Mini-Journal Inquiry Laboratory: A Case Study in a General Chemistry Kinetics Experiment

ERIC Educational Resources Information Center

Zhao, Ningfeng; Wardeska, Jeffrey G.

2011-01-01

The mini-journal curriculum for undergraduate science laboratories mirrors the format of scientific literature and helps students improve their learning through direct scientific practices. The lab embodies the essential features of scientific inquiry and replaces the traditional "cookbook" lab to engage students in active learning. A case study…

Microbes in Mascara: Hypothesis-Driven Research in a Nonmajor Biology Lab †

PubMed Central

Burleson, Kathryn M.; Martinez-Vaz, Betsy M.

2011-01-01

In this laboratory exercise, students were taught concepts of microbiology and scientific process through an everyday activity — cosmetic use. The students’ goals for the lab were to develop a hypothesis regarding microbial contamination in cosmetics, learn techniques to culture and differentiate microorganisms from cosmetics, and propose best practices in cosmetics use based on their findings. Prior to the lab, students took a pretest to assess their knowledge of scientific hypotheses, microbiology, and cosmetic safety. In the first week, students were introduced to microbiological concepts and methodologies, and cosmetic terminology and safety. Students completed a hypothesis-writing exercise before formulating and testing their own hypotheses regarding cosmetic contamination. Students provided a cosmetic of their own and, in consultation with their lab group, chose one product for testing. Samples were serially diluted and plated on a variety of selective media. In the second week, students analyzed their plates to determine the presence and diversity of microbes and if their hypotheses were supported. Students completed a worksheet of their results and were given a posttest to assess their knowledge. Average test scores improved from 5.2 (pretest) to 7.8 (posttest), with p-values < 0.0001. Seventy-nine percent (79%) of students correctly identified hypotheses that were not falsifiable or lacked variables, and 89% of students improved their scores on questions concerning safe cosmetic use. Ninety-one percent (91%) of students demonstrated increased knowledge of microbial concepts and methods. Based on our results, this lab is an easy, yet effective, way to enhance knowledge of scientific concepts for nonmajors, while maintaining relevance to everyday life. PMID:23653761

How Do You Like Your Science, Wet or Dry? How Two Lab Experiences Influence Student Understanding of Science Concepts and Perceptions of Authentic Scientific Practice

ERIC Educational Resources Information Center

Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W.; Levias, Sheldon

2017-01-01

This study examines how two kinds of authentic research experiences related to smoking behavior--genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)--influence students' perceptions and understanding of scientific research and related science concepts. The study used pre and…

Perceptions of Prospective Biology Teachers on Scientific Argumentation in Microbiology Inquiry Lab Activities

NASA Astrophysics Data System (ADS)

Roviati, E.; Widodo, A.; Purwianingsih, W.; Riandi, R.

2017-09-01

Inquiry laboratory activity and scientific argumentation in science education should be promoted and explicitly experienced by prospective biology teacher students in classes, including in microbiology courses. The goal of this study is to get information about perceptions of prospective biology teachers on scientific argumentation in microbiology inquiry lab activities. This study reported the result of a survey research to prospective biology teachers about how their perception about microbiology lab classes and their perception about inquiry and argumentation in microbiology lab activities should be. The participants of this study were 100 students of biology education department from an institute in Cirebon, West Java taking microbiology lecture during the fifth semester. The data were collected using questionnaire to explore the perceptions and knowledge of prospective biology teachers about microbiology, inquiry lab activities and argumentation. The result showed that students thought that the difficulties of microbiology as a subject were the lack of references and the way lecturer teaching. The students’ perception was that argumentation and inquiry should be implemented in microbiology courses and lab activities. Based on the data from questionnaire, It showed that prospective biology teacher students had very little knowledge about scientific argumentation and its implementation in science education. When the participants made arguments based on the problems given, they showed low quality of arguments.

Mentos and Scientific Method: A Sweet Combination

ERIC Educational Resources Information Center

Eichler, Jack F.; Patrick, Heather; Harmon, Brenda; Coonce, Janet

2007-01-01

Several active-learning techniques and inquiry-driven laboratory exercises were incorporated in labs to determine the effects of these methodologies on the fundamental skills of the students. The practice has been found extremely useful for developing the learning abilities of the students.

The History of Science and Technology at Bell Labs

NASA Astrophysics Data System (ADS)

Bishop, David

2008-03-01

Over the last 80 years, Bell Labs has been one of the most scientifically and technologically productive research labs in the world. Inventions such as the transistor, laser, cell phone, solar cell, negative feedback amplifier, communications satellite and many others were made there. Scientific breakthroughs such as discovery of the Big Bang, the wave nature of the electron, electron localization and the fractional quantum hall effect were also made there making Bell Labs almost unique in terms of large impacts in both science and technology. In my talk, I will discuss the history of the lab, talk about the present and give some suggestions for how I see it evolving into the future.

Undergraduate Labs for Biological Physics: Brownian Motion and Optical Trapping

NASA Astrophysics Data System (ADS)

Chu, Kelvin; Laughney, A.; Williams, J.

2006-12-01

We describe a set of case-study driven labs for an upper-division biological physics course. These labs are motivated by case-studies and consist of inquiry-driven investigations of Brownian motion and optical-trapping experiments. Each lab incorporates two innovative educational techniques to drive the process and application aspects of scientific learning. Case studies are used to encourage students to think independently and apply the scientific method to a novel lab situation. Student input from this case study is then used to decide how to best do the measurement, guide the project and ultimately evaluate the success of the program. Where appropriate, visualization and simulation using VPython is used. Direct visualization of Brownian motion allows students to directly calculate Avogadro's number or the Boltzmann constant. Following case-study driven discussion, students use video microscopy to measure the motion of latex spheres in different viscosity fluids arrive at a good approximation of NA or kB. Optical trapping (laser tweezer) experiments allow students to investigate the consequences of 100-pN forces on small particles. The case study consists of a discussion of the Boltzmann distribution and equipartition theorem followed by a consideration of the shape of the potential. Students can then use video capture to measure the distribution of bead positions to determine the shape and depth of the trap. This work supported by NSF DUE-0536773.

Making ideas at scientific fabrication laboratories

NASA Astrophysics Data System (ADS)

Fonda, Carlo; Canessa, Enrique

2016-11-01

Creativity, together with the making of ideas into fruition, is essential for progress. Today the evolution from an idea to its application can be facilitated by the implementation of Fabrication Laboratories, or FabLabs, having affordable digital tools for prototyping. FabLabs aiming at scientific research and invention are now starting to be established inside Universities, Research Centers and Schools. We review the setting up of the ICTP Scientific FabLab in Trieste, Italy, give concrete examples on the use in physics, and propose to replicate world-wide this class of multi-purpose workplaces within academia as a support for physics and math education and for community development.

Using Affinity Chromatography to Investigate Novel Protein–Protein Interactions in an Undergraduate Cell and Molecular Biology Lab Course

PubMed Central

2009-01-01

Inquiry-driven lab exercises require students to think carefully about a question, carry out an investigation of that question, and critically analyze the results of their investigation. Here, we describe the implementation and assessment of an inquiry-based laboratory exercise in which students obtain and analyze novel data that contribute to our understanding of macromolecular trafficking between the nucleus and cytoplasm in eukaryotic cells. Although many of the proteins involved in nucleocytoplasmic transport are known, the physical interactions between some of these polypeptides remain uncharacterized. In this cell and molecular biology lab exercise, students investigate novel protein–protein interactions between factors involved in nuclear RNA export. Using recombinant protein expression, protein extraction, affinity chromatography, SDS-polyacrylamide gel electrophoresis, and Western blotting, undergraduates in a sophomore-level lab course identified a previously unreported association between the soluble mRNA transport factor Mex67 and the C-terminal region of the yeast nuclear pore complex protein Nup1. This exercise immersed students in the process of investigative science, from proposing and performing experiments through analyzing data and reporting outcomes. On completion of this investigative lab sequence, students reported enhanced understanding of the scientific process, increased proficiency with cellular and molecular methods and content, greater understanding of data analysis and the importance of appropriate controls, an enhanced ability to communicate science effectively, and an increased enthusiasm for scientific research and for the lab component of the course. The modular nature of this exercise and its focus on asking novel questions about protein–protein interactions make it easily transferable to undergraduate lab courses performed in a wide variety of contexts. PMID:19723816

Conference Committees: Conference Committees

NASA Astrophysics Data System (ADS)

2009-09-01

International Programm Committee (IPC) Harald Ade NCSU Sadao Aoki University Tsukuba David Attwood Lawrence Berkeley National Laboratory/CXRO Christian David Paul Scherrer Institut Peter Fischer Lawrence Berkeley National Laboratory Adam Hitchcock McMaster University Chris Jacobsen SUNY, Stony Brook Denis Joyeux Lab Charles Fabry de l'Institut d'Optique Yasushi Kagoshima University of Hyogo Hiroshi Kihara Kansai Medical University Janos Kirz SUNY Stony Brook Maya Kiskinova ELETTRA Ian McNulty Argonne National Lab/APS Alan Michette Kings College London Graeme Morrison Kings College London Keith Nugent University of Melbourne Zhu Peiping BSRF Institute of High Energy Physics Francois Polack Soleil Christoph Quitmann Paul Scherrer Institut Günther Schmahl University Göttingen Gerd Schneider Bessy Hyun-Joon Shin Pohang Accelerator Lab Jean Susini ESRF Mau-Tsu Tang NSRRC Tony Warwick Lawrence Berkeley Lab/ALS Local Organizing Committee Christoph Quitmann Chair, Scientific Program Charlotte Heer Secretary Christian David Scientific Program Frithjof Nolting Scientific Program Franz Pfeiffer Scientific Program Marco Stampanoni Scientific Program Robert Rudolph Sponsoring, Financials Alfred Waser Industry Exhibition Robert Keller Public Relation Markus Knecht Computing and WWW Annick Cavedon Proceedings and Excursions and Accompanying Persons Program Margrit Eichler Excursions and Accompanying Persons Program Kathy Eikenberry Excursions and Accompanying Persons Program Marlies Locher Excursions and Accompanying Persons Program

Definition of the upper reference limit for thyroglobulin antibodies according to the National Academy of Clinical Biochemistry guidelines: comparison of eleven different automated methods.

PubMed

D'Aurizio, F; Metus, P; Ferrari, A; Caruso, B; Castello, R; Villalta, D; Steffan, A; Gaspardo, K; Pesente, F; Bizzaro, N; Tonutti, E; Valverde, S; Cosma, C; Plebani, M; Tozzoli, R

2017-12-01

In the last two decades, thyroglobulin autoantibodies (TgAb) measurement has progressively switched from marker of thyroid autoimmunity to test associated with thyroglobulin (Tg) to verify the presence or absence of TgAb interference in the follow-up of patients with differentiated thyroid cancer. Of note, TgAb measurement is cumbersome: despite standardization against the International Reference Preparation MRC 65/93, several studies demonstrated high inter-method variability and wide variation in limits of detection and in reference intervals. Taking into account the above considerations, the main aim of the present study was the determination of TgAb upper reference limit (URL), according to the National Academy of Clinical Biochemistry guidelines, through the comparison of eleven commercial automated immunoassay platforms. The sera of 120 healthy males, selected from a population survey in the province of Verona, Italy, were tested for TgAb concentration using eleven IMA applied on as many automated analyzers: AIA-2000 (AIA) and AIA-CL2400 (CL2), Tosoh Bioscience; Architect (ARC), Abbott Diagnostics; Advia Centaur XP (CEN) and Immulite 2000 XPi (IMM), Siemens Healthineers; Cobas 6000 (COB), Roche Diagnostics; Kryptor (KRY), Thermo Fisher Scientific BRAHMS, Liaison XL (LIA), Diasorin; Lumipulse G (LUM), Fujirebio; Maglumi 2000 Plus (MAG), Snibe and Phadia 250 (PHA), Phadia AB, Thermo Fisher Scientific. All assays were performed according to manufacturers' instructions in six different laboratories in Friuli-Venezia Giulia and Veneto regions of Italy [Lab 1 (AIA), Lab 2 (CL2), Lab 3 (ARC, COB and LUM), Lab 4 (CEN, IMM, KRY and MAG), Lab 5 (LIA) and Lab 6 (PHA)]. Since TgAb values were not normally distributed, the experimental URL (e-URL) was established at 97.5 percentile according to the non-parametric method. TgAb e-URLs showed a significant inter-method variability. Considering the same method, e-URL was much lower than that suggested by manufacturers (m-URL), except for ARC and MAG. Correlation and linear regression were unsatisfactory. Consequently, the agreement between methods was poor, with significant bias in Bland-Altman plot. Despite the efforts for harmonization, TgAb methods cannot be used interchangeably. Therefore, additional effort is required to improve analytical performance taking into consideration approved protocols and guidelines. Moreover, TgAb URL should be used with caution in the management of differentiated thyroid carcinoma patients since the presence and/or the degree of TgAb interference in Tg measurement has not yet been well defined.

Scientific Visualization, Seeing the Unseeable

ScienceCinema

LBNL

2017-12-09

June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in bo... June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in both experimental and computational sciences. Wes Bethel, who heads the Scientific Visualization Group in the Computational Research Division, presents an overview of visualization and computer graphics, current research challenges, and future directions for the field.

Teaching Lab Report Writing through Inquiry: A Green Chemistry Stoichiometry Experiment for General Chemistry

ERIC Educational Resources Information Center

Cacciatore, Kristen L.; Sevian, Hannah

2006-01-01

We present an alternative to a traditional first-year chemistry laboratory experiment. This experiment has four key features: students utilize stoichiometry, learn and apply principles of green chemistry, engage in authentic scientific inquiry, and discover why each part of a scientific lab report is necessary. The importance and essential…

Teaching Stress Physiology Using Zebrafish ("Danio Rerio")

ERIC Educational Resources Information Center

Cooper, Michael; Dhawale, Shree; Mustafa, Ahmed

2009-01-01

A straightforward and inexpensive laboratory experiment is presented that investigates the physiological stress response of zebrafish after a 5 degree C increase in water temperature. This experiment is designed for an undergraduate physiology lab and allows students to learn the scientific method and relevant laboratory techniques without causing…

Science and General Education: Reactions From A Generalist

ERIC Educational Resources Information Center

McQuigg, R. Bruce

1972-01-01

Author says that science courses that develop contempt for and hostility toward science are doing more harm than good to many students, and calls on curriculum makers to see that respect for the scientific method is engendered by translating it from the lab to life itself. (Editor)

Broadcasting a Lab Measurement over Existing Conductor Networks

ERIC Educational Resources Information Center

Knipp, Peter A.

2009-01-01

Students learn about physical laws and the scientific method when they analyze experimental data in a laboratory setting. Three common sources exist for the experimental data that they analyze: (1) "hands-on" measurements by the students themselves, (2) electronic transfer (by downloading a spreadsheet, video, or computer-aided data-acquisition…

Mentor-Mentee Interaction and Laboratory Social Environment: Do They Matter in Doctoral Students' Publication Productivity?

ERIC Educational Resources Information Center

Ynalvez, Marcus Antonius; Ynalvez, Ruby A.; Ramírez, Enrique

2017-01-01

We explored the social shaping of science at the micro-level reality of face-to-face interaction in one of the traditional places for scientific activities--the scientific lab. We specifically examined how doctoral students' perception of their: (i) interaction with doctoral mentors (MMI) and (ii) lab social environment (LSE) influenced…

The StratusLab cloud distribution: Use-cases and support for scientific applications

NASA Astrophysics Data System (ADS)

Floros, E.

2012-04-01

The StratusLab project is integrating an open cloud software distribution that enables organizations to setup and provide their own private or public IaaS (Infrastructure as a Service) computing clouds. StratusLab distribution capitalizes on popular infrastructure virtualization solutions like KVM, the OpenNebula virtual machine manager, Claudia service manager and SlipStream deployment platform, which are further enhanced and expanded with additional components developed within the project. The StratusLab distribution covers the core aspects of a cloud IaaS architecture, namely Computing (life-cycle management of virtual machines), Storage, Appliance management and Networking. The resulting software stack provides a packaged turn-key solution for deploying cloud computing services. The cloud computing infrastructures deployed using StratusLab can support a wide range of scientific and business use cases. Grid computing has been the primary use case pursued by the project and for this reason the initial priority has been the support for the deployment and operation of fully virtualized production-level grid sites; a goal that has already been achieved by operating such a site as part of EGI's (European Grid Initiative) pan-european grid infrastructure. In this area the project is currently working to provide non-trivial capabilities like elastic and autonomic management of grid site resources. Although grid computing has been the motivating paradigm, StratusLab's cloud distribution can support a wider range of use cases. Towards this direction, we have developed and currently provide support for setting up general purpose computing solutions like Hadoop, MPI and Torque clusters. For what concerns scientific applications the project is collaborating closely with the Bioinformatics community in order to prepare VM appliances and deploy optimized services for bioinformatics applications. In a similar manner additional scientific disciplines like Earth Science can take advantage of StratusLab cloud solutions. Interested users are welcomed to join StratusLab's user community by getting access to the reference cloud services deployed by the project and offered to the public.

Small Private Online Research: A Proposal for A Numerical Methods Course Based on Technology Use and Blended Learning

ERIC Educational Resources Information Center

Cepeda, Francisco Javier Delgado

2017-01-01

This work presents a proposed model in blended learning for a numerical methods course evolved from traditional teaching into a research lab in scientific visualization. The blended learning approach sets a differentiated and flexible scheme based on a mobile setup and face to face sessions centered on a net of research challenges. Model is…

Using Mini-Reports to Teach Scientific Writing to Biology Students

ERIC Educational Resources Information Center

Simmons, Alexandria D.; Larios-Sanz, Maia; Amin, Shivas; Rosell, Rosemarie C.

2014-01-01

Anyone who has taught an introductory biology lab has sat at their desk in front of a towering stack of lengthy lab reports and wondered if there was a better way to teach scientific writing. We propose the use of a one-page format that we have called a "mini-report," which we believe better allows students to understand the structure…

Incorporating a Literature-Based Learning Approach into a Lab Course to Increase Student Understanding

ERIC Educational Resources Information Center

Parent, Beth A.; Marbach-Ad, Gili; Swanson, Karen V.; Smith, Ann C.

2010-01-01

Scientific literature was used to give a research oriented context to our immunology lab course. Immunology lab, a senior level course (60 students/year) was formerly taught in a traditional mode, with exercises aimed at learning lab protocols. To engage students in understanding we connected the protocols to their use as reported in research…

Do Policies that Encourage Better Attendance in Lab Change Students' Academic Behaviors and Performances in Introductory Science Courses?

ERIC Educational Resources Information Center

Moore, Randy; Jensen, Philip A.

2008-01-01

Science courses with hands-on investigative labs are a typical part of the general education requirements at virtually all colleges and universities. In these courses, labs that satisfy a curricular requirement for "lab experience" are important because they provide the essence of the scientific experience--that is, they give students…

Value Added or Misattributed? A Multi-Institution Study on the Educational Benefit of Labs for Reinforcing Physics Content

ERIC Educational Resources Information Center

Holmes, N. G.; Olsen, Jack; Thomas, James L.; Wieman, Carl E.

2017-01-01

Instructional labs are widely seen as a unique, albeit expensive, way to teach scientific content. We measured the effectiveness of introductory lab courses at achieving this educational goal across nine different lab courses at three very different institutions. These institutions and courses encompassed a broad range of student populations and…

Behind the Scenes at Berkeley Lab - The Mechanical Fabrication Facility

ScienceCinema

Wells, Russell; Chavez, Pete; Davis, Curtis; Bentley, Brian

2018-04-16

Part of the Behind the Scenes series at Berkeley Lab, this video highlights the lab's mechanical fabrication facility and its exceptional ability to produce unique tools essential to the lab's scientific mission. Through a combination of skilled craftsmanship and precision equipment, machinists and engineers work with scientists to create exactly what's needed - whether it's measured in microns or meters.

Magic Termites: Exploring Scientific Inquiry

ERIC Educational Resources Information Center

Callis, Kristine; Henkel, Melissa; Lund, Rachael

2010-01-01

The objective of the termite experiment is to walk students through the process of designing and conducting an experiment while allowing them to use inquiry-based methods to infer why, in this lab, termites follow the line of blue Bic or Paper Mate brand ballpoint pens. This experiment also reinforces the concept of observation versus inference…

Army Reserve Component Personal Empowerment Program #2t

DTIC Science & Technology

2013-10-01

rescheduling of appointments • Retrieved lab reports from hospital lab for 161 participants 8 • Identified abnormal values and sent copies to campus nurse ...recommendation of SHU Scientific Committee • Collaborated with SHU nurse to establish procedure for abnormal lab values • Implemented suggested...results were encouraged to discuss further with nurse as per protocol. • Researched literature concerning vitamin D to better understand lab results

Creating a lab to facilitate high school student engagement in authentic paleoclimate science practices

NASA Astrophysics Data System (ADS)

Maloney, A.; Walsh, E.

2012-12-01

A solid understanding of timescales is crucial for any climate change discussion. This hands-on lab was designed as part of a dual-credit climate change course in which high school students can receive college credit. Using homemade ice cores, students have the opportunity to participate in scientific practices associated with collecting, processing, and interpreting temperature and CO2 data. Exploring millennial-scale cycles in ice core data and extending the CO2 record to the present allows students to discover timescales from an investigators perspective. The Ice Core Lab has been piloted in two high school classrooms and student engagement, and epistemological and conceptual understanding was evaluated using quantitative pre and post assessment surveys. The process of creating this lab involved a partnership between an education assessment professional, high school teachers, and University of Washington professors and graduate students in Oceanography, Earth and Space Sciences, Atmospheric Sciences and the Learning Sciences as part of the NASA Global Climate Change University of Washington in the High School program. This interdisciplinary collaboration led to the inception of the lab and was necessary to ensure that the lesson plan was pedagogically appropriate and scientifically accurate. The lab fits into a unit about natural variability and is paired with additional hands-on activities created by other graduate students that explore short-timescale temperature variations, Milankovitch cycles, isotopes, and other proxies. While the Ice Core Lab is intended to follow units that review the scientific process, global energy budget, and transport, it can be modified to fit any teaching platform.

Effectiveness of Learning with 3D-Lab on Omani Basic Education Students' Achievement, Attitudes and Scientific Thinking

ERIC Educational Resources Information Center

Musawi, Ali Al; Ambusaidi, Abdullah; Al-Balushi, Sulaiman; Al-Sinani, Mohamed; Al-Balushi, Kholoud

2017-01-01

This paper aims to measure the effectiveness of the 3DL on Omani students' acquisition of practical abilities and skills. It examines the effectiveness of the 3D-lab in science education and scientific thinking acquisition as part of a national project funded by The Research Council. Four research tools in a Pre-Post Test Control Group Design,…

How Do You Like Your Science, Wet or Dry? How Two Lab Experiences Influence Student Understanding of Science Concepts and Perceptions of Authentic Scientific Practice

PubMed Central

Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W.; Levias, Sheldon

2017-01-01

This study examines how two kinds of authentic research experiences related to smoking behavior—genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)—influence students’ perceptions and understanding of scientific research and related science concepts. The study used pre and post surveys and a focus group protocol to compare students who conducted the research experiences in one of two sequences: genotyping before database and database before genotyping. Students rated the genotyping experiment to be more like real science than the database experiment, in spite of the fact that they associated more scientific tasks with the database experience than genotyping. Independent of the order of completing the labs, students showed gains in their understanding of science concepts after completion of the two experiences. There was little change in students’ attitudes toward science pre to post, as measured by the Scientific Attitude Inventory II. However, on the basis of their responses during focus groups, students developed more sophisticated views about the practices and nature of science after they had completed both research experiences, independent of the order in which they experienced them. PMID:28572181

Science Is an Action Word! Grades 1-3.

ERIC Educational Resources Information Center

Perdue, Peggy K.

This book includes 20 science activities in the fields of scientific method, earth science, life science, and physical science. Each activity is composed of two parts--an explanatory section for the teacher and a student lab sheet. The explanatory section begins with a brief introduction designed to give an overview of the activity's main concept.…

Podcast: Scientific Integrity and Lab Fraud

EPA Pesticide Factsheets

Nov 25, 2015. Dr. Bruce Woods, a chemist in the Electronic Crimes Division within the OIG’s Office of Investigations discusses his recent webinar for the Association of Public Health Laboratories on lab fraud.

Measure, Then Show: Grasping Human Evolution Through an Inquiry-Based, Data-driven Hominin Skulls Lab.

PubMed

Bayer, Chris N; Luberda, Michael

2016-01-01

Incomprehension and denial of the theory of evolution among high school students has been observed to also occur when teachers are not equipped to deliver a compelling case also for human evolution based on fossil evidence. This paper assesses the outcomes of a novel inquiry-based paleoanthropology lab teaching human evolution to high-school students. The inquiry-based Be a Paleoanthropologist for a Day lab placed a dozen hominin skulls into the hands of high-school students. Upon measuring three variables of human evolution, students explain what they have observed and discuss findings. In the 2013/14 school year, 11 biology classes in 7 schools in the Greater New Orleans area participated in this lab. The interviewed teacher cohort unanimously agreed that the lab featuring hominin skull replicas and stimulating student inquiry was a pedagogically excellent method of delivering the subject of human evolution. First, the lab's learning path of transforming facts to data, information to knowledge, and knowledge to acceptance empowered students to themselves execute part of the science that underpins our understanding of deep time hominin evolution. Second, although challenging, the hands-on format of the lab was accessible to high-school students, most of whom were readily able to engage the lab's scientific process. Third, the lab's exciting and compelling pedagogy unlocked higher order thinking skills, effectively activating the cognitive, psychomotor and affected learning domains as defined in Bloom's taxonomy. Lastly, the lab afforded students a formative experience with a high degree of retention and epistemic depth. Further study is warranted to gauge the degree of these effects.

ASK4Labs: A Web-Based Repository for Supporting Learning Design Driven Remote and Virtual Labs Recommendations

ERIC Educational Resources Information Center

Zervas, Panagiotis; Fiskilis, Stefanos; Sampson, Demetrios G.

2014-01-01

Over the past years, Remote and Virtual Labs (RVLs) have gained increased attention for their potential to support technology-enhanced science education by enabling science teachers to improve their day-to-day science teaching. Therefore, many educational institutions and scientific organizations have invested efforts for providing online access…

Improve Data Mining and Knowledge Discovery Through the Use of MatLab

NASA Technical Reports Server (NTRS)

Shaykhian, Gholam Ali; Martin, Dawn (Elliott); Beil, Robert

2011-01-01

Data mining is widely used to mine business, engineering, and scientific data. Data mining uses pattern based queries, searches, or other analyses of one or more electronic databases/datasets in order to discover or locate a predictive pattern or anomaly indicative of system failure, criminal or terrorist activity, etc. There are various algorithms, techniques and methods used to mine data; including neural networks, genetic algorithms, decision trees, nearest neighbor method, rule induction association analysis, slice and dice, segmentation, and clustering. These algorithms, techniques and methods used to detect patterns in a dataset, have been used in the development of numerous open source and commercially available products and technology for data mining. Data mining is best realized when latent information in a large quantity of data stored is discovered. No one technique solves all data mining problems; challenges are to select algorithms or methods appropriate to strengthen data/text mining and trending within given datasets. In recent years, throughout industry, academia and government agencies, thousands of data systems have been designed and tailored to serve specific engineering and business needs. Many of these systems use databases with relational algebra and structured query language to categorize and retrieve data. In these systems, data analyses are limited and require prior explicit knowledge of metadata and database relations; lacking exploratory data mining and discoveries of latent information. This presentation introduces MatLab(R) (MATrix LABoratory), an engineering and scientific data analyses tool to perform data mining. MatLab was originally intended to perform purely numerical calculations (a glorified calculator). Now, in addition to having hundreds of mathematical functions, it is a programming language with hundreds built in standard functions and numerous available toolboxes. MatLab's ease of data processing, visualization and its enormous availability of built in functionalities and toolboxes make it suitable to perform numerical computations and simulations as well as a data mining tool. Engineers and scientists can take advantage of the readily available functions/toolboxes to gain wider insight in their perspective data mining experiments.

Improve Data Mining and Knowledge Discovery through the use of MatLab

NASA Technical Reports Server (NTRS)

Shaykahian, Gholan Ali; Martin, Dawn Elliott; Beil, Robert

2011-01-01

Data mining is widely used to mine business, engineering, and scientific data. Data mining uses pattern based queries, searches, or other analyses of one or more electronic databases/datasets in order to discover or locate a predictive pattern or anomaly indicative of system failure, criminal or terrorist activity, etc. There are various algorithms, techniques and methods used to mine data; including neural networks, genetic algorithms, decision trees, nearest neighbor method, rule induction association analysis, slice and dice, segmentation, and clustering. These algorithms, techniques and methods used to detect patterns in a dataset, have been used in the development of numerous open source and commercially available products and technology for data mining. Data mining is best realized when latent information in a large quantity of data stored is discovered. No one technique solves all data mining problems; challenges are to select algorithms or methods appropriate to strengthen data/text mining and trending within given datasets. In recent years, throughout industry, academia and government agencies, thousands of data systems have been designed and tailored to serve specific engineering and business needs. Many of these systems use databases with relational algebra and structured query language to categorize and retrieve data. In these systems, data analyses are limited and require prior explicit knowledge of metadata and database relations; lacking exploratory data mining and discoveries of latent information. This presentation introduces MatLab(TradeMark)(MATrix LABoratory), an engineering and scientific data analyses tool to perform data mining. MatLab was originally intended to perform purely numerical calculations (a glorified calculator). Now, in addition to having hundreds of mathematical functions, it is a programming language with hundreds built in standard functions and numerous available toolboxes. MatLab's ease of data processing, visualization and its enormous availability of built in functionalities and toolboxes make it suitable to perform numerical computations and simulations as well as a data mining tool. Engineers and scientists can take advantage of the readily available functions/toolboxes to gain wider insight in their perspective data mining experiments.

WeFold: A Coopetition for Protein Structure Prediction

PubMed Central

Khoury, George A.; Liwo, Adam; Khatib, Firas; Zhou, Hongyi; Chopra, Gaurav; Bacardit, Jaume; Bortot, Leandro O.; Faccioli, Rodrigo A.; Deng, Xin; He, Yi; Krupa, Pawel; Li, Jilong; Mozolewska, Magdalena A.; Sieradzan, Adam K.; Smadbeck, James; Wirecki, Tomasz; Cooper, Seth; Flatten, Jeff; Xu, Kefan; Baker, David; Cheng, Jianlin; Delbem, Alexandre C. B.; Floudas, Christodoulos A.; Keasar, Chen; Levitt, Michael; Popović, Zoran; Scheraga, Harold A.; Skolnick, Jeffrey; Crivelli, Silvia N.; Players, Foldit

2014-01-01

The protein structure prediction problem continues to elude scientists. Despite the introduction of many methods, only modest gains were made over the last decade for certain classes of prediction targets. To address this challenge, a social-media based worldwide collaborative effort, named WeFold, was undertaken by thirteen labs. During the collaboration, the labs were simultaneously competing with each other. Here, we present the first attempt at “coopetition” in scientific research applied to the protein structure prediction and refinement problems. The coopetition was possible by allowing the participating labs to contribute different components of their protein structure prediction pipelines and create new hybrid pipelines that they tested during CASP10. This manuscript describes both successes and areas needing improvement as identified throughout the first WeFold experiment and discusses the efforts that are underway to advance this initiative. A footprint of all contributions and structures are publicly accessible at http://www.wefold.org. PMID:24677212

Engineering Design Handbook. Explosions in Air. Part One

DTIC Science & Technology

1974-07-15

Characteristics in the 6. R. E. Shear, Detonation Properties of Calculation of Non-Steady Compressible Pentolite, BRL Rept. No. 1159, 1961. Flows, Los Alamos ...6 (June 1955). Particle-and-Force Method, Los Alamos Sci. Lab., LA 3144, September 1964. 19. H. L Brode, Point Source Explosion in Air, The Rand Corp...RM-1824-AEC, 29. F. H. Harlow and B. D. Meixner, The December 3, 1956. Particle-and-Force Computing Method in Fluid Dynamics, Los Alamos Scientific

Developing automated analytical methods for scientific environments using LabVIEW.

PubMed

Wagner, Christoph; Armenta, Sergio; Lendl, Bernhard

2010-01-15

The development of new analytical techniques often requires the building of specially designed devices, each requiring its own dedicated control software. Especially in the research and development phase, LabVIEW has proven to be one highly useful tool for developing this software. Yet, it is still common practice to develop individual solutions for different instruments. In contrast to this, we present here a single LabVIEW-based program that can be directly applied to various analytical tasks without having to change the program code. Driven by a set of simple script commands, it can control a whole range of instruments, from valves and pumps to full-scale spectrometers. Fluid sample (pre-)treatment and separation procedures can thus be flexibly coupled to a wide range of analytical detection methods. Here, the capabilities of the program have been demonstrated by using it for the control of both a sequential injection analysis - capillary electrophoresis (SIA-CE) system with UV detection, and an analytical setup for studying the inhibition of enzymatic reactions using a SIA system with FTIR detection.

Using OpenTarget to Generate Potential Countermeasures for Long-Term Space Exposure from Data Available on GeneLab

NASA Technical Reports Server (NTRS)

Beheshti, Afshin

2018-01-01

GeneLab as a general tool for the scientific community; Utilizing GeneLab datasets to generate hypothesis and determining potential biological targets against health risks due to long-term space missions; How can OpenTarget be used to discover novel drugs to test as countermeasures that can be utilized by astronauts.

MatLab Programming for Engineers Having No Formal Programming Knowledge

NASA Technical Reports Server (NTRS)

Shaykhian, Linda H.; Shaykhian, Gholam Ali

2007-01-01

MatLab is one of the most widely used very high level programming languages for Scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. Also, stated are the current limitations of the MatLab, which possibly can be taken care of by Mathworks Inc. in a future version to make MatLab more versatile.

Exploring problem-based cooperative learning in undergraduate physics labs: student perspectives

NASA Astrophysics Data System (ADS)

Bergin, S. D.; Murphy, C.; Shuilleabhain, A. Ni

2018-03-01

This study examines the potential of problem-based cooperative learning (PBCL) in expanding undergraduate physics students’ understanding of, and engagement with, the scientific process. Two groups of first-year physics students (n = 180) completed a questionnaire which compared their perceptions of learning science with their engagement in physics labs. One cohort completed a lab based on a PBCL approach, whilst the other completed the same experiment, using a more traditional, manual-based lab. Utilising a participant research approach, the questionnaire was co-constructed by researchers and student advisers from each cohort in order to improve shared meaning between researchers and participants. Analysis of students’ responses suggests that students in the PBCL cohort engaged more in higher-order problem-solving skills and evidenced a deeper understanding of the scientific process than students in the more traditional, manual-based cohort. However, the latter cohort responses placed more emphasis on accuracy and measurement in lab science than the PBCL cohort. The students in the PBCL cohort were also more positively engaged with their learning than their counterparts in the manual led group.

MatLab Script and Functional Programming

NASA Technical Reports Server (NTRS)

Shaykhian, Gholam Ali

2007-01-01

MatLab Script and Functional Programming: MatLab is one of the most widely used very high level programming languages for scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. The MatLab seminar covers the functional and script programming aspect of MatLab language. Specific expectations are: a) Recognize MatLab commands, script and function. b) Create, and run a MatLab function. c) Read, recognize, and describe MatLab syntax. d) Recognize decisions, loops and matrix operators. e) Evaluate scope among multiple files, and multiple functions within a file. f) Declare, define and use scalar variables, vectors and matrices.

50 years of service: The Missoula Fire Sciences Lab

Treesearch

Jane Kapler Smith; Diane Smith; Colin Hardy

2011-01-01

In September 12, 1960, the brand new Northern Forest Fire Laboratory was dedicated in Missoula, MT. The fire lab’s mission was - and is - to improve scientific understanding of wildland fire so it can be managed more safely and effectively in the field. The first scientists to work at the fire lab initiated research that continues to be used, refined, and extended....

Teaching resources. The Sherlock Holmes lab: investigations in neurophysiology.

PubMed

Adler, Elizabeth M; Schwartz, Paul J

2006-05-09

This Teaching Resource describes a research project that can be used in an advanced undergraduate course in neurobiology that covers basic electrophysiology and synaptic transmission. A thought experiment is provided that can be used to assess student understanding of (i) the scientific method, (ii) the process whereby nerve stimulation leads to muscle contraction, and (iii) the use of pharmacological agents to analyze a physiological system.

A Scientific Approach To STEM Education

DTIC Science & Technology

2011-06-16

T My Physics graduate students -- Why excellence in physics courses≠ competence in physics research ? Two years in lab transforms? approached as...learned? (100’s of courses/yr) improved methods average trad. Cal Poly instruction 2. Multiple instructors facilitating same established set of student ...Intro biology Univ. of Wash.– similar research - based instruction •All students improve •Underrepresented students improve more (+1/3 letter grade

Geology in the Movies: Using Hollywood Films as a Teaching Tool in Introductory Geosciences Courses

NASA Astrophysics Data System (ADS)

Lawrence, K. T.; Malinconico, L. L.

2008-12-01

A common challenge in introductory Geoscience courses is engaging students who often do not have a long- standing interest in science. In recent years Hollywood has produced a number of geoscience-themed films (Dante's Peak, Deep Impact, Day After Tomorrow, Inconvenient Truth), most of which contain kernels of scientific truth as well as gross misrepresentations of scientific reality. In our introductory courses (Geological Disasters: Agents of Chaos and Earth's Climate: Past Present and Future) we have had great success using these films as a way of both engaging students and accomplishing many of our course goals. Even though most of the students in these courses will not become geoscience majors, it is important for them to realize that they can make informed judgments about concepts portrayed in the popular media. We have incorporated short written movie critiques into our suite of introductory course laboratory exercises. Through these movie-critique labs, students have an opportunity to apply their new geoscience expertise to examining the validity of the scientific concepts presented in the film. Along the way, students start to see the relevance of course materials to their everyday lives, think more critically about how science is portrayed by non-scientists, synthesize what they have learned by applying their knowledge to a new problem, and improve their ability to communicate what they have learned. Despite the fact that these movie-critique labs require significantly more out-of-lab effort that our other introductory lab assignments, in our course evaluations many students rate the movie critiques as not only one of the most interesting lab exercises of the semester, but also the lab exercise containing the most educational value.

Recommendations for the use of notebooks in upper-division physics lab courses

NASA Astrophysics Data System (ADS)

Stanley, Jacob T.; Lewandowski, H. J.

2018-01-01

The use of lab notebooks for scientific documentation is a ubiquitous part of physics research. However, it is common for undergraduate physics laboratory courses not to emphasize the development of documentation skills, despite the fact that such courses are some of the earliest opportunities for students to start engaging in this practice. One potential impediment to the inclusion of explicit documentation training is that it may be unclear to instructors which features of authentic documentation practice are efficacious to teach and how to incorporate these features into the lab class environment. In this work, we outline some of the salient features of authentic documentation, informed by interviews with physics researchers, and provide recommendations for how these can be incorporated into the lab curriculum. We do not focus on structural details or templates for notebooks. Instead, we address holistic considerations for the purpose of scientific documentation that can guide students to develop their own documentation style. While taking into consideration all the aspects that can help improve students' documentation, it is also important to consider the design of the lab activities themselves. Students should have experience with implementing these authentic features of documentation during lab activities in order for them to find practice with documentation beneficial.

Economic impact

DOE Office of Scientific and Technical Information (OSTI.GOV)

Technology Transfer Department

2001-06-01

In federal fiscal year 2000 (FY00), Berkeley Lab had 4,347 full- and part-time employees. In addition, at any given time of the year, there were more than 1,000 Laboratory guests. These guests, who also reside locally, have an important economic impact on the nine-county Bay Area. However, Berkeley Lab's total economic impact transcends the direct effects of payroll and purchasing. The direct dollars paid to the Lab's employees in the form of wages, salaries, and benefits, and payments made to contractors for goods and services, are respent by employees and contractors again and again in the local and greater economy.more » Further, while Berkeley Lab has a strong reputation for basic scientific research, many of the Lab's scientific discoveries and inventions have had direct application in industry, spawning new businesses and creating new opportunities for existing firms. This analysis updates the Economic Impact Analysis done in 1996, and its purpose is to describe the economic and geographic impact of Laboratory expenditures and to provide a qualitative understanding of how Berkeley Lab impacts and supports the local community. It is intended as a guide for state, local, and national policy makers as well as local community members. Unless otherwise noted, this analysis uses data from FY00, the most recent year for which full data are available.« less

Integration of MSFC Usability Lab with Usability Testing

NASA Technical Reports Server (NTRS)

Cheng, Yiwei; Richardson, Sally

2010-01-01

As part of the Stage Analysis Branch, human factors engineering plays an important role in relating humans to the systems of hardware and structure designs of the new launch vehicle. While many branches are involved in the technical aspects of creating a launch vehicle, human factors connects humans to the scientific systems with the goal of improving operational performance and safety while reducing operational error and damage to the hardware. Human factors engineers use physical and computerized models to visualize possible areas for improvements to ensure human accessibility to components requiring maintenance and that the necessary maintenance activities can be accomplished with minimal risks to human and hardware. Many methods of testing are used to fulfill this goal, such as physical mockups, computerized visualization, and usability testing. In this analysis, a usability test is conducted to test how usable a website is to users who are and are not familiar with it. The testing is performed using participants and Morae software to record and analyze the results. This analysis will be a preliminary test of the usability lab in preparation for use in new spacecraft programs, NASA Enterprise, or other NASA websites. The usability lab project is divided into two parts: integration of the usability lab and a preliminary test of the usability lab.

Gulf Breeze, FL Lab--Office of Research and Development

EPA Pesticide Factsheets

The Gulf Breeze lab is recognized as a leader in advancing scientific knowledge concerning the effects of human-made stressors on the ecosystems of the Gulf Coast, and the impacts of those effects on the health and well-being of people and communities.

Recontextualization of Science from Lab to School: Implications for Science Literacy

ERIC Educational Resources Information Center

Sharma, Ajay; Anderson, Charles W.

2009-01-01

Scientists' science differs remarkably from school science. In order to be taught to students, science is recontextualized from scientific research communities to science classrooms. This paper examines scientific discourse in scientific research communities, and discusses its transformation from an internally-persuasive and authoritative…

High-resolution 3D imaging of polymerized photonic crystals by lab-based x-ray nanotomography with 50-nm resolution

NASA Astrophysics Data System (ADS)

Yin, Leilei; Chen, Ying-Chieh; Gelb, Jeff; Stevenson, Darren M.; Braun, Paul A.

2010-09-01

High resolution x-ray computed tomography is a powerful non-destructive 3-D imaging method. It can offer superior resolution on objects that are opaque or low contrast for optical microscopy. Synchrotron based x-ray computed tomography systems have been available for scientific research, but remain difficult to access for broader users. This work introduces a lab-based high-resolution x-ray nanotomography system with 50nm resolution in absorption and Zernike phase contrast modes. Using this system, we have demonstrated high quality 3-D images of polymerized photonic crystals which have been analyzed for band gap structures. The isotropic volumetric data shows excellent consistency with other characterization results.

Athens, GA Lab--Office of Research and Development

EPA Pesticide Factsheets

The EPA laboratory in Athens, GA is a recognized leader in advancing and implementing scientific knowledge, and providing scientific and technical support tailored to environmental concerns and issues in the Southeast U.S.

Curriculum Alignment with Vision and Change Improves Student Scientific Literacy

PubMed Central

Auerbach, Anna Jo; Schussler, Elisabeth E.

2017-01-01

The Vision and Change in Undergraduate Biology Education final report challenged institutions to reform their biology courses to focus on process skills and student active learning, among other recommendations. A large southeastern university implemented curricular changes to its majors’ introductory biology sequence in alignment with these recommendations. Discussion sections focused on developing student process skills were added to both lectures and a lab, and one semester of lab was removed. This curriculum was implemented using active-learning techniques paired with student collaboration. This study determined whether these changes resulted in a higher gain of student scientific literacy by conducting pre/posttesting of scientific literacy for two cohorts: students experiencing the unreformed curriculum and students experiencing the reformed curriculum. Retention of student scientific literacy for each cohort was also assessed 4 months later. At the end of the academic year, scientific literacy gains were significantly higher for students in the reformed curriculum (p = 0.005), with those students having double the scientific literacy gains of the cohort in the unreformed curriculum. Retention of scientific literacy did not differ between the cohorts. PMID:28495933

The Heroes of CRISPR.

PubMed

Lander, Eric S

2016-01-14

Three years ago, scientists reported that CRISPR technology can enable precise and efficient genome editing in living eukaryotic cells. Since then, the method has taken the scientific community by storm, with thousands of labs using it for applications from biomedicine to agriculture. Yet, the preceding 20-year journey--the discovery of a strange microbial repeat sequence; its recognition as an adaptive immune system; its biological characterization; and its repurposing for genome engineering--remains little known. This Perspective aims to fill in this backstory--the history of ideas and the stories of pioneers--and draw lessons about the remarkable ecosystem underlying scientific discovery. Copyright © 2016 Elsevier Inc. All rights reserved.

Final Scientific Report: DE-SC0002194

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seidler, Gerald

We provide the final scientific report for DE-SC0002194. During the term of this grant, 28 publications spanning a variety of topics were addressed under the rubric of advanced x-ray methods and their application to extreme conditions of time-resolution or x-ray intensities. Notable accomplishments include a new observation of XANES features associated with f-shell reconfiguration in lanthanides, size-dependent x-ray heating effects under XFEL illumination conditions, theoretical development of improved treatments of inelastic x-ray scattering for 'warm dense matter' conditions, and several new instrument develop efforts for atomic, molecular, and condensed phase studies in the lab and at major facility lightsources.

Writing a Review Article: A Graduate Level Writing Class

ERIC Educational Resources Information Center

Ogunsolu, Omotola O.; Wang, Jamie C.; Hanson, Kenneth

2018-01-01

Despite the importance of scientific writing in a chemists' professional career, their development as scientific writers is often neglected in undergraduate and graduate curricula. Among the courses that do encourage students to generate written documents like proposals, lab reports, or essays, the scientific community rarely benefits from the…

Evaluation of oral microbiology lab curriculum reform.

PubMed

Nie, Min; Gao, Zhen Y; Wu, Xin Y; Jiang, Chen X; Du, Jia H

2015-12-07

According to the updated concept of oral microbiology, the School of Stomatology, Wuhan University, has carried out oral microbiology teaching reforms during the last 5 years. There was no lab curriculum before 2009 except for a theory course of oral microbiology. The school has implemented an innovative curriculum with oral medicine characteristics to strengthen understanding of knowledge, cultivate students' scientific interest and develop their potential, to cultivate the comprehensive ability of students. This study was designed to evaluate the oral microbiology lab curriculum by analyzing student performance and perceptions regarding the curriculum from 2009 to 2013. The lab curriculum adopted modalities for cooperative learning. Students collected dental plaque from each other and isolated the cariogenic bacteria with selective medium plates. Then they purified the enrichment culture medium and identified the cariogenic strains by Gram stain and biochemical tests. Both quantitative and qualitative data for 5 years were analysed in this study. Part One of the current study assessed student performance in the lab from 2009 to 2013. Part Two used qualitative means to assess students' perceptions by an open questionnaire. The 271 study students' grades on oral microbiology improved during the lab curriculum: "A" grades rose from 60.5 to 81.2 %, and "C" grades fell from 28.4 to 6.3 %. All students considered the lab curriculum to be interesting and helpful. Quantitative and qualitative data converge to suggest that the lab curriculum has strengthened students' grasp of important microbiology-related theory, cultivated their scientific interest, and developed their potential and comprehensive abilities. Our student performance and perception data support the continued use of the innovative teaching system. As an extension and complement of the theory course, the oral microbiology lab curriculum appears to improve the quality of oral medicine education and help to cultivate high-quality innovative medical talents.

Development of an Open Source, Air-Deployable Weather Station

NASA Astrophysics Data System (ADS)

Krejci, A.; Lopez Alcala, J. M.; Nelke, M.; Wagner, J.; Udell, C.; Higgins, C. W.; Selker, J. S.

2017-12-01

We created a packaged weather station intended to be deployed in the air on tethered systems. The device incorporates lightweight sensors and parts and runs for up to 24 hours off of lithium polymer batteries, allowing the entire package to be supported by a thin fiber. As the fiber does not provide a stable platform, additional data (pitch and roll) from typical weather parameters (e.g. temperature, pressure, humidity, wind speed, and wind direction) are determined using an embedded inertial motion unit. All designs are open sourced including electronics, CAD drawings, and descriptions of assembly and can be found on the OPEnS lab website at http://www.open-sensing.org/lowcost-weather-station/. The Openly Published Environmental Sensing Lab (OPEnS: Open-Sensing.org) expands the possibilities of scientific observation of our Earth, transforming the technology, methods, and culture by combining open-source development and cutting-edge technology. New OPEnS labs are now being established in India, France, Switzerland, the Netherlands, and Ghana.

How Do You Like Your Science, Wet or Dry? How Two Lab Experiences Influence Student Understanding of Science Concepts and Perceptions of Authentic Scientific Practice.

