brown, William; Seetho, Isaac

2016-01-12

The maximum allowable level of drift in the linear attenuation coefficients (μ) for a Lawrence Livermore National Laboratory (LLNL) micro-computed tomography (MCT) system was determined to be 0.1%. After ~100 scans were acquired during the period of November 2014 to March 2015, the drift in μ for a set of six reference materials reached or exceeded 0.1%. Two strategies have been identified to account for or correct the drift. First, normalizing the 160 kV and 100 kV μ data by the μ of water at the corresponding energy, in contrast to conducting normalization at the 160 kV energy only, significantlymore » compensates for measurement drift. Even after the modified normalization, μ of polytetrafluoroethylene (PTFE) increases linearly with scan number at an average rate of 0.00147% per scan. This is consistent with PTFE radiation damage documented in the literature. The second strategy suggested is the replacement of the PTFE reference with fluorinated ethylene propylene (FEP), which has the same effective atomic number (Ze) and electron density (ρe) as PTFE, but is 10 times more radiation resistant. This is important as effective atomic number and electron density are key parameters in analysis. The presence of a material with properties such as PTFE, when taken together with the remaining references, allows for a broad range of the (Ze, ρe) feature space to be used in analysis. While FEP is documented as 10 times more radiation resistant, testing will be necessary to assess how often, if necessary, FEP will need to be replaced. As radiation damage to references has been observed, it will be necessary to monitor all reference materials for radiation damage to ensure consistent x-ray characteristics of the references.« less

Analytical and numerical analysis of imaging mechanism of dynamic scanning electron microscopy.

PubMed

Schröter, M-A; Holschneider, M; Sturm, H

2012-11-02

The direct observation of small oscillating structures with the help of a scanning electron beam is a new approach to study the vibrational dynamics of cantilevers and microelectromechanical systems. In the scanning electron microscope, the conventional signal of secondary electrons (SE, dc part) is separated from the signal response of the SE detector, which is correlated to the respective excitation frequency for vibration by means of a lock-in amplifier. The dynamic response is separated either into images of amplitude and phase shift or into real and imaginary parts. Spatial resolution is limited to the diameter of the electron beam. The sensitivity limit to vibrational motion is estimated to be sub-nanometer for high integration times. Due to complex imaging mechanisms, a theoretical model was developed for the interpretation of the obtained measurements, relating cantilever shapes to interaction processes consisting of incident electron beam, electron-lever interaction, emitted electrons and detector response. Conclusions drawn from this new model are compared with numerical results based on the Euler-Bernoulli equation.

Design of a handheld optical coherence microscopy endoscope

NASA Astrophysics Data System (ADS)

Korde, Vrushali R.; Liebmann, Erica; Barton, Jennifer K.

2011-06-01

Optical coherence microscopy (OCM) combines coherence gating, high numerical aperture optics, and a fiber-core pinhole to provide high axial and lateral resolution with relatively large depth of imaging. We present a handheld rigid OCM endoscope designed for small animal surgical imaging, with a 6-mm diam tip, 1-mm scan width, and 1-mm imaging depth. X-Y scanning is performed distally with mirrors mounted to micro galvonometer scanners incorporated into the endoscope handle. The endoscope optical design consists of scanning doublets, an afocal Hopkins relay lens system, a 0.4 numerical aperture water immersion objective, and a cover glass. This endoscope can resolve laterally a 1.4-μm line pair feature and has an axial resolution (full width half maximum) of 5.4 μm. Images taken with this endoscope of fresh ex-vivo mouse ovaries show structural features, such as corpus luteum, primary follicles, growing follicles, and fallopian tubes. This rigid handheld OCM endoscope can be useful for a variety of minimally invasive and surgical imaging applications.

A collection of non-human primate computed tomography scans housed in MorphoSource, a repository for 3D data

PubMed Central

Copes, Lynn E.; Lucas, Lynn M.; Thostenson, James O.; Hoekstra, Hopi E.; Boyer, Doug M.

2016-01-01

A dataset of high-resolution microCT scans of primate skulls (crania and mandibles) and certain postcranial elements was collected to address questions about primate skull morphology. The sample consists of 489 scans taken from 431 specimens, representing 59 species of most Primate families. These data have transformative reuse potential as such datasets are necessary for conducting high power research into primate evolution, but require significant time and funding to collect. Similar datasets were previously only available to select research groups across the world. The physical specimens are vouchered at Harvard’s Museum of Comparative Zoology. The data collection took place at the Center for Nanoscale Systems at Harvard. The dataset is archived on MorphoSource.org. Though this is the largest high fidelity comparative dataset yet available, its provisioning on a web archive that allows unlimited researcher contributions promises a future with vastly increased digital collections available at researchers’ finger tips. PMID:26836025

Multi-Mounted X-Ray Computed Tomography

PubMed Central

Fu, Jian; Liu, Zhenzhong; Wang, Jingzheng

2016-01-01

Most existing X-ray computed tomography (CT) techniques work in single-mounted mode and need to scan the inspected objects one by one. It is time-consuming and not acceptable for the inspection in a large scale. In this paper, we report a multi-mounted CT method and its first engineering implementation. It consists of a multi-mounted scanning geometry and the corresponding algebraic iterative reconstruction algorithm. This approach permits the CT rotation scanning of multiple objects simultaneously without the increase of penetration thickness and the signal crosstalk. Compared with the conventional single-mounted methods, it has the potential to improve the imaging efficiency and suppress the artifacts from the beam hardening and the scatter. This work comprises a numerical study of the method and its experimental verification using a dataset measured with a developed multi-mounted X-ray CT prototype system. We believe that this technique is of particular interest for pushing the engineering applications of X-ray CT. PMID:27073911

Reducing background noise in near-infrared medical imaging: Routes to activated fluorescing

NASA Astrophysics Data System (ADS)

Burdette, Mary K.; Bandera, Yuriy; Powell, Rhonda R.; Bruce, Terri F.; Foulger, Stephen H.

2016-03-01

Activated fluorescence was achieved for nanoparticle based systems. One particulate system consisting of a poly(propargyl acrylate) (PA) core with covalently attached derivatized fluorescein and modified bovine serum albumin covalently conjugated to a cyanine 3 derivative was initially nonfluorescent. Upon trypsin addition and subsequent proteolytic digestion, Förster resonance energy transfer (FRET) was induced. The other particulate system consisted of a PA core with covalently attached azide modified BSA, which was covalently attached to a silicon phthalocyanine derivative (PA/BSA/akSiPc600). Both systems were biocompatible. To investigate activated fluorescence with the PA/BSA/akSiPc600 system in cancer cells, human non-small cell lung cancer cells (A549 cell line) were used as a model system. The PA/BSA/akSiPc600 system was incubated with the cells at varying time points in an effort to see a fluorescence increase over time as the cells uptake the particles and as they digest the BSA, most probably, via endocytosis. It was seen, through live cell scanning confocal microscopy, that the fluorescence was activated in the cell.

New fiber laser for lidar developments in disaster management

NASA Astrophysics Data System (ADS)

Besson, C.; Augere, B.; Canat, G.; Cezard, N.; Dolfi-Bouteyre, A.; Fleury, D.; Goular, D.; Lombard, L.; Planchat, C.; Renard, W.; Valla, M.

2014-10-01

Recent progress in fiber technology has enabled new laser designs along with all fiber lidar architectures. Their asset is to avoid free-space optics, sparing lengthy alignment procedures and yielding compact setups that are well adapted for field operations and on board applications thanks to their intrinsic vibration-resistant architectures. We present results in remote sensing for disaster management recently achieved with fiber laser systems. Field trials of a 3-paths lidar vibrometer for the remote study of modal parameters of buildings has shown that application-related constraints were fulfilled and that the obtained results are consistent with simultaneous in situ seismic sensors measurements. Remote multi-gas detection can be obtained using broadband infrared spectroscopy. Results obtained on methane concentration measurement using an infrared supercontinuum fiber laser and analysis in the 3-4 μm band are reported. For gas flux retrieval, air velocity measurement is also required. Long range scanning all-fiber wind lidars are now available thanks to innovative laser architectures. High peak power highly coherent pulses can be extracted from Er3+:Yb3+ and Tm3+ active fibers using methods described in the paper. The additional laser power provides increased coherent lidar capability in range and scanning of large areas but also better system resistance to adverse weather conditions. Wind sensing at ranges beyond 10 km have been achieved and on-going tests of a scanning system dedicated to airport safety is reported.

Design of the scanning mode coated glass color difference online detection system

NASA Astrophysics Data System (ADS)

Bi, Weihong; Zhang, Yu; Wang, Dajiang; Zhang, Baojun; Fu, Guangwei

2008-03-01

A design of scanning mode coated glass color difference online detection system was introduced. The system consisted of color difference data acquirement part and orbit control part. The function of the color difference data acquirement part was to acquire glass spectral reflectance and then processed them to get the color difference value. Using fiber for light guiding, the reflected light from surface of glass was transmitted into light division part, and the dispersive light was imaged on linear CCD, and then the output signals from the CCD was sampled pixel by pixel, and the spectral reflectance of coated glass was obtained finally. Then, the acquired spectral reflectance signals was sent to industrial personal computer through USB interface, using standard color space and color difference formula nominated by International Commission on Illumination (CIE) in 1976 to process these signals, and the reflected color parameter and color difference of coated glass was gained in the end. The function of the orbit control part was to move the detection probe by way of transverse scanning mode above the glass strip, and control the measuring start-stop time of the color difference data acquirement part at the same time. The color difference data acquirement part of the system was put on the orbit which is after annealing area in coated glass production line, and the protected fiber probe was placed on slide of the orbit. Using single chip microcomputer to control transmission mechanism of the slide, which made the slide move by way of transverse scanning mode on the glass strip, meanwhile, the color difference data acquirement part of the system was also controlled by the single chip microcomputer, and it made the acquirement part measure color difference data when the probe reached the needed working speed and required place on the glass strip. The scanning mode coated glass color difference online detection system can measure color parameter and color difference of each transverse point on glass strip, it can also measure lengthways color stability on glass strip. Furthermore, the measuring results can be transmitted to coated control room through intranet, so it is very useful to improve producing technique in time. In addition, equipping necessary marking machine, this system can classify glass board automatically based on the measuring result.

99mTc Sestamibi Thyroid Scan in Amiodarone-Induced Thyrotoxicosis Type I.

PubMed

Patel, Niraj R; Tamara, Luis A; Lee, Ho

2016-07-01

Amiodarone-induced thyrotoxicosis (AIT) type I describes inducement of clinical hyperthyroidism by excessive thyroidal iodine in the setting of latent Graves disease, and therapy differs from that used for AIT type II. A 65-year-old man previously on amiodarone for atrial fibrillation developed clinical hyperthyroidism. Diagnosis of AIT was made, but the type was not clear. Tc sestamibi thyroid scan showed diffusely increased uptake and retention in an enlarged thyroid gland, a pattern consistent with AIT type I. Methimazole was initiated and controlled the thyrotoxicosis. I iodide thyroid scan and uptake study performed later was consistent with Graves disease.

Double-layered microstrip metamaterial beam scanning leaky wave antenna with consistent gain and low cross-polarization

NASA Astrophysics Data System (ADS)

An, Yong-li; Tan, Yi-li; Zhang, Hong-bo; Wu, Guo-cheng

2017-12-01

In this paper, a novel double-layered microstrip metamaterial beam scanning leaky wave antenna (LWA) is proposed and investigated to achieve consistent gain and low cross-polarization. Thanks to the continuous phase constant changing from negative to positive values over the passband of the double-layered microstrip metamaterial, the proposed LWA, which consists of 20 identical microstrip metamaterial unit cells, can obtain a continuous beam scanning property from backward to forward directions. The proposed LWA is fabricated and measured. The measured results show that the fabricated antenna obtains a continuous beam scanning angle of 140° over the operating frequency band of 3.80-5.25 GHz (32%), the measured 3 dB gain bandwidth is 30.17% with maximum gain of 11.7 dB. Besides, the measured cross-polarization of the fabricated antenna keeps at a level of at least 30 dB below the co-polarization across the entire radiation region. Moreover, the measured and simulated results are in good agreement with each other, indicating the significance and effectiveness of this method.

An x-ray fluorescence imaging system for gold nanoparticle detection.

PubMed

Ricketts, K; Guazzoni, C; Castoldi, A; Gibson, A P; Royle, G J

2013-11-07

Gold nanoparticles (GNPs) may be used as a contrast agent to identify tumour location and can be modified to target and image specific tumour biological parameters. There are currently no imaging systems in the literature that have sufficient sensitivity to GNP concentration and distribution measurement at sufficient tissue depth for use in in vivo and in vitro studies. We have demonstrated that high detecting sensitivity of GNPs can be achieved using x-ray fluorescence; furthermore this technique enables greater depth imaging in comparison to optical modalities. Two x-ray fluorescence systems were developed and used to image a range of GNP imaging phantoms. The first system consisted of a 10 mm(2) silicon drift detector coupled to a slightly focusing polycapillary optic which allowed 2D energy resolved imaging in step and scan mode. The system has sensitivity to GNP concentrations as low as 1 ppm. GNP concentrations different by a factor of 5 could be resolved, offering potential to distinguish tumour from non-tumour. The second system was designed to avoid slow step and scan image acquisition; the feasibility of excitation of the whole specimen with a wide beam and detection of the fluorescent x-rays with a pixellated controlled drift energy resolving detector without scanning was investigated. A parallel polycapillary optic coupled to the detector was successfully used to ascertain the position where fluorescence was emitted. The tissue penetration of the technique was demonstrated to be sufficient for near-surface small-animal studies, and for imaging 3D in vitro cellular constructs. Previous work demonstrates strong potential for both imaging systems to form quantitative images of GNP concentration.

Whole-body muscle MRI in 20 patients suffering from late onset Pompe disease: Involvement patterns.

PubMed

Carlier, Robert-Yves; Laforet, Pascal; Wary, Claire; Mompoint, Dominique; Laloui, Kenza; Pellegrini, Nadine; Annane, Djillali; Carlier, Pierre G; Orlikowski, David

2011-11-01

To describe muscle involvement on whole-body MRI scans in adult patients at different stages of late-onset Pompe disease. Twenty patients aged 37 to 75 were examined. Five were bedridden and required ventilatory support. Axial and coronal T1 turbo-spin-echo sequences were performed on 1.5T or 3T systems. MRI was scored for 47 muscles using Mercuri's classification. Whole-body scans were obtained with a mean in-room time of 29 min. Muscle changes consisted of internal bright signals of fatty replacement without severe retraction of the muscles' corpus. Findings were consistent with previous descriptions of spine extensors and pelvic girdle, but also provided new information on recurrent muscle changes particularly in the tongue and subscapularis muscle. Moreover thigh involvement was more heterogeneous than previously described, in terms of distribution across muscles as well as with respect to the overall clinical presentation. Whole-body MRI provides a very evocative description of muscle involvement in Pompe disease in adults. Copyright © 2011 Elsevier B.V. All rights reserved.

A pH/enzyme-responsive polymer film consisting of Eudragit FS 30 D and arabinoxylane as a potential material formulation for colon-specific drug delivery system.

PubMed

Rabito, Mirela Fulgencio; Reis, Adriano Valim; Freitas, Adonilson dos Reis; Tambourgi, Elias Basile; Cavalcanti, Osvaldo Albuquerque

2012-01-01

Polymer film based on pH-dependent Eudragit FS 30 D acrylic polymer in association with arabinoxylane, a polysaccharide issued from gum psyllium, was produced by way of solvent casting. Physical-chemical characterization of the polymer film samples was performed by means of thermogravimetry (TGA), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM). Furthermore, water-equilibrium swelling index (I(s)) and weight loss of the films in KCl buffer solution of pH 1.2, in KH(2)PO(4) buffer solution of pH 5.0, or in KH(2)PO(4) buffer solution of pH 5.0 consisting of 4% enzyme Pectinex 3X-L (w/v) were also carried out for the film characterization. No chemical interactions between the Eudragit FS 30 D and the arabinoxylane polymer chains were evidenced, thus suggesting that the film-forming polymer structure was obtained from a physical mixture of both polymers. The arabinoxylane-loader films showed a more pronounced weight loss after their immersion in buffer solution containing enzyme Pectinex 3X-L. The introduction of the arabinoxylane makes the film more susceptible to undergo an enzymatic degradation. This meant that the enzyme-dependent propriety issued from the arabinoxylane has been imprinted into the film formulation. This type of polymer film is an interesting system for applications in colon-specific drug delivery system.

Automatic three-dimensional rib centerline extraction from CT scans for enhanced visualization and anatomical context

NASA Astrophysics Data System (ADS)

Ramakrishnan, Sowmya; Alvino, Christopher; Grady, Leo; Kiraly, Atilla

2011-03-01

We present a complete automatic system to extract 3D centerlines of ribs from thoracic CT scans. Our rib centerline system determines the positional information for the rib cage consisting of extracted rib centerlines, spinal canal centerline, pairing and labeling of ribs. We show an application of this output to produce an enhanced visualization of the rib cage by the method of Kiraly et al., in which the ribs are digitally unfolded along their centerlines. The centerline extraction consists of three stages: (a) pre-trace processing for rib localization, (b) rib centerline tracing, and (c) post-trace processing to merge the rib traces. Then we classify ribs from non-ribs and determine anatomical rib labeling. Our novel centerline tracing technique uses the Random Walker algorithm to segment the structural boundary of the rib in successive 2D cross sections orthogonal to the longitudinal direction of the ribs. Then the rib centerline is progressively traced along the rib using a 3D Kalman filter. The rib centerline extraction framework was evaluated on 149 CT datasets with varying slice spacing, dose, and under a variety of reconstruction kernels. The results of the evaluation are presented. The extraction takes approximately 20 seconds on a modern radiology workstation and performs robustly even in the presence of partial volume effects or rib pathologies such as bone metastases or fractures, making the system suitable for assisting clinicians in expediting routine rib reading for oncology and trauma applications.

Automated Visibility Measurements with a Horizon Scanning Imager. Volume 1. Technical Discussion

DTIC Science & Technology

1990-12-01

environment, if one difficult. In the case of many relatively simplistic "rule assumes that the measured values of Cr are consistently following...report unless contractual obligations or notices on a specific document requires that it be returned. REPORT DOCUMENTATION PAGE Approved OMB No. 0704-0188...control computer from the original Zenith Z-248 incentive being that the sooner one identifies the class desktop to the Texas Micro Systems (TMI) design

Microencapsulation of Polyfunctional Amines for Self-Healing of Epoxy-Based Composites

DTIC Science & Technology

2008-01-01

MICROENCAPSULATION OF POLYFUNCTIONAL AMINES FOR SELF-HEALING OF EPOXY-BASED COMPOSITES David A. McIlroy*§, Ben J. Blaiszik,¥ Paul V. Braun... microcapsules containing an amine hardener (DEH-52, Dow Chemical) for use as the hardener in a 2-part epoxy healing system consisting of epoxy...microscope. Scanning electron microscopy was performed on a Philips XL30 ESEM-FEG instrument. Microencapsulation Procedure. 10 g of a 2:1 v/v

Virtual Reality Model of the Three-Dimensional Anatomy of the Cavernous Sinus Based on a Cadaveric Image and Dissection.

PubMed

Qian, Zeng-Hui; Feng, Xu; Li, Yang; Tang, Ke

2018-01-01

Studying the three-dimensional (3D) anatomy of the cavernous sinus is essential for treating lesions in this region with skull base surgeries. Cadaver dissection is a conventional method that has insurmountable flaws with regard to understanding spatial anatomy. The authors' research aimed to build an image model of the cavernous sinus region in a virtual reality system to precisely, individually and objectively elucidate the complete and local stereo-anatomy. Computed tomography and magnetic resonance imaging scans were performed on 5 adult cadaver heads. Latex mixed with contrast agent was injected into the arterial system and then into the venous system. Computed tomography scans were performed again following the 2 injections. Magnetic resonance imaging scans were performed again after the cranial nerves were exposed. Image data were input into a virtual reality system to establish a model of the cavernous sinus. Observation results of the image models were compared with those of the cadaver heads. Visualization of the cavernous sinus region models built using the virtual reality system was good for all the cadavers. High resolutions were achieved for the images of different tissues. The observed results were consistent with those of the cadaver head. The spatial architecture and modality of the cavernous sinus were clearly displayed in the 3D model by rotating the model and conveniently changing its transparency. A 3D virtual reality model of the cavernous sinus region is helpful for globally and objectively understanding anatomy. The observation procedure was accurate, convenient, noninvasive, and time and specimen saving.

Video-rate scanning two-photon excitation fluorescence microscopy and ratio imaging with cameleons.

PubMed Central

Fan, G Y; Fujisaki, H; Miyawaki, A; Tsay, R K; Tsien, R Y; Ellisman, M H

1999-01-01

A video-rate (30 frames/s) scanning two-photon excitation microscope has been successfully tested. The microscope, based on a Nikon RCM 8000, incorporates a femtosecond pulsed laser with wavelength tunable from 690 to 1050 nm, prechirper optics for laser pulse-width compression, resonant galvanometer for video-rate point scanning, and a pair of nonconfocal detectors for fast emission ratioing. An increase in fluorescent emission of 1.75-fold is consistently obtained with the use of the prechirper optics. The nonconfocal detectors provide another 2.25-fold increase in detection efficiency. Ratio imaging and optical sectioning can therefore be performed more efficiently without confocal optics. Faster frame rates, at 60, 120, and 240 frames/s, can be achieved with proportionally reduced scan lines per frame. Useful two-photon images can be acquired at video rate with a laser power as low as 2.7 mW at specimen with the genetically modified green fluorescent proteins. Preliminary results obtained using this system confirm that the yellow "cameleons" exhibit similar optical properties as under one-photon excitation conditions. Dynamic two-photon images of cardiac myocytes and ratio images of yellow cameleon-2.1, -3.1, and -3.1nu are also presented. PMID:10233058

Wide-field reflective scanning optical systems

NASA Technical Reports Server (NTRS)

Abel, I. R.

1973-01-01

Catoptric optical scanning system provides relatively fast line-scan rate for two-dimensional coverage. Rapid scan rates require low focal ratios between components and smallest possible masses. System is relatively free from monochromatic defects and chromatic aberrations.

Coded aperture coherent scatter spectral imaging for assessment of breast cancers: an ex-vivo demonstration

NASA Astrophysics Data System (ADS)

Spencer, James R.; Carter, Joshua E.; Leung, Crystal K.; McCall, Shannon J.; Greenberg, Joel A.; Kapadia, Anuj J.

2017-03-01

A Coded Aperture Coherent Scatter Spectral Imaging (CACSSI) system was developed in our group to differentiate cancer and healthy tissue in the breast. The utility of the experimental system was previously demonstrated using anthropomorphic breast phantoms and breast biopsy specimens. Here we demonstrate CACSSI utility in identifying tumor margins in real time using breast lumpectomy specimens. Fresh lumpectomy specimens were obtained from Surgical Pathology with the suspected cancerous area designated on the specimen. The specimens were scanned using CACSSI to obtain spectral scatter signatures at multiple locations within the tumor and surrounding tissue. The spectral reconstructions were matched with literature form-factors to classify the tissue as cancerous or non-cancerous. The findings were then compared against pathology reports to confirm the presence and location of the tumor. The system was found to be capable of consistently differentiating cancerous and healthy regions in the breast with spatial resolution of 5 mm. Tissue classification results from the scanned specimens could be correlated with pathology results. We now aim to develop CACSSI as a clinical imaging tool to aid breast cancer assessment and other diagnostic purposes.

Conductivity map from scanning tunneling potentiometry.

PubMed

Zhang, Hao; Li, Xianqi; Chen, Yunmei; Durand, Corentin; Li, An-Ping; Zhang, X-G

2016-08-01

We present a novel method for extracting two-dimensional (2D) conductivity profiles from large electrochemical potential datasets acquired by scanning tunneling potentiometry of a 2D conductor. The method consists of a data preprocessing procedure to reduce/eliminate noise and a numerical conductivity reconstruction. The preprocessing procedure employs an inverse consistent image registration method to align the forward and backward scans of the same line for each image line followed by a total variation (TV) based image restoration method to obtain a (nearly) noise-free potential from the aligned scans. The preprocessed potential is then used for numerical conductivity reconstruction, based on a TV model solved by accelerated alternating direction method of multiplier. The method is demonstrated on a measurement of the grain boundary of a monolayer graphene, yielding a nearly 10:1 ratio for the grain boundary resistivity over bulk resistivity.

Luminescence imaging of water during uniform-field irradiation by spot scanning proton beams

NASA Astrophysics Data System (ADS)

Komori, Masataka; Sekihara, Eri; Yabe, Takuya; Horita, Ryo; Toshito, Toshiyuki; Yamamoto, Seiichi

2018-06-01

Luminescence was found during pencil-beam proton irradiation to water phantom and range could be estimated from the luminescence images. However, it is not yet clear whether the luminescence imaging is applied to the uniform fields made of spot-scanning proton-beam irradiations. For this purpose, imaging was conducted for the uniform fields having spread out Bragg peak (SOBP) made by spot scanning proton beams. We designed six types of the uniform fields with different ranges, SOBP widths and irradiation fields. One of the designed fields was irradiated to water phantom and a cooled charge coupled device camera was used to measure the luminescence image during irradiations. We estimated the ranges, field widths, and luminescence intensities from the luminescence images and compared those with the dose distribution calculated by a treatment planning system. For all types of uniform fields, we could obtain clear images of the luminescence showing the SOBPs. The ranges and field widths evaluated from the luminescence were consistent with those of the dose distribution calculated by a treatment planning system within the differences of  ‑4 mm and  ‑11 mm, respectively. Luminescence intensities were almost proportional to the SOBP widths perpendicular to the beam direction. The luminescence imaging could be applied to uniform fields made of spot scanning proton beam irradiations. Ranges and widths of the uniform fields with SOBP could be estimated from the images. The luminescence imaging is promising for the range and field width estimations in proton therapy.

Dynamic electronic collimation method for 3-D catheter tracking on a scanning-beam digital x-ray system

PubMed Central

Dunkerley, David A. P.; Slagowski, Jordan M.; Funk, Tobias; Speidel, Michael A.

2017-01-01

Abstract. Scanning-beam digital x-ray (SBDX) is an inverse geometry x-ray fluoroscopy system capable of tomosynthesis-based 3-D catheter tracking. This work proposes a method of dose-reduced 3-D catheter tracking using dynamic electronic collimation (DEC) of the SBDX scanning x-ray tube. This is achieved through the selective deactivation of focal spot positions not needed for the catheter tracking task. The technique was retrospectively evaluated with SBDX detector data recorded during a phantom study. DEC imaging of a catheter tip at isocenter required 340 active focal spots per frame versus 4473 spots in full field-of-view (FOV) mode. The dose-area product (DAP) and peak skin dose (PSD) for DEC versus full FOV scanning were calculated using an SBDX Monte Carlo simulation code. The average DAP was reduced to 7.8% of the full FOV value, consistent with the relative number of active focal spots (7.6%). For image sequences with a moving catheter, PSD was 33.6% to 34.8% of the full FOV value. The root-mean-squared-deviation between DEC-based 3-D tracking coordinates and full FOV 3-D tracking coordinates was less than 0.1 mm. The 3-D distance between the tracked tip and the sheath centerline averaged 0.75 mm. DEC is a feasible method for dose reduction during SBDX 3-D catheter tracking. PMID:28439521

Quick-EXAFS setup at the SuperXAS beamline for in situ X-ray absorption spectroscopy with 10 ms time resolution

PubMed Central

Müller, Oliver; Nachtegaal, Maarten; Just, Justus; Lützenkirchen-Hecht, Dirk; Frahm, Ronald

2016-01-01

The quick-EXAFS (QEXAFS) method adds time resolution to X-ray absorption spectroscopy (XAS) and allows dynamic structural changes to be followed. A completely new QEXAFS setup consisting of monochromator, detectors and data acquisition system is presented, as installed at the SuperXAS bending-magnet beamline at the Swiss Light Source (Paul Scherrer Institute, Switzerland). The monochromator uses Si(111) and Si(311) channel-cut crystals mounted on one crystal stage, and remote exchange allows an energy range from 4.0 keV to 32 keV to be covered. The spectral scan range can be electronically adjusted up to several keV to cover multiple absorption edges in one scan. The determination of the Bragg angle close to the position of the crystals allows high-accuracy measurements. Absorption spectra can be acquired with fast gridded ionization chambers at oscillation frequencies of up to 50 Hz resulting in a time resolution of 10 ms, using both scan directions of each oscillation period. The carefully developed low-noise detector system yields high-quality absorption data. The unique setup allows both state-of-the-art QEXAFS and stable step-scan operation without the need to exchange whole monochromators. The long-term stability of the Bragg angle was investigated and absorption spectra of reference materials as well as of a fast chemical reaction demonstrate the overall capabilities of the new setup. PMID:26698072

Quick-EXAFS setup at the SuperXAS beamline for in situ X-ray absorption spectroscopy with 10 ms time resolution.

PubMed

Müller, Oliver; Nachtegaal, Maarten; Just, Justus; Lützenkirchen-Hecht, Dirk; Frahm, Ronald

2016-01-01

The quick-EXAFS (QEXAFS) method adds time resolution to X-ray absorption spectroscopy (XAS) and allows dynamic structural changes to be followed. A completely new QEXAFS setup consisting of monochromator, detectors and data acquisition system is presented, as installed at the SuperXAS bending-magnet beamline at the Swiss Light Source (Paul Scherrer Institute, Switzerland). The monochromator uses Si(111) and Si(311) channel-cut crystals mounted on one crystal stage, and remote exchange allows an energy range from 4.0 keV to 32 keV to be covered. The spectral scan range can be electronically adjusted up to several keV to cover multiple absorption edges in one scan. The determination of the Bragg angle close to the position of the crystals allows high-accuracy measurements. Absorption spectra can be acquired with fast gridded ionization chambers at oscillation frequencies of up to 50 Hz resulting in a time resolution of 10 ms, using both scan directions of each oscillation period. The carefully developed low-noise detector system yields high-quality absorption data. The unique setup allows both state-of-the-art QEXAFS and stable step-scan operation without the need to exchange whole monochromators. The long-term stability of the Bragg angle was investigated and absorption spectra of reference materials as well as of a fast chemical reaction demonstrate the overall capabilities of the new setup.

New Research by CCD Scanning for Comets and Asteroids

NASA Technical Reports Server (NTRS)

Gehrels, Tom; McMillan, Robert S.

1997-01-01

The purpose of Spacewatch is to explore the various populations of small objects within the solar system. Spacewatch provides data for studies of comets and asteroids, finds potential targets for space missions, and provides information on the environmental problem of possible impacts. Moving objects are discovered by scanning the sky with charge-coupled devices (CCDs) on the 0.9-meter Spacewatch Telescope of the University of Arizona on Kitt Peak. Each Spacewatch scan consists of three drift scan passes over an area of sky using a CCD filtered to a bandpass of 0.5-1.0 microns (approximately V+R+I with peak sensitivity at 0.7 micron). The effective exposure time for each pass is 143 seconds multiplied by the secant of the declination. We have been finding some 30,000 new asteroids per year and applying their statistics to the study of the collisional history of the solar system. As of the end of the observing run of Nov. 1997, Spacewatch had found a total of 153 Near-Earth Asteroids (NEAs) and 8 new comets since the project began in the 1980s, and had recovered one lost comet. The total number of NEAs found by Spacewatch big enough to be hazardous if they were to impact the Earth is 36. Spacewatch is also efficient in recovery of known comets and has detected and reported positions for more than 137,000 asteroids, mostly new ones in the main belt, including more than 16,000 asteroids designated by the Minor Planet Center (MPC).

The Nimbus 6 data catalog. Volume 6: Data orbits 4339 through 5155. [from May through June 1976

NASA Technical Reports Server (NTRS)

1977-01-01

Satellite operations from launch through 14 July (orbit 425) consisted of engineering evaluation of all spacecraft systems. As a result of that effort, data reception, accountability and processing were intermittent during that period. During orbit 4905 (12 June), Nimbus 6 successfully completed one year operations. A summary of the documentation for each Nimbus 6 Data Catalog volume is presented. The pitch of the Nimbus 6 satellite has been made to alternate between +2.0 degrees, +0.6 degrees, and 0.0 degrees since launch. A positive pitch angle of 0.6 degrees moves the nadir-looking position 11.5 kilometers ahead of the subsatellite point. A positive pitch angle of 2.0 degrees moves the nadir-looking position 38.3 kilometers ahead of the subsatellite point. At these pitch angles, a scanner-type instrument no longer scans the earth along a great circle arc through the subpoint, but scans along the small circle formed by the intersection of the scan plane with the earth. Since the plane of the small circle is tilted with respect to the nominal scan plane, points on the arc are displaced farther from the great circle as the scan angle increases. As noted above, a pitch angle of 0.6 degrees causes a displacement of 11.5 kilometers at nadir, but when the scanner turns 45 degrees away from nadir the displacement increases slightly to 12.8 kilometers. Similarly, for a 2.0 degree pitch the displacement is 38.3 kilometers at nadir and increases to 42.6 kilometers at a 45 degree scan angle. Thus, although the instrument records in lines normal to the orbit plane (in the absence of yaw) the perpendicular displacement from the perfect-attitude scan line is not uniform across the scan line.

Method for dose-reduced 3D catheter tracking on a scanning-beam digital x-ray system using dynamic electronic collimation

NASA Astrophysics Data System (ADS)

Dunkerley, David A. P.; Funk, Tobias; Speidel, Michael A.

2016-03-01

Scanning-beam digital x-ray (SBDX) is an inverse geometry x-ray fluoroscopy system capable of tomosynthesis-based 3D catheter tracking. This work proposes a method of dose-reduced 3D tracking using dynamic electronic collimation (DEC) of the SBDX scanning x-ray tube. Positions in the 2D focal spot array are selectively activated to create a regionof- interest (ROI) x-ray field around the tracked catheter. The ROI position is updated for each frame based on a motion vector calculated from the two most recent 3D tracking results. The technique was evaluated with SBDX data acquired as a catheter tip inside a chest phantom was pulled along a 3D trajectory. DEC scans were retrospectively generated from the detector images stored for each focal spot position. DEC imaging of a catheter tip in a volume measuring 11.4 cm across at isocenter required 340 active focal spots per frame, versus 4473 spots in full-FOV mode. The dose-area-product (DAP) and peak skin dose (PSD) for DEC versus full field-of-view (FOV) scanning were calculated using an SBDX Monte Carlo simulation code. DAP was reduced to 7.4% to 8.4% of the full-FOV value, consistent with the relative number of active focal spots (7.6%). For image sequences with a moving catheter, PSD was 33.6% to 34.8% of the full-FOV value. The root-mean-squared-deviation between DEC-based 3D tracking coordinates and full-FOV 3D tracking coordinates was less than 0.1 mm. The 3D distance between the tracked tip and the sheath centerline averaged 0.75 mm. Dynamic electronic collimation can reduce dose with minimal change in tracking performance.

WINCS-BASED WIRELESS ELECTROCHEMICAL MONITORING OF SEROTONIN (5-HT) USING FAST-SCAN CYCLIC VOLTAMMETRY: PROOF OF PRINCIPLE

PubMed Central

Griessenauer, Christoph J.; Chang, Su-Youne; Tye, Susannah J.; Kimble, Christopher J.; Bennet, Kevin E.; Garris, Paul A.; Lee, Kendall H.

2010-01-01

Object We previously reported the development of a Wireless Instantaneous Neurotransmitter Concentration System (WINCS) for measuring dopamine and suggested that this technology may be useful for evaluating deep brain stimulation (DBS)-related neuromodulatory effects on neurotransmitter systems. WINCS supports fast-scan cyclic voltammetry (FSCV) at a carbon-fiber microelectrode (CFM) for real-time, spatially resolved neurotransmitter measurements. The FSCV parameters used to establish WINCS dopamine measurements are not suitable for serotonin, a neurotransmitter implicated in depression, because they lead to CFM fouling and a loss of sensitivity. Here, we incorporate into WINCS a previously described N-shaped waveform applied at a high scan rate to establish wireless serotonin monitoring. Methods FSCV optimized for the detection of serotonin consisted of an N-shaped waveform scanned linearly from a resting potential of, in V, +0.2 to +1.0, then to −0.1 and back to +0.2 at a rate of 1000 V/s. Proof of principle tests included flow injection analysis and electrically evoked serotonin release in the dorsal raphe nucleus of rat brain slices. Results Flow cell injection analysis demonstrated that the N waveform applied at a scan rate of 1000 V/s significantly reduced serotonin fouling of the CFM, relative to that observed with FSCV parameters for dopamine. In brain slices, WINCS reliably detected sub-second serotonin release in the dorsal raphe nucleus evoked by local high-frequency stimulation. Conclusion WINCS supported high-fidelity wireless serotonin monitoring by FSCV at a CFM. In the future such measurements of serotonin in large animal models and in humans may help to establish the mechanism of DBS for psychiatric disease. PMID:20415521

Comprehensive clinical commissioning and validation of the RayStation treatment planning system for proton therapy with active scanning and passive treatment techniques.

PubMed

Bäumer, C; Geismar, D; Koska, B; Kramer, P H; Lambert, J; Lemke, M; Plaude, S; Pschichholz, L; Qamhiyeh, S; Schiemann, A; Timmermann, B; Vermeren, X

2017-11-01

To commission the treatment planning system (TPS) RayStation for proton therapy including beam models for spot scanning and for uniform scanning. Tests consist of procedures from ESTRO booklet number 7, the German DIN for constancy checks of TPSs, and extra tests checking the dose perturbation function. The dose distributions within patients were verified in silico by a comparison of 65 clinical treatment plans with the TPS XiO. Dose-volume parameters, dose differences, and three-dimensional gamma-indices serve as measures of similarity. The monthly constancy checks of Raystation have been automatized with a script. The basic functionality of the software complies with ESTRO booklet number 7. For a few features minor enhancements are suggested. The dose distribution in RayStation agrees with the calculation in XiO. This is supported by a gamma-index (3mm/3%) pass rate of >98.9% (median over 59 plans) for the volume within the 20% isodose line and a difference of <0.3% of V 95 of the PTV (median over 59 plans). If spot scanning is used together with a range shifter, the dose level calculated by RayStation can be off by a few percent. RayStation can be used for the creation of clinical proton treatment plans. Compared to XiO RayStation has an improved modelling of the lateral dose fall-off in passively delivered fields. For spot scanning fields with range shifter blocks an empirical adjustment of monitor units is required. The computation of perturbed doses also allows the evaluation of the robustness of a treatment plan. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Computer Vision Malaria Diagnostic Systems-Progress and Prospects.

PubMed

Pollak, Joseph Joel; Houri-Yafin, Arnon; Salpeter, Seth J

2017-01-01

Accurate malaria diagnosis is critical to prevent malaria fatalities, curb overuse of antimalarial drugs, and promote appropriate management of other causes of fever. While several diagnostic tests exist, the need for a rapid and highly accurate malaria assay remains. Microscopy and rapid diagnostic tests are the main diagnostic modalities available, yet they can demonstrate poor performance and accuracy. Automated microscopy platforms have the potential to significantly improve and standardize malaria diagnosis. Based on image recognition and machine learning algorithms, these systems maintain the benefits of light microscopy and provide improvements such as quicker scanning time, greater scanning area, and increased consistency brought by automation. While these applications have been in development for over a decade, recently several commercial platforms have emerged. In this review, we discuss the most advanced computer vision malaria diagnostic technologies and investigate several of their features which are central to field use. Additionally, we discuss the technological and policy barriers to implementing these technologies in low-resource settings world-wide.

Visible light spectral domain optical coherence microscopy system for ex vivo imaging

NASA Astrophysics Data System (ADS)

Lichtenegger, Antonia; Harper, Danielle J.; Augustin, Marco; Eugui, Pablo; Fialová, Stanislava; Woehrer, Adelheid; Hitzenberger, Christoph K.; Baumann, Bernhard

2017-02-01

A visible light spectral domain optical coherence microscopy system operating in the wavelength range of 450-680 nm was developed. The resulting large wavelength range of 230 nm enabled an ultrahigh axial resolution of 0.88μm in tissue. The setup consisted of a Michelson interferometer combined with a homemade spectrometer with a spectral resolution of 0.03 nm. Scanning of 1 x 1 mm2 and 0.5 x 0.5 mm2 areas was performed by an integrated microelectromechanical mirror. After scanning the light beam is focused onto the tissue by a commercial objective with a 10 x magnification, resulting in a transverse resolution of 2 μm . Specification measurements showed that a -89 dB sensitivity with a 24 dB/mm roll-off could be achieved with the system. First of all the capabilities of the system were tested by investigating millimeter paper, tape and the USAF (US Air Force) 1951 resolution test target. Finally cerebral tissues from non-pathological and Alzheimer's disease affected brains were investigated. The results showed that structures, such as white and gray matter, could be distinguished. Furthermore a first effort was made to differentiate Alzheimer's disease from healthy brain tissue.

Optical signal processing

NASA Astrophysics Data System (ADS)

Vanderlugt, A.

1993-07-01

A quasi-realtime adaptive processing system was used to correct the multipath distortion found in wideband digital radios. The measured power spectral density of the input signal was used to adaptively select one of eight equalization filters which reduce the residual distortion to less than 3.6 dB even for the most severe channel distortion. A related adaptive system was used for signal excision in which we removed narrowband interference from wideband signals with minimum signal distortion. An 8x8 acousto-optic switch in a multimode fiber-optic system was built. Insertion loss is approximately 2-4 dB, signal-to-crosstalk ratio is better than 25 dB, and the reconfiguration time is 880 nsec. Short pulses were detected by using the Fresnel transform. Pulses as short as the theoretical limit of 20 nanoseconds were detected for this system, and separated by as little as 60 nanoseconds or by as much as 17 nanoseconds. All possible acousto-optic scanning configurations were considered and classified into four basic types. A consistent set of design relationships for each of the scanning configurations was developed and presented in both tabular and graphic forms from which a preliminary design is obtained.

Image dissector camera system study

NASA Technical Reports Server (NTRS)

Howell, L.

1984-01-01

Various aspects of a rendezvous and docking system using an image dissector detector as compared to a GaAs detector were discussed. Investigation into a gimbled scanning system is also covered and the measured video response curves from the image dissector camera are presented. Rendezvous will occur at ranges greater than 100 meters. The maximum range considered was 1000 meters. During docking, the range, range-rate, angle, and angle-rate to each reflector on the satellite must be measured. Docking range will be from 3 to 100 meters. The system consists of a CW laser diode transmitter and an image dissector receiver. The transmitter beam is amplitude modulated with three sine wave tones for ranging. The beam is coaxially combined with the receiver beam. Mechanical deflection of the transmitter beam, + or - 10 degrees in both X and Y, can be accomplished before or after it is combined with the receiver beam. The receiver will have a field-of-view (FOV) of 20 degrees and an instantaneous field-of-view (IFOV) of two milliradians (mrad) and will be electronically scanned in the image dissector. The increase in performance obtained from the GaAs photocathode is not needed to meet the present performance requirements.

Multidirectional four-dimensional shape measurement system

NASA Astrophysics Data System (ADS)

Lenar, Janusz; Sitnik, Robert; Witkowski, Marcin

2012-03-01

Currently, a lot of different scanning techniques are used for 3D imaging of human body. Most of existing systems are based on static registration of internal structures using MRI or CT techniques as well as 3D scanning of outer surface of human body by laser triangulation or structured light methods. On the other hand there is an existing mature 4D method based on tracking in time the position of retro-reflective markers attached to human body. There are two main drawbacks of this solution: markers are attached to skin (no real skeleton movement is registered) and it gives (x, y, z, t) coordinates only in those points (not for the whole surface). In this paper we present a novel multidirectional structured light measurement system that is capable of measuring 3D shape of human body surface with frequency reaching 60Hz. The developed system consists of two spectrally separated and hardware-synchronized 4D measurement heads. The principle of the measurement is based on single frame analysis. Projected frame is composed from sine-modulated intensity pattern and a special stripe allowing absolute phase measurement. Several different geometrical set-ups will be proposed depending on type of movements that are to be registered.

Natural Crack Sizing Based on Eddy Current Image and Electromagnetic Field Analyses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Endo, H.; Uchimoto, T.; Takagi, T.

2006-03-06

An eddy current testing (ECT) system with multi-coil type probes is applied to size up cracks fabricated on austenite stainless plates. We have developed muti-channel ECT system to produce data as digital images. The probes consist of transmit-receive type sensors as elements to classify crack directions, working as two scan direction modes simultaneously. Template matching applied to the ECT images determines regions of interest in sizing up cracks. Finite element based inversion sizes up the crack depth from the measured ECT signal. The present paper demonstrates this approach for fatigue crack and stress corrosion cracking.

Development of a Dynamic Biomechanical Model for Load Carriage: Phase 4, Part C2: Assessment of Pressure Measurement Systems on Curved Surfaces for the Dynamic Biomechanical Model of Human Load Carriage

DTIC Science & Technology

2005-08-01

excellente justesse comparativement au F-Scan® pendant les essais sur le modèle de hanche. Les deux systèmes présentaient un certain degré de variation...in appendix C. The experimental design consisted of three steps (See Figure 1). Two were undertaken using a physical model for the shoulder in order...increase in accuracy error compared to Table 1 suggests that the current software for the XSENSOR® system is not designed to compensate for errors

Eddy Current System for Material Inspection and Flaw Visualization

NASA Technical Reports Server (NTRS)

Bachnak, R.; King, S.; Maeger, W.; Nguyen, T.

2007-01-01

Eddy current methods have been successfully used in a variety of non-destructive evaluation applications including detection of cracks, measurements of material thickness, determining metal thinning due to corrosion, measurements of coating thickness, determining electrical conductivity, identification of materials, and detection of corrosion in heat exchanger tubes. This paper describes the development of an eddy current prototype that combines positional and eddy-current data to produce a C-scan of tested material. The preliminary system consists of an eddy current probe, a position tracking mechanism, and basic data visualization capability. Initial test results of the prototype are presented in this paper.

Development of scanning holographic display using MEMS SLM

NASA Astrophysics Data System (ADS)

Takaki, Yasuhiro

2016-10-01

Holography is an ideal three-dimensional (3D) display technique, because it produces 3D images that naturally satisfy human 3D perception including physiological and psychological factors. However, its electronic implementation is quite challenging because ultra-high resolution is required for display devices to provide sufficient screen size and viewing zone. We have developed holographic display techniques to enlarge the screen size and the viewing zone by use of microelectromechanical systems spatial light modulators (MEMS-SLMs). Because MEMS-SLMs can generate hologram patterns at a high frame rate, the time-multiplexing technique is utilized to virtually increase the resolution. Three kinds of scanning systems have been combined with MEMS-SLMs; the screen scanning system, the viewing-zone scanning system, and the 360-degree scanning system. The screen scanning system reduces the hologram size to enlarge the viewing zone and the reduced hologram patterns are scanned on the screen to increase the screen size: the color display system with a screen size of 6.2 in. and a viewing zone angle of 11° was demonstrated. The viewing-zone scanning system increases the screen size and the reduced viewing zone is scanned to enlarge the viewing zone: a screen size of 2.0 in. and a viewing zone angle of 40° were achieved. The two-channel system increased the screen size to 7.4 in. The 360-degree scanning increases the screen size and the reduced viewing zone is scanned circularly: the display system having a flat screen with a diameter of 100 mm was demonstrated, which generates 3D images viewed from any direction around the flat screen.

Discrete pre-processing step effects in registration-based pipelines, a preliminary volumetric study on T1-weighted images.

PubMed

Muncy, Nathan M; Hedges-Muncy, Ariana M; Kirwan, C Brock

2017-01-01

Pre-processing MRI scans prior to performing volumetric analyses is common practice in MRI studies. As pre-processing steps adjust the voxel intensities, the space in which the scan exists, and the amount of data in the scan, it is possible that the steps have an effect on the volumetric output. To date, studies have compared between and not within pipelines, and so the impact of each step is unknown. This study aims to quantify the effects of pre-processing steps on volumetric measures in T1-weighted scans within a single pipeline. It was our hypothesis that pre-processing steps would significantly impact ROI volume estimations. One hundred fifteen participants from the OASIS dataset were used, where each participant contributed three scans. All scans were then pre-processed using a step-wise pipeline. Bilateral hippocampus, putamen, and middle temporal gyrus volume estimations were assessed following each successive step, and all data were processed by the same pipeline 5 times. Repeated-measures analyses tested for a main effects of pipeline step, scan-rescan (for MRI scanner consistency) and repeated pipeline runs (for algorithmic consistency). A main effect of pipeline step was detected, and interestingly an interaction between pipeline step and ROI exists. No effect for either scan-rescan or repeated pipeline run was detected. We then supply a correction for noise in the data resulting from pre-processing.

