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Sample records for secondary standard radionuclide

  1. Sources of secondary radionuclide releases from Hanford Operations

    SciTech Connect

    Heeb, C.M.; Gydesen, S.P.

    1994-05-01

    This report considers Hanford facilities and operations with the potential to be secondary radionuclide release sources. Facilities that produced radionuclides or processed products of fission reactions and were not covered in previous source term reports are included in this report. The following facilities are described and any potentially significant releases from them are estimated: PUREX (1956--1972, 1983--1988) and REDOX (1952--1967)--campaigns with non-standard feed material (materials other than fuel from single-pass reactors); C PLANT (Hot Semi-Works)--pilot plant and strontium recovery; Z Plant--plutonium finishing; U and UO{sub 3} Plants--uranium recovery; 108 B Plant--tritium extraction; 300 Area Plutonium Recycle Test Reactor (PRTR); 300 Area Low Power Test Reactors; Criticality Accidents; and 400 Area Fast Flux Test Facility (FFTF). The method of analysis was to examine each facility, give a brief description of its purpose and operations, and describe the types of material the facility processed as an indication of the radionuclides it had the potential to release. Where possible, specific radionuclides are estimated and values from the original documents are reported.

  2. 1999 INEEL National Emission Standards for Hazardous Air Pollutants - Radionuclides

    SciTech Connect

    J. W. Tkachyk

    2000-06-01

    Under Section 61.94 of Title 40, Code of Federal Regulations (CFR), Part 61, Subpart H, ''National Emission Standards for Emission of Radionuclides Other Than Radon From Department of Energy Facilities,'' each Department of Energy (DOE) facility must submit an annual report documenting compliance. This report addresses the Section 61.94 reporting requirements for operations at the Idaho National Engineering and Environmental Laboratory (INEEL) for calendar year (CY) 1999. The Idaho Operations Office of the DOE is the primary contract concerning compliance with the National Emission Standards for Hazardous Air Pollutants (NESHAPs) at the INEEL. For CY 1999, airborne radionuclide emissions from the INEEL operations were calculated to result in a maximum individual dose to a member of the public of 7.92E-03 mrem (7.92E-08 Sievert). This effective dose equivalent (EDE) is well below the 40 CFR 61, Subpart H, regulatory standard of 10 mrem per year (1.0E-04 Sievert per year).

  3. 1998 INEEL National Emission Standard for Hazardous Air Pollutants - Radionuclides

    SciTech Connect

    J. W. Tkachyk

    1999-06-01

    Under Section 61.94 of Title 40, Code of Federal Regulations (CFR), Part 61, Subpart H, ''National Emission Standards for Emission of Radionuclides Other Than Radon From Department of Energy Facilities,'' each Department of Energy (DOE) facility must submit an annual report documenting compliance. This report addresses the Section 61.94 reporting requirements for operations at the Idaho National Engineering and Environmental Laboratory (INEEL) for calendar year (CY) 1998. The Idaho Operations Office of the DOE is the primary contract concerning compliance with the National Emission Standards for Hazardous Air Pollutants (NESHAPs) at the INEEL. For CY 1998, airborne radionuclide emissions from the INEEL operations were calculated to result in a maximum individual dose to a member of the public of 7.92E-03 mrem (7.92E-08 Sievert). This effective dose equivalent (EDE) is well below the 40 CFR 61, Subpart H, regulatory standard of 10 mrem per year (1.0E-04 Sievert per year).

  4. Radionuclide Incorporation in Secondary Crystalline Minerals from Chemical Weathering of Waste Glasses

    SciTech Connect

    Mattigod, Shas V.; Serne, R JEFFREY.; McGrail, B PETER.; Legore, Virginia L.

    2002-09-01

    Data from corrosion and radionuclide sequestration studies on two waste glasses indicated chemical weathering resulted in the formation of zeolite minerals such as herschelite and analcime. We also found that these minerals incorporated {approx}8 - 22%, {approx}1- 13% and {approx}8 - 25% of spiked 125-I, 99-Tc, and 75-Se respectively. Increasing concentrations of radionuclides in spike solution resulted in higher degree of sequestration as observed by significantly higher proportion of stable isotopes ({approx}70 - 95% I, {approx}58 - 100% Re, and {approx}100% Se) in secondary minerals. The radionuclide incorporation mechanisms for these minerals appear to be mainly isomorphic substitution of Se and Re in tetrahedral sites and iodide substitution for framework oxygen.

  5. Secondary Uranium-Phase Paragenesis and Incorporation of Radionuclides into Secondary Phase

    SciTech Connect

    R. Finch

    2001-06-05

    The purpose of this analysis/model report (AMR) is to assess the potential for uranium (U) (VI) compounds, formed during the oxidative corrosion of spent uranium-oxide (UO{sub 2}) fuels, to sequester certain radionuclides and, thereby, limit their release. The ''unsaturated drip tests'' being conducted at Argonne National Laboratory (ANL) provide the basis of this AMR (Table 1). The ANL drip tests on spent fuel are the only experiments on fuel corrosion from which solids have been analyzed for trace levels of radionuclides. Brief summaries are provided of the results from other selected corrosion and dissolution experiments on spent UO{sub 2} fuels, specifically those conducted under nominally oxidizing conditions. Discussions of the current understanding of thermodynamic and kinetic properties of U(VI) compounds is provided in order to outline the scientific basis for modeling precipitation and dissolution of potential radionuclide-bearing phases under repository-relevant conditions. Attachment I provides additional information on corrosion mechanisms and behaviors of radionuclides in the tests at ANL. Attachment II reviews occurrence, formation, and alteration (collectively known as paragenesis) of naturally occurring U(VI) minerals because natural mineral occurrences can be used to assess the possible long-term behaviors of U(VI) compounds formed in short-term laboratory experiments and to extrapolate experimental results to repository-relevant time scales. This AMR develops a model for calculating dissolved concentrations of radionuclides that are incorporated into U(VI) compounds, which is an alternative to models currently used in TSPA to calculate dissolved concentration limits for certain radionuclides. In particular, the model developed in this AMR applies to Np (neptunium) concentrations being controlled by solid uranyl oxyhydroxides that are known to contain trace levels of Np. The results of this AMR and the conceptual model developed from it and

  6. National Emission Standards for Hazardous Air Pollutants—Calendar Year 2010 INL Report for Radionuclides (2011)

    SciTech Connect

    Mark Verdoorn; Tom Haney

    2011-06-01

    This report documents the calendar Year 2010 radionuclide air emissions and resulting effective dose equivalent to the maximally exposed individual member of the public from operations at the Department of Energy's Idaho National Laboratory Site. This report was prepared in accordance with the Code of Federal Regulations, Title 40, 'Protection of the Environment,' Part 61, 'National Emission Standards for Hazardous Air Pollutants,' Subpart H, 'National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.'

  7. Radionuclide Retention Mechanisms in Secondary Waste-Form Testing: Phase II

    SciTech Connect

    Um, Wooyong; Valenta, Michelle M.; Chung, Chul-Woo; Yang, Jungseok; Engelhard, Mark H.; Serne, R. Jeffrey; Parker, Kent E.; Wang, Guohui; Cantrell, Kirk J.; Westsik, Joseph H.

    2011-09-26

    This report describes the results from laboratory tests performed at Pacific Northwest National Laboratory (PNNL) for Washington River Protection Solutions (WRPS) to evaluate candidate stabilization technologies that have the potential to successfully treat liquid secondary waste stream effluents produced by the Hanford Tank Waste Treatment and Immobilization Plant (WTP). WRPS is considering the design and construction of a Solidification Treatment Unit (STU) for the Effluent Treatment Facility (ETF) at Hanford. The ETF, a multi-waste, treatment-and-storage unit that has been permitted under the Resource Conservation and Recovery Act (RCRA), can accept dangerous, low-level, and mixed wastewaters for treatment. The STU needs to be operational by 2018 to receive secondary liquid waste generated during operation of the WTP. The STU will provide the additional capacity needed for ETF to process the increased volume of secondary waste expected to be produced by WTP. This report on radionuclide retention mechanisms describes the testing and characterization results that improve understanding of radionuclide retention mechanisms, especially for pertechnetate, {sup 99}TcO{sub 4}{sup -} in four different waste forms: Cast Stone, DuraLith alkali aluminosilicate geopolymer, encapsulated fluidized bed steam reforming (FBSR) product, and Ceramicrete phosphate bonded ceramic. These data and results will be used to fill existing data gaps on the candidate technologies to support a decision-making process that will identify a subset of the candidate waste forms that are most promising and should undergo further performance testing.

  8. National Emission Standards for Hazardous Air Pollutants—Calendar Year 2011 INL Report for Radionuclides (2012)

    SciTech Connect

    Mark Verdoorn; Tom Haney

    2012-06-01

    This report documents the calendar year 2011 radionuclide air emissions and resulting effective dose equivalent to the maximally exposed individual member of the public from operations at the Department of Energy's Idaho National Laboratory Site. This report was prepared in accordance with the Code of Federal Regulations, Title 40, 'Protection of the Environment,' Part 61, 'National Emission Standards for Hazardous Air Pollutants,' Subpart H, 'National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.' The effective dose equivalent to the maximally exposed individual member of the public was 4.58E-02 mrem per year, 0.46 percent of the 10 mrem standard.

  9. National Emission Standards for Hazardous Air Pollutants. Calendar Year 2012 INL Report for Radionuclides (2013)

    SciTech Connect

    Verdoorn, Mark; Haney, Tom

    2013-06-01

    This report documents the calendar year 2011 radionuclide air emissions and resulting effective dose equivalent to the maximally exposed individual member of the public from operations at the Department of Energy’s Idaho National Laboratory Site. This report was prepared in accordance with the Code of Federal Regulations, Title 40, ''Protection of the Environment,'' Part 61, ''National Emission Standards for Hazardous Air Pollutants,'' Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.'' The effective dose equivalent to the maximally exposed individual member of the public was 4.58E-02 mrem per year, 0.46 percent of the 10 mrem standard.

  10. National Emission Standards for Hazardous Air Pollutants. Calendar Year 2013 INL Report for Radionuclides [2014

    SciTech Connect

    Verdoorn, Mark; Haney, Tom

    2014-06-01

    This report documents the calendar year 2013 radionuclide air emissions and resulting effective dose equivalent to the maximally exposed individual member of the public from operations at the Department of Energy’s Idaho National Laboratory Site. This report was prepared in accordance with the Code of Federal Regulations, Title 40, ''Protection of the Environment,'' Part 61, ''National Emission Standards for Hazardous Air Pollutants,'' Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.'' The effective dose equivalent to the maximally exposed individual member of the public was 3.02 E-02 mrem per year, 0.30 percent of the 10 mrem standard.

  11. Radionuclide Incorporation in Secondary Crystalline Minerals Resulting from Chemical Weathering of Selected Waste Glasses: Progress Report for Subtask 3d

    SciTech Connect

    SV Mattigod; DI Kaplan; VL LeGore; RD Orr; HT Schaef; JS Young

    1998-10-23

    Experiments were conducted in fiscal year 1998 by Pacific Northwest National Laboratory to evaluate potential incorporation of radionuclides in secondary mineral phases that form from weathering vitrified nuclear waste glasses. These experiments were conducted as part of the Immobilized Low- Activity Waste-Petiormance Assessment (ILAW-PA) to generate data on radionuclide mobilization and transport in a near-field enviromnent of disposed vitrified wastes. An initial experiment was conducted to identify the types of secondary minerals that form from two glass samples of differing compositions, LD6 and SRL202. Chemical weathering of LD6 glass at 90oC in contact with an aliquot of uncontaminated Hanford Site groundwater resulted in the formation of a Crystalline zeolitic mineral, phillipsite. In contrast similar chemical weathering of SRL202 glass at 90"C resulted in the formation of a microcrystalline smectitic mineral, nontronite. A second experiment was conducted at 90"C to assess the degree to which key radionuclides would be sequestered in the structure of secondary crystalline minerals; namely, phillipsite and nontronite. Chemical weathering of LD6 in contact with radionuclide-spiked Hanford Site groundwater indicated that substantial ilactions of the total activities were retained in the phillipsite structure. Similar chemical weathering of SRL202 at 90"C, also in contact with radionuclide-spiked Hanford Site groundwater, showed that significant fractions of the total activities were retained in the nontronite structure. These results have important implications regarding the radionuclide mobilization aspects of the ILAW-PA. Additional studies are required to confkm the results and to develop an improved under- standing of mechanisms of sequestration and attenuated release of radionuclides to help refine certain aspects of their mobilization.

  12. Automated secondary standard for liquid flowmeters

    NASA Technical Reports Server (NTRS)

    Hobart, H. F.

    1977-01-01

    Calibration time is reduced from one hour to fifteen minutes. Accuracies of flowmeter calibrations are approximately 99.75 percent, using this standard. Standard is also used to test or set flow switches.

  13. Radionuclide Incorporation in Secondary Crystalline Minerals Resulting from Chemical Weathering of Selected Waste Glasses: Progress Report: Task kd.5b

    SciTech Connect

    Mattigod, Shas V.; Serne, R. Jeffrey; Legore, Virginia L.; Parker, Kent E.; Orr, Robert D.; McCready, David E.; Young, James S.

    2003-09-29

    Experiments were conducted by Pacific Northwest National Laboratory to evaluate potential incorporation of radionuclides in secondary mineral phases that form from weathering vitrified nuclear waste glasses. These experiments were conducted as part of the Immobilized Low-Activity Waste-Performance Assessment (ILAW-PA) to generate data on radionuclide mobilization and transport in a near-field environment of disposed vitrified wastes. The results of these experiments demonstrated that radionuclide sequestration can be significantly enhanced by promoting the formation of cage structured minerals such as sodalite from weathering glasses. These results have important implications regarding radionuclide sequestration/mobilization aspects that are not currently accounted for in the ILAW PA. Additional studies are required to confirm the results and to develop an improved understanding of the mechanisms of sequestration of radionuclides into the secondary and tertiary weathering products of the ILAW glass to help refine how contaminants are released from the near-field disposal region out into the accessible environment. Of particular interest is to determine whether the contaminants remain sequestered in the glass weathering products for hundreds to thousands of years. If the sequestration can be shown to continue for long periods, another immobilization process can be added to the PA analysis and predicted risks should be lower than past predictions.

  14. Drinking water standards for radionuclides: the dilemma and a possible resolution.

    PubMed

    Kocher, D C

    2001-05-01

    The U.S. Environmental Protection Agency (EPA) is undertaking a revision of existing standards for radionuclides in drinking water. The Safe Drinking Water Act specifies that any revision "shall maintain or provide for greater protection of the health of persons." This provision appears to require that existing standards (maximum contaminant levels, MCLs) cannot be relaxed. Such a requirement presents a dilemma for two reasons. First, EPA has shown that the MCL for radium was not cost-effective. Second, MCLs for beta/gamma-emitting radionuclides incorporate outdated approaches to estimating dose from ingestion of radionuclides and, thus, appear to violate provisions of the Safe Drinking Water Act concerning the use of sound science in setting standards. We suggest that this dilemma can be resolved based on an argument that the standard for protection of public health mandated by the Safe Drinking Water Act is one of applying best-available technology for removal of contaminants from drinking water at a reasonable cost, not one of meeting previously established MCLs. PMID:11316079

  15. Science, Levels 7-12. Secondary Core Curriculum Standards.

    ERIC Educational Resources Information Center

    Utah State Board of Education, Salt Lake City. Div. of Curriculum and Instruction.

    This document presents the core science curriculum standards which must be completed by all students as a requisite for graduation from Utah's secondary schools. Contained within are the elementary and secondary school program of studies and high school graduation requirements. Each course entry for grades 7-12 contains: course title, unit of…

  16. Extensions to the Beta Secondary Standard BSS 2

    NASA Astrophysics Data System (ADS)

    Behrens, R.; Buchholz, G.

    2011-11-01

    Since several years, the irradiation facility for beta radiation, the Beta Secondary Standard BSS 2 developed at PTB, has been in worldwide use for the performance of irradiations with calibrated beta sources. Due to recent developments in eye tumor therapy, in eye lens dosimetry, and in soft- and hardware technology, several extensions have been added to the BSS 2. These extensions are described in this paper: 1. The possibility of using a 106Ru/106Rh beta source was added as this radionuclide is often used in tumor therapy. 2. The (small) contribution due to photon radiation was included in the dose (rate) reported by the BSS 2, as this was missing in the past. 3. The quantity personal dose equivalent at a depth of 3 mm, Hp(3), was implemented due to recent findings on the radio sensitivity of the eye lens regarding cataract induction and the subsequent lowering of the dose limit from 150 mSv down to 20 mSv per year; 4. The correction for ambient conditions (air temperature, pressure, and relative humidity) was improved in order to adequately handle the quantity Hp(3) and in order to extend the range of use beyond 25°C. 5. A checksum test was added to the software to secure the calibration data against (un)intended changes. 6. The connection of the PC and the BSS 2 has been changed to a network interface (TCP/IP) in order to be able to use up-to-date computers not containing a parallel and a serial port. 7. A rod phantom was added in order to make sure the mechanical set-up is of high quality. All these extensions have been implemented in the PTB's BSS 2 model. The routine implementation of extension 1 is still under investigation by the manufacturer. The commercially available BSS 2 will contain extensions 2 to 6 starting approximately in 2012, while extension 7 has already been incorporated since 2011. Extensions 2 to 4 will also be available for old BSS 2 versions via a software update, starting approximately at the beginning of 2012. Extension 6 will be

  17. Interior Design Standards in the Secondary FCS Curriculum

    ERIC Educational Resources Information Center

    Katz, Shana H.; Smith, Bettye P.

    2006-01-01

    This article deals with a study on interior design standards in the secondary FCS curriculum. This study assessed the importance FCS teachers placed on content standards in the interior design curriculum to help determine the amount of time and emphasis to place on the units within the courses. A cover letter and questionnaire were sent…

  18. Standards of radium-226: from Marie Curie to the International Committee for Radionuclide Metrology.

    PubMed

    Coursey, B M; Collé, R; Coursey, J S

    2002-01-01

    In the early part of the 20th century, the pioneers of radioactivity research, led by Marie Curie, Ernest Rutherford and Stefan Meyer, formed a Commission internationale des étalons de radium. The Commission made arrangements for the preparation and intercomparisons of the international standards of radium, which were identified as the Paris standard and the Vienna standard. Otto Hönigschmid from Vienna prepared a first set of international secondary standards in 1912 and a second set in 1934. In both instances, these secondary standards were compared by gamma-ray measurements with the Paris and Vienna standards. The usage of these international standards of radium in the 20th century is described.

  19. Distribution of radionuclides in an iron calibration standard for a free release measurement facility.

    PubMed

    Hult, Mikael; Stroh, Heiko; Marissens, Gerd; Tzika, Faidra; Lutter, Guillaume; Šurán, Jiri; Kovar, Petr; Skala, Lukas; Sud, Jaromír

    2016-03-01

    A Europallet-sized calibration standard composed of 12 grey cast iron tubes contaminated with (60)Co and (110m)Ag with a mass of 246kg was developed. As the tubes were produced through centrifugal casting it was of particular concern to study the distribution of radionuclides in the radial direction of the tubes. This was done by removing 72 small samples (swarf) of ~0.3g each on both the inside and outside of the tubes. All of the samples were measured in the underground laboratory HADES.

  20. Radionuclide measurement proficiency testing for SNAP using NPL waste drum standards.

    PubMed

    Miller, T J

    2010-12-01

    AWE has participated in two rounds of radionuclide measurement proficiency testing using 200 l waste drum standards prepared by the National Physical Laboratory (NPL). The results achieved, using the SNAP (spectral non-destructive assay platform) system, were generally within a few per cent of the true activities and gave confidence in the ability to allocate wastes to the correct categories in accordance with national legislation. This is important for reasons of public safety and also for minimisation of the amount of RSA (Radioactive Substances Act) Exempt material categorised as LLW (low level waste) as the UK's LLW storage capacity diminishes. PMID:21149939

  1. Distribution of radionuclides in an iron calibration standard for a free release measurement facility.

    PubMed

    Hult, Mikael; Stroh, Heiko; Marissens, Gerd; Tzika, Faidra; Lutter, Guillaume; Šurán, Jiri; Kovar, Petr; Skala, Lukas; Sud, Jaromír

    2016-03-01

    A Europallet-sized calibration standard composed of 12 grey cast iron tubes contaminated with (60)Co and (110m)Ag with a mass of 246kg was developed. As the tubes were produced through centrifugal casting it was of particular concern to study the distribution of radionuclides in the radial direction of the tubes. This was done by removing 72 small samples (swarf) of ~0.3g each on both the inside and outside of the tubes. All of the samples were measured in the underground laboratory HADES. PMID:26597655

  2. National Emission Standards for Hazardous Air Pollutants - Radionuclide Emissions, Calendar Year 2011

    SciTech Connect

    NSTec Ecological and Environmental Monitoring

    2012-06-19

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office operates the Nevada National Security Site (NNSS) and North Las Vegas Facility (NLVF). From 1951 through 1992, the NNSS was the continental testing location for U.S. nuclear weapons. The release of radionuclides from NNSS activities has been monitored since the initiation of atmospheric testing. Limitation to underground detonations after 1962 greatly reduced radiation exposure to the public surrounding the NNSS. After nuclear testing ended in 1992, NNSS radiation monitoring focused on detecting airborne radionuclides from historically contaminated soils. These radionuclides are derived from re-suspension of soil (primarily by wind) and emission of tritium-contaminated soil moisture through evapotranspiration. Low amounts of legacy-related tritium are also emitted to air at the NLVF, an NNSS support complex in North Las Vegas. To protect the public from harmful levels of man-made radiation, the Clean Air Act, National Emission Standards for Hazardous Air Pollutants (NESHAP) (Title 40 Code of Federal Regulations [CFR] Part 61 Subpart H) limits the release of radioactivity from a U.S. Department of Energy (DOE) facility to that which would cause 10 millirem per year (mrem/yr) effective dose equivalent to any member of the public. This limit does not include radiation unrelated to NNSS activities. Unrelated doses could come from naturally occurring radioactive elements, from sources such as medically or commercially used radionuclides, or from sources outside of the United States, such as the damaged Fukushima nuclear power plant in Japan. Radionuclides from the Fukushima nuclear power plant were detected at the NNSS in March 2011 and are discussed further in Section III. The NNSS demonstrates compliance with the NESHAP limit by using environmental measurements of radionuclide air concentrations at critical receptor locations. This method was approved by the EPA for use on the

  3. National Emission Standards for Hazardous Air Pollutants - Radionuclide Emissions, Calendar Year 2010

    SciTech Connect

    NSTec Ecological and Environmental Monitoring

    2011-06-30

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office operates the Nevada National Security Site (NNSS, formerly the Nevada Test Site) and North Las Vegas Facility (NLVF). From 1951 through 1992, the NNSS was the continental testing location for U.S. nuclear weapons. The release of radionuclides from NNSS activities has been monitored since the initiation of atmospheric testing. Limitation to underground detonations after 1962 greatly reduced radiation exposure to the public surrounding the NNSS. After nuclear testing ended in 1992, NNSS radiation monitoring focused on detecting airborne radionuclides from historically contaminated soils. These radionuclides are derived from re-suspension of soil (primarily by wind) and emission of tritium-contaminated soil moisture through evapotranspiration. Low amounts of tritium are also emitted to air at the NLVF, an NNSS support complex in North Las Vegas. To protect the public from harmful levels of man-made radiation, the Clean Air Act, National Emission Standards for Hazardous Air Pollutants (NESHAP) (Title 40 Code of Federal Regulations [CFR] Part 61 Subpart H) (CFR, 2010a) limits the release of radioactivity from a U.S. Department of Energy (DOE) facility to that which would cause 10 millirem per year (mrem/yr) effective dose equivalent to any member of the public. This limit does not include radiation unrelated to NNSS activities. Unrelated doses could come from naturally occurring radioactive elements, from sources such as medically or commercially used radionuclides, or from sources outside of the United States, such as those from the damaged Fukushima nuclear power plant in Japan. Because this report is intended to discuss radioactive air emissions during calendar year 2010, data on radionuclides in air from the 2011 Fukushima nuclear power plant releases are not presented but will be included in the report for calendar year 2011. The NNSS demonstrates compliance with the NESHAP

  4. Performance demonstration of 4πβ(LS)-γ coincidence counting system for standardization of radionuclides with complex decay scheme.

    PubMed

    Kulkarni, D B; Anuradha, R; Joseph, Leena; Kulkarni, M S; Tomar, B S

    2016-02-01

    A standardization of (134)Cs and (131)I was carried out in order to demonstrate the performance and applicability of the 4πβ(LS)-γ coincidence counting system for standardization of radionuclides with complex decay scheme. The coincidence analyzer, capable of analyzing coincidence between beta and two gamma windows simultaneously, was developed and used for the standardization. The use of this dual coincidence analyzer has reduced the total experimental time by half. The activity concentrations obtained using the 4πβ(LS)-γ coincidence counting system, a 4πβ(PC)-γ coincidence counting system, and the CIEMAT/NIST method are in excellent agreement with each other within uncertainty limits and hence demonstrates its performance for standardization of radionuclides decaying with complex decay scheme. Hence use of this 4πβ(LS)-γ coincidence counting system can be an alternative method suitable to standardize radionuclides with complex decay scheme with acceptable precision.

  5. Performance demonstration of 4πβ(LS)-γ coincidence counting system for standardization of radionuclides with complex decay scheme.

    PubMed

    Kulkarni, D B; Anuradha, R; Joseph, Leena; Kulkarni, M S; Tomar, B S

    2016-02-01

    A standardization of (134)Cs and (131)I was carried out in order to demonstrate the performance and applicability of the 4πβ(LS)-γ coincidence counting system for standardization of radionuclides with complex decay scheme. The coincidence analyzer, capable of analyzing coincidence between beta and two gamma windows simultaneously, was developed and used for the standardization. The use of this dual coincidence analyzer has reduced the total experimental time by half. The activity concentrations obtained using the 4πβ(LS)-γ coincidence counting system, a 4πβ(PC)-γ coincidence counting system, and the CIEMAT/NIST method are in excellent agreement with each other within uncertainty limits and hence demonstrates its performance for standardization of radionuclides decaying with complex decay scheme. Hence use of this 4πβ(LS)-γ coincidence counting system can be an alternative method suitable to standardize radionuclides with complex decay scheme with acceptable precision. PMID:26678524

  6. National Emission Standards for Hazardous Air Pollutants - Radionuclide Emissions Calendar Year 2009

    SciTech Connect

    NSTec Ecological and Environmental Monitoring

    2010-06-11

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office operates the Nevada Test Site (NTS) and North Las Vegas Facility (NLVF). From 1951 through 1992, the NTS was the continental testing location for U.S. nuclear weapons. The release of radionuclides from NTS activities has been monitored since the initiation of atmospheric testing. Limitation to underground detonations after 1962 greatly reduced radiation exposure to the public surrounding the NTS. After nuclear testing ended in 1992, NTS radiation monitoring focused on detecting airborne radionuclides from historically contaminated soils. These radionuclides are derived from re-suspension of soil (primarily by wind) and emission of tritium-contaminated soil moisture through evapotranspiration. Low amounts of tritium were also emitted to air at the NLVF, an NTS support complex in North Las Vegas. To protect the public from harmful levels of man-made radiation, the Clean Air Act, National Emission Standards for Hazardous Air Pollutants (NESHAP) (Title 40 Code of Federal Regulations [CFR] Part 61 Subpart H) limits the release of radioactivity from a U.S. Department of Energy facility to 10 millirem per year (mrem/yr) effective dose equivalent to any member of the public. This limit does not include radiation not related to NTS activities. Unrelated doses could come from naturally occurring radioactive elements or from sources such as medically or commercially used radionuclides. The NTS demonstrates compliance with the NESHAP limit by using environmental measurements of radionuclide air concentrations at critical receptor locations. This method was approved by the U.S. Environmental Protection Agency for use on the NTS in 2001 and has been the sole method used since 2005. Six locations on the NTS have been established to act as critical receptor locations to demonstrate compliance with the NESHAP limit. These locations are actually pseudo-critical receptor stations, because no

  7. Elementary and Secondary Schools Under the Fair Labor Standards Act.

    ERIC Educational Resources Information Center

    Employment Standards Administration (DOL), Washington, DC. Wage and Hour Div.

    This pamphlet provides general information and guidelines concerning the application of the federal Fair Labor Standards Act to employees of elementary and secondary schools, as of January 1974. Separate short sections of the pamphlet examine various provisions of the act, emphasizing their impact on employer-employee relations in the schools.…

  8. An automated secondary standard for calibrating liquid flowmeters

    NASA Technical Reports Server (NTRS)

    Hobart, H. F.

    1976-01-01

    A secondary working standard of flow calibration has been developed to be used in place of a primary weight-time standard, and which can thereby effect a 75 percent reduction in calibration time while maintaining acceptable accuracies. The secondary standard uses six previously calibrated turbine-type flowmeters built into two manifold systems containing automatically switched flow valves. The pair of systems is capable of covering the flow range of 0.0004 to 19 l/s (0.007 to 300 gpm) with the uncertainty in volume flow rate not exceeding + or - 0.25 percent over the range of 0.06 to 19 l/s and not exceeding + or - 0.5 percent over the range 0.0004 to 0.06 1/s. Data reduction and plotting of results are by computer.

  9. An automated secondary standard for calibrating liquid flowmeters

    NASA Technical Reports Server (NTRS)

    Hobart, H. F.

    1976-01-01

    A secondary working standard of flow calibration has been developed to be used in place of a primary weight-time standard, and which can thereby effect a 75 percent reduction in calibration time while maintaining acceptable accuracies. The secondary standard uses six previously calibrated turbine-type flowmeters built into two manifold systems containing automatically switched flow valves. The pair of systems is capable of covering the flow range of 0.0004 to 19 1/s (0.007 to 300 gpm) with the uncertainty in volume flow rate not exceeding plus or minus 0.25 percent over the range 0.06 to 19 1/s and not exceeding plus or minus 0.5 percent over the range 0.0004 to 0.06 1/s. Data reduction and plotting of results are by computer.

  10. National Emission Standards for Hazardous Air Pollutants - Radionuclide Emissions Calendar Year 2012

    SciTech Connect

    Warren, R.

    2013-06-10

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) operates the Nevada National Security Site (NNSS) and North Las Vegas Facility (NLVF). From 1951 through 1992, the NNSS was the continental testing location for U.S. nuclear weapons. The release of radionuclides from NNSS activities has been monitored since the initiation of atmospheric testing. Limitation to underground detonations after 1962 greatly reduced radiation exposure to the public surrounding the NNSS. After nuclear testing ended in 1992, NNSS radiation monitoring focused on detecting airborne radionuclides from historically contaminated soils. These radionuclides are derived from re-suspension of soil (primarily by wind) and emission of tritium-contaminated soil moisture through evapotranspiration. Low amounts of legacy-related tritium are also emitted to air at the NLVF, an NNSS support complex in North Las Vegas. To protect the public from harmful levels of man-made radiation, the Clean Air Act, National Emission Standards for Hazardous Air Pollutants (NESHAP) (Title 40 Code of Federal Regulations [CFR] Part 61 Subpart H) (CFR 2010a) limits the release of radioactivity from a U.S. Department of Energy (DOE) facility to that which would cause 10 millirem per year (mrem/yr) effective dose equivalent to any member of the public. This limit does not include radiation unrelated to NNSS activities. Unrelated doses could come from naturally occurring radioactive elements, from sources such as medically or commercially used radionuclides, or from sources outside of the United States, such as the damaged Fukushima nuclear power plant in Japan in 2011. NNSA/NFO demonstrates compliance with the NESHAP limit by using environmental measurements of radionuclide air concentrations at critical receptor locations on the NNSS (U.S. Environmental Protection Agency [EPA] and DOE 1995). This method was approved by the EPA for use on the NNSS in 2001 (EPA 2001a) and has

  11. National Emission Standards for Hazardous Air Pollutants - Radionuclide Emissions Calendar Year 2013

    SciTech Connect

    Warren, R.

    2014-06-04

    The U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) operates the Nevada National Security Site (NNSS) and North Las Vegas Facility (NLVF). From 1951 through 1992, the NNSS was the continental testing location for U.S. nuclear weapons. The release of radionuclides from NNSS activities has been monitored since the initiation of atmospheric testing. Limitations to underground detonations after 1962 greatly reduced radiation exposure to the public surrounding the NNSS. After nuclear testing ended in 1992, NNSS radiation monitoring focused on detecting airborne radionuclides from historically contaminated soils. These radionuclides are derived from re-suspension of soil (primarily by wind) and emission of tritium-contaminated soil moisture through evapotranspiration. Low amounts of legacy-related tritium are also emitted to air at the NLVF, an NNSS support complex in North Las Vegas. To protect the public from harmful levels of man-made radiation, the Clean Air Act, National Emission Standards for Hazardous Air Pollutants (NESHAP) (Title 40 Code of Federal Regulations [CFR] Part 61 Subpart H) (CFR 2010a) limits the release of radioactivity from a U.S. Department of Energy (DOE) facility to that which would cause 10 millirem per year (mrem/yr) effective dose equivalent to any member of the public. This limit does not include radiation unrelated to NNSS activities. Unrelated doses could come from naturally occurring radioactive elements, from sources such as medically or commercially used radionuclides, or from sources outside of the United States, such as the damaged Fukushima nuclear power plant in Japan in 2011. NNSA/NFO demonstrates compliance with the NESHAP limit by using environmental measurements of radionuclide air concentrations at critical receptor locations on the NNSS (U.S. Environmental Protection Agency [EPA] and DOE 1995). This method was approved by the EPA for use on the NNSS in 2001 (EPA 2001a) and has

  12. Radionuclide hepatobiliary imaging: nonvisualization of the gallbladder secondary to prolonged fasting

    SciTech Connect

    Larsen, M.J.; Klingensmith, W.C. III; Kuni, C.C.

    1982-11-01

    Radionuclide hepatobiliary imaging demonstrated nonvisualization of the gallbladder in four patients who were studied after fasting from 14 hr to 12 days. Two patients subsequently had normal gallbladders at autopsy, and two gave normal gallbladder visualization on repeat imaging studies after fasts of 2 to 3 hr. These findings suggest that prolonged fasting may be a cause for nonvisualization of a normal gallbladder.

  13. Four-Color Photometry of Standards and Secondary Standards: Single Channel Observations

    NASA Astrophysics Data System (ADS)

    Philip, A. G. D.

    2004-05-01

    Now that no more observations are being added to my catalog of four-color photometry, corrections have been made by comparing the magnitudes of some of the brighter standard stars from night to night and bringing them to a common zeropoint. The table in the poster paper presents the final, corrected, four-color indices for two sets of stars. The first set contains those standard stars which have been observed ten or more times. The range in the number of observations is from 10 to 139, with an average of 34. The probable errors of the catalog observations for the standard stars are ± 0.003, 0.007, 0.005 and the probable errors relative to the published values of the standards (Crawford & Barnes 1970 AJ 73, 978) are ± 0.002, 0.004, 0.004 in (b-y), c1 and m1, respectively. The second set contains secondary standards. Again the number of observations starts at 10 and runs up to 168 with an average of 41. The probable errors of the observations are ± 0.005, 0.010, 0.008 and the probable errors relative to the stars listed in Hauck & Mermilliod (A&AS 129, 431) are ± 0.003, 0.004, 0.007 in (b-y), c1 and m1. The secondary standards range in magnitude y from 5.09 to 10.82. The stars are well spaced in right ascension in both the northern and southern hemispheres. About a dozen of the secondary standard stars are field horizontal-branch stars. The observations were made over a period of 21 years with 41 runs at KPNO, 24 at CTIO, 3 at Mount Wilson, 2 at Steward Observatory and 1 at ESO. A number of people participated in some of these observations and I would like to acknowledge Donald Hayes, John Drilling, Saul Adelman, Larry Relyea, Linda Tifft Matlock and Pascal Dubois for their help. The observatories listed above a thanked for assigning the observing time. Part of this work was supported by grants from the National Science Foundation.

  14. Characterization of FEL Lamps as Secondary Standard of Luminous Intensity

    NASA Astrophysics Data System (ADS)

    Junior, Antonio F. G. Ferreira; Machado, Ilomar E. C.

    2008-04-01

    This work presents a study comparing the drift during seasoning of four of 1000W FEL-type lamp regarding the use of theses lamps as secondary luminous intensity standard. Three of these lamps are manufactured by Philips and the other lamp is manufactured by ORIEL. The lamps seasoning takes normally 30 hours and during the seasoning period relative drift of the lamp luminous intensity, lamp current and voltage are measured at each 5 minutes. The correlated color temperature of the lamps is measured at the end of lamp seasoning period. The luminous intensity is measured using a 4 1/2 digits photometer with thermal stabilized detector head, the lamp voltage is measured using a 6 1/2 digits voltmeter and the current is measured and controlled by a calibrated current power source shunt. The lamp sockets are adapted to a cinematic positioning device which is placed on an adjustable mounting device. A cross target is used as reference for alignment with a He-Ne Laser. In the 1st group of three lamps from Philips the minimum relative drift in luminous intensity per hour at the end of seasoning period was 0,0075 percent and the maximum relative drift was 0,02 percent. Voltage relative drift of the lamps were very similar in shape on the last few hours of the seasoning period, but different for one lamp at the beginning. The lamp current remained practically constant at 8 A which was the current adjusted in the current power source. One lamp had the luminous intensity calibrated by the National Institute of Metrology from Argentina and is used as a transfer standard for the other lamps.

  15. 40 CFR 50.15 - National primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for ozone. 50.15 Section 50.15 Protection of Environment ENVIRONMENTAL....15 National primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone (O3) is 0.075 parts...

  16. 40 CFR 50.15 - National primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... air quality standards for ozone. 50.15 Section 50.15 Protection of Environment ENVIRONMENTAL....15 National primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone (O3) is 0.075 parts...

  17. 40 CFR 50.15 - National primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... air quality standards for ozone. 50.15 Section 50.15 Protection of Environment ENVIRONMENTAL....15 National primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone (O3) is 0.075 parts...

  18. 40 CFR 50.15 - National primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... air quality standards for ozone. 50.15 Section 50.15 Protection of Environment ENVIRONMENTAL....15 National primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone (O3) is 0.075 parts...

  19. 40 CFR 50.15 - National primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... air quality standards for ozone. 50.15 Section 50.15 Protection of Environment ENVIRONMENTAL....15 National primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone (O3) is 0.075 parts...

  20. 40 CFR 50.16 - National primary and secondary ambient air quality standards for lead.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... air quality standards for lead. 50.16 Section 50.16 Protection of Environment ENVIRONMENTAL PROTECTION... National primary and secondary ambient air quality standards for lead. (a) The national primary and secondary ambient air quality standards for lead (Pb) and its compounds are 0.15 micrograms per cubic...

  1. 40 CFR 50.12 - National primary and secondary ambient air quality standards for lead.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... air quality standards for lead. 50.12 Section 50.12 Protection of Environment ENVIRONMENTAL PROTECTION... National primary and secondary ambient air quality standards for lead. (a) National primary and secondary ambient air quality standards for lead and its compounds, measured as elemental lead by a reference...

  2. 40 CFR 50.6 - National primary and secondary ambient air quality standards for PM10.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for PM10. 50.6 Section 50.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.6 National primary and secondary ambient air quality standards for PM10. (a) The level of the...

  3. 40 CFR 50.16 - National primary and secondary ambient air quality standards for lead.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for lead. 50.16 Section 50.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.16 National primary and secondary ambient air quality standards for lead. (a) The national primary...

  4. 40 CFR 50.12 - National primary and secondary ambient air quality standards for lead.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for lead. 50.12 Section 50.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.12 National primary and secondary ambient air quality standards for lead. (a) National primary and...

  5. 77 FR 8575 - National Emissions Standards for Hazardous Air Pollutants: Secondary Aluminum Production

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... February 14, 2012 Part V Environmental Protection Agency 40 CFR Part 63 National Emissions Standards for... 63 RIN 2060-AQ40 National Emissions Standards for Hazardous Air Pollutants: Secondary Aluminum... proposing amendments to the national emissions standards for hazardous air pollutants for Secondary...