PubMed

Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W; Levias, Sheldon

2017-01-01

This study examines how two kinds of authentic research experiences related to smoking behavior-genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)-influence students' perceptions and understanding of scientific research and related science concepts. The study used pre and post surveys and a focus group protocol to compare students who conducted the research experiences in one of two sequences: genotyping before database and database before genotyping. Students rated the genotyping experiment to be more like real science than the database experiment, in spite of the fact that they associated more scientific tasks with the database experience than genotyping. Independent of the order of completing the labs, students showed gains in their understanding of science concepts after completion of the two experiences. There was little change in students' attitudes toward science pre to post, as measured by the Scientific Attitude Inventory II. However, on the basis of their responses during focus groups, students developed more sophisticated views about the practices and nature of science after they had completed both research experiences, independent of the order in which they experienced them. © 2017 M. Munn et al. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Challenging the Non-Science Majors with Inquiry-based Laboratory Environmental Geoscience Courses

NASA Astrophysics Data System (ADS)

Humphreys, R. R.; Hall, C.; Colgan, M. W.

2009-12-01

Although there is proven rationale for teaching inquiry-based/problem-based lessons in the undergraduate classroom, very few non-major geoscience course implement these instructional strategies in their laboratory sections. The College of Charleston Department of Geology and Environmental Geosciences has developed an introductory Environmental Geology Laboratory course for undergraduate non-majors, which corrects this traditional methodology. The Environmental Geology lab activities employ an inquiry-based approach, in which the students take control of their own learning; a cooperative learning approach, in which each member of a team is responsible not only for learning what is taught but also for helping their peers learn; and a problem/case study-based learning approach, in which activities are abstracted from a real-life scenario. In these lab sessions, students actively engage in mastering course content and develop essential skills while exploring real-world scenarios through case studies. For example, during the two-week section on Earthquakes, teams of students study the effects of seismic motion on various types of sediments found underlying the Charleston, South Carolina region. Students discover areas where the greatest damage occurred during the 1886 7.4 MM earthquake through a walking tour of downtown Charleston. Extracting information from historical and topographic maps, as well as aerial and satellite imagery provides students with the necessary information to produce an earthquake hazard-zone map of the Charleston Peninsula. These types of exercises and laboratory activities allow the students to utilize scientific reasoning and application of scientific concepts to develop solutions to environmental scenarios, such as volcanic eruptions, coastal, flooding, or landslide hazards, and groundwater contamination. The newly implemented labs began in Fall of 2008 and have been undergoing adaptations throughout the Spring and Fall of 2009. Qualitative data will be gathered and analyzed to show the effectiveness of moving beyond traditional laboratory teaching methods to methods that require and promote deeper learning and retaining of content. Qualitative data will be based upon the engagement of the students, the deeper level of questioning, the engagement of the faculty, among others. The data will be acquired through the use of personal responses and end of course surveys. For the Spring 2009 semester, the department will develop a more quantitative means of assessment by integrating a pre- and post-survey for this course as well as the traditionally-taught introductory course. Acquisition of knowledge and depth of knowledge by the students from both types of courses will be obtained and compared for assessing effectiveness of this teaching strategy in a laboratory setting. This data will encourage the faculty teaching Environmental Geology Labs as well as the standard introductory labs to redesign the remaining lab courses. In addition, the method used here may serve as a model for laboratory courses in other disciplines.

Library-Labs-for-Science Literacy Courses.

ERIC Educational Resources Information Center

Pestel, Beverly C.; Engeldinger, Eugene A.

1992-01-01

Describes two library-lab exercises the authors have incorporated into their college chemistry course. The first exercise introduces students to scientific information and familiarizes them with the tools for accessing it. The second provides a framework for evaluating the reliability of that information and addresses the criteria that should be…

Is This Real Life? Is This Just Fantasy?: Realism and Representations in Learning with Technology

NASA Astrophysics Data System (ADS)

Sauter, Megan Patrice

Students often engage in hands-on activities during science learning; however, financial and practical constraints often limit the availability of these activities. Recent advances in technology have led to increases in the use of simulations and remote labs, which attempt to recreate hands-on science learning via computer. Remote labs and simulations are interesting from a cognitive perspective because they allow for different relations between representations and their referents. Remote labs are unique in that they provide a yoked representation, meaning that the representation of the lab on the computer screen is actually linked to that which it represents: a real scientific device. Simulations merely represent the lab and are not connected to any real scientific devices. However, the type of visual representations used in the lab may modify the effects of the lab technology. The purpose of this dissertation is to examine the relation between representation and technology and its effects of students' psychological experiences using online science labs. Undergraduates participated in two studies that investigated the relation between technology and representation. In the first study, participants performed either a remote lab or a simulation incorporating one of two visual representations, either a static image or a video of the equipment. Although participants in both lab conditions learned, participants in the remote lab condition had more authentic experiences. However, effects were moderated by the realism of the visual representation. Participants who saw a video were more invested and felt the experience was more authentic. In a second study, participants performed a remote lab and either saw the same video as in the first study, an animation, or the video and an animation. Most participants had an authentic experience because both representations evoked strong feelings of presence. However, participants who saw the video were more likely to believe the remote technology was real. Overall, the findings suggest that participants' experiences with technology were shaped by representation. Students had more authentic experiences using the remote lab than the simulation. However, incorporating visual representations that enhance presence made these experiences even more authentic and meaningful than afforded by the technology alone.

INSA Virtual Labs: a new R+D framework for innovative space science and technology

NASA Astrophysics Data System (ADS)

Cardesin Moinelo, Alejandro; Sanchez Portal, Miguel

2012-10-01

The company INSA (Ingeniería y Servicios Aeroespaciales) has given support to ESA Scientific missions for more than 20 years and is one of the main companies present in the European Space Astronomy Centre (ESAC) in Madrid since its creation. INSA personnel at ESAC provide high level technical and scientific support to ESA for all Astronomy and Solar System missions. In order to improve and maintain the scientific and technical competences among the employees, a research group has been created with the name "INSA Virtual Labs". This group coordinates all the R+D activities carried out by INSA personnel at ESAC and aims to establish collaborations and improve synergies with other research groups, institutes and universities. This represents a great means to improve the visibility of these activities towards the scientific community and serves as breeding ground for new innovative ideas and future commercial products.

Value added or misattributed? A multi-institution study on the educational benefit of labs for reinforcing physics content

NASA Astrophysics Data System (ADS)

Holmes, N. G.; Olsen, Jack; Thomas, James L.; Wieman, Carl E.

2017-06-01

Instructional labs are widely seen as a unique, albeit expensive, way to teach scientific content. We measured the effectiveness of introductory lab courses at achieving this educational goal across nine different lab courses at three very different institutions. These institutions and courses encompassed a broad range of student populations and instructional styles. The nine courses studied had two key things in common: the labs aimed to reinforce the content presented in lectures, and the labs were optional. By comparing the performance of students who did and did not take the labs (with careful normalization for selection effects), we found universally and precisely no added value to learning course content from taking the labs as measured by course exam performance. This work should motivate institutions and departments to reexamine the goals and conduct of their lab courses, given their resource-intensive nature. We show why these results make sense when looking at the comparative mental processes of students involved in research and instructional labs, and offer alternative goals and instructional approaches that would make lab courses more educationally valuable.

Valx: A system for extracting and structuring numeric lab test comparison statements from text

PubMed Central

Hao, Tianyong; Liu, Hongfang; Weng, Chunhua

2017-01-01

Objectives To develop an automated method for extracting and structuring numeric lab test comparison statements from text and evaluate the method using clinical trial eligibility criteria text. Methods Leveraging semantic knowledge from the Unified Medical Language System (UMLS) and domain knowledge acquired from the Internet, Valx takes 7 steps to extract and normalize numeric lab test expressions: 1) text preprocessing, 2) numeric, unit, and comparison operator extraction, 3) variable identification using hybrid knowledge, 4) variable - numeric association, 5) context-based association filtering, 6) measurement unit normalization, and 7) heuristic rule-based comparison statements verification. Our reference standard was the consensus-based annotation among three raters for all comparison statements for two variables, i.e., HbA1c and glucose, identified from all of Type 1 and Type 2 diabetes trials in ClinicalTrials.gov. Results The precision, recall, and F-measure for structuring HbA1c comparison statements were 99.6%, 98.1%, 98.8% for Type 1 diabetes trials, and 98.8%, 96.9%, 97.8% for Type 2 Diabetes trials, respectively. The precision, recall, and F-measure for structuring glucose comparison statements were 97.3%, 94.8%, 96.1% for Type 1 diabetes trials, and 92.3%, 92.3%, 92.3% for Type 2 diabetes trials, respectively. Conclusions Valx is effective at extracting and structuring free-text lab test comparison statements in clinical trial summaries. Future studies are warranted to test its generalizability beyond eligibility criteria text. The open-source Valx enables its further evaluation and continued improvement among the collaborative scientific community. PMID:26940748

Pennies and Eggs: Initiation into Inquiry Learning for Preservice Elementary Education Teachers

ERIC Educational Resources Information Center

Wink, Donald J.; Hwang-Choe, Jeong Hye

2008-01-01

Two labs incorporating the Science Writing Heuristic are described that introduce scientific inquiry in a course for preservice students majoring in elementary education. One lab adapts a previously described discovery learning opportunity involving the change in composition and mass of pennies in 1982. The other involves the use of flotation…

Assessing Student Learning in a Virtual Laboratory Environment

ERIC Educational Resources Information Center

Wolf, T.

2010-01-01

Laboratory experience is a key factor in technical and scientific education. Virtual laboratories have been proposed to reduce cost and simplify maintenance of lab facilities while still providing students with access to real systems. It is important to determine if such virtual labs are still effective for student learning. In the assessment of a…

"Probeware" on Increase in Schools' Science Labs

ERIC Educational Resources Information Center

Trotter, Andrew

2008-01-01

Though the term, "probeware" may not be a household word, it has grown more familiar to science educators over the past decade, as a new generation of high-tech instruments for collecting and analyzing data from the physical world have been introduced into school science labs. Today, those tools include digital scientific probes or sensors that…

Busting the Limits of Science Laboratory Economics

ERIC Educational Resources Information Center

Bush, Robert C.

2008-01-01

This article discusses the trend facing today's scientific laboratories: that the more specialized the lab, the more expensive it is, and the less accessible it becomes. Or conversely, the more accessible a lab needs to be, the fewer resources can be dedicated per capita, and the less specialized it becomes. From a numerical standpoint, "real"…

Stepwise Approach to Writing Journal-Style Lab Reports in the Organic Chemistry Course Sequence

ERIC Educational Resources Information Center

Wackerly, Jay Wm.

2018-01-01

An approach is described that gradually transitions second-year organic chemistry students to writing full "The Journal of Organic Chemistry" ("JOC") style lab reports. The primary goal was to introduce students to and build rhetorical skills in scientific and technical writing. This was accomplished by focusing on four main…

Easy Ways to Promote Inquiry in a Laboratory Course: The Power of Student Questions

ERIC Educational Resources Information Center

Polacek, Kelly Myer; Keeling, Elena Levine

2005-01-01

To teach students to think like scientists, the authors modified their laboratory course to include regular opportunities for student practice of inquiry and the scientific process. Their techniques are simple; they can be implemented without rewriting lab manuals, require little additional grading beyond typical lab reports, and are applicable…

Traileka Glacier X-Stack. Final Scientific/Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borkar, Shekhar

2015-09-01

The XStack Traleika Glacier (XSTG) project was a three-year research award for exploring a revolutionary exascale-class machine software framework. The XSTG program, including Intel, UC San Diego, Pacific Northwest National Lab, UIUC, Rice University, Reservoir Labs, ET International, and U. Delaware, had major accomplishments, insights, and products resulting from this three-year effort.

Assessing Inquiry Process Skills in the Lab Using a Fast, Simple, Inexpensive Fermentation Model System

ERIC Educational Resources Information Center

Knabb, Maureen T.; Misquith, Geraldine

2006-01-01

Incorporating inquiry-based learning in the college-level introductory biology laboratory is challenging because the labs serve the dual purpose of providing a hands-on opportunity to explore content while also emphasizing the development of scientific process skills. Time limitations and variations in student preparedness for college further…

Information Literacy in the Lab: Graduate Teaching Experiences in First-Year Biology

ERIC Educational Resources Information Center

Lantz, Catherine

2016-01-01

The author interviewed 10 graduate teaching assistants leading lab sessions for first-year biology about how they introduce students to scientific literature. Qualitative data analysis of the interview transcripts revealed that both first-year students and graduate teaching assistants (many of whom are first-year teachers) struggle with…

Hess Deep Interactive Lab: Exploring the Structure and Formation of the Oceanic Crust through Hands-On Models and Online Tools

NASA Astrophysics Data System (ADS)

Kurtz, N.; Marks, N.; Cooper, S. K.

2014-12-01

Scientific ocean drilling through the International Ocean Discovery Program (IODP) has contributed extensively to our knowledge of Earth systems science. However, many of its methods and discoveries can seem abstract and complicated for students. Collaborations between scientists and educators/artists to create accurate yet engaging demonstrations and activities have been crucial to increasing understanding and stimulating interest in fascinating geological topics. One such collaboration, which came out of Expedition 345 to the Hess Deep Rift, resulted in an interactive lab to explore sampling rocks from the usually inacessible lower oceanic crust, offering an insight into the geological processes that form the structure of the Earth's crust. This Hess Deep Interactive Lab aims to explain several significant discoveries made by oceanic drilling utilizing images of actual thin sections and core samples recovered from IODP expeditions. . Participants can interact with a physical model to learn about the coring and drilling processes, and gain an understanding of seafloor structures. The collaboration of this lab developed as a need to explain fundamental notions of the ocean crust formed at fast-spreading ridges. A complementary interactive online lab can be accessed at www.joidesresolution.org for students to engage further with these concepts. This project explores the relationship between physical and on-line models to further understanding, including what we can learn from the pros and cons of each.

Making the Introductory Meteorology Class Relevant in a Minority Serving Community College

NASA Astrophysics Data System (ADS)

Marchese, P. J.; Tremberger, G.; Bluestone, C.

2008-12-01

Queensborough Community College (QCC), a constituent campus of the City University of New York (CUNY), has modified the introductory Meteorology Class lecture and lab to include active learning activities and discovery based learning. The modules were developed at QCC and other 4 year colleges and designed to introduce basic physical concepts important in meteorology. The modules consisted of either interactive lecture demonstrations or discovery-based activities. The discovery based activities are intended to have students become familiar with scientific investigation. Students engage in formulating hypotheses, developing and carrying out experiments, and analyzing scientific data. These activities differ from traditional lab experiments in that they avoid "cookbook" procedures and emphasize having the students learn about physical concepts by applying the scientific method. During the interactive lecture demonstrations the instructor describes an experiment/phenomenon that is to be demonstrated in class. Students discuss the phenomenon based on their experiences and make a prediction about the outcome. The class then runs the experiment, makes observations, and compares the expected results to the actual outcome. As a result of these activities students in the introductory Meteorology class scored higher in exams questions measuring conceptual understanding, as well as factual knowledge. Lower scoring students demonstrated the greatest benefit, while the better students had little (or no) changes. All students also had higher self-efficacy scores after the intervention, compared to an unmodified class.

The national labs and their future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crease, R.P.

National laboratories of the USA, born with the atomic age and raised to prominence by the need for scientific superiority during the long Cold War, are facing the most critical challenge: how best to support the nation's current need to improve its international competitiveness through superior technology The charge that the national laboratories are [open quotes]Cold War relics[close quotes] that have outlived their usefulness is based on a misunderstanding of their mission, says Robert P. Crease, historian for Brookhaven National laboratory. Three of the labs-Los Alamos, Sandia, and Lawrence Livermore- are weapons laboratories and their missions must change. Oak Ridge,more » Argonne, and Brookhaven laboratories are multipurpose: basic research facilities with a continuing role in the world of science The national laboratory system traces its origins to the Manhattan Project. Over the next half-century, America's national labs grew into part of the most effective scientific establishment in the world, a much-copied model for management of large-scale scientific programs. In the early years, each lab defined a niche in the complex world of reactors, accelerators, and high-energy proton and electron physics. In the 1970s, several labs worked on basic energy sciences to help solve a national energy crisis. Today, the labs are pressured to do more applied research-research to transfer to the private sector and will have to respond by devising more effective ways of coordinating basic and applied research. But, Crease warns, [open quotes]It also will be essential that any commitment to applied research not take place at the cost of reducing the wellspring of basic research from which so much applied research flows. [open quotes]Making a solid and persuasive case for the independent value of basic research, and for their own role in that enterprise, may be the most important task facing the laboratories in their next half-century,[close quotes].« less

The status of the Callio Lab Underground Laboratory in the Pyhäsalmi mine

NASA Astrophysics Data System (ADS)

Joutsenvaara, Jari; Enqvist, Timo; Isoherranen, Ville; Jalas, Panu; Kutuniva, Johanna; Kuusiniemi, Pasi

2017-04-01

We present the structure and the latest technical characteristics of the Callio Lab, the new underground laboratory managing the scientific and other non-mining related operations in the Pyhäsalmi mine in Pyhäjärvi, Finland. The very deep laboratory hall space, called Lab 2 of Callio Lab, was finished in spring 2016 at the depth of 1 430 metres (4 100 m.w.e.). Callio Lab has also other easily accessible (by car or truck) halls for laboratory use, for example at the depths of 440 m, 600 m and 990 m. We also review the current and planned activities related to particle physics, applied sciences, industrial R&D and production.

Utah Virtual Lab: JAVA interactivity for teaching science and statistics on line.

PubMed

Malloy, T E; Jensen, G C

2001-05-01

The Utah on-line Virtual Lab is a JAVA program run dynamically off a database. It is embedded in StatCenter (www.psych.utah.edu/learn/statsampler.html), an on-line collection of tools and text for teaching and learning statistics. Instructors author a statistical virtual reality that simulates theories and data in a specific research focus area by defining independent, predictor, and dependent variables and the relations among them. Students work in an on-line virtual environment to discover the principles of this simulated reality: They go to a library, read theoretical overviews and scientific puzzles, and then go to a lab, design a study, collect and analyze data, and write a report. Each student's design and data analysis decisions are computer-graded and recorded in a database; the written research report can be read by the instructor or by other students in peer groups simulating scientific conventions.

Evaluation of direct-to-consumer low-volume lab tests in healthy adults

PubMed Central

Kidd, Brian A.; Hoffman, Gabriel; Zimmerman, Noah; Li, Li; Morgan, Joseph W.; Glowe, Patricia K.; Botwin, Gregory J.; Parekh, Samir; Babic, Nikolina; Doust, Matthew W.; Stock, Gregory B.; Schadt, Eric E.; Dudley, Joel T.

2016-01-01

BACKGROUND. Clinical laboratory tests are now being prescribed and made directly available to consumers through retail outlets in the USA. Concerns with these test have been raised regarding the uncertainty of testing methods used in these venues and a lack of open, scientific validation of the technical accuracy and clinical equivalency of results obtained through these services. METHODS. We conducted a cohort study of 60 healthy adults to compare the uncertainty and accuracy in 22 common clinical lab tests between one company offering blood tests obtained from finger prick (Theranos) and 2 major clinical testing services that require standard venipuncture draws (Quest and LabCorp). Samples were collected in Phoenix, Arizona, at an ambulatory clinic and at retail outlets with point-of-care services. RESULTS. Theranos flagged tests outside their normal range 1.6× more often than other testing services (P < 0.0001). Of the 22 lab measurements evaluated, 15 (68%) showed significant interservice variability (P < 0.002). We found nonequivalent lipid panel test results between Theranos and other clinical services. Variability in testing services, sample collection times, and subjects markedly influenced lab results. CONCLUSION. While laboratory practice standards exist to control this variability, the disparities between testing services we observed could potentially alter clinical interpretation and health care utilization. Greater transparency and evaluation of testing technologies would increase their utility in personalized health management. FUNDING. This work was supported by the Icahn Institute for Genomics and Multiscale Biology, a gift from the Harris Family Charitable Foundation (to J.T. Dudley), and grants from the NIH (R01 DK098242 and U54 CA189201, to J.T. Dudley, and R01 AG046170 and U01 AI111598, to E.E. Schadt). PMID:27018593

ESIP Lab: Supporting Development of Earth Sciences Cyberinfrastructure through Innovation Commons

NASA Astrophysics Data System (ADS)

Burgess, A. B.; Robinson, E.

2017-12-01

The Earth Science Information Partners (ESIP) is an open, networked community that brings together science, data and information technology practitioners from across sectors. Participation in ESIP is beneficial because it provides an intellectual commons to expose, gather and enhance in-house capabilities in support of an organization's own mandate. Recently, ESIP has begun to explore piloting activities that have worked in the U.S. in other countries as a way to facilitate international collaboration and cross-pollination. The newly formed ESIP Lab realizes the commons concept by providing a virtual place to come up with with new solutions through facilitated ideation, take that idea to a low stakes development environment and potentially fail, but if successful, expose developing technology to domain experts through a technology evaluation process. The Lab does this by supporting and funding solution-oriented projects that have discrete development periods and associated budgets across organizations and agencies. In addition, the Lab provides access to AWS cloud computing resources, travel support, virtual and in-person collaborative platform for distributed groups and exposure to the ESIP community as an expert pool. This cycle of ideation to incubation to evaluation and ultimately adoption or infusion of Earth sciences cyberinfrastructure empowers the scientific community and has spawned a variety of developments like community-led ontology portals, ideas for W3C prov standard improvement and an evaluation framework that pushes technology forward and aides in infusion. The Lab is one of these concepts that could be implemented in other countries and the outputs of the Lab would be shared as a commons and available across traditional borders. This presentation will share the methods and the outcomes of the Lab and seed ideas for adoption internationally.

Measure, Then Show: Grasping Human Evolution Through an Inquiry-Based, Data-driven Hominin Skulls Lab

PubMed Central

Luberda, Michael

2016-01-01

Incomprehension and denial of the theory of evolution among high school students has been observed to also occur when teachers are not equipped to deliver a compelling case also for human evolution based on fossil evidence. This paper assesses the outcomes of a novel inquiry-based paleoanthropology lab teaching human evolution to high-school students. The inquiry-based Be a Paleoanthropologist for a Day lab placed a dozen hominin skulls into the hands of high-school students. Upon measuring three variables of human evolution, students explain what they have observed and discuss findings. In the 2013/14 school year, 11 biology classes in 7 schools in the Greater New Orleans area participated in this lab. The interviewed teacher cohort unanimously agreed that the lab featuring hominin skull replicas and stimulating student inquiry was a pedagogically excellent method of delivering the subject of human evolution. First, the lab’s learning path of transforming facts to data, information to knowledge, and knowledge to acceptance empowered students to themselves execute part of the science that underpins our understanding of deep time hominin evolution. Second, although challenging, the hands-on format of the lab was accessible to high-school students, most of whom were readily able to engage the lab’s scientific process. Third, the lab’s exciting and compelling pedagogy unlocked higher order thinking skills, effectively activating the cognitive, psychomotor and affected learning domains as defined in Bloom’s taxonomy. Lastly, the lab afforded students a formative experience with a high degree of retention and epistemic depth. Further study is warranted to gauge the degree of these effects. PMID:27513927

Basic Scientific Principles of Diving

ERIC Educational Resources Information Center

MacLean, Don

1976-01-01

Described are some of the physical and physiological scientific principles related to diving. The article is written as supplementary information for a teacher and includes suggested activities, a keyed test, and a bibliography. This article complements one on Sea Lab II in the same issue. (MA)

EarthLabs Modules: Engaging Students In Extended, Rigorous Investigations Of The Ocean, Climate and Weather

NASA Astrophysics Data System (ADS)

Manley, J.; Chegwidden, D.; Mote, A. S.; Ledley, T. S.; Lynds, S. E.; Haddad, N.; Ellins, K.

2016-02-01

EarthLabs, envisioned as a national model for high school Earth or Environmental Science lab courses, is adaptable for both undergraduate middle school students. The collection includes ten online modules that combine to feature a global view of our planet as a dynamic, interconnected system, by engaging learners in extended investigations. EarthLabs support state and national guidelines, including the NGSS, for science content. Four modules directly guide students to discover vital aspects of the oceans while five other modules incorporate ocean sciences in order to complete an understanding of Earth's climate system. Students gain a broad perspective on the key role oceans play in fishing industry, droughts, coral reefs, hurricanes, the carbon cycle, as well as life on land and in the seas to drive our changing climate by interacting with scientific research data, manipulating satellite imagery, numerical data, computer visualizations, experiments, and video tutorials. Students explore Earth system processes and build quantitative skills that enable them to objectively evaluate scientific findings for themselves as they move through ordered sequences that guide the learning. As a robust collection, EarthLabs modules engage students in extended, rigorous investigations allowing a deeper understanding of the ocean, climate and weather. This presentation provides an overview of the ten curriculum modules that comprise the EarthLabs collection developed by TERC and found at http://serc.carleton.edu/earthlabs/index.html. Evaluation data on the effectiveness and use in secondary education classrooms will be summarized.

Revealing the Role of Microbes in Controlling Contaminants

ScienceCinema

Williams, Kenneth Hurst

2018-05-11

In Rifle, Colorado, Berkeley Lab earth scientist, Kenneth Hurst Williams, highlights the role subsurface microbial communities can play in controlling the flow of contaminants in groundwater. The DOE Joint Genome Institute is a key collaborator in the research. Williams is Component Lead of Watershed Structure and Controls within Berkeley Lab's Genomes-to-Watershed Scientific Focus Area.

The Children's Lab at Northern State University. Elementary Teachers Moving toward Scientific Literacy.

ERIC Educational Resources Information Center

Knecht, Paul S.

The Children's Lab at Northern State University (South Dakota) is a science concept development laboratory for use by students in a physical science course for preservice elementary teachers. Its function is to develop science content knowledge in preservice elementary teachers, with the ultimate goal of developing science literacy in children.…

Revealing the Role of Microbes in Controlling Contaminants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Kenneth Hurst

2015-04-02

In Rifle, Colorado, Berkeley Lab earth scientist, Kenneth Hurst Williams, highlights the role subsurface microbial communities can play in controlling the flow of contaminants in groundwater. The DOE Joint Genome Institute is a key collaborator in the research. Williams is Component Lead of Watershed Structure and Controls within Berkeley Lab's Genomes-to-Watershed Scientific Focus Area.

Guitars, Keyboards, Strobes, and Motors--From Vibrational Motion to Active Research

ERIC Educational Resources Information Center

Tagg, Randall; Carlson, John; Asadi-Zeydabadi, Masoud; Busley, Brad; Law-Balding, Katie; Juengel, Mattea

2013-01-01

Physics First is offered to ninth graders at high schools in Aurora, CO. A unique new asset of this school system is an embedded research lab called the "Innovation Hyperlab." The goal of the lab is to connect secondary school teaching to ongoing university scientific research, supporting the school district's aim to create opportunities to…

Faraday's Principle and Air Travel in the Introductory Labs

ERIC Educational Resources Information Center

Abdul-Razzaq, Wathiq; Thakur, Saikat Chakraborty

2017-01-01

We all know that we must improve the quality of teaching in science at all levels. Not only physicists but also many students from other areas of study take the introductory physics courses in college. Physics introductory laboratories (labs) can be one of the best tools to help these students understand applications of scientific principles that…

An Introductory Biology Lab that Uses Enzyme Histochemistry to Teach Students about Skeletal Muscle Fiber Types

ERIC Educational Resources Information Center

Sweeney, Lauren J.; Brodfuehrer, Peter D.; Raughley, Beth L.

2004-01-01

One important goal of introductory biology laboratory experiences is to engage students directly in all steps in the process of scientific discovery. Even when laboratory experiences are built on principles discussed in the classroom, students often do not adequately apply this background to interpretation of results they obtain in lab. This…

The thrill of scientific discovery and leadership with my group

PubMed Central

Greco, Valentina

2016-01-01

My group and I feel tremendously honored to be recognized with the 2016 Early Career Life Scientist Award from the American Society for Cell Biology. In this essay I share the scientific questions that my lab has been excitedly pursuing since starting in August 2009 and the leadership behaviors we have adopted that enable our collective scientific productivity. PMID:27799490

Lab Coats or Trench Coats? Detective Sleuthing as an Alternative to Scientifically Based Research in Indigenous Educational Communities

ERIC Educational Resources Information Center

Kaomea, Julie

2013-01-01

Amidst late 19th-century efforts to emphasize modern medicine's transition to a more scientific approach, physicians seeking to represent themselves as scientists began wearing white laboratory coats. Today educational researchers are likewise urged to don metaphorical white coats as scientifically based research is held up as the cure-all for our…

[Establishment of Quality Control System of Nucleic Acid Detection for Ebola Virus in Sierra Leone-China Friendship Biological Safety Laboratory].

PubMed

Wang, Qin; Zhang, Yong; Nie, Kai; Wang, Huanyu; Du, Haijun; Song, Jingdong; Xiao, Kang; Lei, Wenwen; Guo, Jianqiang; Wei, Hejiang; Cai, Kun; Wang, Yanhai; Wu, Jiang; Gerald, Bangura; Kamara, Idrissa Laybohr; Liang, Mifang; Wu, Guizhen; Dong, Xiaoping

2016-03-01

The quality control process throughout the Ebola virus nucleic acid detection in Sierra Leone-China Friendship Biological Safety Laboratory (SLE-CHN Biosafety Lab) was described in detail, in order to comprehensively display the scientific, rigorous, accurate and efficient practice in detection of Ebola virus of first batch detection team in SLE-CHN Biosafety Lab. Firstly, the key points of laboratory quality control system was described, including the managements and organizing, quality control documents and information management, instrument, reagents and supplies, assessment, facilities design and space allocation, laboratory maintenance and biosecurity. Secondly, the application of quality control methods in the whole process of the Ebola virus detection, including before the test, during the test and after the test, was analyzed. The excellent and professional laboratory staffs, the implementation of humanized management are the cornerstone of the success; High-level biological safety protection is the premise for effective quality control and completion of Ebola virus detection tasks. And professional logistics is prerequisite for launching the laboratory diagnosis of Ebola virus. The establishment and running of SLE-CHN Biosafety Lab has landmark significance for the friendship between Sierra Leone and China, and the lab becomes the most important base for Ebola virus laboratory testing in Sierra Leone.

Current state of purification, isolation and analysis of bacteriocins produced by lactic acid bacteria.

PubMed

Kaškonienė, Vilma; Stankevičius, Mantas; Bimbiraitė-Survilienė, Kristina; Naujokaitytė, Gintarė; Šernienė, Loreta; Mulkytė, Kristina; Malakauskas, Mindaugas; Maruška, Audrius

2017-02-01

The scientific interest for the search of natural means of microbial inhibitors has not faded for several years. A search of natural antibiotics, so-called bacteriocins which are produced by lactic acid bacteria (LAB), gains a huge attention of the scientists in the last century, in order to reduce the usage of synthetic food additives. Pure bacteriocins with wide spectra of antibacterial activity are promising among the natural biopreservatives. The usage of bacteriocin(s) producing LAB as starter culture for the fermentation of some food products, in order to increase their shelf-life, when synthetic preservatives are not allowable, is also possible. There are a lot of studies focusing on the isolation of new bacteriocins from traditional fermented food, dairy products and other foods or sometimes even from unusual non-food matrices. Bacteriocins producing bacteria have been isolated from different sources with the different antibacterial activity against food-borne microorganisms. This review covers the classification of bacteriocins, diversity of sources of bacteriocin(s) producing LAB, antibacterial spectra of isolated bacteriocins and analytical methods for the bacteriocin purification and analysis within the last 15 years.

Rescuing Dogs in the Frederick Community | Poster

Cancer.gov

Many Frederick National Lab employees have a favorite cause to which they volunteer a significant amount of time. For Dianna Kelly, IT program manager/scientific program analyst, Office of Scientific Operations, and Courtney Kennedy, associate technical project manager, Business Enterprise Systems, that cause is dog rescue.

Nanomedicine: Problem Solving to Treat Cancer

ERIC Educational Resources Information Center

Hemling, Melissa A.; Sammel, Lauren M.; Zenner, Greta; Payne, Amy C.; Crone, Wendy C.

2006-01-01

Many traditional classroom science and technology activities often ask students to complete prepackaged labs that ensure that everyone arrives at the same "scientifically accurate" solution or theory, which ignores the important problem-solving and creative aspects of scientific research and technological design. Students rarely have the…

Labview Interface Concepts Used in NASA Scientific Investigations and Virtual Instruments

NASA Technical Reports Server (NTRS)

Roth, Don J.; Parker, Bradford H.; Rapchun, David A.; Jones, Hollis H.; Cao, Wei

2001-01-01

This article provides an overview of several software control applications developed for NASA using LabVIEW. The applications covered here include (1) an Ultrasonic Measurement System for nondestructive evaluation of advanced structural materials, an Xray Spectral Mapping System for characterizing the quality and uniformity of developing photon detector materials, (2) a Life Testing System for these same materials, (3) and the instrument panel for an aircraft mounted Cloud Absorption Radiometer that measures the light scattered by clouds in multiple spectral bands. Many of the software interface concepts employed are explained. Panel layout and block diagram (code) strategies for each application are described. In particular, some of the more unique features of the applications' interfaces and source code are highlighted. This article assumes that the reader has a beginner-to-intermediate understanding of LabVIEW methods.

Incorporation of a PbSe Array Based Spectrograph into EPICS using LabView at the JLab FEL Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. Hardy; S.V. Benson; Michelle D. Shinn

2005-08-21

A real-time spectrograph with a 1Hz update rate was designed and installed at the JLab FEL facility using a Cal Sensors PbSe array and a Roper Scientific SpectraPro 300 monochrometer. This paper describes the implementation of EPICS channel access on a remote PC running LabView with modification of vendor supplied LabView VI's to allow display of FEL light spectra in real-time on a remote workstation. This allows PC based diagnostics to be used in EPICS.

Gourmet Lab: The Scientific Principles Behind Your Favorite Foods

ERIC Educational Resources Information Center

Young, Sarah

2011-01-01

Hands-on, inquiry-based, and relevant to every student's life, "Gourmet Lab" serves up a full menu of activities for science teachers of grades 6-12. This collection of 15 hands-on experiments--each of which includes a full set of both student and teacher pages--challenges students to take on the role of scientist and chef, as they boil,…

Bilingual (German-English) Molecular Biology Courses in an Out-of-School Lab on a University Campus: Cognitive and Affective Evaluation

ERIC Educational Resources Information Center

Rodenhauser, Annika; Preisfeld, Angelika

2015-01-01

Taking into account (German) students' deficiencies in scientific literacy as well as reading competence and the "mother tongue + 2" objective of the European commission, a bilingual course on molecular biology was developed. It combines CLIL fundamentals and practical experimentation in an out-of-school lab. Cognitive and affective…

From cookbooks to single sentences: The evolution of my labs

NASA Astrophysics Data System (ADS)

Morrison, Andrew

2014-11-01

Like many physics teachers, I love to have my students spend time working in the laboratory. There is often no better way to test an idea about how the physical world works than to actually set up an experiment and see if the idea can be ruled out or not. This process is an authentic representation of the scientific method, which can take a winding and unpredictable path rather than a clean step-by-step recipe that students want to believe science follows.

What We've Learned about Assessing Hands-On Science.

ERIC Educational Resources Information Center

Shavelson, Richard J.; Baxter, Gail P.

1992-01-01

A recent study compared hands-on scientific inquiry assessment to assessments involving lab notebooks, computer simulations, short-answer paper-and-pencil problems, and multiple-choice questions. Creating high quality performance assessments is a costly, time-consuming process requiring considerable scientific and technological know-how. Improved…

Examining and contrasting the cognitive activities engaged in undergraduate research experiences and lab courses

NASA Astrophysics Data System (ADS)

Holmes, N. G.; Wieman, Carl E.

2016-12-01

While the positive outcomes of undergraduate research experiences (UREs) have been extensively categorized, the mechanisms for those outcomes are less understood. Through lightly structured focus group interviews, we have extracted the cognitive tasks that students identify as engaging in during their UREs. We also use their many comparative statements about their coursework, especially lab courses, to evaluate their experimental physics-related cognitive tasks in those environments. We find there are a number of cognitive tasks consistently encountered in physics UREs that are present in most experimental research. These are seldom encountered in lab or lecture courses, with some notable exceptions. Having time to reflect and fix or revise, and having a sense of autonomy, were both repeatedly cited as key enablers of the benefits of UREs. We also identify tasks encountered in actual experimental research that are not encountered in UREs. We use these findings to identify opportunities for better integration of the cognitive tasks in UREs and lab courses, as well as discussing the barriers that exist. This work responds to extensive calls for science education to better develop students' scientific skills and practices, as well as calls to expose more students to scientific research.

Engaging with science: High school students in summer lab internships

NASA Astrophysics Data System (ADS)

Bequette, Marjorie Bullitt

Years of research and rhetoric have suggested that students should be given the opportunity to work with practicing scientists as a way to develop more sophisticated ideas about the nature of science, yet little research about these experiences exists. This project uses a case study approach to examine the experience of eight high school students working part-time during one summer as research assistants in biomedical laboratories. The students completed small research studies under the supervision of scientist-mentors. This dissertation explores questions related to how these students learned to work in a lab, in what ways they grew to understand this scientific context, and how their own relationships with science changed. The goal of looking at these young adults' summer experiences in science labs is to make suggestions for three settings: programs like this one, where high school students work closely with scientists in lab settings; other programs where scientists and students work together; and science education more generally. Analysis of pre- and post-interviews with students, and extensive observations of their laboratory work, suggests that students develop new ideas about the culture of science and the day-to-day workings of the labs. These ideas hold potential power for the students, and other participants in both similar and different educational settings, as they prepare for lives as scientifically engaged adults.

Valx: A System for Extracting and Structuring Numeric Lab Test Comparison Statements from Text.

PubMed

Hao, Tianyong; Liu, Hongfang; Weng, Chunhua

2016-05-17

To develop an automated method for extracting and structuring numeric lab test comparison statements from text and evaluate the method using clinical trial eligibility criteria text. Leveraging semantic knowledge from the Unified Medical Language System (UMLS) and domain knowledge acquired from the Internet, Valx takes seven steps to extract and normalize numeric lab test expressions: 1) text preprocessing, 2) numeric, unit, and comparison operator extraction, 3) variable identification using hybrid knowledge, 4) variable - numeric association, 5) context-based association filtering, 6) measurement unit normalization, and 7) heuristic rule-based comparison statements verification. Our reference standard was the consensus-based annotation among three raters for all comparison statements for two variables, i.e., HbA1c and glucose, identified from all of Type 1 and Type 2 diabetes trials in ClinicalTrials.gov. The precision, recall, and F-measure for structuring HbA1c comparison statements were 99.6%, 98.1%, 98.8% for Type 1 diabetes trials, and 98.8%, 96.9%, 97.8% for Type 2 diabetes trials, respectively. The precision, recall, and F-measure for structuring glucose comparison statements were 97.3%, 94.8%, 96.1% for Type 1 diabetes trials, and 92.3%, 92.3%, 92.3% for Type 2 diabetes trials, respectively. Valx is effective at extracting and structuring free-text lab test comparison statements in clinical trial summaries. Future studies are warranted to test its generalizability beyond eligibility criteria text. The open-source Valx enables its further evaluation and continued improvement among the collaborative scientific community.

The Updated AGU Ethics Policy: Supporting Inclusive and Diverse Field and Lab Environments within the Geosciences.

NASA Astrophysics Data System (ADS)

Williams, B. M.; McPhaden, M. J.; Gundersen, L. C.

2017-12-01

The American Geophysical Union (AGU), a scientific society of >60,000 members worldwide, has established a set of scientific integrity and professional ethics guidelines for the actions of its members, for the governance of the union in its internal activities, and for the operations and participation in its publications and scientific meetings. More recently AGU has undertaken actions to help address the issue of harassment in the sciences and other work climate issues; and, where applied more broadly as a code of standard behavior, will help address tangential issues of diversity and inclusion. This presentation will highlight the proposed policy changes and additional resources now in place, as they apply to field and lab environments. Progress to date and remaining challenges of this effort will be discussed, including AGU's work to provide additional program strength in the areas of Ethics, Diversity and Inclusion.

Students' perceptions of academic dishonesty in the chemistry classroom laboratory

NASA Astrophysics Data System (ADS)

del Carlo, Dawn I.; Bodner, George M.

2004-01-01

Although the literature on both academic dishonesty and scientific misconduct is extensive, research on academic dishonesty has focused on quizzes, exams, and papers, with the virtual exclusion of the classroom laboratory. This study examined the distinctions undergraduate chemistry majors made between academic dishonesty in the classroom laboratory and scientific misconduct in the research laboratory. Across the spectrum of undergraduate chemistry courses, from the introductory course for first-semester chemistry majors to the capstone course in instrumental analysis, we noted that students believe the classroom lab is fundamentally different from a research or industrial lab. This difference is so significant that it carries over into students' perceptions of dishonesty in these two environments.

In Situ Teaching: Fusing Labs & Lectures in Undergraduate Science Courses to Enhance Immersion in Scientific Research

PubMed Central

Round, Jennifer; Lom, Barbara

2015-01-01

Undergraduate courses in the life sciences at most colleges and universities are traditionally composed of two or three weekly sessions in a classroom supplemented with a weekly three-hour session in a laboratory. We have found that many undergraduates can have difficulty making connections and/or transferring knowledge between lab activities and lecture material. Consequently, we are actively developing ways to decrease the physical and intellectual divides between lecture and lab to help students make more direct links between what they learn in the classroom and what they learn in the lab. In this article we discuss our experiences teaching fused laboratory biology courses that intentionally blurred the distinctions between lab and lecture to provide undergraduates with immersive experiences in science that promote discovery and understanding. PMID:26240531

Improving Scientific Research and Writing Skills through Peer Review and Empirical Group Learning †

PubMed Central

Senkevitch, Emilee; Smith, Ann C.; Marbach-Ad, Gili; Song, Wenxia

2011-01-01

Here we describe a semester-long, multipart activity called “Read and wRite to reveal the Research process” (R3) that was designed to teach students the elements of a scientific research paper. We implemented R3 in an advanced immunology course. In R3, we paralleled the activities of reading, discussion, and presentation of relevant immunology work from primary research papers with student writing, discussion, and presentation of their own lab findings. We used reading, discussing, and writing activities to introduce students to the rationale for basic components of a scientific research paper, the method of composing a scientific paper, and the applications of course content to scientific research. As a final part of R3, students worked collaboratively to construct a Group Research Paper that reported on a hypothesis-driven research project, followed by a peer review activity that mimicked the last stage of the scientific publishing process. Assessment of student learning revealed a statistically significant gain in student performance on writing in the style of a research paper from the start of the semester to the end of the semester. PMID:23653760

Science Outside the Lab: Helping Graduate Students in Science and Engineering Understand the Complexities of Science Policy.

PubMed

Bernstein, Michael J; Reifschneider, Kiera; Bennett, Ira; Wetmore, Jameson M

2017-06-01

Helping scientists and engineers challenge received assumptions about how science, engineering, and society relate is a critical cornerstone for macroethics education. Scientific and engineering research are frequently framed as first steps of a value-free linear model that inexorably leads to societal benefit. Social studies of science and assessments of scientific and engineering research speak to the need for a more critical approach to the noble intentions underlying these assumptions. "Science Outside the Lab" is a program designed to help early-career scientists and engineers understand the complexities of science and engineering policy. Assessment of the program entailed a pre-, post-, and 1 year follow up survey to gauge student perspectives on relationships between science and society, as well as a pre-post concept map exercise to elicit student conceptualizations of science policy. Students leave Science Outside the Lab with greater humility about the role of scientific expertise in science and engineering policy; greater skepticism toward linear notions of scientific advances benefiting society; a deeper, more nuanced understanding of the actors involved in shaping science policy; and a continued appreciation of the contributions of science and engineering to society. The study presents an efficacious program that helps scientists and engineers make inroads into macroethical debates, reframe the ways in which they think about values of science and engineering in society, and more thoughtfully engage with critical mediators of science and society relationships: policy makers and policy processes.

Combining Laboratory Experiments with Digital Tools to Do Scientific Inquiry

ERIC Educational Resources Information Center

Kluge, Anders

2014-01-01

This qualitative study investigates the gap between a lab experiment and theory of science. Two groups of 4 students in 2 different classes in 11th grade (15-16 years old) are followed as they process results and experiences from a lab experiment using a digital environment. The experiment is as a part of a larger project about genes and cells,…

A scientific note on the lactic acid bacterial flora within the honeybee subspecies Apis mellifera (Buckfast), A.m. scutellata, A.m. mellifera, and A.m. monticola

USDA-ARS?s Scientific Manuscript database

It was discovered by Olofsson and Vásquez (2008) that a novel lactic acid bacteria (LAB) microbiota with numerous LAB, comprising the genera Lactobacillus and Bifidobacterium, live in a symbiotic relationship with honeybees (Apis mellifera) in their honey stomach. Previous results from 16S rRNA gene...

Introducing Environmental Toxicology in Instructional Labs: The Use of a Modified Amphibian Developmental Toxicity Assay to Support Inquiry-Based Student Projects

ERIC Educational Resources Information Center

Sauterer, Roger; Rayburn, James R.

2012-01-01

Introducing students to the process of scientific inquiry is a major goal of high school and college labs. Environmental toxins are of great concern and public interest. Modifications of a vertebrate developmental toxicity assay using the frog Xenopus laevis can support student-initiated toxicology experiments that are relevant to humans. Teams of…

Laboratory directed research and development program, FY 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides themore » resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.« less

Data-Oriented Astrophysics at NOAO: The Science Archive & The Data Lab

NASA Astrophysics Data System (ADS)

Juneau, Stephanie; NOAO Data Lab, NOAO Science Archive

2018-06-01

As we keep progressing into an era of increasingly large astronomy datasets, NOAO’s data-oriented mission is growing in prominence. The NOAO Science Archive, which captures and processes the pixel data from mountaintops in Chile and Arizona, now contains holdings at Petabyte scales. Working at the intersection of astronomy and data science, the main goal of the NOAO Data Lab is to provide users with a suite of tools to work close to this data, the catalogs derived from them, as well as externally provided datasets, and thus optimize the scientific productivity of the astronomy community. These tools and services include databases, query tools, virtual storage space, workflows through our Jupyter Notebook server, and scripted analysis. We currently host datasets from NOAO facilities such as the Dark Energy Survey (DES), the DESI imaging Legacy Surveys (LS), the Dark Energy Camera Plane Survey (DECaPS), and the nearly all-sky NOAO Source Catalog (NSC). We are further preparing for large spectroscopy datasets such as DESI. After a brief overview of the Science Archive, the Data Lab and datasets, I will briefly showcase scientific applications showing use of our data holdings. Lastly, I will describe our vision for future developments as we tackle the next technical and scientific challenges.

E-Labs - Learning with Authentic Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bardeen, Marjorie G.; Wayne, Mitchell

the success teachers have had providing an opportunity for students to: • Organize and conduct authentic research. • Experience the environment of scientific collaborations. • Possibly make real contributions to a burgeoning scientific field. We've created projects that are problem-based, student driven and technology dependent. Students reach beyond classroom walls to explore data with other students and experts and share results, publishing original work to a worldwide audience. Students can discover and extend the research of other students, modeling the processes of modern, large-scale research projects. From start to finish e-Labs are student-led, teacher-guided projects. Students need only a Webmore » browser to access computing techniques employed by professional researchers. A Project Map with milestones allows students to set the research plan rather than follow a step-by-step process common in other online projects. Most importantly, e-Labs build the learning experience around the students' own questions and let them use the very tools that scientists use. Students contribute to and access shared data, most derived from professional research databases. They use common analysis tools, store their work and use metadata to discover, replicate and confirm the research of others. This is where real scientific collaboration begins. Using online tools, students correspond with other research groups, post comments and questions, prepare summary reports, and in general participate in the part of scientific research that is often left out of classroom experiments. Teaching tools such as student and teacher logbooks, pre- and post-tests and an assessment rubric aligned with learner outcomes help teachers guide student work. Constraints on interface designs and administrative tools such as registration databases give teachers the "one-stop-shopping" they seek for multiple e-Labs. Teaching and administrative tools also allow us to track usage and assess the impact on student learning.« less

Assessing the development & implementation of a student-centered, "flipped" secondary physics curriculum in which IO-lab digital sensors are issued to students on a 1-to-1 basis

NASA Astrophysics Data System (ADS)

Cunnings, Christopher P.

This teacher-driven, action research dissertation study chronicles the development and implementation of a transformative, two-pronged, student-centered secondary physics education curriculum. From an instructional perspective, the curriculum was situated in the "flipped classroom" teaching approach, which minimizes in-class lecturing and instead predicates classroom learning on collaborative, hands-on, and activity-based lessons. Additionally, all students were issued IO-Lab digital sensors--learning tools developed by professors at the University of Illinois at Urbana-Champaign capable of collecting a vast array of real-time physical data-- on a 1-to-1, 24/7 basis for both in-class and at-home use. In-class, students participated in predominantly activity-based learning, with a sizeable portion of in-class activities incorporating IO-Labs for experimental data collection. Outside of class, students designed real-world research projects using their IO-Labs to study the physics underlying their everyday experiences, and all projects were video recorded, uploaded to YouTube, and then watched in-class to simulate a "mock science conference" in which students provided constructive feedback to each other on their experimental methods and results. The synergistic blending of a) flipped physics instruction, and b) perpetual access to state-of-the-art laboratory equipment, the two prongs forming the basis of this research study, inspired the curriculum title "Flipped IO-Lab," or "F-IO" curriculum. This dissertation study will provide a comprehensive assessment of the benefits and challenges that emerged while designing and implementing the F-IO curriculum from a practitioner's perspective. The assessment of the F-IO curriculum came about through a mixed-methods research methodology during kinematics and dynamics instruction. Specifically, this study includes "Force Concept Inventory" (FCI) pretest/posttest analysis to gauge changes in students' conceptual understanding of physics, as well as "Colorado Learning Attitudes about Science Survey" (CLASS) pre/post data to monitor students' shifts in scientific attitudes throughout the study. The aforementioned pre/post data will be triangulated with field notes and web-based "course opinion survey questions" to provide a comprehensive view of the F-IO curriculum. Significant analysis of the development of the course, as well as the relevant benefits, challenges, and considerations for "flipping" physics instruction, is also contained in this dissertation. The results of the research study include an FCI normalized gain of 0.74 (a "high gain" course), which indicates significant improvement in students' conceptual understanding of Newtonian Mechanics. Additionally, CLASS results indicate significant shifts in student attitudes from generally novice initial scientific perspectives to predominantly expert scientific perspectives by the conclusion of the research study. Of particular interest was students' acknowledgement and appreciation of the real-world implications of what they learned in physics class, as evidenced by CLASS survey data, real-world video challenge projects, and student comments before, during, and after class sessions. However, even despite all of the positive results that emerged throughout the study, a variety of challenges and concerns also materialized with regards to the utilization of F-IO curriculum principles, with the most pronounced being a subset of students whom remained unwilling to embrace web-based and/or flipped instructional teaching methods, preferring instead a more traditional instructional approach. The results and implications of this research study may not only be of interest to physics instructors, but also STEM educators, secondary curriculum designers, digital learning tool designers and researchers, and educational researchers.