SU-F-T-403: Impact of Dose Reduction for Simulation CT On Radiation Therapy Treatment Planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liang, Q; Shah, P; Li, S

Purpose: To investigate the feasibility of applying ALARA principles to current treatment planning CT scans. The study aims to quantitatively verify lower dose scans does not alter treatment planning. Method: Gammex 467 tissue characterization phantom with inserts of 14 different materials was scanned at seven different mA levels (30∼300 mA). CT numbers of different inserts were measured. Auto contouring for bone and lung in treatment planning system (Pinnacle) was used to evaluate the effect of CT number accuracy from treatment planning aspect, on the 30 and 300 mA-scanned images. A head CT scan intended for a 3D whole brain radiationmore » treatment was evaluated. Dose calculations were performed on normal scanned images using clinical protocol (120 kVP, Smart mA, maximum 291 mA), and the images with added simulating noise mimicking a 70 mA scan. Plan parameters including isocenter, beam arrangements, block shapes, dose grid size and resolution, and prescriptions were kept the same for these two plans. The calculated monitor units (MUs) for these two plans were compared. Results: No significant degradation of CT number accuracy was found at lower dose levels from both the phantom scans, and the patient images with added noise. The CT numbers kept consistent when mA is higher than 60 mA. The auto contoured volumes for lung and cortical bone show 0.3% and 0.12% of differences between 30 mA and 300 mA respectively. The two forward plans created on regular and low dose images gave the same calculated MU, and 98.3% of points having <1% of dose difference. Conclusion: Both phantom and patient studies quantitatively verified low dose CT provides similar quality for treatment planning at 20–25% of regular scan dose. Therefore, there is the potential to optimize simulation CT scan protocol to fulfil the ALARA principle and limit unnecessary radiation exposure to non-targeted tissues.« less

SU-G-JeP2-13: Spatial Accuracy Evaluation for Real-Time MR Guided Radiation Therapy Using a Novel Large-Field MRI Distortion Phantom

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antolak, A; Bayouth, J; Bosca, R

Purpose: Evaluate a large-field MRI phantom for assessment of geometric distortion in whole-body MRI for real-time MR guided radiation therapy. Methods: A prototype CIRS large-field MRI distortion phantom consisting of a PMMA cylinder (33 cm diameter, 30 cm length) containing a 3D-printed orthogonal grid (3 mm diameter rods, 20 mm apart), was filled with 6 mM NiCl{sub 2} and 30 mM NaCl solution. The phantom was scanned at 1.5T and 3.0T on a GE HDxt and Discovery MR750, respectively, and at 0.35T on a ViewRay system. Scans were obtained with and without 3D distortion correction to demonstrate the impact ofmore » such corrections. CT images were used as a reference standard for analysis of geometric distortion, as determined by a fully automated gradient-search method developed in Matlab. Results: 1,116 grid points distributed throughout a cylindrical volume 28 cm in diameter and 16 cm in length were identified and analyzed. With 3D distortion correction, average/maximum displacements for the 1.5, 3.0, and 0.35T systems were 0.84/2.91, 1.00/2.97, and 0.95/2.37 mm, respectively. The percentage of points with less than (1.0, 1.5, 2.0 mm) total displacement were (73%, 92%, 97%), (54%, 85%, 97%), and (55%, 90%, 99%), respectively. A reduced scan volume of 20 × 20 × 10 cm{sup 3} (representative of a head and neck scan volume) consisting of 420 points was also analyzed. In this volume, the percentage of points with less than (1.0, 1.5, 2.0 mm) total displacement were (90%, 99%, 100%), (63%, 95%, 100%), and (75%, 96%, 100%), respectively. Without 3D distortion correction, average/maximum displacements were 1.35/3.67, 1.67/4.46, and 1.51/3.89 mm, respectively. Conclusion: The prototype large-field MRI distortion phantom and developed software provide a thorough assessment of 3D spatial distortions in MRI. The distortions measured were acceptable for RT applications, both for the high field strengths and the system configuration developed by ViewRay.« less

A flexible 3D laser scanning system using a robotic arm

NASA Astrophysics Data System (ADS)

Fei, Zixuan; Zhou, Xiang; Gao, Xiaofei; Zhang, Guanliang

2017-06-01

In this paper, we present a flexible 3D scanning system based on a MEMS scanner mounted on an industrial arm with a turntable. This system has 7-degrees of freedom and is able to conduct a full field scan from any angle, suitable for scanning object with the complex shape. The existing non-contact 3D scanning system usually uses laser scanner that projects fixed stripe mounted on the Coordinate Measuring Machine (CMM) or industrial robot. These existing systems can't perform path planning without CAD models. The 3D scanning system presented in this paper can scan the object without CAD models, and we introduced this path planning method in the paper. We also propose a practical approach to calibrating the hand-in-eye system based on binocular stereo vision and analyzes the errors of the hand-eye calibration.

TDRS-L Pre-Launch Press Conference

NASA Image and Video Library

2014-01-21

CAPE CANAVERAL, Fla. – During a news conference at NASA's Kennedy Space Center in Florida, agency and contractor officials discussed preparations for the launch of NASA's Tracking and Data Relay Satellite, or TDRS-L, spacecraft. Participants included Clay Flinn, launch weather officer for the 45th Weather Squadron at Cape Canaveral Air Force Station, Fla. Seated behind Flinn is Andy Kopito, Civil Space Programs director for Boeing Space & Intelligence Systems in El Segundo, Calif. The TDRS-L spacecraft is the second of three new satellites designed to ensure vital operational continuity for NASA by expanding the lifespan of the Tracking and Data Relay Satellite System TDRSS fleet, which consists of eight satellites in geosynchronous orbit. The spacecraft provide tracking, telemetry, command and high bandwidth data return services for numerous science and human exploration missions orbiting Earth. These include NASA's Hubble Space Telescope and the International Space Station. TDRS-L has a high-performance solar panel designed for more spacecraft power to meet the growing S-band communications requirements. TDRSS is one of NASA Space Communication and Navigation’s SCaN three networks providing space communications to NASA’s missions. For more information more about TDRS-L, visit: http://www.nasa.gov/tdrs To learn more about SCaN, visit: www.nasa.gov/scan Photo credit: NASA/Frankie Martin

Potential errors in optical density measurements due to scanning side in EBT and EBT2 Gafchromic film dosimetry.

PubMed

Desroches, Joannie; Bouchard, Hugo; Lacroix, Frédéric

2010-04-01

The purpose of this study is to determine the effect on the measured optical density of scanning on either side of a Gafchromic EBT and EBT2 film using an Epson (Epson Canada Ltd., Toronto, Ontario) 10000XL flat bed scanner. Calibration curves were constructed using EBT2 film scanned in landscape orientation in both reflection and transmission mode on an Epson 10000XL scanner. Calibration curves were also constructed using EBT film. Potential errors due to an optical density difference from scanning the film on either side ("face up" or "face down") were simulated. Scanning the film face up or face down on the scanner bed while keeping the film angular orientation constant affects the measured optical density when scanning in reflection mode. In contrast, no statistically significant effect was seen when scanning in transmission mode. This effect can significantly affect relative and absolute dose measurements. As an application example, the authors demonstrate potential errors of 17.8% by inverting the film scanning side on the gamma index for 3%-3 mm criteria on a head and neck intensity modulated radiotherapy plan, and errors in absolute dose measurements ranging from 10% to 35% between 2 and 5 Gy. Process consistency is the key to obtaining accurate and precise results in Gafchromic film dosimetry. When scanning in reflection mode, care must be taken to place the film consistently on the same side on the scanner bed.

WE-DE-BRA-10: Development of a Novel Scanning Beam Low-Energy Intraoperative Radiation Therapy (SBIORT) System for Pancreatic Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wears, B; Mohiuddin, I; Flynn, R

2016-06-15

Purpose: Developing a compact collimator system and validating a 3D surface imaging module for a scanning beam low-energy x-ray radiation therapy (SBIORT) system that enables delivery of non-uniform radiation dose to targets with irregular shapes intraoperatively. Methods: SBIORT consists of a low energy x-ray source, a custom compact collimator module, a robotic arm, and a 3D surface imaging module. The 3D surface imaging system (structure sensor) is utilized for treatment planning and motion monitoring of the surgical cavity. SBIORT can deliver non-uniform dose distributions by dynamically moving the x-ray source assembly along optimal paths with various collimator apertures. The compactmore » collimator utilizes a dynamic shutter mechanism to form a variable square aperture. The accuracy and reproducibility of the collimator were evaluated using a high accuracy encoder and a high resolution camera platform. The dosimetrical characteristics of the collimator prototype were evaluated using EBT3 films with a Pantak Therapax unit. The accuracy and clinical feasibility of the 3D imaging system were evaluated using a phantom and a cadaver cavity. Results: The SBIORT collimator has a compact size: 66 mm diameter and 10 mm thickness with the maximum aperture of 20 mm. The mechanical experiment indicated the average accuracy of leaf position was 0.08 mm with a reproducibility of 0.25 mm at 95% confidence level. The dosimetry study indicated the collimator had a penumbra of 0.35 mm with a leaf transmission of 0.5%. 3D surface scans can be acquired in 5 seconds. The average difference between the acquired 3D surface and the ground truth is 1 mm with a standard deviation of 0.6 mm. Conclusion: This work demonstrates the feasibility of the compact collimator and 3D scanning system for the SBIORT. SBIORT is a way of delivering IORT with a compact system that requires minimum shielding of the procedure room. This research is supported by the University of Iowa Internal Funding Initiatives.« less

A novel constant-force scanning probe incorporating mechanical-magnetic coupled structures.

PubMed

Wang, Hongxi; Zhao, Jian; Gao, Renjing; Yang, Yintang

2011-07-01

A one-dimensional scanning probe with constant measuring force is designed and fabricated by utilizing the negative stiffness of the magnetic coupled structure, which mainly consists of the magnetic structure, the parallel guidance mechanism, and the pre-stressed spring. Based on the theory of material mechanics and the equivalent surface current model for computing the magnetic force, the analytical model of the scanning probe subjected to multi-forces is established, and the nonlinear relationship between the measuring force and the probe displacement is obtained. The practicability of introducing magnetic coupled structure in the constant-force probe is validated by the consistency of the results in numerical simulation and experiments.

A biological phantom for evaluation of CT image reconstruction algorithms

NASA Astrophysics Data System (ADS)

Cammin, J.; Fung, G. S. K.; Fishman, E. K.; Siewerdsen, J. H.; Stayman, J. W.; Taguchi, K.

2014-03-01

In recent years, iterative algorithms have become popular in diagnostic CT imaging to reduce noise or radiation dose to the patient. The non-linear nature of these algorithms leads to non-linearities in the imaging chain. However, the methods to assess the performance of CT imaging systems were developed assuming the linear process of filtered backprojection (FBP). Those methods may not be suitable any longer when applied to non-linear systems. In order to evaluate the imaging performance, a phantom is typically scanned and the image quality is measured using various indices. For reasons of practicality, cost, and durability, those phantoms often consist of simple water containers with uniform cylinder inserts. However, these phantoms do not represent the rich structure and patterns of real tissue accurately. As a result, the measured image quality or detectability performance for lesions may not reflect the performance on clinical images. The discrepancy between estimated and real performance may be even larger for iterative methods which sometimes produce "plastic-like", patchy images with homogeneous patterns. Consequently, more realistic phantoms should be used to assess the performance of iterative algorithms. We designed and constructed a biological phantom consisting of porcine organs and tissue that models a human abdomen, including liver lesions. We scanned the phantom on a clinical CT scanner and compared basic image quality indices between filtered backprojection and an iterative reconstruction algorithm.

Evaluation of the effect scan pattern has on the trueness and precision of six intraoral digital impression systems.

PubMed

Mennito, Anthony S; Evans, Zachary P; Lauer, Abigail W; Patel, Ravi B; Ludlow, Mark E; Renne, Walter G

2018-03-01

Clinicians have been slow to adopt digital impression technologies due possibly to perceived technique sensitivities involved in data acquisition. This research has two aims: determine whether scan pattern and sequence affects the accuracy of the three-dimensional (3D) model created from this digital impression and to compare the 5 imaging systems with regards to their scanning accuracy for sextant impressions. Six digital intraoral impression systems were used to scan a typodont sextant with optical properties similar to natural teeth. The impressions were taken using five different scan patterns and the resulting digital models were overlayed on a master digital model to determine the accuracy of each scanner performing each scan pattern. Furthermore, regardless of scan pattern, each digital impression system was evaluated for accuracy to the other systems in this same manner. No differences of significance were noted in the accuracy of 3D models created using six distinct scan patterns with one exception involving the CEREC Omnicam. Planmeca Planscan was determined to be the truest scanner while 3Shape Trios was determined to be the most precise for sextant impression making. Scan pattern does not significantly affect the accuracy of the resulting digital model for sextant scanning. Companies who make digital impression systems often recommend a scan pattern specific for their system. However, every clinical scanning scenario is different and may require a different approach. Knowing how important scan pattern is with regards to accuracy would be helpful for guiding a growing number of practitioners who are utilizing this technology. © 2018 Wiley Periodicals, Inc.

Clinical 3T MR imaging: mastering the challenges.

PubMed

Tanenbaum, Lawrence N

2006-02-01

3T MRI is ready to meet the needs of clinical practice. SAR limitations are minimized by technical advances and surface coils are available for all core applications. With appropriate adjustments to scanning protocols, one can master the challenges of scanning at 3T; studies of the brain, spine, chest, abdomen, pelvis, vasculature, and extremities can be consistently higher in quality than are those obtained at 1.5T. The superior studies that are obtainable at 3T have great appeal to clinicians who are sophisticated about MR technology in areas, such as neurology, orthopedics, vascular surgery, and oncology,and encourage a shift in referrals toward practices that invest in higher field technology. The greater sensitivity to magnetic susceptibility offers unique benefits in functional neuroimaging, and available software/hardware packages enhance clinical setting feasibility, which adds a source of new referrals. The greater overall signal of 3T can be manipulated to make scanning more comfortable and with less motion artifact because scan times could be half as long. Spectacular anatomic delineation that is provided by high-definition scanning at true 1024 resolution can improve preoperative assessment and may improve sensitivity to smaller lesions. 3T provides practices with an advantage that is sought increasingly by high field strength purchasers in a competitive market. Only cost considerations stand in the way of the eventual domination of 3T systems in the high field strength market.

Hyperspectral imaging fluorescence excitation scanning for colon cancer detection

PubMed Central

Leavesley, Silas J.; Walters, Mikayla; Lopez, Carmen; Baker, Thomas; Favreau, Peter F.; Rich, Thomas C.; Rider, Paul F.; Boudreaux, Carole W.

2016-01-01

Abstract. Optical spectroscopy and hyperspectral imaging have shown the potential to discriminate between cancerous and noncancerous tissue with high sensitivity and specificity. However, to date, these techniques have not been effectively translated to real-time endoscope platforms. Hyperspectral imaging of the fluorescence excitation spectrum represents new technology that may be well suited for endoscopic implementation. However, the feasibility of detecting differences between normal and cancerous mucosa using fluorescence excitation-scanning hyperspectral imaging has not been evaluated. The goal of this study was to evaluate the initial feasibility of using fluorescence excitation-scanning hyperspectral imaging for measuring changes in fluorescence excitation spectrum concurrent with colonic adenocarcinoma using a small pre-pilot-scale sample size. Ex vivo analysis was performed using resected pairs of colorectal adenocarcinoma and normal mucosa. Adenocarcinoma was confirmed by histologic evaluation of hematoxylin and eosin (H&E) permanent sections. Specimens were imaged using a custom hyperspectral imaging fluorescence excitation-scanning microscope system. Results demonstrated consistent spectral differences between normal and cancerous tissues over the fluorescence excitation range of 390 to 450 nm that could be the basis for wavelength-dependent detection of colorectal cancers. Hence, excitation-scanning hyperspectral imaging may offer an alternative approach for discriminating adenocarcinoma from surrounding normal colonic mucosa, but further studies will be required to evaluate the accuracy of this approach using a larger patient cohort. PMID:27792808

The effects of different restorative materials on the detection of approximal caries in cone-beam computed tomography scans with and without metal artifact reduction mode.

PubMed

Cebe, Fatma; Aktan, Ali Murat; Ozsevik, Abdul Semih; Ciftci, Mehmet Ertugrul; Surmelioglu, Hatice Derya

2017-03-01

The aim of this study was to investigate the influence of artifacts produced by different restorative materials on the detection of approximal caries in cone-beam computed tomography (CBCT) scans with and without the application of an artifact-reduction (AR) option. Ninety-eight noncavitated premolar and molar teeth were placed with approximal contacts consisting of 2 sound or carious teeth and 1 mesial-occlusal-distal restored tooth with resin-modified glass-ionomer cement (RMGIC), amalgam, composite, ceramic-based composite (CBC), or computer-aided design-computer-aided manufacturing (CAD-CAM) zirconia materials in between. The teeth were scanned with a CBCT system with and without the AR option. Images were evaluated by 2 observers. The teeth were histologically evaluated, and sensitivity, specificity, and areas under the receiver operating characteristic (ROC) curve were calculated according to the appropriate threshold. Specificity and sensitivity values for contact surfaces ranged from 0-48.39 and 82.93-98.40, respectively. The AR option affected (P < .05) approximal caries detection of the amalgam, composite, CAD-CAM, and CBC groups in contact surfaces and composite and RMGIC groups in noncontact surfaces. Artifacts produced by different restorative materials could affect approximal caries detection in CBCT scans. Use of the AR option with CBCT scans increases the accuracy of approximal caries detection. Copyright © 2016 Elsevier Inc. All rights reserved.

Pneu-Scan - A novel, lightweight two-axis telemetry tracking system

NASA Astrophysics Data System (ADS)

Sullivan, A.

The development of Pneu-Scan, a conically scanning tracking antenna feed for telemetry applications, is described. Pneu-Scan has the advantage of being pneumatically driven, thereby eliminating the need for a heavy electric drive motor. Air from the dehydrator/pressurizer system is used to drive the Pneu-Scan pedestal at a scan speed which is proportional to the continuously varying pressure. The S-band tracking feed of the Pneu-Scan is less than five inches in diameter and is considerably lighter than single-channel monopulse (SCM) feeds. Aperture blocking of Pneu-Scan is more than two times smaller than conventional SCM designs. The antenna reflector of the Pneu-Scan system is a lightweight 5-foot graphite-epoxy parabolical reflector positioned by an elevator-over-azimuth pedestal. The elevation assembly is surrounded by an inflatable rotodome which rotates with azimuth. The rotating sphere was designed to have a minimum wind-induced torque, thereby minimizing the required drive power. The weight of the entire system is less than 135 pounds. The principle characteristics of the Pneu-Scan system are summarized in a table.

Scanning Seismic Intrusion Detector

NASA Technical Reports Server (NTRS)

Lee, R. D.

1982-01-01

Scanning seismic intrusion detector employs array of automatically or manually scanned sensors to determine approximate location of intruder. Automatic-scanning feature enables one operator to tend system of many sensors. Typical sensors used with new system are moving-coil seismic pickups. Detector finds uses in industrial security systems.

A Comparative Study of Alternative Controls and Displays for by the Severely Physically Handicapped

NASA Technical Reports Server (NTRS)

Williams, D.; Simpson, C.; Barker, M.

1984-01-01

A modification of a row/column scanning system was investigated in order to increase the speed and accuracy with which communication aids can be accessed with one or two switches. A selection algorithm was developed and programmed in BASIC to automatically select individuals with the characteristic difficulty in controlling time dependent control and display systems. Four systems were compared: (1) row/column directed scan (2 switches); (2) row/column auto scan (1 switch); (3) row auto scan (1 switch); and (4) column auto scan (1 switch). For this sample population, there were no significant differences among systems for scan time to select the correct target. The row/column auto scan system resulted in significantly more errors than any of the other three systems. Thus, the most widely prescribed system for severely physically disabled individuals turns out for this group to have a higher error rate and no faster communication rate than three other systems that have been considered inappropriate for this group.

A High Rigidity and Precision Scanning Tunneling Microscope with Decoupled XY and Z Scans.

PubMed

Chen, Xu; Guo, Tengfei; Hou, Yubin; Zhang, Jing; Meng, Wenjie; Lu, Qingyou

2017-01-01

A new scan-head structure for the scanning tunneling microscope (STM) is proposed, featuring high scan precision and rigidity. The core structure consists of a piezoelectric tube scanner of quadrant type (for XY scans) coaxially housed in a piezoelectric tube with single inner and outer electrodes (for Z scan). They are fixed at one end (called common end). A hollow tantalum shaft is coaxially housed in the XY -scan tube and they are mutually fixed at both ends. When the XY scanner scans, its free end will bring the shaft to scan and the tip which is coaxially inserted in the shaft at the common end will scan a smaller area if the tip protrudes short enough from the common end. The decoupled XY and Z scans are desired for less image distortion and the mechanically reduced scan range has the superiority of reducing the impact of the background electronic noise on the scanner and enhancing the tip positioning precision. High quality atomic resolution images are also shown.

Measurement of Impulsive Thrust from a Closed Radio Frequency Cavity in Vacuum

NASA Technical Reports Server (NTRS)

White, Harold; March, Paul; Lawrence, James; Vera, Jerry; Sylvester, Andre; Brady, David; Bailey, Paul

2016-01-01

A vacuum test campaign evaluating the impulsive thrust performance of a tapered RF test article excited in the TM212 mode at 1,937 megahertz (MHz) has been completed. The test campaign consisted of a forward thrust phase and reverse thrust phase at less than 8 x 10(exp -6) Torr vacuum with power scans at 40 watts, 60 watts, and 80 watts. The test campaign included a null thrust test effort to identify any mundane sources of impulsive thrust, however none were identified. Thrust data from forward, reverse, and null suggests that the system is consistently performing with a thrust to power ratio of 1.2 +/- 0.1 mN/kW.

System and method for compressive scanning electron microscopy

DOEpatents

Reed, Bryan W

2015-01-13

A scanning transmission electron microscopy (STEM) system is disclosed. The system may make use of an electron beam scanning system configured to generate a plurality of electron beam scans over substantially an entire sample, with each scan varying in electron-illumination intensity over a course of the scan. A signal acquisition system may be used for obtaining at least one of an image, a diffraction pattern, or a spectrum from the scans, the image, diffraction pattern, or spectrum representing only information from at least one of a select subplurality or linear combination of all pixel locations comprising the image. A dataset may be produced from the information. A subsystem may be used for mathematically analyzing the dataset to predict actual information that would have been produced by each pixel location of the image.

A Dual Modality System for Simultaneous Fluorescence and Positron Emission Tomography Imaging of Small Animals

NASA Astrophysics Data System (ADS)

Liu, Shuangquan; Zhang, Bin; Wang, Xin; Li, Lin; Chen, Yan; Liu, Xin; Liu, Fei; Shan, Baoci; Bai, Jing

2011-02-01

A dual-modality imaging system for simultaneous fluorescence molecular tomography (FMT) and positron emission tomography (PET) of small animals has been developed. The system consists of a noncontact 360°-projection FMT module and a flat panel detector pair based PET module, which are mounted orthogonally for the sake of eliminating cross interference. The FMT images and PET data are simultaneously acquired by employing dynamic sampling mode. Phantom experiments, in which the localization and range of radioactive and fluorescence probes are exactly indicated, have been carried out to verify the feasibility of the system. An experimental tumor-bearing mouse is also scanned using the dual-modality simultaneous imaging system, the preliminary fluorescence tomographic images and PET images demonstrate the in vivo performance of the presented dual-modality system.

Infrared zone-scanning system.

PubMed

Belousov, Aleksandr; Popov, Gennady

2006-03-20

Challenges encountered in designing an infrared viewing optical system that uses a small linear detector array based on a zone-scanning approach are discussed. Scanning is performed by a rotating refractive polygon prism with tilted facets, which, along with high-speed line scanning, makes the scanning gear as simple as possible. A method of calculation of a practical optical system to compensate for aberrations during prism rotation is described.

Three-dimensional facial anthropometry of unilateral cleft lip infants with a structured light scanning system.

PubMed

Li, Guanghui; Wei, Jianhua; Wang, Xi; Wu, Guofeng; Ma, Dandan; Wang, Bo; Liu, Yanpu; Feng, Xinghua

2013-08-01

Cleft lip in the presence or absence of a cleft palate is a major public health problem. However, few studies have been published concerning the soft-tissue morphology of cleft lip infants. Currently, obtaining reliable three-dimensional (3D) surface models of infants remains a challenge. The aim of this study was to investigate a new way of capturing 3D images of cleft lip infants using a structured light scanning system. In addition, the accuracy and precision of the acquired facial 3D data were validated and compared with direct measurements. Ten unilateral cleft lip patients were enrolled in the study. Briefly, 3D facial images of the patients were acquired using a 3D scanner device before and after the surgery. Fourteen items were measured by direct anthropometry and 3D image software. The accuracy and precision of the 3D system were assessed by comparative analysis. The anthropometric data obtained using the 3D method were in agreement with the direct anthropometry measurements. All data calculated by the software were 'highly reliable' or 'reliable', as defined in the literature. The localisation of four landmarks was not consistent in repeated experiments of inter-observer reliability in preoperative images (P<0.05), while the intra-observer reliability in both pre- and postoperative images was good (P>0.05). The structured light scanning system is proven to be a non-invasive, accurate and precise method in cleft lip anthropometry. Copyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Quantitative approach for optimizing e-beam condition of photoresist inspection and measurement

NASA Astrophysics Data System (ADS)

Lin, Chia-Jen; Teng, Chia-Hao; Cheng, Po-Chung; Sato, Yoshishige; Huang, Shang-Chieh; Chen, Chu-En; Maruyama, Kotaro; Yamazaki, Yuichiro

2018-03-01

Severe process margin in advanced technology node of semiconductor device is controlled by e-beam metrology system and e-beam inspection system with scanning electron microscopy (SEM) image. By using SEM, larger area image with higher image quality is required to collect massive amount of data for metrology and to detect defect in a large area for inspection. Although photoresist is the one of the critical process in semiconductor device manufacturing, observing photoresist pattern by SEM image is crucial and troublesome especially in the case of large image. The charging effect by e-beam irradiation on photoresist pattern causes deterioration of image quality, and it affect CD variation on metrology system and causes difficulties to continue defect inspection in a long time for a large area. In this study, we established a quantitative approach for optimizing e-beam condition with "Die to Database" algorithm of NGR3500 on photoresist pattern to minimize charging effect. And we enhanced the performance of measurement and inspection on photoresist pattern by using optimized e-beam condition. NGR3500 is the geometry verification system based on "Die to Database" algorithm which compares SEM image with design data [1]. By comparing SEM image and design data, key performance indicator (KPI) of SEM image such as "Sharpness", "S/N", "Gray level variation in FOV", "Image shift" can be retrieved. These KPIs were analyzed with different e-beam conditions which consist of "Landing Energy", "Probe Current", "Scanning Speed" and "Scanning Method", and the best e-beam condition could be achieved with maximum image quality, maximum scanning speed and minimum image shift. On this quantitative approach of optimizing e-beam condition, we could observe dependency of SEM condition on photoresist charging. By using optimized e-beam condition, measurement could be continued on photoresist pattern over 24 hours stably. KPIs of SEM image proved image quality during measurement and inspection was stabled enough.

Development and Implementation of the Waste Management Information System to Support Hanford's River Corridor Cleanup

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nolan, L. M.

2006-07-01

This paper describes the development of a Waste Information Management System (WMIS) to support the waste designation, transportation, and disposal processes used by Washington Closure Hanford, LLC to support cleanup of the Columbia River Corridor. This waste, primarily consisting of remediated burial sites and building demolition debris, is disposed at the Environmental Restoration Disposal Facility (ERDF), which is located in the center of the Hanford Site (an approximately 1460 square kilometers site). WMIS uses a combination of bar-code scanning, hand-held computers, and strategic employment of a radio frequency identification (RFID) tag system to track each waste shipment from waste generationmore » to disposal. (authors)« less

Dynamics and control simulation of the Spacelab Experiment Pointing Mount

NASA Technical Reports Server (NTRS)

Marsh, E. L.; Ward, R. S.

1977-01-01

Computer simulations were developed to evaluate the performance of four Experiment Pointing Mounts (EPM) being considered for Spacelab experiments in the 1980-1990 time frame. The system modeled compromises a multibody system consisting of the shuttle, a mechanical isolation device, the EPM, celestial and inertial sensors, bearings, gimbal torque motors and associated nonlinearities, the experiment payload, and control and estimator algorithms. Each mount was subjected to a common disturbance (shuttle vernier thruster firing and man push off) and command (stellar pointing or solar raster scan) input. The fundamental limitation common to all mounts was found to be sensor noise. System dynamics and hardware nonlinearities have secondary effects on pointing performance for sufficiently high bandwidth.

Method of estimation of scanning system quality

NASA Astrophysics Data System (ADS)

Larkin, Eugene; Kotov, Vladislav; Kotova, Natalya; Privalov, Alexander

2018-04-01

Estimation of scanner parameters is an important part in developing electronic document management system. This paper suggests considering the scanner as a system that contains two main channels: a photoelectric conversion channel and a channel for measuring spatial coordinates of objects. Although both of channels consist of the same elements, the testing of their parameters should be executed separately. The special structure of the two-dimensional reference signal is offered for this purpose. In this structure, the fields for testing various parameters of the scanner are sp atially separated. Characteristics of the scanner are associated with the loss of information when a document is digitized. The methods to test grayscale transmitting ability, resolution and aberrations level are offered.

[Organization of olfactory system of the Indian major carp Labeo rohita (Ham.): a study using scanning and transmission microscopy].

PubMed

Bhute, Y V; Baile, V V

2007-01-01

Catla catla, Labeo rohita, and Cirrhinus mrigala are important alimentary fish in India. Their reproduction (breeding) depends on season. The fish perceive external factors-stimuli and chemical signals through the olfactory system that plays the key role in the central regulation of reproduction. However, in the available literature, any electron microscopy data on organization of olfactory elements in these fish are absent. We have studied ultrastructure of the olfactory organ in male L. rohita by using scanning (SEM) and transmission electron microscopy (TEM). The olfactory organ consists of olfactory epithelium, a short nerve, and olfactory bulb. The organ has oval shape and consists of approximately 47-52 lamellae in adult fish and of 14-20 lamellae in fish at the stage of fingerling. These lamellae originate from the midline raphe. By using SEM, the presence of microvillar sensory and ciliated non-sensory cells in these lamellae is shown. By using TEM, a microvillar receptor cell is revealed, which has rough endoplasmic reticulum and Golgi apparatus towards the apical end. Basal cells are found at the base of the receptor cell; supporting cells are located adjacent to olfactory receptor neurons, while epithelial cells--in the non-sensory part of olfactory epithelium. Mast, blastema and macrophages cells are also found in the basal lamina. This work is the first publication on structural organization of olfactory system of the Indian major carp, which provides information about morphological and ultrastructural organization of olfactory system and opens new opportunities for study of chemical neuroanatomy, sensory signal processing, and nervous regulation of reproduction of the Indian major carp.

Virtual Instrument Simulator for CERES

NASA Technical Reports Server (NTRS)

Chapman, John J.

1997-01-01

A benchtop virtual instrument simulator for CERES (Clouds and the Earth's Radiant Energy System) has been built at NASA, Langley Research Center in Hampton, VA. The CERES instruments will fly on several earth orbiting platforms notably NASDA's Tropical Rainfall Measurement Mission (TRMM) and NASA's Earth Observing System (EOS) satellites. CERES measures top of the atmosphere radiative fluxes using microprocessor controlled scanning radiometers. The CERES Virtual Instrument Simulator consists of electronic circuitry identical to the flight unit's twin microprocessors and telemetry interface to the supporting spacecraft electronics and two personal computers (PC) connected to the I/O ports that control azimuth and elevation gimbals. Software consists of the unmodified TRW developed Flight Code and Ground Support Software which serves as the instrument monitor and NASA/TRW developed engineering models of the scanners. The CERES Instrument Simulator will serve as a testbed for testing of custom instrument commands intended to solve in-flight anomalies of the instruments which could arise during the CERES mission. One of the supporting computers supports the telemetry display which monitors the simulator microprocessors during the development and testing of custom instrument commands. The CERES engineering development software models have been modified to provide a virtual instrument running on a second supporting computer linked in real time to the instrument flight microprocessor control ports. The CERES Instrument Simulator will be used to verify memory uploads by the CERES Flight Operations TEAM at NASA. Plots of the virtual scanner models match the actual instrument scan plots. A high speed logic analyzer has been used to track the performance of the flight microprocessor. The concept of using an identical but non-flight qualified microprocessor and electronics ensemble linked to a virtual instrument with identical system software affords a relatively inexpensive simulation system capable of high fidelity.

Research on Coordinate Transformation Method of Gb-Sar Image Supported by 3d Laser Scanning Technology

NASA Astrophysics Data System (ADS)

Wang, P.; Xing, C.

2018-04-01

In the image plane of GB-SAR, identification of deformation distribution is usually carried out by artificial interpretation. This method requires analysts to have adequate experience of radar imaging and target recognition, otherwise it can easily cause false recognition of deformation target or region. Therefore, it is very meaningful to connect two-dimensional (2D) plane coordinate system with the common three-dimensional (3D) terrain coordinate system. To improve the global accuracy and reliability of the transformation from 2D coordinates of GB-SAR images to local 3D coordinates, and overcome the limitation of traditional similarity transformation parameter estimation method, 3D laser scanning data is used to assist the transformation of GB-SAR image coordinates. A straight line fitting method for calculating horizontal angle was proposed in this paper. After projection into a consistent imaging plane, we can calculate horizontal rotation angle by using the linear characteristics of the structure in radar image and the 3D coordinate system. Aided by external elevation information by 3D laser scanning technology, we completed the matching of point clouds and pixels on the projection plane according to the geometric projection principle of GB-SAR imaging realizing the transformation calculation of GB-SAR image coordinates to local 3D coordinates. Finally, the effectiveness of the method is verified by the GB-SAR deformation monitoring experiment on the high slope of Geheyan dam.

Micro-optical design of a three-dimensional microlens scanner for vertically integrated micro-opto-electro-mechanical systems.

PubMed

Baranski, Maciej; Bargiel, Sylwester; Passilly, Nicolas; Gorecki, Christophe; Jia, Chenping; Frömel, Jörg; Wiemer, Maik

2015-08-01

This paper presents the optical design of a miniature 3D scanning system, which is fully compatible with the vertical integration technology of micro-opto-electro-mechanical systems (MOEMS). The constraints related to this integration strategy are considered, resulting in a simple three-element micro-optical setup based on an afocal scanning microlens doublet and a focusing microlens, which is tolerant to axial position inaccuracy. The 3D scanning is achieved by axial and lateral displacement of microlenses of the scanning doublet, realized by micro-electro-mechanical systems microactuators (the transmission scanning approach). Optical scanning performance of the system is determined analytically by use of the extended ray transfer matrix method, leading to two different optical configurations, relying either on a ball lens or plano-convex microlenses. The presented system is aimed to be a core component of miniature MOEMS-based optical devices, which require a 3D optical scanning function, e.g., miniature imaging systems (confocal or optical coherence microscopes) or optical tweezers.

In situ real-time imaging of self-sorted supramolecular nanofibres

NASA Astrophysics Data System (ADS)

Onogi, Shoji; Shigemitsu, Hajime; Yoshii, Tatsuyuki; Tanida, Tatsuya; Ikeda, Masato; Kubota, Ryou; Hamachi, Itaru

2016-08-01

Self-sorted supramolecular nanofibres—a multicomponent system that consists of several types of fibre, each composed of distinct building units—play a crucial role in complex, well-organized systems with sophisticated functions, such as living cells. Designing and controlling self-sorting events in synthetic materials and understanding their structures and dynamics in detail are important elements in developing functional artificial systems. Here, we describe the in situ real-time imaging of self-sorted supramolecular nanofibre hydrogels consisting of a peptide gelator and an amphiphilic phosphate. The use of appropriate fluorescent probes enabled the visualization of self-sorted fibres entangled in two and three dimensions through confocal laser scanning microscopy and super-resolution imaging, with 80 nm resolution. In situ time-lapse imaging showed that the two types of fibre have different formation rates and that their respective physicochemical properties remain intact in the gel. Moreover, we directly visualized stochastic non-synchronous fibre formation and observed a cooperative mechanism.

Optimization of GATE and PHITS Monte Carlo code parameters for spot scanning proton beam based on simulation with FLUKA general-purpose code

NASA Astrophysics Data System (ADS)

Kurosu, Keita; Das, Indra J.; Moskvin, Vadim P.

2016-01-01

Spot scanning, owing to its superior dose-shaping capability, provides unsurpassed dose conformity, in particular for complex targets. However, the robustness of the delivered dose distribution and prescription has to be verified. Monte Carlo (MC) simulation has the potential to generate significant advantages for high-precise particle therapy, especially for medium containing inhomogeneities. However, the inherent choice of computational parameters in MC simulation codes of GATE, PHITS and FLUKA that is observed for uniform scanning proton beam needs to be evaluated. This means that the relationship between the effect of input parameters and the calculation results should be carefully scrutinized. The objective of this study was, therefore, to determine the optimal parameters for the spot scanning proton beam for both GATE and PHITS codes by using data from FLUKA simulation as a reference. The proton beam scanning system of the Indiana University Health Proton Therapy Center was modeled in FLUKA, and the geometry was subsequently and identically transferred to GATE and PHITS. Although the beam transport is managed by spot scanning system, the spot location is always set at the center of a water phantom of 600 × 600 × 300 mm3, which is placed after the treatment nozzle. The percentage depth dose (PDD) is computed along the central axis using 0.5 × 0.5 × 0.5 mm3 voxels in the water phantom. The PDDs and the proton ranges obtained with several computational parameters are then compared to those of FLUKA, and optimal parameters are determined from the accuracy of the proton range, suppressed dose deviation, and computational time minimization. Our results indicate that the optimized parameters are different from those for uniform scanning, suggesting that the gold standard for setting computational parameters for any proton therapy application cannot be determined consistently since the impact of setting parameters depends on the proton irradiation technique. We therefore conclude that customization parameters must be set with reference to the optimized parameters of the corresponding irradiation technique in order to render them useful for achieving artifact-free MC simulation for use in computational experiments and clinical treatments.

Radiological Monitoring Equipment For Real-Time Quantification Of Area Contamination In Soils And Facility Decommissioning

DOE Office of Scientific and Technical Information (OSTI.GOV)

M. V. Carpenter; Jay A. Roach; John R Giles

2005-09-01

The environmental restoration industry offers several sys¬tems that perform scan-type characterization of radiologically contaminated areas. The Idaho National Laboratory (INL) has developed and deployed a suite of field systems that rapidly scan, characterize, and analyse radiological contamination in surface soils. The base system consists of a detector, such as sodium iodide (NaI) spectrometers, a global positioning system (GPS), and an integrated user-friendly computer interface. This mobile concept was initially developed to provide precertifica¬tion analyses of soils contaminated with uranium, thorium, and radium at the Fernald Closure Project, near Cincinnati, Ohio. INL has expanded the functionality of this basic system tomore » create a suite of integrated field-deployable analytical systems. Using its engineering and radiation measurement expertise, aided by computer hardware and software support, INL has streamlined the data acquisition and analysis process to provide real-time information presented on wireless screens and in the form of coverage maps immediately available to field technicians. In addition, custom software offers a user-friendly interface with user-selectable alarm levels and automated data quality monitoring functions that validate the data. This system is deployed from various platforms, depending on the nature of the survey. The deployment platforms include a small all-terrain vehicle used to survey large, relatively flat areas, a hand-pushed unit for areas where manoeuvrability is important, an excavator-mounted system used to scan pits and trenches where personnel access is restricted, and backpack- mounted systems to survey rocky shoreline features and other physical settings that preclude vehicle-based deployment. Variants of the base system include sealed proportional counters for measuring actinides (i.e., plutonium-238 and americium-241) in building demolitions, soil areas, roadbeds, and process line routes at the Miamisburg Closure Project near Dayton, Ohio. In addition, INL supports decontamination operations at the Oak Ridge National Laboratory.« less

Development and evaluation of a digital dental modeling method based on grating projection and reverse engineering software.

PubMed

Zhou, Qin; Wang, Zhenzhen; Chen, Jun; Song, Jun; Chen, Lu; Lu, Yi

2016-01-01

For reasons of convenience and economy, attempts have been made to transform traditional dental gypsum casts into 3-dimensional (3D) digital casts. Different scanning devices have been developed to generate digital casts; however, each has its own limitations and disadvantages. The purpose of this study was to develop an advanced method for the 3D reproduction of dental casts by using a high-speed grating projection system and noncontact reverse engineering (RE) software and to evaluate the accuracy of the method. The methods consisted of 3 main steps: the scanning and acquisition of 3D dental cast data with a high-resolution grating projection system, the reconstruction and measurement of digital casts with RE software, and the evaluation of the accuracy of this method using 20 dental gypsum casts. The common anatomic landmarks were measured directly on the gypsum casts with a Vernier caliper and on the 3D digital casts with the Geomagic software measurement tool. Data were statistically assessed with the t test. The grating projection system had a rapid scanning speed, and smooth 3D dental casts were obtained. The mean differences between the gypsum and 3D measurements were approximately 0.05 mm, and no statistically significant differences were found between the 2 methods (P>.05), except for the measurements of the incisor tooth width and maxillary arch length. A method for the 3D reconstruction of dental casts was developed by using a grating projection system and RE software. The accuracy of the casts generated using the grating projection system was comparable with that of the gypsum casts. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

A Computer-Controlled Laser Bore Scanner

NASA Astrophysics Data System (ADS)

Cheng, Charles C.

1980-08-01

This paper describes the design and engineering of a laser scanning system for production applications. The laser scanning techniques, the timing control, the logic design of the pattern recognition subsystem, the digital computer servo control for the loading and un-loading of parts, and the laser probe rotation and its synchronization will be discussed. The laser inspection machine is designed to automatically inspect the surface of precision-bored holes, such as those in automobile master cylinders, without contacting the machined surface. Although the controls are relatively sophisticated, operation of the laser inspection machine is simple. A laser light beam from a commercially available gas laser, directed through a probe, scans the entire surface of the bore. Reflected light, picked up through optics by photoelectric sensors, generates signals that are fed to a mini-computer for processing. A pattern recognition techniques program in the computer determines acceptance or rejection of the part being inspected. The system's acceptance specifications are adjustable and are set to the user's established tolerances. However, the computer-controlled laser system is capable of defining from 10 to 75 rms surface finish, and voids or flaws from 0.0005 to 0.020 inch. Following the successful demonstration with an engineering prototype, the described laser machine has proved its capability to consistently ensure high-quality master brake cylinders. It thus provides a safety improvement for the automotive braking system. Flawless, smooth cylinder bores eliminate premature wearing of the rubber seals, resulting in a longer-lasting master brake cylinder and a safer and more reliable automobile. The results obtained from use of this system, which has been in operation about a year for replacement of a tedious, manual operation on one of the high-volume lines at the Bendix Hydraulics Division, have been very satisfactory.

Ultrashort pulsed laser (USPL) application in dentistry: basic investigations of ablation rates and thresholds on oral hard tissue and restorative materials.

PubMed

Schelle, Florian; Polz, Sebastian; Haloui, Hatim; Braun, Andreas; Dehn, Claudia; Frentzen, Matthias; Meister, Jörg

2014-11-01

Modern ultrashort pulse lasers with scanning systems provide a huge set of parameters affecting the suitability for dental applications. The present study investigates thresholds and ablation rates of oral hard tissues and restorative materials with a view towards a clinical application system. The functional system consists of a 10 W Nd:YVO4 laser emitting pulses with a duration of 8 ps at 1,064 nm. Measurements were performed on dentin, enamel, ceramic, composite, and mammoth ivory at a repetition rate of 500 kHz. By employing a scanning system, square-shaped cavities with an edge length of 1 mm were created. Ablation threshold and rate measurements were assessed by variation of the applied fluence. Examinations were carried out employing a scanning electron microscope and optical profilometer. Irradiation time was recorded by the scanner software in order to calculate the overall ablated volume per time. First high power ablation rate measurements were performed employing a laser source with up to 50 W. Threshold values in the range of 0.45 J/cm(2) (composite) to 1.54 J/cm(2) (enamel) were observed. Differences between any two materials are statistically significant (p < 0.05). Preparation speeds up to 37.53 mm(3)/min (composite) were achieved with the 10 W laser source and differed statistically significant for any two materials (p < 0.05) with the exception of dentin and mammoth ivory (p > 0.05). By employing the 50 W laser source, increased rates up to ∼50 mm(3)/min for dentin were obtained. The results indicate that modern USPL systems provide sufficient ablation rates to be seen as a promising technology for dental applications.

Quantitative determination of enzyme activity in single cells by scanning microelectrode coupled with a nitrocellulose film-covered microreactor by means of a scanning electrochemical microscope.

PubMed

Zhang, Xiaoli; Sun, Fuchan; Peng, Xuewei; Jin, Wenrui

2007-02-01

An electrochemical method for quantitative determination of enzyme activity in single cells was developed by scanning a microelectrode (ME) over a nitrocellulose film-covered microreactor with micropores by means of a scanning electrochemical microscope (SECM). Peroxidase (PO) in neutrophils was chosen as the model system. The microreactor consisted of a microwell with a solution and a nitrocellulose film with micropores. A single cell perforated by digitonin was injected into the microwell. After the perforated cell was lysed and allowed to dry, physiological buffer saline (PBS) containing hydroquinone (H2Q) and H2O2 as substrates of the enzyme-catalyzed reaction was added in the microwell. The microwell containing the extract of the lysed cell and the enzyme substrates was covered with Parafilm to prevent evaporation. The solution in the microwell was incubated for 20 min. In this case, the released PO from the cell converted H2Q into benzoquinone (BQ). Then, the Parafilm was replaced by a nitrocellulose film with micropores to fabricate the microreactor. The microreactor was placed in an electrochemical cell containing PBS, H2Q, and H2O2. After a 10-microm-radius Au ME was inserted into the electrochemical cell and approached down to the microreactor, the ME was scanned along the central line across the microreactor by means of a SECM. The scan curve with a peak was obtained by detecting BQ that diffused out from the microreactor through the micropores on the nitrocellulose film. PO activity could be quantified on the basis of the peak current on the scan curve using a calibration curve. This method had two obvious advantages: no electrode fouling and no oxygen interference.

Comparative Geometrical Accuracy Investigations of Hand-Held 3d Scanning Systems - AN Update

NASA Astrophysics Data System (ADS)

Kersten, T. P.; Lindstaedt, M.; Starosta, D.

2018-05-01

Hand-held 3D scanning systems are increasingly available on the market from several system manufacturers. These systems are deployed for 3D recording of objects with different size in diverse applications, such as industrial reverse engineering, and documentation of museum exhibits etc. Typical measurement distances range from 0.5 m to 4.5 m. Although they are often easy-to-use, the geometric performance of these systems, especially the precision and accuracy, are not well known to many users. First geometrical investigations of a variety of diverse hand-held 3D scanning systems were already carried out by the Photogrammetry & Laser Scanning Lab of the HafenCity University Hamburg (HCU Hamburg) in cooperation with two other universities in 2016. To obtain more information about the accuracy behaviour of the latest generation of hand-held 3D scanning systems, HCU Hamburg conducted further comparative geometrical investigations using structured light systems with speckle pattern (Artec Spider, Mantis Vision PocketScan 3D, Mantis Vision F5-SR, Mantis Vision F5-B, and Mantis Vision F6), and photogrammetric systems (Creaform HandySCAN 700 and Shining FreeScan X7). In the framework of these comparative investigations geometrically stable reference bodies were used. The appropriate reference data was acquired by measurements with two structured light projection systems (AICON smartSCAN and GOM ATOS I 2M). The comprehensive test results of the different test scenarios are presented and critically discussed in this contribution.

Two-dimensional thermography image retrieval from zig-zag scanned data with TZ-SCAN

NASA Astrophysics Data System (ADS)

Okumura, Hiroshi; Yamasaki, Ryohei; Arai, Kohei

2008-10-01

TZ-SCAN is a simple and low cost thermal imaging device which consists of a single point radiation thermometer on a tripod with a pan-tilt rotator, a DC motor controller board with a USB interface, and a laptop computer for rotator control, data acquisition, and data processing. TZ-SCAN acquires a series of zig-zag scanned data and stores the data as CSV file. A 2-D thermal distribution image can be retrieved by using the second quefrency peak calculated from TZ-SCAN data. An experiment is conducted to confirm the validity of the thermal retrieval algorithm. The experimental result shows efficient accuracy for 2-D thermal distribution image retrieval.

Application of adaptive antenna techniques to future commercial satellite communication

NASA Technical Reports Server (NTRS)

Ersoy, L.; Lee, E. A.; Matthews, E. W.

1987-01-01

The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

Application of adaptive antenna techniques to future commercial satellite communications. Executive summary

NASA Technical Reports Server (NTRS)

Ersoy, L.; Lee, E. A.; Matthews, E. W.

1987-01-01

The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further subdivided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

Discrete pre-processing step effects in registration-based pipelines, a preliminary volumetric study on T1-weighted images

PubMed Central

2017-01-01

Pre-processing MRI scans prior to performing volumetric analyses is common practice in MRI studies. As pre-processing steps adjust the voxel intensities, the space in which the scan exists, and the amount of data in the scan, it is possible that the steps have an effect on the volumetric output. To date, studies have compared between and not within pipelines, and so the impact of each step is unknown. This study aims to quantify the effects of pre-processing steps on volumetric measures in T1-weighted scans within a single pipeline. It was our hypothesis that pre-processing steps would significantly impact ROI volume estimations. One hundred fifteen participants from the OASIS dataset were used, where each participant contributed three scans. All scans were then pre-processed using a step-wise pipeline. Bilateral hippocampus, putamen, and middle temporal gyrus volume estimations were assessed following each successive step, and all data were processed by the same pipeline 5 times. Repeated-measures analyses tested for a main effects of pipeline step, scan-rescan (for MRI scanner consistency) and repeated pipeline runs (for algorithmic consistency). A main effect of pipeline step was detected, and interestingly an interaction between pipeline step and ROI exists. No effect for either scan-rescan or repeated pipeline run was detected. We then supply a correction for noise in the data resulting from pre-processing. PMID:29023597

DSN Beowulf Cluster-Based VLBI Correlator

NASA Technical Reports Server (NTRS)

Rogstad, Stephen P.; Jongeling, Andre P.; Finley, Susan G.; White, Leslie A.; Lanyi, Gabor E.; Clark, John E.; Goodhart, Charles E.