  6. 1996 Idaho National Engineering and Environmental Laboratory (INEEL) National Emissions Standards for Hazardous Air Pollutants (NESHAPs) -- Radionuclides. Annual report

    SciTech Connect

    1997-06-01

    Under Section 61.94 of Title 40, Code of Federal Regulations (CFR), Part 61, Subpart H, ``National Emission Standards for Emissions of Radionuclides Other Than Radon From Department of Energy Facilities,`` each Department of Energy (DOE) facility must submit an annual report documenting compliance. This report addresses the Section 61.94 reporting requirements for operations at the Idaho National Engineering and Environmental Laboratory (INEEL) for calendar year (CY) 1996. The Idaho Operations Office of the DOE is the primary contact concerning compliance with the National Emission Standards for Hazardous Air Pollutants (NESHAPs) at the INEEL. For calendar year 1996, airborne radionuclide emissions from the INEEL operations were calculated to result in a maximum individual dose to a member of the public of 3.14E-02 mrem (3.14E-07 Sievert). This effective dose equivalent (EDE) is well below the 40 CFR 61, Subpart H, regulatory standard of 10 mrem per year (1.0E-04 Sievert per year).

  7. State Secondary Career and Technical Education Standards: Creating a Framework from a Patchwork of Policies

    ERIC Educational Resources Information Center

    Castellano, Marisa; Harrison, Linda; Schneider, Sherrie

    2008-01-01

    Many states are currently working to define secondary career and technical education (CTE) content standards that specify the knowledge and skills students are expected to master in CTE program areas. This study explores the progress and status of states in developing statewide secondary CTE standards systems. An exhaustive online query of CTE…

  8. 76 FR 38591 - National Emission Standards for Hazardous Air Pollutants: Secondary Lead Smelting; Extension of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... the National Emissions Standards for Hazardous Air Pollutants for Secondary Lead Smelting (76 FR 29032... Standards for Hazardous Air Pollutants: Secondary Lead Smelting, was published May 19, 2011 (76 FR 29032... current rule. DATES: Comments on the proposed rule published May 19, 2011 (76 FR 29032) must be...

  9. An automated ionization chamber for secondary radioactivity standards.

    PubMed

    Fitzgerald, R

    2010-01-01

    I report on the operation and characterization of a new ionization chamber system, "AUTOIC", featuring a commercial digital electrometer and a commercial robotic sample changer. The relative accuracy of the electrometer was improved significantly beyond the manufacturer's specifications through an in-house calibration of the various ranges, applied via software. The measurement precision and repeatability of the system have been determined by measuring multiple samples of the same radionuclide over the span of two or three years. The linearity of the system was examined by following the decay of (99m)Tc, (99)Mo and (133)Xe sources for up to 19 half-lives and determining half-life values. All of these values agree with the accepted literature values, within their combined uncertainties.

  10. NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS (NESHAP) SUBPART H RADIONUCLIDES POTENTIAL TO EMIT CALCULATIONS

    SciTech Connect

    EARLEY JN

    2008-07-23

    This document provides an update of the status of stacks on the Hanford Site and the potential radionuclide emissions, i.e., emissions that could occur with no control devices in place. This review shows the calculations that determined whether the total effective dose equivalent (TEDE) received by the maximum public receptor as a result of potential emissions from any one of these stacks would exceed 0.1 millirem/year. Such stacks require continuous monitoring of the effluent, or other monitoring, to meet the requirements of Washington Administrative code (WAC) 246-247-035(1)(a)(ii) and WAC 246-247-075(1), -(2), and -(6). This revised update reviews the potential-to-emit (PTE) calculations of 31 stacks for Fluor Hanford, Inc. Of those 31 stacks, 11 have the potential to cause a TEDE greater than 0.1 mrem/year.

  11. Hanford Site radionuclide national emission standards for hazardous air pollutants registered stack source assessment

    SciTech Connect

    Davis, W.E.; Barnett, J.M.

    1994-07-01

    On February 3, 1993, the US Department of Energy, Richland Operations Office received a Compliance Order and Information Request from the Director of the Air and Toxics Division of the US Environmental Protection Agency,, Region 10. The Compliance Order requires the Richland Operations Office to evaluate all radionuclide emission points at the Hanford Site . The evaluation also determined if the effective dose equivalent from any of these stack emissions exceeded 0.1 mrem/yr, which will require the stack to have continuous monitoring. The result of this assessment identified a total of 16 stacks as having potential emissions that,would cause an effective dose equivalent greater than 0.1 mrem/yr.

  12. 1997 Idaho National Engineering and Environmental Laboratory (INEEL) National Emission Standards for Hazardous Air Pollutants (NESHAPs) -- Radionuclides annual report

    SciTech Connect

    1998-06-01

    Under Section 61.94 of Title 40, Code of Federal Regulations (CFR), Part 61, Subpart H, National Emission Standards for Emissions of Radionuclides Other Than Radon From Department of Energy Facilities, each Department of Energy (DOE) facility must submit an annual report documenting compliance. This report addresses the Section 61.94 reporting requirements for operations at the Idaho National Engineering and Environmental Laboratory (INEEL) for calendar year (CY) 1997. Section 1 of this report provides an overview of the INEEL facilities and a brief description of the radioactive materials and processes at the facilities. Section 2 identifies radioactive air effluent release points and diffuse sources at the INEEL and actual releases during 1997. Section 2 also describes the effluent control systems for each potential release point. Section 3 provides the methodology and EDE calculations for 1997 INEEL radioactive emissions.

  13. The Standardization of American Schooling: Linking Secondary and Higher Education, 1870-1910. Secondary Education in a Changing World

    ERIC Educational Resources Information Center

    VanOverbeke, Marc A.

    2008-01-01

    This book explores the efforts of educational reformers who sought to link secondary and higher education in the decades after 1870. Through various state, regional, and national initiatives, these reformers created a hierarchical system, laid the foundation for a growing standardization in education, and influenced who would have access to…

  14. Secondary Social Studies Teachers' Time Commitment When Addressing the Common Core State Standards

    ERIC Educational Resources Information Center

    Kenna, Joshua L.; Russell, William Benedict, III

    2015-01-01

    In 2010 the Common Core State Standards (CCSS) were officially released in America for mathematics and English language arts and soon adopted by 45 of the 50 states. However, within the English langue arts domain there were standards intended for secondary social studies teachers under the title, Common Core State Standards for English Language…

  15. 77 FR 16547 - Radionuclide National Emission Standards for Hazardous Air Pollutants; Notice of Construction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-21

    ... for Radon Emissions from Underground Uranium Mines (Subpart B) and 40 CFR part 61, subpart W, National Emission Standards for Radon Emissions from Operating Mill Tailings (Subpart W). EPA Region 8 issued...

  16. Secondary Social Studies Teachers' Experiences Implementing Common Core State Literacy Standards: A Phenomenological Study

    ERIC Educational Resources Information Center

    Webb, Krista Faith Huskey

    2014-01-01

    The purpose of this phenomenological study was to examine the experiences of secondary social studies teachers who implemented Common Core State Standards for English Language Arts & Literacy in history/social studies, science and technical subjects in social studies courses requiring End of Course Tests at secondary schools in one suburban…

  17. Secondary Student Motivation Orientations and Standards-Based Achievement Outcomes

    ERIC Educational Resources Information Center

    Meyer, Luanna H.; McClure, John; Walkey, Frank; Weir, Kirsty F.; McKenzie, Lynanne

    2009-01-01

    Background: Individual student characteristics such as competence motivation, achievement values, and goal orientations have been related in meaningful ways to task attainment. The standards-based National Certificate of Educational Achievement (NCEA) was developed in New Zealand with the intention of strengthening connections between student…

  18. FCS National Standards: Do They Underpin Secondary Curriculum?

    ERIC Educational Resources Information Center

    Smith, Bettye P.; Hall, Helen C.; Jones, Karen H.

    2005-01-01

    This study focuses on the seven standards that are included in a comprehensive (family-oriented) FCS program: (1) Family; (2) Nutrition and Wellness; (3) Human Development; (4) Interpersonal relationships; (5) Career, Community, and Family Connections; (6) Parenting; and (7) Family and Community Services. The study was conducted to better…

  19. Radionuclide Therapy

    NASA Astrophysics Data System (ADS)

    Zalutsky, M. R.

    Radionuclide therapy utilizes unsealed sources of radionuclides as a treatment for cancer or other pathological conditions such as rheumatoid arthritis. Radionuclides that decay by the emission of β and α particles, as well as those that emit Auger electrons, have been used for this purpose. In this chapter, radiochemical aspects of radionuclide therapy, including criteria for radionuclide selection, radionuclide production, radiolabeling chemistry, and radiation dosimetry are discussed.

  20. 77 FR 555 - National Emissions Standards for Hazardous Air Pollutants From Secondary Lead Smelting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... (62 FR 32216). The standards are codified at 40 CFR part 63, subpart X. The secondary lead smelting... January 5, 2012 Part II Environmental Protection Agency 40 CFR Part 63 National Emissions Standards for... / Thursday, January 5, 2012 / Rules and Regulations#0;#0; ] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part...

  1. 40 CFR 50.5 - National secondary ambient air quality standard for sulfur oxides (sulfur dioxide).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standard for sulfur oxides (sulfur dioxide). 50.5 Section 50.5 Protection of Environment ENVIRONMENTAL....5 National secondary ambient air quality standard for sulfur oxides (sulfur dioxide). (a) The level... than 0.05 ppm shall be rounded up). (b) Sulfur oxides shall be measured in the ambient air as...

  2. 40 CFR 50.5 - National secondary ambient air quality standard for sulfur oxides (sulfur dioxide).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... standard for sulfur oxides (sulfur dioxide). 50.5 Section 50.5 Protection of Environment ENVIRONMENTAL....5 National secondary ambient air quality standard for sulfur oxides (sulfur dioxide). (a) The level... than 0.05 ppm shall be rounded up). (b) Sulfur oxides shall be measured in the ambient air as...

  3. 40 CFR 50.5 - National secondary ambient air quality standard for sulfur oxides (sulfur dioxide).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... standard for sulfur oxides (sulfur dioxide). 50.5 Section 50.5 Protection of Environment ENVIRONMENTAL....5 National secondary ambient air quality standard for sulfur oxides (sulfur dioxide). (a) The level... than 0.05 ppm shall be rounded up). (b) Sulfur oxides shall be measured in the ambient air as...

  4. 40 CFR 50.5 - National secondary ambient air quality standard for sulfur oxides (sulfur dioxide).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standard for sulfur oxides (sulfur dioxide). 50.5 Section 50.5 Protection of Environment ENVIRONMENTAL....5 National secondary ambient air quality standard for sulfur oxides (sulfur dioxide). (a) The level... than 0.05 ppm shall be rounded up). (b) Sulfur oxides shall be measured in the ambient air as...

  5. 40 CFR 50.5 - National secondary ambient air quality standard for sulfur oxides (sulfur dioxide).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... standard for sulfur oxides (sulfur dioxide). 50.5 Section 50.5 Protection of Environment ENVIRONMENTAL....5 National secondary ambient air quality standard for sulfur oxides (sulfur dioxide). (a) The level... than 0.05 ppm shall be rounded up). (b) Sulfur oxides shall be measured in the ambient air as...

  6. 40 CFR 50.13 - National primary and secondary ambient air quality standards for PM2.5.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false National primary and secondary ambient air quality standards for PM2.5. 50.13 Section 50.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.13 National primary and secondary ambient...

  7. 40 CFR 50.7 - National primary and secondary ambient air quality standards for PM2.5.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false National primary and secondary ambient air quality standards for PM2.5. 50.7 Section 50.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.7 National primary and secondary ambient...

  8. "Standards"-based Mathematics Curricula and Secondary Students' Performance on Standardized Achievement Tests

    ERIC Educational Resources Information Center

    Harwell, Michael R.; Post, Thomas R.; Maeda, Yukiko; Davis, Jon D.; Cutler, Arnold L.; Andersen, Edwin; Kahan, Jeremy A.

    2007-01-01

    The current study examined the mathematical achievement of high school students enrolled for 3 years in one of three NSF funded "Standards"-based curricula (IMP, CMIC, MMOW). The focus was on traditional topics in mathematics as measured by subtests of a standardized achievement test and a criterion-referenced test of mathematics achievement.…

  9. 40 CFR 50.10 - National 8-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ambient air quality standards for ozone. 50.10 Section 50.10 Protection of Environment ENVIRONMENTAL....10 National 8-hour primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone, measured by...

  10. 40 CFR 50.10 - National 8-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ambient air quality standards for ozone. 50.10 Section 50.10 Protection of Environment ENVIRONMENTAL....10 National 8-hour primary and secondary ambient air quality standards for ozone. (a) The level of the national 8-hour primary and secondary ambient air quality standards for ozone, measured by...

  11. 40 CFR 50.7 - National primary and secondary ambient air quality standards for PM2.5.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for PM2.5. 50.7 Section 50.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.7 National primary and secondary ambient air quality standards for PM2.5. (a) The national primary...

  12. 40 CFR 50.13 - National primary and secondary ambient air quality standards for PM2.5.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for PM2.5. 50.13 Section 50.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS § 50.13 National primary and secondary ambient air quality standards for PM2.5. (a) The national...

  13. Jordanian Vocational, Secondary Education Teachers and Acquisition of the National Professional Standards

    ERIC Educational Resources Information Center

    Al-Dajeh, Hesham I.

    2012-01-01

    The main purpose of this study was to estimate the level of acquisition of the Jordanian national professional standards by vocational, secondary education teachers. Two hundred teachers participated in the study. The data were collected by questionnaire and analyzed using SPSS version 15.0. Questionnaire validity was assessed by content validity,…

  14. Applying Standards for Leaders to the Selection of Secondary School Principals

    ERIC Educational Resources Information Center

    Wildy, Helen; Pepper, Coral; Guanzhong, Luo

    2011-01-01

    Purpose: The purpose of this paper is to report innovative research aimed at ascertaining whether standards for school leaders could be applied to the process of selecting senior secondary school principals for appointment. Specifically, psychometrically robust measures of performance are sought that would sufficiently differentiate performance to…

  15. Constructing Assessment Model of Primary and Secondary Educational Quality with Talent Quality as the Core Standard

    ERIC Educational Resources Information Center

    Chen, Benyou

    2014-01-01

    Quality is the core of education and it is important to standardization construction of primary and secondary education in urban (U) and rural (R) areas. The ultimate goal of the integration of urban and rural education is to pursuit quality urban and rural education. Based on analysing the related policy basis and the existing assessment models…

  16. Language Arts Core Curriculum: Secondary Core Curriculum Standards. Levels 7-12, Language Arts (Drama). Revised.

    ERIC Educational Resources Information Center

    Utah State Board of Education, Salt Lake City.

    This curriculum guide presents the core standards and objectives for level 7-12 language arts instruction in Utah. The curriculum guide begins with a statement of the elementary and secondary school program of studies and high school graduation requirements. After a brief statement on the importance of language arts and core curriculum standards…

  17. State Secondary CTE Standards: Developing a Framework out of a Patchwork of Policies

    ERIC Educational Resources Information Center

    Castellano, Marisa; Harrison, Linda; Schneider, Sherrie

    2007-01-01

    Many state educational administrators are currently working to define secondary career and technical education (CTE) content standards that specify the knowledge and skills students are expected to master in CTE program areas. The two-phase project on which this report is based explored (a) the progress and status of states in developing statewide…

  18. Radionuclide trap

    DOEpatents

    McGuire, Joseph C.

    1978-01-01

    The deposition of radionuclides manganese-54, cobalt-58 and cobalt-60 from liquid sodium coolant is controlled by providing surfaces of nickel or high nickel alloys to extract the radionuclides from the liquid sodium, and by providing surfaces of tungsten, molybdenum or tantalum to prevent or retard radionuclide deposition.

  19. Preservice Secondary Teachers Perceptions of College-Level Mathematics Content Connections with the Common Core State Standards for Mathematics

    ERIC Educational Resources Information Center

    Olson, Travis A.

    2016-01-01

    Preservice Secondary Mathematics Teachers (PSMTs) were surveyed to identify if they could connect early-secondary mathematics content (Grades 7-9) in the Common Core State Standards for Mathematics (CCSSM) with mathematics content studied in content courses for certification in secondary teacher preparation programs. Respondents were asked to…

  20. 40 CFR Appendix P to Part 50 - Interpretation of the Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Interpretation of the Primary and Secondary National Ambient Air Quality Standards for Ozone P Appendix P to Part 50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS Pt. 50, App. P Appendix P...

  1. Use and qualification of primary and secondary standards employed in quantitative ¹H NMR spectroscopy of pharmaceuticals.

    PubMed

    Rundlöf, Torgny; McEwen, Ian; Johansson, Monika; Arvidsson, Torbjörn

    2014-05-01

    Standards are required in quantitative NMR (qNMR) to obtain accurate and precise results. In this study acetanilide was established and used as a primary standard. Six other chemicals were selected as secondary standards: 3,4,5-trichloropyridine, dimethylterephthalate, maleic acid, 3-sulfolene, 1,4-bis(trimethylsilyl)benzene, and 1,3,5-trimethoxybenzene. The secondary standards were quantified using the primary standard acetanilide. A protocol for qualification and periodic checks of these secondary standards was developed, and used for evaluation of the stability of the compounds. Periodic monitoring of purity was performed for several years. The purity was higher than 99% for all secondary standards. All standards maintained the initial purity during the time period of monitoring, with very small variations in purity (0.3-0.4%). The selected secondary standards were shown to be suitable qNMR standards and that periodic requalification of the standards by qNMR ensures reliable analytical results. These standards have been used in our laboratory for compliance testing of pharmaceutical active substances and approved medicinal products as well as for analysis of suspected illegal medicines. In total more than 1000 samples have been tested using both internal and external standardization and examples are given.

  2. Use and qualification of primary and secondary standards employed in quantitative ¹H NMR spectroscopy of pharmaceuticals.

    PubMed

    Rundlöf, Torgny; McEwen, Ian; Johansson, Monika; Arvidsson, Torbjörn

    2014-05-01

    Standards are required in quantitative NMR (qNMR) to obtain accurate and precise results. In this study acetanilide was established and used as a primary standard. Six other chemicals were selected as secondary standards: 3,4,5-trichloropyridine, dimethylterephthalate, maleic acid, 3-sulfolene, 1,4-bis(trimethylsilyl)benzene, and 1,3,5-trimethoxybenzene. The secondary standards were quantified using the primary standard acetanilide. A protocol for qualification and periodic checks of these secondary standards was developed, and used for evaluation of the stability of the compounds. Periodic monitoring of purity was performed for several years. The purity was higher than 99% for all secondary standards. All standards maintained the initial purity during the time period of monitoring, with very small variations in purity (0.3-0.4%). The selected secondary standards were shown to be suitable qNMR standards and that periodic requalification of the standards by qNMR ensures reliable analytical results. These standards have been used in our laboratory for compliance testing of pharmaceutical active substances and approved medicinal products as well as for analysis of suspected illegal medicines. In total more than 1000 samples have been tested using both internal and external standardization and examples are given. PMID:24206940

  3. Characterization of 235U Targets for the Development of a Secondary Neutron Fluence Standard

    NASA Astrophysics Data System (ADS)

    Heyse, J.; Anastasiou, M.; Eykens, R.; Moens, A.; Plompen, A. J. M.; Schillebeeckx, P.; Sibbens, G.; Vanleeuw, D.; Wynants, R.

    2014-05-01

    The MetroFission project, a Joint Research Project within the European Metrology Research Program (EMRP), aims at addressing a number of metrological problems involved in the design of proposed Generation IV nuclear reactors. As part of this project a secondary neutron fluence standard is being developed and tested at the neutron time-of-flight facility GELINA of the JRC Institute for Reference Materials and Measurements (IRMM). This secondary standard will help to reach the neutron cross section measurement uncertainties required for the design of new generation power plants and fuel cycles. Such a neutron fluence device contains targets for which the neutron induced cross section is considered to be a standard. A careful preparation and characterization of these samples is an essential part of its development. In this framework a set of 235U targets has been produced by vacuum deposition of UF4 on aluminum backings by the target preparation laboratory at IRMM. These targets have been characterized for both their total mass and mass distribution over the sample area.

  4. Hanford Site radionuclide national emission standards for hazardous ari pollutants registered and and unregistered stack (powered exhaust) source assessment

    SciTech Connect

    Davis, W.E.

    1995-12-01

    On February 3, 1993, US DOE Richland Operations Office received a Compliance Order and Information Request from the Director of the Air and Toxics Div. of US EPA, Region X. The compliance order requires the Richland Operations Office to evaluate all radionuclide emission points at the Hanford site to determine which are subject to the continuous emission measurement requirements in Title 40, Code of Federal Regulations (CFR), Part 61, Subpart H, and to continuously measure radionuclide emissions in accordance with 40 CFR 61.93. The Information Request required The provision of a written compliance plan to meet the requirements of the compliance order. A compliance plan was submitted to EPA, Region X, on April 30, 1993. It set as one of the milestones, the complete assessment of the Hanford Site 84 stacks registered with the Washington State Department of Health, by December 17, 1993. This milestone was accomplished. The compliance plan also called for reaching a Federal Facility Compliance Agreement; this was reached on February 7, 1994, between DOE Richland Operations and EPA, Region X. The milestone to assess the unregistered stacks (powered exhaust) by August 31, 1994, was met. This update presents assessments for 72 registered and 22 unregistered stacks with potential emissions > 0.1 mrem/yr.

  5. 40 CFR Appendix P to Part 50 - Interpretation of the Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Secondary National Ambient Air Quality Standards for Ozone P Appendix P to Part 50 Protection of Environment... Air Quality Standards for Ozone 1. General (a) This appendix explains the data handling conventions... air quality standards for ozone (O3) specified in § 50.15 are met at an ambient O3 air...

  6. 40 CFR 50.9 - National 1-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-hour standards are codified in 40 CFR part 81. (c) EPA's authority under paragraph (b) of this section... ambient air quality standards for ozone. 50.9 Section 50.9 Protection of Environment ENVIRONMENTAL....9 National 1-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  7. 40 CFR Appendix P to Part 50 - Interpretation of the Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Secondary National Ambient Air Quality Standards for Ozone P Appendix P to Part 50 Protection of Environment... Air Quality Standards for Ozone 1. General (a) This appendix explains the data handling conventions... air quality standards for ozone (O3) specified in § 50.15 are met at an ambient O3 air...

  8. 40 CFR 50.9 - National 1-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...-hour standards are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.9 Section 50.9 Protection of Environment ENVIRONMENTAL....9 National 1-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  9. 40 CFR 50.9 - National 1-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...-hour standards are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.9 Section 50.9 Protection of Environment ENVIRONMENTAL....9 National 1-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  10. 40 CFR 50.9 - National 1-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-hour standards are codified in 40 CFR part 81. (c) EPA's authority under paragraph (b) of this section... ambient air quality standards for ozone. 50.9 Section 50.9 Protection of Environment ENVIRONMENTAL....9 National 1-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  11. 40 CFR 50.9 - National 1-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-hour standards are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.9 Section 50.9 Protection of Environment ENVIRONMENTAL....9 National 1-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  12. 75 FR 20595 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ... for Oxides of Nitrogen and Oxides of Sulfur: First External Review Draft (75 FR 11877; March 12, 2010... AGENCY Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides... a proposal addressing the nitrogen oxides (NO X ) and sulfur oxides (SO X ) secondary...

  13. Secondary calibration laboratory for ionizing radiation laboratory accreitation program National Institute of Standards and Technology National Voluntary Laboratory Accreditation Program

    SciTech Connect

    Martin, P.R.

    1993-12-31

    This paper presents an overview of the procedures and requirements for accreditation under the Secondary Calibration Laboratory for Ionizing Radiation Program (SCLIR LAP). The requirements for a quality system, proficiency testing and the onsite assessment are discussed. The purpose of the accreditation program is to establish a network of secondary calibration laboratories that can provide calibrations traceable to the primary national standards.

  14. Track structure simulation for positron emitters of physical interest. Part III: The case of the non-standard radionuclides

    NASA Astrophysics Data System (ADS)

    Le Loirec, C.; Champion, C.

    2007-11-01

    With the growth of clinical Positron Emission Tomography (PET) utilizations, new molecular tracers, able to aid in the assessment, therapy planning and monitoring of cancer patients, are synthesized. As suggested by some works reported in the literature, these newcomers may be positron emitting isotopes of lanthanium, 134La, iodine, 120I, 121I and 124I, arsenic, 72As and 74As, oxygen, 14O, and neon, 19Ne. In this work, we present an inter comparison of these eight radiopharmaceuticals which may be used in PET. To do that we have used a Monte Carlo simulation of positron following-up in water that we have adapted to the beta decay of radionuclides. We have also access to accurate spatial and energetic distributions of the potential PET radiopharmaceuticals under investigation here. The results are given in an analytical way and have been compared, when possible, with theoretical and experimental values available in the literature.

  15. 40 CFR Appendix I to Part 50 - Interpretation of the 8-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and Secondary National Ambient Air Quality Standards for Ozone I Appendix I to Part 50 Protection of... Secondary National Ambient Air Quality Standards for Ozone 1. General. This appendix explains the data... secondary ambient air quality standards for ozone specified in § 50.10 are met at an ambient ozone...

  16. 40 CFR Appendix I to Part 50 - Interpretation of the 8-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and Secondary National Ambient Air Quality Standards for Ozone I Appendix I to Part 50 Protection of... Secondary National Ambient Air Quality Standards for Ozone 1. General. This appendix explains the data... secondary ambient air quality standards for ozone specified in § 50.10 are met at an ambient ozone...

  17. 40 CFR Appendix I to Part 50 - Interpretation of the 8-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and Secondary National Ambient Air Quality Standards for Ozone I Appendix I to Part 50 Protection of... Secondary National Ambient Air Quality Standards for Ozone 1. General. This appendix explains the data... secondary ambient air quality standards for ozone specified in § 50.10 are met at an ambient ozone...

  18. 40 CFR Appendix I to Part 50 - Interpretation of the 8-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and Secondary National Ambient Air Quality Standards for Ozone I Appendix I to Part 50 Protection of... Secondary National Ambient Air Quality Standards for Ozone 1. General. This appendix explains the data... secondary ambient air quality standards for ozone specified in § 50.10 are met at an ambient ozone...

  19. Radionuclide cisternogram

    MedlinePlus

    ... please enable JavaScript. A radionuclide cisternogram is a nuclear scan test. It is used to diagnose problems ... damage. The amount of radiation used during the nuclear scan is very small. Almost all of the ...

  20. Source geometry factors for HDR 192Ir brachytherapy secondary standard well-type ionization chamber calibrations

    NASA Astrophysics Data System (ADS)

    Shipley, D. R.; Sander, T.; Nutbrown, R. F.

    2015-03-01

    Well-type ionization chambers are used for measuring the source strength of radioactive brachytherapy sources before clinical use. Initially, the well chambers are calibrated against a suitable national standard. For high dose rate (HDR) 192Ir, this calibration is usually a two-step process. Firstly, the calibration source is traceably calibrated against an air kerma primary standard in terms of either reference air kerma rate or air kerma strength. The calibrated 192Ir source is then used to calibrate the secondary standard well-type ionization chamber. Calibration laboratories are usually only equipped with one type of HDR 192Ir source. If the clinical source type is different from that used for the calibration of the well chamber at the standards laboratory, a source geometry factor, ksg, is required to correct the calibration coefficient for any change of the well chamber response due to geometric differences between the sources. In this work we present source geometry factors for six different HDR 192Ir brachytherapy sources which have been determined using Monte Carlo techniques for a specific ionization chamber, the Standard Imaging HDR 1000 Plus well chamber with a type 70010 HDR iridium source holder. The calculated correction factors were normalized to the old and new type of calibration source used at the National Physical Laboratory. With the old Nucletron microSelectron-v1 (classic) HDR 192Ir calibration source, ksg was found to be in the range 0.983 to 0.999 and with the new Isodose Control HDR 192Ir Flexisource ksg was found to be in the range 0.987 to 1.004 with a relative uncertainty of 0.4% (k = 2). Source geometry factors for different combinations of calibration sources, clinical sources, well chambers and associated source holders, can be calculated with the formalism discussed in this paper.

  1. 40 CFR 50.10 - National 8-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ozone NAAQS are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.10 Section 50.10 Protection of Environment ENVIRONMENTAL....10 National 8-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  2. 40 CFR 50.10 - National 8-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... with respect to the 1997 ozone NAAQS are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.10 Section 50.10 Protection of Environment ENVIRONMENTAL....10 National 8-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  3. 40 CFR 50.10 - National 8-hour primary and secondary ambient air quality standards for ozone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... with respect to the 1997 ozone NAAQS are codified in 40 CFR part 81. ... ambient air quality standards for ozone. 50.10 Section 50.10 Protection of Environment ENVIRONMENTAL....10 National 8-hour primary and secondary ambient air quality standards for ozone. (a) The level...

  4. 75 FR 57463 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... AGENCY Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides... Ambient Air Quality Standards for Oxides of Nitrogen and Oxides of Sulfur: Second External Review Draft... for oxides of nitrogen (NO X ) and oxides of sulfur (SO X ). Because NO X , SO X , and...

  5. 75 FR 11877 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... AGENCY Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides... Ambient Air Quality Standards for Oxides of Nitrogen and Oxides of Sulfur: First External Review Draft... (welfare-based) NAAQS for oxides of nitrogen (NO X ) and oxides of sulfur (SO X ). Because NO X , SO...

  6. Teaching a Standard-Based Communicative English Textbook Series to Secondary School Students in Egypt: Investigating Teachers' Practices and Beliefs

    ERIC Educational Resources Information Center

    Abdel Latif, Muhammad M. Mahmoud

    2012-01-01

    Since any standards-based reform is made to bring about an improvement in students' learning, it requires changes in teachers' practices as well. This study examined how a standards-based communicative curricular reform in general secondary school English in Egypt has changed teachers' classroom practices, and the factors influencing such…

  7. Guideline on the prevention of secondary central nervous system lymphoma: British Committee for Standards in Haematology.

    PubMed

    McMillan, Andrew; Ardeshna, Kirit M; Cwynarski, Kate; Lyttelton, Matthew; McKay, Pam; Montoto, Silvia

    2013-10-01

    The guideline group was selected to be representative of UK-based medical experts. Ovid MEDLINE, EMBASE and NCBI Pubmed were searched systematically for publications in English from 1980 to 2012 using the MeSH subheading 'lymphoma, CNS', 'lymphoma, central nervous system', 'lymphoma, high grade', 'lymphoma, Burkitt's', 'lymphoma, lymphoblastic' and 'lymphoma, diffuse large B cell' as keywords, as well as all subheadings. The writing group produced the draft guideline, which was subsequently revised by consensus by members of the Haemato-oncology Task Force of the British Committee for Standards in Haematology (BCSH). The guideline was then reviewed by a sounding board of ~50 UK haematologists, the BCSH and the British Society for Haematology (BSH) Committee and comments incorporated where appropriate. The 'GRADE' system was used to quote levels and grades of evidence, details of which can be found in Appendix I. The objective of this guideline is to provide healthcare professionals with clear guidance on the optimal prevention of secondary central nervous system (CNS) lymphoma. The guidance may not be appropriate to patients of all lymphoma sub-types and in all cases individual patient circumstances may dictate an alternative approach. Acronyms are defined at time of first use.

  8. Workshop in Support of the Secondary National Ambient Air Quality Standards for Nitrogen (NOx) and Sulfur Oxides (SOx)

    EPA Science Inventory

    EPA is announcing a workshop to discuss policy-relevant science to Inform EPA’s "Review of the Secondary National Ambient Air Quality Standards (NAAQS) for Oxides of Nitrogen and Sulfur" report. The workshop is being organized by EPA’s Office of Research and Development’s, Nation...

  9. 75 FR 70258 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Nitrogen and Oxides of Sulfur: Second External Review Draft (75 FR 57463, September 21, 2010). The EPA... a later date (75 FR 61486, October 5, 2010). The supplementary materials were: an errata sheet for... AGENCY Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and...

  10. Bypass, Augment, or Integrate: How Secondary Mathematics Teachers Address the Literacy Demands of Standards-Based Curriculum Materials

    ERIC Educational Resources Information Center

    Chandler-Olcott, Kelly; Doerr, Helen M.; Hinchman, Kathleen A.; Masingila, Joanna O.

    2015-01-01

    This 3-year qualitative study examined how 26 teachers in four U.S. secondary schools addressed the literacy demands of curriculum materials based on standards from the National Council of Teachers of Mathematics. It was grounded in sociocultural perspectives that encourage study of language in local contexts, including classrooms, communities,…

  11. The Relationship between Computer and Internet Use and Performance on Standardized Tests by Secondary School Students with Visual Impairments

    ERIC Educational Resources Information Center

    Zhou, Li; Griffin-Shirley, Nora; Kelley, Pat; Banda, Devender R.; Lan, William Y.; Parker, Amy T.; Smith, Derrick W.

    2012-01-01

    Introduction: The study presented here explored the relationship between computer and Internet use and the performance on standardized tests by secondary school students with visual impairments. Methods: With data retrieved from the first three waves (2001-05) of the National Longitudinal Transition Study-2, the correlational study focused on…

  12. Rapid apolipoprotein E radioimmunoassay using solid-phase staphylococcus protein. Use of pooled plasma as a secondary standard

    SciTech Connect

    Au, Y.P.T.; Bren, N.D.; Kottke, B.A.

    1986-07-16

    A rapid apolipoprotein E (apo E) radioimmunoassay, which requires a total of 24 hour incubation as compared to the usual 3-5 days, has been developed in their laboratory. Solid phase staphylococcus protein A was used to separate bound and unbound labeled antigen. Use of a pooled plasma (quality control sample) as a secondary standard to reduce interassay variation was also described.

  13. Investigation and Development of Competency Standards and Certification Requirements for Secondary-Level Vocational Foodservice Programs. Final Report.

    ERIC Educational Resources Information Center

    Usiewicz, Ronald A.

    An investigation ascertained, analyzed, and documented competency standards and certification requirements for secondary-level vocational food service programs. A literature review produced no instruments used in past studies to measure the attitudes of food service professionals toward task competencies. Six occupations were selected for the…

  14. A Comparison of Secondary Principals' Use of Data Systems to Increase Student Achievement in Mathematics as Measured by Standardized Assessments

    ERIC Educational Resources Information Center

    Williams, Joshua

    2011-01-01

    The pressure to meet the demands of "No Child Left Behind" (NCLB) Act coupled with poor results by secondary students on national assessments in mathematics have forced school principals to develop skill sets in the use of data in efforts to increase student performance on standardized assessments. The effective use of data by school principals…

  15. Radionuclide removal

    SciTech Connect

    Sorg, T.J.

    1991-01-01

    The U.S. Environmental Protection Agency proposed new and revised regulations on radionuclide contaminants in drinking water in June 1991. During the 1980's, the Drinking Water Research Division, USEPA conducted a research program to evaluate various technologies to remove radium, uranium and radon from drinking water. The research consisted of laboratory and field studies conducted by USEPA, universities and consultants. The paper summarizes the results of the most significant projects completed. General information is also presented on the general chemistry of the three radionuclides. The information presented indicates that the most practical treatment methods for radium are ion exchange and lime-soda softening and reverse osmosis. The methods tested for radon are aeration and granular activated carbon and the methods for uranium are anion exchange and reverse osmosis.

  16. [Secondary Standard Dosimetry Laboratory at the Ruder Bosković Institute, Zagreb].

    PubMed

    Vekić, Branko; Ban, Renata; Miljanić, Saveta

    2006-06-01

    The Secondary Standard Dosimetry Laboratory at the Ruder Bosković Institute (SSDL), Zagreb, Croatia, was set up over the last few years with a strong support by the International Atomic Energy Agency (IAEA) through the Technical Cooperation Project CRO/1/004, Establishing Calibration Services. The SSDL occupies two calibration rooms, each 9.6 m long and 6 m wide and each with proper air conditioning. Their walls are concrete and 1 m thick, and the entrance doors are plated with lead to protect the control rooms and the surroundings against radiation. In the first calibration room in the basement, there are two sealed sources which share the same, 6 m long calibration bench. A 30 TBq 60Co source on one side of the bench is used for calibrating ionising chambers and other high-dose radiation equipment. The irradiation unit on the other side of the bench combines two sealed sources, that is, a 740 MBq 137Cs source and a 185 MBq 60Co source, and is used for radiation protection purposes. It has three attenuators with nominal attenuations of x10, x100, and x1000. The second calibration room, which is just above the first, accommodates an X-ray unit (ISOVOLT 420, 40 kV to 300 kV, 1 mA to 20 mA) with a 5 m long calibration bench, aperture wheel assembly designed to modify the X-ray beam diameter to meet various configuration requirements for calibration instruments, a set of filter assemblies to control beam definition according to ISO 4037-3, and a half-value layer kit. PMID:16832975

  17. Radionuclide therapy beyond radioiodine.

    PubMed

    Gabriel, Michael

    2012-10-01

    For decades, Iodine-131 has been used for the treatment of patients with thyroid cancer. In recent years, increasingly, other radiopharmaceuticals are in clinical use in the treatment of various malignant diseases. Although in principle these therapies-as in all applications of radionuclides-special radiation protection measures are required, a separate nuclear medicine therapy department is not necessary in many cases due to the lower or lack of gamma radiation. In the following article, four different radionuclide therapies are more closely presented which are emerging in the last years. One of them is the "Peptide Receptor Radionuclide Therapy," the so-called PRRT in which radiolabeled somatostatin (SST)-receptor(R) ligands are used in patients with neuroendocrine tumors. On the basis of radiolabeled antibodies against CD20-positive cells, the so-called radioimmunotherapy is used in the treatment of certain forms of malignant lymphoma. In primary or secondary liver tumors, the (90)Y-labeled particles can be administered. Last but not the least, the palliative approach of bone-seeking radiopharmaceuticals is noted in patients with painful bone metastases.

  18. 40 CFR 52.1875 - Attainment dates for achieving the sulfur dioxide secondary standard.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....; Interlake, Inc.; Austin Power Co.; Diamond Crystal Salt Co.; The Goodyear Tire & Rubber Co.; The Gulf Oil Co... to achieve the secondary SO2 NAAQS by January 4, 1983: Diamond Crystal Salt; Firestone Tire &...

  19. 40 CFR 52.1875 - Attainment dates for achieving the sulfur dioxide secondary standard.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....; Interlake, Inc.; Austin Power Co.; Diamond Crystal Salt Co.; The Goodyear Tire & Rubber Co.; The Gulf Oil Co... to achieve the secondary SO2 NAAQS by January 4, 1983: Diamond Crystal Salt; Firestone Tire &...

  20. 40 CFR 52.1875 - Attainment dates for achieving the sulfur dioxide secondary standard.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....; Interlake, Inc.; Austin Power Co.; Diamond Crystal Salt Co.; The Goodyear Tire & Rubber Co.; The Gulf Oil Co... to achieve the secondary SO2 NAAQS by January 4, 1983: Diamond Crystal Salt; Firestone Tire &...

  1. 40 CFR 52.1875 - Attainment dates for achieving the sulfur dioxide secondary standard.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....; Interlake, Inc.; Austin Power Co.; Diamond Crystal Salt Co.; The Goodyear Tire & Rubber Co.; The Gulf Oil Co... to achieve the secondary SO2 NAAQS by January 4, 1983: Diamond Crystal Salt; Firestone Tire &...

  2. 40 CFR 52.1875 - Attainment dates for achieving the sulfur dioxide secondary standard.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....; Interlake, Inc.; Austin Power Co.; Diamond Crystal Salt Co.; The Goodyear Tire & Rubber Co.; The Gulf Oil Co... to achieve the secondary SO2 NAAQS by January 4, 1983: Diamond Crystal Salt; Firestone Tire &...

  3. CT-based quantitative SPECT for the radionuclide ²⁰¹Tl: experimental validation and a standardized uptake value for brain tumour patients.