FY2014 LBNL LDRD Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ho, Darren

2015-06-01

Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE’s National Laboratory System, Berkeley Lab supports DOE’s missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation. The LDRD program supports Berkeley Lab’s mission in many ways. First, because LDRD funds can be allocated within a relatively short time frame, Berkeley Lab researchers can support the mission of the Department of Energy (DOE) and serve the needs of the nationmore » by quickly responding to forefront scientific problems. Second, LDRD enables Berkeley Lab to attract and retain highly qualified scientists and to support their efforts to carry out worldleading research. In addition, the LDRD program also supports new projects that involve graduate students and postdoctoral fellows, thus contributing to the education mission of Berkeley Lab.« less

Bringing research into a first semester organic chemistry laboratory with the multistep synthesis of carbohydrate-based HIV inhibitor mimics.

PubMed

Pontrello, Jason K

2015-01-01

Benefits of incorporating research experiences into laboratory courses have been well documented, yet examples of research projects designed for the first semester introductory organic chemistry lab course are extremely rare. To address this deficiency, a Carbohydrate-Based human immunodeficiency virus (HIV) Inhibitor project consisting of a synthetic scheme of four reactions was developed for and implemented in the first semester organic lab. Students carried out the synthetic reactions during the last 6 of 10 total labs in the course, generating carbohydrate-based dimeric target molecules modeled after published dimers with application in HIV therapy. The project was designed to provide a research experience through use of literature procedures for reactions performed, exploration of variation in linker length in the target structure, and synthesis of compounds not previously reported in the scientific literature. Project assessment revealed strong student support, indicating enhanced engagement and interest in the course as a direct result of the use of scientific literature and the applications of the synthesized carbohydrate-based molecules. Regardless of discussed challenges in designing a research project for the first semester lab course, the finding from data analysis that a project implemented in the first semester lab had significantly greater student impact than a second semester project should provide motivation for development of additional research projects for a first semester organic course. © 2015 The International Union of Biochemistry and Molecular Biology.

Use of information and communication technologies (ICT) in science education: The views and experiences of three high school teachers

NASA Astrophysics Data System (ADS)

Barreto-Marrero, Luz N.

This case study presents the experiences of three public school chemistry teachers in the transformation of their teaching processes with the use of ICT. The processes' characteristics are documented, what knowledge and skills were learned, and how it changed their organization, planning and teaching. D. H. Jonassen's (1999) ideas on learning strategies for the integration of ICT, from a constructivism and critical thinking perspective guide this study. MacFarlane and Sakellariou's (2002) ideas on the use of ICT in science teaching are also considered. The relationship between ICT, mind tools, learning strategies and teaching methods is studied. The information was collected by semi-structured interviews, classroom observations and document analysis. The results were analyzed according to Wolcott's qualitative analysis model (1994), along with the QRS NVivo (2002) computer program. The teachers learned to use several new ICT equipment and materials that facilitated their teaching and evaluation processes. Among these are the use of lab simulators, various software, CBL sensors, graphic calculators, electronic blackboards, and the Internet. They used teaching strategies for active, authentic, collaborative, constructive and reflective learning according to Jonassen. Their science teaching methods corresponds to the three types, according to MacFarlane and Sakellariou, which fosters scientific method skills and scientific reasoning for science literacy. The teachers, as facilitators and mediators, were inquirers of their students needs; investigators of their curricula, strategists as they organize their teaching skills and methods; experimenters with what they had learned; and collaborators as they fostered cooperative learning. Teachers' developed better lessons, lab exercises and assessment tools, such as rubrics, concept maps, comic strips, and others. They also affirmed that their students demonstrated more motivation, participation, collaboration and learning; developed scientific and technological skills; worked real situations in a collaborative way guided by science standards; and that parents participated in their children's learning. The conditions that facilitated these processes were the availability of technological resources, practical and continuous professional development, colleague communication and collaboration, the paradigmatic change towards constructivism with changes in assessment, school texts, curriculum and educational software, and a new generation of students and teachers open towards ICT, and pre-service teachers with technological skills.

GeneLab: A Systems Biology Platform for Spaceflight Omics Data

NASA Technical Reports Server (NTRS)

Reinsch, Sigrid S.; Lai, San-Huei; Chen, Rick; Thompson, Terri; Berrios, Daniel; Fogle, Homer; Marcu, Oana; Timucin, Linda; Chakravarty, Kaushik; Coughlan, Joseph

2015-01-01

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. Resources to support large numbers of spaceflight investigations are limited. NASA's GeneLab project is maximizing the science output from these experiments by: (1) developing a unique public bioinformatics database that includes space bioscience relevant "omics" data (genomics, transcriptomics, proteomics, and metabolomics) and experimental metadata; (2) partnering with NASA-funded flight experiments through bio-sample sharing or sample augmentation to expedite omics data input to the GeneLab database; and (3) developing community-driven reference flight experiments. The first database, GeneLab Data System Version 1.0, went online in April 2015. V1.0 contains numerous flight datasets and has search and download capabilities. Version 2.0 will be released in 2016 and will link to analytic tools. In 2015 Genelab partnered with two Biological Research in Canisters experiments (BBRIC-19 and BRIC-20) which examine responses of Arabidopsis thaliana to spaceflight. GeneLab also partnered with Rodent Research-1 (RR1), the maiden flight to test the newly developed rodent habitat. GeneLab developed protocols for maxiumum yield of RNA, DNA and protein from precious RR-1 tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected. GeneLab is establishing partnerships with at least three planned flights for 2016. Organism-specific nationwide Science Definition Teams (SDTs) will define future GeneLab dedicated missions and ensure the broader scientific impact of the GeneLab missions. GeneLab ensures prompt release and open access to all high-throughput omics data from spaceflight and ground-based simulations of microgravity and radiation. Overall, GeneLab will facilitate the generation and query of parallel multi-omics data, and deep curation of metadata for integrative analysis, allowing researchers to uncover cellular networks as observed in systems biology platforms. Consequently, the scientific community will have access to a more complete picture of functional and regulatory networks responsive to the spaceflight environment.. Analysis of GeneLab data will contribute fundamental knowledge of how the space environment affects biological systems, and enable emerging terrestrial benefits resulting from mitigation strategies to prevent effects observed during exposure to space. As a result, open access to the data will foster new hypothesis-driven research for future spaceflight studies spanning basic science to translational science.

SEAS Classroom to Sea Labs: New Directions for Ridge 2000 Communitywide Education Outreach

NASA Astrophysics Data System (ADS)

Goehring, L.

2005-12-01

Lessons learned from the two year SEAS pilot program emphasize that student participation in deep-sea research is an important motivator in student learning. Further, SEAS students experience a paradigm shift in understanding evidence-based reasoning and the process of scientific discovery. At the same time, we have learned that fostering authentic student investigations within the confines of the academic year is challenging and only fits classrooms with some academic flexibility. As a result, this year, SEAS will focus on the new Classroom to Sea Lab as a means to help foster student inquiry in the secondary school science classroom. The Classroom to Sea Lab invites student participation in deep-sea research but does so without requiring students to identify and propose suitable sea-going experiments. Classroom to Sea labs are designed to feature current deep-sea research, and emphasize critical skills in laboratory techniques, data collection and analysis, and scientific reporting. Labs are conducted in the classroom (by students) and at sea (by scientists for the students), resulting in parallel datasets for comparison. Labs also feature the work of practicing scientists. An annual Classroom to Sea Report Fair invites students to summarize their findings and submit written analyses for scientist feedback and prizes, emphasizing the importance of communications skills in science. This year, the SEAS program will feature the Shallow-water vs. Deep-sea Vent Mussel Classroom to Sea lab. In this lab, students explore differences in mussel anatomy and feeding strategies, and understand how chemosynthetic symbionts function in this animal. The lab instructs students to dissect shallow-water mussels and measure the proportion of gill tissue to total body tissue. Students are also instructed to download a dataset of vent mussel measurements and compare average proportions. Finally, students are invited to submit their analyses of the lab to the on-line Report Fair sponsored by the Ridge 2000 research community. A primary goal of SEAS is to excite and engage student learners by involving them in actual research in the extreme environments of the deep-sea. The program depends on the contributions of multiple scientists within the Ridge 2000 community. Scientists field student questions during the Ask-a-Scientist email forum, serve as Report Reviewers, are featured in ``Scientist Spotlights,'' host educators during cruises to conduct at-sea portions of a lab, and help develop new labs. It is community involvement that makes the SEAS program possible and so exciting and motivating for students.

Scientific Writing: Strategies and Tools for Students and Advisors

ERIC Educational Resources Information Center

Singh, Vikash; Mayer, Philipp

2014-01-01

Scientific writing is a demanding task and many students need more time than expected to finish their research articles. To speed up the process, we highlight some tools, strategies as well as writing guides. We recommend starting early in the research process with writing and to prepare research articles, not after but in parallel to the lab or…

Confronting Scientific Misconceptions by Fostering a Classroom of Scientists in the Introductory Biology Lab

ERIC Educational Resources Information Center

Holding, Matthew L.; Denton, Robert D.; Kulesza, Amy E.; Ridgway, Judith S.

2014-01-01

A fundamental component of science curricula is the understanding of scientific inquiry. Although recent trends favor using student inquiry to learn concepts through hands-on activities, it is often unclear to students where the line is drawn between the content and the process of science. This activity explicitly introduces students to the…

Developing Students' Scientific Writing and Presentation Skills through Argument Driven Inquiry: An Exploratory Study

ERIC Educational Resources Information Center

C¸etin, Pinar Seda; Eymur, Gülüzar

2017-01-01

In this study, we employed a new instructional model that helps students develop scientific writing and presentation skills. Argument-driven inquiry (ADI) is one of the most novel instructional models that emphasizes the role of argumentation and inquiry in science education equally. This is an exploratory study where five ADI lab activities take…

Board Games and Board Game Design as Learning Tools for Complex Scientific Concepts: Some Experiences

ERIC Educational Resources Information Center

Chiarello, Fabio; Castellano, Maria Gabriella

2016-01-01

In this paper the authors report different experiences in the use of board games as learning tools for complex and abstract scientific concepts such as Quantum Mechanics, Relativity or nano-biotechnologies. In particular we describe "Quantum Race," designed for the introduction of Quantum Mechanical principles, "Lab on a chip,"…

Scientific American Frontiers Teaching Guides for Shows 701-705, October 1996-April 1997.

ERIC Educational Resources Information Center

Connecticut Public Television, Hartford.

These teaching guides are meant to supplement the seventh season (1996-97) of the PBS Series "Scientific American Frontiers". Episode 701 is entitled "Inventing the Future: A Tour of the MIT Media Lab" and the teaching guide contains information and activities on a virtual pet dog, computers of the future, a smart car designed…

Lawrence Berkeley National Laboratory 2015 Annual Financial Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Kim, P

FY2015 financial results reflect a year of significant scientific, operational and financial achievement for Lawrence Berkeley National Laboratory. Complementing many scientific accomplishments, Berkeley Lab completed construction of four new research facilities: the General Purpose Laboratory, Chu Hall, Wang Hall and the Flexlab Building Efficiency Testbed. These state-of-the-art facilities allow for program growth and enhanced collaboration, in part by enabling programs to return to the Lab’s Hill Campus from offsite locations. Detailed planning began for the new Integrative Genomics Building (IGB) that will house another major program currently located offsite. Existing site infrastructure was another key focus area. The Lab prioritizedmore » and increased investments in deferred maintenance in alignment with the Berkeley Lab Infrastructure Plan, which was developed under the leadership of the DOE Office of Science. With the expiration of American Recovery and Reinvestment Act (ARRA) funds, we completed the close-out of all of our 134 ARRA projects, recording total costs of $331M over the FY2009-2015 period. Download the report to read more.« less

Letter to the editor : Impartial review is key.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crabtree, G. W.; Materials Science Division

The News Feature, 'Misconduct in physics: Time to wise up? [Nature 418, 120-121; 2002], raises important issues that the physical-science community must face. Argonne National Laboratory's code of ethics calls for a response very similar to that of Bell Labs, namely: 'The Laboratory director may appoint an ad-hoc scientific review committee to investigate internal or external charges of scientific misconduct, fraud, falsification of data, misinterpretation of data, or other activities involving scientific or technical matters.'

GeoLab: A Geological Workstation for Future Missions

NASA Technical Reports Server (NTRS)

Evans, Cynthia; Calaway, Michael; Bell, Mary Sue; Li, Zheng; Tong, Shuo; Zhong, Ye; Dahiwala, Ravi

2014-01-01

The GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance theThe GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance the early scientific returns from future missions and ensure that the best samples are selected for Earth return. The facility was also designed to foster the development of instrument technology. Since 2009, when GeoLab design and construction began, the GeoLab team [a group of scientists from the Astromaterials Acquisition and Curation Office within the Astromaterials Research and Exploration Science (ARES) Directorate at JSC] has progressively developed and reconfigured the GeoLab hardware and software interfaces and developed test objectives, which were to 1) determine requirements and strategies for sample handling and prioritization for geological operations on other planetary surfaces, 2) assess the scientific contribution of selective in-situ sample characterization for mission planning, operations, and sample prioritization, 3) evaluate analytical instruments and tools for providing efficient and meaningful data in advance of sample return and 4) identify science operations that leverage human presence with robotic tools. In the first year of tests (2010), GeoLab examined basic glovebox operations performed by one and two crewmembers and science operations performed by a remote science team. The 2010 tests also examined the efficacy of basic sample characterization [descriptions, microscopic imagery, X-ray fluorescence (XRF) analyses] and feedback to the science team. In year 2 (2011), the GeoLab team tested enhanced software and interfaces for the crew and science team (including Web-based and mobile device displays) and demonstrated laboratory configurability with a new diagnostic instrument (the Multispectral Microscopic Imager from the JPL and Arizona State University). In year 3 (2012), the GeoLab team installed and tested a robotic sample manipulator and evaluated robotic-human interfaces for science operations.

Fermilab Today - Guidelines

Science.gov Websites

range of story topics, including: Professional achievements and milestones (awards, retirements, records -saving practices at the lab Research milestones, records Scientific research, advances in technology The

Curriculum Alignment with Vision and Change Improves Student Scientific Literacy.

PubMed

Auerbach, Anna Jo; Schussler, Elisabeth E

2017-01-01

The Vision and Change in Undergraduate Biology Education final report challenged institutions to reform their biology courses to focus on process skills and student active learning, among other recommendations. A large southeastern university implemented curricular changes to its majors' introductory biology sequence in alignment with these recommendations. Discussion sections focused on developing student process skills were added to both lectures and a lab, and one semester of lab was removed. This curriculum was implemented using active-learning techniques paired with student collaboration. This study determined whether these changes resulted in a higher gain of student scientific literacy by conducting pre/posttesting of scientific literacy for two cohorts: students experiencing the unreformed curriculum and students experiencing the reformed curriculum. Retention of student scientific literacy for each cohort was also assessed 4 months later. At the end of the academic year, scientific literacy gains were significantly higher for students in the reformed curriculum ( p = 0.005), with those students having double the scientific literacy gains of the cohort in the unreformed curriculum. Retention of scientific literacy did not differ between the cohorts. © 2017 A. J. Auerbach and E. E. Schussler. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Brewing for Students: An Inquiry-Based Microbiology Lab †

PubMed Central

Sato, Brian K.; Alam, Usman; Dacanay, Samantha J.; Lee, Amanda K.; Shaffer, Justin F.

2015-01-01

In an effort to improve and assess student learning, there has been a push to increase the incorporation of discovery-driven modules and those that contain real-world relevance into laboratory curricula. To further this effort, we have developed, implemented, and assessed an undergraduate microbiology laboratory experiment that requires students to use the scientific method while brewing beer. The experiment allows students to brew their own beer and characterize it based on taste, alcohol content, calorie content, pH, and standard reference method. In addition, we assessed whether students were capable of achieving the module learning objectives through a pre-/posttest, student self-evaluation, exam-embedded questions, and an associated worksheet. These objectives included describing the role of the brewing ingredients and predicting how altering the ingredients would affect the characteristics of the beer, amongst others. By completing this experimental module, students accomplished the module objectives, had greater interest in brewing, and were more likely to view beer in scientific terms. Journal of Microbiology & Biology Education PMID:26753030

Brewing for Students: An Inquiry-Based Microbiology Lab.

PubMed

Sato, Brian K; Alam, Usman; Dacanay, Samantha J; Lee, Amanda K; Shaffer, Justin F

2015-12-01

In an effort to improve and assess student learning, there has been a push to increase the incorporation of discovery-driven modules and those that contain real-world relevance into laboratory curricula. To further this effort, we have developed, implemented, and assessed an undergraduate microbiology laboratory experiment that requires students to use the scientific method while brewing beer. The experiment allows students to brew their own beer and characterize it based on taste, alcohol content, calorie content, pH, and standard reference method. In addition, we assessed whether students were capable of achieving the module learning objectives through a pre-/posttest, student self-evaluation, exam-embedded questions, and an associated worksheet. These objectives included describing the role of the brewing ingredients and predicting how altering the ingredients would affect the characteristics of the beer, amongst others. By completing this experimental module, students accomplished the module objectives, had greater interest in brewing, and were more likely to view beer in scientific terms. Journal of Microbiology & Biology Education.

Using Saccharomyces cerevisiae to test the mutagenicity of household compounds: an open ended hypothesis-driven teaching lab.

PubMed

Marshall, Pamela A

2007-01-01

In our Fundamentals of Genetics lab, students perform a wide variety of labs to reinforce and extend the topics covered in lecture. I developed an active-learning lab to augment the lecture topic of mutagenesis. In this lab exercise, students determine if a compound they bring from home is a mutagen. Students are required to read extensive background material, perform research to find a potential mutagen to test, develop a hypothesis, and bring to the lab their own suspected mutagen. This lab uses a specially developed strain of Saccharomyces cerevisiae, D7, to determine if a compound is a mutagen. Mutagenesis of the D7 genome can lead to a scorable alteration in the phenotypes of this strain. Students outline and carry out a protocol for treatment of the yeast tester strain, utilizing the concept of dose/response and positive and negative controls. Students report on their results using a PowerPoint presentation to simulate giving a scientific presentation. The students' self-assessment of their knowledge indicated that, in all cases, the students felt that they knew more about the assay, mutagenesis, and the relationship between genotype and phenotype (P < 0.05) after completing the exercise.

Building 549 Becomes the Backdrop for an Updated Mural | Poster

Cancer.gov

Next time you walk through Building 549 at the National Cancer Institute at Frederick campus, make sure you check out the bright new mural adorning the walls outside the auditorium. A collaboration between the Office of Scientific Operations and Scientific Publications, Graphics and Media, the mural evokes the goals and efforts of the Frederick National Lab and NCI at Frederick.

Building 549 Becomes the Backdrop for an Updated Mural | Poster

Cancer.gov

Next time you walk through Building 549 at the National Cancer Institute at Frederick campus, make sure you check out the bright new mural adorning the walls outside the auditorium. A collaboration between the Office of Scientific Operations and Scientific Publications, Graphics and Media, the mural evokes the goals and efforts of the Frederick National Lab and NCI at

More than a Picture: Helping Undergraduates Learn to Communicate through Scientific Images

PubMed Central

Watson, Fiona L.

2008-01-01

Images are powerful means of communicating scientific results; a strong image can underscore an experimental result more effectively than any words, whereas a poor image can readily undermine a result or conclusion. Developmental biologists rely extensively on images to compare normal versus abnormal development and communicate their results. Most undergraduate lab science courses do not actively teach students skills to communicate effectively through images. To meet this need, we developed a series of image portfolio assignments and imaging workshops in our Developmental Biology course to encourage students to develop communication skills using images. The improvements in their images over the course of the semester were striking, and on anonymous course evaluations, 73% of students listed imaging skills as the most important skill or concept they learned in the course. The image literacy skills acquired through simple lab assignments and in-class workshops appeared to stimulate confidence in the student's own evaluations of current scientific literature to assess research conclusions. In this essay, we discuss our experiences and methodology teaching undergraduates the basic criteria involved in generating images that communicate scientific content and provide a road map for integrating this curriculum into any upper-level biology laboratory course. PMID:18316805

Scientific Analysis and Documentation Provided by EPA Regional Labs

EPA Pesticide Factsheets

The 10 EPA Regional laboratories provide maximum flexibility to support Agency response to natural disasters and emergencies by developing effective approaches for a wide range of analytical challenges.

America Calls

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Born 75 years ago in the Manhattan Project that helped to end World War II, the national lab established at Oak Ridge, Tennessee, still serves national missions in energy, scientific discovery and national security today.

The Fiftieth Anniversary of Brookhaven National Laboratory: A Turbulent Time

NASA Astrophysics Data System (ADS)

Bond, Peter D.

2018-03-01

The fiftieth anniversary year of Brookhaven National Laboratory was momentous, but for reasons other than celebrating its scientific accomplishments. Legacy environmental contamination, community unrest, politics, and internal Department of Energy issues dominated the year. It was the early days of perhaps the most turbulent time in the lab's history. The consequences resulted in significant changes at the lab, but in addition they brought a change to contracts to manage the Department of Energy laboratories.

Multicore: Fallout from a Computing Evolution

ScienceCinema

Yelick, Kathy [Director, NERSC

2017-12-09

July 22, 2008 Berkeley Lab lecture: Parallel computing used to be reserved for big science and engineering projects, but in two years that's all changed. Even laptops and hand-helds use parallel processors. Unfortunately, the software hasn't kept pace. Kathy Yelick, Director of the National Energy Research Scientific Computing Center at Berkeley Lab, describes the resulting chaos and the computing community's efforts to develop exciting applications that take advantage of tens or hundreds of processors on a single chip.

The Fiftieth Anniversary of Brookhaven National Laboratory: A Turbulent Time

NASA Astrophysics Data System (ADS)

Bond, Peter D.

2018-06-01

The fiftieth anniversary year of Brookhaven National Laboratory was momentous, but for reasons other than celebrating its scientific accomplishments. Legacy environmental contamination, community unrest, politics, and internal Department of Energy issues dominated the year. It was the early days of perhaps the most turbulent time in the lab's history. The consequences resulted in significant changes at the lab, but in addition they brought a change to contracts to manage the Department of Energy laboratories.

Human perception testing methodology for evaluating EO/IR imaging systems

NASA Astrophysics Data System (ADS)

Graybeal, John J.; Monfort, Samuel S.; Du Bosq, Todd W.; Familoni, Babajide O.

2018-04-01

The U.S. Army's RDECOM CERDEC Night Vision and Electronic Sensors Directorate (NVESD) Perception Lab is tasked with supporting the development of sensor systems for the U.S. Army by evaluating human performance of emerging technologies. Typical research questions involve detection, recognition and identification as a function of range, blur, noise, spectral band, image processing techniques, image characteristics, and human factors. NVESD's Perception Lab provides an essential bridge between the physics of the imaging systems and the performance of the human operator. In addition to quantifying sensor performance, perception test results can also be used to generate models of human performance and to drive future sensor requirements. The Perception Lab seeks to develop and employ scientifically valid and efficient perception testing procedures within the practical constraints of Army research, including rapid development timelines for critical technologies, unique guidelines for ethical testing of Army personnel, and limited resources. The purpose of this paper is to describe NVESD Perception Lab capabilities, recent methodological improvements designed to align our methodology more closely with scientific best practice, and to discuss goals for future improvements and expanded capabilities. Specifically, we discuss modifying our methodology to improve training, to account for human fatigue, to improve assessments of human performance, and to increase experimental design consultation provided by research psychologists. Ultimately, this paper outlines a template for assessing human perception and overall system performance related to EO/IR imaging systems.

KSC-00pp0846

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is centered over the three-story vacuum chamber in which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0844

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lifted above the three-story vacuum chamber into which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0845

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is moved toward the center over the three-story vacuum chamber in which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0864

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lifted out of the chamber. A rotation and handling fixture holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0844

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lifted above the three-story vacuum chamber into which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0846

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is centered over the three-story vacuum chamber in which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0864

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lifted out of the chamber. A rotation and handling fixture holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0845

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is moved toward the center over the three-story vacuum chamber in which the Lab will be placed. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0865

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, after successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, is lifted up and away from the chamber. A rotation and handling fixture holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0865

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, after successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, is lifted up and away from the chamber. A rotation and handling fixture holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

Evaluation of direct-to-consumer low-volume lab tests in healthy adults.

PubMed

Kidd, Brian A; Hoffman, Gabriel; Zimmerman, Noah; Li, Li; Morgan, Joseph W; Glowe, Patricia K; Botwin, Gregory J; Parekh, Samir; Babic, Nikolina; Doust, Matthew W; Stock, Gregory B; Schadt, Eric E; Dudley, Joel T

2016-05-02

Clinical laboratory tests are now being prescribed and made directly available to consumers through retail outlets in the USA. Concerns with these test have been raised regarding the uncertainty of testing methods used in these venues and a lack of open, scientific validation of the technical accuracy and clinical equivalency of results obtained through these services. We conducted a cohort study of 60 healthy adults to compare the uncertainty and accuracy in 22 common clinical lab tests between one company offering blood tests obtained from finger prick (Theranos) and 2 major clinical testing services that require standard venipuncture draws (Quest and LabCorp). Samples were collected in Phoenix, Arizona, at an ambulatory clinic and at retail outlets with point-of-care services. Theranos flagged tests outside their normal range 1.6× more often than other testing services (P < 0.0001). Of the 22 lab measurements evaluated, 15 (68%) showed significant interservice variability (P < 0.002). We found nonequivalent lipid panel test results between Theranos and other clinical services. Variability in testing services, sample collection times, and subjects markedly influenced lab results. While laboratory practice standards exist to control this variability, the disparities between testing services we observed could potentially alter clinical interpretation and health care utilization. Greater transparency and evaluation of testing technologies would increase their utility in personalized health management. This work was supported by the Icahn Institute for Genomics and Multiscale Biology, a gift from the Harris Family Charitable Foundation (to J.T. Dudley), and grants from the NIH (R01 DK098242 and U54 CA189201, to J.T. Dudley, and R01 AG046170 and U01 AI111598, to E.E. Schadt).

CIDR

Science.gov Websites

CIDR Program Contacts NIH CIDR Program Application Information Barbara Thomas, Ph.D. Scientific Review | Site Map | Get Adobe Reader Subscribe to CIDR News photo of lab tech A Research Technologist examines a

How can we make Science Education and Careers more attractive for Young People?

NASA Astrophysics Data System (ADS)

Knickmeier, K.; Kruse, K.

2016-02-01

The Kiel Science Factory (Kieler Forschungswerkstatt) is a school and teaching laboratory, which breaches the gap between school education and university research. Since opening in October 2012, 3.430 pupils worked at the Kiel Science Factory, and joined the different programs (ocean:lab, nano:lab, geo:lab), the numbers of visitors are increasing. The combination of experts in research and experts in education is very effective to attract young peoplés interest for a scientific career, to communicate science and to increase interest of teachers in current science. The biggest lab is the ocean:lab, it is jointly offered by Kiel University, Cluster of Excellence "Future Ocean" and Leibniz Institute for Science and Mathematics Education at Kiel University (IPN). The ocean:lab is addressing to school classes from grade 3 to 13, and it is strongly involved in pre-service teacher education. Appropriate to their respective level of study, pupils and students get fascinating insights into marine sciences and the working methods of real scientists. Furthermore teacher trainings and summer schools are producing an enthusiasm, which affects as well teachers as their students. The visiting pupils are mainly from Northern Germany, but also from e.g. Austria, Poland and Japan. Topics are the ocean as an ecosystem and how it is affected by anthropogenic impacts. The program offers an integrated investigation of the ecosystem "ocean" (from Plankton to marine mammals) with an interdisciplinary focus on biological aspects and abiotic factors of the habitat. In addition to pollution of the ocean through plastic waste and noise, the effects of climate change and eutrophication plays a role in discussions and tasks. New formats (e.g. an international Citizen Science Project and Expeditionary Learning) are carried out. The developed material is part of expedition boxes, which can be borrowed for project work in schools and science centers. http://www.forschungs-werkstatt.de/

Robert Leland - Associate Lab Director, Scientific Computing and Energy

Science.gov Websites

, applied mathematics, visualization, data, and analysis of energy systems, technologies, policies and Energy Analysis directorate. Leland earned his Ph.D. in mathematics from Oxford University in 1989

Who is at Risk for Down Syndrome?

MedlinePlus

... of the Scientific Director (OSD) Affinity Groups & Labs (AG&L) Scientists Emeriti National Center for Medical Rehabilitation ... at https://www.cdc.gov/ncbddd/birthdefects/downsyndrome/data.html . CDC. (2012). World Down syndrome day . Retrieved ...

"They Sweat for Science": The Harvard Fatigue Laboratory and Self-Experimentation in American Exercise Physiology.

PubMed

Johnson, Andi

2015-08-01

In many scientific fields, the practice of self-experimentation waned over the course of the twentieth century. For exercise physiologists working today, however, the practice of self-experimentation is alive and well. This paper considers the role of the Harvard Fatigue Laboratory and its scientific director, D. Bruce Dill, in legitimizing the practice of self-experimentation in exercise physiology. Descriptions of self-experimentation are drawn from papers published by members of the Harvard Fatigue Lab. Attention is paid to the ethical and practical justifications for self-experimentation in both the lab and the field. Born out of the practical, immediate demands of fatigue protocols, self-experimentation performed the long-term, epistemological function of uniting physiological data across time and space, enabling researchers to contribute to a general human biology program.

KSC00pp0849

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- An overhead crane moves the lid over the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0849

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- An overhead crane moves the lid over the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

A Further Characterization of Empirical Research Related to Learning Outcome Achievement in Remote and Virtual Science Labs

NASA Astrophysics Data System (ADS)

Brinson, James R.

2017-10-01

This paper further characterizes recently reviewed literature related to student learning outcome achievement in non-traditional (virtual and remote) versus traditional (hands-on) science labs, as well as factors to consider when evaluating the state and progress of research in this field as a whole. Current research is characterized according to (1) participant nationality and culture, (2) participant education level, (3) participant demography, (4) scientific discipline, and (5) research methodology, which could provide avenues for further research and useful dialog regarding the measurement and interpretation of data related to student learning outcome achievement in, and thus the efficacy of, non-traditional versus traditional science labs. Current research is also characterized by (6) research publication media and (7) availability of non-traditional labs used, which demonstrate some of the obstacles to progress and consensus in this research field.

LabTrove: A Lightweight, Web Based, Laboratory “Blog” as a Route towards a Marked Up Record of Work in a Bioscience Research Laboratory

PubMed Central

Milsted, Andrew J.; Hale, Jennifer R.; Frey, Jeremy G.; Neylon, Cameron

2013-01-01

Background The electronic laboratory notebook (ELN) has the potential to replace the paper notebook with a marked-up digital record that can be searched and shared. However, it is a challenge to achieve these benefits without losing the usability and flexibility of traditional paper notebooks. We investigate a blog-based platform that addresses the issues associated with the development of a flexible system for recording scientific research. Methodology/Principal Findings We chose a blog-based approach with the journal characteristics of traditional notebooks in mind, recognizing the potential for linking together procedures, materials, samples, observations, data, and analysis reports. We implemented the LabTrove blog system as a server process written in PHP, using a MySQL database to persist posts and other research objects. We incorporated a metadata framework that is both extensible and flexible while promoting consistency and structure where appropriate. Our experience thus far is that LabTrove is capable of providing a successful electronic laboratory recording system. Conclusions/Significance LabTrove implements a one-item one-post system, which enables us to uniquely identify each element of the research record, such as data, samples, and protocols. This unique association between a post and a research element affords advantages for monitoring the use of materials and samples and for inspecting research processes. The combination of the one-item one-post system, consistent metadata, and full-text search provides us with a much more effective record than a paper notebook. The LabTrove approach provides a route towards reconciling the tensions and challenges that lie ahead in working towards the long-term goals for ELNs. LabTrove, an electronic laboratory notebook (ELN) system from the Smart Research Framework, based on a blog-type framework with full access control, facilitates the scientific experimental recording requirements for reproducibility, reuse, repurposing, and redeployment. PMID:23935832

LabTrove: a lightweight, web based, laboratory "blog" as a route towards a marked up record of work in a bioscience research laboratory.

PubMed

Milsted, Andrew J; Hale, Jennifer R; Frey, Jeremy G; Neylon, Cameron

2013-01-01

The electronic laboratory notebook (ELN) has the potential to replace the paper notebook with a marked-up digital record that can be searched and shared. However, it is a challenge to achieve these benefits without losing the usability and flexibility of traditional paper notebooks. We investigate a blog-based platform that addresses the issues associated with the development of a flexible system for recording scientific research. We chose a blog-based approach with the journal characteristics of traditional notebooks in mind, recognizing the potential for linking together procedures, materials, samples, observations, data, and analysis reports. We implemented the LabTrove blog system as a server process written in PHP, using a MySQL database to persist posts and other research objects. We incorporated a metadata framework that is both extensible and flexible while promoting consistency and structure where appropriate. Our experience thus far is that LabTrove is capable of providing a successful electronic laboratory recording system. LabTrove implements a one-item one-post system, which enables us to uniquely identify each element of the research record, such as data, samples, and protocols. This unique association between a post and a research element affords advantages for monitoring the use of materials and samples and for inspecting research processes. The combination of the one-item one-post system, consistent metadata, and full-text search provides us with a much more effective record than a paper notebook. The LabTrove approach provides a route towards reconciling the tensions and challenges that lie ahead in working towards the long-term goals for ELNs. LabTrove, an electronic laboratory notebook (ELN) system from the Smart Research Framework, based on a blog-type framework with full access control, facilitates the scientific experimental recording requirements for reproducibility, reuse, repurposing, and redeployment.

Focusing on the Processes of Science Using Inquiry-oriented Astronomy Labs for Learning Astronomy

NASA Astrophysics Data System (ADS)

Speck, Angela; Ruzhitskaya, L.; Whittington, A.; Witzig, S.

2010-01-01

The U.S. National Science Education Standards provide guidelines for teaching science through inquiry, where students actively develop their understanding of science by combining scientific knowledge with reasoning and thinking skills. Inquiry activities include reading scientific literature, generating hypotheses, designing and carrying out investigations, interpreting data, and formulating conclusions. Inquiry-based instruction emphasizes questions, evidence, and explanation, the essential features of inquiry. We present two projects designed to develop learning materials for laboratory experiences in an undergraduate astronomy course. First, we engage students in inquiry-based learning by using "mini-journal” articles that follow the format of a scientific journal article, including a title, authors, abstract, introduction, methods, results, discussion and citations to peer-reviewed literature. The mini-journal provides a scaffold and serves as a springboard for students to develop and carry out their own follow-up investigation. They then present their findings in the form of their own mini-journal. This mini-journal format more directly reflects and encourages scientific practice. We use this technique in both introductory and upper level courses. The second project develops 3D virtual reality environments to help students interact with scientific constructs, and the use of collaborative learning tools to motivate student activity, deepen understanding and support knowledge building.

Measurement of Scientific Productivity in R&D Sector: Changing paradigm.

PubMed

Kumar, Abhishek; Srivastava, Alpana; Kumar, R P Jeevan; Tiwari, Rajesh K

2017-01-01

Scientific Productivity is a demand of policy makers for a judicious utilization of massive R&D budget allocated and utilized. A huge mass of intellectual assets is employed, which after investing manpower, infrastructure and lab consumables demand for a major outcome which contributes towards building nation's economy. Scientific productivity was only measured through publications or patents. Patents, earmarked as a strong parameter for innovation generation, where, Word Intellectual Property Organisation generated a data on applications for the top 20 offices for patents, where Australia, Brazil and Canada occupied top 3 positions. India ranked 9th with the total patent applications rising from 39762 (2010) to 42854 (2014) i.e. 15%, whereas, it contributes around 2% Patents (innovative productivity) on global scale. Many studies have come forward interestingly within scientific and academic domains in the form of measurement of scientific performance, however, development of productivity indicators and calculation of Scientific Productivity (SP) as a holistic evaluation system is a significant demand. SP, a herculean task is envisaged for productivity analysis and would submit significant factors towards fabricating an effective measurement engine in a holistic manner viable for an individual and organization, being supplementary to each other. This review projects the significance of performance measurement system in R&D through identification and standardization of key parameters. It also includes emphasis on inclusion of standardized parameters, effective for performance measurement which is applicable for scientists, technical staff as well as lab as a facility. This review aims at providing an insight to the evaluators, policy makers, and high level scientific panels to stimulate the scientific intellects on identified indicators so that their work proceeds to generate productive outcome contributing to the economic growth. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

LIB LAB the Library Laboratory: hands-on multimedia science communication

NASA Astrophysics Data System (ADS)

Fillo, Aaron; Niemeyer, Kyle

2017-11-01

Teaching scientific research topics to K-12 audiences in an engaging and meaningful way does not need to be hard; with the right insight and techniques it can be fun to encourage self-guided STEAM (science, technology, engineering, arts, and mathematics) exploration. LIB LAB, short for Library Laboratory, is an educational video series produced by Aaron J. Fillo at Oregon State University in partnership with the Corvallis-Benton County Public Library targeted at K-12 students. Each episode explores a variety of scientific fundamentals with playful experiments and demonstrations. The video lessons are developed using evidence-based practices such as dispelling misconceptions, and language immersion. Each video includes directions for a related experiment that young viewers can conduct at home. In addition, science kits for these at-home experiments are distributed for free to students through the public library network in Benton County, Oregon. This talk will focus on the development of multimedia science education tools and several techniques that scientists can use to engage with a broad audience more effectively. Using examples from the LIB LAB YouTube Channel and collection of hands-on science demonstrations and take-home kits, this talk will present STEAM education in action. Corvallis-Benton County Public Library.

GeoLab 2011: New Instruments and Operations Tested at Desert RATS

NASA Technical Reports Server (NTRS)

Evans, Cindy A.; Calaway, M. J.; Bell, M. S.

2012-01-01

GeoLab is a geological laboratory and testbed designed for supporting geoscience activities during NASA's analog demonstrations. Scientists at NASA's Johnson Space Center built GeoLab as part of a technology project to aid the development of science operational concepts for future planetary surface missions [1, 2, 3]. It is integrated into NASA's Habitat Demonstration Unit, a first generation exploration habitat test article. As a prototype workstation, GeoLab provides a high fidelity working space for analog mission crewmembers to perform in-situ characterization of geologic samples and communicate their findings with supporting scientists. GeoLab analog operations can provide valuable data for assessing the operational and scientific considerations of surface-based geologic analyses such as preliminary examination of samples collected by astronaut crews [4, 5]. Our analog tests also feed into sample handling and advanced curation operational concepts and procedures that will, ultimately, help ensure that the most critical samples are collected during future exploration on a planetary surface, and aid decisions about sample prioritization, sample handling and return. Data from GeoLab operations also supports science planning during a mission by providing additional detailed geologic information to supporting scientists, helping them make informed decisions about strategies for subsequent sample collection opportunities.

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

ScienceCinema

Saxena, Samveg; Shah, Nihar; Hansen, Dana

2018-06-12

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.

Ixion: A Wet-Lab Habitat Platform for Leo and the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Wald, S. I.; Cummins, C. K.; Manber, J.

2018-02-01

Cislunar and LEO habitats derived from launch vehicle upper stages are technically feasible and continues development toward flight. Present station specifications, configurations, and concepts for scientific, exploration, and commercial utilization.

Narragansett, RI Lab--Office of Research and Development

EPA Pesticide Factsheets

The EPA-ORD laboratory in Narragansett, RI is a recognized leader in scientific knowledge and expertise concerning the ecology of oceans, estuaries, and water-sheds, and the effects of human activities on that ecology.

Innovation Across the Federal Government

EPA Pesticide Factsheets

Innovation happens at EPA, but it also takes place at many other government agencies including NASA, DARPA, HHS, OPM, and USGS through projects such as SBIR, innovation labs, innovation offices, and high-risk, high-reward scientific research.

75 FR 57479 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-21

... laboratories. http://cbp.gov/xp/cgov/import/operations-- support/labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America Corporation, as commercial gauger...

Frederick National Lab's Contribution to ATOM | FNLCR Staging

Cancer.gov

As a founding member organization of ATOM, the Frederick National Labwill contribute scientific expertise in precision oncology, computational chemistry and cancer biology, as well as support for open sharing of data sets and predictive modelin

What is vaginal birth after cesarean (VBAC)?

MedlinePlus

... of the Scientific Director (OSD) Affinity Groups & Labs (AG&L) Scientists Emeriti National Center for Medical Rehabilitation ... base (called a low-transverse incision)—the most common type of incision. Note that the incision on ...

U.S. Rep. Dave Weldon outside the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

Standing in front of the U.S. Lab, named Destiny, U.S. Rep. Dave Weldon (left) thanks Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, for briefing him on the equipment inside the Lab. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Introducing computer-assisted training sessions in the clinical skills lab at the Faculty of Medicine, Suez Canal University.

PubMed

Hosny, Somaya; Mishriky, Adel M; Youssef, Mirella

2008-01-01

The Faculty of Medicine, Suez Canal University clinical skills lab was established in 1981 as the first skills lab in Egypt to cope with innovation in medical education adopted since school inauguration in 1978. Students are trained using their peers or models. Training is done weekly, guided by checklists tested for validity and reliability and updated regularly. Students receive immediate feedback on their performance. Recently, the number of students has increased, leading to challenges in providing adequate supervision and training experiences. A project to design and implement a computer-assisted training (CAT) system seemed to be a plausible solution. To assess the quality of a newly developed CAT product, faculty and students' satisfaction with it, and its impact on the learning process. The project involved preparation of multimedia video-films with a web interface for links of different scientific materials. The project was implemented on second year students. A quality check was done to assess the product's scientific content, and technical quality using questionnaires filled by 84 faculty members (139 filled forms) and 175 students (924 filled forms). For assessment of impact, results of examinations after project implementation were compared with results of 2nd year students of previous 3 years. More faculty (96.3%) were satisfied with the product and considered its quality good to excellent, compared to 93.9% of students, p < 0.001. Most faculty (76.2%) have agreed on its suitability for self-learning, while most students considered the product would be suitable after modification. The percentage of students' failures was lower after project implementation, compared to previous 3 years, p < 0.05. CAT materials developed for training of second year students in skills lab proved to be of good scientific content and quality, and suitable for self-learning. Their use was associated with lower failure rates among students. A randomized trial is recommended to ascertain the effectiveness of its application.

KSC00pp0863

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is ready to be removed from the chamber. Workers check a crane being attached to the rotation and handling fixture that holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0863

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is ready to be removed from the chamber. Workers check a crane being attached to the rotation and handling fixture that holds the Lab. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

The U.S. Lab is moved toward the open floor in the O&C Building

NASA Technical Reports Server (NTRS)

2000-01-01

In the Operations and Checkout Building, the U.S. Lab moves overhead toward the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

Quantitative Comparisons to Promote Inquiry in the Introductory Physics Lab

NASA Astrophysics Data System (ADS)

Holmes, N. G.; Bonn, D. A.

2015-09-01

In a recent report, the American Association of Physics Teachers has developed an updated set of recommendations for curriculum of undergraduate physics labs. This document focuses on six major themes: constructing knowledge, modeling, designing experiments, developing technical and practical laboratory skills, analyzing and visualizing data, and communicating physics. These themes all tie together as a set of practical skills in scientific measurement, analysis, and experimentation. In addition to teaching students how to use these skills, it is important for students to know when to use them so that they can use them autonomously. This requires, especially in the case of analytical skills, high levels of inquiry behaviors to reflect on data and iterate measurements, which students rarely do in lab experiments. Often, they perform lab experiments in a plug-and-chug frame, procedurally completing each activity with little to no sensemaking. An emphasis on obtaining true theoretical values or agreement on individual measurements also reinforces inauthentic behaviors such as retroactively inflating measurement uncertainties. This paper aims to offer a relatively simple pedagogical framework for engaging students authentically in experimentation and inquiry in physics labs.

What Are the Risks Factors for Preterm Labor and Birth?

MedlinePlus

... of the Scientific Director (OSD) Affinity Groups & Labs (AG&L) Scientists Emeriti National Center for Medical Rehabilitation ... for Disease Control and Prevention. (2018). Births: Final Data for 2016. Retrieved May 16, 2018, from https:// ...

SU-E-T-157: CARMEN: A MatLab-Based Research Platform for Monte Carlo Treatment Planning (MCTP) and Customized System for Planning Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baeza, J.A.; Ureba, A.; Jimenez-Ortega, E.

Purpose: Although there exist several radiotherapy research platforms, such as: CERR, the most widely used and referenced; SlicerRT, which allows treatment plan comparison from various sources; and MMCTP, a full MCTP system; it is still needed a full MCTP toolset that provides users complete control of calculation grids, interpolation methods and filters in order to “fairly” compare results from different TPSs, supporting verification with experimental measurements. Methods: This work presents CARMEN, a MatLab-based platform including multicore and GPGPU accelerated functions for loading RT data; designing treatment plans; and evaluating dose matrices and experimental data.CARMEN supports anatomic and functional imaging inmore » DICOM format, as well as RTSTRUCT, RTPLAN and RTDOSE. Besides, it contains numerous tools to accomplish the MCTP process, managing egs4phant and phase space files.CARMEN planning mode assist in designing IMRT, VMAT and MERT treatments via both inverse and direct optimization. The evaluation mode contains a comprehensive toolset (e.g. 2D/3D gamma evaluation, difference matrices, profiles, DVH, etc.) to compare datasets from commercial TPS, MC simulations (i.e. 3ddose) and radiochromic film in a user-controlled manner. Results: CARMEN has been validated against commercial RTPs and well-established evaluation tools, showing coherent behavior of its multiple algorithms. Furthermore, CARMEN platform has been used to generate competitive complex treatment that has been published in comparative studies. Conclusion: A new research oriented MCTP platform with a customized validation toolset has been presented. Despite of being coded with a high-level programming language, CARMEN is agile due to the use of parallel algorithms. The wide-spread use of MatLab provides straightforward access to CARMEN’s algorithms to most researchers. Similarly, our platform can benefit from the MatLab community scientific developments as filters, registration algorithms etc. Finally, CARMEN arises the importance of grid and filtering control in treatment plan comparison.« less

Governing Methods: Policy Innovation Labs, Design and Data Science in the Digital Governance of Education

ERIC Educational Resources Information Center

Williamson, Ben

2015-01-01

Policy innovation labs are emerging knowledge actors and technical experts in the governing of education. The article offers a historical and conceptual account of the organisational form of the policy innovation lab. Policy innovation labs are characterised by specific methods and techniques of design, data science, and digitisation in public…

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saxena, Samveg; Shah, Nihar; Hansen, Dana

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates formore » consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.« less

78 FR 70855 - Technical Corrections Relating to the Procedures for the Production or Disclosure of Information...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

..., 2000. LSS provides CBP with forensic and scientific analysis in trade enforcement. The field laboratories use mobile labs to provide on- site emergency response and analysis at the border. \\2\\ CBP...

75 FR 70936 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America...

75 FR 70935 - Accreditation and Approval of Inspectorate America Corporation, as a Commercial Gauger and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Inspectorate America...

Big Machines and Big Science: 80 Years of Accelerators at Stanford

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loew, Gregory

2008-12-16

Longtime SLAC physicist Greg Loew will present a trip through SLAC's origins, highlighting its scientific achievements, and provide a glimpse of the lab's future in 'Big Machines and Big Science: 80 Years of Accelerators at Stanford.'

Assessing and Addressing Students' Scientific Literacy Needs in Physical Geology

NASA Astrophysics Data System (ADS)

Campbell-Stone, E. A.; Myers, J. D.

2005-12-01

Exacting excellence equally from university students around the globe can be accomplished by providing all students with necessary background tools to achieve mastery of their courses, even if those tools are not part of normal content. As instructors we hope to see our students grasp the substance of our courses, make mental connections between course material and practical applications, and use this knowledge to make informed decisions as citizens. Yet many educators have found that students enter university-level introductory courses in mathematics, science and engineering without adequate academic preparation. As part of a FIPSE-funded project at the University of Wyoming, the instructors of the Physical Geology course have taken a new approach to tackling the problem of lack of scientific/mathematic skills in incoming students. Instead of assuming that students should already know or will learn these skills on their own, they assess students' needs and provide them the opportunity to master scientific literacies as they learn geologic content. In the introductory geology course, instructors identified two categories of literacies, or basic skills that are necessary for academic success and citizen participation. Fundamental literacies include performing simple quantitative calculations, making qualitative assessments, and reading and analyzing tables and graphs. Technical literacies are those specific to understanding geology, and comprise the ability to read maps, visualize changes through time, and conceptualize in three dimensions. Because these skills are most easily taught in lab, the in-house lab manual was rewritten to be both literacy- and content-based. Early labs include simple exercises addressing literacies in the context of geological science, and each subsequent lab repeats exposure to literacies, but at increasing levels of difficulty. Resources available to assist students with literacy mastery include individual instruction, a detailed appendix to the lab manual explaining simple tasks such as converting units, and web-based resources. To document the progress of this program, students take pre- and post-course surveys assessing their grasp of the literacies. The surveys gather data on demographics, background, level of interest, level of confidence, understanding, and willingness to complete additional problem sets. This information has been integral in identifying areas of greatest weakness, least interest, and in gauging how backgrounds, expectations, and students' confidence affect their performance.