2009-01-01

The NASA Deep Space Network (DSN) requires a broadband VLBI (very long baseline interferometry) correlator to process data routinely taken as part of the VLBI source Catalogue Maintenance and Enhancement task (CAT M&E) and the Time and Earth Motion Precision Observations task (TEMPO). The data provided by these measurements are a crucial ingredient in the formation of precision deep-space navigation models. In addition, a VLBI correlator is needed to provide support for other VLBI related activities for both internal and external customers. The JPL VLBI Correlator (JVC) was designed, developed, and delivered to the DSN as a successor to the legacy Block II Correlator. The JVC is a full-capability VLBI correlator that uses software processes running on multiple computers to cross-correlate two-antenna broadband noise data. Components of this new system (see Figure 1) consist of Linux PCs integrated into a Beowulf Cluster, an existing Mark5 data storage system, a RAID array, an existing software correlator package (SoftC) originally developed for Delta DOR Navigation processing, and various custom- developed software processes and scripts. Parallel processing on the JVC is achieved by assigning slave nodes of the Beowulf cluster to process separate scans in parallel until all scans have been processed. Due to the single stream sequential playback of the Mark5 data, some ramp-up time is required before all nodes can have access to required scan data. Core functions of each processing step are accomplished using optimized C programs. The coordination and execution of these programs across the cluster is accomplished using Pearl scripts, PostgreSQL commands, and a handful of miscellaneous system utilities. Mark5 data modules are loaded on Mark5 Data systems playback units, one per station. Data processing is started when the operator scans the Mark5 systems and runs a script that reads various configuration files and then creates an experiment-dependent status database used to delegate parallel tasks between nodes and storage areas (see Figure 2). This script forks into three processes: extract, translate, and correlate. Each of these processes iterates on available scan data and updates the status database as the work for each scan is completed. The extract process coordinates and monitors the transfer of data from each of the Mark5s to the Beowulf RAID storage systems. The translate process monitors and executes the data conversion processes on available scan files, and writes the translated files to the slave nodes. The correlate process monitors the execution of SoftC correlation processes on the slave nodes for scans that have completed translation. A comparison of the JVC and the legacy Block II correlator outputs reveals they are well within a formal error, and that the data are comparable with respect to their use in flight navigation. The processing speed of the JVC is improved over the Block II correlator by a factor of 4, largely due to the elimination of the reel-to-reel tape drives used in the Block II correlator.

A new generation scanning system for the high-speed analysis of nuclear emulsions

NASA Astrophysics Data System (ADS)

Alexandrov, A.; Buonaura, A.; Consiglio, L.; D'Ambrosio, N.; De Lellis, G.; Di Crescenzo, A.; Galati, G.; Lauria, A.; Montesi, M. C.; Tioukov, V.; Vladymyrov, M.

2016-06-01

The development of automatic scanning systems was a fundamental issue for large scale neutrino detectors exploiting nuclear emulsions as particle trackers. Such systems speed up significantly the event analysis in emulsion, allowing the feasibility of experiments with unprecedented statistics. In the early 1990s, R&D programs were carried out by Japanese and European laboratories leading to automatic scanning systems more and more efficient. The recent progress in the technology of digital signal processing and of image acquisition allows the fulfillment of new systems with higher performances. In this paper we report the description and the performance of a new generation scanning system able to operate at the record speed of 84 cm2/hour and based on the Large Angle Scanning System for OPERA (LASSO) software infrastructure developed by the Naples scanning group. Such improvement, reduces the scanning time by a factor 4 with respect to the available systems, allowing the readout of huge amount of nuclear emulsions in reasonable time. This opens new perspectives for the employment of such detectors in a wider variety of applications.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szoka de Valladares, M.R.; Mack, S.

The DOE Hydrogen Program needs to develop criteria as part of a systematic evaluation process for proposal identification, evaluation and selection. The H Scan component of this process provides a framework in which a project proposer can fully describe their candidate technology system and its components. The H Scan complements traditional methods of capturing cost and technical information. It consists of a special set of survey forms designed to elicit information so expert reviewers can assess the proposal relative to DOE specified selection criteria. The Analytic Hierarchy Process (AHP) component of the decision process assembles the management defined evaluation andmore » selection criteria into a coherent multi-level decision construct by which projects can be evaluated in pair-wise comparisons. The AHP model will reflect management`s objectives and it will assist in the ranking of individual projects based on the extent to which each contributes to management`s objectives. This paper contains a detailed description of the products and activities associated with the planning and evaluation process: The objectives or criteria; the H Scan; and The Analytic Hierarchy Process (AHP).« less

[Comparative Study on Evaluating the Bladder Volume between BladderScan BVI9400 and Ultrasound System iU22].

PubMed

Luo, Huanli; Wang, Ying; Li, Fang; Ling, Yun; Yang, Dingyi; Jin, Fu

2015-07-01

To evaluate the accuracy of the latest BladderScan BVI9400 on measuring bladder volume. Two bladder phantoms were selected for investigating the accuracy of BVI9400. 341 patients with the iU22 ultrasound examinations were followed by BVI 9400. The difference and correlation between BVI9400 and iU22 were contrastively analyzed. The relative difference between results from BVI9400 and phantom volume was 2.5% and 1.36%. There was a strong correlation for patients between BVI9400 and iU22 (R = 0.96, P < 0.001). The relative difference between BVI9400 and iU22 decreased with the increasing of bladder volume and had no significant difference with patient's gender (P > 0.1). BladderScan BVI9400 had the ability of high accuracy and good stability of measured data. In view of quick and conveniences, BVI9400 could be as auxiliary equipment on pelvic tumor to evaluate whether the bladder volume during fractional radiotherapy was consistency with that during CT positioning.

Radiography versus computed tomography for displacement assessment in calcaneal fractures.

PubMed

Ogawa, Brent K; Charlton, Timothy P; Thordarson, David B

2009-10-01

Coronal computed tomography (CT) scans are commonly used in fracture classification systems for calcaneus fractures. However, they may not accurately reflect the amount of fracture displacement. The purpose of this paper was to determine whether lateral radiographs provide superior assessment of the displacement of the posterior facet compared to coronal CT scans. Lateral radiographs of calcaneus fractures were compared with CT coronal images of the posterior facet in 30 displaced intra-articular calcaneus fractures. The average patient age was 39 years old. Using a Picture Archiving and Communication System (PACS), measurements were obtained to quantify the amount of displacement on the lateral radiograph and compared with the amount of depression on corresponding coronal CT scans. On lateral radiographs, the angle of the depressed portion of the posterior facet relative to the undersurface of the calcaneus averaged 28.2 degrees; Bohler's angle averaged 12.7 degrees. These numbers were poorly correlated (r = 0.25). In corresponding CT images from posterior to anterior, the difference in the amount of displacement of the lateral portion of the displaced articular facet versus the nondisplaced medial, constant fragment, was minimal and consistently underestimated the amount of displacement. Underestimation of the amount of depression and rotation of the posterior facet fragment was seen on the coronal CT scan. We attribute this finding to the combined rotation and depression of the posterior facet which may not be measured accurately with the typical semicoronal CT orientation. While sagittal reconstructed images would show this depression better, if they are unavailable we recommend using lateral radiographs to better gauge the amount of fracture displacement.

Wide-Field Megahertz OCT Imaging of Patients with Diabetic Retinopathy

PubMed Central

Reznicek, Lukas; Kolb, Jan P.; Klein, Thomas; Mohler, Kathrin J.; Huber, Robert; Kernt, Marcus; Märtz, Josef; Neubauer, Aljoscha S.

2015-01-01

Purpose. To evaluate the feasibility of wide-field Megahertz (MHz) OCT imaging in patients with diabetic retinopathy. Methods. A consecutive series of 15 eyes of 15 patients with diagnosed diabetic retinopathy were included. All patients underwent Megahertz OCT imaging, a close clinical examination, slit lamp biomicroscopy, and funduscopic evaluation. To acquire densely sampled, wide-field volumetric datasets, an ophthalmic 1050 nm OCT prototype system based on a Fourier-domain mode-locked (FDML) laser source with 1.68 MHz A-scan rate was employed. Results. We were able to obtain OCT volume scans from all included 15 patients. Acquisition time was 1.8 seconds. Obtained volume datasets consisted of 2088 × 1044 A-scans of 60° of view. Thus, reconstructed en face images had a resolution of 34.8 pixels per degree in x-axis and 17.4 pixels per degree. Due to the densely sampled OCT volume dataset, postprocessed customized cross-sectional B-frames through pathologic changes such as an individual microaneurysm or a retinal neovascularization could be imaged. Conclusions. Wide-field Megahertz OCT is feasible to successfully image patients with diabetic retinopathy at high scanning rates and a wide angle of view, providing information in all three axes. The Megahertz OCT is a useful tool to screen diabetic patients for diabetic retinopathy. PMID:26273665

Wide-Field Megahertz OCT Imaging of Patients with Diabetic Retinopathy.

PubMed

Reznicek, Lukas; Kolb, Jan P; Klein, Thomas; Mohler, Kathrin J; Wieser, Wolfgang; Huber, Robert; Kernt, Marcus; Märtz, Josef; Neubauer, Aljoscha S

2015-01-01

To evaluate the feasibility of wide-field Megahertz (MHz) OCT imaging in patients with diabetic retinopathy. A consecutive series of 15 eyes of 15 patients with diagnosed diabetic retinopathy were included. All patients underwent Megahertz OCT imaging, a close clinical examination, slit lamp biomicroscopy, and funduscopic evaluation. To acquire densely sampled, wide-field volumetric datasets, an ophthalmic 1050 nm OCT prototype system based on a Fourier-domain mode-locked (FDML) laser source with 1.68 MHz A-scan rate was employed. RESULTS. We were able to obtain OCT volume scans from all included 15 patients. Acquisition time was 1.8 seconds. Obtained volume datasets consisted of 2088 × 1044 A-scans of 60° of view. Thus, reconstructed en face images had a resolution of 34.8 pixels per degree in x-axis and 17.4 pixels per degree. Due to the densely sampled OCT volume dataset, postprocessed customized cross-sectional B-frames through pathologic changes such as an individual microaneurysm or a retinal neovascularization could be imaged. Wide-field Megahertz OCT is feasible to successfully image patients with diabetic retinopathy at high scanning rates and a wide angle of view, providing information in all three axes. The Megahertz OCT is a useful tool to screen diabetic patients for diabetic retinopathy.

Direct observation of the actin filament by tip-scan atomic force microscopy

PubMed Central

Narita, Akihiro; Usukura, Eiji; Yagi, Akira; Tateyama, Kiyohiko; Akizuki, Shogo; Kikumoto, Mahito; Matsumoto, Tomoharu; Maéda, Yuichiro; Ito, Shuichi; Usukura, Jiro

2016-01-01

Actin filaments, the actin–myosin complex and the actin–tropomyosin complex were observed by a tip-scan atomic force microscope (AFM), which was recently developed by Olympus as the AFM part of a correlative microscope. This newly developed AFM uses cantilevers of similar size as stage-scan AFMs to improve substantially the spatial and temporal resolution. Such an approach has previously never been possible by a tip-scan system, in which a cantilever moves in the x, y and z directions. We evaluated the performance of this developed tip-scan AFM by observing the molecular structure of actin filaments and the actin–tropomyosin complex. In the image of the actin filament, the molecular interval of the actin subunits (∼5.5 nm) was clearly observed as stripes. From the shape of the stripes, the polarity of the actin filament was directly determined and the results were consistent with the polarity determined by myosin binding. In the image of the actin–tropomyosin complex, each tropomyosin molecule (∼2 nm in diameter) on the actin filament was directly observed without averaging images of different molecules. Each tropomyosin molecule on the actin filament has never been directly observed by AFM or electron microscopy. Thus, our developed tip-scan AFM offers significant potential in observing purified proteins and cellular structures at nanometer resolution. Current results represent an important step in the development of a new correlative microscope to observe nm-order structures at an acceptable frame rate (∼10 s/frame) by AFM at the position indicated by the fluorescent dye observed under a light microscope. PMID:27242058

Holographic Airborne Rotating Lidar Instrument Experiment (HARLIE)

NASA Technical Reports Server (NTRS)

Schwemmer, Geary K.

1998-01-01

Scanning holographic lidar receivers are currently in use in two operational lidar systems, PHASERS (Prototype Holographic Atmospheric Scanner for Environmental Remote Sensing) and now HARLIE (Holographic Airborne Rotating Lidar Instrument Experiment). These systems are based on volume phase holograms made in dichromated gelatin (DCG) sandwiched between 2 layers of high quality float glass. They have demonstrated the practical application of this technology to compact scanning lidar systems at 532 and 1064 nm wavelengths, the ability to withstand moderately high laser power and energy loading, sufficient optical quality for most direct detection systems, overall efficiencies rivaling conventional receivers, and the stability to last several years under typical lidar system environments. Their size and weight are approximately half of similar performing scanning systems using reflective optics. The cost of holographic systems will eventually be lower than the reflective optical systems depending on their degree of commercialization. There are a number of applications that require or can greatly benefit from a scanning capability. Several of these are airborne systems, which either use focal plane scanning, as in the Laser Vegetation Imaging System or use primary aperture scanning, as in the Airborne Oceanographic Lidar or the Large Aperture Scanning Airborne Lidar. The latter class requires a large clear aperture opening or window in the aircraft. This type of system can greatly benefit from the use of scanning transmission holograms of the HARLIE type because the clear aperture required is only about 25% larger than the collecting aperture as opposed to 200-300% larger for scan angles of 45 degrees off nadir.

Special raster scanning for reduction of charging effects in scanning electron microscopy.

PubMed

Suzuki, Kazuhiko; Oho, Eisaku

2014-01-01

A special raster scanning (SRS) method for reduction of charging effects is developed for the field of SEM. Both a conventional fast scan (horizontal direction) and an unusual scan (vertical direction) are adopted for acquiring raw data consisting of many sub-images. These data are converted to a proper SEM image using digital image processing techniques. About sharpness of the image and reduction of charging effects, the SRS is compared with the conventional fast scan (with frame-averaging) and the conventional slow scan. Experimental results show the effectiveness of SRS images. By a successful combination of the proposed scanning method and low accelerating voltage (LV)-SEMs, it is expected that higher-quality SEM images can be more easily acquired by the considerable reduction of charging effects, while maintaining the resolution. © 2013 Wiley Periodicals, Inc.

Lidar-based Research and Innovation at DTU Wind Energy - a Review

NASA Astrophysics Data System (ADS)

Mikkelsen, T.

2014-06-01

As wind turbines during the past decade have increased in size so have the challenges met by the atmospheric boundary-layer meteorologists and the wind energy society to measure and characterize the huge-volume wind fields surpassing and driving them. At the DTU Wind Energy test site "Østerild" for huge wind turbines, the hub-height of a recently installed 8 MW Vestas V164 turbine soars 143 meters up above the ground, and its rotor of amazing 164 meters in diameter make the turbine tips flicker 225 meters into the sky. Following the revolution in photonics-based telecommunication at the turn of the Millennium new fibre-based wind lidar technologies emerged and DTU Wind Energy, at that time embedded within Rise National Laboratory, began in collaboration with researchers from wind lidar companies to measure remote sensed wind profiles and turbulence structures within the atmospheric boundary layer with the emerging, at that time new, all-fibre-based 1.55 μ coherent detection wind lidars. Today, ten years later, DTU Wind Energy routinely deploys ground-based vertical profilers instead of met masts for high-precision measurements of mean wind profiles and turbulence profiles. At the departments test site "Høvsøre" DTU Wind Energy also routinely calibrate and accredit wind lidar manufactures wind lidars. Meanwhile however, new methodologies for power curve assessment based on ground-based and nacelle based lidars have also emerged. For improving the turbines power curve assessments and for advancing their control with feed-forward wind measurements experience has also been gained with wind lidars installed on turbine nacelles and integrated into the turbines rotating spinners. A new mobile research infrastructure WindScanner.dk has also emerged at DTU Wind Energy. Wind and turbulence fields are today scanned from sets of three simultaneously in space and time synchronized scanning lidars. One set consists of three fast scanning continuous-wave based wind lidars (short-range system), and another consisting of three synchronized pulsed wind lidar systems (long-range system). Today, wind lidar profilers and WindScanners are routinely deployed and operated during field tests and measurement campaigns. Lidars have been installed and operated from ground, on offshore platforms, and also as scanning lidars integrated in operating turbines. As a result, wind profiles and also detailed 3D scanning of wind and turbulence fields have been achieved: 1) of the free wind aloft, 2) over complex terrain, 3) at coastal ranges with land-sea interfaces, 4) offshore, 5) in turbine inflow induction zone, and 6) of the complex and turbulent flow fields in the wakes inside wind parks.

Measurement and Evaluation of Quantitative Performance of PET/CT Images before a Multicenter Clinical Trial.

PubMed

Zhu, Yanjia; Geng, Caizheng; Huang, Jia; Liu, Juzhen; Wu, Ning; Xin, Jun; Xu, Hao; Yu, Lijuan; Geng, Jianhua

2018-06-13

To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT 690 from GE Healthcare. The scanning parameters were the same with the ones to be used in the planned trial. The 18 F-NaF concentration in the background was 5.3 kBq/ml, while the ones in the spheres of diameter 37 mm, 22 mm, 17 mm and 10 mm were 8:1 as to that of the background and the ones in the spheres of diameter 28 mm and 13 mm were 0 kBq/ml. The consistency of hot sphere recovery coefficient (HRC), cold sphere recovery coefficient (CRC), hot sphere contrast (Q H ) and cold sphere contrast (Q c ) among these 8 PET/CTs was analyzed. The variation of the main quantitative parameters of the eight PET/CT systems was within 10%, which is acceptable for the clinical trial.

SU-F-T-165: Daily QA Analysis for Spot Scanning Beamline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poenisch, F; Gillin, M; Sahoo, N

2016-06-15

Purpose: The dosimetric results of our daily quality assurance over the last 8 years for discrete pencil beam scanning proton therapy will be presented. Methods: To perform the dosimetric checks, a multi-ion chamber detector is used, which consists of an array of 5 single parallel plate ion chambers that are aligned as a cross separated by 10cm each. The Tracker is snapped into a jig, which is placed on the tabletop. Different amounts of Solid Water buildup are added to shift the dose distribution. The dosimetric checks consist of 3 parts: position check, range check and volume dose check. Results:more » The average deviation of all position-check data were 0.2±1.3%. For the range check, the average deviation was 0.1%±1.2%, which also corresponds to a range stability of better than 1 mm over all measurements. The volumetric dose output readings were all within ±1% with the exception of 2 occasions when the cable to the dose monitor was being repaired. Conclusion: Morning QA using the Tracker device gives very stable dosimetric readings but is also sensitive to mechanical and output changes in the proton therapy delivery system.« less

A High Rigidity and Precision Scanning Tunneling Microscope with Decoupled XY and Z Scans

PubMed Central

Chen, Xu; Guo, Tengfei; Hou, Yubin; Zhang, Jing

2017-01-01

A new scan-head structure for the scanning tunneling microscope (STM) is proposed, featuring high scan precision and rigidity. The core structure consists of a piezoelectric tube scanner of quadrant type (for XY scans) coaxially housed in a piezoelectric tube with single inner and outer electrodes (for Z scan). They are fixed at one end (called common end). A hollow tantalum shaft is coaxially housed in the XY-scan tube and they are mutually fixed at both ends. When the XY scanner scans, its free end will bring the shaft to scan and the tip which is coaxially inserted in the shaft at the common end will scan a smaller area if the tip protrudes short enough from the common end. The decoupled XY and Z scans are desired for less image distortion and the mechanically reduced scan range has the superiority of reducing the impact of the background electronic noise on the scanner and enhancing the tip positioning precision. High quality atomic resolution images are also shown. PMID:29270242

Optical design for uniform scanning in MEMS-based 3D imaging lidar.

PubMed

Lee, Xiaobao; Wang, Chunhui

2015-03-20

This paper proposes a method for the optical system design of uniform scanning in a larger scan field of view (FOV) in 3D imaging lidar. The theoretical formulas are derived for the design scheme. By employing the optical design software ZEMAX, a foldaway uniform scanning optical system based on MEMS has been designed, and the scanning uniformity and spot size of the system on the target plane, perpendicular to optical axis, are analyzed and discussed. Results show that the designed system can scan uniformly within the FOV of 40°×40° with small spot size for the target at distance of about 100 m.

Compact antenna for two-dimensional beam scan in the JT-60U electron cyclotron heating/current drive system

NASA Astrophysics Data System (ADS)

Moriyama, S.; Kajiwara, K.; Takahashi, K.; Kasugai, A.; Seki, M.; Ikeda, Y.; Fujii, T.

2005-11-01

A compact antenna system was designed and fabricated to enable millimeter-wave beam scanning in the toroidal and poloidal directions of the JT-60U tokamak for electron cyclotron heating (ECH) and electron cyclotron current drive (ECCD) experiments. The antenna consists of a fast movable flat mirror mounted on the tokamak vacuum vessel and a rotary focusing mirror attached at the end of the waveguide that is supported from outside the vacuum vessel. This separate support concept enables a compact structure inside a shallow port (0.68×0.54×0.2m) that is shared with a subport for an independent diagnostic system. During a plasma shot, the flat mirror is driven by a servomotor with a 3-m-long drive shaft to reduce the influence of the high magnetic field on the motor. The focusing mirror is rotated by a simple mechanism utilizing a push rod and an air cylinder. The antenna has been operated reliably for 3 years after a small improvement to the rotary drive mechanism. It has made significant contributions to ECH and ECCD experiments, especially the current profile control in JT-60U.

PUMA: the first results of a nebular spectrograph for the study of the kinematics of interstellar medium

NASA Astrophysics Data System (ADS)

Langarica, Rosalia; Bernal, Abel; Rosado, Margarita; Cobos Duenas, Francisco J.; Garfias, Fernando; Gutierrez, Leonel; Le Coarer, Etienne; Tejada, Carlos; Tinoco, Silvio J.

1998-07-01

The kinematics of the interstellar medium may be studied by means of a scanning Fabry-Perot interferometer (SFPI). This allows the coverage of a wider field of view with higher spatial and spectral resolution than when a high-dispersion classical spectrograph is used. The system called PUMA consists of a focal reducer and a SFPI installed in the 2.1 m telescope of the San Pedro Martir National Astronomical Observatory (SPM), Mexico, in its f/7.5 configuration. It covers a field of view of 10 arcmin providing direct images as well as interferograms which are focused on a 1024 X 1024 Tektronix CCD, covering a wide spectral range. It is considered the integration of other optical elements for further developments. The optomechanical system and the developed software allow exact, remote positioning of all movable parts and control the FPI scanning and data acquisition. The parallelism of the interferometer plates is automatically achieved by a custom method. The PUMA provides spectral resolutions of 0.414 Angstrom and a free spectral range of 19.8 Angstrom. Results of high quality that compete with those obtained by similar systems in bigger telescopes, are presented.

High-spatial-resolution nanoparticle x-ray fluorescence tomography

NASA Astrophysics Data System (ADS)

Larsson, Jakob C.; Vâgberg, William; Vogt, Carmen; Lundström, Ulf; Larsson, Daniel H.; Hertz, Hans M.

2016-03-01

X-ray fluorescence tomography (XFCT) has potential for high-resolution 3D molecular x-ray bio-imaging. In this technique the fluorescence signal from targeted nanoparticles (NPs) is measured, providing information about the spatial distribution and concentration of the NPs inside the object. However, present laboratory XFCT systems typically have limited spatial resolution (>1 mm) and suffer from long scan times and high radiation dose even at high NP concentrations, mainly due to low efficiency and poor signal-to-noise ratio. We have developed a laboratory XFCT system with high spatial resolution (sub-100 μm), low NP concentration and vastly decreased scan times and dose, opening up the possibilities for in-vivo small-animal imaging research. The system consists of a high-brightness liquid-metal-jet microfocus x-ray source, x-ray focusing optics and an energy-resolving photon-counting detector. By using the source's characteristic 24 keV line-emission together with carefully matched molybdenum nanoparticles the Compton background is greatly reduced, increasing the SNR. Each measurement provides information about the spatial distribution and concentration of the Mo nanoparticles. A filtered back-projection method is used to produce the final XFCT image.

Particle Accelerator Focus Automation

NASA Astrophysics Data System (ADS)

Lopes, José; Rocha, Jorge; Redondo, Luís; Cruz, João

2017-08-01

The Laboratório de Aceleradores e Tecnologias de Radiação (LATR) at the Campus Tecnológico e Nuclear, of Instituto Superior Técnico (IST) has a horizontal electrostatic particle accelerator based on the Van de Graaff machine which is used for research in the area of material characterization. This machine produces alfa (He+) and proton (H+) beams of some μA currents up to 2 MeV/q energies. Beam focusing is obtained using a cylindrical lens of the Einzel type, assembled near the high voltage terminal. This paper describes the developed system that automatically focuses the ion beam, using a personal computer running the LabVIEW software, a multifunction input/output board and signal conditioning circuits. The focusing procedure consists of a scanning method to find the lens bias voltage which maximizes the beam current measured on a beam stopper target, which is used as feedback for the scanning cycle. This system, as part of a wider start up and shut down automation system built for this particle accelerator, brings great advantages to the operation of the accelerator by turning it faster and easier to operate, requiring less human presence, and adding the possibility of total remote control in safe conditions.

Note: long-range scanning tunneling microscope for the study of nanostructures on insulating substrates.

PubMed

Molina-Mendoza, Aday J; Rodrigo, José G; Island, Joshua; Burzuri, Enrique; Rubio-Bollinger, Gabino; van der Zant, Herre S J; Agraït, Nicolás

2014-02-01

The scanning tunneling microscope (STM) is a powerful tool for studying the electronic properties at the atomic level, however, it is of relatively small scanning range and the fact that it can only operate on conducting samples prevents its application to study heterogeneous samples consisting of conducting and insulating regions. Here we present a long-range scanning tunneling microscope capable of detecting conducting micro and nanostructures on insulating substrates using a technique based on the capacitance between the tip and the sample and performing STM studies.

Positron Scanner for Locating Brain Tumors

DOE R&D Accomplishments Database

Rankowitz, S.; Robertson, J. S.; Higinbotham, W. A.; Rosenblum, M. J.

1962-03-01

A system is described that makes use of positron emitting isotopes for locating brain tumors. This system inherently provides more information about the distribution of radioactivity in the head in less time than existing scanners which use one or two detectors. A stationary circular array of 32 scintillation detectors scans a horizontal layer of the head from many directions simultaneously. The data, consisting of the number of counts in all possible coincidence pairs, are coded and stored in the memory of a Two-Dimensional Pulse-Height Analyzer. A unique method of displaying and interpreting the data is described that enables rapid approximate analysis of complex source distribution patterns. (auth)

Prototype development of a Geostationary Synthetic Thinned Aperture Radiometer, GeoSTAR

NASA Technical Reports Server (NTRS)

Tanner, A. B.; Wilson, W. J.; Kangaslahti, P. P.; Lambrigsten, B. H.; Dinardo, S. J.; Piepmeier, J. R.; Ruf, C. S.; Rogacki, S.; Gross, S. M.; Musko, S.

2004-01-01

Preliminary details of a 2-D synthetic aperture radiometer prototype operating from 50 to 55 GHz will be presented. The laboratory prototype is being developed to demonstrate the technologies and system design needed to do millimeter-wave atmospheric soundings with high spatial resolution from Geostationary orbit. The concept is to deploy a large thinned aperture Y-array on a geostationary satellite, and to use aperture synthesis to obtain images of the Earth without the need for a large mechanically scanned antenna. The laboratory prototype consists of a Y-array of 24 horn antennas, MMIC receivers, and a digital cross-correlation sub-system.

Fluoroscopic image-guided intervention system for transbronchial localization

NASA Astrophysics Data System (ADS)

Rai, Lav; Keast, Thomas M.; Wibowo, Henky; Yu, Kun-Chang; Draper, Jeffrey W.; Gibbs, Jason D.

2012-02-01

Reliable transbronchial access of peripheral lung lesions is desirable for the diagnosis and potential treatment of lung cancer. This procedure can be difficult, however, because accessory devices (e.g., needle or forceps) cannot be reliably localized while deployed. We present a fluoroscopic image-guided intervention (IGI) system for tracking such bronchoscopic accessories. Fluoroscopy, an imaging technology currently utilized by many bronchoscopists, has a fundamental shortcoming - many lung lesions are invisible in its images. Our IGI system aligns a digitally reconstructed radiograph (DRR) defined from a pre-operative computed tomography (CT) scan with live fluoroscopic images. Radiopaque accessory devices are readily apparent in fluoroscopic video, while lesions lacking a fluoroscopic signature but identifiable in the CT scan are superimposed in the scene. The IGI system processing steps consist of: (1) calibrating the fluoroscopic imaging system; (2) registering the CT anatomy with its depiction in the fluoroscopic scene; (3) optical tracking to continually update the DRR and target positions as the fluoroscope is moved about the patient. The end result is a continuous correlation of the DRR and projected targets with the anatomy depicted in the live fluoroscopic video feed. Because both targets and bronchoscopic devices are readily apparent in arbitrary fluoroscopic orientations, multiplane guidance is straightforward. The system tracks in real-time with no computational lag. We have measured a mean projected tracking accuracy of 1.0 mm in a phantom and present results from an in vivo animal study.

Performance of the NIRS fast scanning system for heavy-ion radiotherapy.

PubMed

Furukawa, Takuji; Inaniwa, Taku; Sato, Shinji; Shirai, Toshiyuki; Takei, Yuka; Takeshita, Eri; Mizushima, Kota; Iwata, Yoshiyuki; Himukai, Takeshi; Mori, Shinichiro; Fukuda, Shigekazu; Minohara, Shinichi; Takada, Eiichi; Murakami, Takeshi; Noda, Koji

2010-11-01

A project to construct a new treatment facility, as an extension of the existing HIMAC facility, has been initiated for the further development of carbon-ion therapy at NIRS. This new treatment facility is equipped with a 3D irradiation system with pencil-beam scanning. The challenge of this project is to realize treatment of a moving target by scanning irradiation. To achieve fast rescanning within an acceptable irradiation time, the authors developed a fast scanning system. In order to verify the validity of the design and to demonstrate the performance of the fast scanning prior to use in the new treatment facility, a new scanning-irradiation system was developed and installed into the existing HIMAC physics-experiment course. The authors made strong efforts to develop (1) the fast scanning magnet and its power supply, (2) the high-speed control system, and (3) the beam monitoring. The performance of the system including 3D dose conformation was tested by using the carbon beam from the HIMAC accelerator. The performance of the fast scanning system was verified by beam tests. Precision of the scanned beam position was less than +/-0.5 mm. By cooperating with the planning software, the authors verified the homogeneity of the delivered field within +/-3% for the 3D delivery. This system took only 20 s to deliver the physical dose of 1 Gy to a spherical target having a diameter of 60 mm with eight rescans. In this test, the average of the spot-staying time was considerably reduced to 154 micros, while the minimum staying time was 30 micros. As a result of this study, the authors verified that the new scanning delivery system can produce an accurate 3D dose distribution for the target volume in combination with the planning software.

Consistency of metabolic tumor volume of non-small-cell lung cancer primary tumor measured using 18F-FDG PET/CT at two different tracer uptake times.

PubMed

Liu, Haiping; Chen, Ping; Wroblewski, Kristen; Hou, Peng; Zhang, Chen-Peng; Jiang, Yulei; Pu, Yonglin

2016-01-01

The objective of this study was to test the hypothesis that the metabolic tumor volume (MTV) of primary non-small-cell lung cancer is not sensitive to differences in F-fluorodeoxyglucose (F-FDG) uptake time, and to compare this consistency of MTV measurements with that of standardized uptake value (SUV) and total lesion glycolysis (TLG). Under Institutional Review Board approval, 134 consecutive patients with histologically proven non-small-cell lung cancer underwent F-FDG PET/computed tomography scanning at about 1 h (early) and 2 h (delayed) after intravenous injection of F-FDG. MTV, SUV, and TLG of the primary tumor were all measured. Student's t-test and Wilcoxon's signed-rank test for paired data were used to compare MTV, SUV, and TLG between the two scans. The intraclass correlation coefficient (ICC) was used to assess agreement in PET parameters between the two scans and between the measurements made by two observers. MTV was not significantly different (P=0.17) between the two scans. However, SUVmax, SUVmean, SUVpeak, and TLG increased significantly from the early to the delayed scans (P<0.0001 for all). The median percentage change between the two scans in MTV (1.65%) was smaller than in SUVmax (11.76%), SUVmean(10.57%), SUVpeak(13.51%), and TLG (14.34%); the ICC of MTV (0.996) was greater than that of SUVmax (0.933), SUVmean (0.952), SUVpeak (0.928), and TLG (0.982). Interobserver agreement between the two radiologists was excellent for MTV, SUV, and TLG on both scans (ICC: 0.934-0.999). MTV is not sensitive to common clinical variations in F-FDG uptake time, its consistency is greater than that of SUVmax, SUVmean, SUVpeak, and TLG, and it has excellent interobserver agreement.

NIKOS II - A System For Non-Invasive Imaging Of Coronary Arteries With Synchrotron Radiation

NASA Astrophysics Data System (ADS)

Dix, Wolf-Rainer; Engelke, Klaus; Heuer, Joachim; Graeff, Walter; Kupper, Wolfram; Lohmann, Michael; Makin, I.; Moechel, Thomas; Reumann, Reinhold

1989-10-01

Aim of the work is the visualization of coronary arteries down to 1 mm diameter with an iodine mass density of 1 mg/cm , thus allowing non-invasive investigations by intravenous injection of the contrast agent. Digital Subtraction Angiography (DSA) in energy subtraction mode (dichromography) is employed for this purpose. The two images Cor subtraction are taken at photon energies just below and above the iodine K-edge (33.17 keV). After subtraction the background contrast - such as bone and soft tissue - is suppressed and the iodinated structures are strongly enhanced because of the abrupt change of absorption at the edge. The two monoenergetic beams (bandwidth about 250 eV) with high intensity (about 1011 photons/mm /s) are only available if synchrotron radiation is used. In HASYLAB at DESY (Hamburg, FRG) the system NIKOS was developed for dichromography. It consists of six main parts: A wiggler beam line, a monochromator which filters the two 12 cm wide beams out of the white synchrotron radiation beam, a fast scanning device, a fast low-noise two-line detector, a safety system and a computer system. At present, one scan (two images) lasts 1 s. The images from the in-vivo investigations of dogs have been promising. The right coronary artery (diameter 1.5 mm) was clearly visible.

Prediction-error in the context of real social relationships modulates reward system activity.

PubMed

Poore, Joshua C; Pfeifer, Jennifer H; Berkman, Elliot T; Inagaki, Tristen K; Welborn, Benjamin L; Lieberman, Matthew D

2012-01-01

The human reward system is sensitive to both social (e.g., validation) and non-social rewards (e.g., money) and is likely integral for relationship development and reputation building. However, data is sparse on the question of whether implicit social reward processing meaningfully contributes to explicit social representations such as trust and attachment security in pre-existing relationships. This event-related fMRI experiment examined reward system prediction-error activity in response to a potent social reward-social validation-and this activity's relation to both attachment security and trust in the context of real romantic relationships. During the experiment, participants' expectations for their romantic partners' positive regard of them were confirmed (validated) or violated, in either positive or negative directions. Primary analyses were conducted using predefined regions of interest, the locations of which were taken from previously published research. Results indicate that activity for mid-brain and striatal reward system regions of interest was modulated by social reward expectation violation in ways consistent with prior research on reward prediction-error. Additionally, activity in the striatum during viewing of disconfirmatory information was associated with both increases in post-scan reports of attachment anxiety and decreases in post-scan trust, a finding that follows directly from representational models of attachment and trust.

Paediatric patient navigation models of care in Canada: An environmental scan.

PubMed

Luke, Alison; Doucet, Shelley; Azar, Rima

2018-05-01

(1) To provide other organizations with useful information when implementing paediatric navigation programs and (2) to inform the implementation of a navigation care centre in New Brunswick for children with complex health conditions. This environmental scan consisted of a literature review of published and grey literature for paediatric patient navigation programs across Canada. Additional programs were found following discussions with program coordinators and navigators. Interviews were conducted with key staff from each program and included questions related to patient condition; target population and location; method delivery; navigator background; and navigator roles. Data analysis included analysis of interviews and identification of common themes across the different programs. We interviewed staff from 19 paediatric navigation programs across Canada. Programs varied across a number of different themes, including: condition and disease type, program location (e.g., hospital or clinic), navigator background (e.g., registered nurse or peer/lay navigator) and method of delivery (e.g., phone or face-to-face). Overall, navigator roles are similar across all programs, including advocacy, education, support and assistance in accessing resources from both within and outside the health care system. This scan offers a road map of Canadian paediatric navigation programs. Knowledge learned from this scan will inform stakeholders who are either involved in the delivery of paediatric patient navigation programs or planning to implement such a program. Specifically, our scan informed the development of a navigation centre for children with complex health conditions in New Brunswick.

Capillary array scanner for time-resolved detection and identification of fluorescently labelled DNA fragments.

PubMed

Neumann, M; Herten, D P; Dietrich, A; Wolfrum, J; Sauer, M

2000-02-25

The first capillary array scanner for time-resolved fluorescence detection in parallel capillary electrophoresis based on semiconductor technology is described. The system consists essentially of a confocal fluorescence microscope and a x,y-microscope scanning stage. Fluorescence of the labelled probe molecules was excited using a short-pulse diode laser emitting at 640 nm with a repetition rate of 50 MHz. Using a single filter system the fluorescence decays of different labels were detected by an avalanche photodiode in combination with a PC plug-in card for time-correlated single-photon counting (TCSPC). The time-resolved fluorescence signals were analyzed and identified by a maximum likelihood estimator (MLE). The x,y-microscope scanning stage allows for discontinuous, bidirectional scanning of up to 16 capillaries in an array, resulting in longer fluorescence collection times per capillary compared to scanners working in a continuous mode. Synchronization of the alignment and measurement process were developed to allow for data acquisition without overhead. Detection limits in the subzeptomol range for different dye molecules separated in parallel capillaries have been achieved. In addition, we report on parallel time-resolved detection and separation of more than 400 bases of single base extension DNA fragments in capillary array electrophoresis. Using only semiconductor technology the presented technique represents a low-cost alternative for high throughput DNA sequencing in parallel capillaries.

MO-DE-210-06: Development of a Supercompounded 3D Volumetric Ultrasound Image Guidance System for Prone Accelerated Partial Breast Irradiation (APBI)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chiu, T; Hrycushko, B; Zhao, B

2015-06-15

Purpose: For early-stage breast cancer, accelerated partial breast irradiation (APBI) is a cost-effective breast-conserving treatment. Irradiation in a prone position can mitigate respiratory induced breast movement and achieve maximal sparing of heart and lung tissues. However, accurate dose delivery is challenging due to breast deformation and lumpectomy cavity shrinkage. We propose a 3D volumetric ultrasound (US) image guidance system for accurate prone APBI Methods: The designed system, set beneath the prone breast board, consists of a water container, an US scanner, and a two-layer breast immobilization cup. The outer layer of the breast cup forms the inner wall of watermore » container while the inner layer is attached to patient breast directly to immobilization. The US transducer scans is attached to the outer-layer of breast cup at the dent of water container. Rotational US scans in a transverse plane are achieved by simultaneously rotating water container and transducer, and multiple transverse scanning forms a 3D scan. A supercompounding-technique-based volumetric US reconstruction algorithm is developed for 3D image reconstruction. The performance of the designed system is evaluated with two custom-made gelatin phantoms containing several cylindrical inserts filled in with water (11% reflection coefficient between materials). One phantom is designed for positioning evaluation while the other is for scaling assessment. Results: In the positioning evaluation phantom, the central distances between the inserts are 15, 20, 30 and 40 mm. The distances on reconstructed images differ by −0.19, −0.65, −0.11 and −1.67 mm, respectively. In the scaling evaluation phantom, inserts are 12.7, 19.05, 25.40 and 31.75 mm in diameter. Measured inserts’ sizes on images differed by 0.23, 0.19, −0.1 and 0.22 mm, respectively. Conclusion: The phantom evaluation results show that the developed 3D volumetric US system can accurately localize target position and determine target volume, and is a promising image-guidance tool for prone APBI.« less

Online Magnetic Resonance Image Guided Adaptive Radiation Therapy: First Clinical Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Acharya, Sahaja; Fischer-Valuck, Benjamin W.; Kashani, Rojano

Purpose: To demonstrate the feasibility of online adaptive magnetic resonance (MR) image guided radiation therapy (MR-IGRT) through reporting of our initial clinical experience and workflow considerations. Methods and Materials: The first clinically deployed online adaptive MR-IGRT system consisted of a split 0.35T MR scanner straddling a ring gantry with 3 multileaf collimator-equipped {sup 60}Co heads. The unit is supported by a Monte Carlo–based treatment planning system that allows real-time adaptive planning with the patient on the table. All patients undergo computed tomography and MR imaging (MRI) simulation for initial treatment planning. A volumetric MRI scan is acquired for each patient atmore » the daily treatment setup. Deformable registration is performed using the planning computed tomography data set, which allows for the transfer of the initial contours and the electron density map to the daily MRI scan. The deformed electron density map is then used to recalculate the original plan on the daily MRI scan for physician evaluation. Recontouring and plan reoptimization are performed when required, and patient-specific quality assurance (QA) is performed using an independent in-house software system. Results: The first online adaptive MR-IGRT treatments consisted of 5 patients with abdominopelvic malignancies. The clinical setting included neoadjuvant colorectal (n=3), unresectable gastric (n=1), and unresectable pheochromocytoma (n=1). Recontouring and reoptimization were deemed necessary for 3 of 5 patients, and the initial plan was deemed sufficient for 2 of the 5 patients. The reasons for plan adaptation included tumor progression or regression and a change in small bowel anatomy. In a subsequently expanded cohort of 170 fractions (20 patients), 52 fractions (30.6%) were reoptimized online, and 92 fractions (54.1%) were treated with an online-adapted or previously adapted plan. The median time for recontouring, reoptimization, and QA was 26 minutes. Conclusion: Online adaptive MR-IGRT has been successfully implemented with planning and QA workflow suitable for routine clinical application. Clinical trials are in development to formally evaluate adaptive treatments for a variety of disease sites.« less

Bone scanning in severe external otitis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levin, W.J.; Shary, J.H. 3d.; Nichols, L.T.

1986-11-01

Technetium99 Methylene Diphosphate bone scanning has been considered an early valuable tool to diagnose necrotizing progressive malignant external otitis. However, to our knowledge, no formal studies have actually compared bone scans of otherwise young, healthy patients with severe external otitis to scans of patients with clinical presentation of malignant external otitis. Twelve patients with only severe external otitis were studied with Technetium99 Diphosphate and were compared to known cases of malignant otitis. All scans were evaluated by two neuroradiologists with no prior knowledge of the clinical status of the patients. Nine of the 12 patients had positive bone scans withmore » many scans resembling those reported with malignant external otitis. Interestingly, there was no consistent correlation between the severity of clinical presentation and the amount of Technetium uptake. These findings suggest that a positive bone scan alone should not be interpreted as indicative of malignant external otitis.« less

Clinical utility of MRI and SPECT in the diagnosis of cognitive impairment referred to memory clinic.

PubMed

Guinane, John; Ng, Boon Lung

2018-05-01

ABSTRACTBackground:Despite of their limited availability and potential for significant variation between and within each modality, this is the first study to prospectively measure the clinical utility of MRI and/or SPECT brain scanning in addition to the routine diagnostic workup of patients presenting to memory clinic. A single center study was conducted over a convenience of 12-month sampling period. For each patient referred for MRI and/or SPECT scanning, the primary geriatrician or psychogeriatrician was asked to assign an initial diagnosis. The initial diagnosis was then compared with the final consensus diagnosis after any scans or neuropsychology testing had been completed. During the 12-month study period, 66 patients (26%) were referred for scans out of a total of 253 patients included in the study. There were 16/44 (36%) positive MRI outcomes and 13/35 (37%) positive SPECT outcomes. The diagnosis changed consistent with the MRI scan findings in 11/44 (25%) and changed consistent with the SPECT scan findings in 9/35 (26%). Potentially reversible pathology was identified in a single patient, 1/50 (2%), via an MRI scan that suggested normal pressure hydrocephalus. The number needed to test for one positive outcome was 3.8 (95% CI 2.0-23.3), 6.0 (95% CI NA), and 1.7 (95% CI 1.3-2.5) for MRI only, SPECT only, and MRI and SPECT together, respectively. The clinical utility of MRI and/or SPECT scanning in this study may be broadly superior to the available international evidence, and further research is needed to identify predictors of positive scan outcomes.

Computer Vision Tool and Technician as First Reader of Lung Cancer Screening CT Scans.

PubMed

Ritchie, Alexander J; Sanghera, Calvin; Jacobs, Colin; Zhang, Wei; Mayo, John; Schmidt, Heidi; Gingras, Michel; Pasian, Sergio; Stewart, Lori; Tsai, Scott; Manos, Daria; Seely, Jean M; Burrowes, Paul; Bhatia, Rick; Atkar-Khattra, Sukhinder; van Ginneken, Bram; Tammemagi, Martin; Tsao, Ming Sound; Lam, Stephen

2016-05-01

To implement a cost-effective low-dose computed tomography (LDCT) lung cancer screening program at the population level, accurate and efficient interpretation of a large volume of LDCT scans is needed. The objective of this study was to evaluate a workflow strategy to identify abnormal LDCT scans in which a technician assisted by computer vision (CV) software acts as a first reader with the aim to improve speed, consistency, and quality of scan interpretation. Without knowledge of the diagnosis, a technician reviewed 828 randomly batched scans (136 with lung cancers, 556 with benign nodules, and 136 without nodules) from the baseline Pan-Canadian Early Detection of Lung Cancer Study that had been annotated by the CV software CIRRUS Lung Screening (Diagnostic Image Analysis Group, Nijmegen, The Netherlands). The scans were classified as either normal (no nodules ≥1 mm or benign nodules) or abnormal (nodules or other abnormality). The results were compared with the diagnostic interpretation by Pan-Canadian Early Detection of Lung Cancer Study radiologists. The overall sensitivity and specificity of the technician in identifying an abnormal scan were 97.8% (95% confidence interval: 96.4-98.8) and 98.0% (95% confidence interval: 89.5-99.7), respectively. Of the 112 prevalent nodules that were found to be malignant in follow-up, 92.9% were correctly identified by the technician plus CV compared with 84.8% by the study radiologists. The average time taken by the technician to review a scan after CV processing was 208 ± 120 seconds. Prescreening CV software and a technician as first reader is a promising strategy for improving the consistency and quality of screening interpretation of LDCT scans. Copyright © 2016 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

A scanning Raman lidar for observing the spatio-temporal distribution of water vapor

NASA Astrophysics Data System (ADS)

Yabuki, Masanori; Matsuda, Makoto; Nakamura, Takuji; Hayashi, Taiichi; Tsuda, Toshitaka

2016-12-01

We have constructed a scanning Raman lidar to observe the cross-sectional distribution of the water vapor mixing ratio and aerosols near the Earth's surface, which are difficult to observe when a conventional Raman lidar system is used. The Raman lidar is designed for a nighttime operating system by employing a ultra-violet (UV) laser source and can measure the water vapor mixing ratio at an altitude up to 7 km using vertically pointing observations. The scanning mirror system consists of reflective flat mirrors and a rotational stage. By using a program-controlled rotational stage, a vertical scan can be operated with a speed of 1.5°/s. The beam was pointed at 33 angles over range of 0-48° for the elevation angle with a constant step width of 1.5°. The range-height cross sections of the water vapor and aerosol within a 400 m range can be obtained for 25 min. The lidar signals at each direction were individually smoothed with the moving average to spread proportionally with the distance from the laser-emitting point. The averaged range at a distance of 200 m (400 m) from the lidar was 30.0 m (67.5 m) along the lidar signal in a specific direction. The experimental observations using the scanning lidar were conducted at night in the Shigaraki MU radar observatory located on a plateau with undulating topography and surrounded by forests. The root mean square error (RMSE) between the temporal variations of the water vapor mixing ratio by the scanning Raman lidar and by an in-situ weather sensor equipped with a tethered balloon was 0.17 g/kg at an altitude of 100 m. In cross-sectional measurements taken at altitudes and horizontal distances up to 400 m from the observatory, we found that the water vapor mixing ratio above and within the surface layer varied vertically and horizontally. The spatio-temporal variability of water vapor near the surface seemed to be sensitive to topographic variations as well as the wind field and the temperature gradient over the site. From the wide-range cross-sectional observations of the water vapor mixing ratio and the backscatter ratio of aerosols within a 2000 m range, we can detect small-scale water vapor structures on a horizontal scale of several hundred meters in the atmospheric boundary layer.

Comparative microstructures and cytotoxicity assays for ballistic aerosols composed of micrometals and nanometals: respiratory health implications

PubMed Central

Machado, Brenda I; Suro, Raquel M; Garza, Kristine M; Murr, Lawrence E

2011-01-01

Aerosol particulates collected on filters from ballistic penetration and erosion events for W–Ni–Co and W–Ni–Fe kinetic energy rod projectiles penetrating steel target plates were observed to be highly cytotoxic to human epithelial A549 lung cells in culture after 48 hours of exposure. The aerosol consisted of micron-sized Fe particulates and nanoparticulate aggregates consisting of W, Ni or W, Co, and some Fe, characterized by scanning electron microscopy and transmission electron microscopy, and using energy-dispersive (X-ray) spectrometry for elemental analysis and mapping. Cytotoxic assays of manufactured micron-sized and nanosized metal particulates of W, Ni, Fe, and Co demonstrated that, consistent with many studies in the literature, only the nanoparticulate elements demonstrated measurable cytotoxicity. These results suggest the potential for very severe, short-term, human toxicity, in particular to the respiratory system on inhaling ballistic aerosols. PMID:21499416

Quantitative thin-layer chromatography/mass spectrometry analysis of caffeine using a surface sampling probe electrospray ionization tandem mass spectrometry system.

