Serosurveillance of Scrub Typhus in Small Mammals Collected from Military Training Sites near the DMZ, Northern Gyeonggi-do, Korea, and Analysis of the Relative Abundance of Chiggers from Mammals Examined

DTIC Science & Technology

2010-09-01

Korean J Paras/to/. Vol. 48, No. 3: 237-243, September 2010 DOl: JO.J3471kjp.2010.48.J.237 Serosurveillance of Scrub Typhus in Small Mammals...65th Medical BrigadeAJSAMEDDAC-Korea, Unit# 15281, APO AP 96205-5281, USA Abstract: Comprehensive quarterly serosurveillance on scrub typhus in small...rarely observed (prevalence < 1 0%). In contrast to previous surveys, higher chigger indices of the primary scrub typhus vectors, L. pallidum (165.4

Geo-Coding for the Mapping of Documents and Social Media Messages

DTIC Science & Technology

2013-08-22

O.L. (2007). UBC-ALM: Combining KNN with SVD for WSD. Proceedings of the 4th International Workshop on Semantic Evaluations (SemEval-2007), Prague...and Yarowsky, D. (1992). One sense per discourse. In Proceedings of the 4th DARPA Speech and Natural Language Workshop. pp. 233-237, 1992. Retrieved...Part-of- Speech Tagging for Twitter: Annotation, Features, and Experiments. Proceedings of the Annual Meeting of the Association for Computational

The Effect of Scheduling Models for Introductory Algebra on 9th-Grade Students, Test Scores and Grades

ERIC Educational Resources Information Center

O'Hanlon, Angela L.

2011-01-01

The purpose of the study was to determine the effect of pacing and scheduling of algebra coursework on assigned 9th-grade students who traditionally would qualify for pre-algebra instruction and same course 9th-grade students who traditionally would qualify for standard algebra instruction. Students were selected based on completion of first-year…

Scheduled physical activity is associated with better academic performance in Chilean school-age children.

PubMed

Burrows, Raquel; Correa-Burrows, Paulina; Orellana, Yasna; Almagiá, Atilio; Lizana, Pablo; Ivanovic, Daniza

2014-11-01

This study was carried out to examine the association between systematic physical activity and academic performance in school kids after controlling for potential sociodemographic and educational confounders. In a random sample of 1271 students from urban Santiago, attending 5th and 9th grade, who took the 2009 System for the Assessment of Educational Quality (SIMCE) tests, we measured physical activity habits, anthropometric characteristics, and socioeconomic status. Academic performance was measured by the standardized SIMCE tests. Logistic regressions assessed the relationship between the allocation of time to weekly scheduled exercise, potential confounding factors, and individual academic performance. About 80% of students reported less than 2 hours of weekly scheduled exercise, while 10.6% and 10.2% reported 2 to 4 hours/week and more than 4 hours/week, respectively. Devoting more than 4 hours/week to scheduled exercise significantly increased (P < .01) the odds of having SIMCE composite z-scores ≥ 50th percentile (OR: 2.3, 95% CI: 1.4 to 3.6) and ≥ 75th percentile (OR: 2.1, 95% CI: 1.3-3.3). Better academic performance was associated with a higher allocation of time to scheduled exercise in school-age children.

Alternative scheduling models and their effect on science achievement at the high school level

NASA Astrophysics Data System (ADS)

Dostal, Jay Roland

This study will evaluate alternative scheduling methods implemented in secondary level schools. Students were selected based on parent selection of programs. Traditional scheduling involves numerous academic subjects with small increments of time in each class and block scheduling focuses on fewer academic subjects and more instructional time. This study will compare office referral numbers, absence frequency, and Essential Learner Outcome (ELO) science strand scores in the 8th-grade (pretest) to the same students office referrals, absence frequency, and ELO science strand scores in the 11th-grade (posttest) between Seven Period Traditional Scheduling (SPTS) and Four Period Block Scheduling (FPBS) in the hopes that no matter what schedule students are a part of, the achievement results will be similar. (Study participants had completed both grade level ELO assessments and were continuously enrolled in one high school through their junior year.

MPLMs viewed in SSPF

NASA Technical Reports Server (NTRS)

2000-01-01

In the Space Station Processing Facility sits Raffaello, one of two Multi-Purpose Logistics Modules (MPLMs) built by Italy for the International Space Station. Raffaello is scheduled on mission STS-100, the 9th flight to the Space Station in 2001. The other MPLM is Leonardo, scheduled on an earlier mission, STS-102, the 8th flight early in 2001.

MPLMs viewed in SSPF

NASA Technical Reports Server (NTRS)

2000-01-01

In the Space Station Processing Facility sit Raffaello (left) and Leonardo (right), two Multi-Purpose Logistics Modules (MPLMs) built by Italy for the International Space Station. Leonardo is scheduled on mission STS-102, the 8th flight to the Space Station early in 2001. Raffaello is scheduled on mission STS-100, the 9th flight to the Space Station in 2001.

MPLMs viewed in SSPF

NASA Technical Reports Server (NTRS)

2000-01-01

In the Space Station Processing Facility sit Leonardo (left) and Raffaello (right), two Multi-Purpose Logistics Modules (MPLMs) built by Italy for the International Space Station. Raffaello is scheduled on mission STS-100, the 9th flight to the Space Station in 2001. The other MPLM is Leonardo, scheduled on an earlier mission, STS-102, the 8th flight early in 2001.

Distinguishing Fissile From Non-Fissile Materials Using Linearly Polarized Gamma Rays

NASA Astrophysics Data System (ADS)

Mueller, J. M.; Ahmed, M. W.; Karwowski, H. J.; Myers, L. S.; Sikora, M. H.; Weller, H. R.; Zimmerman, W. R.; Randrup, J.; Vogt, R.

2014-03-01

Photofission of 232Th, 233 , 235 , 238U, 237Np, and 239,240Pu was induced by nearly 100% linearly polarized, high intensity (~107 γs per second), and nearly-monoenergetic γ-ray beams of energies between 5.3 and 7.6 MeV at the High Intensity γ-ray Source (HI γS). An array of 12-18 liquid scintillating detectors was used to measure prompt fission neutron yields. The ratio of prompt fission neutron yields parallel to the plane of beam polarization to the yields perpendicular to this plane was measured as a function of beam and neutron energy. A ratio near unity was found for 233,235U, 237Np, and 239Pu while a significant ratio (~1.5-3) was found for 232Th, 238U, and 240Pu. This large difference could be used to distinguish fissile isotopes (such as 233,235U and 239Pu) from non-fissile isotopes (such as 232Th, 238U, and 240Pu). The measured ratios agree with the results of a fission calculation (FREYA) which used with previously measured photofission fragment angular distributions as input. Partially supported by DHS (2010-DN-077-ARI046-02), DOE (DE-AC52-07NA27344 and DE-AC02-05CH11231), and the DOE Office of Science Graduate Fellowship Program (DOE SCGF).

The use of a biologic topical haemostatic agent (TachoSil(®)) for the prevention of postoperative bleeding in patients on antithrombotic therapy undergoing thyroid surgery: A randomised controlled pilot trial.

PubMed

Erdas, Enrico; Medas, Fabio; Podda, Francesco; Furcas, Silvia; Pisano, Giuseppe; Nicolosi, Angelo; Calò, Pietro Giorgio

2015-08-01

Anticoagulants and antiplatelet agents are well-known risk factors for post-operative bleeding. The aim of this prospective, randomized pilot study was to evaluate the effectiveness of a topical haemostatic agent, namely TachoSil, for the prevention of postoperative bleeding in patients on antithrombotic therapy undergoing thyroidectomy. Perioperative management and some distinctive aspects of cervical haematomas were also discussed. Between January 2012 and May 2014, all patients taking vitamin K antagonists (VKAs) or acetyl salicylic acid (ASA) scheduled for total thyroidectomy were enrolled and randomly allocated to group 1 (standard haemostasis) and group 2 (standard haemostasis + TachoSil). Antithrombotic drugs were always suspended prior to surgery and, when indicated, replaced by bridging anticoagulation with low-molecular-weight heparin. The primary endpoint was the incidence of postoperative cervical haematomas. A total of 70 patients were included in the study, representing 8.5% (70/820) of all patients who underwent thyroidectomies in the same period. The overall rate of post-operative cervical haematoma was 7.1% (5/70) and reached 14.8% (4/27) in patients on VKA therapy. All but one occurred more than 24 h after surgery (32nd hour, 8th, 10th, and 13th days). Group 1 (37 patients) and group 2 (33 patients) were well-matched according to clinical and demographic features. Postoperative haematoma was observed in 2/37 patients (5.4%) recruited in the Group 1 and 3/33 patients (9.1%) recruited in the Group 2 (P = 0.661). Patients taking antithrombotic drugs represent a major problem in thyroid surgery. The incidence of bleeding after thyroidectomy is significantly high and the use of TachoSil do not seem effective in preventing its occurrence. However, larger multicenter study is needed to confirm these results. Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

MPLMs viewed in SSPF

NASA Technical Reports Server (NTRS)

2000-01-01

The Multi-Purpose Logistics Module (MPLM) Leonardo, seen here, is one of two in the Space Station Processing Facility. The other is named Raffaello. Both MPLMs are components built by Italy for the International Space Station. Leonardo is scheduled on mission STS-102, the 8th flight to the Space Station early in 2001. Raffaello is scheduled on mission STS-100, the 9th flight, later in 2001.

MPLMs viewed in SSPF

NASA Technical Reports Server (NTRS)

2000-01-01

The Multi-Purpose Logistics Module (MPLM) Raffaello, seen here, is one of two in the Space Station Processing Facility. The other is named Leonardo. Both MPLMs are components built by Italy for the International Space Station. Raffaello is scheduled on mission STS-100, the 9th flight to the Space Station in 2001. Leonardo is scheduled on an earlier mission, STS-102, the 8th flight early in 2001.

Applying Syundz's Philosophical Concepts to Teaching Leadership in Higher Education and Lifelong Learning

ERIC Educational Resources Information Center

Ko, Hsin Chi

2016-01-01

Syundz (c. 314-237 BC), born in China during the Warring States Period, was a realist philosopher who contributed to the Hundred Schools of Thought, a period of cultural and philosophical development that flourished from the 6th century to 221 BC. Syundz commented on many ideas, particularly those of Confucius and Mencius, and a collection of…

KSC-97PC948

NASA Image and Video Library

1997-06-28

STS-94 Commander James D. Halsell, Jr., speaks to the media at the Shuttle Landing Facility after the crew arrived at Kennedy Space Center in preparation for the reflight of the Microgravity Science Laboratory-1 mission. Launch is scheduled for July 1, 1997, at 2:37 p.m. EDT. From left to right, the crew members are Payload Specialists Gregory T. Linteris and Roger K. Crouch; Mission Specialists Michael L. Gernhardt and Donald A. Thomas; Payload Commander Janice E. Voss; Pilot Susan Leigh Still and Commander James D. Halsell, Jr. One of the T-38 jets aboard which the crew arrived can be seen in the background. The laboratory was scheduled to fly again with the full complement of STS-83 experiments after that mission was cut short due to a faulty fuel cell. During the scheduled 16-day STS-94 mission, the experiments will be used to test some of the hardware, facilities and procedures that are planned for use on the International Space Station while the flight crew conducts combustion, protein crystal growth and materials processing experiments

Design and implementation of an experiment scheduling system for the ACTS satellite

NASA Technical Reports Server (NTRS)

Ringer, Mark J.

1994-01-01

The Advanced Communication Technology Satellite (ACTS) was launched on the 12th of September 1993 aboard STS-51. All events since that time have proceeded as planned with user operations commencing on December 6th, 1993. ACTS is a geosynchronous satellite designed to extend the state of the art in communication satellite design and is available to experimenters on a 'time/bandwidth available' basis. The ACTS satellite requires the advance scheduling of experimental activities based upon a complex set of resource, state, and activity constraints in order to ensure smooth operations. This paper describes the software system developed to schedule experiments for ACTS.

TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules.

PubMed

Liu, Qian; Sun, Jessica D; Wang, Jingli; Ahluwalia, Dharmendra; Baker, Amanda F; Cranmer, Lee D; Ferraro, Damien; Wang, Yan; Duan, Jian-Xin; Ammons, W Steve; Curd, John G; Matteucci, Mark D; Hart, Charles P

2012-06-01

Subregional hypoxia is a common feature of tumors and is recognized as a limiting factor for the success of radiotherapy and chemotherapy. TH-302, a hypoxia-activated prodrug selectively targeting hypoxic regions of solid tumors, delivers a cytotoxic warhead to the tumor, while maintaining relatively low systemic toxicity. The antitumor activity, different dosing sequences, and dosing regimens of TH-302 in combination with commonly used conventional chemotherapeutics were investigated in human tumor xenograft models. Seven chemotherapeutic drugs (docetaxel, cisplatin, pemetrexed, irinotecan, doxorubicin, gemcitabine, and temozolomide) were tested in combination with TH-302 in eleven human xenograft models, including non-small cell lung cancer (NSCLC), colon cancer, prostate cancer, fibrosarcoma, melanoma, and pancreatic cancer. The antitumor activity of docetaxel, cisplatin, pemetrexed, irinotecan, doxorubicin, gemcitabine, and temozolomide was increased when combined with TH-302 in nine out of eleven models tested. Administration of TH-302 2-8 h prior to the other chemotherapeutics yielded superior efficacy versus other sequences tested. Simultaneous administration of TH-302 and chemotherapeutics increased toxicity versus schedules with dosing separations. In a dosing optimization study, TH-302 administered daily at 50 mg/kg intraperitoneally for 5 days per week in the H460 NSCLC model showed the optimal response with minimal toxicity. TH-302 enhances the activity of a wide range of conventional anti-neoplastic agents in a broad panel of in vivo xenograft models. These data highlight in vivo effects of schedule and order of drug administration in regimen efficacy and toxicity and have relevance to the design of human regimens incorporating TH-302.

TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules

PubMed Central

Liu, Qian; Sun, Jessica D.; Wang, Jingli; Ahluwalia, Dharmendra; Baker, Amanda F.; Cranmer, Lee D.; Ferraro, Damien; Wang, Yan; Duan, Jian-Xin; Ammons, W. Steve; Curd, John G.; Matteucci, Mark D.

2014-01-01

Purpose Subregional hypoxia is a common feature of tumors and is recognized as a limiting factor for the success of radiotherapy and chemotherapy. TH-302, a hypoxia-activated prodrug selectively targeting hypoxic regions of solid tumors, delivers a cytotoxic warhead to the tumor, while maintaining relatively low systemic toxicity. The antitumor activity, different dosing sequences, and dosing regimens of TH-302 in combination with commonly used conventional chemotherapeutics were investigated in human tumor xenograft models. Methods Seven chemotherapeutic drugs (docetaxel, cisplatin, pemetrexed, irinotecan, doxorubicin, gemcitabine, and temozolomide) were tested in combination with TH-302 in eleven human xenograft models, including non-small cell lung cancer (NSCLC), colon cancer, prostate cancer, fibrosarcoma, melanoma, and pancreatic cancer. Results The antitumor activity of docetaxel, cisplatin, pemetrexed, irinotecan, doxorubicin, gemcitabine, and temozolomide was increased when combined with TH-302 in nine out of eleven models tested. Administration of TH-302 2–8 h prior to the other chemotherapeutics yielded superior efficacy versus other sequences tested. Simultaneous administration of TH-302 and chemotherapeutics increased toxicity versus schedules with dosing separations. In a dosing optimization study, TH-302 administered daily at 50 mg/kg intraperitoneally for 5 days per week in the H460 NSCLC model showed the optimal response with minimal toxicity. Conclusions TH-302 enhances the activity of a wide range of conventional anti-neoplastic agents in a broad panel of in vivo xenograft models. These data highlight in vivo effects of schedule and order of drug administration in regimen efficacy and toxicity and have relevance to the design of human regimens incorporating TH-302. PMID:22382881

Vehicle Test Procedure Driving Schedules

DOT National Transportation Integrated Search

1977-03-01

This report discusses the salient characteristics of driving schedules which are currently being used to determine automotive fuel economy, exhaust emissions, and component characteristics. The analyses discussed and the results reported highlight th...

A reevaluation of the infrared-radio correlation for spiral galaxies

NASA Technical Reports Server (NTRS)

Devereux, Nicholas A.; Eales, Stephen A.

1989-01-01

The infrared radio correlation has been reexamined for a sample of 237 optically bright spiral galaxies which range from 10 to the 8th to 10 to the 11th solar luminosities in far-infrared luminosity. The slope of the correlation is not unity. A simple model in which dust heating by both star formation and the interstellar radiation field contribute to the far-infrared luminosity can account for the nonunity slope. The model differs from previous two component models, however, in that the relative contribution of the two components is independent of far-infrared color temperature, but is dependent on the far-infrared luminosity.

Prolonged intervals during Mycobacterium tuberculosis subunit vaccine boosting contributes to eliciting immunity mediated by central memory-like T cells.

PubMed

Bai, Chunxiang; He, Juanjuan; Niu, Hongxia; Hu, Lina; Luo, Yanping; Liu, Xun; Peng, Liang; Zhu, Bingdong

2018-05-01

It is believed that central memory T cells (T CM ) provide long-term protection against tuberculosis (TB). However, the effects of TB subunit vaccine immunization schedule, especially the vaccination intervals, on T cell immune memory is still unclear. In this study, mice were immunized with fusion protein ESAT6-Ag85B-MPT64 (190-198)-Mtb8.4-Rv2626c (LT70) based subunit vaccine three times according to the following schedules: ① 0, 3rd and 6th week respectively (0-3-6w), ② 0, 4th and 12th week (0-4-12w), and ③ 0, 4th and 24th week (0-4-24w). We found that both schedules of 0-4-12w and 0-4-24w induced higher level of antigen specific IL-2, IFN-γ and TNF-α than 0-3-6w immunization. Among them, 0-4-12w induced the highest level of IL-2, which is a key cytokine mainly produced by T CM . Moreover, by cultured IFN-γ ELISPOT and cell proliferation assay etc., we found that the vaccination schedule of 0-4-12w elicited higher numbers of T CM like cells, stronger T CM - mediated immune responses and higher protective efficacy against M. bovis BCG challenge than 0-3-6w did. It suggests that prolonging the vaccination interval of TB subunit vaccine to some extent contributes to inducing more abundant T CM like cells and providing stronger immune protection against mycobacteria infection. Copyright © 2018. Published by Elsevier Ltd.

Radionuclide desorption kinetics on synthetic Zn/Ni-labeled montmorillonite nanoparticles

NASA Astrophysics Data System (ADS)

Huber, F. M.; Heck, S.; Truche, L.; Bouby, M.; Brendlé, J.; Hoess, P.; Schäfer, T.

2015-01-01

Sorption/desorption kinetics for selected radionuclides (99Tc(VII), 232Th(IV), 233U(VI), 237Np(V), 242Pu and 243Am(III)) under Grimsel (Switzerland) ground water conditions (pH 9.7 and ionic strength of ∼1 mM) in the presence of synthetic Zn or Ni containing montmorillonite nanoparticles and granodiorite fracture filling material (FFM) from Grimsel were examined in batch studies. The structurally bound Zn or Ni in the octahedral sheet of the synthetic colloids rendered them suitable as colloid markers. Only a weak interaction of the montmorillonite colloids with the fracture filling material occurs over the experimental duration of 10,000 h (∼13 months). The tri- and tetravalent radionuclides are initially strongly associated with nanoparticles in contrast to 99Tc(VII), 233U(VI) and 237Np(V) which showed no sorption to the montmorillonite colloids. Radionuclide desorption of the nanoparticles followed by sorption to the fracture filling material is observed for 232Th(IV), 242Pu and 243Am(III). Based on the conceptual model that the driving force for the kinetically controlled radionuclide desorption from nanoparticles and subsequent association to the FFM is the excess in surface area offered by the FFM, the observed desorption kinetics are related to the colloid/FFM surface area ratio. The observed decrease in concentration of the redox sensitive elements 99Tc(VII), 233U(VI) and 237Np(V) may be explained by reduction to lower oxidation states in line with Eh-pH conditions prevailing in the experiments and thermodynamic considerations leading to (i) precipitation of a sparingly soluble phase, (ii) sorption to the fracture filling material, (iii) possible formation of eigencolloids and/or (iv) sorption to the montmorillonite colloids. Subsequent to the sorption/desorption kinetics study, an additional experiment was conducted investigating the potential remobilization of radionuclides/colloids attached to the FFM used in the sorption/desorption kinetic experiments by contacting this FFM with pure Grimsel groundwater for 7 days. A positive correlation of 242Pu, 232Th(IV) and 237Np was observed with the Zn and Ni concentrations in the desorption experiments indicating a remobilization of sorbed montmorillonite colloids. The results of the study in hand highlight (i) the novel use of structural labeled colloids to decrease the uncertainties in the determination of nanoparticle attachment providing more confidence in the derived radionuclide desorption rates. Moreover, the data illustrate (ii) the importance of radionuclide colloid desorption to be considered in the analysis and application of colloid facilitated transport both in laboratory or in-situ experiments and numerical model simulations and (iii) a possible remobilization of sorbed colloids and associated radionuclides by desorption from the matrix material (FFM) under non-equilibrium conditions.

Wind-tunnel investigation of longitudinal and lateral-directional stability and control characteristics of a 0.237-scale model of a remotely piloted research vehicle with a thick, high-aspect-ratio supercritical wing

NASA Technical Reports Server (NTRS)

Byrdsong, T. A.; Brooks, C. W., Jr.

1980-01-01

A 0.237-scale model of a remotely piloted research vehicle equipped with a thick, high-aspect-ratio supercritical wing was tested in the Langley 8-foot transonic tunnel to provide experimental data for a prediction of the static stability and control characteristics of the research vehicle as well as to provide an estimate of vehicle flight characteristics for a computer simulation program used in the planning and execution of specific flight-research mission. Data were obtained at a Reynolds number of 16.5 x 10 to the 6th power per meter for Mach numbers up to 0.92. The results indicate regions of longitudinal instability; however, an adequate margin of longitudinal stability exists at a selected cruise condition. Satisfactory effectiveness of pitch, roll, and yaw control was also demonstrated.

KSC-06pd2072

NASA Image and Video Library

2006-09-07

KENNEDY SPACE CENTER, FLA. - The lights on Launch Pad 39B paint columns of light in the water next to the pad where Space Shuttle Atlantis is illuminated. Atlantis was originally scheduled to launch on Aug. 27, but a scrub was called by mission managers due to a concern with fuel cell 1. Atlantis is scheduled to lift off at 11:41 a.m. EDT Sept. 8. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Ken Thornsley

78 FR 62293 - Safety Zone, Oyster Festival 30th Anniversary Fireworks Display, Oyster Bay; Oyster Bay, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-15

... Safety Zone, Oyster Festival 30th Anniversary Fireworks Display, Oyster Bay; Oyster Bay, NY AGENCY: Coast... zone on the navigable waters of Oyster Bay near Oyster Bay, NY for the Oyster Festival 30th Anniversary... Oyster Festival 30th Anniversary Fireworks Display is scheduled for October 19, 2013 and is one of...

Fission cross sections of some thorium, uranium, neptunium and plutonium isotopes relative to /sup 235/U

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meadows, J W

1983-10-01

Earlier results from the measurements, at this Laboratory, of the fission cross sections of /sup 230/Th, /sup 232/Th, /sup 233/U, /sup 234/U, /sup 236/U, /sup 238/U, /sup 237/Np, /sup 239/Pu, /sup 240/Pu, and /sup 242/Pu relative to /sup 235/U are reviewed with revisions to include changes in data processing procedures, alpha half lives and thermal fission cross sections. Some new data have also been included. The current experimental methods and procedures and the sample assay methods are described in detail and the sources of error are presented in a systematic manner. 38 references.

What, When and Why to Outsource -- Help is on the Way

DTIC Science & Technology

1999-04-01

Szilagyi , Jr., and Marc J. Wallace, Jr.; Organizational Behavior and Performance, 4th Edition; (Scott, Foresman and Company; Glenview, Illinois; 1987...Symposium, 24 May 1996. 12 Holland, 236-237. 13 Szilagyi and Wallace, 50-52. 14 Odeen, 81. 15 House, Report to the Chairman, Subcommittee on Military...Magazine of the Institute of Management Accountants 80, Issue 1 (July 1998): [45-47]. Szilagyi , Jr., Andrew D., and Marc J. Wallace, Jr

World Air Travel Demand, 1950-1980

NASA Technical Reports Server (NTRS)

Sarames, G. N.

1972-01-01

Total world scheduled air passenger traffic carried by the airlines of the International Civil Aviation Organization (ICAO), excluding the U.S.S.R., increased from 17.4 billion passenger miles in 1950 to 237.4 billion in 1970. This represents an average annual growth rate of 14% during the past two decades. The U.S.S.R. became a member of ICAO in 1970, and Aeroflot - the only Russian airline - reported 49 billion passenger miles for 1970. This traffic, which encompasses both domestic and international travel as well as some nonscheduled flights, is not included in the ICAO world totals shown in this report.

Food-based Science Curriculum Increases 4th Graders Multidisciplinary Science Knowledge

PubMed Central

Hovland, Jana A.; Carraway-Stage, Virginia G.; Cela, Artenida; Collins, Caitlin; Díaz, Sebastián R.; Collins, Angelo; Duffrin, Melani W.

2013-01-01

Health professionals and policymakers are asking educators to place more emphasis on food and nutrition education. Integrating these topics into science curricula using hand-on, food-based activities may strengthen students’ understanding of science concepts. The Food, Math, and Science Teaching Enhancement Resource (FoodMASTER) Initiative is a compilation of programs aimed at using food as a tool to teach mathematics and science. Previous studies have shown that students experiencing the FoodMASTER curriculum were very excited about the activities, became increasingly interested in the subject matter of food, and were able to conduct scientific observations. The purpose of this study was to: 1) assess 4th graders food-related multidisciplinary science knowledge, and 2) compare gains in food-related science knowledge after implementation of an integrated, food-based curriculum. During the 2009–2010 school year, FoodMASTER researchers implemented a hands-on, food-based intermediate curriculum in eighteen 4th grade classrooms in Ohio (n=9) and North Carolina (n=9). Sixteen classrooms in Ohio (n=8) and North Carolina (n=8), following their standard science curricula, served as comparison classrooms. Students completed a researcher-developed science knowledge exam, consisting of 13 multiple-choice questions administered pre- and post-test. Only subjects with pre- and post-test scores were entered into the sample (Intervention n=343; Control n=237). No significant differences were observed between groups at pre-test. At post-test, the intervention group scored (9.95±2.00) significantly higher (p=.000) than the control group (8.84±2.37) on a 13-point scale. These findings suggest the FoodMASTER intermediate curriculum is more effective than a standard science curriculum in increasing students’ multidisciplinary science knowledge related to food. PMID:25152539

The Relationship Between Cost Growth and Schedule Growth

DTIC Science & Technology

2003-01-01

Relationship between Cost Growth and Schedule Growth, 35th DoDCAS, SCEA 2002, Integrated Program Management Conference (IPMC) 2002, R. L. Coleman...currently valid OMB control number. 1. REPORT DATE 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The Relationship Between Cost...

2. VIEW EAST, REAR. see also WV2371, WV2372, WV2373, WV23710, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. VIEW EAST, REAR. see also WV-237-1, WV-237-2, WV-237-3, WV-237-10, WV-237-F-2, WV-237-G-3 and historic photographs WV-237-11, WV-237-12, WV-237-13, WV-237-14, WV-237-18, WV-237-F-5) - Parsons Nursery, Original Wash House, South side of U.S. Route 219, Parsons, Tucker County, WV

Civics Framework for the 2006 National Assessment of Educational Progress. NAEP Civics Project

ERIC Educational Resources Information Center

National Assessment Governing Board, 2007

2007-01-01

To gauge the civic knowledge and skills of the nation's 4th-, 8th-, and 12th-grade students, an assessment has been scheduled for 2006 by the National Assessment of Educational Progress (NAEP). This assessment will enable NAEP to report on trends in civics achievement from 1998 to 2006. The National Assessment Governing Board (NAGB), NAEP's…

Understanding Risk

DTIC Science & Technology

1990-03-21

those of the author and do not necessarily reflect the vievs of the Departmcnt cf Defenni or any of its agencies. Th’Is doci’.ent may not Le released...Lewin, Montgomery as a Military Commander, p. 234. 11. Ryan, p. 72. 12. Chester Wilmot , The Struggle for Europe, p. 497. 13. Ambrose, p. 348. 14. Dwight...19. Ryan, p. 542. 20. Ibid., p. 114. 21. Dixon, p. 146. 22. Lewin, pp. 237-238. 23. Wilmot , p. 497. 24. Dixon, p. 400. 25. Omar Bradley, A Soldier’s

Military Review. Volume 57, Number 5, May 1977

DTIC Science & Technology

1977-05-01

of the Uuited States for F16rnl Yt·nr 1977, 20 .Jnnuury J97G, pP 5·6. 0 Donald H. Rumsfeld, Ann11ul Dc/l’JI8l’ D().JJt!Th11().1!t Rcvort Fiscal Year...3,938 4,711 5,220 Portugal Escudos 12,538 14,699 16,046 16,736 25,108 19,898 18,500 Turkey Liras 6,237 8,487 9,961 12,192 15,831 United Kingdom

Proceedings of the Annual ONR/CADRC Decision-Support Workshop (6th), Held in Quantico, Virginia, on 8-9 Sep 2004. Interoperability

DTIC Science & Technology

2004-11-01

fixed schedule checkups and overhauls), Underway Replenishment (the goal being operation in sea states 3 and higher via technical improvements to...determine whether sufficient local resources are available to deal with current conditions. Scheduling Agent: Assists the Emergency Operations Bureau to...will commence per predefined schedule within 15 minutes) and subsequently alerts its subscribers that the rolling power blackout has commenced. The

Real-Time Tomography Mooring

DTIC Science & Technology

1992-06-01

Vi th this sampling schedule the data logger has enough (data. storage capacity for, a five yea r deploymeneit-. SYsteim specifica tionis are shown...sit [I t ille check is pwrformed as a virttial device. called -Ilinei check". which is scheduled in the task tabhe aid(] executed by the systsenm cot...PCI as FSK carrier detect input- add function (5) to do timer/counter control - stop counter when defaults set I 6. Instrument scheduler software

Program and Abstracts of the Society for Research on Biological Rhythms (2nd) Held in Jacksonville, Florida on 9-13 May 1990

DTIC Science & Technology

1991-07-15

4 Tram Schedule ................................................. 5 Amelia Island.................................................. 6 Program... Schedule .................................................. 7 Scientific Program.................................................. 8 Abstracts...and 5 4 -4- TRAM SCHEDULE 6" I Th)e Ameha Isand Tra-s 5 1 p taior, around teP I da-ly basis f~cn 6 1 5 a -MARSHSIDE Ia m Tra-T Stc-,S a’e -.E TRAM I

Significance of electronic health records: A comparative study of vaccination rates in patients with sickle cell disease.

PubMed

Korur, Asli; Asma, Süheyl; Gereklioglu, Cigdem; Solmaz, Soner; Boga, Can; Ozsahin, Akatlı Kürsat; Kut, Altug

2017-01-01

In this study, we investigated the influence of electronic health records (EHR) and electronic vaccination schedule applications on the vaccination status of patients who were admitted to our Center for the treatment of sickle cell disease (SCD). The vaccination status against influenza and pneumococcus infection was determined in 93 patients who were admitted to the hematology outpatient clinic, Baskent University Adana Hospital from April 2004 to March 2009. The vaccination status was then re-evaluated following establishment of EHR and electronic vaccination schedules in 2012. Of the 93 patients with SCD 21.5% (n = 20) were vaccinated against pneumococcus and 21.5% (n = 20) were regularly vaccinated against influenza. When the vaccination rates of 59 of 93 patients who presented for their regular control examinations were analyzed following establishment of EHR and vaccination schedules in 2012, these rates were 49.2% (n = 29) and 50.8% (n = 30) for influenza and pneumococcus, respectively, after EHR; there were 23.7% (n = 14) and 20.3% (n = 12), respectively, before EHR. A statistically significant difference was found between the vaccination rates before and after EHR (p < 0.05). Although viral and bacterial infections are life-threatening health problems in patients with SCD, the vaccination rates were low in high-risk patients. However, these rates increased after application of electronic vaccination schedules.