    PubMed

    Willowson, Kathy; Bailey, Dale; Schembri, Geoff; Baldock, Clive

    2012-01-01

    We have previously reported on a method for reconstructing quantitative data from 99mTc single photon emission computed tomography (SPECT) images based on corrections derived from X-ray computed tomography, producing accurate results in both experimental and clinical studies. This has been extended for use with the radionuclide ²⁰¹Tl. Accuracy was evaluated with experimental phantom studies, including corrections for partial volume effects where necessary. The quantitative technique was used to derive standardized uptake values (SUVs) for ²⁰¹Tl evaluation of brain tumours. A preliminary study was performed on 26 patients using ²⁰¹Tl SPECT scans to assess residual tumor after surgery and then to monitor response to treatment, with a follow-up time of 18 months. Measures of SUVmax were made following quantitative processing of the data and using a threshold grown volume of interest around the tumour. Phantom studies resulted in the calculation of concentration values consistently within 4% of true values. No continuous relation was found between SUVmax (post-resection) and patient survival. Choosing an SUVmax cut-off of 1.5 demonstrated a difference in survival between the 2 groups of patients after surgery. Patients with an SUVmax<1.5 had a 70% survival rate over the first 10 months, compared with a 47% survival rate for those with SUVmax>1.5. This difference did not achieve significance, most likely due to the small study numbers. By 18 months follow-up this difference had reduced, with corresponding survival rates of 40% and 27%, respectively. Although this study involves only a small cohort, it has succeeded in demonstrating the possibility of an SUV measure for SPECT to help monitor response to treatment of brain tumours and predict survival. PMID:22375306

  4. CT-based quantitative SPECT for the radionuclide ²⁰¹Tl: experimental validation and a standardized uptake value for brain tumour patients.

    PubMed

    Willowson, Kathy; Bailey, Dale; Schembri, Geoff; Baldock, Clive

    2012-01-01

    We have previously reported on a method for reconstructing quantitative data from 99mTc single photon emission computed tomography (SPECT) images based on corrections derived from X-ray computed tomography, producing accurate results in both experimental and clinical studies. This has been extended for use with the radionuclide ²⁰¹Tl. Accuracy was evaluated with experimental phantom studies, including corrections for partial volume effects where necessary. The quantitative technique was used to derive standardized uptake values (SUVs) for ²⁰¹Tl evaluation of brain tumours. A preliminary study was performed on 26 patients using ²⁰¹Tl SPECT scans to assess residual tumor after surgery and then to monitor response to treatment, with a follow-up time of 18 months. Measures of SUVmax were made following quantitative processing of the data and using a threshold grown volume of interest around the tumour. Phantom studies resulted in the calculation of concentration values consistently within 4% of true values. No continuous relation was found between SUVmax (post-resection) and patient survival. Choosing an SUVmax cut-off of 1.5 demonstrated a difference in survival between the 2 groups of patients after surgery. Patients with an SUVmax<1.5 had a 70% survival rate over the first 10 months, compared with a 47% survival rate for those with SUVmax>1.5. This difference did not achieve significance, most likely due to the small study numbers. By 18 months follow-up this difference had reduced, with corresponding survival rates of 40% and 27%, respectively. Although this study involves only a small cohort, it has succeeded in demonstrating the possibility of an SUV measure for SPECT to help monitor response to treatment of brain tumours and predict survival.

  5. 77 FR 20217 - Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Sulfur

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... 1971. These standards were set at a level of 0.053 parts per million (ppm) as an annual average (36 FR... EPA proposed to retain the standards set in 1971 (49 FR 6866). After taking into account public comments, the EPA published the final decision to retain these standards in June 1985 (50 FR 25532)....

  6. Responsible Healthy Lifestyles, Levels 7-12. Secondary Core Curriculum Standards.

    ERIC Educational Resources Information Center

    Utah State Office of Education, Salt Lake City. Div. of Curriculum and Instruction.

    This guide presents the Utah elementary and secondary school program of studies and high school graduation requirements. A description is given of the responsible healthy lifestyles curriculum which is designed to integrate into a meaningful whole, medical, scientific, behavioral, and ethical knowledge, values, and practices which enhance a…

  7. WATER EXERCISE COMPARED TO LAND EXERCISE OR STANDARD CARE IN FEMALE CANCER SURVIVORS WITH SECONDARY LYMPHEDEMA.

    PubMed

    Lindquist, H; Enblom, A; Dunberger, G; Nyberg, T; Bergmark, K

    2015-06-01

    There are few studies showing that physical exercise can improve secondary lymphedema. We hypothesized that water exercise would be more effective than land exercise in reducing limb volume. Secondary objectives were joint movement, BMI, daily function, well-being, and body image. Limb volume was measured with circumference or was volumetric. Well-being and body image were measured with a study-specific questionnaire and daily function with DASH and HOOS questionnaires. Eighty-eight eligible patients with secondary lymphedema after breast or gynecological cancer participated in this controlled clinical intervention study. There was a higher proportion of women who participated in water exercises who reduced their secondary arm limb volume (p = 0.029), and there were also significant differences for BMI (p = 0.047) and self-reported frequency of swelling (p = 0.031) in the water exercise group after intervention. Women with arm lymphedema in the land exercise group improved DASH scores (p = 0.047) and outer rotation in the shoulder (p = 0.001). Our results suggest that to reduce objective and self-reported swelling, lymphedema patients may be offered water exercise training while to improve daily shoulder function, land exercises are preferred. To guide female cancer survivors with lymphedema to effective exercise resulting in reduced limb volume and improved function, adequate evidenced-based programs are needed. PMID:26714371

  8. Critical Supports for Secondary Educators in Common Core State Standard Implementation

    ERIC Educational Resources Information Center

    Ruchti, Wendy P.; Jenkins, Susan J.; Agamba, Joachim

    2013-01-01

    Teacher professional development (PD) is a complex, ongoing challenge as educational systems attempt to deliver excellent programming in pursuit of increased student achievement (Opfer and Pedder 2011). This article examines Idaho Total Instructional Alignment (TIA), a model for teacher PD that is currently being utilized in secondary schools…

  9. 77 FR 16987 - National Emission Standards for Hazardous Air Pollutants: Secondary Aluminum Production

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... for hazardous air pollutants for secondary aluminum production (77 FR 8576). The EPA is extending the... Aluminum Production AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of extension of public..., as well as review the test data for Group I furnaces. DATES: Comments. The public comment period...

  10. Social Studies. Levels 7-12. Revised. Secondary Core Curriculum Standards.

    ERIC Educational Resources Information Center

    Utah State Board of Education, Salt Lake City.

    The Utah 1991 revised social studies core curriculum guide specifies standards that must be completed by all students in grades 7-12 in order to meet Utah graduation standards. A review of the K-6 social studies curriculum also is included. The core curriculum is intended to represent ideas, concepts, and skills that provide a basic social studies…

  11. 76 FR 46083 - Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Sulfur

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... million (ppm) as an annual average (36 FR 8186). In 1982, EPA published Air Quality Criteria Document for... were based. In February 1984 EPA proposed to retain these standards (49 FR 6866). After taking into account public comments, EPA published the final decision to retain these standards in June 1985 (50...

  12. Using a Programmable JVS for evaluation of Zener voltage standards stability and secondary uncertainty under controlled temperature variation

    NASA Astrophysics Data System (ADS)

    de Andrade, Marcelo R.; Landim, Regis P.

    2016-07-01

    A study was carried out with two 732B model Zener-diode based electronic voltage standards, in order to analyze the influence of external temperature variation in their outputs. The temperature was controlled and the external variations were monitored. Inmetro Programmable Josephson Voltage Standard (PJVS) and Secondary systems were used for this purpose. Studies have shown that, despite the internal temperature control, there is a strong correlation between the external temperature and the internal thermistor value, for both Zeners. Inmetro Zener calibration uncertainty budget was revisited and the achieved uncertainties are ±0.09 μV (at 1.018 V) and ±0.4 μV (at 10 V), k=2.

  13. Compulsory Literacy and Numeracy Exit Standards for Senior Secondary Students: The Right Direction for Australia?

    ERIC Educational Resources Information Center

    Rice, Suzanne; Care, Esther; Griffin, Patrick

    2012-01-01

    An overview of positive and negative potential effects of the setting of compulsory exit-level standards in literacy and numeracy for students completing their final years of schooling is presented. The overview rests on studies completed primarily outside Australia, reflecting the reality of such practices not having been implemented widely in…

  14. Standardization of Lower Secondary Civic Education and Inequality of the Civic and Political Engagement of Students

    ERIC Educational Resources Information Center

    Witschge, Jacqueline; van de Werfhorst, Herman G.

    2016-01-01

    In this paper, the relation between the standardization of civic education and the inequality of civic engagement is examined. Using data from the International Civic and Citizenship Education Study 2009 among early adolescents and Eurydice country-level data, three-level analysis and variance function regression are applied to examine whether…

  15. "Raising Standards"& Deepening Inequality: Selection, League Tables, and Reform in Multiethnic Secondary Schools.

    ERIC Educational Resources Information Center

    Gillborn, David; Youdell, Deborah

    Although education in England is dominated by the rhetoric of "standards," this paper attempts to show that the overall shape and drive of English education reform has remained largely consistent. The annually published School Performance Tables continue to be assigned a special place in the reforms, as a means to and as an index of raising…

  16. Critical Review of Commercial Secondary Lithium-Ion Battery Safety Standards

    NASA Astrophysics Data System (ADS)

    Jones, Harry P.; Chapin, Thomas, J.; Tabaddor, Mahmod

    2010-09-01

    The development of Li-ion cells with greater energy density has lead to safety concerns that must be carefully assessed as Li-ion cells power a wide range of products from consumer electronics to electric vehicles to space applications. Documented field failures and product recalls for Li-ion cells, mostly for consumer electronic products, highlight the risk of fire, smoke, and even explosion. These failures have been attributed to the occurrence of internal short circuits and the subsequent thermal runaway that can lead to fire and explosion. As packaging for some applications include a large number of cells, the risk of failure is likely to be magnified. To address concerns about the safety of battery powered products, safety standards have been developed. This paper provides a review of various international safety standards specific to lithium-ion cells. This paper shows that though the standards are harmonized on a host of abuse conditions, most lack a test simulating internal short circuits. This paper describes some efforts to introduce internal short circuit tests into safety standards.

  17. QUANTITATIVE STANDARDS FOR AUDIOVISUAL PERSONNEL, EQUIPMENT AND MATERIALS (IN ELEMENTARY, SECONDARY, AND HIGHER EDUCATION).

    ERIC Educational Resources Information Center

    COBUN, TED; AND OTHERS

    THIS DOCUMENT IS A STAGE IN A STUDY TO FORMULATE QUANTITATIVE GUIDELINES FOR THE AUDIO-VISUAL COMMUNICATIONS FIELD, BEING CONDUCTED BY DOCTORS GENE FARIS AND MENDEL SHERMAN UNDER A NATIONAL DEFENSE EDUCATION ACT CONTRACT. THE STANDARDS LISTED HERE HAVE BEEN OFFICIALLY APPROVED AND ADOPTED BY SEVERAL AGENCIES, INCLUDING THE DEPARTMENT OF…

  18. Teacher Empathy and Its Relationship to the Standardized Test Scores of Diverse Secondary English Students

    ERIC Educational Resources Information Center

    Bostic, Timothy B.

    2014-01-01

    The purpose of this research study was to ascertain whether there is a relationship between teachers' cognitive role taking aspect of empathy and the Virginia Standards of Learning (VSOL), English/Reading scores of their students. A correlational research design using hierarchical multiple regression was used to look for this relationship. In…

  19. Exploitation of secondary standard for calibration in units of Dw,1 cm and assessment of several HDR brachytherapy planning systems

    NASA Astrophysics Data System (ADS)

    Gabris, Frantisek; Zeman, Jozef; Valenta, Jiri; Selbach, Hans-Joachim

    2012-10-01

    A secondary standard of the BEV, calibrated at the PTB in terms of Dw,1 cm, was used for calibration of the well-type chamber-based measuring systems used in clinics. In addition to the calibration, we tried to employ it for assessment of treatment planning systems (TPS) used for each particular afterloader. The dose to water at 1 cm distance from the source position was calculated by the TPS, using reference data from the source producer certificate. The values were compared directly with the dose measured at the same distance from the source. The comparison has been carried out for GammaMed Plus and MicroSelectron HDR sources. Differences of secondary standard measurements and TPS calculations were lower than ±5%, which is below the achievable uncertainty of both dose measurement and dose determination by the TPS. Nevertheless, it is higher than generally accepted in the case of external beam radiotherapy. Additional direct measurements in terms of Dw,1 cm may improve the safety and reliability of patient treatment. Part of the EMRP JRP T02.J06 Project ‘Increasing Cancer Treatment Efficacy Using 3D Brachytherapy’.

  20. Radionuclide cystogram

    MedlinePlus

    ... the bladder. There is a small amount of radiation exposure with any nuclear scan (it comes from the radioisotope, not the scanner). The exposure is less than with standard x-rays. The radiation is very mild. Nearly all the radiation is ...

  1. Critical review and rethinking of USEPA secondary standards for maintaining organoleptic quality of drinking water.

    PubMed

    Dietrich, Andrea M; Burlingame, Gary A

    2015-01-20

    Consumers assess their tap water primarily by its taste, odor, and appearance. Starting in 1979, USEPA promulgated Secondary Maximum Contaminant Levels (SMCLs) as guidance for contaminants with organoleptic effects and also to maintain consumers’ confidence in tap water. This review assesses the basis for the 15 SMCLs (aluminum, chloride, color, copper, corrosivity, fluoride, foaming agents, iron, manganese, odor, pH, silver, sulfate, total dissolved solids, zinc) and summarizes advances in scientific knowledge since their promulgation. SMCLs for aluminum, color, pH, silver, sulfate, total dissolved solids, and zinc are appropriate at current values and remain consistent with sensory science literature. Recent advances in sensory and health sciences indicate that SMCLs for chloride, copper, fluoride, iron, and manganese are too high to minimize organoleptic effects. The SMCLs for corrosivity and foaming agents may be outdated. The SMCL for odor requires rethinking as the test does not correlate with consumer complaints. Since current stresses on source and treated waters include chemical spills, algal blooms, and increased salinization, organoleptic episodes that negatively impact consumer confidence and perception of tap water still occur and may increase. Thus, adherence to SMCLs can help maintain production of palatable water along with consumers’ confidence in their water providers. PMID:25517292

  2. Critical review and rethinking of USEPA secondary standards for maintaining organoleptic quality of drinking water.

    PubMed

    Dietrich, Andrea M; Burlingame, Gary A

    2015-01-20

    Consumers assess their tap water primarily by its taste, odor, and appearance. Starting in 1979, USEPA promulgated Secondary Maximum Contaminant Levels (SMCLs) as guidance for contaminants with organoleptic effects and also to maintain consumers’ confidence in tap water. This review assesses the basis for the 15 SMCLs (aluminum, chloride, color, copper, corrosivity, fluoride, foaming agents, iron, manganese, odor, pH, silver, sulfate, total dissolved solids, zinc) and summarizes advances in scientific knowledge since their promulgation. SMCLs for aluminum, color, pH, silver, sulfate, total dissolved solids, and zinc are appropriate at current values and remain consistent with sensory science literature. Recent advances in sensory and health sciences indicate that SMCLs for chloride, copper, fluoride, iron, and manganese are too high to minimize organoleptic effects. The SMCLs for corrosivity and foaming agents may be outdated. The SMCL for odor requires rethinking as the test does not correlate with consumer complaints. Since current stresses on source and treated waters include chemical spills, algal blooms, and increased salinization, organoleptic episodes that negatively impact consumer confidence and perception of tap water still occur and may increase. Thus, adherence to SMCLs can help maintain production of palatable water along with consumers’ confidence in their water providers.

  3. Building a robust, scalable and standards-driven infrastructure for secondary use of EHR data: The SHARPn project

    PubMed Central

    Rea, Susan; Pathak, Jyotishman; Savova, Guergana; Oniki, Thomas A.; Westberg, Les; Beebe, Calvin E.; Tao, Cui; Parker, Craig G.; Haug, Peter J.; Huff, Stanley M.; Chute, Christopher G.

    2016-01-01

    The Strategic Health IT Advanced Research Projects (SHARP) Program, established by the Office of the National Coordinator for Health Information Technology in 2010 supports research findings that remove barriers for increased adoption of health IT. The improvements envisioned by the SHARP Area 4 Consortium (SHARPn) will enable the use of the electronic health record (EHR) for secondary purposes, such as care process and outcomes improvement, biomedical research and epidemiologic monitoring of the nation’s health. One of the primary informatics problem areas in this endeavor is the standardization of disparate health data from the nation’s many health care organizations and providers. The SHARPn team is developing open source services and components to support the ubiquitous exchange, sharing and reuse or ‘liquidity’ of operational clinical data stored in electronic health records. One year into the design and development of the SHARPn framework, we demonstrated end to end data flow and a prototype SHARPn platform, using thousands of patient electronic records sourced from two large healthcare organizations: Mayo Clinic and Intermountain Healthcare. The platform was deployed to (1) receive source EHR data in several formats, (2) generate structured data from EHR narrative text, and (3) normalize the EHR data using common detailed clinical models and Consolidated Health Informatics standard terminologies, which were (4) accessed by a phenotyping service using normalized data specifications. The architecture of this prototype SHARPn platform is presented. The EHR data throughput demonstration showed success in normalizing native EHR data, both structured and narrative, from two independent organizations and EHR systems. Based on the demonstration, observed challenges for standardization of EHR data for interoperable secondary use are discussed. PMID:22326800

  4. Gallbladder radionuclide scan

    MedlinePlus

    Radionuclide - gallbladder; Gallbladder scan; Biliary scan; Cholescintigraphy: HIDA; Hepatobiliary nuclear imaging scan ... small amount of morphine. This can help the radionuclide get into the gallbladder. The morphine may cause ...

  5. Natural radionuclide mobility and its influence on U-Th-Pb dating of secondary minerals from the unsaturated zone at Yucca Mountain, Nevada

    USGS Publications Warehouse

    Neymark, L.A.; Amelin, Y.V.

    2008-01-01

    Extreme U and Pb isotope variations produced by disequilibrium in decay chains of 238U and 232Th are found in calcite, opal/chalcedony, and Mn-oxides occurring as secondary mineral coatings in the unsaturated zone at Yucca Mountain, Nevada. These very slowly growing minerals (mm my-1) contain excess 206Pb and 208Pb formed from excesses of intermediate daughter isotopes and cannot be used as reliable 206Pb/238U geochronometers. The presence of excess intermediate daughter isotopes does not appreciably affect 207Pb/235U ages of U-enriched opal/chalcedony, which are interpreted as mineral formation ages. Opal and calcite from outer (younger) portions of coatings have 230Th/U ages from 94.6 ?? 3.7 to 361.3 ?? 9.8 ka and initial 234U/238U activity ratios (AR) from 4.351 ?? 0.070 to 7.02 ?? 0.12, which indicate 234U enrichment from percolating water. Present-day 234U/238U AR is ???1 in opal/chalcedony from older portions of the coatings. The 207Pb/235U ages of opal/chalcedony samples range from 0.1329 ?? 0.0080 to 9.10 ?? 0.21 Ma, increase with microstratigraphic depth, and define slow long-term average growth rates of about 1.2-2.0 mm my-1, in good agreement with previous results. Measured 234U/238U AR in Mn-oxides, which pre-date the oldest calcite and opal/chalcedony, range from 0.939 ?? 0.006 to 2.091 ?? 0.006 and are >1 in most samples. The range of 87Sr/86Sr ratios (0.71156-0.71280) in Mn-oxides overlaps that in the late calcite. These data indicate that Mn-oxides exchange U and Sr with percolating water and cannot be used as a reliable dating tool. In the U-poor calcite samples, measured 206Pb/207Pb ratios have a wide range, do not correlate with Ba concentration as would be expected if excess Ra was present, and reach a value of about 1400, the highest ever reported for natural Pb. Calcite intergrown with opal contains excesses of both 206Pb and 207Pb derived from Rn diffusion and from direct ??-recoil from U-rich opal. Calcite from coatings devoid of opal

  6. Source geometry factors for HDR ¹⁹²Ir brachytherapy secondary standard well-type ionization chamber calibrations.

    PubMed

    Shipley, D R; Sander, T; Nutbrown, R F

    2015-03-21

    Well-type ionization chambers are used for measuring the source strength of radioactive brachytherapy sources before clinical use. Initially, the well chambers are calibrated against a suitable national standard. For high dose rate (HDR) (192)Ir, this calibration is usually a two-step process. Firstly, the calibration source is traceably calibrated against an air kerma primary standard in terms of either reference air kerma rate or air kerma strength. The calibrated (192)Ir source is then used to calibrate the secondary standard well-type ionization chamber. Calibration laboratories are usually only equipped with one type of HDR (192)Ir source. If the clinical source type is different from that used for the calibration of the well chamber at the standards laboratory, a source geometry factor, k(sg), is required to correct the calibration coefficient for any change of the well chamber response due to geometric differences between the sources. In this work we present source geometry factors for six different HDR (192)Ir brachytherapy sources which have been determined using Monte Carlo techniques for a specific ionization chamber, the Standard Imaging HDR 1000 Plus well chamber with a type 70010 HDR iridium source holder. The calculated correction factors were normalized to the old and new type of calibration source used at the National Physical Laboratory. With the old Nucletron microSelectron-v1 (classic) HDR (192)Ir calibration source, ksg was found to be in the range 0.983 to 0.999 and with the new Isodose Control HDR (192)Ir Flexisource k(sg) was found to be in the range 0.987 to 1.004 with a relative uncertainty of 0.4% (k = 2). Source geometry factors for different combinations of calibration sources, clinical sources, well chambers and associated source holders, can be calculated with the formalism discussed in this paper.

  7. Targeted radionuclide therapy

    SciTech Connect

    Williams, Lawrence E.; DeNardo, Gerald L.; Meredith, Ruby F.

    2008-07-15

    Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake, in percent-injected dose per gram of malignant tissue, is used to evaluate the specificity of the targeting vehicle. Lymphoma (B-cell) has been the primary clinical application. Extension to solid tumors will require raising the macroscopic absorbed dose by several-fold over values found in present technology. Methods that may effect such changes include multistep targeting, simultaneous chemotherapy, and external sequestration of the agent. Toxicity has primarily involved red marrow so that marrow replacement can also be used to enhance future TRT treatments. Correlation of toxicities and treatment efficiency has been limited by relatively poor absorbed dose estimates partly because of using standard (phantom) organ sizes. These associations will be improved in the future by obtaining patient-specific organ size and activity data with hybrid SPECT/CT and PET/CT scanners.

  8. Targeted radionuclide therapy

    PubMed Central

    Williams, Lawrence E.; DeNardo, Gerald L.; Meredith, Ruby F.

    2008-01-01

    Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake, in percent-injected dose per gram of malignant tissue, is used to evaluate the specificity of the targeting vehicle. Lymphoma (B-cell) has been the primary clinical application. Extension to solid tumors will require raising the macroscopic absorbed dose by several-fold over values found in present technology. Methods that may effect such changes include multistep targeting, simultaneous chemotherapy, and external sequestration of the agent. Toxicity has primarily involved red marrow so that marrow replacement can also be used to enhance future TRT treatments. Correlation of toxicities and treatment efficiency has been limited by relatively poor absorbed dose estimates partly because of using standard (phantom) organ sizes. These associations will be improved in the future by obtaining patient-specific organ size and activity data with hybrid SPECT∕CT and PET∕CT scanners. PMID:18697529

  9. Role of Concentration and Time of Day in Developing Ozone Exposure Indices for a Secondary Standard.

    PubMed

    Lee, E H; Hogsett, W E

    1999-06-01

    Evidence from exposure-response studies and a turbulent transfer model demonstrate that plant response is differential to concentration, duration, temporal pattern, and time of day of exposure. Reductions in productivity of crops and trees as seedlings are greater when plants are exposed to higher daytime ozone (O3) concentrations (0800-2000 hr standard time) or for longer durations. Primary evidence on the greater role of concentration comes from exposure-response experiments where plants are exposed to a series of pollutant concentrations in open-top chambers under field conditions. These studies demonstrate that the integrated exposure indices that give preferential weight to higher concentrations are better predictors of response than mean or peak indices. Evidence suggesting that mid-range O3 concentrations (0.05-0.09 parts per million, ppm) play a greater role than higher concentrations (>0.09 ppm) in biological response could not be justified. The time of day when O3 concentrations and atmospheric and stomatal conductances of gas exchange are optimal is a key to understanding plant response because plants respond only to O3 entering the leaf via stomata. A turbulent transfer model that describes the resistance of pollutant gas exchange from the atmosphere to the boundary layer of a forest canopy, as a function of micrometeorological variables, is developed to determine when flux of O3 is optimal. Based on meteorological and ambient air quality monitoring data at remote forest sites in the United States, it appears that O3 flux densities to the forest boundary layer are optimal during the 0800-2000 hr window. It is concluded that descriptors of ambient air quality for use in setting a federal standard should (1) cumulate hourly O3 concentrations, (2) give preferential weight to daytime concentrations between 0800 and 2000 hr, and (3) give preferential weight to higher O3 concentrations.

  10. RADIONUCLIDE INVENTORY AND DISTRIBUTION: FOURMILE BRANCH, PEN BRANCH, AND STEEL CREEK IOUS

    SciTech Connect

    Hiergesell, R.; Phifer, M.

    2014-04-29

    As a condition to the Department of Energy (DOE) Low Level Waste Disposal Federal Facility Review Group (LFRG) review team approving the Savannah River Site (SRS) Composite Analysis (CA), SRS agreed to follow up on a secondary issue, which consisted of the consolidation of several observations that the team concluded, when evaluated collectively, could potentially impact the integration of the CA results. This report addresses secondary issue observations 4 and 21, which identify the need to improve the CA sensitivity and uncertainty analysis specifically by improving the CA inventory and the estimate of its uncertainty. The purpose of the work described herein was to be responsive to these secondary issue observations by re-examining the radionuclide inventories of the Integrator Operable Units (IOUs), as documented in ERD 2001 and Hiergesell, et. al. 2008. The LFRG concern has been partially addressed already for the Lower Three Runs (LTR) IOU (Hiergesell and Phifer, 2012). The work described in this investigation is a continuation of the effort to address the LFRG concerns by re-examining the radionuclide inventories associated with Fourmile Branch (FMB) IOU, Pen Branch (PB) IOU and Steel Creek (SC) IOU. The overall approach to computing radionuclide inventories for each of the IOUs involved the following components: • Defining contaminated reaches of sediments along the IOU waterways • Identifying separate segments within each IOU waterway to evaluate individually • Computing the volume and mass of contaminated soil associated with each segment, or “compartment” • Obtaining the available and appropriate Sediment and Sediment/Soil analytical results associated with each IOU • Standardizing all radionuclide activity by decay-correcting all sample analytical results from sample date to the current point in time, • Computing representative concentrations for all radionuclides associated with each compartment in each of the IOUs • Computing the

  11. Radionuclide deposition control

    DOEpatents

    Brehm, William F.; McGuire, Joseph C.

    1980-01-01

    The deposition of radionuclides manganese-54, cobalt-58 and cobalt-60 from liquid sodium coolant is controlled by providing surfaces of nickel or high nickel alloys to extract the radionuclides from the liquid sodium, and by providing surfaces of tungsten, molybdenum or tantalum to prevent or retard radionuclide deposition.

  12. PVDF reference hydrophone development in the UK-from fabrication and lamination to use as secondary standards.

    PubMed

    Robinson, S; Preston, R; Smith, M; Millar, C

    2000-01-01

    During the last 30 yrs, PVDF has been used extensively as a sensor material. Over this period, the GEC-Marconi Research Centre has developed a wide range of devices based on PVDF as a piezoelectric transducer material. The ability to create laminated structures has led to an enhancement in performance and has allowed innovative designs to be realized. This paper describes the development of the laminated PVDF structure and its benefits, such as increased sensitivity and improved signal to noise ratio. Examples of devices utilizing the lamination process are given in the form of both a bilaminar-shielded membrane hydrophone and a PVDF sonar hydrophone. Performance properties of both types of hydrophones are presented along with a discussion of their use as secondary standard hydrophones at the National Physical Laboratory (NPL).

  13. 2009 LANL radionuclide air emissions report

    SciTech Connect

    Fuehne, David P.

    2010-06-01

    The emissions of radionuclides from Department of Energy Facilities such as Los Alamos National Laboratory (LANL) are regulated by the Amendments to the Clean Air Act of 1990, National Emissions Standards for Hazardous Air Pollutants (40 CFR 61 Subpart H). These regulations established an annual dose limit of 10 mrem to the maximally exposed member of the public attributable to emissions of radionuclides. This document describes the emissions of radionuclides from LANL and the dose calculations resulting from these emissions for calendar year 2009. This report meets the reporting requirements established in the regulations.

  14. 2008 LANL radionuclide air emissions report

    SciTech Connect

    Fuehne, David P.

    2009-06-01

    The emissions of radionuclides from Department of Energy Facilities such as Los Alamos National Laboratory (LANL) are regulated by the Amendments to the Clean Air Act of 1990, National Emissions Standards for Hazardous Air Pollutants (40 CFR 61 Subpart H). These regulations established an annual dose limit of 10 mrem to the maximally exposed member of the public attributable to emissions of radionuclides. This document describes the emissions of radionuclides from LANL and the dose calculations resulting from these emissions for calendar year 2008. This report meets the reporting requirements established in the regulations.

  15. 2010 LANL radionuclide air emissions report /

    SciTech Connect

    Fuehne, David P.

    2011-06-01

    The emissions of radionuclides from Department of Energy Facilities such as Los Alamos National Laboratory (LANL) are regulated by the Amendments to the Clean Air Act of 1990, National Emissions Standards for Hazardous Air Pollutants (40 CFR 61 Subpart H). These regulations established an annual dose limit of 10 mrem to the maximally exposed member of the public attributable to emissions of radionuclides. This document describes the emissions of radionuclides from LANL and the dose calculations resulting from these emissions for calendar year 2010. This report meets the reporting requirements established in the regulations.

  16. Possible secondary apatite fission track age standard from altered volcanic ash beds in the middle Jurassic Carmel Formation, Southwestern Utah

    USGS Publications Warehouse

    Kowallis, B.J.; Christiansen, E.H.; Everett, B.H.; Crowley, K.D.; Naeser, C.W.; Miller, D.S.; Deino, A.L.

    1993-01-01

    Secondary age standards are valuable in intra- and interlaboratory calibration. At present very few such standards are available for fission track dating that is older than Tertiary. Several altered volcanic ash beds occur in the Middle Jurassic Carmel Formation in southwestern Utah. The formation was deposited in a shallow marine/sabhka environment. Near Gunlock, Utah, eight ash beds have been identified. Sanidines from one of the ash beds (GUN-F) give a single-crystal laser-probe 40Ar/39Ar age of 166.3??0.8 Ma (2??). Apatite and zircon fission track ages range from 152-185 Ma with typically 15-20 Ma errors (2??). Track densities in zircons are high and most grains are not countable. Apatites are fairly common in most of the ash beds and have reasonable track densities ranging between 1.2-1.5 ?? 106 tracks/cm2. Track length distributions in apatites are unimodal, have standard deviations <1??m, and mean track lengths of about 14-14.5 ??m. High Cl apatites (F:Cl:OH ratio of 39:33:28) are particularly abundant and large in ash GUN-F, and are fairly easy to concentrate, but the concentrates contain some siderite, most of which can be removed by sieving. GUN-F shows evidence of some reworking and detriaal contamination based on older single grain 40Ar/39Ar analyses and some rounding of grains, but the apatite population appears to be largely uncontaminated. At present BJK has approximately 12 of apatite separate from GUN-F. ?? 1993.

  17. Acute gangrenous cholecystitis: radionuclide diagnosis

    SciTech Connect

    Brachman, M.B.; Tanasescu, D.E.; Ramanna, L.; Waxman, A.D.

    1984-04-01

    Radionuclide hepatobiliary imaging with Tc-99m IDA is a useful procedure for the diagnosis of acute cholecystitis. Visualization of the gallbladder essentially rules out acute cholecystitis. Nonvisualization suggest acute cholecystitis but may also be associated with chronic gallbladder disease or other conditions. The authors recently observed five patients in whom a rim of increased parenchymal liver activity was seen adjacent to the gallbladder fossa. All five patients had acute gangrenous cholecystitis. The rim of increased activity appears to be a useful secondary sign of acute cholecystitis.

  18. Quantitative radionuclide angiocardiography

    SciTech Connect

    Scholz, P.M.; Rerych, S.K.; Moran, J.F.; Newman, G.E.; Douglas, J.M.; Sabiston, D.C. Jr.; Jones, R.H.

    1980-01-01

    This study introduces a new method for calculating actual left ventricular volumes and cardiac output from data recorded during a single transit of a radionuclide bolus through the heart, and describes in detail current radionuclide angiocardiography methodology. A group of 64 healthy adults with a wide age range were studied to define the normal range of hemodynamic parameters determined by the technique. Radionuclide angiocardiograms were performed in patients undergoing cardiac catherization to validate the measurements. In 33 patients studied by both techniques on the same day, a close correlation was documented for measurement of ejection fraction and end-diastolic volume. To validate the method of volumetric cardiac output calcuation, 33 simultaneous radionuclide and indocyanine green dye determinations of cardiac output were performed in 18 normal young adults. These independent comparisons of radionuclide measurements with two separate methods document that initial transit radionuclide angiocardiography accurately assesses left ventricular function.

  19. Common Pressures, Same Results? Recent Reforms in Professional Standards and Competences in Teacher Education for Secondary Teachers in England, France and Germany

    ERIC Educational Resources Information Center

    Page, Tina M.

    2015-01-01

    Over the last decade, the introduction of professional standards and competences in initial teacher education for secondary teachers in England, France and Germany has provided the cornerstone of education reform in all three countries. The precise number and specific content of a measurable set of skills for teachers have offered challenges for…

  20. 40 CFR Appendix H to Part 50 - Interpretation of the 1-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... waiver of the ozone monitoring requirement would be handled under provisions of 40 CFR, part 58. Some... year unless the appropriate Regional Administrator has granted a waiver under the provisions of 40 CFR... and Secondary National Ambient Air Quality Standards for Ozone H Appendix H to Part 50 Protection...

  1. 40 CFR Appendix H to Part 50 - Interpretation of the 1-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... waiver of the ozone monitoring requirement would be handled under provisions of 40 CFR, part 58. Some... year unless the appropriate Regional Administrator has granted a waiver under the provisions of 40 CFR... and Secondary National Ambient Air Quality Standards for Ozone H Appendix H to Part 50 Protection...

  2. 40 CFR Appendix H to Part 50 - Interpretation of the 1-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... waiver of the ozone monitoring requirement would be handled under provisions of 40 CFR, part 58. Some... year unless the appropriate Regional Administrator has granted a waiver under the provisions of 40 CFR... and Secondary National Ambient Air Quality Standards for Ozone H Appendix H to Part 50 Protection...

  3. Student Achievement Standards and Testing. Testimony before the Subcommittee on Elementary, Secondary, and Vocational Education of the Committee on Education and Labor, House of Representatives.

    ERIC Educational Resources Information Center

    Chelimsky, Eleanor

    The General Accounting Office (GAO), at the request of the House Committee on Education and Labor, Subcommittee on Elementary, Secondary, and Vocational Education, conducted studies on the extent and cost of testing in the United States, the experience of Canada in testing, and initial efforts to set standards for judging student performance on…

  4. 40 CFR Appendix H to Part 50 - Interpretation of the 1-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... waiver of the ozone monitoring requirement would be handled under provisions of 40 CFR, part 58. Some... year unless the appropriate Regional Administrator has granted a waiver under the provisions of 40 CFR... and Secondary National Ambient Air Quality Standards for Ozone H Appendix H to Part 50 Protection...

  5. Photon doses in NPL standard neutron fields.

    PubMed

    Roberts, N J; Horwood, N A; McKay, C J

    2014-10-01

    Standard neutron fields are invariably accompanied by a photon component due to the neutron-generating reactions and secondary neutron interactions in the surrounding environment. A set of energy-compensated Geiger-Müller (GM) tubes and electronic personal dosemeters (EPDs) have been used to measure the photon dose rates in a number of standard radionuclide and accelerator-based neutron fields. The GM tubes were first characterised in standard radioisotope and X-ray photon fields and then modelled using MCNP to determine their photon dose response as a function of energy. Values for the photon-to-neutron dose equivalent ratios are presented and compared with other published values.

  6. SECONDARY STANDARD CALIBRATION, MEASUREMENT AND IRRADIATION CAPABILITIES OF THE INDIVIDUAL MONITORING SERVICE AT THE HELMHOLTZ ZENTRUM MÜNCHEN: ASPECTS OF UNCERTAINTY AND AUTOMATION.

    PubMed

    Greiter, M B; Denk, J; Hoedlmoser, H

    2016-09-01

    The individual monitoring service at the Helmholtz Zentrum München has adopted the recommendations of the ISO 4037 and 6980 standards series as base of its dosimetric systems for X-ray, gamma and beta dosimetry. These standards define technical requirements for radiation spectra and measurement processes, but leave flexibility in the implementation of irradiations as well as in the resulting uncertainty in dose or dose rate. This article provides an example for their practical implementation in the Munich IAEA/WHO secondary standard dosimetry laboratory. It focusses on two aspects: automation issues and uncertainties in calibration. PMID:26838065

  7. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... identification of non-hazardous secondary materials that are solid wastes when used as fuels or ingredients in...) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion...

  8. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... identification of non-hazardous secondary materials that are solid wastes when used as fuels or ingredients in...) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion...

  9. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... identification of non-hazardous secondary materials that are solid wastes when used as fuels or ingredients in...) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion...

  10. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... identification of non-hazardous secondary materials that are solid wastes when used as fuels or ingredients in...) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion...

  11. The Status of Special Education Teachers at the Secondary Level: Effects of the "Highly Qualified Teacher" Standard

    ERIC Educational Resources Information Center

    Quigney, Theresa A.

    2009-01-01

    This article highlights issues that secondary special education teachers are facing as a result of the legally mandated "highly qualified teacher" (HQT) requirement. The valid demand for teachers to document core subject area competency is often compounded for secondary special education teachers by the requirement to teach multiple core areas.…

  12. Radionuclide behavior in the environment

    SciTech Connect

    Tveten, U. )

    1991-09-01

    The purpose of this report is to document the results of the following task: Review for quality and consistency the available data on measurements of initial ground contamination of Chernobyl radionuclides in various parts of Norway and subsequent concentrations of these radionuclides in various environmental media as functions of time. Utilize the data obtained to verify the existing models, or to improve them, for describing radionuclide behavior in the environment. Some of the processes standard were: migration into soil; weathering; resuspension; food-chain contamination; and loss or reconcentration by run-off. The task performed within this contract has been to use post-Chernobyl data from Norway to verify or find areas for possible improvement in the chronic exposure pathway models utilized in MACCS. Work has consisted mainly of collecting and evaluating post-Chernobyl information from Norway or other countries when relevant; but has also included experimental work performed specifically for the current task. In most connections the data available show the models and data in MACCS to be appropriate. A few areas where the data indicate that the MACCS approach is faulty or inadequate are, however, pointed out in the report. These should be examined carefully, and appropriate modifications should eventually be made. 14 refs., 12 figs., 22 tabs.

  13. VALIDATION OF ANSI N42.34 AMERICAN NATIONAL STANDARD PERFORMANCE CRITERIA FOR HAND-HELD INSTRUMENTS FOR THE DETECTION AND IDENTIFICATION OF RADIONUCLIDES

    SciTech Connect

    Lorier, T.

    2014-09-03

    SRNL’s validation of ANSI N42.34-D6 for the Domestic Nuclear Detection Office (DNDO) was performed utilizing one hand-held instrument (or RID) – the FLIR identiFINDER 2. Each section of the standard was evaluated via a walk-through or test. NOTE: In Table 1, W = walk-through and T = test, as directed by the Domestic Nuclear Detection Office (DNDO). For a walk-through, the experiment was either setup or reviewed for setup; for a test, the N42.34-D6 procedures were followed with some exceptions and comments noted. SRNL is not fully able to evaluate a RID against Sections 7 (Environmental), 8 (Electromagnetic), and 9 (Mechanical) of N42.34, so those portions of this validation were done in collaboration with Qualtest, Inc. in Orlando, Florida. The walk-throughs and tests of Sections 7, 8, and 9 were performed in Qualtest, Inc. facilities with SRNL providing radiological sources as necessary. Where applicable, assessment results and findings of the walk-throughs and tests were recorded on datasheets and a validation summary is provided. A general comment pertained to test requirements found in another standard and referenced in N42.34-D6. For example, step 1 of the test method in section 8.1.2 states “RF test set up information can be found in IEC 61000-4-3.” It is recommended that any information from other standards necessary for conducting the tests within N42.34 should be posted in N42.34 for simplicity and to prevent the user from having to peruse other documents. Another general comment, as noted by Qualtest, is that a tolerance reference is not listed for each test in sections 7-9. Overall, the N42.34-D6 was proven to be practicable, but areas for improvement and recommendations were identified for consideration prior to final ballot submittal.