PubMed

Ford, Michael J; Deibel, Michael A; Tomkins, Bruce A; Van Berkel, Gary J

2005-07-15

Quantitative determination of caffeine on reversed-phase C8 thin-layer chromatography plates using a surface sampling electrospray ionization system with tandem mass spectrometry detection is reported. The thin-layer chromatography/electrospray tandem mass spectrometry method employed a deuterium-labeled caffeine internal standard and selected reaction monitoring detection. Up to nine parallel caffeine bands on a single plate were sampled in a single surface scanning experiment requiring 35 min at a surface scan rate of 44 mum/s. A reversed-phase HPLC/UV caffeine assay was developed in parallel to assess the mass spectrometry method performance. Limits of detection for the HPLC/UV and thin-layer chromatography/electrospray tandem mass spectrometry methods determined from the calibration curve statistics were 0.20 ng injected (0.50 muL) and 1.0 ng spotted on the plate, respectively. Spike recoveries with standards and real samples ranged between 97 and 106% for both methods. The caffeine content of three diet soft drinks (Diet Coke, Diet Cherry Coke, Diet Pepsi) and three diet sport drinks (Diet Turbo Tea, Speed Stack Grape, Speed Stack Fruit Punch) was measured. The HPLC/UV and mass spectrometry determinations were in general agreement, and these values were consistent with the quoted values for two of the three diet colas. In the case of Diet Cherry Coke and the diet sports drinks, the determined caffeine amounts using both methods were consistently higher (by approximately 8% or more) than the literature values.

Quantitative Caffeine Analysis Using a Surface Sampling Probe Electrospray Ionization Tandem Mass Spectrometry System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ford, Michael J; Deibel, Michael A.; Tomkins, Bruce A

Quantitative determination of caffeine on reversed-phase C8 thin-layer chromatography plates using a surface sampling electrospray ionization system with tandem mass spectrometry detection is reported. The thin-layer chromatography/electrospray tandem mass spectrometry method employed a deuterium-labeled caffeine internal standard and selected reaction monitoring detection. Up to nine parallel caffeine bands on a single plate were sampled in a single surface scanning experiment requiring 35 min at a surface scan rate of 44 {mu}m/s. A reversed-phase HPLC/UV caffeine assay was developed in parallel to assess the mass spectrometry method performance. Limits of detection for the HPLC/UV and thin-layer chromatography/electrospray tandem mass spectrometry methodsmore » determined from the calibration curve statistics were 0.20 ng injected (0.50 {mu}L) and 1.0 ng spotted on the plate, respectively. Spike recoveries with standards and real samples ranged between 97 and 106% for both methods. The caffeine content of three diet soft drinks (Diet Coke, Diet Cherry Coke, Diet Pepsi) and three diet sport drinks (Diet Turbo Tea, Speed Stack Grape, Speed Stack Fruit Punch) was measured. The HPLC/UV and mass spectrometry determinations were in general agreement, and these values were consistent with the quoted values for two of the three diet colas. In the case of Diet Cherry Coke and the diet sports drinks, the determined caffeine amounts using both methods were consistently higher (by 8% or more) than the literature values.« less

[Creation and Evaluation of Educational Programs for Additional Delayed Scan of FDG-PET/CT].

PubMed

Wada, Ryota; Kamiya, Takashi; Fujino, Kouichi; Ueda, Junpei; Isohashi, Kayako; Tatsumi, Mitsuaki; Hatazawa, Jun

Generally, FDG-PET/CT image is acquired at the 60th minute after tracer administration. Depending on the clinical case, additional delayed scans may be useful. However, it is difficult to judge whether additional delayed scan is useful or not. The purposes of this study were creation and evaluation of educational programs to help radiological technologists to decide the usefulness of additional delayed scan of FDG-PET/CT. Educational programs consisted of the instructional materials and the judgment test of clinical cases. The instructional materials provided the valuable findings for differentiation between uptake in the wall of the colon and colon content, distinction between uptake in the lymph node and urinary tract, and evaluation of malignancy. The judgment test of clinical cases consisted of 10 cases selected by a nuclear medicine physician (for 5 of that cases additional delayed scan was decided to be useful). Five experienced technologists and five inexperienced technologists scored the volubility of additional delayed scan pre- and post-training using the instructional materials (the full marks of score is 5). After the educational programs using the instructional materials, the score was improved with the significant difference in both experienced (pre: 3.6±1.4, post: 4.0±1.2) and inexperienced (pre: 2.8±1.5, post: 3.7±1.5) groups (p<0.05). According to the educational programs, technologist might be able to decide whether the additional delayed scan is useful or not. The successful results of this study may improve the interpretation or reduce the total exposure dose of the PET/CT scan.

Development of a fast framing detector for electron microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Ian J.; Bustillo, Karen C.; Ciston, Jim

2016-10-01

A high frame rate detector system is described that enables fast real-time data analysis of scanning diffraction experiments in scanning transmission electron microscopy (STEM). This is an end-to-end development that encompasses the data producing detector, data transportation, and real-time processing of data. The detector will consist of a central pixel sensor that is surrounded by annular silicon diodes. Both components of the detector system will synchronously capture data at almost 100 kHz frame rate, which produces an approximately 400 Gb/s data stream. Low-level preprocessing will be implemented in firmware before the data is streamed from the National Center for Electronmore » Microscopy (NCEM) to the National Energy Research Scientific Computing Center (NERSC). Live data processing, before it lands on disk, will happen on the Cori supercomputer and aims to present scientists with prompt experimental feedback. This online analysis will provide rough information of the sample that can be utilized for sample alignment, sample monitoring and verification that the experiment is set up correctly. Only a compressed version of the relevant data is then selected for more in-depth processing.« less

A USPL functional system with articulated mirror arm for in-vivo applications in dentistry

NASA Astrophysics Data System (ADS)

Schelle, Florian; Meister, Jörg; Dehn, Claudia; Oehme, Bernd; Bourauel, Christoph; Frentzen, Mathias

Ultra-short pulsed laser (USPL) systems for dental application have overcome many of their initial disadvantages. However, a problem that has not yet been addressed and solved is the beam delivery into the oral cavity. The functional system that is introduced in this study includes an articulated mirror arm, a scanning system as well as a handpiece, allowing for freehand preparations with ultra-short laser pulses. As laser source an Nd:YVO4 laser is employed, emitting pulses with a duration of tp < 10 ps at a repetition rate of up to 500 kHz. The centre wavelength is at 1064 nm and the average output power can be tuned up to 9 W. The delivery system consists of an articulated mirror arm, to which a scanning system and a custom made handpiece are connected, including a 75 mm focussing lens. The whole functional system is compact in size and moveable. General characteristics like optical losses and ablation rate are determined and compared to results employing a fixed setup on an optical table. Furthermore classical treatment procedures like cavity preparation are being demonstrated on mammoth ivory. This study indicates that freehand preparation employing an USPL system is possible but challenging, and accompanied by a variety of side-effects. The ablation rate with fixed handpiece is about 10 mm3/min. Factors like defocussing and blinding affect treatment efficiency. Laser sources with higher average output powers might be needed in order to reach sufficient preparation speeds.

Transient aortitis documented by positron emission tomography in a case series of men and transgender women infected with syphilis.

PubMed

Joseph Davey, Dvora; Kojima, Noah; Konda, Kelika A; Gupta, Pawan; Leon, Segundo R; Calvo, Gino M; Caceres, Carlos F; Klausner, Jeffrey D

2017-12-01

Syphilis infection persists globally contributing to preventable and treatable morbidity and mortality. How extensive early syphilis disseminates is unknown. To better understand the relationship between early syphilis infection and inflammation over time, our study enrolled six individuals recently infected with syphilis for sequential positron emission tomography (PET) scans. We evaluated a case series of six individuals with high syphilis titres (two secondary, two early latent and two latent, unknown duration, but with high titre) who received sequential PET scans to assess inflammation over time and its response to treatment. At time of PET scan, four of the six individuals were co-infected with HIV. One of the four was not on antiretroviral therapy and three of the four were not virally suppressed (viral load of >400 copies/mL). Baseline rapid plasma reagin (RPR) titres ranged from 1:64 to 1:256 (four of the six participants had prior non-reactive RPR results). Five of the six participants had mild to intense hypermetabolic PET scan activity consistent with cervical (n=5), axillary (n=4), inguinal (n=5) and retroperitoneal (n=1) adenopathy. Mild hypermetabolic activity in the thoracic aortic wall, suggesting aortitis, was present among the same five participants and resolved within 30 days for four of the five participants and 60 days for the other participant. However, widespread lymphadenopathy remained present in PET scans up to 3 months following treatment in two participants. We did not find any abnormal PET scan activity of the central nervous system. We found abnormal aortic wall PET scan activity suggesting aortitis to be common in a case series of patients with early syphilis. In research settings, PET scans may be a sensitive tool to monitor inflammation associated with syphilis. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Development of the micro-scanning optical system of yellow laser applied to the ophthalmologic area

NASA Astrophysics Data System (ADS)

Ortega, Tiago A.; Mota, Alessandro D.; Costal, Glauco Z.; Fontes, Yuri C.; Rossi, Giuliano; Yasuoka, Fatima M. M.; Stefani, Mario A.; de Castro N., Jarbas C.

2012-10-01

In this work, the development of a laser scanning system for ophthalmology with micrometric positioning precision is presented. It is a semi-automatic scanning system for retina photocoagulation and laser trabeculoplasty. The equipment is a solid state laser fully integrated to the slit lamp. An optical system is responsible for producing different laser spot sizes on the image plane and a pair of galvanometer mirrors generates the scanning patterns.

First Clinical Investigation of Cone Beam Computed Tomography and Deformable Registration for Adaptive Proton Therapy for Lung Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veiga, Catarina; Janssens, Guillaume; Teng, Ching-Ling

2016-05-01

Purpose: An adaptive proton therapy workflow using cone beam computed tomography (CBCT) is proposed. It consists of an online evaluation of a fast range-corrected dose distribution based on a virtual CT (vCT) scan. This can be followed by more accurate offline dose recalculation on the vCT scan, which can trigger a rescan CT (rCT) for replanning. Methods and Materials: The workflow was tested retrospectively for 20 consecutive lung cancer patients. A diffeomorphic Morphon algorithm was used to generate the lung vCT by deforming the average planning CT onto the CBCT scan. An additional correction step was applied to account formore » anatomic modifications that cannot be modeled by deformation alone. A set of clinical indicators for replanning were generated according to the water equivalent thickness (WET) and dose statistics and compared with those obtained on the rCT scan. The fast dose approximation consisted of warping the initial planned dose onto the vCT scan according to the changes in WET. The potential under- and over-ranges were assessed as a variation in WET at the target's distal surface. Results: The range-corrected dose from the vCT scan reproduced clinical indicators similar to those of the rCT scan. The workflow performed well under different clinical scenarios, including atelectasis, lung reinflation, and different types of tumor response. Between the vCT and rCT scans, we found a difference in the measured 95% percentile of the over-range distribution of 3.4 ± 2.7 mm. The limitations of the technique consisted of inherent uncertainties in deformable registration and the drawbacks of CBCT imaging. The correction step was adequate when gross errors occurred but could not recover subtle anatomic or density changes in tumors with complex topology. Conclusions: A proton therapy workflow based on CBCT provided clinical indicators similar to those using rCT for patients with lung cancer with considerable anatomic changes.« less

An electromagnetic/electrostatic dual cathode system for electron beam instruments

NASA Technical Reports Server (NTRS)

Bradley, J. G.; Conley, J. M.; Wittry, D. B.; Albee, A. L.

1986-01-01

A method of providing cathode redundancy which consists of two fixed cathodes and uses electromagnetic and/or electrostatic fields to direct the electron beam to the electron optical axis is presented, with application to the cathode system of the Scanning Electron Microscope and Particle Analyzer proposed for NASA's Mariner Mark II Comet Rendezvous/Asteroid Flyby projected for the 1990s. The symmetric double deflection system chosen has the optical property that the image of the effective electron source is formed above the magnet assembly near the apparent position of the effective source, and it makes the transverse positions of the electron sources independent of the electron beam energy. Good performance of the system is found, with the sample imaging resolution being the same as for the single-axis cathode.

Realtime photoacoustic microscopy in vivo with a 30-MHz ultrasound array transducer.

PubMed

Zemp, Roger J; Song, Liang; Bitton, Rachel; Shung, K Kirk; Wang, Lihong V

2008-05-26

We present a novel high-frequency photoacoustic microscopy system capable of imaging the microvasculature of living subjects in realtime to depths of a few mm. The system consists of a high-repetition-rate Q-switched pump laser, a tunable dye laser, a 30-MHz linear ultrasound array transducer, a multichannel high-frequency data acquisition system, and a shared-RAM multi-core-processor computer. Data acquisition, beamforming, scan conversion, and display are implemented in realtime at 50 frames per second. Clearly resolvable images of 6-microm-diameter carbon fibers are experimentally demonstrated at 80 microm separation distances. Realtime imaging performance is demonstrated on phantoms and in vivo with absorbing structures identified to depths of 2.5-3 mm. This work represents the first high-frequency realtime photoacoustic imaging system to our knowledge.

Clouds and the Earth's Radiant Energy System (CERES)

NASA Technical Reports Server (NTRS)

Carman, Stephen L.; Cooper, John E.; Miller, James; Harrison, Edwin F.; Barkstrom, Bruce R.

1992-01-01

The CERES (Clouds and the Earth's Radiant Energy System) experiment will play a major role in NASA's multi-platform Earth Observing System (EOS) program to observe and study the global climate. The CERES instruments will provide EOS scientists with a consistent data base of accurately known fields of radiation and of clouds. CERES will investigate the important question of cloud forcing and its influence on the radiative energy flow through the Earth's atmosphere. The CERES instrument is an improved version of the ERBE (Earth Radiation Budget Experiment) broadband scanning radiometer flown by NASA from 1984 through 1989. This paper describes the science of CERES, presents an overview of the instrument preliminary design, and outlines the issues related to spacecraft pointing and attitude control.

Note: A simple multi-channel optical system for modulation spectroscopies.

PubMed

Solís-Macías, J; Sánchez-López, J D; Castro-García, R; Flores-Camacho, J M; Flores-Rangel, G; Ciou, Jian-Jhih; Chen, Kai-Wei; Chen, Chang-Hsiao; Lastras-Martínez, L F; Balderas-Navarro, R E

2017-12-01

Photoreflectance-difference (PR/PRD) and reflectance-difference (RD) spectroscopies employ synchronic detection usually with lock-in amplifiers operating at moderate (200-1000 Hz) and high (50-100 KHz) modulation frequencies, respectively. Here, we report a measurement system for these spectroscopies based on a multichannel CCD spectrometer without a lock-in amplifier. In the proposed scheme, a typical PRD or RD spectrum consists of numerical subtractions between a thousand CCD captures recorded, while a photoelastic modulator is either operating or inhibited. This is advantageous and fits the slow response of CCD detectors to high modulation frequencies. The resulting spectra are processed with Savitzky-Golay filtering and compared well with those measured with conventional scanning systems based on lock-in amplifiers.

SU-E-T-266: Development of Evaluation System of Optimal Synchrotron Controlling Parameter for Spot Scanning Proton Therapy with Multiple Gate Irradiations in One Operation Cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamada, T; Fujii, Y; Hitachi Ltd., Hitachi-shi, Ibaraki

2015-06-15

Purpose: We have developed a gated spot scanning proton beam therapy system with real-time tumor-tracking. This system has the ability of multiple-gated irradiation in a single synchrotron operation cycle controlling the wait-time for consecutive gate signals during a flat-top phase so that the decrease in irradiation efficiency induced by irregular variation of gate signal is reduced. Our previous studies have shown that a 200 ms wait-time is appropriate to increase the average irradiation efficiency, but the optimal wait-time can vary patient by patient and day by day. In this research, we have developed an evaluation system of the optimal wait-timemore » in each irradiation based on the log data of the real-time-image gated proton beam therapy (RGPT) system. Methods: The developed system consists of logger for operation of RGPT system and software for evaluation of optimal wait-time. The logger records timing of gate on/off, timing and the dose of delivered beam spots, beam energy and timing of X-ray irradiation. The evaluation software calculates irradiation time in the case of different wait-time by simulating the multiple-gated irradiation operation using several timing information. Actual data preserved in the log data are used for gate on and off time, spot irradiation time, and time moving to the next spot. Design values are used for the acceleration and deceleration times. We applied this system to a patient treated with the RGPT system. Results: The evaluation system found the optimal wait-time of 390 ms that reduced the irradiation time by about 10 %. The irradiation time with actual wait-time used in treatment was reproduced with accuracy of 0.2 ms. Conclusion: For spot scanning proton therapy system with multiple-gated irradiation in one synchrotron operation cycle, an evaluation system of the optimal wait-time in each irradiation based on log data has been developed. Funding Support: Japan Society for the Promotion of Science (JSPS) through the FIRST Program.« less

Design and analysis of a sub-aperture scanning machine for the transmittance measurements of large-aperture optical system

NASA Astrophysics Data System (ADS)

He, Yingwei; Li, Ping; Feng, Guojin; Cheng, Li; Wang, Yu; Wu, Houping; Liu, Zilong; Zheng, Chundi; Sha, Dingguo

2010-11-01

For measuring large-aperture optical system transmittance, a novel sub-aperture scanning machine with double-rotating arms (SSMDA) was designed to obtain sub-aperture beam spot. Optical system full-aperture transmittance measurements can be achieved by applying sub-aperture beam spot scanning technology. The mathematical model of the SSMDA based on a homogeneous coordinate transformation matrix is established to develop a detailed methodology for analyzing the beam spot scanning errors. The error analysis methodology considers two fundamental sources of scanning errors, namely (1) the length systematic errors and (2) the rotational systematic errors. As the systematic errors of the parameters are given beforehand, computational results of scanning errors are between -0.007~0.028mm while scanning radius is not lager than 400.000mm. The results offer theoretical and data basis to the research on transmission characteristics of large optical system.

An Automated Medical Information Management System (OpScan-MIMS) in a Clinical Setting

PubMed Central

Margolis, S.; Baker, T.G.; Ritchey, M.G.; Alterescu, S.; Friedman, C.

1981-01-01

This paper describes an automated medical information management system within a clinic setting. The system includes an optically scanned data entry system (OpScan), a generalized, interactive retrieval and storage software system(Medical Information Management System, MIMS) and the use of time-sharing. The system has the advantages of minimal hardware purchase and maintenance, rapid data entry and retrieval, user-created programs, no need for user knowledge of computer language or technology and is cost effective. The OpScan-MIMS system has been operational for approximately 16 months in a sexually transmitted disease clinic. The system's application to medical audit, quality assurance, clinic management and clinical training are demonstrated.

Micro CT characterization of a coastal mine tailings deposit, Portmán Bay, SE Spain

NASA Astrophysics Data System (ADS)

Frigola, Jaime; Cerdà-Domènech, Marc; Barriuso, Eduardo; Sanchez-Vidal, Anna; Amblas, David; Canals, Miquel

2017-04-01

Scanning of sediment cores by means of high-resolution non-destructive techniques provides researchers with huge amounts of highly valuable data allowing fast and detailed characterization of the materials. In the last decades several devoted instruments have been developed and applied to the study of sedimentary sequences, mainly multi-sensor core loggers (MSCL) for the physical properties and XRF core scanners for the chemical elemental composition. The geoscientific community started using computed tomography (CT) systems about two decades ago. These were mainly medical systems as dedicated instruments were essentially lacking by that time. The resolution of those medical systems was limited to several hundreds of micrometres voxel size. Micro computed tomography (micro-CT) systems have also spread into geoscientific research, although their limited workspace dimensions prevents their use for large objects, such as long sediment cores. Recently, a new micro-CT system, the MultiTom Core X-ray CT, conceived by University of Barcelona (UB) researchers and developed by X-ray Engineering, became operational. It is able of scanning sediment cores up to 1.5 m long, and allows adjustable resolutions from 300 microns down to 3-4 microns. The system is now installed at UB's CORELAB Laboratory for non-destructive analyses of geological materials. Here we present, as an example, the results of MultiTom scans of a set of sediment cores recovered offshore Portmán Bay, SE Spain, in order to characterize at very high-resolution the metal-enriched deposit generated after 33 years of direct discharge into the sea of mine tailings resulting from the exploitation of Pb and Zn ores. In total 52 short cores and 6 long gravity cores from the mine tailings infilled bay were scanned with the MultiTom system at a mean voxel resolution of 125 microns. The integrated study of micro-CT data allowed differentiating the main tailings units from deposits formed after disposal cessation. Tailings units show higher radio-density values, which correspond to metal enrichments. A lower unit consists of highly laminated interbedded low radio-density and very high radio-density layers, while an upper mine tailings unit is more homogeneous and shows intermediate radio-density values. The limit between the tailings and the post-mining deposits is defined by a sharp surface associated with an abrupt decrease in the radio-densities. Post-mining deposits are also characterized by an increment in bioturbation marks, which are practically absent in the tailings units, and an increase in carbonate particles and organic matter patches. Micro CT scans allow observation of very small structures, which are indicative of the complexity of the sedimentation processes involved in the transport and final deposition of the mine tailings. Integration of micro CT scans together with XRF core scanner and MSCL data allows a better characterization of the metal concentrations and their distribution within the deposit, directly demonstrating the great value of non-destructive techniques for actually high-resolution sedimentological studies.

New Generation VLBI: Intraday UT1 Estimations

NASA Astrophysics Data System (ADS)

Ipatov, Alexander; Ivanov, Dmitriy; Ilin, Gennadiy; Smolentsev, Sergei; Gayazov, Iskander; Mardyshkin, Vyacheslav; Fedotov, Leonid; Stempkovski, Victor; Vytnov, Alexander; Salnikov, Alexander; Surkis, Igor; Mikhailov, Andrey; Marshalov, Dmitriy; Bezrukov, Ilya; Melnikov, Alexey; Ken, Voytsekh; Kurdubov, Sergei

2016-12-01

IAA finished work on the creation of the new generation radio interferometer with two VGOS antennas co-located at Badary and Zelenchukskaya. 48 single baseline one-hour VLBI sessions (up to four sessions per day) were performed from 04 Nov to 18 Nov 2015. Observations were carried out using wideband S/X receivers, three X-band and one S-band 512 MHz channels at one or two circular polarizations. Sessions consisted of about 60 scans with a 22-second minimum scan duration. The stations' broadband acquisition systems generated 1.5-3 TB data per session, which were transferred via Internet to the IAA FX correlator. The accuracy of the group delay in a single channel was 10-20 ps, which allows the use of every single channel's observations for geodetic analysis without synthesis. 156 single channel NGS-cards were obtained in total. The RMS of the differences between UT1-UTC estimates and IERS finals values is 19 μs.

Non-linear optical flow cytometry using a scanned, Bessel beam light-sheet.

PubMed

Collier, Bradley B; Awasthi, Samir; Lieu, Deborah K; Chan, James W

2015-05-29

Modern flow cytometry instruments have become vital tools for high-throughput analysis of single cells. However, as issues with the cellular labeling techniques often used in flow cytometry have become more of a concern, the development of label-free modalities for cellular analysis is increasingly desired. Non-linear optical phenomena (NLO) are of growing interest for label-free analysis because of the ability to measure the intrinsic optical response of biomolecules found in cells. We demonstrate that a light-sheet consisting of a scanned Bessel beam is an optimal excitation geometry for efficiently generating NLO signals in a microfluidic environment. The balance of photon density and cross-sectional area provided by the light-sheet allowed significantly larger two-photon fluorescence intensities to be measured in a model polystyrene microparticle system compared to measurements made using other excitation focal geometries, including a relaxed Gaussian excitation beam often used in conventional flow cytometers.

Chiral Majorana fermion modes regulated by a scanning tunneling microscope tip

NASA Astrophysics Data System (ADS)

Zhou, Yan-Feng; Hou, Zhe; Zhang, Ying-Tao; Sun, Qing-Feng

2018-03-01

The Majorana fermion can be described by a real wave function with only two phases (zero and π ) which provide a controllable degree of freedom. We propose a strategy to regulate the phase of the chiral Majorana state by coupling with a scanning tunneling microscope tip in a system consisting of a quantum anomalous Hall insulator coupled with a superconductor. With the change in the chemical potential, the chiral Majorana state can be tuned alternately between zero and π , in which the perfect normal tunneling and perfect crossed Andreev reflection appear, respectively. The perfect crossed Andreev reflection, by which a Cooper pair can be split into two electrons going into different terminals completely, leads to a pumping current and distinct quantized resistances. These findings may provide a signature of Majorana fermions and pave a feasible avenue to regulate the phase of the Majorana state.

Color standardization in whole slide imaging using a color calibration slide

PubMed Central

Bautista, Pinky A.; Hashimoto, Noriaki; Yagi, Yukako

2014-01-01

Background: Color consistency in histology images is still an issue in digital pathology. Different imaging systems reproduced the colors of a histological slide differently. Materials and Methods: Color correction was implemented using the color information of the nine color patches of a color calibration slide. The inherent spectral colors of these patches along with their scanned colors were used to derive a color correction matrix whose coefficients were used to convert the pixels’ colors to their target colors. Results: There was a significant reduction in the CIELAB color difference, between images of the same H & E histological slide produced by two different whole slide scanners by 3.42 units, P < 0.001 at 95% confidence level. Conclusion: Color variations in histological images brought about by whole slide scanning can be effectively normalized with the use of the color calibration slide. PMID:24672739

Development of the Mayo Investigational Neuromodulation Control System: toward a closed-loop electrochemical feedback system for deep brain stimulation

PubMed Central

Chang, Su-Youne; Kimble, Christopher J.; Kim, Inyong; Paek, Seungleal B.; Kressin, Kenneth R.; Boesche, Joshua B.; Whitlock, Sidney V.; Eaker, Diane R.; Kasasbeh, Aimen; Horne, April E.; Blaha, Charles D.; Bennet, Kevin E.; Lee, Kendall H.

2014-01-01

Object Conventional deep brain stimulation (DBS) devices continue to rely on an open-loop system in which stimulation is independent of functional neural feedback. The authors previously proposed that as the foundation of a DBS “smart” device, a closed-loop system based on neurochemical feedback, may have the potential to improve therapeutic outcomes. Alterations in neurochemical release are thought to be linked to the clinical benefit of DBS, and fast-scan cyclic voltammetry (FSCV) has been shown to be effective for recording these evoked neurochemical changes. However, the combination of FSCV with conventional DBS devices interferes with the recording and identification of the evoked analytes. To integrate neurochemical recording with neurostimulation, the authors developed the Mayo Investigational Neuromodulation Control System (MINCS), a novel, wirelessly controlled stimulation device designed to interface with FSCV performed by their previously described Wireless Instantaneous Neurochemical Concentration Sensing System (WINCS). Methods To test the functionality of these integrated devices, various frequencies of electrical stimulation were applied by MINCS to the medial forebrain bundle of the anesthetized rat, and striatal dopamine release was recorded by WINCS. The parameters for FSCV in the present study consisted of a pyramidal voltage waveform applied to the carbon-fiber microelectrode every 100 msec, ramping between −0.4 V and +1.5 V with respect to an Ag/AgCl reference electrode at a scan rate of either 400 V/sec or 1000 V/sec. The carbon-fiber microelectrode was held at the baseline potential of −0.4 V between scans. Results By using MINCS in conjunction with WINCS coordinated through an optic fiber, the authors interleaved intervals of electrical stimulation with FSCV scans and thus obtained artifact-free wireless FSCV recordings. Electrical stimulation of the medial forebrain bundle in the anesthetized rat by MINCS elicited striatal dopamine release that was time-locked to stimulation and increased progressively with stimulation frequency. Conclusions Here, the authors report a series of proof-of-principle tests in the rat brain demonstrating MINCS to be a reliable and flexible stimulation device that, when used in conjunction with WINCS, performs wirelessly controlled stimulation concurrent with artifact-free neurochemical recording. These findings suggest that the integration of neurochemical recording with neurostimulation may be a useful first step toward the development of a closed-loop DBS system for human application. PMID:24116724

Safe Active Scanning for Energy Delivery Systems Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Helms, J.; Salazar, B.; Scheibel, P.

The Department of Energy’s Cybersecurity for Energy Delivery Systems Program has funded Safe(r) Active Scanning for Energy Delivery Systems, led by Lawrence Livermore National Laboratory, to investigate and analyze the impacts of active scanning in the operational environment of energy delivery systems. In collaboration with Pacific Northwest National Laboratory and Idaho National Laboratory, active scans across three testbeds including 38 devices were performed. This report gives a summary of the initial literature survey performed on the SASEDS project as well as industry partner interview summaries and main findings from Phase 1 of the project. Additionally, the report goes into themore » details of scanning techniques, methodologies for testing, testbed descriptions, and scanning results, with appendices to elaborate on the specific scans that were performed. As a result of testing, a single device out of 38 exhibited problems when actively scanned, and a reboot was required to fix it. This single failure indicates that active scanning is not likely to have a detrimental effect on the safety and resilience of energy delivery systems. We provide a path forward for future research that could enable wide adoption of active scanning and lead utilities to incorporate active scanning as part of their default network security plans to discover and rectify rogue devices, adversaries, and services that may be on the network. This increased network visibility will allow operational technology cybersecurity practitioners to improve their situational awareness of networks and their vulnerabilities.« less

Texture classification of normal tissues in computed tomography using Gabor filters

NASA Astrophysics Data System (ADS)

Dettori, Lucia; Bashir, Alia; Hasemann, Julie

2007-03-01

The research presented in this article is aimed at developing an automated imaging system for classification of normal tissues in medical images obtained from Computed Tomography (CT) scans. Texture features based on a bank of Gabor filters are used to classify the following tissues of interests: liver, spleen, kidney, aorta, trabecular bone, lung, muscle, IP fat, and SQ fat. The approach consists of three steps: convolution of the regions of interest with a bank of 32 Gabor filters (4 frequencies and 8 orientations), extraction of two Gabor texture features per filter (mean and standard deviation), and creation of a Classification and Regression Tree-based classifier that automatically identifies the various tissues. The data set used consists of approximately 1000 DIACOM images from normal chest and abdominal CT scans of five patients. The regions of interest were labeled by expert radiologists. Optimal trees were generated using two techniques: 10-fold cross-validation and splitting of the data set into a training and a testing set. In both cases, perfect classification rules were obtained provided enough images were available for training (~65%). All performance measures (sensitivity, specificity, precision, and accuracy) for all regions of interest were at 100%. This significantly improves previous results that used Wavelet, Ridgelet, and Curvelet texture features, yielding accuracy values in the 85%-98% range The Gabor filters' ability to isolate features at different frequencies and orientations allows for a multi-resolution analysis of texture essential when dealing with, at times, very subtle differences in the texture of tissues in CT scans.

Use of infrared imaging to predict the developmental stages and differences in chicken embryos exposed to different photoperiods

NASA Astrophysics Data System (ADS)

Frederick, Rebecca A.; Hsieh, Sheng-Jen; Palomares, Benjamin Giron

2012-06-01

Monitoring development of chicken embryos allows determination of when an egg is not developing and when eggs are close to hatching for more efficient production. Research has been conducted on the effects of temperature fluctuations and light exposure on embryo development; similarities between chicken and mammal embryos; and the use of MRI, tomography, and ultrasound to view specific areas and processes within the embryo. However, there has been little exploration of the use of infrared imaging as a non-destructive method for analyzing and predicting embryonic development. In this study, we built an automated loading system for image acquisition. Pilot experiments were conducted to determine the overall scanning time and scanning frequency. A batch of fertilized eggs was scanned each day as the embryos continued to grow. The captured images were analyzed and categorized into three stages: Stage 1 (days 1 to 7), Stage 2 (days 8 to 14), and Stage 3 (days 15 to 21). The temperature data abstracted from the captured images were divided into two groups. Group 1, consisting of two-thirds of the data, was used to construct a model. Group 2, consisting of one-third of the data, was used to evaluate the predictive accuracy of the model. A three-layer artificial neural network model was developed to predict embryo development stage given a temperature profile. Results suggest that the neural network model is sufficient to predict embryo development stage with good accuracy of 75%. Accuracy can likely be improved if more data sets for each development stage are available.

TU-CD-207-05: A Novel Digital Tomosynthesis System Using Orthogonal Scanning Technique: A Feasibility Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, J; Park, C; Kauweloa, K

2015-06-15

Purpose: As an alternative to full tomographic imaging technique such as cone-beam computed tomography (CBCT), there is growing interest to adopt digital tomosynthesis (DTS) for the use of diagnostic as well as therapeutic applications. The aim of this study is to propose a new DTS system using novel orthogonal scanning technique, which can provide superior image quality DTS images compared to the conventional DTS scanning system. Methods: Unlike conventional DTS scanning system, the proposed DTS is reconstructed with two sets of orthogonal patient scans. 1) X-ray projections that are acquired along transverse trajectory and 2) an additional sets of X-raymore » projections acquired along the vertical direction at the mid angle of the previous transverse scan. To reconstruct DTS, we have used modified filtered backprojection technique to account for the different scanning directions of each projection set. We have evaluated the performance of our method using numerical planning CT data of liver cancer patient and a physical pelvis phantom experiment. The results were compared with conventional DTS techniques with single transverse and vertical scanning. Results: The experiments on both numerical simulation as well as physical experiment showed that the resolution as well as contrast of anatomical structures was much clearer using our method. Specifically, the image quality comparing with transversely scanned DTS showed that the edge and contrast of anatomical structures along Left-Right (LR) directions was comparable however, considerable discrepancy and enhancement could be observed along Superior-Inferior (SI) direction using our method. The opposite was observed when vertically scanned DTS was compared. Conclusion: In this study, we propose a novel DTS system using orthogonal scanning technique. The results indicated that the image quality of our novel DTS system was superior compared to conventional DTS system. This makes our DTS system potentially useful in various on-line clinical applications.« less

Full-field ultrasonic inspection for a composite sandwich plate skin-core debonding detection using laser-based ultrasonics

NASA Astrophysics Data System (ADS)

Chong, See Yenn; Victor, Jared J.; Todd, Michael D.

2017-04-01

In this paper, a full-field ultrasonic guided wave method is proposed to inspect a composite sandwich specimen made for an aircraft engine nacelle. The back skin/core interface of the specimen is built with two fabricated disbond defects (diameters of 12.7 mm and 25.4 mm) by removing areas of the adhesive used to bond the back skin to the core. A laser ultrasonic interrogation system (LUIS) incorporated with a disbond detection algorithm is developed. The system consists of a 1-kHz laser ultrasonic scanning system and a single fixed ultrasonic sensor to interrogate ultrasonic guided waves in the sandwich specimen. The interest area of 400 mm × 400 mm is scanned at a 0.5 mm scan interval. The corresponding full-field ultrasonic data is obtained and generated in the three-dimensional (3-D) space-time domain. Then, the 3-D full-field ultrasonic data is Fourier transformed and the ultrasonic frequency spectra are analyzed to determine the dominant frequency that is sensitive to the disbond defects. Continuous wavelet transform (CWT) based on fast Fourier transform (FFT) is implemented as a single-frequency bandpass filter to filter the full-field ultrasonic data in the 3-D space-time domain at the selected dominant frequency. The LUIS has shown the ability to detect the disbond with diameters of 11 mm and 23 mm which match to the pre-determined disbond sizes well. For future research, a robust signal processing algorithm and a model-based matched filter will be investigated to make the detection process autonomous and improve detectability

A speech-controlled environmental control system for people with severe dysarthria.

PubMed

Hawley, Mark S; Enderby, Pam; Green, Phil; Cunningham, Stuart; Brownsell, Simon; Carmichael, James; Parker, Mark; Hatzis, Athanassios; O'Neill, Peter; Palmer, Rebecca

2007-06-01

Automatic speech recognition (ASR) can provide a rapid means of controlling electronic assistive technology. Off-the-shelf ASR systems function poorly for users with severe dysarthria because of the increased variability of their articulations. We have developed a limited vocabulary speaker dependent speech recognition application which has greater tolerance to variability of speech, coupled with a computerised training package which assists dysarthric speakers to improve the consistency of their vocalisations and provides more data for recogniser training. These applications, and their implementation as the interface for a speech-controlled environmental control system (ECS), are described. The results of field trials to evaluate the training program and the speech-controlled ECS are presented. The user-training phase increased the recognition rate from 88.5% to 95.4% (p<0.001). Recognition rates were good for people with even the most severe dysarthria in everyday usage in the home (mean word recognition rate 86.9%). Speech-controlled ECS were less accurate (mean task completion accuracy 78.6% versus 94.8%) but were faster to use than switch-scanning systems, even taking into account the need to repeat unsuccessful operations (mean task completion time 7.7s versus 16.9s, p<0.001). It is concluded that a speech-controlled ECS is a viable alternative to switch-scanning systems for some people with severe dysarthria and would lead, in many cases, to more efficient control of the home.

Development of a MeV proton beam irradiation system.

PubMed

Park, Bum-Sik; Cho, Yong-Sub; Hong, In-Seok

2008-02-01

A proton beam irradiation system for the application of the MeV class proton beam, such as an implantation for a power semiconductor device and a smart-cut technology for a semiconductor production process, has been developed. This system consists of a negative ion source, an Einzel lens for a low energy beam transport, accelerating tubes, a gas stripper, a Cockroft-Walton high voltage power supply with 1 MV, a vacuum pumping system, and a high pressure insulating gas system. The negative hydrogen ion source is based on TRIUMF's design. Following the tandem accelerator, a pair of magnets is installed for raster scanning of the MeV proton beam to obtain a uniform irradiation pattern on the target. The system is 7 m long from the ion source to the target and is optimized for the proton beam irradiation. The details of the system development will be described.

Design of high-performance adaptive objective lens with large optical depth scanning range for ultrabroad near infrared microscopic imaging

PubMed Central

Lan, Gongpu; Mauger, Thomas F.; Li, Guoqiang

2015-01-01

We report on the theory and design of adaptive objective lens for ultra broadband near infrared light imaging with large dynamic optical depth scanning range by using an embedded tunable lens, which can find wide applications in deep tissue biomedical imaging systems, such as confocal microscope, optical coherence tomography (OCT), two-photon microscopy, etc., both in vivo and ex vivo. This design is based on, but not limited to, a home-made prototype of liquid-filled membrane lens with a clear aperture of 8mm and the thickness of 2.55mm ~3.18mm. It is beneficial to have an adaptive objective lens which allows an extended depth scanning range larger than the focal length zoom range, since this will keep the magnification of the whole system, numerical aperture (NA), field of view (FOV), and resolution more consistent. To achieve this goal, a systematic theory is presented, for the first time to our acknowledgment, by inserting the varifocal lens in between a front and a back solid lens group. The designed objective has a compact size (10mm-diameter and 15mm-length), ultrabroad working bandwidth (760nm - 920nm), a large depth scanning range (7.36mm in air) — 1.533 times of focal length zoom range (4.8mm in air), and a FOV around 1mm × 1mm. Diffraction-limited performance can be achieved within this ultrabroad bandwidth through all the scanning depth (the resolution is 2.22 μm - 2.81 μm, calculated at the wavelength of 800nm with the NA of 0.214 - 0.171). The chromatic focal shift value is within the depth of focus (field). The chromatic difference in distortion is nearly zero and the maximum distortion is less than 0.05%. PMID:26417508

Ultrasonic scanning system for in-place inspection of brazed tube joints

NASA Technical Reports Server (NTRS)

Haynes, J. L.; Wages, C. G.; Haralson, H. S. (Inventor)

1973-01-01

A miniaturized ultrasonic scanning system for nondestructive in-place, non-immersion testing of brazed joints in stainless-steel tubing is described. The system is capable of scanning brazed tube joints, with limited clearance access, in 1/4 through 5/8 inch union, tee, elbow and cross configurations. The system has the capability to detect defective conditions now associated with material density changes in addition to those which are depended upon density variations. The system includes a miniaturized scanning head assembly that fits around a tube joint and rotates the transducer around and down the joint in a continuous spiral motion. The C-scan recorder is similar in principle to conventional models except that it was specially designed to track the continuous spiral scan of the tube joint. The scanner and recorder can be operated with most commercially available ultrasonic flaw detectors.

Performance comparison between the high-speed Yokogawa spinning disc confocal system and single-point scanning confocal systems.

PubMed

Wang, E; Babbey, C M; Dunn, K W

2005-05-01

Fluorescence microscopy of the dynamics of living cells presents a special challenge to a microscope imaging system, simultaneously requiring both high spatial resolution and high temporal resolution, but with illumination levels low enough to prevent fluorophore damage and cytotoxicity. We have compared the high-speed Yokogawa CSU10 spinning disc confocal system with several conventional single-point scanning confocal (SPSC) microscopes, using the relationship between image signal-to-noise ratio and fluorophore photobleaching as an index of system efficiency. These studies demonstrate that the efficiency of the CSU10 consistently exceeds that of the SPSC systems. The high efficiency of the CSU10 means that quality images can be collected with much lower levels of illumination; the CSU10 was capable of achieving the maximum signal-to-noise of an SPSC system at illumination levels that incur only at 1/15th of the rate of the photobleaching of the SPSC system. Although some of the relative efficiency of the CSU10 system may be attributed to the use of a CCD rather than a photomultiplier detector system, our analyses indicate that high-speed imaging with the SPSC system is limited by fluorescence saturation at the high levels of illumination frequently needed to collect images at high frame rates. The high speed, high efficiency and freedom from fluorescence saturation combine to make the CSU10 effective for extended imaging of living cells at rates capable of capturing the three-dimensional motion of endosomes moving up to several micrometres per second.

On the consistency among different approaches for nuclear track scanning and data processing

NASA Astrophysics Data System (ADS)

Inozemtsev, K. O.; Kushin, V. V.; Kodaira, S.; Shurshakov, V. A.

2018-04-01

The article describes various approaches for space radiation track measurement using CR-39™ detector (Tastrak). The results of comparing different methods for track scanning and data processing are presented. Basic algorithms for determination of track parameters are described. Every approach involves individual set of measured track parameters. For two sets, track scanning is sufficient in the plane of detector surface (2-D measurement), third set requires scanning in the additional projection (3-D measurement). An experimental comparison of considered techniques was made with the use of accelerated heavy ions Ar, Fe and Kr.

Two-wavelength backscattering lidar for stand off detection of aerosols

NASA Astrophysics Data System (ADS)

Mierczyk, Zygmunt; Zygmunt, Marek; Gawlikowski, Andrzej; Gietka, Andrzej; Kaszczuk, Miroslawa; Knysak, Piotr; Mlodzianko, Andrzej; Muzal, Michal; Piotrowski, Wiesław; Wojtanowski, Jacek

2008-10-01

Following article presents LIDAR for stand off detection of aerosols which was constructed in Institute of Optoelectronics in Military University of Technology. LIDAR is a DISC type system (DIfferential SCattering) and is based on analysis of backscattering signal for two wavelengths (λ1 = 1064 nm and λ2 = 532 nm) - the first and the second harmonic of Nd:YAG laser. Optical receiving system is consisted of aspherical mirror lens, two additional mirrors and a system of interference filters. In detection system of LIDAR a silicon avalanche photodiode and two different amplifiers were used. Whole system is mounted on a specialized platform designed for possibility of LIDAR scanning movements. LIDAR is computer controlled. The compiled software enables regulation of the scanning platform work, gain control, and control of data processing and acquisition system. In the article main functional elements of LIDAR are shown and typical parameters of system work and construction are presented. One presented also first results of research with use of LIDAR. The aim of research was to detect and characterize scattering aerosol, both natural and anthropogenic one. For analyses of natural aerosols, cumulus cloud was used. For analyses of anthropogenic aerosols one used three various pyrotechnic mixtures (DM11, M2, M16) which generate smoke of different parameters. All scattering centers were firstly well described and theoretical analyses were conducted. Results of LIDAR research were compared with theoretical analyses and general conclusions concerning correctness of LIDAR work and its application were drawn.

Patient-specific dose estimation for pediatric abdomen-pelvis CT

NASA Astrophysics Data System (ADS)

Li, Xiang; Samei, Ehsan; Segars, W. Paul; Sturgeon, Gregory M.; Colsher, James G.; Frush, Donald P.

2009-02-01

The purpose of this study is to develop a method for estimating patient-specific dose from abdomen-pelvis CT examinations and to investigate dose variation across patients in the same weight group. Our study consisted of seven pediatric patients in the same weight/protocol group, for whom full-body computer models were previously created based on the patients' CT data obtained for clinical indications. Organ and effective dose of these patients from an abdomen-pelvis scan protocol (LightSpeed VCT scanner, 120-kVp, 85-90 mA, 0.4-s gantry rotation period, 1.375-pitch, 40-mm beam collimation, and small body scan field-of-view) was calculated using a Monte Carlo program previously developed and validated for the same CT system. The seven patients had effective dose of 2.4-2.8 mSv, corresponding to normalized effective dose of 6.6-8.3 mSv/100mAs (coefficient of variation: 7.6%). Dose variations across the patients were small for large organs in the scan coverage (mean: 6.6%; range: 4.9%-9.2%), larger for small organs in the scan coverage (mean: 10.3%; range: 1.4%-15.6%), and the largest for organs partially or completely outside the scan coverage (mean: 14.8%; range: 5.7%-27.7%). Normalized effective dose correlated strongly with body weight (correlation coefficient: r = -0.94). Normalized dose to the kidney and the adrenal gland correlated strongly with mid-liver equivalent diameter (kidney: r = -0.97; adrenal glands: r = -0.98). Normalized dose to the small intestine correlated strongly with mid-intestine equivalent diameter (r = -0.97). These strong correlations suggest that patient-specific dose may be estimated for any other child in the same size group who undergoes the abdomen-pelvis scan.

Augmenting Amyloid PET Interpretations With Quantitative Information Improves Consistency of Early Amyloid Detection.

PubMed

Harn, Nicholas R; Hunt, Suzanne L; Hill, Jacqueline; Vidoni, Eric; Perry, Mark; Burns, Jeffrey M

2017-08-01

Establishing reliable methods for interpreting elevated cerebral amyloid-β plaque on PET scans is increasingly important for radiologists, as availability of PET imaging in clinical practice increases. We examined a 3-step method to detect plaque in cognitively normal older adults, focusing on the additive value of quantitative information during the PET scan interpretation process. Fifty-five F-florbetapir PET scans were evaluated by 3 experienced raters. Scans were first visually interpreted as having "elevated" or "nonelevated" plaque burden ("Visual Read"). Images were then processed using a standardized quantitative analysis software (MIMneuro) to generate whole brain and region of interest SUV ratios. This "Quantitative Read" was considered elevated if at least 2 of 6 regions of interest had an SUV ratio of more than 1.1. The final interpretation combined both visual and quantitative data together ("VisQ Read"). Cohen kappa values were assessed as a measure of interpretation agreement. Plaque was elevated in 25.5% to 29.1% of the 165 total Visual Reads. Interrater agreement was strong (kappa = 0.73-0.82) and consistent with reported values. Quantitative Reads were elevated in 45.5% of participants. Final VisQ Reads changed from initial Visual Reads in 16 interpretations (9.7%), with most changing from "nonelevated" Visual Reads to "elevated." These changed interpretations demonstrated lower plaque quantification than those initially read as "elevated" that remained unchanged. Interrater variability improved for VisQ Reads with the addition of quantitative information (kappa = 0.88-0.96). Inclusion of quantitative information increases consistency of PET scan interpretations for early detection of cerebral amyloid-β plaque accumulation.

Magnetic particle-scanning for ultrasensitive immunodetection on-chip.

PubMed

Cornaglia, Matteo; Trouillon, Raphaël; Tekin, H Cumhur; Lehnert, Thomas; Gijs, Martin A M

2014-08-19

We describe the concept of magnetic particle-scanning for on-chip detection of biomolecules: a magnetic particle, carrying a low number of antigens (Ag's) (down to a single molecule), is transported by hydrodynamic forces and is subjected to successive stochastic reorientations in an engineered magnetic energy landscape. The latter consists of a pattern of substrate-bound small magnetic particles that are functionalized with antibodies (Ab's). Subsequationuent counting of the captured Ag-carrying particles provides the detection signal. The magnetic particle-scanning principle is investigated in a custom-built magneto-microfluidic chip and theoretically described by a random walk-based model, in which the trajectory of the contact point between an Ag-carrying particle and the small magnetic particle pattern is described by stochastic moves over the surface of the mobile particle, until this point coincides with the position of an Ag, resulting in the binding of the particle. This model explains the particular behavior of previously reported experimental dose-response curves obtained for two different ligand-receptor systems (biotin/streptavidin and TNF-α) over a wide range of concentrations. Our model shows that magnetic particle-scanning results in a very high probability of immunocomplex formation for very low Ag concentrations, leading to an extremely low limit of detection, down to the single molecule-per-particle level. When compared to other types of magnetic particle-based surface coverage assays, our strategy was found to offer a wider dynamic range (>8 orders of magnitude), as the system does not saturate for concentrations as high as 10(11) Ag molecules in a 5 μL drop. Furthermore, by emphasizing the importance of maximizing the encounter probability between the Ag and the Ab to improve sensitivity, our model also contributes to explaining the behavior of other particle-based heterogeneous immunoassays.

A rigid motion correction method for helical computed tomography (CT)

NASA Astrophysics Data System (ADS)

Kim, J.-H.; Nuyts, J.; Kyme, A.; Kuncic, Z.; Fulton, R.

2015-03-01

We propose a method to compensate for six degree-of-freedom rigid motion in helical CT of the head. The method is demonstrated in simulations and in helical scans performed on a 16-slice CT scanner. Scans of a Hoffman brain phantom were acquired while an optical motion tracking system recorded the motion of the bed and the phantom. Motion correction was performed by restoring projection consistency using data from the motion tracking system, and reconstructing with an iterative fully 3D algorithm. Motion correction accuracy was evaluated by comparing reconstructed images with a stationary reference scan. We also investigated the effects on accuracy of tracker sampling rate, measurement jitter, interpolation of tracker measurements, and the synchronization of motion data and CT projections. After optimization of these aspects, motion corrected images corresponded remarkably closely to images of the stationary phantom with correlation and similarity coefficients both above 0.9. We performed a simulation study using volunteer head motion and found similarly that our method is capable of compensating effectively for realistic human head movements. To the best of our knowledge, this is the first practical demonstration of generalized rigid motion correction in helical CT. Its clinical value, which we have yet to explore, may be significant. For example it could reduce the necessity for repeat scans and resource-intensive anesthetic and sedation procedures in patient groups prone to motion, such as young children. It is not only applicable to dedicated CT imaging, but also to hybrid PET/CT and SPECT/CT, where it could also ensure an accurate CT image for lesion localization and attenuation correction of the functional image data.