Computer-based Astronomy Labs for Non-science Majors

NASA Astrophysics Data System (ADS)

Smith, A. B. E.; Murray, S. D.; Ward, R. A.

1998-12-01

We describe and demonstrate two laboratory exercises, Kepler's Third Law and Stellar Structure, which are being developed for use in an astronomy laboratory class aimed at non-science majors. The labs run with Microsoft's Excel 98 (Macintosh) or Excel 97 (Windows). They can be run in a classroom setting or in an independent learning environment. The intent of the labs is twofold; first and foremost, students learn the subject matter through a series of informational frames. Next, students enhance their understanding by applying their knowledge in lab procedures, while also gaining familiarity with the use and power of a widely-used software package and scientific tool. No mathematical knowledge beyond basic algebra is required to complete the labs or to understand the computations in the spreadsheets, although the students are exposed to the concepts of numerical integration. The labs are contained in Excel workbook files. In the files are multiple spreadsheets, which contain either a frame with information on how to run the lab, material on the subject, or one or more procedures. Excel's VBA macro language is used to automate the labs. The macros are accessed through button interfaces positioned on the spreadsheets. This is done intentionally so that students can focus on learning the subject matter and the basic spreadsheet features without having to learn advanced Excel features all at once. Students open the file and progress through the informational frames to the procedures. After each procedure, student comments and data are automatically recorded in a preformatted Lab Report spreadsheet. Once all procedures have been completed, the student is prompted for a filename in which to save their Lab Report. The lab reports can then be printed or emailed to the instructor. The files will have full worksheet and workbook protection, and will have a "redo" feature at the end of the lab for students who want to repeat a procedure.

Cereal fungal infection, mycotoxins, and lactic acid bacteria mediated bioprotection: from crop farming to cereal products.

PubMed

Oliveira, Pedro M; Zannini, Emanuele; Arendt, Elke K

2014-02-01

Lactic acid bacteria (LAB) metabolites are a reliable alternative for reducing fungal infections pre-/post-harvest with additional advantages for cereal-base products which convene the food market's trend. Grain industrial use is in expansion owing to its applicability in generating functional food. The food market is directed towards functional natural food with clear health benefits for the consumer in detriment to chemical additives. The food market chain is becoming broader and more complex, which presents an ever-growing fungal threat. Toxigenic and spoilage fungi are responsible for numerous diseases and economic losses. Cereal infections may occur in the field or post-processing, along the food chain. Consequently, the investigation of LAB metabolites with antifungal activity has gained prominence in the scientific research community. LAB bioprotection retards the development of fungal diseases in the field and inhibit pathogens and spoilage fungi in food products. In addition to the health safety improvement, LAB metabolites also enhance shelf-life, organoleptic and texture qualities of cereal-base foods. This review presents an overview of the fungal impact through the cereal food chain leading to investigation on LAB antifungal compounds. Applicability of LAB in plant protection and cereal industry is discussed. Specific case studies include Fusarium head blight, malting and baking. Copyright © 2013 Elsevier Ltd. All rights reserved.

Food Safety in the Age of Next Generation Sequencing, Bioinformatics, and Open Data Access.

PubMed

Taboada, Eduardo N; Graham, Morag R; Carriço, João A; Van Domselaar, Gary

2017-01-01

Public health labs and food regulatory agencies globally are embracing whole genome sequencing (WGS) as a revolutionary new method that is positioned to replace numerous existing diagnostic and microbial typing technologies with a single new target: the microbial draft genome. The ability to cheaply generate large amounts of microbial genome sequence data, combined with emerging policies of food regulatory and public health institutions making their microbial sequences increasingly available and public, has served to open up the field to the general scientific community. This open data access policy shift has resulted in a proliferation of data being deposited into sequence repositories and of novel bioinformatics software designed to analyze these vast datasets. There also has been a more recent drive for improved data sharing to achieve more effective global surveillance, public health and food safety. Such developments have heightened the need for enhanced analytical systems in order to process and interpret this new type of data in a timely fashion. In this review we outline the emergence of genomics, bioinformatics and open data in the context of food safety. We also survey major efforts to translate genomics and bioinformatics technologies out of the research lab and into routine use in modern food safety labs. We conclude by discussing the challenges and opportunities that remain, including those expected to play a major role in the future of food safety science.

KSC-00pp0867

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab moves overhead toward the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0850

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- Workers in the Operations and Checkout Building check the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0868

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab is lowered toward the floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0841

NASA Image and Video Library

2000-06-30

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is moved to the vacuum chamber in the Operations and Checkout Building for testing. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

KSC00pp0867

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab moves overhead toward the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0842

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- A worker checks the cable fittings on the U.S. Lab, a component of the International Space Station, before it is lifted and placed inside the vacuum chamber in the Operations and Checkout Building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0862

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is ready to be lifted and removed from the chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0852

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- With the lid of the three-story vacuum chamber in place, a worker on top checks release of the cables. Inside the chamber is the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0843

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lifted off the floor of the Operations and Checkout Building in order to be placed inside the vacuum chamber in the building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0841

NASA Image and Video Library

2000-06-30

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is moved to the vacuum chamber in the Operations and Checkout Building for testing. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

KSC00pp0851

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- A worker in the Operations and Checkout Building checks the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0848

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lowered inside the three-story vacuum chamber in the Operations and Checkout Building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0851

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- A worker in the Operations and Checkout Building checks the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0847

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lowered into a three-story vacuum chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0869

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab is lowered toward the floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0842

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- A worker checks the cable fittings on the U.S. Lab, a component of the International Space Station, before it is lifted and placed inside the vacuum chamber in the Operations and Checkout Building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0850

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- Workers in the Operations and Checkout Building check the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0848

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lowered inside the three-story vacuum chamber in the Operations and Checkout Building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0862

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- After successfully completing a leak test inside a vacuum chamber in the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is ready to be lifted and removed from the chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0852

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- With the lid of the three-story vacuum chamber in place, a worker on top checks release of the cables. Inside the chamber is the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0866

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab moves overhead after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0843

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- The U.S. Lab, a component of the International Space Station, is lifted off the floor of the Operations and Checkout Building in order to be placed inside the vacuum chamber in the building. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0847

NASA Image and Video Library

2000-07-01

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lowered into a three-story vacuum chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0866

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab moves overhead after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0870

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab reaches the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC00pp0868

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab is lowered toward the floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0869

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab is lowered toward the floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

KSC-00pp0870

NASA Image and Video Library

2000-07-07

KENNEDY SPACE CENTER, FLA. -- In the Operations and Checkout Building, the U.S. Lab reaches the open floor after being lifted out of the vacuum chamber where it was tested for leaks. The test was very successful. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research

Craniux: A LabVIEW-Based Modular Software Framework for Brain-Machine Interface Research

PubMed Central

Degenhart, Alan D.; Kelly, John W.; Ashmore, Robin C.; Collinger, Jennifer L.; Tyler-Kabara, Elizabeth C.; Weber, Douglas J.; Wang, Wei

2011-01-01

This paper presents “Craniux,” an open-access, open-source software framework for brain-machine interface (BMI) research. Developed in LabVIEW, a high-level graphical programming environment, Craniux offers both out-of-the-box functionality and a modular BMI software framework that is easily extendable. Specifically, it allows researchers to take advantage of multiple features inherent to the LabVIEW environment for on-the-fly data visualization, parallel processing, multithreading, and data saving. This paper introduces the basic features and system architecture of Craniux and describes the validation of the system under real-time BMI operation using simulated and real electrocorticographic (ECoG) signals. Our results indicate that Craniux is able to operate consistently in real time, enabling a seamless work flow to achieve brain control of cursor movement. The Craniux software framework is made available to the scientific research community to provide a LabVIEW-based BMI software platform for future BMI research and development. PMID:21687575

Craniux: a LabVIEW-based modular software framework for brain-machine interface research.

PubMed

Degenhart, Alan D; Kelly, John W; Ashmore, Robin C; Collinger, Jennifer L; Tyler-Kabara, Elizabeth C; Weber, Douglas J; Wang, Wei

2011-01-01

This paper presents "Craniux," an open-access, open-source software framework for brain-machine interface (BMI) research. Developed in LabVIEW, a high-level graphical programming environment, Craniux offers both out-of-the-box functionality and a modular BMI software framework that is easily extendable. Specifically, it allows researchers to take advantage of multiple features inherent to the LabVIEW environment for on-the-fly data visualization, parallel processing, multithreading, and data saving. This paper introduces the basic features and system architecture of Craniux and describes the validation of the system under real-time BMI operation using simulated and real electrocorticographic (ECoG) signals. Our results indicate that Craniux is able to operate consistently in real time, enabling a seamless work flow to achieve brain control of cursor movement. The Craniux software framework is made available to the scientific research community to provide a LabVIEW-based BMI software platform for future BMI research and development.

An introductory biology lab that uses enzyme histochemistry to teach students about skeletal muscle fiber types.

PubMed

Sweeney, Lauren J; Brodfuehrer, Peter D; Raughley, Beth L

2004-12-01

One important goal of introductory biology laboratory experiences is to engage students directly in all steps in the process of scientific discovery. Even when laboratory experiences are built on principles discussed in the classroom, students often do not adequately apply this background to interpretation of results they obtain in lab. This disconnect has been described at the level of medical education (4), so it should not be surprising that educators have struggled with this same phenomenon at the undergraduate level. We describe a new introductory biology lab that challenges students to make these connections. The lab utilizes enzyme histochemistry and morphological observations to draw conclusions about the composition of functionally different types of muscle fibers present in skeletal muscle. We report that students were not only successful at making these observations on a specific skeletal muscle, the gastrocnemius of the frog Rana pipiens, but that they were able to connect their results to the principles of fiber type differences that exist in skeletal muscles in all vertebrates.

Design and Deployment of a General Purpose, Open Source LoRa to Wi-Fi Hub and Data Logger

NASA Astrophysics Data System (ADS)

DeBell, T. C.; Udell, C.; Kwon, M.; Selker, J. S.; Lopez Alcala, J. M.

2017-12-01

Methods and technologies facilitating internet connectivity and near-real-time status updates for in site environmental sensor data are of increasing interest in Earth Science. However, Open Source, Do-It-Yourself technologies that enable plug and play functionality for web-connected sensors and devices remain largely inaccessible for typical researchers in our community. The Openly Published Environmental Sensing Lab at Oregon State University (OPEnS Lab) constructed an Open Source 900 MHz Long Range Radio (LoRa) receiver hub with SD card data logger, Ethernet and Wi-Fi shield, and 3D printed enclosure that dynamically uploads transmissions from multiple wirelessly-connected environmental sensing devices. Data transmissions may be received from devices up to 20km away. The hub time-stamps, saves to SD card, and uploads all transmissions to a Google Drive spreadsheet to be accessed in near-real-time by researchers and GeoVisualization applications (such as Arc GIS) for access, visualization, and analysis. This research expands the possibilities of scientific observation of our Earth, transforming the technology, methods, and culture by combining open-source development and cutting edge technology. This poster details our methods and evaluates the application of using 3D printing, Arduino Integrated Development Environment (IDE), Adafruit's Open-Hardware Feather development boards, and the WIZNET5500 Ethernet shield for designing this open-source, general purpose LoRa to Wi-Fi data logger.

A trait based approach to defining valued mentoring qualities

NASA Astrophysics Data System (ADS)

Pendall, E.

2012-12-01

Graduate training in the sciences requires strong personal interactions among faculty, senior lab members and more junior members. Within the lab-group setting we learn to frame problems, to conduct research and to communicate findings. The result is that individual scientists are partly shaped by a few influential mentors. We have all been influenced by special relationships with mentors, and on reflection we may find that certain qualities have been especially influential in our career choices. In this presentation I will discuss favorable mentoring traits as determined from an informal survey of scientists in varying stages of careers and from diverse backgrounds. Respondents addressed questions about traits they value in their mentors in several categories: 1) personal qualities such as approachability, humor and encouragement; background including gender, ethnicity, and family status; 2) scientific qualities including discipline or specialization, perceived stature in discipline, seniority, breadth of perspective, and level of expectations; and 3) community-oriented qualities promoted by mentors, such as encouraging service contributions and peer-mentoring within the lab group. The results will be compared among respondents by gender, ethnicity, stage of career, type of work, and subdiscipline within the broadly defined Biogeoscience community. We hope to contribute to the growing discussion on building a diverse and balanced scientific workforce.

Providing Real Research Opoportunities to Undergraduates

NASA Astrophysics Data System (ADS)

Ragozzine, Darin

2016-01-01

The current approach to undergraduate education focuses on teaching classes which provide the foundational knowledge for more applied experiences such as scientific research. Like most programs, Florida Institute of Technology (Florida Tech or FIT) strongly encourages undergraduate research, but is dominated by content-focused courses (e.g., "Physical Mechanics"). Research-like experiences are generally offered through "lab" classes, but these are almost always reproductions of past experiments: contrived, formulaic, and lacking the "heart" of real (i.e., potentially publishable) scientific research. Real research opportunities 1) provide students with realistic insight into the actual scientific process; 2) excite students far more than end-of-chapter problems; 3) provide context for the importance of learning math, physics, and astrophysics concepts; and 4) allow unique research progress for well-chosen problems. I have provided real research opportunities as an "Exoplanet Lab" component of my Introduction to Space Science (SPS1020) class at Florida Tech, generally taken by first-year majors in our Physics, Astronomy & Astrophysics, Planetary Science, and Astrobiology degree programs. These labs are a hybrid between citizen science (e.g., PlanetHunters) and simultaneously mentoring ~60 undergraduates in similar small research projects. These projects focus on problems that can be understood in the context of the course, but which benefit from "crowdsourcing". Examples include: dividing up the known planetary systems and developing a classification scheme and organizing them into populations (Fall 2013); searching through folded light curves to discover new exoplanets missed by previous pipelines (Fall 2014); and fitting n-body models to all exoplanets with known Transit Timing Variations to estimate planet masses (Fall 2015). The students love the fact that they are doing real potentially publishable research: not many undergraduates can claim to have discovered new exoplanets! Based on these experiences, I will present practical insights into successfully organizing real research opportunities. By employing some of these best practices, we can truly educate students and make scientific progress.

Simulation-Based e-Learning Tools for Science,Engineering, and Technology Education(SimBeLT)

NASA Astrophysics Data System (ADS)

Davis, Doyle V.; Cherner, Y.

2006-12-01

The focus of Project SimBeLT is the research, development, testing, and dissemination of a new type of simulation-based integrated e-learning set of modules for two-year college technical and engineering curricula in the areas of thermodynamics, fluid physics, and fiber optics that can also be used in secondary schools and four-year colleges. A collection of sophisticated virtual labs is the core component of the SimBeLT modules. These labs will be designed to enhance the understanding of technical concepts and underlying fundamental principles of these topics, as well as to master certain performance based skills online. SimBeLT software will help educators to meet the National Science Education Standard that "learning science and technology is something that students do, not something that is done to them". A major component of Project SimBeLT is the development of multi-layered technology-oriented virtual labs that realistically mimic workplace-like environments. Dynamic data exchange between simulations will be implemented and links with instant instructional messages and data handling tools will be realized. A second important goal of Project SimBeLT labs is to bridge technical skills and scientific knowledge by enhancing the teaching and learning of specific scientific or engineering subjects. SimBeLT builds upon research and outcomes of interactive teaching strategies and tools developed through prior NSF funding (http://webphysics.nhctc.edu/compact/index.html) (Project SimBeLT is partially supported by a grant from the National Science Foundation DUE-0603277)

New Focus on Replacing Animals in the Lab.

ERIC Educational Resources Information Center

Holden, Constance

1982-01-01

Reviews the pros and cons of using animals or alternatives in scientific research. Such alternatives (as indicated in congressional bill HR 556) include mathematical models, isolated organs, tissue and cell cultures, computer simulations, mechanical models, and "lower" organisms among others. (SK)

75 FR 70936 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

.... http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol] DATES: The accreditation and approval of Intertek USA, Inc., as...

How Many People Are Affected By or Are at Risk for Neural Tube Defects?

MedlinePlus

... of the Scientific Director (OSD) Affinity Groups & Labs (AG&L) Scientists Emeriti National Center for Medical Rehabilitation ... for Disease Control and Prevention. (2011). Spina bifida: Data and statistics. Retrieved May 19, 2012, from http:// ...

Building a Course on Global Sustainability using the grand challenges of Energy-Water-Climate

NASA Astrophysics Data System (ADS)

Myers, J. D.

2012-12-01

GEOL1600: Global Sustainability: Managing the Earth's Resources is a lower division integrated science course at the University of Wyoming that fulfills the university's science requirement. Course content and context has been developed using the grand challenge nexus of energy-water-and climate (EWC). The interconnection of these issues, their social relevance and timeliness has provided a framework that gives students an opportunity to recognize why STEM is relevant to their lives regardless of their ultimate professional career choices. The EWC nexus provides the filter to sieve the course's STEM content. It also provides an ideal mechanism by which the non-STEM perspectives important in grand challenge solutions can be seamlessly incorporated in the course. Through a combination of content and context, the relevance of these issues engage students in their own learning. Development of the course followed the Grand Challenge Scientific Literacy (GCSL) model independently developed by the author and two colleagues at the University of Wyoming. This course model stresses science principles centered on the nature of science (e.g., fundamental premises, habits of mind, critical thinking) and unifying scientific concepts (e.g., methods and tools, experimentation, modeling). Grand challenge principles identify the STEM and non-STEM concepts needed to understand the grand challenges, drawing on multiple STEM and non-STEM disciplines and subjects (i.e., economics, politics, unintended consequences, roles of stakeholders). Using the EWC nexus filter and building on the Grand Challenge Principles, specific content included in the course is selected is that most relevant to understanding the Grand Challenges, thereby stressing content depth over breadth. Because quantitative data and reasoning is critical to effectively evaluating challenge solutions, QR is a component of nearly all class activities, while engineering and technology aspects of grand challenges are explicitly stressed. Running concurrently through the course is a consideration of personal perspectives and their influence on student learning, particularly for controversial subjects. Organizationally, the course consists of three one hour lectures and a two hour lab each week. The lectures are used to introduce content and prepare the knowledge base students need for lab. Complementing traditional lectures are lecture worksheets (short activities applying topics previously presented in lecture) and lecture activities (more involved exercises that present a problem the students need to solve using previously learned scientific content and QR skills and tools). Labs focus on case studies set in global social contexts that are timely and relevant. Labs stress scientific skills (modeling groundwater flow) and also consider political and environmental issues, e.g. developing a policy to manage SO2 emissions from copper smelting. The ideas, concepts, educational materials and content developed in this course have been used as the basis for two Math Science Partnerships that have provided professional development for middle and high school science and math teachers and K-12 social, math and science teachers. These programs have worked with teachers to break down the barriers between disciplines and foster collaborative learning centered on socially relevant grand challenges.

Thermo Scientific Sulfur Dioxide Analyzer Instrument Handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springston, S. R.

The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO2 + hυ1 →SO2 *→SO2 + hυ2 The emitted light is proportional to the concentration of SO2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed to interface with external computers throughmore » the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. BNL has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.« less

Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

editor, Todd C Hansen

2009-02-23

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Berkeley Lab LDRD program also play an important role in leveraging DOE capabilities for national needs. The fundamental scientific research and development conducted in the program advances the skills and technologies of importance to our Work For Others (WFO) sponsors. Among many directions, these include a broad range of health-related science and technology of interest to the National Institutes of Health, breast cancer and accelerator research supported by the Department of Defense, detector technologies that should be useful to the Department of Homeland Security, and particle detection that will be valuable to the Environmental Protection Agency. The Berkeley Lab Laboratory Directed Research and Development Program FY2008 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation, and review.« less

Method-centered digital communities on protocols.io for fast-paced scientific innovation.

PubMed

Kindler, Lori; Stoliartchouk, Alexei; Teytelman, Leonid; Hurwitz, Bonnie L

2016-01-01

The Internet has enabled online social interaction for scientists beyond physical meetings and conferences. Yet despite these innovations in communication, dissemination of methods is often relegated to just academic publishing. Further, these methods remain static, with subsequent advances published elsewhere and unlinked. For communities undergoing fast-paced innovation, researchers need new capabilities to share, obtain feedback, and publish methods at the forefront of scientific development. For example, a renaissance in virology is now underway given the new metagenomic methods to sequence viral DNA directly from an environment. Metagenomics makes it possible to "see" natural viral communities that could not be previously studied through culturing methods. Yet, the knowledge of specialized techniques for the production and analysis of viral metagenomes remains in a subset of labs.  This problem is common to any community using and developing emerging technologies and techniques. We developed new capabilities to create virtual communities in protocols.io, an open access platform, for disseminating protocols and knowledge at the forefront of scientific development. To demonstrate these capabilities, we present a virology community forum called VERVENet. These new features allow virology researchers to share protocols and their annotations and optimizations, connect with the broader virtual community to share knowledge, job postings, conference announcements through a common online forum, and discover the current literature through personalized recommendations to promote discussion of cutting edge research. Virtual communities in protocols.io enhance a researcher's ability to: discuss and share protocols, connect with fellow community members, and learn about new and innovative research in the field.  The web-based software for developing virtual communities is free to use on protocols.io. Data are available through public APIs at protocols.io.

The State of the NIH BRAIN Initiative.

PubMed

Koroshetz, Walter; Gordon, Joshua; Adams, Amy; Beckel-Mitchener, Andrea; Churchill, James; Farber, Gregory; Freund, Michelle; Gnadt, Jim; Hsu, Nina; Langhals, Nicholas; Lisanby, Sarah; Liu, Guoying; Peng, Grace; Ramos, Khara; Steinmetz, Michael; Talley, Edmund; White, Samantha

2018-06-19

The BRAIN Initiative® arose from a grand challenge to "accelerate the development and application of new technologies that will enable researchers to produce dynamic pictures of the brain that show how individual brain cells and complex neural circuits interact at the speed of thought." The BRAIN Initiative is a public-private effort focused on the development and use of powerful tools for acquiring fundamental insights about how information processing occurs in the central nervous system. As the Initiative enters its fifth year, NIH has supported over 500 principal investigators, who have answered the Initiative's challenge via hundreds of publications describing novel tools, methods, and discoveries that address the Initiative's seven scientific priorities. We describe scientific advances produced by individual labs, multi-investigator teams, and entire consortia that, over the coming decades, will produce more comprehensive and dynamic maps of the brain, deepen our understanding of how circuit activity can produce a rich tapestry of behaviors, and lay the foundation for understanding how its circuitry is disrupted in brain disorders. Much more work remains to bring this vision to fruition, and NIH continues to look to the diverse scientific community, from mathematics, to physics, chemistry, engineering, neuroethics, and neuroscience, to ensure that the greatest scientific benefit arises from this unique research Initiative. Copyright © 2018 the authors.

Innovative multi-cantilever array sensor system with MOEMS read-out

NASA Astrophysics Data System (ADS)

Ivaldi, F.; Bieniek, T.; Janus, P.; Grabiec, P.; Majstrzyk, W.; Kopiec, D.; Gotszalk, T.

2016-11-01

Cantilever based sensor system are a well-established sensor family exploited in several every-day life applications as well as in high-end research areas. The very high sensitivity of such systems and the possibility to design and functionalize the cantilevers to create purpose built and highly selective sensors have increased the interest of the scientific community and the industry in further exploiting this promising sensors type. Optical deflection detection systems for cantilever sensors provide a reliable, flexible method for reading information from cantilevers with the highest sensitivity. However the need of using multi-cantilever arrays in several fields of application such as medicine, biology or safety related areas, make the optical method less suitable due to its structural complexity. Working in the frame of a the Joint Undertaking project Lab4MEMS II our group proposes a novel and innovative approach to solve this issue, by integrating a Micro-Opto-Electro-Mechanical-System (MOEMS) with dedicated optics, electronics and software with a MOEMS micro-mirror, ultimately developed in the frame of Lab4MEMSII. In this way we are able to present a closely packed, lightweight solution combining the advantages of standard optical read-out systems with the possibility of recording multiple read-outs from large cantilever arrays quasi simultaneously.

Optical Constituents Along a River Mouth and Inlet: Variability and Signature in Remotely Sensed Reflectance, and: Optical Constituents at the Mouth of the Columbia River: Variability and Signature in Remotely Sensed Reflectance

DTIC Science & Technology

2013-09-30

Vision Floc Camera (MVFC), a Sequoia Scientific LISST 100x Type B, an RBR CTD, and two pressure-actuated Niskin bottles. The Niskin bottles were...Eco bb2fl, that measures 3 backscattering at 532 and 650 nm and CDOM fluorescence, a WetLabs WetStar CDOM fluorometer, a Sequoia Scientific flow

Development and in-line validation of a Process Analytical Technology to facilitate the scale up of coating processes.

PubMed

Wirges, M; Funke, A; Serno, P; Knop, K; Kleinebudde, P

2013-05-05

Incorporation of an active pharmaceutical ingredient (API) into the coating layer of film-coated tablets is a method mainly used to formulate fixed-dose combinations. Uniform and precise spray-coating of an API represents a substantial challenge, which could be overcome by applying Raman spectroscopy as process analytical tool. In pharmaceutical industry, Raman spectroscopy is still mainly used as a bench top laboratory analytical method and usually not implemented in the production process. Concerning the application in the production process, a lot of scientific approaches stop at the level of feasibility studies and do not manage the step to production scale and process applications. The present work puts the scale up of an active coating process into focus, which is a step of highest importance during the pharmaceutical development. Active coating experiments were performed at lab and production scale. Using partial least squares (PLS), a multivariate model was constructed by correlating in-line measured Raman spectral data with the coated amount of API. By transferring this model, being implemented for a lab scale process, to a production scale process, the robustness of this analytical method and thus its applicability as a Process Analytical Technology (PAT) tool for the correct endpoint determination in pharmaceutical manufacturing could be shown. Finally, this method was validated according to the European Medicine Agency (EMA) guideline with respect to the special requirements of the applied in-line model development strategy. Copyright © 2013 Elsevier B.V. All rights reserved.

Teaching Cell Biology to Dental Students with a Project-Based Learning Approach.

PubMed

Costa-Silva, Daniela; Côrtes, Juliana A; Bachinski, Rober F; Spiegel, Carolina N; Alves, Gutemberg G

2018-03-01

Although the discipline of cell biology (CB) is part of the curricula of predoctoral dental schools, students often fail to recognize its practical relevance. The aim of this study was to assess the effectiveness of a practical-theoretical project-based course in closing the gaps among CB, scientific research, and dentistry for dental students. A project-based learning course was developed with nine sequential lessons to evaluate 108 undergraduate dental students enrolled in CB classes of a Brazilian school of dentistry during 2013-16. To highlight the relevance of in vitro studies in the preclinical evaluation of dental materials at the cellular level, the students were challenged to complete the process of drafting a protocol and performing a cytocompatibility assay for a bone substitute used in dentistry. Class activities included small group discussions, scientific database search and article presentations, protocol development, lab experimentation, and writing of a final scientific report. A control group of 31 students attended only one laboratory class on the same theme, and the final reports were compared between the two groups. The results showed that the project-based learning students had superior outcomes in acknowledging the relevance of in vitro methods during biocompatibility testing. Moreover, they produced scientifically sound reports with more content on methodological issues, the relationship with dentistry, and the scientific literature than the control group (p<0.05). The project-based learning students also recognized a higher relevance of scientific research and CB to dental practice. These results suggest that a project-based approach can help contextualize scientific research in dental curricula.

The U.S. Lab placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

In the Operations and Checkout Building, the U.S. Lab, a component of the International Space Station, is lowered into a three-story vacuum chamber. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

Kristin Munch | NREL

Science.gov Websites

Information Management System, Materials Research Society Fall Meeting (2013) Photovoltaics Informatics scientific data management, database and data systems design, database clusters, storage systems integration , and distributed data analytics. She has used her experience in laboratory data management systems, lab

Duluth, MN Lab--Office of Research and Development

EPA Pesticide Factsheets

The EPA-ORD laboratory in Duluth, MN is recognized as a leader in advancing sci-entific knowledge and expertise concerning the effects of stressors on the water resources of the Great Lakes, and the impacts of those changes on benefits to people.

75 FR 70934 - U.S. Customs and Border Protection Accreditation and Approval of Intertek USA, Inc., as a...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

...:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Intertek USA, Inc., as commercial gauger...

Douglas J. Arent - Deputy Associate Lab Director, Scientific Computing

Science.gov Websites

Coordinating Lead Author for the 5th Assessment Report of the Intergovernmental Panel on Climate Change (IPCC of Sciences Panel on Limiting the Magnitude of Future Climate Change, and also served on the

TIMESERIESSTREAMING.VI: LabVIEW program for reliable data streaming of large analog time series

NASA Astrophysics Data System (ADS)

Czerwinski, Fabian; Oddershede, Lene B.

2011-02-01

With modern data acquisition devices that work fast and very precise, scientists often face the task of dealing with huge amounts of data. These need to be rapidly processed and stored onto a hard disk. We present a LabVIEW program which reliably streams analog time series of MHz sampling. Its run time has virtually no limitation. We explicitly show how to use the program to extract time series from two experiments: For a photodiode detection system that tracks the position of an optically trapped particle and for a measurement of ionic current through a glass capillary. The program is easy to use and versatile as the input can be any type of analog signal. Also, the data streaming software is simple, highly reliable, and can be easily customized to include, e.g., real-time power spectral analysis and Allan variance noise quantification. Program summaryProgram title: TimeSeriesStreaming.VI Catalogue identifier: AEHT_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEHT_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 250 No. of bytes in distributed program, including test data, etc.: 63 259 Distribution format: tar.gz Programming language: LabVIEW ( http://www.ni.com/labview/) Computer: Any machine running LabVIEW 8.6 or higher Operating system: Windows XP and Windows 7 RAM: 60-360 Mbyte Classification: 3 Nature of problem: For numerous scientific and engineering applications, it is highly desirable to have an efficient, reliable, and flexible program to perform data streaming of time series sampled with high frequencies and possibly for long time intervals. This type of data acquisition often produces very large amounts of data not easily streamed onto a computer hard disk using standard methods. Solution method: This LabVIEW program is developed to directly stream any kind of time series onto a hard disk. Due to optimized timing and usage of computational resources, such as multicores and protocols for memory usage, this program provides extremely reliable data acquisition. In particular, the program is optimized to deal with large amounts of data, e.g., taken with high sampling frequencies and over long time intervals. The program can be easily customized for time series analyses. Restrictions: Only tested in Windows-operating LabVIEW environments, must use TDMS format, acquisition cards must be LabVIEW compatible, driver DAQmx installed. Running time: As desirable: microseconds to hours

Work continues on Destiny, the U.S. Lab module, in the Space Station Processing Facility

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility (SSPF), work continues on the U.S. Lab module, Destiny, which is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the International Space Station. Destiny shares space in the SSPF with the Shuttle Radar Topography Mission (SRTM) and Leonardo, the Multipurpose Logistics Module (MPLM) built by the Agenzia Spaziale Italiana (ASI). The SRTM is targeted for launch on mission STS-99 in September 1999. Leonardo is scheduled to launch on mission STS- 102 in June 2000.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- The U.S. Lab Destiny rests in the payload bay of Space Shuttle Atlantis. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Growing Cutting-edge X-ray Optics

ScienceCinema

Conley, Ray

2018-03-02

Ever imagined that an Xbox controller could help open a window into a world spanning just one billionth of a meter? Brookhaven Lab's Ray Conley grows cutting-edge optics called multilayer Laue lenses (MLL) one atomic layer at a time to focus high-energy x-rays to within a single nanometer. To achieve this focusing feat, Ray uses a massive, custom-built atomic deposition device, an array of computers, and a trusty Xbox controller. These lenses will be deployed at the Lab's National Synchrotron Light Source II, due to begin shining super-bright light on pressing scientific puzzles in 2015.

Development of a Computer-Assisted Instrumentation Curriculum for Physics Students: Using LabVIEW and Arduino Platform

NASA Astrophysics Data System (ADS)

Kuan, Wen-Hsuan; Tseng, Chi-Hung; Chen, Sufen; Wong, Ching-Chang

2016-06-01

We propose an integrated curriculum to establish essential abilities of computer programming for the freshmen of a physics department. The implementation of the graphical-based interfaces from Scratch to LabVIEW then to LabVIEW for Arduino in the curriculum `Computer-Assisted Instrumentation in the Design of Physics Laboratories' brings rigorous algorithm and syntax protocols together with imagination, communication, scientific applications and experimental innovation. The effectiveness of the curriculum was evaluated via statistical analysis of questionnaires, interview responses, the increase in student numbers majoring in physics, and performance in a competition. The results provide quantitative support that the curriculum remove huge barriers to programming which occur in text-based environments, helped students gain knowledge of programming and instrumentation, and increased the students' confidence and motivation to learn physics and computer languages.

Interactive Visual Least Absolutes Method: Comparison with the Least Squares and the Median Methods

ERIC Educational Resources Information Center

Kim, Myung-Hoon; Kim, Michelle S.

2016-01-01

A visual regression analysis using the least absolutes method (LAB) was developed, utilizing an interactive approach of visually minimizing the sum of the absolute deviations (SAB) using a bar graph in Excel; the results agree very well with those obtained from nonvisual LAB using a numerical Solver in Excel. These LAB results were compared with…

Indicators for the use of robotic labs in basic biomedical research: a literature analysis

PubMed Central

2017-01-01

Robotic labs, in which experiments are carried out entirely by robots, have the potential to provide a reproducible and transparent foundation for performing basic biomedical laboratory experiments. In this article, we investigate whether these labs could be applicable in current experimental practice. We do this by text mining 1,628 papers for occurrences of methods that are supported by commercial robotic labs. Using two different concept recognition tools, we find that 86%–89% of the papers have at least one of these methods. This and our other results provide indications that robotic labs can serve as the foundation for performing many lab-based experiments. PMID:29134146

The next generation of data capturing - digital ink for the data stewards of the future

NASA Astrophysics Data System (ADS)

Czerniak, A.; Fleischer, D.; Schirnick, C.

2012-12-01

Data stewardship of the future requires the continuation from an expert driven discipline into a general scientific routine. One solution how this expansion can be done is the use of data management infrastructures already in the student education. Unsurprisingly, well-known drawbacks in terms of data stewardship from the scientific use complicate this expansion into the educational programs. The advantage of educational programs usually based on the application of standard methods is depleted by the general data capturing process at the point of publication or end of project lifetime. Considering student courses as short projects there are no publications and the end of the course exams keep students just like scientists away from data stewardship tasks. The Kiel Data Management Infrastructure brings the data capturing right in the data creation process. With this approach student education courses can be just another use case of data capturing. Smoothing the data capturing process and making use of available technologies drove the Kiel Data Management Infrastructure into a prototype testing of the use of 'digital ink' and the later on possible handwriting recognition. Making the data digitalization as easy as possible without abandoning the standards of paper-based protocols is the use case 'Smart Pens'. This technology fills the gap between the very long-lasting paper protocols and the effort depending digitalization of field and sampling data but it's also robust enough to work with battery powered devices. The combination of the Kiel Data Management Infrastructure with the 'digital ink' technology enables the data capturing from student education to high-end scientific lab work. Valuing educational data equally to scientific lab data is a strong signal to the researchers of the future while their work is recognized all the way from their undergraduate stage to their post-doc position. Students memorize that their data work is not neglected at any time and so they realize that their is no excuse of keeping any data away from the data management infrastructure. The technology of 'digital ink' is a milestone for the data stewardship discipline and fits perfectly into the a lot of gaps between the data creation and the data infrastructure and as long as we do not establish the life long data capturing support for the scientific career we can not complain about reluctant data submissions.

Educational area for learning of optics and technologies: union of open laboratories of ideas, methods and practices (OLIMP)

NASA Astrophysics Data System (ADS)

Ivashchenko, Maksim; Bodrov, Kirill; Tolstoba, Nadezhda

2016-09-01

The paper deals with the concept of creating the union of Open Laboratories of Ideas, Methods and Practices (OLIMP). It describes the structure designed to simplify the relationship, such as business incubators, start-up accelerators, small innovative enterprises, fabrication laboratories and student centers. We consider their advantages and disadvantages for the specific audience of students and enthusiasts who do not have funding for their own projects. The experience of interaction between the Open Laboratories of Ideas, Methods and Practices and the Student Research Laboratory for Optical Engineering shows the relative impact of structures on each other and the value of using such interaction in the learning process. The paper also addresses issues such as: the motivation of students, enthusiasm for the direction the lab participants identify and maintain the initiatives, profiling in the design, scientific, commercial, social sphere.

Easy research data handling with an OpenEarth DataLab for geo-monitoring research

NASA Astrophysics Data System (ADS)

Vanderfeesten, Maurice; van der Kuil, Annemiek; Prinčič, Alenka; den Heijer, Kees; Rombouts, Jeroen

2015-04-01

OpenEarth DataLab is an open source-based collaboration and processing platform to enable streamlined research data management from raw data ingest and transformation to interoperable distribution. It enables geo-scientists to easily synchronise, share, compute and visualise the dynamic and most up-to-date research data, scripts and models in multi-stakeholder geo-monitoring programs. This DataLab is developed by the Research Data Services team of TU Delft Library and 3TU.Datacentrum together with coastal engineers of Delft University of Technology and Deltares. Based on the OpenEarth software stack an environment has been developed to orchestrate numerous geo-related open source software components that can empower researchers and increase the overall research quality by managing research data; enabling automatic and interoperable data workflows between all the components with track & trace, hit & run data transformation processing in cloud infrastructure using MatLab and Python, synchronisation of data and scripts (SVN), and much more. Transformed interoperable data products (KML, NetCDF, PostGIS) can be used by ready-made OpenEarth tools for further analyses and visualisation, and can be distributed via interoperable channels such as THREDDS (OpenDAP) and GeoServer. An example of a successful application of OpenEarth DataLab is the Sand Motor, an innovative method for coastal protection in the Netherlands. The Sand Motor is a huge volume of sand that has been applied along the coast to be spread naturally by wind, waves and currents. Different research disciplines are involved concerned with: weather, waves and currents, sand distribution, water table and water quality, flora and fauna, recreation and management. Researchers share and transform their data in the OpenEarth DataLab, that makes it possible to combine their data and to see influence of different aspects of the coastal protection on their models. During the project the data are available only for the researchers involved. After the project a large part of the data and scripts will be published with DOI in the Data Archive of 3TU.Datacentrum for reuse in new research. For the 83 project members of the Sand Motor, the OpenEarth DataLab is available on www.zandmotordata.nl. The OpenEarth DataLab not only saves time and increases quality, but has the potential to open new frontiers for exploring cross-domain analysis and visualisations, revealing new scientific insights.

Preliminary results of the scientific experiments on the Kosmos-936 biosatellite

NASA Technical Reports Server (NTRS)

1977-01-01

The scientific equipment and experiments on the Kosmos-936 biosatellite are described, including various ground controls and the lab unit for studies at the descent vehicle landing site. Preliminary results are presented of the physiological experiment with rats, biological experiments with drosophila and higher and lower plants, and radiation physics and radiobiology studies for the planning of biological protection on future space flights. The most significant conclusion from the preliminary data is that rats tolerate space flight better with an artificial force of gravity.

Virtual Interactive Classroom: A New Technology for Distance Learning Developed

NASA Technical Reports Server (NTRS)

York, David W.; Babula, Maria

1999-01-01

The Virtual Interactive Classroom (VIC) allows Internet users, specifically students, to remotely control and access data from scientific equipment. This is a significant advantage to school systems that cannot afford experimental equipment, have Internet access, and are seeking to improve science and math scores with current resources. A VIC Development Lab was established at Lewis to demonstrate that scientific equipment can be controlled by remote users over the Internet. Current projects include a wind tunnel, a room camera, a science table, and a microscope.

Subsurface Scenarios: What are We Trying to Model?

EPA Science Inventory

In collaboration with the Lawrence Berkeley National Lab (George Moridis and team),and after a thorough review of the scientific literature and data and interviews with a selection of experts on the topic, a finite number of plausible scenarios were selected for more quantitative...

The Science and Experimental Equipment for the 12 GeV Upgrade of CEBAF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arrington, John; Bernstein, Aron; Brooks, William

2005-01-10

This Conceptual Design Report (CDR) presents the compelling scientific case for upgrading the Continuous Electron Beam Accelerator Facility (CEBAF) at Jefferson Lab to 12 GeV. Such a facility will make profound contributions to the study of hadronic matter.

Old Wine into New Bottles.

ERIC Educational Resources Information Center

Crandall, G. Douglas

1997-01-01

Discusses how traditional lab exercises can be converted into investigative exercises. Describes an exercise on seed germination that has students design their own experiments based on their initial results. Involves students in the scientific process and allows them to experience the joys and disappointments of experimental work. (JRH)

Hooked on Inquiry: History Labs in the Methods Course

ERIC Educational Resources Information Center

Wood, Linda Sargent

2012-01-01

Methods courses provide a rich opportunity to unpack what it means to "learn history by doing history." To help explain what "doing history" means, the author has created history labs to walk teacher candidates through the historical process. Each lab poses a historical problem, requires analysis of primary and secondary…

Mutation-based learning to improve student autonomy and scientific inquiry skills in a large genetics laboratory course.

PubMed

Wu, Jinlu

2013-01-01

Laboratory education can play a vital role in developing a learner's autonomy and scientific inquiry skills. In an innovative, mutation-based learning (MBL) approach, students were instructed to redesign a teacher-designed standard experimental protocol by a "mutation" method in a molecular genetics laboratory course. Students could choose to delete, add, reverse, or replace certain steps of the standard protocol to explore questions of interest to them in a given experimental scenario. They wrote experimental proposals to address their rationales and hypotheses for the "mutations"; conducted experiments in parallel, according to both standard and mutated protocols; and then compared and analyzed results to write individual lab reports. Various autonomy-supportive measures were provided in the entire experimental process. Analyses of student work and feedback suggest that students using the MBL approach 1) spend more time discussing experiments, 2) use more scientific inquiry skills, and 3) find the increased autonomy afforded by MBL more enjoyable than do students following regimented instructions in a conventional "cookbook"-style laboratory. Furthermore, the MBL approach does not incur an obvious increase in labor and financial costs, which makes it feasible for easy adaptation and implementation in a large class.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berry, Max; Lystig, Ted; Beard, Jonathan

Purpose. To compare the learning of endovascular interventional skills by training on pig models versus virtual reality simulators. Methods. Twelve endovascular novices participated in a study consisting of a pig laboratory (P-Lab) and a virtual reality laboratory (VR-Lab). Subjects were stratified by experience and randomized into four training groups. Following 1 hr of didactic instruction, all attempted an iliac artery stenosis (IAS) revascularization in both laboratories. Onsite proctors evaluated performances using task-specific checklists and global rating scales, yielding a Total Score. Participants completed two training sessions of 3 hr each, using their group's assigned method (P-Lab x 2, P-Lab +more » VR-Lab, VR-Lab + P-Lab, or VR-Lab x 2) and were re-evaluated in both laboratories. A panel of two highly experienced interventional radiologists performed assessments from video recordings. ANCOVA analysis of Total Score against years of surgical, interventional radiology (IR) experience and cumulative number of P-Lab or VR-Lab sessions was conducted. Inter-rater reliability (IRR) was determined by comparing proctored scores with the video assessors in only the VR-Lab. Results. VR-Lab sessions improved the VR-Lab Total Score ({beta} 3.029, p = 0.0015) and P-Lab Total Score ({beta} = 1.814, p = 0.0452). P-Lab sessions increased the P-Lab Total Score ({beta} = 4.074, p < 0.0001) but had no effect on the VR-Lab Total Score. In the general statistical model, both P-Lab sessions ({beta} = 2.552, p = 0.0010) and VR-Lab sessions ({beta} 2.435, p = 0.0032) significantly improved Total Score. Neither previous surgical experience nor IR experience predicted Total Score. VR-Lab scores were consistently higher than the P-Lab scores ({delta} = 6.659, p < 0.0001). VR-Lab IRR was substantial (r = 0.649, p < 0.0008). Conclusions. Endovascular skills learned in the virtual environment may be transferable to the real catheterization laboratory as modeled in the P-Lab.« less

A call for virtual experiments: accelerating the scientific process.

PubMed

Cooper, Jonathan; Vik, Jon Olav; Waltemath, Dagmar

2015-01-01

Experimentation is fundamental to the scientific method, whether for exploration, description or explanation. We argue that promoting the reuse of virtual experiments (the in silico analogues of wet-lab or field experiments) would vastly improve the usefulness and relevance of computational models, encouraging critical scrutiny of models and serving as a common language between modellers and experimentalists. We review the benefits of reusable virtual experiments: in specifying, assaying, and comparing the behavioural repertoires of models; as prerequisites for reproducible research; to guide model reuse and composition; and for quality assurance in the translational application of models. A key step towards achieving this is that models and experimental protocols should be represented separately, but annotated so as to facilitate the linking of models to experiments and data. Lastly, we outline how the rigorous, streamlined confrontation between experimental datasets and candidate models would enable a "continuous integration" of biological knowledge, transforming our approach to systems biology. Copyright © 2014 Elsevier Ltd. All rights reserved.

A new background subtraction method for Western blot densitometry band quantification through image analysis software.

PubMed

Gallo-Oller, Gabriel; Ordoñez, Raquel; Dotor, Javier

2018-06-01

Since its first description, Western blot has been widely used in molecular labs. It constitutes a multistep method that allows the detection and/or quantification of proteins from simple to complex protein mixtures. Western blot quantification method constitutes a critical step in order to obtain accurate and reproducible results. Due to the technical knowledge required for densitometry analysis together with the resources availability, standard office scanners are often used for the imaging acquisition of developed Western blot films. Furthermore, the use of semi-quantitative software as ImageJ (Java-based image-processing and analysis software) is clearly increasing in different scientific fields. In this work, we describe the use of office scanner coupled with the ImageJ software together with a new image background subtraction method for accurate Western blot quantification. The proposed method represents an affordable, accurate and reproducible approximation that could be used in the presence of limited resources availability. Copyright © 2018 Elsevier B.V. All rights reserved.

Solving the challenges of data preprocessing, uploading, archiving, retrieval, analysis and visualization for large heterogeneous paleo- and rock magnetic datasets

NASA Astrophysics Data System (ADS)

Minnett, R.; Koppers, A. A.; Tauxe, L.; Constable, C.; Jarboe, N. A.

2011-12-01

The Magnetics Information Consortium (MagIC) provides an archive for the wealth of rock- and paleomagnetic data and interpretations from studies on natural and synthetic samples. As with many fields, most peer-reviewed paleo- and rock magnetic publications only include high level results. However, access to the raw data from which these results were derived is critical for compilation studies and when updating results based on new interpretation and analysis methods. MagIC provides a detailed metadata model with places for everything from raw measurements to their interpretations. Prior to MagIC, these raw data were extremely cumbersome to collect because they mostly existed in a lab's proprietary format on investigator's personal computers or undigitized in field notebooks. MagIC has developed a suite of offline and online tools to enable the paleomagnetic, rock magnetic, and affiliated scientific communities to easily contribute both their previously published data and data supporting an article undergoing peer-review, to retrieve well-annotated published interpretations and raw data, and to analyze and visualize large collections of published data online. Here we present the technology we chose (including VBA in Excel spreadsheets, Python libraries, FastCGI JSON webservices, Oracle procedures, and jQuery user interfaces) and how we implemented it in order to serve the scientific community as seamlessly as possible. These tools are now in use in labs worldwide, have helped archive many valuable legacy studies and datasets, and routinely enable new contributions to the MagIC Database (http://earthref.org/MAGIC/).

Discourse in science communities: Issues of language, authority, and gender in a life sciences laboratory

NASA Astrophysics Data System (ADS)

Conefrey, Theresa Catherine

Government-sponsored and private research initiatives continue to document the underrepresentation of women in the sciences. Despite policy initiatives, women's attrition rates each stage of their scientific careers remain higher than those of their male colleagues. In order to improve retention rates more information is needed about why many drop out or do not succeed as well as they could. While broad sociological studies and statistical surveys offer a valuable overview of institutional practices, in-depth qualitative analyses are needed to complement these large-scale studies. This present study goes behind statistical generalizations about the situation of women in science to explore the actual experience of scientific socialization and professionalization. Beginning with one reason often cited by women who have dropped out of science: "a bad lab experience," I explore through detailed observation in a naturalistic setting what this phrase might actually mean. Using ethnographic and discourse analytic methods, I present a detailed analysis of the discourse patterns in a life sciences laboratory group at a large research university. I show how language accomplishes the work of indexing and constituting social constraints, of maintaining or undermining the hierarchical power dynamics of the laboratory, of shaping members' presentation of self, and of modeling social and professional skills required to "do science." Despite the widespread conviction among scientists that "the mind has no sex," my study details how gender marks many routine interactions in the lab, including an emphasis on competition, a reinforcement of sex-role stereotypes, and a conversational style that is in several respects more compatible with men's than women's forms of talk.