  14. Radionuclides in US coals

    SciTech Connect

    Bisselle, C. A.; Brown, R. D.

    1984-03-01

    The current state of knowledge with respect to radionuclide concentrations in US coals is discussed. Emphasis is placed on the levels of uranium in coal (and lignite) which are considered to represent a concern resulting from coal combustion; areas of the US where such levels have been found; and possible origins of high radionuclide levels in coal. The report reviews relevant studies and presents new data derived from a computerized search of radionuclide content in about 4000 coal samples collected throughout the coterminous US. 103 references, 5 figures, 5 tables.

  15. The Next Generation Science Standards, Common Core State Standards, and English Learners: Using the SSTELLA Framework to Prepare Secondary Science Teachers

    ERIC Educational Resources Information Center

    Tolbert, Sara; Stoddart, Trish; Lyon, Edward G.; Solis, Jorge

    2014-01-01

    This article focuses on a critical issue in STEM education: preparing novice secondary school teachers to provide effective science instruction to the rapidly growing population of students from language minority groups who traditionally have been underserved in STEM education and who are underrepresented in STEM degrees and careers (National…

  16. Radionuclide Behavior in Containments.

    2000-02-14

    MATADOR analyzes the transport and deposition of radionuclides as vapor or aerosol through Light Water Reactor (LWR) containments during severe accidents and calculates environmental release fractions of radionuclides as a function of time. It is intended for use in system risk studies. The principal output is information on the timing and magnitude of radionuclide releases to the environment as a result of severely degraded core accidents. MATADOR considers the transport of radionuclides through the containmentmore » and their removal by natural deposition and the operation of engineered safety systems such as sprays. Input data on the source term from the primary system, the containment geometry, and thermal-hydraulic conditions are required.« less

  17. Radionuclides in Diagnosis.

    ERIC Educational Resources Information Center

    Williams, E. D.

    1989-01-01

    Discussed is a radionuclide imaging technique, including the gamma camera, image analysis computer, radiopharmaceuticals, and positron emission tomography. Several pictures showing the use of this technique are presented. (YP)

  18. 40 CFR 50.11 - National primary and secondary ambient air quality standards for oxides of nitrogen (with...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... air quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). 50.11 Section... quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). (a) The level of the national primary annual ambient air quality standard for oxides of nitrogen is 53 parts per billion...

  19. 40 CFR 50.11 - National primary and secondary ambient air quality standards for oxides of nitrogen (with...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... air quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). 50.11 Section... quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). (a) The level of the national primary annual ambient air quality standard for oxides of nitrogen is 53 parts per billion...

  20. 40 CFR 50.11 - National primary and secondary ambient air quality standards for oxides of nitrogen (with...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... air quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). 50.11 Section... quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). (a) The level of the national primary annual ambient air quality standard for oxides of nitrogen is 53 parts per billion...

  1. 40 CFR 50.11 - National primary and secondary ambient air quality standards for oxides of nitrogen (with...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... air quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). 50.11 Section... quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). (a) The level of the national primary annual ambient air quality standard for oxides of nitrogen is 53 parts per billion...

  2. 40 CFR 50.11 - National primary and secondary ambient air quality standards for oxides of nitrogen (with...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... air quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). 50.11 Section... quality standards for oxides of nitrogen (with nitrogen dioxide as the indicator). (a) The level of the national primary annual ambient air quality standard for oxides of nitrogen is 53 parts per billion...

  3. 75 FR 61486 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... Standards for Oxides of Nitrogen and Oxides of Sulfur: Second External Review Draft (75 FR 57463, September..., framing of key issues and conclusions regarding options for key elements of the standards. The four... (summary of options for elements of the nitrogen oxides (NO X ) and sulfur oxides (SO X ) standard)....

  4. Method and apparatus for separating radionuclides from non-radionuclides

    DOEpatents

    Harp, Richard J.

    1990-01-01

    In an apparatus for separating radionuclides from non-radionuclides in a mixture of nuclear waste, a vessel is provided wherein the mixture is heated to a temperature greater than the temperature of vaporization for the non-radionuclides but less than the temperature of vaporization for the radionuclides. Consequently the non-radionuclides are vaporized while the non-radionuclides remain the solid or liquid state. The non-radionuclide vapors are withdrawn from the vessel and condensed to produce a flow of condensate. When this flow decreases the heat is reduced to prevent temperature spikes which might otherwise vaporize the radionuclides. The vessel is removed and capped with the radioactive components of the apparatus and multiple batches of the radionuclide residue disposed therein. Thus the vessel ultimately provides a burial vehicle for all of the radioactive components of the process.

  5. Data Authentication Demonstration for Radionuclide Stations

    SciTech Connect

    Harris, Mark; Herrington, Pres; Miley, Harry; Ellis, J. Edward; McKinnon, David; St. Pierre, Devon

    1999-08-03

    Data authentication is required for certification of sensor stations in the International Monitoring System (IMS). Authentication capability has been previously demonstrated for continuous waveform stations (seismic and infrasound). This paper addresses data surety for the radionuclide stations in the IMS, in particular the Radionuclide Aerosol Sampler/Analyzer (RASA) system developed by Pacific Northwest National Laboratory (PNNL). Radionuclide stations communicate data by electronic mail using formats defined in IMS 1.0, Formats and Protocols for Messages. An open message authentication standard exists, called S/MIME (Secure/Multipurpose Internet Mail Extensions), which has been proposed for use with all IMS radionuclide station message communications. This standard specifies adding a digital signature and public key certificate as a MIME attachment to the e-mail message. It is advantageous because it allows authentication to be added to all IMS 1.0 messages in a standard format and is commercially supported in e-mail software. For command and control, the RASA system uses a networked Graphical User Interface (GUI) based upon Common Object Request Broker Architecture (CORBA) communications, which requires special authentication procedures. The authors have modified the RASA system to meet CTBTO authentication guidelines, using a FORTEZZA card for authentication functions. They demonstrated signing radionuclide data messages at the RASA, then sending, receiving, and verifying the messages at a data center. They demonstrated authenticating command messages and responses from the data center GUI to the RASA. Also, the particular authentication system command to change the private/public key pair and retrieve the new public key was demonstrated. This work shows that data surety meeting IMS guidelines may be immediately applied to IMS radionuclide systems.

  6. A Randomized Trial Comparing the Efficacy and Safety of Intravitreal Triamcinolone With Standard Care to Treat Vision Loss Associated With Macular Edema Secondary to Branch Retinal Vein Occlusion

    PubMed Central

    Scott, Ingrid U.; Ip, Michael S.; VanVeldhuisen, Paul C.; Oden, Neal L.; Blodi, Barbara A.; Fisher, Marian; Chan, Clement K.; Gonzalez, Victor H.; Singerman, Lawrence J.; Tolentino, Michael

    2009-01-01

    Objective: To compare the efficacy and safety of 1-mg and 4-mg doses of preservative-free intravitreal triamcinolone with standard care (grid photocoagulation in eyes without dense macular hemorrhage and deferral of photocoagulation until hemorrhage clears in eyes with dense macular hemorrhage) for eyes with vision loss associated with macular edema secondary to branch retinal vein occlusion (BRVO). Methods: Multicenter, randomized clinical trial of 411 participants. Main Outcome Measure: Gain in visual acuity letter score of 15 or more from baseline to month 12. Results: Twenty-nine percent, 26%, and 27% of participants achieved the primary outcome in the standard care, 1-mg, and 4-mg groups, respectively. None of the pairwise comparisons between the 3 groups was statistically significant at month 12. The rates of elevated intraocular pressure and cataract were similar for the standard care and 1-mg groups, but higher in the 4-mg group. Conclusions: There was no difference identified in visual acuity at 12 months for the standard care group compared with the triamcinolone groups; however, rates of adverse events (particularly elevated intraocular pressure and cataract) were highest in the 4-mg group. Application to Clinical Practice: Grid photocoagulation as applied in the SCORE Study remains the standard care for patients with vision loss associated with macular edema secondary to BRVO who have characteristics similar to participants in the SCORE-BRVO trial. Grid photocoagulation should remain the benchmark against which other treatments are compared in clinical trials for eyes with vision loss associated with macular edema secondary to BRVO. Trial Registration: clinicaltrials.gov Identifier: NCT00105027 PMID:19752420

  7. Detection of subdural empyema with radionuclides

    SciTech Connect

    McKillop, J.H.; Holtzman, D.S.; McDougall, I.R.

    1980-06-01

    Computed tomography (CT) is now the standard method of confirming a diagnosis of suspected subdural empyema. We report a case in which the radionuclide brain scan was abnormal at a time when the CT scan was normal. An /sup 111/In-labeled leukocyte scan was also performed in this patient and demonstrated abnormal uptake in the empyema. The scintigraphic findings in a second case of subdural empyema are also described. The relative roles of radionuclide studies and CT scans in the patient with suspected subdural empyema are discussed.

  8. 2014 LANL Radionuclide Air Emissions Report

    SciTech Connect

    Fuehne, David Patrick

    2015-07-21

    This report describes the emissions of airborne radionuclides from operations at Los Alamos National Laboratory (LANL) for calendar year 2014, and the resulting off-site dose from these emissions. This document fulfills the requirements established by the National Emissions Standards for Hazardous Air Pollutants in 40 CFR 61, Subpart H – Emissions of Radionuclides other than Radon from Department of Energy Facilities, commonly referred to as the Radionuclide NESHAP or Rad-NESHAP. Compliance with this regulation and preparation of this document is the responsibility of LANL’s RadNESHAP compliance program, which is part of the Environmental Protection Division. The information in this report is required under the Clean Air Act and is being submitted to the U.S. Environmental Protection Agency (EPA) Region 6.

  9. Initial Radionuclide Inventories

    SciTech Connect

    Miller, H

    2005-07-12

    The purpose of this analysis is to provide an initial radionuclide inventory (in grams per waste package) and associated uncertainty distributions for use in the Total System Performance Assessment for the License Application (TSPA-LA) in support of the license application for the repository at Yucca Mountain, Nevada. This document is intended for use in postclosure analysis only. Bounding waste stream information and data were collected that capture probable limits. For commercially generated waste, this analysis considers alternative waste stream projections to bound the characteristics of wastes likely to be encountered using arrival scenarios that potentially impact the commercial spent nuclear fuel (CSNF) waste stream. For TSPA-LA, this radionuclide inventory analysis considers U.S. Department of Energy (DOE) high-level radioactive waste (DHLW) glass and two types of spent nuclear fuel (SNF): CSNF and DOE-owned (DSNF). These wastes are placed in two groups of waste packages: the CSNF waste package and the codisposal waste package (CDSP), which are designated to contain DHLW glass and DSNF, or DHLW glass only. The radionuclide inventory for naval SNF is provided separately in the classified ''Naval Nuclear Propulsion Program Technical Support Document'' for the License Application. As noted previously, the radionuclide inventory data presented here is intended only for TSPA-LA postclosure calculations. It is not applicable to preclosure safety calculations. Safe storage, transportation, and ultimate disposal of these wastes require safety analyses to support the design and licensing of repository equipment and facilities. These analyses will require radionuclide inventories to represent the radioactive source term that must be accommodated during handling, storage and disposition of these wastes. This analysis uses the best available information to identify the radionuclide inventory that is expected at the last year of last emplacement, currently identified as

  10. Initial Radionuclide Inventories

    SciTech Connect

    H. Miller

    2004-09-19

    The purpose of this analysis is to provide an initial radionuclide inventory (in grams per waste package) and associated uncertainty distributions for use in the Total System Performance Assessment for the License Application (TSPA-LA) in support of the license application for the repository at Yucca Mountain, Nevada. This document is intended for use in postclosure analysis only. Bounding waste stream information and data were collected that capture probable limits. For commercially generated waste, this analysis considers alternative waste stream projections to bound the characteristics of wastes likely to be encountered using arrival scenarios that potentially impact the commercial spent nuclear fuel (CSNF) waste stream. For TSPA-LA, this radionuclide inventory analysis considers U.S. Department of Energy (DOE) high-level radioactive waste (DHLW) glass and two types of spent nuclear fuel (SNF): CSNF and DOE-owned (DSNF). These wastes are placed in two groups of waste packages: the CSNF waste package and the codisposal waste package (CDSP), which are designated to contain DHLW glass and DSNF, or DHLW glass only. The radionuclide inventory for naval SNF is provided separately in the classified ''Naval Nuclear Propulsion Program Technical Support Document'' for the License Application. As noted previously, the radionuclide inventory data presented here is intended only for TSPA-LA postclosure calculations. It is not applicable to preclosure safety calculations. Safe storage, transportation, and ultimate disposal of these wastes require safety analyses to support the design and licensing of repository equipment and facilities. These analyses will require radionuclide inventories to represent the radioactive source term that must be accommodated during handling, storage and disposition of these wastes. This analysis uses the best available information to identify the radionuclide inventory that is expected at the last year of last emplacement, currently identified as

  11. Radionuclide studies in impotence

    SciTech Connect

    Hilson, A.J.; Lewis, C.A. )

    1991-04-01

    Impotence may be of physiological origin with causes including vascular or neurological pathology. Alternatively, it may be of psychogenic origin. Clinicians can distinguish between psychological and organic impotence by observing nocturnal penile tumescence. Non-radionuclide investigations for organic impotence include penile plethysmography or pulse Doppler analysis for arterial supply, cavernosometry for venous drainage, and biothesiometry or evoked potentials for neurological pathology. Radionuclide studies are primarily based on the use of technetium 99m-pertechnetate, 99mTc-red blood cells, or xenon 133 to study the blood flow, with or without pharmacological intervention, commonly papaverine. 26 references.

  12. Bioinformatics in the secondary science classroom: A study of state content standards and students' perceptions of, and performance in, bioinformatics lessons

    NASA Astrophysics Data System (ADS)

    Wefer, Stephen H.

    The proliferation of bioinformatics in modern Biology marks a new revolution in science, which promises to influence science education at all levels. This thesis examined state standards for content that articulated bioinformatics, and explored secondary students' affective and cognitive perceptions of, and performance in, a bioinformatics mini-unit. The results are presented as three studies. The first study analyzed secondary science standards of 49 U.S States (Iowa has no science framework) and the District of Columbia for content related to bioinformatics at the introductory high school biology level. The bionformatics content of each state's Biology standards were categorized into nine areas and the prevalence of each area documented. The nine areas were: The Human Genome Project, Forensics, Evolution, Classification, Nucleotide Variations, Medicine, Computer Use, Agriculture/Food Technology, and Science Technology and Society/Socioscientific Issues (STS/SSI). Findings indicated a generally low representation of bioinformatics related content, which varied substantially across the different areas. Recommendations are made for reworking existing standards to incorporate bioinformatics and to facilitate the goal of promoting science literacy in this emerging new field among secondary school students. The second study examined thirty-two students' affective responses to, and content mastery of, a two-week bioinformatics mini-unit. The findings indicate that the students generally were positive relative to their interest level, the usefulness of the lessons, the difficulty level of the lessons, likeliness to engage in additional bioinformatics, and were overall successful on the assessments. A discussion of the results and significance is followed by suggestions for future research and implementation for transferability. The third study presents a case study of individual differences among ten secondary school students, whose cognitive and affective percepts were

  13. Secondary analysis of anthropometric data from a South African national food consumption survey, using different growth reference standards.

    PubMed

    Bosman, L; Herselman, M G; Kruger, H S; Labadarios, D

    2011-11-01

    The National Center for Health Statistics (NCHS) references were used to analyse anthropometric data from the 1999 National Food Consumption Survey (NFCS) of South Africa. Since then, however, The Centers for Disease Control and Prevention (CDC) 2000 reference and the World Health Organization (WHO) 2006 standards were released. It was anticipated that these reference and standards may lead to differences in the previous estimates of stunting, wasting, underweight and obesity in the study population. The aim was to compare the anthropometric status of children using the 1977 NCHS, the 2000 CDC growth references and the 2006 WHO standards. All children 12-60 months of age with a complete set of anthropometric data were included in the analyses. Data for 1,512 children were analysed with SAS 9.1 for Windows. A Z-score was calculated for each child for weight-for-age (W/A), weight-for-length/height (W/H), length/height-for-age (H/A) and body mass index (BMI)-for-age, using each of the three reference or standards for comparison. The prevalence of stunting, obesity and overweight were significantly higher and the prevalence of underweight and wasting were lower when using the WHO standards compared to the NCHS and the CDC references. The higher than previously established prevalence of stunting at 20.1% and combined overweight/obesity at 30% poses a challenge to South African policy makers to implement nutrition programmes to decrease the prevalence of both stunting and overweight. The 2006 WHO growth standard should be the standard used for assessment of growth of infants and children younger than 5 years in developing countries.

  14. Radionuclide bone scanning in giant cell tumor

    SciTech Connect

    Van Nostrand, D.; Madewell, J.E.; McNiesh, L.M.; Kyle, R.W.; Sweet, D.

    1986-03-01

    Radionuclide bone scan findings are described and correlated with pathology in 23 patients with giant cell tumor (GCT) of the bone. The degree of radionuclide activity was markedly increased in 20 (87%), minimally increased in three (13%), and decreased in none of the patients. Of the 23 patients with increased radioactivity, the pattern was diffuse in 11 (48%) and doughnut in 12 (52%). Extended patterns of radioactivity were present in 19 of 22 patients; however, none were associated with true tumor extension. Bone scanning did not aid in the detection of GCT, was nonspecific, and did not differentiate benign from malignant GCT. Although radioactivity extended beyond the radiographic abnormality in the majority of patients, this was most likely secondary to other bony abnormalities or local and/or regional hyperemia, and caution should be taken in ascribing this extension to either tumor or metastasis.

  15. 76 FR 59599 - Extension of Comment Period for Secondary National Ambient Air Quality Standards for Oxides of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ..., 2011, (76 FR 46084) and is available on the following Web site: http://www.epa.gov/ttn/naaqs/standards/no2so2sec/cr_fr.html . How can I get copies of this document and other related information? The EPA has... Federal Register on August 1, 2011, (76 FR 46084) for detailed information on accessing...

  16. Preservice Secondary Teachers' Conceptions from a Mathematical Modeling Activity and Connections to the Common Core State Standards

    ERIC Educational Resources Information Center

    Stohlmann, Micah; Maiorca, Cathrine; Olson, Travis A.

    2015-01-01

    Mathematical modeling is an essential integrated piece of the Common Core State Standards. However, researchers have shown that mathematical modeling activities can be difficult for teachers to implement. Teachers are more likely to implement mathematical modeling activities if they have their own successful experiences with such activities. This…

  17. An Examination of Intervention Research with Secondary Students with EBD in Light of Common Core State Standards for Mathematics

    ERIC Educational Resources Information Center

    Mulcahy, Candace A.; Maccini, Paula; Wright, Kenneth; Miller, Jason

    2014-01-01

    In this review, the authors offer a critical analysis of published interventions for improving mathematics performance among middle and high school students with EBD in light of the Common Core State Standards. An exhaustive review of literature from 1975 to December 2012 yielded 20 articles that met criteria for inclusion. The authors analyzed…

  18. The Impact of Curriculum Changes and Implementation of Secondary Mathematics Georgia Performance Standards on Teacher Self-Efficacy

    ERIC Educational Resources Information Center

    Ramsey, John Phillip

    2012-01-01

    Teachers generally experience a decline in self-efficacy levels during a curriculum change, and Georgia converted from a Quality Core Curriculum (QCC) to Georgia Performance Standards (GPS) the last several years. Middle and high school math teachers experienced an annual tiered rollout of the mathematics curriculum, and this qualitative study was…

  19. 76 FR 48073 - Public Hearing for Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... airport security procedures. After passing through the equipment, all persons must sign in at the guard... the notice of proposed rulemaking published in the Federal Register on August 1, 2011, (76 FR 46084....epa.gov/ttn/naaqs/standards/no2so2sec/cr_fr.html . FOR FURTHER INFORMATION CONTACT: If you would...

  20. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J. Prouty

    2006-07-14

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport

  1. Proficiency Testing as a tool to monitor consistency of measurements in the IAEA/WHO Network of Secondary Standards Dosimetry Laboratories

    NASA Astrophysics Data System (ADS)

    Meghzifene, Ahmed; Czap, Ladislav; Shortt, Ken

    2008-08-01

    The International Atomic Energy Agency (IAEA) and the World Health Organization (WHO) established a Network of Secondary Standards Dosimetry Laboratories (IAEA/WHO SSDL Network) in 1976. Through SSDLs designated by Member States, the Network provides a direct link of national dosimetry standards to the international measurement system of standards traceable to the Bureau International des Poids et Mesures (BIPM). Within this structure and through the proper calibration of field instruments, the SSDLs disseminate S.I. quantities and units. To ensure that the services provided by SSDL members to end-users follow internationally accepted standards, the IAEA has set up two different comparison programmes. One programme relies on the IAEA/WHO postal TLD service and the other uses comparisons of calibrated ionization chambers to help the SSDLs verify the integrity of their national standards and the procedures used for the transfer of the standards to the end-users. The IAEA comparisons include 60Co air kerma (NK) and absorbed dose to water (ND,W) coefficients. The results of the comparisons are confidential and are communicated only to the participants. This is to encourage participation of the laboratories and their full cooperation in the reconciliation of any discrepancy. This work describes the results of the IAEA programme comparing calibration coefficients for radiotherapy dosimetry, using ionization chambers. In this programme, ionization chambers that belong to the SSDLs are calibrated sequentially at the SSDL, at the IAEA, and again at the SSDL. As part of its own quality assurance programme, the IAEA has participated in several regional comparisons organized by Regional Metrology Organizations. The results of the IAEA comparison programme show that the majority of SSDLs are capable of providing calibrations that fall inside the acceptance level of 1.5% compared to the IAEA.

  2. Proficiency Testing as a tool to monitor consistency of measurements in the IAEA/WHO Network of Secondary Standards Dosimetry Laboratories

    SciTech Connect

    Meghzifene, Ahmed; Czap, Ladislav; Shortt, Ken

    2008-08-14

    The International Atomic Energy Agency (IAEA) and the World Health Organization (WHO) established a Network of Secondary Standards Dosimetry Laboratories (IAEA/WHO SSDL Network) in 1976. Through SSDLs designated by Member States, the Network provides a direct link of national dosimetry standards to the international measurement system of standards traceable to the Bureau International des Poids et Mesures (BIPM). Within this structure and through the proper calibration of field instruments, the SSDLs disseminate S.I. quantities and units.To ensure that the services provided by SSDL members to end-users follow internationally accepted standards, the IAEA has set up two different comparison programmes. One programme relies on the IAEA/WHO postal TLD service and the other uses comparisons of calibrated ionization chambers to help the SSDLs verify the integrity of their national standards and the procedures used for the transfer of the standards to the end-users. The IAEA comparisons include {sup 60}Co air kerma (N{sub K}) and absorbed dose to water (N{sub D,W}) coefficients. The results of the comparisons are confidential and are communicated only to the participants. This is to encourage participation of the laboratories and their full cooperation in the reconciliation of any discrepancy.This work describes the results of the IAEA programme comparing calibration coefficients for radiotherapy dosimetry, using ionization chambers. In this programme, ionization chambers that belong to the SSDLs are calibrated sequentially at the SSDL, at the IAEA, and again at the SSDL. As part of its own quality assurance programme, the IAEA has participated in several regional comparisons organized by Regional Metrology Organizations.The results of the IAEA comparison programme show that the majority of SSDLs are capable of providing calibrations that fall inside the acceptance level of 1.5% compared to the IAEA.

  3. Radionuclide bone imaging

    SciTech Connect

    Bassett, L.W.; Gold, R.H.; Webber, M.M.

    1981-12-01

    Radionuclide bone imaging of the skeleton, now well established as the most important diagnostic procedure in detecting bone metastases, is also a reliable method for the evaluation of the progression or regression of metastatic bone disease. The article concentrates on the technetium-99m agents and the value of these agents in the widespread application of low-dose radioisotope scanning in such bone diseases as metastasis, osteomyelitis, trauma, osteonecrosis, and other abnormal skeletal conditions.

  4. 40 CFR 61.92 - Standard.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standard. 61.92 Section 61.92... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standards for Emissions of Radionuclides Other Than Radon From Department of Energy Facilities § 61.92 Standard. Emissions of radionuclides...

  5. Illicit Trafficking of Natural Radionuclides

    SciTech Connect

    Friedrich, Steinhaeusler; Lyudmila, Zaitseva

    2008-08-07

    Natural radionuclides have been subject to trafficking worldwide, involving natural uranium ore (U 238), processed uranium (yellow cake), low enriched uranium (<20% U 235) or highly enriched uranium (>20% U 235), radium (Ra 226), polonium (Po 210), and natural thorium ore (Th 232). An important prerequisite to successful illicit trafficking activities is access to a suitable logistical infrastructure enabling an undercover shipment of radioactive materials and, in case of trafficking natural uranium or thorium ore, capable of transporting large volumes of material. Covert en route diversion of an authorised uranium transport, together with covert diversion of uranium concentrate from an operating or closed uranium mines or mills, are subject of case studies. Such cases, involving Israel, Iran, Pakistan and Libya, have been analyzed in terms of international actors involved and methods deployed. Using international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (DSTO) and international experience gained from the fight against drug trafficking, a generic Trafficking Pathway Model (TPM) is developed for trafficking of natural radionuclides. The TPM covers the complete trafficking cycle, ranging from material diversion, covert material transport, material concealment, and all associated operational procedures. The model subdivides the trafficking cycle into five phases: (1) Material diversion by insider(s) or initiation by outsider(s); (2) Covert transport; (3) Material brokerage; (4) Material sale; (5) Material delivery. An Action Plan is recommended, addressing the strengthening of the national infrastructure for material protection and accounting, development of higher standards of good governance, and needs for improving the control system deployed by customs, border guards and security forces.

  6. Illicit Trafficking of Natural Radionuclides

    NASA Astrophysics Data System (ADS)

    Friedrich, Steinhäusler; Lyudmila, Zaitseva

    2008-08-01

    Natural radionuclides have been subject to trafficking worldwide, involving natural uranium ore (U 238), processed uranium (yellow cake), low enriched uranium (<20% U 235) or highly enriched uranium (>20% U 235), radium (Ra 226), polonium (Po 210), and natural thorium ore (Th 232). An important prerequisite to successful illicit trafficking activities is access to a suitable logistical infrastructure enabling an undercover shipment of radioactive materials and, in case of trafficking natural uranium or thorium ore, capable of transporting large volumes of material. Covert en route diversion of an authorised uranium transport, together with covert diversion of uranium concentrate from an operating or closed uranium mines or mills, are subject of case studies. Such cases, involving Israel, Iran, Pakistan and Libya, have been analyzed in terms of international actors involved and methods deployed. Using international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (DSTO) and international experience gained from the fight against drug trafficking, a generic Trafficking Pathway Model (TPM) is developed for trafficking of natural radionuclides. The TPM covers the complete trafficking cycle, ranging from material diversion, covert material transport, material concealment, and all associated operational procedures. The model subdivides the trafficking cycle into five phases: (1) Material diversion by insider(s) or initiation by outsider(s); (2) Covert transport; (3) Material brokerage; (4) Material sale; (5) Material delivery. An Action Plan is recommended, addressing the strengthening of the national infrastructure for material protection and accounting, development of higher standards of good governance, and needs for improving the control system deployed by customs, border guards and security forces.

  7. 2006 LANL Radionuclide Air Emissions Report

    SciTech Connect

    David P. Fuehne

    2007-06-30

    This report describes the impacts from emissions of radionuclides at Los Alamos National Laboratory (LANL) for calendar year 2006. This report fulfills the requirements established by the Radionuclide National Emissions Standards for Hazardous Air Pollutants (Rad-NESHAP). This report is prepared by LANL's Rad-NESHAP compliance team, part of the Environmental Protection Division. The information in this report is required under the Clean Air Act and is being reported to the U.S. Environmental Protection Agency (EPA). The highest effective dose equivalent (EDE) to an off-site member of the public was calculated using procedures specified by the EPA and described in this report. LANL's EDE was 0.47 mrem for 2006. The annual limit established by the EPA is 10 mrem per year. During calendar year 2006, LANL continuously monitored radionuclide emissions at 28 release points, or stacks. The Laboratory estimates emissions from an additional 58 release points using radionuclide usage source terms. Also, LANL uses a network of air samplers around the Laboratory perimeter to monitor ambient airborne levels of radionuclides. To provide data for dispersion modeling and dose assessment, LANL maintains and operates meteorological monitoring systems. From these measurement systems, a comprehensive evaluation is conducted to calculate the EDE for the Laboratory. The EDE is evaluated as any member of the public at any off-site location where there is a residence, school, business, or office. In 2006, this location was the Los Alamos Airport Terminal. The majority of this dose is due to ambient air sampling of plutonium emitted from 2006 clean-up activities at an environmental restoration site (73-002-99; ash pile). Doses reported to the EPA for the past 10 years are shown in Table E1.

  8. Methods for determining radionuclide retardation factors: status report

    SciTech Connect

    Relyea, J.F.; Serne, R.J.; Rai, D.

    1980-04-01

    This report identifies a number of mechanisms that retard radionuclide migration, and describes the static and dynamic methods that are used to study such retardation phenomena. Both static and dynamic methods are needed for reliable safety assessments of underground nuclear-waste repositories. This report also evaluates the extent to which the two methods may be used to diagnose radionuclide migration through various types of geologic media, among them unconsolidated, crushed, intact, and fractured rocks. Adsorption is one mechanism that can control radionuclide concentrations in solution and therefore impede radionuclide migration. Other mechanisms that control a solution's radionuclide concentration and radionuclide migration are precipitation of hydroxides and oxides, oxidation-reduction reactions, and the formation of minerals that might include the radionuclide as a structural element. The retardation mechanisms mentioned above are controlled by such factors as surface area, cation exchange capacity, solution pH, chemical composition of the rock and of the solution, oxidation-reduction potential, and radionuclide concentration. Rocks and ground waters used in determining retardation factors should represent the expected equilibrium conditions in the geologic system under investigation. Static test methods can be used to rapidly screen the effects of the factors mentioned above. Dynamic (or column) testing, is needed to assess the effects of hydrodynamics and the interaction of hydrodynamics with the other important parameters. This paper proposes both a standard method for conducting batch Kd determinations, and a standard format for organizing and reporting data. Dynamic testing methods are not presently developed to the point that a standard methodology can be proposed. Normal procedures are outlined for column experimentation and the data that are needed to analyze a column experiment are identified.

  9. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J.D. Schreiber

    2005-08-25

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers

  10. Investigating the impact of course-taking on the standardized test performance of secondary science students in Texas

    NASA Astrophysics Data System (ADS)

    Bailey, Bryan Scott

    2007-12-01

    The latest reform efforts in American education have called for the improvement of science education and greater accountability for results. Standardization of schools, curriculum, and testing has emerged as the preferred method of addressing the increasing pressures of accountability systems designed to ensure student achievement. Increasing course-taking requirements has been a popular response intended to maximize student potential. Texas, like other states, has pursued that course. Texas students must take a minimum of two science courses to graduate; most, however, take three. Students must also pass a science assessment in the eleventh grade, which is similar to a test taken in the tenth grade, and measures mastery of objectives covered primarily in the ninth- and tenth-grades, meaning the instruction most students receive in the eleventh grade amounts to enrichment instruction. This study was designed to investigate the impact of completing an extra science course on student achievement in terms of improvement on these tests. The results of the study were derived from descriptive analysis and a one-way ANOVA performed on a random sample of over 16,000 students. Based on the ANOVA, there was a significant effect of increased science instruction on mean pre-test/post-test score change (F(2,16530) = 44.903, p=.000). The descriptive analysis concluded that more students who completed a science class increased their scores than those who did not complete a class. Overall, however, the study points to a need for future research to uncover additional factors that influence student achievement.

  11. Radionuclide Sensors for Water Monitoring

    SciTech Connect

    Grate, Jay W.; Egorov, Oleg B.; DeVol, Timothy A.

    2005-09-01

    Radionuclide contamination in the soil and groundwater at U.S. Department of Energy (DOE) sites is a severe problem that requires monitoring and remediation. Radionuclide measurement techniques are needed to monitor surface waters, groundwater, and process waters. Typically, water samples are collected and transported to an analytical laboratory, where costly radiochemical analyses are performed. To date, there has been very little development of selective radionuclide sensors for alpha- and beta-emitting radionuclides such as 90Sr, 99Tc, and various actinides of interest.

  12. History of medical radionuclide production.

    PubMed

    Ice, R D

    1995-11-01

    Radionuclide production for medical use originally was incidental to isotope discoveries by physicists and chemists. Once the available radionuclides were identified they were evaluated for potential medical use. Hevesy first used 32P in 1935 to study phosphorous metabolism in rats. Since that time, the development of cyclotrons, linear accelerators, and nuclear reactors have produced hundreds of radionuclides for potential medical use. The history of medical radionuclide production represents an evolutionary, interdisciplinary development of applied nuclear technology. Today the technology is represented by a mature industry and provides medical benefits to millions of patients annually.

  13. Osteopetrosis: radiological & radionuclide imaging.

    PubMed

    Sit, Cherry; Agrawal, Kanhaiyalal; Fogelman, Ignac; Gnanasegaran, Gopinath

    2015-01-01

    Osteopetrosis is a rare inherited bone disease where bones harden and become abnormally dense. While the diagnosis is clinical, it also greatly relies on appearance of the skeleton radiographically. X-ray, radionuclide bone scintigraphy and magnetic resonance imaging have been reported to identify characteristics of osteopetrosis. We present an interesting case of a 59-year-old man with a history of bilateral hip fractures. He underwent (99m)Tc-methylene diphosphonate whole body scan supplemented with single-photon emission computed tomography/computed tomography of spine, which showed increased uptake in the humeri, tibiae and femora, which were in keeping with osteopetrosis.

  14. Evaluation of radionuclide dose-calibrator measurements

    SciTech Connect

    Paras, P.; Comer, F.M.; Demeis, F.; Coursey, B.M.; Calhoun, J.M.; Golas, D.B.

    1986-01-01

    Performance data for radionuclide dose calibrators, which are primarily ionization chambers, are scarce. Large deviations have occasionally been reported, particularly for low photon energies, i.e., emissions from /sup 201/Tl, /sup 133/Xe. The volunteer user program (QB series) of the College of American Pathologists (CAP) (laboratory intercomparison quality control), supported by the US National Bureau of Standards (NBS), for quality control of dose calibrators was suspended. The Atomic Industrial Forum (AIF) has a quality control program among radiopharmaceutical manufacturers but there is no user program in the US at this time, and the performance of dose calibrators in the field is not known. In addition, a number of professionals expressed a strong feeling for the continuation of the CAP program and the availability of standards for dose calibrators from NBS. The objective of this study is twofold: (a) to evaluate the accuracy of dose calibrator measurements for individual patient radioactivity administered doses, and (b) to provide certified sources of certain radionuclides to calibrate the instruments for these radionuclides.

  15. Reactor-Produced Medical Radionuclides

    SciTech Connect

    Mirzadeh, Saed; Mausner, Leonard; Garland, Marc A

    2011-01-01

    The therapeutic use of radionuclides in nuclear medicine, oncology and cardiology is the most rapidly growing use of medical radionuclides. Since most therapeutic radionuclides are neutron rich and decay by beta emission, they are reactor-produced. This chapter deals mainly with production approaches with neutrons. Neutron interactions with matter, neutron transmission and activation rates, and neutron spectra of nuclear reactors are discussed in some detail. Further, a short discussion of the neutron-energy dependence of cross sections, reaction rates in thermal reactors, cross section measurements and flux monitoring, and general equations governing the reactor production of radionuclides are presented. Finally, the chapter is concluded by providing a number of examples encompassing the various possible reaction routes for production of a number of medical radionuclides in a reactor.

  16. APT radionuclide production experiment

    SciTech Connect

    Ullmann, J.L.; Gavron, A.; King, J.D.

    1994-07-02

    Tritium ({sup 3}H, a heavy isotope of hydrogen) is produced by low energy neutron-induced reactions on various elements. One such reaction is n+{sup 3}He {yields}>{sup 3}H+{sup 1}H in which {sup 3}He is transmuted to tritium. Another reaction, which has been used in reactor production of tritium, is the n+{sup 6}Li {yields}> {sup 3}H+{sup 4}He reaction. Accelerator Production of Tritium relies on a high-energy proton beam to produce these neutrons using the spallation reaction, in which high-energy proton beam to produce these neutrons using the spallation reaction, in which high-energy protons reacting with a heavy nucleus produce a shower of low-energy neutrons and a lower-mass residual nucleus. It is important to quantify the residual radionuclides produced in the spallation target for two reasons. From an engineering point of view, one must understand short-lived isotopes that may contribute to decay heat. From a safety viewpoint, one must understand what nuclei and decay gammas are produced in order to design adequate shielding, to estimate ultimate waste disposal problems, and to predict possible effects due to accidental dispersion during operation. The authors have performed an experiment to measure the production of radioisotopes in stopping-length W and Pb targets irradiated by a 800 MeV proton beam, and are comparing the results to values obtained from calculations using LAHET and MCNP. The experiment was designed to pay particular attention to the short half-life radionuclides, which have not been previously measured. In the following, they present details of the experiment, explain how they analyzed the data and obtain the results, how they perform the calculations, and finally, how the experimental data agree with the calculations.

  17. Radionuclide Air Emission Report for 2009

    SciTech Connect

    Wahl, Linnea

    2010-06-01

    Berkeley Lab operates facilities where radionuclides are handled and stored. These facilities are subject to the EPA radioactive air emission regulations in 40CFR61, Subpart H (EPA 1989). Radionuclides may be emitted from stacks or vents on buildings where radionuclide production or use is authorized or they may be emitted as diffuse sources. In 2009, all Berkeley Lab sources were minor sources of radionuclides (sources resulting in a potential dose of less than 0.1 mrem/yr [0.001 mSv/yr]). These minor sources included more than 100 stack sources and one source of diffuse emissions. There were no unplanned emissions from the Berkeley Lab site. Emissions from minor sources (stacks and diffuse emissions) either were measured by sampling or monitoring or were calculated based on quantities used, received for use, or produced during the year. Using measured and calculated emissions, and building-specific and common parameters, Laboratory personnel applied the EPA-approved computer code, CAP88-PC, to calculate the effective dose equivalent to the maximally exposed individual (MEI). The effective dose equivalent from all sources at Berkeley Lab in 2009 is 7.0 x 10{sup -3} mrem/yr (7.0 x 10{sup -5} mSv/yr) to the MEI, well below the 10 mrem/yr (0.1 mSv/yr) dose standard. The location of the MEI is at the University of California (UC) Lawrence Hall of Science, a public science museum about 1500 ft (460 m) east of Berkeley Lab's Building 56. The estimated collective effective dose equivalent to persons living within 50 mi (80 km) of Berkeley Lab is 1.5 x 10{sup -1} person-rem (1.5 x 10{sup -3} person-Sv) attributable to the Lab's airborne emissions in 2009.