Significance of electronic health records: A comparative study of vaccination rates in patients with sickle cell disease

PubMed Central

Korur, Asli; Asma, Süheyl; Gereklioglu, Cigdem; Solmaz, Soner; Boga, Can; Ozsahin, Akatlı Kürsat; Kut, Altug

2017-01-01

Objective: In this study, we investigated the influence of electronic health records (EHR) and electronic vaccination schedule applications on the vaccination status of patients who were admitted to our Center for the treatment of sickle cell disease (SCD). Methods: The vaccination status against influenza and pneumococcus infection was determined in 93 patients who were admitted to the hematology outpatient clinic, Baskent University Adana Hospital from April 2004 to March 2009. The vaccination status was then re-evaluated following establishment of EHR and electronic vaccination schedules in 2012. Results: Of the 93 patients with SCD 21.5% (n = 20) were vaccinated against pneumococcus and 21.5% (n = 20) were regularly vaccinated against influenza. When the vaccination rates of 59 of 93 patients who presented for their regular control examinations were analyzed following establishment of EHR and vaccination schedules in 2012, these rates were 49.2% (n = 29) and 50.8% (n = 30) for influenza and pneumococcus, respectively, after EHR; there were 23.7% (n = 14) and 20.3% (n = 12), respectively, before EHR. A statistically significant difference was found between the vaccination rates before and after EHR (p < 0.05). Conclusion: Although viral and bacterial infections are life-threatening health problems in patients with SCD, the vaccination rates were low in high-risk patients. However, these rates increased after application of electronic vaccination schedules. PMID:28811769

Investigation of heavy-ion fusion with deformed surface diffuseness: Actinide and lanthanide targets

NASA Astrophysics Data System (ADS)

Alavi, S. A.; Dehghani, V.

2017-05-01

By using a deformed Broglia-Winther nuclear interaction potential in the framework of the WKB method, the near- and above-barrier heavy-ion-fusion cross sections of 16O with some lanthanides and actinides have been calculated. The effect of deformed surface diffuseness on the nuclear interaction potential, the effective interaction potential at distinct angle, barrier position, barrier height, cross section at each angles, and fusion cross sections of 16O+147Sm,150Nd,154Sm , and 166Er and 16O+232Th,238U,237Np , and 248Cm have been studied. The differences between the results obtained by using deformed surface diffuseness and those obtained by using constant surface diffuseness were noticeable. Good agreement between experimental data and theoretical calculation with deformed surface diffuseness were observed for 16O+147Sm,154Sm,166Er,238U,237Np , and 248Cm reactions. It has been observed that deformed surface diffuseness plays a significant role in heavy-ion-fusion studies.

2. VIEW SOUTH. (see also WV2371, WV2373, WV23710 and historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. VIEW SOUTH. (see also WV-237-1, WV-237-3, WV-237-10 and historic photographs WV-237-11, WV-237-12, WV-237-13, WV-237-14, WV-237-18, WV-237-22) - Parsons Nursery, Workshop-Warehouse, South side of U.S. Route 219, Parsons, Tucker County, WV

Fission fragments mass distributions of nuclei populated by the multinucleon transfer channels of the 18O + 232Th reaction

NASA Astrophysics Data System (ADS)

Léguillon, R.; Nishio, K.; Hirose, K.; Makii, H.; Nishinaka, I.; Orlandi, R.; Tsukada, K.; Smallcombe, J.; Chiba, S.; Aritomo, Y.; Ohtsuki, T.; Tatsuzawa, R.; Takaki, N.; Tamura, N.; Goto, S.; Tsekhanovich, I.; Petrache, C. M.; Andreyev, A. N.

2016-10-01

It is shown that the multinucleon transfer reactions is a powerful tool to study fission of exotic neutron-rich actinide nuclei, which cannot be accessed by particle-capture or heavy-ion fusion reactions. In this work, multinucleon transfer channels of the 18O + 232Th reaction are used to study fission of fourteen nuclei 231,232,233,234Th, 232,233,234,235,236Pa, and 234,235,236,237,238U. Identification of fissioning nuclei and of their excitation energy is performed on an event-by-event basis, through the measurement of outgoing ejectile particle in coincidence with fission fragments. Fission fragment mass distributions are measured for each transfer channel, in selected bins of excitation energy. In particular, the mass distributions of 231,234Th and 234,235,236Pa are measured for the first time. Predominantly asymmetric fission is observed at low excitation energies for all studied cases, with a gradual increase of the symmetric mode towards higher excitation energy. The experimental distributions are found to be in general agreement with predictions of the fluctuation-dissipation model.

KSC-2009-4839

NASA Image and Video Library

2009-08-24

CAPE CANAVERAL, Fla. – Xenon lights over Launch Pad 39A at NASA's Kennedy Space Center in Florida compete with the lightning strike seen to the left. Space shuttle Discovery is on the pad waiting for a scheduled liftoff on the STS-128 mission. Launch was scrubbed due to the weather conditions that violated the limitations for liftoff. Another launch attempt was scheduled for 1:10 a.m. Aug. 26. Discovery's 13-day mission will deliver more than 7 tons of supplies, science racks and equipment, as well as additional environmental hardware to sustain six crew members on the International Space Station. The equipment includes a freezer to store research samples, a new sleeping compartment and the COLBERT treadmill. The mission is the 128th in the Space Shuttle Program, the 37th flight of Discovery and the 30th station assembly flight. Photo credit: NASA/Ben Cooper

A Cost Comparison Between Active and Naval Reserve Force FFG 7 Class Ships

DTIC Science & Technology

1993-06-01

so in our hypothetical depreciation schedule 1/30th of the depreciable cost would be expensed each year. Under GAAP , the historical cost of the asset...and Support Costs (VAMOSC) data base provided by the* aval Center For Cost Analysis. The thesis also sets up theoretical depreciation schedules for...VAMOSC) data base provided by the Naval Center for Cost Analysis. The thesis also sets up theoretical depreciation schedules for selected ships to

Unit Specific Crew Rest Strategies: Phase 1 Evaluation of the 1/212th Aviation Battalion during Shiftwork Transitions

DTIC Science & Technology

1994-01-01

but do not provide strategies or specific schedules of crew rest tailored to the- unit’s specific mission demands, environmental conditions, and...and the impact of mission driven work schedules and environmental conditions on crew rest quality. Phase II provides rhythms, sleep/wake cycles...shiftwork schedules , and methods for regulating the body’s biological clock to prevent sleep loss during characteristic mission. This report contains a

Understanding Ecological Factors Associated With Bullying Across the Elementary to Middle School Transition in the United States.

PubMed

Espelage, Dorothy L; Hong, Jun Sung; Rao, Mrinalini A; Thornberg, Robert

2015-01-01

This study examines sociodemographic characteristics and social-environmental factors associated with bullying during the elementary to middle school transition from a sample of 5th-grade students (n = 300) in 3 elementary schools at Time 1. Of these, 237 participated at Time 2 as 6th-grade students. Using cluster analyses, we found groups of students who reported no increase in bullying, some decrease in bullying, and some increase in bullying. Students who reported increases in bullying also reported decreases in school belongingness and teacher affiliation and increases in teacher dissatisfaction. Students who reported decreases in bullying also reported decreases in victimization. These findings suggest that changes across the transition in students' relations to school and their teachers are predictive of changes in bullying.

Proceedings of the Annual ACM Symposium (11th) on Principles of Distributed Computing Held in Vancouver, British Columbia, Canada on 10-12 Aug 1992

DTIC Science & Technology

1992-08-10

scheduler’s strategy. At the beginning of the is delayed at this state. A routing edge (Si,Tj), execution, the scheduler delays all messages sent for...graph G and Appendix). We remark that the choice of "play" the role ý-’ the scheduler . The scheduler’s constants in the above definition is not...34’ Annmul Symposium ical wakeup . Also, assume that during [t, t + x], for on Foundations of Computer Science. IEEE, t > 2n, a specific route of length at most

Development and Evaluation of a Parallel Reaction Monitoring Strategy for Large-Scale Targeted Metabolomics Quantification.

PubMed

Zhou, Juntuo; Liu, Huiying; Liu, Yang; Liu, Jia; Zhao, Xuyang; Yin, Yuxin

2016-04-19

Recent advances in mass spectrometers which have yielded higher resolution and faster scanning speeds have expanded their application in metabolomics of diverse diseases. Using a quadrupole-Orbitrap LC-MS system, we developed an efficient large-scale quantitative method targeting 237 metabolites involved in various metabolic pathways using scheduled, parallel reaction monitoring (PRM). We assessed the dynamic range, linearity, reproducibility, and system suitability of the PRM assay by measuring concentration curves, biological samples, and clinical serum samples. The quantification performances of PRM and MS1-based assays in Q-Exactive were compared, and the MRM assay in QTRAP 6500 was also compared. The PRM assay monitoring 237 polar metabolites showed greater reproducibility and quantitative accuracy than MS1-based quantification and also showed greater flexibility in postacquisition assay refinement than the MRM assay in QTRAP 6500. We present a workflow for convenient PRM data processing using Skyline software which is free of charge. In this study we have established a reliable PRM methodology on a quadrupole-Orbitrap platform for evaluation of large-scale targeted metabolomics, which provides a new choice for basic and clinical metabolomics study.

Applications of neutron activation analysis in determination of natural and man-made radionuclides, including PA-231

NASA Astrophysics Data System (ADS)

Byrne, A. R.; Benedik, L.

1999-01-01

Neutron activation analysis (NAA), being essentially an isotopic and not an elemental method of analysis, is capable of determining a number of important radionuclides of radioecological interest by transformation into another, more easily quantifiable radionuclide. The nuclear characteristics which favour this technique may be summarized in an advantage factor relative to radiometric analysis of the original radioanalyte. Well known or hardly known examples include235U,238U,232Th,230Th,129I,99Tc,237Np and231Pa; a number of these are discussed and illustrated in analysis of real samples of environmental and biological origin. In particular, determination of231Pa by RNAA was performed using both postirradiation and preseparation methods. Application of INAA to enable the use of238U and232Th as endogenous (internal) radiotracers in alpha spectrometric analyses of uranium and thorium radioisotopes in radioecological studies is described, also allowing independent data sets to be obtained for quality control.

Proceedings of the International Conference on Lasers 󈨝 (12th), Held in New Orleans, Louisiana on December 3-8, 1989.

DTIC Science & Technology

1990-01-01

schedule soon, while in the percutaneous one auto-fluorescence spectroscopy could be the closest technique to be effectively included in the angioplasty...experiments Dashed line: Amplifier mode experiments ( scheduled ) Fig. 3 Schematic of laser, pulsed power, and X-ray preionizer 3. Pulsed Power 4. X-Ray...of KrF Amplifier * scheduled ** estimated value 120 CONDENSED PHASE RARE GAS HALIDE EXCIPLEX LASERS V. Ara Apkarian Professor of Chemistry Department

KSC-06pd2047

NASA Image and Video Library

2006-09-06

KENNEDY SPACE CENTER, FLA. - Space Shuttle Atlantis is bathed in light on Launch Pad 39B. Atlantis was originally scheduled to launch at 12:29 p.m. EDT on this date, but a 24-hour scrub was called by mission managers due to a concern with Fuel Cell 1. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Jim Grossmann

KSC-06pd2066

NASA Image and Video Library

2006-09-07

KENNEDY SPACE CENTER, FLA. - Storm clouds roll across Launch Pad 39B where Space Shuttle Atlantis still sits on the pad. Atlantis was originally scheduled to launch Aug. 27, but a scrub was called by mission managers due to a concern with fuel cell 1. Towering above the shuttle is the 80-foot lightning mast. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Ken Thornsley

KSC-06pd2064

NASA Image and Video Library

2006-09-07

KENNEDY SPACE CENTER, FLA. - Storm clouds gather behind Space Shuttle Atlantis on Launch Pad 39B. Atlantis was originally scheduled to launch on Aug. 27, but a scrub was called by mission managers due to a concern with fuel cell 1. Towering above the shuttle is the 80-foot lightning mast. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Ken Thornsley

KSC-06pd2065

NASA Image and Video Library

2006-09-07

KENNEDY SPACE CENTER, FLA. - A heavy bank of storm clouds gather behind Space Shuttle Atlantis on Launch Pad 39B. Atlantis was originally scheduled to launch Aug. 27, but a scrub was called by mission managers due to a concern with fuel cell 1. Towering above the shuttle is the 80-foot lightning mast. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Ken Thornsley

75 FR 10483 - Filing Dates for the Pennsylvania Special Election in the 12th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-08

... in the 12th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Pennsylvania has scheduled a Special General Election on May 18... John P. Murtha. Committees required to file reports in connection with the Special General Election on...

76 FR 17124 - Filing Dates for the California Special Election in the 36th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-28

... the 36th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: California has scheduled a special general election on May 17, 2011, to... committees of candidates who participate in the California Special General and Special Runoff Elections shall...

76 FR 45797 - Filing Dates for the New York Special Election in the 9th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-01

... 9th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: New York has scheduled a Special General Election on September 13, 2011, to.... Committees required to file reports in connection with the Special General Election on September 13, 2011...

76 FR 61074 - Reports and Updates on Arctic Research Programs and Projects; Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... UNITED STATES ARCTIC RESEARCH COMMISSION Reports and Updates on Arctic Research Programs and Projects; Meetings Notice is hereby given that the US Arctic Research Commission will hold its 96th meeting... about topics of interest related to research activities in the Arctic. 96th Meeting Schedule: Wed., Oct...

77 FR 56208 - Filing Dates for the Kentucky Special Election in the 4th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... FEDERAL ELECTION COMMISSION [Notice 2012-06] Filing Dates for the Kentucky Special Election in the 4th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Kentucky has scheduled a general election on November 6, 2012, to fill the U.S...

Evaluation of Math Block-Scheduling for Low Performing At-Risk and Economically-Disadvantaged Students

ERIC Educational Resources Information Center

Trice, Toni M.

2017-01-01

Research shows a math achievement gap for at-risk and economically-disadvantaged students in the United States. To address this issue, a Texas school district implemented a 90-minute math block-scheduling program with 8th grade students. Shaped by the academic learning time and social justice theories, the purpose of this quantitative program…

[Effect of extracts of Geranium ayavacense W. (Pasuchaca) on glycemia on rats with experimental diabetes mellitus].

PubMed

Aranda-Ventura, José; Villacrés, Jorge; Mego, Rosario; Delgado, Henry

2014-04-01

To determine if the lyophilized aqueous extract of Geranium ayavacense (Pasuchaca) has any effect on glycemia in rats with experimental diabetes mellitus. Experimental diabetes was induced with alloxan. Rats included in the study met the following criteria: glycemia greater than 200 mg/dL post administration of alloxan, and with a weight greater than 200 g. Rats with experimental diabetes were divided into six groups of eight rats each. Group I received 3 mL of distilled water (control); group II received Geranium ayavacense 12.7 mg/kg; group III received Geranium ayavacense 100 mg/kg; group IV received Geranium ayavacense 200 mg/kg; group V received Geranium ayavacense 300 mg/kg; group VI received Geranium ayavacense 500 mg/kg. Basal glycemia was determined. Glycemia evaluations were performed at the 1st, 3rd, 6th, 12th and 24th hour after administrating the different interventions. Geranium ayavacense groups of 300 and 500 mg/kg decreased glycemia significantly (p <0.01) in every hour assessed after administration of the extract, when compared with the control group. Geranium ayavacense group of 300 mg/kg decreased their blood glucose 8.14; 10.68; 14.87; 19.36 and 23.7% in the 1st, 3rd, 6th, 12th and 24th hour respectively. Under experimental conditions, the aqueous extract of Geranium ayavacense has hypoglycemic effects in rats.

75 FR 62131 - Filing Dates for the New York Special Election in the 29th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-07

... 29th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: New York has scheduled a Special General Election on November 2, 2010, to fill.... Committees required to file reports in connection with the Special General Election on November 2, 2010...

78 FR 53454 - Filing Dates for the Louisiana Special Elections in the 5th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... the 5th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Louisiana has scheduled a Special General Election on October 19, 2013, to fill... Special General and Special Runoff Elections shall file a 12-day Pre-General Report on October 7, 2013; a...

75 FR 17742 - Filing Dates for the Georgia Special Election in the 9th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

... 9th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Georgia has scheduled a special general election on May 11, 2010, to fill the U... participate in the Georgia Special General and Special Runoff Elections shall file a 12-day Pre-General Report...

76 FR 16419 - Filing Dates for the New York Special Election in the 26th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-23

... 26th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: New York has scheduled a Special General Election on May 24, 2011, to fill the.... Committees required to file reports in connection with the Special General Election on May 24, 2011, shall...

78 FR 9916 - Filing Dates for the Missouri Special Election in the 8th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... 8th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Missouri has scheduled a Special General Election on June 4, 2013, to fill the.... Committees required to file reports in connection with the Special General Election on June 4, 2013, shall...

78 FR 32990 - Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-03

...] Special Local Regulation and Safety Zone; America's Cup Sailing Events, San Francisco, CA AGENCY: Coast... ``Louis Vuitton Cup, Red Bull Youth America's Cup and the 34th America's Cup'' regatta scheduled from July... associated with the 34th America's Cup sailing events taking place adjacent to the City of San Francisco...

Extracurricular participation and academic outcomes: testing the over-scheduling hypothesis.

PubMed

Fredricks, Jennifer A

2012-03-01

There is a growing concern that some youth are overscheduled in extracurricular activities, and that this increasing involvement has negative consequences for youth functioning. This article used data from the Educational Longitudinal Study (ELS: 2002), a nationally representative and ethnically diverse longitudinal sample of American high school students, to evaluate this hypothesis (N = 13,130; 50.4% female). On average, 10th graders participated in between 2 and 3 extracurricular activities, for an average of 5 h per week. Only a small percentage of 10th graders reported participating in extracurricular activities at high levels. Moreover, a large percentage of the sample reported no involvement in school-based extracurricular contexts in the after-school hours. Controlling for some demographic factors, prior achievement, and school size, the breadth (i.e., number of extracurricular activities) and the intensity (i.e., time in extracurricular activities) of participation at 10th grade were positively associated with math achievement test scores, grades, and educational expectations at 12th grade. Breadth and intensity of participation at 10th grade also predicted educational status at 2 years post high school. In addition, the non-linear function was significant. At higher breadth and intensity, the academic adjustment of youth declined. Implications of the findings for the over-scheduling hypothesis are discussed.

Airway responses of healthy farmers and nonfarmers to exposure in a swine confinement building.

PubMed

Palmberg, Lena; Larssson, Brit-Marie; Malmberg, Per; Larsson, Kjell

2002-08-01

The objective of the study was to determine whether swine farmers continuously exposed to the farming environment react differently to acute exposure than previously unexposed nonfarmers. Nine healthy nonfarmers, not previously exposed to a farming environment, and eight swine farmers were exposed in a swine confinement building for 3 hours while weighing pigs. Lung function measurements, methacholine challenge tests, and nasal lavages were performed before and after the exposure. Blood samples were drawn repeatedly during the exposure day. Differential cell counts and cytokine levels were analyzed in the nasal lavage fluid and blood. The exposure levels were the same in both groups. Bronchial responsiveness to methacholine increased by a median of 4.0 (25th-75th percentiles 2.2-10.1 among the nonfarmers) and 0.7 (25th-75th percentiles 0.01-3.5 among the farmers) doubled concentration steps. The median serum levels of interleukin-6 increased from 3.8 (25th-75th percentiles <3-5.8) ng/l to 23.7 (25th-75th percentiles 11.6-41.6) ng/l among the nonfarmers and from <3 to 3.8 (25th-75th percentiles 3.1-11.6) ng/l among the swine farmers after the exposure. Swine dust exposure induced a ninefold increase in the total cell counts in the nasal lavage fluid of the nonfarmers, but no significant increase among the swine farmers. The exposure altered lung function and bronchial responsiveness, as well as cell number and cytokines in blood and nasal lavage fluid in previously unexposed nonfarming subjects, whereas only minor alterations were found in the farmers. This finding suggests possible adaptation mechanisms in chronically exposed swine farmers.

Automatic updating of times remaining in surgical cases using bayesian analysis of historical case duration data and "instant messaging" updates from anesthesia providers.

PubMed

Dexter, Franklin; Epstein, Richard H; Lee, John D; Ledolter, Johannes

2009-03-01

Operating room (OR) whiteboards (status displays) communicate times remaining for ongoing cases to perioperative stakeholders (e.g., postanesthesia care unit, anesthesiologists, holding area, and control desks). Usually, scheduled end times are shown for each OR. However, these displays are inaccurate for predicting the time that remains in a case. Once a case scheduled for 2 h has been on-going for 1.5 h, the median time remaining is not 0.5 h but longer, and the amount longer differs among procedures. We derived the conditional Bayesian lower prediction bound of a case's duration, conditional on the minutes of elapsed OR time. Our derivations make use of the posterior predictive distribution of OR times following an exponential of a scaled Student t distribution that depends on the scheduled OR time and several parameters calculated from historical case duration data. The statistical method was implemented using Structured Query Language (SQL) running on the anesthesia information management system (AIMS) database server. In addition, AIMS workstations were sent instant messages displaying a pop-up dialog box asking for anesthesia providers' estimates for remaining times. The dialogs caused negotiated interruptions (i.e., the anesthesia provider could reply immediately, keep the dialog displayed, or defer response). There were no announcements, education, or efforts to promote buy-in. After a case had been in the OR longer than scheduled, the median remaining OR time for the case changes little over time (e.g., 35 min left at 2:30 pm and also at 3:00 pm while the case was still on-going). However, the remaining time differs substantially among surgeons and scheduled procedure(s) (16 min longer [10th percentile], 35 min [50th], and 86 min [90th]). We therefore implemented an automatic method to estimate the times remaining in cases. The system was operational for >119 of each day's 120 5-min intervals. When instant message dialogs appearing on AIMS workstations were used to elicit estimates of times remaining from anesthesia providers, acknowledgment was on average within 1.2 min (95% confidence interval [CI] 1.1-1.3 min). The 90th percentile of latencies was 6.5 min (CI: 4.4-7.0 min). For cases taking nearly as long as or longer than scheduled, each 1 min progression of OR time reduces the median time remaining in a case by <1 min. We implemented automated calculation of times remaining for every case at a 29 OR hospital.

Synchronization of Concurrent Processes

DTIC Science & Technology

1975-07-01

Pettersen Stanford Ur.iversity Artificial Intelligence Laboratory ABSTRACT Th oaoer gives an overview of commonly used synchronization primitives and...wr.ters . ut.l.z.ng the DroDo4d synchronization primitive . The solution is simpler and shorter than other known S’ms The first sections of the paper...un reicr»» side il nrcttaary and Identity by block number) Scheduling, process scheduling, synchronization , mutual exclusion, semaphores , critical

2005 8th Annual Systems Engineering Conference. Volume 2, Wednesday Presentations

DTIC Science & Technology

2005-10-27

Acquisition Programs: An OSD Perspective, Col Warren Anderson, OUSD (AT&L) Defense Systems Implementation of Policy Requiring Systems Engineering Plans...Technical Excellence, Col Warren Anderson, OUSD (AT&L) Defense Systems Applying CMMI to System Safety, Mr. Tom Pfitzer, APT Research, Inc. System...to following pages for Tutorials Schedule) Buffett Lunch Tutorial Tracks (Please refer to following pages for Tutorials Schedule) Reception in

Effective Schedule and Cost Management as a Product Development Lead

NASA Technical Reports Server (NTRS)

Simmons, Cynthia

2015-01-01

The presentation will be given at the 26th Annual Thermal Fluids Analysis Workshop (TFAWS 2015) hosted by the Goddard SpaceFlight Center (GSFC) Thermal Engineering Branch (Code 545). This course provides best practices, helpful tools and lessons learned for staying on plan and day-to-day management of Subsystem flight development after getting Project approval for your Subsystem schedule and budget baseline.

KSC-06pd2137

NASA Image and Video Library

2006-09-09

KENNEDY SPACE CENTER, FLA. - Inside the Launch Control Center, Robbie Ashley, STS-115 payload manager, and Pat Lesley, with United Space Alliance, receive a special award from (at left) Shuttle Launch Director Mike Leinbach and (at right) NASA Flow Director Angie Brewer. Mission STS-115 is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-06pd2134

NASA Image and Video Library

2006-09-09

KENNEDY SPACE CENTER, FLA. - Inside the Launch Control Center, KSC officials turn from their computers to watch through the broad windows the launch of Space Shuttle Atlantis on mission STS-115. Second from left is NASA Test Director Pete Nickolenko. Mission STS-115 is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. sts-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-06pd2078

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Pilot Christopher Ferguson dons his launch and re-entry suit before heading to the launch pad. Ferguson is making his first shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-06pd2079

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Commander Brent Jett dons his launch and re-entry suit before heading to the launch pad. Jett is making his fourth shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-06pd2076

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Mission Specialist Joseph Tanner dons his launch and re-entry suit before heading to the launch pad. Tanner is making his fourth shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-2011-1682

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- House Of Representatives Democratic Leader Nancy Pelosi, from California's 8th District, and other VIPs are at NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history as it lifts off on its final scheduled mission from Launch Pad 39A. While at the space center, they attended a presentation in the Operations Support Building II and toured Orbiter Processing Facilities 1 and 2 where shuttles Atlantis and Endeavour are being prepared for their final missions respectively. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery will make its 39th mission and is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

31 CFR 500.201 - Transactions involving designated foreign countries or their nationals; effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... noted after the country or area. Schedule (1) North Korea, i.e., Korea north of the 38th parallel of north latitude: December 17, 1950. (2) Cambodia: April 17, 1975. (3) North Vietnam; i.e., Vietnam north of the 17th parallel of north latitude: May 5, 1964. (4) South Vietnam, i.e., Vietnam south of the...

Development of a “Fission-proxy” Method for the Measurement of 14-MeV Neutron Fission Yields at CAMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gharibyan, Narek

2016-10-25

Relative fission yield measurements were made for 50 fission products from 25.6±0.5 MeV alpha-induced fission of Th-232. Quantitative comparison of these experimentally measured fission yields with the evaluated fission yields from 14-MeV neutron-induced fission of U-235 demonstrates the feasibility of the proposed fission-proxy method. This new technique, based on the Bohr-independence hypothesis, permits the measurement of fission yields from an alternate reaction pathway (Th-232 + 25.6 MeV α → U-236* vs. U-235 + 14-MeV n → U-236*) given that the fission process associated with the same compound nucleus is independent of its formation. Other suitable systems that can potentially bemore » investigated in this manner include (but are not limited to) Pu-239 and U-237.« less

Astronaut Judith Resnik participates in WETF training

NASA Image and Video Library

1984-05-14

S84-33898 (21 May 1984) --- Astronaut Jon A. McBride, 41-G pilot, assists his crewmate, Astronaut Kathryn D. Sullivan with the glove portion of her extravehicular mobility unit (EMU) prior to Dr. Sullivan's underwater session in the Johnson Space Center's weightless environment training facility (WET-F). Mission specialists Sullivan and David C. Leestma are scheduled for extravehicular activity (EVA) on the Columbia for NASA's 17th scheduled flight.

48 CFR 237.109 - Services of quasi-military armed forces.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Services of quasi-military armed forces. 237.109 Section 237.109 Federal Acquisition Regulations System DEFENSE ACQUISITION... Contracts-General 237.109 Services of quasi-military armed forces. See 237.102-70b for prohibition on...

KSC-2011-1624

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Swarms of people are at the Kennedy Space Center Visitor Complex in Florida to watch space shuttle Discovery lift off on its final scheduled mission from Launch Pad 39A. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1625

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Swarms of people are at the Kennedy Space Center Visitor Complex in Florida to watch space shuttle Discovery lift off on its final scheduled mission from Launch Pad 39A. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1623

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Swarms of people are at the Kennedy Space Center Visitor Complex in Florida to watch space shuttle Discovery lift off on its final scheduled mission from Launch Pad 39A. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1622

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Swarms of people are at the Kennedy Space Center Visitor Complex in Florida to watch space shuttle Discovery lift off on its final scheduled mission from Launch Pad 39A. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1626

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Swarms of people are at the Kennedy Space Center Visitor Complex in Florida to watch space shuttle Discovery lift off on its final scheduled mission from Launch Pad 39A. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

Physical exercise accelerates reentrainment of human sleep-wake cycle but not of plasma melatonin rhythm to 8-h phase-advanced sleep schedule.

PubMed

Yamanaka, Yujiro; Hashimoto, Satoko; Tanahashi, Yusuke; Nishide, Shin-Ya; Honma, Sato; Honma, Ken-Ichi

2010-03-01

Effects of timed physical exercise were examined on the reentrainment of sleep-wake cycle and circadian rhythms to an 8-h phase-advanced sleep schedule. Seventeen male adults spent 12 days in a temporal isolation facility with dim light conditions (<10 lux). The sleep schedule was phase-advanced by 8 h from their habitual sleep times for 4 days, which was followed by a free-run session for 6 days, during which the subjects were deprived of time cues. During the shift schedule, the exercise group (n = 9) performed physical exercise with a bicycle ergometer in the early and middle waking period for 2 h each. The control group (n = 8) sat on a chair at those times. Their sleep-wake cycles were monitored every day by polysomnography and/or weight sensor equipped with a bed. The circadian rhythm in plasma melatonin was measured on the baseline day before phase shift: on the 4th day of shift schedule and the 5th day of free-run. As a result, the sleep-onset on the first day of free-run in the exercise group was significantly phase-advanced from that in the control and from the baseline. On the other hand, the circadian melatonin rhythm was significantly phase-delayed in the both groups, showing internal desynchronization of the circadian rhythms. The sleep-wake cycle resynchronized to the melatonin rhythm by either phase-advance or phase-delay shifts in the free-run session. These findings indicate that the reentrainment of the sleep-wake cycle to a phase-advanced schedule occurs independent of the circadian pacemaker and is accelerated by timed physical exercise.

Feasibility Report and Environmental Assessment Nogales Wash and Tributaries.Nogales, Arizona (Revision)

DTIC Science & Technology

1988-09-07

Office) IS. SECURITY CLASS. (of the report) Unclassified IS.. DECLASSIIFICATION/DOWNGRADING SCHEDULE 16. DISTRIBUTION STATEMENT (of th,. Report... SCHEDULE 5-19 L. ECCNCV!, I EVALUATION 5-19 M. NATIONAL ECONCMIC DEELOPMEN 5-19 N. RECOMMENDED PLAN 5-2C VI. PLAN IMPLEIENTATION 6-1 A. DIVISION OF PLAN...the possibility of flash flooding while residents sleep . 2. Historical Flood Damages The twin cities of Nogales, Arizona and Nogales, Sonora have a

TGF-β/Smad signaling pathway regulates Th17/Treg balance during Echinococcus multilocularis infection.

PubMed

Pang, Nannan; Zhang, Fengbo; Ma, Xiumin; Zhu, Yuejie; Zhao, Hui; Xin, Yan; Wang, Song; Chen, Zhaolun; Wen, Hao; Ding, Jianbing

2014-05-01

Alveolar echinococcosis (AE) is a severe parasitic disease caused by the infection of Echinococcus multilocularis (Em). Very little is known on the relationship between TGF-β/Smad signaling pathway and Treg/Th17 balance in the infected liver at different periods after Em infection. Using qRT-PCR, immunohistochemistry, flow cytometry and CBA assay, we measured the expression levels of TGF-β, Smad2/3/7, ROR-γt, Foxp3, IL-17, IL-10 and percentages of Th17 cells and Treg cells in mouse AE model, from day 2 to day 270 after infection. In the early stage of infection (day 2 to day 30), Smad7 was up-regulated and the TGF-β pathway was inactivated. In the middle stage of infection (day 30 to day 90), TGF-β and Smad2/3 were up-regulated. And levels of Treg cells, Foxp3, Th17 cells, RORγt, IL-17, IL-10 and IL-6 were significantly increased. In the late stage of infection (day 90 to day 270), Treg cells, Foxp3, TGF-β and IL-10 maintained at high levels whereas Th17 cells and IL-17 decreased significantly. TGF-β/Smad signaling pathway was activated during the chronic infection. Our data suggest that there were Treg/Th17 imbalance in the middle and especially in the late stage of Em infection and that Treg/Th17 imbalance may be regulated by TGF-β/Smad signaling pathway. Treg and Th17 subsets may be involved in regulating immune tolerance and tissue inflammation, and facilitating the long-term survival of Em in the host. Copyright © 2014 Elsevier B.V. All rights reserved.