Teaching Astronomy and Computation with Gaia: A New Curriculum for an Extra-curricular High School Program

NASA Astrophysics Data System (ADS)

Schwab, Ellianna; Faherty, Jacqueline K.; Barua, Prachurjya; Cooper, Ellie; Das, Debjani; Simone-Gonzalez, Luna; Sowah, Maxine; Valdez, Laura; BridgeUP: STEM

2018-01-01

BridgeUP: STEM (BridgeUP) is a program at the American Museum of Natural History (AMNH) that seeks to empower women by providing early-career scientists with research fellowships and high-school aged women with instruction in computer science and algorithmic methods. BridgeUP achieves this goal by employing post-baccalaureate women as Helen Fellows, who, in addition to conducting their own scientific research, mentor and teach high school students from the New York City area. The courses, targeted at early high-school students, are designed to teach algorithmic thinking and scientific methodology through the lens of computational science. In this poster we present the new BridgeUP astronomy curriculum created for 9th and 10th grade girls.The astronomy course we present is designed to introduce basic concepts as well as big data manipulation through a guided exploration of Gaia (DR1). Students learn about measuring astronomical distances through hands-on lab experiments illustrating the brightness/distance relationship, angular size calculations of the height of AMNH buildings, and in-depth Hertzsprung-Russell Diagram activities. Throughout these labs, students increase their proficiency in collecting and analyzing data, while learning to build and share code in teams. The students use their new skills to create color-color diagrams of known co-moving clusters (Oh et al. 2017) in the DR1 dataset using Python, Pandas and Matplotlib. We discuss the successes and lessons learned in the first implementation of this curriculum and show the preliminary work of six of the students, who are continuing with computational astronomy research over the current school year.

From Confrontation to Cooperation: 8th International Seminar on Nuclear War

NASA Astrophysics Data System (ADS)

Zichichi, A.; Dardo, M.

1992-09-01

The Table of Contents for the full book PDF is as follows: * OPENING SESSION * A. Zichichi: Opening Statements * R. Nicolosi: Opening Statements * MESSAGES * CONTRIBUTIONS * "The Contribution of the Erice Seminars in East-West-North-South Scientific Relations" * 1. LASER TECHNOLOGY * "Progress in laser technology" * "Progress in laboratory high gain ICF: prospects for the future" * "Applications of laser in metallurgy" * "Laser tissue interactions in medicine and surgery" * "Laser fusion" * "Compact X-ray lasers in the laboratory" * "Alternative method for inertial confinement" * "Laser technology in China" * 2. NUCLEAR AND CHEMICAL SAFETY * "Reactor safety and reactor design" * "Thereotical analysis and numerical modelling of heat transfer and fuel migration in underlying soils and constructive elements of nuclear plants during an accident release from the core" * "How really to attain reactor safely" * "The problem of chemical weapons" * "Long terms genetic effects of nuclear and chemical accidents" * "Features of the brain which are of importance in understanding the mode of operation of toxic substances and of radiation" * "CO2 and ultra safe reactors" * 3. USE OF MISSILES * "How to convert INF technology for peaceful scientific purposes" * "Beating words into plowshares: a proposal for the peaceful uses of retired nuclear warheads" * "Some thoughts on the peaceful use of retired nuclear warheads" * "Status of the HEFEST project" * 4. OZONE * "Status of the ozone layer problem" * 5. CONVENTIONAL AND NUCLEAR FORCE RESTRUCTURING IN EUROPE * 6. CONFLICT AVOIDANCE MODEL * 7. GENERAL DISCUSSION OF THE WORLD LAB PROJECTS * "East-West-North-South Collaboration in Subnuclear Physics" * "Status of the World Lab in the USSR" * CLOSING SESSION

Bureaucratization in Public Research Institutions

ERIC Educational Resources Information Center

Coccia, Mario

2009-01-01

The purpose of this paper is to analyse the nature of bureaucratization within public research bodies and its relationship to scientific performance, focusing on an Italian case-study. The main finding is that the bureaucratization of the research sector has two dimensions: public research labs have academic bureaucratization since researchers…

Interdisciplinary Aspects of Learning: Physics and Psychology

ERIC Educational Resources Information Center

Oleg, Yavoruk

2015-01-01

The article deals with interdisciplinary aspects of learning in the case of physics and psychology. It describes the lab-based academic course focused on: observation and experimentation; discovery of new scientific facts; measurement; identification of errors; the study of psychological characteristics of people (time perception, the reaction…

77 FR 23660 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-20

..., 120 Baker Lab, Ithaca, NY 14853. Instrument: Pixel Array Detector. Manufacturer: Dectris Ltd... available in conventional charge-coupled device detectors. Justification for Duty- Free Entry: There are no... South Cass Avenue, Lemont, IL 60439. Instrument: Pilatus 100K-S Detector. Manufacturer: Dectris Ltd...

The Great Spray Can Debate.

ERIC Educational Resources Information Center

Bassow, Herb

This booklet, designed to be used in high school classrooms, concerns the technological, economic, and political contexts of the fluorocarbon-ozone depletion controversy. The curriculum is divided into three phases: the scientific dimension, which is a pure science analysis using lab-classroom tools and methodologies; the philosophical dimension,…

The Advanced Lab Course at the University of Houston

NASA Astrophysics Data System (ADS)

Forrest, Rebecca

2009-04-01

The University of Houston Advanced Lab course is designed to help students understand the physics in classic experiments, become familiar with experimental equipment and techniques, gain experience with independent experimentation, and learn to communicate results orally and in writing. It is a two semester course, with a Lab Seminar also required during the first semester. In the Seminar class we discuss keeping a notebook and writing a laboratory report, error analysis, data fitting, and scientific ethics. The students give presentations, in pairs, on the workings and use of basic laboratory equipment. In the Lab courses students do a one week introductory experiment, followed by six two-week experiments each semester. These range from traditional experiments in modern physics to contemporary experiments with superconductivity and chaos. The students are required to keep a laboratory notebook and to write a four-page paper for each experiment in the publication style of the American Institute of Physics. This course introduces students to the experimental tools and techniques used in physics, engineering, and industry laboratories, and allows them to mature as experimentalists.

From trace evidence to bioinformatics: putting bryophytes into molecular biology education.

PubMed

Fuselier, Linda; Bougary, Azhar; Malott, Michelle

2011-01-01

Students benefit most from their science education when they participate fully in the process of science in the context of real-world problems. We describe a student-directed open-inquiry lab experience that has no predetermined outcomes and requires students to engage in all components of scientific inquiry from posing a question through evaluating and reporting results. Over 5 weeks, students learn how bryophytes are used in forensics and become proficient in important molecular biology lab skills including DNA isolation, polymerase chain reaction, gel electrophoresis, capillary electrophoresis, and genotyping. For this portion of the experience, there is no specialized equipment necessary outside of gel electrophoresis supplies and a thermocycler. In an optional extension of the experience, students sequence a plastid intron and use introductory bioinformatics skills to identify species related to their forensics case. Students who participated in the lab experience performed well on content-based assessment, and student attitudes toward the experience were positive and indicative of engaged learning. The lab experience is easily modified for higher or lower level courses and can be used in secondary education. Copyright © 2011 Wiley Periodicals, Inc.

Virus removal retention challenge tests performed at lab scale and pilot scale during operation of membrane units.

PubMed

Humbert, H; Machinal, C; Labaye, Ivan; Schrotter, J C

2011-01-01

The determination of the virus retention capabilities of UF units during operation is essential for the operators of drinking water treatment facilities in order to guarantee an efficient and stable removal of viruses through time. In previous studies, an effective method (MS2-phage challenge tests) was developed by the Water Research Center of Veolia Environnement for the measurement of the virus retention rates (Log Removal Rate, LRV) of commercially available hollow fiber membranes at lab scale. In the present work, the protocol for monitoring membrane performance was transferred from lab scale to pilot scale. Membrane performances were evaluated during pilot trial and compared to the results obtained at lab scale with fibers taken from the pilot plant modules. PFU culture method was compared to RT-PCR method for the calculation of LRV in both cases. Preliminary tests at lab scale showed that both methods can be used interchangeably. For tests conducted on virgin membrane, a good consistency was observed between lab and pilot scale results with the two analytical methods used. This work intends to show that a reliable determination of the membranes performances based on RT-PCR analytical method can be achieved during the operation of the UF units.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- In this closeup, the U.S. Lab Destiny is seen installed in the payload bay of Space Shuttle Atlantis before closure of the doors. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. Destiny will be attached to the Unity node on the ISS using the Shuttle'''s robot arm, seen here on the left side, with the help of an elbow camera attached to the arm (near the upper end of the lab in the photo). This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- The U.S. Lab Destiny rests in the payload bay of Space Shuttle Atlantis before closure of the doors. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. Destiny will be attached to the Unity node on the ISS using the Shuttle'''s robot arm, seen here on the left side, with the help of an elbow camera attached to the arm (near the upper end of the lab in the photo). This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Evaluating Astronomy Laboratories

NASA Astrophysics Data System (ADS)

Zirbel, E. L.

2002-12-01

A set of non-traditional astronomy laboratories for non-science majors will be presented along with evaluations of lab technicians (these labs were originally developed at the College of Staten Island of the City University of New York). The goal of these labs is twofold: (a) to provide the students with hands-on experiences of scientific methodology and (b) to provoke critical thinking. Because non-science majors are often rather resistant to learning the relevant methodology - and especially to thinking critically - this manual is structured differently. It does not only provide traditional cook-book recipes but also contains several leading questions to make the students realize why they are doing what. The students are encouraged to write full sentences and explain how they reach which conclusions. This poster summarizes the experiences of the laboratory assistants that worked with the instructor and presents how they judge the effectiveness of the laboratories.

Geolab Results from Three Years of Analog Mission Tests

NASA Technical Reports Server (NTRS)

Evans, Cindy A.; Bell, M. S.; Calaway, M. J.

2013-01-01

GeoLab is a prototype glovebox for geological sample examination that was, until November 2012, fully integrated into NASA's Deep Space Habitat Analog Testbed [1,2]. GeoLab allowed us to test science operations related to contained sample examination during simulated exploration missions. The facility, shown in Figure 1 and described elsewhere [1-4], was designed for fostering the development of both instrument technology and operational concepts for sample handling and examination during future missions [3-5]. Even though we recently deintegrated the glovebox from the Deep Space Habitat (Fig. 2), it continues to provide a high-fidelity workspace for testing instruments that could be used for sample characterization. As a testbed, GeoLab supports the development of future science operations that will enhance the early scientific returns from exploration missions, and will help ensure selection of the best samples for Earth return.

Immediate Dissemination of Student Discoveries to a Model Organism Database Enhances Classroom-Based Research Experiences

PubMed Central

Wiley, Emily A.; Stover, Nicholas A.

2014-01-01

Use of inquiry-based research modules in the classroom has soared over recent years, largely in response to national calls for teaching that provides experience with scientific processes and methodologies. To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have extended the typical model of inquiry-based labs to include a means for targeted dissemination of student-generated discoveries. This initiative required: 1) creating a set of research-based lab activities with the potential to yield results that a particular scientific community would find useful and 2) developing a means for immediate sharing of student-generated results. Working toward these goals, we designed guides for course-based research aimed to fulfill the need for functional annotation of the Tetrahymena thermophila genome, and developed an interactive Web database that links directly to the official Tetrahymena Genome Database for immediate, targeted dissemination of student discoveries. This combination of research via the course modules and the opportunity for students to immediately “publish” their novel results on a Web database actively used by outside scientists culminated in a motivational tool that enhanced students’ efforts to engage the scientific process and pursue additional research opportunities beyond the course. PMID:24591511

Immediate dissemination of student discoveries to a model organism database enhances classroom-based research experiences.

PubMed

Wiley, Emily A; Stover, Nicholas A

2014-01-01

Use of inquiry-based research modules in the classroom has soared over recent years, largely in response to national calls for teaching that provides experience with scientific processes and methodologies. To increase the visibility of in-class studies among interested researchers and to strengthen their impact on student learning, we have extended the typical model of inquiry-based labs to include a means for targeted dissemination of student-generated discoveries. This initiative required: 1) creating a set of research-based lab activities with the potential to yield results that a particular scientific community would find useful and 2) developing a means for immediate sharing of student-generated results. Working toward these goals, we designed guides for course-based research aimed to fulfill the need for functional annotation of the Tetrahymena thermophila genome, and developed an interactive Web database that links directly to the official Tetrahymena Genome Database for immediate, targeted dissemination of student discoveries. This combination of research via the course modules and the opportunity for students to immediately "publish" their novel results on a Web database actively used by outside scientists culminated in a motivational tool that enhanced students' efforts to engage the scientific process and pursue additional research opportunities beyond the course.

Domain Adaptation Methods for Improving Lab-to-field Generalization of Cocaine Detection using Wearable ECG.

PubMed

Natarajan, Annamalai; Angarita, Gustavo; Gaiser, Edward; Malison, Robert; Ganesan, Deepak; Marlin, Benjamin M

2016-09-01

Mobile health research on illicit drug use detection typically involves a two-stage study design where data to learn detectors is first collected in lab-based trials, followed by a deployment to subjects in a free-living environment to assess detector performance. While recent work has demonstrated the feasibility of wearable sensors for illicit drug use detection in the lab setting, several key problems can limit lab-to-field generalization performance. For example, lab-based data collection often has low ecological validity, the ground-truth event labels collected in the lab may not be available at the same level of temporal granularity in the field, and there can be significant variability between subjects. In this paper, we present domain adaptation methods for assessing and mitigating potential sources of performance loss in lab-to-field generalization and apply them to the problem of cocaine use detection from wearable electrocardiogram sensor data.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

With the lid of the three-story vacuum chamber in place, a worker on top checks release of the cables. Inside the chamber is the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

A worker in the Operations and Checkout Building checks the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

The U.S. Lab is placed in vacuum chamber for leak test

NASA Technical Reports Server (NTRS)

2000-01-01

Workers in the Operations and Checkout Building check the placement of the lid on the vacuum chamber containing the U.S. Lab, a component of the International Space Station. The 32,000-pound scientific research lab, named Destiny, is the first Space Station element to spend seven days in the renovated vacuum chamber for a leak test. Destiny is scheduled to be launched on Shuttle mission STS-98, the 5A assembly mission, targeted for Jan. 18, 2001. During the mission, the crew will install the Lab in the Space Station during a series of three space walks. The STS-98 mission will provide the Station with science research facilities and expand its power, life support and control capabilities. The U.S. Lab module continues a long tradition of microgravity materials research, first conducted by Skylab and later Shuttle and Spacelab missions. Destiny is expected to be a major feature in future research, providing facilities for biotechnology, fluid physics, combustion, and life sciences research.

STS-98 payload U.S. Lab Destiny is moved into Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Workers check out the U.S. Lab Destiny after it has been installed in Atlantis''' payload bay at the pad. Destiny, a key element in the construction of the International Space Station, is 28 feet long and weighs 16 tons. This research and command-and- control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. STS-98 is the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Open Labware: 3-D Printing Your Own Lab Equipment

PubMed Central

Baden, Tom; Chagas, Andre Maia; Gage, Greg; Marzullo, Timothy; Prieto-Godino, Lucia L.; Euler, Thomas

2015-01-01

The introduction of affordable, consumer-oriented 3-D printers is a milestone in the current “maker movement,” which has been heralded as the next industrial revolution. Combined with free and open sharing of detailed design blueprints and accessible development tools, rapid prototypes of complex products can now be assembled in one’s own garage—a game-changer reminiscent of the early days of personal computing. At the same time, 3-D printing has also allowed the scientific and engineering community to build the “little things” that help a lab get up and running much faster and easier than ever before. PMID:25794301

Planetary protection - assaying new methods

NASA Astrophysics Data System (ADS)

Nellen, J.; Rettberg, P.; Horneck, G.

Space age began in 1957 when the USSR launched the first satellite into earth orbit. In response to this new challenge the International Council for Science, formerly know as International Council of Scientific Unions (ICSU), established the Committee on Space Research (COSPAR) in 1958. The role of COSPAR was to channel the international scientific research in space and establish an international forum. Through COSPAR the scientific community agreed on the need for screening interplanetary probes for forward (contamination of foreign planets) and backward (contamination of earth by returned samples/probes) contamination. To prevent both forms of contamination a set of rules, as a guideline was established. Nowadays the standard implementation of the planetary protection rules is based on the experience gained during NASA's Viking project in 1975/76. Since then the evaluation-methods for microbial contamination of spacecrafts have been changed or updated just slowly. In this study the standard method of sample taking will be evaluated. New methods for examination of those samples, based on the identification of life on the molecular level, will be reviewed and checked for their feasibility as microbial detection systems. The methods will be examined for their qualitative (detection and verification of different organisms) and quantitative (detection limit and concentration verification) qualities. Amongst the methods analyzed will be i.e. real-time / PCR (poly-chain-reaction), using specific primer-sets for the amplification of highly conserved rRNA or DNA regions. Measurement of intrinsic fluorescence, i.e ATP using luciferin-luciferase reagents. The use of FAME (fatty acid methyl esters) and microchips for microbial identification purposes. The methods will be chosen to give a good overall coverage of different possible molecular markers and approaches. The most promising methods shall then be lab-tested and evaluated for their use under spacecraft assembly conditions. Since mars became one of the most sought-after planets in our solar system and will be visited by man-made probes quiet often in the near future, planetary protection is as important as never before.

Life's Lessons in the Lab: A Summer of Learning from Undergraduate Research Experiences

ERIC Educational Resources Information Center

Nadelson, Louis S.; Warner, Don; Brown, Eric

2015-01-01

Research experiences for undergraduates (REUs) seek to increase the participating students' knowledge and perceptions of scientific research through engagement in laboratory research and related activities. Various REU outcomes have been investigated including influence on participants' content knowledge, career plans, and general perceptions of…

Integrating Quantitative Skills in Introductory Ecology: Investigations of Wild Bird Feeding Preferences

ERIC Educational Resources Information Center

Small, Christine J.; Newtoff, Kiersten N.

2013-01-01

Undergraduate biology education is undergoing dramatic changes, emphasizing student training in the "tools and practices" of science, particularly quantitative and problem-solving skills. We redesigned a freshman ecology lab to emphasize the importance of scientific inquiry and quantitative reasoning in biology. This multi-week investigation uses…

The Farmer in the Lab

ERIC Educational Resources Information Center

Huss, Jeanine; Baker, Cheryl

2010-01-01

Agriculture can play a key role in fostering scientific literacy because it brings important plant and ecosystem concepts into the classroom. Plus, agriculture, like science, is not static and includes much trial and error, investigation, and innovation. With help from community experts at the U.S. Department of Agriculture-Agricultural Research…

Rare Isotope Beams for the 21st Century

ScienceCinema

James Symons

2017-12-09

In a scientific keynote address on Friday, June 12 at Michigan State University (MSU) in East Lansing, James Symons, Director of Berkeley Labs Nuclear Science Division (NSD), discussed the exciting research prospects of the new Facility for Rare Isotope Beams (FRIB) to be built at MSUs National Superconducting Cyclotron Laboratory.

The Effect of Vocabulary on Introductory Microbiology Instruction

ERIC Educational Resources Information Center

Richter, Emily

2011-01-01

This study examines the effect of the translation of traditional scientific vocabulary into plain English, a process referred to as Anglicization, on student learning in the context of introductory microbiology instruction. Data from Anglicized and Classical-vocabulary lab sections were collected. Data included exam scores as well as pre and…

The Red and White Yeast Lab: An Introduction to Science as a Process.

ERIC Educational Resources Information Center

White, Brian T.

1999-01-01

Describes an experimental system based on an engineered strain of bakers' yeast that is designed to involve students in the process by which scientific knowledge is generated. Students are asked to determine why the yeast grow to form a reproducible pattern of red and white. (WRM)

Innovation Enables New Research on Mutation Linked to Many Cancers | FNLCR Staging

Cancer.gov

A scientific innovation at the Frederick National Lab has opened the way for a new line of experiments in the decades-old quest for a drug to fight cancers triggered by mutant RAS proteins – which underlie one-third of all malignancies, including t

The Energy at ORNL

ScienceCinema

Haberl, Bianca; Shankar, Arjun; Hogle, Susan; Pierce, Eric; Chi, Miaofang; Davidson, Brian; Doughty, Ben; Elliott, Amy; Newby, Jason; Pandya, Tara; Lee, Ho Nyung; Wagner, Robert

2018-06-13

Scientists and engineers at Oak Ridge National Laboratory apply their expertise to the toughest challenges in energy, national security, and scientific discovery. They’re curious, passionate, and motivated, and they explain what drives them in this video from the lab’s annual Awards Night, Nov. 18, 2016.

Laboratory for Oceans

NASA Technical Reports Server (NTRS)

1988-01-01

A review is made of the activities of the Laboratory for Oceans. The staff and the research activities are nearly evenly divided between engineering and scientific endeavors. The Laboratory contributes engineering design skills to aircraft and ground based experiments in terrestrial and atmospheric sciences in cooperation with scientists from labs in Earth sciences.

Injecting Inquiry into Photosynthesis Investigations

ERIC Educational Resources Information Center

Salter, Irene; Smith, Rebecca; Nielsen, Katherine

2008-01-01

This is the story of how a typical middle school lab was transformed into an open-ended inquiry experience through a few small, but very powerful, changes. By allowing students to follow their own questions, the classroom filled with enthusiasm and students learned much more about photosynthesis, respiration, and the scientific processes. The…

Computer Lab Modules as Problem Solving Tools. Final Report.

ERIC Educational Resources Information Center

Ignatz, Mila E.; Ignatz, Milton

There are many problems involved in upgrading scientific literacy in high schools: poorly qualified teachers, the lack of good instructional materials, and economic and academic disadvantages all contribute to the problem. This document describes a project designed to increase the opportunities available to the high school science student to…

The Virtual Research Lab: Research Outcome Expectations, Research Knowledge, and the Graduate Student Experience

ERIC Educational Resources Information Center

Stadtlander, Lee; Giles, Martha; Sickel, Amy

2013-01-01

This paper examines the complexities of working with student researchers in a virtual lab setting, logistics, and methods to resolve issues. To demonstrate the feasibility of a virtual lab, a mixed-methods study consisting of quantitative surveys and qualitative data examined changes in doctoral students' confidence as measured by research outcome…

Lawrence Berkeley National Laboratory 2016 Annual Financial Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Kim, P.; Williams, Kim, P.

FY2016 was a year of significant change and progress at Berkeley Lab. In March, Laboratory Director Michael Witherell assumed his new role when former Lab Director Paul Alivisatos became Vice Chancellor for Research at UC Berkeley. Dr. Witherell has solidified the Lab’s strategy, with a focus on long term science and technology priorities. Large-scale science efforts continued to expand at the Lab, including the Dark Energy Spectroscopic Instrument now heading towards construction, and the LUX-ZEPLIN dark matter detector to be built underground in South Dakota. Another proposed project, the Advanced Light Source-Upgrade, was given preliminary approval and will be themore » Lab’s largest scientific investment in years. Construction of the Integrative Genomics Building began, and will bring together researchers from the Lab’s Joint Genome Institute, now based in Walnut Creek, and the Systems Biology Knowledgebase (K-Base) under one roof. Investment in the Lab’s infrastructure also continues, informed by the Lab’s Infrastructure Strategic Plan. Another important focus is on developing the next generation of scientists with the talent and diversity needed to sustain Berkeley Lab’s scientific leadership and mission contributions to DOE and the Nation. Berkeley Lab received $897.5M in new FY2016 funding, a 12.5% increase over FY2015, for both programmatic and infrastructure activities. While the Laboratory experienced a substantial increase in funding, it was accompanied by only a modest increase in spending, as areas of growth were partially offset by the completion of several major efforts in FY2015. FY2016 costs were $826.9M, an increase of 1.9% over FY2015. Similar to the prior year, the indirect-funded Operations units worked with generally flat budgets to yield more funding for strategic needs. A key challenge for Berkeley Lab continues to be achieving the best balance to fund essential investments, deliver highly effective operational mission support and remain cost-competitive. Through a comprehensive approach to prioritize competing needs, the Lab ended the year in a favorable financial position. The Office of the Chief Financial Officer (OCFO) played a key role in providing analysis and decision support to Executive Leadership, enabling the Lab to enhance its financial management strategies. In FY2016, the OCFO updated its analytic approaches and models to enhance long term financial projections under various funding and investment scenarios, and to assess total cost of ownership for major proposed investments. These improvements provided the new Lab Director and Senior Leadership with more comprehensive information and analytic support for planning and prioritization efforts. Within the OCFO, we focused on core operations and key initiatives defined in our OCFO Strategic Roadmap. The Lab’s Financial System transitioned from stabilization to optimization, with a focus on expanding the financial reporting capabilities considerably. We completed implementation of the eCommerce platform, achieving a notable outcome for the Lab in close partnership with DOE’s Office of Science. In other accomplishments, we launched a financial literacy program to enable Lab managers and staff to understand and execute their financial management and stewardship responsibilities more effectively; made substantial progress in enhancing our Field Finance model that provides financial support to client divisions and areas; developed a business process governance model to define OCFO business processes, clarify roles, and strengthen service delivery; and implemented a Partners in Leadership training program to build leadership capacity among our staff. We completed a ‘refresh’ of our Strategic Roadmap, which now defines our priorities for FY2017-FY2019. As a part of this effort, we made a subtle but important change to the OCFO mission statement to call out the Lab’s research and stewardship mission to sustain the Lab’s science and technology capabilities now and into the future. Berkeley Lab’s FY2016 progress on all fronts - scientific, operations, and financial management – position the Lab to continue bringing science solutions to the world as we charge into the 21st Century.« less

Creating Research-Rich Learning Experiences and Quantitative Skills in a 1st Year Earth Systems Course

NASA Astrophysics Data System (ADS)

King, P. L.; Eggins, S.; Jones, S.

2014-12-01

We are creating a 1st year Earth Systems course at the Australian National University that is built around research-rich learning experiences and quantitative skills. The course has top students including ≤20% indigenous/foreign students; nonetheless, students' backgrounds in math and science vary considerably posing challenges for learning. We are addressing this issue and aiming to improve knowledge retention and deep learning by changing our teaching approach. In 2013-2014, we modified the weekly course structure to a 1hr lecture; a 2hr workshop with hands-on activities; a 2hr lab; an assessment piece covering all face-to-face activities; and a 1hr tutorial. Our new approach was aimed at: 1) building student confidence with data analysis and quantitative skills through increasingly difficult tasks in science, math, physics, chemistry, climate science and biology; 2) creating effective learning groups using name tags and a classroom with 8-person tiered tables; 3) requiring students to apply new knowledge to new situations in group activities, two 1-day field trips and assessment items; 4) using pre-lab and pre-workshop exercises to promote prior engagement with key concepts; 5) adding open-ended experiments to foster structured 'scientific play' or enquiry and creativity; and 6) aligning the assessment with the learning outcomes and ensuring that it contains authentic and challenging southern hemisphere problems. Students were asked to design their own ocean current experiment in the lab and we were astounded by their ingenuity: they simulated the ocean currents off Antarctica; varied water density to verify an equation; and examined the effect of wind and seafloor topography on currents. To evaluate changes in student learning, we conducted surveys in 2013 and 2014. In 2014, we found higher levels of student engagement with the course: >~80% attendance rates and >~70% satisfaction (20% neutral). The 2014 cohort felt that they were more competent in writing and data analysis skills, working quantitatively using spreadsheets; deriving equations to describe nature; using the scientific method; and research processes. Assessment strategies are challenging and we plan to test a grading approach based on the "three Cs": content, correctness and creativity.

EarthLabs Climate Detectives: Using the Science, Data, and Technology of IODP Expedition 341 to Investigate the Earth's Past Climate

NASA Astrophysics Data System (ADS)

Mote, A. S.; Lockwood, J.; Ellins, K. K.; Haddad, N.; Ledley, T. S.; Lynds, S. E.; McNeal, K.; Libarkin, J. C.

2014-12-01

EarthLabs, an exemplary series of lab-based climate science learning modules, is a model for high school Earth Science lab courses. Each module includes a variety of learning activities that allow students to explore the Earth's complex and dynamic climate history. The most recent module, Climate Detectives, uses data from IODP Expedition 341, which traveled to the Gulf of Alaska during the summer of 2013 to study past climate, sedimentation, and tectonics along the continental margin. At the onset of Climate Detectives, students are presented with a challenge engaging them to investigate how the Earth's climate has changed since the Miocene in southern Alaska. To complete this challenge, students join Exp. 341 to collect and examine sediments collected from beneath the seafloor. The two-week module consists of six labs that provide students with the content and skills needed to solve this climate mystery. Students discover how an international team collaborates to examine a scientific problem with the IODP, compete in an engineering design challenge to learn about scientific ocean drilling, and learn about how different types of proxy data are used to detect changes in Earth's climate. The NGSS Science and Engineering Practices are woven into the culminating activity, giving students the opportunity to think and act like scientists as they investigate the following questions: 1) How have environmental conditions in in the Gulf of Alaska changed during the time when the sediments in core U1417 were deposited? (2) What does the occurrence of different types of diatoms and their abundance reveal about the timing of the cycles of glacial advance and retreat? (3) What timeline is represented by the section of core? (4) How do results from the Gulf of Alaska compare with the global record of glaciations during this period based on oxygen isotopes proxies? Developed by educators in collaboration with Expedition 341 scientists, Climate Detectives is a strong example of how learners can engage in authentic research experiences using real data in the secondary science classroom. In this session you will receive a brief overview of the EarthLabs project, learn more about IODP Expedition 341, and see some of the resources that the module makes available to students to help them analyze the data.

Cherry Featured in NCI’s Spotlight on Scientists Video Series | Poster

Cancer.gov

James Cherry, Ph.D., learned at an early age that education is crucial to success. He credits his mentors, some of whom include his grandmother, Shepherd University professor Burton Lidgerding, Ph.D., David Munroe, Ph.D., Frederick National Lab, and Robert J. Hohman, Ph.D., National Institute of Allergy and Infectious Diseases, for guiding him to the career he has today. Cherry, scientific program director, Office of Scientific Operations (OSO), NCI at Frederick, is one of the scientists featured in NCI’s Spotlight on Scientists video series.

European Scientific Notes. Volume 37, Number 5,

DTIC Science & Technology

1983-05-31

along the Maidenhead, UK, 4 - 6 May 1983. route. Total costs are about $6.40 (US) Sixth Workshop on IMS Observations per kilometer to operate and to...Diego, CA Hull HU5 2DW (27-29 June 1983) Aviation Psychology Lab Ohio State Univ. ( 4 - 6 July 1983) Wright-Patterson AFB ( 4 - 6 July 1983) Dr. R.J.A.W...37-5 PD- 3o q/s" 4 . TITLE (end &tbtltio) S. TYPE OF REPORT 0 PEIiOD COVERED Monthly EUROPEAN SCIENTIFIC NOTES May s. PERFORMING ORO. REPORT HUMMER 7

Using a Module-based Laboratory To Incorporate Inquiry into a Large Cell Biology Course

PubMed Central

2005-01-01

Because cell biology has rapidly increased in breadth and depth, instructors are challenged not only to provide undergraduate science students with a strong, up-to-date foundation of knowledge, but also to engage them in the scientific process. To these ends, revision of the Cell Biology Lab course at the University of Wisconsin–La Crosse was undertaken to allow student involvement in experimental design, emphasize data collection and analysis, make connections to the “big picture,” and increase student interest in the field. Multiweek laboratory modules were developed as a method to establish an inquiry-based learning environment. Each module utilizes relevant techniques to investigate one or more questions within the context of a fictional story, and there is a progression during the semester from more instructor-guided to more open-ended student investigation. An assessment tool was developed to evaluate student attitudes regarding their lab experience. Analysis of five semesters of data strongly supports the module format as a successful model for inquiry education by increasing student interest and improving attitude toward learning. In addition, student performance on inquiry-based assignments improved over the course of each semester, suggesting an improvement in inquiry-related skills. PMID:16220145

Genome annotation in a community college cell biology lab.

PubMed

Beagley, C Timothy

2013-01-01

The Biology Department at Salt Lake Community College has used the IMG-ACT toolbox to introduce a genome mapping and annotation exercise into the laboratory portion of its Cell Biology course. This project provides students with an authentic inquiry-based learning experience while introducing them to computational biology and contemporary learning skills. Additionally, the project strengthens student understanding of the scientific method and contributes to student learning gains in curricular objectives centered around basic molecular biology, specifically, the Central Dogma. Importantly, inclusion of this project in the laboratory course provides students with a positive learning environment and allows for the use of cooperative learning strategies to increase overall student success. Copyright © 2012 International Union of Biochemistry and Molecular Biology, Inc.

It Takes a Village: Documenting the Contributions of Non-Scientific Staff to Scientific Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Higgins, Valerie

Documenting the Contributions of Non-Scientific Staff to Scientific Research Science, especially large-scale basic research, is a collaborative endeavor, often drawing on the skills of people from a wide variety of disciplines. These people include not just scientists, but also administrators, engineers, and many others. Fermilab, a Department of Energy National Laboratory and the United States’ premier particle physics laboratory, exemplifies this kind of research; many of its high-energy physics experiments involve hundreds of collaborators from all over the world. The Fermilab Archives seeks to document the history of the lab and the unique scientific research its staff and visitors perform.more » Adequately documenting the lab’s work often requires us to go far beyond things like the writings and correspondence of scientists to also capture the administrative and social histories of the experiments and the context in which they were performed. At Fermilab, we have sought to capture these elements of the lab’s activities through an oral history program that focuses on support staff as well as physicists and collection development choices that recognize the importance of records documenting the cultural life of the lab. These materials are not merely supplementary, but rather essential documentation of the many types of labor that go into the planning and execution of an experiment or the construction of an accelerator and the context in which this work is performed. Any picture of these experiments and accelerators that did not include this type of information would be incomplete. While the importance and richness of this material is especially pronounced at Fermilab due to the massive size of its experiments and accelerator facilities and its vibrant cultural life, the fruitfulness of these collecting efforts at Fermilab suggests that other archives documenting modern STEM research should also make sure the contributions of non-technical and non-scientific staff are preserved and that researchers interested in this subject should not neglect such sources.« less

MLACP: machine-learning-based prediction of anticancer peptides

PubMed Central

Manavalan, Balachandran; Basith, Shaherin; Shin, Tae Hwan; Choi, Sun; Kim, Myeong Ok; Lee, Gwang

2017-01-01

Cancer is the second leading cause of death globally, and use of therapeutic peptides to target and kill cancer cells has received considerable attention in recent years. Identification of anticancer peptides (ACPs) through wet-lab experimentation is expensive and often time consuming; therefore, development of an efficient computational method is essential to identify potential ACP candidates prior to in vitro experimentation. In this study, we developed support vector machine- and random forest-based machine-learning methods for the prediction of ACPs using the features calculated from the amino acid sequence, including amino acid composition, dipeptide composition, atomic composition, and physicochemical properties. We trained our methods using the Tyagi-B dataset and determined the machine parameters by 10-fold cross-validation. Furthermore, we evaluated the performance of our methods on two benchmarking datasets, with our results showing that the random forest-based method outperformed the existing methods with an average accuracy and Matthews correlation coefficient value of 88.7% and 0.78, respectively. To assist the scientific community, we also developed a publicly accessible web server at www.thegleelab.org/MLACP.html. PMID:29100375

A Framework for Information Retrieval and Knowledge Discovery from Online Healthcare Forums

ERIC Educational Resources Information Center

Sampathkumar, Hariprasad

2016-01-01

Information used to assist biomedical and clinical research has largely comprised of data available in published sources like scientific papers and journals, or in clinical sources like patient health records, lab reports and discharge summaries. Information from such sources, though extensive and organized, is often not readily available due to…

Don't Get Buried under a Mountain of Research

ERIC Educational Resources Information Center

Carnahan, Danielle; Fitzpatrick, Michele

2003-01-01

Applying literacy research in the classroom begins with understanding the meaning of scientifically based research and other "lab" terms. From the terminology through key questions to ask yourself when reading research reports, learn how to scrutinize studies to determine their validity--and how applicable they are for your school or district.…

Sustainable Systems SFA 2.0

ScienceCinema

Hubbard, Susan

2018-05-07

Berkeley Lab Earth Sciences Division Director Susan Hubbard, the Project Lead for the Sustainable Systems Scientific Focus Area (SFA) 2.0, gives an overview of the project and its mission to develop a predictive understanding of terrestrial environments, from the genome to the watershed scales, to enable a new class of solutions for environmental and energy solutions.

Sustainable Systems SFA 2.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hubbard, Susan

2015-12-19

Berkeley Lab Earth Sciences Division Director Susan Hubbard, the Project Lead for the Sustainable Systems Scientific Focus Area (SFA) 2.0, gives an overview of the project and its mission to develop a predictive understanding of terrestrial environments, from the genome to the watershed scales, to enable a new class of solutions for environmental and energy solutions.

Case Studies Add Value to a Diverse Teaching Portfolio in Science Courses

ERIC Educational Resources Information Center

Camill, Philip

2006-01-01

Together with lectures and labs, case studies assist students in acquiring content knowledge, process skills, and an understanding of the context and application of science to their daily lives. Cases make the process of scientific learning more genuine and rigorous, bringing alive classroom learning and helping students apply concepts to…

CRISPR/Cas9-mediated genome editing and gene replacement in plants: Transitioning from lab to field

USDA-ARS?s Scientific Manuscript database

The CRISPR/Cas9 genome engineering system has ignited and swept through the scientific community like wildfire. Owing largely to its efficiency, specificity, and flexibility, the CRISPR/Cas9 system has quickly become the preferred genome-editing tool of plant scientists. In plants, much of the earl...

Collaborative Lab Reports with Google Docs

ERIC Educational Resources Information Center

Wood, Michael

2011-01-01

Science is a collaborative endeavor. The solitary genius working on the next great scientific breakthrough is a myth not seen much today. Instead, most physicists have worked in a group at one point in their careers, whether as a graduate student, faculty member, staff scientist, or industrial researcher. As an experimental nuclear physicist with…

Innovation Enables New Research on Mutation Linked to Many Cancers | Frederick National Laboratory for Cancer Research

Cancer.gov

A scientific innovation at the Frederick National Lab has opened the way for a new line of experiments in the decades-old quest for a drug to fight cancers triggered by mutant RAS proteins – which underlie one-third of all malignancies, including t

Creating Metacognitive Awareness in the Lab: Outcomes for Preservice Science Teachers

ERIC Educational Resources Information Center

Saribas, Deniz; Mugaloglu, Ebru Z.; Bayram, Hale

2013-01-01

This study investigated the influence of metacognitive guidance on pre-service science teachers' scientific knowledge, science process skills, and views about the nature of science. The sample included 48 pre-service science teachers taking a first-year chemistry laboratory course in a public university in Turkey. During the 11-week course, the…

Metalloprotease Peptide Inhibitors: A Semester-Long Organic Synthetic Research Project for the Introductory Laboratory Course

ERIC Educational Resources Information Center

Pontrello, Jason K.

2015-01-01

A semester-long research project to synthesize unique compounds designed after published metalloprotease peptide inhibitors is presented. The research project encompasses a set of nine organic chemistry reactions traditionally taught in the second semester lab course, and the procedures are derived from scientific literature. The two principle…

Modeling the Water Balloon Slingshot

ERIC Educational Resources Information Center

Bousquet, Benjamin D.; Figura, Charles C.

2013-01-01

In the introductory physics courses at Wartburg College, we have been working to create a lab experience focused on the scientific process itself rather than verification of physical laws presented in the classroom or textbook. To this end, we have developed a number of open-ended modeling exercises suitable for a variety of learning environments,…

On "Nocilla" and the Urbanization of Consciousness: Multiplicity and Interdisciplinarity in Agustin Fernandez Mallo's Fragmented Trilogy

ERIC Educational Resources Information Center

Fraser, Benjamin

2012-01-01

This essay reappropriates the segmentary form of the three works of Agustin Fernandez Mallo's "Nocilla" project ("Nocilla Dream" [2006]; "Nocilla Experience" [2008]; "Nocilla Lab" [2009]) en route to an urban reading of its fragmentary structure. The project's interdisciplinary push, overwhelming incorporation of both scientific and…

A Very Bright Idea

ERIC Educational Resources Information Center

Cavanagh, Sean

2009-01-01

This article reports that young inventors at a Maryland high school are not only learning scientific principles, but also teamwork and the tenets of patent law. Twice a week, 10 members of the Clarksburg High School's Coyote Inventors Club gather in a second-floor computer lab to peck away at building a deceptively simple device: a cable that…

Applications of UAV imagery for agricultural and environmental research at the USDA Southeast Watershed Research Lab

USDA-ARS?s Scientific Manuscript database

The ARS is the USDA's in-house scientific research agency, whose mission is to conduct research to "develop and transfer solutions to agricultural problems of high national priority..." This includes enhancing the natural resource base and the environment, a dimension of particular relevance to the ...

From Organelle to Protein Gel: A 6-Wk Laboratory Project on Flagellar Proteins

ERIC Educational Resources Information Center

Mitchell, Beth Ferro; Graziano, Mary R.

2006-01-01

Research suggests that undergraduate students learn more from lab experiences that involve longer-term projects. We have developed a one-semester laboratory sequence aimed at sophomore-level undergraduates. In designing this curriculum, we focused on several educational objectives: 1) giving students a feel for the scientific research process, 2)…

76 FR 64966 - Re-Accreditation and Re-Approval of Intertek Caleb Brett as a Commercial Gauger

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-19

....gov/xp/cgov/import/operations_support/labs_scientific_svcs/org_and_operations.xml . DATES: The re... DEPARTMENT OF HOMELAND SECURITY Bureau of Customs and Border Protection Re-Accreditation and Re..., Department of Homeland Security. ACTION: Notice of re-approval of Intertek Caleb Brett, Ponce, Puerto Rico...

KSC-98pc1751

NASA Image and Video Library

1998-12-01

KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility, Program Manager of the International Space Station (ISS) Randy Brinkley addresses the media before unveiling the name of "Destiny" given the U.S. Lab module, the centerpiece of scientific research on the ISS. With Brinkley on the stand are Center Director Roy Bridges (behind him), and (left to right) STS-98 Commander Ken Cockrell, Pilot Mark Polansky, and Mission Specialist Marsha Ivins. The lab, which is behind them on a workstand, is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the International Space Station. Polansky, Cockrell and Ivins are part of the five-member crew expected to be aboard. The Shuttle will spend six days docked to the station while the laboratory is attached and three space walks are conducted to complete its assembly. The laboratory will be launched with five equipment racks aboard, which will provide essential functions for station systems, including high data-rate communications, and maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights

Impact on Scientific Inquiry of a Backwards-Faded Scaffolding Approach to Inquiry-based Space Science for Non-Science Majoring Undergraduates

NASA Astrophysics Data System (ADS)

Lyons, D. J.; Slater, S. J.; Slater, T. F.

2011-12-01

Exploring the impact of a novel inquiry-based earth and space science laboratory curriculum designed using the Backwards Faded Scaffolding inquiry teaching framework on non-science majoring undergraduate students' views of the nature of scientific inquiry (NOSI), this study focused on two aspects of NOSI: The Distinction between Data and Evidence (DvE), and The Multiple Methods of Science (MMS). In the first stage, student participant views of NOSI were measured using the VOSI-4 research instrument before and after the intervention. In the second stage, the quantitative results were used to strategically design a qualitative investigation, in which the four lab instructors were interviewed about their observations of how the student participants interacted with the intervention curriculum as compared to traditional lab activities, as well as their suggestions as to how the curriculum may or may not have contributed to the results of the first stage. These interviews were summarized and analyzed for common themes as to how the intervention curriculum influenced the students' understandings of the two aspect of NOSI. According to the results of a Wilcoxon Signed Rank test, there was a significant shift in the distributions of both samples toward a more informed understanding of DvE after the intervention curriculum was administered, while there was no significant change in either direction for understanding of MMS. The results of the instructor interview analysis suggested that the intervention curriculum provided multiple opportunities for students to evaluate and determine the relevance of data in the context of producing evidence-based conclusions directly related to specific research questions, thereby supporting the development of more informed views of DvE.

Teachers Touch the Sky: A Workshop in Astronomy for Teachers in Grades 3-9

NASA Astrophysics Data System (ADS)

Buratti, B.; Edberg, S.

2011-12-01

Using the natural fascination the public holds towards its work, NASA encourages and funds its scientists to do education and public outreach (E&PO) to both children and adults. Space science is especially interesting to students, less threatening to teachers than some other sciences, and interdisciplinary in nature. These features make it the ideal vehicle for teaching basic scientific concepts to children in a concrete and captivating manner. During the past decade, and again during the summer of 2011, JPL staff and two master teachers conducted a one-week workshop for teachers in grades 3-9. The teachers are walked through hands-on activities that are all based on current projects in astronomy and space science at the Jet Propulsion Lab. The activities are inquiry-based and emphasize the scientific method and fundamental math and science skills. Each year the workshop focuses on a NASA theme: this year it will be the Dawn Mission to the asteroid 4 Vesta, as orbit insertion occurs right before the workshop. At least two activities are based on the Lawrence Livermore Lab's Great Exploration in Math and Science (GEMS) guides. Teachers tour JPL's facilities such as the Space Flight Operations Center, the Spacecraft Assembly Facility, and the Mars Yard. The integration of the lessons into the teachers' own curricula is discussed, and a field trip to JPL's Table Mountain Observatory is included. Teachers learn of the resources NASA makes available to them, and they have the opportunity to talk to "real" scientists about their work. Teachers receive an honorarium for participation plus classroom materials An extensive evaluation is done each year and improvements are made the next year based on the results of the evaluation. Funded by NASA.

The Best and the Brightest in Geosciences: Broadening Representation in the Field

NASA Astrophysics Data System (ADS)

Myles, L.

2017-12-01

Geoscience research in government agencies and universities across the US is anchored by data collection from field and lab experiments. In these settings, the composition and the culture of the environment can be less welcoming for individuals from groups that are traditionally underrepresented in the geosciences. Ongoing efforts to address diversity and inclusion in the field and lab include top-down approaches that provide support and training for established geoscience leaders and bottom-up approaches that offer research internships and fellowships for students. To achieve success, effective strategies for broadening representation in the field must be developed and shared across the geosciences community to advance scientific innovation and create opportunities for success.

Characterizing Mystery Cell Lines: Student-driven Research Projects in an Undergraduate Neuroscience Laboratory Course.

PubMed

Lemons, Michele L

2012-01-01

Inquiry-based projects promote discovery and retention of key concepts, increase student engagement, and stimulate interest in research. Described here are a series of lab exercises within an undergraduate upper level neuroscience course that train students to design, execute and analyze their own hypothesis-driven research project. Prior to developing their own projects, students learn several research techniques including aseptic cell culture, cell line maintenance, immunocytochemistry and fluorescent microscopy. Working in groups, students choose how to use these techniques to characterize and identify a "mystery" cell line. Each lab group is given a unique cell line with either a neural, astrocyte, or Schwann cell origin. Working together, students plan and execute experiments to determine the cellular origin and other unique characteristics of their mystery cell line. Students generate testable hypotheses, design interpretable experiments, generate and analyze data, and report their findings in both oral and written formats. Students receive instructor and peer feedback throughout the entire project. In summary, these labs train students the process of scientific research. This series of lab exercises received very strong positive feedback from the students. Reflections on student feedback and plans for future improvements are discussed.

Characterizing Mystery Cell Lines: Student-driven Research Projects in an Undergraduate Neuroscience Laboratory Course

PubMed Central

Lemons, Michele L.

2012-01-01

Inquiry-based projects promote discovery and retention of key concepts, increase student engagement, and stimulate interest in research. Described here are a series of lab exercises within an undergraduate upper level neuroscience course that train students to design, execute and analyze their own hypothesis-driven research project. Prior to developing their own projects, students learn several research techniques including aseptic cell culture, cell line maintenance, immunocytochemistry and fluorescent microscopy. Working in groups, students choose how to use these techniques to characterize and identify a “mystery” cell line. Each lab group is given a unique cell line with either a neural, astrocyte, or Schwann cell origin. Working together, students plan and execute experiments to determine the cellular origin and other unique characteristics of their mystery cell line. Students generate testable hypotheses, design interpretable experiments, generate and analyze data, and report their findings in both oral and written formats. Students receive instructor and peer feedback throughout the entire project. In summary, these labs train students the process of scientific research. This series of lab exercises received very strong positive feedback from the students. Reflections on student feedback and plans for future improvements are discussed. PMID:23504583

Proteomics research in India: an update.

PubMed

Reddy, Panga Jaipal; Atak, Apurva; Ghantasala, Saicharan; Kumar, Saurabh; Gupta, Shabarni; Prasad, T S Keshava; Zingde, Surekha M; Srivastava, Sanjeeva

2015-09-08

After a successful completion of the Human Genome Project, deciphering the mystery surrounding the human proteome posed a major challenge. Despite not being largely involved in the Human Genome Project, the Indian scientific community contributed towards proteomic research along with the global community. Currently, more than 76 research/academic institutes and nearly 145 research labs are involved in core proteomic research across India. The Indian researchers have been major contributors in drafting the "human proteome map" along with international efforts. In addition to this, virtual proteomics labs, proteomics courses and remote triggered proteomics labs have helped to overcome the limitations of proteomics education posed due to expensive lab infrastructure. The establishment of Proteomics Society, India (PSI) has created a platform for the Indian proteomic researchers to share ideas, research collaborations and conduct annual conferences and workshops. Indian proteomic research is really moving forward with the global proteomics community in a quest to solve the mysteries of proteomics. A draft map of the human proteome enhances the enthusiasm among intellectuals to promote proteomic research in India to the world.This article is part of a Special Issue entitled: Proteomics in India. Copyright © 2015 Elsevier B.V. All rights reserved.