  18. Radionuclide Air Emission Report for 2008

    SciTech Connect

    Wahl, Linnea

    2009-05-21

    Berkeley Lab operates facilities where radionuclides are handled and stored. These facilities are subject to the U.S. Environmental Protection Agency (EPA) radioactive air emission regulations in Code of Federal Regulations (CFR) Title 40, Part 61, Subpart H (EPA 1989). Radionuclides may be emitted from stacks or vents on buildings where radionuclide production or use is authorized or they may be emitted as diffuse sources. In 2008, all Berkeley Lab sources were minor sources of radionuclides (sources resulting in a potential dose of less than 0.1 mrem/yr [0.001 mSv/yr]). These minor sources include more than 100 stack sources and one source of diffuse emissions. There were no unplanned emissions from the Berkeley Lab site. Emissions from minor sources (stacks and diffuse emissions) either were measured by sampling or monitoring or were calculated based on quantities used, received for use, or produced during the year. Using measured and calculated emissions, and building-specific and common parameters, Laboratory personnel applied the EPA-approved computer code, CAP88-PC, to calculate the effective dose equivalent to the maximally exposed individual (MEI). The effective dose equivalent from all sources at Berkeley Lab in 2008 is 5.2 x 10{sup -3} mrem/yr (5.2 x 10{sup -5} mSv/yr) to the MEI, well below the 10 mrem/yr (0.1 mSv/yr) dose standard. The location of the MEI is at the University of California (UC) Lawrence Hall of Science, a public science museum about 1500 ft (460 m) east of Berkeley Lab's Building 56. The estimated collective effective dose equivalent to persons living within 50 mi (80 km) of Berkeley Lab is 1.1 x 10{sup -1} person-rem (1.1 x 10{sup -3} person-Sv) attributable to the Lab's airborne emissions in 2008.

  19. Radionuclide Air Emission Report for 2007

    SciTech Connect

    Wahl, Linnea; Wahl, Linnea

    2008-06-13

    Berkeley Lab operates facilities where radionuclides are handled and stored. These facilities are subject to the U.S. Environmental Protection Agency (EPA) radioactive air emission regulations in Code of Federal Regulations (CFR) Title 40, Part 61, Subpart H (EPA 1989). The EPA regulates radionuclide emissions that may be released from stacks or vents on buildings where radionuclide production or use is authorized or that may be emitted as diffuse sources. In 2007, all Berkeley Lab sources were minor stack or building emissions sources of radionuclides (sources resulting in a potential dose of less than 0.1 mrem/yr [0.001 mSv/yr]), there were no diffuse emissions, and there were no unplanned emissions. Emissions from minor sources either were measured by sampling or monitoring or were calculated based on quantities received for use or produced during the year. Using measured and calculated emissions, and building-specific and common parameters, Laboratory personnel applied the EPA-approved computer code, CAP88-PC, Version 3.0, to calculate the effective dose equivalent to the maximally exposed individual (MEI). The effective dose equivalent from all sources at Berkeley Lab in 2007 is 1.2 x 10{sup -2} mrem/yr (1.2 x 10{sup -4} mSv/yr) to the MEI, well below the 10 mrem/yr (0.1 mSv/yr) EPA dose standard. The location of the MEI is at the University of California (UC) Lawrence Hall of Science, a public science museum about 1500 ft (460 m) east of Berkeley Lab's Building 56. The estimated collective effective dose equivalent to persons living within 50 mi (80 km) of Berkeley Lab is 3.1 x 10{sup -1} person-rem (3.1 x 10{sup -3} person-Sv) attributable to the Lab's airborne emissions in 2007.

  20. (Depth-dose curves of the beta reference fields (147)Pm, (85)Kr and (90)Sr/(90)Y produced by the beta secondary standard BSS2.

    PubMed

    Brunzendorf, Jens

    2012-08-01

    The most common reference fields in beta dosimetry are the ISO 6980 series 1 radiation fields produced by the beta secondary standard BSS2 and its predecessor BSS. These reference fields require sealed beta radiation sources ((147)Pm, (85)Kr or (90)Sr/(90)Y) in combination with a source-specific beam-flattening filter, and are defined only at a given distance from the source. Every radiation sources shipped with the BSS2 is sold with a calibration certificate of the Physikalisch-Technische Bundesanstalt. The calibration workflow also comprises regular depth-dose measurements. This work publishes complete depth-dose curves of the series 1 sources (147)Pm, (85)Kr and (90)Sr/(90)Y in ICRU tissue up to a depth of 11 mm,when all electrons are stopped. For this purpose, the individual depth-dose curves of all BSS2 sources calibrated so far have been determined, i.e. the complete datasets of all BSS2 beta sources have been re-evaluated. It includes 191 depth-dose curves of 116 different sources comprising more than 2200 data points in total. Appropriate analytical representations of the nuclide-specific depth-dose curves are provided for the first time.

  1. Radionuclide therapy for arthritic knees

    SciTech Connect

    Doepel, L.K.

    1985-02-08

    A new radionuclide therapeutic approach for rheumatoid arthritis of the knee is described. This therapy combines a short-lived radionuclide with a carrier whose physical and chemical characteristics aid retention of the radioactive particles within the joint. Joining a radionuclide to a particulate carrier had not been explored previously as a potential method for inhibiting radiation leakage. The treatment couples the rare earth element dysprosium 165 to ferric hydroxide in macroaggregate form (size range: 3 to 10 ..mu..m). After the relatively inert iron complex penetrates the synovium, it causes cell death. Macrophages and phagocytes clear away the cellular debris, essentially eliminating the synovium.

  2. Radionuclide Retention in Concrete Wasteforms

    SciTech Connect

    Bovaird, Chase C.; Jansik, Danielle P.; Wellman, Dawn M.; Wood, Marcus I.

    2011-09-30

    Assessing long-term performance of Category 3 waste cement grouts for radionuclide encasement requires knowledge of the radionuclide-cement interactions and mechanisms of retention (i.e., sorption or precipitation); the mechanism of contaminant release; the significance of contaminant release pathways; how wasteform performance is affected by the full range of environmental conditions within the disposal facility; the process of wasteform aging under conditions that are representative of processes occurring in response to changing environmental conditions within the disposal facility; the effect of wasteform aging on chemical, physical, and radiological properties; and the associated impact on contaminant release. This knowledge will enable accurate prediction of radionuclide fate when the wasteforms come in contact with groundwater. The information present in the report provides data that (1) measures the effect of concrete wasteform properties likely to influence radionuclide migration; and (2) quantifies the rate of carbonation of concrete materials in a simulated vadose zone repository.

  3. Drift-Scale Radionuclide Transport

    SciTech Connect

    J. Houseworth

    2004-09-22

    The purpose of this model report is to document the drift scale radionuclide transport model, taking into account the effects of emplacement drifts on flow and transport in the vicinity of the drift, which are not captured in the mountain-scale unsaturated zone (UZ) flow and transport models ''UZ Flow Models and Submodels'' (BSC 2004 [DIRS 169861]), ''Radionuclide Transport Models Under Ambient Conditions'' (BSC 2004 [DIRS 164500]), and ''Particle Tracking Model and Abstraction of Transport Process'' (BSC 2004 [DIRS 170041]). The drift scale radionuclide transport model is intended to be used as an alternative model for comparison with the engineered barrier system (EBS) radionuclide transport model ''EBS Radionuclide Transport Abstraction'' (BSC 2004 [DIRS 169868]). For that purpose, two alternative models have been developed for drift-scale radionuclide transport. One of the alternative models is a dual continuum flow and transport model called the drift shadow model. The effects of variations in the flow field and fracture-matrix interaction in the vicinity of a waste emplacement drift are investigated through sensitivity studies using the drift shadow model (Houseworth et al. 2003 [DIRS 164394]). In this model, the flow is significantly perturbed (reduced) beneath the waste emplacement drifts. However, comparisons of transport in this perturbed flow field with transport in an unperturbed flow field show similar results if the transport is initiated in the rock matrix. This has led to a second alternative model, called the fracture-matrix partitioning model, that focuses on the partitioning of radionuclide transport between the fractures and matrix upon exiting the waste emplacement drift. The fracture-matrix partitioning model computes the partitioning, between fractures and matrix, of diffusive radionuclide transport from the invert (for drifts without seepage) into the rock water. The invert is the structure constructed in a drift to provide the floor of the

  4. Radionuclide salivary gland imaging

    SciTech Connect

    Mishkin, F.S.

    1981-10-01

    Salivary gland imaging with 99mTc as pertechnetate provides functional information concerning trapping and excretion of the parotid and submandibular glands. Anatomic information gained often adds little to clinical evaluation. On the other hand, functional information may detect subclinical involvement, which correlates well with biopsy of the minor labial salivary glands. Salivary gland abnormalities in systemic disease such as sarcoidosis, rheumatoid arthritis, lupus erythematosus, and other collagenvascular disorders may be detected before they result in the clinical manifestaions of Sjoegren's syndrome. Such glands, after initially demonstrating increased trapping in the acute phase, tend to have decreased trapping and failure to discharge pertechnetate in response to an appropriate physiologic stimulus. Increased uptake of gallium-67 citrate often accompanies these findings. Inflammatory parotitis can be suspected when increased perfusion is evident on radionuclide angiography with any agent. The ability of the salivary gland image to detect and categorize mass lesions, which result in focal areas of diminished activity such as tumors, cysts, and most other masses, is disappointing, while its ability to detect and categorize Warthin's tumor, which concentrates pertechnetate, is much more valuable, although not specific.

  5. Video instrumentation for radionuclide angiocardiography.

    NASA Technical Reports Server (NTRS)

    Kriss, J. P.

    1973-01-01

    Two types of videoscintiscopes for performing radioisotopic angiocardiography with a scintillation camera are described, and use of these instruments in performing clinical studies is illustrated. Radionuclide angiocardiography is a simple, quick and accurate procedure recommended as a screening test for patients with a variety of congenital and acquired cardiovascular lesions. When performed in conjunction with coronary arterial catheterization, dynamic radionuclide angiography may provide useful information about regional myocardial perfusion. Quantitative capabilities greatly enhance the potential of this diagnostic tool.

  6. Anthropogenic radionuclides in the environment

    SciTech Connect

    Hu, Q; Weng, J; Wang, J

    2007-11-15

    Studies of radionuclides in the environment have entered a new era with the renaissance of nuclear energy and associated fuel reprocessing, geological disposal of high-level nuclear wastes, and concerns about national security with respect to nuclear non-proliferation. This work presents an overview of anthropogenic radionuclide contamination in the environment, as well as the salient geochemical behavior of important radionuclides. We first discuss the following major anthropogenic sources and current development that contribute to the radionuclide contamination of the environment: (1) nuclear weapons program; (2) nuclear weapons testing; (3) nuclear power plants; (4) commercial fuel reprocessing; (5) geological repository of high-level nuclear wastes, and (6) nuclear accidents. Then, we summarize the geochemical behavior for radionuclides {sup 99}Tc, {sup 129}I, and {sup 237}Np, because of their complex geochemical behavior, long half-lives, and presumably high mobility in the environment. Biogeochemical cycling and environment risk assessment must take into account speciation of these redox-sensitive radionuclides.

  7. Radioimmunotherapy of malignancy using antibody targeted radionuclides.

    PubMed Central

    Cobb, L. M.; Humm, J. L.

    1986-01-01

    Antibodies directed against tumour associated antigens provide a means for delivering preferentially cytotoxic radionuclides to the cells of primary and secondary tumours. The factors that influence the effectiveness of the radiation in the tumour compared with its effect on the radiosensitive normal tissues include the specificity of the antibody, the distribution of targeted energy within the tumour and the host's response to the injected foreign antibody. Recently some encouraging results from clinical trials of radioimmunotherapy have been reported in the literature. There is a continual search for more avid and specific antibodies, and the techniques of genetic engineering are being applied to the problem of reducing the antigenicity and mass of the carrier antibody. The improved efficiency of the labelled antibody needs to be supplemented by an identification of those tumours most likely to respond to this form of therapy. PMID:3542006

  8. Australian Dialects and Indigenous Creoles: Is There a Place for Non-Standard Australian English in the Lower Secondary English Classroom in Australia?

    ERIC Educational Resources Information Center

    Williams, Lucy J.

    2011-01-01

    There are increasing numbers of students entering Australian secondary schools whose first language is not English. Compound this with the numbers of Indigenous students who speak Creoles or who have distinct dialects, and teachers in secondary English classrooms are facing a struggle to implement the syllabus and engage students. The issue of how…

  9. U.S. DOE 2004 LANL Radionuclide Air Emissions

    SciTech Connect

    K.W. Jacobson

    2005-08-12

    Amendments to the Clean Air Act, which added radionuclides to the National Emissions Standards for Hazardous Air Pollutants (NESHAP), went into effect in 1990. Specifically, a subpart (H) of 40 CFR 61 established an annual limit on the impact to the public attributable to emissions of radionuclides from U.S. Department of Energy facilities, such as the Los Alamos National Laboratory (LANL). As part of the new NESHAP regulations, LANL must submit an annual report to the U.S. Environmental Protection Agency headquarters and the regional office in Dallas by June 30. This report includes results of monitoring at LANL and the dose calculations for the calendar year 2004.

  10. Radionuclide injury to the lung.

    PubMed Central

    Dagle, G E; Sanders, C L

    1984-01-01

    Radionuclide injury to the lung has been studied in rats, hamsters, dogs, mice and baboons. Exposure of the lung to high dose levels of radionuclides produces a spectrum of progressively more severe functional and morphological changes, ranging from radiation pneumonitis and fibrosis to lung tumors. These changes are somewhat similar for different species. Their severity can be related to the absorbed radiation dose (measured in rads) produced by alpha, beta or gamma radiation emanating from various deposited radionuclides. The chemicophysical forms of radionuclides and spatial-temporal factors are also important variables. As with other forms of injury to the lung, repair attempts are highlighted by fibrosis and proliferation of pulmonary epithelium. Lung tumors are the principal late effect observed in experimental animals following pulmonary deposition of radionuclides at dose levels that do not result in early deaths from radiation pneumonitis or fibrosis. The predominant lung tumors described have been of epithelial origin and have been classified, in decreasing frequency of occurrence, as adenocarcinoma, bronchioloalveolar carcinoma, epidermoid carcinomas and combined epidermoid and adenocarcinoma. Mesothelioma and fibrosarcoma have been observed in rats, but less commonly in other species. Hemangiosarcomas were frequency observed in dogs exposed to beta-gamma emitters, and occasionally in rats exposed to alpha emitters. These morphologic changes in the lungs of experimental animals were reviewed and issues relevant to the prediction of human hazards discussed. PMID:6376095

  11. Radionuclide Retention in Concrete Wasteforms

    SciTech Connect

    Wellman, Dawn M.; Jansik, Danielle P.; Golovich, Elizabeth C.; Cordova, Elsa A.

    2012-09-24

    Assessing long-term performance of Category 3 waste cement grouts for radionuclide encasement requires knowledge of the radionuclide-cement interactions and mechanisms of retention (i.e., sorption or precipitation); the mechanism of contaminant release; the significance of contaminant release pathways; how wasteform performance is affected by the full range of environmental conditions within the disposal facility; the process of wasteform aging under conditions that are representative of processes occurring in response to changing environmental conditions within the disposal facility; the effect of wasteform aging on chemical, physical, and radiological properties; and the associated impact on contaminant release. This knowledge will enable accurate prediction of radionuclide fate when the wasteforms come in contact with groundwater. Data collected throughout the course of this work will be used to quantify the efficacy of concrete wasteforms, similar to those used in the disposal of LLW and MLLW, for the immobilization of key radionuclides (i.e., uranium, technetium, and iodine). Data collected will also be used to quantify the physical and chemical properties of the concrete affecting radionuclide retention.

  12. Geomorphic control of radionuclide diffusion in desert soils

    USGS Publications Warehouse

    Pelletier, J.D.; Harrington, C.D.; Whitney, J.W.; Cline, M.; DeLong, S.B.; Keating, G.; Ebert, T.K.

    2005-01-01

    Diffusion is a standard model for the vertical migration of radionuclides in soil profiles. Here we show that diffusivity values inferred from fallout 137CS profiles in soils on the Fortymile Wash alluvial fan, Nye County, Nevada, have a strong inverse correlation with the age of the geomorphic surface. This result suggests that radionuclide-bound particles are predominantly transported by infiltration rather than by bulk-mixing processes such as wetting/ drying, freeze/thaw, and bioturbation. Our results provide a preliminary basis for using soil-geomorphic mapping, point-based calibration data, and the diffusion model to predict radionuclide trans desert soils within a pedotransfer-function approach. Copyright 2005 by the American Geophysical Union.

  13. Deriving cleanup guidelines for radionuclides at Brookhaven National Laboratory

    SciTech Connect

    Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

    1997-01-01

    Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL`s Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory. With the exception of radium, there are no regulations or guidelines to establish cleanup guidelines for radionuclides in soils at BNL. BNL must derive radionuclide soil cleanup guidelines for a number of Operable Units (OUs) and Areas of Concern (AOCs). These guidelines are required by DOE under a proposed regulation for radiation protection of public health and the environment as well as to satisfy the requirements of CERCLA. The objective of this report is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL. Implementation of the approach is briefly discussed.

  14. Radionuclide therapy in neuroendocrine tumours: a systematic review.

    PubMed

    Gulenchyn, K Y; Yao, X; Asa, S L; Singh, S; Law, C

    2012-05-01

    The purpose of this systematic review was to investigate the effects of therapeutic radiopharmaceuticals in patients with different types of advanced neuroendocrine tumour (NETs). A literature search was carried out in MEDLINE and EMBASE from January 1998 to November 2010. The Cochrane Library (to Issue 10, 2010) and the Standards and Guidelines Evidence Inventory of Cancer Guidelines, including over 1100 English-language cancer guidelines from January 2003 to June 2010, were also checked. No existing systematic reviews or clinical practice guidelines based on a systematic review or randomised controlled trials focusing on this topic were found. Twenty-four fully published articles were abstracted and summarised: 16 articles focused on five peptide receptor radionuclide therapy ((111)In-DTPAOC, (90)Y-DOTALAN, (90)Y-DOTATOC, (90)Y-DOTATATE, and (177)Lu-DOTATATE) and eight focused on (131)I-MIBG treatment. Limited evidence from a historical comparison of studies in one centre supported that (177)Lu-DOTATATE might be associated with greater clinical outcomes compared with (90)Y-DOTATOC or (111)In-DTPAOC. The severe toxicities for (177)Lu-DOTATATE included hepatic insufficiency in 0.6%, myelodysplastic syndrome in 0.8% and renal insufficiency in 0.4% of patients in this study. Insufficient evidence suggested efficacy of (131)I-MIBG in adult NET patients, but the overall tumour response rate from (131)I-MIBG was 27-75% for malignant neuroblastoma, paraganglioma or pheochromocytoma. Haematological toxicities were the main severe side-effects after (131)I-MIBG and 4% of patients developed secondary malignancies in one study. To date, peptide receptor radionuclide therapy seems to be an acceptable option and is relatively safe in adult advanced NET patients with receptor uptake positive on scintigraphy, but patients' renal function must be monitored. (131)I-MIBG may be effective for malignant neuroblastoma, paraganglioma or pheochromocytoma, but its side-effects need to be

  15. Radionuclide air emissions report for the Hanford site, Calendar year 1994

    SciTech Connect

    Gleckler, B.P.; Diediker, L.P.; Jette, S.J.; Rhoads, K.; Soldat, S.K.

    1995-06-01

    This report documents radionuclide air emissions from the Hanford Site in 1994, and the resulting effective dose equivalent to the maximally exposed member of the public, referred to as the ``MEI.`` The report has been prepared and will be submitted in accordance with reporting requirements in the Code of Federal Regulations, title 40, Protection of the Environment, Part 61, ``National Emissions Standards for Hazardous Air Pollutants,`` Subpart H, ``National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.``

  16. Radionuclide air emissions report for the Hanford Site, calendar year 1992

    SciTech Connect

    Diediker, L.P.; Johnson, A.R.; Rhoads, K.; Klages, D.L.; Soldat, J.K.; Rokkan, D.J.

    1993-06-01

    This report documents radionuclide air emissions from the Hanford Site in 1992 and the resulting effective dose equivalent to an member of the public. The report has been prepared and will be submitted in accordance with reporting requirements in the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, ``National Emissions Standards for Hazardous Air Pollutants,`` Subpart H, ``National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.``

  17. Radionuclides in Chesapeake Bay sediments

    NASA Technical Reports Server (NTRS)

    Cressy, P. J., Jr.

    1976-01-01

    Natural and manmade gamma-ray emitting radionuclides were measured in Chesapeake Bay sediments taken near the Calvert Cliffs Nuclear Power Plant site. Samples represented several water depths, at six locations, for five dates encompassing a complete seasonal cycle. Radionuclide contents of dry sediments ranged as follows: Tl-208, 40 to 400 pCi/kg; Bi-214, 200 to 800 pCi/kg; K, 0.04 to 2.1 percent; Cs-137 5 to 1900 pCi/kg; Ru106, 40 to 1000 pCikg Co60, 1 to 27 pCi/kg. In general, radionuclide contents were positively correlated with each other and negatively correlated with sediment grain size.

  18. Basalt-radionuclide distribution coefficient determinations. FY-1979 annual report

    SciTech Connect

    Ames, L.L.; McGarrah, J.E.

    1980-09-01

    Experimental radionuclide distribution coefficients (Kd') were determined for Pomona, Flow E, Umtanum basalts, and secondary mineralization associated with Pomona basalt at 23/sup 0/, 60/sup 0/ and 150/sup 0/C. Radionuclides used were /sup 75/Se, /sup 85/Sr, /sup 99/Tc, /sup 125/I, /sup 135/Cs, /sup 226/Ra, /sup 237/Np, /sup 238/U, /sup 241/Am, and /sup 241/Pu. Solution oxygen contents were controlled by the basalt/groundwater system (Eh = 600 to 700 mV), and were high (8.2 to 8.4 mg/l) at 23/sup 0/C. Oxygen contents and pH changed little in contact with basalt. The effects of temperature changes on radionuclide Kd' results varied depending upon the radionuclide involved, solution-solid reactions, and the relationship of the radionuclide to these reactions. For example, cesium Kd' values decreased from 3100 ml/g for Umtanum basalt at 23/sup 0/C to 120 ml/g at 150/sup 0/C. At the same time, strontium Kd' values increased for Umtanum basalt from 105 ml/g at 23/sup 0/C to complete removal at 150/sup 0/C and 40 days. Radionuclide adsorption coefficient measurements at higher temperatures and pressures were made in addition to the 23/sup 0/C, solution-solid contact time-conditional Kd (Kd') measurements. These include Kd' measurements with Umtanum basalt, Pomona basalt, Flow E basalt and secondary mineralization and radioisotopes of americium, cesium, iodine, neptunium, plutonium, radium, selenium, strontium, technetium and uranium. The additional temperatures involved were 60/sup 0/C, 150/sup 0/C, and 300/sup 0/C. At 150/sup 0/C, argon pressures of 6.9, 13.8, 20.7, and 27.6 MPa will be used to ascertain the effects of pressure changes on Kd' values. So far only the 6.9 MPa argon pressure has been investigated. The upper temperature of 250/sup 0/C is where thermal breakdown of dioctahedral smectites (secondary mineralization) begins.

  19. Extinct radionuclides. [in solar system

    NASA Technical Reports Server (NTRS)

    Podosek, F. A.; Swindle, T. D.

    1988-01-01

    Extinct radionuclides, or radioactive isotopes with lifetimes of the order of 1 to 100 Myr that are now extinct in the solar system are discussed. Evidence is presented for the presence of such radionuclides in the early solar system, including Al-26, Mn-53, Pd-107, I-129, Pu-244, and Sm-146. It is suggested that the abundances of these species provide constraints on nucleosynthetic time scales and the history of solar system materials before they became the solar system. The shortest-lived species is Al-26, which may have been sufficiently abundant to be the major heat source for meteorite parent-body metamorphism or igneous differentiation.

  20. Radionuclide labeled lymphocytes for therapeutic use

    DOEpatents

    Srivastava, S.C.; Fawwaz, R.A.; Richards, P.

    1983-05-03

    Lymphocytes labelled with ..beta..-emitting radionuclides are therapeutically useful, particularly for lymphoid ablation. They are prepared by incubation of the lymphocytes with the selected radionuclide-oxine complex.

  1. Conditions and processes affecting radionuclide transport

    USGS Publications Warehouse

    Simmons, Ardyth M.; Neymark, Leonid A.

    2012-01-01

    Understanding of unsaturated-zone transport is based on laboratory and field-scale experiments. Fractures provide advective transport pathways. Sorption and matrix diffusion may contribute to retardation of radionuclides. Conversely, sorption onto mobile colloids may enhance radionuclide transport.

  2. Radionuclide measurement of differential glomerular filtration rate

    SciTech Connect

    Powers, T.A.; Stone, W.J.; Grove, R.B.; Plunkett, J.M.; Kadir, S.; Patton, J.A.; Bowen, R.D.

    1981-01-01

    The authors sought to determine whether radionuclides could provide a reasonable estimate of differential renal function in five normal dogs and six dogs with unilateral segmental renal infarction. Glomerular filtration rate (GFR) of each kidney was measured by the standard technique using constant infusions of 99mTc-DTPA, iothalamate, and creatinine following ureteral catheterization. These results were correlated with total GFR estimated by bolus injection of 99mTc-DTPA and analysis of the plasma 99mTc-DTPA disappearance curve obtained by blood sampling. Differential GFR was then calculated by multiplying the total GFR from double exponential analysis of this curve (DTPA2) by each of three measures of differential function. These include the percent differential uptake of 99mTc-DTPA and 99mTc-DMSA in the posterior projection as well as the geometric mean of 99mTc-DMSA uptake. There were good correlations between differential GFR calculated from iothalamate clearances obtained at ureteral catheterization and all noninvasive methods involving radionuclides and DTPA2 (r = 0.85 - 0.99). Single exponential analysis of the 99mTc-DTPA plasma disappearance curve was less satisfactory. The authors suggest that measurement of total and differential GFR calculated from plasma clearance of 99mTc-DTPA and external counting may be a useful method with potential clinical applications.

  3. [Radionuclide therapy of endocrine-related cancer].

    PubMed

    Kratochwil, C; Giesel, F L

    2014-10-01

    This article gives an overview of the established radionuclide therapies for endocrine-related cancer that already have market authorization or are currently under evaluation in clinical trials. Radioiodine therapy is still the gold standard for differentiated iodine-avid thyroid cancer. In patients with bone and lung metastases (near) total remission is seen in approximately 50% and the 15-year survival rate for these patients is approximately 90%. In contrast to the USA, meta-iodobenzylguanidine (MIBG) therapy has market approval in Europe. According to the current literature, in the setting of advanced stage neuroblastoma and malignant pheochromocytoma or paraganglioma, radiological remission can be achieved in >30% and symptom control in almost 80% of the treated patients. Somatostatin receptor targeted radionuclide therapies (e.g. with DOTATATE or DOTATOC) demonstrated promising results in phase 2 trials, reporting progression-free survival in the range of 24-36 months. A first phase 3 pivotal trial for intestinal carcinoids is currently recruiting and another trial for pancreatic neuroendocrine tumors is planned. Radiopharmaceuticals based on glucagon-like peptide 1 (GLP1) or minigastrins are in the early evaluation stage for application in the treatment of insulinomas and medullary thyroid cancer. In general, radiopharmaceutical therapy belongs to the group of so-called theranostics which means that therapy is tailored for individual patients based on molecular imaging diagnostics to stratify target positive or target negative tumor phenotypes.

  4. Tumor immunotargeting using innovative radionuclides.

    PubMed

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  5. Tumor Immunotargeting Using Innovative Radionuclides

    PubMed Central

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  6. Natural radionuclide accumulation by raindrops

    NASA Astrophysics Data System (ADS)

    Gusev, Anatoly; Martin, Inacio; Shkevov, Rumen; Alves, Mauro

    2016-07-01

    The laboratory of environmental radiation of ITA (São José dos Campos, 23°11'11″S, 45°52'43″W, 650 MAMSL) performs simultaneous monitoring of a natural radiation background and meteorological parameters. A time resolution of up to 1 minute allows a detailed comparison of changes in meteorological parameters with those of a concentration of ambient radon progenies in the atmosphere. Results of a study of variation of a fallout of radon progenies ^{214}Pb and ^{214}Bi concomitanting rainfalls are present. The radionuclide fallout rate is reconstructed from the observed gamma rate through a simulation of the first kind Volterra integral equation with difference kernel, determined by ratio of precipitating rates of 214Pb and 214Bi and their decay half times. An original straightforward step-by-step procedure was used for the numerical solution of the equation. The radionuclide concentration in the rainwater is calculated as a ratio of the reconstructed fallout to the measured rainfall. It was observed that the radionuclide fallout rate increases as the rainfall one in approximately power 0.6, i.e. the same as the mean raindrop volume. The concentration thereafter decreases as the rainfall rate in power 0.4. A numerical simulation of the process of accumulation of the radionuclides during diffusion and coalescence drop growth and aerosol scavenging during a passage from a cloud to the ground was performed. The results of the simulations agree with the experimental data.

  7. TECHNOLOGIES FOR RADON AND RADIONUCLIDE REMOVAL

    EPA Science Inventory

    This paper provides a summary of the technologies that are currently being used to remove radionuclides from drinking water. The radionuclides that are featured are the radionuclides currently regulated by EPA; radium, radon and uranium. Tehnologies effective for removal of eac...

  8. [Role of Radionuclide Technologies in Medicine].

    PubMed

    Chernyaev, A P; Belousov, A V; Varzar, S M; Borchegovskaya, P Y; Nikolaeva, A A; Krusanov, G A

    2016-01-01

    The paper describes the role of radionuclide technologies among the nuclear-physical methods used in medicine. The condition and prospects of the development of nuclear technology with use of radionuclides in medicine, and in particular, the method of brachytherapy are analyzed. The analysis of the current state of applying radionuclide facilities in medicine is provided.

  9. Measurement of radionuclides in waste packages

    DOEpatents

    Brodzinski, Ronald L.; Perkins, Richard W.; Rieck, Henry G.; Wogman, Ned A.

    1986-01-01

    A method is described for non-destructively assaying the radionuclide content of solid waste in a sealed container by analysis of the waste's gamma-ray spectrum and neutron emissions. Some radionuclides are measured by characteristic photopeaks in the gamma-ray spectrum; transuranic nuclides are measured by neutron emission rate; other radionuclides are measured by correlation with those already measured.

  10. Measurement of radionuclides in waste packages

    DOEpatents

    Brodzinski, R.L.; Perkins, R.W.; Rieck, H.G.; Wogman, N.A.

    1984-09-12

    A method is described for non-destructively assaying the radionuclide content of solid waste in a sealed container by analysis of the waste's gamma-ray spectrum and neutron emissions. Some radionuclides are measured by characteristic photopeaks in the gamma-ray spectrum; transuranic nuclides are measured by neutron emission rate; other radionuclides are measured by correlation with those already measured.

  11. Evaluating Radionuclide Air Emission Stack Sampling Systems

    SciTech Connect

    Ballinger, Marcel Y.

    2002-12-16

    The Pacific Northwest National Laboratory (PNNL) operates a number of research and development (R&D) facilities for the U.S. Department of Energy at the Hanford Site, Washington. These facilities are subject to Clean Air Act regulations that require sampling of radionuclide air emissions from some of these facilities. A revision to an American National Standards Institute (ANSI) standard on sampling radioactive air emissions has recently been incorporated into federal and state regulations and a re-evaluation of affected facilities is being performed to determine the impact. The revised standard requires a well-mixed sampling location that must be demonstrated through tests specified in the standard. It also carries a number of maintenance requirements, including inspections and cleaning of the sampling system. Evaluations were performed in 2000 – 2002 on two PNNL facilities to determine the operational and design impacts of the new requirements. The evaluation included inspection and cleaning maintenance activities plus testing to determine if the current sampling locations meet criteria in the revised standard. Results show a wide range of complexity in inspection and cleaning activities depending on accessibility of the system, ease of removal, and potential impact on building operations (need for outages). As expected, these High Efficiency Particulate Air (HEPA)-filtered systems did not show deposition significant enough to cause concerns with blocking of the nozzle or other parts of the system. The tests for sampling system location in the revised standard also varied in complexity depending on accessibility of the sample site and use of a scale model can alleviate many issues. Previous criteria to locate sampling systems at eight duct diameters downstream and two duct diameters upstream of the nearest disturbances is no guarantee of meeting criteria in the revised standard. A computational fluid dynamics model was helpful in understanding flow and

  12. FOREWORD: Special issue on radionuclide metrology

    NASA Astrophysics Data System (ADS)

    Simpson, Bruce; Judge, Steven

    2007-08-01

    the improvement in accuracy and precision of measurement as demanded by the stringent requirements of the user community, such as the correct calibration of nuclear instrumentation. This leads into the need for traceability to national measurement standards maintained by the national metrology institutes. As part of the radioactivity traceability chain, as for all areas of metrology, it is vital that systems are in place to ensure that national standards can be checked for worldwide uniformity and measurement equivalence. Many of the resulting areas are covered by the topics in this special issue, although specifically excluded from the scope of the publication are topics that are widely covered in other publications due to their application in applied metrology—for example, radiochemistry, environmental gamma spectrometry and alpha spectrometry. There are three sections to this issue, starting with papers on how the CIPM Mutual Recognition Arrangement has been implemented for radionuclide metrology, following into the bulk of the publication with articles on the `state of the art' in radionuclide metrology and ending with traceability to national/international standards in nuclear medicine, environmental monitoring, radiation protection and decommissioning. This special issue in essence follows on from earlier BIPM Monographies that were published in order to provide the base information for radionuclide metrology. In many respects they complement the special issue since much of their content is still valid today, particularly those published more recently as an aid to ensuring consistency of method and data. The BIPM Monographies are freely available to download from the BIPM website at http://www.bipm.org/en/publications/monographies-ri.html. The papers in the special issue draw on the experience of radionuclide metrologists who have been involved in their area of expertise for many years. The authors give readers an insightful account of the selected topics

  13. Exploring the Relationship between Access Technology and Standardized Test Scores for Youths with Visual Impairments: Secondary Analysis of the National Longitudinal Transition Study 2

    ERIC Educational Resources Information Center

    Freeland, Amy L.; Emerson, Robert Wall; Curtis, Amy B.; Fogarty, Kieran

    2010-01-01

    This article presents the findings of a secondary analysis of the National Longitudinal Transition Study 2 that explored the predictive association between training in access technology and performance on the Woodcock-Johnson Tests of Academic Achievement: III. The results indicated that the use of access technology had a limited predictive…

  14. 40 CFR Appendix H to Part 50 - Interpretation of the 1-Hour Primary and Secondary National Ambient Air Quality Standards for Ozone

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT... determining the expected number of annual exceedances relate to accounting for incomplete sampling. In general... waiver of the ozone monitoring requirement would be handled under provisions of 40 CFR, part 58....

  15. 40 CFR 197.20 - What standard must DOE meet?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS PUBLIC HEALTH AND ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR YUCCA MOUNTAIN, NEVADA Public... assessment must include all potential pathways of radionuclide transport and exposure....

  16. Identification of CSF fistulas by radionuclide counting

    SciTech Connect

    Yamamoto, Y.; Kunishio, K.; Sunami, N.; Yamamoto, Y.; Satoh, T.; Suga, M.; Asari, S. )

    1990-07-01

    A radionuclide counting method, performed with the patient prone and the neck flexed, was used successfully to diagnose CSF rhinorrhea in two patients. A normal radionuclide ratio (radionuclide counts in pledget/radionuclide counts in 1-ml blood sample) was obtained in 11 normal control subjects. Significance was determined to be a ratio greater than 0.37. Use of radionuclide counting method of determining CSF rhinorrhea is recommended when other methods have failed to locate a site of leakage or when posttraumatic meningitis suggests subclinical CSF rhinorrhea.

  17. Quality assurance/quality control of foot and mouth disease solid phase competition enzyme-linked immunosorbent assay--Part I. Quality assurance: development of secondary and working standards.

    PubMed

    Goris, N; De Clercq, K

    2005-12-01

    International movement in animals and animal products has urged organisations like the World Organisation for Animal Health (OIE) to draw up guidelines to regulate and facilitate trade between Member Countries. However, as the global market continues to grow, further standardisation and harmonisation of antibody detection assays for infectious diseases are needed, especially regarding the development and use of reference materials. For OIE notifiable diseases for which primary or international reference standards are available or under development, National or Regional Reference Laboratories are encouraged to establish their own secondary and/or working standards. This paper describes the development of standards for the foot and mouth disease (FMD) solid phase competition enzyme-linked immunosorbent assay using positive serum obtained from calves vaccinated against the FMD virus. The procedure outlined in this manuscript can easily be extrapolated to similar serological assays and should lead to further international harmonisation of assays and test results.

  18. Secondary parkinsonism

    MedlinePlus

    Parkinsonism - secondary; Atypical Parkinson disease ... to be less responsive to medical therapy than Parkinson disease. ... Unlike Parkinson disease, some types of secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Brain ...

  19. Critical comparison of radiometric and mass spectrometric methods for the determination of radionuclides in environmental, biological and nuclear waste samples.

    PubMed

    Hou, Xiaolin; Roos, Per

    2008-02-11

    The radiometric methods, alpha (alpha)-, beta (beta)-, gamma (gamma)-spectrometry, and mass spectrometric methods, inductively coupled plasma mass spectrometry, accelerator mass spectrometry, thermal ionization mass spectrometry, resonance ionization mass spectrometry, secondary ion mass spectrometry, and glow discharge mass spectrometry are reviewed for the determination of radionuclides. These methods are critically compared for the determination of long-lived radionuclides important for radiation protection, decommissioning of nuclear facilities, repository of nuclear waste, tracer application in the environmental and biological researches, these radionuclides include (3)H, (14)C, (36)Cl, (41)Ca, (59,63)Ni, (89,90)Sr, (99)Tc, (129)I, (135,137)Cs, (210)Pb, (226,228)Ra, (237)Np, (241)Am, and isotopes of thorium, uranium and plutonium. The application of on-line methods (flow injection/sequential injection) for separation of radionuclides and automated determination of radionuclides is also discussed.

  20. Critical comparison of radiometric and mass spectrometric methods for the determination of radionuclides in environmental, biological and nuclear waste samples.

    PubMed

    Hou, Xiaolin; Roos, Per

    2008-02-11

    The radiometric methods, alpha (alpha)-, beta (beta)-, gamma (gamma)-spectrometry, and mass spectrometric methods, inductively coupled plasma mass spectrometry, accelerator mass spectrometry, thermal ionization mass spectrometry, resonance ionization mass spectrometry, secondary ion mass spectrometry, and glow discharge mass spectrometry are reviewed for the determination of radionuclides. These methods are critically compared for the determination of long-lived radionuclides important for radiation protection, decommissioning of nuclear facilities, repository of nuclear waste, tracer application in the environmental and biological researches, these radionuclides include (3)H, (14)C, (36)Cl, (41)Ca, (59,63)Ni, (89,90)Sr, (99)Tc, (129)I, (135,137)Cs, (210)Pb, (226,228)Ra, (237)Np, (241)Am, and isotopes of thorium, uranium and plutonium. The application of on-line methods (flow injection/sequential injection) for separation of radionuclides and automated determination of radionuclides is also discussed. PMID:18215644

  1. Radionuclide synovectomy - essentials for rheumatologists.

    PubMed

    Chojnowski, Marek M; Felis-Giemza, Anna; Kobylecka, Małgorzata

    2016-01-01

    Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common arthropathies can also benefit from this method. Radiosynovectomy is safe, well tolerated and efficacious. About 70-80% of patients respond well to the therapy. However, the therapeutic effects are considerably worse in patients with co-existent osteoarthritis and advanced joint degeneration. Despite its advantages, radionuclide synovectomy is not performed as often as it could be, so greater knowledge and understanding of this method are needed. The authors present the most important facts about radiosynovectomy that may help rheumatologists in their daily clinical practice. PMID:27504020

  2. A new experimental procedure for determination of photoelectric efficiency of a NaI(Tl) detector used for nuclear medicine liquid waste monitoring with traceability to a reference standard radionuclide calibrator.

    PubMed

    Ceccatelli, A; Campanella, F; Ciofetta, G; Marracino, F M; Cannatà, V

    2010-02-01

    To determine photopeak efficiency for (99m)Tc of the NaI(Tl) detector used for liquid waste monitoring at the Nuclear Medicine Unit of IRCCS Paediatric Hospital Bambino Gesù in Rome, a specific experimental procedure, with traceability to primary standards, was developed. Working with the Italian National Institute for Occupational Prevention and Safety, two different calibration source geometries were employed and the detector response dependence on geometry was investigated. The large percentage difference (almost 40%) between the two efficiency values obtained showed that geometrical effects cannot be neglected.

  3. Natural chelates for radionuclide decorporation

    DOEpatents

    Premuzic, E.T.