KSC-06pd2077

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Mission Specialist Steven MacLean dons his launch and re-entry suit before heading to the launch pad. MacLean is with the Canadian Space Agency. MacLean is making his second shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-06pd2082

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Mission Specialist Heidemarie Stefanyshyn-Piper is helped with her launch and re-entry suit before heading to the launch pad. Stefanyshyn-Piper is making her first shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-2011-1681

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- House Of Representatives Democratic Leader Nancy Pelosi, from California's 8th District, is greeted by NASA Kennedy Space Center Director Robert Cabana. Pelosi is at Florida's space center to witness space shuttle Discovery make history as it lifts off on its final scheduled mission from Launch Pad 39A. While at the center, Pelosi attended a presentation in the Operations Support Building II and toured Orbiter Processing Facilities 1 and 2 where shuttles Atlantis and Endeavour are being prepared for their final missions respectively. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery will make its 39th mission and is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

KSC-2011-1683

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- CAPE CANAVERAL, Fla. -- House Of Representatives Democratic Leader Nancy Pelosi, from California's 8th District, fourth from left, and other VIPs pose for a photo with NASA Kennedy Space Center Director Robert Cabana. They are at Florida's space center to witness space shuttle Discovery make history as it lifts off on its final scheduled mission from Launch Pad 39A. While at the center, they attended a presentation in the Operations Support Building II and toured Orbiter Processing Facilities 1 and 2 where shuttles Atlantis and Endeavour are being prepared for their final missions respectively. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery will make its 39th mission and is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

KSC-2011-1685

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- House Of Representatives Democratic Leader Nancy Pelosi, from California's 8th District, left, and United Space Alliance worker Brian Elleman pose for a photo at NASA's Kennedy Space Center in Florida. Pelosi is at the space center to witness space shuttle Discovery make history as it lifts off on its final scheduled mission from Launch Pad 39A. While at the center, Pelosi attended a presentation in the Operations Support Building II and toured Orbiter Processing Facilities 1 and 2 where shuttles Atlantis and Endeavour are being prepared for their final missions respectively. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery will make its 39th mission and is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

Maxwell Paper Anthology. Award-Winning Papers AY 2010

DTIC Science & Technology

2011-04-01

and instructor weapon system officer (WSO), training officer, and wing scheduler, 522d Fighter Squadron, Cannon AFB, New Mexico . At the 34th Bomb...surgeon, HQ USAFE. Ramstein AB, Germany. He has served as the commander of the 27th Special Operations Medical Group, Cannon AFB. New Mexico ...encephalitis.20 In addition, development of li- censed vaccines for yellow fever, mumps, measles, varicella , and oral polio was supervised by

An Analysis of the Implementation of the Standard Accounting, Budgeting and Reporting System (SABRS) in the 4th Marine Division.

DTIC Science & Technology

1980-12-01

REPOR DOCUMENTATION PAGE - 33703 COMPLZT!Nc PORN I.RPRNUM69M L. GOV"T ACCESSION NO. I. RECIPIEN4TS CATALOG NUNS9R a. TITLE (mds ume An Anaiysi s of th...wagging the dog ." The development schedule for SABRS envisions the three phases of concept formulation, Automated Data Systems (ADS) development and

The influence of intermittent fasting on the circadian pattern of melatonin while controlling for caloric intake, energy expenditure, light exposure, and sleep schedules: A preliminary report.

PubMed

Almeneessier, Aljohara S; Bahammam, Ahmed S; Sharif, Munir M; Bahammam, Salman A; Nashwan, Samar Z; Pandi Perumal, Seithikurippu R; Cardinali, Daniel P; Alzoghaibi, Mohammad

2017-01-01

We hypothesized that if we control for food composition, caloric intake, light exposure, sleep schedule, and exercise, intermittent fasting would not influence the circadian pattern of melatonin. Therefore, we designed this study to assess the effect of intermittent fasting on the circadian pattern of melatonin. Eight healthy volunteers with a mean age of 26.6 ± 4.9 years and body mass index of 23.7 ± 3.5 kg/m 2 reported to the Sleep Disorders Center (the laboratory) on four occasions: (1) adaptation, (2) 4 weeks before Ramadan while performing Islamic intermittent fasting for 1 week (fasting outside Ramadan [FOR]), (3) 1 week before Ramadan (nonfasting baseline [BL]), and (4) during the 2 nd week of Ramadan while fasting ( Ramadan ). The plasma levels of melatonin were measured using enzyme-linked immunoassays at 22:00, 02:00, 04:00, 06:00, and 11:00 h. The light exposure, meal composition, energy expenditure, and sleep schedules remained the same while the participants stayed at the laboratory. The melatonin levels followed the same circadian pattern during the three monitoring periods (BL, FOR, and Ramadan ). The peak melatonin level was at 02:00 h and the trough level was at 11:00 h in all studied periods. Lower melatonin levels at 22:00 h were found during fasting compared to BL. Cosinor analysis revealed no significant changes in the acrophase of melatonin levels. In this preliminary report, under controlled conditions of light exposure, meal composition, energy expenditure, and sleep-wake schedules, intermittent fasting has no significant influence on the circadian pattern of melatonin.

The influence of intermittent fasting on the circadian pattern of melatonin while controlling for caloric intake, energy expenditure, light exposure, and sleep schedules: A preliminary report

PubMed Central

Almeneessier, Aljohara S.; Bahammam, Ahmed S.; Sharif, Munir M.; Bahammam, Salman A.; Nashwan, Samar Z.; Pandi Perumal, Seithikurippu R.; Cardinali, Daniel P.; Alzoghaibi, Mohammad

2017-01-01

AIMS: We hypothesized that if we control for food composition, caloric intake, light exposure, sleep schedule, and exercise, intermittent fasting would not influence the circadian pattern of melatonin. Therefore, we designed this study to assess the effect of intermittent fasting on the circadian pattern of melatonin. METHODS: Eight healthy volunteers with a mean age of 26.6 ± 4.9 years and body mass index of 23.7 ± 3.5 kg/m2 reported to the Sleep Disorders Center (the laboratory) on four occasions: (1) adaptation, (2) 4 weeks before Ramadan while performing Islamic intermittent fasting for 1 week (fasting outside Ramadan [FOR]), (3) 1 week before Ramadan (nonfasting baseline [BL]), and (4) during the 2nd week of Ramadan while fasting (Ramadan). The plasma levels of melatonin were measured using enzyme-linked immunoassays at 22:00, 02:00, 04:00, 06:00, and 11:00 h. The light exposure, meal composition, energy expenditure, and sleep schedules remained the same while the participants stayed at the laboratory. RESULTS: The melatonin levels followed the same circadian pattern during the three monitoring periods (BL, FOR, and Ramadan). The peak melatonin level was at 02:00 h and the trough level was at 11:00 h in all studied periods. Lower melatonin levels at 22:00 h were found during fasting compared to BL. Cosinor analysis revealed no significant changes in the acrophase of melatonin levels. CONCLUSIONS: In this preliminary report, under controlled conditions of light exposure, meal composition, energy expenditure, and sleep-wake schedules, intermittent fasting has no significant influence on the circadian pattern of melatonin. PMID:28808490

48 CFR 237.172 - Service Contracts Surveillance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Surveillance. 237.172 Section 237.172 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...-General 237.172 Service Contracts Surveillance. Ensure that quality assurance surveillance plans are....) Retain quality assurance surveillance plans in the official contract file. See https://sam.dau.mil, Step...

48 CFR 237.172 - Service Contracts Surveillance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Surveillance. 237.172 Section 237.172 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...-General 237.172 Service Contracts Surveillance. Ensure that quality assurance surveillance plans are....) Retain quality assurance surveillance plans in the official contract file. See https://sam.dau.mil, Step...

48 CFR 237.172 - Service Contracts Surveillance.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Surveillance. 237.172 Section 237.172 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...-General 237.172 Service Contracts Surveillance. Ensure that quality assurance surveillance plans are....) Retain quality assurance surveillance plans in the official contract file. See https://sam.dau.mil, Step...

48 CFR 237.172 - Service Contracts Surveillance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Surveillance. 237.172 Section 237.172 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...-General 237.172 Service Contracts Surveillance. Ensure that quality assurance surveillance plans are....) Retain quality assurance surveillance plans in the official contract file. See https://sam.dau.mil, Step...

48 CFR 237.172 - Service Contracts Surveillance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Surveillance. 237.172 Section 237.172 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS...-General 237.172 Service Contracts Surveillance. Ensure that quality assurance surveillance plans are....) Retain quality assurance surveillance plans in the official contract file. See https://sam.dau.mil, Step...

49 CFR 237.1 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Application. 237.1 Section 237.1 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.1 Application. (a) Except as provided in paragraphs (b) or...

46 CFR 169.237 - Inspection standards.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Inspection standards. 169.237 Section 169.237 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.237 Inspection standards. Vessels are inspected for compliance...

46 CFR 169.237 - Inspection standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Inspection standards. 169.237 Section 169.237 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.237 Inspection standards. Vessels are inspected for compliance...

40 CFR 745.237 - Inspections.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Inspections. 745.237 Section 745.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.237...

40 CFR 745.237 - Inspections.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Inspections. 745.237 Section 745.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.237...

40 CFR 745.237 - Inspections.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Inspections. 745.237 Section 745.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.237...

40 CFR 745.237 - Inspections.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Inspections. 745.237 Section 745.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.237...

40 CFR 745.237 - Inspections.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Inspections. 745.237 Section 745.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.237...

Role of ser-237 in the substrate specificity of the carbapenem-hydrolyzing class A beta-lactamase Sme-1.

PubMed

Sougakoff, W; Naas, T; Nordmann, P; Collatz, E; Jarlier, V

1999-08-17

The role of the serine residue found at position 237 in the carbapenemase Sme-1 has been investigated by constructing a mutant in which Ser-237 was replaced by an alanine. The S237A mutant showed a catalytic behavior against penicillins and aztreonam very similar to that of Sme-1. By contrast, S237A was characterized by a reduced catalytic efficiency against cephems, such as cephalothin and cephaloridine. In addition, the weak activity of Sme-1 against the cephamycin cefoxitin was hardly detectable with the mutant enzyme. Finally, the Ser-237-->Ala mutation resulted in a marked decrease in catalytic activity against imipenem, showing that Ser-237 contributes to the carbapenemase activity of the class A beta-lactamase Sme-1.

Environmental Assessment for BRAC Actions for the 137th Airlift Wing Relocation, KC-135R Aircraft Robust, and Associated Construction at the 507th Air Refueling Wing Tinker Air Force Base, Oklahoma

DTIC Science & Technology

2007-10-01

increase in both civilian and military personnel. In the 1970s, the base took over management of new weapons including the A-7D Corsair , the E-3A...one- bay hangar that would be utilized for scheduled maintenance. The existing ramp would be expanded to provide hangar access. Buildings 1041 and... Bay Hangar KC-1󈧧R Aircraft and 137th Airlift Wing Relocation The United States Air Force has prepared three Environmental Assessments (EAs

Scheduling rules to achieve lead-time targets in outpatient appointment systems.

PubMed

Nguyen, Thu-Ba T; Sivakumar, Appa Iyer; Graves, Stephen C

2017-12-01

This paper considers how to schedule appointments for outpatients, for a clinic that is subject to appointment lead-time targets for both new and returning patients. We develop heuristic rules, which are the exact and relaxed appointment scheduling rules, to schedule each new patient appointment (only) in light of uncertainty about future arrivals. The scheduling rules entail two decisions. First, the rules need to determine whether or not a patient's request can be accepted; then, if the request is not rejected, the rules prescribe how to assign the patient to an available slot. The intent of the scheduling rules is to maximize the utilization of the planned resource (i.e., the physician staff), or equivalently to maximize the number of patients that are admitted, while maintaining the service targets on the median, the 95th percentile, and the maximum appointment lead-times. We test the proposed scheduling rules with numerical experiments using real data from the chosen clinic of Tan Tock Seng hospital in Singapore. The results show the efficiency and the efficacy of the scheduling rules, in terms of the service-target satisfaction and the resource utilization. From the sensitivity analysis, we find that the performance of the proposed scheduling rules is fairly robust to the specification of the established lead-time targets.

49 CFR 237.103 - Bridge inspection procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Bridge inspection procedures. 237.103 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.103 Bridge inspection procedures. (a) Each bridge management program shall specify the procedure to be used for...

49 CFR 237.55 - Railroad bridge supervisors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Railroad bridge supervisors. 237.55 Section 237.55..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Qualifications and Designations of Responsible Persons § 237.55 Railroad bridge supervisors. A railroad bridge supervisor shall be a person, regardless of...

48 CFR 237.7003 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... and contract clauses. 237.7003 Section 237.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING..., Permits. (8) 252.237-7011, Preparation History. (c) Use the clause at FAR 52.245-1, Government Property...

48 CFR 237.7003 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... and contract clauses. 237.7003 Section 237.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING..., Permits. (8) 252.237-7011, Preparation History. (c) Use the clause at FAR 52.245-1, Government Property...

48 CFR 237.7003 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... and contract clauses. 237.7003 Section 237.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING..., Permits. (8) 252.237-7011, Preparation History. (c) Use the clause at FAR 52.245-1, Government Property...

48 CFR 237.7003 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... and contract clauses. 237.7003 Section 237.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING..., Permits. (8) 252.237-7011, Preparation History. (c) Use the clause at FAR 52.245-1, Government Property...

48 CFR 237.7003 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... and contract clauses. 237.7003 Section 237.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING..., Permits. (8) 252.237-7011, Preparation History. (c) Use the clause at FAR 52.245-1, Government Property...

49 CFR 237.57 - Designations of individuals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Designations of individuals. 237.57 Section 237.57... § 237.57 Designations of individuals. Each track owner shall designate those individuals qualified as railroad bridge engineers, railroad bridge inspectors and railroad bridge supervisors. Each individual...

47 CFR 87.237 - Scope of service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Scope of service. 87.237 Section 87.237 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AVIATION SERVICES Aeronautical Multicom Stations § 87.237 Scope of service. (a) The communications of an aeronautical multicom...

49 CFR 237.151 - Audits; general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Audits; general. 237.151 Section 237.151..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Documentation, Records, and Audits of Bridge Management Programs § 237.151 Audits; general. Each program adopted to comply with this part shall include provisions...

49 CFR 237.55 - Railroad bridge supervisors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Railroad bridge supervisors. 237.55 Section 237.55..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Qualifications and Designations of Responsible Persons § 237.55 Railroad bridge supervisors. A railroad bridge supervisor shall be a person, regardless of...

49 CFR 237.103 - Bridge inspection procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Bridge inspection procedures. 237.103 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.103 Bridge inspection procedures. (a) Each bridge management program shall specify the procedure to be used for...

CABINS: A Framework of Knowledge Acquisition and Iterative Revision for Schedule Improvement and Reactive Repair

DTIC Science & Technology

1994-09-01

Aritificial Intelligence , pages 284-290, Los Angeles, CA, 1985 IJOAI 41 ADA2938 [KY89] Naiping Keng and David Y. Y. Yun. A plsaning/scheduling methodology for...of the 12th International Joint Conference on Artificial Intelligence (IJCAI-1.g), pages 218-224, S)dney, Australia, 1991. * Cha93j Alok &t Chaturvedi...National Conference an Artifi cial Intelligence , pages 49-54, Saint Paul, Minnesota, 1988. AAAI. [Fox83] Mark Fox. Constraint-Directed Seareh: A Case Study

49 CFR 237.53 - Railroad bridge inspectors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Railroad bridge inspectors. 237.53 Section 237.53..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Qualifications and Designations of Responsible Persons § 237.53 Railroad bridge inspectors. A railroad bridge inspector shall be a person who is determined by...

49 CFR 237.107 - Conduct of bridge inspections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Conduct of bridge inspections. 237.107 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.107 Conduct of bridge inspections. Bridge inspections shall be conducted under the direct supervision of a designated...

48 CFR 237.173 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Prohibition on interrogation of detainees by contractor personnel. 237.173 Section 237.173 Federal Acquisition Regulations... SERVICE CONTRACTING Service Contracts-General 237.173 Prohibition on interrogation of detainees by...

48 CFR 237.173 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Prohibition on interrogation of detainees by contractor personnel. 237.173 Section 237.173 Federal Acquisition Regulations... SERVICE CONTRACTING Service Contracts-General 237.173 Prohibition on interrogation of detainees by...

48 CFR 237.173 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Prohibition on interrogation of detainees by contractor personnel. 237.173 Section 237.173 Federal Acquisition Regulations... SERVICE CONTRACTING Service Contracts-General 237.173 Prohibition on interrogation of detainees by...

48 CFR 237.173 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Prohibition on interrogation of detainees by contractor personnel. 237.173 Section 237.173 Federal Acquisition Regulations... SERVICE CONTRACTING Service Contracts-General 237.173 Prohibition on interrogation of detainees by...

9 CFR 2.37 - Federal research facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Federal research facilities. 2.37 Section 2.37 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal...

1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ON RIGHT. (see also WV-237-5, WV-237-9, WV-237-h-1, WV-237-L-1) - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

49 CFR 237.155 - Documents and records.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Documentation, Records, and Audits of Bridge Management Programs § 237.155 Documents and records. Each track owner required to implement a bridge management... 49 Transportation 4 2012-10-01 2012-10-01 false Documents and records. 237.155 Section 237.155...

49 CFR 237.53 - Railroad bridge inspectors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Railroad bridge inspectors. 237.53 Section 237.53..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Qualifications and Designations of Responsible Persons § 237.53 Railroad bridge inspectors. A railroad bridge inspector shall be a person who is determined by...

49 CFR 237.107 - Conduct of bridge inspections.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Conduct of bridge inspections. 237.107 Section 237... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.107 Conduct of bridge inspections. Bridge inspections shall be conducted under the direct supervision of a designated...

The Synergistic Effect of Valsartan and LAF237 [(S)-1-[(3-Hydroxy-1-Adamantyl)Ammo]acetyl-2-Cyanopyrrolidine] on Vascular Oxidative Stress and Inflammation in Type 2 Diabetic Mice

PubMed Central

Shen, Min; Sun, Dongdong; Li, Weijie; Liu, Bing; Wang, Shenxu; Zhang, Zheng; Cao, Feng

2012-01-01

Aim. To investigate the combination effects and mechanisms of valsartan (angiotensin II type 1 receptor blocker) and LAF237 (DPP-IV inhibitor) on prevention against oxidative stress and inflammation injury in db/db mice aorta. Methods. Db/db mice (n = 40) were randomized to receive valsartan, LAF237, valsartan plus LAF237, or saline. Oxidative stress and inflammatory reaction in diabetic mice aorta were examined. Results. Valsartan or LAF237 pretreatment significantly increased plasma GLP-1 expression, reduced apoptosis of endothelial cells isolated from diabetic mice aorta. The expression of NAD(P)H oxidase subunits also significantly decreased resulting in decreased superoxide production and ICAM-1 (fold change: valsartan : 7.5 ± 0.7, P < 0.05; LAF237: 10.2 ± 1.7, P < 0.05), VCAM-1 (fold change: valsartan : 5.2 ± 1.2, P < 0.05; LAF237: 4.8 ± 0.6, P < 0.05), and MCP-1 (fold change: valsartan: 3.2 ± 0.6, LAF237: 4.7 ± 0.8; P < 0.05) expression. Moreover, the combination treatment with valsartan and LAF237 resulted in a more significant increase of GLP-1 expression. The decrease of the vascular oxidative stress and inflammation reaction was also higher than monotherapy with valsartan or LAF237. Conclusion. These data indicated that combination treatment with LAF237 and valsartan acts in a synergistic manner on vascular oxidative stress and inflammation in type 2 diabetic mice. PMID:22474415

49 CFR 237.109 - Bridge inspection records.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge management...

48 CFR 252.237-7010 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2014 CFR

2014-10-01

... interrogation of detainees by contractor personnel. 252.237-7010 Section 252.237-7010 Federal Acquisition... interrogation of detainees by contractor personnel. As prescribed in 237.173-5, use the following clause: Prohibition on Interrogation of Detainees by Contractor Personnel ((JUN 2013)) (a) Definitions. As used in...

48 CFR 252.237-7010 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2013 CFR

2013-10-01

... interrogation of detainees by contractor personnel. 252.237-7010 Section 252.237-7010 Federal Acquisition... interrogation of detainees by contractor personnel. As prescribed in 237.173-5, use the following clause: Prohibition on Interrogation of Detainees by Contractor Personnel ((JUN 2013)) (a) Definitions. As used in...

48 CFR 252.237-7003 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Requirements. 252.237-7003... Clauses 252.237-7003 Requirements. As prescribed in 237.7003(b), use the following clause: Requirements... from the Contractor all of its requirements in the area of performance for the supplies and services...

48 CFR 252.237-7003 - Requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requirements. 252.237-7003... Clauses 252.237-7003 Requirements. As prescribed in 237.7003(b), use the following clause: Requirements... from the Contractor all of its requirements in the area of performance for the supplies and services...

48 CFR 252.237-7003 - Requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requirements. 252.237-7003... Clauses 252.237-7003 Requirements. As prescribed in 237.7003(b), use the following clause: Requirements... from the Contractor all of its requirements in the area of performance for the supplies and services...

48 CFR 252.237-7003 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Requirements. 252.237-7003... Clauses 252.237-7003 Requirements. As prescribed in 237.7003(b), use the following clause: Requirements... from the Contractor all of its requirements in the area of performance for the supplies and services...

14 CFR 23.237 - Operation on water.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Operation on water. 23.237 Section 23.237... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 23.237 Operation on water. A wave height, demonstrated to be safe for operation, and any...

14 CFR 25.237 - Wind velocities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Wind velocities. 25.237 Section 25.237... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 25.237 Wind... wind velocity, demonstrated to be safe for takeoff and landing, must be established for dry runways and...

14 CFR 25.237 - Wind velocities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Wind velocities. 25.237 Section 25.237... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 25.237 Wind... wind velocity, demonstrated to be safe for takeoff and landing, must be established for dry runways and...

14 CFR 25.237 - Wind velocities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Wind velocities. 25.237 Section 25.237... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 25.237 Wind... wind velocity, demonstrated to be safe for takeoff and landing, must be established for dry runways and...

33 CFR 110.237 - Pacific Ocean at Waimea, Hawaii, Naval Anchorage.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Pacific Ocean at Waimea, Hawaii, Naval Anchorage. 110.237 Section 110.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.237 Pacific Ocean at Waimea...

33 CFR 110.237 - Pacific Ocean at Waimea, Hawaii, Naval Anchorage.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Pacific Ocean at Waimea, Hawaii, Naval Anchorage. 110.237 Section 110.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.237 Pacific Ocean at Waimea...

33 CFR 110.237 - Pacific Ocean at Waimea, Hawaii, Naval Anchorage.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Pacific Ocean at Waimea, Hawaii, Naval Anchorage. 110.237 Section 110.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.237 Pacific Ocean at Waimea...

48 CFR 52.237-2 - Protection of Government Buildings, Equipment, and Vegetation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Buildings, Equipment, and Vegetation. 52.237-2 Section 52.237-2 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.237-2 Protection of Government Buildings, Equipment, and Vegetation...: Protection of Government Buildings, Equipment, and Vegetation (APR 1984) The Contractor shall use reasonable...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

48 CFR 237.102 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy. 237.102 Section 237.102 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 237.102 Policy. (c) In addition to the prohibition on award of...

49 CFR 237.131 - Design.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Design. 237.131 Section 237.131 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS Repair and Modification of Bridges § 237.131 Design. Each repair or... component of a bridge shall be designed by a railroad bridge engineer. The design shall specify the manner...

7 CFR 959.237 - Assessment rate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Assessment rate. 959.237 Section 959.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Assessment Rates § 959.237 Assessment rate. On and after August 1, 2012, an assessment rate of $0.03 per 50...

7 CFR 959.237 - Assessment rate.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 8 2012-01-01 2012-01-01 false Assessment rate. 959.237 Section 959.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Assessment Rates § 959.237 Assessment rate. On and after August 1, 2009, an assessment rate of $0.025 per 50...

7 CFR 959.237 - Assessment rate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 8 2013-01-01 2013-01-01 false Assessment rate. 959.237 Section 959.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Assessment Rates § 959.237 Assessment rate. On and after August 1, 2009, an assessment rate of $0.025 per 50...

7 CFR 959.237 - Assessment rate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Assessment rate. 959.237 Section 959.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Assessment Rates § 959.237 Assessment rate. On and after August 1, 2009, an assessment rate of $0.025 per 50...

7 CFR 959.237 - Assessment rate.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Assessment rate. 959.237 Section 959.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Assessment Rates § 959.237 Assessment rate. On and after August 1, 2009, an assessment rate of $0.025 per 50...

49 CFR 238.237 - Automated monitoring.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Automated monitoring. 238.237 Section 238.237... Equipment § 238.237 Automated monitoring. (a) Except as further specified in this paragraph, on or after... train speed and capabilities of the signal system. The railroad shall document the basis for setting...

48 CFR 1852.237-72 - Access to Sensitive Information.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Access to Sensitive Information. 1852.237-72 Section 1852.237-72 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.237-72 Access to Sensitive Information. As prescribed in 1837.203-72(a), insert the...

32 CFR 237a.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Applicability. 237a.2 Section 237a.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PUBLIC AFFAIRS LIAISON WITH INDUSTRY § 237a.2 Applicability. The provisions of this part apply to all...

14 CFR 23.237 - Operation on water.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Operation on water. 23.237 Section 23.237... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 23.237 Operation on water. A wave height, demonstrated to be safe for operation, and any...

14 CFR 23.237 - Operation on water.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Operation on water. 23.237 Section 23.237... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 23.237 Operation on water. A wave height, demonstrated to be safe for operation, and any...

46 CFR 108.237 - Fuel storage facilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Fuel storage facilities. 108.237 Section 108.237... AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.237 Fuel storage facilities. (a) Helicopter fuel storage tanks must be installed as far as practicable from— (1) The landing area; and (2...

49 CFR 23.7 - Program reviews.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Program reviews. 23.7 Section 23.7 Transportation... CONCESSIONS General § 23.7 Program reviews. In 2010, and thereafter at the discretion of the Secretary, the Department will initiate a review of the ACDBE program to determine what, if any, modifications should be...

46 CFR 108.237 - Fuel storage facilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Fuel storage facilities. 108.237 Section 108.237... AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.237 Fuel storage facilities. (a) Helicopter fuel storage tanks must be installed as far as practicable from— (1) The landing area; and (2...

46 CFR 108.237 - Fuel storage facilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Fuel storage facilities. 108.237 Section 108.237... AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.237 Fuel storage facilities. (a) Helicopter fuel storage tanks must be installed as far as practicable from— (1) The landing area; and (2...

46 CFR 108.237 - Fuel storage facilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Fuel storage facilities. 108.237 Section 108.237... AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.237 Fuel storage facilities. (a) Helicopter fuel storage tanks must be installed as far as practicable from— (1) The landing area; and (2...

14 CFR 23.237 - Operation on water.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Operation on water. 23.237 Section 23.237... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 23.237 Operation on water. A wave height, demonstrated to be safe for operation, and any...

14 CFR 25.237 - Wind velocities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Wind velocities. 25.237 Section 25.237... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 25.237 Wind... wind velocity, demonstrated to be safe for takeoff and landing, must be established for dry runways and...

14 CFR 25.237 - Wind velocities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Wind velocities. 25.237 Section 25.237... STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Ground and Water Handling Characteristics § 25.237 Wind... wind velocity, demonstrated to be safe for takeoff and landing, must be established for dry runways and...

48 CFR 1252.237-70 - Qualifications of contractor employees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contractor employees. 1252.237-70 Section 1252.237-70 Federal Acquisition Regulations System DEPARTMENT OF....237-70 Qualifications of contractor employees. As prescribed in (TAR) 48 CFR 1237.110(a), insert the following clause: Qualifications of Contractor Employees (APR 2005) a. Definitions. As used in this clause...

49 CFR 237.109 - Bridge inspection records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Bridge inspection records. 237.109 Section 237.109..., DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.109 Bridge inspection records... performed on those bridges under this part. (b) Each record of an inspection under the bridge management...

34 CFR 237.8 - What definitions apply?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false What definitions apply? 237.8 Section 237.8 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION CHRISTA MCAULIFFE FELLOWSHIP PROGRAM General § 237.8 What definitions apply? (a) The...

34 CFR 237.8 - What definitions apply?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false What definitions apply? 237.8 Section 237.8 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION CHRISTA MCAULIFFE FELLOWSHIP PROGRAM General § 237.8 What definitions apply? (a) The...

34 CFR 237.7 - What regulations apply?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false What regulations apply? 237.7 Section 237.7 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION CHRISTA MCAULIFFE FELLOWSHIP PROGRAM General § 237.7 What regulations apply? The...

34 CFR 237.7 - What regulations apply?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false What regulations apply? 237.7 Section 237.7 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION CHRISTA MCAULIFFE FELLOWSHIP PROGRAM General § 237.7 What regulations apply? The...

49 CFR 237.7 - Penalties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Penalties. 237.7 Section 237.7 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.7 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

49 CFR 237.7 - Penalties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Penalties. 237.7 Section 237.7 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.7 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

49 CFR 237.7 - Penalties.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Penalties. 237.7 Section 237.7 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.7 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

49 CFR 237.7 - Penalties.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Penalties. 237.7 Section 237.7 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.7 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

49 CFR 237.7 - Penalties.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Penalties. 237.7 Section 237.7 Transportation... TRANSPORTATION BRIDGE SAFETY STANDARDS General § 237.7 Penalties. (a) Any person who violates any requirement of this part or causes the violation of any such requirement is subject to a civil penalty of at least...

Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans

PubMed Central

Sabourin, Carol L.; Schiffer, Jarad M.; Niemuth, Nancy A.; Semenova, Vera A.; Li, Han; Rudge, Thomas L.; Brys, April M.; Mittler, Robert S.; Ibegbu, Chris C.; Wrammert, Jens; Ahmed, Rafi; Parker, Scott D.; Babcock, Janiine; Keitel, Wendy; Poland, Gregory A.; Keyserling, Harry L.; El Sahly, Hana; Jacobson, Robert M.; Marano, Nina; Plikaytis, Brian D.; Wright, Jennifer G.

2016-01-01

Protective antigen (PA)-specific antibody and cell-mediated immune (CMI) responses to annual and alternate booster schedules of anthrax vaccine adsorbed (AVA; BioThrax) were characterized in humans over 43 months. Study participants received 1 of 6 vaccination schedules: a 3-dose intramuscular (IM) priming series (0, 1, and 6 months) with a single booster at 42 months (4-IM); 3-dose IM priming with boosters at 18 and 42 months (5-IM); 3-dose IM priming with boosters at 12, 18, 30, and 42 months (7-IM); the 1970 licensed priming series of 6 doses (0, 0.5, 1, 6, 12, and 18 months) and two annual boosters (30 and 42 months) administered either subcutaneously (SQ) (8-SQ) or IM (8-IM); or saline placebo control at all eight time points. Antibody response profiles included serum anti-PA IgG levels, subclass distributions, avidity, and lethal toxin neutralization activity (TNA). CMI profiles included frequencies of gamma interferon (IFN-γ)- and interleukin 4 (IL-4)-secreting cells and memory B cells (MBCs), lymphocyte stimulation indices (SI), and induction of IFN-γ, IL-2, IL-4, IL-6, IL-1β, and tumor necrosis factor alpha (TNF-α) mRNA. All active schedules elicited high-avidity PA-specific IgG, TNA, MBCs, and T cell responses with a mixed Th1-Th2 profile and Th2 dominance. Anti-PA IgG and TNA were highly correlated (e.g., month 7, r2 = 0.86, P < 0.0001, log10 transformed) and declined in the absence of boosters. Boosters administered IM generated the highest antibody responses. Increasing time intervals between boosters generated antibody responses that were faster than and superior to those obtained with the final month 42 vaccination. CMI responses to the 3-dose IM priming remained elevated up to 43 months. (This study has been registered at ClinicalTrials.gov under registration no. NCT00119067.) PMID:26865594

77 FR 10575 - National Science Board; Sunshine Act Meetings; Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

... 9th and N. Stuart Streets entrance on the day of the teleconference to receive a visitor's badge... additional information and schedule updates (time, place, subject matter or status of meeting) may be found...

KSC-2011-1628

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1630

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

KSC-2011-1627

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here, is State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

48 CFR 352.237-71 - Crime Control Act-reporting of child abuse.

Code of Federal Regulations, 2010 CFR

2010-10-01

... mental injury, sexual abuse or exploitation, or negligent treatment of a child. (c) Accordingly, any...-reporting of child abuse. 352.237-71 Section 352.237-71 Federal Acquisition Regulations System HEALTH AND... Clauses 352.237-71 Crime Control Act—reporting of child abuse. As prescribed in 337.103-70(b), the...