Teaching Science Writing in an Introductory Lab Course

PubMed Central

Holstein, Sarah E.; Mickley Steinmetz, Katherine R.; Miles, John D.

2015-01-01

One challenge that many neuroscience instructors face is how to teach students to communicate within the field. The goal of this project was to improve students’ scientific writing in an introductory psychology laboratory course that serves as a feeder course into the neuroscience curriculum. This course included a scaffolded approach - breaking assignments into different sections that build upon each other to allow for more direction and feedback on each section. Students were also provided with examples of scientific writing, given direction on finding and reading journal articles, and were taught how to effectively peer review a paper. Research papers were assessed before (Year 1) and after (Year 2) this scaffolded approach was instituted. The assessment included measures of “Genre Knowledge” for each section of a research paper (abstract, introduction, method, results, discussion) as well as measures of “Writing Elements” (grammar, formatting, clarity, transitions, building to the hypothesis, using evidence). The results indicated that there was an improvement for Genre Knowledge scores when comparing Year 1 to Year 2. However, there was no systematic improvement in Writing Elements. This suggests that this teaching technique was most effective in improving students’ ability to write within the scientific genre. The logistics of implementing such an approach are discussed. PMID:25838801

Mutation-Based Learning to Improve Student Autonomy and Scientific Inquiry Skills in a Large Genetics Laboratory Course

PubMed Central

Wu, Jinlu

2013-01-01

Laboratory education can play a vital role in developing a learner's autonomy and scientific inquiry skills. In an innovative, mutation-based learning (MBL) approach, students were instructed to redesign a teacher-designed standard experimental protocol by a “mutation” method in a molecular genetics laboratory course. Students could choose to delete, add, reverse, or replace certain steps of the standard protocol to explore questions of interest to them in a given experimental scenario. They wrote experimental proposals to address their rationales and hypotheses for the “mutations”; conducted experiments in parallel, according to both standard and mutated protocols; and then compared and analyzed results to write individual lab reports. Various autonomy-supportive measures were provided in the entire experimental process. Analyses of student work and feedback suggest that students using the MBL approach 1) spend more time discussing experiments, 2) use more scientific inquiry skills, and 3) find the increased autonomy afforded by MBL more enjoyable than do students following regimented instructions in a conventional “cookbook”-style laboratory. Furthermore, the MBL approach does not incur an obvious increase in labor and financial costs, which makes it feasible for easy adaptation and implementation in a large class. PMID:24006394

Big questions, big science: meeting the challenges of global ecology.

PubMed

Schimel, David; Keller, Michael

2015-04-01

Ecologists are increasingly tackling questions that require significant infrastucture, large experiments, networks of observations, and complex data and computation. Key hypotheses in ecology increasingly require more investment, and larger data sets to be tested than can be collected by a single investigator's or s group of investigator's labs, sustained for longer than a typical grant. Large-scale projects are expensive, so their scientific return on the investment has to justify the opportunity cost-the science foregone because resources were expended on a large project rather than supporting a number of individual projects. In addition, their management must be accountable and efficient in the use of significant resources, requiring the use of formal systems engineering and project management to mitigate risk of failure. Mapping the scientific method into formal project management requires both scientists able to work in the context, and a project implementation team sensitive to the unique requirements of ecology. Sponsoring agencies, under pressure from external and internal forces, experience many pressures that push them towards counterproductive project management but a scientific community aware and experienced in large project science can mitigate these tendencies. For big ecology to result in great science, ecologists must become informed, aware and engaged in the advocacy and governance of large ecological projects.

Beyond the lab: observations on the process by which science successfully informs management and policy decisions

NASA Astrophysics Data System (ADS)

Flores, S.

2012-12-01

Scientific findings inform management decisions and policy products through various ways, these include: synthesis reports, white papers, in-person and web-based seminars (webinars), communication from specialized staff, and seminal peer-reviewed journal articles. Scientists are often told that if they want their science to inform management decisions and policy products that they must: clearly and simply articulate discreet pieces of scientific information and avoid attaching advocacy messages to the science; however, solely relying on these tenants does not ensure that scientific products will infuse the realms of management and policy. The process by which science successfully informs management decisions and policy products rarely begins at the time the results come out of the lab, but rather, before the research is carried out. Having an understanding of the political climate, management needs, agency research agendas, and funding limitations, as well as developing a working relationship with the intended managers and policy makers are key elements to developing the kind of science results and products that often make an impact in the management and policy world. In my presentation I will provide case-studies from California (USA) to highlight the type of coastal, ocean and climate science that has been successful in informing management decisions and policy documents, as well as provide a state-level agency perspective on the process by which this occurs.

Scientific Communication and the Nature of Science

NASA Astrophysics Data System (ADS)

Nielsen, Kristian H.

2013-09-01

Communication is an important part of scientific practice and, arguably, may be seen as constitutive to scientific knowledge. Yet, often scientific communication gets cursory treatment in science studies as well as in science education. In Nature of Science (NOS), for example, communication is rarely mentioned explicitly, even though, as will be argued in this paper, scientific communication could be treated as a central component of NOS. Like other forms of communication, scientific communication is socially and symbolically differentiated. Among other things, it encompasses technical language and grammar, lab communications, and peer reviews, all of which will be treated in this paper in an attempt to engage on an empirical and theoretical level with science as communication. Seeing science as a form of communicative action supplements the epistemological view of science that is standard to both NOS and the philosophy of science. Additions to the seven NOS aspects on Lederman's (Handbook of research on science education. Lawrence Erlbaum, Mahwah, pp. 831-879, 2007) list are put forward as well as preliminary thoughts on the inclusion of scientific communication into NOS instruction.

Digital signal processing at Bell Labs-Foundations for speech and acoustics research

NASA Astrophysics Data System (ADS)

Rabiner, Lawrence R.

2004-05-01

Digital signal processing (DSP) is a fundamental tool for much of the research that has been carried out of Bell Labs in the areas of speech and acoustics research. The fundamental bases for DSP include the sampling theorem of Nyquist, the method for digitization of analog signals by Shannon et al., methods of spectral analysis by Tukey, the cepstrum by Bogert et al., and the FFT by Tukey (and Cooley of IBM). Essentially all of these early foundations of DSP came out of the Bell Labs Research Lab in the 1930s, 1940s, 1950s, and 1960s. This fundamental research was motivated by fundamental applications (mainly in the areas of speech, sonar, and acoustics) that led to novel design methods for digital filters (Kaiser, Golden, Rabiner, Schafer), spectrum analysis methods (Rabiner, Schafer, Allen, Crochiere), fast convolution methods based on the FFT (Helms, Bergland), and advanced digital systems used to implement telephony channel banks (Jackson, McDonald, Freeny, Tewksbury). This talk summarizes the key contributions to DSP made at Bell Labs, and illustrates how DSP was utilized in the areas of speech and acoustics research. It also shows the vast, worldwide impact of this DSP research on modern consumer electronics.

Eight year experience in open ended instrumentation laboratory

NASA Astrophysics Data System (ADS)

Marques, Manuel B.; Rosa, Carla C.; Marques, Paulo V. S.

2015-10-01

When designing laboratory courses in a Physics Major we consider a range of objectives: teaching Physics; developing lab competencies; instrument control and data acquisition; learning about measurement errors and error propagation; an introduction to project management; team work skills and scientific writing. But nowadays we face pressure to decrease laboratory hours due to the cost involved. Many universities are replacing lab classes for simulation activities, hiring PhD. and master students to give first year lab classes, and reducing lab hours. This leads to formatted lab scripts and poor autonomy of the students, and failure to enhance creativity and autonomy. In this paper we present our eight year experience with a laboratory course that is mandatory in the third year of Physics and Physical Engineering degrees. Since the students had previously two standard laboratory courses, we focused on teaching instrumentation and giving students autonomy. The course is divided in two parts: one third is dedicated to learn computer controlled instrumentation and data acquisition (based in LabView); the final 2/3 is dedicated to a group project. In this project, the team (2 or 3 students) must develop a project and present it in a typical conference format at the end of the semester. The project assignments are usually not very detailed (about two or three lines long), giving only general guidelines pointing to a successful project (students often recycle objectives putting forward a very personal project); all of them require assembling some hardware. Due to our background, about one third of the projects are related to Optics.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- This closeup reveals the tight clearance between an elbow camera on the robotic arm (left) and the U.S. Lab Destiny when the payload bay doors are closed. Measurements of the elbow camera revealed only a one-inch clearance from the U.S. Lab payload, which is under review. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. Destiny will be attached to the Unity node on the ISS using the Shuttle'''s robot arm, with the help of the camera. This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Methodological possibilities for the solution of new tasks for “Thermophysics of Power Units” Department of SPbPU

NASA Astrophysics Data System (ADS)

Sapozhnikov, S. Z.; Mityakov, V. Yu; Mityakov, A. V.; Gusakov, A. A.

2017-11-01

“Thermophysics of Power Units” Department is based on pre-existed “Thermodynamics and Heat Transfer” and “Reactors and Boilers” Departments. The main goal of the new department (in addition to training students in basic courses of Thermodynamics, Heat and Mass Transfer, Fluid Mechanics, Metrology and Thermal Measurement) has become a new master’s profile “Thermal Engineering, Energy Audit and Energy Service”. It required radical restructuring of the whole educational process, and in the first place - its material resources and equipment. Over the last two years “Heat and Mass Transfer” lab and “Wind tunnel” lab are upgraded, and “Metrology and Thermophysical Measurement” lab is newly created. Tutorials of new generation are changing significantly the structure of our main courses. The members of our scientific group (2 - 6 year students) actively engaged in the work process. Now we hope to see the best of them among our future postgraduates.

Strategic investments in non-communicable diseases (NCD) research in Africa: the GSK Africa NCD Open Lab.

PubMed

Hall, Matthew D; Dufton, Ann M; Katso, Roy M; Gatsi, Sally A; Williams, Pauline M; Strange, Michael E

2015-01-01

In March 2014, GSK announced a number of new strategic investments in Africa. One of these included investment of up to 25 million Pounds Sterling (£25 million) to create the world's first R&D Open Lab to increase understanding of non-communicable diseases (NCDs) in Africa. The vision is to create a new global R&D effort with GSK working in partnership with major funders, academic centres and governments to share expertise and resources to conduct high-quality research. The Africa NCD Open Lab will see GSK scientists collaborate with scientific research centres across Africa. An independent advisory board of leading scientists and clinicians will provide input to develop the strategy and selection of NCD research projects within a dynamic and networked open-innovation environment. It is hoped that these research projects will inform prevention and treatment strategies in the future and will enable researchers across academia and industry to discover and develop new medicines to address the specific needs of African patients.

Biological Course-Based Undergraduate Research Experiences: An Examination of an Introductory Level Implementation

NASA Astrophysics Data System (ADS)

Knoth, Kenneth Charles

Course-based undergraduate research experiences (CUREs) provide authentic research benefits to an entire laboratory course population. CURE experiences are proposed to enhance research skills, critical thinking, productivity, and retention in science. CURE curriculum developers face numerous obstacles, such as the logistics and time commitment involved in bringing a CURE to larger student populations. In addition, an ideal CURE topic requires affordable resources, lab techniques that can be quickly mastered, time for multiple iterations within one semester, and the opportunity to generate new data. This study identifies some of the CURE activities that lead to proposed participant outcomes. Introductory Biology I CURE lab students at Southern Illinois University Edwardsville completed research related to the process of converting storage lipids in microalgae into biodiesel. Data collected from CURE and traditional lab student participants indicate increased CURE student reports of project ownership, scientific self-efficacy, identification as a scientist, and sense of belonging to a science community. Study limitations and unanticipated benefits are discussed.

Research Microcultures as Socialization Contexts for Underrepresented Science Students.

PubMed

Thoman, Dustin B; Muragishi, Gregg A; Smith, Jessi L

2017-06-01

How much does scientific research potentially help people? We tested whether prosocial-affordance beliefs (PABs) about science spread among group members and contribute to individual students' motivation for science. We tested this question within the context of research experience for undergraduates working in faculty-led laboratories, focusing on students who belong to underrepresented minority (URM) groups. Longitudinal survey data were collected from 522 research assistants in 41 labs at six institutions. We used multilevel modeling, and results supported a socialization effect for URM students: The aggregate PABs of their lab mates predicted the students' own initial PABs, as well as their subsequent experiences of interest and their motivation to pursue a career in science, even after controlling for individual-level PABs. Results demonstrate that research labs serve as microcultures of information about the science norms and values that influence motivation. URM students are particularly sensitive to this information. Efforts to broaden participation should be informed by an understanding of the group processes that convey such prosocial values.

Combining Laboratory Experiments with Digital Tools to Do Scientific Inquiry

NASA Astrophysics Data System (ADS)

Kluge, Anders

2014-09-01

This qualitative study investigates the gap between a lab experiment and theory of science. Two groups of 4 students in 2 different classes in 11th grade (15-16 years old) are followed as they process results and experiences from a lab experiment using a digital environment. The experiment is as a part of a larger project about genes and cells, and this study concerns how the digital environment can support students' sensemaking. The study shows how the students only are left with 'how-to' skills before they engage in collaborative processing supported by their own picture from the experiment. The picture becomes a hub for interactive sensemaking and is extensively used for annotation and discussion. Four elements in the digital support are identified as crucial: an extendable point of reference, facilitation to compare and contrast, a pointer to standard science knowledge, and a structure to guide the students to significant issues. The study identifies where the digital support succeeds and fails in this process of sensemaking from a lab experiment.

Bradbury science museum: your window to Los Alamos National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deck, Linda Theresa

The Bradbury Science Museum is the public's window to Los Alamos National Laboratory and supports the Community Program Office's mission to develop community support to accomplish LANL's national security and science mission. It does this by stimulating interest in and increasing basic knowledge of science and technology in northern New Mexico audiences, and increasing public understanding and appreciation of how LANL science and technology solve our global problems. In performing these prime functions, the Museum also preserves the history of scientific accomplishment at the Lab by collecting and preserving artifacts of scientific and historical importance.

Hybrid imaging: a quantum leap in scientific imaging

NASA Astrophysics Data System (ADS)

Atlas, Gene; Wadsworth, Mark V.

2004-01-01

ImagerLabs has advanced its patented next generation imaging technology called the Hybrid Imaging Technology (HIT) that offers scientific quality performance. The key to the HIT is the merging of the CCD and CMOS technologies through hybridization rather than process integration. HIT offers exceptional QE, fill factor, broad spectral response and very low noise properties of the CCD. In addition, it provides the very high-speed readout, low power, high linearity and high integration capability of CMOS sensors. In this work, we present the benefits, and update the latest advances in the performance of this exciting technology.

Telescience testbed pilot program, volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Leiner, Barry M.

1989-01-01

Space Station Freedom and its associated labs, coupled with the availability of new computing and communications technologies, have the potential for significantly enhancing scientific research. A Telescience Testbed Pilot Program (TTPP), aimed at developing the experience base to deal with issues in the design of the future information system of the Space Station era. The testbeds represented four scientific disciplines (astronomy and astrophysics, earth sciences, life sciences, and microgravity sciences) and studied issues in payload design, operation, and data analysis. This volume, of a 3 volume set, which all contain the results of the TTPP, is the executive summary.

Lynda Barry Visits NASA Goddard

NASA Image and Video Library

2017-12-08

Cartoonist and professor of creativity Lynda Barry presented the benefits of creativity in everyday life as part of Goddard's Office of Communications Story Lab seminar series. Read more: www.nasa.gov/feature/goddard/2016/cartoonist-discusses-cr... Credit: NASA/Goddard/Rebecca Roth NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Methods for Specifying Scientific Data Standards and Modeling Relationships with Applications to Neuroscience

PubMed Central

Rübel, Oliver; Dougherty, Max; Prabhat; Denes, Peter; Conant, David; Chang, Edward F.; Bouchard, Kristofer

2016-01-01

Neuroscience continues to experience a tremendous growth in data; in terms of the volume and variety of data, the velocity at which data is acquired, and in turn the veracity of data. These challenges are a serious impediment to sharing of data, analyses, and tools within and across labs. Here, we introduce BRAINformat, a novel data standardization framework for the design and management of scientific data formats. The BRAINformat library defines application-independent design concepts and modules that together create a general framework for standardization of scientific data. We describe the formal specification of scientific data standards, which facilitates sharing and verification of data and formats. We introduce the concept of Managed Objects, enabling semantic components of data formats to be specified as self-contained units, supporting modular and reusable design of data format components and file storage. We also introduce the novel concept of Relationship Attributes for modeling and use of semantic relationships between data objects. Based on these concepts we demonstrate the application of our framework to design and implement a standard format for electrophysiology data and show how data standardization and relationship-modeling facilitate data analysis and sharing. The format uses HDF5, enabling portable, scalable, and self-describing data storage and integration with modern high-performance computing for data-driven discovery. The BRAINformat library is open source, easy-to-use, and provides detailed user and developer documentation and is freely available at: https://bitbucket.org/oruebel/brainformat. PMID:27867355

Living Lab as an Agile Approach in Developing User-Friendly Welfare Technology.

PubMed

Holappa, Niina; Sirkka, Andrew

2017-01-01

This paper discusses living lab as a method of developing user-friendly welfare technology, and presents a qualitative evaluation research of how living lab tested technologies impacted on the life of healthcare customers and professionals over test periods.

Before You Collaborate, You Should Partner with NCI TTC | Poster

Cancer.gov

By Karen Surabian, Thomas Stackhouse, and Jeffrey W. Thomas, Contributing Writers As the fall and winter seasons progress, you may be attending more scientific conferences, where you may find a number of opportunities for research collaborations. To assist your lab in reaching its research goals through collaborations, the staff of the National Cancer Institute Technology

The Influence of Hands On Physics Experiments on Scientific Process Skills According to Prospective Teachers' Experiences

ERIC Educational Resources Information Center

Hirça, Necati

2013-01-01

In this study, relationship between prospective science and technology teachers' experiences in conducting Hands on physics experiments and their physics lab I achievement was investigated. Survey model was utilized and the study was carried out in the 2012 spring semester. Seven Hands on physics experiments were conducted with 28 prospective…

Re-Visioning Science "Love and Passion in the Scientific Imagination": Art and Science

ERIC Educational Resources Information Center

Lunn, M.; Noble, A.

2008-01-01

The often portrayed media image of the scientist is a rather strange one, grim-looking scientists, usually male, poised beside incomprehensible instruments. It is little wonder that we encounter the stereotype of the bespectacled scientist; thick black rims, coke bottle lenses, roman sandals, dressed in lab coats, trousers up to their necks. A…

The Inquiry Flame: Scaffolding for Scientific Inquiry through Experimental Design

ERIC Educational Resources Information Center

Pardo, Richard; Parker, Jennifer

2010-01-01

In the lesson presented in this article, students learn to organize their thinking and design their own inquiry experiments through careful observation of an object, situation, or event. They then conduct these experiments and report their findings in a lab report, poster, trifold board, slide, or video that follows the typical format of the…

Adaptation of Flux-Corrected Transport Algorithms for Modeling Dusty Flows.

DTIC Science & Technology

1983-12-20

Defense Comunications Agency Olcy Attn XLA Washington, DC 20305 01cy Attn nTW-2 (ADR CNW D I: Attn Code 240 for) Olcy Attn NL-STN O Library Olcy Attn...Library Olcy Attn TIC-Library Olcy Attn R Welch Olcy Attn M Johnson Los Alamos National Scientific Lab. Mail Station 5000 Information Science, Inc. P

The Difference That Data Make: Examining Bird Migration Data to Build Scientific Skills

ERIC Educational Resources Information Center

Sturner, Kelly; Lucci, Karen

2015-01-01

This inquiry-based activity for high school students introduces concepts of ecology and the importance of data analysis to science. Using an investigative case, students generate independent questions about birds, access Cornell Lab of Ornithology online resources to collect data, organize and graph data using Excel, and make claims based on…

75 FR 70935 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... below for a complete listing of CBP approved gaugers and accredited laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Intertek USA, Inc., as commercial gauger and laboratory...

75 FR 70935 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... listed below for a complete listing of CBP approved gaugers and accredited laboratories. http:[sol][sol]cbp.gov[sol]xp[sol]cgov[sol]import[sol]operations-- support[sol]labs--scientific--svcs[sol]commercial--gaugers[sol]. DATES: The accreditation and approval of Intertek USA, Inc., as commercial gauger and...

Generating Students' Information Seeking Questions in the Scholar Lab: What Benefits Can We Expect from Inquiry Teaching Approaches?

ERIC Educational Resources Information Center

Torres, Tarcilo; Milicic, Beatriz; Soto, Carlos; Sanjose, Vicente

2013-01-01

Physics teachers use experimental devices to show students how scientific concepts, principles, and laws are applied to understand the real world. This paper studies question generation of secondary and under-graduate university students when they are confronted with experimental devices in different but usual teaching situations: reading about…

From Trace Evidence to Bioinformatics: Putting Bryophytes into Molecular Biology Education

ERIC Educational Resources Information Center

Fuselier, Linda; Bougary, Azhar; Malott, Michelle

2011-01-01

Students benefit most from their science education when they participate fully in the process of science in the context of real-world problems. We describe a student-directed open-inquiry lab experience that has no predetermined outcomes and requires students to engage in all components of scientific inquiry from posing a question through…

Overview of Scientific Freedom and National Security

NASA Astrophysics Data System (ADS)

Lerch, Irving

2000-04-01

The subject of our scrutiny is very much in the news, punctuated with nouns and modifiers both inflammatory and mundane such as espionage, justice, scientific accountability and scientific freedom. And while our discussion will focus on these issues, I want to raise some of the pragmatic questions that bear on the foundation of our support for international science. Beneath questions of guilt and the loss of secrets in the Wen Ho Lee case lay the inherent tension between the tradition of open exchange in the scientific enterprise and the need to protect the nation's security. How this balance is to be achieved in a democratic society has bedeviled us ever since the Manhattan project heralded the emergence of science and technology as instruments of great national power. If we do not find this balance, we run the risk of damaging some of the most important intellectual treasures that the US has produced the Department of Energy's national laboratories and the entire system that we call the international scientific enterprise. For while the superheated charges of lax security and criminal negligence have led some to call for ``firewalls" to isolate and protect the secrets in our weapons labs, such measures may have severe consequences for weapons and non-weapons labs alike and their many associated universities. It's estimated that from 70% to as much as 80% in the expansion of our economy is technology-driven, derived from the most productive system of scientific innovation in the world. This is also true of our national security. Science is indispensable to the development and maintenance of the nation's arsenals. The Department of Energy's Nuclear Stockpile Stewardship Program is central to the safety and reliability of American nuclear weapons and to our hope for a worldwide ban on nuclear tests. But this program will fail without a continuing intense development effort based on cutting-edge science. And a great deal of the science needed is being pursued in fundamental non-weapons-related research around the world. Science expresses the collective intelligence of humankind and it cannot be impounded by any nation. As is true of the world's economy, so is science global. Any impediment to the exchange of ideas serves only to isolate and degrade both international and domestic inquiry. We are faced with two important exigencies: we must safeguard our strategic secrets and maintain our scientific vigor. What we cannot do is permit fear and distrust to drive away our most productive scientists from the national labs and discourage the recruitment of the next generation of young, gifted scientists. We cannot tolerate the abuses of what our national security is designed to protect the Bill of Rights and our Constitutional guarantees. We cannot allow unthinking generalizations that place a cloud of suspicion over Americans and visitors from abroad simply because of their ethnicity. How we achieve this is the question at the core of this symposium.

Awakening interest in the natural sciences - BASF's Kids' Labs.

PubMed

Lang, Cinthia

2012-01-01

At BASF's Ludwigshafen headquarters, kids and young adults in grades 1-13 can learn about chemistry in the Kids' Labs. Different programs exist for different levels of knowledge. In the two 'Hands-on Lab H(2)O & Co.' Kids' Labs, students from grades 1-6 explore the secrets of chemistry. BASF Kids' Labs have now been set up in over 30 countries. In Switzerland alone, almost 2,000 students have taken part in the 'Water Loves Chemistry' Kids' Lab since it was started in 2011. In Alsace, 600 students have participated to date. In the Teens' Lab 'Xplore Middle School', middle school students explore five different programs with the themes 'substance labyrinth', 'nutrition', 'coffee, caffeine & co.', 'cosmetics' and 'energy'. Biotechnological methods are the focus of the Teens' Lab 'Xplore Biotech' for students taking basic and advanced biology courses. In the 'Xplore High School' Teens' Lab, chemistry teachers present their own experimental lab instruction for students in basic and advanced chemistry courses. The Virtual Lab has been expanding the offerings of the BASF Kids' Labs since 2011. The online lab was developed by the company for the International Year Of Chemistry and gives kids and young adults the opportunity to do interactive experiments outside of the lab.

Verification of rapid method for estimation of added food colorant type in boiled sausages based on measurement of cross section color

NASA Astrophysics Data System (ADS)

Jovanović, J.; Petronijević, R. B.; Lukić, M.; Karan, D.; Parunović, N.; Branković-Lazić, I.

2017-09-01

During the previous development of a chemometric method for estimating the amount of added colorant in meat products, it was noticed that the natural colorant most commonly added to boiled sausages, E 120, has different CIE-LAB behavior compared to artificial colors that are used for the same purpose. This has opened the possibility of transforming the developed method into a method for identifying the addition of natural or synthetic colorants in boiled sausages based on the measurement of the color of the cross-section. After recalibration of the CIE-LAB method using linear discriminant analysis, verification was performed on 76 boiled sausages, of either frankfurters or Parisian sausage types. The accuracy and reliability of the classification was confirmed by comparison with the standard HPLC method. Results showed that the LDA + CIE-LAB method can be applied with high accuracy, 93.42 %, to estimate food color type in boiled sausages. Natural orange colors can give false positive results. Pigments from spice mixtures had no significant effect on CIE-LAB results.

Color digital halftoning taking colorimetric color reproduction into account

NASA Astrophysics Data System (ADS)

Haneishi, Hideaki; Suzuki, Toshiaki; Shimoyama, Nobukatsu; Miyake, Yoichi

1996-01-01

Taking colorimetric color reproduction into account, the conventional error diffusion method is modified for color digital half-toning. Assuming that the input to a bilevel color printer is given in CIE-XYZ tristimulus values or CIE-LAB values instead of the more conventional RGB or YMC values, two modified versions based on vector operation in (1) the XYZ color space and (2) the LAB color space were tested. Experimental results show that the modified methods, especially the method using the LAB color space, resulted in better color reproduction performance than the conventional methods. Spatial artifacts that appear in the modified methods are presented and analyzed. It is also shown that the modified method (2) with a thresholding technique achieves a good spatial image quality.

Genelab: Scientific Partnerships and an Open-Access Database to Maximize Usage of Omics Data from Space Biology Experiments

NASA Technical Reports Server (NTRS)

Reinsch, S. S.; Galazka, J..; Berrios, D. C; Chakravarty, K.; Fogle, H.; Lai, S.; Bokyo, V.; Timucin, L. R.; Tran, P.; Skidmore, M.

2016-01-01

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. The GeneLab Data System (GLDS) is NASA's premier open-access omics data platform for biological experiments. GLDS houses standards-compliant, high-throughput sequencing and other omics data from spaceflight-relevant experiments. The GeneLab project at NASA-Ames Research Center is developing the database, and also partnering with spaceflight projects through sharing or augmentation of experiment samples to expand omics analyses on precious spaceflight samples. The partnerships ensure that the maximum amount of data is garnered from spaceflight experiments and made publically available as rapidly as possible via the GLDS. GLDS Version 1.0, went online in April 2015. Software updates and new data releases occur at least quarterly. As of October 2016, the GLDS contains 80 datasets and has search and download capabilities. Version 2.0 is slated for release in September of 2017 and will have expanded, integrated search capabilities leveraging other public omics databases (NCBI GEO, PRIDE, MG-RAST). Future versions in this multi-phase project will provide a collaborative platform for omics data analysis. Data from experiments that explore the biological effects of the spaceflight environment on a wide variety of model organisms are housed in the GLDS including data from rodents, invertebrates, plants and microbes. Human datasets are currently limited to those with anonymized data (e.g., from cultured cell lines). GeneLab ensures prompt release and open access to high-throughput genomics, transcriptomics, proteomics, and metabolomics data from spaceflight and ground-based simulations of microgravity, radiation or other space environment factors. The data are meticulously curated to assure that accurate experimental and sample processing metadata are included with each data set. GLDS download volumes indicate strong interest of the scientific community in these data. To date GeneLab has partnered with multiple experiments including two plant (Arabidopsis thaliana) experiments, two mice experiments, and several microbe experiments. GeneLab optimized protocols in the rodent partnerships for maximum yield of RNA, DNA and protein from tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected on the ground. Analysis of GeneLab data will contribute fundamental knowledge of how the space environment affects biological systems, and as well as yield terrestrial benefits resulting from mitigation strategies to prevent effects observed during exposure to space environments.

"Thinking like a Neuroscientist": Using Scaffolded Grant Proposals to Foster Scientific Thinking in a Freshman Neuroscience Course.

PubMed

Köver, Hania; Wirt, Stacey E; Owens, Melinda T; Dosmann, Andrew J

2014-01-01

Learning and practicing scientific inquiry is an essential component of a STEM education, but it is often difficult to teach to novices or those outside of a laboratory setting. To promote scientific thinking in a freshmen introductory neuroscience course without a lab component, we developed a series of learning activities and assignments designed to foster scientific thinking through the use of scientific grant proposals. Students wrote three short grant proposals on topics ranging from molecular to cognitive neuroscience during a 10-week class (one quarter). We made this challenging and advanced task feasible for novice learners through extensive instructional scaffolding, opportunity for practice, and frequent peer and instructor feedback. Student and instructor reports indicate that the assignments were highly intellectually engaging and that they promoted critical thinking, a deeper understanding of neuroscience material, and effective written communication skills. Here we outline the mechanics of the assignment, student and instructor impressions of learning outcomes, and the advantages and disadvantages of implementing this approach.

“Thinking like a Neuroscientist”: Using Scaffolded Grant Proposals to Foster Scientific Thinking in a Freshman Neuroscience Course

PubMed Central

Köver, Hania; Wirt, Stacey E.; Owens, Melinda T.; Dosmann, Andrew J.

2014-01-01

Learning and practicing scientific inquiry is an essential component of a STEM education, but it is often difficult to teach to novices or those outside of a laboratory setting. To promote scientific thinking in a freshmen introductory neuroscience course without a lab component, we developed a series of learning activities and assignments designed to foster scientific thinking through the use of scientific grant proposals. Students wrote three short grant proposals on topics ranging from molecular to cognitive neuroscience during a 10-week class (one quarter). We made this challenging and advanced task feasible for novice learners through extensive instructional scaffolding, opportunity for practice, and frequent peer and instructor feedback. Student and instructor reports indicate that the assignments were highly intellectually engaging and that they promoted critical thinking, a deeper understanding of neuroscience material, and effective written communication skills. Here we outline the mechanics of the assignment, student and instructor impressions of learning outcomes, and the advantages and disadvantages of implementing this approach. PMID:25565917

Scientific Habits of Mind in Virtual Worlds

NASA Astrophysics Data System (ADS)

Steinkuehler, Constance; Duncan, Sean

2008-12-01

In today's increasingly "flat" world of globalization (Friedman 2005), the need for a scientifically literate citizenry has grown more urgent. Yet, by some measures, we have done a poor job at fostering scientific habits of mind in schools. Recent research on informal games-based learning indicates that such technologies and the communities they evoke may be one viable alternative—not as a substitute for teachers and classrooms, but as an alternative to textbooks and science labs. This paper presents empirical evidence about the potential of games for fostering scientific habits of mind. In particular, we examine the scientific habits of mind and dispositions that characterize online discussion forums of the massively multiplayer online game World of Warcraft. Eighty-six percent of the forum discussions were posts engaged in "social knowledge construction" rather than social banter. Over half of the posts evidenced systems based reasoning, one in ten evidenced model-based reasoning, and 65% displayed an evaluative epistemology in which knowledge is treated as an open-ended process of evaluation and argument.

Development of a structured undergraduate research experience: Framework and implications.

PubMed

Brown, Anne M; Lewis, Stephanie N; Bevan, David R

2016-09-10

Participating in undergraduate research can be a pivotal experience for students in life science disciplines. Development of critical thinking skills, in addition to conveying scientific ideas in oral and written formats, is essential to ensuring that students develop a greater understanding of basic scientific knowledge and the research process. Modernizing the current life sciences research environment to accommodate the growing demand by students for experiential learning is needed. By developing and implementing a structured, theory-based approach to undergraduate research in the life sciences, specifically biochemistry, it has been successfully shown that more students can be provided with a high-quality, high-impact research experience. The structure of this approach allowed students to develop novel, independent projects in a computational molecular modeling lab. Students engaged in an experience in which career goals, problem-solving skills, time management skills, and independence in a research lab were developed. After experiencing this approach to undergraduate research, students reported feeling challenged to think critically and prepared for future career paths. The approach allowed for a progressive learning environment where more undergraduate students could participate in publishable research. Future areas for development include implementation in a bench-top lab and extension to disciplines beyond biochemistry. In this study, it has been shown that utilizing the structured approach to undergraduate research could allow for more students to experience undergraduate research and develop into more confident, independent life scientists well prepared for graduate schools and professional research environments. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(5):463-474, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

Librarians and Scientists Partner to Address Data Management: Taking Collaboration to the Next Level.

PubMed

Medina-Smith, Andrea; Tryka, Kimberly A; Silcox, Barbara P; Hanisch, Robert J

2016-01-01

This study looks at the changing way in which the Information Services Office (ISO) at the National Institute of Standards and Technology (NIST) provides services to NIST scientific and technical staff throughout their research and publishing cycles. These services include the more traditional services of a research library as well as publishing NIST technical reports and The Journal of Research of NIST , and preserving and exhibiting scientific instruments and other artifacts. ISO has always prided itself on having a close relationship with its customers, providing a high level of service, and developing new services to stay in front of NIST researcher needs. Through a concerted, strategic effort since the late 1990s, ISO has developed and promoted relationships with its key customers through its Lab Liaison Program. This paper discusses the relationship ISO has developed with the Office of Data and Informatics (ODI), how this relationship was forged, and how this collaboration will serve as a model for working with the other labs and programs at NIST. It will also discuss the risks and opportunities of this new collaborative service model, how ISO positioned itself to become an equal partner with ODI in the exploration of solutions to data management issues, and the benefits of the relationship from ODI's perspective. A pattern of strategic changes to the services and activities offered by the Lab Liaison program has put ISO in the position to collaborate as peers with researchers at NIST. This study provides an overview of how ISO made strategic decisions to incorporate non-traditional services to support data management at NIST.

Workshop on Incomplete Network Data Held at Sandia National Labs – Livermore

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soundarajan, Sucheta; Wendt, Jeremy D.

2016-06-01

While network analysis is applied in a broad variety of scientific fields (including physics, computer science, biology, and the social sciences), how networks are constructed and the resulting bias and incompleteness have drawn more limited attention. For example, in biology, gene networks are typically developed via experiment -- many actual interactions are likely yet to be discovered. In addition to this incompleteness, the data-collection processes can introduce significant bias into the observed network datasets. For instance, if you observe part of the World Wide Web network through a classic random walk, then high degree nodes are more likely to bemore » found than if you had selected nodes at random. Unfortunately, such incomplete and biasing data collection methods must be often used.« less

Scientific Communication and the Unified Laboratory Sequence1

NASA Astrophysics Data System (ADS)

Silverstein, Todd P.; Hudak, Norman J.; Chapple, Frances H.; Goodney, David E.; Brink, Christina P.; Whitehead, Joyce P.

1997-02-01

The "Temperature Dependent Relaxation Kinetics" lab was first implemented in 1987; it uses stopped-flow pH jump techniques to determine rate constants and activation parameters (H, S, G) for a reaction mechanism. Two new experiments (Monoamine Oxidase, and Molecular Modeling) will be implemented in the fall of 1997. The "Monoamine Oxidase" project uses chromatography and spectrophotometry to purify and characterize the enzyme. Subsequent photometric assays explore the enzyme's substrate specificity, activation energy, and denaturation. Finally, in the "Molecular Modeling"project, students characterize enzyme - substrate and drug - receptor interactions. Energy minimization protocols are used to make predictions about protein structure and ligand binding, and to explore pharmacological and biomedical implications. With these additions, the twelve Unified Laboratory projects introduce our chemistry majors to nearly all of the instrumental methods commonly encountered in modern chemistry.

Learning by Viewing - Nobel Labs 360

NASA Technical Reports Server (NTRS)

Mather, John C.

2013-01-01

First of all, my thanks to the Nobel Lindau Foundation for their inspiration and leadership in sharing the excitement of scientific discovery with the public and with future scientists! I have had the pleasure of participating twice in the Lindau meetings, and recently worked with the Nobel Labs 360 project to show how we are building the world's greatest telescope yet, the James Webb Space Telescope (JWST). For the future, I see the greatest challenges for all the sciences in continued public outreach and inspiration. Outreach, so the public knows why we are doing what we are doing, and what difference it makes for them today and in the long-term future. Who knows what our destiny may be? It could be glorious, or not, depending on how we all behave. Inspiration, so that the most creative and inquisitive minds can pursue the scientific and engineering discoveries that are at the heart of so much of human prosperity, health, and progress. And, of course, national and local security depend on those discoveries too; scientists have been working with "the government" throughout recorded history. For the Lindau Nobel experiment, we have a truly abundant supply of knowledge and excitement, through the interactions of young scientists with the Nobelists, and through the lectures and the video recordings we can now share with the whole world across the Internet. But the challenge is always to draw attention! With 7 billion inhabitants on Earth, trying to earn a living and have some fun, there are plenty of competing opportunities and demands on us all. So what will draw attention to our efforts at Lindau? These days, word of mouth has become word of (computer) mouse, and ideas propagate as viruses ( or memes) across the Internet according to the interests of the participants. So our challenge is to find and match those interests, so that the efforts of our scientists, photographers, moviemakers, and writers are rewarded by our public. The world changes every day, so there is no one way to go, and everything is an experiment - sounds scientific, yes? I think our partnership with Volker Steger in the Nobel Labs 360 is one of the most interesting I have seen. Computer viewers can see our scientific habitats and begin to experience being there in person, panning a viewpoint up, down, and all around us, and seeing or hearing explanations of what we are doing.

Qualitative investigation of students' views about experimental physics

NASA Astrophysics Data System (ADS)

Hu, Dehui; Zwickl, Benjamin M.; Wilcox, Bethany R.; Lewandowski, H. J.

2017-12-01

This study examines students' reasoning surrounding seemingly contradictory Likert-scale responses within five items in the Colorado Learning Attitudes About Science Survey for Experimental Physics (E-CLASS). We administered the E-CLASS with embedded open-ended prompts, which asked students to provide explanations after making a Likert-scale selection. The quantitative scores on those items showed that our sample of the 216 students enrolled in first year and beyond first year physics courses demonstrated the same trends as previous national data. A qualitative analysis of students' open-ended responses was used to examine common reasoning patterns related to particular Likert-scale responses. When explaining responses to items regarding the role of experiments in confirming known results and also contributing to the growth of scientific knowledge, a common reasoning pattern suggested that confirming known results in a classroom experiment can help with understanding concepts. Thus, physics experiments contribute to students' personal scientific knowledge growth, while also confirming widely known results. Many students agreed that having correct formatting and making well-reasoned conclusions are the main goal for communicating experimental results. Students who focused on sections and formatting emphasized how it enables clear and efficient communication. However, very few students discussed the link between well-reasoned conclusions and effective scientific communication. Lastly, many students argued it was possible to complete experiments without understanding equations and physics concepts. The most common justification was that they could simply follow instructions to finish the lab without understanding. The findings suggest several implications for teaching physics laboratory courses, for example, incorporating some lab activities with outcomes that are unknown to the students might have a significant impact on students' understanding of experiments as an important approach for developing scientific knowledge.

DNA Everywhere. A Guide for Simplified Environmental Genomic DNA Extraction Suitable for Use in Remote Areas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gabrielle N. Pecora; Francine C. Reid; Lauren M. Tom

2016-05-01

Collecting field samples from remote or geographically distant areas can be a financially and logistically challenging. With participation of a local organization where the samples are originated from, gDNA samples can be extracted from the field and shipped to a research institution for further processing and analysis. The ability to set up gDNA extraction capabilities in the field can drastically reduce cost and time when running long-term microbial studies with a large sample set. The method outlined here has developed a compact and affordable method for setting up a “laboratory” and extracting and shipping gDNA samples from anywhere in themore » world. This white paper explains the process of setting up the “laboratory”, choosing and training individuals with no prior scientific experience how to perform gDNA extractions and safe methods for shipping extracts to any research institution. All methods have been validated by the Andersen group at Lawrence Berkeley National Laboratory using the Berkeley Lab PhyloChip.« less

Single Investigator or Group Projects? Which is the More Successful Model for a REU Site?

NASA Astrophysics Data System (ADS)

Boush, L. P.; Myrbo, A.; Berman, M. J.; Gnivecki, P.; Michelson, A.; Brady, K. L.

2012-12-01

Undergraduate research programs have become popular and effective mechanisms for developing future geoscientists and increasing participation of under-represented groups in the sciences. There are many models for implementing such programs that span different philosophies and goals. Our Research Experience for Undergraduates (REU) program in the Bahamas is in the second of its three year award and has used two different models each year of its operation. In the first year, we used the individual student project model, where students pursued their own research much like an honors or masters thesis approach. Specifically, students did individual projects in four areas: paleobiology, geoarcheology, geobiology and limnogeology. In the second year, we used the team concept model, where students were divided into two teams, coring different lakes. The students combined efforts in both the field and lab, doing basic limnology of the basins, and then collecting and analyzing the cores that they took. While both pedagogy models were successful in teaching basic science skills in the field and lab, each one had different strengths and weaknesses. The single investigator model allowed students to have complete intellectual ownership of their projects, while the group model allowed students to work together in teams and produce a more comprehensive dataset that was higher quality and more likely to be published. In addition, while student knowledge gains were statistically the same for both years, the attitudes towards science scores were higher for the 'team model' year than for the single investigator. Since one of the goals of the REU program is to engage students and foster a desire to continue scientific inquiry or careers in science, the 'team model' could be regarded as more successful. It also allowed higher quality datasets to be produced and a more realistic view of how most science is done—in a collaborative, multidisciplinary way. Each student learned all of the field and lab techniques and helped one another as a cooperative group but was held individually responsible for various aspects of the data collection and analysis. Further, it can be argued that in the short amount of time allotted for REU projects (8-10 weeks), it is difficult for inexperienced students to design a publishable project; and one could question if this is the appropriate venue for having students initiate either projects that are too large to do in the timeframe of the REU or too specific or limited in data and methods to be significant scientific contributions. Thus, we will pursue the 'team model' in our third year of our REU project because it has yielded better scientific outcomes and more satisfying experiences for our students.

Challenges in Characterizing Low-Temperature Regolith Properties

NASA Technical Reports Server (NTRS)

Swanger, Adam Michael; Mantovani, James G.

2014-01-01

The success or failure of in-situ resource utilization for planetary surface exploration--be it for scientific, colonization or commercialization purposes--relies heavily on the ability to design and implement systems which effectively process the associated regolith and exploit its benefits. In most cases this challenge necessarily includes the characterization of low-temperature (cryogenic) properties; as many celestial destinations of interest, such as the moon, Mars and asteroids, have little or no atmosphere to help sustain the consistently "high" surface temperatures seen on planets such as Earth, and therefore can experience permanent cryogenic temperatures or dramatic cyclical changes. Characterization of physical properties (such as specific heat, thermal and electrical conductivity, etc.) over the entire temperature profile is undoubtedly an important piece of the puzzle; however, the impact on mechanical properties due to the introduction of icy deposit must also be explored in order to devise effective and robust excavation technologies. Currently the Granular Mechanics and Regolith Operations Lab and the Cryogenics Test Lab at NASA Kennedy Space Center are developing technologies and experimental methods to address these challenges and aid in the characterization of physical and mechanical properties of regolith at cryogenic temperatures. This presentation will review the current state of knowledge concerning lunar regolith at low temperature including that of icy regolith.

EarthTutor: An Interactive Intelligent Tutoring System for Remote Sensing

NASA Astrophysics Data System (ADS)

Bell, A. M.; Parton, K.; Smith, E.

2005-12-01

Earth science classes in colleges and high schools use a variety of satellite image processing software to teach earth science and remote sensing principles. However, current tutorials for image processing software are often paper-based or lecture-based and do not take advantage of the full potential of the computer context to teach, immerse, and stimulate students. We present EarthTutor, an adaptive, interactive Intelligent Tutoring System (ITS) being built for NASA (National Aeronautics and Space Administration) that is integrated directly with an image processing application. The system aims to foster the use of satellite imagery in classrooms and encourage inquiry-based, hands-on earth science scientific study by providing students with an engaging imagery analysis learning environment. EarthTutor's software is available as a plug-in to ImageJ, a free image processing system developed by the NIH (National Institute of Health). Since it is written in Java, it can be run on almost any platform and also as an applet from the Web. Labs developed for EarthTutor combine lesson content (such as HTML web pages) with interactive activities and questions. In each lab the student learns to measure, calibrate, color, slice, plot and otherwise process and analyze earth science imagery. During the activities, EarthTutor monitors students closely as they work, which allows it to provide immediate feedback that is customized to a particular student's needs. As the student moves through the labs, EarthTutor assesses the student, and tailors the presentation of the content to a student's demonstrated skill level. EarthTutor's adaptive approach is based on emerging Artificial Intelligence (AI) research. Bayesian networks are employed to model a student's proficiency with different earth science and image processing concepts. Agent behaviors are used to track the student's progress through activities and provide guidance when a student encounters difficulty. Through individual feedback and adaptive instruction, EarthTutor aims to offer the benefits of a one-on-one human instructor in a cost-effective, easy-to-use application. We are currently working with remote sensing experts to develop EarthTutor labs for diverse earth science subjects such as global vegetation, stratospheric ozone, oceanography, polar sea ice and natural hazards. These labs will be packaged with the first public release of EarthTutor in December 2005. Custom labs can be designed with the EarthTutor authoring tool. The tool is basic enough to allow teachers to construct tutorials to fit their classroom's curriculum and locale, but also powerful enough to allow advanced users to create highly-interactive labs. Preliminary results from an ongoing pilot study demonstrate that the EarthTutor system is effective and enjoyable teaching tool, relative to traditional satellite imagery teaching methods.

Networking Labs in the Online Environment: Indicators for Success

ERIC Educational Resources Information Center

Lahoud, Hilmi A.; Krichen, Jack P.

2010-01-01

Several techniques have been used to provide hands-on educational experiences to online learners, including remote labs, simulation software, and virtual labs, which offer a more structured environment, including simulations and scheduled asynchronous access to physical resources. This exploratory study investigated how these methods can be used…

Climate and the Carbon Cycle

NASA Astrophysics Data System (ADS)

Manley, Jim

2017-04-01

Climate and the Carbon Cycle EOS3a Science in tomorrow's classroom Students, like too much of the American public, are largely unaware or apathetic to the changes in world climate and the impact that these changes have for life on Earth. A study conducted by Michigan State University and published in 2011 by Science Daily titled 'What carbon cycle? College students lack scientific literacy, study finds'. This study relates how 'most college students in the United States do not grasp the scientific basis of the carbon cycle - an essential skill in understanding the causes and consequences of climate change.' The study authors call for a new approach to teaching about climate. What if teachers better understood vital components of Earth's climate system and were able to impart his understanding to their students? What if students based their responses to the information taught not on emotion, but on a deeper understanding of the forces driving climate change, their analysis of the scientific evidence and in the context of earth system science? As a Middle School science teacher, I have been given the opportunity to use a new curriculum within TERC's EarthLabs collection, Climate and the Carbon Cycle, to awaken those brains and assist my students in making personal lifestyle choices based on what they had learned. In addition, with support from TERC and The University of Texas Institute for Geophysics I joined others to begin training other teachers on how to implement this curriculum in their classrooms to expose their students to our changing climate. Through my poster, I will give you (1) a glimpse into the challenges faced by today's science teachers in communicating the complicated, but ever-deepening understanding of the linkages between natural and human-driven factors on climate; (2) introduce you to a new module in the EarthLabs curriculum designed to expose teachers and students to global scientific climate data and instrumentation; and (3) illustrate how student worldviews are changed though exposure to the latest in scientific discovery and understanding.

Are Africans, Europeans, and Asians different "races"? A guided-inquiry lab for introducing undergraduate students to genetic diversity and preparing them to study natural selection.

PubMed

Kalinowski, Steven T; Andrews, Tessa M; Leonard, Mary J; Snodgrass, Meagan

2012-01-01

Many students do not recognize that individual organisms within populations vary, and this may make it difficult for them to recognize the essential role variation plays in natural selection. Also, many students have weak scientific reasoning skills, and this makes it difficult for them to recognize misconceptions they might have. This paper describes a 2-h laboratory for college students that introduces them to genetic diversity and gives them practice using hypothetico-deductive reasoning. In brief, the lab presents students with DNA sequences from Africans, Europeans, and Asians, and asks students to determine whether people from each continent qualify as distinct "races." Comparison of the DNA sequences shows that people on each continent are not more similar to one another than to people on other continents, and therefore do not qualify as distinct races. Ninety-four percent of our students reported that the laboratory was interesting, and 79% reported that it was a valuable learning experience. We developed and used a survey to measure the extent to which students recognized variation and its significance within populations and showed that the lab increased student awareness of variation. We also showed that the lab improved the ability of students to construct hypothetico-deductive arguments.