    1983-08-25

    This invention relates to the method and resulting chelates of desorbing a radionuclide selected from thorium, uranium, and plutonium containing cultures in a bioavailable form involving pseudomonas or other microorganisms. A preferred microorganism is Pseudomonas aeruginosa which forms multiple chelates with thorium in the range of molecular weight 1000 to 1000 and also forms chelates with uranium of molecular weight in the area of 100 to 1000 and 1000 to 2000.

  4. Chernobyl radionuclide distribution and migration.

    PubMed

    Izrael, Yury A

    2007-11-01

    The accident at Unit No. 4 of the Chernobyl Nuclear Power Plant on 26 April 1986 presented severe challenges in radiation protection. Early activity measurements defined the contaminated areas in order to determine what persons should be evacuated on the basis of the exposure limit at that time of 100 mSv (10 rem) for accidents. The immediate definition of these areas was accomplished with specially equipped aircraft capable of measuring external gamma-exposure rate and radionuclide spectra. Over time, maps of 137Cs contamination (the most important long-lived radionuclide) have become more and more sophisticated and have been used for further determinations of the control of the consequences of the accident. About 70% of the total release of 137Cs was deposited in Belarus, the Russian Federation, and Ukraine; but there was also widespread deposition throughout the countries of Western Europe. Two atlases of contamination throughout Europe were prepared, and the Russian atlas included data on other radionuclides and on external gamma-exposure rates. The radiocesiums behaved as volatile radionuclides because of the volatility of cesium. In contrast to the typical pattern after nuclear weapons tests, 90Sr behaved only as a refractory element, as its volatile precursors krypton and rubidium had already decayed within the reactor. Nearly all of the refractory elements (strontium, plutonium, etc.) released by the accident were confined to the 30-km zone around the reactor. A proposal is made to develop a more complete atlas of 137Cs deposition from the accident that would include the entire Northern Hemisphere. Water was not an important vector of exposure to human beings following the accident. PMID:18049217

  5. Peptide Receptor Radionuclide Therapy in the Treatment of Neuroendocrine Tumors.

    PubMed

    Kwekkeboom, Dik J; Krenning, Eric P

    2016-02-01

    Peptide receptor radionuclide therapy (PRRT) is a promising new treatment modality for inoperable or metastasized gastroenteropancreatic neuroendocrine tumors patients. Most studies report objective response rates in 15% to 35% of patients. Progression-free (PFS) and overall survival (OS) compare favorably with that for somatostatin analogues, chemotherapy, or newer, "targeted" therapies. Prospective, randomized data regarding the potential PFS and OS benefit of PRRT compared with standard therapies is anticipated.

  6. Radionuclide daughter inventory generator code: DIG

    SciTech Connect

    Fields, D.E.; Sharp, R.D.

    1985-09-01

    The Daughter Inventory Generator (DIG) code accepts a tabulation of radionuclide initially present in a waste stream, specified as amounts present either by mass or by activity, and produces a tabulation of radionuclides present after a user-specified elapsed time. This resultant radionuclide inventory characterizes wastes that have undergone daughter ingrowth during subsequent processes, such as leaching and transport, and includes daughter radionuclides that should be considered in these subsequent processes or for inclusion in a pollutant source term. Output of the DIG code also summarizes radionuclide decay constants. The DIG code was developed specifically to assist the user of the PRESTO-II methodology and code in preparing data sets and accounting for possible daughter ingrowth in wastes buried in shallow-land disposal areas. The DIG code is also useful in preparing data sets for the PRESTO-EPA code. Daughter ingrowth in buried radionuclides and in radionuclides that have been leached from the wastes and are undergoing hydrologic transport are considered, and the quantities of daughter radionuclide are calculated. Radionuclide decay constants generated by DIG and included in the DIG output are required in the PRESTO-II code input data set. The DIG accesses some subroutines written for use with the CRRIS system and accesses files containing radionuclide data compiled by D.C. Kocher. 11 refs.

  7. RADIONUCLIDE AIR EMISSIONS REPORT FOR THE HANFORD SITE CY2003

    SciTech Connect

    ROKKAN, D.J.

    2004-06-11

    This report documents radionuclide air emissions from the US Department of Energy (DOE) Hanford Site in 2003 and the resulting effective dose equivalent (EDE) to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants, Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities''; Washington Administrative Code (WAC) Chapter 246-247, ''Radiation Protection-Air Emissions''; 10 CFR 830.120, Quality Assurance; DOE Order 414.1B, Quality Assurance; NQA-1, Quality Assurance Requirements for Nuclear Facility Application; EPA QA/R-2, EPA Requirements for Quality Management Plans; and EPA QA/R-5, Requirements for Quality Assurance Project Plans. The federal regulations in Subpart H of 40 CFR 61 require the measurement and reporting of radionuclides emitted from DOE facilities and the resulting public dose from those emissions. A standard of 10 mrem/yr EDE is not to be exceeded. The EDE to the MEI due to routine and nonroutine emissions in 2003 from Hanford Site point sources was 0.022 mrem (0.00022 mSv), or 0.22 percent of the federal standard. The portions of the Hanford Site MEI dose attributable to individual point sources as listed in Section 2.0 are appropriate for use in demonstrating the compliance of abated stack emissions with applicable terms of the Hanford Site Air Operating Permit and of Notices of Construction. The state has adopted the 40 CFR 61 standard of 10 mrem/yr EDE into their regulations, yet further requires that the EDE to the MEI be calculated not only from point source emissions but also from diffuse and fugitive sources of emissions. WAC 246-247 also requires the reporting of radionuclide emissions from all Hanford Site sources during routine as well as nonroutine operations. The EDE from

  8. Standardization of Sn-113.

    PubMed

    Roteta, Miguel; Peyres, Virginia; García-Toraño, Eduardo

    2014-05-01

    The radionuclide (113)Sn is a quasi-monoenergetic gamma emitter often used in the efficiency calibration of gamma spectrometers in the energy region around 390keV. This paper presents the results of the standardization of this radionuclide by three methods: integral (4π-γ) counting with a well-type NaI(Tl) detector, liquid scintillation counting applying the CIEMAT-NIST method and 4π coincidence counting (conversion electron-X) with a digital coincidence system. PMID:24365465

  9. Methods of separating short half-life radionuclides from a mixture of radionuclides

    DOEpatents

    Bray, L.A.; Ryan, J.L.

    1998-09-15

    The present invention is a method of obtaining a radionuclide product selected from the group consisting of {sup 223}Ra and {sup 225}Ac, from a radionuclide ``cow`` of {sup 227}Ac or {sup 229}Th respectively. The method comprises the steps of (a) permitting ingrowth of at least one radionuclide daughter from said radionuclide ``cow`` forming an ingrown mixture; (b) insuring that the ingrown mixture is a nitric acid ingrown mixture; (c) passing the nitric acid ingrown mixture through a first nitrate form ion exchange column which permits separating the ``cow`` from at least one radionuclide daughter; (d) insuring that the at least one radionuclide daughter contains the radionuclide product; (e) passing the at least one radionuclide daughter through a second ion exchange column and separating the at least one radionuclide daughter from the radionuclide product and (f) recycling the at least one radionuclide daughter by adding it to the ``cow``. In one embodiment the radionuclide ``cow`` is the {sup 227}Ac, the at least one daughter radionuclide is a {sup 227}Th and the product radionuclide is the {sup 223}Ra and the first nitrate form ion exchange column passes the {sup 227}Ac and retains the {sup 227}Th. In another embodiment the radionuclide ``cow`` is the {sup 229}Th, the at least one daughter radionuclide is a {sup 225}Ra and said product radionuclide is the {sup 225}Ac and the {sup 225}Ac and nitrate form ion exchange column retains the {sup 229}Th and passes the {sup 225}Ra/Ac. 8 figs.

  10. Methods of separating short half-life radionuclides from a mixture of radionuclides

    DOEpatents

    Bray, Lane A.; Ryan, Jack L.

    1998-01-01

    The present invention is a method of obtaining a radionuclide product selected from the group consisting of .sup.223 Ra and .sup.225 Ac, from a radionuclide "cow" of .sup.227 Ac or .sup.229 Th respectively. The method comprises the steps of a) permitting ingrowth of at least one radionuclide daughter from said radionuclide "cow" forming an ingrown mixture; b) insuring that the ingrown mixture is a nitric acid ingrown mixture; c) passing the nitric acid ingrown mixture through a first nitrate form ion exchange column which permits separating the "cow" from at least one radionuclide daughter; d) insuring that the at least one radionuclide daughter contains the radionuclide product; e) passing the at least one radionuclide daughter through a second ion exchange column and separating the at least one radionuclide daughter from the radionuclide product and f) recycling the at least one radionuclide daughter by adding it to the "cow". In one embodiment the radionuclide "cow" is the .sup.227 Ac, the at least one daughter radionuclide is a .sup.227 Th and the product radionuclide is the .sup.223 Ra and the first nitrate form ion exchange column passes the .sup.227 Ac and retains the .sup.227 Th. In another embodiment the radionuclide "cow"is the .sup.229 Th, the at least one daughter radionuclide is a .sup.225 Ra and said product radionuclide is the .sup.225 Ac and the .sup.225 Ac and nitrate form ion exchange column retains the .sup.229 Th and passes the .sup.225 Ra/Ac.

  11. Microbial Transformations of Actinides and Other Radionuclides

    SciTech Connect

    Francis,A.J.; Dodge, C. J.

    2009-01-07

    Microorganisms can affect the stability and mobility of the actinides and other radionuclides released from nuclear fuel cycle and from nuclear fuel reprocessing plants. Under appropriate conditions, microorganisms can alter the chemical speciation, solubility and sorption properties and thus could increase or decrease the concentrations of radionuclides in solution in the environment and the bioavailability. Dissolution or immobilization of radionuclides is brought about by direct enzymatic action or indirect non-enzymatic action of microorganisms. Although the physical, chemical, and geochemical processes affecting dissolution, precipitation, and mobilization of radionuclides have been extensively investigated, we have only limited information on the effects of microbial processes and biochemical mechanisms which affect the stability and mobility of radionuclides. The mechanisms of microbial transformations of the major and minor actinides U, Pu, Cm, Am, Np, the fission products and other radionuclides such as Ra, Tc, I, Cs, Sr, under aerobic and anaerobic conditions in the presence of electron donors and acceptors are reviewed.

  12. Targeted Radionuclide Therapy of Human Tumors

    PubMed Central

    Gudkov, Sergey V.; Shilyagina, Natalya Yu.; Vodeneev, Vladimir A.; Zvyagin, Andrei V.

    2015-01-01

    Targeted radionuclide therapy is one of the most intensively developing directions of nuclear medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy causes less collateral damage to normal tissues and allows targeted drug delivery to a clinically diagnosed neoplastic malformations, as well as metastasized cells and cellular clusters, thus providing systemic therapy of cancer. The methods of targeted radionuclide therapy are based on the use of molecular carriers of radionuclides with high affinity to antigens on the surface of tumor cells. The potential of targeted radionuclide therapy has markedly grown nowadays due to the expanded knowledge base in cancer biology, bioengineering, and radiochemistry. In this review, progress in the radionuclide therapy of hematological malignancies and approaches for treatment of solid tumors is addressed. PMID:26729091

  13. Targeted Radionuclide Therapy of Human Tumors.

    PubMed

    Gudkov, Sergey V; Shilyagina, Natalya Yu; Vodeneev, Vladimir A; Zvyagin, Andrei V

    2015-12-28

    Targeted radionuclide therapy is one of the most intensively developing directions of nuclear medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy causes less collateral damage to normal tissues and allows targeted drug delivery to a clinically diagnosed neoplastic malformations, as well as metastasized cells and cellular clusters, thus providing systemic therapy of cancer. The methods of targeted radionuclide therapy are based on the use of molecular carriers of radionuclides with high affinity to antigens on the surface of tumor cells. The potential of targeted radionuclide therapy has markedly grown nowadays due to the expanded knowledge base in cancer biology, bioengineering, and radiochemistry. In this review, progress in the radionuclide therapy of hematological malignancies and approaches for treatment of solid tumors is addressed.

  14. Chemical speciation of radionuclides migrating in groundwaters

    SciTech Connect

    Robertson, D.; Schilk, A.; Abel, K.; Lepel, E.; Thomas, C.; Pratt, S.; Cooper, E.; Hartwig, P.; Killey, R.

    1994-04-01

    In order to more accurately predict the rates and mechanisms of radionuclide migration from low-level waste disposal facilities via groundwater transport, ongoing studies are being conducted at field sites at Chalk River Laboratories to identify and characterize the chemical speciation of mobile, long-lived radionuclides migrating in groundwaters. Large-volume water sampling techniques are being utilized to separate and concentrate radionuclides into particular, cationic, anionic, and nonionic chemical forms. Most radionuclides are migrating as soluble, anionic species that appear to be predominantly organoradionuclide complexes. Laboratory studies utilizing anion exchange chromatography have separated several anionically complexed radionuclides, e.g., {sup 60}Co and {sup 106}Ru, into a number of specific compounds or groups of compounds. Further identification of the anionic organoradionuclide complexes is planned utilizing high resolution mass spectrometry. Large-volume ultra-filtration experiments are characterizing the particulate forms of radionuclides being transported in these groundwaters.

  15. [Secondary hypertension].

    PubMed

    Yoshida, Yuichi; Shibata, Hirotaka

    2015-11-01

    Hypertension is a common disease and a crucial predisposing factor of cardiovascular diseases. Approximately 10% of hypertensive patients are secondary hypertension, a pathogenetic factor of which can be identified. Secondary hypertension consists of endocrine, renal, and other diseases. Primary aldosteronism, Cushing's syndrome, pheochromocytoma, hyperthyroidism, and hypothyroidism result in endocrine hypertension. Renal parenchymal hypertension and renovascular hypertension result in renal hypertension. Other diseases such as obstructive sleep apnea syndrome are also very prevalent in secondary hypertension. It is very crucial to find and treat secondary hypertension at earlier stages since most secondary hypertension is curable or can be dramatically improved by specific treatment. One should keep in mind that screening of secondary hypertension should be done at least once in a daily clinical practice. PMID:26619670

  16. Review of Distribution Coefficients for Radionuclides in Carbonate Minerals

    SciTech Connect

    Sutton, M

    2009-08-14

    An understanding of the transport of radionuclides in carbonate minerals is necessary to be able to predict the fate of (and potentially remediate) radionuclides in the environment. In some environments, carbonate minerals such as calciate, aragonite, dolomite and limestone are present and an understanding of the sorption of radionuclides in these carbonate minerals is therefore advantageous. A list of the radionuclides of interest is given in Table 1. The distribution coefficient, K{sub d} is defined as the ratio of the contaminant concentration bound on the solid phase to the contaminant concentration remaining in the liquid phase at equilibrium. Some authors report distribution coefficients and other report partition coefficients, the data presented in this work assumes equality between these two terms, and data are presented and summarized in this work as logarithmic distribution coefficient (log K{sub D}). Published literature was searched using two methods. Firstly, the JNC Sorption Database, namely Shubutani et al (1999), and Suyama and Sasamoto (2004) was used to select elements of interest and a number of carbonate minerals. Secondly, on-line literature search tools were used to locate relevant published articles from 1900 to 2009. Over 300 data points covering 16 elements (hydrogen, carbon, calcium, nickel, strontium, technetium, palladium, iodine, cesium, samarium, europium, holmium, uranium, neptunium, plutonium and americium) were used to calculate an average and range of log K{sub d} values for each element. Unfortunately, no data could be found for chlorine, argon, krypton, zirconium, niobium, tin, thorium and curium. A description of the data is given below, together with the average, standard deviation, minimum, maximum and number of inputs for radionuclide K{sub d} values for calcite, aragonate, limestone, dolomite and unidentified carbonate rocks in Table 2. Finally, the data are condensed into one group (carbonate minerals) of data for each

  17. Colloid labelled with radionuclide and method

    DOEpatents

    Atcher, R.W.; Hines, J.J.

    1990-11-13

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints. No Drawings

  18. Colloid labelled with radionuclide and method

    DOEpatents

    Atcher, Robert W.; Hines, John J.

    1990-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  19. Method of making colloid labeled with radionuclide

    DOEpatents

    Atcher, Robert W.; Hines, John J.

    1991-01-01

    A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

  20. Ion binding compounds, radionuclide complexes, methods of making radionuclide complexes, methods of extracting radionuclides, and methods of delivering radionuclides to target locations

    DOEpatents

    Chen, Xiaoyuan; Wai, Chien M.; Fisher, Darrell R.

    2000-01-01

    The invention pertains to compounds for binding lanthanide ions and actinide ions. The invention further pertains to compounds for binding radionuclides, and to methods of making radionuclide complexes. Also, the invention pertains to methods of extracting radionuclides. Additionally, the invention pertains to methods of delivering radionuclides to target locations. In one aspect, the invention includes a compound comprising: a) a calix[n]arene group, wherein n is an integer greater than 3, the calix[n]arene group comprising an upper rim and a lower rim; b) at least one ionizable group attached to the lower rim; and c) an ion selected from the group consisting of lanthanide and actinide elements bound to the ionizable group. In another aspect, the invention includes a method of extracting a radionuclide, comprising: a) providing a sample comprising a radionuclide; b) providing a calix[n]arene compound in contact with the sample, wherein n is an integer greater than 3; and c) extracting radionuclide from the sample into the calix[n]arene compound. In yet another aspect, the invention includes a method of delivering a radionuclide to a target location, comprising: a) providing a calix[n]arene compound, wherein n is an integer greater than 3, the calix[n]arene compound comprising at least one ionizable group; b) providing a radionuclide bound to the calix[n]arene compound; and c) providing an antibody attached to the calix[n]arene compound, the antibody being specific for a material found at the target location.

  1. Therapy for incorporated radionuclides: scope and need

    SciTech Connect

    Smith, V.H.

    1981-03-01

    In the United States the recent termination of funding for research on therapy for incorporated radionuclides has virtually halted progress on improved or new agents and procedures for removing radioactivity from the body. Research was eliminated, but is still needed on new removal agents, improved delivery system, in vitro test systems, and the toxicology of treatments. For many radionuclides, no adequate therapy exists. The relationship between radionuclide removal and reduction in cancer risk is still unanswered. Without proper research support, needed improvements in the treatment for incorporated radionuclides in the US are uncertain.

  2. Radionuclide transit: a sensitive screening test for esophageal dysfunction

    SciTech Connect

    Russell, C.O.; Hill, L.D.; Holmes, E.R. III; Hull, D.A.; Gannon, R.; Pope, C.E. II

    1981-05-01

    The purpose of this study was to extend existing nuclear medicine techniques for the diagnosis of esophageal motor disorders. A standard homogeneous bolus of 99mtechnetium sulfur colloid in water was swallowed in the supine position under the collimator of a gamma camera linked to a microprocessor. Bolus transit was recorded at 0.4-s intervals, and the movie obtained was used to analyze transit in an objective manner. Ten normal volunteers and 30 subjects with dysphagia not related to mechanical obstruction were studied with this technique. Radionuclide transit studies detected a higher incidence of esophageal motor abnormality than manometry or radiology in the dysphagia group. In addition a definitive description of the functional problem was possible in most cases. Radionuclide transit is a safe noninvasive test and suitable as a screening test for esophageal motor disorders.

  3. Pacific Northwest Laboratory facilities radionuclide inventory assessment CY 1992-1993

    SciTech Connect

    Sula, M.J.; Jette, S.J.

    1994-09-01

    Assessments for evaluating compliance with airborne radionuclide emission monitoring requirements in the National Emission Standards for Hazardous Air Pollutants (NESHAPs - U.S. Code of Federal Regulations, Title 40 Part 61, Subparts H and I) were performed for 33 buildings at the U.S. Department of Energy`s (DOE) Pacific Northwest Laboratory on the Hanford Site, and for five buildings owned and operated by Battelle, Pacific Northwest Laboratories in Richland, Washington. The assessments were performed using building radionuclide inventory data obtained in 1992 and 1993. Results of the assessments are summarized in Table S.1 for DOE-PNL buildings and in Table S.2 for Battelle-owned buildings. Based on the radionuclide inventory assessments, four DOE-PNL buildings (one with two emission points) require continuous sampling for radionuclides per 40 CFR 61. None of the Battelle-owned buildings require continuous emission sampling.

  4. Real time cardiac radionuclide imaging

    SciTech Connect

    Jarkewicz, G.G.

    1986-04-29

    A data acquisition system is described for use in radionuclide cardiac imaging of a patient having been administered a myocardium specific radionuclide, comprising: (a) means for monitoring the electrical activity of the heart; (b) first temporary storage means for accumulating respective pages of data corresponding to nuclear events during each cardiac cycle; (c) means, responsive to the means for monitoring, for determining the time duration of each successive cardiac cycle; (d) means for comparing each determined duration of a cardiac cycle with a preselected time duration range; (e) second temporary storage means; and (f) means for conditionally transferring pages of data from the first temporary storage means to the second temporary storage means if the measured duration associated with each page has predetermined correspondence with the preselected duration range, whereby pages of data having the predetermined correspondence may be collated into a quasi-real time study, while pages of data having different correspondence with the preselected time duration range are discarded from the study.

  5. Hysterosalpingo-radionuclide scintigraphy (HERS)

    SciTech Connect

    Iturralde, M.; Venter, P.F.

    1981-10-01

    A radionuclide procedure, hysterosalpingo-radionuclide scintigraphy (HERS), was designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries as well as to image and functionally outline the patency of the pathways between these two extremes of the female reproductive system. Technetium-99m human albumin microspheres (99mTc-HAM) were deposited in the posterior fornices of patients who were divided into two specific groups. Group I consisted of patients who were to undergo different elective gynecologic operations, in which besides obtaining sequential images, radioactivity levels were measured in the removed organs and tissues. Group II consisted of patients referred by the Infertility Clinic for evaluation of their reproductive system pathways patency. In this latter group, HERS was compared with contrast hysterosalpingography (HSG) and peritoneoscopy (PCP). The results obtained from measurements of radioactivity levels on the removed surgical specimens and comparison with other conventional gynecologic diagnostic procedures provide accurate evidence of the migration of 99mTc-HAM from the vagina, through the uterus and tubes, to the peritoneal cavity and ovaries, and show that HERS is a simple noninvasive method for functionally imaging and assessing the patency of the female reproductive system pathways.

  6. 40 CFR 61.102 - Standard.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....102 Standard. (a) Emissions of radionuclides, including iodine, to the ambient air from a facility... receive in any year an effective dose equivalent of 10 mrem/yr. (b) Emissions of iodine to the ambient...

  7. 40 CFR 61.102 - Standard.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....102 Standard. (a) Emissions of radionuclides, including iodine, to the ambient air from a facility... receive in any year an effective dose equivalent of 10 mrem/yr. (b) Emissions of iodine to the ambient...

  8. 40 CFR 61.102 - Standard.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....102 Standard. (a) Emissions of radionuclides, including iodine, to the ambient air from a facility... receive in any year an effective dose equivalent of 10 mrem/yr. (b) Emissions of iodine to the ambient...

  9. 40 CFR 61.102 - Standard.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....102 Standard. (a) Emissions of radionuclides, including iodine, to the ambient air from a facility... receive in any year an effective dose equivalent of 10 mrem/yr. (b) Emissions of iodine to the ambient...

  10. 40 CFR 61.102 - Standard.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....102 Standard. (a) Emissions of radionuclides, including iodine, to the ambient air from a facility... receive in any year an effective dose equivalent of 10 mrem/yr. (b) Emissions of iodine to the ambient...

  11. Modeling Radionuclide Decay Chain Migration Using HYDROGEOCHEM

    NASA Astrophysics Data System (ADS)

    Lin, T. C.; Tsai, C. H.; Lai, K. H.; Chen, J. S.

    2014-12-01

    Nuclear technology has been employed for energy production for several decades. Although people receive many benefits from nuclear energy, there are inevitably environmental pollutions as well as human health threats posed by the radioactive materials releases from nuclear waste disposed in geological repositories or accidental releases of radionuclides from nuclear facilities. Theoretical studies have been undertaken to understand the transport of radionuclides in subsurface environments because that the radionuclide transport in groundwater is one of the main pathway in exposure scenarios for the intake of radionuclides. The radionuclide transport in groundwater can be predicted using analytical solution as well as numerical models. In this study, we simulate the transport of the radionuclide decay chain using HYDROGEOCHEM. The simulated results are verified against the analytical solution available in the literature. Excellent agreements between the numerical simulation and the analytical are observed for a wide spectrum of concentration. HYDROGECHEM is a useful tool assessing the ecological and environmental impact of the accidental radionuclide releases such as the Fukushima nuclear disaster where multiple radionuclides leaked through the reactor, subsequently contaminating the local groundwater and ocean seawater in the vicinity of the nuclear plant.

  12. The Causal Effect of Student Mobility on Standardized Test Performance: A Case Study with Possible Implications for Accountability Mandates within the Elementary and Secondary Education Act.

    PubMed

    Selya, Arielle S; Engel-Rebitzer, Eden; Dierker, Lisa; Stephen, Eric; Rose, Jennifer; Coffman, Donna L; Otis, Mindy

    2016-01-01

    This paper presents a limited case study examining the causal inference of student mobility on standardized test performance, within one middle-class high school in suburban Connecticut. Administrative data were used from a district public high school enrolling 319 10th graders in 2010. Propensity score methods were used to estimate the causal effect of student mobility on Math, Science, Reading, and Writing portions of the Connecticut Academic Performance Test (CAPT), after matching mobile vs. stable students on gender, race/ethnicity, eligibility for free/reduced lunches, and special education status. Analyses showed that mobility was associated with lower performance in the CAPT Writing exam. Follow-up analyses revealed that this trend was only significant among those who were ineligible for free/reduced lunches, but not among eligible students. Additionally, mobile students who were ineligible for free/reduced lunches had lower performance in the CAPT Science exam according to some analyses. Large numbers of students transferring into a school district may adversely affect standardized test performance. This is especially relevant for policies that affect student mobility in schools, given the accountability measures in the No Child Left Behind that are currently being re-considered in the recent Every Student Succeeds Act.

  13. The Causal Effect of Student Mobility on Standardized Test Performance: A Case Study with Possible Implications for Accountability Mandates within the Elementary and Secondary Education Act

    PubMed Central

    Selya, Arielle S.; Engel-Rebitzer, Eden; Dierker, Lisa; Stephen, Eric; Rose, Jennifer; Coffman, Donna L.; Otis, Mindy

    2016-01-01

    This paper presents a limited case study examining the causal inference of student mobility on standardized test performance, within one middle-class high school in suburban Connecticut. Administrative data were used from a district public high school enrolling 319 10th graders in 2010. Propensity score methods were used to estimate the causal effect of student mobility on Math, Science, Reading, and Writing portions of the Connecticut Academic Performance Test (CAPT), after matching mobile vs. stable students on gender, race/ethnicity, eligibility for free/reduced lunches, and special education status. Analyses showed that mobility was associated with lower performance in the CAPT Writing exam. Follow-up analyses revealed that this trend was only significant among those who were ineligible for free/reduced lunches, but not among eligible students. Additionally, mobile students who were ineligible for free/reduced lunches had lower performance in the CAPT Science exam according to some analyses. Large numbers of students transferring into a school district may adversely affect standardized test performance. This is especially relevant for policies that affect student mobility in schools, given the accountability measures in the No Child Left Behind that are currently being re-considered in the recent Every Student Succeeds Act. PMID:27486427

  14. The Causal Effect of Student Mobility on Standardized Test Performance: A Case Study with Possible Implications for Accountability Mandates within the Elementary and Secondary Education Act.

    PubMed

    Selya, Arielle S; Engel-Rebitzer, Eden; Dierker, Lisa; Stephen, Eric; Rose, Jennifer; Coffman, Donna L; Otis, Mindy

    2016-01-01

    This paper presents a limited case study examining the causal inference of student mobility on standardized test performance, within one middle-class high school in suburban Connecticut. Administrative data were used from a district public high school enrolling 319 10th graders in 2010. Propensity score methods were used to estimate the causal effect of student mobility on Math, Science, Reading, and Writing portions of the Connecticut Academic Performance Test (CAPT), after matching mobile vs. stable students on gender, race/ethnicity, eligibility for free/reduced lunches, and special education status. Analyses showed that mobility was associated with lower performance in the CAPT Writing exam. Follow-up analyses revealed that this trend was only significant among those who were ineligible for free/reduced lunches, but not among eligible students. Additionally, mobile students who were ineligible for free/reduced lunches had lower performance in the CAPT Science exam according to some analyses. Large numbers of students transferring into a school district may adversely affect standardized test performance. This is especially relevant for policies that affect student mobility in schools, given the accountability measures in the No Child Left Behind that are currently being re-considered in the recent Every Student Succeeds Act. PMID:27486427

  15. Inventory of radionuclides for the Great Lakes

    SciTech Connect

    1997-12-31

    This report uses a material balance approach to describe the quantities and composition of reported releases of radionuclides to air and water, and the distribution of these nuclides in atmospheric, aquatic, and biotic compartments of the Great Lakes ecosystem. The primary sources considered are discharges from nuclear fuel cycle facilities in the Great Lakes Basin. Other sources include commercial, industrial, medical, and research institutions. Radionuclide inventories are first presented by source, both natural and anthropogenic, then by geographical and environmental distribution. The concluding section discusses the adequacy of radionuclide monitoring, the need for a reassessment of environmental monitoring of nuclear facilities, radionuclide data reporting, harmonization of monitoring and data reporting, biological transfer factors for lake systems, and radionuclides of concern. A glossary is included.

  16. Detecting low levels of radionuclides in fluids

    DOEpatents

    Patch, Keith D.; Morgan, Dean T.

    2000-01-01

    An apparatus and method for detecting low levels of one or more radionuclides in a fluid sample uses a substrate that includes an ion exchange resin or other sorbent material to collect the radionuclides. A collecting apparatus includes a collecting chamber that exposes the substrate to a measured amount of the fluid sample such that radionuclides in the fluid sample are collected by the ion exchange resin. A drying apparatus, which can include a drying chamber, then dries the substrate. A measuring apparatus measures emissions from radionuclides collected on the substrate. The substrate is positioned in a measuring chamber proximate to a detector, which provides a signal in response to emissions from the radionuclides. Other analysis methods can be used to detect non-radioactive analytes, which can be collected with other types of sorbent materials.

  17. Radionuclide air emission report for the Hanford Site Calendar Year 1993

    SciTech Connect

    Diediker, L.P.; Curn, B.L.; Rhoads, K.; Damberg, E.G.; Soldat, J.K.; Jette, S.J.

    1994-08-01

    This report documents radionuclide air emissions from the Hanford Site in 1993 and the resulting effective dose equivalent to any member of the public. The report has been prepared and will be submitted in accordance with reporting requirements in the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, {open_quotes}National Emissions Standards for Hazardous Air Pollutants,{close_quotes} Subpart H, {open_quotes}National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.{close_quotes}

  18. Transverse section radionuclide scanning system

    DOEpatents

    Kuhl, David E.; Edwards, Roy Q.

    1976-01-01

    This invention provides a transverse section radionuclide scanning system for high-sensitivity quantification of brain radioactivity in cross-section picture format in order to permit accurate assessment of regional brain function localized in three-dimensions. High sensitivity crucially depends on overcoming the heretofore known raster type scanning, which requires back and forth detector movement involving dead-time or partial enclosure of the scan field. Accordingly, this invention provides a detector array having no back and forth movement by interlaced detectors that enclose the scan field and rotate as an integral unit around one axis of rotation in a slip ring that continuously transmits the detector data by means of laser emitting diodes, with the advantages that increased amounts of data can be continuously collected, processed and displayed with increased sensitivity according to a suitable computer program.

  19. Radionuclides in surface and groundwater

    USGS Publications Warehouse

    Campbell, Kate M.

    2009-01-01

    Unique among all the contaminants that adversely affect surface and water quality, radioactive compounds pose a double threat from both toxicity and damaging radiation. The extreme energy potential of many of these materials makes them both useful and toxic. The unique properties of radioactive materials make them invaluable for medical, weapons, and energy applications. However, mining, production, use, and disposal of these compounds provide potential pathways for their release into the environment, posing a risk to both humans and wildlife. This chapter discusses the sources, uses, and regulation of radioactive compounds in the United States, biogeochemical processes that control mobility in the environment, examples of radionuclide contamination, and current work related to contaminated site remediation.

  20. Cosmogenic radionuclides in stone meteorites

    NASA Technical Reports Server (NTRS)

    Cressy, P. J., Jr.

    1976-01-01

    This document presents the techniques and compilation of results of cosmogenic Al-26 measurements at Goddard Space Flight Center on 91 samples of 76 stone meteorites. Short-lived radionuclides, including Na-22, Sc-46, Mn-54, and Co-60, were measured in 13 of these meteorites. About one-third of these data has not previously been published. The results are discussed briefly in terms of (1) depletion of Al-26 and natural potassium due to weathering, (2) possible exposure of several chondrites to an unusually high cosmic-ray flux, (3) comparison of Al-26, Na-22, Sc-46, and Mn5-54 in chondrites with the spallation Ne-22/Ne-21 ratio as a shielding indicator, and (4) comparison of (Al-26)-(Ne-22)/Ne-21 data for achondrite classes with the chondrite trend.

  1. Targeted Radionuclide Therapy of Melanoma.

    PubMed

    Norain, Abdullah; Dadachova, Ekaterina

    2016-05-01

    An estimated 60,000 individuals in the United States and 132,000 worldwide are yearly diagnosed with melanoma. Until recently, treatment options for patients with stages III-IV metastatic disease were limited and offered marginal, if any, improvement in overall survival. The situation changed with the introduction of B-RAF inhibitors and anti-cytotoxic T-lymphocyte antigen 4 and anti-programmed cell death protein 1 immunotherapies into the clinical practice. With only some patients responding well to the immune therapies and with very serious side effects and high costs of immunotherapy, there is still room for other approaches for the treatment of metastatic melanoma. Targeted radionuclide therapy of melanoma could be divided into the domains of radioimmunotherapy (RIT), radiolabeled peptides, and radiolabeled small molecules. RIT of melanoma is currently experiencing a renaissance with the clinical trials of alpha-emitter (213)Bi-labeled and beta-emitter (188)Rhenium-labeled monoclonal antibodies in patients with metastatic melanoma producing encouraging results. The investigation of the mechanism of efficacy of melanoma RIT points at killing of melanoma stem cells by RIT and involvement of immune system such as complement-dependent cytotoxicity. The domain of radiolabeled peptides for targeted melanoma therapy has been preclinical so far, with work concentrated on radiolabeled peptide analogues of melanocyte-stimulating hormone receptor and on melanin-binding peptides. The field of radiolabeled small molecule produced radioiodinated benzamides that cross the cellular membrane and bind to the intracellular melanin. The recent clinical trial demonstrated measurable antitumor effects and no acute or midterm toxicities. We are hopeful that the targeted radionuclide therapy of metastatic melanoma would become a clinical reality as a stand-alone therapy or in combination with the immunotherapies such as anti-PD1 programmed cell death protein 1 monoclonal antibodies

  2. Oversight Hearings on the Report of the National Council on Education Standards and Testing. Hearings before the Subcommittee on Elementary, Secondary, and Vocational Education of the Committee on Education and Labor. House of Representatives, One Hundred Second Congress, Second Session (February 4, 19, and March 18, 1992).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Subcommittee on Elementary, Secondary, and Vocational Education.

    The Subcommittee on Elementary, Secondary, and Vocational Education of the House Committee on Education and Labor met to consider the recommendations of the National Council on Education Standards and Testing. The report recommends the establishment of national education standards, a national system of assessments, and the establishment of a…

  3. GEPNETs update: Radionuclide therapy in neuroendocrine tumors.

    PubMed

    van der Zwan, Wouter A; Bodei, Lisa; Mueller-Brand, Jan; de Herder, Wouter W; Kvols, Larry K; Kwekkeboom, Dik J

    2015-01-01

    Peptide receptor radionuclide therapy (PRRT) is a promising new treatment modality for inoperable or metastasized gastroenteropancreatic neuroendocrine tumors (GEPNETs) patients. Most studies report objective response rates in 15-35% of patients. Also, outcome in terms of progression free survival (PFS) and overall survival compares very favorably with that for somatostatin analogs, chemotherapy, or new, 'targeted' therapies. They also compare favorably to PFS data for liver-directed therapies. Two decades after the introduction of PRRT, there is a growing need for randomized controlled trials comparing PRRT to 'standard' treatment, that is treatment with agents that have proven benefit when tested in randomized trials. Combining PRRT with liver-directed therapies or with targeted therapies could improve treatment results. The question to be answered, however, is whether a combination of therapies performed within a limited time-span from one another results in a better PFS than a strategy in which other therapies are reserved until after (renewed) tumor progression. Randomized clinical trials comparing PRRT with other treatment modalities should be undertaken to determine the best treatment options and treatment sequelae for patients with GEPNETs.

  4. Disposal of BRC wastes containing short-lived radionuclides

    SciTech Connect

    Rogers, V.C.; Baird, R.D.

    1986-01-01

    As part of its responsibility for the safe disposal of low-level (radioactive) waste (LLW), the Texas Low-Level Radioactive Waste Disposal Authority sponsored an analysis of the use of permitted sanitary landfills for the disposal of wastes containing only low concentrations of radionuclides with half-lives of <300 days. Analyses have been performed giving limits on concentrations and total curies annually disposed for 56 short-lived radionuclides. The Low-Level Radioactive Waste Policy Amendments Act, enacted in December 1985, has directed the US Nuclear Regulatory Commission (NRC) to develop standards and procedures for considering and acting on petitions for below regulatory concern (BRC) radioactive waste disposal within 6 months. The NRC has developed a de minimis biomedical waste disposal rule for H-3 and C-14 that places limits on concentrations that can be disposed of without regard to radioactivity. Likewise, the US Environmental Protection Agency (EPA) is developing a regulation for the disposal of BRC radioactive wastes in a sanitary landfill as part of their LLW disposal rulemaking. The purpose of this study is to: 1) conduct multipathway risk assessments using the same methodology that is being used by the EPA for the technical support of their BRC rulemaking; 2) obtain radionuclide concentration and annual total curie limits from the results of the risk assessments by limiting the health impacts to guideline values used in this analysis; and 3) present other restrictions or conditions that emerge from the analysis.

  5. Radionuclide inventory for the Waste Isolation Pilot Plant

    SciTech Connect

    Not Available

    1991-12-31

    This report updates the information previously submitted in the draft report DOE/WIPP 88-005, Radionuclide Source Term for the WIPP, dated 1987 (reference 1). The information in this report provides the projected radionuclide inventory at the WIPP based on the projected waste receipts through the year 2013. The information is based on the 1991 TRU Program Data submittals for the Integrated Data Base (DOE/RW-0006, Rev. 7) from each of the DOE sites generating or storing TRU waste for shipment to the WIPP. The data is based on existing characterization data on the waste in interim storage, waste estimates based on projected programs during the 1991 through 2013 time period, projected treatment processes required to meet WIPP Waste Acceptance Criteria (WAC), and a projection of the waste that will be declared low level waste when it is assayed as part of the certification program for waste shipments to WIPP. This data will serve as a standard reference for WIPP programs requiring radionuclide data, including safety programs, performance assessment, and regulatory compliance. These projections will continue to be periodically updated as the waste data estimates are refined by the generator sites as they participate in the annual update of the Integrated Data Base (IDB).

  6. Standards for Agricultural Occupations Programs in Illinois Community Colleges. Interim Report of the Community College Phase [Phase I] of Project RD1-A8-564 Entitled "Standards for Illinois ABAO Post-Secondary Programs and Secondary Programs in Cook County".

    ERIC Educational Resources Information Center

    Walker, Robert W.; Hemp, Paul E.

    A study was made of Phase 1 of the long-term standards program for agricultural occupations programs for Illinois community colleges. The unique feature of this project was the procedure used to maximize the input of community college teachers in the validation and revision of the national standards. Survey instruments were sent to community…

  7. Conus Medullaris Syndrome following Radionuclide Cisternography.

    PubMed

    Choi, Jay Chol

    2014-01-01

    Radionuclide cisternography is generally considered to be a safe procedure without significant neurological complications. However, in this report we present a patient who developed conus medullaris syndrome following radionuclide cisternography. A 46-year-old woman underwent lumbar puncture followed by radionuclide cisternography with the diagnosis of hydrocephalus. After the cisternography, she developed voiding difficulty with perineal sensory loss. Lumbar MRI revealed a high signal intensity lesion on T2-weighted images at the level of conus medullaris. Considering its clinical course and MRI findings, a spinal cord infarction is highly suggested as a cause of the conus medullaris lesion in this patient.