Morphomics of the Talus.

PubMed

Gorman, David; Handy, Ebram; Wang, Sikui; Irwin, Annette L; Wang, Stewart

2016-11-01

Previous studies of frontal crash databases reported that ankle fractures are among the most common lower extremity fractures. While not generally life threatening, these injuries can be debilitating. Laboratory research into the mechanisms of ankle fractures has linked dorsiflexion with an increased risk of tibia and fibula malleolus fractures. However, talus fractures were not produced in the laboratory tests and appear to be caused by more complex loading of the joint. In this study, an analysis of the National Automotive Sampling System - Crashworthiness Data System (NASS-CDS) for the years 2004-2013 was conducted to investigate foot-ankle injury rates in front seat occupants involved in frontal impact crashes. A logistic regression model was developed indicating occupant weight, impact delta velocity and gender to be significant predictors of talus fracture (p<0.05). Separately, a specific set of Computed Tomography (CT) scans from the International Center for Automotive Medicine (ICAM) scan database was used to characterize the talar dome. This control population consisted of 207 adults aged 18 to 84, with no foot or ankle trauma, and scans that had suitable coverage of the talus. Size of the talus was determined using medial-to-lateral width and anterior-to-posterior depth measurements. Geometry was assessed by evaluating the radius of the articulating talus and strength was assessed using a combination of cross sectional area and density. Demographics were studied to investigate correlation with talus measurements from the CT scan database. A multi-variable linear regression model of the morphomics showed gender to be statistically significant (p<0.05) for talus depth, width, cross-sectional area, radius and strength. Body Mass Index (BMI) was significant for depth and radius. Weight was significant for depth, width, density and strength. Stature was significant for depth, cross-sectional area, radius and strength. Age was significant for radius and density.

TDRS-L Pre-Launch Press Conference

NASA Image and Video Library

2014-01-21

CAPE CANAVERAL, Fla. –During a news conference at NASA's Kennedy Space Center in Florida, agency and contractor officials discussed preparations for the launch of NASA's Tracking and Data Relay Satellite, or TDRS-L, spacecraft. Participating in the briefing, from the left, are Badri Younes, deputy associate administrator, Space Communications and Navigation SCaN NASA Human Exploration and Operations Mission Directorate at NASA Headquarters in Washington D.C., Tim Dunn, NASA launch director at Kennedy, Vernon Thorp, program manager for NASA Missions with United Launch Alliance in Denver, Colo., Jeffrey Gramling, NASA's TDRS-L project manager at the Goddard Space Flight Center in Greenbelt, Md., Andy Kopito, Civil Space Programs director for Boeing Space & Intelligence Systems in El Segundo, Calif., and Clay Flinn, launch weather officer for the 45th Weather Squadron at Cape Canaveral Air Force Station, Fla. The TDRS-L spacecraft is the second of three new satellites designed to ensure vital operational continuity for NASA by expanding the lifespan of the Tracking and Data Relay Satellite System TDRSS fleet, which consists of eight satellites in geosynchronous orbit. The spacecraft provide tracking, telemetry, command and high bandwidth data return services for numerous science and human exploration missions orbiting Earth. These include NASA's Hubble Space Telescope and the International Space Station. TDRS-L has a high-performance solar panel designed for more spacecraft power to meet the growing S-band communications requirements. TDRSS is one of NASA Space Communication and Navigation’s SCaN three networks providing space communications to NASA’s missions. For more information more about TDRS-L, visit: http://www.nasa.gov/tdrs To learn more about SCaN, visit: www.nasa.gov/scan Photo credit: NASA/Frankie Martin

TDRS-L Pre-Launch Press Conference

NASA Image and Video Library

2014-01-21

CAPE CANAVERAL, Fla. –During a news conference at NASA's Kennedy Space Center in Florida, agency and contractor officials discussed preparations for the launch of NASA's Tracking and Data Relay Satellite, or TDRS-L, spacecraft. Participating in the briefing, from the left, are George Diller of NASA Public Affairs, Badri Younes, deputy associate administrator, Space Communications and Navigation SCaN NASA Human Exploration and Operations Mission Directorate at NASA Headquarters in Washington D.C., Tim Dunn, NASA launch director at Kennedy, Vernon Thorp, program manager for NASA Missions with United Launch Alliance in Denver, Colo., Jeffrey Gramling, NASA's TDRS-L project manager at the Goddard Space Flight Center in Greenbelt, Md., Andy Kopito, Civil Space Programs director for Boeing Space & Intelligence Systems in El Segundo, Calif., and Clay Flinn, launch weather officer for the 45th Weather Squadron at Cape Canaveral Air Force Station, Fla. The TDRS-L spacecraft is the second of three new satellites designed to ensure vital operational continuity for NASA by expanding the lifespan of the Tracking and Data Relay Satellite System TDRSS fleet, which consists of eight satellites in geosynchronous orbit. The spacecraft provide tracking, telemetry, command and high bandwidth data return services for numerous science and human exploration missions orbiting Earth. These include NASA's Hubble Space Telescope and the International Space Station. TDRS-L has a high-performance solar panel designed for more spacecraft power to meet the growing S-band communications requirements. TDRSS is one of NASA Space Communication and Navigation’s SCaN three networks providing space communications to NASA’s missions. For more information more about TDRS-L, visit: http://www.nasa.gov/tdrs To learn more about SCaN, visit: www.nasa.gov/scan Photo credit: NASA/Frankie Martin

Efficacy of 67 gallium ECT imaging in lymphoma, infection, and lung carcinoma: A comparison with planar imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harwood, S.J.; Anderson, M.W.; Klein, R.C.

1984-01-01

Emission computed tomography (ECT) studies were performed on a GE 400 A/T camera and ADAC computers (system 3 and system 3300). Thirty-three sets of ECT and planar images were obtained in 20 patients over a six month period. Imaging was performed 48 hours after the intravenous administration of 5 mc of Gallium 67 citrate. No bowel preparation was employed. Comparison is made of the initial nuclear medicine report derived from planar and ECT imaging aided by clinical knowledge versus the consensus opinion of two nuclear medicine physicians reading the planar images along with minimal clinical information. The lymphoma series consistsmore » of 18 scans in 10 patients. There were 5 scans in which a false negative planar interpretation was changed to a true positive ECT interpretation. Sensitivity of planar imaging for lymphoma was 58% which rose to 100% with addition of ECT information. There were no false positives by either technique. There were 5 sets of scans in 5 lung carcinoma patients. Sensitivity of the planar images was 60% because of 2 false negative results. Sensitivity of the ECT technique was 100%. There were no false positives. The infection series consists of 10 scans in 5 patients. Sensitivity of ECT was 100%, sensitivity of planar was 66%. There was 1 false positive planar. For the total series the accuracy of planar imaging was 69% and the predictive value of a negative planar interpretation was 44%. Corresponding values for ECT imaging were 100%. The authors' experience demonstrates significant increase in sensitivity without loss of specificity resulting from the use of Emission Computed Tomography in both chest and abdomen in patients with lymphoma, infection, and lung cancer.« less

Application of Intra-Oral Dental Scanners in the Digital Workflow of Implantology

PubMed Central

van der Meer, Wicher J.; Andriessen, Frank S.; Wismeijer, Daniel; Ren, Yijin

2012-01-01

Intra-oral scanners will play a central role in digital dentistry in the near future. In this study the accuracy of three intra-oral scanners was compared. Materials and methods: A master model made of stone was fitted with three high precision manufactured PEEK cylinders and scanned with three intra-oral scanners: the CEREC (Sirona), the iTero (Cadent) and the Lava COS (3M). In software the digital files were imported and the distance between the centres of the cylinders and the angulation between the cylinders was assessed. These values were compared to the measurements made on a high accuracy 3D scan of the master model. Results: The distance errors were the smallest and most consistent for the Lava COS. The distance errors for the Cerec were the largest and least consistent. All the angulation errors were small. Conclusions: The Lava COS in combination with a high accuracy scanning protocol resulted in the smallest and most consistent errors of all three scanners tested when considering mean distance errors in full arch impressions both in absolute values and in consistency for both measured distances. For the mean angulation errors, the Lava COS had the smallest errors between cylinders 1–2 and the largest errors between cylinders 1–3, although the absolute difference with the smallest mean value (iTero) was very small (0,0529°). An expected increase in distance and/or angular errors over the length of the arch due to an accumulation of registration errors of the patched 3D surfaces could be observed in this study design, but the effects were statistically not significant. Clinical relevance For making impressions of implant cases for digital workflows, the most accurate scanner with the scanning protocol that will ensure the most accurate digital impression should be used. In our study model that was the Lava COS with the high accuracy scanning protocol. PMID:22937030

A microprocessor controlled pressure scanning system

NASA Technical Reports Server (NTRS)

Anderson, R. C.

1976-01-01

A microprocessor-based controller and data logger for pressure scanning systems is described. The microcomputer positions and manages data from as many as four 48-port electro-mechanical pressure scanners. The maximum scanning rate is 80 pressure measurements per second (20 ports per second on each of four scanners). The system features on-line calibration, position-directed data storage, and once-per-scan display in engineering units of data from a selected port. The system is designed to be interfaced to a facility computer through a shared memory. System hardware and software are described. Factors affecting measurement error in this type of system are also discussed.

Control electronics for a multi-laser/multi-detector scanning system

NASA Technical Reports Server (NTRS)

Kennedy, W.

1980-01-01

The Mars Rover Laser Scanning system uses a precision laser pointing mechanism, a photodetector array, and the concept of triangulation to perform three dimensional scene analysis. The system is used for real time terrain sensing and vision. The Multi-Laser/Multi-Detector laser scanning system is controlled by a digital device called the ML/MD controller. A next generation laser scanning system, based on the Level 2 controller, is microprocessor based. The new controller capabilities far exceed those of the ML/MD device. The first draft circuit details and general software structure are presented.

Optical air-coupled NDT system with ultra-broad frequency bandwidth (Conference Presentation)

NASA Astrophysics Data System (ADS)

Fischer, Balthasar; Rohringer, Wolfgang; Heine, Thomas

2017-05-01

We present a novel, optical ultrasound airborne acoustic testing setup exhibiting a frequency bandwidth of 1MHz in air. The sound waves are detected by a miniaturized Fabry-Pérot interferometer (2mm cavity) whilst the sender consists of a thermoacoustic emitter or a short laser pulse We discuss characterization measurements and C-scans of a selected set of samples, including Carbon fiber reinforced polymer (CFRP). The high detector sensitivity allows for an increased penetration depth. The high frequency and the small transducer dimensions lead to a compelling image resolution.

Plain and Rolled Images from Paired Fingerprint Cards

National Institute of Standards and Technology Data Gateway

NIST Plain and Rolled Images from Paired Fingerprint Cards (Web, free access)   NIST Special Database 29 is being distributed for use in development and testing fingerprint matching systems. The data consist of 216 ten-print fingerprint card pairs with both the rolled and plains (from a bottom of the fingerprint card) scanned at 19.7 pixels per mm. A newer version of the compression/decompression software on the CDROM can be found at the website http://www.nist.gov/itl/iad/ig/nigos.cfm as part of the NBIS package.

Carbon nanotube oscillator surface profiling device and method of use

DOEpatents

Popescu, Adrian [Tampa, FL; Woods, Lilia M [Tampa, FL; Bondarev, Igor V [Fuquay Varina, NC

2011-11-15

The proposed device is based on a carbon nanotube oscillator consisting of a finite length outer stationary nanotube and a finite length inner oscillating nanotube. Its main function is to measure changes in the characteristics of the motion of the carbon nanotube oscillating near a sample surface, and profile the roughness of this surface. The device operates in a non-contact mode, thus it can be virtually non-wear and non-fatigued system. It is an alternative to the existing atomic force microscope (AFM) tips used to scan surfaces to determine their roughness.

Automatic Rotational Sky Quality Meter (R-SQM) Design and Software for Astronomical Observatories

NASA Astrophysics Data System (ADS)

Dogan, E.; Ozbaldan, E. E.; Shameoni, Niaei M.; Yesilyaprak, C.

2016-12-01

We have presented the new design of Sky Quality Meter (SQM) device that is an automatic rotational model of sky quality meter (R-SQM) carried out by DAG (Eastern Anatolia Observatory) Technical Team. R-SQM is required for determining the long-term changes of sky quality of an astronomical observatory and consists of four SQM devices mounted on a rotating shaft with different angles for scanning all sky. This system is controlled by a Raspberry Pi control card and a step motor with its driver and a special software.

Integral force feedback control with input shaping: Application to piezo-based scanning systems in ECDLs.

PubMed

Zhang, Meng; Liu, Zhigang; Zhu, Yu; Bu, Mingfan; Hong, Jun

2017-07-01

In this paper, a hybrid control system is developed by integrating the closed-loop force feedback and input shaping method to overcome the problem of the hysteresis and dynamic behavior in piezo-based scanning systems and increase the scanning speed of tunable external cavity diode lasers. The flexible hinge and piezoelectric actuators are analyzed, and a dynamic model of the scanning systems is established. A force sensor and an integral controller are utilized in integral force feedback (IFF) to directly augment the damping of the piezoelectric scanning systems. Hysteresis has been effectively eliminated, but the mechanical resonance is still evident. Noticeable residual vibration occurred after the inflection points and then gradually disappeared. For the further control of mechanical resonance, based on the theory of minimum-acceleration trajectory planning, the time-domain input shaping method was developed. The turning sections of a scanning trajectory are replaced by smooth curves, while the linear sections are retained. The IFF method is combined with the input shaping method to control the non-linearity and mechanical resonance in high-speed piezo-based scanning systems. Experiments are conducted, and the results demonstrate the effectiveness of the proposed control approach.

Integral force feedback control with input shaping: Application to piezo-based scanning systems in ECDLs

NASA Astrophysics Data System (ADS)

Zhang, Meng; Liu, Zhigang; Zhu, Yu; Bu, Mingfan; Hong, Jun

2017-07-01

In this paper, a hybrid control system is developed by integrating the closed-loop force feedback and input shaping method to overcome the problem of the hysteresis and dynamic behavior in piezo-based scanning systems and increase the scanning speed of tunable external cavity diode lasers. The flexible hinge and piezoelectric actuators are analyzed, and a dynamic model of the scanning systems is established. A force sensor and an integral controller are utilized in integral force feedback (IFF) to directly augment the damping of the piezoelectric scanning systems. Hysteresis has been effectively eliminated, but the mechanical resonance is still evident. Noticeable residual vibration occurred after the inflection points and then gradually disappeared. For the further control of mechanical resonance, based on the theory of minimum-acceleration trajectory planning, the time-domain input shaping method was developed. The turning sections of a scanning trajectory are replaced by smooth curves, while the linear sections are retained. The IFF method is combined with the input shaping method to control the non-linearity and mechanical resonance in high-speed piezo-based scanning systems. Experiments are conducted, and the results demonstrate the effectiveness of the proposed control approach.

Viewing-zone scanning holographic display using a MEMS spatial light modulator.

PubMed

Takaki, Yasuhiro; Fujii, Keisuke

2014-10-06

Horizontally scanning holography using a spatial light modulator based on microelectromechanical system, which we previously proposed for enlarging both the screen size and the viewing zone, utilized a screen scanning system with elementary holograms being scanned horizontally on the screen. In this study, to enlarge the screen size and the viewing zone, we propose a viewing-zone scanning system with enlarged hologram screen and horizontally scanned reduced viewing zone. The reduced viewing zone is localized using converging light emitted from the screen, and the entire screen can be viewed from the localized viewing zone. An experimental system was constructed, and we demonstrated the generation of reconstructed images with a screen size of 2.0 in, a viewing zone width of 437 mm at a distance of 600 mm from the screen, and a frame rate of 60 Hz.

Boresight alignment method for mobile laser scanning systems

NASA Astrophysics Data System (ADS)

Rieger, P.; Studnicka, N.; Pfennigbauer, M.; Zach, G.

2010-06-01

Mobile laser scanning (MLS) is the latest approach towards fast and cost-efficient acquisition of 3-dimensional spatial data. Accurately evaluating the boresight alignment in MLS systems is an obvious necessity. However, recent systems available on the market may lack of suitable and efficient practical workflows on how to perform this calibration. This paper discusses an innovative method for accurately determining the boresight alignment of MLS systems by employing 3D laser scanners. Scanning objects using a 3D laser scanner operating in a 2D line-scan mode from various different runs and scan directions provides valuable scan data for determining the angular alignment between inertial measurement unit and laser scanner. Field data is presented demonstrating the final accuracy of the calibration and the high quality of the point cloud acquired during an MLS campaign.

Establishing an Environmental Scanning/Forecasting System to Augment College and University Planning.

ERIC Educational Resources Information Center

Morrison, James L.

1987-01-01

The major benefit of an environmental scanning/forecasting system is in providing critical information for strategic planning. Such a system allows the institution to detect social, technological, economic, and political trends and potential events. The environmental scanning database developed by United Way of America is described. (MLW)

Fast ultra-wideband microwave spectral scanning utilizing photonic wavelength- and time-division multiplexing.

PubMed

Li, Yihan; Kuse, Naoya; Fermann, Martin

2017-08-07

A high-speed ultra-wideband microwave spectral scanning system is proposed and experimentally demonstrated. Utilizing coherent dual electro-optical frequency combs and a recirculating optical frequency shifter, the proposed system realizes wavelength- and time-division multiplexing at the same time, offering flexibility between scan speed and size, weight and power requirements (SWaP). High-speed spectral scanning spanning from ~1 to 8 GHz with ~1.2 MHz spectral resolution is achieved experimentally within 14 µs. The system can be easily scaled to higher bandwidth coverage, faster scanning speed or finer spectral resolution with suitable hardware.

High rate tests of the photon detection system for the LHCb RICH Upgrade

NASA Astrophysics Data System (ADS)

Blago, M. P.; Keizer, F.

2017-12-01

The photon detection system for the LHCb RICH Upgrade consists of an array of multianode photomultiplier tubes (MaPMTs) read out by custom-built modular electronics. The behaviour of the whole chain was studied at CERN using a pulsed laser. Threshold scans were performed in order to study the MaPMT pulse-height spectra at high event rates and different photon intensities. The results show a reduction in photon detection efficiency at 900 V bias voltage, marked by a 20% decrease in the single-photon peak height, when increasing the event rate from 100 kHz to 20 MHz. This reduction was not observed at 1000 V bias voltage.

Initial performance results for high-aspect ratio gold MEMS deformable mirrors

NASA Astrophysics Data System (ADS)

Fernández, Bautista; Kubby, Joel

2009-02-01

The fabrication and initial performance results of high-aspect ratio 3-dimensional Micro-Electro-Mechanical System (MEMS) Deformable Mirrors (DM) for Adaptive Optics (AO) will be discussed. The DM systems were fabricated out of gold, and consist of actuators bonded to a continuous face sheet, with different boundary conditions. DM mirror displacements vs. voltage have been measured with a white light interferometer and the corresponding results compared to Finite Element Analysis (FEA) simulations. Interferometer scans of a DM have shown that ~9.4um of stroke can be achieved with low voltage, thus showing that this fabrication process holds promise in the manufacturing of future MEMS DM's for the next generation of extremely large telescopes.

Modeling and Characterization of the Magnetocaloric Effect in Ni2MnGa Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nicholson, Don M; Odbadrakh, Khorgolkhuu; Shassere, Benjamin

2014-01-01

Magnetic shape memory alloys have great promise as magneto-caloric effect refrigerant materials due to their combined magnetic and structural transitions. Computational and experimental research is reported on the Ni2MnGa material system. The magnetic states of this system are explored using the Wang-Landau statistical approach in conjunction with the Locally Self-consistent Multiple-Scattering method. The effects of alloying agents on the transition temperatures of the Ni2MnGa alloy are investigated using differential scanning calorimetry and superconducting quantum interference device. Experiments are performed at the Spallation Neutron Source at Oak Ridge National Laboratory to observe the structural and magnetic phase transformations.

Scanning MWCNT-Nanopipette and Probe Microscopy: Li Patterning and Transport Studies.

PubMed

Larson, Jonathan M; Bharath, Satyaveda C; Cullen, William G; Reutt-Robey, Janice E

2015-10-07

A carbon-nanotube-enabling scanning probe technique/nanotechnology for manipulating and measuring lithium at the nano/mesoscale is introduced. Scanning Li-nanopipette and probe microscopy (SLi-NPM) is based on a conductive atomic force microscope (AFM) cantilever with an open-ended multi-walled carbon nanotube (MWCNT) affixed to its apex. SLi-NPM operation is demonstrated with a model system consisting of a Li thin film on a Si(111) substrate. By control of bias, separation distance, and contact time, attograms of Li can be controllably pipetted to or from the MWCNT tip. Patterned surface Li features are then directly probed via noncontact AFM measurements with the MWCNT tip. The subsequent decay of Li features is simulated with a mesoscale continuum model, developed here. The Li surface diffusion coefficient for a four (two) Li layer thick film is measured as D=8(±1.2)×10(-15) cm(2) s(-1) (D=1.75(±0.15)×10(-15) cm(2) s(-1)). Dual-Li pipetting/measuring with SLi-NPM enables a broad range of time-dependent Li and nanoelectrode characterization studies of fundamental importance to energy-storage research. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A study on the theoretical and practical accuracy of conoscopic holography-based surface measurements: toward image registration in minimally invasive surgery†

PubMed Central

Burgner, J.; Simpson, A. L.; Fitzpatrick, J. M.; Lathrop, R. A.; Herrell, S. D.; Miga, M. I.; Webster, R. J.

2013-01-01

Background Registered medical images can assist with surgical navigation and enable image-guided therapy delivery. In soft tissues, surface-based registration is often used and can be facilitated by laser surface scanning. Tracked conoscopic holography (which provides distance measurements) has been recently proposed as a minimally invasive way to obtain surface scans. Moving this technique from concept to clinical use requires a rigorous accuracy evaluation, which is the purpose of our paper. Methods We adapt recent non-homogeneous and anisotropic point-based registration results to provide a theoretical framework for predicting the accuracy of tracked distance measurement systems. Experiments are conducted a complex objects of defined geometry, an anthropomorphic kidney phantom and a human cadaver kidney. Results Experiments agree with model predictions, producing point RMS errors consistently < 1 mm, surface-based registration with mean closest point error < 1 mm in the phantom and a RMS target registration error of 0.8 mm in the human cadaver kidney. Conclusions Tracked conoscopic holography is clinically viable; it enables minimally invasive surface scan accuracy comparable to current clinical methods that require open surgery. PMID:22761086

Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter.

PubMed

Lee, Hsiang-Chieh; Ahsen, Osman Oguz; Liang, Kaicheng; Wang, Zhao; Cleveland, Cody; Booth, Lucas; Potsaid, Benjamin; Jayaraman, Vijaysekhar; Cable, Alex E; Mashimo, Hiroshi; Langer, Robert; Traverso, Giovanni; Fujimoto, James G

2016-08-01

We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 µm axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 frames per second (fps) with a ~30 µm (FWHM) spot size. Volumetric imaging is achieved by proximal pullback of the micromotor assembly within the balloon at 1.5 mm/sec. Volumetric data consisting of 4200 circumferential images of 5,000 A-scans each over a 2.6 cm length, covering a ~13 cm(2) area is acquired in <18 seconds. A non-rigid image registration algorithm is used to suppress motion artifacts from non-uniform rotational distortion (NURD), cardiac motion or respiration. En face OCT images at various depths can be generated. OCT angiography (OCTA) is computed using intensity decorrelation between sequential pairs of circumferential scans and enables three-dimensional visualization of vasculature. Wide area volumetric OCT and OCTA imaging of the swine esophagus in vivo is demonstrated.

Knowledge-based automated technique for measuring total lung volume from CT

NASA Astrophysics Data System (ADS)

Brown, Matthew S.; McNitt-Gray, Michael F.; Mankovich, Nicholas J.; Goldin, Jonathan G.; Aberle, Denise R.

1996-04-01

A robust, automated technique has been developed for estimating total lung volumes from chest computed tomography (CT) images. The technique includes a method for segmenting major chest anatomy. A knowledge-based approach automates the calculation of separate volumes of the whole thorax, lungs, and central tracheo-bronchial tree from volumetric CT data sets. A simple, explicit 3D model describes properties such as shape, topology and X-ray attenuation, of the relevant anatomy, which constrain the segmentation of these anatomic structures. Total lung volume is estimated as the sum of the right and left lungs and excludes the central airways. The method requires no operator intervention. In preliminary testing, the system was applied to image data from two healthy subjects and four patients with emphysema who underwent both helical CT and pulmonary function tests. To obtain single breath-hold scans, the healthy subjects were scanned with a collimation of 5 mm and a pitch of 1.5, while the emphysema patients were scanned with collimation of 10 mm at a pitch of 2.0. CT data were reconstructed as contiguous image sets. Automatically calculated volumes were consistent with body plethysmography results (< 10% difference).

TDRS-L Liftoff

NASA Image and Video Library

2014-01-23

CAPE CANAVERAL, Fla. -- A United Launch Alliance Atlas V rocket streaks through the night sky over Space Launch Complex 41 at Cape Canaveral Air Force Station in Florida, carrying NASA's Tracking and Data Relay Satellite, or TDRS-L, to Earth orbit. Launch was at 9:33 p.m. EST Jan. 23 during a 40-minute launch window. The TDRS-L spacecraft is the second of three new satellites designed to ensure vital operational continuity for NASA by expanding the lifespan of the Tracking and Data Relay Satellite System TDRSS fleet, which consists of eight satellites in geosynchronous orbit. The spacecraft provide tracking, telemetry, command and high-bandwidth data return services for numerous science and human exploration missions orbiting Earth. These include NASA's Hubble Space Telescope and the International Space Station. TDRS-L has a high-performance solar panel designed for more spacecraft power to meet the growing S-band communications requirements. TDRSS is one of three NASA Space Communication and Navigation SCaN networks providing space communications to NASA’s missions. For more information more about TDRS-L, visit http://www.nasa.gov/tdrs. To learn more about SCaN, visit www.nasa.gov/scan. Photo credit: NASA/Kim Shiflett

A simple way to higher speed atomic force microscopy by retrofitting with a novel high-speed flexure-guided scanner

NASA Astrophysics Data System (ADS)

Ouma Alunda, Bernard; Lee, Yong Joong; Park, Soyeun

2018-06-01

A typical line-scan rate for a commercial atomic force microscope (AFM) is about 1 Hz. At such a rate, more than four minutes of scanning time is required to obtain an image of 256 × 256 pixels. Despite control electronics of most commercial AFMs permit faster scan rates, default piezoelectric X–Y scanners limit the overall speed of the system. This is a direct consequence of manufacturers choosing a large scan range over the maximum operating speed for a X–Y scanner. Although some AFM manufacturers offer reduced-scan area scanners as an option, the speed improvement is not significant because such scanners do not have large enough reduction in the scan range and are mainly targeted to reducing the overall cost of the AFM systems. In this article, we present a simple parallel-kinematic substitute scanner for a commercial atomic force microscope to afford a higher scanning speed with no other hardware or software upgrade to the original system. Although the scan area reduction is unavoidable, our modified commercial XE-70 AFM from Park Systems has achieved a line scan rate of over 50 Hz, more than 10 times faster than the original, unmodified system. Our flexure-guided X–Y scanner can be a simple drop-in replacement option for enhancing the speed of various aging atomic force microscopes.

Periodic disruptions induced by high repetition rate femtosecond pulses on magnesium-oxide-doped lithium niobate surfaces

NASA Astrophysics Data System (ADS)

Zhang, Shuanggen; Kan, Hongli; Zhai, Kaili; Ma, Xiurong; Luo, Yiming; Hu, Minglie; Wang, Qingyue

2017-02-01

In this paper, we demonstrate the periodic disruption formation on magnesium-oxide-doped lithium niobate surfaces by a femtosecond fiber laser system with wavelength and repetition rate of 1040 nm and 52 MHz, respectively. Three main experimental conditions, laser average power, scanning speed, and orientation of sample were systematically studied. In particular, the ablation morphologies of periodic disruptions under different crystal orientations were specifically researched. The result shows that such disruptions consisting of a bamboo-like inner structure appears periodically for focusing on the surface of X-, Y- and Z-cut wafers, which are formed by a rapid quenching of the material. Meanwhile, due to the anisotropic property, the bamboo-like inner structures consist of a cavity only arise from X- and Z-cut orientation.

Environmental scanning as a moderator of strategy-performance relationships: an empirical analysis of physical therapy facilities.

PubMed

Davis, Mark A; Miles, Grant; McDowell, William C

2008-05-01

To date, strategic management research in health care is largely confined to the acute care sector of the industry. This research examines the linkages among environmental scanning, competitive strategy and performance in physical therapy facilities. Nontrivial differences between acute and subacute care firms suggest the role of environmental scanning may change in non-acute care settings. Consistent with previous research, these results indicate that the frequency of internal and external scanning is related to the strategic orientation of physical therapy facilities. Contrary to the expectations, broader scope of scanning is positively related to an increasing market-focused and increasing efficiency strategic orientation. A key objective of the research is to test the impact of strategy/scanning alignment on facility performance. These findings support predictions on the moderating role of scanning activities in the strategy-performance relationship. However, a paradoxical pattern of results has possible implications for clinician managers in subacute care settings as well as the interpretation of scanning activities.

The Detection of Clusters with Spatial Heterogeneity

ERIC Educational Resources Information Center

Zhang, Zuoyi

2011-01-01

This thesis consists of two parts. In Chapter 2, we focus on the spatial scan statistics with overdispersion and Chapter 3 is devoted to the randomized permutation test for identifying local patterns of spatial association. The spatial scan statistic has been widely used in spatial disease surveillance and spatial cluster detection. To apply it, a…

Environmental Scan of Weight Bias Exposure in Primary Health Care Training Programs

ERIC Educational Resources Information Center

Russell-Mayhew, Shelly; Nutter, Sarah; Alberga, Angela; Jelinski, Susan; Ball, Geoff D. C.; Edwards, Alun; Oddie, Scott; Sharma, Arya M.; Pickering, Barbara; Forhan, Mary

2016-01-01

Negative attitudes and beliefs about individuals with obesity (also known as weight bias) have negative consequences for physical and mental health for individuals with obesity and impact the quality of care provided by health professionals. A preliminary environmental scan of college and university training programs was conducted consisting of 67…

External Scan 2000: Environmental Scan of the Greater Sacramento Area.

ERIC Educational Resources Information Center

Beachler, Judith

This document provides a summary of the social, economic, and political changes at state and national levels that affect the Los Rios Community College District (LRCCD) in California. LRCCD consists of American River College (ARC), Cosumnes River College (CRC), and Sacramento City College (SCC). Demographic trends show that Greater Sacramento is…

Beam Scanning Antenna with Wideband Broadside Radiation Based on Multilayered Substrate Integrated Waveguide Composite Right/Left-Handed Structure

NASA Astrophysics Data System (ADS)

Zhang, Qin; Wu, Guo-cheng; Wang, Guang-ming; Liang, Jian-gang; Gao, Xiang-jun

2017-01-01

In this paper, a novel multilayered substrate integrated waveguide (SIW) composite right/left-handed (CRLH) structure is proposed to design beam scanning antenna for wideband broadside radiation. The unit cell of the SIW-CRLH structure is formed by spiral interdigital fingers etched on the upper ground of SIW, and a parasitic patch beneath the slot, has a continuous change of phase constant from negative to positive value within its passband. The proposed beam scanning antenna, which consists of consists of 15 identical elementary cells of the SIW-CRLH, is simulated, fabricated and measured. According to the measured results, the proposed antenna not only realizes a continuous main beam scanning from backward -78° to forward +80° within the operating frequency range from 8.25 to 12.2 GHz, but also obtains the measured broadside gain of 11.5 dB with variation of 1.0 dB over the frequency range of 8.8-9.25 GHz (4.99 %). Besides, compared with the same works in the references, this one has the most wonderful performance.

[Clinical effect of three dimensional human body scanning system BurnCalc in the evaluation of burn wound area].

PubMed

Lu, J; Wang, L; Zhang, Y C; Tang, H T; Xia, Z F

2017-10-20

Objective: To validate the clinical effect of three dimensional human body scanning system BurnCalc developed by our research team in the evaluation of burn wound area. Methods: A total of 48 burn patients treated in the outpatient department of our unit from January to June 2015, conforming to the study criteria, were enrolled in. For the first 12 patients, one wound on the limbs or torso was selected from each patient. The stability of the system was tested by 3 attending physicians using three dimensional human body scanning system BurnCalc to measure the area of wounds individually. For the following 36 patients, one wound was selected from each patient, including 12 wounds on limbs, front torso, and side torso, respectively. The area of wounds was measured by the same attending physician using transparency tracing method, National Institutes of Health (NIH) Image J method, and three dimensional human body scanning system BurnCalc, respectively. The time for getting information of 36 wounds by three methods was recorded by stopwatch. The stability among the testers was evaluated by the intra-class correlation coefficient (ICC). Data were processed with randomized blocks analysis of variance and Bonferroni test. Results: (1) Wound area of patients measured by three physicians using three dimensional human body scanning system BurnCalc was (122±95), (121±95), and (123±96) cm(2,) respectively, and there was no statistically significant difference among them ( F =1.55, P >0.05). The ICC among 3 physicians was 0.999. (2) The wound area of limbs of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (84±50), (76±46), and (84±49) cm(2,) respectively. There was no statistically significant difference in the wound area of limbs of patients measured by transparency tracing method and three dimensional human body scanning system BurnCalc ( P >0.05). The wound area of limbs of patients measured by NIH Image J method was smaller than that measured by transparency tracing method and three dimensional human body scanning system BurnCalc (with P values below 0.05). There was no statistically significant difference in the wound area of front torso of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc ( F =0.33, P >0.05). The wound area of side torso of patients measured by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (169±88), (150±80), and (169±86) cm(2,) respectively. There was no statistically significant difference in the wound area of side torso of patients measured by transparency tracing method and three dimensional human body scanning system BurnCalc ( P >0.05). The wound area of side torso of patients measured by NIH Image J method was smaller than that measured by transparency tracing method and three dimensional human body scanning system BurnCalc (with P values below 0.05). (3) The time for getting information of wounds of patients by transparency tracing method, NIH Image J method, and three dimensional human body scanning system BurnCalc was (77±14), (10±3), and (9±3) s, respectively. The time for getting information of wounds of patients by transparency tracing method was longer than that by NIH Image J method and three dimensional human body scanning system BurnCalc (with P values below 0.05). The time for getting information of wounds of patients by three dimensional human body scanning system BurnCalc was close to that by NIH Image J method ( P >0.05). Conclusions: The three dimensional human body scanning system BurnCalc is stable and can accurately evaluate the wound area on limbs and torso of burn patients.

Assessing stapes piston position using computed tomography: a cadaveric study.

PubMed

Hahn, Yoav; Diaz, Rodney; Hartman, Jonathan; Bobinski, Matthew; Brodie, Hilary

2009-02-01

Temporal bone computed tomographic (CT) scanning in the postoperative stapedotomy patient is inaccurate in assessing stapes piston position within the vestibule. Poststapedotomy patients that have persistent vertigo may undergo CT scanning to assess the position of the stapes piston within the vestibule to rule out overly deep insertion. Vertigo is a recognized complication of the deep piston, and CT evaluation is often recommended. The accuracy of CT scan in this setting is unestablished. Stapedotomy was performed on 12 cadaver ears, and stainless steel McGee pistons were placed. The cadaver heads were then scanned using a fine-cut temporal bone protocol. Temporal bone dissection was performed with microscopic measurement of the piston depth in the vestibule. These values were compared with depth of intravestibular penetration measured on CT scan by 4 independent measurements. The intravestibular penetration as assessed by computed tomography was consistently greater than the value found on cadaveric anatomic dissection. The radiographic bias was greater when piston location within the vestibule was shallower. The axial CT scan measurement was 0.53 mm greater, on average, than the anatomic measurement. On average, the coronal CT measurement was 0.68 mm greater than the anatomic measurement. The degree of overestimation of penetration, however, was highly inconsistent. Standard temporal bone CT scan is neither an accurate nor precise examination of stapes piston depth within the vestibule. We found that CT measurement consistently overstated intravestibular piston depth. Computed tomography is not a useful study in the evaluation of piston depth for poststapedectomy vertigo and is of limited value in this setting.

Automated segmentation of intraretinal layers from macular optical coherence tomography images

NASA Astrophysics Data System (ADS)

Haeker, Mona; Sonka, Milan; Kardon, Randy; Shah, Vinay A.; Wu, Xiaodong; Abràmoff, Michael D.

2007-03-01

Commercially-available optical coherence tomography (OCT) systems (e.g., Stratus OCT-3) only segment and provide thickness measurements for the total retina on scans of the macula. Since each intraretinal layer may be affected differently by disease, it is desirable to quantify the properties of each layer separately. Thus, we have developed an automated segmentation approach for the separation of the retina on (anisotropic) 3-D macular OCT scans into five layers. Each macular series consisted of six linear radial scans centered at the fovea. Repeated series (up to six, when available) were acquired for each eye and were first registered and averaged together, resulting in a composite image for each angular location. The six surfaces defining the five layers were then found on each 3-D composite image series by transforming the segmentation task into that of finding a minimum-cost closed set in a geometric graph constructed from edge/regional information and a priori-determined surface smoothness and interaction constraints. The method was applied to the macular OCT scans of 12 patients with unilateral anterior ischemic optic neuropathy (corresponding to 24 3-D composite image series). The boundaries were independently defined by two human experts on one raw scan of each eye. Using the average of the experts' tracings as a reference standard resulted in an overall mean unsigned border positioning error of 6.7 +/- 4.0 μm, with five of the six surfaces showing significantly lower mean errors than those computed between the two observers (p < 0.05, pixel size of 50 × 2 μm).

Hearing loss associated with repeated MRI acquisition procedure-related acoustic noise exposure: an occupational cohort study.

PubMed

Bongers, Suzan; Slottje, Pauline; Kromhout, Hans

2017-11-01

To study the effects of repeated exposure to MRI-related acoustic noise during image acquisition procedures (scans) on hearing. A retrospective occupational cohort study was performed among workers of an MRI manufacturing facility (n=474). Longitudinal audiometry data from the facility's medical surveillance scheme collected from 1973 to 2010 were analysed by studying the association of cumulative exposure to MRI-related acoustic noise from voluntary (multiple) MRI scans and the hearing threshold of the volunteer. Repeated acoustic noise exposure during volunteer MRI scans was found to be associated with a small exposure-dependent increased rate change of hearing threshold level (dB/year), but the association was only found related to the number of voluntary MRI scans and not to modelled cumulative noise exposure (dB*hour) based on MRI-system type. The increased rate change of hearing threshold level was found to be statistically significant for the frequencies 500, 1000, 2000, 3000 and 4000 Hz in the right ear. From our longitudinal cohort study, it appeared that exposure to noise from voluntarily MRI scans may have resulted in a slight amount of hearing loss. Mandatory use of hearing protection might have prevented more severe hearing loss. Lack of consistency in findings between the left and right ears and between the two exposure measures prohibits definitive conclusions. Further research that addresses the study's methodological limitations is warranted to corroborate our findings. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Advanced Raman water vapor lidar

NASA Technical Reports Server (NTRS)

Whiteman, David N.; Melfi, S. Harvey; Ferrare, Richard A.; Evans, Keith A.; Ramos-Izquierdo, Luis; Staley, O. Glenn; Disilvestre, Raymond W.; Gorin, Inna; Kirks, Kenneth R.; Mamakos, William A.

1992-01-01

Water vapor and aerosols are important atmospheric constituents. Knowledge of the structure of water vapor is important in understanding convective development, atmospheric stability, the interaction of the atmosphere with the surface, and energy feedback mechanisms and how they relate to global warming calculations. The Raman Lidar group at the NASA Goddard Space Flight Center (GSFC) developed an advanced Raman Lidar for use in measuring water vapor and aerosols in the earth's atmosphere. Drawing on the experience gained through the development and use of our previous Nd:YAG based system, we have developed a completely new lidar system which uses a XeF excimer laser and a large scanning mirror. The additional power of the excimer and the considerably improved optical throughput of the system have resulted in approximately a factor of 25 improvement in system performance for nighttime measurements. Every component of the current system has new design concepts incorporated. The lidar system consists of two mobile trailers; the first (13m x 2.4m) houses the lidar instrument, the other (9.75m x 2.4m) is for system control, realtime data display, and analysis. The laser transmitter is a Lambda Physik LPX 240 iCC operating at 400 Hz with a XeF gas mixture (351 nm). The telescope is a .75m horizontally mounted Dall-Kirkham system which is bore sited with a .8m x 1.1m elliptical flat which has a full 180 degree scan capability - horizon to horizon within a plane perpendicular to the long axis of the trailer. The telescope and scan mirror assembly are mounted on a 3.65m x .9m optical table which deploys out the rear of the trailer through the use of a motor driven slide rail system. The Raman returns from water vapor (403 nm), nitrogen (383 nm) and oxygen (372 nm) are measured in addition to the direct Rayleigh/Mie backscatter (351). The signal from each of these is split at about a 5/95 ratio between two photomultiplier detectors. The 5 percent detector is used for measurements below about 4.0 km, while the 95 percent detector provides the information above this level.

Suitability of holographic beam scanning in high resolution applications

NASA Astrophysics Data System (ADS)

Kalita, Ranjan; Goutam Buddha, S. S.; Boruah, Bosanta R.

2018-02-01

The high resolution applications of a laser scanning imaging system very much demand the accurate positioning of the illumination beam. The galvanometer scanner based beam scanning imaging systems, on the other hand, suffer from both short term and long term beam instability issues. Fortunately Computer generated holography based beam scanning offers extremely accurate beam steering, which can be very useful for imaging in high-resolution applications in confocal microscopy. The holographic beam scanning can be achieved by writing a sequence of holograms onto a spatial light modulator and utilizing one of the diffracted orders as the illumination beam. This paper highlights relative advantages of such a holographic beam scanning based confocal system and presents some of preliminary experimental results.

Human abdomen recognition using camera and force sensor in medical robot system for automatic ultrasound scan.

PubMed

Bin Mustafa, Ammar Safwan; Ishii, Takashi; Matsunaga, Yoshiki; Nakadate, Ryu; Ishii, Hiroyuki; Ogawa, Kouji; Saito, Akiko; Sugawara, Motoaki; Niki, Kiyomi; Takanishi, Atsuo

2013-01-01

Physicians use ultrasound scans to obtain real-time images of internal organs, because such scans are safe and inexpensive. However, people in remote areas face difficulties to be scanned due to aging society and physician's shortage. Hence, it is important to develop an autonomous robotic system to perform remote ultrasound scans. Previously, we developed a robotic system for automatic ultrasound scan focusing on human's liver. In order to make it a completely autonomous system, we present in this paper a way to autonomously localize the epigastric region as the starting position for the automatic ultrasound scan. An image processing algorithm marks the umbilicus and mammary papillae on a digital photograph of the patient's abdomen. Then, we made estimation for the location of the epigastric region using the distances between these landmarks. A supporting algorithm distinguishes rib position from epigastrium using the relationship between force and displacement. We implemented these algorithms with the automatic scanning system into an apparatus: a Mitsubishi Electric's MELFA RV-1 six axis manipulator. Tests on 14 healthy male subjects showed the apparatus located the epigastric region with a success rate of 94%. The results suggest that image recognition was effective in localizing a human body part.

The Application of Lidar to Synthetic Vision System Integrity

NASA Technical Reports Server (NTRS)

Campbell, Jacob L.; UijtdeHaag, Maarten; Vadlamani, Ananth; Young, Steve

2003-01-01

One goal in the development of a Synthetic Vision System (SVS) is to create a system that can be certified by the Federal Aviation Administration (FAA) for use at various flight criticality levels. As part of NASA s Aviation Safety Program, Ohio University and NASA Langley have been involved in the research and development of real-time terrain database integrity monitors for SVS. Integrity monitors based on a consistency check with onboard sensors may be required if the inherent terrain database integrity is not sufficient for a particular operation. Sensors such as the radar altimeter and weather radar, which are available on most commercial aircraft, are currently being investigated for use in a real-time terrain database integrity monitor. This paper introduces the concept of using a Light Detection And Ranging (LiDAR) sensor as part of a real-time terrain database integrity monitor. A LiDAR system consists of a scanning laser ranger, an inertial measurement unit (IMU), and a Global Positioning System (GPS) receiver. Information from these three sensors can be combined to generate synthesized terrain models (profiles), which can then be compared to the stored SVS terrain model. This paper discusses an initial performance evaluation of the LiDAR-based terrain database integrity monitor using LiDAR data collected over Reno, Nevada. The paper will address the consistency checking mechanism and test statistic, sensitivity to position errors, and a comparison of the LiDAR-based integrity monitor to a radar altimeter-based integrity monitor.

Consistent integration of experimental and ab initio data into molecular and coarse-grained models

NASA Astrophysics Data System (ADS)

Vlcek, Lukas

As computer simulations are increasingly used to complement or replace experiments, highly accurate descriptions of physical systems at different time and length scales are required to achieve realistic predictions. The questions of how to objectively measure model quality in relation to reference experimental or ab initio data, and how to transition seamlessly between different levels of resolution are therefore of prime interest. To address these issues, we use the concept of statistical distance to define a measure of similarity between statistical mechanical systems, i.e., a model and its target, and show that its minimization leads to general convergence of the systems' measurable properties. Through systematic coarse-graining, we arrive at appropriate expressions for optimization loss functions consistently incorporating microscopic ab initio data as well as macroscopic experimental data. The design of coarse-grained and multiscale models is then based on factoring the model system partition function into terms describing the system at different resolution levels. The optimization algorithm takes advantage of thermodynamic perturbation expressions for fast exploration of the model parameter space, enabling us to scan millions of parameter combinations per hour on a single CPU. The robustness and generality of the new model optimization framework and its efficient implementation are illustrated on selected examples including aqueous solutions, magnetic systems, and metal alloys.

Multipurpose Hyperspectral Imaging System

NASA Technical Reports Server (NTRS)

Mao, Chengye; Smith, David; Lanoue, Mark A.; Poole, Gavin H.; Heitschmidt, Jerry; Martinez, Luis; Windham, William A.; Lawrence, Kurt C.; Park, Bosoon

2005-01-01

A hyperspectral imaging system of high spectral and spatial resolution that incorporates several innovative features has been developed to incorporate a focal plane scanner (U.S. Patent 6,166,373). This feature enables the system to be used for both airborne/spaceborne and laboratory hyperspectral imaging with or without relative movement of the imaging system, and it can be used to scan a target of any size as long as the target can be imaged at the focal plane; for example, automated inspection of food items and identification of single-celled organisms. The spectral resolution of this system is greater than that of prior terrestrial multispectral imaging systems. Moreover, unlike prior high-spectral resolution airborne and spaceborne hyperspectral imaging systems, this system does not rely on relative movement of the target and the imaging system to sweep an imaging line across a scene. This compact system (see figure) consists of a front objective mounted at a translation stage with a motorized actuator, and a line-slit imaging spectrograph mounted within a rotary assembly with a rear adaptor to a charged-coupled-device (CCD) camera. Push-broom scanning is carried out by the motorized actuator which can be controlled either manually by an operator or automatically by a computer to drive the line-slit across an image at a focal plane of the front objective. To reduce the cost, the system has been designed to integrate as many as possible off-the-shelf components including the CCD camera and spectrograph. The system has achieved high spectral and spatial resolutions by using a high-quality CCD camera, spectrograph, and front objective lens. Fixtures for attachment of the system to a microscope (U.S. Patent 6,495,818 B1) make it possible to acquire multispectral images of single cells and other microscopic objects.

Cerebral pyogranuloma associated with systemic coronavirus infection in a ferret.

PubMed

Gnirs, K; Quinton, J F; Dally, C; Nicolier, A; Ruel, Y

2016-01-01

A 2-year-old male ferret was presented with central nervous system signs. Computed tomography (CT) of the brain revealed a well-defined contrast-enhancing lesion on the rostral forebrain that appeared extraparenchymal. Surgical excision of the mass was performed and the ferret was euthanised during the procedure. Histopathology of the excised mass showed multiple meningeal nodular lesions with infiltrates of epithelioid macrophages, occasionally centred on degenerated neutrophils and surrounded by a broad rim of plasma cells, features consistent with pyogranulomatous meningitis. The histopathological features in this ferret were similar to those in cats with feline infectious peritonitis. Definitive diagnosis was assessed by immunohistochemistry, confirming a ferret systemic coronavirus (FSCV) associated disease. This is the first case of coronavirus granuloma described on CT-scan in the central nervous system of a ferret. © 2015 British Small Animal Veterinary Association.

Realtime photoacoustic microscopy in vivo with a 30-MHz ultrasound array transducer

PubMed Central

Zemp, Roger J.; Song, Liang; Bitton, Rachel; Shung, K. Kirk; Wang, Lihong V.

2009-01-01

We present a novel high-frequency photoacoustic microscopy system capable of imaging the microvasculature of living subjects in realtime to depths of a few mm. The system consists of a high-repetition-rate Q-switched pump laser, a tunable dye laser, a 30-MHz linear ultrasound array transducer, a multichannel high-frequency data acquisition system, and a shared-RAM multi-core-processor computer. Data acquisition, beamforming, scan conversion, and display are implemented in realtime at 50 frames per second. Clearly resolvable images of 6-µm-diameter carbon fibers are experimentally demonstrated at 80 µm separation distances. Realtime imaging performance is demonstrated on phantoms and in vivo with absorbing structures identified to depths of 2.5–3 mm. This work represents the first high-frequency realtime photoacoustic imaging system to our knowledge. PMID:18545502

Spacecraft Orbit Design and Analysis (SODA). Version 2.0: User's guide

NASA Technical Reports Server (NTRS)

Stallcup, Scott S.; Davis, John S.; Zsoldos, Jeffrey S.