Explore Galaxies Far, Far Away at Internet Speeds | Berkeley Lab

Science.gov Websites

Survey) were taken by the 520-megapixel Dark Energy Survey Camera (DECam). The scientific aim of DECaLS the Dark Energy Camera Legacy Survey (DECaLS). Credit: Dustin Lang/University of Toronto This galaxy UGC 10041 imaged by the Dark Energy Camera Legacy Survey (DECaLS). Credit: Dustin Lang/University

Learning by Doing: The Objectification of Knowledge across Semiotic Modalities in Middle School Chemistry Lab Activities

ERIC Educational Resources Information Center

Wright, Laura J.

2008-01-01

This analysis follows students' action and interaction with a single scientific phenomenon (bubbling/gas) over the course of a curriculum unit in a middle school science classroom to examine how and what they learn when doing laboratory activities. Taking a situated approach to interaction, I place the process of objectification in its multimodal…

Using a Module-Based Laboratory to Incorporate Inquiry into a Large Cell Biology Course

ERIC Educational Resources Information Center

Howard, David R.; Miskowski, Jennifer A.

2005-01-01

Because cell biology has rapidly increased in breadth and depth, instructors are challenged not only to provide undergraduate science students with a strong, up-to-date foundation of knowledge, but also to engage them in the scientific process. To these ends, revision of the Cell Biology Lab course at the University of Wisconsin-La Crosse was…

Growing a Thicker Skin: An Exercise for Measuring Organismal Adaptations to Terrestrial Habitats

ERIC Educational Resources Information Center

Nash, Troy R.; Yang, Suann; Inman, John C.

2015-01-01

We describe an alternative to the kinds of observation-based lab exercises that are often used to cover animal and plant evolution with respect to transitioning from aquatic to terrestrial habitats. We wrote this activity to address these objectives, but also to model the process of scientific inquiry and to require students to collect and analyze…

The Writing of the Scientific Paper To Help Students Process Water Quality Data.

ERIC Educational Resources Information Center

Friday, Gerald

This paper describes how a water monitoring program uses a science research paper to help students apply knowledge learned from the field, the lab, and class discussion. The application consists of examining water quality data of a river and determining what factors had an impact on the river, either biotic or abiotic. Students are asked to…

KSC-98pc1753

NASA Image and Video Library

1998-12-01

KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility, Program Manager of the International Space Station (ISS) Randy Brinkley addresses the media before lowering the banner to unveil the name of "Destiny" given the U.S. Lab module, the centerpiece of scientific research on the ISS. With Brinkley on the stand are Center Director Roy Bridges (behind him on the left), and (the other side, left to right) STS-98 Commander Ken Cockrell, Pilot Mark Polansky, and Mission Specialist Marsha Ivins. The lab, which is behind them on a workstand, is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the International Space Station. Polansky, Cockrel and Ivins are part of the five-member crew expected to be aboard. The Shuttle will spend six days docked to the station while the laboratory is attached and three space walks are conducted to complete its assembly. The laboratory will be launched with five equipment racks aboard, which will provide essential functions for station systems, including high data-rate communications, and maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springston, Stephen R.

The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO 2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO 2 + hυ1 →SO 2 *→SO 2 + hυ2 The emitted light is proportional to the concentration of SO 2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed tomore » interface with external computers through the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. Brookhaven National Laboratory (BNL) has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.« less

Analysis of current laboratory animal science policies and administration in China.

PubMed

Kong, Qi; Qin, Chuan

2009-01-01

Laboratory animal science (LAS) advances scientific understanding of the care and use of animals that play a key role in research supporting the development of biomedicine. LAS has developed quickly in China in recent decades, and this report provides an analysis of the current status of the countrys LAS policies and administration. National and provincial laws, regulations, guidelines, and standards apply to quality control and licensing, quarantine and infectious disease control, breeding and husbandry, transgenic animals, staff qualifications, animal welfare, and imports, exports, and transportation. Regulation and oversight of lab animal use are the responsibility of the national Ministry of Science and Technology, provincial departments of science and technology, and institutional animal care and use committees. We begin with an explanation of the rationale behind this paper and then offer a brief history of policy-related activities and achievements. We then present various policies, discuss their implementation, and hypothesize about future policy developments. With the improvement of policies under an integrated, multitiered administration, the use of high-quality lab animals in Chinese scientific research is increasing and many more papers describing animal experiments performed in China are being published in international journals.

Secondary students in professional laboratories: Discoveries about science learning in a community of practitioners

NASA Astrophysics Data System (ADS)

Song, Mary Elizabeth

This study explores what educators may learn from the experiences of secondary students working in professional scientific laboratories. My investigation is guided by the methodology of phenomenological; I depend primarily on interviews conducted with students and professional researchers. This material is supported primarily by on-site observations, and by informal conversations between me and the study participants. My dissertation has three goals: (one) to use the work of secondary students in scientific research laboratories to consider how they know the discipline; (two) to distinguish the students' professional accomplishments from science learning at school; and, (three) to engage readers in a reflection about authority within the scientific community, and the possibility that by accomplishing research, students take their legitimate place among those who construct scientific knowledge. My methods and focus have allowed me to capture qualities of the student narratives that support the emergence of three major themes: the importance of doing "real work" in learning situations; the inapplicability of "school learning" to professional research arenas; and the inclusive nature of the scientific community. At the same time, the study is confined by the narrow pool of participants I interviewed over a short period of time. These talented students were all academically successful, articulate, "well-rounded" and in this sense, mature. They typically had strong family support, and they talked about ideas with their parents. Indeed, the students were all capable story-tellers who were anxious to share their experiences publicly. Yet they themselves remind the reader of their struggles to overcome naivete in the lab. By doing so they suggested to me that their experiences might be accessible to a broad range of young men and women; thus this study is a good beginning for further research.

Doing, talking and writing science: A discourse analysis of the process of resemiotization in a middle school lab-based science class

NASA Astrophysics Data System (ADS)

Wright, Laura J.

This study examines students' sense making practices in a middle school science class from a discourse analytic perspective. Using Mediated Discourse Analysis (MDA) (Scollon 1998, 2001) and interactional sociolinguistics (Gumperz 1999, 2001, Schiffrin 1994), my research seeks to enrich findings from recent sociocultural studies of science classrooms that focus on doing, talking and writing science (Roth 2005, Kress, et al. 2002, Halliday & Martin 1993, Lemke 1990). Within a middle school science classroom, these fundamental activities form a nexus of practice (Scollon 1998, 2001) basic to science literacy (AAAS 1989) and reflective of the work of practicing scientists. Moreover, students' engagement in these practices provides insight into the cultural production and reproduction of science and scientist. I first examine how the students' curriculum text encourages these three scientific practices and then trace students' uptake; that is, how they subsequently do, talk, and write science throughout the course of the unit. I argue that learning science with this curriculum unit requires students to resemiotize (Iedema 2001, 2003) first hand experience so they can represent their knowledge cohesively and coherently in evaluable forms. Ultimately, students must transform language from the curriculum text and their teacher into action in their laboratory activities and action in their laboratory activities into language. In addition, I show how students are apprenticed to the conventionalized practices and voices (Bakhtin 1986) of science (i.e. the scientific register), and how their figures of personhood (Agha 2005) reflect the development of their scientific identities. Overall, I argue that the microanalytic methods I use illuminate how students draw upon curricular resources to become scientifically literate and develop scientific identities.

Impact of backwards faded scaffolding approach to inquiry-based astronomy laboratory experiences on undergraduate non-science majors' views of scientific inquiry

NASA Astrophysics Data System (ADS)

Lyons, Daniel J.

This study explored the impact of a novel inquiry-based astronomy laboratory curriculum designed using the Backwards Faded Scaffolding inquiry teaching framework on non-science majoring undergraduate students' views of the nature of scientific inquiry (NOSI). The study focused on two aspects of NOSI: The Distinction between Data and Evidence (DvE), and The Multiple Methods of Science (MMS). Participants were 220 predominately non-science majoring undergraduate students at a small, doctoral granting, research-extensive university in the Rocky Mountain region of the United States. The student participants were enrolled in an introductory astronomy survey course with an associated laboratory section and were selected in two samples over consecutive fall and spring semesters. The participants also included four of the graduate student instructors who taught the laboratory courses using the intervention curriculum. In the first stage, student participant views of NOSI were measured using the VOSI-4 research instrument before and after the intervention curriculum was administered. The responses were quantified, and the distributions of pre and posttest scores of both samples were separately analyzed to determine if there was a significant improvement in understanding of either of the two aspects of NOSI. The results from both samples were compared to evaluate the consistency of the results. In the second stage, the quantitative results were used to strategically design a qualitative investigation, in which the four lab instructors were interviewed about their observations of how the student participants interacted with the intervention curriculum as compared to traditional lab activities, as well as their suggestions as to how the curriculum may or may not have contributed to the results of the first stage. These interviews were summarized and analyzed for common themes as to how the intervention curriculum influenced the students' understandings of the two aspect of NOSI. According to the results of a Wilcoxon Signed Rank test, there was a significant shift in the distributions of both samples toward a more informed understanding of DvE after the intervention curriculum was administered, while there was no significant change in either direction for understanding of MMS. The results of the instructor interview analysis suggested that the intervention curriculum provided multiple opportunities for students to evaluate and determine the relevance of data in the context of producing evidence-based conclusions directly related to specific research questions, thereby supporting the development of more informed views of DvE. These results also suggested that students might not have realized that they were exclusively engaged in non-experimental type inquiries, as various research methods were not explicitly addressed. The intervention curriculum used a consistently phased stepwise format, which may also have led the students to accommodate their astronomy inquiry experiences within persistent misconceptions of "The Scientific Method" as the only valid means of constructing scientific knowledge, thereby leading to no change in understanding of MMS. The results of the study suggest that a scaffolded, inquiry-based, introductory astronomy laboratory curriculum purposefully designed and scaffolded to enhance students' understandings could be effective in enhancing undergraduate non-science majoring students' views of certain aspects of NOSI. Through scaffolding inquiry experiences that deliver multiple opportunities to engage in authentic scientific inquiries, the novel curriculum provides a valuable resource for the astronomy education community to engage students in learning experiences that reflect the contemporary views of constructivist inquiry-based learning, which focuses on the interpretation of data to create evidence in light of specific questions, as well as opportunities to engage in authentic scientific discourse. As such it can enable astronomy educators in the undergraduate teaching community to support student learning beyond astronomy content knowledge toward a more informed understanding of the process of scientific knowledge construction to the end of supporting proficiency in science and science literacy.

Determination of the δ15N of nitrate in solids; RSIL lab code 2894

USGS Publications Warehouse

Coplen, Tyler B.; Qi, Haiping; Revesz, Kinga; Casciotti, Karen; Hannon, Janet E.

2007-01-01

The purpose of the Reston Stable Isotope Laboratory (RSIL) lab code 2894 is to determine the δ15N of nitrate (NO3-) in solids. The nitrate fraction of the nitrogen species is dissolved by water (called leaching) and can be analyzed by the bacterial method covered in RSIL lab code 2899. After leaching, the δ15N of the dissolved NO3- is analyzed by conversion of the NO3- to nitrous oxide (N2O), which serves as the analyte for mass spectrometry. A culture of denitrifying bacteria is used in the enzymatic conversion of NO3- to N2O, which follows the pathway shown in equation 1: NO3- → NO2- → NO → 1/2 N2O (1) Because the bacteria Pseudomonas aureofaciens lack N2O reductive activity, the reaction stops at N2O, unlike the typical denitrification reaction that goes to N2. After several hours, the conversion is complete, and the N2O is extracted from the vial, separated from volatile organic vapor and water vapor by an automated -65 °C isopropanol-slush trap, a Nafion drier, a CO2 and water removal unit (Costech #021020 carbon dioxide absorbent with Mg(ClO4)2), and trapped in a small-volume trap immersed in liquid nitrogen with a modified Finnigan MAT (now Thermo Scientific) GasBench 2 introduction system. After the N2O is released, it is further purified by gas chromatography before introduction to the isotope-ratio mass spectrometer (IRMS). The IRMS is a Thermo Scientific Delta V Plus continuous flow IRMS (CF-IRMS). It has a universal triple collector, consisting of two wide cups with a narrow cup in the middle; it is capable of simultaneously measuring mass/charge (m/z) of the N2O molecule 44, 45, and 46. The ion beams from these m/z values are as follows: m/z = 44 = N2O = 14N14N16O; m/z = 45 = N2O = 14N15N16O or 14N14N17O; m/z = 46 = N2O = 14N14N18O. The 17O contributions to the m/z 44 and m/z 45 ion beams are accounted for before δ15N values are reported.

A research education program model to prepare a highly qualified workforce in biomedical and health-related research and increase diversity.

PubMed

Crockett, Elahé T

2014-09-24

The National Institutes of Health has recognized a compelling need to train highly qualified individuals and promote diversity in the biomedical/clinical sciences research workforce. In response, we have developed a research-training program known as REPID (Research Education Program to Increase Diversity among Health Researchers) to prepare students/learners to pursue research careers in these fields and address the lack of diversity and health disparities. By inclusion of students/learners from minority and diverse backgrounds, the REPID program aims to provide a research training and enrichment experience through team mentoring to inspire students/learners to pursue research careers in biomedical and health-related fields. Students/learners are recruited from the University campus from a diverse population of undergraduates, graduates, health professionals, and lifelong learners. Our recruits first enroll into an innovative on-line introductory course in Basics and Methods in Biomedical Research that uses a laboratory Tool-Kit (a lab in a box called the My Dr. ET Lab Tool-Kit) to receive the standard basics of research education, e.g., research skills, and lab techniques. The students/learners will also learn about the responsible conduct of research, research concept/design, data recording/analysis, and scientific writing/presentation. The course is followed by a 12-week hands-on research experience during the summer. The students/learners also attend workshops and seminars/conferences. The students/learners receive scholarship to cover stipends, research related expenses, and to attend a scientific conference. The scholarship allows the students/learners to gain knowledge and seize opportunities in biomedical and health-related careers. This is an ongoing program, and during the first three years of the program, fifty-one (51) students/learners have been recruited. Thirty-six (36) have completed their research training, and eighty percent (80%) of them have continued their research experiences beyond the program. The combination of carefully providing standard basics of research education and mentorship has been successful and instrumental for training these students/learners and their success in finding biomedical/health-related jobs and/or pursuing graduate/medical studies. All experiences have been positive and highly promoted. This approach has the potential to train a highly qualified workforce, change lives, enhance biomedical research, and by extension, improve national health-care.

Linking research and education: an undergraduate research apprenticeship focusing on geologic and ecological impacts of the Elwha River Restoration

NASA Astrophysics Data System (ADS)

Ogston, A. S.; Eidam, E.; Webster, K. L.; Hale, R. P.

2016-02-01

Experiential learning is becoming well-rooted in undergraduate curriculum as a means of stimulating interest in STEM fields, and of preparing students for future careers in scientific research and communication. To further these goals in coastal sciences, an intensive, research-focused course was developed at the UW Friday Harbor Labs. The course revolved around an active NSF-funded research project concerning the highly publicized Elwha River Restoration project. Between 2008 and 2014, four groups of research "apprentices" spent their academic quarter in residence at a small, coastal marine lab in a learning environment that integrated interdisciplinary lectures, workshops on data analysis and laboratory methods, and the research process from proposal to oceanographic research cruise to publication. This environment helped students gain important skills in fieldwork planning and execution, laboratory and digital data analyses, and manuscript preparation from start to finish—all while elevating their knowledge of integrated earth science topics related to a coastal restoration project. Students developed their own research proposals and pursued their individual interests within the overall research topic, thereby expanding the overall breadth of the NSF-funded research program. The topics of student interest were often beyond the researcher's expertise, which ultimately led to more interdisciplinary findings beyond the quarter-long class. This also provided opportunities for student creativity and leadership, and for collaboration with fellow course participants and with students from many other disciplines in residence at the marine lab. Tracking the outcomes of the diverse student group undertaking this program indicates that these undergraduate (and post-bac) students are generally attending graduate school at a high rate, and launching careers in education, coastal management, and other STEM fields.

Potential Follow on Experiments for the Zero Boil Off Tank Experiment

NASA Technical Reports Server (NTRS)

Chato, David; Kassemi, Mohammad

2014-01-01

Cryogenic Storage &Transfer are enabling propulsion technologies in the direct path of nearly all future human or robotic missions; It is identified by NASA as an area with greatest potential for cost saving; This proposal aims at resolving fundamental scientific issues behind the engineering development of the storage tanks; We propose to use the ISS lab to generate & collect archival scientific data:, raise our current state-of-the-art understanding of transport and phase change issues affecting the storage tank cryogenic fluid management (CFM), develop and validate state-of-the-art CFD models to innovate, optimize, and advance the future engineering designs

Putting teachers-to-be in the field and the lab: Hands-on research at the American Museum of Natural History

NASA Astrophysics Data System (ADS)

Nadeau, P. A.; Ebel, D. S.; Harlow, G. E.; Landman, N. H.; Pagnotta, A.; Sessa, J.; Shara, M.; Ustunisik, G. K.; Webster, J. D.; Blair, D.; Shumer, M.

2013-12-01

The American Museum of Natural History (AMNH) is halfway through a pilot program designed to prepare Earth Science teachers for grades 7-12 in high-needs schools in New York. The program was implemented to address a critical shortage of qualified Earth Science teachers throughout the state as well as to reach student populations that traditionally have limited science exposure and hands-on learning opportunities. This Master of Arts in Teaching is unique amongst teacher preparation programs, not only in that it is housed at a world-class research museum and places the teacher candidates in a year-long teaching residency, but also in that it accepts only students with a strong background in Earth Science via a degree in geology, meteorology, oceanography, astronomy, or a related discipline. Following a year of graduate courses in science and pedagogy, as well as teaching residencies, and only months before embarking on teaching career, candidates begin a seven-week science practicum. This exercise combines field and lab work under the tutelage of AMNH science curators and postdoctoral research fellows to provide experience with the scientific process, from field work and data collection to interpretation and public presentation of results. In the science practicum, teaching candidates begin by selecting one of four topics on which to focus their research: astrophysics, experimental petrology, mineralogy, or paleontology. An introduction to lab materials, techniques, and instrumentation is followed by two weeks in the field, both upstate and in New York City, where rocks of all types are encountered and discussed. Nights are devoted to astronomical observing and data collection to supplement the geology-oriented daytime sessions. Following the trips, candidates are back at AMNH analyzing data and samples in preparation for a short, scientific-style manuscript and presentation of results in an AGU-style talk. Three research groups have already discovered potentially publishable results from candidate-oriented lab work. Here we report on the practicum experiences of the first cohort of teacher candidates. Teacher preparation programs such as this will be increasingly valuable in coming years as a result of the recently released national Next Generation Science Standards (NGSS). These new standards shift emphasis from students memorizing scientific content to understanding the practice of science. While NGSS have not yet been adopted in New York State, they likely will be in the near future, making this program at AMNH highly relevant to the current state of science education in the United States.

Rapid quantification of live/dead lactic acid bacteria in probiotic products using high-sensitivity flow cytometry

NASA Astrophysics Data System (ADS)

He, Shengbin; Hong, Xinyi; Huang, Tianxun; Zhang, Wenqiang; Zhou, Yingxing; Wu, Lina; Yan, Xiaomei

2017-06-01

A laboratory-built high-sensitivity flow cytometer (HSFCM) was employed for the rapid and accurate detection of lactic acid bacteria (LAB) and their viability in probiotic products. LAB were stained with both the cell membrane-permeable SYTO 9 green-fluorescent nucleic acid stain and the red-fluorescent nucleic acid stain, propidium iodide, which penetrates only bacteria with compromised membranes. The side scatter and dual-color fluorescence signals of single bacteria were detected simultaneously by the HSFCM. Ultra-high temperature processing milk and skim milk spiked with Lactobacillus casei were used as the model systems for the optimization of sample pretreatment and staining. The viable LAB counts measured by the HSFCM were in good agreement with those of the plate count method, and the measured ratios between the live and dead LAB matched well with the theoretical ratios. The established method was successfully applied to the rapid quantification of live/dead LAB in yogurts and fermented milk beverages of different brands. Moreover, the concentration and viability status of LAB in ambient yogurt, a relatively new yet popular milk product in China, are also reported.

Earthquakes in Action: Incorporating Multimedia, Internet Resources, Large-scale Seismic Data, and 3-D Visualizations into Innovative Activities and Research Projects for Today's High School Students

NASA Astrophysics Data System (ADS)

Smith-Konter, B.; Jacobs, A.; Lawrence, K.; Kilb, D.

2006-12-01

The most effective means of communicating science to today's "high-tech" students is through the use of visually attractive and animated lessons, hands-on activities, and interactive Internet-based exercises. To address these needs, we have developed Earthquakes in Action, a summer high school enrichment course offered through the California State Summer School for Mathematics and Science (COSMOS) Program at the University of California, San Diego. The summer course consists of classroom lectures, lab experiments, and a final research project designed to foster geophysical innovations, technological inquiries, and effective scientific communication (http://topex.ucsd.edu/cosmos/earthquakes). Course content includes lessons on plate tectonics, seismic wave behavior, seismometer construction, fault characteristics, California seismicity, global seismic hazards, earthquake stress triggering, tsunami generation, and geodetic measurements of the Earth's crust. Students are introduced to these topics through lectures-made-fun using a range of multimedia, including computer animations, videos, and interactive 3-D visualizations. These lessons are further enforced through both hands-on lab experiments and computer-based exercises. Lab experiments included building hand-held seismometers, simulating the frictional behavior of faults using bricks and sandpaper, simulating tsunami generation in a mini-wave pool, and using the Internet to collect global earthquake data on a daily basis and map earthquake locations using a large classroom map. Students also use Internet resources like Google Earth and UNAVCO/EarthScope's Jules Verne Voyager Jr. interactive mapping tool to study Earth Science on a global scale. All computer-based exercises and experiments developed for Earthquakes in Action have been distributed to teachers participating in the 2006 Earthquake Education Workshop, hosted by the Visualization Center at Scripps Institution of Oceanography (http://siovizcenter.ucsd.edu/workshop). In addition to daily lecture and lab exercises, COSMOS students also conduct a mini-research project of their choice that uses data ranging from the 2004 Parkfield Earthquake, to Southern California seismicity, to global seismicity. Students collect seismic data from the Internet and evaluate earthquake locations, magnitudes, temporal sequence of seismic activity, active fault planes, and plate tectonic boundaries using research quality techniques. Students are given the opportunity to build 3-D visualizations of their research data sets and archive these at the SIO Visualization Center's online library, which is globally accessible to students, teachers, researchers, and the general public (http://www.siovizcenter.ucsd.edu/library.php). These student- generated visualizations have become a practical resource for not only students and teachers, but also geophysical researchers that use the visual objects as research tools to better explore and understand their data. Through Earthquakes in Action, we offer both the tools for scientific exploration and the thrills of scientific discovery, providing students with valuable knowledge, novel research experience, and a unique sense of scientific contribution.

Geology, Geochronology, and EarthScope: The EarthScope AGeS Program and a new idea for a 4D Earth Initiative

NASA Astrophysics Data System (ADS)

Flowers, R. M.; Arrowsmith, R.; Metcalf, J. R.; Rittenour, T. M.; Schoene, B.; Hole, J. A.; Pavlis, T. L.; Wagner, L. S.; Whitmeyer, S. J.; Williams, M. L.

2015-12-01

The EarthScope AGeS (Awards for Geochronology Student Research) program is a multi-year educational initiative aimed at enhancing interdisciplinary, innovative, and high-impact science by promoting training and new interactions between students, scientists, and geochronology labs at different institutions. The program offers support of up to $10,000 for graduate students to collect and interpret geochronology data that contribute to EarthScope science targets through visits to participating geochronology labs (www.earthscope.org/geochronology). The program was launched by a 2-day short course held before the 2014 National GSA meeting in Vancouver, at which 16 geochronology experts introduced 43 participants to the basic theory and applications of geochronology methods. By the first proposal submission deadline in spring 2015, 33 labs representing a broad range of techniques had joined the program by submitting lab plans that were posted on the EarthScope website. The lab plans provide information about preparation, realistic time frames for visits, and analytical costs. In the first year of the program, students submitted 47 proposals from 32 different institutions. Proposals were ranked by an independent panel, 10 were funded, and research associated with these projects is currently underway. The next proposal deadline will be held in spring 2016. The 4D-Earth initiative is an idea for a natural successor to the EarthScope program aimed at expanding the primarily 3D geophysical focus that captured a snapshot of present day North America into the 4th dimension of time (hence the connection to the prototypical AGeS program), and illuminating the crustal component that was below the resolution of much of the USArray image. Like EarthScope, the notion is that this initiative would integrate new infrastructure and usher in a new way of doing science. The overarching scientific motivation is to develop a Community Geologic Model for the 4-D Evolution of the North American continent to firmly answer long-standing questions of how the time-integrated processes of plate tectonics and surface processes produce the mantle and crustal structures we see today. A breakout session on this topic was held at the 2015 EarthScope National Meeting, and efforts are underway to solicit feedback to shape these ideas.

ERLN Technical Support for Labs

EPA Pesticide Factsheets

The Environmental Response Laboratory Network provides policies and guidance on lab and data requirements, Standardized Analytical Methods, and technical support for water and radiological sampling and analysis

e-Learning - Physics Labs

NASA Astrophysics Data System (ADS)

Mohottala, Hashini

2014-03-01

The general student population enrolled in any college level class is highly diverse. An increasing number of ``nontraditional'' students return to college and most of these students follow distance learning degree programs while engaging in their other commitments, work and family. However, those students tend to avoid taking science courses with labs, mostly because of the incapability of remotely completing the lab components in such courses. In order to address this issue, we have come across a method where introductory level physics labs can be taught remotely. In this process a lab kit with the critical lab components that can be easily accessible are conveniently packed into a box and distributed among students at the beginning of the semester. Once the students are given the apparatus they perform the experiments at home and gather data All communications with reference to the lab was done through an interactive user-friendly webpage - Wikispaces (WikiS). Students who create pages on WikiS can submit their lab write-ups, embed videos of the experiments they perform, post pictures and direct questions to the lab instructor. The students who are enrolled in the same lab can interact with each other through WikiS to discuss labs and even get assistance.

FOREWORD: Jefferson Lab: A Long Decade of Physics

NASA Astrophysics Data System (ADS)

Montgomery, Hugh

2011-04-01

Jefferson Lab Jefferson Lab was created in 1984 and started operating in about 1996. 2011 is an appropriate time to try to take a look at the results that have appeared, what has been learned, and what has been exciting for our scientific community. Rather than attempt to construct a coherent view with a single author or at least a small number, we have, instead, invited small groups of people who have been intimately involved in the work itself to make contributions. These people are accelerator experts, experimentalists and theorists, staff and users. We have, in the main, sought reviews of the actual sub-fields. The primary exception is the first paper, which sets the scene as it was, in one person's view, at the beginning of Jefferson Lab. In reviewing the material as it appeared, I was impressed by the breadth of the material. Major advances are documented from form factors to structure functions, from spectroscopy to physics beyond the standard model of nuclear and particle physics. Recognition of the part played by spin, the helicities of the beams, the polarizations of the targets, and the polarizations of final state particles, is inescapable. Access to the weak interaction amplitudes through measurements of the parity violating asymmetries has led to quantification of the strange content of the nucleon and the neutron radius of lead, and to measurements of the electroweak mixing angle. Lattice QCD calculations flourished and are setting the platform for understanding of the spectroscopy of baryons and mesons. But the star of the game was the accelerator. Its performance enabled the physics and also the use of the technology to generate a powerful free electron laser. These important pieces of Jefferson Lab physics are given their place. As the third Director of Jefferson Lab, and on behalf of the other physicists and others presently associated with the lab, I would like to express my admiration and gratitude for the efforts of the directors, chief scientists, associate directors, physicists, engineers, technicians and administrators who made it all possible. In sum, we should celebrate the science that Jefferson Lab has realized in this, its first long decade of physics. Hugh Montgomery, Director Hugh Montgomery signature

A frailty index based on laboratory deficits in community-dwelling men predicted their risk of adverse health outcomes.

PubMed

Blodgett, Joanna M; Theou, Olga; Howlett, Susan E; Wu, Frederick C W; Rockwood, Kenneth

2016-07-01

abnormal laboratory test results accumulate with age and can be common in people with few clinically detectable health deficits. A frailty index (FI) based entirely on common physiological and laboratory tests (FI-Lab) might offer pragmatic and scientific advantages compared with a clinical FI (FI-Clin). to compare the FI-Lab with the FI-Clin and to assess their individual and combined relationships with mortality and other adverse health outcomes. secondary analysis of the eight-centre, longitudinal European Male Ageing Study (EMAS) of community-dwelling men aged 40-79 at baseline. Follow-up assessment occurred 4.4 ± 0.3 (mean ± SD) years later. we constructed a 23-item FI using common laboratory tests, blood pressure and pulse (FI-Lab), compared it with a previously validated 39-item FI using self-report and performance-based measures (FI-Clin) and finally combined both FIs to create a 62-item FI-Combined. Outcomes were all-cause mortality, institutionalisation, doctor visits, medication use, self-reported health, falls and fractures. the mean FI-Lab score was 0.28 ± 0.11, the FI-Clin was 0.13 ± 0.11 and FI-Combined was 0.19 ± 0.09. Age-adjusted models demonstrated that each FI was associated with mortality [HR (CI) FI-Lab: 1.04 (1.03-1.06); FI-Clin: 1.05 (1.04-1.06); FI-Combined: 1.07 (1.06-1.09)], institutionalisation, doctor visits, medication use, self-reported health and falls. Combined in a model with FI-Clin, the FI-Lab remained independently associated with mortality, institutionalisation, doctor visits, medication use and self-reported health. the FI-Lab detected an increased risk of adverse health outcomes alone and in combination with a clinical FI; further evaluation of the feasibility of the FI-Lab as a frailty screening tool within hospital care settings is needed. © The Author 2016. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

STS-98 U.S. Lab Destiny rests in Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Viewed from the floor of the Payload Changeout Room, Destiny is inside Atlantis''' payload bay, waiting for closure of the payload bay doors. A key element in the construction of the International Space Station, Destiny is 28 feet long and weighs 16 tons. Destiny will be attached to the Unity node on the ISS using the Shuttle'''s robot arm, seen here on the left side, with the help of an elbow camera attached to the arm (near the upper end of the lab in the photo). Measurements of the elbow camera revealed only a one-inch clearance from the U.S. Lab payload, which is under review. This research and command-and-control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. Destiny will fly on STS-98, the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

Towards an easier creation of three-dimensional data for embedding into scholarly 3D PDF (Portable Document Format) files

PubMed Central

2015-01-01

The Portable Document Format (PDF) allows for embedding three-dimensional (3D) models and is therefore particularly suitable to communicate respective data, especially as regards scholarly articles. The generation of the necessary model data, however, is still challenging, especially for inexperienced users. This prevents an unrestrained proliferation of 3D PDF usage in scholarly communication. This article introduces a new solution for the creation of three of types of 3D geometry (point clouds, polylines and triangle meshes), that is based on MeVisLab, a framework for biomedical image processing. This solution enables even novice users to generate the model data files without requiring programming skills and without the need for an intensive training by simply using it as a conversion tool. Advanced users can benefit from the full capability of MeVisLab to generate and export the model data as part of an overall processing chain. Although MeVisLab is primarily designed for handling biomedical image data, the new module is not restricted to this domain. It can be used for all scientific disciplines. PMID:25780759

Towards an easier creation of three-dimensional data for embedding into scholarly 3D PDF (Portable Document Format) files.

PubMed

Newe, Axel

2015-01-01

The Portable Document Format (PDF) allows for embedding three-dimensional (3D) models and is therefore particularly suitable to communicate respective data, especially as regards scholarly articles. The generation of the necessary model data, however, is still challenging, especially for inexperienced users. This prevents an unrestrained proliferation of 3D PDF usage in scholarly communication. This article introduces a new solution for the creation of three of types of 3D geometry (point clouds, polylines and triangle meshes), that is based on MeVisLab, a framework for biomedical image processing. This solution enables even novice users to generate the model data files without requiring programming skills and without the need for an intensive training by simply using it as a conversion tool. Advanced users can benefit from the full capability of MeVisLab to generate and export the model data as part of an overall processing chain. Although MeVisLab is primarily designed for handling biomedical image data, the new module is not restricted to this domain. It can be used for all scientific disciplines.

The state of RT-quantitative PCR: firsthand observations of implementation of minimum information for the publication of quantitative real-time PCR experiments (MIQE).

PubMed

Taylor, Sean C; Mrkusich, Eli M

2014-01-01

In the past decade, the techniques of quantitative PCR (qPCR) and reverse transcription (RT)-qPCR have become accessible to virtually all research labs, producing valuable data for peer-reviewed publications and supporting exciting research conclusions. However, the experimental design and validation processes applied to the associated projects are the result of historical biases adopted by individual labs that have evolved and changed since the inception of the techniques and associated technologies. This has resulted in wide variability in the quality, reproducibility and interpretability of published data as a direct result of how each lab has designed their RT-qPCR experiments. The 'minimum information for the publication of quantitative real-time PCR experiments' (MIQE) was published to provide the scientific community with a consistent workflow and key considerations to perform qPCR experiments. We use specific examples to highlight the serious negative ramifications for data quality when the MIQE guidelines are not applied and include a summary of good and poor practices for RT-qPCR. © 2013 S. Karger AG, Basel.

From Bell Labs to Silicon Valley: A Saga of Technology Transfer, 1954-1961

NASA Astrophysics Data System (ADS)

Riordan, Michael

2009-03-01

Although Bell Telephone Laboratories invented the transistor and developed most of the associated semiconductor technology, the integrated circuit or microchip emerged elsewhere--at Texas Instruments and Fairchild Semiconductor Company. I recount how the silicon technology required to make microchips possible was first developed at Bell Labs in the mid-1950s. Much of it reached the San Francisco Bay Area when transistor pioneer William Shockley left Bell Labs in 1955 to establish the Shockley Semiconductor Laboratory in Mountain View, hiring a team of engineers and scientists to develop and manufacture transistors and related semiconductor devices. But eight of them--including Gordon Moore and Robert Noyce, eventually the co-founders of Intel--resigned en masse in September 1957 to start Fairchild, bringing with them the scientific and technological expertise they had acquired and further developed at Shockley's firm. This event marked the birth of Silicon Valley, both technologically and culturally. By March 1961 the company was marketing its Micrologic integrated circuits, the first commercial silicon microchips, based on the planar processing technique developed at Fairchild by Jean Hoerni.

Meeting Report of the 33rd Annual Meeting of the Academy of Surgical Research: Summary of Presentations, Labs, and Workshops, Focusing on Experimental Surgery, Las Vegas, NV, October 4-6, 2017.

PubMed

Graham, Melanie L; Ziegelhofer, Tracy; Ehrmann, Jon

2018-04-11

The 33rd Annual Meeting of the Academy of Surgical Research was held from October 4 to 6, 2017 in Las Vegas, Nevada. The meeting welcomed >160 participants from 27 different states and five countries representing the organization's diverse membership of technicians, veterinarians, medical doctors, and biomedical researchers. The Academy's annual meeting is focused on promoting the advancement of professional and academic standards, education, and research related to the art and science of experimental surgery. Presentations included four invited keynote speakers and 30 selected lectures and posters. A primary strength of the meeting was that lectures were complimented with practical sessions that included four wet lab and two dry lab half-day courses. Likewise, participants were brought together in workshops emphasizing research workflow from starting experimental design to readying results for publication. In this report, we present the highlights from this meeting and some selected abstracts that illustrate the diverse scientific expertise of the Academy and progress in surgical research.

Designing a solution to enable agency-academic scientific collaboration for disasters

USGS Publications Warehouse

Mease, Lindley A.; Gibbs-Plessl, Theodora; Erickson, Ashley; Ludwig, Kristin A.; Reddy, Christopher M.; Lubchenco, Jane

2017-01-01

As large-scale environmental disasters become increasingly frequent and more severe globally, people and organizations that prepare for and respond to these crises need efficient and effective ways to integrate sound science into their decision making. Experience has shown that integrating nongovernmental scientific expertise into disaster decision making can improve the quality of the response, and is most effective if the integration occurs before, during, and after a crisis, not just during a crisis. However, collaboration between academic, government, and industry scientists, decision makers, and responders is frequently difficult because of cultural differences, misaligned incentives, time pressures, and legal constraints. Our study addressed this challenge by using the Deep Change Method, a design methodology developed by Stanford ChangeLabs, which combines human-centered design, systems analysis, and behavioral psychology. We investigated underlying needs and motivations of government agency staff and academic scientists, mapped the root causes underlying the relationship failures between these two communities based on their experiences, and identified leverage points for shifting deeply rooted perceptions that impede collaboration. We found that building trust and creating mutual value between multiple stakeholders before crises occur is likely to increase the effectiveness of problem solving. We propose a solution, the Science Action Network, which is designed to address barriers to scientific collaboration by providing new mechanisms to build and improve trust and communication between government administrators and scientists, industry representatives, and academic scientists. The Science Action Network has the potential to ensure cross-disaster preparedness and science-based decision making through novel partnerships and scientific coordination.

Personalized Online Learning Labs and Face-To-Face Teaching in First-Year College English Courses

ERIC Educational Resources Information Center

Sizemore, Mary L.

2017-01-01

The purpose of this two-phase, explanatory mixed methods study was to understand the benefits of teaching grammar from three different learning methods: face-to-face, online personalized learning lab and a blended learning method. The study obtained quantitative results from a pre and post-tests, a general survey and writing assignment rubrics…

STS-98 payload U.S. Lab Destiny is moved into Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Workers in the Payload Changeout Room begin moving the U.S. Lab Destiny to the orbiter'''s payload bay. The PCR is the enclosed, environmentally controlled portion of the rotating service structure that supports payload delivery at the launch pad and vertical installation in the orbiter payload bay. Destiny, a key element in the construction of the International Space Station, is 28 feet long and weighs 16 tons. This research and command-and- control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. STS-98 is the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

Inside the U.S. Lab, called 'Destiny,' which is in the Space Station Processing Facility, U.S. Rep. Dave Weldon (right) looks over equipment. In the background (center) is Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Insights: Future of the national laboratories. National Renewable Energy Laboratory. [The future of the National Renewable Energy (Sources) Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunderman, D.

Psychologists tell us that people are born with certain personality traits, such as shyness or boldness, which their environment can encourage, subdue, or even alter. National labs have somewhat similar characteristics. They were created for particular missions and staffed by people who built organizations in which those missions could be fulfilled. As a result, the Department of Energy's (DOE) national labs are among the world's finest repositories of technology and scientific talent, especially in the fields of defense, nuclear weapons, nuclear power, and basic energy. Sunderman, director of the National Renewable Energy Laboratory, discusses the history of the laboratory andmore » its place in the future, both in terms of technologies and nurturing.« less

Guitars, Keyboards, Strobes, and Motors -- From Vibrational Motion to Active Research

NASA Astrophysics Data System (ADS)

Tagg, Randall; Carlson, John; Asadi-Zeydabadi, Masoud; Busley, Brad; Law-Balding, Katie; Juengel, Mattea

2013-01-01

Physics First is offered to ninth graders at high schools in Aurora, CO. A unique new asset of this school system is an embedded research lab called the "Innovation Hyperlab." The goal of the lab is to connect secondary school teaching to ongoing university scientific research, supporting the school district's aim to create opportunities to integrate P-20 (preschool to graduate school) learning. This paper is an example of how we create research connections in the context of introductory physics lessons on vibrations and waves. Key to the process is the use of several different types of technical resources, hence the name "hyperlab." Students learn many practical experimental techniques, reinforcing their knowledge of fundamentals and preparing them to work effectively on open-ended research or engineering projects.

U.S. Rep. Dave Weldon outside the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility, U.S. Rep Dave Weldon (at left) looks at the U.S. Lab, called Destiny. With him are Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, Dana Gartzke, the congressman's chief of staffm and Boeing workers. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Superomniphobic Surfaces for Military Applications: Nano- and Micro-Fabrication Methods: Year Two Report

DTIC Science & Technology

2011-12-01

versatility has allowed for an additional investigation on the use of the SH coating for Lab on Chip ( LOC ) and Lab on Paper (LOP) applications by spraying the...Lab On Chip ( LOC ) and Lab On Paper (LOP) devices. The study concluded that the newly developed SH coating formulation can withstand prolonged...Microscope (Carl Zeiss LEO 1430). Before SEM imaging, a gold layer of 10 nm was deposited on the sample surface. Care was taken such that CSM, SEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haber, Carl

Summer Lecture Series 2006: Physicist Carl Haber and colleagues have found a way to digitize century-old recordings believed to be unplayable, and as a result, some of the music and spoken word recordings in the Library of Congress collection may spring back to life. Learn how basic scientific research done at Berkeley Lab may yield results of benefit in other areas of science and culture. Series: "Lawrence Berkeley National Laboratory Summer Lecture Series"

US-Europe Workshop on Impact of Multifunctionality on Damage Evolution in Composite Materials

DTIC Science & Technology

2015-09-01

Inventions (DD882) Scientific Progress See Attachment Technology Transfer Not applicable UNIVERSITY OF ILLINOIS AEROSPACE ENGINEERING...Composite Materials PI: Ioannis Chasiotis Aerospace Engineering University of Illinois at Urbana-Champaign Talbot Lab, 104 S. Wright Street, Urbana, IL...focused on the current state of corporate research in the aerospace industry which is a major potential adopter of multifunctional composites. The two

Modeling the Water Balloon Slingshot

NASA Astrophysics Data System (ADS)

Bousquet, Benjamin D.; Figura, Charles C.

2013-01-01

In the introductory physics courses at Wartburg College, we have been working to create a lab experience focused on the scientific process itself rather than verification of physical laws presented in the classroom or textbook. To this end, we have developed a number of open-ended modeling exercises suitable for a variety of learning environments, from non-science major classes to algebra-based and calculus-based introductory physics classes.

Big Data Smart Socket (BDSS): a system that abstracts data transfer habits from end users.

PubMed

Watts, Nicholas A; Feltus, Frank A

2017-02-15

The ability to centralize and store data for long periods on an end user's computational resources is increasingly difficult for many scientific disciplines. For example, genomics data is increasingly large and distributed, and the data needs to be moved into workflow execution sites ranging from lab workstations to the cloud. However, the typical user is not always informed on emerging network technology or the most efficient methods to move and share data. Thus, the user defaults to using inefficient methods for transfer across the commercial internet. To accelerate large data transfer, we created a tool called the Big Data Smart Socket (BDSS) that abstracts data transfer methodology from the user. The user provides BDSS with a manifest of datasets stored in a remote storage repository. BDSS then queries a metadata repository for curated data transfer mechanisms and optimal path to move each of the files in the manifest to the site of workflow execution. BDSS functions as a standalone tool or can be directly integrated into a computational workflow such as provided by the Galaxy Project. To demonstrate applicability, we use BDSS within a biological context, although it is applicable to any scientific domain. BDSS is available under version 2 of the GNU General Public License at https://github.com/feltus/BDSS . ffeltus@clemson.edu. © The Author 2016. Published by Oxford University Press.

Big Data Smart Socket (BDSS): a system that abstracts data transfer habits from end users

PubMed Central

Watts, Nicholas A.

2017-01-01

Motivation: The ability to centralize and store data for long periods on an end user’s computational resources is increasingly difficult for many scientific disciplines. For example, genomics data is increasingly large and distributed, and the data needs to be moved into workflow execution sites ranging from lab workstations to the cloud. However, the typical user is not always informed on emerging network technology or the most efficient methods to move and share data. Thus, the user defaults to using inefficient methods for transfer across the commercial internet. Results: To accelerate large data transfer, we created a tool called the Big Data Smart Socket (BDSS) that abstracts data transfer methodology from the user. The user provides BDSS with a manifest of datasets stored in a remote storage repository. BDSS then queries a metadata repository for curated data transfer mechanisms and optimal path to move each of the files in the manifest to the site of workflow execution. BDSS functions as a standalone tool or can be directly integrated into a computational workflow such as provided by the Galaxy Project. To demonstrate applicability, we use BDSS within a biological context, although it is applicable to any scientific domain. Availability and Implementation: BDSS is available under version 2 of the GNU General Public License at https://github.com/feltus/BDSS. Contact: ffeltus@clemson.edu PMID:27797780

A future for systems and computational neuroscience in France?

PubMed

Faugeras, Olivier; Frégnac, Yves; Samuelides, Manuel

2007-01-01

This special issue of the Journal of Physiology, Paris, is an outcome of NeuroComp'06, the first French conference in Computational Neuroscience. The preparation for this conference, held at Pont-à-Mousson in October 2006, was accompanied by a survey which has resulted in an up-to-date inventory of human resources and labs in France concerned with this emerging new field of research (see team directory in http://neurocomp.risc.cnrs.fr/). This thematic JPP issue gathers some of the key scientific presentations made on the occasion of this first interdisciplinary meeting, which should soon become recognized as a yearly national conference representative of a new scientific community. The present introductory paper presents the general scientific context of the conference and reviews some of the historical and conceptual foundations of Systems and Computational Neuroscience in France.

NASA's Ship-Aircraft Bio-Optical Research (SABOR)

NASA Image and Video Library

2014-08-25

What's in the Water? Robert Foster, of the City College of New York, filters seawater on July 23, 2414, for chlorophyll analysis in a lab on the R/V Endeavor. NASA's Ship-Aircraft Bio-Optical Research (SABOR) experiment is a coordinated ship and aircraft observation campaign off the Atlantic coast of the United States, an effort to advance space-based capabilities for monitoring microscopic plants that form the base of the marine food chain. Read more: 1.usa.gov/WWRVzj Credit: NASA/SABOR/Wayne Slade, Sequoia Scientific..NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Optimizing students’ scientific communication skills through higher order thinking virtual laboratory (HOTVL)

NASA Astrophysics Data System (ADS)

Sapriadil, S.; Setiawan, A.; Suhandi, A.; Malik, A.; Safitri, D.; Lisdiani, S. A. S.; Hermita, N.

2018-05-01

Communication skill is one skill that is very needed in this 21st century. Preparing and teaching this skill in teaching physics is relatively important. The focus of this research is to optimizing of students’ scientific communication skills after the applied higher order thinking virtual laboratory (HOTVL) on topic electric circuit. This research then employed experimental study particularly posttest-only control group design. The subject in this research involved thirty senior high school students which were taken using purposive sampling. A sample of seventy (70) students participated in the research. An equivalent number of thirty five (35) students were assigned to the control and experimental group. The results of this study found that students using higher order thinking virtual laboratory (HOTVL) in laboratory activities had higher scientific communication skills than students who used the verification virtual lab.

Simple and inexpensive hardware and software method to measure volume changes in Xenopus oocytes expressing aquaporins.

PubMed

Dorr, Ricardo; Ozu, Marcelo; Parisi, Mario

2007-04-15

Water channels (aquaporins) family members have been identified in central nervous system cells. A classic method to measure membrane water permeability and its regulation is to capture and analyse images of Xenopus laevis oocytes expressing them. Laboratories dedicated to the analysis of motion images usually have powerful equipment valued in thousands of dollars. However, some scientists consider that new approaches are needed to reduce costs in scientific labs, especially in developing countries. The objective of this work is to share a very low-cost hardware and software setup based on a well-selected webcam, a hand-made adapter to a microscope and the use of free software to measure membrane water permeability in Xenopus oocytes. One of the main purposes of this setup is to maintain a high level of quality in images obtained at brief intervals (shorter than 70 ms). The presented setup helps to economize without sacrificing image analysis requirements.

Design of pressure-driven microfluidic networks using electric circuit analogy.

PubMed

Oh, Kwang W; Lee, Kangsun; Ahn, Byungwook; Furlani, Edward P

2012-02-07

This article reviews the application of electric circuit methods for the analysis of pressure-driven microfluidic networks with an emphasis on concentration- and flow-dependent systems. The application of circuit methods to microfluidics is based on the analogous behaviour of hydraulic and electric circuits with correlations of pressure to voltage, volumetric flow rate to current, and hydraulic to electric resistance. Circuit analysis enables rapid predictions of pressure-driven laminar flow in microchannels and is very useful for designing complex microfluidic networks in advance of fabrication. This article provides a comprehensive overview of the physics of pressure-driven laminar flow, the formal analogy between electric and hydraulic circuits, applications of circuit theory to microfluidic network-based devices, recent development and applications of concentration- and flow-dependent microfluidic networks, and promising future applications. The lab-on-a-chip (LOC) and microfluidics community will gain insightful ideas and practical design strategies for developing unique microfluidic network-based devices to address a broad range of biological, chemical, pharmaceutical, and other scientific and technical challenges.

On-demand Droplet Manipulation via Triboelectrification

NASA Astrophysics Data System (ADS)

Wang, Wei; Vahabi, Hamed; Cackovic, Matthew; Jiang, Rui; Kota, Arun

2017-11-01

Controlled manipulation of liquid droplets has attracted tremendous interest across different scientific fields over the past two decades. To date, a variety of external stimuli-mediated methods such as magnetic field, electric field, and light have been developed for manipulating droplets on surfaces. However, these methods usually have drawbacks such as complex fabrication of manipulation platform, low droplet motility, expensive actuation system and lack of precise control. In this work, we demonstrate the controlled manipulation of liquid droplet with both high (e.g., water) and low (e.g., n-hexadecane) dielectric strengths on a smooth, slippery surface via triboelectric effect. Our highly simple, facile and portable methodology enables on-demand, precise manipulation of droplets using solely the electrostatic attraction or repulsion force, which is exerted on the droplet by a simple charged actuator (e.g., Teflon film). We envision that our triboelectric effect enabled droplet manipulation methodology will open a new avenue for droplet based lab-on-a-chip systems, energy harvesting devices and biomedical applications.