32 CFR 237a.3 - Objective and policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Objective and policy. 237a.3 Section 237a.3...) MISCELLANEOUS PUBLIC AFFAIRS LIAISON WITH INDUSTRY § 237a.3 Objective and policy. (a) It is important that... subchapter, DoD components shall cooperate with industry at local and regional levels. However, they will...

48 CFR 252.237-7010 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2012 CFR

2012-10-01

... interrogation of detainees by contractor personnel. 252.237-7010 Section 252.237-7010 Federal Acquisition... interrogation of detainees by contractor personnel. As prescribed in 237.173-5, use the following clause: Prohibition on Interrogation of Detainees by Contractor Personnel (NOV 2010) (a) Definitions. As used in this...

48 CFR 252.237-7010 - Prohibition on interrogation of detainees by contractor personnel.

Code of Federal Regulations, 2011 CFR

2011-10-01

... interrogation of detainees by contractor personnel. 252.237-7010 Section 252.237-7010 Federal Acquisition... interrogation of detainees by contractor personnel. As prescribed in 237.173-5, use the following clause: PROHIBITION ON INTERROGATION OF DETAINEES BY CONTRACTOR PERSONNEL (NOV 2010) (a) Definitions. As used in this...

48 CFR 252.237-7008 - Group interment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Group interment. 252.237... Clauses 252.237-7008 Group interment. As prescribed in 237.7003(b), use the following clause: Group... interred as a group on the basis of the number of caskets furnished, rather than on the basis of the number...

48 CFR 252.237-7008 - Group interment.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Group interment. 252.237... Clauses 252.237-7008 Group interment. As prescribed in 237.7003(b), use the following clause: Group... interred as a group on the basis of the number of caskets furnished, rather than on the basis of the number...

48 CFR 252.237-7008 - Group interment.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Group interment. 252.237... Clauses 252.237-7008 Group interment. As prescribed in 237.7003(b), use the following clause: Group... interred as a group on the basis of the number of caskets furnished, rather than on the basis of the number...

48 CFR 252.237-7008 - Group interment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Group interment. 252.237... Clauses 252.237-7008 Group interment. As prescribed in 237.7003(b), use the following clause: Group... interred as a group on the basis of the number of caskets furnished, rather than on the basis of the number...

49 CFR 1544.237 - Flight deck privileges.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 9 2011-10-01 2011-10-01 false Flight deck privileges. 1544.237 Section 1544.237... COMMERCIAL OPERATORS Operations § 1544.237 Flight deck privileges. (a) For each aircraft that has a door to the flight deck, each aircraft operator must restrict access to the flight deck as provided in its...

49 CFR 1544.237 - Flight deck privileges.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 9 2013-10-01 2013-10-01 false Flight deck privileges. 1544.237 Section 1544.237... COMMERCIAL OPERATORS Operations § 1544.237 Flight deck privileges. (a) For each aircraft that has a door to the flight deck, each aircraft operator must restrict access to the flight deck as provided in its...

49 CFR 1544.237 - Flight deck privileges.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 9 2012-10-01 2012-10-01 false Flight deck privileges. 1544.237 Section 1544.237... COMMERCIAL OPERATORS Operations § 1544.237 Flight deck privileges. (a) For each aircraft that has a door to the flight deck, each aircraft operator must restrict access to the flight deck as provided in its...

49 CFR 1544.237 - Flight deck privileges.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 9 2014-10-01 2014-10-01 false Flight deck privileges. 1544.237 Section 1544.237... COMMERCIAL OPERATORS Operations § 1544.237 Flight deck privileges. (a) For each aircraft that has a door to the flight deck, each aircraft operator must restrict access to the flight deck as provided in its...

49 CFR 1544.237 - Flight deck privileges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Flight deck privileges. 1544.237 Section 1544.237... COMMERCIAL OPERATORS Operations § 1544.237 Flight deck privileges. (a) For each aircraft that has a door to the flight deck, each aircraft operator must restrict access to the flight deck as provided in its...

48 CFR 52.237-11 - Accepting and Dispensing of $1 Coin.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of $1 Coin. 52.237-11 Section 52.237-11 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.237-11 Accepting and Dispensing of $1 Coin. As prescribed in 37.116-2, insert the following clause: Accepting and Dispensing of $1 Coin (SEP 2008) (a) This clause applies to service contracts that...

48 CFR 52.237-11 - Accepting and Dispensing of $1 Coin.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of $1 Coin. 52.237-11 Section 52.237-11 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.237-11 Accepting and Dispensing of $1 Coin. As prescribed in 37.116-2, insert the following clause: Accepting and Dispensing of $1 Coin (SEP 2008) (a) This clause applies to service contracts that...

48 CFR 552.237-72 - Prohibition Regarding “Quasi-Military Armed Forces.”

Code of Federal Regulations, 2010 CFR

2010-10-01

...Quasi-Military Armed Forces.â 552.237-72 Section 552.237-72 Federal Acquisition Regulations System... Provisions and Clauses 552.237-72 Prohibition Regarding “Quasi-Military Armed Forces.” As prescribed in 537.110(b), insert the following clause: Prohibition Regarding “Quasi-Military Armed Forces” (SEP 1999...

48 CFR 252.237-7008 - Group interment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Group interment. 252.237... Clauses 252.237-7008 Group interment. As prescribed in 237.7003(b), use the following clause: Group... interred as a group on the basis of the number of caskets furnished, rather than on the basis of the number...

48 CFR 2452.237-73 - Conduct of Work and Technical Guidance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... conditions of the contract. (c) The GTR will issue technical guidance in writing or, if issued orally, he/she... Technical Guidance. 2452.237-73 Section 2452.237-73 Federal Acquisition Regulations System DEPARTMENT OF... Provisions and Clauses 2452.237-73 Conduct of Work and Technical Guidance. As prescribed in 2437.110(d...

48 CFR 1352.237-70 - Security processing requirements-high or moderate risk contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirements-high or moderate risk contracts. 1352.237-70 Section 1352.237-70 Federal Acquisition Regulations... Provisions and Clauses 1352.237-70 Security processing requirements—high or moderate risk contracts. As prescribed in 48 CFR 1337.110-70 (b), insert the following clause: Security Processing Requirements—High or...

Defense Acquisition Research Journal. Volume 19, Number 1, Issue 61, January 2012

DTIC Science & Technology

2012-01-01

format (author-date-page number form of citation) as outlined in the Publication Manual of the American Psycho- logical Association ( 6th Edition ). For all...other style questions, please refer to the Chicago Manual of Style (15th Edition ). Contributors are encouraged to seek the advice of a reference...theme editions . Please consult the DAU home page for current themes being solicited. See print schedule below. 2012 Due Date Publication Date July 1

KSC-06pd2091

NASA Image and Video Library

2006-09-09

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Mission Specialist Joseph Tanner dons his launch and re-entry suit before heading to the launch pad for another attempt at liftoff. The launch attempt on Sept. 8 was scrubbed due to an issue with a fuel cut-off sensor system inside the external fuel tank. This is one of several systems that protect the shuttle's main engines by triggering their shutdown if fuel runs unexpectedly low. Liftoff today is scheduled for 11:15 a.m. EDT. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

KSC-2011-1684

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- CAPE CANAVERAL, Fla. -- NASA Kennedy Space Center Director Robert Cabana, right, explains the operations taking place at Florida's space center to House Of Representatives Democratic Leader Nancy Pelosi, from California's 8th District, fourth from left, and other VIPs. They are at Florida's space center to witness space shuttle Discovery make history as it lifts off on its final scheduled mission from Launch Pad 39A. While at the center, they attended a presentation in the Operations Support Building II and toured Orbiter Processing Facilities 1 and 2 where shuttles Atlantis and Endeavour are being prepared for their final missions respectively. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery will make its 39th mission and is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the...

KSC-02pp1818

NASA Image and Video Library

2002-11-23

KENNEDY SPACE CENTER, FLA. - Blue mach diamonds appear behind the main engine nozzles on Space Shuttle Endeavour as it roars off the launch pad on mission STS-113. Liftoff from Launch Pad 39A occurred ontime at 7:49:47 p.m. EST. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Also onboard are the Expedition 6 crew, who will replace Expedition 5. Endeavour is scheduled to land at KSC after an 11-day journey.

STS-113 Space Shuttle Endeavour launch

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. - Water near Launch Pad 39A provides a mirror image of Space Shuttle Endeavour blazing a path into the night sky after launch on mission STS-113. Liftoff occurred ontime at 7:49:47 p.m. EST. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Also onboard are the Expedition 6 crew, who will replace Expedition 5. Endeavour is scheduled to land at KSC after an 11-day journey.

Characteristics of North Korea nuclear test and KMA magnitude scale

NASA Astrophysics Data System (ADS)

Jeon, Y. S.; Lee, D.; Min, K.; Hwang, E. H.; Lee, J.; Park, E.; Jo, E.; Lee, M. S.

2017-12-01

Democratic People's Republic of Korea(DPRK) carried out 6th nuclear test on 3 Sep. 2017 at 03:30 UTC. Korea Meteorological Administration(KMA) announced to the public that the event took place in the DPRK's test site, Punggye-ri with the magnitude 5.7. This event is larger than previous one in terms of magnitude and showed that measured magnitude strongly depends on the frequency band of data. After we applied several magnitude scales such as Everdon(1967), Nuttli(1967), and Hong & Lee(2012) to this event, we found that magnitude ranges from 5.3 to 6.7 which depends on frequency band and epicentral distance of signal. 6th DPRK test experiment indicated that spectral amplitude ratio of 6th/5th near 2.37 Hz shows similar amplification compatible to relative spectral magnitude 5.7, while spectral amplitude ratio of 6th/5th near 1.0 Hz marks relative spectral magnitude about 6.1. Relative spectral magnitude varies with frequencies and decreases as frequency increase. We found that systematic non-linearity exists for spectral amplitude ratio of 6th/5th from 1.0 to 10.0 Hz, while it's characteristic is not found at 5th/4th and 4th/3th. A methodology is presented for determining mb(Pn) magnitude of underground nuclear explosions from local Pn phase. 582 waveforms from vertical component of broadband and acceleration seismographs at 120 stations in the epicenter distance from 340 to 800 km are used to calibrate mb(Pn) magnitude scaling for DPRK's nuclear tests. The mb(Pn) estimates of regional events for Korean Peninsula are determined to be mb(Pn) ? = log10(A) + 2.1164×log10(d) - 0.2721, where A is the peak-to-peak Pn amplitude in μm and d is the epicentral distance in km. Systematic non-linearity does not observed at frequency band from 0.1 to 1.0 Hz. The magnitude of 6th event is mb(Pn) 6.08 and mb(Pn) 4.52, 4.92, 4.84 and 5.03 for 2nd, 3rd, 4th and 5th respectively. Further research of applicable mb(Pn) magnitude scaling is required for all frequency band and epicentral distance rage using KMA seismic data.

Separation of actinides using capillary extraction chromatography-inductively coupled plasma mass spectrometry.

PubMed

Peterson, Dominic S; Montoya, Velma M

2009-08-01

Trace levels of actinides have been separated on capillary extraction chromatography columns. Detection of the actinides was achieved using an inductively coupled plasma mass spectrometer, which was coupled with the extraction chromatography system. In this study, we compare 30-cm long, 4.6 mm i.d. columns to capillary columns (750 microm i.d.) with lengths from 30 cm up to 150 cm. The columns that were tested were packed with TRU resin. We were able to separate a mixture of five actinides ((232)Th, (238)U, (237)Np, (239)Pu, and (241)Am). This work has application to rapid bioassay as well as automated separations of actinide materials.

15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Notice to Department of Commerce organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the Secretary of Commerce USE OF PENALTY MAIL IN THE LOCATION AND RECOVERY OF MISSING CHILDREN § 23.7 Notice to...

The effect of tramadol plus paracetamol on consumption of morphine after coronary artery bypass grafting.

PubMed

Altun, Dilek; Çınar, Özlem; Özker, Emre; Türköz, Ayda

2017-02-01

To compare the effects of oral tramadol+paracetamol combination on morphine consumption following coronary artery bypass grafting (CABG) in the patient-controlled analgesia (PCA) protocol. A prospective, double-blind, randomized, clinical study. Single-institution, tertiary hospital. Fifty cardiac surgical patients undergoing primary CABG surgery. After surgery, the patients were allocated to 1 of 2 groups. Both groups received morphine according to the PCA protocol after arrival to the coronary intensive care unit (bolus 1 mg, lockout time 15 minutes). In addition to morphine administration 2 hours before operation and postoperative 2nd, 6th, 12th, 18th, 24th, 30th, 36th, 42th, and 48th hours, group T received tramadol+paracetamol (Zaldiar; 325 mg paracetamol, 37.5 mg tramadol) and group P received placebo. Sedation levels were measured with the Ramsay Sedation Scale, whereas pain was assessed with the Pain Intensity Score during mechanical ventilation and with the Numeric Rating Scale after extubation. If the Numeric Rating Scale score was ≥3 and Pain Intensity Score was ≥3, 0.05 mg/kg morphine was administered additionally. Preoperative patient characteristics, risk assessment, and intraoperative data were similar between the groups. Cumulative morphine consumption, number of PCA demand, and boluses were higher in group P (P<.01). The amount of total morphine (in mg) used as a rescue analgesia was also higher in group P (5.06±1.0), compared with group T (2.37±0.52; P<.001). The patients who received rescue doses of morphine were 8 (32%) in group T and 18 (72%) in group P (P<.001). Duration of mechanical ventilation in group P was longer than group T (P<.01). Tramadol+paracetamol combination along with PCA morphine improves analgesia and reduces morphine requirement up to 50% after CABG, compared with morphine PCA alone. Copyright © 2016 Elsevier Inc. All rights reserved.

Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study.

PubMed

Kokaze, Akatsuki; Ishikawa, Mamoru; Matsunaga, Naomi; Karita, Kanae; Yoshida, Masao; Ohtsu, Tadahiro; Ochiai, Hirotaka; Shirasawa, Takako; Nanri, Hinako; Hoshino, Hiromi; Takashima, Yutaka

2013-11-20

NADH dehydrogenase subunit-2 237 leucine/methionine (ND2-237 Leu/Met) polymorphism is associated with longevity in Japanese. A previous study has shown that ND2-237 Leu/Met polymorphism modulates the effects of green tea consumption on risk of hypertension. For men with ND2-237Leu, habitual green tea consumption may reduce the risk of hypertension. Moreover, there is a combined effect of ND2-237 Leu/Met polymorphism and alcohol consumption on risk of mildly decreased estimated glomerular filtration rate (eGFR) (<90 ml/min/1.73 m2). Several beneficial effects of green tea on the kidney have been reported. The objective of this study was to investigate whether ND2-237 Leu/Met polymorphism modifies the effects of green tea consumption on risk of mildly decreased eGFR in male Japanese health check-up examinees. For ND2-237Leu genotypic men, after adjustment for confounding factors, green tea consumption may increase the risk of mildly decreased eGFR (P for trend = 0.016). The adjusted odds ratio (OR) for mildly decreased eGFR was significantly higher in subjects with ND2-237Leu who consume ≥6 cups of green tea per day than those who consume ≤1 cup of green tea per day (adjusted OR = 5.647, 95% confidence interval: 1.528-20.88, P = 0.009). On the other hand, for ND2-237Met genotypic men, green tea consumption does not appear to determine the risk of mildly decreased eGFR. The present results suggest that ND2-237 Leu/Met polymorphism unexpectedly modifies the effects of green tea consumption on eGFR and the risk of mildly decreased eGFR in male Japanese subjects.

Unexpected combined effects of NADH dehydrogenase subunit-2 237 Leu/Met polymorphism and green tea consumption on renal function in male Japanese health check-up examinees: a cross-sectional study

PubMed Central

2013-01-01

Background NADH dehydrogenase subunit-2 237 leucine/methionine (ND2-237 Leu/Met) polymorphism is associated with longevity in Japanese. A previous study has shown that ND2-237 Leu/Met polymorphism modulates the effects of green tea consumption on risk of hypertension. For men with ND2-237Leu, habitual green tea consumption may reduce the risk of hypertension. Moreover, there is a combined effect of ND2-237 Leu/Met polymorphism and alcohol consumption on risk of mildly decreased estimated glomerular filtration rate (eGFR) (<90 ml/min/1.73 m2). Several beneficial effects of green tea on the kidney have been reported. The objective of this study was to investigate whether ND2-237 Leu/Met polymorphism modifies the effects of green tea consumption on risk of mildly decreased eGFR in male Japanese health check-up examinees. Results For ND2-237Leu genotypic men, after adjustment for confounding factors, green tea consumption may increase the risk of mildly decreased eGFR (P for trend = 0.016). The adjusted odds ratio (OR) for mildly decreased eGFR was significantly higher in subjects with ND2-237Leu who consume ≥6 cups of green tea per day than those who consume ≤1 cup of green tea per day (adjusted OR = 5.647, 95% confidence interval: 1.528-20.88, P = 0.009). On the other hand, for ND2-237Met genotypic men, green tea consumption does not appear to determine the risk of mildly decreased eGFR. Conclusion The present results suggest that ND2-237 Leu/Met polymorphism unexpectedly modifies the effects of green tea consumption on eGFR and the risk of mildly decreased eGFR in male Japanese subjects. PMID:24252463

78 FR 9451 - Academy Express, L.L.C.-Acquisition of Property-Golden Ring Travel & Transportation, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-08

... decision can be made on the record as developed, a procedural schedule will be adopted to reconsider the... Justice, Antitrust Division, 10th Street & Pennsylvania Avenue NW., Washington, DC 20530; and (3) the U.S...

7 CFR 1209.237 - Appointment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Appointment. 1209.237 Section 1209.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.237 - Appointment.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Appointment. 1209.237 Section 1209.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.237 - Appointment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Appointment. 1209.237 Section 1209.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.237 - Appointment.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Appointment. 1209.237 Section 1209.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

7 CFR 1209.237 - Appointment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Appointment. 1209.237 Section 1209.237 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND...

DDC19: An Indictment.

ERIC Educational Resources Information Center

Berman, Sanford

1980-01-01

Criticizes the 19th edition of "Dewey Decimal Classification" for violating traditional classification goals for library materials and ignoring the desires of libraries and other users. A total reform is proposed to eliminate Phoenix schedules and to accept only those relocations approved by an editorial board of users. (RAA)

14 CFR 298.21 - Filing for registration by air taxi operators.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ambulance operations, firefighting or seasonal operations); 7 Companies proposing to provide scheduled... conduct such operations under their air taxi registration; such companies must first be found fit, willing... Region Headquarters (AAL-230), 222 West 7th Avenue, Box 14, Anchorage, Alaska 99513. ...

KSC-2011-1629

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. -- Folks from across the country camped out in communities surrounding NASA's Kennedy Space Center in Florida to witness space shuttle Discovery make history by lifting off on its final scheduled mission from Launch Pad 39A. Seen here is Sand Point Park near U. S. Highway 1 and State Road 406, also known as the A. Max Brewer Causeway, in Titusville, Fla. Liftoff is set for 4:50 p.m. EST on Feb. 24. Discovery and its six-member STS-133 crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jack Pfaller

OPTIMIZATION OF MUD HAMMER DRILLING PERFORMANCE - A PROGRAM TO BENCHMARK THE VIABILITY OF ADVANCED MUD HAMMER DRILLING

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gordon Tibbitts; Arnis Judzis

2001-04-01

This document details the progress to date on the OPTIMIZATION OF MUD HAMMER DRILLING PERFORMANCE -- A PROGRAM TO BENCHMARK THE VIABILITY OF ADVANCED MUD HAMMER DRILLING contract for the quarter starting January 2001 through March 2001. Accomplishments to date include the following: (1) On January 9th of 2001, details of the Mud Hammer Drilling Performance Testing Project were presented at a ''kick-off'' meeting held in Morgantown. (2) A preliminary test program was formulated and prepared for presentation at a meeting of the advisory board in Houston on the 8th of February. (3) The meeting was held with the advisorymore » board reviewing the test program in detail. (4) Consensus was achieved and the approved test program was initiated after thorough discussion. (5) This new program outlined the details of the drilling tests as well as scheduling the test program for the weeks of 14th and 21st of May 2001. (6) All the tasks were initiated for a completion to coincide with the test schedule. (7) By the end of March the hardware had been designed and the majority was either being fabricated or completed. (8) The rock was received and cored into cylinders.« less

Probing the dynamic interface between trimethylamine dehydrogenase (TMADH) and electron transferring flavoprotein (ETF) in the TMADH-2ETF complex: role of the Arg-alpha237 (ETF) and Tyr-442 (TMADH) residue pair.

PubMed

Burgess, Selena G; Messiha, Hanan Latif; Katona, Gergely; Rigby, Stephen E J; Leys, David; Scrutton, Nigel S

2008-05-06

We have used multiple solution state techniques and crystallographic analysis to investigate the importance of a putative transient interaction formed between Arg-alpha237 in electron transferring flavoprotein (ETF) and Tyr-442 in trimethylamine dehydrogenase (TMADH) in complex assembly, electron transfer, and structural imprinting of ETF by TMADH. We have isolated four mutant forms of ETF altered in the identity of the residue at position 237 (alphaR237A, alphaR237K, alphaR237C, and alphaR237E) and with each form studied electron transfer from TMADH to ETF, investigated the reduction potentials of the bound ETF cofactor, and analyzed complex formation. We show that mutation of Arg-alpha237 substantially destabilizes the semiquinone couple of the bound FAD and impedes electron transfer from TMADH to ETF. Crystallographic structures of the mutant ETF proteins indicate that mutation does not perturb the overall structure of ETF, but leads to disruption of an electrostatic network at an ETF domain boundary that likely affects the dynamic properties of ETF in the crystal and in solution. We show that Arg-alpha237 is required for TMADH to structurally imprint the as-purified semiquinone form of wild-type ETF and that the ability of TMADH to facilitate this structural reorganization is lost following (i) redox cycling of ETF, or simple conversion to the oxidized form, and (ii) mutagenesis of Arg-alpha237. We discuss this result in light of recent apparent conflict in the literature relating to the structural imprinting of wild-type ETF. Our studies support a mechanism of electron transfer by conformational sampling as advanced from our previous analysis of the crystal structure of the TMADH-2ETF complex [Leys, D. , Basran, J. , Sutcliffe, M. J., and Scrutton, N. S. (2003) Nature Struct. Biol. 10, 219-225] and point to a key role for the Tyr-442 (TMADH) and Arg-alpha237 (ETF) residue pair in transiently stabilizing productive electron transfer configurations. Our work also points to the importance of Arg-alpha237 in controlling the thermodynamics of electron transfer, the dynamics of ETF, and the protection of reducing equivalents following disassembly of the TMADH-2ETF complex.

47 CFR 15.237 - Operation in the bands 72.0-73.0 MHz, 74.6-74.8 MHz and 75.2-76.0 MHz.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Operation in the bands 72.0-73.0 MHz, 74.6-74.8 MHz and 75.2-76.0 MHz. 15.237 Section 15.237 Telecommunication FEDERAL COMMUNICATIONS COMMISSION....237 Operation in the bands 72.0-73.0 MHz, 74.6-74.8 MHz and 75.2-76.0 MHz. (a) The intentional...

Analysis of trace neptunium in the vicinity of underground nuclear tests at the Nevada National Security Site

DOE PAGES

Zhao, P.; Tinnacher, R. M.; Zavarin, M.; ...

2014-11-01

A high sensitivity analytical method for 237Np analysis was developed and applied to groundwater samples from the Nevada National Security Site (NNSS) using short-lived 239Np as a yield tracer and HR magnetic sector ICP-MS. The 237Np concentrations in the vicinity of the Almendro, Cambric, Dalhart, Cheshire, and Chancellor underground nuclear test locations range from <4 × 10 -4 to 2.6 mBq/L (6 × 10 -17–4.2 × 10 -13 mol/L). All measured 237Np concentrations are well below the drinking water maximum contaminant level for alpha emitters identified by the U.S. EPA (560 mBq/L). Nevertheless, 237Np remains an important indicator for radionuclidemore » transport rates at the NNSS. Retardation factor ratios were used to compare the mobility of 237Np to that of other radionuclides. The results suggest that 237Np is less mobile than tritium and other non-sorbing radionuclides ( 14C, 36Cl, 99Tc and 129I) as expected. Surprisingly, 237Np and plutonium ( 239,240Pu) retardation factors are very similar. It is possible that Np(IV) exists under mildly reducing groundwater conditions and exhibits a retardation behavior that is comparable to Pu(IV). Independent of the underlying process, 237Np is migrating downgradient from NNSS underground nuclear tests at very low but measureable concentrations.« less

The microtubule-active antitumor compound TTI-237 has both paclitaxel-like and vincristine-like properties.

PubMed

Beyer, Carl F; Zhang, Nan; Hernandez, Richard; Vitale, Danielle; Nguyen, Thai; Ayral-Kaloustian, Semiramis; Gibbons, James J

2009-09-01

To compare TTI-237 (5-chloro-6-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-[1, 2, 4]triazolo[1,5-a]pyrimidin-7-amine butanedioate) with paclitaxel and vincristine in order to better understand the properties of this new anti-microtubule agent. Tubulin polymerization and depolymerization were followed by turbidimetric assays. Effects of compounds on the binding of [(3)H]guanosine triphosphate ([(3)H]GTP) to tubulin were studied by competition binding assays. Effects of compounds on the phosphorylation of a panel of intracellular proteins were determined by flow cytometry using phosphoprotein-specific antibodies. At low molar ratios of TTI-237:tubulin heterodimer (about 1:30), TTI-237 enhanced depolymerization kinetics in response to low temperature, but stabilized the aggregates at higher ratios (about 1:4). Similarly, the aggregates induced in microtubule protein by TTI-237 were depolymerized by excess Ca(++) at low TTI-237:tubulin-heterodimer molar ratios, but were stable at higher ratios. TTI-237 inhibited the exchange of [(3)H]GTP at the exchangeable nucleotide site of the tubulin heterodimer, and was similar to vincristine in its effects on the phosphorylation of eight intracellular proteins in HeLa cells. TTI-237 has properties that distinguish it from typical vinca-site and taxoid-site ligands, and therefore it may exemplify a new class of microtubule-active compounds.

33 CFR 136.237 - Authorized claimants.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Authorized claimants. 136.237 Section 136.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.237 - Authorized claimants.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Authorized claimants. 136.237 Section 136.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.237 - Authorized claimants.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Authorized claimants. 136.237 Section 136.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.237 - Authorized claimants.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Authorized claimants. 136.237 Section 136.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.237 - Authorized claimants.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorized claimants. 136.237 Section 136.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

Potential Fifty Percent Reduction in Saturation Diving Decompression Time Using a Combination of Intermittent Recompression and Exercise

NASA Technical Reports Server (NTRS)

Gernhardt, Michael I.; Abercromby, Andrew; Conklin, Johnny

2007-01-01

Conventional saturation decompression protocols use linear decompression rates that become progressively slower at shallower depths, consistent with free gas phase control vs. dissolved gas elimination kinetics. If decompression is limited by control of free gas phase, linear decompression is an inefficient strategy. The NASA prebreathe reduction program demonstrated that exercise during O2 prebreathe resulted in a 50% reduction (2 h vs. 4 h) in the saturation decompression time from 14.7 to 4.3 psi and a significant reduction in decompression sickness (DCS: 0 vs. 23.7%). Combining exercise with intermittent recompression, which controls gas phase growth and eliminates supersaturation before exercising, may enable more efficient saturation decompression schedules. A tissue bubble dynamics model (TBDM) was used in conjunction with a NASA exercise prebreathe model (NEPM) that relates tissue inert gas exchange rate constants to exercise (ml O2/kg-min), to develop a schedule for decompression from helium saturation at 400 fsw. The models provide significant prediction (p < 0.001) and goodness of fit with 430 cases of DCS in 6437 laboratory dives for TBDM (p = 0.77) and with 22 cases of DCS in 159 altitude exposures for NEPM (p = 0.70). The models have also been used operationally in over 25,000 dives (TBDM) and 40 spacewalks (NEPM). The standard U.S. Navy (USN) linear saturation decompression schedule from saturation at 400 fsw required 114.5 h with a maximum Bubble Growth Index (BGI(sub max)) of 17.5. Decompression using intermittent recompression combined with two 10 min exercise periods (75% VO2 (sub peak)) per day required 54.25 h (BGI(sub max): 14.7). Combined intermittent recompression and exercise resulted in a theoretical 53% (2.5 day) reduction in decompression time and theoretically lower DCS risk compared to the standard USN decompression schedule. These results warrant future decompression trials to evaluate the efficacy of this approach.

Natural radioelement concentrations in the soil of the Mila region of Algeria

NASA Astrophysics Data System (ADS)

Bramki, Amina; Ramdhane, Mourad; Benrachi, Fatima

2017-09-01

In this study, the levels of the natural and artificial radioactivity in soil samples collected at various depths from Algerian agricultural region El-Athmania Mila was measured. Activity concentrations of the concerned radionuclides were determined by gamma-ray spectrometry using a high-purity germanium detector. The activity concentrations of 226Ra, 232Th and 40K were found unchanged as a function of depth and ranged from 23.72±2.37to 65.47±5.06 Bq.kg-1 for 226Ra, from 26.45±0.78 to 27.10±0.80 Bq.kg-1 for 232Th and from 220.80±10.01 to 260.70±8.24 Bq.kg-1 for 40K respectively. To evaluate the radiological hazard of radioactivity in samples, the radium equivalent activity (Raeq), the absorbed dose rate (D), the annual effective dose and the external (Hex) and internal hazard indices (Hin) were calculated. The mean of the excess lifetime cancer risk observed in this study are under the world's mean values.

Job expansion : an additional benefit of a computer aided dispatch/automatic vehicle locator (CAD/AVL) system

DOT National Transportation Integrated Search

2000-03-01

The Denver Regional Transportation District (RTD) acquired a CAD/AVL system that became fully operational in 1996. The CAD/AVL system added radio channels and covert alarms in buses, located vehicles in real time, and monitored schedule adherence. Th...

Toward Realistic Acquisition Schedule Estimates

DTIC Science & Technology

2016-04-30

Harrier successor. NASA and the UK both participated in this effort. It was merged by Congress with JAST in mid-1994.  CALF (Common Affordable...5th Generation revolution in military aviation. Space Daily. Sternstein, A. (2015, April 27). Here’s how you hack a military drone. Next Gov

237Np analytical method using 239Np tracers and application to a contaminated nuclear disposal facility

DOE PAGES

Snow, Mathew S.; Morrison, Samuel S.; Clark, Sue B.; ...

2017-03-21

In this study, environmental 237Np analyses are challenged by low 237Np concentrations and lack of an available yield tracer; we report a rapid, inexpensive 237Np analytical approach employing the short lived 239Np (t1/2 = 2.3 days) as a chemical yield tracer followed by 237Np quantification using inductively coupled plasma-mass spectrometry. 239Np tracer is obtained via separation from a 243Am stock solution and standardized using gamma spectrometry immediately prior to sample processing. Rapid digestions using a commercial, 900 W "Walmart" microwave and Parr microwave vessels result in 99.8 ± 0.1% digestion yields, while chromatographic separations enable Np/U separation factors on themore » order of 10 6 and total Np yields of 95 ± 4% (2σ). Application of this method to legacy soil samples surrounding a radioactive disposal facility (the Subsurface Disposal Area at Idaho National Laboratory) reveal the presence of low level 237Np contamination within 600 m of this site, with maximum 237Np concentrations on the order of 10 3 times greater than nuclear weapons testing fallout levels.« less

237 Np analytical method using 239 Np tracers and application to a contaminated nuclear disposal facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snow, Mathew S.; Morrison, Samuel S.; Clark, Sue B.

2017-06-01

Environmental 237Np analyses are challenged by low 237Np concentrations and lack of an available yield tracer; we report a rapid, inexpensive 237Np analytical approach employing the short lived 239Np (t1/2 = 2.3 days) as a chemical yield tracer followed by 237Np quantification using inductively coupled plasma-mass spectrometry. 239Np tracer is obtained via separation from a 243Am stock solution and standardized using gamma spectrometry immediately prior to sample processing. Rapid digestions using a commercial, 900 watt “Walmart” microwave and Parr microwave vessels result in 99.8 ± 0.1% digestion yields, while chromatographic separations enable Np/U separation factors on the order of 106more » and total Np yields of 95 ± 4% (2σ). Application of this method to legacy soil samples surrounding a radioactive disposal facility (the Subsurface Disposal Area at Idaho National Laboratory) reveal the presence of low level 237Np contamination within 600 meters of this site, with maximum 237Np concentrations on the order of 103 times greater than nuclear weapons testing fallout levels.« less

237Np analytical method using 239Np tracers and application to a contaminated nuclear disposal facility.