1991-01-01

The Spacecraft Orbit Design and Analysis (SODA) computer program, Version 2.0, is discussed. SODA is a spaceflight mission planning system that consists of six program modules integrated around a common database and user interface. SODA runs on a VAX/VMS computer with an Evans and Sutherland PS300 graphics workstation. In the current version, three program modules produce an interactive three dimensional animation of one or more satellites in planetary orbit. Satellite visibility and sensor coverage capabilities are also provided. Circular and rectangular, off nadir, fixed and scanning sensors are supported. One module produces an interactive three dimensional animation of the solar system. Another module calculates cumulative satellite sensor coverage and revisit time for one or more satellites. Currently, Earth, Moon, and Mars systems are supported for all modules except the solar system module.

Postprocessing Algorithm for Driving Conventional Scanning Tunneling Microscope at Fast Scan Rates.

PubMed

Zhang, Hao; Li, Xianqi; Chen, Yunmei; Park, Jewook; Li, An-Ping; Zhang, X-G

2017-01-01

We present an image postprocessing framework for Scanning Tunneling Microscope (STM) to reduce the strong spurious oscillations and scan line noise at fast scan rates and preserve the features, allowing an order of magnitude increase in the scan rate without upgrading the hardware. The proposed method consists of two steps for large scale images and four steps for atomic scale images. For large scale images, we first apply for each line an image registration method to align the forward and backward scans of the same line. In the second step we apply a "rubber band" model which is solved by a novel Constrained Adaptive and Iterative Filtering Algorithm (CIAFA). The numerical results on measurement from copper(111) surface indicate the processed images are comparable in accuracy to data obtained with a slow scan rate, but are free of the scan drift error commonly seen in slow scan data. For atomic scale images, an additional first step to remove line-by-line strong background fluctuations and a fourth step of replacing the postprocessed image by its ranking map as the final atomic resolution image are required. The resulting image restores the lattice image that is nearly undetectable in the original fast scan data.

System of radiographic control or an imaging system for personal radiographic inspection

NASA Astrophysics Data System (ADS)

Babichev, E. A.; Baru, S. E.; Neustroev, V. A.; Leonov, V. V.; Porosev, V. V.; Savinov, G. A.; Ukraintsev, Yu. G.

2004-06-01

The security system of personal radiographic inspection for detection of explosive materials and plastic weapons was developed in BINP recently. Basic system parameters are: maximum scanning height— 2000 mm, image width— 800 mm, number of detector channels—768, channel size— 1.05×1 mm, charge collecting time for one line—2, 5 ms, scanning speed— 40 cm/s, maximum scanning time— 5 s, radiation dose per one inspection <5 μSv. The detector is a multichannel ionization Xe chamber. The image of inspected person will appear on the display just after scanning. The pilot sample of this system was put into operation in March, 2003.b

Developing Environmental Scanning/Forecasting Systems To Augment Community College Planning.

ERIC Educational Resources Information Center

Morrison, James L.; Held, William G.

A description is provided of a conference session that was conducted to explore the structure and function of an environmental scanning/forecasting system that could be used in a community college to facilitate planning. Introductory comments argue that a college that establishes an environmental scanning and forecasting system is able to identify…

Scanning System -- Technology Worth a Look

Treesearch

Philip A. Araman; Daniel L. Schmoldt; Richard W. Conners; D. Earl Kline

1995-01-01

In an effort to help automate the inspection for lumber defects, optical scanning systems are emerging as an alternative to the human eye. Although still in its infancy, scanning technology is being explored by machine companies and universities. This article was excerpted from "Machine Vision Systems for Grading and Processing Hardwood Lumber," by Philip...

Autoblocker: a system for detecting and blocking of network scanning based on analysis of netflow data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bobyshev, A.; Lamore, D.; Demar, P.

2004-12-01

In a large campus network, such at Fermilab, with tens of thousands of nodes, scanning initiated from either outside of or within the campus network raises security concerns. This scanning may have very serious impact on network performance, and even disrupt normal operation of many services. In this paper we introduce a system for detecting and automatic blocking excessive traffic of different kinds of scanning, DoS attacks, virus infected computers. The system, called AutoBlocker, is a distributed computing system based on quasi-real time analysis of network flow data collected from the border router and core switches. AutoBlocker also has anmore » interface to accept alerts from IDS systems (e.g. BRO, SNORT) that are based on other technologies. The system has multiple configurable alert levels for the detection of anomalous behavior and configurable trigger criteria for automated blocking of scans at the core or border routers. It has been in use at Fermilab for about 2 years, and has become a very valuable tool to curtail scan activity within the Fermilab campus network.« less

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PubMed

Harley, John B; Alarcón-Riquelme, Marta E; Criswell, Lindsey A; Jacob, Chaim O; Kimberly, Robert P; Moser, Kathy L; Tsao, Betty P; Vyse, Timothy J; Langefeld, Carl D; Nath, Swapan K; Guthridge, Joel M; Cobb, Beth L; Mirel, Daniel B; Marion, Miranda C; Williams, Adrienne H; Divers, Jasmin; Wang, Wei; Frank, Summer G; Namjou, Bahram; Gabriel, Stacey B; Lee, Annette T; Gregersen, Peter K; Behrens, Timothy W; Taylor, Kimberly E; Fernando, Michelle; Zidovetzki, Raphael; Gaffney, Patrick M; Edberg, Jeffrey C; Rioux, John D; Ojwang, Joshua O; James, Judith A; Merrill, Joan T; Gilkeson, Gary S; Seldin, Michael F; Yin, Hong; Baechler, Emily C; Li, Quan-Zhen; Wakeland, Edward K; Bruner, Gail R; Kaufman, Kenneth M; Kelly, Jennifer A

2008-02-01

Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex etiology but strong clustering in families (lambda(S) = approximately 30). We performed a genome-wide association scan using 317,501 SNPs in 720 women of European ancestry with SLE and in 2,337 controls, and we genotyped consistently associated SNPs in two additional independent sample sets totaling 1,846 affected women and 1,825 controls. Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269). We also found evidence for association (P < 1 x 10(-5)) at FCGR2A, PTPN22 and STAT4, regions previously associated with SLE and other autoimmune diseases, as well as at > or =9 other loci (P < 2 x 10(-7)). Our results show that numerous genes, some with known immune-related functions, predispose to SLE.

Health care using high-bandwidth communication to overcome distance and time barriers for the Department of Defense

NASA Astrophysics Data System (ADS)

Mun, Seong K.; Freedman, Matthew T.; Gelish, Anthony; de Treville, Robert E.; Sheehy, Monet R.; Hansen, Mark; Hill, Mac; Zacharia, Elisabeth; Sullivan, Michael J.; Sebera, C. Wayne

1993-01-01

Image management and communications (IMAC) network, also known as picture archiving and communication system (PACS) consists of (1) digital image acquisition, (2) image review station (3) image storage device(s), image reading workstation, and (4) communication capability. When these subsystems are integrated over a high speed communication technology, possibilities are numerous in improving the timeliness and quality of diagnostic services within a hospital or at remote clinical sites. Teleradiology system uses basically the same hardware configuration together with a long distance communication capability. Functional characteristics of components are highlighted. Many medical imaging systems are already in digital form. These digital images constitute approximately 30% of the total volume of images produced in a radiology department. The remaining 70% of images include conventional x-ray films of the chest, skeleton, abdomen, and GI tract. Unless one develops a method of handling these conventional film images, global improvement in productivity in image management and radiology service throughout a hospital cannot be achieved. Currently, there are two method of producing digital information representing these conventional analog images for IMAC: film digitizers that scan the conventional films, and computed radiography (CR) that captures x-ray images using storage phosphor plate that is subsequently scanned by a laser beam.

Optics detection and laser countermeasures on a combat vehicle

NASA Astrophysics Data System (ADS)

Sjöqvist, Lars; Allard, Lars; Pettersson, Magnus; Börjesson, Per; Lindskog, Nils; Bodin, Johan; Widén, Anders; Persson, Hâkan; Fredriksson, Jan; Edström, Sten

2016-10-01

Magnifying optical assemblies used for weapon guidance or rifle scopes may possess a threat for a combat vehicle and its personnel. Detection and localisation of optical threats is consequently of interest in military applications. Typically a laser system is used in optics detection, or optical augmentation, to interrogate a scene of interest to localise retroreflected laser radiation. One interesting approach for implementing optics detection on a combat vehicle is to use a continuous scanning scheme. In addition, optics detection can be combined with laser countermeasures, or a laser dazzling function, to efficiently counter an optical threat. An optics detection laser sensor demonstrator has been implemented on a combat vehicle. The sensor consists of a stabilised gimbal and was integrated together with a LEMUR remote electro-optical sight. A narrow laser slit is continuously scanned around the horizon to detect and locate optical threats. Detected threats are presented for the operator within the LEMUR presentation system, and by cueing a countermeasure laser installed in the LEMUR sensor housing threats can be defeated. Results obtained during a field demonstration of the optics detection sensor and the countermeasure laser will be presented. In addition, results obtained using a dual-channel optics detection system designed for false alarm reduction are also discussed.

Light Detection and Ranging-Based Terrain Navigation: A Concept Exploration

NASA Technical Reports Server (NTRS)

Campbell, Jacob; UijtdeHaag, Maarten; vanGraas, Frank; Young, Steve

2003-01-01

This paper discusses the use of Airborne Light Detection And Ranging (LiDAR) equipment for terrain navigation. Airborne LiDAR is a relatively new technology used primarily by the geo-spatial mapping community to produce highly accurate and dense terrain elevation maps. In this paper, the term LiDAR refers to a scanning laser ranger rigidly mounted to an aircraft, as opposed to an integrated sensor system that consists of a scanning laser ranger integrated with Global Positioning System (GPS) and Inertial Measurement Unit (IMU) data. Data from the laser range scanner and IMU will be integrated with a terrain database to estimate the aircraft position and data from the laser range scanner will be integrated with GPS to estimate the aircraft attitude. LiDAR data was collected using NASA Dryden's DC-8 flying laboratory in Reno, NV and was used to test the proposed terrain navigation system. The results of LiDAR-based terrain navigation shown in this paper indicate that airborne LiDAR is a viable technology enabler for fully autonomous aircraft navigation. The navigation performance is highly dependent on the quality of the terrain databases used for positioning and therefore high-resolution (2 m post-spacing) data was used as the terrain reference.

Derivation of the scan time requirement for maintaining a consistent PET image quality

NASA Astrophysics Data System (ADS)

Kim, Jin Su; Lee, Jae Sung; Kim, Seok-Ki

2015-05-01

Objectives: the image quality of PET for larger patients is relatively poor, even though the injection dose is optimized considering the NECR characteristics of the PET scanner. This poor image quality is due to the lower level of maximum NECR that can be achieved in these large patients. The aim of this study was to optimize the PET scan time to obtain a consistent PET image quality regardless of the body size, based on the relationship between the patient specific NECR (pNECR) and body weight. Methods: eighty patients (M/F=53/27, body weight: 059 ± 1 kg) underwent whole-body FDG PET scans using a Philips GEMINI GS PET/CT scanner after an injection of 0.14 mCi/kg FDG. The relationship between the scatter fraction (SF) and body weight was determined by repeated Monte Carlo simulations using a NEMA scatter phantom, the size of which varied according to the relationship between the abdominal circumference and body weight. Using this information, the pNECR was calculated from the prompt and delayed PET sinograms to obtain the prediction equation of NECR vs. body weight. The time scaling factor (FTS) for the scan duration was finally derived to make PET images with equivalent SNR levels. Results: the SF and NECR had the following nonlinear relationships with the body weight: SF=0.15 ṡ body weight0.3 and NECR = 421.36 (body weight)-0.84. The equation derived for FTS was 0.01ṡ body weight + 0.2, which means that, for example, a 120-kg person should be scanned 1.8 times longer than a 70 kg person, or the scan time for a 40-kg person can be reduced by 30%. Conclusion: the equation of the relative time demand derived in this study will be useful for maintaining consistent PET image quality in clinics.

Functional brain MRI in patients complaining of electrohypersensitivity after long term exposure to electromagnetic fields.

PubMed

Heuser, Gunnar; Heuser, Sylvia A

2017-09-26

Ten adult patients with electromagnetic hypersensitivity underwent functional magnetic resonance imaging (fMRI) brain scans. All scans were abnormal with abnormalities which were consistent and similar. It is proposed that fMRI brain scans be used as a diagnostic aid for determining whether or not a patient has electromagnetic hypersensitivity. Over the years we have seen an increasing number of patients who had developed multi system complaints after long term repeated exposure to electromagnetic fields (EMFs). These complaints included headaches, intermittent cognitive and memory problems, intermittent disorientation, and also sensitivity to EMF exposure. Regular laboratory tests were within normal limits in these patients. The patients refused to be exposed to radioactivity. This of course ruled out positron emission tomography (PET) and single-photon emission computed tomography (SPECT) brain scanning. This is why we ordered fMRI brain scans on these patients. We hoped that we could document objective abnormalities in these patients who had often been labeled as psychiatric cases. Ten patients first underwent a regular magnetic resonance imaging (MRI) brain scan, using a 3 Tesla Siemens Verio MRI open system. A functional MRI study was then performed in the resting state using the following sequences: A three-dimensional, T1-weighted, gradient-echo (MPRAGE) Resting state network. The echo-planar imaging (EPI) sequences for this resting state blood oxygenation level dependent (BOLD) scan were then post processed on a 3D workstation and the independent component analysis was performed separating out the various networks. Arterial spin labeling. Tractography and fractional anisotropy. All ten patients had abnormal functional MRI brain scans. The abnormality was often described as hyper connectivity of the anterior component of the default mode in the medial orbitofrontal area. Other abnormalities were usually found. Regular MRI studies of the brain were mostly unremarkable in these patients. We propose that functional MRI studies should become a diagnostic aid when evaluating a patient who claims electrohypersensitivity (EHS) and has otherwise normal studies. Interestingly, the differential diagnosis for the abnormalities seen on the fMRI includes head injury. It turns out that many of our patients indeed had a history of head injury which was then followed sometime later by the development of EHS. Many of our patients also had a history of exposure to potentially neurotoxic chemicals, especially mold. Head injury and neurotoxic chemical exposure may make a patient more vulnerable to develop EHS.

Out of lab calibration of a rotating 2D scanner for 3D mapping

NASA Astrophysics Data System (ADS)

Koch, Rainer; Böttcher, Lena; Jahrsdörfer, Maximilian; Maier, Johannes; Trommer, Malte; May, Stefan; Nüchter, Andreas

2017-06-01

Mapping is an essential task in mobile robotics. To fulfil advanced navigation and manipulation tasks a 3D representation of the environment is required. Applying stereo cameras or Time-of-flight cameras (TOF cameras) are one way to archive this requirement. Unfortunately, they suffer from drawbacks which makes it difficult to map properly. Therefore, costly 3D laser scanners are applied. An inexpensive way to build a 3D representation is to use a 2D laser scanner and rotate the scan plane around an additional axis. A 3D point cloud acquired with such a custom device consists of multiple 2D line scans. Therefore the scanner pose of each line scan need to be determined as well as parameters resulting from a calibration to generate a 3D point cloud. Using external sensor systems are a common method to determine these calibration parameters. This is costly and difficult when the robot needs to be calibrated outside the lab. Thus, this work presents a calibration method applied on a rotating 2D laser scanner. It uses a hardware setup to identify the required parameters for calibration. This hardware setup is light, small, and easy to transport. Hence, an out of lab calibration is possible. Additional a theoretical model was created to test the algorithm and analyse impact of the scanner accuracy. The hardware components of the 3D scanner system are an HOKUYO UTM-30LX-EW 2D laser scanner, a Dynamixel servo-motor, and a control unit. The calibration system consists of an hemisphere. In the inner of the hemisphere a circular plate is mounted. The algorithm needs to be provided with a dataset of a single rotation from the laser scanner. To achieve a proper calibration result the scanner needs to be located in the middle of the hemisphere. By means of geometric formulas the algorithms determine the individual deviations of the placed laser scanner. In order to minimize errors, the algorithm solves the formulas in an iterative process. First, the calibration algorithm was tested with an ideal hemisphere model created in Matlab. Second, laser scanner was mounted differently, the scanner position and the rotation axis was modified. In doing so, every deviation, was compared with the algorithm results. Several measurement settings were tested repeatedly with the 3D scanner system and the calibration system. The results show that the length accuracy of the laser scanner is most critical. It influences the required size of the hemisphere and the calibration accuracy.

Validity and reliability of a structured-light 3D scanner and an ultrasound imaging system for measurements of facial skin thickness.

PubMed

Lee, Kang-Woo; Kim, Sang-Hwan; Gil, Young-Chun; Hu, Kyung-Seok; Kim, Hee-Jin

2017-10-01

Three-dimensional (3 D)-scanning-based morphological studies of the face are commonly included in various clinical procedures. This study evaluated validity and reliability of a 3 D scanning system by comparing the ultrasound (US) imaging system versus the direct measurement of facial skin. The facial skin thickness at 19 landmarks was measured using the three different methods in 10 embalmed adult Korean cadavers. Skin thickness was first measured using the ultrasound device, then 3 D scanning of the facial skin surface was performed. After the skin on the left half of face was gently dissected, deviating slightly right of the midline, to separate it from the subcutaneous layer, and the harvested facial skin's thickness was measured directly using neck calipers. The dissected specimen was then scanned again, then the scanned images of undissected and dissected faces were superimposed using Morpheus Plastic Solution (version 3.0) software. Finally, the facial skin thickness was calculated from the superimposed images. The ICC value for the correlations between the 3 D scanning system and direct measurement showed excellent reliability (0.849, 95% confidence interval = 0.799-0.887). Bland-Altman analysis showed a good level of agreement between the 3 D scanning system and direct measurement (bias = 0.49 ± 0.49 mm, mean±SD). These results demonstrate that the 3 D scanning system precisely reflects structural changes before and after skin dissection. Therefore, an in-depth morphological study using this 3 D scanning system could provide depth data about the main anatomical structures of face, thereby providing crucial anatomical knowledge for utilization in various clinical applications. Clin. Anat. 30:878-886, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Calibration of the Verification Engineering Test Article-I (VETA-I) for AXAF using the VETA-I X-ray Detection System

NASA Technical Reports Server (NTRS)

Kellogg, E.; Brissenden, R.; Flanagan, K.; Freeman, M.; Hughes, J.; Jones, M.; Ljungberg, M.; Mckinnon, P.; Podgorski, W.; Schwartz, D.

1992-01-01

Advanced X-ray Astrophysics Facility (AXAF) X-ray optics testing is conducted by VETA-I, which consists of six nested Wolter type I grazing-incidence mirrors; VETA's X-ray Detection System (VXDS) in turn measures the imaging properties of VETA-I, yielding FWHM and encircled energy of the X-ray image obtained, as well as its effective area. VXDS contains a high resolution microchannel plate imaging X-ray detector and a pinhole scanning system in front of proportional-counter detectors. VETA-I's X-ray optics departs from the AXAF flight configuration in that it uses a temporary holding fixture; its mirror elements are not cut to final length, and are not coated with the metal film used to maximize high-energy reflection.

Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses.

PubMed

Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús; Rosete-Aguilar, Martha; Román-Moreno, Carlos J

2015-08-01

In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low power consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.

Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses

NASA Astrophysics Data System (ADS)

Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús; Rosete-Aguilar, Martha; Román-Moreno, Carlos J.

2015-08-01

In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low power consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.

The LSLE echocardiograph - Commercial hardware aboard Spacelab. [Life Sciences Laboratory Equipment

NASA Technical Reports Server (NTRS)

Schwarz, R.

1983-01-01

The Life Sciences Laboratory Equipment Echocardiograph, a commercial 77020AC Ultrasound Imaging System modified to meet NASA's spacecraft standards, is described. The assembly consists of four models: display and control, scanner, scan converter, and physioamplifiers. Four separate processors communicate over an IEE-488 bus, and the system has more than 6000 individual components on 35 printed circuit cards. Three levels of self test are provided: a short test during power up, a basic test initiated by a front panel switch, and interactive tests for specific routines. Default mode operation further enhances reliability. Modifications of the original system include the replacement of ac power supplies with dc to dc converters, a slide-out keyboard (to prevent accidental operation), Teflon insulated wire, and additional shielding for the ultrasound transducer cable.

SU-E-T-118: Analysis of Variability and Stability Between Two Water Tank Phantoms Utilizing Water Tank Commissioning Procedures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roring, J; Saenz, D; Cruz, W

2015-06-15

Purpose: The commissioning criteria of water tank phantoms are essential for proper accuracy and reproducibility in a clinical setting. This study outlines the results of mechanical and dosimetric testing between PTW MP3-M water tank system and the Standard Imaging Doseview 3D water tank system. Methods: Measurements were taken of each axis of movement on the tank using 30 cm calipers at 1, 5, 10, 50, 100, and 200 mm for accuracy and reproducibility of tank movement. Dosimetric quantities such as percent depth dose and dose profiles were compared between tanks using a 6 MV beam from a Varian 23EX LINAC.more » Properties such as scanning speed effects, central axis depth dose agreement with static measurements, reproducibility of measurements, symmetry and flatness, and scan time between tanks were also investigated. Results: Results showed high geometric accuracy within 0.2 mm. Central axis PDD and in-field profiles agreed within 0.75% between the tanks. These outcomes test many possible discrepancies in dose measurements across the two tanks and form a basis for comparison on a broader range of tanks in the future. Conclusion: Both 3D water scanning phantoms possess a high degree of spatial accuracy, allowing for equivalence in measurements regardless of the phantom used. A commissioning procedure when changing water tanks or upon receipt of a new tank is nevertheless critical to ensure consistent operation before and after the arrival of new hardware.« less

Module generation for self-testing integrated systems

NASA Astrophysics Data System (ADS)

Vanriessen, Ronald Pieter

Hardware used for self test in VLSI (Very Large Scale Integrated) systems is reviewed, and an architecture to control the test hardware in an integrated system is presented. Because of the increase of test times, the use of self test techniques has become practically and economically viable for VLSI systems. Beside the reduction in test times and costs, self test also provides testing at operational speeds. Therefore, a suitable combination of scan path and macrospecific (self) tests is required to reduce test times and costs. An expert system that can be used in a silicon compilation environment is presented. The approach requires a minimum of testability knowledge from a system designer. A user friendly interface was described for specifying and modifying testability requirements by a testability expert. A reason directed backtracking mechanism is used to solve selection failures. Both the hierarchical testable architecture and the design for testability expert system are used in a self test compiler. The definition of a self test compiler was given. A self test compiler is a software tool that selects an appropriate test method for every macro in a design. The hardware to control a macro test will be included in the design automatically. As an example, the integration of the self-test compiler in a silicon compilation system PIRAMID was described. The design of a demonstrator circuit by self test compiler is described. This circuit consists of two self testable macros. Control of the self test hardware is carried out via the test access port of the boundary scan standard.

Studies of Atmospheric Water in Storms with the Nimbus 7 Scanning Multichannel Microwave Radiometer

NASA Technical Reports Server (NTRS)

Katsaros, K. B.

1984-01-01

The new tools for the study of midlattitude cyclones by atmospheric water channels of the scanning multichannel microwave radiometer (SMMR) on Nimbus 7, were discussed. The integrated atmospheric water vapor, total cloud liquid water and rain data were obtained from the Nimbus 7 Scanning Multichannel Microwave Radiometer (SMMR). The frontal structure of several midlattitude cyclones over the North Pacific Ocean as they approached the West Coast of North America were studied. It is found that fronts are consistently located at the leading edge of the strongest gradient in integrated water vapor. The cloud liquid water content has patterns which are consistent with the structure seen in visible and infrared imagery. The rain distribution is a good indicator of frontal location. It is concluded that the onset of rain on the coast can be forecast accurately by simple advection of the SMMR observed rain areas.

High-speed polarization sensitive optical coherence tomography for retinal diagnostics

NASA Astrophysics Data System (ADS)

Yin, Biwei; Wang, Bingqing; Vemishetty, Kalyanramu; Nagle, Jim; Liu, Shuang; Wang, Tianyi; Rylander, Henry G., III; Milner, Thomas E.

2012-01-01

We report design and construction of an FPGA-based high-speed swept-source polarization-sensitive optical coherence tomography (SS-PS-OCT) system for clinical retinal imaging. Clinical application of the SS-PS-OCT system is accurate measurement and display of thickness, phase retardation and birefringence maps of the retinal nerve fiber layer (RNFL) in human subjects for early detection of glaucoma. The FPGA-based SS-PS-OCT system provides three incident polarization states on the eye and uses a bulk-optic polarization sensitive balanced detection module to record two orthogonal interference fringe signals. Interference fringe signals and relative phase retardation between two orthogonal polarization states are used to obtain Stokes vectors of light returning from each RNFL depth. We implement a Levenberg-Marquardt algorithm on a Field Programmable Gate Array (FPGA) to compute accurate phase retardation and birefringence maps. For each retinal scan, a three-state Levenberg-Marquardt nonlinear algorithm is applied to 360 clusters each consisting of 100 A-scans to determine accurate maps of phase retardation and birefringence in less than 1 second after patient measurement allowing real-time clinical imaging-a speedup of more than 300 times over previous implementations. We report application of the FPGA-based SS-PS-OCT system for real-time clinical imaging of patients enrolled in a clinical study at the Eye Institute of Austin and Duke Eye Center.

Development of a Vitality Scan related to workers' sustainable employability: a study assessing its internal consistency and construct validity.

PubMed

Brouwers, Livia A M; Engels, Josephine A; Heerkens, Yvonne F; van der Beek, Allard J

2015-06-16

Most validated sustainable employability questionnaires are extensive and difficult to obtain. Our objective was to develop a usable and valid tool, a Vitality Scan, to determine possible signs of stagnation in one's functioning related to sustainable employability and to establish the instrument's internal consistency and construct validity. A literature review was performed and expert input was obtained to develop an online survey of 31 items. A sample of 1722 Dutch employees was recruited. Internal consistency was assessed by Cronbach's alpha. The underlying theoretical concepts were extracted by factor analysis using a principal component method. For construct validity, a priori hypotheses were defined for expected differences between known subgroups: 1) older workers would report more stagnation than younger workers, and 2) less educated workers would report more problems than the highly educated ones. Both hypotheses were statistically tested using ANOVA. Internal consistency measures and factor analysis resulted in five subscales with acceptable to good reliability (Cronbach's alpha 0.72-0.87). These subscales included: balance and competence, motivation and involvement, resilience, mental and physical health, and social support at work. Three items were removed following these analyses. In accordance with our a priori hypothesis 1, the ANOVA showed that older workers reported the most problems, while younger workers reported the least problems. However, hypothesis 2 was not confirmed: no significant differences were found for education level. The developed Vitality Scan - with the 28 remaining items - showed good measurement properties. It is applicable as a user-friendly, evaluative instrument for worker's sustainable employability. The scan's value for determining whether or not the employee is at risk for a decrease in functioning during present and future work, should be further tested.

Quantitative Thin-Layer Chromatography/Mass Spectrometry Analysis of Caffeine Using a Surface Sampling Probe Electrospray Ionization Tandem Mass Spectrometry System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ford, Michael J; Deibel, Michael A.; Tomkins, Bruce A

Quantitative determination of caffeine on reversed-phase C8 thin-layer chromatography plates using a surface sampling electrospray ionization system with tandem mass spectrometry detection is reported. The thin-layer chromatography/electrospray tandem mass spectrometry method employed a deuterium-labeled caffeine internal standard and selected reaction monitoring detection. Up to nine parallel caffeine bands on a single plate were sampled in a single surface scanning experiment requiring 35 min at a surface scan rate of 44 {mu}m/s. A reversed-phase HPLC/UV caffeine assay was developed in parallel to assess the mass spectrometry method performance. Limits of detection for the HPLC/UV and thin-layer chromatography/electrospray tandem mass spectrometry methodsmore » determined from the calibration curve statistics were 0.20 ng injected (0.50 {mu}L) and 1.0 ng spotted on the plate, respectively. Spike recoveries with standards and real samples ranged between 97 and 106% for both methods. The caffeine content of three diet soft drinks (Diet Coke, Diet Cherry Coke, Diet Pepsi) and three diet sport drinks (Diet Turbo Tea, Speed Stack Grape, Speed Stack Fruit Punch) was measured. The HPLC/UV and mass spectrometry determinations were in general agreement, and these values were consistent with the quoted values for two of the three diet colas. In the case of Diet Cherry Coke and the diet sports drinks, the determined caffeine amounts using both methods were consistently higher (by 8% or more) than the literature values.« less

Evaluation of the propulsion control system of a planetary rover and design of a mast for an elevation scanning laser/multi-detector system

NASA Technical Reports Server (NTRS)

Knaub, D.; Yerazunis, S. W.

1978-01-01

Vertical wheel loads, wheel speeds, and torque relationships are considered in the design of a propulsion system capable of responding to steering, slope climbing, and irregular local terrains. The system developed is applied to the RPI Mars roving vehicle. The mechanical system required to implement the elevation laser scanning/multidetector principle was the design and construction of a mechanical system for implementing the elevation scanning/multidetector principle is also discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wulfmeyer, Volker; Turner, David

The Land-Atmosphere Feedback Experiment (LAFE; pronounced “la-fey”) deploys several state-of-the-art scanning lidar and remote sensing systems to the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility’s Southern Great Plains (SGP) site. These instruments will augment the ARM instrument suite in order to collect a data set for studying feedback processes between the land surface and the atmosphere. The novel synergy of remote-sensing systems will be applied for simultaneous measurements of land-surface fluxes and horizontal and vertical transport processes in the atmospheric convective boundary layer (CBL). The impact of spatial inhomogeneities of the soil-vegetation continuum on land-surface-atmospheremore » (LSA) feedback will be studied using the scanning capability of the instrumentation. The time period of the observations is August 2017, because large differences in surface fluxes between different fields and bare soil can be observed, e.g., pastures versus fields where the wheat has already been harvested. The remote sensing system synergy will consist of three components: 1) The SGP water vapor and temperature Raman lidar (SRL), the SGP Doppler lidar (SDL), and the National Center for Atmospheric Research (NCAR) water vapor differential absorption lidar (DIAL) (NDIAL) mainly in vertical staring modes to measure mean profiles and gradients of moisture, temperature, and horizontal wind. They will also measure profiles of higher-order turbulent moments in the water vapor and wind fields and profiles of the latent heat flux. 2) A novel scanning lidar system synergy consisting of the National Oceanic and Atmospheric Administration (NOAA) High-Resolution Doppler lidar (HRDL), the University of Hohenheim (UHOH) water-vapor differential absorption lidar (UDIAL), and the UHOH temperature Raman lidar (URL). These systems will perform coordinated range-height indicator (RHI) scans from just above the canopy level to the lower troposphere, including the interfacial layer of the CBL. The optimal azimuth is to the ENE of the SGP central facility, which takes advantage of both changes in the surface elevation and different crop types planted along that path. 3) The University of Wisconsin Space Science and Engineering Center Portable Atmospheric Research Center (SPARC) and the University of Oklahoma Collaborative Lower Atmospheric Mobile Profiling System (CLAMPS) operating two vertically pointing atmospheric emitted radiance interferometers (AERIs) and two Doppler lidar (DL) systems scanning cross track to the central RHI for determining the surface friction velocity and the horizontal variability of temperature, moisture, and wind. Thus, both the variability of surface fluxes and CBL dynamics and thermodynamics over the SGP site will be studied for the first time. The combination of these three components will enable us to estimate both the divergence of the latent heat profile and the advection of moisture. Thus, the moisture budget in the SGP domain can be studied. Furthermore, the simultaneous measurements of surface and entrainment fluxes as well as the daily cycle of the CBL thermodynamic state will provide a unique data set for characterizing LSA interaction in dependence of large-scale and local conditions such as soil moisture and the state of the vegetation. The measurements will also be applied for the development of improved parameterizations of surface fluxes and turbulence in the CBL. The latter is possible because mean profiles, gradients, higher-order moments, and fluxes are measured simultaneously. The results will be used for the verification of simulations of LSA feedback in large-eddy simulation (LES) and mesoscale models, which are planned for the SGP site. Due to the strong connection between the pre-convective state of the CBL and the formation of clouds and precipitation, this new generation of experiments will strongly contribute to the improvement of their representation in weather, climate, and earth system models.« less

A versatile nondestructive evaluation imaging workstation

NASA Technical Reports Server (NTRS)

Chern, E. James; Butler, David W.

1994-01-01

Ultrasonic C-scan and eddy current imaging systems are of the pointwise type evaluation systems that rely on a mechanical scanner to physically maneuver a probe relative to the specimen point by point in order to acquire data and generate images. Since the ultrasonic C-scan and eddy current imaging systems are based on the same mechanical scanning mechanisms, the two systems can be combined using the same PC platform with a common mechanical manipulation subsystem and integrated data acquisition software. Based on this concept, we have developed an IBM PC-based combined ultrasonic C-scan and eddy current imaging system. The system is modularized and provides capacity for future hardware and software expansions. Advantages associated with the combined system are: (1) eliminated duplication of the computer and mechanical hardware, (2) unified data acquisition, processing and storage software, (3) reduced setup time for repetitious ultrasonic and eddy current scans, and (4) improved system efficiency. The concept can be adapted to many engineering systems by integrating related PC-based instruments into one multipurpose workstation such as dispensing, machining, packaging, sorting, and other industrial applications.

A versatile nondestructive evaluation imaging workstation

NASA Astrophysics Data System (ADS)

Chern, E. James; Butler, David W.

1994-02-01

Ultrasonic C-scan and eddy current imaging systems are of the pointwise type evaluation systems that rely on a mechanical scanner to physically maneuver a probe relative to the specimen point by point in order to acquire data and generate images. Since the ultrasonic C-scan and eddy current imaging systems are based on the same mechanical scanning mechanisms, the two systems can be combined using the same PC platform with a common mechanical manipulation subsystem and integrated data acquisition software. Based on this concept, we have developed an IBM PC-based combined ultrasonic C-scan and eddy current imaging system. The system is modularized and provides capacity for future hardware and software expansions. Advantages associated with the combined system are: (1) eliminated duplication of the computer and mechanical hardware, (2) unified data acquisition, processing and storage software, (3) reduced setup time for repetitious ultrasonic and eddy current scans, and (4) improved system efficiency. The concept can be adapted to many engineering systems by integrating related PC-based instruments into one multipurpose workstation such as dispensing, machining, packaging, sorting, and other industrial applications.

PSIDD (2): A Prototype Post-Scan Interactive Data Display System for Detailed Analysis of Ultrasonic Scans

NASA Technical Reports Server (NTRS)

Cao, Wei; Roth, Don J.

1997-01-01

This article presents the description of PSIDD(2), a post-scan interactive data display system for ultrasonic contact scan and single measurement analysis. PSIDD(2) was developed in conjunction with ASTM standards for ultrasonic velocity and attenuation coefficient contact measurements. This system has been upgraded from its original version PSIDD(1) and improvements are described in this article. PSIDD(2) implements a comparison mode where the display of time domain waveforms and ultrasonic properties versus frequency can be shown for up to five scan points on one plot. This allows the rapid contrasting of sample areas exhibiting different ultrasonic properties as initially indicated by the ultrasonic contact scan image. This improvement plus additional features to be described in the article greatly facilitate material microstructural appraisal.

Design and verification of the miniature optical system for small object surface profile fast scanning

NASA Astrophysics Data System (ADS)

Chi, Sheng; Lee, Shu-Sheng; Huang, Jen, Jen-Yu; Lai, Ti-Yu; Jan, Chia-Ming; Hu, Po-Chi

2016-04-01

As the progress of optical technologies, different commercial 3D surface contour scanners are on the market nowadays. Most of them are used for reconstructing the surface profile of mold or mechanical objects which are larger than 50 mm×50 mm× 50 mm, and the scanning system size is about 300 mm×300 mm×100 mm. There are seldom optical systems commercialized for surface profile fast scanning for small object size less than 10 mm×10 mm×10 mm. Therefore, a miniature optical system has been designed and developed in this research work for this purpose. Since the most used scanning method of such system is line scan technology, we have developed pseudo-phase shifting digital projection technology by adopting projecting fringes and phase reconstruction method. A projector was used to project a digital fringe patterns on the object, and the fringes intensity images of the reference plane and of the sample object were recorded by a CMOS camera. The phase difference between the plane and object can be calculated from the fringes images, and the surface profile of the object was reconstructed by using the phase differences. The traditional phase shifting method was accomplished by using PZT actuator or precisely controlled motor to adjust the light source or grating and this is one of the limitations for high speed scanning. Compared with the traditional optical setup, we utilized a micro projector to project the digital fringe patterns on the sample. This diminished the phase shifting processing time and the controlled phase differences between the shifted phases become more precise. Besides, the optical path design based on a portable device scanning system was used to minimize the size and reduce the number of the system components. A screwdriver section about 7mm×5mm×5mm has been scanned and its surface profile was successfully restored. The experimental results showed that the measurement area of our system can be smaller than 10mm×10mm, the precision reached to +/-10μm, and the scanning time for each surface of an object was less than 15 seconds. This has proved that our system own the potential to be a fast scanning scanner for small object surface profile scanning.

STEM VQ Method, Using Scanning Transmission Electron Microscopy (STEM) for Accurate Virus Quantification

DTIC Science & Technology

2017-02-02

Corresponding Author Abstract Accurate virus quantification is sought, but a perfect method still eludes the scientific community. Electron...unlimited. UNCLASSIFIED 2 provides morphology data and counts all viral particles, including partial or noninfectious particles; however, EM methods ...consistent, reproducible virus quantification method called Scanning Transmission Electron Microscopy – Virus Quantification (STEM-VQ) which simplifies

Proposing a Center on Aging and Well-Being: Research, Education, and Practice Considerations

ERIC Educational Resources Information Center

Lindenbach, Jeannette M.; Jessup-Falcioni, Heather

2016-01-01

This environmental scan aimed to discover research interests and educational needs of faculty, graduate, and undergraduate students to inspire research, education, and practice in the development of a center on aging and well-being for older adults. The scan consisted of a search of university faculty and researchers regarding research on aging; a…

Haptic computer-assisted patient-specific preoperative planning for orthopedic fractures surgery.

PubMed

Kovler, I; Joskowicz, L; Weil, Y A; Khoury, A; Kronman, A; Mosheiff, R; Liebergall, M; Salavarrieta, J

2015-10-01

The aim of orthopedic trauma surgery is to restore the anatomy and function of displaced bone fragments to support osteosynthesis. For complex cases, including pelvic bone and multi-fragment femoral neck and distal radius fractures, preoperative planning with a CT scan is indicated. The planning consists of (1) fracture reduction-determining the locations and anatomical sites of origin of the fractured bone fragments and (2) fracture fixation-selecting and placing fixation screws and plates. The current bone fragment manipulation, hardware selection, and positioning processes based on 2D slices and a computer mouse are time-consuming and require a technician. We present a novel 3D haptic-based system for patient-specific preoperative planning of orthopedic fracture surgery based on CT scans. The system provides the surgeon with an interactive, intuitive, and comprehensive, planning tool that supports fracture reduction and fixation. Its unique features include: (1) two-hand haptic manipulation of 3D bone fragments and fixation hardware models; (2) 3D stereoscopic visualization and multiple viewing modes; (3) ligaments and pivot motion constraints to facilitate fracture reduction; (4) semiautomatic and automatic fracture reduction modes; and (5) interactive custom fixation plate creation to fit the bone morphology. We evaluate our system with two experimental studies: (1) accuracy and repeatability of manual fracture reduction and (2) accuracy of our automatic virtual bone fracture reduction method. The surgeons achieved a mean accuracy of less than 1 mm for the manual reduction and 1.8 mm (std [Formula: see text] 1.1 mm) for the automatic reduction. 3D haptic-based patient-specific preoperative planning of orthopedic fracture surgery from CT scans is useful and accurate and may have significant advantages for evaluating and planning complex fractures surgery.

Accuracy assessment and characterization of x-ray coded aperture coherent scatter spectral imaging for breast cancer classification

PubMed Central

Lakshmanan, Manu N.; Greenberg, Joel A.; Samei, Ehsan; Kapadia, Anuj J.

2017-01-01

Abstract. Although transmission-based x-ray imaging is the most commonly used imaging approach for breast cancer detection, it exhibits false negative rates higher than 15%. To improve cancer detection accuracy, x-ray coherent scatter computed tomography (CSCT) has been explored to potentially detect cancer with greater consistency. However, the 10-min scan duration of CSCT limits its possible clinical applications. The coded aperture coherent scatter spectral imaging (CACSSI) technique has been shown to reduce scan time through enabling single-angle imaging while providing high detection accuracy. Here, we use Monte Carlo simulations to test analytical optimization studies of the CACSSI technique, specifically for detecting cancer in ex vivo breast samples. An anthropomorphic breast tissue phantom was modeled, a CACSSI imaging system was virtually simulated to image the phantom, a diagnostic voxel classification algorithm was applied to all reconstructed voxels in the phantom, and receiver-operator characteristics analysis of the voxel classification was used to evaluate and characterize the imaging system for a range of parameters that have been optimized in a prior analytical study. The results indicate that CACSSI is able to identify the distribution of cancerous and healthy tissues (i.e., fibroglandular, adipose, or a mix of the two) in tissue samples with a cancerous voxel identification area-under-the-curve of 0.94 through a scan lasting less than 10 s per slice. These results show that coded aperture scatter imaging has the potential to provide scatter images that automatically differentiate cancerous and healthy tissue within ex vivo samples. Furthermore, the results indicate potential CACSSI imaging system configurations for implementation in subsequent imaging development studies. PMID:28331884

Morphology-based three-dimensional segmentation of coronary artery tree from CTA scans

NASA Astrophysics Data System (ADS)

Banh, Diem Phuc T.; Kyprianou, Iacovos S.; Paquerault, Sophie; Myers, Kyle J.

2007-03-01

We developed an algorithm based on a rule-based threshold framework to segment the coronary arteries from angiographic computed tomography (CTA) data. Computerized segmentation of the coronary arteries is a challenging procedure due to the presence of diverse anatomical structures surrounding the heart on cardiac CTA data. The proposed algorithm incorporates various levels of image processing and organ information including region, connectivity and morphology operations. It consists of three successive stages. The first stage involves the extraction of the three-dimensional scaffold of the heart envelope. This stage is semiautomatic requiring a reader to review the CTA scans and manually select points along the heart envelope in slices. These points are further processed using a surface spline-fitting technique to automatically generate the heart envelope. The second stage consists of segmenting the left heart chambers and coronary arteries using grayscale threshold, size and connectivity criteria. This is followed by applying morphology operations to further detach the left and right coronary arteries from the aorta. In the final stage, the 3D vessel tree is reconstructed and labeled using an Isolated Connected Threshold technique. The algorithm was developed and tested on a patient coronary artery CTA that was graciously shared by the Department of Radiology of the Massachusetts General Hospital. The test showed that our method constantly segmented the vessels above 79% of the maximum gray-level and automatically extracted 55 of the 58 coronary segments that can be seen on the CTA scan by a reader. These results are an encouraging step toward our objective of generating high resolution models of the male and female heart that will be subsequently used as phantoms for medical imaging system optimization studies.

Intracardiac ultrasound scanner using a micromachine (MEMS) actuator.

PubMed

Zara, J M; Bobbio, S M; Goodwin-Johansson, S; Smith, S W

2000-01-01

Catheter-based intracardiac ultrasound offers the potential for improved guidance of interventional cardiac procedures. The objective of this research is the development of catheter-based mechanical sector scanners incorporating high frequency ultrasound transducers operating at frequencies up to 20 MHz. The authors' current transducer assembly consists of a single 1.75 mm by 1.75 mm, 20 MHz, PZT element mounted on a 2 mm by 2 mm square, 75 mum thick polyimide table that pivots on 3-mum thick gold plated polyimide hinges. The hinges also serve as the electrical connections to the transducer. This table-mounted transducer is tilted using a miniature linear actuator to produce a sector scan. This linear actuator is an integrated force array (IFA), which is an example of a micromachine, i.e., a microelectromechanical system (MEMS). The IFA is a thin (2.2 mum) polyimide membrane, which consists of a network of hundreds of thousands of micron scale deformable capacitors made from pairs of metallized polyimide plates. IFAs contract with an applied voltage of 30-120 V and have been shown to produce strains as large as 20% and forces of up to 8 dynes. The prototype transducer and actuator assembly was fabricated and interfaced with a GagePCI analog to digital conversion board digitizing 12 bit samples at a rate of 100 MSamples/second housed in a personal computer to create a single channel ultrasound scanner. The deflection of the table transducer in a low viscosity insulating fluid (HFE 7100, 3M) is up to +/-10 degrees at scan rates of 10-60 Hz. Software has been developed to produce real-time sector scans on the PC monitor.

Characterization of Thin Film Materials using SCAN meta-GGA, an Accurate Nonempirical Density Functional

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buda, I. G.; Lane, C.; Barbiellini, B.

We discuss self-consistently obtained ground-state electronic properties of monolayers of graphene and a number of ’beyond graphene’ compounds, including films of transition-metal dichalcogenides (TMDs), using the recently proposed strongly constrained and appropriately normed (SCAN) meta-generalized gradient approximation (meta-GGA) to the density functional theory. The SCAN meta-GGA results are compared with those based on the local density approximation (LDA) as well as the generalized gradient approximation (GGA). As expected, the GGA yields expanded lattices and softened bonds in relation to the LDA, but the SCAN meta-GGA systematically improves the agreement with experiment. Our study suggests the efficacy of the SCAN functionalmore » for accurate modeling of electronic structures of layered materials in high-throughput calculations more generally.« less

Characterization of Thin Film Materials using SCAN meta-GGA, an Accurate Nonempirical Density Functional

DOE PAGES

Buda, I. G.; Lane, C.; Barbiellini, B.; ...

2017-03-23

We discuss self-consistently obtained ground-state electronic properties of monolayers of graphene and a number of ’beyond graphene’ compounds, including films of transition-metal dichalcogenides (TMDs), using the recently proposed strongly constrained and appropriately normed (SCAN) meta-generalized gradient approximation (meta-GGA) to the density functional theory. The SCAN meta-GGA results are compared with those based on the local density approximation (LDA) as well as the generalized gradient approximation (GGA). As expected, the GGA yields expanded lattices and softened bonds in relation to the LDA, but the SCAN meta-GGA systematically improves the agreement with experiment. Our study suggests the efficacy of the SCAN functionalmore » for accurate modeling of electronic structures of layered materials in high-throughput calculations more generally.« less

Dual-wavelength photothermal optical coherence tomography for blood oxygen saturation measurement

NASA Astrophysics Data System (ADS)

Yin, Biwei; Kuranov, Roman V.; McElroy, Austin B.; Milner, Thomas E.

2013-03-01

We report design and demonstration of a dual wavelength photothermal (DWP) optical coherence tomography (OCT) system for imaging of a phantom microvessel and measurement of hemoglobin oxygen saturation (SO2) level. The DWP-OCT system contains a swept-source (SS) two-beam phase-sensitive (PhS) OCT system (1060 nm) and two intensity modulated photothermal excitation lasers (770 nm and 800 nm). The PhS-OCT probe beam (1060 nm) and photothermal excitation beams are combined into one single-mode optical fiber. A galvanometer based two-dimensional achromatic scanning system is designed to provide 14 μm lateral resolution for the PhS-OCT probe beam (1060 nm) and 13 μm lateral resolution for photothermal excitation beams. DWP-OCT system's sensitivity is 102 dB, axial resolution is 13 μm in tissue and uses a real-time digital dispersion compensation algorithm. Noise floor for optical pathlength measurements is 300 pm in the signal frequency range (380-400 Hz) of photothermal modulation frequencies. Blood SO2 level is calculated from measured optical pathlength (op) signal in a 300 μm diameter microvessel phantom introduced by the two photothermal excitation beams. En-face and B-scan images of a phantom microvessel are recorded, and six blood samples' SO2 levels are measured using DWP-OCT and compared with values provided by a commercial blood oximeter. A mathematical model indicates thermal diffusion introduces a systematic artifact that over-estimates SO2 values and is consistent with measured data.

Anatomy and growth pattern of Amazon deep-sea fan as revealed by long-range side-scan sonar (GLORIA) and high-resolution seismic studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Damuth, J.E.; Flood, R.D.; Kowsmann, R.O.

1988-08-01

Imaging of the Amazon deep-sea fan with long-range side-scan sonar (GLORIA) has, for the first time, revealed the anatomy, trends, and growth pattern of distributary channels on this fan. Only one channel-levee system was active at any given time and extended from the Amazon Submarine Canyon downslope onto the lower fan (> 4,200 m). Formation of new channel-levee systems occurred when a currently active channel-levee system was cut off and abandoned through avulsion, and a new channel-levee system was established nearby. Through time, successive channel-levee formation and abandonment built two broad levee complexes consisting of groups of overlapping, coalescing segmentsmore » of channel-levee systems across the present fan surface. These, plus older, now buried levee complexes, indicate that fan growth is radially outward and downslope through development of successive levee complexes. The most striking characteristic of the distributary channels is their intricate, often recurving, meanders with sinuosities of up to 2.5. Cutoffs and abandoned meander loops indicate that the channels migrate laterally through time. Channel bifurcation results predominantly from avulsion when flows breach a channel levee, thereby abandoning the present channel and establishing a new channel-levee segment nearby. No clear evidence of channel branching (i.e., division of a single channel into two active segments) or braiding was observed. 22 figs.« less

Kinematics of mechanical and adhesional micromanipulation under a scanning electron microscope

NASA Astrophysics Data System (ADS)

Saito, Shigeki; Miyazaki, Hideki T.; Sato, Tomomasa; Takahashi, Kunio

2002-11-01

In this paper, the kinematics of mechanical and adhesional micromanipulation using a needle-shaped tool under a scanning electron microscope is analyzed. A mode diagram is derived to indicate the possible micro-object behavior for the specified operational conditions. Based on the diagram, a reasonable method for pick and place operation is proposed. The keys to successful analysis are to introduce adhesional and rolling-resistance factors into the kinematic system consisting of a sphere, a needle-shaped tool, and a substrate, and to consider the time dependence of these factors due to the electron-beam (EB) irradiation. Adhesional force and the lower limit of maximum rolling resistance are evaluated quantitatively in theoretical and experimental ways. This analysis shows that it is possible to control the fracture of either the tool-sphere or substrate-sphere interface of the system selectively by the tool-loading angle and that such a selective fracture of the interfaces enables reliable pick or place operation even under EB irradiation. Although the conventional micromanipulation was not repeatable because the technique was based on an empirically effective method, this analysis should provide us with a guideline to reliable micromanipulation.