Progress in Multi-Disciplinary Data Life Cycle Management

NASA Astrophysics Data System (ADS)

Jung, C.; Gasthuber, M.; Giesler, A.; Hardt, M.; Meyer, J.; Prabhune, A.; Rigoll, F.; Schwarz, K.; Streit, A.

2015-12-01

Modern science is most often driven by data. Improvements in state-of-the-art technologies and methods in many scientific disciplines lead not only to increasing data rates, but also to the need to improve or even completely overhaul their data life cycle management. Communities usually face two kinds of challenges: generic ones like federated authorization and authentication infrastructures and data preservation, and ones that are specific to their community and their respective data life cycle. In practice, the specific requirements often hinder the use of generic tools and methods. The German Helmholtz Association project ’’Large-Scale Data Management and Analysis” (LSDMA) addresses both challenges: its five Data Life Cycle Labs (DLCLs) closely collaborate with communities in joint research and development to optimize the communities data life cycle management, while its Data Services Integration Team (DSIT) provides generic data tools and services. We present most recent developments and results from the DLCLs covering communities ranging from heavy ion physics and photon science to high-throughput microscopy, and from DSIT.

Strain-specific detection of orally administered canine jejunum-dominated Lactobacillus acidophilus LAB20 in dog faeces by real-time PCR targeted to the novel surface layer protein.

PubMed

Tang, Y; Saris, P E J

2013-10-01

Lactobacillus acidophilus LAB20 has potential to be a probiotic strain because it can be present at high numbers in the jejunum of dog. To specifically detect LAB20 from dog faecal samples, a real-time PCR protocol was developed targeting the novel surface (S) layer protein gene of LAB20. The presence of S-layer protein was verified by N-terminal sequencing of the approximately 50-kDa major band from SDS-PAGE gel. The corresponding S-layer gene was amplified by inverse PCR using homology to known S-layers and sequenced. This novel S-layer protein has low sequence similarity to other S-layer proteins in the N-terminal region (32-211 aa, 7-39%). This enabled designing strain-specific PCR primers. The primer set was utilized to study intestinal persistence of LAB20 in dog that was fed with LAB20 fermented milk for 5 days. The results showed that LAB20 can be detected from dog faecal sample after 6 weeks with 10(4·53)  DNA copies g(-1) postadministration. It suggested that LAB20 could be a good candidate to study the mechanism behind its persistence and dominance in dog intestine and maybe utilize it as a probiotic for canine. A real-time PCR method was developed to detect Lactobacillus acidophilus LAB20, a strain that was previously found dominant in canine gastrointestinal (GI) tract. The quantitative detection was based on targeting to variation region of a novel S-layer protein found in LAB20, allowing to specifically enumerate LAB20 from dog faeces. The results showed that the real-time PCR method was sensitive enough to be used in later intervention studies. Interestingly, LAB20 was found to persist in dog GI tract for 6 weeks. Therefore, LAB20 could be a good candidate to study its colonization and potentially utilize as a canine probiotic. © 2013 The Society for Applied Microbiology.

Librarians and Scientists Partner to Address Data Management: Taking Collaboration to the Next Level

PubMed Central

Medina-Smith, Andrea; Tryka, Kimberly A.; Silcox, Barbara P.; Hanisch, Robert J.

2016-01-01

Purpose This study looks at the changing way in which the Information Services Office (ISO) at the National Institute of Standards and Technology (NIST) provides services to NIST scientific and technical staff throughout their research and publishing cycles. These services include the more traditional services of a research library as well as publishing NIST technical reports and The Journal of Research of NIST, and preserving and exhibiting scientific instruments and other artifacts. ISO has always prided itself on having a close relationship with its customers, providing a high level of service, and developing new services to stay in front of NIST researcher needs. Through a concerted, strategic effort since the late 1990s, ISO has developed and promoted relationships with its key customers through its Lab Liaison Program. Design/methodology/approach This paper discusses the relationship ISO has developed with the Office of Data and Informatics (ODI), how this relationship was forged, and how this collaboration will serve as a model for working with the other labs and programs at NIST. It will also discuss the risks and opportunities of this new collaborative service model, how ISO positioned itself to become an equal partner with ODI in the exploration of solutions to data management issues, and the benefits of the relationship from ODI's perspective. Findings A pattern of strategic changes to the services and activities offered by the Lab Liaison program has put ISO in the position to collaborate as peers with researchers at NIST. Originality/value This study provides an overview of how ISO made strategic decisions to incorporate non-traditional services to support data management at NIST. PMID:27891247

GeneLab: Multi-Omics Investigation of Rodent Research-1 Bio-Banked Tissues

NASA Technical Reports Server (NTRS)

Lai, San-Huei; Boyko, Valery; Chakravarty, Kaushik; Chen, Rick; Dueck, Sandra; Berrios, Daniel C.; Fogle, Homer; Marcu, Oana; Timucin, Linda; Reinsch, Sigrid;

Stream piracy in the Black Hills: A geomorphology lab exercise

USGS Publications Warehouse

Zaprowski, B.J.; Evenson, E.B.; Epstein, J.B.

2002-01-01

The Black Hills of South Dakota exhibits many fine examples of stream piracy that are very suitable for teaching geomorphology lab exercises. This lab goes beyond standard topographic map interpretation by using geologic maps, well logs, gravel provenance and other types of data to teach students about stream piracy. Using a step-by-step method in which the lab exercises ramp up in difficulty, students hone their skills in deductive reasoning and data assimilation. The first exercises deal with the identification of stream piracy at a variety of spatial scales and the lab culminates with an exercise on landscape evolution and drainage rearrangement.

Open semantic annotation of scientific publications using DOMEO

PubMed Central

2012-01-01

Background Our group has developed a useful shared software framework for performing, versioning, sharing and viewing Web annotations of a number of kinds, using an open representation model. Methods The Domeo Annotation Tool was developed in tandem with this open model, the Annotation Ontology (AO). Development of both the Annotation Framework and the open model was driven by requirements of several different types of alpha users, including bench scientists and biomedical curators from university research labs, online scientific communities, publishing and pharmaceutical companies. Several use cases were incrementally implemented by the toolkit. These use cases in biomedical communications include personal note-taking, group document annotation, semantic tagging, claim-evidence-context extraction, reagent tagging, and curation of textmining results from entity extraction algorithms. Results We report on the Domeo user interface here. Domeo has been deployed in beta release as part of the NIH Neuroscience Information Framework (NIF, http://www.neuinfo.org) and is scheduled for production deployment in the NIF’s next full release. Future papers will describe other aspects of this work in detail, including Annotation Framework Services and components for integrating with external textmining services, such as the NCBO Annotator web service, and with other textmining applications using the Apache UIMA framework. PMID:22541592

A Study of Concept Mapping as an Instructional Intervention in an Undergraduate General Chemistry Calorimetry Laboratory

NASA Astrophysics Data System (ADS)

Stroud, Mary W.

This investigation, rooted in both chemistry and education, considers outcomes occurring in a small-scale study in which concept mapping was used as an instructional intervention in an undergraduate calorimetry laboratory. A quasi-experimental, multiple-methods approach was employed since the research questions posed in this study warranted the use of both qualitative and quantitative perspectives and evaluations. For the intervention group of students, a convenience sample, post-lab concept maps, written discussions, quiz responses and learning surveys were characterized and evaluated. Archived quiz responses for non-intervention students were also analyzed for comparison. Students uniquely constructed individual concept maps containing incorrect, conceptually correct and "scientifically thin" calorimetry characterizations. Students more greatly emphasized mathematical relationships and equations utilized during the calorimetry experiment; the meaning of calorimetry concepts was demonstrated to a lesser extent.

Changing Images of the Inclined Plane: A Case Study of a Revolution in American Science Education

NASA Astrophysics Data System (ADS)

Turner, Steven C.

2012-02-01

Between 1880 and 1920 the way science was taught in American High Schools changed dramatically. The old "lecture/demonstration" method, where information was presented to essentially passive students, was replaced by the "laboratory" method, where students performed their own experiments in specially constructed student laboratories. National leadership in education was generally weak during this period, and the new method required significant investments by the schools, but within a few decades American science education was rapidly and completely transformed. Previous studies of this fundamental change have concentrated on the activities of organizations like the NEA, the Bureau of Education and a few major universities, but the way in which these groups were able to effect actual changes in classroom practice is not completely clear. This article attempts to broaden the existing narrative by integrating the rich and largely ignored material culture of science education—such things as textbooks, lab manuals, student notebooks, science teaching instruments and scientific instrument catalogs. Surprisingly, much of this story can be seen in changes to the depiction of a single, venerable and otherwise unremarkable teaching instrument: the inclined plane.

AirLab: a cloud-based platform to manage and share antibody-based single-cell research.

PubMed

Catena, Raúl; Özcan, Alaz; Jacobs, Andrea; Chevrier, Stephane; Bodenmiller, Bernd

2016-06-29

Single-cell analysis technologies are essential tools in research and clinical diagnostics. These methods include flow cytometry, mass cytometry, and other microfluidics-based technologies. Most laboratories that employ these methods maintain large repositories of antibodies. These ever-growing collections of antibodies, their multiple conjugates, and the large amounts of data generated in assays using specific antibodies and conditions makes a dedicated software solution necessary. We have developed AirLab, a cloud-based tool with web and mobile interfaces, for the organization of these data. AirLab streamlines the processes of antibody purchase, organization, and storage, antibody panel creation, results logging, and antibody validation data sharing and distribution. Furthermore, AirLab enables inventory of other laboratory stocks, such as primers or clinical samples, through user-controlled customization. Thus, AirLab is a mobile-powered and flexible tool that harnesses the capabilities of mobile tools and cloud-based technology to facilitate inventory and sharing of antibody and sample collections and associated validation data.

Deriving Childhood Temperament Measures from Emotion-eliciting Behavioral Episodes: Scale Construction and Initial Validation

PubMed Central

Gagne, Jeffrey R.; Van Hulle, Carol A.; Aksan, Nazan; Essex, Marilyn J.; Goldsmith, H. Hill

2010-01-01

The authors describe the development and initial validation of a home-based version of the Laboratory Temperament Assessment Battery (Lab-TAB), which was designed to assess childhood temperament using a comprehensive series of emotion-eliciting behavioral episodes. This paper provides researchers with general guidelines for assessing specific behaviors using the Lab-TAB and for forming behavioral composites that correspond to commonly researched temperament dimensions. We used mother ratings and independent post-visit observer ratings to provide validity evidence in a community sample of 4.5 year-old children. 12 Lab-TAB behavioral episodes were employed, yielding 24 within-episode temperament components that collapsed into 9 higher-level composites (Anger, Sadness, Fear, Shyness, Positive Expression, Approach, Active Engagement, Persistence, and Inhibitory Control). These dimensions of temperament are similar to those found in questionnaire-based assessments. Correlations among the 9 composites were low to moderate, suggesting relative independence. As expected, agreement between Lab-TAB measures and post-visit observer ratings was stronger than agreement between the Lab-TAB and mother questionnaire. However, for Active Engagement and Shyness, mother ratings did predict child behavior in the Lab-TAB quite well. Findings demonstrate the feasibility of emotion-eliciting temperament assessment methodologies, suggest appropriate methods for data aggregation into trait-level constructs, and set some expectations for associations between Lab-TAB dimensions and the degree of cross-method convergence between the Lab-TAB and other commonly used temperament assessments. PMID:21480723

Making the State of the Art the Classroom Benchmark: A Climate Change Curriculum Based on Synthesis Science

NASA Astrophysics Data System (ADS)

Nicholas, K. A.

2014-12-01

A hallmark of science in the Anthropocene is the increasing use of synthesis efforts to distill ever-growing data into the best available scientific knowledge. Thousands of scientists contribute substantial amounts of time towards these efforts, with the aim of producing authoritative work as a basis for informing both further research priorities and policy decisions. Organizations such as the IPCC are increasing their efforts to disseminate their scientific findings to broader audiences, for example, using text and video summaries targeted for policymakers. However, the results of such synthesis efforts have rarely been disseminated further back in the pipeline, in the classrooms where scientific literacy is shaped. Here, I will describe an emerging initiative to develop a program to translate state-of-the-art scientific synthesis findings into a modular, flexible climate change curriculum. This initiative is envisioned to compliment rather than compete with existing curriculum development efforts. Examples from innovation labs in healthcare delivery and other fields will be used to demonstrate a model for how a small, interdisciplinary team of early-career experts can use their content and pedagogical knowledge to transform synthesis results into ready-to-use teaching materials. The benefits of such a curriculum include improved student learning through constructive alignment of thoughtfully designed teaching and learning activities and assessment activities to promote intended learning outcomes, as well as the real-world illustration of the method of scientific inquiry applied to socially relevant problems. The curriculum can also improve teaching experiences through increased efficiency in course preparation, and in sharing best practices with participating colleagues. Initial scoping will examine the needs of university teachers of climate change courses as the constituents of this curriculum, and possible support models to mainstream such efforts. Ultimately, using scientific syntheses as the basis for university curricula would help close the gap between research and classroom learning, promote increased scientific understanding, and help ensure that the resources devoted to scientific synthesis efforts are translated to broader benefits for society.

Of Mice and Meth: A New Media-Based Neuropsychopharmacology Lab to Teach Research Methods

ERIC Educational Resources Information Center

Hatch, Daniel L.; Zschau, Tony; Hays, Arthur; McAllister, Kristin; Harrison, Michelle; Cate, Kelly L.; Shanks, Ryan A.; Lloyd, Steven A.

2014-01-01

This article describes an innovative neuropsychopharmacology laboratory that can be incorporated into any research methods class. The lab consists of a set of interconnected modules centered on observations of methamphetamine-induced behavioral changes in mice and is designed to provide students with an opportunity to acquire basic skills…

Online Statistics Labs in MSW Research Methods Courses: Reducing Reluctance toward Statistics

ERIC Educational Resources Information Center

Elliott, William; Choi, Eunhee; Friedline, Terri

2013-01-01

This article presents results from an evaluation of an online statistics lab as part of a foundations research methods course for master's-level social work students. The article discusses factors that contribute to an environment in social work that fosters attitudes of reluctance toward learning and teaching statistics in research methods…

Constructing a LabVIEW-Controlled High-Performance Liquid Chromatography (HPLC) System: An Undergraduate Instrumental Methods Exercise

ERIC Educational Resources Information Center

Smith, Eugene T.; Hill, Marc

2011-01-01

In this laboratory exercise, students develop a LabVIEW-controlled high-performance liquid chromatography system utilizing a data acquisition device, two pumps, a detector, and fraction collector. The programming experience involves a variety of methods for interface communication, including serial control, analog-to-digital conversion, and…

TReacLab: An object-oriented implementation of non-intrusive splitting methods to couple independent transport and geochemical software

NASA Astrophysics Data System (ADS)

Jara, Daniel; de Dreuzy, Jean-Raynald; Cochepin, Benoit

2017-12-01

Reactive transport modeling contributes to understand geophysical and geochemical processes in subsurface environments. Operator splitting methods have been proposed as non-intrusive coupling techniques that optimize the use of existing chemistry and transport codes. In this spirit, we propose a coupler relying on external geochemical and transport codes with appropriate operator segmentation that enables possible developments of additional splitting methods. We provide an object-oriented implementation in TReacLab developed in the MATLAB environment in a free open source frame with an accessible repository. TReacLab contains classical coupling methods, template interfaces and calling functions for two classical transport and reactive software (PHREEQC and COMSOL). It is tested on four classical benchmarks with homogeneous and heterogeneous reactions at equilibrium or kinetically-controlled. We show that full decoupling to the implementation level has a cost in terms of accuracy compared to more integrated and optimized codes. Use of non-intrusive implementations like TReacLab are still justified for coupling independent transport and chemical software at a minimal development effort but should be systematically and carefully assessed.

How Do Learning Outcomes, Assessments and Student Engagement in a Fully Online Geoscience Laboratory Compare to Those Of The Original Hands-on Exercise?

NASA Astrophysics Data System (ADS)

Jones, F. M.

2015-12-01

In a third year geoscience elective for BSc majors, we adapted several active f2f learning strategies for an equivalent fully online version of the course. In particular, we converted a hands-on laboratory including analysis and interpretation of hand-specimens, sketching results and peer-to-peer discussion of scientific implications. This study compares learning outcomes in both formats and describes resources that make engaging, effective and efficient learning experiences for large classes in an asynchronous online environment. Our two hypotheses are: 1) a hands-on geology lab exercise can be converted for efficient fully online use without sacrificing feedback and assessment opportunities; 2) students find either the f2f or DE versions equally effective and enjoyable as learning experiences. Key components are an authentic context, interactive resources including sketching, strategies that enable efficient assessment and feedback on solo and group work, and asynchronous yet productive interaction with peers. Students in the f2f class handle real rock and fossil specimens, work with peers in the lab and classroom, and deliver most results including annotated figures on paper. DE students complete identical tasks using interactive high resolution figures and videos of specimens. Solo work is first delivered for automated assessment and feedback, then students engage asynchronously in small groups to improve results and discuss implications. Chronostratigraphy and other interpretations are sketched on prepared template images using a simple open-source sketching app that ensures equal access and consistent results that are efficient to assess by peers and instructors. Learning outcomes based on subsequent quizzes, sketches, and lab results (paper for f2f students and automated data entry for DE students), show that f2f and online students demonstrate knowledge and scientific interpretations of comparable quality. Effective engagement and group work are demonstrated for f2f students using video and survey data, and for DE students using learning management system tracking data and similar survey data. Finally, these initiatives are shown to be scalable to classes of many students by comparing the time required for instructors to run and grade the lab in both settings.

Design of inquiry-oriented science labs: impacts on students' attitudes

NASA Astrophysics Data System (ADS)

Baseya, J. M.; Francis, C. D.

2011-11-01

Background: Changes in lab style can lead to differences in learning. Two inquiry-oriented lab styles are guided inquiry (GI) and problem-based (PB). Students' attitudes towards lab are important to consider when choosing between GI and PB styles during curriculum design. Purpose: We examined the degree to which lab experiences are explained by a GI or a PB lab style vs. students' attitudes towards specific aspects of the experience, reflected by perceived excitement (exc), difficulty (dif), time efficiency (eff) and association between lab and lecture material (help). Sample: Approximately 1000 students attending first-semester, college biology lab for science majors at the University of Colorado at Boulder, USA, participated in the study. Design and method: In 2007, two labs were run as GI and one as PB. Formats were switched in 2008. Attitudes were assessed with a post-semester survey. Results: Only the four attitude variables (not lab style) had a strong relationship with overall lab rating which was most strongly related to exc, followed by dif and help/eff. Dif and eff had the greatest influence on attitudes for or against GI vs. PB labs, and help and exc had little influence on a GI vs. a PB lab. Also, when dif was low, students' attitudes were not significantly different between PB and GI labs, but when dif was high, students' significantly rated GI labs higher than PB labs. Conclusions: Students' attitudes towards lab are more dependent on specific aspects of the experience than on lab style. Changes in GI vs. PB lab styles primarily influence dif and eff rather than exc and help. Dif may be an important factor to consider when implementing a lab in the PB vs. the GI format. It might be good to go with a GI when dif is high and a PB when dif is low.

Assessing the Impact of a Virtual Lab in an Allied Health Program.

PubMed

Kay, Robin; Goulding, Helene; Li, Jia

2018-01-01

Competency-based education in health care requires rigorous standards to ensure professional proficiency. Demonstrating competency in hands-on laboratories calls for effective preparation, knowledge, and experience, all of which can be difficult to achieve using traditional teaching methods. Virtual laboratories are an alternative, cost-effective approach to providing students with sufficient preparatory information. Research on the use of virtual labs in allied health education is limited. The current study investigated the benefits, challenges, and perceived impact of a virtual lab in an allied health program. The sample consisted of 64 students (55 females, 9 males) enrolled in a university medical laboratory science program. A convergent mixed-methods approach (Likert survey, open-ended questions, think-aloud protocol data) revealed that students had positive attitudes towards visual learning, authenticity, learner control, organization, and scaffolding afforded by the virtual lab. Challenges reported included navigational difficulties, an absence of control over content selection, and lack of understanding for certain concepts. Over 90% of students agreed that the virtual lab helped them prepare for hands-on laboratory sessions and that they would use this format of instruction again. Overall, 84% of the students agreed that the virtual lab helped them to achieve greater success in learning.

A Macintosh-Based Scientific Images Video Analysis System

NASA Technical Reports Server (NTRS)

Groleau, Nicolas; Friedland, Peter (Technical Monitor)

1994-01-01

A set of experiments was designed at MIT's Man-Vehicle Laboratory in order to evaluate the effects of zero gravity on the human orientation system. During many of these experiments, the movements of the eyes are recorded on high quality video cassettes. The images must be analyzed off-line to calculate the position of the eyes at every moment in time. To this aim, I have implemented a simple inexpensive computerized system which measures the angle of rotation of the eye from digitized video images. The system is implemented on a desktop Macintosh computer, processes one play-back frame per second and exhibits adequate levels of accuracy and precision. The system uses LabVIEW, a digital output board, and a video input board to control a VCR, digitize video images, analyze them, and provide a user friendly interface for the various phases of the process. The system uses the Concept Vi LabVIEW library (Graftek's Image, Meudon la Foret, France) for image grabbing and displaying as well as translation to and from LabVIEW arrays. Graftek's software layer drives an Image Grabber board from Neotech (Eastleigh, United Kingdom). A Colour Adapter box from Neotech provides adequate video signal synchronization. The system also requires a LabVIEW driven digital output board (MacADIOS II from GW Instruments, Cambridge, MA) controlling a slightly modified VCR remote control used mainly to advance the video tape frame by frame.

Are Africans, Europeans, and Asians Different “Races”? A Guided-Inquiry Lab for Introducing Undergraduate Students to Genetic Diversity and Preparing Them to Study Natural Selection

PubMed Central

Kalinowski, Steven T.; Andrews, Tessa M.; Leonard, Mary J.; Snodgrass, Meagan

2012-01-01

Many students do not recognize that individual organisms within populations vary, and this may make it difficult for them to recognize the essential role variation plays in natural selection. Also, many students have weak scientific reasoning skills, and this makes it difficult for them to recognize misconceptions they might have. This paper describes a 2-h laboratory for college students that introduces them to genetic diversity and gives them practice using hypothetico-deductive reasoning. In brief, the lab presents students with DNA sequences from Africans, Europeans, and Asians, and asks students to determine whether people from each continent qualify as distinct “races.” Comparison of the DNA sequences shows that people on each continent are not more similar to one another than to people on other continents, and therefore do not qualify as distinct races. Ninety-four percent of our students reported that the laboratory was interesting, and 79% reported that it was a valuable learning experience. We developed and used a survey to measure the extent to which students recognized variation and its significance within populations and showed that the lab increased student awareness of variation. We also showed that the lab improved the ability of students to construct hypothetico-deductive arguments. PMID:22665587

Revitalization of clinical skills training at the University of the Western Cape.

PubMed

Jeggels, J D; Traut, A; Kwast, M

2010-06-01

Most educational institutions that offer health related qualifications make use of clinical skills laboratories. These spaces are generally used for the demonstration and assessment of clinical skills. The purpose of this paper is to share our experiences related to the revitalization of skills training by introducing the skills lab method at the School of Nursing (SoN), University of the Western Cape (UWC). To accommodate the contextual changes as a result of the restructuring of the higher education landscape in 2003, the clinical skills training programme at UWC had to be reviewed. With a dramatic increase in the student numbers and a reduction in hospital beds, the skills lab method provided students with an opportunity to develop clinical skills prior to their placement in real service settings. The design phase centred on adopting a skills training methodology that articulates with the case-based approach used by the SoN. Kolb's, experiential learning cycle provided the theoretical underpinning for the methodology. The planning phase was spent on the development of resources. Eight staff members were trained by our international higher education collaborators who also facilitated the training of clinical supervisors and simulated patients. The physical space had to be redesigned to accommodate audio visual and information technology to support the phases of the skills lab method. The implementation of the skills lab method was phased in from the first-year level. An interactive seminar held after the first year of implementation provided feedback from all the role players and was mostly positive. The results of introducing the skills lab method include: a move by students towards self-directed clinical skills development, clinical supervisors adopting the role of facilitators of learning and experiential clinical learning being based on, amongst others, the students' engagement with simulated patients. Finally, the recommendations relate to tailor-making clinical skills training by using various aspects of teaching and learning principles, i.e. case-based teaching, experiential learning and the skills lab method.

The effects of computer-simulated experiments on high school biology students' problem-solving skills and achievement

NASA Astrophysics Data System (ADS)

Carmack, Gay Lynn Dickinson

2000-10-01

This two-part quasi-experimental repeated measures study examined whether computer simulated experiments have an effect on the problem solving skills of high school biology students in a school-within-a-school magnet program. Specifically, the study identified episodes in a simulation sequence where problem solving skills improved. In the Fall academic semester, experimental group students (n = 30) were exposed to two simulations: CaseIt! and EVOLVE!. Control group students participated in an internet research project and a paper Hardy-Weinberg activity. In the Spring academic semester, experimental group students were exposed to three simulations: Genetics Construction Kit, CaseIt! and EVOLVE! . Spring control group students participated in a Drosophila lab, an internet research project, and Advanced Placement lab 8. Results indicate that the Fall and Spring experimental groups experienced significant gains in scientific problem solving after the second simulation in the sequence. These gains were independent of the simulation sequence or the amount of time spent on the simulations. These gains were significantly greater than control group scores in the Fall. The Spring control group significantly outscored all other study groups on both pretest measures. Even so, the Spring experimental group problem solving performance caught up to the Spring control group performance after the third simulation. There were no significant differences between control and experimental groups on content achievement. Results indicate that CSE is as effective as traditional laboratories in promoting scientific problem solving and that CSE is a useful tool for improving students' scientific problem solving skills. Moreover, retention of problem solving skills is enhanced by utilizing more than one simulation.

Simulated and Virtual Science Laboratory Experiments: Improving Critical Thinking and Higher-Order Learning Skills

NASA Astrophysics Data System (ADS)

Simon, Nicole A.

Virtual laboratory experiments using interactive computer simulations are not being employed as viable alternatives to laboratory science curriculum at extensive enough rates within higher education. Rote traditional lab experiments are currently the norm and are not addressing inquiry, Critical Thinking, and cognition throughout the laboratory experience, linking with educational technologies (Pyatt & Sims, 2007; 2011; Trundle & Bell, 2010). A causal-comparative quantitative study was conducted with 150 learners enrolled at a two-year community college, to determine the effects of simulation laboratory experiments on Higher-Order Learning, Critical Thinking Skills, and Cognitive Load. The treatment population used simulated experiments, while the non-treatment sections performed traditional expository experiments. A comparison was made using the Revised Two-Factor Study Process survey, Motivated Strategies for Learning Questionnaire, and the Scientific Attitude Inventory survey, using a Repeated Measures ANOVA test for treatment or non-treatment. A main effect of simulated laboratory experiments was found for both Higher-Order Learning, [F (1, 148) = 30.32,p = 0.00, eta2 = 0.12] and Critical Thinking Skills, [F (1, 148) = 14.64,p = 0.00, eta 2 = 0.17] such that simulations showed greater increases than traditional experiments. Post-lab treatment group self-reports indicated increased marginal means (+4.86) in Higher-Order Learning and Critical Thinking Skills, compared to the non-treatment group (+4.71). Simulations also improved the scientific skills and mastery of basic scientific subject matter. It is recommended that additional research recognize that learners' Critical Thinking Skills change due to different instructional methodologies that occur throughout a semester.

Establishment of a new in vitro test method for evaluation of eye irritancy using a reconstructed human corneal epithelial model, LabCyte CORNEA-MODEL.

PubMed

Katoh, Masakazu; Hamajima, Fumiyasu; Ogasawara, Takahiro; Hata, Ken-ichiro

2013-12-01

Finding in vitro eye irritation testing alternatives to animal testing such as the Draize eye test, which uses rabbits, is essential from the standpoint of animal welfare. It has been developed a reconstructed human corneal epithelial model, the LabCyte CORNEA-MODEL, which has a representative corneal epithelium-like structure. Protocol optimization (pre-validation study) was examined in order to establish a new alternative method for eye irritancy evaluation with this model. From the results of the optimization experiments, the application periods for chemicals were set at 1min for liquid chemicals or 24h for solid chemicals, and the post-exposure incubation periods were set at 24h for liquids or zero for solids. If the viability was less than 50%, the chemical was judged to be an eye irritant. Sixty-one chemicals were applied in the optimized protocol using the LabCyte CORNEA-MODEL and these results were evaluated in correlation with in vivo results. The predictions of the optimized LabCyte CORNEA-MODEL eye irritation test methods were highly correlated with in vivo eye irritation (sensitivity 100%, specificity 80.0%, and accuracy 91.8%). These results suggest that the LabCyte CORNEA-MODEL eye irritation test could be useful as an alternative method to the Draize eye test. Copyright © 2013 Elsevier Ltd. All rights reserved.

Dr. Jason Dworkin, Project Scientist

NASA Image and Video Library

2017-12-08

Dr. Jason Dworkin, Project Scientist for NASA's OSIRIS-Rex mission is seen hear sealing a glass test tube with a sample of Allende meteorite dust which is 4.567 BILLION years old. Jason is the Chief of NASA Goddard's Astrochemistry Lab. Read more about the mission here: www.nasa.gov/mission_pages/osiris-rex Credit: NASA/Goddard/Debbie Mccallum NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Think Scientifically: Hiding Science in a Storybook

NASA Astrophysics Data System (ADS)

Van Norden, W. M.; Wawro, M.

2013-12-01

The pressure to focus on math and reading at the elementary level has increased in recent years. As a result, science education has taken a back seat in elementary classrooms. The Think Scientifically book series provides a way for science to easily integrate with existing math and reading curriculum. This story-based science literature program integrates a classic storybook format with solid solar science, to make an educational product that meets state literacy standards. Each story is accompanied by hands-on labs and activities that teachers can easily conduct in their classrooms with minimal training and materials, as well as math and language arts extensions and assessment questions. These books are being distributed through teacher workshops and conferences.

Laboratory for Atmospheres: Philosophy, Organization, Major Activities, and 1999 Highlights

NASA Technical Reports Server (NTRS)

Einaudi, Franco (Technical Monitor)

2000-01-01

The Laboratory for Atmospheres is helping to answer questions related to climate, and climate change and other scientific questions about our planet and its neighbors. The Laboratory conducts a broad theoretical and experimental research program studying all aspects of the atmospheres of the Earth and other planets, including their structural, dynamical, radiative, and chemical properties. In this report,there is a statement of the labs philosophy and a description of it's role in NASA's mission. A broad description of the research and a summary of the scientists' major accomplishments in 1999 is also included. The report also presents useful information on human resources, scientific interactions, and outreach activities with the outside community.

Prototyping a 10 Gigabit-Ethernet Event-Builder for the CTA Camera Server

NASA Astrophysics Data System (ADS)

Hoffmann, Dirk; Houles, Julien

2012-12-01

While the Cherenkov Telescope Array will end its Preperatory Phase in 2012 or 2013 with the publication of a Technical Design Report, our lab has undertaken within the french CTA community the design and prototyping of a Camera-Server, which is a PC architecture based computer, used as a switchboard assigned to each of a hundred telescopes to handle a maximum amount of scientific data recorded by each telescope. Our work aims for a data acquisition hardware and software system for the scientific raw data at optimal speed. We have evaluated the maximum performance that can be obtained by choosing standard (COTS) hardware and software (Linux) in conjunction with a 10 Gb/s switch.

Purposeful and Targeted Use of Scientists to Support In-Service Teachers' Understandings and Teaching of Scientific Inquiry and Nature of Science

ERIC Educational Resources Information Center

White, Kevin

2010-01-01

Efforts have been made to enhance teachers' understanding and teaching of NOS and/or SI by immersing teachers into the field and lab work of scientists through intensive summer institutes. Results have been mixed and the samples have been small. This may be due to several factors: implicit strategies to learn and teach about NOS and/or SI…

Special-Study Modules in a Problem-Based Learning Medical Curriculum: An Innovative Laboratory Research Practice Supporting Introduction to Research Methodology in the Undergraduate Curriculum

ERIC Educational Resources Information Center

Guner, Gul Akdogan; Cavdar, Zahide; Yener, Nilgun; Kume, Tuncay; Egrilmez, Mehtap Yuksel; Resmi, Halil

2011-01-01

We describe the organization of wet-lab special-study modules (SSMs) in the Central Research Laboratory of Dokuz Eylul Medical School, Izmir, Turkey with the aim of discussing the scientific, laboratory, and pedagogical aspects of this educational activity. A general introduction to the planning and functioning of these SSMs is given, along with…

FameLab provides competition and coaching on science communication

NASA Astrophysics Data System (ADS)

Scalice, Daniella; Weiss, Peter

2012-10-01

In today's media-intensive environment, the ability to convey science can reshape the face of scientific exploration and discovery. Many early-career scientists could benefit from training on how to communicate their work effectively to all stakeholders along their career paths, from deans and political representatives to neighbors and students, and perhaps even to public audiences through the lens of a camera or the voice of a blog.

Contention Bounds for Combinations of Computation Graphs and Network Topologies

DTIC Science & Technology

2014-08-08

member of STARnet, a Semiconductor Research Corporation program sponsored by MARCO and DARPA, and ASPIRE Lab industrial sponsors and affiliates Intel...Google, Nokia, NVIDIA , Oracle, MathWorks and Samsung. Also funded by U.S. DOE Office of Science, Office of Advanced Scientific Computing Research...DARPA Award Number HR0011-12-2- 0016, the Center for Future Architecture Research, a mem- ber of STARnet, a Semiconductor Research Corporation

Are Africans, Europeans, and Asians Different "Races"? A Guided-Inquiry Lab for Introducing Undergraduate Students to Genetic Diversity and Preparing Them to Study Natural Selection

ERIC Educational Resources Information Center

Kalinowski, Steven T.; Andrews, Tessa M.; Leonard, Mary J.; Snodgrass, Meagan

2012-01-01

Many students do not recognize that individual organisms within populations vary, and this may make it difficult for them to recognize the essential role variation plays in natural selection. Also, many students have weak scientific reasoning skills, and this makes it difficult for them to recognize misconceptions they might have. This paper…

Cyclotron Road at Berkeley Lab – U.S. Department of Energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhl, Kendra; Weitekamp, Raymond; Lehmann, Marcus

The Department of Energy is testing a new model for clean energy research and development (R&D) through a program called Cyclotron Road. The goal is to support scientific R&D that is still too risky for private‐sector investment, and too applied for academia. Participants receive the time, space and capital to pursue their research and the support to find viable pathways to the market.

Targeting N-RAS as a Therapeutic Approach for Melanoma

DTIC Science & Technology

2013-10-01

Labs (Woburn, MA), Sigma-Aldrich (St. Louis, MO) and Fisher Scientific (Pittsburgh, PA), respectively. Z-VAD-FMK was purchased from R&D Systems ...proliferation assays (MTS assay) and caspase assays were performed with CellTiter 96 AQueous Non-Radioactive Cell Proliferation Assay kit and Caspase-Glo 3...7 Assay Systems (Promega [Madison, WI]) according to the manufacturers’ protocols. Briefly, for the assays employing inhibitors, cells were plated

FUTURO REMOTO 2015: researchers meet people.

NASA Astrophysics Data System (ADS)

De Lucia, Maddalena; Fedele, Alessandro; Esposito, Roberta; Torello, Vincenzo; Nave, Rosella; Pino, Nicola Alessandro; Russo, Massimo; Alessio, Giuliana; Gaudiosi, Germana; Nappi, Rosa; Belviso, Pasquale; Carandente, Antonio; De Cesare, Walter; Sansivero, Fabio; Siniscalchi, Valeria; Borgstrom, Sven; Milano, Girolamo; Pasquale Ricciardi, Giovanni; De Natale, Giuseppe

2016-04-01

As participant of the 29th Edition of the cultural initiative "Futuro Remoto 2015", the INGV section of Naples Osservatorio Vesuviano has realized a temporary exhibition aimed to build bridges between the scientific community and the public. The event, a festival of art, culture, science and technology, has taken place on October 15th - 19th 2015, in Naples, Italy, in the city center, and was organized by "Città della Scienza", the science center of the city of Naples, belonging to the ECSITE netwok.. The total number of visitors was about 130.000 people. It was a free and open access event, funded by public institutions. Sharing their scientific expertise with the public, in the "Terra" ("Earth") stand the INGV-OV researchers have shown, with interactive labs, how progress in technology and research develope and allow a better understanding of the dynamic processes and of the evolution of our planet. Popularizing science, when widely accessible to the people, make the knowledge not remaining confined to an elite, being efficiently spread in society, with deep implications in the social role of researchers. Practical activities and labs, dialogues and interaction with researchers of INGV-OV have allowed young and adult public, schools, students, experts or simply curious people to deepen burning issues in an area exposed to high seismic and volcanic risk.

NBodyLab: A Testbed for Undergraduates Utilizing a Web Interface to NEMO and MD-GRAPE2 Hardware

NASA Astrophysics Data System (ADS)

Johnson, V. L.; Teuben, P. J.; Penprase, B. E.

An N-body simulation testbed called NBodyLab was developed at Pomona College as a teaching tool for undergraduates. The testbed runs under Linux and provides a web interface to selected back-end NEMO modeling and analysis tools, and several integration methods which can optionally use an MD-GRAPE2 supercomputer card in the server to accelerate calculation of particle-particle forces. The testbed provides a framework for using and experimenting with the main components of N-body simulations: data models and transformations, numerical integration of the equations of motion, analysis and visualization products, and acceleration techniques (in this case, special purpose hardware). The testbed can be used by students with no knowledge of programming or Unix, freeing such students and their instructor to spend more time on scientific experimentation. The advanced student can extend the testbed software and/or more quickly transition to the use of more advanced Unix-based toolsets such as NEMO, Starlab and model builders such as GalactICS. Cosmology students at Pomona College used the testbed to study collisions of galaxies with different speeds, masses, densities, collision angles, angular momentum, etc., attempting to simulate, for example, the Tadpole Galaxy and the Antenna Galaxies. The testbed framework is available as open-source to assist other researchers and educators. Recommendations are made for testbed enhancements.

Inquiry into chemotherapy-induced p53 activation in cancer cells as a model for teaching signal transduction.

PubMed

Srougi, Melissa C; Carson, Susan

2013-01-01

Intracellular and extracellular communication is conducted through an intricate and interwoven network of signal transduction pathways. The mechanisms for how cells speak with one another are of significant biological importance to both basic and industrial scientists from a number of different disciplines. We have therefore developed and implemented a new laboratory-intensive course that teaches students the theory and techniques used to study cell signaling pathways. Students learn these methodologies as they conduct a hypothesis-driven research project where they elucidate the mechanism of breast cancer cell death caused by a cancer chemotherapeutic agent. While each lab experiment can be conducted independently, the findings build upon one another to form the beginnings of a signaling pathway. In the lecture component of the course, students investigate different signaling pathways and the methods employed to study them. In addition, students actively participate in journal article discussions where they assess the primary scientific literature. We evaluated the course over two semesters and found that in both semesters learning outcomes were met by both undergraduate and graduate students. The evaluation of the course was based on a number of instructor assessments of student work, including lab reports, experimental results, journal article discussions, and a final cumulative exam. Furthermore, students' self-assessments revealed gains in perceived confidence in both conceptual knowledge and technical skills Copyright © 2013 Wiley-Liss, Inc.

STS-98 payload U.S. Lab Destiny is moved into Atlantis' payload bay

NASA Technical Reports Server (NTRS)

2001-01-01

KENNEDY SPACE CENTER, Fla. -- Technicians in the Payload Changeout Room work to secure the U.S. Lab Destiny in the orbiter'''s payload bay. The PCR is the enclosed, environmentally controlled portion of the rotating service structure that supports payload delivery at the launch pad and vertical installation in the orbiter payload bay. Destiny, a key element in the construction of the International Space Station, is 28 feet long and weighs 16 tons. This research and command-and- control center is the most sophisticated and versatile space laboratory ever built. It will ultimately house a total of 23 experiment racks for crew support and scientific research. STS-98 is the seventh construction flight to the ISS. Launch of STS-98 is scheduled for Jan. 19 at 2:11 a.m. EST.

My Lifelong Passion for Biochemistry and Anaerobic Microorganisms.

PubMed

Thauer, Rudolf Kurt

2015-01-01

Early parental influence led me first to medical school, but after developing a passion for biochemistry and sensing the need for a deeper foundation, I changed to chemistry. During breaks between semesters, I worked in various biochemistry labs to acquire a feeling for the different areas of investigation. The scientific puzzle that fascinated me most was the metabolism of the anaerobic bacterium Clostridium kluyveri, which I took on in 1965 in Karl Decker's lab in Freiburg, Germany. I quickly realized that little was known about the biochemistry of strict anaerobes such as clostridia, methanogens, acetogens, and sulfate-reducing bacteria and that these were ideal model organisms to study fundamental questions of energy conservation, CO2 fixation, and the evolution of metabolic pathways. My passion for anaerobes was born then and is unabated even after 50 years of study.

U.S. Rep. Dave Weldon looks at the U.S. Lab Destiny in the SSPF.

NASA Technical Reports Server (NTRS)

1999-01-01

In the Space Station Processing Facility, Thomas R. 'Randy' Galloway, with the Space Station Hardware Integration Office, points out a feature to U.S. Rep. Dave Weldon (right) in the U.S. Lab, called 'Destiny.' In the far background is Dana Gartzke, the congressman's chief of staff. Weldon is on the House Science Committee and vice chairman of the Space and Aeronautics Subcommittee. Destiny is scheduled to be launched on Space Shuttle Endeavour in early 2000. It will become the centerpiece of scientific research on the ISS, with five equipment racks aboard to provide essential functions for station systems, including high data-rate communications, and to maintain the station's orientation using control gyroscopes launched earlier. Additional equipment and research racks will be installed in the laboratory on subsequent Shuttle flights.

Service-Learning in the Undergraduate Geoscience Classroom: Establishing Community Partnerships to Enhance Education in Climate Change Science in Local Schools

NASA Astrophysics Data System (ADS)

Joseph, L. H.; Faust, R.

2009-12-01

The complexity of the science surrounding global climate change makes effective communication about this issue to the public difficult, especially at a time when many would argue that public understanding of science in general has decreased. As a service-learning project, a partnership was created between an upper-level environmental studies climate change class at Ursinus College (UC) and the UC Science In Motion (SIM) program to construct an appropriate lab activity that would foster scientific knowledge and abilities in high school students particularly in relation to basic climate change science. The Pennsylvania SIM program is a state-funded initiative to make a selection of lab activities, equipment, and expertise available to teachers at secondary schools at no cost to the schools with the goal to “strengthen the quality of science education for all.” The twelve SIM sites are dispersed throughout PA and serve over 200 school districts overall. The UC SIM program has served over 30 local schools with labs and activities from which the teachers may select. Prior to the partnership discussed here, there were no labs in the UC SIM program that incorporated the concepts of climate change and though a “drop-off” climate change lab was desired, the staff would have no time to design one. The adaptation of a previously written lab set on climate change was assigned as a project for the 9 environmental studies majors at UC enrolled in a Fall 2008 course exploring the science of global climate change. While an advanced course within the environmental studies curriculum, the science backgrounds of the college students themselves were mixed, ranging from science majors to students for whom this was the first or second science course taken at college. In addition to the typical load of coursework, the students worked in small groups on this project throughout the semester, collecting the supplies, testing and adapting the labs, creating a video to guide users through the lab, visiting a local high school for a trial run, and editing and writing the worksheets and teacher guides. It was necessary for the students to clearly understand the concepts behind the labs so the activities could be adapted and presented appropriately. Effective communication of the concepts through visuals and written work was also important. Continued coordination with UC SIM staff was required and helpful and the final product was turned over to the UC SIM for further adaptation and use. The college students appreciated the positive impact the lab could have on climate change science education even after the end of the semester and found it both motivating and rewarding. Partnering with an organization already established and utilized as a source of science education activities for the local school districts ensured quick dissemination of the lab activity. Between 1/09-6/09, ~12 teachers have used this global climate change lab with ~500 students of mixed academic levels. The lab has received positive feedback from teachers and supplies have been duplicated to meet demand, likely indicative of a desire for accessible lab activities within the field of environmental science.

Catchments network on badlands around Mediterranean area (RESOBAM)

NASA Astrophysics Data System (ADS)

Copard, Yoann; Lebouteiller, Caroline; Regues-Munoz, David; Latron, Jerome; Solé-Benet, Albert; Canton, Yolanda; Nadal-Romero, Estela; Della Seta, Marta; Rossi, Mauro; Capolongo, Domenico; Maquaire, Olivier; Forey, Estelle; Di-Giovanni, Christian; Gallart, Francesc; Delmonte, Maurizio; Vergari, Francesca; Massei, Nicolas; Torri, Dino

2016-04-01

Between 2013 and 2014, a network funded by MISTRALS-ENVIMED institution, was born around some instrumented catchments developing a badland-type morphology. This network has grouped 3 countries (France, Spain and Italy) with 12 scientific labs. RESOBAM has concerned two sites in France (Draix-Bléone and Vaches Noires), three in Spain (Vallcebre, Araguas and El Cautivo) and some sites in Italy (Tuscany, Basilicata). Main goal of this network was to federate the research around badlands at the European scale, by proposing some scientific topics as: sediment and water transports / budget, (bio)geochemical cycles, agricultural (farming), education, restoration, cultural heritage, soil conservation / biodiversity, climatic change etc. Other main interests were also to propose some common scientific projects and the development of students exchanges. This communication presents the synthesis of our four meetings held at Draix, Zaragoza, Almeriá and Rouen and some perspectives to continue this network.

Best Practices: How to Evaluate Psychological Science for Use by Organizations.

PubMed

Fiske, Susan T; Borgida, Eugene

2011-01-01

We discuss how organizations can evaluate psychological science for its potential usefulness to their own purposes. Common sense is often the default but inadequate alternative, and bench-marking supplies only collective hunches instead of validated principles. External validity is an empirical process of identifying moderator variables, not a simple yes-no judgment about whether lab results replicate in the field. Hence, convincing criteria must specify what constitutes high-quality empirical evidence for organizational use. First, we illustrate some theories and science that have potential use. Then we describe generally accepted criteria for scientific quality and consensus, starting with peer review for quality, and scientific agreement in forms ranging from surveys of experts to meta-analyses to National Research Council consensus reports. Linkages of basic science to organizations entail communicating expert scientific consensus, motivating managerial interest, and translating broad principles to specific contexts. We close with parting advice to both sides of the researcher-practitioner divide.

The EGS Data Collaboration Platform: Enabling Scientific Discovery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weers, Jonathan D; Johnston, Henry; Huggins, Jay V

Collaboration in the digital age has been stifled in recent years. Reasonable responses to legitimate security concerns have created a virtual landscape of silos and fortified castles incapable of sharing information efficiently. This trend is unfortunately opposed to the geothermal scientific community's migration toward larger, more collaborative projects. To facilitate efficient sharing of information between team members from multiple national labs, universities, and private organizations, the 'EGS Collab' team has developed a universally accessible, secure data collaboration platform and has fully integrated it with the U.S. Department of Energy's (DOE) Geothermal Data Repository (GDR) and the National Geothermal Data Systemmore » (NGDS). This paper will explore some of the challenges of collaboration in the modern digital age, highlight strategies for active data management, and discuss the integration of the EGS Collab data management platform with the GDR to enable scientific discovery through the timely dissemination of information.« less

Emotional and deliberative reactions to a public crisis: Mad Cow disease in France.

PubMed

Sinaceur, Marwan; Heath, Chip; Cole, Steve

2005-03-01

Although most theories of choice are cognitive, recent research has emphasized the role of emotions. We used a novel context--the Mad Cow crisis in France--to investigate how emotions alter choice even when consequences are held constant. A field study showed that individuals reduced beef consumption in months after many newspaper articles featured the emotional label "Mad Cow," but beef consumption was unaffected after articles featured scientific labels for the same disease. The reverse pattern held for the disease-related actions of a government bureaucracy. A lab study showed that the Mad Cow label induces people to make choices based solely on emotional reactions, whereas scientific labels induce people to consider their own probability judgments. Although the Mad Cow label produces less rational behavior than scientific labels, it is two to four times more common in the environment.

Enhancing Communication Skills of Pre-service Physics Teacher through HOT Lab Related to Electric Circuit

NASA Astrophysics Data System (ADS)

Malik, A.; Setiawan, A.; Suhandi, A.; Permanasari, A.; Dirgantara, Y.; Yuniarti, H.; Sapriadil, S.; Hermita, N.

2018-01-01

This study aimed to investigate the improvement to pre-service teacher’s communication skills through Higher Order Thinking Laboratory (HOT Lab) on electric circuit topic. This research used the quasi-experiment method with pretest-posttest control group design. Research subjects were 60 students of Physics Education in UIN Sunan Gunung Djati Bandung. The sample was chosen by random sampling technique. Students’ communication skill data collected using a communication skills test instruments-essays form and observations sheets. The results showed that pre-service teacher communication skills using HOT Lab were higher than verification lab. Student’s communication skills in groups using HOT Lab were not influenced by gender. Communication skills could increase due to HOT Lab based on problems solving that can develop communication through hands-on activities. Therefore, the conclusion of this research shows the application of HOT Lab is more effective than the verification lab to improve communication skills of pre-service teachers in electric circuit topic and gender is not related to a person’s communication skills.