PubMed

Snow, Mathew S; Morrison, Samuel S; Clark, Sue B; Olson, John E; Watrous, Matthew G

2017-06-01

Environmental 237 Np analyses are challenged by low 237 Np concentrations and lack of an available yield tracer; we report a rapid, inexpensive 237 Np analytical approach employing the short lived 239 Np (t 1/2  = 2.3 days) as a chemical yield tracer followed by 237 Np quantification using inductively coupled plasma-mass spectrometry. 239 Np tracer is obtained via separation from a 243 Am stock solution and standardized using gamma spectrometry immediately prior to sample processing. Rapid digestions using a commercial, 900 W "Walmart" microwave and Parr microwave vessels result in 99.8 ± 0.1% digestion yields, while chromatographic separations enable Np/U separation factors on the order of 10 6 and total Np yields of 95 ± 4% (2σ). Application of this method to legacy soil samples surrounding a radioactive disposal facility (the Subsurface Disposal Area at Idaho National Laboratory) reveal the presence of low level 237 Np contamination within 600 m of this site, with maximum 237 Np concentrations on the order of 10 3 times greater than nuclear weapons testing fallout levels. Copyright © 2017 Elsevier Ltd. All rights reserved.

Human papillomavirus vaccination coverage using two-dose or three-dose schedule criteria.

PubMed

Lin, Xia; Rodgers, Loren; Zhu, Liping; Stokley, Shannon; Meites, Elissa; Markowitz, Lauri E

2017-10-13

In October 2016, the Advisory Committee on Immunization Practices (ACIP) updated the human papillomavirus (HPV) vaccination recommendation to include a 2-dose schedule for U.S. adolescents initiating the vaccine series before their 15th birthday. We analyzed records for >4million persons aged 9-17years receiving any HPV vaccine by the end of each quarter during January 1, 2014-September 30, 2016 from six Immunization Information Systems Sentinel Sites, and reclassified HPV vaccination up-to-date coverage according to the updated recommendations. Compared with HPV vaccination up-to-date coverage by the 3-dose schedule only, including criteria for either a 2-dose or 3-dose schedule increased up-to-date coverage in 11-12, 13-14, and 15-17 year-olds by 4.5-8.5 percentage points. The difference between 3-dose up-to-date coverage and 2- or 3-dose up-to-date coverage was greatest in late 2016. These data provide baseline HPV vaccination coverage using current ACIP recommendations. Published by Elsevier Ltd.

42 CFR 456.237 - Notification of adverse decision.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Notification of adverse decision. 456.237 Section 456.237 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental Hospitals...

48 CFR 252.237-7011 - Preparation history.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Preparation history. 252.237-7011 Section 252.237-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

48 CFR 252.237-7011 - Preparation history.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Preparation history. 252.237-7011 Section 252.237-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

48 CFR 252.237-7011 - Preparation history.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Preparation history. 252.237-7011 Section 252.237-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

48 CFR 252.237-7011 - Preparation history.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Preparation history. 252.237-7011 Section 252.237-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

48 CFR 252.237-7011 - Preparation history.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Preparation history. 252.237-7011 Section 252.237-7011 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

48 CFR 352.237-71 - Crime Control Act-reporting of child abuse.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-reporting of child abuse. 352.237-71 Section 352.237-71 Federal Acquisition Regulations System HEALTH AND... personnel and administrators, nurses, health care practitioners, chiropractors, osteopaths, pharmacists... personnel, psychologists, psychiatrists, mental health professionals, child care workers and administrators...

48 CFR 352.237-71 - Crime Control Act-reporting of child abuse.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-reporting of child abuse. 352.237-71 Section 352.237-71 Federal Acquisition Regulations System HEALTH AND... personnel and administrators, nurses, health care practitioners, chiropractors, osteopaths, pharmacists... personnel, psychologists, psychiatrists, mental health professionals, child care workers and administrators...

48 CFR 352.237-71 - Crime Control Act-reporting of child abuse.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-reporting of child abuse. 352.237-71 Section 352.237-71 Federal Acquisition Regulations System HEALTH AND... personnel and administrators, nurses, health care practitioners, chiropractors, osteopaths, pharmacists... personnel, psychologists, psychiatrists, mental health professionals, child care workers and administrators...

48 CFR 352.237-71 - Crime Control Act-reporting of child abuse.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-reporting of child abuse. 352.237-71 Section 352.237-71 Federal Acquisition Regulations System HEALTH AND... personnel and administrators, nurses, health care practitioners, chiropractors, osteopaths, pharmacists... personnel, psychologists, psychiatrists, mental health professionals, child care workers and administrators...

49 CFR 237.51 - Railroad bridge engineers.

Code of Federal Regulations, 2013 CFR

2013-10-01

... engineering work to be performed: (1) Determine the forces and stresses in railroad bridges and bridge... 49 Transportation 4 2013-10-01 2013-10-01 false Railroad bridge engineers. 237.51 Section 237.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...

49 CFR 237.51 - Railroad bridge engineers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... engineering work to be performed: (1) Determine the forces and stresses in railroad bridges and bridge... 49 Transportation 4 2012-10-01 2012-10-01 false Railroad bridge engineers. 237.51 Section 237.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...

49 CFR 237.51 - Railroad bridge engineers.

Code of Federal Regulations, 2014 CFR

2014-10-01

... engineering work to be performed: (1) Determine the forces and stresses in railroad bridges and bridge... 49 Transportation 4 2014-10-01 2014-10-01 false Railroad bridge engineers. 237.51 Section 237.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...

49 CFR 237.51 - Railroad bridge engineers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... engineering work to be performed: (1) Determine the forces and stresses in railroad bridges and bridge... 49 Transportation 4 2010-10-01 2010-10-01 false Railroad bridge engineers. 237.51 Section 237.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...

49 CFR 237.51 - Railroad bridge engineers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... engineering work to be performed: (1) Determine the forces and stresses in railroad bridges and bridge... 49 Transportation 4 2011-10-01 2011-10-01 false Railroad bridge engineers. 237.51 Section 237.51 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...

48 CFR 237.7202 - Limitations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Limitations. 237.7202 Section 237.7202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... funds for tuition or other expenses for training in any legal profession, except in connection with the...

48 CFR 237.7001 - Method of acquisition.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Method of acquisition. 237.7001 Section 237.7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... contract exists, use DD Form 1155, Order for Supplies or Services, to obtain mortuary services. ...

48 CFR 237.7204 - Format and clauses for educational service agreements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... educational service agreements. 237.7204 Section 237.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING... practices and procedures for other students of similar accomplishment in that department or field. The...

48 CFR 237.7204 - Format and clauses for educational service agreements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... educational service agreements. 237.7204 Section 237.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING... practices and procedures for other students of similar accomplishment in that department or field. The...

48 CFR 237.7204 - Format and clauses for educational service agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... educational service agreements. 237.7204 Section 237.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING... practices and procedures for other students of similar accomplishment in that department or field. The...

48 CFR 237.7204 - Format and clauses for educational service agreements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... educational service agreements. 237.7204 Section 237.7204 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING... practices and procedures for other students of similar accomplishment in that department or field. The...

48 CFR 237.7301 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... granting educational institution that— (1) Is located in the United States or its outlying areas; (2) Has... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Definitions. 237.7301 Section 237.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

TTI-237: a novel microtubule-active compound with in vivo antitumor activity.

PubMed

Beyer, Carl F; Zhang, Nan; Hernandez, Richard; Vitale, Danielle; Lucas, Judy; Nguyen, Thai; Discafani, Carolyn; Ayral-Kaloustian, Semiramis; Gibbons, James J

2008-04-01

5-Chloro-6-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine butanedioate (TTI-237) is a microtubule-active compound of novel structure and function. Structurally, it is one of a class of compounds, triazolo[1,5a]pyrimidines, previously not known to bind to tubulin. Functionally, TTI-237 inhibited the binding of [(3)H]vinblastine to tubulin, but it caused a marked increase in turbidity development that more closely resembled the effect observed with docetaxel than that observed with vincristine. The morphologic character of the presumptive polymer is unknown at present. When applied to cultured human tumor cells at concentrations near its IC(50) value for cytotoxicity (34 nmol/L), TTI-237 induced multiple spindle poles and multinuclear cells, as did paclitaxel, but not vincristine or colchicine. Flow cytometry experiments revealed that, at low concentrations (20-40 nmol/L), TTI-237 produced sub-G(1) nuclei and, at concentrations above 50 nmol/L, it caused a strong G(2)-M block. The compound was a weak substrate of multidrug resistance 1 (multidrug resistance transporter or P-glycoprotein). In a cell line expressing a high level of P-glycoprotein, the IC(50) of TTI-237 increased 25-fold whereas those of paclitaxel and vincristine increased 806-fold and 925-fold, respectively. TTI-237 was not recognized by the MRP or MXR transporters. TTI-237 was active in vivo in several nude mouse xenograft models of human cancer, including LoVo human colon carcinoma and U87-MG human glioblastoma, when dosed i.v. or p.o. Thus, TTI-237 has a set of properties that distinguish it from other classes of microtubule-active compounds.

Lab Aliens, Legendary Fossils, and Deadly Science Potions: Views of Science and Scientists from Fifth Graders in a Free-Choice Creative Writing Program

NASA Astrophysics Data System (ADS)

Hellman, Leslie G.

This qualitative study uses children's writing to explore the divide between a conception of Science as a humanistic discipline reliant on creativity, ingenuity and out of the box thinking and a persistent public perception of science and scientists as rigid and methodical. Artifacts reviewed were 506 scripts written during 2014 and 2016 by 5th graders participating in an out-of classroom, mentor supported, free-choice 10-week arts and literacy initiative. 47% (237) of these scripts were found to contain content relating to Science, Scientists, Science Education and the Nature of Science. These 237 scripts were coded for themes; characteristics of named scientist characters were tracked and analyzed. Findings included NOS understandings being expressed by representation of Science and Engineering Practices; Ingenuity being primarily linked to Engineering tasks; common portrayals of science as magical or scientists as villains; and a persistence in negative stereotypes of scientists, including a lack of gender equity amongst the named scientist characters. Findings suggest that representations of scientists in popular culture highly influence the portrayals of scientists constructed by the students. Recommendations to teachers include encouraging explicit consideration of big-picture NOS concepts such as ethics during elementary school and encouraging the replacement of documentary or educational shows with more engaging fictional media.

Exome sequencing identifies a novel mutation of the GDI1 gene in a Chinese non-syndromic X-linked intellectual disability family

PubMed Central

Duan, Yongheng; Lin, Sheng; Xie, Lichun; Zheng, Kaifeng; Chen, Shiguo; Song, Hui; Zeng, Xuchun; Gu, Xueying; Wang, Heyun; Zhang, Linghua; Shao, Hao; Hong, Wenxu; Zhang, Lijie; Duan, Shan

2017-01-01

Abstract X-linked intellectual disability (XLID) has been associated with various genes. Diagnosis of XLID, especially for non-syndromic ones (NS-XLID), is often hampered by the heterogeneity of this disease. Here we report the case of a Chinese family in which three males suffer from intellectual disability (ID). The three patients shared the same phenotype: no typical clinical manifestation other than IQ score ≤ 70. For a genetic diagnosis for this family we carried out whole exome sequencing on the proband, and validated 16 variants of interest in the genomic DNA of all the family members. A missense mutation (c.710G > T), which mapped to exon 6 of the Rab GDP-Dissociation Inhibitor 1 (GDI1) gene, was found segregating with the ID phenotype, and this mutation changes the 237th position in the guanosine diphosphate dissociation inhibitor (GDI) protein from glycine to valine (p. Gly237Val). Through molecular dynamics simulations we found that this substitution results in a conformational change of GDI, possibly affecting the Rab-binding capacity of this protein. In conclusion, our study identified a novel GDI1 mutation that is possibly NS-XLID causative, and showed that whole exome sequencing provides advantages for detecting novel ID-associated variants and can greatly facilitate the genetic diagnosis of the disease. PMID:28863211

36 CFR 2.37 - Noncommercial soliciting.

Code of Federal Regulations, 2010 CFR

2010-07-01

....37 Section 2.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR RESOURCE PROTECTION, PUBLIC USE AND RECREATION § 2.37 Noncommercial soliciting. Soliciting or demanding gifts, money, goods or services is prohibited, except pursuant to the terms and conditions of a permit...

Rabies neutralizing antibody response to different schedules of serum and vaccine inoculations in non-exposed persons

PubMed Central

Atanasiu, P.; Bahmanyar, M.; Baltazard, M.; Fox, J. P.; Habel, K.; Kaplan, M. M.; Kissling, R. E.; Komarov, A.; Koprowski, H.; Lépine, P.; Gallardo, F. Pérez; Schaeffer, M.

1957-01-01

Further studies were made on groups of adult humans, previously unexposed to rabies and with no history of rabies vaccination, who were inoculated with different schedules of phenolized inactivated vaccine given subcutaneously and high egg passage (HEP) Flury strain vaccine given intradermally, with and without inoculation of antirabies serum. Serum specimens of the inoculated individuals were studied for antibody up to the 60th day after the first inoculation of the vaccines and serum. Studies were also made on the effect of “booster” doses of HEP Flury strain vaccine given 6 months after preparatory inoculations. The results can be summarized as follows: 1. Fourteen daily inoculations of phenolized vaccine produced a superior antibody response to that obtained with 3 inoculations given 5 days apart. 2. Three intradermal inoculations of HEP Flury vaccine given 5 days apart gave a low level of antibody response, but these individuals responded efficiently by producing antibody to a “booster” dose of the same vaccine given 6 months later. 3. Administration of phenolized vaccine or of HEP Flury vaccine alone did not produce detectable antibody in most individuals until between the 10th and the 15th day after the first inoculation of the vaccine. 4. Passive antibody following inoculation of antirabies serum persisted in some individuals for as long as 42 days. Two inoculations of serum administered 5 days apart did not give levels of antibody higher than those obtained with one inoculation. 5. One inoculation of serum completely suppressed antibody response to 3 inoculations of Flury vaccine given intradermally 5 days apart, and also prevented the preparation of the individuals to respond to a later “booster” dose of this vaccine. 6. Three inoculation of phenolized vaccine given 5 days apart acted efficiently in producing antibody by the 60th day. However, the interfering action of one and two inoculations of serum was clearly defined in this schedule. 7. One inoculation of serum had no suppressive effect on the active antibody response to 14 daily doses of phenolized vaccine; two doses of serum given in the same combination definitely interfered with the production of an active antibody response. PMID:13511138

Analysis of trace neptunium in the vicinity of underground nuclear tests at the Nevada National Security Site.

PubMed

Zhao, P; Tinnacher, R M; Zavarin, M; Kersting, A B

2014-11-01

A high sensitivity analytical method for (237)Np analysis was developed and applied to groundwater samples from the Nevada National Security Site (NNSS) using short-lived (239)Np as a yield tracer and HR magnetic sector ICP-MS. The (237)Np concentrations in the vicinity of the Almendro, Cambric, Dalhart, Cheshire, and Chancellor underground nuclear test locations range from <4 × 10(-4) to 2.6 mBq/L (6 × 10(-17)-4.2 × 10(-13) mol/L). All measured (237)Np concentrations are well below the drinking water maximum contaminant level for alpha emitters identified by the U.S. EPA (560 mBq/L). Nevertheless, (237)Np remains an important indicator for radionuclide transport rates at the NNSS. Retardation factor ratios were used to compare the mobility of (237)Np to that of other radionuclides. The results suggest that (237)Np is less mobile than tritium and other non-sorbing radionuclides ((14)C, (36)Cl, (99)Tc and (129)I) as expected. Surprisingly, (237)Np and plutonium ((239,240)Pu) retardation factors are very similar. It is possible that Np(IV) exists under mildly reducing groundwater conditions and exhibits a retardation behavior that is comparable to Pu(IV). Independent of the underlying process, (237)Np is migrating downgradient from NNSS underground nuclear tests at very low but measureable concentrations. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

A phase I dose escalation study of TTI-237 in patients with advanced malignant solid tumors.

PubMed

Wang-Gillam, Andrea; Arnold, Susanne M; Bukowski, Ronald M; Rothenberg, Mace L; Cooper, Wendy; Wang, Kenneth K; Gauthier, Eric; Lockhart, A Craig

2012-02-01

This study was to determine the maximum tolerated dose, dose-limiting toxicities, and pharmacokinetic profile of TTI-237, a novel anti-tubulin drug, administered weekly in patients with refractory solid tumors. Using an accelerated dose escalation design, patients with refractory solid tumors were enrolled in this study and treated with TTI-237 intravenously on days 1, 8 and 15 of a 28-day cycle. The starting dose was 4.5 mg/m(2). Pharmacokinetic studies were performed in patients at all dose levels. Twenty-eight patients were enrolled and treated with TTI-237 at dose of 4.5, 9, 15, 22.5 and 31.5 mg/m(2). One dose-limiting toxicity neutropenia fever was observed at 31.5 mg/m(2), and all seven patients developed grade 3 or 4 neutropenia at that dose level. TTI-237 dosage was de-escalated to 22.5 and 18 mg/m(2). Six patients were treated at the 18 mg/m(2) dose level without dose-limiting toxicity prior to trial termination. The mean terminal-phase elimination half-life (t(1/2)) for TTI-237 was 25-29 h, and the mean area under the concentration time curve at 31.5 mg/m(2) was 2,768 ng•h/mL. A protocol defined maximum tolerated dose was not determined because of early termination of the TTI-237 trial by the sponsor. 18 mg/m(2) may be a tolerable dose of TTI-237.

An Application of Course Scheduling in the Brazilian Air Force

DTIC Science & Technology

2012-03-01

LA - lnstituto de Logistic ada Forc;;a Aerea Brasileira- Av Monteiro Lobato 5335- Guarulhos - SP - Brazil •Tel (55 ) 11 -64652109 Email julio inb...February, 2005, from http://www.sc.ehu.es/ccwbayes/docencia/mmcc/docs/ lecturas -heuristicos- optimizacion/TimetablingbyGAs.pdf, accessed on 10th

Role of Receptor Sialylation in the Ovarian Tumor Cell Phenotype

DTIC Science & Technology

2014-08-01

Chemical Society meeting, Baton Rouge, LA, Nov 2012; (3) 19th World Congress on Advances in Oncology conference, Athens, Greece, scheduled for Oct, 2014...dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009;69

49 CFR 237.33 - Content of bridge management programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Content of bridge management programs. 237.33... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.33 Content of bridge management programs. Each bridge management program adopted in compliance with this part...

49 CFR 237.111 - Review of bridge inspection reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and railroad...

2. VIEW WEST, REAR AND FERNOW EXPERIMENTAL FOREST BUNKHOUSE ON ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. VIEW WEST, REAR AND FERNOW EXPERIMENTAL FOREST BUNKHOUSE ON RIGHT. (see also WV-237-6, WV-237-N-2, and historic photograph WV-237-N-5) - Parsons Nursery, Fernow Experimental Forest Well House, South side of U.S. Route 219, Parsons, Tucker County, WV

9 CFR 2.37 - Federal research facilities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

9 CFR 2.37 - Federal research facilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

9 CFR 2.37 - Federal research facilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

48 CFR 2152.237-70 - Continuity of services.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... 2152.237-70 Section 2152.237-70 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT... Government or another Contractor, may continue them. The Contractor agrees to furnish phase-in training and...) The Contractor shall, upon the Contracting Officer's written notice, (1) furnish phase-in and phase...

49 CFR 199.237 - Other alcohol-related conduct.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Other alcohol-related conduct. 199.237 Section 199... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Alcohol Misuse Prevention Program § 199.237 Other alcohol-related conduct. (a) No operator shall...

49 CFR 199.237 - Other alcohol-related conduct.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Other alcohol-related conduct. 199.237 Section 199... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY DRUG AND ALCOHOL TESTING Alcohol Misuse Prevention Program § 199.237 Other alcohol-related conduct. (a) No operator shall...

48 CFR 237.7002 - Area of performance and distribution of contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Area of performance and distribution of contracts. 237.7002 Section 237.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Mortuary...

9 CFR 2.37 - Federal research facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Federal research facilities. 2.37... AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.37 Federal research facilities. Each Federal research facility shall establish an Institutional Animal Care and Use Committee which shall have the same...

48 CFR 3452.237-71 - Services of consultants.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Services of consultants. 3452.237-71 Section 3452.237-71 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION... set forth, $150, exclusive of travel costs, or if the services of any consultant under this contract...

49 CFR 237.111 - Review of bridge inspection reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Review of bridge inspection reports. 237.111... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Bridge Inspection § 237.111 Review of bridge inspection reports. Bridge inspection reports shall be reviewed by railroad bridge supervisors and railroad...

49 CFR 237.33 - Content of bridge management programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Content of bridge management programs. 237.33... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.33 Content of bridge management programs. Each bridge management program adopted in compliance with this part...

Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.

PubMed

Rai, Devendra K; Diaz-San Segundo, Fayna; Campagnola, Grace; Keith, Anna; Schafer, Elizabeth A; Kloc, Anna; de Los Santos, Teresa; Peersen, Olve; Rieder, Elizabeth

2017-08-01

Foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp) (3D pol ) catalyzes viral RNA synthesis. Its characteristic low fidelity and absence of proofreading activity allow FMDV to rapidly mutate and adapt to dynamic environments. In this study, we used the structure of FMDV 3D pol in combination with previously reported results from similar picornaviral polymerases to design point mutations that would alter replication fidelity. In particular, we targeted Trp237 within conserved polymerase motif A because of the low reversion potential inherent in the single UGG codon. Using biochemical and genetic tools, we show that the replacement of tryptophan 237 with phenylalanine imparts higher fidelity, but replacements with isoleucine and leucine resulted in lower-fidelity phenotypes. Viruses containing these W237 substitutions show in vitro growth kinetics and plaque morphologies similar to those of the wild-type (WT) A 24 Cruzeiro strain in BHK cells, and both high- and low-fidelity variants retained fitness during coinfection with the wild-type virus. The higher-fidelity W237F (W237F HF ) mutant virus was more resistant to the mutagenic nucleoside analogs ribavirin and 5-fluorouracil than the WT virus, whereas the lower-fidelity W237I (W237I LF ) and W237L LF mutant viruses exhibited lower ribavirin resistance. Interestingly, the variant viruses showed heterogeneous and slightly delayed growth kinetics in primary porcine kidney cells, and they were significantly attenuated in mouse infection experiments. These data demonstrate, for a single virus, that either increased or decreased RdRp fidelity attenuates virus growth in animals, which is a desirable feature for the development of safer and genetically more stable vaccine candidates. IMPORTANCE Foot-and-mouth disease (FMD) is the most devastating disease affecting livestock worldwide. Here, using structural and biochemical analyses, we have identified FMDV 3D pol mutations that affect polymerase fidelity. Recombinant FMDVs containing substitutions at 3D pol tryptophan residue 237 were genetically stable and displayed plaque phenotypes and growth kinetics similar to those of the wild-type virus in cell culture. We further demonstrate that viruses harboring either a W237F HF substitution or W237I LF and W237L LF mutations were highly attenuated in animals. Our study shows that obtaining 3D pol fidelity variants by protein engineering based on polymerase structure and function could be exploited for the development of attenuated FMDV vaccine candidates that are safer and more stable than strains obtained by selective pressure via mutagenic nucleotides or adaptation approaches. Copyright © 2017 American Society for Microbiology.

Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity

PubMed Central

Rai, Devendra K.; Diaz-San Segundo, Fayna; Campagnola, Grace; Keith, Anna; Schafer, Elizabeth A.; Kloc, Anna; de los Santos, Teresa; Peersen, Olve

2017-01-01

ABSTRACT Foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp) (3Dpol) catalyzes viral RNA synthesis. Its characteristic low fidelity and absence of proofreading activity allow FMDV to rapidly mutate and adapt to dynamic environments. In this study, we used the structure of FMDV 3Dpol in combination with previously reported results from similar picornaviral polymerases to design point mutations that would alter replication fidelity. In particular, we targeted Trp237 within conserved polymerase motif A because of the low reversion potential inherent in the single UGG codon. Using biochemical and genetic tools, we show that the replacement of tryptophan 237 with phenylalanine imparts higher fidelity, but replacements with isoleucine and leucine resulted in lower-fidelity phenotypes. Viruses containing these W237 substitutions show in vitro growth kinetics and plaque morphologies similar to those of the wild-type (WT) A24 Cruzeiro strain in BHK cells, and both high- and low-fidelity variants retained fitness during coinfection with the wild-type virus. The higher-fidelity W237F (W237FHF) mutant virus was more resistant to the mutagenic nucleoside analogs ribavirin and 5-fluorouracil than the WT virus, whereas the lower-fidelity W237I (W237ILF) and W237LLF mutant viruses exhibited lower ribavirin resistance. Interestingly, the variant viruses showed heterogeneous and slightly delayed growth kinetics in primary porcine kidney cells, and they were significantly attenuated in mouse infection experiments. These data demonstrate, for a single virus, that either increased or decreased RdRp fidelity attenuates virus growth in animals, which is a desirable feature for the development of safer and genetically more stable vaccine candidates. IMPORTANCE Foot-and-mouth disease (FMD) is the most devastating disease affecting livestock worldwide. Here, using structural and biochemical analyses, we have identified FMDV 3Dpol mutations that affect polymerase fidelity. Recombinant FMDVs containing substitutions at 3Dpol tryptophan residue 237 were genetically stable and displayed plaque phenotypes and growth kinetics similar to those of the wild-type virus in cell culture. We further demonstrate that viruses harboring either a W237FHF substitution or W237ILF and W237LLF mutations were highly attenuated in animals. Our study shows that obtaining 3Dpol fidelity variants by protein engineering based on polymerase structure and function could be exploited for the development of attenuated FMDV vaccine candidates that are safer and more stable than strains obtained by selective pressure via mutagenic nucleotides or adaptation approaches. PMID:28515297

CAPABILITY TO RECOVER PLUTONIUM-238 IN H-CANYON/HB-LINE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fuller, Kenneth S. Jr.; Smith, Robert H. Jr.; Goergen, Charles R.

2013-01-09

Plutonium-238 is used in Radioisotope Thermoelectric Generators (RTGs) to generate electrical power and in Radioisotope Heater Units (RHUs) to produce heat for electronics and environmental control for deep space missions. The domestic supply of Pu-238 consists of scrap material from previous mission production or material purchased from Russia. Currently, the United States has no significant production scale operational capability to produce and separate new Pu-238 from irradiated neptunium-237 targets. The Department of Energy - Nuclear Energy is currently evaluating and developing plans to reconstitute the United States capability to produce Pu-238 from irradiated Np-237 targets. The Savannah River Site hadmore » previously produced and/or processed all the Pu-238 utilized in Radioisotope Thermoelectric Generators (RTGs) for deep space missions up to and including the majority of the plutonium for the Cassini Mission. The previous full production cycle capabilities included: Np-237 target fabrication, target irradiation, target dissolution and Np-237 and Pu-238 separation and purification, conversion of Np-237 and Pu-238 to oxide, scrap recovery, and Pu-238 encapsulation. The capability and equipment still exist and could be revitalized or put back into service to recover and purify Pu-238/Np-237 or broken General Purpose Heat Source (GPHS) pellets utilizing existing process equipment in HB-Line Scrap Recovery, and H-anyon Frame Waste Recovery processes. The conversion of Np-237 and Pu-238 to oxide can be performed in the existing HB-Line Phase-2 and Phase-3 Processes. Dissolution of irradiated Np-237 target material, and separation and purification of Np-237 and Pu-238 product streams would be possible at production rates of ~ 2 kg/month of Pu-238 if the existing H-Canyon Frames Process spare equipment were re-installed. Previously, the primary H-Canyon Frames equipment was removed to be replaced: however, the replacement project was stopped. The spare equipment is stored and still available for installation. Out of specification Pu-238 scrap material can be purified and recovered by utilizing the HB-Line Phase-1 Scrap Recovery Line and the Phase-3 Pu-238 Oxide Conversion Line along with H-Canyon Frame Waste Recovery process. In addition, it also covers and describes utilizing the Phase-2 Np-237 Oxide Conversion Line, in conjunction with the H-Canyon Frames Process to restore the H-Canyon capability to process and recover Np-237 and Pu-238 from irradiated Np-237 targets and address potential synergies with other programs like recovery of Pu-244 and heavy isotopes of curium from other target material.« less

49 CFR 237.71 - Determination of bridge load capacities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Determination of bridge load capacities. 237.71... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Capacity of Bridges § 237.71 Determination of bridge load capacities. (a) Each track owner shall determine the load capacity of each of its...

49 CFR 237.31 - Adoption of bridge management programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Adoption of bridge management programs. 237.31... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.31 Adoption of bridge management programs. Each track owner shall adopt a bridge safety management program to...

30 CFR 23.7 - Specific requirements for approval.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Specific requirements for approval. 23.7...

30 CFR 23.7 - Specific requirements for approval.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Specific requirements for approval. 23.7...

30 CFR 23.7 - Specific requirements for approval.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., EVALUATION, AND APPROVAL OF MINING PRODUCTS TELEPHONES AND SIGNALING DEVICES § 23.7 Specific requirements for... apply. (g) Line powered telephones and signaling devices or systems shall be equipped with standby power... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Specific requirements for approval. 23.7...

14 CFR 16.237 - Waiver of procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Waiver of procedures. 16.237 Section 16.237 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES RULES OF... of this issue on appeal. (c) The parties may not by consent waive the obligation of the hearing...

14 CFR 16.237 - Waiver of procedures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Waiver of procedures. 16.237 Section 16.237 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES RULES OF... of this issue on appeal. (c) The parties may not by consent waive the obligation of the hearing...

14 CFR 16.237 - Waiver of procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Waiver of procedures. 16.237 Section 16.237 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES RULES OF... of this issue on appeal. (c) The parties may not by consent waive the obligation of the hearing...

14 CFR 16.237 - Waiver of procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Waiver of procedures. 16.237 Section 16.237 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES RULES OF... of this issue on appeal. (c) The parties may not by consent waive the obligation of the hearing...

14 CFR 16.237 - Waiver of procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Waiver of procedures. 16.237 Section 16.237 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL RULES RULES OF... of this issue on appeal. (c) The parties may not by consent waive the obligation of the hearing...

30 CFR 285.237 - What is the effective date of a lease?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 285.237 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Commercial and Limited Lease Terms § 285.237 What is...

40 CFR 415.237 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2010 CFR

2010-07-01

... control technology (BCT). 415.237 Section 415.237 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE... control technology (BCT). Except as provided in 40 CFR 125.30 through 125.32, any existing point source...

12 CFR 237.20 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the Board's Regulation K (12 CFR 211.21(n)). Major security-based swap participant has the same... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Definitions. 237.20 Section 237.20 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED...

32 CFR 237a.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Purpose. 237a.1 Section 237a.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PUBLIC AFFAIRS... with industry on (1) public affairs matters in general, (2) industry-sponsored events, and (3...

48 CFR 1452.237-71 - Utilization of Woody Biomass.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Biomass. 1452.237-71 Section 1452.237-71 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Utilization of Woody Biomass. As prescribed in § 1437.7202, insert the following clause: Utilization of Woody Biomass (MAY 2005) (a) The contractor may remove and utilize woody biomass, if: (1) Project work is...

48 CFR 1552.237-70 - Contract publication review procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract publication review procedures. 1552.237-70 Section 1552.237-70 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION... Project Officer, at least 30 days prior to publication, a copy of any paper, article, or other...

49 CFR 237.71 - Determination of bridge load capacities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Determination of bridge load capacities. 237.71... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Capacity of Bridges § 237.71 Determination of bridge load capacities. (a) Each track owner shall determine the load capacity of each of its...

49 CFR 237.31 - Adoption of bridge management programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Adoption of bridge management programs. 237.31... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION BRIDGE SAFETY STANDARDS Railroad Bridge Safety Assurance § 237.31 Adoption of bridge management programs. Each track owner shall adopt a bridge safety management program to...

42 CFR 456.237 - Notification of adverse decision.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false Notification of adverse decision. 456.237 Section 456.237 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... § 456.236 (f) through (h) is sent to— (a) The hospital administrator; (b) The attending or staff...