Ultraprecise medical applications with ultrafast lasers: corneal surgery with femtosecond lasers

NASA Astrophysics Data System (ADS)

Loesel, Frieder H.; Kurtz, Ron M.; Horvath, Christopher; Sayegh, Samir I.; Mourou, Gerard A.; Bille, Josef F.; Juhasz, Tibor

1999-02-01

We investigated refractive corneal surgery in vivo and in vitro by intrastromal photodisruption using a compact ultrafast femtosecond laser system. Ultrashort-pulsed lasers operating in the femtosecond time regime are associated with significantly smaller and deterministic threshold energies for photodisruption, as well as reduced shock waves and smaller cavitation bubbles than the nanosecond or picosecond lasers. Our reliable all-solid-state laser system was specifically designed for real world medical applications. By scanning the 5 micron focus spot of the laser below the corneal surface, the overlapping small ablation volumes of single pulses resulted in contiguous tissue cutting and vaporization. Pulse energies were typically in the order of a few microjoules. Combination of different scanning patterns enabled us to perform corneal flap cutting, femtosecond-LASIK, and femtosecond intrastromal keratectomy in porcine, rabbit, and primate eyes. The cuts proved to be highly precise and possessed superior dissection and surface quality. Preliminary studies show consistent refractive changes in the in vivo studies. We conclude that the technology is capable to perform a variety of corneal refractive procedures at high precision, offering advantages over current mechanical and laser devices and enabling entirely new approaches for refractive surgery.

High temperature superconductor dc SQUID micro-susceptometer for room temperature objects

NASA Astrophysics Data System (ADS)

Faley, M. I.; Pratt, K.; Reineman, R.; Schurig, D.; Gott, S.; Atwood, C. G.; Sarwinski, R. E.; Paulson, D. N.; Starr, T. N.; Fagaly, R. L.

2004-05-01

We have developed a scanning magnetic microscope (SMM) with 25 µm resolution in spatial position for the magnetic features of room temperature objects. The microscope consists of a high-temperature superconductor (HTS) dc SQUID sensor, suspended in vacuum with a self-adjusting standoff, close spaced liquid nitrogen Dewar, X-Y scanning stage and a computer control system. The HTS SQUIDs were optimized for better spatial and field resolutions for operation at liquid nitrogen temperature. Measured inside a magnetic shield, the 10 pT Hz-1/2 typical noise of the SQUIDs is white down to frequencies of about 10 Hz, increasing up to about 20 pT Hz-1/2 at 1 Hz. The microscope is mounted on actively damped platforms, which negate vibrations from the environment as well as damping internal stepper motor noises. A high-resolution video telescope and a 1 µm precision z-axis positioning system allow a close positioning of the sample under the sensor. The ability of the sensors to operate in unshielded environmental conditions with magnetic fields up to about 15 G allowed us to perform 2D mapping of the local ac and dc susceptibility of the objects.

Zolpidem reduces the blood oxygen level-dependent signal during visual system stimulation

PubMed Central

Licata, Stephanie C.; Lowen, Steven B.; Trksak, George H.; MacLean, Robert R.; Lukas, Scott E.

2011-01-01

Zolpidem is a short-acting imidazopyridine hypnotic that binds at the benzodiazepine binding site on specific GABAA receptors to enhance fast inhibitory neurotransmission. The behavioral and receptor pharmacology of zolpidem has been studied extensively, but little is known about its neuronal substrates in vivo. In the present within-subject, double-blind, and placebo-controlled study, blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) at 3 Tesla was used to assess the effects of zolpidem within the brain. Healthy participants (n=12) were scanned 60 minutes after acute oral administration of zolpidem (0, 5, 10, or 20 mg), and changes in BOLD signal were measured in the visual cortex during presentation of a flashing checkerboard. Heart rate and oxygen saturation were monitored continuously throughout the session. Zolpidem (10 and 20 mg) reduced the robust visual system activation produced by presentation of this stimulus, but had no effects on physiological activity during the fMRI scan. Zolpidem’s modulation of the BOLD signal within the visual cortex is consistent with the abundant distribution of GABAA receptors localized in this region, as well as previous studies showing a relationship between increased GABA-mediated neuronal inhibition and a reduction in BOLD activation. PMID:21640782

PSD microscopy: a new technique for adaptive local scanning of microscale objects.

PubMed

Rahimi, Mehdi; Shen, Yantao

2017-01-01

A position-sensitive detector/device (PSD) is a sensor that is capable of tracking the location of a laser beam on its surface. PSDs are used in many scientific instruments and technical applications including but not limited to atomic force microscopy, human eye movement monitoring, mirrors or machine tool alignment, vibration analysis, beam position control and so on. This work intends to propose a new application using the PSD. That is a new microscopy system called scanning PSD microscopy. The working mechanism is about putting an object on the surface of the PSD and fast scanning its area with a laser beam. To achieve a high degree of accuracy and precision, a reliable framework was designed using the PSD. In this work, we first tried to improve the PSD reading and its measurement performance. This was done by minimizing the effects of noise, distortion and other disturbing parameters. After achieving a high degree of confidence, the microscopy system can be implemented based on the improved PSD measurement performance. Later to improve the scanning efficiency, we developed an adaptive local scanning system to scan the whole area of the PSD in a short matter of time. It was validated that our comprehensive and adaptive local scanning method can shorten the scanning time in order of hundreds of times in comparison with the traditional raster scanning without losing any important information about the scanned 2D objects. Methods are also introduced to scan very complicated objects with bifurcations and crossings. By incorporating all these methods, the new microscopy system is capable of scanning very complicated objects in the matter of a few seconds with a resolution that is in order of a few micrometers.

Proof of concept demonstration for coherent beam pattern measurements of KID detectors

NASA Astrophysics Data System (ADS)

Davis, Kristina K.; Baryshev, Andrey M.; Jellema, Willem; Yates, Stephen J. C.; Ferrari, Lorenza; Baselmans, Jochem J. A.

2016-07-01

Here we summarize the initial results from a complex field radiation pattern measurement of a kinetic inductance detector instrument. These detectors are phase insensitive and have thus been limited to scalar, or amplitude-only, beam measurements. Vector beam scans, of both amplitude and phase, double the information received in comparison to scalar beam scans. Scalar beam measurements require multiple scans at varying distances along the optical path of the receiver to fully constrain the divergence angle of the optical system and locate the primary focus. Vector scans provide this information with a single scan, reducing the total measurement time required for new systems and also limiting the influence of system instabilities. The vector scan can be taken at any point along the optical axis of the system including the near-field, which makes beam measurements possible for large systems at high frequencies where these measurements may be inconceivable to be tested in-situ. Therefore, the methodology presented here should enable common heterodyne analysis for direct detector instruments. In principle, this coherent measurement strategy allows phase dependent analysis to be performed on any direct-detect receiver instrument.

Ultrafast photon counting applied to resonant scanning STED microscopy.

PubMed

Wu, Xundong; Toro, Ligia; Stefani, Enrico; Wu, Yong

2015-01-01

To take full advantage of fast resonant scanning in super-resolution stimulated emission depletion (STED) microscopy, we have developed an ultrafast photon counting system based on a multigiga sample per second analogue-to-digital conversion chip that delivers an unprecedented 450 MHz pixel clock (2.2 ns pixel dwell time in each scan). The system achieves a large field of view (∼50 × 50 μm) with fast scanning that reduces photobleaching, and advances the time-gated continuous wave STED technology to the usage of resonant scanning with hardware-based time-gating. The assembled system provides superb signal-to-noise ratio and highly linear quantification of light that result in superior image quality. Also, the system design allows great flexibility in processing photon signals to further improve the dynamic range. In conclusion, we have constructed a frontier photon counting image acquisition system with ultrafast readout rate, excellent counting linearity, and with the capacity of realizing resonant-scanning continuous wave STED microscopy with online time-gated detection. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

Comparison of radiation dose, workflow, patient comfort and financial break-even of standard digital radiography and a novel biplanar low-dose X-ray system for upright full-length lower limb and whole spine radiography.

PubMed

Dietrich, Tobias J; Pfirrmann, Christian W A; Schwab, Alexander; Pankalla, Katja; Buck, Florian M

2013-07-01

To compare the radiation dose, workflow, patient comfort, and financial break-even of a standard digital radiography and a biplanar low-dose X-ray system. A standard digital radiography system (Ysio, Siemens Healthcare, Erlangen, Germany) was compared with a biplanar X-ray unit (EOS, EOS imaging, Paris, France) consisting of two X-ray tubes and slot-scanning detectors, arranged at an angle of 90° allowing simultaneous vertical biplanar linear scanning in the upright patient position. We compared data of standing full-length lower limb radiographs and whole spine radiographs of both X-ray systems. Dose-area product was significantly lower for radiographs of the biplanar X-ray system than for the standard digital radiography system (e.g. whole spine radiographs; standard digital radiography system: 392.2 ± 231.7 cGy*cm(2) versus biplanar X-ray system: 158.4 ± 103.8 cGy*cm(2)). The mean examination time was significantly shorter for biplanar radiographs compared with standard digital radiographs (e.g. whole spine radiographs: 449 s vs 248 s). Patients' comfort regarding noise was significantly higher for the standard digital radiography system. The financial break-even point was 2,602 radiographs/year for the standard digital radiography system compared with 4,077 radiographs/year for the biplanar X-ray unit. The biplanar X-ray unit reduces radiation exposure and increases subjective noise exposure to patients. The biplanar X-ray unit demands a higher number of examinations per year for the financial break-even point, despite the lower labour cost per examination due to the shorter examination time.

Speckle averaging system for laser raster-scan image projection

DOEpatents

Tiszauer, D.H.; Hackel, L.A.

1998-03-17

The viewers` perception of laser speckle in a laser-scanned image projection system is modified or eliminated by the addition of an optical deflection system that effectively presents a new speckle realization at each point on the viewing screen to each viewer for every scan across the field. The speckle averaging is accomplished without introduction of spurious imaging artifacts. 5 figs.

Speckle averaging system for laser raster-scan image projection

DOEpatents

Tiszauer, Detlev H.; Hackel, Lloyd A.

1998-03-17

The viewers' perception of laser speckle in a laser-scanned image projection system is modified or eliminated by the addition of an optical deflection system that effectively presents a new speckle realization at each point on the viewing screen to each viewer for every scan across the field. The speckle averaging is accomplished without introduction of spurious imaging artifacts.

Dynamic 3D scanning as a markerless method to calculate multi-segment foot kinematics during stance phase: methodology and first application.

PubMed

Van den Herrewegen, Inge; Cuppens, Kris; Broeckx, Mario; Barisch-Fritz, Bettina; Vander Sloten, Jos; Leardini, Alberto; Peeraer, Louis

2014-08-22

Multi-segmental foot kinematics have been analyzed by means of optical marker-sets or by means of inertial sensors, but never by markerless dynamic 3D scanning (D3DScanning). The use of D3DScans implies a radically different approach for the construction of the multi-segment foot model: the foot anatomy is identified via the surface shape instead of distinct landmark points. We propose a 4-segment foot model consisting of the shank (Sha), calcaneus (Cal), metatarsus (Met) and hallux (Hal). These segments are manually selected on a static scan. To track the segments in the dynamic scan, the segments of the static scan are matched on each frame of the dynamic scan using the iterative closest point (ICP) fitting algorithm. Joint rotations are calculated between Sha-Cal, Cal-Met, and Met-Hal. Due to the lower quality scans at heel strike and toe off, the first and last 10% of the stance phase is excluded. The application of the method to 5 healthy subjects, 6 trials each, shows a good repeatability (intra-subject standard deviations between 1° and 2.5°) for Sha-Cal and Cal-Met joints, and inferior results for the Met-Hal joint (>3°). The repeatability seems to be subject-dependent. For the validation, a qualitative comparison with joint kinematics from a corresponding established marker-based multi-segment foot model is made. This shows very consistent patterns of rotation. The ease of subject preparation and also the effective and easy to interpret visual output, make the present technique very attractive for functional analysis of the foot, enhancing usability in clinical practice. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

A cryogenic scan mechanism for use in Fourier transform spectrometers

NASA Technical Reports Server (NTRS)

Hakun, Claef F.; Blumenstock, Kenneth A.

1995-01-01

This paper describes the requirements, design, assembly and testing of the linear Scan Mechanism (SM) of the Composite Infrared Spectrometer (CIRS) Instrument. The mechanism consists of an over constrained flexible structure, an innovative moving magnet actuator, passive eddy current dampers, a Differential Eddy Current (DEC) sensor, Optical Limit Sensors (OLS), and a launch lock. Although all the components of the mechanism are discussed, the flexible structure and the magnetic components are the primary focus. Several problems encountered and solutions implemented during the development of the scan mechanism are also described.

Development of High Altitude UAV Weather Radars for Hurricane Research

NASA Technical Reports Server (NTRS)

Heymsfield, Gerald; Li, Li-Hua

2005-01-01

A proposed effort within NASA called (ASHE) over the past few years was aimed at studying the genesis of tropical disturbances off the east coast of Africa. This effort was focused on using an instrumented Global Hawk UAV with high altitude (%Ok ft) and long duration (30 h) capability. While the Global Hawk availability remains uncertain, development of two relevant instruments, a Doppler radar (URAD - UAV Radar) and a backscatter lidar (CPL-UAV - Cloud Physics Lidar), are in progress. The radar to be discussed here is based on two previous high-altitude, autonomously operating radars on the NASA ER-2 aircraft, the ER-2 Doppler Radar (EDOP) at X-band (9.6 GHz), and the Cloud Radar System (CRS) at W- band (94 GHz). The nadir-pointing EDOP and CRS radars profile vertical reflectivity structure and vertical Doppler winds in precipitation and clouds, respectively. EDOP has flown in all of the CAMEX flight series to study hurricanes over storms such as Hurricanes Bonnie, Humberto, Georges, Erin, and TS Chantal. These radars were developed at Goddard over the last decade and have been used for satellite algorithm development and validation (TRMM and Cloudsat), and for hurricane and convective storm research. We describe here the development of URAD that will measure wind and reflectivity in hurricanes and other weather systems from a top down, high-altitude view. URAD for the Global Hawk consists of two subsystems both of which are at X-band (9.3-9.6 GHz) and Doppler: a nadir fixed-beam Doppler radar for vertical motion and precipitation measurement, and a Conical scanning radar for horizontal winds in cloud and at the surface, and precipitation structure. These radars are being designed with size, weight, and power consumption suitable for the Global Hawk and other UAV's. The nadir radar uses a magnetron transmitter and the scanning radar uses a TWT transmitter. With conical scanning of the radar at a 35" incidence angle over an ocean surface in the absence of precipitation, the surface return over a single 360 degree sweep over -25 h-diameter region provides information on the surface wind speed and direction within the scan circle. In precipitation regions, the conical scan with appropriate mapping and analysis provides the 3D structure of reflectivity beneath the plane and the horizontal winds. The use of conical scanning in hurricanes has recently been demonstrated for measuring inner core winds with the IWRAP system flying on the NOAA P3's. In this presentation, we provide a description of the URAD system hardware, status, and future plans. In addition to URAD, NASA SBIR activity is supporting a Phase I study by Remote Sensing Solutions and the University of Massachusetts for a dual-frequency IWRAP for a high altitude UAV that utilizes solid state transmitters at 14 and 35 GHz, the same frequencies that are planned for the radar on the Global Precipitation System satellite. This will be discussed elsewhere at the meeting.

Multiline radar scan

NASA Technical Reports Server (NTRS)

Levinson, S.

1977-01-01

Scanning scheme is more efficient than conventional scanning. Originally designed for optical radar in space vehicles, scheme may also find uses in site-surveillance security systems and in other industrial applications. It should be particularly useful when system must run on battery energy, as would be case in power outages.

Conical scan impact study. Volume 2: Small local user data processing facility. [multispectral band scanner design alternatives for earth resources data

NASA Technical Reports Server (NTRS)

Ebert, D. H.; Chase, P. E.; Dye, J.; Fahline, W. C.; Johnson, R. H.

1973-01-01

The impact of a conical scan versus a linear scan multispectral scanner (MSS) instrument on a small local-user data processing facility was studied. User data requirements were examined to determine the unique system rquirements for a low cost ground system (LCGS) compatible with the Earth Observatory Satellite (EOS) system. Candidate concepts were defined for the LCGS and preliminary designs were developed for selected concepts. The impact of a conical scan MSS versus a linear scan MSS was evaluated for the selected concepts. It was concluded that there are valid user requirements for the LCGS and, as a result of these requirements, the impact of the conical scanner is minimal, although some new hardware development for the LCGS is necessary to handle conical scan data.

A dual cone-beam CT system for image guided radiotherapy: initial performance characterization.

PubMed

Li, Hao; Giles, William; Bowsher, James; Yin, Fang-Fang

2013-02-01

The purpose of this study is to evaluate the performance of a recently developed benchtop dual cone-beam computed tomography (CBCT) system with two orthogonally placed tube∕detector sets. The benchtop dual CBCT system consists of two orthogonally placed 40 × 30 cm flat-panel detectors and two conventional x-ray tubes with two individual high-voltage generators sharing the same rotational axis. The x-ray source to detector distance is 150 cm and x-ray source to rotational axis distance is 100 cm for both subsystems. The objects are scanned through 200° of rotation. The dual CBCT system utilized 110° of projection data from one detector and 90° from the other while the two individual single CBCTs utilized 200° data from each detector. The system performance was characterized in terms of uniformity, contrast, spatial resolution, noise power spectrum, and CT number linearity. The uniformities, within the axial slice and along the longitudinal direction, and noise power spectrum were assessed by scanning a water bucket; the contrast and CT number linearity were measured using the Catphan phantom; and the spatial resolution was evaluated using a tungsten wire phantom. A skull phantom and a ham were also scanned to provide qualitative evaluation of high- and low-contrast resolution. Each measurement was compared between dual and single CBCT systems. Compared to single CBCT, the dual CBCT presented: (1) a decrease in uniformity by 1.9% in axial view and 1.1% in the longitudinal view, as averaged for four energies (80, 100, 125, and 150 kVp); (2) comparable or slightly better contrast (0∼25 HU) for low-contrast objects and comparable contrast for high-contrast objects; (3) comparable spatial resolution; (4) comparable CT number linearity with R(2) ≥ 0.99 for all four tested energies; (5) lower noise power spectrum in magnitude. Dual CBCT images of the skull phantom and the ham demonstrated both high-contrast resolution and good soft-tissue contrast. The performance of a benchtop dual CBCT imaging system has been characterized and is comparable to that of a single CBCT.

A feasibility and optimization study to determine cooling time and burnup of advanced test reactor fuels using a nondestructive technique

NASA Astrophysics Data System (ADS)

Navarro, Jorge

The goal of this study presented is to determine the best available nondestructive technique necessary to collect validation data as well as to determine burnup and cooling time of the fuel elements on-site at the Advanced Test Reactor (ATR) canal. This study makes a recommendation of the viability of implementing a permanent fuel scanning system at the ATR canal and leads to the full design of a permanent fuel scan system. The study consisted at first in determining if it was possible and which equipment was necessary to collect useful spectra from ATR fuel elements at the canal adjacent to the reactor. Once it was establish that useful spectra can be obtained at the ATR canal, the next step was to determine which detector and which configuration was better suited to predict burnup and cooling time of fuel elements nondestructively. Three different detectors of High Purity Germanium (HPGe), Lanthanum Bromide (LaBr3), and High Pressure Xenon (HPXe) in two system configurations of above and below the water pool were used during the study. The data collected and analyzed were used to create burnup and cooling time calibration prediction curves for ATR fuel. The next stage of the study was to determine which of the three detectors tested was better suited for the permanent system. From spectra taken and the calibration curves obtained, it was determined that although the HPGe detector yielded better results, a detector that could better withstand the harsh environment of the ATR canal was needed. The in-situ nature of the measurements required a rugged fuel scanning system, low in maintenance and easy to control system. Based on the ATR canal feasibility measurements and calibration results, it was determined that the LaBr3 detector was the best alternative for canal in-situ measurements; however, in order to enhance the quality of the spectra collected using this scintillator, a deconvolution method was developed. Following the development of the deconvolution method for ATR applications, the technique was tested using one-isotope, multi-isotope, and fuel simulated sources. Burnup calibrations were perfomed using convoluted and deconvoluted data. The calibrations results showed burnup prediction by this method improves using deconvolution. The final stage of the deconvolution method development was to perform an irradiation experiment in order to create a surrogate fuel source to test the deconvolution method using experimental data. A conceptual design of the fuel scan system is path forward using the rugged LaBr 3 detector in an above the water configuration and deconvolution algorithms.

Postprocessing Algorithm for Driving Conventional Scanning Tunneling Microscope at Fast Scan Rates

PubMed Central

Zhang, Hao; Li, Xianqi; Park, Jewook; Li, An-Ping

2017-01-01

We present an image postprocessing framework for Scanning Tunneling Microscope (STM) to reduce the strong spurious oscillations and scan line noise at fast scan rates and preserve the features, allowing an order of magnitude increase in the scan rate without upgrading the hardware. The proposed method consists of two steps for large scale images and four steps for atomic scale images. For large scale images, we first apply for each line an image registration method to align the forward and backward scans of the same line. In the second step we apply a “rubber band” model which is solved by a novel Constrained Adaptive and Iterative Filtering Algorithm (CIAFA). The numerical results on measurement from copper(111) surface indicate the processed images are comparable in accuracy to data obtained with a slow scan rate, but are free of the scan drift error commonly seen in slow scan data. For atomic scale images, an additional first step to remove line-by-line strong background fluctuations and a fourth step of replacing the postprocessed image by its ranking map as the final atomic resolution image are required. The resulting image restores the lattice image that is nearly undetectable in the original fast scan data. PMID:29362664

Development of a hybrid atomic force microscopic measurement system combined with white light scanning interferometry.

PubMed

Guo, Tong; Wang, Siming; Dorantes-Gonzalez, Dante J; Chen, Jinping; Fu, Xing; Hu, Xiaotang

2012-01-01

A hybrid atomic force microscopic (AFM) measurement system combined with white light scanning interferometry for micro/nanometer dimensional measurement is developed. The system is based on a high precision large-range positioning platform with nanometer accuracy on which a white light scanning interferometric module and an AFM head are built. A compact AFM head is developed using a self-sensing tuning fork probe. The head need no external optical sensors to detect the deflection of the cantilever, which saves room on the head, and it can be directly fixed under an optical microscopic interferometric system. To enhance the system's dynamic response, the frequency modulation (FM) mode is adopted for the AFM head. The measuring data can be traceable through three laser interferometers in the system. The lateral scanning range can reach 25 mm × 25 mm by using a large-range positioning platform. A hybrid method combining AFM and white light scanning interferometry is proposed to improve the AFM measurement efficiency. In this method, the sample is measured firstly by white light scanning interferometry to get an overall coarse morphology, and then, further measured with higher resolution by AFM. Several measuring experiments on standard samples demonstrate the system's good measurement performance and feasibility of the hybrid measurement method.

Studies on two-gap superconductivity in 2H-NbS2

NASA Astrophysics Data System (ADS)

Kačmarčík, J.; Pribulová, Z.; Marcenat, C.; Klein, T.; Rodière, P.; Cario, L.; Samuely, P.

2010-12-01

We present the ac-calorimetry measurements of superconducting 2H-NbS2 in the temperature range down to 0.6 K and magnetic fields up to 8 T. The temperature and magnetic field dependence of the electronic specific heat consistently indicate existence of two superconducting energy gaps in the system - one of them with the coupling ratio below the BCS weak-coupling limit and the other above that value. These results support previous findings by scanning tunneling microscopy and spectroscopy measurements [I. Guillamón, H. Suderow, S. Vieira, L. Cario, et al., Phys. Rev. Lett. 101 (2008) 166407] of two pronounced features in density of states related to a two-gap superconductivity in this system.

Laser Scanning In Inspection

NASA Astrophysics Data System (ADS)

West, Patricia; Baker, Lionel R.

1989-03-01

This paper is a review of the applications of laser scanning in inspection. The reasons for the choice of a laser in flying spot scanning and the optical properties of a laser beam which are of value in a scanning instrument will be given. The many methods of scanning laser beams in both one and two dimensions will be described. The use of one dimensional laser scanners for automatic surface inspection for transmitting and reflective products will be covered in detail, with particular emphasis on light collection techniques. On-line inspection applications which will be mentioned include: photographic film web, metal strip products, paper web, glass sheet, car body paint surfaces and internal cylinder bores. Two dimensional laser scanning is employed in applications where increased resolution, increased depth of focus, and better contrast are required compared with conventional vidicon TV or solid state array cameras. Such examples as special microscope laser scanning systems and a TV compatible system for use in restricted areas of a nuclear reactor will be described. The technical and economic benefits and limitations of laser scanning video systems will be compared with conventional TV and CCD array devices.

Results of a laboratory experiment that tests rotating unbalanced-mass devices for scanning gimbaled payloads and free-flying spacecraft

NASA Technical Reports Server (NTRS)

Alhorn, D. C.; Polites, M. E.

1994-01-01

Rotating unbalanced-mass (RUM) devices are a new way to scan space-based, balloon-borne, and ground-based gimbaled payloads, like x-ray and gamma-ray telescopes. They can also be used to scan free-flying spacecraft. Circular scans, linear scans, and raster scans can be generated. A pair of RUM devices generates the basic scan motion and an auxiliary control system using torque motors, control moment gyros, or reaction wheels keeps the scan centered on the target and produces some complementary motion for raster scanning. Previous analyses and simulation results show that this approach offers significant power savings compared to scanning only with the auxiliary control system, especially with large payloads and high scan frequencies. However, these claims have never been proven until now. This paper describes a laboratory experiment which tests the concept of scanning a gimbaled payload with RUM devices. A description of the experiment is given and test results that prove the concept are presented. The test results are compared with those from a computer simulation model of the experiment and the differences are discussed.

Performance of automatic scanning microscope for nuclear emulsion experiments

NASA Astrophysics Data System (ADS)

Güler, A. Murat; Altınok, Özgür

2015-12-01

The impressive improvements in scanning technology and methods let nuclear emulsion to be used as a target in recent large experiments. We report the performance of an automatic scanning microscope for nuclear emulsion experiments. After successful calibration and alignment of the system, we have reached 99% tracking efficiency for the minimum ionizing tracks that penetrating through the emulsions films. The automatic scanning system is successfully used for the scanning of emulsion films in the OPERA experiment and plan to use for the next generation of nuclear emulsion experiments.

Performance of automatic scanning microscope for nuclear emulsion experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Güler, A. Murat, E-mail: mguler@newton.physics.metu.edu.tr; Altınok, Özgür; Tufts University, Medford, MA 02155

The impressive improvements in scanning technology and methods let nuclear emulsion to be used as a target in recent large experiments. We report the performance of an automatic scanning microscope for nuclear emulsion experiments. After successful calibration and alignment of the system, we have reached 99% tracking efficiency for the minimum ionizing tracks that penetrating through the emulsions films. The automatic scanning system is successfully used for the scanning of emulsion films in the OPERA experiment and plan to use for the next generation of nuclear emulsion experiments.

lidar change detection using building models

NASA Astrophysics Data System (ADS)

Kim, Angela M.; Runyon, Scott C.; Jalobeanu, Andre; Esterline, Chelsea H.; Kruse, Fred A.

2014-06-01

Terrestrial LiDAR scans of building models collected with a FARO Focus3D and a RIEGL VZ-400 were used to investigate point-to-point and model-to-model LiDAR change detection. LiDAR data were scaled, decimated, and georegistered to mimic real world airborne collects. Two physical building models were used to explore various aspects of the change detection process. The first model was a 1:250-scale representation of the Naval Postgraduate School campus in Monterey, CA, constructed from Lego blocks and scanned in a laboratory setting using both the FARO and RIEGL. The second model at 1:8-scale consisted of large cardboard boxes placed outdoors and scanned from rooftops of adjacent buildings using the RIEGL. A point-to-point change detection scheme was applied directly to the point-cloud datasets. In the model-to-model change detection scheme, changes were detected by comparing Digital Surface Models (DSMs). The use of physical models allowed analysis of effects of changes in scanner and scanning geometry, and performance of the change detection methods on different types of changes, including building collapse or subsistence, construction, and shifts in location. Results indicate that at low false-alarm rates, the point-to-point method slightly outperforms the model-to-model method. The point-to-point method is less sensitive to misregistration errors in the data. Best results are obtained when the baseline and change datasets are collected using the same LiDAR system and collection geometry.

A Spectrum Sensing Network for Cognitive PMSE Systems

NASA Astrophysics Data System (ADS)

Brendel, Johannes; Riess, Steffen; Stoeckle, Andreas; Rummel, Rafael; Fischer, Georg

2012-09-01

This article is about a Spectrum Sensing Network (SSN) which generates an accurate radio environment map (e.g. power over frequency, time, and location) from a given application area. It is intended to be used in combination with cognitive Program Making and Special Events (PMSE) devices (e.g. wireless microphones) to improve their operation reliability. The SSN consists of a distributed network of multiple scanning radio receivers and a central data management and storage unit. The parts of the SSN are presented in detail and the advantages and use cases of such a sensing network structure will be outlined.

A fast MEMS scanning photoacoustic microscopy system and its application in glioma study

NASA Astrophysics Data System (ADS)

Bi, Renzhe; Balasundaram, Ghayathri; Jeon, Seungwan; Pu, Yang; Tay, Hui Chien; Kim, Chulhong; Olivo, Malini

2018-02-01

We present a water-proof Microelectromechanical systems (MEMS) based scanning optical resolution Photoacoustic Microscopy (OR-PAM) system and its application in glioma tumor mouse model study. The presented OR-PAM system has high optical resolution ( 3 μm) and high scanning speed (up to 50 kHz A-scan rate), which is ideal for cerebral vascular imaging. In this study, the mice with glioma tumor are treated with vascular disrupting agent (VDA). OR-PAM system is utilized to image the cerebral with the whole skull intact before and after the injection of VDA. By image registration, the response of every single blood vessel can be traced. This will provide us deeper understanding of the drug effect.

Reconstruction-of-difference (RoD) imaging for cone-beam CT neuro-angiography

NASA Astrophysics Data System (ADS)

Wu, P.; Stayman, J. W.; Mow, M.; Zbijewski, W.; Sisniega, A.; Aygun, N.; Stevens, R.; Foos, D.; Wang, X.; Siewerdsen, J. H.

2018-06-01

Timely evaluation of neurovasculature via CT angiography (CTA) is critical to the detection of pathology such as ischemic stroke. Cone-beam CTA (CBCT-A) systems provide potential advantages in the timely use at the point-of-care, although challenges of a relatively slow gantry rotation speed introduce tradeoffs among image quality, data consistency and data sparsity. This work describes and evaluates a new reconstruction-of-difference (RoD) approach that is robust to such challenges. A fast digital simulation framework was developed to test the performance of the RoD over standard reference reconstruction methods such as filtered back-projection (FBP) and penalized likelihood (PL) over a broad range of imaging conditions, grouped into three scenarios to test the trade-off between data consistency, data sparsity and peak contrast. Two experiments were also conducted using a CBCT prototype and an anthropomorphic neurovascular phantom to test the simulation findings in real data. Performance was evaluated primarily in terms of normalized root mean square error (NRMSE) in comparison to truth, with reconstruction parameters chosen to optimize performance in each case to ensure fair comparison. The RoD approach reduced NRMSE in reconstructed images by up to 50%–53% compared to FBP and up to 29%–31% compared to PL for each scenario. Scan protocols well suited to the RoD approach were identified that balance tradeoffs among data consistency, sparsity and peak contrast—for example, a CBCT-A scan with 128 projections acquired in 8.5 s over a 180°  +  fan angle half-scan for a time attenuation curve with ~8.5 s time-to-peak and 600 HU peak contrast. With imaging conditions such as the simulation scenarios of fixed data sparsity (i.e. varying levels of data consistency and peak contrast), the experiments confirmed the reduction of NRMSE by 34% and 17% compared to FBP and PL, respectively. The RoD approach demonstrated superior performance in 3D angiography compared to FBP and PL in all simulation and physical experiments, suggesting the possibility of CBCT-A on low-cost, mobile imaging platforms suitable to the point-of-care. The algorithm demonstrated accurate reconstruction with a high degree of robustness against data sparsity and inconsistency.

The fast and accurate 3D-face scanning technology based on laser triangle sensors

NASA Astrophysics Data System (ADS)

Wang, Jinjiang; Chang, Tianyu; Ge, Baozhen; Tian, Qingguo; Chen, Yang; Kong, Bin

2013-08-01

A laser triangle scanning method and the structure of 3D-face measurement system were introduced. In presented system, a liner laser source was selected as an optical indicated signal in order to scanning a line one times. The CCD image sensor was used to capture image of the laser line modulated by human face. The system parameters were obtained by system calibrated calculated. The lens parameters of image part of were calibrated with machine visual image method and the triangle structure parameters were calibrated with fine wire paralleled arranged. The CCD image part and line laser indicator were set with a linear motor carry which can achieve the line laser scanning form top of the head to neck. For the nose is ledge part and the eyes are sunk part, one CCD image sensor can not obtain the completed image of laser line. In this system, two CCD image sensors were set symmetric at two sides of the laser indicator. In fact, this structure includes two laser triangle measure units. Another novel design is there laser indicators were arranged in order to reduce the scanning time for it is difficult for human to keep static for longer time. The 3D data were calculated after scanning. And further data processing include 3D coordinate refine, mesh calculate and surface show. Experiments show that this system has simply structure, high scanning speed and accurate. The scanning range covers the whole head of adult, the typical resolution is 0.5mm.

Design study of a raster scanning system for moving target irradiation in heavy-ion radiotherapy.

PubMed

Furukawa, Takuji; Inaniwa, Taku; Sato, Shinji; Tomitani, Takehiro; Minohara, Shinichi; Noda, Koji; Kanai, Tatsuaki

2007-03-01

A project to construct a new treatment facility as an extension of the existing heavy-ion medical accelerator in chiba (HIMAC) facility has been initiated for further development of carbon-ion therapy. The greatest challenge of this project is to realize treatment of a moving target by scanning irradiation. For this purpose, we decided to combine the rescanning technique and the gated irradiation method. To determine how to avoid hot and/or cold spots by the relatively large number of rescannings within an acceptable irradiation time, we have studied the scanning strategy, scanning magnets and their control, and beam intensity dynamic control. We have designed a raster scanning system and carried out a simulation of irradiating moving targets. The result shows the possibility of practical realization of moving target irradiation with pencil beam scanning. We describe the present status of our design study of the raster scanning system for the HIMAC new treatment facility.

Simulation of fMRI signals to validate dynamic causal modeling estimation

NASA Astrophysics Data System (ADS)

Anandwala, Mobin; Siadat, Mohamad-Reza; Hadi, Shamil M.

2012-03-01

Through cognitive tasks certain brain areas are activated and also receive increased blood to them. This is modeled through a state system consisting of two separate parts one that deals with the neural node stimulation and the other blood response during that stimulation. The rationale behind using this state system is to validate existing analysis methods such as DCM to see what levels of noise they can handle. Using the forward Euler's method this system was approximated in a series of difference equations. What was obtained was the hemodynamic response for each brain area and this was used to test an analysis tool to estimate functional connectivity between each brain area with a given amount of noise. The importance of modeling this system is to not only have a model for neural response but also to compare to actual data obtained through functional imaging scans.

A cargo inspection system based on pulsed fast neutron analysis (PFNA).

PubMed

Ipe, N E; Olsher, R; Ryge, P; Mrozack, J; Thieu, J

2005-01-01

A cargo inspection system based on pulsed fast neutron analysis (PFNA) is to be used at a border crossing to detect explosives and contraband hidden in trucks and cargo containers. Neutrons are produced by the interaction of deuterons in a deuterium target mounted on a moveable scan arm. The collimated pulsed fast neutron beam is used to determine the location and composition of objects in a cargo container. The neutrons produce secondary gamma rays that are characteristic of the object's elemental composition. The cargo inspection system building consists of an accelerator room and an inspection tunnel. The accelerator room is shielded and houses the injector, accelerator and the neutron production gas target. The inspection tunnel is partially shielded. The truck or container to be inspected will be moved through the inspection tunnel by a conveyor system. The facility and radiation source terms considered in the shielding design are described.

Developments on a SEM-based X-ray tomography system: Stabilization scheme and performance evaluation

NASA Astrophysics Data System (ADS)

Gomes Perini, L. A.; Bleuet, P.; Filevich, J.; Parker, W.; Buijsse, B.; Kwakman, L. F. Tz.

2017-06-01

Recent improvements in a SEM-based X-ray tomography system are described. In this type of equipment, X-rays are generated through the interaction between a highly focused electron-beam and a geometrically confined anode target. Unwanted long-term drifts of the e-beam can lead to loss of X-ray flux or decrease of spatial resolution in images. To circumvent this issue, a closed-loop control using FFT-based image correlation is integrated to the acquisition routine, in order to provide an in-line drift correction. The X-ray detection system consists of a state-of-the-art scientific CMOS camera (indirect detection), featuring high quantum efficiency (˜60%) and low read-out noise (˜1.2 electrons). The system performance is evaluated in terms of resolution, detectability, and scanning times for applications covering three different scientific fields: microelectronics, technical textile, and material science.

A Complex Endomembrane System in the Archaeon Ignicoccus hospitalis Tapped by Nanoarchaeum equitans

DOE PAGES

Heimerl, Thomas; Flechsler, Jennifer; Pickl, Carolin; ...

2017-06-13

Based on serial sectioning, focused ion beam scanning electron microscopy (FIB/SEM), and electron tomography, we depict in detail the highly unusual anatomy of the marine hyperthermophilic crenarchaeon, Ignicoccus hospitalis. Our data support a complex and dynamic endomembrane system consisting of cytoplasmic protrusions, and with secretory function. Moreover, we reveal that the cytoplasm of the putative archaeal ectoparasite Nanoarchaeum equitans can get in direct contact with this endomembrane system, complementing and explaining recent proteomic, transcriptomic and metabolomic data on this inter-archaeal relationship. In addition, we identified a matrix of filamentous structures and/or tethers in the voluminous inter-membrane compartment (IMC) of I.more » hospitalis, which might be responsible for membrane dynamics. Overall, this unusual cellular compartmentalization, ultrastructure and dynamics in an archaeon that belongs to the recently proposed TACK superphylum prompts speculation that the eukaryotic endomembrane system might originate from Archaea.« less

New superconducting cyclotron driven scanning proton therapy systems

NASA Astrophysics Data System (ADS)

Klein, Hans-Udo; Baumgarten, Christian; Geisler, Andreas; Heese, Jürgen; Hobl, Achim; Krischel, Detlef; Schillo, Michael; Schmidt, Stefan; Timmer, Jan

2005-12-01

Since one and a half decades ACCEL is investing in development and engineering of state of the art particle-therapy systems. A new medical superconducting 250 MeV proton cyclotron with special focus on the present and future beam requirements of fast scanning treatment systems has been designed. The first new ACCEL medical proton cyclotron is under commissioning at PSI for their PROSCAN proton therapy facility having undergone successful factory tests especially of the closed loop cryomagnetic system. The second cyclotron is part of ACCEL's integrated proton therapy system for Europe's first clinical center, RPTC in Munich. The cyclotron, the energy selection system, the beamline as well as the four gantries and patient positioners have been installed. The scanning system and major parts of the control software have already been tested. We will report on the concept of ACCEL's superconducting cyclotron driven scanning proton therapy systems and the current status of the commissioning work at PSI and RPTC.

Interactive lung segmentation in abnormal human and animal chest CT scans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kockelkorn, Thessa T. J. P., E-mail: thessa@isi.uu.nl; Viergever, Max A.; Schaefer-Prokop, Cornelia M.

2014-08-15

Purpose: Many medical image analysis systems require segmentation of the structures of interest as a first step. For scans with gross pathology, automatic segmentation methods may fail. The authors’ aim is to develop a versatile, fast, and reliable interactive system to segment anatomical structures. In this study, this system was used for segmenting lungs in challenging thoracic computed tomography (CT) scans. Methods: In volumetric thoracic CT scans, the chest is segmented and divided into 3D volumes of interest (VOIs), containing voxels with similar densities. These VOIs are automatically labeled as either lung tissue or nonlung tissue. The automatic labeling resultsmore » can be corrected using an interactive or a supervised interactive approach. When using the supervised interactive system, the user is shown the classification results per slice, whereupon he/she can adjust incorrect labels. The system is retrained continuously, taking the corrections and approvals of the user into account. In this way, the system learns to make a better distinction between lung tissue and nonlung tissue. When using the interactive framework without supervised learning, the user corrects all incorrectly labeled VOIs manually. Both interactive segmentation tools were tested on 32 volumetric CT scans of pigs, mice and humans, containing pulmonary abnormalities. Results: On average, supervised interactive lung segmentation took under 9 min of user interaction. Algorithm computing time was 2 min on average, but can easily be reduced. On average, 2.0% of all VOIs in a scan had to be relabeled. Lung segmentation using the interactive segmentation method took on average 13 min and involved relabeling 3.0% of all VOIs on average. The resulting segmentations correspond well to manual delineations of eight axial slices per scan, with an average Dice similarity coefficient of 0.933. Conclusions: The authors have developed two fast and reliable methods for interactive lung segmentation in challenging chest CT images. Both systems do not require prior knowledge of the scans under consideration and work on a variety of scans.« less

AMSR2 Soil Moisture Product Validation

NASA Technical Reports Server (NTRS)

Bindlish, R.; Jackson, T.; Cosh, M.; Koike, T.; Fuiji, X.; de Jeu, R.; Chan, S.; Asanuma, J.; Berg, A.; Bosch, D.;

Verification of intensity modulated radiation therapy beams using a tissue equivalent plastic scintillator dosimetry system

NASA Astrophysics Data System (ADS)

Petric, Martin Peter

This thesis describes the development and implementation of a novel method for the dosimetric verification of intensity modulated radiation therapy (IMRT) fields with several advantages over current techniques. Through the use of a tissue equivalent plastic scintillator sheet viewed by a charge-coupled device (CCD) camera, this method provides a truly tissue equivalent dosimetry system capable of efficiently and accurately performing field-by-field verification of IMRT plans. This work was motivated by an initial study comparing two IMRT treatment planning systems. The clinical functionality of BrainLAB's BrainSCAN and Varian's Helios IMRT treatment planning systems were compared in terms of implementation and commissioning, dose optimization, and plan assessment. Implementation and commissioning revealed differences in the beam data required to characterize the beam prior to use with the BrainSCAN system requiring higher resolution data compared to Helios. This difference was found to impact on the ability of the systems to accurately calculate dose for highly modulated fields, with BrainSCAN being more successful than Helios. The dose optimization and plan assessment comparisons revealed that while both systems use considerably different optimization algorithms and user-control interfaces, they are both capable of producing substantially equivalent dose plans. The extensive use of dosimetric verification techniques in the IMRT treatment planning comparison study motivated the development and implementation of a novel IMRT dosimetric verification system. The system consists of a water-filled phantom with a tissue equivalent plastic scintillator sheet built into the top surface. Scintillation light is reflected by a plastic mirror within the phantom towards a viewing window where it is captured using a CCD camera. Optical photon spread is removed using a micro-louvre optical collimator and by deconvolving a glare kernel from the raw images. Characterization of this new dosimetric verification system indicates excellent dose response and spatial linearity, high spatial resolution, and good signal uniformity and reproducibility. Dosimetric results from square fields, dynamic wedged fields, and a 7-field head and neck IMRT treatment plan indicate good agreement with film dosimetry distributions. Efficiency analysis of the system reveals a 50% reduction in time requirements for field-by-field verification of a 7-field IMRT treatment plan compared to film dosimetry.

Phase relations in the system NaCl-KCl-H2O: IV. Differential thermal analysis of the sylvite liquidus in the KCl-H2O binary, the liquidus in the NaCl-KCl-H2O ternary, and the solidus in the NaCl-KCl binary to 2 kb pressure, and a summary of experimental data for thermodynamic-PTX analysis of solid-liquid equilibria at elevated P-T conditions

USGS Publications Warehouse

Chou, I.-Ming; Sterner, S.M.; Pitzer, Kenneth S.

1992-01-01

The sylvite liquidus in the binary system KCl-H2O and the liquidus in the ternary system NaCl-KCl-H2O were determined by using isobaric differential thermal analysis (DTA) cooling scans at pressures up to 2 kbars. Sylvite solubilities along the three-phase curve in the binary system KCl-H2O were obtained by the intersection of sylvite-liquidus isopleths with the three-phase curve in a P-T plot. These solubility data can be represented by the equation Wt.% KCl (??0.2) = 12.19 + 0.1557T - 5.4071 ?? 10-5 T2, where 400 ??? T ??? 770??C. These data are consistent with previous experimental observations. The solidus in the binary system NaCl-KCl was determined by using isobaric DTA heating scans at pressures up to 2 kbars. Using these liquidus and solidus data and other published information, a thermodynamic-PTX analysis of solid-liquid equilibria at high pressures and temperatures for the ternary system has been performed and is presented in an accompanying paper (Part V of this series). However, all experimental liquidus, solidus, and solvus data used in this analysis are summarized in this report (Part IV) and they are compared with the calculated values based on the analysis. ?? 1992.

Symmetry-Breaking Phase Transition without a Peierls Instability in Conducting Monoatomic Chains

NASA Astrophysics Data System (ADS)

Blumenstein, C.; Schäfer, J.; Morresi, M.; Mietke, S.; Matzdorf, R.; Claessen, R.

2011-10-01

The one-dimensional (1D) model system Au/Ge(001), consisting of linear chains of single atoms on a surface, is scrutinized for lattice instabilities predicted in the Peierls paradigm. By scanning tunneling microscopy and electron diffraction we reveal a second-order phase transition at 585 K. It leads to charge ordering with transversal and vertical displacements and complex interchain correlations. However, the structural phase transition is not accompanied by the electronic signatures of a charge density wave, thus precluding a Peierls instability as origin. Instead, this symmetry-breaking transition exhibits three-dimensional critical behavior. This reflects a dichotomy between the decoupled 1D electron system and the structural elements that interact via the substrate. Such substrate-mediated coupling between the wires thus appears to have been underestimated also in related chain systems.

Webcam autofocus mechanism used as a delay line for the characterization of femtosecond pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castro-Marín, Pablo; Kapellmann-Zafra, Gabriel; Garduño-Mejía, Jesús, E-mail: jesus.garduno@ccadet.unam.mx

2015-08-15

In this work, we present an electromagnetic focusing mechanism (EFM), from a commercial webcam, implemented as a delay line of a femtosecond laser pulse characterization system. The characterization system consists on a second order autocorrelator based on a two-photon-absorption detection. The results presented here were performed for two different home-made femtosecond oscillators: Ti:sapph @ 820 nm and highly chirped pulses generated with an Erbium Doped Fiber @ 1550 nm. The EFM applied as a delay line represents an excellent alternative due its performance in terms of stability, resolution, and long scan range up to 3 ps. Due its low powermore » consumption, the device can be connected through the Universal Serial Bus (USB) port. Details of components, schematics of electronic controls, and detection systems are presented.« less

Structure-From-Motion in 3D Space Using 2D Lidars

PubMed Central

Choi, Dong-Geol; Bok, Yunsu; Kim, Jun-Sik; Shim, Inwook; Kweon, In So

2017-01-01

This paper presents a novel structure-from-motion methodology using 2D lidars (Light Detection And Ranging). In 3D space, 2D lidars do not provide sufficient information for pose estimation. For this reason, additional sensors have been used along with the lidar measurement. In this paper, we use a sensor system that consists of only 2D lidars, without any additional sensors. We propose a new method of estimating both the 6D pose of the system and the surrounding 3D structures. We compute the pose of the system using line segments of scan data and their corresponding planes. After discarding the outliers, both the pose and the 3D structures are refined via nonlinear optimization. Experiments with both synthetic and real data show the accuracy and robustness of the proposed method. PMID:28165372

Ultrasonic scanning system for in-place inspection of brazed-tube joints

NASA Technical Reports Server (NTRS)

Haralson, H. S.; Haynes, J. L.; Wages, C. G.

1971-01-01

System detects defects of .051 cm in diameter and larger. System incorporates scanning head assembly including boot enclosed transducer, slip ring assembly, drive mechanism, and servotransmitter. Ultrasonic flaw detector, prototype recorder, and special recorder complete system.

Microstructural and Defect Characterization in Ceramic Composites Using an Ultrasonic Guided Wave Scan System

NASA Technical Reports Server (NTRS)

Roth, D. J.; Cosgriff, L. M.; Martin, R. E.; Verrilli, M. J.; Bhatt, R. T.

2003-01-01

In this study, an ultrasonic guided wave scan system was used to characterize various microstructural and flaw conditions in two types of ceramic matrix composites, SiC/SiC and C/SiC. Rather than attempting to isolate specific lamb wave modes to use for characterization (as is desired for many types of guided wave inspection problems), the guided wave scan system utilizes the total (multi-mode) ultrasonic response in its inspection analysis. Several time and frequency-domain parameters are calculated from the ultrasonic guided wave signal at each scan location to form images. Microstructural and defect conditions examined include delamination, density variation, cracking, and pre/ post-infiltration. Results are compared with thermographic imaging methods. Although the guided wave technique is commonly used so scanning can be eliminated, applying the technique in the scanning mode allows a more precise characterization of defect conditions.