  8. Nuclear Melt Glass Dissolution and Secondary Mineral Precipitation at 40 to 200C

    SciTech Connect

    Zavarin, M; Roberts, S; Viani, B; Pawloski, G; Rose, T

    2004-06-14

    Most long-lived radionuclides associated with an underground nuclear test are initially incorporated into melt glass and become part of the hydrologic source term (HST) only upon their release via glass dissolution (Pawloski et al., 2001). As the melt glass dissolves, secondary minerals precipitate. The types of secondary minerals that precipitate influence the water chemistry in and around the melt glass. The secondary minerals also provide a sorption sink to the released radionuclides. The changing water chemistry affects the rate of glass dissolution; it also affects the sorption behavior of the released radionuclides. This complex nature of glass dissolution and its important role in defining the HST requires a thorough understanding of glass dissolution and secondary mineral precipitation. The identity of secondary minerals formed at temperatures from 40 to 200 C are evaluated in this report to assist in that understanding.

  9. Radiochemical separation of zirconium and hafnium from other radionuclides.

    PubMed

    Hahn, R B

    1972-11-01

    Radiozirconium and radiohafnium may be separated from all other radionuclides except scandium and protactinium by precipitation with mandelic acid from 5-10 M hydrochloric acid, using commercial zirconyl chloride as carrier. Scandium and protactinium are removed by dissolving the precipitate in sodium carbonate, then adding barium nitrate to precipitate barium carbonate which acts as a scavenger. Zirconium mandelate is finally reprecipitated and the sample weighed and counted in this form. The method was checked by analysing commercial zirconyl chloride and standard rock samples for zirconium and hafnium by neutron-activation analysis.

  10. Radiochemical separation of zirconium and hafnium from other radionuclides.

    PubMed

    Hahn, R B

    1972-11-01

    Radiozirconium and radiohafnium may be separated from all other radionuclides except scandium and protactinium by precipitation with mandelic acid from 5-10 M hydrochloric acid, using commercial zirconyl chloride as carrier. Scandium and protactinium are removed by dissolving the precipitate in sodium carbonate, then adding barium nitrate to precipitate barium carbonate which acts as a scavenger. Zirconium mandelate is finally reprecipitated and the sample weighed and counted in this form. The method was checked by analysing commercial zirconyl chloride and standard rock samples for zirconium and hafnium by neutron-activation analysis. PMID:18961201

  11. [Secondary dyslipidemias].

    PubMed

    Vargová, V; Pytliak, M; Mechírová, V

    2012-03-01

    Dyslipidemias rank among the most important preventabile factors of atherogenesis and its progression. This topic is increasingly being discussed as e.g. more than 50% of Slovak population die on atherosclerotic complications. According to etiology we distinguish primary dyslipidemias with strictly genetic background and secondary ones with origin in other disease or pathological state. Secondary dyslipidemias accompany various diseases, from common (endocrinopathies, renal diseases etc) to rare ones (thesaurismosis etc.) and represents one of symptoms of these diseases. Apart from particular clinical follow up of diagnosed dysipidemias, basic screening and secondary causes as well as treatment due to updated guidelines is recuired. In this review we present the most frequent dyslipidemias of clinical practice.

  12. Tracing Fukushima Radionuclides in the Northern Hemisphere -An Overview

    NASA Astrophysics Data System (ADS)

    Thakur, Punam; Ballard, Sally; Nelson, Roger

    2013-04-01

    hemisphere. Although the releases from the Fukushima NPP were pronounced, due to significant dilution of the radioactivity in the atmosphere as it was transported across the globe, the concentrations of radionuclides measured outside Japan were extremely low. The activities of I-131, Cs-134, and Cs-137 in air were estimated to have diluted by a factor of 105 to 108 during trans-Pacific transport. This paper will present a compilation of the radionuclide concentrations measured across the northern hemisphere by various national and international monitoring networks. It will focus on the most prevalent cesium and iodine isotopes, but other secondary isotopes will be discussed. Spatial and Temporal patterns and differences will be contrasted. The effects from this global radionuclide dispersal are reported and discussed. The activity ratios of ^131I/^137Cs and ^134Cs/^137Cs measured at several locations are evaluated to gain an insight into the fuel burn-up, the inventory of radionuclides in the reactor and thus on the isotopic signature of the accident. It is important to note that all of the radiation levels detected across the northern hemisphere have been very low and are well below any level of public and environmental concern.

  13. Radionuclide angiography for assessment of hyperthyroidism

    SciTech Connect

    Lee, V.W.; Welji, A.N.; Shapiro, J.H.; Angtuaco, E.

    1982-01-01

    A retrospective study of 66 radionuclide angiograms of the thyroid showed that a simple visual inspection of the images is highly accurate for diagnosing hyperthyroidism. Mathematical analysis with computers is not necessary.

  14. Radionuclide carriers for targeting of cancer

    PubMed Central

    Sofou, Stavroula

    2008-01-01

    This review describes strategies for the delivery of therapeutic radionuclides to tumor sites. Therapeutic approaches are summarized in terms of tumor location in the body, and tumor morphology. These determine the radionuclides of choice for suggested targeting ligands, and the type of delivery carriers. This review is not exhaustive in examples of radionuclide carriers for targeted cancer therapy. Our purpose is two-fold: to give an integrated picture of the general strategies and molecular constructs currently explored for the delivery of therapeutic radionuclides, and to identify challenges that need to be addressed. Internal radiotherapies for targeting of cancer are at a very exciting and creative stage. It is expected that the current emphasis on multidisciplinary approaches for exploring such therapeutic directions should enable internal radiotherapy to reach its full potential. PMID:18686778

  15. System and method for assaying a radionuclide

    SciTech Connect

    Cadieux, James R; King, III, George S; Fugate, Glenn A

    2014-12-23

    A system for assaying a radionuclide includes a liquid scintillation detector, an analyzer connected to the liquid scintillation detector, and a delay circuit connected to the analyzer. A gamma detector and a multi-channel analyzer are connected to the delay circuit and the gamma detector. The multi-channel analyzer produces a signal reflective of the radionuclide in the sample. A method for assaying a radionuclide includes selecting a sample, detecting alpha or beta emissions from the sample with a liquid scintillation detector, producing a first signal reflective of the alpha or beta emissions, and delaying the first signal a predetermined time. The method further includes detecting gamma emissions from the sample, producing a second signal reflective of the gamma emissions, and combining the delayed first signal with the second signal to produce a third signal reflective of the radionuclide.

  16. Dosimetry and Case Studies for Selected Radionuclides

    SciTech Connect

    Leggett, Richard Wayne

    2009-01-01

    This is a comprehensive review and analysis of biokinetic and dosimetric information for those radionuclides most likely to be involved in accidental exposures to workers or members of the public or used in radiological terrorism.

  17. Long lived gamma emitting radionuclides in incense.

    PubMed

    Alrefae, Tareq

    2013-10-01

    A study of long-lived gamma emitters in incense was performed. The incense samples originated from seven different countries, and the investigated radionuclides were Ra, Ra, and K. Gamma spectroscopy revealed the presence of all three investigated radionuclides in all samples. Interestingly, the activity concentrations revealed a clear bimodal distribution that distinguished samples that were natural incense from others that were processed incense. The activity concentrations in the latter group were found to be one order of magnitude greater than in the former group. Consequently, the estimated annual effective dose from the latter group was one order of magnitude higher than that of the former group. Nonetheless, the doses from both groups were found to be some three orders of magnitude less than the average worldwide exposure to inhaled natural radionuclides. This finding suggests the radiological safety of incense for the investigated radionuclides.

  18. Radionuclide scintigraphy of bacterial nephritis

    SciTech Connect

    Conway, J.J.; Weiss, S.C.; Shkolnik, A.; Yogev, R.; Firlit, C.; Traisman, E.S.

    1984-01-01

    Pyelonephritis is a leading cause of renal failure and is expected to cost as much as three billion dollars in 1984. The diagnosis of urinary tract infection is usually not difficult. However, localization of the infection within the renal parenchyma as opposed to the collecting system is much more difficult. Flank pain, fever, bacteiuria and evidence of parenchymal involvement by intravenous urography may be absent or unrecognized particularly in the infant. Ultrasound and Nuclear Medicine are advocated as better methods to define parenchymal involvement. Such definition is important in the consideration of treatment since parenchymal involvement of the kidney carries a much more ominous potential outcome than infection restricted to within the collecting system. 38 children with a clinical diagnosis of urinary tract infection were studied. 26 of the patients demonstrated abnormal renal parenchymal findings with Gallium-67 Citrate or Tc-99m Glucoheptonate scintigraphy. Intravenous urography was notably ineffective with only 5 of the 20 interpreted as abnormal due to parenchymal disease or decreased function. 11 were entirely normal while only 5 demonstrated scars or hydronephrosis. Only 10 of 17 patients demonstrated intranvesicoureteral reflux on x-ray or nuclear cystography. Ultrasound depicted 6 of 20 patients as having parenchymal abnormalities. Seven were normal. Nonspecific findings such as dilitation of the renal pelvis or renal enlargement was noted in 11 of the 20 patients. Radionuclide Scintigraphy is the most efficacious modality to detect since acute bacterial nephritis.

  19. Radionuclides in an underground environment

    SciTech Connect

    Thompson, J.L.

    1996-08-01

    In the 100 years since Becquerel recognized radioactivity, mankind has been very successful in producing large amounts of radioactive materials. We have been less successful in reaching a consensus on how to dispose of the billions of curies of fission products and transuranics resulting from nuclear weapons testing, electrical power generation, medical research, and a variety of other human endeavors. Many countries, including the United States, favor underground burial as a means of disposing of radioactive wastes. There are, however, serious questions about how such buried wastes may behave in the underground environment and particularly how they might eventually contaminate water, air and soil resources on which we are dependent. This paper describes research done in the United States in the state of Nevada on the behavior of radioactive materials placed underground. During the last thirty years, a series of ``experiments`` conducted for other purposes (testing of nuclear weapons) have resulted in a wide variety of fission products and actinides being injected in rock strata both above and below the water table. Variables which seem to control the movement of these radionuclides include the physical form (occlusion versus surface deposition), the chemical oxidation state, sorption by mineral phases of the host rock, and the hydrologic properties of the medium. The information gained from these studies should be relevant to planning for remediation of nuclear facilities elsewhere in the world and for long-term storage of nuclear wastes.

  20. Biodecontamination of radionuclide contaminated concrete

    SciTech Connect

    Hamilton, M.A.; Rogers, R.D.; Benson, J.

    1996-10-01

    Within the nuclear industry, there are literally hundreds of square miles of radionuclide contaminated concrete surfaces. A novel technology for biologically decontaminating concrete is being developed. The technology exploits a naturally occurring phenomenon referred to as microbially influenced degradation (MID) in which bacteria produce acids that dissolve the cement matrix of the concrete. Accelerated testing in laboratory conditions was conducted. The bacteria Thiobacillus thiooxidans, supplied from a continuous flow bioreactor, was applied to an exposed concrete surface. A control chamber exposing concrete to sterile media was operated under the same conditions. One hundred percent of surrogate cobalt contamination was recovered from the Thiobacillus treated concrete and 1 mm thickness of concrete material was removed in 60 days. Prototype chambers that can be mounted directly to concrete surfaces have been designed to allow control of environmental conditions to promote MID after inoculation of the surface with bacteria. Studies to determine optimum source and quantity of reduced sulfur, bacterial species or consortia best suited for rapid MID, and methods of application and delivery of bacteria and nutrients will be discussed.

  1. Treatment of radionuclide contaminated soils

    SciTech Connect

    Pettis, S.A.; Kallas, A.J.; Kochen, R.L.; McGlochlin, S.C.

    1988-06-01

    Rockwell, International, Rocky Flats Plants, is committed to remediating within the scope of RCRA/CERCLA, Solid Waste Managements Units (SWMUs) at Rocky Flats found to be contaminated with hazardous substances. SWMUs fund to have radionuclide (uranium, plutonium, and/or americium) concentrations in the soils and/or groundwater that exceed background levels or regulatory limits will also be included in this remediation effort. This paper briefly summarizes past and present efforts by Rockwell International, Rocky Flats Plant, to identify treatment technologies appropriate for remediating actinide contaminated soils. Many of the promising soil treatments evaluated in Rocky Flats' laboratories during the late 1970's and early 1980's are currently being revisited. These technologies are generally directed toward substantially reducing the volume of contaminated soils, with the subsequent intention of disposing of a small remaining concentrated fraction of contaminated soil in a facility approved to receive radioactive wastes. Treatment processes currently will be treated to remove actinides, and recycled back to the process. Past investigations have included evaluations of dry screening, wet screening, scrubbing, ultrasonics, chemical oxidation, calcination, desliming, flotation, and heavy-liquid density separation. 8 refs., 2 figs.

  2. Solubility limits on radionuclide dissolution

    SciTech Connect

    Kerrisk, J.F.

    1984-12-31

    This paper examines the effects of solubility in limiting dissolution rates of a number of important radionuclides from spent fuel and high-level waste. Two simple dissolution models were used for calculations that would be characteristics of a Yucca Mountain repository. A saturation-limited dissolution model, in which the water flowing through the repository is assumed to be saturated with each waste element, is very conservative in that it overestimates dissolution rates. A diffusion-limited dissolution model, in which element-dissolution rates are limited by diffusion of waste elements into water flowing past the waste, is more realistic, but it is subject to some uncertainty at this time. Dissolution rates of some elements (Pu, Am, Sn, Th, Zr, Sm) are always limited by solubility. Dissolution rates of other elements (Cs, Tc, Np, Sr, C, I) are never solubility limited; their release would be limited by dissolution of the bulk waste form. Still other elements (U, Cm, Ni, Ra) show solubility-limited dissolution under some conditions. 9 references, 3 tables.

  3. (Radiological assessments of radionuclide releases)

    SciTech Connect

    Hoffman, F.O.

    1990-12-28

    As a consequence of the Chernobyl accident, data have been obtained throughout the Northern Hemisphere on the concentrations of radionuclides in air, vegetation, soil, water, and foodstuffs that could be important means of human exposure. At the IAEA's invitation, the traveler reviewed recently published data and handbook summaries. The traveler evaluated the need for revising the default values recommended in Chapter 5, Terrestrial and Aquatic Food Chain Transport,'' of IAEA Safety Series No. 57. All attempts at revision were made to keep the mathematical complexity of the models to a minimum without substantial underestimation of dose to critical population subgroups. The traveler also served as chairman of the Multiple Pathways Working Group of the Coordinated Research Program on VAMP. This group has been established to test predictions of models assessing multiple exposure pathways potentially leading to human exposure to {sup 137}Cs. Testing is carried out for major components of assessment models that predict deposition, environmental transport, food chain bioaccumulation, and subsequent uptake and retention in the human body and dose due to exposure to external gamma radiation.

  4. Radionuclide evaluation of lung trauma

    SciTech Connect

    Lull, R.J.; Tatum, J.L.; Sugerman, H.J.; Hartshorne, M.F.; Boll, D.A.; Kaplan, K.A.

    1983-07-01

    Nuclear medicine imaging procedures can play a significant role in evaluating the pulmonary complications that are seen in trauma patients. A quantitative method for measuring increased pulmonary capillary permeability that uses Tc-99m HSA allows early diagnosis of acute respiratory distress syndrome (ARDS) and accurately differentiates this condition from pneumonia or cardiogenic pulmonary edema. This technique may be of great value in following the response to therapy. The use of 133Xe to diagnose inhalation injury remains an important diagnostic tool, particularly at hospitals with specialized burn units. Regional decreases in ventilation-perfusion images reliably localize aspirated foreign bodies. Radionuclide techniques that are used to demonstrate gastropulmonary aspiration remain controversial and require further clinical evaluation. Pulmonary perfusion imaging, although nonspecific, may provide the earliest clue for correct diagnosis of fat embolism, air embolism, contusion, or laceration. Furthermore, the possibility of perfusion abnormality due to these uncommon conditions must be remembered whenever trauma patients are evaluated for pulmonary thromboembolism with scintigraphy. Occasionally, liver or spleen scintigraphy may be the most appropriate procedure when penetrating chest trauma also involves these subdiaphragmatic organs.

  5. Alchemy with short-lived radionuclides

    SciTech Connect

    Rubio, F.F.; Finn, R.D.; Gilson, A.J.

    1981-04-01

    A variety of short-lived radionuclides are produced and subsequently incorporated into radiopharmaceutical compounds in the radionuclide production program currently being conducted at the Cyclotron Facility of Mount Sinai Medical Center. The recovery of high specific activity oxygen-15 labelled water prepared by means of an inexpensive system operating in conjunction with an on-line radiogas target routinely utilized for oxygen-15 labelled carbon dioxide studies is currently receiving particular attention.

  6. Secondary Products

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In spite of their name, "secondary" products are essential for plant survival. They are required for basic cell functions as well as communicating the plant's presence to the surrounding environment and defense against pests as defined in the broad sense (i.e., diseases, nematodes, insects and plan...

  7. Risk Due to Radiological Terror Attacks With Natural Radionuclides

    SciTech Connect

    Friedrich, Steinhaeusler; Lyudmila, Zaitseva; Stan, Rydell

    2008-08-07

    The naturally occurring radionuclides radium (Ra-226) and polonium (Po-210) have the potential to be used for criminal acts. Analysis of international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (CSTO), operated at the University of Salzburg, shows that several acts of murder and terrorism with natural radionuclides have already been carried out in Europe and Russia. Five different modes of attack (T) are possible: (1) Covert irradiation of an individual in order to deliver a high individual dose; (2) Covert irradiation of a group of persons delivering a large collective dose; (3) Contamination of food or drink; (4) Generation of radioactive aerosols or solutions; (5) Combination of Ra-226 with conventional explosives (Dirty Bomb).This paper assesses the risk (R) of such criminal acts in terms of: (a) Probability of terrorist motivation deploying a certain attack mode T; (b) Probability of success by the terrorists for the selected attack mode T; (c) Primary damage consequence (C) to the attacked target (activity, dose); (d) Secondary damage consequence (C') to the attacked target (psychological and socio-economic effects); (e) Probability that the consequences (C, C') cannot be brought under control, resulting in a failure to manage successfully the emergency situation due to logistical and/or technical deficits in implementing adequate countermeasures. Extensive computer modelling is used to determine the potential impact of such a criminal attack on directly affected victims and on the environment.

  8. Ventricular dysfunction in children with obstructive sleep apnea: radionuclide assessment

    SciTech Connect

    Tal, A.; Leiberman, A.; Margulis, G.; Sofer, S.

    1988-01-01

    Ventricular function was evaluated using radionuclide ventriculography in 27 children with oropharyngeal obstruction and clinical features of obstructive sleep apnea. Their mean age was 3.5 years (9 months to 7.5 years). Conventional clinical assessment did not detect cardiac involvement in 25 of 27 children; however, reduced right ventricular ejection fraction (less than 35%) was found in 10 (37%) patients (mean: 19.5 +/- 2.3% SE, range: 8-28%). In 18 patients wall motion abnormality was detected. In 11 children in whom radionuclide ventriculography was performed before and after adenotonsillectomy, right ventricular ejection fraction rose from 24.4 +/- 3.6% to 46.7 +/- 3.4% (P less than 0.005), and in all cases wall motion showed a definite improvement. In five children, left ventricular ejection fraction rose greater than 10% after removal of oropharyngeal obstruction. It is concluded that right ventricular function may be compromised in children with obstructive sleep apnea secondary to adenotonsillar hypertrophy, even before clinical signs of cardiac involvement are present.

  9. Risk Due to Radiological Terror Attacks With Natural Radionuclides

    NASA Astrophysics Data System (ADS)

    Friedrich, Steinhäusler; Stan, Rydell; Lyudmila, Zaitseva

    2008-08-01

    The naturally occurring radionuclides radium (Ra-226) and polonium (Po-210) have the potential to be used for criminal acts. Analysis of international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (CSTO), operated at the University of Salzburg, shows that several acts of murder and terrorism with natural radionuclides have already been carried out in Europe and Russia. Five different modes of attack (T) are possible: (1) Covert irradiation of an individual in order to deliver a high individual dose; (2) Covert irradiation of a group of persons delivering a large collective dose; (3) Contamination of food or drink; (4) Generation of radioactive aerosols or solutions; (5) Combination of Ra-226 with conventional explosives (Dirty Bomb). This paper assesses the risk (R) of such criminal acts in terms of: (a) Probability of terrorist motivation deploying a certain attack mode T; (b) Probability of success by the terrorists for the selected attack mode T; (c) Primary damage consequence (C) to the attacked target (activity, dose); (d) Secondary damage consequence (C') to the attacked target (psychological and socio-economic effects); (e) Probability that the consequences (C, C') cannot be brought under control, resulting in a failure to manage successfully the emergency situation due to logistical and/or technical deficits in implementing adequate countermeasures. Extensive computer modelling is used to determine the potential impact of such a criminal attack on directly affected victims and on the environment.

  10. Radionuclide Air Emissions Report for the Hanford Site Calendar Year 1999

    SciTech Connect

    ROKKAN, D.J.

    2000-06-01

    This report documents radionuclide air emissions from the US. Department of Energy (DOE) Hanford Site in 1999 and the resulting effective dose equivalent to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations (CFR). Title 40, Protection of the Environment, Part 61. National Emission Standards for Hazardous Air Pollutants, Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities'', and with the Washington Administrative Code (WAC) Chapter 246-247. Radiation Protection-Air Emissions. The federal regulations in Subpart H of 40 CFR 61 require the measurement and reporting of radionuclides emitted from US. Department of Energy (DOE) facilities and the resulting offsite dose from those emissions. A standard of 10 mrem/yr effective dose equivalent (EDE) is imposed on them. The EDE to the MEI due to routine emissions in 1999 from Hanford Site point sources was 0.029 mrem (2.9 E-04 mSv), which is less than 0.3 percent of the federal standard. WAC 246-247 requires the reporting of radionuclide emissions from all Hanford Site sources, during routine as well as nonroutine operations. The state has adopted the 40 CFR 61 standard of 10 mrem/yr EDE into their regulations. The state further requires that the EDE to the MEI be calculated not only from point source emissions but also from diffuse and fugitive sources of emissions. The EDE from diffuse and fugitive emissions at the Hanford Site in 1999 was 0.039 mrem (3.9 E-04 mSv) EDE. The total dose from point sources and from diffuse and fugitive sources of radionuclide emissions during all operating conditions in 1999 was 0.068 mrem (6.8 E-04 mSv) EDE, which is less than 0.7 percent of the state standard.

  11. Secondary osteoporosis.

    PubMed

    Sheu, Angela; Diamond, Terry

    2016-06-01

    Secondary osteoporosis is less common than primary osteoporosis. It may be suspected in patients who present with a fragility fracture despite having no risk factors for osteoporosis. In addition, secondary osteoporosis should be considered if the bone density Z-score is -2.5 or less. Consider the fracture site and presence of other clinical clues to guide investigations for an underlying cause. The tests to use are those that are indicated for the suspected cause. Baseline investigations include tests for bone and mineral metabolism (calcium, phosphate, alkaline phosphatase, 25-hydroxyvitamin D, parathyroid hormone), liver and kidney function, full blood count and thyroid-stimulating hormone. More detailed testing may be required in patients with severe osteoporosis.

  12. Secondary osteoporosis

    PubMed Central

    Sheu, Angela; Diamond, Terry

    2016-01-01

    SUMMARY Secondary osteoporosis is less common than primary osteoporosis. It may be suspected in patients who present with a fragility fracture despite having no risk factors for osteoporosis. In addition, secondary osteoporosis should be considered if the bone density Z-score is –2.5 or less. Consider the fracture site and presence of other clinical clues to guide investigations for an underlying cause. The tests to use are those that are indicated for the suspected cause. Baseline investigations include tests for bone and mineral metabolism (calcium, phosphate, alkaline phosphatase, 25-hydroxyvitamin D, parathyroid hormone), liver and kidney function, full blood count and thyroid-stimulating hormone. More detailed testing may be required in patients with severe osteoporosis. PMID:27346916

  13. Secondary osteoporosis.

    PubMed

    Sheu, Angela; Diamond, Terry

    2016-06-01

    Secondary osteoporosis is less common than primary osteoporosis. It may be suspected in patients who present with a fragility fracture despite having no risk factors for osteoporosis. In addition, secondary osteoporosis should be considered if the bone density Z-score is -2.5 or less. Consider the fracture site and presence of other clinical clues to guide investigations for an underlying cause. The tests to use are those that are indicated for the suspected cause. Baseline investigations include tests for bone and mineral metabolism (calcium, phosphate, alkaline phosphatase, 25-hydroxyvitamin D, parathyroid hormone), liver and kidney function, full blood count and thyroid-stimulating hormone. More detailed testing may be required in patients with severe osteoporosis. PMID:27346916

  14. Focus & Higher Standards for Secondary Schools.

    ERIC Educational Resources Information Center

    International Baccalaureate North America, Inc., New York, NY.

    The International Baccalaureate (IB) program, in which students in the last 2 years of high school can earn a diploma recognized for university admission throughout the world and for course credit at colleges and universities in Canada and the United States, is described. Information about the program is provided in the following areas: (1)…

  15. U.S. Department of Energy Report, 2005 LANL Radionuclide Air Emissions

    SciTech Connect

    Keith W. Jacobson, David P. Fuehne

    2006-09-01

    Amendments to the Clean Air Act, which added radionuclides to the National Emissions Standards for Hazardous Air Pollutants (NESHAP), went into effect in 1990. Specifically, a subpart (H) of 40 CFR 61 established an annual limit on the impact to the public attributable to emissions of radionuclides from U.S. Department of Energy facilities, such as the Los Alamos National Laboratory (LANL). As part of the new NESHAP regulations, LANL must submit an annual report to the U.S. Environmental Protection Agency headquarters and the regional office in Dallas by June 30. This report includes results of monitoring at LANL and the dose calculations for the calendar year 2006.

  16. Primary calibrations of radionuclide solutions and sources for the EML quality assessment program

    SciTech Connect

    Fisenne, I.M.

    1993-12-31

    The quality assurance procedures established for the operation of the U.S. Department of Energy`s Environmental Measurements Laboratory (DOE-EML`s) Quality Assessment Program (QAP) are essentially the same as those that are in effect for any EML program involving radiometric measurements. All these programs have at their core the use of radionuclide standards for their instrument calibration. This paper focuses on EML`s approach to the acquisition, calibration and application of a wide range of radionuclide sources that are required to meet its programmatic needs.

  17. CASCADER: An m-chain gas-phase radionuclide transport and fate model. Volume 1, Basic physics and mathematics

    SciTech Connect

    Lindstrom, F.T.; Cawlfield, D.E.; Emer, D.F.; Shott, G.J.; Donahue, M.E.

    1992-06-01

    Chemicals and radionuclides move either in the gas-phase, liquid-phase, or both phases in soils. They may be acted upon by either biological or abiotic processes as they are advected and/or dispersed. Furthermore, parent and daughter radionuclides may decay as they are transported in the soil. CASCADER is a gas-phase, one space dimensional transport and fate model for an m-chain of radionuclides in very dry soil. This model contains barometric pressure-induced advection and diffusion together with linear irreversible and linear reversible sorption for each radionuclide. The advocation velocity is derived from an embedded air-pumping submodel. The airpumping submodel is based on an assumption of isothermal conditions and is barometric pressure driven. CASCADER allows the concentration of source radionuclides to decay via the classical Bateman chain of simple, first-order kinetic processes. The transported radionuclides also decay via first-order processes while in the soil. A mass conserving, flux-type inlet and exit set of boundary conditions is used. The user must supply the initial distribution for the parent radionuclide in the soil. The initial daughter distribution is found using equilibrium rules. The model is user friendly as it uses a prompt-driven, free-form input. The code is ANSI standard Fortran 77.

  18. Preparation of Radiopharmaceuticals Labeled with Metal Radionuclides

    SciTech Connect

    Welch, M.J.

    2012-02-16

    The overall goal of this project was to develop methods for the production of metal-based radionuclides, to develop metal-based radiopharmaceuticals and in a limited number of cases, to translate these agents to the clinical situation. Initial work concentrated on the application of the radionuclides of Cu, Cu-60, Cu-61 and Cu-64, as well as application of Ga-68 radiopharmaceuticals. Initially Cu-64 was produced at the Missouri University Research Reactor and experiments carried out at Washington University. A limited number of studies were carried out utilizing Cu-62, a generator produced radionuclide produced by Mallinckrodt Inc. (now Covidien). In these studies, copper-62-labeled pyruvaldehyde Bis(N{sup 4}-methylthiosemicarbazonato)-copper(II) was studied as an agent for cerebral myocardial perfusion. A remote system for the production of this radiopharmaceutical was developed and a limited number of patient studies carried out with this agent. Various other copper radiopharmaceuticals were investigated, these included copper labeled blood imaging agents as well as Cu-64 labeled antibodies. Cu-64 labeled antibodies targeting colon cancer were translated to the human situation. Cu-64 was also used to label peptides (Cu-64 octriatide) and this is one of the first applications of a peptide radiolabeled with a positron emitting metal radionuclide. Investigations were then pursued on the preparation of the copper radionuclides on a small biomedical cyclotron. A system for the production of high specific activity Cu-64 was developed and initially the Cu-64 was utilized to study the hypoxic imaging agent Cu-64 ATSM. Utilizing the same target system, other positron emitting metal radionuclides were produced, these were Y-86 and Ga-66. Radiopharmaceuticals were labeled utilizing both of these radionuclides. Many studies were carried out in animal models on the uptake of Cu-ATSM in hypoxic tissue. The hypothesis is that Cu-ATSM retention in vivo is dependent upon the

  19. Fast analysis of radionuclide decay chain migration

    NASA Astrophysics Data System (ADS)

    Chen, J. S.; Liang, C. P.; Liu, C. W.; Li, L.

    2014-12-01

    A novel tool for rapidly predicting the long-term plume behavior of an arbitrary length radionuclide decay chain is presented in this study. This fast tool is achieved based on generalized analytical solutions in compact format derived for a set of two-dimensional advection-dispersion equations coupled with sequential first-order decay reactions in groundwater system. The performance of the developed tool is evaluated by a numerical model using a Laplace transform finite difference scheme. The results of performance evaluation indicate that the developed model is robust and accurate. The developed model is then used to fast understand the transport behavior of a four-member radionuclide decay chain. Results show that the plume extents and concentration levels of any target radionuclide are very sensitive to longitudinal, transverse dispersion, decay rate constant and retardation factor. The developed model are useful tools for rapidly assessing the ecological and environmental impact of the accidental radionuclide releases such as the Fukushima nuclear disaster where multiple radionuclides leaked through the reactor, subsequently contaminating the local groundwater and ocean seawater in the vicinity of the nuclear plant.

  20. Radionuclide Retention in Concrete Waste Forms

    SciTech Connect

    Mattigod, Shas V.; Bovaird, Chase C.; Wellman, Dawn M.; Wood, Marcus I.

    2010-09-30

    Assessing long-term performance of Category 3 waste cement grouts for radionuclide encasement requires knowledge of the radionuclide-cement interactions and mechanisms of retention (i.e., sorption or precipitation); the mechanism of contaminant release; the significance of contaminant release pathways; how waste form performance is affected by the full range of environmental conditions within the disposal facility; the process of waste form aging under conditions that are representative of processes occurring in response to changing environmental conditions within the disposal facility; the effect of waste form aging on chemical, physical, and radiological properties; and the associated impact on contaminant release. This knowledge will enable accurate prediction of radionuclide fate when the waste forms come in contact with groundwater. The information presented in the report provides data that 1) quantify radionuclide retention within concrete waste form materials similar to those used to encapsulate waste in the Low-Level Waste Burial Grounds (LLBG); 2) measure the effect of concrete waste form properties likely to influence radionuclide migration; and 3) quantify the stability of uranium-bearing solid phases of limited solubility in concrete.

  1. Radionuclide Retention in Concrete Wasteforms - FY13

    SciTech Connect

    Snyder, Michelle MV; Golovich, Elizabeth C.; Wellman, Dawn M.; Crum, Jarrod V.; Lapierre, Robert; Dage, Denomy C.; Parker, Kent E.; Cordova, Elsa A.

    2013-10-15

    Assessing long-term performance of Category 3 waste cement grouts for radionuclide encasement requires knowledge of the radionuclide-cement interactions and mechanisms of retention (i.e., sorption or precipitation); the mechanism of contaminant release; the significance of contaminant release pathways; how wasteform performance is affected by the full range of environmental conditions within the disposal facility; the process of wasteform aging under conditions that are representative of processes occurring in response to changing environmental conditions within the disposal facility; the effect of wasteform aging on chemical, physical, and radiological properties; and the associated impact on contaminant release. This knowledge will enable accurate prediction of radionuclide fate when the wasteforms come in contact with groundwater. Data collected throughout the course of this work will be used to quantify the efficacy of concrete wasteforms, similar to those used in the disposal of low-level waste and mixed low-level waste, for the immobilization of key radionuclides (i.e., uranium, technetium, and iodine). Data collected will also be used to quantify the physical and chemical properties of the concrete affecting radionuclide retention.

  2. Radionuclide Mobility at the Nevada Test Site

    SciTech Connect

    Hu, Q; Smith, D; Rose, T; Glascoe, L; Steefel, C; Zavarin, M

    2003-11-13

    Underground nuclear tests conducted at the Nevada Test Site (NTS) are characterized by abundant fission product and actinide source terms. Included are {sup 99}Tc and other soluble radionuclides ({sup 3}H, {sup 14}C, {sup 36}Cl, {sup 85}Kr, and {sup 129}I), which are presumably mobile in groundwater and potentially toxic to down-gradient receptors. NTS provides the Office of Civilian Radioactive Waste Management (OCRWM) with an analog of the release of these radionuclides from a nuclear waste repository in the absence of engineered barriers. The investigation described in this report synthesizes a substantial body of data collected on the identity and distribution of soluble radionuclides at field scales over distances of hundreds of meters, for durations up to 40 years, and under hydrogeologic conditions very similar to the proposed geological repository at Yucca Mountain. This body of data is complemented by laboratory transport studies and a synthesis of recent modeling investigations from the NTS, with an emphasis on the ongoing Yucca Mountain Program (YMP) efforts. Overall, understanding the controls of radionuclide mobility associated with these nuclear tests will provide insight into the repository's future performance as well as bounds and calibrations for the numerical predictions of long-term radionuclide releases and migration.

  3. Idaho radionuclide exposure study: Literature review

    SciTech Connect

    Baker, E.G.; Freeman, H.D.; Hartley, J.N.

    1987-10-01

    Phosphate ores contain elevated levels of natural radioactivity, some of which is released to the environment during processing or use of solid byproducts. The effect of radionuclides from Idaho phosphate processing operations on the local communities has been the subject of much research and study. The literature is reviewed in this report. Two primary radionuclide pathways to the environment have been studied in detail: (1) airborne release of volatile radionuclides, primarily /sup 210/Po, from calciner stacks at the two elemental phosphorus plants; and (2) use of byproduct slag as an aggregate for construction in Soda Springs and Pocatello. Despite the research, there is still no clear understanding of the population dose from radionuclide emissions, effluents, and solid wastes from phosphate processing plants. Two other potential radionuclide pathways to the environment have been identified: radon exhalation from phosphogypsum and ore piles and contamination of surface and ground waters. Recommendations on further study needed to develop a data base for a complete risk assssment are given in the report.

  4. Pacific Northwest National Laboratory Facility Radionuclide Emission Points and Sampling Systems

    SciTech Connect

    Barfuss, Brad C.; Barnett, J. Matthew; Ballinger, Marcel Y.

    2009-04-08

    Battelle—Pacific Northwest Division operates numerous research and development laboratories in Richland, Washington, including those associated with the Pacific Northwest National Laboratory (PNNL) on the Department of Energy’s Hanford Site that have the potential for radionuclide air emissions. The National Emission Standard for Hazardous Air Pollutants (NESHAP 40 CFR 61, Subparts H and I) requires an assessment of all effluent release points that have the potential for radionuclide emissions. Potential emissions are assessed annually. Sampling, monitoring, and other regulatory compliance requirements are designated based upon the potential-to-emit dose criteria found in the regulations. The purpose of this document is to describe the facility radionuclide air emission sampling program and provide current and historical facility emission point system performance, operation, and design information. A description of the buildings, exhaust points, control technologies, and sample extraction details is provided for each registered or deregistered facility emission point. Additionally, applicable stack sampler configuration drawings, figures, and photographs are provided.

  5. Radionuclide imaging of abomasal emptying in sheep.

    PubMed

    Nicholson, T; Stockdale, H R; Critchley, M; Grime, J S; Jones, R S; Maltby, P

    1997-01-01

    A liquid radionuclide tracer was administered to nine sheep in order to visualise the abomasum with a gamma camera computer system. The aim was to develop a method of studying gastric emptying, with minimal surgical intervention. Oral administration of the tracer gave good images of the whole complex stomach, but quantifying abomasal emptying was not possible because of the superimposition of the stomach compartments. When the reticular groove reflex was stimulated with oral copper sulphate the radionuclide bypassed the reticulorumen, allowing quantitative analysis of abomasal activity. However, the repeatability of the reflex activation was low. Radionuclide administered directly into the abomasum produced good images of abomasal outflow and provided digital data which were analysed quantitatively. A wide range of emptying rates was observed, generally with a stepped pattern.

  6. State of radionuclides in natural waters

    SciTech Connect

    Kulmatov, R.A.; Rakhmatov, U.; Kist, A.A.; Volkov, A.A.

    1987-03-01

    This work is devoted to a study of the kinetics of attainment of equilibrium between various forms of the radionuclide mercury-203 and to an evaluation of the part played by isotope exchange in this process. The radionuclide mercury-203 was added without a carrier to natural waters of the Syr-Dar'ya and Amu-Dar'ya Rivers and the Aral Sea in the cationic form (3). In order to determine the time of attainment of equilibrium between the forms of the radionuclide mercury-203 and the stable nuclide analogs, they used the methods of sorption on L-36 glass, AV-17 anion-exchanger, KU-2 cation-exchanger, extraction with chloroform plus isobutyl alcohol, and filtration.

  7. Radioimmunotherapy with alpha-particle emitting radionuclides.

    PubMed

    Zalutsky, M R; Pozzi, O R

    2004-12-01

    An important consideration in the development of effective strategies for radioimmunotherapy is the nature of the radiation emitted by the radionuclide. Radionuclides decaying by the emission of alpha-particles offer the possibility of matching the cell specific reactivity of monoclonal antibodies with radiation with a range of only a few cell diameters. Furthermore, alpha-particles have important biological advantages compared with external beam radiation and beta-particles including a higher biological effectiveness, which is nearly independent of oxygen concentration, dose rate and cell cycle position. In this review, the clinical settings most likely to benefit from alpha-particle radioimmunotherapy will be discussed. The current status of preclinical and clinical research with antibodies labeled with 3 promising alpha-particle emitting radionuclides - (213)Bi, (225)Ac, and (211)At - also will be summarized.

  8. Radioimmunotherapy with alpha-particle emitting radionuclides.

    PubMed

    Zalutsky, M R; Pozzi, O R

    2004-12-01

    An important consideration in the development of effective strategies for radioimmunotherapy is the nature of the radiation emitted by the radionuclide. Radionuclides decaying by the emission of alpha-particles offer the possibility of matching the cell specific reactivity of monoclonal antibodies with radiation with a range of only a few cell diameters. Furthermore, alpha-particles have important biological advantages compared with external beam radiation and beta-particles including a higher biological effectiveness, which is nearly independent of oxygen concentration, dose rate and cell cycle position. In this review, the clinical settings most likely to benefit from alpha-particle radioimmunotherapy will be discussed. The current status of preclinical and clinical research with antibodies labeled with 3 promising alpha-particle emitting radionuclides - (213)Bi, (225)Ac, and (211)At - also will be summarized. PMID:15640792

  9. Diffusion of Radionuclides in Concrete and Soil

    SciTech Connect

    Mattigod, Shas V.; Wellman, Dawn M.; Bovaird, Chase C.; Parker, Kent E.; Recknagle, Kurtis P.; Clayton, Libby N.; Wood, Marcus I.