17 CFR 256.237 - Interest accrued.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

17 CFR 256.237 - Interest accrued.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

{sup 237}Np in Hemp-palm leaves of Bontenchiku for fishing gear used by the Fifth Fukuryu-Maru: 40 year after {open_quotes}Bravo{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamamoto, Masayoshi; Komura, Kazuhisa; Ueno, Kaoru

1996-05-01

The alpha radioactive components in the Hemp-palm leaves of Bontenchiku were determined with emphasis on the measurement of low-level {sup 237}Np by alpha-ray spectrometry after chemical separation. Bontenchiku is a kind of fishing gear for long-line fishing used by the Fifth Fukuryu-Maru (Lucky Dragon). This gear was exposed to fallout from the second thermonuclear test explosion (Bravo) at Bikini Atoll in March 1954. The {sup 237}Np content in the Bontenchiku sample was determined to be 11.5 {plus_minus}0.8 mBq g{sup {minus}1} with an activity ratio of {sup 237}Np: {sup 239,240}Pu and an atom ratio of {sup 237}Np: {sup 239}Pu estimated tomore » be (2.2 {plus_minus}0.2) x 10{sup {minus}3} and 0.42 {plus_minus}0.04, respectively. The data showed the existence of a chain reaction of {sup 238}U and its ratio to be {sup 237}Np: {sup 239}Pu, as well as the presence of {sup 237}U at the time of fallout from Bravo event in March 1954. 12 refs., 5 figs., 1 tab.« less

Women's autonomy and scheduled cesarean sections in Brazil: a cautionary tale.

PubMed

Potter, Joseph E; Hopkins, Kristine; Faúndes, Anibal; Perpétuo, Ignez

2008-03-01

In Brazil, one-fourth of all women deliver in the private sector, where the rate of cesarean deliveries is extremely high (70%). Most (64%) private sector cesareans are scheduled, although many women would have preferred a vaginal delivery. The question this study addresses is whether childbearing women were induced to accept the procedure by their physicians, and if so, how? Three face-to-face structured interviews were conducted with 1,612 women (519 private sector and 1,093 public sector) early in pregnancy, approximately 1 month before their due date, and approximately 1 month postpartum. For all private sector patients having a scheduled cesarean section, women's self-reported reasons given for programming surgical delivery were classified into three groups according to obstetrical justification. After loss to follow-up (19.2% of private sector and 34.4% of public sector), our final sample included 1,136 women (419 private sector and 717 public sector). Compared with public sector participants in the final sample, on average, private sector participants were older by 3.4 years (28.7 vs 25.3 yr), had 0.4 fewer previous deliveries (0.6 vs 1.0), and had 3.4 more years of education (11.0 vs 7.6 yr). The final samples also differed slightly with respect to preference for vaginal delivery: 72.3 percent among those in the private sector and 79.6 percent in public sector. The cesarean section rate was 72 percent in the private sector and 31 percent in the public sector. Of the women with reports about the timing of the cesarean decision, 64.4 percent had a scheduled cesarean delivery in the private sector compared with 23.7 percent in the public sector. Many cesarean sections were scheduled for an "unjustified" medical reason, especially among women who, during pregnancy, had declared a preference for a vaginal delivery. Among 96 women in this latter group, the reason reported for the procedure was unjustified in 33 cases. On the other hand, more cesarean deliveries were scheduled for "no medical justification," including physician's or the woman's convenience, among women who preferred to deliver by cesarean (35/65). The incidence of real medical reasons for a scheduled cesarean section diagnosed before the onset of labor among private sector patients who had no previous cesarean birth and who wanted a vaginal delivery was 13 percent (31/243). The data suggest that doctors frequently persuaded their patients to accept a scheduled cesarean section for conditions that either did not exist or did not justify this procedure. The problem identified in this paper may extend well beyond Brazil and should be of concern to those with responsibility for ethical behavior in obstetrics.

[Studies on the physical dependence liability of chlorphenesin carbamate (author's transl)].

PubMed

Sasajima, M; Tarumoto, Y; Aihara, H; Tanaka, Y; Saito, S

1977-05-01

Physical dependence liability of chlorphenesin carbamate (CPC) was studied in parallel with phenobarbital-Na (PB). Beagle dogs were used and the overall duration of the experiment was 85 days, i.e. the first dosing period was 42 dyas (6 weeks) in which drugs were repeatedly administered orally once daily, followed by a withdrawal period (7 days), the second dosing period was continued from the 50th-78th day in which the form and schedule of drug administration was as in the first dosing period. The last 79th to 85th days were used for substitution experiments. In both dosing periods, PB but not CPC showed signs of tolerance formation. Severe withdrawal syndrome was observed in PB administered dogs whereas there were no changes of behavior observed in CPC-dogs by withdrawal and substitution procedures, respectively. CPC apparently does not have a physical dependence liability.

30 CFR 585.237 - What is the effective date of a lease?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Section 585.237 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Commercial and Limited Lease Terms § 585.237 What is the effective date of a lease...

30 CFR 585.237 - What is the effective date of a lease?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Section 585.237 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Commercial and Limited Lease Terms § 585.237 What is the effective date of a lease...

30 CFR 585.237 - What is the effective date of a lease?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 585.237 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Commercial and Limited Lease Terms § 585.237 What is the effective date of a lease...

49 CFR 234.237 - Reverse switch cut-out circuit.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Reverse switch cut-out circuit. 234.237 Section... Maintenance, Inspection, and Testing Maintenance Standards § 234.237 Reverse switch cut-out circuit. A switch... system circuitry, shall be maintained so that the warning system can only be cut out when the switch...

5 CFR 838.237 - Death of the former spouse.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Death of the former spouse. 838.237... Affecting Employee Annuities Payment Procedures § 838.237 Death of the former spouse. (a) Unless the court... annuity terminates on the last day of the month before the death of the former spouse, and the former...

15 CFR 23.7 - Notice to Department of Commerce organizational units of implementation and procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... organizational units of implementation and procedures. 23.7 Section 23.7 Commerce and Foreign Trade Office of the... Department of Commerce organizational units of implementation and procedures. Following are roles and...) Otherwise determine and control the use of missing children materials and information by the Operating Unit...

49 CFR 234.237 - Reverse switch cut-out circuit.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Reverse switch cut-out circuit. 234.237 Section....237 Reverse switch cut-out circuit. A switch, when equipped with a switch circuit controller connected... warning system can only be cut out when the switch point is within one-half inch of full reverse position. ...

49 CFR 234.237 - Reverse switch cut-out circuit.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Reverse switch cut-out circuit. 234.237 Section....237 Reverse switch cut-out circuit. A switch, when equipped with a switch circuit controller connected... warning system can only be cut out when the switch point is within one-half inch of full reverse position. ...

49 CFR 234.237 - Reverse switch cut-out circuit.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Reverse switch cut-out circuit. 234.237 Section....237 Reverse switch cut-out circuit. A switch, when equipped with a switch circuit controller connected... warning system can only be cut out when the switch point is within one-half inch of full reverse position. ...

49 CFR 234.237 - Reverse switch cut-out circuit.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Reverse switch cut-out circuit. 234.237 Section... Maintenance, Inspection, and Testing Maintenance Standards § 234.237 Reverse switch cut-out circuit. A switch... system circuitry, shall be maintained so that the warning system can only be cut out when the switch...

49 CFR 237.133 - Supervision of repairs and modifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Supervision of repairs and modifications. 237.133... Supervision of repairs and modifications. Each repair or modification pursuant to this part shall be performed under the immediate supervision of a railroad bridge supervisor as defined in § 237.55 of this part who...

49 CFR 237.133 - Supervision of repairs and modifications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Supervision of repairs and modifications. 237.133... Supervision of repairs and modifications. Each repair or modification pursuant to this part shall be performed under the immediate supervision of a railroad bridge supervisor as defined in § 237.55 of this part who...

49 CFR 237.133 - Supervision of repairs and modifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Supervision of repairs and modifications. 237.133... Supervision of repairs and modifications. Each repair or modification pursuant to this part shall be performed under the immediate supervision of a railroad bridge supervisor as defined in § 237.55 of this part who...

49 CFR 237.133 - Supervision of repairs and modifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Supervision of repairs and modifications. 237.133... Supervision of repairs and modifications. Each repair or modification pursuant to this part shall be performed under the immediate supervision of a railroad bridge supervisor as defined in § 237.55 of this part who...

49 CFR 237.133 - Supervision of repairs and modifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Supervision of repairs and modifications. 237.133... Supervision of repairs and modifications. Each repair or modification pursuant to this part shall be performed under the immediate supervision of a railroad bridge supervisor as defined in § 237.55 of this part who...

6. Photo copy of photograph, (original in Forest Service Office, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #445511, 'Nursery Manager's Residence'), H. C. Frayer, July 1947. VIEW EAST. (see also historic photographs WV-237-12, WV-237-13, WV-237-26) - Parsons Nursery, Manager's Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

48 CFR 237.102-71 - Limitation on service contracts for military flight simulators.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts for military flight simulators. 237.102-71 Section 237.102-71 Federal Acquisition Regulations... flight simulators. (a) Definitions. As used in this subsection— (1) Military flight simulator means any... Law 110-181, DoD is prohibited from entering into a service contract to acquire a military flight...

48 CFR 237.102-71 - Limitation on service contracts for military flight simulators.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracts for military flight simulators. 237.102-71 Section 237.102-71 Federal Acquisition Regulations... flight simulators. (a) Definitions. As used in this subsection— (1) Military flight simulator means any... 110-181, DoD is prohibited from entering into a service contract to acquire a military flight...

48 CFR 237.102-71 - Limitation on service contracts for military flight simulators.

Code of Federal Regulations, 2012 CFR

2012-10-01

... contracts for military flight simulators. 237.102-71 Section 237.102-71 Federal Acquisition Regulations... flight simulators. (a) Definitions. As used in this subsection— (1) Military flight simulator means any... 110-181, DoD is prohibited from entering into a service contract to acquire a military flight...

48 CFR 237.102-71 - Limitation on service contracts for military flight simulators.

Code of Federal Regulations, 2013 CFR

2013-10-01

... contracts for military flight simulators. 237.102-71 Section 237.102-71 Federal Acquisition Regulations... flight simulators. (a) Definitions. As used in this subsection— (1) Military flight simulator means any... 110-181, DoD is prohibited from entering into a service contract to acquire a military flight...

48 CFR 237.102-71 - Limitation on service contracts for military flight simulators.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracts for military flight simulators. 237.102-71 Section 237.102-71 Federal Acquisition Regulations... flight simulators. (a) Definitions. As used in this subsection— (1) Military flight simulator means any... 110-181, DoD is prohibited from entering into a service contract to acquire a military flight...

48 CFR 237.102-74 - Taxonomy for the acquisition of services, and supplies and equipment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Taxonomy for the... CONTRACTING SERVICE CONTRACTING Service Contracts-General 237.102-74 Taxonomy for the acquisition of services, and supplies and equipment. See PGI 237.102-74 for further guidance on the taxonomy for the...

33 CFR 110.237 - Pacific Ocean at Waimea, Hawaii, Naval Anchorage.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Naval Anchorage. 110.237 Section 110.237 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF..., Hawaii, Naval Anchorage. (a) The Anchorage grounds. All the waters within a circle having a radius of 300.... Except in an emergency, no vessel except a Naval vessel may anchor or moor in this anchorage without...

48 CFR 237.7101 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... clause at 252.237-7015, Loss or Damage (Weight of Articles), in solicitations and contracts for laundry..., Instruction to Offerors (Bulk Weight), in solicitations for laundry services to be provided on a bulk weight basis. (c) Use the clause at 252.237-7014, Loss or Damage (Count-of-Articles), in solicitations and...

48 CFR 252.237-7015 - Loss or damage (weight of articles).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Loss or damage (weight of... of Provisions And Clauses 252.237-7015 Loss or damage (weight of articles). As prescribed in 237.7101(d), use the following clause: Loss or Damage (Weight of Articles) (DEC 1991) (a) The Contractor...

48 CFR 252.237-7015 - Loss or damage (weight of articles).

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Loss or damage (weight of... of Provisions And Clauses 252.237-7015 Loss or damage (weight of articles). As prescribed in 237.7101(d), use the following clause: Loss or Damage (Weight of Articles) (DEC 1991) (a) The Contractor...

5 CFR 838.237 - Death of the former spouse.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Death of the former spouse. 838.237... Affecting Employee Annuities Payment Procedures § 838.237 Death of the former spouse. (a) Unless the court... annuity terminates on the last day of the month before the death of the former spouse, and the former...

5 CFR 838.237 - Death of the former spouse.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Death of the former spouse. 838.237... Affecting Employee Annuities Payment Procedures § 838.237 Death of the former spouse. (a) Unless the court... annuity terminates on the last day of the month before the death of the former spouse, and the former...

5 CFR 838.237 - Death of the former spouse.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Death of the former spouse. 838.237... Affecting Employee Annuities Payment Procedures § 838.237 Death of the former spouse. (a) Unless the court... annuity terminates on the last day of the month before the death of the former spouse, and the former...

5 CFR 838.237 - Death of the former spouse.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Death of the former spouse. 838.237... Affecting Employee Annuities Payment Procedures § 838.237 Death of the former spouse. (a) Unless the court... annuity terminates on the last day of the month before the death of the former spouse, and the former...

Biokinetics of /sup 237/Np in mussels and shrimp

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guary, J.C.; Fowler, S.W.

1977-01-01

Neptunium-237 kinetics were studied in marine shrimp and mussels using a thick source alpha counting technique. Bioaccumulation of /sup 237/Np from water was relatively slow in both species, reaching whole body concentration factors of only 15 to 20 after three months. Surface adsorption was implicated in the initial uptake. Both uptake and loss of the radioisotope were not significantly affected by temperature; this may be a reflection of the physical nature of the uptake. By virtue of the large amounts of accumulated /sup 237/Np associated with the exoskeleton of shrimp, molting will play an important role in the biogeochemical cyclingmore » of this transuranic in the marine environment. Rapid growth of organisms like mussels acts to reduce the /sup 237/Np concentration in tissues during a period of decontamination.« less

Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum β-Lactamases

DOE PAGES

Adamski, Carolyn J.; Cardenas, Ana Maria; Brown, Nicholas G.; ...

2014-12-09

We report that extended-spectrum β-lactamases (ESBLs) pose a threat to public health because of their ability to confer resistance to extended-spectrum cephalosporins such as cefotaxime. The CTX-M β-lactamases are the most widespread ESBL enzymes among antibiotic resistant bacteria. Many of the active site residues are conserved between the CTX-M family and non-ESBL β-lactamases such as TEM-1, but the residues Ser237 and Arg276 are specific to the CTX-M family, suggesting that they may help to define the increased specificity for cefotaxime hydrolysis. To test this hypothesis, site-directed mutagenesis of these positions was performed in the CTX-M-14 β-lactamase. Substitutions of Ser237 andmore » Arg276 with their TEM-1 counterparts, Ala237 and Asn276, had a modest effect on cefotaxime hydrolysis, as did removal of the Arg276 side chain in an R276A mutant. The S237A:R276N and S237A:R276A double mutants, however, exhibited 29- and 14-fold losses in catalytic efficiency for cefotaxime hydrolysis, respectively, while the catalytic efficiency for benzylpenicillin hydrolysis was unchanged. Therefore, together, the Ser237 and Arg276 residues are important contributors to the cefotaximase substrate profile of the enzyme. High-resolution crystal structures of the CTX-M-14 S70G, S70G:S237A, and S70G:S237A:R276A variants alone and in complex with cefotaxime show that residues Ser237 and Arg276 in the wild-type enzyme promote the expansion of the active site to accommodate cefotaxime and favor a conformation of cefotaxime that allows optimal contacts between the enzyme and substrate. In conclusion, the conservation of these residues, linked to their effects on structure and catalysis, imply that their coevolution is an important specificity determinant in the CTX-M family.« less

SpaceX CRS-14 Prelaunch News Conference

NASA Image and Video Library

2018-04-01

In the Kennedy Space Center’s Press Site auditorium, NASA and industry leaders speak to members of the media during a prelaunch news conference for the SpaceX CRS-14 commercial resupply services mission to the International Space Station. Mike McAleenan, weather officer, 45th Weather Squadron, participates in the news conference. A Dragon spacecraft is scheduled to be launched from Space Launch Complex 40 at Cape Canaveral Air Force Station at 4:30 p.m. EST, on April 2, 2018. The SpaceX Falcon 9 rocket will lift off on the company's 14th Commercial Resupply Services mission to the space station.

Capability to Recover Plutonium-238 in H-Canyon/HB-Line - 13248

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fuller, Kenneth S. Jr.; Smith, Robert H. Jr.; Goergen, Charles R.

2013-07-01

Plutonium-238 is used in Radioisotope Thermoelectric Generators (RTGs) to generate electrical power and in Radioisotope Heater Units (RHUs) to produce heat for electronics and environmental control for deep space missions. The domestic supply of Pu-238 consists of scrap material from previous mission production or material purchased from Russia. Currently, the United States has no significant production scale operational capability to produce and separate new Pu-238 from irradiated neptunium-237 targets. The Department of Energy - Nuclear Energy is currently evaluating and developing plans to reconstitute the United States capability to produce Pu-238 from irradiated Np-237 targets. The Savannah River Site hadmore » previously produced and/or processed all the Pu-238 utilized in Radioisotope Thermoelectric Generators (RTGs) for deep space missions up to and including the majority of the plutonium for the Cassini Mission. The previous full production cycle capabilities included: Np- 237 target fabrication, target irradiation, target dissolution and Np-237 and Pu-238 separation and purification, conversion of Np-237 and Pu-238 to oxide, scrap recovery, and Pu-238 encapsulation. The capability and equipment still exist and could be revitalized or put back into service to recover and purify Pu-238/Np-237 or broken General Purpose Heat Source (GPHS) pellets utilizing existing process equipment in HB-Line Scrap Recovery, and H-Canyon Frame Waste Recovery processes. The conversion of Np-237 and Pu-238 to oxide can be performed in the existing HB-Line Phase-2 and Phase- 3 Processes. Dissolution of irradiated Np-237 target material, and separation and purification of Np-237 and Pu-238 product streams would be possible at production rates of ∼2 kg/month of Pu-238 if the existing H-Canyon Frames Process spare equipment were re-installed. Previously, the primary H-Canyon Frames equipment was removed to be replaced: however, the replacement project was stopped. The spare equipment is stored and still available for installation. Out of specification Pu-238 scrap material can be purified and recovered by utilizing the HB-Line Phase- 1 Scrap Recovery Line and the Phase-3 Pu-238 Oxide Conversion Line along with H-Canyon Frame Waste Recovery process. In addition, it also covers and describes utilizing the Phase-2 Np-237 Oxide Conversion Line, in conjunction with the H-Canyon Frames Process to restore the H-Canyon capability to process and recover Np-237 and Pu-238 from irradiated Np-237 targets and address potential synergies with other programs like recovery of Pu-244 and heavy isotopes of curium from other target material. (authors)« less

75 FR 4428 - Advisory Committee On Reactor Safeguards; Revised Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards; Revised Meeting Notice The Agenda for the 569th ACRS meeting, scheduled to be held on February 4-6, 2010, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on Thursday, January 21...

75 FR 72844 - Advisory Committee on Reactor Safeguards; Revised Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-26

... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Revised Meeting Notice The Agenda for the 578th ACRS meeting, scheduled to be held on December 2-4, 2010, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on Wednesday, November 17...

76 FR 61118 - Advisory Committee on Reactor Safeguards; Revised Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Revised Meeting Notice The Agenda for the 587th ACRS meeting, scheduled to be held on October 6-8, 2011, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on September 26, 2011 (76...

76 FR 51398 - Importer of Controlled Substances; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

..., Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616-3466, made application by renewal..., objections, or requests for any hearings will be accepted on any application for registration or re... class of any controlled substance in schedule I or II are, and will continue to be, required to...

Proceedings of the 13th Annual International Conference on Outdoor Recreation & Education (Jackson Hole, Wyoming, November 1-6, 1999).

ERIC Educational Resources Information Center

Harwell, Rick, Ed.; Emmons, Karin, Ed.

This proceedings contains papers, abstracts of papers, and descriptions of professional development workshops at the 1999 International Conference of the Association for Outdoor Recreation and Education (AORE). Following conference schedules and session information, substantive entries include: "The 1999 National Outdoor Book Awards";…

Performance Analysis of Wireless Networks for Industrial Automation-Process Automation (WIA-PA)

DTIC Science & Technology

2017-09-01

electrical, water and wastewater, oil and natural gas, chemical, transportation, pharmaceutical, pulp and paper, food and beverage, and discrete...scheduling method for isa100.11a,” in 2013 11th IEEE International Conference on Industrial Informatics (INDIN), 2013, pp. 649–654. [24] Y. Wei and D.-S

KSC-2011-1632

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. - In the White Room at Launch Pad 39A at NASA's Kennedy Space Center in Florida, United Space Alliance spacesuit technicians help STS-133 Commander Steve Lindsey put on the parachute for his launch-and-entry suit before he enters space shuttle Discovery through the crew hatch in the background. Lindsey will be making his fifth spaceflight and third aboard Discovery. Since his most recent mission -- STS-121 in 2006 -- Lindsey served as chief of the Astronaut Office at NASA's Johnson Space Center in Houston. Scheduled to lift off Feb. 24 at 4:50 p.m. EST, Discovery and its crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Sandra Joseph and Kevin O'Connell

48 CFR 237.102-74 - Taxonomy for the acquisition of services.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Taxonomy for the... Service Contracts-General 237.102-74 Taxonomy for the acquisition of services. See PGI 237.102-74 for OUSD(AT&L) DPAP memorandum, “Taxonomy for the Acquisition of Services,” dated November 23, 2010. [75 FR...

48 CFR 237.102-74 - Taxonomy for the acquisition of services.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Taxonomy for the... Service Contracts-General 237.102-74 Taxonomy for the acquisition of services. See PGI 237.102-74 for OUSD(AT&L) DPAP memorandum, “Taxonomy for the Acquisition of Services,” dated November 23, 2010. [75 FR...

48 CFR 237.102-74 - Taxonomy for the acquisition of services.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Taxonomy for the... Service Contracts-General 237.102-74 Taxonomy for the acquisition of services. See PGI 237.102-74 for OUSD(AT&L) DPAP memorandum, “Taxonomy for the Acquisition of Services,” dated November 23, 2010. [75 FR...

Method for detecting and correcting for isotope burn-in during long-term neutron dosimetry exposure

DOEpatents

Ruddy, Francis H.

1988-01-01

A method is described for detecting and correcting for isotope burn-in during-long term neutron dosimetry exposure. In one embodiment, duplicate pairs of solid state track recorder fissionable deposits are used, including a first, fissionable deposit of lower mass to quantify the number of fissions occuring during the exposure, and a second deposit of higher mass to quantify the number of atoms of for instance .sup.239 Pu by alpha counting. In a second embodiment, only one solid state track recorder fissionable deposit is used and the resulting higher track densities are counted with a scanning electron microscope. This method is also applicable to other burn-in interferences, e.g., .sup.233 U in .sup.232 Th or .sup.238 Pu in .sup.237 Np.

Cardiac Valve Noise Reduction by Non-Drug Interventions Improves the Sleep Quality of Patients after Mechanical Cardiac Valve Implantation.

PubMed

Lin, Yanjuan; Xu, Le; Huang, Xizhen; Jiang, Fei; Lin, Fen; Ye, Qingyang; Lin, Jianling

2016-01-01

To investigate the effects of non-drug interventions on the sleep quality of patients after mechanical cardiac valve implantation. In this prospective, randomized, controlled trial, 64 patients scheduled for mechanical mitral valve replacement were recruited. Patients underwent cognitive behavioral therapy and wore noise cancelling earplugs and eye mask. Sleep quality was evaluated on the 4th after admission and the 5th days after operation. The primary outcome was the total sleep quality score differences between the 4th day after admission and the 5th day after operation. All patients had been suffering from poor sleep quality for a month before admission. There was no difference between both groups on the 4th day after admission. Overall sleep quality in the intervention group was better than in the control group on the 5th day after operation. The subjective sleep quality of the patients in each group was significantly lower on the 5th day after the operation than on the 4th day after admission (P <0.05). Non-drug intervention could improve the sleep quality of patients after mechanical cardiac valve implantation and help the postoperative recovery of the patients. ( ChiCTR-TRC-14004405, 21 March 2014.).

Auspicious birth dates among Chinese in California.

PubMed

Almond, Douglas; Chee, Christine Pal; Sviatschi, Maria Micaela; Zhong, Nan

2015-07-01

The number eight is considered lucky in Chinese culture, e.g. the Beijing Olympics began at 8:08 pm on 8/8/2008. Given the potential for discretion in selecting particular dates of labor induction or scheduled Cesarean section (C-section), we consider whether Chinese-American births in California occur disproportionately on the 8th, 18th, or 28th day of the month. We find 2.3% "too many" Chinese births on these auspicious birth dates, whereas Whites show no corresponding increase. The increase in Chinese births is driven by higher parity C-sections: the number of repeat C-sections is 6% "too high" on auspicious birth dates. Sons born to Chinese parents account for the entire increase; daughter deliveries do not seem to be timed to achieve "lucky" birth dates. We also find avoidance of repeat C-section deliveries on the 4th, 14th, and 24th of the month, considered unlucky in Chinese culture. Finally, we replicate earlier work finding that Friday the 13th delivery dates are avoided and document a particularly large decrease among Chinese. For Whites and Chinese in California, mothers with higher levels of education are particularly likely to avoid delivering on the 13th. Copyright © 2015 Elsevier B.V. All rights reserved.

Early Development of the First Earth Venture Mission: How CYGNSS Is Using Engineering Models to Validate the Design

NASA Technical Reports Server (NTRS)

Wells, James; Scherrer, John; Van Noord, Jonathan; Law, Richard

2015-01-01

In response to the recommendations made in the National Research Council' s Ear th Science and Applications 2007 Decadal Sur vey, NASA has initiated the Ear th Venture line of mission oppor tunities. The fir st orbital mission chosen for this competitively selected, cost and schedule constrained, Pr incipal Investigator -led oppor tunity is the CYclone Global Navigation Satellite System (CYGNSS). The goal of CYGNSS is to understand the coupling between ocean sur face proper ties, moist atmospher ic thermodynamics, radiation, and convective dynamics in the inner core of a tropical cyclone. The CYGNSS mission is compr ised of eight Low Ear th Obser ving (LEO) micr osatellites that use GPS bi-static scatterometry to measure ocean sur face winds.

Status of the Neutron Capture Measurement on 237Np with the DANCE Array at LANSCE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Esch, E.-I.; Bond, E.M.; Bredeweg, T. A.

2005-05-24

Neptunium-237 is a major constituent of spent nuclear fuel. Estimates place the amount of 237Np bound for the Yucca Mountain high-level waste repository at 40 metric tons. The Department of Energy's Advanced Fuel Cycle Initiative program is evaluating methods for transmuting the actinide waste that will be generated by future operation of commercial nuclear power plants. The critical parameter that defines the transmutation efficiency of actinide isotopes is the neutron fission-to-capture ratio for the particular isotope in a given neutron spectrum. The calculation of transmutation efficiency therefore requires accurate fission and capture cross sections. Current 237Np evaluations available for transmutermore » system studies show significant discrepancies in both the fission and capture cross sections in the energy regions of interest. Herein we report on 237Np (n,{gamma}) measurements using the recently commissioned DANCE array.« less

29 CFR 779.237 - Enterprise engaged in commerce or in the production of goods for commerce.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Enterprise engaged in commerce or in the production of goods for commerce. 779.237 Section 779.237 Labor Regulations Relating to Labor (Continued) WAGE AND... commerce or in the production of goods for commerce. Under section 3(s) the “enterprise” to be covered must...

29 CFR 779.237 - Enterprise engaged in commerce or in the production of goods for commerce.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Enterprise engaged in commerce or in the production of goods for commerce. 779.237 Section 779.237 Labor Regulations Relating to Labor (Continued) WAGE AND... commerce or in the production of goods for commerce. Under section 3(s) the “enterprise” to be covered must...

29 CFR 779.237 - Enterprise engaged in commerce or in the production of goods for commerce.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Enterprise engaged in commerce or in the production of goods for commerce. 779.237 Section 779.237 Labor Regulations Relating to Labor (Continued) WAGE AND... commerce or in the production of goods for commerce. Under section 3(s) the “enterprise” to be covered must...

29 CFR 779.237 - Enterprise engaged in commerce or in the production of goods for commerce.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Enterprise engaged in commerce or in the production of goods for commerce. 779.237 Section 779.237 Labor Regulations Relating to Labor (Continued) WAGE AND... commerce or in the production of goods for commerce. Under section 3(s) the “enterprise” to be covered must...

29 CFR 779.237 - Enterprise engaged in commerce or in the production of goods for commerce.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Enterprise engaged in commerce or in the production of goods for commerce. 779.237 Section 779.237 Labor Regulations Relating to Labor (Continued) WAGE AND... commerce or in the production of goods for commerce. Under section 3(s) the “enterprise” to be covered must...

Neutron induced fission of 237Np - status, challenges and opportunities

NASA Astrophysics Data System (ADS)

Ruskov, Ivan; Goverdovski, Andrei; Furman, Walter; Kopatch, Yury; Shcherbakov, Oleg; Hambsch, Franz-Josef; Oberstedt, Stephan; Oberstedt, Andreas

2018-03-01

Nowadays, there is an increased interest in a complete study of the neutron-induced fission of 237Np. This is due to the need of accurate and reliable nuclear data for nuclear science and technology. 237Np is generated (and accumulated) in the nuclear reactor core during reactor operation. As one of the most abundant long-lived isotopes in spent fuel ("waste"), the incineration of 237Np becomes an important issue. One scenario for burning of 237Np and other radio-toxic minor actinides suggests they are to be mixed into the fuel of future fast-neutron reactors, employing the so-called transmutation and partitioning technology. For testing present fission models, which are at the basis of new generation nuclear reactor developments, highly accurate and detailed neutron-induced nuclear reaction data is needed. However, the EXFOR nuclear database for 237Np on neutron-induced capture cross-section, σγ, and fission cross-section, σf, as well as on the characteristics of capture and fission resonance parameters (Γγ, Γf, σoΓf, fragments mass-energy yield distributions, multiplicities of neutrons vn and γ-rays vγ), has not been updated for decades.

Prediction of new Quarks, Generations & low Mass Quarks

NASA Astrophysics Data System (ADS)

Lach, Theodore

2003-04-01

The CBM (model) of the nucleus has resulted in the prediction of two new quarks, an "up" quark of mass 237.31 MeV/c2 and a "dn" quark of mass 42.392 MeV/c2. These two new predicted quarks helped to determine that the masses of the quarks and leptons are all related by a geometric progression relationship. The mass of each quark or lepton is just the "geometric mean" of two related elementary particles, either in the same generation or in the same family. This numerology predicts the following masses for the electron family: 0.511000 (electron), 7.74 (predicted), 117.3, 1778.4 (tau), 26950.1 MeV. The geometric ratio of this progression is 15.154 (e to the power e). The mass of the tau in this theory agrees very well with accepted values. This theory suggests that all the "dn like" quarks have a mass of just 10X multiples of 4.24 MeV (the mass of the "d" quark). The first 3 "up like" quark masses are 38, 237.31 and 1500 MeV. This theory also predicts a new heavy generation with a lepton mass of 27 GeV, a "dn like" quark of 42.4 GeV, and an "up like" quark of 65 GeV. Significant evidence already exists for the existence of these new quarks, and lepton. Ref. Masses of the Sub-Nuclear Particles, nucl-th/ 0008026, @ http://xxx.lanl.gov. Infinite Energy, Vol 5, issue 30.

2D model of the Nucleus

NASA Astrophysics Data System (ADS)

Lach, Theodore M.

2003-10-01

The CBM (model) of the nucleus has resulted in the prediction of two new quarks, an "up" quark of mass 237.31 MeV/c2 and a "dn" quark of mass 42.392 MeV/c2. These two new predicted quarks helped to determine that the masses of the quarks and leptons are all related by a geometric progression relationship. The mass of each quark or lepton is just the "geometric mean" of two related elementary particles, either in the same generation or in the same family. This numerology predicts the following masses for the electron family: 0.511000 (electron), 7.74 (predicted), 117.3, 1778.4 (tau), 26950.1 MeV. The geometric ratio of this progression is 15.154 (e to the power e). The mass of the tau in this theory agrees very well with accepted values. This theory suggests that all the "dn like" quarks have a mass of just 10X multiples of 4.24 MeV (the mass of the "d" quark). The first 3 "up like" quark masses are 38, 237.31 and 1500 MeV. This theory also predicts a new heavy generation with a lepton mass of 27 GeV, a "dn like" quark of 42.4 GeV, and an "up like" quark of 65 GeV. Significant evidence already exists for the existence of these new quarks, and lepton. Ref. Masses of the Sub-Nuclear Particles, nucl-th/ 0008026, @ http://xxx.lanl.gov. Infinite Energy, Vol 5, issue 30.