[Microinjection Monitoring System Design Applied to MRI Scanning].

PubMed

Xu, Yongfeng

2017-09-30

A microinjection monitoring system applied to the MRI scanning was introduced. The micro camera probe was used to stretch into the main magnet for real-time video injection monitoring of injection tube terminal. The programming based on LabVIEW was created to analysis and process the real-time video information. The feedback signal was used for intelligent controlling of the modified injection pump. The real-time monitoring system can make the best use of injection under the condition that the injection device was away from the sample which inside the magnetic room and unvisible. 9.4 T MRI scanning experiment showed that the system in ultra-high field can work stability and doesn't affect the MRI scans.

WE-E-BRB-11: Riview a Web-Based Viewer for Radiotherapy.

PubMed

Apte, A; Wang, Y; Deasy, J

2012-06-01

Collaborations involving radiotherapy data collection, such as the recently proposed international radiogenomics consortium, require robust, web-based tools to facilitate reviewing treatment planning information. We present the architecture and prototype characteristics for a web-based radiotherapy viewer. The web-based environment developed in this work consists of the following components: 1) Import of DICOM/RTOG data: CERR was leveraged to import DICOM/RTOG data and to convert to database friendly RT objects. 2) Extraction and Storage of RT objects: The scan and dose distributions were stored as .png files per slice and view plane. The file locations were written to the MySQL database. Structure contours and DVH curves were written to the database as numeric data. 3) Web interfaces to query, retrieve and visualize the RT objects: The Web application was developed using HTML 5 and Ruby on Rails (RoR) technology following the MVC philosophy. The open source ImageMagick library was utilized to overlay scan, dose and structures. The application allows users to (i) QA the treatment plans associated with a study, (ii) Query and Retrieve patients matching anonymized ID and study, (iii) Review up to 4 plans simultaneously in 4 window panes (iv) Plot DVH curves for the selected structures and dose distributions. A subset of data for lung cancer patients was used to prototype the system. Five user accounts were created to have access to this study. The scans, doses, structures and DVHs for 10 patients were made available via the web application. A web-based system to facilitate QA, and support Query, Retrieve and the Visualization of RT data was prototyped. The RIVIEW system was developed using open source and free technology like MySQL and RoR. We plan to extend the RIVIEW system further to be useful in clinical trial data collection, outcomes research, cohort plan review and evaluation. © 2012 American Association of Physicists in Medicine.

Can CT-based patient-matched instrumentation achieve consistent rotational alignment in knee arthroplasty?

PubMed

Tibesku, C O; Innocenti, B; Wong, P; Salehi, A; Labey, L

2012-02-01

Long-term success of contemporary total knee replacements relies to a large extent on proper implant alignment. This study was undertaken to test whether specimen-matched cutting blocks based on computed axial tomography (CT) scans could provide accurate rotational alignment of the femoral component. CT scans of five fresh frozen full leg cadaver specimens, equipped with infrared reflective markers, were used to produce a specimen-matched femoral cutting block. Using those blocks, the bone cuts were made to implant a bi-compartmental femoral component. Rotational alignment of the components in the horizontal plane was determined using an optical measurement system and compared with all relevant rotational reference axes identified on the CT scans. Average rotational alignment for the bi-compartmental component in the horizontal plane was 1.9° (range 0°-6.3°; standard deviation 2.6°). One specimen that showed the highest deviation from the planned alignment also featured a completely degraded medial articular surface. The CT-based specimen-matched cutting blocks achieved good rotational alignment accuracy except for one specimen with badly damaged cartilage. In such cases, imaging techniques that visualize the cartilage layer might be more suitable to design cutting blocks, as they will provide a better fit and increased surface support.

Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

PubMed Central

Lee, Hsiang-Chieh; Ahsen, Osman Oguz; Liang, Kaicheng; Wang, Zhao; Cleveland, Cody; Booth, Lucas; Potsaid, Benjamin; Jayaraman, Vijaysekhar; Cable, Alex E.; Mashimo, Hiroshi; Langer, Robert; Traverso, Giovanni; Fujimoto, James G.

2016-01-01

We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 µm axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 frames per second (fps) with a ~30 µm (FWHM) spot size. Volumetric imaging is achieved by proximal pullback of the micromotor assembly within the balloon at 1.5 mm/sec. Volumetric data consisting of 4200 circumferential images of 5,000 A-scans each over a 2.6 cm length, covering a ~13 cm2 area is acquired in <18 seconds. A non-rigid image registration algorithm is used to suppress motion artifacts from non-uniform rotational distortion (NURD), cardiac motion or respiration. En face OCT images at various depths can be generated. OCT angiography (OCTA) is computed using intensity decorrelation between sequential pairs of circumferential scans and enables three-dimensional visualization of vasculature. Wide area volumetric OCT and OCTA imaging of the swine esophagus in vivo is demonstrated. PMID:27570688

Three-dimensional body scanning system for apparel mass-customization

NASA Astrophysics Data System (ADS)

Xu, Bugao; Huang, Yaxiong; Yu, Weiping; Chen, Tong

2002-07-01

Mass customization is a new manufacturing trend in which mass-market products (e.g., apparel) are quickly modified one at a time based on customers' needs. It is an effective competing strategy for maximizing customers' satisfaction and minimizing inventory costs. An automatic body measurement system is essential for apparel mass customization. This paper introduces the development of a body scanning system, body size extraction methods, and body modeling algorithms. The scanning system utilizes the multiline triangulation technique to rapidly acquire surface data on a body, and provides accurate body measurements, many of which are not available with conventional methods. Cubic B-spline curves are used to connect and smooth body curves. From the scanned data, a body form can be constructed using linear Coons surfaces. The body form can be used as a digital model of the body for 3-D garment design and for virtual try-on of a designed garment. This scanning system and its application software enable apparel manufacturers to provide custom design services to consumers seeking personal-fit garments.

In vitro evaluation of the imaging accuracy of C-arm conebeam CT in cerebral perfusion imaging

PubMed Central

Ganguly, A.; Fieselmann, A.; Boese, J.; Rohkohl, C.; Hornegger, J.; Fahrig, R.

2012-01-01

Purpose: The authors have developed a method to enable cerebral perfusion CT imaging using C-arm based conebeam CT (CBCT). This allows intraprocedural monitoring of brain perfusion during treatment of stroke. Briefly, the technique consists of acquiring multiple scans (each scan comprised of six sweeps) acquired at different time delays with respect to the start of the x-ray contrast agent injection. The projections are then reconstructed into angular blocks and interpolated at desired time points. The authors have previously demonstrated its feasibility in vivo using an animal model. In this paper, the authors describe an in vitro technique to evaluate the accuracy of their method for measuring the relevant temporal signals. Methods: The authors’ evaluation method is based on the concept that any temporal signal can be represented by a Fourier series of weighted sinusoids. A sinusoidal phantom was developed by varying the concentration of iodine as successive steps of a sine wave. Each step corresponding to a different dilution of iodine contrast solution contained in partitions along a cylinder. By translating the phantom along the axis at different velocities, sinusoidal signals at different frequencies were generated. Using their image acquisition and reconstruction algorithm, these sinusoidal signals were imaged with a C-arm system and the 3D volumes were reconstructed. The average value in a slice was plotted as a function of time. The phantom was also imaged using a clinical CT system with 0.5 s rotation. C-arm CBCT results using 6, 3, 2, and 1 scan sequences were compared to those obtained using CT. Data were compared for linear velocities of the phantom ranging from 0.6 to 1 cm/s. This covers the temporal frequencies up to 0.16 Hz corresponding to a frequency range within which 99% of the spectral energy for all temporal signals in cerebral perfusion imaging is contained. Results: The errors in measurement of temporal frequencies are mostly below 2% for all multiscan sequences. For single scan sequences, the errors increase sharply beyond 0.10 Hz. The amplitude errors increase with frequency and with decrease in the number of scans used. Conclusions: Our multiscan perfusion CT approach allows low errors in signal frequency measurement. Increasing the number of scans reduces the amplitude errors. A two-scan sequence appears to offer the best compromise between accuracy and the associated total x-ray and iodine dose. PMID:23127059

Studies of the field-of-view resolution tradeoff in virtual-reality systems

NASA Technical Reports Server (NTRS)

Piantanida, Thomas P.; Boman, Duane; Larimer, James; Gille, Jennifer; Reed, Charles

1992-01-01

Most virtual-reality systems use LCD-based displays that achieve a large field-of-view at the expense of resolution. A typical display will consist of approximately 86,000 pixels uniformly distributed over an 80-degree by 60-degree image. Thus, each pixel subtends about 13 minutes of arc at the retina; about the same as the resolvable features of the 20/200 line of a Snellen Eye Chart. The low resolution of LCD-based systems limits task performance in some applications. We have examined target-detection performance in a low-resolution virtual world. Our synthesized three-dimensional virtual worlds consisted of target objects that could be positioned at a fixed distance from the viewer, but at random azimuth and constrained elevation. A virtual world could be bounded by chromatic walls or by wire-frame, or it could be unbounded. Viewers scanned these worlds and indicated by appropriate gestures when they had detected the target object. By manipulating the viewer's field size and the chromatic and luminance contrast of annuli surrounding the field-of-view, we were able to assess the effect of field size on the detection of virtual objects in low-resolution synthetic worlds.

Conical scan impact study. Volume 1: General central data processing facility. [multispectral band scanner design alternatives for earth resources data

NASA Technical Reports Server (NTRS)

Ebert, D. H.; Eppes, T. A.; Thomas, D. J.

1973-01-01

The impact of a conical scan versus a linear scan multispectral scanner (MSS) instrument was studied in terms of: (1) design modifications required in framing and continuous image recording devices; and (2) changes in configurations of an all-digital precision image processor. A baseline system was defined to provide the framework for comparison, and included pertinent spacecraft parameters, a conical MSS, a linear MSS, an image recording system, and an all-digital precision processor. Lateral offset pointing of the sensors over a range of plus or minus 20 deg was considered. The study addressed the conical scan impact on geometric, radiometric, and aperture correction of MSS data in terms of hardware and software considerations, system complexity, quality of corrections, throughput, and cost of implementation. It was concluded that: (1) if the MSS data are to be only film recorded, then there is only a nomial concial scan impact on the ground data processing system; and (2) if digital data are to be provided to users on computer compatible tapes in rectilinear format, then there is a significant conical scan impact on the ground data processing system.

Recommendations for the design and the installation of large laser scanning microscopy systems

NASA Astrophysics Data System (ADS)

Helm, P. Johannes

2012-03-01

Laser Scanning Microscopy (LSM) has since the inventions of the Confocal Scanning Laser Microscope (CLSM) and the Multi Photon Laser Scanning Microscope (MPLSM) developed into an essential tool in contemporary life science and material science. The market provides an increasing number of turn-key and hands-off commercial LSM systems, un-problematic to purchase, set up and integrate even into minor research groups. However, the successful definition, financing, acquisition, installation and effective use of one or more large laser scanning microscopy systems, possibly of core facility character, often requires major efforts by senior staff members of large academic or industrial units. Here, a set of recommendations is presented, which are helpful during the process of establishing large systems for confocal or non-linear laser scanning microscopy as an effective operational resource in the scientific or industrial production process. Besides the description of technical difficulties and possible pitfalls, the article also illuminates some seemingly "less scientific" processes, i.e. the definition of specific laboratory demands, advertisement of the intention to purchase one or more large systems, evaluation of quotations, establishment of contracts and preparation of the local environment and laboratory infrastructure.

PSIDD3: Post-Scan Ultrasonic Data Display System for the Windows-Based PC Including Fuzzy Logic Analysis

NASA Technical Reports Server (NTRS)

Lovelace, Jeffrey J.; Cios, Krzysztof J.; Roth, Don J.; Cao, Wei

2000-01-01

Post-Scan Interactive Data Display (PSIDD) III is a user-oriented Windows-based system that facilitates the display and comparison of ultrasonic contact data. The system is optimized to compare ultrasonic measurements made at different locations within a material or at different stages of material degradation. PSIDD III provides complete analysis of the primary wave forms in the time and frequency domains along with the calculation of several frequency dependent properties including Phase Velocity and Attenuation Coefficient and several frequency independent properties, like the Cross Correlation Velocity. The system allows image generation on all of the frequency dependent properties at any available frequency (limited by the bandwidth used in the scans) and on any of the frequency independent properties. From ultrasonic contact scans, areas of interest on an image can be studied with regard to underlying raw waveforms and derived ultrasonic properties by simply selecting the point on the image. The system offers various modes of in-depth comparison between scan points. Up to five scan points can be selected for comparative analysis at once. The system was developed with Borland Delphi software (Visual Pascal) and is based on a SQL database. It is ideal for classification of material properties, or location of microstructure variations in materials.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilcox, Ellen; Daskalov, George; Nedialkova, Lucy

Intensity-modulated radiotherapy (IMRT) treatment plan verification is often done using Kodak EDR2 film and a Vidar Dosimetry PRO trade mark sign film digitizer. However, since many hospitals are moving towards a filmless environment, access to a film processor may not be available. Therefore, we have investigated a newly available Gafchromic[reg] EBT film for IMRT dosimetry. Planar IMRT dose distributions are delivered to both EBT and EDR2 film and scanned with the Vidar VXR-16 as well as an Epson Expression 1680 flatbed scanner. The measured dose distributions are then compared to those calculated with a Pinnacle treatment planning system. The IMRTmore » treatments consisted of 7-9 6 MV beams for treatment of prostate, head and neck, and a few other sites. The films were analyzed using FilmQA trade mark sign (3cognition LLC) software. Comparisons between measured and calculated dose distributions are reported as dose difference (DD) (pixels within {+-}5%), distance to agreement (DTA) (3 mm), as well as gamma values ({gamma}) (dose={+-}3%, dist.=2 mm). Using EDR2 with the Vidar scanner is an established technique and agreement between calculated and measured dose distributions was better than 90% in all indices (DD, DTA, and {gamma}). However, agreement with calculations deteriorated reaching the lower 80% for EBT film scans with the Vidar scanner in logarithmic mode. The EBT Vidar scans obtained in linear mode showed an improved agreement to the upper 80% range, but artifacts were still observed across the scan. These artifacts were very distinct in all EBT scans and can be attributed to the way the film is transported through the scanner. In the Epson scanner both films are rigidly immobilized and the light source scans over the film. It was found that the Epson scanner performed equally well with both types of film giving agreement to better than 90% in all indices.« less

Thermal conductivity profile determination in proton-irradiated ZrC by spatial and frequency scanning thermal wave methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, C.; Department of Mechanical and Aerospace Engineering, Utah State University, Logan, Utah 84322; Chirtoc, M.

2013-10-07

Using complementary thermal wave methods, the irradiation damaged region of zirconium carbide (ZrC) is characterized by quantifiably profiling the thermophysical property degradation. The ZrC sample was irradiated by a 2.6 MeV proton beam at 600 °C to a dose of 1.75 displacements per atom. Spatial scanning techniques including scanning thermal microscopy (SThM), lock-in infrared thermography (lock-in IRT), and photothermal radiometry (PTR) were used to directly map the in-depth profile of thermal conductivity on a cross section of the ZrC sample. The advantages and limitations of each system are discussed and compared, finding consistent results from all techniques. SThM provides themore » best resolution finding a very uniform thermal conductivity envelope in the damaged region measuring ∼52 ± 2 μm deep. Frequency-based scanning PTR provides quantification of the thermal parameters of the sample using the SThM measured profile to provide validation of a heating model. Measured irradiated and virgin thermal conductivities are found to be 11.9 ± 0.5 W m{sup −1} K{sup −1} and 26.7 ±1 W m{sup −1} K{sup −1}, respectively. A thermal resistance evidenced in the frequency spectra of the PTR results was calculated to be (1.58 ± 0.1) × 10{sup −6} m{sup 2} K W{sup −1}. The measured thermal conductivity values compare well with the thermal conductivity extracted from the SThM calibrated signal and the spatially scanned PTR. Combined spatial and frequency scanning techniques are shown to provide a valuable, complementary combination for thermal property characterization of proton-irradiated ZrC. Such methodology could be useful for other studies of ion-irradiated materials.« less

A Novel Methodology to Validate the Accuracy of Extraoral Dental Scanners and Digital Articulation Systems.

PubMed

Ellakwa, A; Elnajar, S; Littlefair, D; Sara, G

2018-05-03

The aim of the current study is to develop a novel method to investigate the accuracy of 3D scanners and digital articulation systems. An upper and a lower poured stone model were created by taking impression of fully dentate male (fifty years old) participant. Titanium spheres were added to the models to allow for an easily recognisable geometric shape for measurement after scanning and digital articulation. Measurements were obtained using a Coordinate Measuring Machine to record volumetric error, articulation error and clinical effect error. Three scanners were compared, including the Imetric 3D iScan d104i, Shining 3D AutoScan-DS100 and 3Shape D800, as well as their respective digital articulation software packages. Stoneglass Industries PDC digital articulation system was also applied to the Imetric scans for comparison with the CMM measurements. All the scans displayed low volumetric error (p⟩0.05), indicating that the scanners themselves had a minor contribution to the articulation and clinical effect errors. The PDC digital articulation system was found to deliver the lowest average errors, with good repeatability of results. The new measuring technique in the current study was able to assess the scanning and articulation accuracy of the four systems investigated. The PDC digital articulation system using Imetric scans was recommended as it displayed the lowest articulation error and clinical effect error with good repeatability. The low errors from the PDC system may have been due to its use of a 3D axis for alignment rather than the use of a best fit. Copyright© 2018 Dennis Barber Ltd.

A compact multi-trap optical tweezer system based on CD-ROM technologies

NASA Astrophysics Data System (ADS)

McMenamin, T.; Lee, W. M.

2017-08-01

We implemented an integrated time sharing multiple optical trapping system through the synchronisation of high speed voice coil scanning lens and laser pulsing. The integration is achieved by using commonly available optical pickup unit (OPU) that exists inside optical drives. Scanning frequencies of up to 2 kHz were showed to achieve arbitrary distribution of optical traps within the one-dimensional scan range of the voice coil motor. The functions of the system were demonstrated by the imaging and trapping of 1 μm particles and giant unilamellar vesicles (GUVs). The new device circumvents existing bulky laser scanning systems (4f lens systems) with an integrated laser and lens steering platform that can be integrated on a variety of microscopy platforms (confocal, lightsheet, darkfield).

Low frequency ultrasonic nondestructive inspection of aluminum/adhesive fuselage lap splices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patton, Thadd

1994-01-04

This thesis is a collection of research efforts in ultrasonics, conducted at the Center for Aviation Systems Reliability located at Iowa State University, as part of the Federal Aviation Administration`s ``Aging Aircraft Program.`` The research was directed toward the development of an ultrasonic prototype to inspect the aluminum/adhesive fuselage lap splices found on 1970`s vintage Boeing passenger aircraft. The ultrasonic prototype consists of a normal incidence, low frequency inspection technique, and a scanning adapter that allows focused immersion transducers to be operated in a direct contact manner in any inspection orientation, including upside-down. The inspection technique uses a computer-controlled datamore » acquisition system to produce a C-scan image of a radio frequency (RF) waveform created by a low frequency, broadband, focused beam transducer, driven with a spike voltage pulser. C-scans produced by this technique are color representations of the received signal`s peak-to-peak amplitude (voltage) taken over an (x, y) grid. Low frequency, in this context, refers to a wavelength that is greater than the lap splice`s layer thicknesses. With the low frequency technique, interface echoes of the lap splice are not resolved and gating of the signal is unnecessary; this in itself makes the technique simple to implement and saves considerable time in data acquisition. Along with the advantages in data acquisition, the low frequency technique is relatively insensitive to minor surface curvature and to ultrasonic interference effects caused by adhesive bondline thickness variations in the lap splice.« less

Ultrasonic inspection and deployment apparatus

DOEpatents

Michaels, Jennifer E.; Michaels, Thomas E.; Mech, Jr., Stephen J.

1984-01-01

An ultrasonic inspection apparatus for the inspection of metal structures, especially installed pipes. The apparatus combines a specimen inspection element, an acoustical velocity sensing element, and a surface profiling element, all in one scanning head. A scanning head bellows contains a volume of oil above the pipe surface, serving as acoustical couplant between the scanning head and the pipe. The scanning head is mounted on a scanning truck which is mobile around a circular track surrounding the pipe. The scanning truck has sufficient motors, gears, and position encoders to allow the scanning head six degrees of motion freedom. A computer system continually monitors acoustical velocity, and uses that parameter to process surface profiling and inspection data. The profiling data is used to automatically control scanning head position and alignment and to define a coordinate system used to identify and interpret inspection data. The apparatus is suitable for highly automated, remote application in hostile environments, particularly high temperature and radiation areas.

Recent advances in laser triangulation-based measurement of airfoil surfaces

NASA Astrophysics Data System (ADS)

Hageniers, Omer L.

1995-01-01

The measurement of aircraft jet engine turbine and compressor blades requires a high degree of accuracy. This paper will address the development and performance attributes of a noncontact electro-optical gaging system specifically designed to meet the airfoil dimensional measurement requirements inherent in turbine and compressor blade manufacture and repair. The system described consists of the following key components: a high accuracy, dual channel, laser based optical sensor, a four degree of freedom mechanical manipulator system and a computer based operator interface. Measurement modes of the system include point by point data gathering at rates up to 3 points per second and an 'on-the-fly' mode where points can be gathered at data rates up to 20 points per second at surface scanning speeds of up to 1 inch per second. Overall system accuracy is +/- 0.0005 inches in a configuration that is useable in the blade manufacturing area. The systems ability to input design data from CAD data bases and output measurement data in a CAD compatible data format is discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, Katherine L.; Judenhofer, Martin S.; Cherry, Simon R.

In preclinical single-photon emission computed tomography (SPECT) system development the primary objective has been to improve spatial resolution by using novel parallel-hole or multi-pinhole collimator geometries. Furthermore, such high-resolution systems have relatively poor sensitivity (typically 0.01% to 0.1%). In contrast, a system that does not use collimators can achieve very high-sensitivity. Here we present a high-sensitivity un-collimated detector single-photon imaging (UCD-SPI) system for the imaging of both small animals and plants. This scanner consists of two thin, closely spaced, pixelated scintillator detectors that use NaI(Tl), CsI(Na), or BGO. The performance of the system has been characterized by measuring sensitivity, spatialmore » resolution, linearity, detection limits, and uniformity. With 99mTc (140 keV) at the center of the field of view (20 mm scintillator separation), the sensitivity was measured to be 31.8% using the NaI(Tl) detectors and 40.2% with CsI(Na). The best spatial resolution (FWHM when the image formed as the geometric mean of the two detector heads, 20 mm scintillator separation) was 19.0 mm for NaI(Tl) and 11.9 mm for CsI(Na) at 140 keV, and 19.5 mm for BGO at 1116 keV, which is somewhat degraded compared to the cm-scale resolution obtained with only one detector head and a close source. The quantitative accuracy of the system’s linearity is better than 2% with detection down to activity levels of 100 nCi. Two in vivo animal studies (a renal scan using 99mTc MAG-3 and a thyroid scan with 123I) and one plant study (a 99mTcO 4- xylem transport study) highlight the unique capabilities of this UCD-SPI system. From the renal scan, we observe approximately a one thousand-fold increase in sensitivity compared to the Siemens Inveon SPECT/CT scanner. In conclusion, UCD-SPI is useful for many imaging tasks that do not require excellent spatial resolution, such as high-throughput screening applications, simple radiotracer uptake studies in tumor xenografts, dynamic studies where very good temporal resolution is critical, or in planta imaging of radioisotopes at low concentrations.« less

3D reconstruction from non-uniform point clouds via local hierarchical clustering

NASA Astrophysics Data System (ADS)

Yang, Jiaqi; Li, Ruibo; Xiao, Yang; Cao, Zhiguo

2017-07-01

Raw scanned 3D point clouds are usually irregularly distributed due to the essential shortcomings of laser sensors, which therefore poses a great challenge for high-quality 3D surface reconstruction. This paper tackles this problem by proposing a local hierarchical clustering (LHC) method to improve the consistency of point distribution. Specifically, LHC consists of two steps: 1) adaptive octree-based decomposition of 3D space, and 2) hierarchical clustering. The former aims at reducing the computational complexity and the latter transforms the non-uniform point set into uniform one. Experimental results on real-world scanned point clouds validate the effectiveness of our method from both qualitative and quantitative aspects.

A new spherical scanning system for infrared reflectography of paintings

NASA Astrophysics Data System (ADS)

Gargano, M.; Cavaliere, F.; Viganò, D.; Galli, A.; Ludwig, N.

2017-03-01

Infrared reflectography is an imaging technique used to visualize the underdrawings of ancient paintings; it relies on the fact that most pigment layers are quite transparent to infrared radiation in the spectral band between 0.8 μm and 2.5 μm. InGaAs sensor cameras are nowadays the most used devices to visualize the underdrawings but due to the small size of the detectors, these cameras are usually mounted on scanning systems to record high resolution reflectograms. This work describes a portable scanning system prototype based on a peculiar spherical scanning system built through a light weight and low cost motorized head. The motorized head was built with the purpose of allowing the refocusing adjustment needed to compensate the variable camera-painting distance during the rotation of the camera. The prototype has been tested first in laboratory and then in-situ for the Giotto panel "God the Father with Angels" with a 256 pixel per inch resolution. The system performance is comparable with that of other reflectographic devices with the advantage of extending the scanned area up to 1 m × 1 m, with a 40 min scanning time. The present configuration can be easily modified to increase the resolution up to 560 pixels per inch or to extend the scanned area up to 2 m × 2 m.

Automated planning of MRI scans of knee joints

NASA Astrophysics Data System (ADS)

Bystrov, Daniel; Pekar, Vladimir; Young, Stewart; Dries, Sebastian P. M.; Heese, Harald S.; van Muiswinkel, Arianne M.

2007-03-01

A novel and robust method for automatic scan planning of MRI examinations of knee joints is presented. Clinical knee examinations require acquisition of a 'scout' image, in which the operator manually specifies the scan volume orientations (off-centres, angulations, field-of-view) for the subsequent diagnostic scans. This planning task is time-consuming and requires skilled operators. The proposed automated planning system determines orientations for the diagnostic scan by using a set of anatomical landmarks derived by adapting active shape models of the femur, patella and tibia to the acquired scout images. The expert knowledge required to position scan geometries is learned from previous manually planned scans, allowing individual preferences to be taken into account. The system is able to automatically discriminate between left and right knees. This allows to use and merge training data from both left and right knees, and to automatically transform all learned scan geometries to the side for which a plan is required, providing a convenient integration of the automated scan planning system in the clinical routine. Assessment of the method on the basis of 88 images from 31 different individuals, exhibiting strong anatomical and positional variability demonstrates success, robustness and efficiency of all parts of the proposed approach, which thus has the potential to significantly improve the clinical workflow.

A Scanning scheimpflug lidar system developed for urban pollution monitoring

NASA Astrophysics Data System (ADS)

Yang, Yang; Guan, Peng; Mei, Liang

2018-04-01

A scanning Scheimpflug lidar system based on the Scheimpflug principle has been developed by employing a high power multimode 808 nm laser diode and a highly integrated CMOS sensor in Dalian University of Technology, Dalian, Northern China. Atmospheric scanning measurements in urban area were performed for the studies of particle emission sources.

Environmental Scan of BC Post-Secondary Admissions: 2009

ERIC Educational Resources Information Center

Heath, Nick

2009-01-01

In 2008, British Columbia Council on Admissions and Transfer (BCCAT) commissioned an environmental scan on the possible need for system-wide work on institutional admissions processes and practices. This scan is intended to seek system input and to provide guidance on the choice of research projects and other related work in the coming year. This…

Development of NIRS pencil beam scanning system for carbon ion radiotherapy

NASA Astrophysics Data System (ADS)

Furukawa, T.; Hara, Y.; Mizushima, K.; Saotome, N.; Tansho, R.; Saraya, Y.; Inaniwa, T.; Mori, S.; Iwata, Y.; Shirai, T.; Noda, K.

2017-09-01

At Heavy Ion Medical Accelerator in Chiba (HIMAC) in National Institute of Radiological Sciences (NIRS), more than 9000 patients have been successfully treated by carbon ion beams since 1994. The successful results of treatments have led us to construct a new treatment facility equipped with a three-dimensional pencil beam scanning irradiation system, which is one of sophisticated techniques for cancer therapy with high energetic ion beam. This new facility comprises two treatment rooms having fixed beam lines and one treatment room having rotating gantry line. The challenge of this project is to realize treatment of a moving target by scanning irradiation. Thus, to realize this, the development of the fast scanning system is one of the most important issues in this project. After intense commissioning and quality assurance tests, the treatment with scanned ion beam was started in May 2011. After treatment of static target starts, we have developed related technologies. As a result, we can start treatment of moving target and treatment without range shifter plates since 2015. In this paper, the developments of the scanning irradiation system are described.

Survey of current practice in clinical transvaginal ultrasound scanning in the UK

PubMed Central

Shaw, Adam; Lees, Christoph

2015-01-01

During transvaginal ultrasound scanning, the fetus and other sensitive tissues are placed close to the transducer. Heating of these tissues occurs by direct conduction from the transducer and by absorption of ultrasound in the tissue. The extent of any heating will depend on the equipment and settings used, the duration of the scan, imaging modes and other aspects of scanning practice. To ensure that scans are performed with minimum risk, staff should have an appropriate knowledge of safety and follow guidelines issued by professional bodies. An online survey aiming to document current practice in transvaginal ultrasound in the UK was created and distributed to individuals performing this type of scanning. The survey posed questions about the respondents, the departments where scans were performed, the equipment used, knowledge of ultrasound safety, scanning practice and the frequency, duration and mode of transvaginal ultrasound scans for gynaecology, obstetrics and fertility applications. In all, 294 responses were obtained, mostly from sonographers (94%). From the analysis of the responses, it was clear that there was a good understanding of the general meaning of thermal and mechanical index and high awareness of guidelines issued by professional bodies. However, 40% of respondents stated that they rarely or never monitor Thermal or Mechanical indices during scanning. Scanning practice was consistent in terms of the duration of scans, scan protocols followed and use of imaging modes. The results highlight the importance of continued ultrasound safety training and promotion of safety guidelines to users. PMID:27433250

Note: Development of a wideband amplifier for cryogenic scanning tunneling microscopy.

PubMed

Zhang, Chao; Jeon, Hoyeon; Oh, Myungchul; Lee, Minjun; Kim, Sungmin; Yi, Sunwouk; Lee, Hanho; Zoh, Inhae; Yoo, Yongchan; Kuk, Young

2017-06-01

A wideband cryogenic amplifier has been developed for low temperature scanning tunneling microscopy. The amplifier consisting of a wideband complementary metal oxide semiconductor field effect transistors operational amplifier together with a feedback resistor of 100 kΩ and a capacitor is mounted within a 4 K Dewar. This amplifier has a wide bandwidth and is successfully applied to scanning tunneling microscopy applications at low temperatures down to ∼7 K. The quality of the designed amplifier is validated by high resolution imaging. More importantly, the amplifier has also proved to be capable of performing scanning tunneling spectroscopy measurements, showing the detection of the Shockley surface state of the Au(111) surface and the superconducting gap of Nb(110).

Note: Development of a wideband amplifier for cryogenic scanning tunneling microscopy

NASA Astrophysics Data System (ADS)

Zhang, Chao; Jeon, Hoyeon; Oh, Myungchul; Lee, Minjun; Kim, Sungmin; Yi, Sunwouk; Lee, Hanho; Zoh, Inhae; Yoo, Yongchan; Kuk, Young

2017-06-01

A wideband cryogenic amplifier has been developed for low temperature scanning tunneling microscopy. The amplifier consisting of a wideband complementary metal oxide semiconductor field effect transistors operational amplifier together with a feedback resistor of 100 kΩ and a capacitor is mounted within a 4 K Dewar. This amplifier has a wide bandwidth and is successfully applied to scanning tunneling microscopy applications at low temperatures down to ˜7 K. The quality of the designed amplifier is validated by high resolution imaging. More importantly, the amplifier has also proved to be capable of performing scanning tunneling spectroscopy measurements, showing the detection of the Shockley surface state of the Au(111) surface and the superconducting gap of Nb(110).

Characterization of photon-counting multislit breast tomosynthesis.

PubMed

Berggren, Karl; Cederström, Björn; Lundqvist, Mats; Fredenberg, Erik

2018-02-01

It has been shown that breast tomosynthesis may improve sensitivity and specificity compared to two-dimensional mammography, resulting in increased detection-rate of cancers or lowered call-back rates. The purpose of this study is to characterize a spectral photon-counting multislit breast tomosynthesis system that is able to do single-scan spectral imaging with multiple collimated x-ray beams. The system differs in many aspects compared to conventional tomosynthesis using energy-integrating flat-panel detectors. The investigated system was a prototype consisting of a dual-threshold photon-counting detector with 21 collimated line detectors scanning across the compressed breast. A review of the system is done in terms of detector, acquisition geometry, and reconstruction methods. Three reconstruction methods were used, simple back-projection, filtered back-projection and an iterative algebraic reconstruction technique. The image quality was evaluated by measuring the modulation transfer-function (MTF), normalized noise-power spectrum, detective quantum-efficiency (DQE), and artifact spread-function (ASF) on reconstructed spectral tomosynthesis images for a total-energy bin (defined by a low-energy threshold calibrated to remove electronic noise) and for a high-energy bin (with a threshold calibrated to split the spectrum in roughly equal parts). Acquisition was performed using a 29 kVp W/Al x-ray spectrum at a 0.24 mGy exposure. The difference in MTF between the two energy bins was negligible, that is, there was no energy dependence on resolution. The MTF dropped to 50% at 1.5 lp/mm to 2.3 lp/mm in the scan direction and 2.4 lp/mm to 3.3 lp/mm in the slit direction, depending on the reconstruction method. The full width at half maximum of the ASF was found to range from 13.8 mm to 18.0 mm for the different reconstruction methods. The zero-frequency DQE of the system was found to be 0.72. The fraction of counts in the high-energy bin was measured to be 59% of the total detected spectrum. Scantimes ranged from 4 s to 16.5 s depending on voltage and current settings. The characterized system generates spectral tomosynthesis images with a dual-energy photon-counting detector. Measurements show a high DQE, enabling high image quality at a low dose, which is beneficial for low-dose applications such as screening. The single-scan spectral images open up for applications such as quantitative material decomposition and contrast-enhanced tomosynthesis. © 2017 American Association of Physicists in Medicine.

Managing Strategic Change: An Executive Overview

DTIC Science & Technology

2003-06-01

strategic plan and policies based on the results of the environmental scan in comparison with the strengths and weaknesses of the organization...DISCLAIMER The views expressed in this report are those of the author and do not necessarily reflect official policy or position of...management echelon and has a time horizon consistent with the scanning abilities of the organization and set at the risk level (comfort zone) that

SU-E-I-15: Comparison of Radiation Dose for Radiography and EOS in Adolescent Scoliosis Patients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schueler, B; Walz-Flannigan, A

Purpose: To estimate patient radiation dose for whole spine imaging using EOS, a new biplanar slot-scanning radiographic system and compare with standard scoliosis radiography. Methods: The EOS imaging system (EOS Imaging, Paris, France) consists of two orthogonal x-ray fan beams which simultaneously acquire frontal and lateral projection images of a standing patient. The patient entrance skin air kerma was measured for each projection image using manufacturer-recommended exposure parameters for spine imaging. Organ and effective doses were estimated using a commercially-available Monte Carlo simulation program (PCXMC, STUK, Radiation and Nuclear Safety Authority, Helsinki, Finland) for a 15 year old mathematical phantommore » model. These results were compared to organ and effective dose estimated for scoliosis radiography using computed radiography (CR) with standard exposure parameters obtained from a survey of pediatric radiographic projections. Results: The entrance skin air kerma for EOS was found to be 0.18 mGy and 0.33 mGy for posterior-anterior (PA) and lateral projections, respectively. This compares to 0.76 mGy and 1.4 mGy for CR, PA and lateral projections. Effective dose for EOS (PA and lateral projections combined) is 0.19 mSv compared to 0.51 mSv for CR. Conclusion: The EOS slot-scanning radiographic system allows for reduced patient radiation dose in scoliosis patients as compared to standard CR radiography.« less

MEMS compatible illumination and imaging micro-optical systems

NASA Astrophysics Data System (ADS)

Bräuer, A.; Dannberg, P.; Duparré, J.; Höfer, B.; Schreiber, P.; Scholles, M.

2007-01-01

The development of new MOEMS demands for cooperation between researchers in micromechanics, optoelectronics and microoptics at a very early state. Additionally, microoptical technologies being compatible with structured silicon have to be developed. The microoptical technologies used for two silicon based microsystems are described in the paper. First, a very small scanning laser projector with a volume of less than 2 cm 3, which operates with a directly modulated lasers collimated with a microlens, is shown. The laser radiation illuminates a 2D-MEMS scanning mirror. The optical design is optimized for high resolution (VGA). Thermomechanical stability is realized by design and using a structured ceramics motherboard. Secondly, an ultrathin CMOS-camera having an insect inspired imaging system has been realized. It is the first experimental realization of an artificial compound eye. Micro-optical design principles and technology is used. The overall thickness of the imaging system is only 320 μm, the diagonal field of view is 21°, and the f-number is 2.6. The monolithic device consists of an UV-replicated microlens array upon a thin silica substrate with a pinhole array in a metal layer on the back side. The pitch of the pinholes differs from that of the lens array to provide individual viewing angle for each channel. The imaging chip is directly glued to a CMOS sensor with adapted pitch. The whole camera is less than 1mm thick. New packaging methods for these systems are under development.

Cellular organisation and functions of the olfactory epithelium of pearl spot Etroplus suratensis (Bloch): a light and scanning electron microscopic study.

PubMed

Ghosh, S K; Chakrabarti, P

2010-08-01

The cellular organisation of the olfactory rosettes of Etroplus suratensis was studied by light and scanning electron microscopy. The oval shaped olfactory rosette of the fish consists of 12 lamellae radiating from a central raphe. The olfactory lamellae are comprised of restricted areas of sensory epithelium and broad areas of non-sensory epithelium in the apical, middle, and basal regions. The sensory epithelium contains three types of receptor cells: microvillus, ciliated, and rod cells, as well as labyrinth cells and supporting cells. The non-sensory epithelium consists of stratified epithelial and mucous cells. The transitional region between the sensory and non-sensory epithelium consists of ciliated receptor cells, mucous cells, and stratified epithelial cells. The different cells on the olfactory epithelium were discussed regarding the functional significance of the fish concerned.

Method for visualization and presentation of priceless old prints based on precise 3D scan

NASA Astrophysics Data System (ADS)

Bunsch, Eryk; Sitnik, Robert

2014-02-01

Graphic prints and manuscripts constitute main part of the cultural heritage objects created by the most of the known civilizations. Their presentation was always a problem due to their high sensitivity to light and changes of external conditions (temperature, humidity). Today it is possible to use an advanced digitalization techniques for documentation and visualization of mentioned objects. In the situation when presentation of the original heritage object is impossible, there is a need to develop a method allowing documentation and then presentation to the audience of all the aesthetical features of the object. During the course of the project scans of several pages of one of the most valuable books in collection of Museum of Warsaw Archdiocese were performed. The book known as "Great Dürer Trilogy" consists of three series of woodcuts by the Albrecht Dürer. The measurement system used consists of a custom designed, structured light-based, high-resolution measurement head with automated digitization system mounted on the industrial robot. This device was custom built to meet conservators' requirements, especially the lack of ultraviolet or infrared radiation emission in the direction of measured object. Documentation of one page from the book requires about 380 directional measurements which constitute about 3 billion sample points. The distance between the points in the cloud is 20 μm. Provided that the measurement with MSD (measurement sampling density) of 2500 points makes it possible to show to the publicity the spatial structure of this graphics print. An important aspect is the complexity of the software environment created for data processing, in which massive data sets can be automatically processed and visualized. Very important advantage of the software which is using directly clouds of points is the possibility to manipulate freely virtual light source.

Monitoring of volcanic emissions for risk assessment at Popocatépetl volcano (Mexico)

NASA Astrophysics Data System (ADS)

Delgado, Hugo; Campion, Robin; Fickel, Matthias; Cortés Ramos, Jorge; Alvarez Nieves, José Manuel; Taquet, Noemi; Grutter, Michel; Osiris García Gómez, Israel; Darío Sierra Mondragón, Rubén; Meza Hernández, Israel

2015-04-01

In January 2014, the Mexican Agency FOPREDEN (Natural Disaster Prevention Fund) accepted to fund a project to renew, upgrade and complement the gas monitoring facilities. The UNAM-CENAPRED (National Center for Disaster Prevention) gas monitoring system currently consists of: • A COSPEC instrument and two mini-DOAS used for mobile traverse measurements • An SO2 camera used for punctual campaign • A network of three permanent scanning mini-DOAS (NOVAC type 1 instrument) and one permanent mini-DOAS (NOVAC type II, currently under repair). The activity planed in the framework of the new project, of which several of them are already successfully implemented, include: • Completely refurbished permanent scanning mini-DOAS network consisting of four stations and the punctual deployment of three RADES (Rapid Deployment System) for assessing plume geometry and chemistry or for responding to emergency situations. • Prolongation of the mobile traverse measurements in order to continuously update the 20 years-long SO2 flux database obtained with the COSPEC, now coupled with a mobile DOAS for redundancy. • The development and installation of a permanent SO2 camera, for monitoring in real time the short timescale variations of the SO2 emissions. • The installation of two permanent FTIR spectrometers, one measuring the plume thermal emissions and the other measuring with the solar occultation geometry, for frequent measurements of molecular ratio between SO2, HCl, HF and SiF4 • The exploitation in near-real time of the satellite imagery (OMI, MODIS and ASTER) available for the volcano. A special attention will be paid to increase the reliability and graphical representation of these data stream in order to facilitate their use for decision-making by the civil protection authority in charge of the volcano.

A breast-specific, negligible-dose scatter correction technique for dedicated cone-beam breast CT: a physics-based approach to improve Hounsfield Unit accuracy

NASA Astrophysics Data System (ADS)

Yang, Kai; Burkett, George, Jr.; Boone, John M.

2014-11-01

The purpose of this research was to develop a method to correct the cupping artifact caused from x-ray scattering and to achieve consistent Hounsfield Unit (HU) values of breast tissues for a dedicated breast CT (bCT) system. The use of a beam passing array (BPA) composed of parallel-holes has been previously proposed for scatter correction in various imaging applications. In this study, we first verified the efficacy and accuracy using BPA to measure the scatter signal on a cone-beam bCT system. A systematic scatter correction approach was then developed by modeling the scatter-to-primary ratio (SPR) in projection images acquired with and without BPA. To quantitatively evaluate the improved accuracy of HU values, different breast tissue-equivalent phantoms were scanned and radially averaged HU profiles through reconstructed planes were evaluated. The dependency of the correction method on object size and number of projections was studied. A simplified application of the proposed method on five clinical patient scans was performed to demonstrate efficacy. For the typical 10-18 cm breast diameters seen in the bCT application, the proposed method can effectively correct for the cupping artifact and reduce the variation of HU values of breast equivalent material from 150 to 40 HU. The measured HU values of 100% glandular tissue, 50/50 glandular/adipose tissue, and 100% adipose tissue were approximately 46, -35, and -94, respectively. It was found that only six BPA projections were necessary to accurately implement this method, and the additional dose requirement is less than 1% of the exam dose. The proposed method can effectively correct for the cupping artifact caused from x-ray scattering and retain consistent HU values of breast tissues.

An open library of CT patient projection data

NASA Astrophysics Data System (ADS)

Chen, Baiyu; Leng, Shuai; Yu, Lifeng; Holmes, David; Fletcher, Joel; McCollough, Cynthia

2016-03-01

Lack of access to projection data from patient CT scans is a major limitation for development and validation of new reconstruction algorithms. To meet this critical need, we are building a library of CT patient projection data in an open and vendor-neutral format, DICOM-CT-PD, which is an extended DICOM format that contains sinogram data, acquisition geometry, patient information, and pathology identification. The library consists of scans of various types, including head scans, chest scans, abdomen scans, electrocardiogram (ECG)-gated scans, and dual-energy scans. For each scan, three types of data are provided, including DICOM-CT-PD projection data at various dose levels, reconstructed CT images, and a free-form text file. Several instructional documents are provided to help the users extract information from DICOM-CT-PD files, including a dictionary file for the DICOM-CT-PD format, a DICOM-CT-PD reader, and a user manual. Radiologist detection performance based on the reconstructed CT images is also provided. So far 328 head cases, 228 chest cases, and 228 abdomen cases have been collected for potential inclusion. The final library will include a selection of 50 head, chest, and abdomen scans each from at least two different manufacturers, and a few ECG-gated scans and dual-source, dual-energy scans. It will be freely available to academic researchers, and is expected to greatly facilitate the development and validation of CT reconstruction algorithms.

The Scanning Process: Getting Started.

ERIC Educational Resources Information Center

Renfro, William L.; Morrison, James L.

1983-01-01

Scanning the external environment will become more essential to colleges in the coming decade. Developing an environmental scanning system can identify important emerging issues that may constitute either threats or opportunities. The organizational features of a mature scanning process are described. (MLW)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, C; Seduk, J; Yang, T

Purpose: A prototype actives scanning beam delivery system was designed, manufactured and installed as a part of the Korea Heavy Ion Medical Accelerator Project. The prototype system includes the most components for steering, modulating, detecting incident beam to patient. The system was installed in MC-50 cyclotron beam line and tested to extract the normal operation conditions. Methods: The commissioning process was completed by using 45 MeV of proton beam. To measure the beam position accuracy along the scanning magnet power supply current, 25 different spots were scanning and measured. The scanning results on GaF film were compared with the irradiationmore » plan. Also, the beam size variation and the intensity reduction using range shifter were measured and analyzed. The results will be used for creating a conversion factors for asymmetric behavior of scanning magnets and a dose compensation factor for longitudinal direction. Results: The results show asymmetry operations on both scanning × and y magnet. In case of scanning magnet × operation, the current to position conversion factors were measured 1.69 mm/A for positive direction and 1.74 mm/A for negative direction. The scanning magnet y operation shows 1.38mm/A and 1.48 mm/A for both directions. The size of incoming beam which was 18 mm as sigma becomes larger up to 55 mm as sigma while using 10 mm of the range shifter plate. As the beam size becomes large, the maximum intensity of the was decreased. In case of using 10 mm of range shifter, the maximum intensity was only 52% compared with no range shifter insertion. Conclusion: For the appropriate operation of the prototype active scanning system, the commissioning process were performed to measure the beam characteristics variation. The obtained results would be applied on the irradiation planning software for more precise dose delivery using the active scanning system.« less

Device-independent color scanning

NASA Astrophysics Data System (ADS)

Burger, Rudolph E.

1993-08-01

Color calibration technology is being incorporated into both Apple and Microsoft's operating systems. These color savvy operating systems will produce a market pull towards 'smart color' scanners and printers which, in turn, will lead towards a distributed architecture for color management systems (CMS). Today's desktop scanners produce red-green-blue color signals that do not accurately describe the color of the object being scanned. Future scanners will be self-calibrating and communicate their own 'device profile' to the operating system based CMS. This paper describes some of the key technologies required for this next generation of smart color scanners. Topics covered include a comparison of colorimetric and conventional scanning technologies, and the impact of metamerism, dye fluorescence and chromatic adaptation on device independent color scanning.

A Novel Concept for Observing Land-Surface-Atmosphere Feedback Based on a Synergy of Scanning Lidar Systems

NASA Astrophysics Data System (ADS)

Wulfmeyer, V.; Turner, D. D.; Mauder, M.; Behrendt, A.; Ingwersen, J.; Streck, T.

2015-12-01

Improved simulations of land-surface-atmosphere interaction are fundamental for improving weather forecast and climate models. This requires observations of 2D fields of surface fluxes and the 3D structure of the atmospheric boundary layer simultaneously. A novel strategy is introduced for studying land-surface exchange and entrainment processes in the convective boundary layer (CBL) over complex terrain by means of a new generation of remote sensing systems. The sensor synergy consists of scanning Doppler lidar (DL), water-vapor differential absorption lidar (WVDIAL), and temperature rotational Raman lidar (TRRL) systems supported by surface in-situ measurements. The 2D measurements of surface fluxes are realized by the operation of a DL, a WVDIAL, and a TRRL along the same line-of-sight (LOS) in a range-height-indicator (RHI) mode whereas the other DL is performing a series of cross track RHI scans along this LOS. This new setup enables us to determine the friction velocity as well as surface sensible and latent heat fluxes by closing the complete set of Monin-Obukhov similarity relationships under a variety of surface layer stability conditions and different land cover and soil properties. As this closure is performed at all DL crossing points along the LOS, this is a strategy towards a 2D mapping of surface fluxes entirely based on remote sensing systems. Further details are presented at the conference. The second configuration is the simultaneous vertical profiling of vertical wind, humidity and temperature by DL, WVDIAL and TRRL so that latent heat and sensible heat flux profiles as well as a variety of different turbulent moments can be measured in the CBL. Consequently, by alternating of RHI scanning and vertical pointing modes, entrainment fluxes and surface fluxes can be measured almost simultaneously. This novel strategy has been realized for the first time during the Surface Atmospheric Boundary Layer Exchange (SABLE) campaign in the Kraichgau region, north of the Black Forest low mountain region, in Southern Germany in August 2014 (see https://klimawandel.uni-hohenheim.de/start?&L=1). A further refined design of this experiment is planned at the Atmospheric Radiation Measurement Program (ARM) Southern Great Plains (SGP) site in summer 2016.