47 CFR 54.1306 - Updating Information Submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2014 CFR

2014-10-01

... incumbent local exchange carrier subject to § 54.1301(a) may update the information submitted to the... on a rolling year basis according to the schedule. (1) Submit data covering the last nine months of... September 30th of the existing year; (2) Submit data covering the last six months of the previous calendar...

76 FR 51399 - Importer of Controlled Substances; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

.... Therefore, in accordance with 21 CFR 1301.34(a), this is notice that on May 4, 2011, Cambrex Charles City, 1205 11th Street, Charles City, Iowa 50616-3466, made application by renewal to the Drug Enforcement... schedule I or II are, and will continue to be, required to demonstrate to the Deputy Assistant...

Looking for something new? Check out background results of potential new cultivars for California

USDA-ARS?s Scientific Manuscript database

This report compiles basic background information on the scion and rootstock varieties most recently released or scheduled for release by the CCPP. Cultivars are organized by type and in the same order as the CCPP budwood order form, and then by Variety index (VI) number with the earliest ones on th...

Urban Options Solar Greenhouse Demonstration Project. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cipparone, L.

1980-10-15

The following are included: the design process, construction, thermal performance, horticulture, educational activities, and future plans. Included in appendices are: greenhouse blueprints, insulating curtain details, workshop schedules, sample data forms, summary of performance calculations on the Urban Options Solar Greenhouse, data on vegetable production, publications, news articles on th Solar Greenhouse Project, and the financial statement. (MHR)

Biennial Conference on Chemical Education, Abstracts (11th, Atlanta, Georgia, August 5-9, 1990).

ERIC Educational Resources Information Center

Mellon, E. K.; Pulliam, E. J.

This publication includes more than 470 abstracts of papers scheduled to be presented at a chemical education conference. Topics of the papers include: (1) human impact on the environment; (2) technology; (3) forensic science; (4) paper chemistry; (5) computer interfacing, software, videodisc and graphics; (6) faculty enhancement programs; (7)…

Distant Voices, Shared Dreams. Proceedings of the Annual Alaska Bilingual/Multicultural Education Conference (14th, Anchorage, Alaska, February 3-5, 1988).

ERIC Educational Resources Information Center

Alaska State Dept. of Education, Juneau. Bilingual/Bicultural Education Programs.

These conference proceedings include a conference schedule, numerous photographs from the conference and from its events, and these papers: "Role of Literature as a Source of History, Values and Identity" (keynote address, Edna Ahgeak MacLean); "Motivating Young People to Succeed" (Howard Rainer); "Empowering Minority…

SOT Risk Assessment: Complex mixtures of anti-androgens at concentrations below individual chemical effect levels produces reproductive tract malformations in the male rat

EPA Science Inventory

This product is an invited webinar to the Society of Toxicology Risk Assessment Specialty Section (co-hosted by the Mixtures Specialty Section) as part of their monthly webinar series. The webinar is scheduled for 3:00PM on Wednesday September 13th.

SpaceX/Dragon CRS-12 What's on Board Science Briefing

NASA Image and Video Library

2017-08-13

The briefing focused on research planned for launch to the International Space Station. The scientific materials and supplies will be aboard a Dragon spacecraft scheduled for launch from Kennedy’s Launch Complex 39A on Aug. 14 atop a SpaceX Falcon 9 rocket on the company's 12th Commercial Resupply Services mission to the space station.

Aventuras en Mexico: Proceedings of the International Conference on Outdoor Recreation and Education (ICORE) (11th, Merida, Mexico, November 6-8, 1997).

ERIC Educational Resources Information Center

Jones, Rob, Comp.; Wilkinson, Brian, Comp.

This proceedings contains 21 papers and panel summaries from the 1997 International Conference on Outdoor Recreation and Education. Introductory items include conference highlights, history, and schedule overview. Entries are: "Outdoor Leadership 2000" (Simon Priest); "Permits To Operate: Doing What We Do with the Proper…

5 CFR 591.237 - Under what circumstances may employees on leave or travel receive a COLA and/or post differential?

Code of Federal Regulations, 2010 CFR

2010-01-01

... leave or travel receive a COLA and/or post differential? 591.237 Section 591.237 Administrative... circumstances may employees on leave or travel receive a COLA and/or post differential? (a) An employee on leave or travel may receive a COLA or post differential only if the agency anticipates that the employee...

5 CFR 591.237 - Under what circumstances may employees on leave or travel receive a COLA and/or post differential?

Code of Federal Regulations, 2014 CFR

2014-01-01

... leave or travel receive a COLA and/or post differential? 591.237 Section 591.237 Administrative... circumstances may employees on leave or travel receive a COLA and/or post differential? (a) An employee on leave or travel may receive a COLA or post differential only if the agency anticipates that the employee...

5 CFR 591.237 - Under what circumstances may employees on leave or travel receive a COLA and/or post differential?

Code of Federal Regulations, 2013 CFR

2013-01-01

... leave or travel receive a COLA and/or post differential? 591.237 Section 591.237 Administrative... circumstances may employees on leave or travel receive a COLA and/or post differential? (a) An employee on leave or travel may receive a COLA or post differential only if the agency anticipates that the employee...

5 CFR 591.237 - Under what circumstances may employees on leave or travel receive a COLA and/or post differential?

Code of Federal Regulations, 2011 CFR

2011-01-01

... leave or travel receive a COLA and/or post differential? 591.237 Section 591.237 Administrative... circumstances may employees on leave or travel receive a COLA and/or post differential? (a) An employee on leave or travel may receive a COLA or post differential only if the agency anticipates that the employee...

5 CFR 591.237 - Under what circumstances may employees on leave or travel receive a COLA and/or post differential?

Code of Federal Regulations, 2012 CFR

2012-01-01

... leave or travel receive a COLA and/or post differential? 591.237 Section 591.237 Administrative... circumstances may employees on leave or travel receive a COLA and/or post differential? (a) An employee on leave or travel may receive a COLA or post differential only if the agency anticipates that the employee...

NADH Dehydrogenase Subunit-2 237 Leu/Met Polymorphism Modulates the Effects of Coffee Consumption on the Risk of Hypertension in Middle-Aged Japanese Men

PubMed Central

Kokaze, Akatsuki; Ishikawa, Mamoru; Matsunaga, Naomi; Karita, Kanae; Yoshida, Masao; Ohtsu, Tadahiro; Shirasawa, Takako; Sekii, Hideaki; Ito, Taku; Kawamoto, Teruyoshi; Takashima, Yutaka

2009-01-01

Background Habitual coffee consumption has been reported to lower blood pressure in the Japanese population. The NADH dehydrogenase subunit-2 237 leucine/methionine (ND2-237 Leu/Met) polymorphism is associated with longevity and modifies the effects of alcohol consumption on blood pressure in the Japanese population. The objective of this study was to determine whether this polymorphism also modifies the effects of coffee consumption on blood pressure or the risk of hypertension in middle-aged Japanese men. Methods A total of 398 men (mean age ± standard deviation, 53.8 ± 7.8 years) were selected from among individuals visiting the hospital for regular medical check-ups. Hypertension was defined as a systolic blood pressure ≥140 mm Hg, diastolic blood pressure ≥90 mm Hg, or antihypertensive drug treatment. Polymerase chain reaction-restriction fragment length polymorphism using the restriction enzyme AluI was performed to determine ND2-237 Leu/Met genotype. Results In subjects with ND2-237Leu, coffee consumption was significantly and negatively associated with diastolic blood pressure (P = 0.007). The odds ratio (OR) for hypertension was significantly lower in subjects with ND2-237Leu who consumed 2 or 3 cups of coffee per day than in those who consumed less than 1 cup of coffee per day (OR, 0.517; 95% confidence interval [CI], 0.276 to 0.968; P = 0.039). After adjustment, the OR remained significant (OR = 0.399; 95% CI, 0.184 to 0.869; P = 0.020). Moreover, after adjustment, the OR was significantly lower in subjects with ND2-237Leu who consumed more than 4 cups of coffee per day than in those who consumed less than 1 cup of coffee per day (OR, 0.246; 95% CI, 0.062 to 0.975; P = 0.046). However, the association between ND2-237Met genotype and hypertension did not depend on coffee consumption. Conclusions The present results suggest that the ND2-237 Leu/Met polymorphism modulates the effects of coffee consumption on hypertension risk in middle-aged Japanese men. PMID:19667492

Korzun after EVA 1 completed

NASA Image and Video Library

2002-08-14

ISS005-E-09725 (14 August 2002) --- Cosmonaut Valery G. Korzun, Expedition Five mission commander, attired in his thermal undergarment prior to donning a Russian Orlan spacesuit, prepares for an upcoming session of extravehicular activity (EVA) from the Pirs docking compartment on the International Space Station (ISS). The spacewalk is scheduled for August 16, 2002, which will be the 42nd spacewalk at the station and the 17th based out of the station. Korzun and astronaut Peggy A. Whitson, flight engineer, will install six debris panels on the Zvezda Service Module. The panels are designed to shield Zvezda from potential space debris impacts. Korzun, who represents Rosaviakosmos, is also scheduled for a spacewalk on August 22, 2002.

Schedule Analytics

DTIC Science & Technology

2016-04-30

1990’s to Today MAIS MDAP 12.75 Years 7.9 Years 43 Months 68 Months 42 Months A B C IOC 31m 41m 23m FDD A B C A B C Materiel...to FDD 26 2m 9m 16m 41m 72m Months MS A to MS B MS B to MS C MS C to FDD 10 20 30 40 50 60 70 80 90...vs. Schedule 0 10 20 30 40 50 60 70 80 90 100 110 120 >$1B $500M-$1B <$500M M on th s MAIS MS A – MS B MS B – MS C MS C – FDD Total © 2016 The MITRE

78 FR 69742 - Commercial Space Transportation Advisory Committee-Open Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

...Pursuant to Section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463, 5 U.S.C. App. 2), notice is hereby given of a meeting of the Commercial Space Transportation Advisory Committee (COMSTAC). The meeting will take place on Tuesday, December 10, 2013, from 8:00 a.m. to 5:00 p.m., and Wednesday, December 11, from 8:30 a.m. to 2:00 p.m., at the National Housing Center, 1201 15th Street NW., Washington, DC 20005. This will be the 58th meeting of the COMSTAC. The proposed schedule for the COMSTAC working group meetings on December 10 is below:

KSC-2009-2016

NASA Image and Video Library

2009-03-10

CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Steve Swanson has the final fitting of his launch and entry suit. Swanson is making his second shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

Determination of traces of 237Np in environmental samples by ICP-MS after separation using TOA extraction chromatography.

PubMed

Ji, Y Q; Li, J Y; Luo, S G; Wu, T; Liu, J L

2001-09-01

A simple, rapid, cost-efficient, and robust method for separation of 237Np with an extraction chromatographic column (TOA: tri-n-octylamine on Teflon powder) is outlined in detail and further improved for direct ICP-MS analysis. The column efficiently retained 237Np in 2 mol L(-1) HNO3 medium and all of the 237Np was easily eluted with 0.02 mol L(-1) oxalic acid in 0.16 mol L(-1) HNO3 at 95 degrees C. The separated solutions were free from most matrix elements and were aspirated into the ICP-MS directly. The decontamination factor for 238U is more than 10(4). The instrumental detection limit for 237Np was 0.46 pg mL(-1), which corresponds to 1.2 x 10(-5) Bq mL(-1). The method is more rapid than traditional radiometric techniques. It is also considered to be more suitable for environmental monitoring than existing methods based on TOA.

Behavior of flavonols and carotenoids of minimally processed kale leaves during storage in passive modified atmosphere packaging.

PubMed

Kobori, C N; Huber, L S; Sarantópoulos, C I G L; Rodriguez-Amaya, D B

2011-03-01

Minimally processed kale leaves were packed in passive modified atmosphere and stored at 3 conditions: 1 °C in the dark and 11 °C with or without light exposure. The products were evaluated during storage in terms of headspace gas composition, sensory attributes, flavonol, and carotenoid contents. The sensory quality decreased slightly during 17 d at 1 °C in the dark. At 11 °C, the vegetable shelf life was predicted to be 6 d in the dark and 3 d with light. Quercetin and kaempferol were stable during storage for 15 d at 1 °C in the absence of light. At 11 °C in the dark, quercetin was stable during 10 d, increasing slightly on the 8th day. Kaempferol decreased up to the 5th day but increased on the 8th day, decreasing again on the 10th day. After 5 d at 11 °C under light, the flavonol levels were significantly higher than those of the initial values. Neoxanthin and violaxanthin did not change significantly after 15 d at 1 °C in the dark. Lutein and β-carotene, however, decreased 7.1% and 11.3%, respectively. At 11 °C in the dark, neoxanthin, violaxanthin, lutein, and β-carotene decreased 16.1%, 13.2%, 24.1%, and 23.7% after 10 d, respectively. At 11 °C under light, neoxanthin and lutein had a slight increase while violaxanthin and β-carotene decreased 23.1% and 16.5% after 5 d. Practical Application:  Passive modified atmosphere packaging together with refrigeration can extend the shelf life of minimally processed kale, retaining the health-promoting compounds, flavonols and carotenoids. Quercetin, kaempferol, neoxanthin, and violaxanthin are stable and lutein and β-carotene slightly reduced.

[Inequalities regarding death in the past].

PubMed

Blum, A; Houdaille, J

1989-01-01

Was mortality differentiated socio-economically in past centuries, as it is nowadays? The issue has been hotly debated. Certain demographers admitted that, periods of famine excepted, the death risk was evenly distributed among the ancient populations, regardless of wealth, instruction or social status. On the other hand, the research project currently carried out at the French National Institute of Demographic Studies is evidencing wide mortality social differentials in the 19th century. In Paris, male life expectancy at the age of 40 reached 29.7 years for the nobility and bourgeoisie, but decreased to 25.6 years among merchants and 23.7 years among workers and day-labourers. Generally speaking, regional differentials were less pronounced than socioeconomic differentials. Mortality decline was found among the elites: life expectancy at 40 of the Knights of the Holy Spirit, for instance, increased to 30.8 years in the 18th century, from 27.8 years in the 16th century. The same life expectancy today (at 40 years of age) reaches 35.7 years among French professionals. The main problem with this kind of research is how to identify and collect relevant information. The researchers make use here of marriage registers from the past century. These registers recorded not only particulars of the married couple but also those of their parents (occupation, age, and date of death, if any). This information allows the calculation of mortality rates (and life expectancy) of ancient birth cohorts in various occupational groups. The primary condition is that the registers have been well kept and soundly stored until now. This is the case in certain city halls: the 4th arrondissement of Paris (1860-1863), Ivry-sur-Seine (1817-1823)... etc...

Acute Problems of Virology and Prophylaxis of Viral Diseases,

DTIC Science & Technology

Contents: Immunogenic activity of attenuated variant of langat virus in experiments with monkeys; Evaluation of various methods of immunization of...monkeys by variant Tr-21-237 of the langat virus; A study of residual pathogenicity of attenuated variant Tr-21-237 of langat virus in experiments...with monkeys; Pathomorphological indexes of residual neurovirulence of the attenuated variant Tr-21-237 of langat virus in experiments with monkeys.

KSC-06pd2050

NASA Image and Video Library

2006-09-06

KENNEDY SPACE CENTER, FLA. - The morning sky lightens behind Space Shuttle Atlantis while lights on the fixed service structure (FSS) still illuminate the orbiter on Launch Pad 39B. Atlantis was originally scheduled to launch at 12:29 p.m. EDT on this date, but a 24-hour scrub was called by mission managers due to a concern with Fuel Cell 1. Seen poised above the orange external tank is the vent hood (known as the "beanie cap") at the end of the gaseous oxygen vent arm. Vapors are created as the liquid oxygen in the external tank boil off. The hood vents the gaseous oxygen vapors away from the space shuttle vehicle. Extending from the FSS to Atlantis is the orbiter access arm with the White Room at the end. The White Room provides entry into the orbiter through the hatch. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Troy Cryder

KSC-06pd2053

NASA Image and Video Library

2006-09-06

KENNEDY SPACE CENTER, FLA. - The morning sky lightens behind Space Shuttle Atlantis while lights on the fixed service structure (FSS) still illuminate the orbiter on Launch Pad 39B. Atlantis was originally scheduled to launch at 12:29 p.m. EDT on this date, but a 24-hour scrub was called by mission managers due to a concern with Fuel Cell 1. Seen poised above the orange external tank is the vent hood (known as the "beanie cap") at the end of the gaseous oxygen vent arm. Vapors are created as the liquid oxygen in the external tank boil off. The hood vents the gaseous oxygen vapors away from the space shuttle vehicle. Extending from the FSS to Atlantis is the orbiter access arm with the White Room at the end. The White Room provides entry into the orbiter through the hatch. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Troy Cryder

Fibroblast Activation Protein-Alpha, a Serine protease that Facilitates Metastasis by Modification of Diverse Microenvironments

DTIC Science & Technology

2009-10-01

pyrrolidine (LAF-237, vildagliptin ). Both boroPro compounds are effective against FAP at nanomolar concentrations; however, micromolar LAF-237 is...dependent insulinotropic polypeptide (GIP) that are substrates for DPPIV. NVP LAF-237 or vildagliptin is one of the DPPIV inhibitors approved for type 2...peptide truncation by Tumor growth is promoted by catalytically-inactive FAP 24 Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl

Manganese-Chromium Isotope Systematics of Ivuna, Kainsaz and Other Carbonaceous Chondrites

NASA Technical Reports Server (NTRS)

Shukolyukov, A.; Lugmair, G. W.; Bogdanovski, O.

2003-01-01

We have shown earlier that the bulk samples of carbonaceous chondrites [CC] reveal excesses in both Cr-53 (Cr-53*) and Cr-54 (Cr-54*) as compared to the terrestrial standard value. The Cr-53/52 ratios in bulk samples of Orgueil (CI), Murray (CM), Allende (CV), and the Bencubbin/CH-like meteorite Hammadah Al Hambra 237 (HH237) are correlated with the respective Mn/Cr ratios. In contrast to CC, HH237 is characterized by a deficit of Cr-53 (-0.15 +/- 0.10(epsilon)) at a low Mn/Cr ratio of 0.07. The HH237 data point, however, falls on the CC line. Here we report new Mn-53 - Cr-53 results for the CC Kainsaz (CO) and Ivuna (CI).

78 FR 64013 - Importer of Controlled Substances; Notice of Application; Cambrex Charles City, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... Application; Cambrex Charles City, Inc. Pursuant to Title 21 Code of Federal Regulations 1301.34(a), this is notice that on July 24, 2013, Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616-3466... class of any controlled substance in schedules I or II are, and will continue to be, required to...

European Scientific Notes. Volume 34, Number 12,

DTIC Science & Technology

1980-12-31

protein and prevention of decompression sickness interactions and on vertebrate neuron by drugs . electrophysiology, evoked responses, and As mentioned...discussion of posters by scheduling theoretical models for the interaction of meetings late in the afternoons following molecular oxygen and related oxygen...appear to be quite difficult, because of the variety of frictional effects and Linkbpin Institute of Technology (LiTH) inter-segmental interactions which

77 FR 9927 - Filing Dates for the Arizona Special Election in the 8th Congressional District

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

... special election. SUMMARY: Arizona has scheduled elections on April 17, 2012, and June 12, 2012, to fill... file a 12-day Pre-Primary Report. Committees required to file reports in connection with both the Special Primary and Special General Election on June 12, 2012, shall file a 12-day Pre-Primary Report, a...

[Breeding hygiene regimen and fertility performance in a swine herd of 400].

PubMed

Scharfe, S; Elze, K; Kraut, G; Gruhle, J

1997-04-01

A specific breeding schedule and the subsequent reproductive performance in a 400 swine breeding herd over five years is described. The reduction of the nursing time from 49 to 28 days increased the number of litters per anno to 2.4 and of weaned piglets by six. The reproductive management is based on the 7-day-breeding schedule. Each week 22 to 23 animals are inseminated, among them eight gilts every 14 days. Mating gilts only every 14 days reduce the cost for transportation. The zoo- and biotechnique is as follows: Sows: weaning on Wednesday; 24 h later 900 IE pregnant mare serum gonadotropin (PMSG) i.m., artificial insemination (AI) on Monday or Tuesday (two times), pregnancy diagnosis by transcutaneous ultrasonography on day 23/24 post insemination. Gilts: transportation (gilts are bought-in) exactly four weeks before insemination; on Saturday/ Sunday transportation induced heat; 23 days after transportation (18th/19th day of female cycle), on Friday 900 IE PMSG (with sows simultaneously); on Monday 150 micrograms GnRH-analogue i.m.; on Wednesday/Thursday AI (two times; the 2nd AI 14 h after the first), pregnancy diagnosis by transcutaneous ultrasonography on day 23/24 post insemination.

KSC-2011-1598

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. - In the Operations and Checkout Building (O&C) at NASA's Kennedy Space Center in Florida, the astronauts of space shuttle Discovery's STS-133 crew put on their launch-and-entry suits and check the fit of their helmets and gloves before heading to the Astrovan for the ride to Launch Pad 39A. Commander Steve Lindsey, seen here, will be making his fifth spaceflight and third aboard Discovery. Since his most recent mission -- STS-121 in 2006 -- Lindsey served as chief of the Astronaut Office at NASA's Johnson Space Center in Houston. Scheduled to lift off Feb. 24 at 4:50 p.m. EST, Discovery and its crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

48 CFR 237.7302 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Development Laboratories 237.7302 General. Generally, agencies will acquire services of students at institutions of higher learning by contract between a nonprofit organization employing the student and the...

7 CFR 1280.237 - Rules and Regulations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Miscellaneous § 1280.237 Rules and...

alpha Arg-237 in Methylophilus methylotrophus (sp. W3A1) electron-transferring flavoprotein affords approximately 200-millivolt stabilization of the FAD anionic semiquinone and a kinetic block on full reduction to the dihydroquinone.

PubMed

Talfournier, F; Munro, A W; Basran, J; Sutcliffe, M J; Daff, S; Chapman, S K; Scrutton, N S

2001-06-08

The midpoint reduction potentials of the FAD cofactor in wild-type Methylophilus methylotrophus (sp. W3A1) electron-transferring flavoprotein (ETF) and the alphaR237A mutant were determined by anaerobic redox titration. The FAD reduction potential of the oxidized-semiquinone couple in wild-type ETF (E'(1)) is +153 +/- 2 mV, indicating exceptional stabilization of the flavin anionic semiquinone species. Conversion to the dihydroquinone is incomplete (E'(2) < -250 mV), because of the presence of both kinetic and thermodynamic blocks on full reduction of the FAD. A structural model of ETF (Chohan, K. K., Scrutton, N. S., and Sutcliffe, M. J. (1998) Protein Pept. Lett. 5, 231-236) suggests that the guanidinium group of Arg-237, which is located over the si face of the flavin isoalloxazine ring, plays a key role in the exceptional stabilization of the anionic semiquinone in wild-type ETF. The major effect of exchanging alphaArg-237 for Ala in M. methylotrophus ETF is to engineer a remarkable approximately 200-mV destabilization of the flavin anionic semiquinone (E'(2) = -31 +/- 2 mV, and E'(1) = -43 +/- 2 mV). In addition, reduction to the FAD dihydroquinone in alphaR237A ETF is relatively facile, indicating that the kinetic block seen in wild-type ETF is substantially removed in the alphaR237A ETF. Thus, kinetic (as well as thermodynamic) considerations are important in populating the redox forms of the protein-bound flavin. Additionally, we show that electron transfer from trimethylamine dehydrogenase to alphaR237A ETF is severely compromised, because of impaired assembly of the electron transfer complex.

TMEM237 Is Mutated in Individuals with a Joubert Syndrome Related Disorder and Expands the Role of the TMEM Family at the Ciliary Transition Zone

PubMed Central

Huang, Lijia; Szymanska, Katarzyna; Jensen, Victor L.; Janecke, Andreas R.; Innes, A. Micheil; Davis, Erica E.; Frosk, Patrick; Li, Chunmei; Willer, Jason R.; Chodirker, Bernard N.; Greenberg, Cheryl R.; McLeod, D. Ross; Bernier, Francois P.; Chudley, Albert E.; Müller, Thomas; Shboul, Mohammad; Logan, Clare V.; Loucks, Catrina M.; Beaulieu, Chandree L.; Bowie, Rachel V.; Bell, Sandra M.; Adkins, Jonathan; Zuniga, Freddi I.; Ross, Kevin D.; Wang, Jian; Ban, Matthew R.; Becker, Christian; Nürnberg, Peter; Douglas, Stuart; Craft, Cheryl M.; Akimenko, Marie-Andree; Hegele, Robert A.; Ober, Carole; Utermann, Gerd; Bolz, Hanno J.; Bulman, Dennis E.; Katsanis, Nicholas; Blacque, Oliver E.; Doherty, Dan; Parboosingh, Jillian S.; Leroux, Michel R.; Johnson, Colin A.; Boycott, Kym M.

2011-01-01

Joubert syndrome related disorders (JSRDs) have broad but variable phenotypic overlap with other ciliopathies. The molecular etiology of this overlap is unclear but probably arises from disrupting common functional module components within primary cilia. To identify additional module elements associated with JSRDs, we performed homozygosity mapping followed by next-generation sequencing (NGS) and uncovered mutations in TMEM237 (previously known as ALS2CR4). We show that loss of the mammalian TMEM237, which localizes to the ciliary transition zone (TZ), results in defective ciliogenesis and deregulation of Wnt signaling. Furthermore, disruption of Danio rerio (zebrafish) tmem237 expression produces gastrulation defects consistent with ciliary dysfunction, and Caenorhabditis elegans jbts-14 genetically interacts with nphp-4, encoding another TZ protein, to control basal body-TZ anchoring to the membrane and ciliogenesis. Both mammalian and C. elegans TMEM237/JBTS-14 require RPGRIP1L/MKS5 for proper TZ localization, and we demonstrate additional functional interactions between C. elegans JBTS-14 and MKS-2/TMEM216, MKSR-1/B9D1, and MKSR-2/B9D2. Collectively, our findings integrate TMEM237/JBTS-14 in a complex interaction network of TZ-associated proteins and reveal a growing contribution of a TZ functional module to the spectrum of ciliopathy phenotypes. PMID:22152675

48 CFR 237.7100 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Laundry and Dry Cleaning Services 237.7100 Scope. This subpart— (a) Applies to contracts for laundry and dry cleaning services within the United...

Concurrent determination of 237Np and Pu isotopes using ICP-MS: analysis of NIST environmental matrix standard reference materials 4357, 1646a, and 2702.

PubMed

Matteson, Brent S; Hanson, Susan K; Miller, Jeffrey L; Oldham, Warren J

2015-04-01

An optimized method was developed to analyze environmental soil and sediment samples for (237)Np, (239)Pu, and (240)Pu by ICP-MS using a (242)Pu isotope dilution standard. The high yield, short time frame required for analysis, and the commercial availability of the (242)Pu tracer are significant advantages of the method. Control experiments designed to assess method uncertainty, including variation in inter-element fractionation that occurs during the purification protocol, suggest that the overall precision for measurements of (237)Np is typically on the order of ± 5%. Measurements of the (237)Np concentration in a Peruvian Soil blank (NIST SRM 4355) spiked with a known concentration of (237)Np tracer confirmed the accuracy of the method, agreeing well with the expected value. The method has been used to determine neptunium and plutonium concentrations in several environmental matrix standard reference materials available from NIST: SRM 4357 (Radioactivity Standard), SRM 1646a (Estuarine Sediment) and SRM 2702 (Inorganics in Marine Sediment). Copyright © 2015 Elsevier Ltd. All rights reserved.

KSC-06pd2067

NASA Image and Video Library

2006-09-07

KENNEDY SPACE CENTER, FLA. - Storm clouds fill the sky from Launch Pad 39B, at right, west beyond the Vehicle Assembly Building. Space Shuttle Atlantis still sits on the pad after a scrub was called Aug. 27 due to a concern with fuel cell 1. Towering above the shuttle is the 80-foot lightning mast. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Ken Thornsley

sts113-s-037

NASA Image and Video Library

2002-11-23

STS113-S-037 (23 November 2002) --- Against a black night sky, the Space Shuttle Endeavour heads toward Earth orbit and a scheduled link-up with the International Space Station (ISS). Liftoff from the Kennedy Space Center's Launch Complex 39 occurred at 7:49:47 p.m. (EST), November 23, 2002. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Crewmembers onboard were astronauts James D. Wetherbee, commander; Paul S. Lockhart, pilot, along with astronauts Michael E. Lopez-Alegria and John B. Herrington, both mission specialists. Also onboard were the Expedition 6 crewmembers--astronauts Kenneth D. Bowersox and Donald R. Pettit, along with cosmonaut Nikolai M. Budarin--who went on to replace Expedition 5 aboard the Station.

sts113-s-011

NASA Image and Video Library

2002-11-23

STS113-S-011 (23 November 2002) --- Against a black night sky, the Space Shuttle Endeavour heads toward Earth orbit and a scheduled link-up with the International Space Station (ISS). Liftoff from the Kennedy Space Center's Launch Complex 39 occurred at 7:49:47 p.m. (EST), November 23, 2002. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Crewmembers onboard were astronauts James D. Wetherbee, commander; Paul S. Lockhart, pilot, along with astronauts Michael E. Lopez-Alegria and John B. Herrington, both mission specialists. Also onboard were the Expedition 6 crewmembers--astronauts Kenneth D. Bowersox and Donald R. Pettit, along with cosmonaut Nikolai M. Budarin--who went on to replace Expedition 5 aboard the Station.

sts113-s-009

NASA Image and Video Library

2002-11-23

STS113-S-009 (23 November 2002) --- Against a black night sky, the Space Shuttle Endeavour heads toward Earth orbit and a scheduled link-up with the International Space Station (ISS). Liftoff from the Kennedy Space Center's Launch Complex 39 occurred at 7:49:47 p.m. (EST), November 23, 2002. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Crewmembers onboard were astronauts James D. Wetherbee, commander; Paul S. Lockhart, pilot, along with astronauts Michael E. Lopez-Alegria and John B. Herrington, both mission specialists. Also onboard were the Expedition 6 crewmembers--astronauts Kenneth D. Bowersox and Donald R. Pettit, along with cosmonaut Nikolai M. Budarin--who went on to replace Expedition 5 aboard the Station.

STS113-S-007

NASA Image and Video Library

2002-11-23

STS113-S-007 (23 November 2002) --- Against a black night sky, the Space Shuttle Endeavour heads toward Earth orbit and a scheduled link-up with the International Space Station (ISS). Liftoff from the Kennedy Space Center's Launch Complex 39 occurred at 7:49:47 p.m. (EST), November 23, 2002. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Crewmembers onboard were astronauts James D. Wetherbee, commander; Paul S. Lockhart, pilot, along with astronauts Michael E. Lopez-Alegria and John B. Herrington, both mission specialists. Also onboard were the Expedition 6 crewmembers--astronauts Kenneth D. Bowersox and Donald R. Pettit, along with cosmonaut Nikolai M. Budarin--who went on to replace Expedition 5 aboard the Station.

STS113-S-005

NASA Image and Video Library

2002-11-23

STS113-S-005 (23 November 2002) --- Against a black night sky, the Space Shuttle Endeavour heads toward Earth orbit and a scheduled link-up with the International Space Station (ISS). Liftoff from the Kennedy Space Center's Launch Complex 39 occurred at 7:49:47 p.m. (EST), November 23, 2002. The launch is the 19th for Endeavour, and the 112th flight in the Shuttle program. Mission STS-113 is the 16th assembly flight to the International Space Station, carrying another structure for the Station, the P1 integrated truss. Crewmembers onboard were astronauts James D. Wetherbee, commander; Paul S. Lockhart, pilot, along with astronauts Michael E. Lopez-Alegria and John B. Herrington, both mission specialists. Also onboard were the Expedition 6 crewmembers--astronauts Kenneth D. Bowersox and Donald R. Pettit, along with cosmonaut Nikolai M. Budarin--who went on to replace Expedition 5 aboard the Station.

NBL experimental photographic support: STS-111-UF2

NASA Image and Video Library

2008-12-05

JSC2001-02996 (December 2001) --- Astronauts Philippe Perrin and Franklin R. Chang-Diaz practice procedures to be used during space walks scheduled to perform work on the International Space Station (ISS). The two STS-111 mission specialists, wearing training versions of the Extravehicular Mobility Unit (EMU) space suit, make use of the Neutral Buoyancy Laboratory (NBL) giant pool to rehearse their assigned chores. While the Space Shuttle Endeavour is docked to the orbital outpost, two space walks are scheduled to hook up the mobile base system, the second part of the mobile platform for the station’s Canadarm2 robotic arm and other assembly tasks. Perrin represents CNES, the French Space Agency. STS-111 will be the 14th shuttle mission to visit the orbital outpost.

NBL experimental photographic support: STS-111-UF2

NASA Image and Video Library

2008-12-05

JSC2001-02995 (December 2001) --- Astronauts Philippe Perrin and Franklin R. Chang-Diaz practice procedures to be used during space walks scheduled to perform work on the International Space Station (ISS). The two STS-111 mission specialists, wearing training versions of the Extravehicular Mobility Unit (EMU) space suit, make use of the Neutral Buoyancy Laboratory (NBL) giant pool to rehearse their assigned chores. While the Space Shuttle Endeavour is docked to the orbital outpost, two space walks are scheduled to hook up the mobile base system, the second part of the mobile platform for the station’s Canadarm2 robotic arm and other assembly tasks. Perrin represents CNES, the French Space Agency. STS-111 will be the 14th shuttle mission to visit the orbital outpost.

KSC-03pd0117

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. - A crowd by the countdown clock watches as Space Shuttle Columbia roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

KSC-03pd0116

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. - Seconds after launch, Space Shuttle Columbia appears as a flaming tip of the smoke column it trails. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

KSC-03pd0119

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. -- Seconds after launch, Space Shuttle Columbia appears as a flaming tip of the smoke column it trails. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

KSC-03pd0115

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. -- Trailing a twisting column of smoke, Space Shuttle Columbia hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

KSC-03pd0114

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. -- Space Shuttle Columbia hurtles through a perfect blue Florida sky following a flawless and uneventful countdown. Liftoff of Columbia on mission STS-107 occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program

Final Report 10th Conference on the Intersections of Particle and Nuclear Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marshak, Marvin L.

2013-11-03

The 10th Conference on the Intersections of Particle and Nuclear Physics was held in LaJolla, California on May 26 to May 31, 2009. The Conference Proceedings are published by the American Institute of Physics in Volume 1182 of the AIP Conference Proceedings (ISBN: 978-0-7354-0723-7). The Proceedings include papers from each of the Conference Presenters and a detailed schedule of talks at the Conference. The Table of Contents of the Conference Proceedings is available at http://scitation.aip.org/content/aip/proceeding/aipcp/1182. Support by the U.S. Department of Energy and by DOE Laboratories was essential to the success of the Conference.

KSC-2009-2017

NASA Image and Video Library

2009-03-10

CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Richard Arnold gets help from a suit technician in the final fitting of his launch and entry suit. Arnold will be making his first shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

KSC-2009-2018

NASA Image and Video Library

2009-03-10

CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist John Phillips has a final fitting of his launch and entry suit and the helmet. Phillips is making his third shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

KSC-2009-2013

NASA Image and Video Library

2009-03-10

CAPE CANAVERAL, Fla. – – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Joseph Acaba has a final fitting of his launch and entry suit. Acaba is making his first shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

KSC-2009-2012

NASA Image and Video Library

2009-03-10

CAPE CANAVERAL, Fla. – In the Operations and Checkout Building at NASA's Kennedy Space Center in Florida, STS-119 Mission Specialist Richard Arnold signals he is ready for launch during the final fitting of his launch and entry suit. Arnold is making his first shuttle flight. The 14-day mission is the 28th to the International Space Station and the 125th space shuttle flight. Discovery will deliver the final pair of power-generating solar array wings and the S6 truss segment. Installation of S6 will signal the station's readiness to house a six-member crew for conducting increased science. Liftoff of Discovery is scheduled for 9:20 p.m. EDT on March 11. Photo credit: NASA/Kim Shiflett

KSC-07pd1420

NASA Image and Video Library

2007-06-08

KENNEDY SPACE CENTER, FLA. -- STS-117 Mission Specialist John "Danny" Olivas signals go for launch as he completes suitup by donning his helmet. The launch of Space Shuttle Atlantis is scheduled for 7:38 p.m. EDT from Launch Pad 39A. The shuttle is delivering a new segment to the starboard side of the International Space Station's backbone, known as the truss. Three spacewalks are planned to install the S3/S4 truss segment, deploy a set of solar arrays and prepare them for operation. STS-117 is the 118th space shuttle flight, the 21st flight to the station, the 28th flight for Atlantis and the first of four flights planned for 2007. Photo credit: NASA/Kim Shiflett

Numerical Solution of Laminar and Turbulent Boundary Layer Equations Including Transition, and Experimenmtal Study of a Flat Plate with a Blunt Fin at Incidence.

DTIC Science & Technology

1986-03-01

93 3.6.5.4 Data Acquisition- Electrical Analog. . 95 3.6.6 Co-axial Thermocouple Gages ...... 97 3.6.6.1 Theory .................... 101 3.6.6.2...Preparation of Liquid Crystal Model . . . 233 Appendix G: Digital Image Processing . ........ 235 Appendix H: Electrical Analog Circuits ....... . 237...m. 232 H.la Thermal Circuit ..... ................. . 237 H.Ib Electrical Circuit ..... ............... 237 H.2 Electrical Analog Using Equal Sections

48 CFR 237.7301 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... good standing in a curriculum designed to lead to the granting of a recognized degree, during the term... Development Laboratories 237.7301 Definitions. As used in this subpart— (a) Institution of higher learning...

Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides.

PubMed

Garcia, Alexis; Adedoyin, Gloria; Heitman, Joseph; Lee, Soo Chan

2017-07-05

Mucor circinelloides is a human pathogen, biofuel producer, and model system that belongs to a basal fungal lineage; however, the genetics of this fungus are limited. In contrast to ascomycetes and basidiomycetes, basal fungal lineages have been understudied. This may be caused by a lack of attention given to these fungi, as well as limited tools for genetic analysis. Nonetheless, the importance of these fungi as pathogens and model systems has increased. M. circinelloides is one of a few genetically tractable organisms in the basal fungi, but it is far from a robust genetic system when compared to model fungi in the subkingdom Dikarya. One problem is the organism is resistant to drugs utilized to select for dominant markers in other fungal transformation systems. Thus, we developed a blaster recyclable marker system by using the pyrG gene (encoding an orotidine-5'-phosphate decarboxylase, ortholog of URA3 in Saccharomyces cerevisiae ). A 237-bp fragment downstream of the pyrG gene was tandemly incorporated into the upstream region of the gene, resulting in construction of a pyrG-dpl237 marker. To test the functionality of the pyrG-dpl237 marker, we disrupted the carRP gene that is involved in carotenoid synthesis in pyrG - mutant background. The resulting carRP :: pyrG-dpl237 mutants exhibit a white colony phenotype due to lack of carotene, whereas wild type displays yellowish colonies. The pyrG marker was then successfully excised, generating carRP-dpl237 on 5-FOA medium. The mutants became auxotrophic and required uridine for growth. We then disrupted the calcineurin B regulatory subunit cnbR gene in the carRP :: dpl237 strain, generating mutants with the alleles carRP :: dpl237 and cnbR :: pyrG These results demonstrate that the recyclable marker system is fully functional, and therefore the pyrG-dpl237 marker can be used for sequential gene deletions in M. circinelloides . Copyright © 2017 Garcia et al.

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle.

PubMed

Frøsig, Christian; Pehmøller, Christian; Birk, Jesper B; Richter, Erik A; Wojtaszewski, Jørgen F P

2010-11-15

TBC1D1 is a Rab-GTPase activating protein involved in regulation of GLUT4 translocation in skeletal muscle. We here evaluated exercise-induced regulation of TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle. In separate experiments healthy men performed all-out cycle exercise lasting either 30 s, 2  min or 20  min. After all exercise protocols, TBC1D1 Ser237 phosphorylation increased (∼70-230%, P < 0.005), with the greatest response observed after 20  min of cycling. Interestingly, capacity of TBC1D1 to bind 14-3-3 protein showed a similar pattern of regulation, increasing 60-250% (P < 0.001). Furthermore, recombinant 5AMP-activated protein kinase (AMPK) induced both Ser237 phosphorylation and 14-3-3 binding properties on human TBC1D1 when evaluated in vitro. To further characterize the role of AMPK as an upstream kinase regulating TBC1D1, extensor digitorum longus muscle (EDL) from whole body α1 or α2 AMPK knock-out and wild-type mice were stimulated to contract in vitro. In wild-type and α1 knock-out mice, contractions resulted in a similar ∼100% increase (P < 0.001) in Ser237 phosphorylation. Interestingly, muscle of α2 knock-out mice were characterized by reduced protein content of TBC1D1 (∼50%, P < 0.001) as well as in basal and contraction-stimulated (∼60%, P < 0.001) Ser237 phosphorylation, even after correction for the reduced TBC1D1 protein content. This study shows that TBC1D1 is Ser237 phosphorylated and 14-3-3 protein binding capacity is increased in response to exercise in human skeletal muscle. Furthermore, we show that the catalytic α2 AMPK subunit is the main (but probably not the only) donor of AMPK activity regulating TBC1D1 Ser237 phosphorylation in mouse EDL muscle.

Teaming for Leadership. Summary Report of the Annual Southeastern Regional Media Leadership Council (17th, Jacksonville, Florida, February 28-March 2, 1986).

ERIC Educational Resources Information Center

Southeastern Regional Media Leadership Council.

This summary report of the 1986 annual meeting of the Southeastern Regional Media Leadership Council (SRMLC) includes: letters of welcome from Director Bo Bostick and Herb A. Sang, Superintendent of Schools, Duval County Public Schools; a listing of the host state committees; a conference schedule; acknowledgements; the minutes of the 1985…

STS-95 Discovery rolls over to the VAB

NASA Technical Reports Server (NTRS)

1998-01-01

In the Vehicle Assembly Building, workers prepare the orbiter Discovery for vertical lift before mating it with the external tank. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left wing and both sides of the fuselage. Discovery (OV-103) is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

STS-95 Discovery rolls over to the VAB

NASA Technical Reports Server (NTRS)

1998-01-01

KSC employees accompany the orbiter Discovery on its rollover from the Orbiter Processing Facility Bay 2 to the Vehicle Assembly Building. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left wing and both sides of the fuselage. Discovery (OV-103) is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

STS-95 Discovery rolls over to the VAB

NASA Technical Reports Server (NTRS)

1998-01-01

Morning shadows frame the orbiter Discovery on its rollover from the Orbiter Processing Facility Bay 2 to the Vehicle Assembly Building. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left wing and both sides of the fuselage. Discovery (OV-103) is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

U.S. Coast Guard Fleet Mix Planning: A Decision Support System Prototype

DTIC Science & Technology

1991-03-01

91-16785 Al ’ 1 1 1 Unclassified SECURITY CLASSIFICATION OF ThIS PAGE REPORT DOCUMENTATION PAGE I L REPORTSECURITY CLASSIFICATION lb. RESTRICTIVE...MARKINGS Unclassified 2a. SECURITY CLASSIFICATION AUTHORITY 3. DISTRIBUTION/ AVAILABITY OF REPORT Approved for public release; distribution is inlimited...2b. DECIASSIFICATION/DOWNGRADING SCHEDULE 4. PERFORMING ORGANIZATION REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) 6a. NAME OF

Aircraft Scheduled Structural Maintenance Programs: Current Philosophies and Methods in the United States and their Applicability to the Royal Australian Air Force

DTIC Science & Technology

1988-09-01

maintenance programs. They use "a dedicated age exploration technique and actuarial analyses (31:847)" to Justify any changes to programs. RAAF. The...A066593). 8. Coffin, M.D. and C.F. Tiffany. "New Air Force Requirements for Structural Safety, Durability and Life Management," AIAA/ ASME /SAE 16th

76 FR 53829 - Safety Zone; ESI Ironman 70.3 Augusta Triathlon, Savannah River, Augusta, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... participants, participant vessels, spectators, and the general public during the 1.1 mile swim portion of the... scheduled to take place in Augusta, Georgia. This event includes a 1.1 mile swim that will take place on the waters of the Savannah River. The swim starts at the 6th Street Railroad Bridge and finishes at Mile Post...

Review of Related Literature and Research: History of Merit Pay, Differentiated Staffing, and Incentive Pay Programs.

ERIC Educational Resources Information Center

Guernsey, Marsha A.

This paper reviews selected literature pertaining to merit pay, differentiated staffing, and incentive pay programs. The first section reviews the history of these alternatives to the single salary schedule, beginning with an account of two experimental merit pay plans in the early 20th century. During the 1920s, merit pay plans gave way to the…

46 CFR 108.237 - Fuel storage facilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.237 Fuel storage facilities. (a) Helicopter fuel storage tanks must be installed as far as practicable from— (1) The landing area; and (2...

7 CFR 58.237 - Condensed surge supply.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., GENERAL SPECIFICATIONS FOR APPROVED PLANTS AND STANDARDS FOR GRADES OF DAIRY PRODUCTS 1 General... Procedures § 58.237 Condensed surge supply. Surge tanks or balance tanks if used between the evaporators and...

32 CFR 237a.3 - Objective and policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) MISCELLANEOUS PUBLIC AFFAIRS LIAISON WITH INDUSTRY § 237a.3 Objective and policy. (a) It is important that... community, consistent with national security, and (2) cooperation with industry in public relations...

KSC-06pd2052

NASA Image and Video Library

2006-09-06

KENNEDY SPACE CENTER, FLA. - The morning sky lightens behind Space Shuttle Atlantis while lights on the fixed service structure (FSS) still illuminate the orbiter on Launch Pad 39B. Atlantis was originally scheduled to launch at 12:29 p.m. EDT on this date, but a 24-hour scrub was called by mission managers due to a concern with Fuel Cell 1. Seen poised above the orange external tank is the vent hood (known as the "beanie cap") at the end of the gaseous oxygen vent arm. Vapors are created as the liquid oxygen in the external tank boil off. The hood vents the gaseous oxygen vapors away from the space shuttle vehicle. Extending from the FSS to Atlantis is the orbiter access arm with the White Room at the end. The White Room provides entry into the orbiter through the hatch. At right is the 300,000-gallon water tank that releases its contents onto the mobile launcher platform during liftoff to aid sound suppression. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Troy Cryder

KSC-06pd2051

NASA Image and Video Library

2006-09-06

KENNEDY SPACE CENTER, FLA. - The morning sky lightens behind Space Shuttle Atlantis while lights on the fixed service structure (FSS) still illuminate the orbiter on Launch Pad 39B. Atlantis was originally scheduled to launch at 12:29 p.m. EDT on this date, but a 24-hour scrub was called by mission managers due to a concern with Fuel Cell 1. Seen poised above the orange external tank is the vent hood (known as the "beanie cap") at the end of the gaseous oxygen vent arm. Vapors are created as the liquid oxygen in the external tank boil off. The hood vents the gaseous oxygen vapors away from the space shuttle vehicle. Extending from the FSS to Atlantis is the orbiter access arm with the White Room at the end. The White Room provides entry into the orbiter through the hatch. At right is the 300,000-gallon water tank that releases its contents onto the mobile launcher platform during liftoff to aid sound suppression. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the International Space Station. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Troy Cryder

In vitro stimulatory effect of N-acetyl tryptophan-glucopyranoside against gamma radiation induced immunosuppression.

PubMed

Malhotra, Poonam; Singh, Darshana; Kumar, Raj

2018-03-01

Radiation-induced manifestations like free radical burst, oxidative damage and apoptosis leading to cell death. In present study, N-acetyl tryptophan glucopyranoside (NATG) was assessed for its immune-radioprotective activities using J774A.1 cells. Clonogenic cell survival, cell cycle progression and cytokines i.e. IFN-γ, TNF-α, IL-2, IL-10, IL-12, IL-13 and IL-17A expression were evaluated in irradiated and NATG pretreated cells using clonogenic formation ability, flow cytometry and ELISA assay. Results indicated that 0.25μg/ml NATG exhibited maximum radioprotection against gamma-radiation (2Gy) without intervening in cell cycle progression. NATG pretreated (-2 h) plus irradiated cells showed significant elevation in IFN-γ (∼38.2%), IL-17A (∼53.7%) and IL-12 (∼58.8%) expression as compared to only irradiated cells. Conversely, significant decrease in TNF-α (∼21.6%), IL-10 (∼31.2%), IL-2 (∼23.7%) and IL-13 expression (∼17.8%) were observed in NATG pretreated plus irradiated cells as compared to irradiated cells. Conclusively, NATG pretreatment to irradiated J774A.1 cells, stimulate Th 1 while diminish Th 2 cytokines that contributes to radioprotection. © 2017 Wiley Periodicals, Inc.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eppich, Gary R.; Williams, Ross W.; Gaffney, Amy M.

Here, age dating of nuclear material can provide insight into source and suspected use in nuclear forensic investigations. We report here a method for the determination of the date of most recent chemical purification for uranium materials using the 235U- 231Pa chronometer. Protactinium is separated from uranium and neptunium matrices using anion exchange resin, followed by sorption of Pa to an SiO 2 medium. The concentration of 231Pa is measured by isotope dilution mass spectrometry using 233Pa spikes prepared from an aliquot of 237Np and calibrated in-house using the rock standard Table Mountain Latite and the uranium isotopic standard U100.more » Combined uncertainties of age dates using this method are 1.5 to 3.5 %, an improvement over alpha spectrometry measurement methods. Model ages of five uranium standard reference materials are presented; all standards have concordant 235U- 231Pa and 234U- 230Th model ages.« less

Study of fission using multi-nucleon transfer reactions

NASA Astrophysics Data System (ADS)

Nishio, Katsuhisa; Hirose, Kentaro; Mark, Vermeulen; Makii, Hiroyuki; Orlandi, Riccardo; Tsukada, Kazuaki; Asai, Masato; Toyoshima, Atsushi; Sato, Tetsuya K.; Nagame, Yuichiro; Chiba, Satoshi; Aritomo, Yoshihiro; Tanaka, Shouya; Ohtsuki, Tsutomu; Tsekhanovich, Igor; Petrache, Costel M.; Andreyev, Andrei

2017-11-01

It is shown that multi-nucleon transfer reaction is a powerful tool to study fission of exotic neutronrich actinide nuclei, which cannot be accessed by particle-capture or heavy-ion fusion reactions. In this work, multi-nucleon transfer channels of the reactions of 18O+232Th, 18O+238U, 18O+248Cm, and 18O+237Np were used to measure fission-fragment mass distribution for each transfer channel. Predominantly asymmetric fission is observed at low excitation energies for all the studied cases, with an increase of the symmetric fission towards high excitation energies. Experimental data are compared with predictions of the fluctuation-dissipation model, where effects of multi-chance fission (neutron evaporation prior to fission) was introduced. It is shown that mass-asymmetric structure remaining at high excitation energies originates from low-excited and less neutronrich excited nuclei due to higher-order chance fissions.

48 CFR 2437.110 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... insert the clause at 2452.237-72, Coordination of Data Collection Activities, in solicitations and...) The Contracting Officer shall insert the clause at 48 CFR 2452.237-73, Conduct of Work and Technical...

Zircon U-Pb dating of eclogite from the Qiangtang terrane, north-central Tibet: a case of metamorphic zircon with magmatic geochemical features

NASA Astrophysics Data System (ADS)

Zhai, Qing-guo; Jahn, Bor-ming; Li, Xian-hua; Zhang, Ru-yuan; Li, Qiu-li; Yang, Ya-nan; Wang, Jun; Liu, Tong; Hu, Pei-yuan; Tang, Suo-han

2017-06-01

Zircon is probably the most important mineral used in the dating formation of high-pressure (HP) and ultrahigh-pressure (UHP) metamorphic rocks. The origin of zircon, i.e., magmatic or metamorphic, is commonly assessed by its external morphology, internal structure, mineral inclusions, Th/U ratios and trace element composition. In this study, we present an unusual case of metamorphic zircon from the Qiangtang eclogite, north-central Tibet. The zircon grains contain numerous eclogite-facies mineral inclusions, including omphacite, phengite, garnet and rutile; hence, they are clearly of metamorphic origin. However, they display features similar to common magmatic zircon, including euhedral crystal habit, high Th/U ratios and enriched heavy rare earth elements pattern. We suggest that these zircon grains formed from a different reservoir from that for garnet where no trace elements was present and trace element equilibrium between zircon and garnet was achieved. U-Pb dating of zircon gave an age of 232-237 Ma for the eclogite, and that of rutile yielded a slightly younger age of ca. 217 Ma. These ages are consistent with the reported Lu-Hf mineral isochron and phengite Ar-Ar ages. The zircon U-Pb and mineral Lu-Hf isochron ages are interpreted as the time of the peak eclogite-facies metamorphism, whereas the rutile U-Pb and phengite Ar-Ar ages represent the time of exhumation to the middle crust. Thus, the distinction between metamorphic and magmatic zircons cannot be made using only Th/U ratios and heavy REE compositions for HP-UHP metamorphic rocks of oceanic derivation.

Rapid determination of 237Np in soil samples by multi-collector inductively-coupled plasma mass spectrometry and gamma spectrometry.

PubMed

Yi, Xiaowei; Shi, Yanmei; Xu, Jiang; He, Xiaobing; Zhang, Haitao; Lin, Jianfeng

A radiochemical procedure is developed for the determination of 237 Np in soil with multi-collector inductively-coupled plasma mass spectrometry (MC-ICP-MS) and gamma-spectrometry. 239 Np (milked from 243 Am) was used as an isotopic tracer for chemical yield determination. The neptunium in the soil is separated by thenoyl-trifluoracetone extraction from 1 M HNO 3 solution after reducing Np to Np(IV) with ferrous sulfamate, and then purified with Dowex 1 × 2 anion exchange resin. 239 Np in the resulting solution is measured with gamma-spectrometry for chemical yield determination while the 237 Np is measured with MC-ICP-MS. Measurement results for soil samples are presented together with those for two reference samples. By comparing the determined value with the reference value of the 237 Np activity concentration, the feasibility of the procedure was validated.

KSC-146fr3

NASA Image and Video Library

1998-02-13

Technicians observe the alpha-magnetic spectrometer (AMS-1) after it was removed from its protective shipping case in KSC’s Multi Payload Processing Facility (MPPF). The STS-91 payload arrived at KSC in January and is scheduled to be flown on the 9th and final Mir docking mission, scheduled for launch in May. The objectives of the AMS-1 investigation are to search for anti-matter and dark matter in space and to study astrophysics. The STS-91 flight crew includes Commander Charles Precourt; Pilot Dominic Gorie; and Mission Specialists Wendy B. Lawrence; Franklin Chang-Diaz, Ph.D.; Janet Kavandi, Ph.D.; and Valery Ryumin, with the Russian Space Agency. After docking with the Russian Space Station Mir, Mission Specialist Andrew Thomas, Ph.D., will join the STS-91 crew and return to Earth aboard Discovery

KSC-147fr11

NASA Image and Video Library

1998-02-13

A technician observes the alpha-magnetic spectrometer (AMS-1) after it was removed from its protective shipping case in KSC’s Multi Payload Processing Facility (MPPF). The STS-91 payload arrived at KSC in January and is scheduled to be flown on the 9th and final Mir docking mission, scheduled for launch in May. The objectives of the AMS-1 investigation are to search for anti-matter and dark matter in space and to study astrophysics. The STS-91 flight crew includes Commander Charles Precourt; Pilot Dominic Gorie; and Mission Specialists Wendy B. Lawrence; Franklin Chang-Diaz, Ph.D.; Janet Kavandi, Ph.D.; and Valery Ryumin, with the Russian Space Agency. After docking with the Russian Space Station Mir, Mission Specialist Andrew Thomas, Ph.D., will join the STS-91 crew and return to Earth aboard Discovery

KSC-143fr8

NASA Image and Video Library

1998-02-13

Technicians assist in moving the alpha-magnetic spectrometer (AMS-1) from its protective shipping case in KSC’s Multi Payload Processing Facility (MPPF). The STS-91 payload arrived at KSC in January and is scheduled to be flown on the 9th and final Mir docking mission, scheduled for launch in May. The objectives of the AMS-1 investigation are to search for anti-matter and dark matter in space and to study astrophysics. The STS-91 flight crew includes Commander Charles Precourt; Pilot Dominic Gorie; and Mission Specialists Wendy B. Lawrence; Franklin Chang-Diaz, Ph.D.; Janet Kavandi, Ph.D.; and Valery Ryumin, with the Russian Space Agency. After docking with the Russian Space Station Mir, Mission Specialist Andrew Thomas, Ph.D., will join the STS-91 crew and return to Earth aboard Discovery

The current status of medical marijuana in the United States.

PubMed

McKenna, Gerald J

2014-04-01

Medical marijuana is currently a controversial issue in medicine. There are strong pro and con opinions but relatively little scientific data on which to base medical decisions. The unfortunate scheduling of marijuana in class I has limited research and only serves to fuel the controversy. This article will review the history of laws to regulate drugs in the United States in the 20th century to provide context for the current status of medical marijuana. It will include the rationale for opposing medical marijuana laws and the problem of the Schedule I inclusion of marijuana as well as other drugs. It will examine the problems associated with smoking raw marijuana and review other routes of administration. Finally, it examines the inadvisability of medicine's promotion of smoked marijuana.

Department of Defense Status of Year 2000 Efforts. 11th Quarterly Progress Report

DTIC Science & Technology

1999-11-15

Duplicate systems corrected when all Intelligence mission critical systems were folded into the unclassified OSD database to allow for complete tracking in...one database. - 2 Two Intelligence Systems that were scheduled to be terminated or replaced that have been reclassified to non-mission...National Communication System participated in the Federal Sector Group meetings and assessed our role in the functional testing. Industry conducted

Unleash the Power! Knowledge - Technology - Diversity: Papers Presented at the Third International Forum on Research in School Librarianship, Annual Conference of the International Association of School Librarianship (IASL) (28th, Birmingham, Alabama, November 10-14, 1999).

ERIC Educational Resources Information Center

Lighthall, Lynne, Ed.; Howe, Eleanor, Ed.

Papers presented at this forum were grouped under the following four broad themes: "Unleash the Power!,""Powerful Roles,""Powerful Partnerships," and "Powerful Technologies." Also included is the paper that won the Takeshi Murofushi Research Award, "Implementing Flexible Scheduling in Elementary…

STS-95 Discovery rolls over to the VAB

NASA Technical Reports Server (NTRS)

1998-01-01

Rollover of the orbiter Discovery from the Orbiter Processing Facility Bay 2 to the Vehicle Assembly Building draws the attention of KSC employees. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left wing and both sides of the fuselage. Discovery (OV-103) is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

STS-95 Discovery rolls over to the VAB

NASA Technical Reports Server (NTRS)

1998-01-01

The orbiter Discovery is moved from the Orbiter Processing Facility Bay 2 to the Vehicle Assembly Building, drawing the attention of KSC employees. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left wing and both sides of the fuselage. Discovery (OV-103) is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

KSC-2011-2976

NASA Image and Video Library

2011-04-07

CAPE CANAVERAL, Fla. - At the Cape Canaveral Air Force Station forecast facility in Florida, a member of the weather team demonstrates the effectiveness of the new weather radar display recently installed. The facility is operated by the U.S. Air Force 45th Weather Squadron and will generate a launch weather forecast for the scheduled July 8 lift off of space shuttle Atlantis on the STS-135 mission. Photo credit: NASA/Jack Pfaller

KSC-2011-2975

NASA Image and Video Library

2011-04-07

CAPE CANAVERAL, Fla. - At the Cape Canaveral Air Force Station forecast facility in Florida, a member of the weather team demonstrates the effectiveness of the new weather radar display recently installed. The facility is operated by the U.S. Air Force 45th Weather Squadron and will generate a launch weather forecast for the scheduled July 8 lift off of space shuttle Atlantis on the STS-135 mission. Photo credit: NASA/Jack Pfaller

Salaries and Wages Paid Professional and Support Personnel in Public Schools, 2009-2010. A Reference Tool for School Administrators

ERIC Educational Resources Information Center

Protheroe, Nancy; Licciardi, Christopher M.; Cooke, Willa D.

2010-01-01

This report presents salary and wage data collected as part of the 37th edition of the "ERS National Survey of Salaries and Wages in Public Schools, 2009-2010." The survey, conducted in fall 2008, collected data on salaries scheduled and salaries paid for 23 selected professional positions and 10 selected support positions in public school systems…

The United States, the South Atlantic, and Antarctic: Interests and Challenges

DTIC Science & Technology

1990-06-01

3) Probability of attack from the South was greatest in 1962. Not since the Navy’s 4th Fleet was based in northern Brazil during the Second World...Brazil’s attack aircraft are not carrier-borne. Brazil possesses a well-developed military armaments industry like Argentina, but its export sector far...release; ,. DECLASSIFICATIONJDOWNGRADING SCHEDULE distribution is unlimited PERFORMING ORGANIZATION REPORT NUMBER( S ) 5. MONITORING ORGANIZATION REPORT

An Overview of MSHN: The Management System for Heterogeneous Networks

DTIC Science & Technology

1999-04-01

An Overview of MSHN: The Management System for Heterogeneous Networks Debra A. Hensgen†, Taylor Kidd†, David St. John§, Matthew C . Schnaidt†, Howard...ABSTRACT UU 18. NUMBER OF PAGES 15 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c . THIS PAGE...Alhusaini, V. K. Prasanna, and C . S. Raghavendra, “A unified resource scheduling framework for heterogeneous computing environments,” Proc. 8th IEEE

East Europe Report Economic and Industrial Affairs No. 2390

DTIC Science & Technology

1983-04-22

Discussed (B-. GIilan, et al .; BORBA , 7 Mar 83) ......................... 89 -b - ALBANIA DEVELOPMENTS IN COLOR TELEVISION BROADCASTING Tirana BASHKIMI...experiment- al work was carried on with limited and irregular schedules. The beginning of regular programming coincided with the 6th party congress in...upheav- als . But the practice of permanent revolution has set back for a long time even such a huge country, with a great cultural heritage, enormous

KSC-2011-1593

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. - In the Operations and Checkout Building (O&C) at NASA's Kennedy Space Center in Florida, the astronauts of space shuttle Discovery's STS-133 crew put on their launch-and-entry suits and check the fit of their helmets and gloves before heading to the Astrovan for the ride to Launch Pad 39A. Mission Specialist Steve Bowen, seen here, is making his third spaceflight. The last time he suited up for flight was in May 2010 for the STS-132 mission. Bowen replaces astronaut Tim Kopra as Mission Specialist 2, because Kopra was injured in a recent bicycle accident that prevented him from lifting off during this launch window. Scheduled to lift off Feb. 24 at 4:50 p.m. EST, Discovery and its crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

KSC-2011-1594

NASA Image and Video Library

2011-02-24

CAPE CANAVERAL, Fla. - In the Operations and Checkout Building (O&C) at NASA's Kennedy Space Center in Florida, the astronauts of space shuttle Discovery's STS-133 crew put on their launch-and-entry suits and check the fit of their helmets and gloves before heading to the Astrovan for the ride to Launch Pad 39A. Mission Specialist Steve Bowen, seen here, is making his third spaceflight. The last time he suited up for flight was in May 2010 for the STS-132 mission. Bowen replaces astronaut Tim Kopra as Mission Specialist 2, because Kopra was injured in a recent bicycle accident that prevented him from lifting off during this launch window. Scheduled to lift off Feb. 24 at 4:50 p.m. EST, Discovery and its crew will deliver the Permanent Multipurpose Module, packed with supplies and critical spare parts, as well as Robonaut 2, the dexterous humanoid astronaut helper, to the International Space Station. Discovery, which will fly its 39th mission, is scheduled to be retired following STS-133. This will be the 133rd Space Shuttle Program mission and the 35th shuttle voyage to the space station. For more information on the STS-133 mission, visit www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts133/. Photo credit: NASA/Jim Grossmann

48 CFR 237.7200 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... agreements, i.e., payment by the Government of partial tuition under the off-duty educational program. (b) As... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Educational Service Agreements 237.7200 Scope. (a) This subpart prescribes acquisition procedures for educational services from schools...

48 CFR 237.7200 - Scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... agreements, i.e., payment by the Government of partial tuition under the off-duty educational program. (b) As... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Educational Service Agreements 237.7200 Scope. (a) This subpart prescribes acquisition procedures for educational services from schools...