    2012-04-25

    One of the methods being considered for safely disposing of Category 3 low-level radioactive wastes is to encase the waste in concrete. Such concrete encasement would contain and isolate the waste packages from the hydrologic environment and would act as an intrusion barrier. Any failure of concrete encasement may result in water intrusion and consequent mobilization of radionuclides from the waste packages. The mobilized radionuclides may escape from the encased concrete by mass flow and/or diffusion and move into the surrounding subsurface environment. Therefore, it is necessary to assess the performance of the concrete encasement structure and the ability of the surrounding soil to retard radionuclide migration. The objective of our study was to measure the diffusivity of Re, Tc and I in concrete containment and the surrounding vadose zone soil. Effects of carbonation, presence of metallic iron, and fracturing of concrete and the varying moisture contents in soil on the diffusivities of Tc and I were evaluated.

  10. Therapeutic radionuclides: Making the right choice

    SciTech Connect

    Srivastava, S.C.

    1996-08-01

    Recently, there has been a resurgence of interest in nuclear medicine therapeutic procedures. Using unsealed sources for therapy is not a new concept; it has been around since the beginnings of nuclear medicine. Treatment of thyroid disorders with radioiodine is a classic example. The availability of radionuclides with suitable therapeutic properties for specific applications, as well as methods for their selective targeting to diseased tissue have, however, remained the main obstacles for therapy to assume a more widespread role in nuclear medicine. Nonetheless, a number of new techniques that have recently emerged, (e.g., tumor therapy with radiolabeled monoclonal antibodies, treatment of metastatic bone pain, etc.) appear to have provided a substantial impetus to research on production of new therapeutic radionuclides. Although there are a number of new therapeutic approaches requiring specific radionuclides, only selected broad areas will be used as examples in this article.

  11. Peptide receptor radionuclide therapy of neuroendocrine tumours.

    PubMed

    Brabander, Tessa; Teunissen, Jaap J M; Van Eijck, Casper H J; Franssen, Gaston J H; Feelders, Richard A; de Herder, Wouter W; Kwekkeboom, Dik J

    2016-01-01

    In the past decades, the number of neuroendocrine tumours that are detected is increasing. A relative new and promising therapy for patients with metastasised or inoperable disease is peptide receptor radionuclide therapy (PRRT). This therapy involves an infusion of somatostatin analogues linked to radionuclides like Yttrium-90 or Lutetium-177. Objective response rates are reported in 15-35%. Response rates may vary between type of tumour and radionuclide. Besides the objective response rate, overall survival and progression free survival increase significantly. Also, the quality of life improves as well. Serious side-affects are rare. PRRT is usually well tolerated, also in patients with extensive metastasised disease. Recent studies combined PRRT with other types of therapies. Unfortunately no randomised trials comparing these strategies are available. In the future, more research is needed to evaluate the best therapy combinations or sequence of therapies. PMID:26971847

  12. Reconsidering Current Decorporation Strategies after Incorporation of Radionuclides.

    PubMed

    Rump, A; Stricklin, D; Lamkowski, A; Eder, S; Abend, M; Port, M

    2016-08-01

    In the case of a nuclear accident or a terrorist attack by a "dirty bomb," there is a risk of external and internal contamination with radionuclides in addition to external irradiation. Internal irradiation as a consequence of radionuclide incorporation is associated with a higher risk of stochastic radiation effects (e.g., tumors). Decorporation treatment will enhance the elimination of radionuclides and reduce the committed effective dose as a metric of stochastic health effects. Although treatment efficacy is better when started early, beginning the therapy without knowing the committed effective dose may unnecessarily expose the patient to the side effects of the medication. The question is: Delay the therapy to wait for the results of internal dosimetry or start the therapy promptly on spec? To prove insight into this question, a selective review of the literature was conducted. The importance of the initiation time of treatment in the efficacy of decorporation treatment can be explained with pharmacokinetic laws and first order processes determining the disposition of xenobiotics in the organism. Nevertheless, there is no internationally accepted standard on when to start a decorporation therapy (exception: iodide). The "precautionary approach," emphasizing the importance of the committed effective dose for the indication of treatment, is competing with the "urgent approach" advocating the administration of medication "a priori" within several hours. A review of the literature actually indicates that the most important drugs used for decorporation are well tolerated with few adverse effects. In consideration of the higher efficacy and the low side-effects of a short-term treatment, initiating decorporation therapy as soon as possible after internal contamination, even before the committed effective dose has been assessed, appears to be a reasonable approach. The decision of continuation or discontinuation of the therapy should be taken after internal

  13. Bacterially produced calcium phosphate nanobiominerals: sorption capacity, site preferences, and stability of captured radionuclides.

    PubMed

    Handley-Sidhu, S; Hriljac, J A; Cuthbert, M O; Renshaw, J C; Pattrick, R A D; Charnock, J M; Stolpe, B; Lead, J R; Baker, S; Macaskie, L E

    2014-06-17

    A Serratia sp. bacterium manufactures amorphous calcium phosphate nanominerals (BHAP); this material has shown increased sorption capacity for divalent radionuclide capture. When heat-treated (≥450 °C) the cell biomass is removed and the biominerals are transformed to hydroxyapatite (HAP). Using a multimethod approach, we have elucidated both the site preferences and stability of analogue radionuclide incorporation for Sr, Co, Eu, and U. Strontium incorporates within the bulk amorphous inorganic phase of BHAP; however, once temperature modified to crystalline HAP, bonding was consistent with Sr substitution at the Ca(1) and/or Ca(2) sites. Cobalt incorporation occurs within the bulk inorganic amorphous phase of BHAP and within the amorphous grain boundaries of HAP. Europium (an analogue for trivalent actinides) substituted at the Ca(2) and/or the Ca(3) position of tricalcium phosphate, a known component of HAP grain boundaries. Uranium was surface complexed with no secondary minerals detected. With multiple sites for targeted radionuclide incorporation, high loadings, and good stability against remobilization, BHAP is shown to be a potential material for the remediation of aqueous radionuclide in groundwater. PMID:24823240

  14. Bacterially produced calcium phosphate nanobiominerals: sorption capacity, site preferences, and stability of captured radionuclides.

    PubMed

    Handley-Sidhu, S; Hriljac, J A; Cuthbert, M O; Renshaw, J C; Pattrick, R A D; Charnock, J M; Stolpe, B; Lead, J R; Baker, S; Macaskie, L E

    2014-06-17

    A Serratia sp. bacterium manufactures amorphous calcium phosphate nanominerals (BHAP); this material has shown increased sorption capacity for divalent radionuclide capture. When heat-treated (≥450 °C) the cell biomass is removed and the biominerals are transformed to hydroxyapatite (HAP). Using a multimethod approach, we have elucidated both the site preferences and stability of analogue radionuclide incorporation for Sr, Co, Eu, and U. Strontium incorporates within the bulk amorphous inorganic phase of BHAP; however, once temperature modified to crystalline HAP, bonding was consistent with Sr substitution at the Ca(1) and/or Ca(2) sites. Cobalt incorporation occurs within the bulk inorganic amorphous phase of BHAP and within the amorphous grain boundaries of HAP. Europium (an analogue for trivalent actinides) substituted at the Ca(2) and/or the Ca(3) position of tricalcium phosphate, a known component of HAP grain boundaries. Uranium was surface complexed with no secondary minerals detected. With multiple sites for targeted radionuclide incorporation, high loadings, and good stability against remobilization, BHAP is shown to be a potential material for the remediation of aqueous radionuclide in groundwater.

  15. Microbiological Transformations of Radionuclides in the Subsurface

    SciTech Connect

    Marshall, Matthew J.; Beliaev, Alex S.; Fredrickson, Jim K.

    2010-01-04

    Microorganisms are ubiquitous in subsurface environments although their populations sizes and metabolic activities can vary considerably depending on energy and nutrient inputs. As a result of their metabolic activities and the chemical properties of their cell surfaces and the exopolymers they produce, microorganisms can directly or indirectly facilitate the biotransformation of radionuclides, thus altering their solubility and overall fate and transport in the environment. Although biosorption to cell surfaces and exopolymers can be an important factor modifying the solubility of some radionuclides under specific conditions, oxidation state is often considered the single most important factor controlling their speciation and, therefore, environmental behavior.

  16. External accumulation of radionuclide in hepatic hydrothorax

    SciTech Connect

    Albin, R.J.; Johnston, G.S.

    1989-05-01

    Hepatic hydrothorax is a complication in approximately 5% of patients with cirrhosis. Ascites is almost always present and helps to suggest the correct diagnosis. However, when ascites is absent, radionuclide imaging has proven to be helpful in establishing that the pleural effusion originated from ascitic fluid. When pleural fluid is rapidly removed, such as by thoracostomy tube drainage, the radioisotope may accumulate outside the thorax and produce a negative scan of the chest. When the radionuclide scan is nondiagnostic and the pleural space is being rapidly drained, the pleural fluid collecting system should always be imaged before rejecting a diagnosis of hepatic hydrothorax.

  17. Radionuclide imaging of the urinary tract

    SciTech Connect

    Velchik, M.G.

    1985-11-01

    This article describes the role of nuclear medicine in the evaluation of the genitourinary tract. The technical aspects of radionuclide imaging (radiopharmaceuticals, radiation dosimetry, instrumentation, and method) are briefly presented, and each of the indications for renal scintigraphy--including the evaluation of differential renal function, hypertension, obstruction, renal transplants, masses, trauma, congenital anomalies, vesicoureteral reflux, and infection--are discussed. The relative advantages and disadvantages of radionuclide imaging with respect to alternative radiographic examinations (such as intravenous urography, ultrasonography, CT, angiography, and magnetic resonance imaging) are emphasized wherever applicable. 136 references.

  18. Radionuclide scanning in children with rhabdomyosarcoma

    SciTech Connect

    Weinblatt, M.E.; Miller, J.H.

    1981-01-01

    Radionuclide scintigraphy was performed in 46 children with rhabdomyosarcoma. Of the 63 radiologically confirmed sites of bone disease, 76% were detected by /sup 99m/Tc-labeled phosphate uptake. All 15 sites of hepatic involvement and eight of the nine cranial sites of disease exhibited isotope accumulation. Gallium 67 scans showed 57% of the 43 proven sites of disease, including four previously unsuspected areas. Twelve false-positive sites were obtained with gallium. Radionuclide scanning is a valuable aid in the diagnostic evaluation and management of childhood rhabdomyosarcoma.

  19. Sequim Site Radionuclide Air Emissions Report for Calendar Year 2012

    SciTech Connect

    Snyder, Sandra F.; Barnett, J. Matthew; Gervais, Todd L.

    2013-04-01

    This report is prepared to document compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities and ashington Administrative Code (WAC) Chapter 246-247, Radiation Protection Air Emissions. This report meets the calendar year 2012 Sequim Site annual reporting requirement for its operations as a privately-owned facility as well as its federally-contracted status that began in October 2012. Compliance is indicated by comparing the estimated dose to the maximally exposed individual (MEI) with the 10 mrem/yr Environmental Protection Agency (EPA) standard. The MSL contains only sources classified as fugitive emissions. Despite the fact that the regulations are intended for application to point source emissions, fugitive emissions are included with regard to complying with the EPA standard. The dose to the Sequim Site MEI due to routine operations in 2012 was 9E-06 mrem (9E-08 mSv). No non-routine emissions occurred in 2012. The MSL is in compliance with the federal and state 10 mrem/yr standard.

  20. Assessment of Radionuclides in the Savannah River Site Environment Summary

    SciTech Connect

    Carlton, W.H.

    1999-01-26

    This document summarizes the impact of radionuclide releases from Savannah River Site (SRS) facilities from 1954 through 1996. The radionuclides reported here are those whose release resulted in the highest dose to people living near SRS.

  1. Secondary waste form testing : ceramicrete phosphate bonded ceramics.

    SciTech Connect

    Singh, D.; Ganga, R.; Gaviria, J.; Yusufoglu, Y.

    2011-06-21

    The cleanup activities of the Hanford tank wastes require stabilization and solidification of the secondary waste streams generated from the processing of the tank wastes. The treatment of these tank wastes to produce glass waste forms will generate secondary wastes, including routine solid wastes and liquid process effluents. Liquid wastes may include process condensates and scrubber/off-gas treatment liquids from the thermal waste treatment. The current baseline for solidification of the secondary wastes is a cement-based waste form. However, alternative secondary waste forms are being considered. In this regard, Ceramicrete technology, developed at Argonne National Laboratory, is being explored as an option to solidify and stabilize the secondary wastes. The Ceramicrete process has been demonstrated on four secondary waste formulations: baseline, cluster 1, cluster 2, and mixed waste streams. Based on the recipes provided by Pacific Northwest National Laboratory, the four waste simulants were prepared in-house. Waste forms were fabricated with three filler materials: Class C fly ash, CaSiO{sub 3}, and Class C fly ash + slag. Optimum waste loadings were as high as 20 wt.% for the fly ash and CaSiO{sub 3}, and 15 wt.% for fly ash + slag filler. Waste forms for physical characterizations were fabricated with no additives, hazardous contaminants, and radionuclide surrogates. Physical property characterizations (density, compressive strength, and 90-day water immersion test) showed that the waste forms were stable and durable. Compressive strengths were >2,500 psi, and the strengths remained high after the 90-day water immersion test. Fly ash and CaSiO{sub 3} filler waste forms appeared to be superior to the waste forms with fly ash + slag as a filler. Waste form weight loss was {approx}5-14 wt.% over the 90-day immersion test. The majority of the weight loss occurred during the initial phase of the immersion test, indicative of washing off of residual unreacted

  2. The Current Limits for Radionuclides in Food in Japan.

    PubMed

    Iwaoka, Kazuki

    2016-11-01

    After the TEPCO Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident, the current limits in Japan on the radionuclide contamination of food [100 Bq kg for general foods, 50 Bq kg for milk and infant foods, and 10 Bq kg for drinking water as radioactive cesium (Cs + Cs)] were established on the basis of an effective dose of 1 mSv y, consistent with international standards to mitigate the exposure of the general public to radiation. Measures that include recalling or restriction of food have been taken in cases when these limits were violated. As a result of these efforts, the actual effective doses of radioactive cesium (Cs + Cs) in foods approximately 1 y after the FDNPP accident were below 0.01 mSv y. However, there is little information on the current status of these limits in the literature, which necessitates a comprehensive review of the information that exists. In this paper, the concept behind the introduction of these limits, the methods by which they were derived, and the results of monitoring food accordingly, are reviewed. This information will be helpful in the case of a future accident, and it will also help to enhance the understanding of the current limits and to relieve the anxieties of the general public concerning radiation exposure from radionuclides in food.

  3. Theranostic Applications of Lutetium-177 in Radionuclide Therapy.

    PubMed

    Das, Tapas; Banerjee, Sharmila

    2016-01-01

    Lutetium-177 has been widely discussed as a radioisotope of choice for targeted radionuclide therapy. The simultaneous emission of imageable gamma photons [208 keV (11%) and 113 keV (6.4%)] along with particulate β(-) emission [β(max) = 497 keV] makes it a theranostically desirable radioisotope. In the present article, the possibility of using two 177Lu-based agents viz. 177Lu-EDTMP and 177Lu-DOTATATE for theranostic applications in metastatic bone pain palliation (MBPP) and peptide receptor radionuclide therapy (PRRT), have been explored. In the case of 177Lu-EDTMP, the whole-body images obtained are compared with those recorded using 99mTc-MDP in the same patient. On the other hand, pre-therapy images acquired with 177Lu-DOTA-TATE are compared with similar images obtained with standard agents, such as 99mTc-HYNIC-TOC (SPECT) and 68Ga-DOTA-TOC (PET) in the same patient. The advantage of the long physical half-life (T1/2) of 177Lu has been utilized in mapping the pharmacokinetics of two additional agents, 177Lu-labeled hydroxyapatite (HA) in radiation synovectomy of knee joints and 177Lu-HA for therapy of hepatocellular carcinoma. Results of these multiple studies conclusively document the potential of 177Lu as a theranostic radioisotope.

  4. The Current Limits for Radionuclides in Food in Japan.

    PubMed

    Iwaoka, Kazuki

    2016-11-01

    After the TEPCO Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident, the current limits in Japan on the radionuclide contamination of food [100 Bq kg for general foods, 50 Bq kg for milk and infant foods, and 10 Bq kg for drinking water as radioactive cesium (Cs + Cs)] were established on the basis of an effective dose of 1 mSv y, consistent with international standards to mitigate the exposure of the general public to radiation. Measures that include recalling or restriction of food have been taken in cases when these limits were violated. As a result of these efforts, the actual effective doses of radioactive cesium (Cs + Cs) in foods approximately 1 y after the FDNPP accident were below 0.01 mSv y. However, there is little information on the current status of these limits in the literature, which necessitates a comprehensive review of the information that exists. In this paper, the concept behind the introduction of these limits, the methods by which they were derived, and the results of monitoring food accordingly, are reviewed. This information will be helpful in the case of a future accident, and it will also help to enhance the understanding of the current limits and to relieve the anxieties of the general public concerning radiation exposure from radionuclides in food. PMID:27682906

  5. Migration of radionuclides in geologic media: Fundamental research needs

    SciTech Connect

    Reed, D.T. ); Zachara, J.M.; Wildung, R.E. ); Wobber, F.J. )

    1990-01-01

    An assessment of the fundamental research needs in understanding and predicting the migration of radionuclides in the subsurface is provided. Emphasis is on the following three technical areas: (1) aqueous speciation of radionuclides, (2) the interaction of radionuclides with substrates, and (3) intermediate-scale interaction studies. This research relates to important issues associated with environmental restoration and remediation of DOE sites contaminated with mixed radionuclide-organic wastes. 64 refs., 1 fig., 1 tab.

  6. REMOVAL OF RADIONUCLIDES BY ELECTROKINETIC SOIL PROCESSING

    EPA Science Inventory

    Electrokinetics promises to be an innovative treatment process for in-situ treatment of soils and groundwater contaminated with heavy metals and radionuclides. Electrokinetics refers to the movement of ionic liquids and charged particles relative to one another under the action ...

  7. Understanding Radionuclide Interactions with Layered Materials

    NASA Astrophysics Data System (ADS)

    Wang, Y.

    2015-12-01

    Layered materials play an important role in nuclear waste management and environmental cleanup. Better understanding of radionuclide interactions with those materials is critical for engineering high-performance materials for various applications. This presentation will provide an overview on radionuclide interactions with two general categories of layered materials - cationic clays and anionic clays - from a perspective of nanopore confinement. Nanopores are widely present in layered materials, either as the interlayers or as inter-particle space. Nanopore confinement can significantly modify chemical reactions in those materials. This effect may cause the preferential enrichment of radionuclides in nanopores and therefore directly impact the mobility of the radionuclides. This effect also implies that conventional sorption measurements using disaggregated samples may not represent chemical conditions in actual systems. The control of material structures on ion exchange, surface complexation, and diffusion in layered materials will be systematically examined, and the related modeling approaches will be discussed. This work was performed at Sandia National Laboratories, which is a multiprogram laboratory operated by Sandia Corporation, a Lockheed-Martin Company, for the DOE under contract DE-AC04-94AL8500.

  8. Distribution of radionuclides in Dardanelle Reservoir sediments.

    PubMed

    Forgy, J R; Epperson, C E; Swindle, D L

    1984-02-01

    Natural and reactor-discharged gamma-ray emitting radionuclides were measured in Dardanelle Reservoir surface sediments taken near the Arkansas Nuclear One Power Plant site. Samples represented several water depths and particle sizes, at 33 locations, in a field survey conducted in early September 1980. Radionuclide contents of dry sediments ranged as follows: natural radioactivity (40K as well as uranium and thorium decay products) 661-1210 Bq/kg; and reactor discharged radioactivity (137Cs, 134Cs, 60Co,, 58Co, 54Mn), no detectable activity to 237 Bq/kg. In general, radionuclide contents were positively correlated with decreasing sediment particle size. The average external whole-body and skin doses from all measurable reactor-discharged radionuclides were calculated according to the mathematical formula for determining external dose from sediment given by the U.S. Nuclear Regulatory Commission (NRC). Inside the discharge embayment near the reactor discharge canal, the doses were 1.7 X 10(-3) mSv/yr to the whole body and 2.0 X 10(-3) mSv/yr to the skin. Outside this area, the doses were 0.15 X 10(-3) and 0.18 X 10(-3) mSv/yr to the whole body and skin, respectively. PMID:6693264

  9. Physical and chemical properties of radionuclide therapy.

    PubMed

    Wessels, B W; Meares, C F

    2000-04-01

    As more radionuclide therapies move from laboratory feasibility studies into clinical reality, it becomes increasingly important for the labeling chemistry to produce consistently a stable radiopharmaceutical that remains intact under the challenge of human catabolism. Similarly, once proof of principle is established to bring a radionuclide conjugate into clinical therapy trials, dosimetric estimates should be made to select the appropriate radionuclide properties, which are based on animal-specific or patient-specific pharmacokinetics and match a set of specific clinical endpoints. These properties may include the radionuclide physical half-life, radiolabeled conjugate biological uptake and clearance, product-specific activity, range and type of emissions, and resultant effects on tumor and normal tissue cellular survival. The immunologist and labeling chemist have now produced a variety of strategies that have potential to increase the therapeutic ratio (tumor-to-normal tissue dose ratio). The advent of normal tissue clearing agents, fragmented or chimerized carriers to improve targeting, and the method of bispecific or two-step and three-step targeting agents has increased the need for realistic modeling of the carrier in vivo to guide prospectively the competitive development of these radiopharmaceuticals. In this article, examples have been taken from the literature to elucidate the benchmark of success that careful experimental design has fostered to bring these agents into clinical practice by creative and logical methodologies.

  10. RADIONUCLIDE TRANSPORT MODELS UNDER AMBIENT CONDITIONS

    SciTech Connect

    S. Magnuson

    2004-11-01

    The purpose of this model report is to document the unsaturated zone (UZ) radionuclide transport model, which evaluates, by means of three-dimensional numerical models, the transport of radioactive solutes and colloids in the UZ, under ambient conditions, from the repository horizon to the water table at Yucca Mountain, Nevada.

  11. Radionuclides of radium in water

    SciTech Connect

    Not Available

    1981-01-01

    The method covers the separation of dissolved radium from water for the purpose of measuring its radioactivity. While all radium isotopes are included, the method is limited to alpha-emitting radioisotopes by choice of radiation detector. The most important of these isotopes are radium-223, radium-224, and radium-226. The lower limit of concentration to which this method is applicable is 1 pCi/liter; it may be applied to higher concentration by reduction of sample size. The method includes a discussion of interference, apparatus, reagents, sampling, calibration and standardization, procedure, calculation, and precision. (JMT)

  12. 21 CFR 892.1390 - Radionuclide rebreathing system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Radionuclide rebreathing system. 892.1390 Section 892.1390 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1390 Radionuclide rebreathing system. (a) Identification. A radionuclide...

  13. 21 CFR 892.5750 - Radionuclide radiation therapy system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Radionuclide radiation therapy system. 892.5750... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5750 Radionuclide radiation therapy system. (a) Identification. A radionuclide radiation therapy system is a device intended to permit...

  14. 21 CFR 892.5750 - Radionuclide radiation therapy system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Radionuclide radiation therapy system. 892.5750... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5750 Radionuclide radiation therapy system. (a) Identification. A radionuclide radiation therapy system is a device intended to permit...

  15. 21 CFR 892.5730 - Radionuclide brachytherapy source.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Radionuclide brachytherapy source. 892.5730... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5730 Radionuclide brachytherapy source. (a) Identification. A radionuclide brachytherapy source is a device that consists of...

  16. 21 CFR 892.5730 - Radionuclide brachytherapy source.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Radionuclide brachytherapy source. 892.5730... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5730 Radionuclide brachytherapy source. (a) Identification. A radionuclide brachytherapy source is a device that consists of...

  17. 21 CFR 892.5730 - Radionuclide brachytherapy source.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Radionuclide brachytherapy source. 892.5730... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5730 Radionuclide brachytherapy source. (a) Identification. A radionuclide brachytherapy source is a device that consists of...

  18. Intercomparison of radionuclide calibrator measurements in U.K. hospitals.

    PubMed

    Woods, M J

    1983-01-01

    The Life Sciences Working Group of the International Committee for Radionuclide Metrology had received various reports of users of radionuclide calibrators experiencing problems in obtaining accurate measurements of radionuclide activity. Working Group members were encouraged to initiate surveys in their own countries to assess the magnitude of these problems. The results of the survey in the United Kingdom are given.

  19. 21 CFR 892.5700 - Remote controlled radionuclide applicator system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Remote controlled radionuclide applicator system. 892.5700 Section 892.5700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... radionuclide applicator system. (a) Identification. A remote controlled radionuclide applicator system is...

  20. 21 CFR 892.5700 - Remote controlled radionuclide applicator system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Remote controlled radionuclide applicator system. 892.5700 Section 892.5700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... radionuclide applicator system. (a) Identification. A remote controlled radionuclide applicator system is...

  1. 21 CFR 892.5700 - Remote controlled radionuclide applicator system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Remote controlled radionuclide applicator system. 892.5700 Section 892.5700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... radionuclide applicator system. (a) Identification. A remote controlled radionuclide applicator system is...

  2. 21 CFR 892.5700 - Remote controlled radionuclide applicator system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Remote controlled radionuclide applicator system. 892.5700 Section 892.5700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... radionuclide applicator system. (a) Identification. A remote controlled radionuclide applicator system is...

  3. Drinking-water standards

    SciTech Connect

    Munro, N.B.; Travis, C.C.

    1986-08-01

    This paper discussed the revising of the primary and secondary drinking-water regulations by EPA in accordance with the Safe Drinking Water Act. Since consideration of risk is playing an increasing role in setting environmental standards, questions were raised regarding the adequacy of human health protection afforded by some of the existing and proposed standards. 1 table.

  4. Scientific Analysis Cover Sheet for Radionuclide Screening

    SciTech Connect

    G. Ragan

    2002-08-09

    The waste forms under consideration for disposal in the proposed repository at Yucca Mountain contain scores of radionuclides (Attachments V and VI). It would be impractical and highly inefficient to model all of these radionuclides in a total system performance assessment (TSPA). Thus, the purpose of this radionuclide screening analysis is to remove from further consideration (screen out) radionuclides that are unlikely to significantly contribute to radiation dose to the public from the proposed nuclear waste repository at Yucca Mountain. The remaining nuclides (those screened in) are recommended for consideration in TSPA modeling for license application. This analysis also covers radionuclides that are not screened in based on dose, but need to be included in TSPA modeling for other reasons. For example, U.S. Environmental Protection Agency (EPA) and U.S. Nuclear Regulatory Commission (NRC) regulations require consideration of the combined activity of Ra-226 and Ra-228 in groundwater (40 CFR 197.30, 10 CFR 63.331). Also, Cm-245, Pu-241, and U-235 decay indirectly to potentially important radionuclides, and are not identified by the screening analysis as important. The radionuclide screening analysis separately considers two different postclosure time periods: the 10,000-y regulatory period for the proposed repository at Yucca Mountain and the period after 10,000 y up to 1 million y after emplacement. The incremental effect of extending the screening for the regulatory period to 20,000 y is also addressed. Four release scenarios are considered: (1) the nominal scenario, which entails long-term degradation of disposal containers and waste forms, (2) a human-intrusion scenario, (3) an intrusive igneous event, and (4) an eruptive igneous event. Because the first three scenarios require groundwater transport, they are called groundwater scenarios below. The screening analysis considers the following waste forms: spent boiling water reactor (BWR) fuel, spent

  5. Sediment and radionuclide transport in rivers: radionuclide transport modeling for Cattaraugus and Buttermilk Creeks, New York

    SciTech Connect

    Onishi, Y.; Yabusaki, S.B.; Kincaid, C.T.; Skaggs, R.L.; Walters, W.H.

    1982-12-01

    SERATRA, a transient, two-dimensional (laterally-averaged) computer model of sediment-contaminant transport in rivers, satisfactorily resolved the distribution of sediment and radionuclide concentrations in the Cattaraugus Creek stream system in New York. By modeling the physical processes of advection, diffusion, erosion, deposition, and bed armoring, SERATRA routed three sediment size fractions, including cohesive soils, to simulate three dynamic flow events. In conjunction with the sediment transport, SERATRA computed radionuclide levels in dissolved, suspended sediment, and bed sediment forms for four radionuclides (/sup 137/Cs, /sup 90/Sr, /sup 239/ /sup 240/Pu, and /sup 3/H). By accounting for time-dependent sediment-radionuclide interaction in the water column and bed, SERATA is a physically explicit model of radionuclide fate and migration. Sediment and radionuclide concentrations calculated by SERATA in the Cattaraugus Creek stream system are in reasonable agreement with measured values. SERATRA is in the field performance phase of an extensive testing program designed to establish the utility of the model as a site assessment tool. The model handles not only radionuclides but other contaminants such as pesticides, heavy metals and other toxic chemicals. Now that the model has been applied to four field sites, including the latest study of the Cattaraugus Creek stream system, it is recommended that a final model be validated through comparison of predicted results with field data from a carefully controlled tracer test at a field site. It is also recommended that a detailed laboratory flume be tested to study cohesive sediment transport, deposition, and erosion characteristics. The lack of current understanding of these characteristics is one of the weakest areas hindering the accurate assessment of the migration of radionuclides sorbed by fine sediments of silt and clay.

  6. Targeted radionuclide therapy--an overview.

    PubMed

    Dash, Ashutosh; Knapp, F F Russ; Pillai, M R A

    2013-09-01

    Radionuclide therapy (RNT) based on the concept of delivering cytotoxic levels of radiation to disease sites is one of the rapidly growing fields of nuclear medicine. Unlike conventional external beam therapy, RNT targets diseases at the cellular level rather than on a gross anatomical level. This concept is a blend of a tracer moiety that mediates a site specific accumulation followed by induction of cytotoxicity with the short-range biological effectiveness of particulate radiations. Knowledge of the biochemical reactions taking place at cellular levels has stimulated the development of sophisticated molecular carriers, catalyzing a shift towards using more specific targeting radiolabelled agents. There is also improved understanding of factors of importance for choice of appropriate radionuclides based on availability, the types of emissions, linear energy transfer (LET), and physical half-life. This article discusses the applications of radionuclide therapy for treatment of cancer as well as other diseases. The primary objective of this review is to provide an overview on the role of radionuclide therapy in the treatment of different diseases such as polycythaemia, thyroid malignancies, metastatic bone pain, radiation synovectomy, hepatocellular carcinoma (HCC), neuroendocrine tumors (NETs), non-Hodgkin's lymphoma (NHL) and others. In addition, recent developments on the systematic approach in designing treatment regimens as well as recent progress, challenges and future perspectives are discussed. An examination of the progress of radionuclide therapy indicates that although a rapid stride has been made for treating hematological tumors, the development for treating solid tumors has, so far, been limited. However, the emergence of novel tumor-specific targeting agents coupled with successful characterization of new target structures would be expected to pave the way for future treatment for such tumors.

  7. Labeling of monoclonal antibodies with radionuclides

    SciTech Connect

    Bhargava, K.K.; Acharya, S.A. )

    1989-07-01

    Antibodies, specifically monoclonal antibodies, are potentially very useful and powerful carriers of therapeutic agents to target tissues and diagnostic agents. The loading or charging of antibodies with agents, especially radiotracers, is reviewed here. The choice of radioisotope for immunodetection and/or immunotherapy is based on its availability, half-life, nature of the radiation emitted, and the metabolic pathways of the radionuclide in the body. Most important of all are the derivatization techniques available for labeling the antibody with the given radionuclide. Isotopes of iodine and divalent metal ions are the most commonly used radionuclides. Antibodies labeled with iodine at tyrosine residues are metabolized rapidly in vivo. This leads to the incorporation of metabolized radioactive iodine into various tissues, mainly the thyroid gland and stomach, and to the accumulation of high levels of circulating iodine in the blood, which masks tumor uptake considerably. To overcome these limitations, the use of iodohippurate as an iodine-anchoring molecule to the protein should be considered. When divalent or multivalent metal ions are used as the preferred radionuclide, bifunctional chelating reagents such as EDTA or DTPA are first coupled to the protein or antibody. These chelating molecules are attached to the protein by formation of an isopeptide linkage between the carboxylate of the chelating reagent and the amino group of the protein. Several procedures are available to generate the isopeptide linkage. When the anchoring of the chelating agent through isopeptide linkage results in the inactivation of the antibody, periodate oxidation of the carbohydrate moiety of the antibody, followed by reductive coupling of chelator, could be considered as an alternative. There is still a need for better, simpler, and more direct methods for labeling antibodies with radionuclides. 78 references.

  8. Anthropogenic radionuclides in the atmosphere observed at Tsukuba: characteristics of the radionuclides derived from Fukushima.

    PubMed

    Doi, Taeko; Masumoto, Kazuyoshi; Toyoda, Akihiro; Tanaka, Atsushi; Shibata, Yasuyuki; Hirose, Katsumi

    2013-08-01

    During a serious accident at the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), a huge quantity of radionuclides was released into the atmosphere and ocean. We measured anthropogenic radionuclides in surface air at Tsukuba, about 170 km from the FDNPP. On March 15, 2011, we detected the radioactivity released from the Fukushima accident in air samples at Tsukuba. The major radionuclides that we observed were radioiodine ((131)I, (132)I, (133)I) and radiocesium ((134)Cs, (136)Cs, (137)Cs). This radioiodine consisted of gaseous and particulate forms; the percentage of particulate (131)I in the total (131)I ranged from 0 to 86%. The percentage of the particulate (131)I to the total (131)I increased on the arrival of the plumes from major emissions of the FDNPP. After activities of the radionuclides attained the maximum on March 15, 2011, the FDNPP-derived radionuclides decreased rapidly in surface air. The activity median aerodynamic diameter of (131)I-bearing particles was 0.7 μm, while those of (134)Cs- and (137)Cs-bearing particles were larger than 1 μm. Large variations of ratios of (131)I/(137)Cs, (132)Te/(137)Cs, and (99)Mo ((99m)Tc)/(137)Cs (all involving different elements) suggest that the behaviors of these radionuclides in the atmosphere, including the processes of their emission, differed each other.

  9. Minimum Competency in Secondary Education.

    ERIC Educational Resources Information Center

    De Landsheere, Viviane

    1987-01-01

    Discusses issues related to the movement toward minimum competency in secondary education. Addresses the problem of defining minimum competency and the dangers of imposed standardization. Identifies three conceptualizations of minimum competency as: (1) the narrowly educational standpoint, (2) the concern with functional literacy, and (3) a more…

  10. Radionuclide measurements by accelerator mass spectrometry at Arizona

    NASA Technical Reports Server (NTRS)

    Jull, A. J. T.; Donahue, D. J.; Zabel, T. H.

    1986-01-01

    Over the past years, Tandem Accelerator Mass Spectrometry (TAMS) has become established as an important method for radionuclide analysis. In the Arizona system the accelerator is operated at a thermal voltage of 1.8MV for C-14 analysis, and 1.6 to 2MV for Be-10. Samples are inserted into a cesium sputter ion source in solid form. Negative ions sputtered from the target are accelerated to about 25kV, and the injection magnet selects ions of a particular mass. Ions of the 3+ charge state, having an energy of about 9MeV are selected by an electrostatic deflector, surviving ions pass through two magnets, where only ions of the desired mass-energy product are selected. The final detector is a combination ionization chamber to measure energy loss (and hence, Z), and a silicon surface-barrier detector which measures residual energy. After counting the trace iosotope for a fixed time, the injected ions are switched to the major isotope used for normalization. These ions are deflected into a Faraday cup after the first high-energy magnet. Repeated measurements of the isotope ratio of both sample and standards results in a measurement of the concentration of the radionuclide. Recent improvements in sample preparation for C-14 make preparation of high-beam current graphite targets directly from CO2 feasible. Except for some measurements of standards and backgrounds for Be-10 measurements to date have been on C-14. Although most results have been in archaeology and quaternary geology, studies have been expanded to include cosmogenic C-14 in meteorites. The data obtained so far tend to confirm the antiquity of Antarctic meteorites from the Allan Hills site. Data on three samples of Yamato meteorites gave terrestrial ages of between about 3 and 22 thousand years.

  11. Uptake by plants of radionuclides from FUSRAP waste materials

    SciTech Connect

    Knight, M.J.

    1983-04-01

    Radionuclides from FUSRAP wastes potentially may be taken up by plants during remedial action activities and permanent near-surface burial of contaminated materials. In order to better understand the propensity of radionuclides to accumulate in plant tissue, soil and plant factors influencing the uptake and accumulation of radionuclides by plants are reviewed. In addition, data describing the uptake of the principal radionuclides present in FUSRAP wastes (uranium-238, thorium-230, radium-226, lead-210, and polonium-210) are summarized. All five radionuclides can accumulate in plant root tissue to some extent, and there is potential for the translocation and accumulation of these radionuclides in plant shoot tissue. Of these five radionuclides, radium-226 appears to have the greatest potential for translocation and accumulation in plant shoot tissue. 28 references, 1 figure, 3 tables.

  12. Cancer mortality in relation to monitoring for radionuclide exposure in three UK nuclear industry workforces.

    PubMed Central

    Carpenter, L. M.; Higgins, C. D.; Douglas, A. J.; Maconochie, N. E.; Omar, R. Z.; Fraser, P.; Beral, V.; Smith, P. G.

    1998-01-01

    Cancer mortality in 40,761 employees of three UK nuclear industry facilities who had been monitored for external radiation exposure was examined according to whether they had also been monitored for possible internal exposure to tritium, plutonium or other radionuclides (uranium, polonium, actinium or other unspecified). Death rates from cancer were compared both with national rates and with rates in radiation workers not monitored for exposure to any radionuclides. Among workers monitored for tritium exposure, overall cancer mortality was significantly below national rates [standardized mortality ratio (SMR) = 83, 165 deaths; 2P = 0.02] and none of the cancer-specific death rates was significantly above either the national average or rates in non-monitored workers. Although the overall death rate from cancer in workers monitored for plutonium exposure was also significantly low relative to national rates (SMR = 89, 581 deaths; 2P = 0.005), mortality from pleural cancer was significantly raised (SMR = 357, nine deaths; 2P = 0.002); none of the rates differed significantly from those of non-monitored workers. Workers monitored for radionuclides other than tritium or plutonium also had a death rate from all cancers combined that was below the national average (SMR = 86, 418 deaths; 2P = 0.002) but prostatic cancer mortality was raised both in relation to death rates in the general population (SMR = 153, 37 deaths; 2P = 0.02) and to death rates in radiation workers who had not been monitored for exposure to any radionuclide [rate ratio (RR) = 1.65; 2P = 0.03]. Mortality from cancer of the lung was also significantly increased in workers monitored for other radionuclides compared with those of radiation workers not monitored for exposure to radionuclides (RR = 1.31, 164 deaths; 2P = 0.01). For cancers of the lung, prostate and all cancers combined, death rates in monitored workers were examined according to the timing and duration of monitoring for radionuclide

  13. Radionuclide air emissions report for the Hanford site calendar year 1995

    SciTech Connect

    Gleckler, B.P., Westinghouse Hanford

    1996-06-26

    This report documents radionuclide air emissions from the Hanford Site in 1995, and the resulting effective dose equivalent (FDE) to the maximally exposed member of the public, referred to as the `MEI.` The report has been prepared and will be submitted in accordance with reporting requirements in the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, `National Emissions Standards for Hazardous Air Pollutants,` Subpart H, `National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities.` This report has also been prepared for and will be submitted in accordance with the reporting requirements of the Washington Administrative Code Chapter 246-247, `Radiation Protection-Air Emissions.`

  14. Radionuclide synovectomy – essentials for rheumatologists

    PubMed Central

    Felis-Giemza, Anna; Kobylecka, Małgorzata

    2016-01-01

    Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common arthropathies can also benefit from this method. Radiosynovectomy is safe, well tolerated and efficacious. About 70–80% of patients respond well to the therapy. However, the therapeutic effects are considerably worse in patients with co-existent osteoarthritis and advanced joint degeneration. Despite its advantages, radionuclide synovectomy is not performed as often as it could be, so greater knowledge and understanding of this method are needed. The authors present the most important facts about radiosynovectomy that may help rheumatologists in their daily clinical practice. PMID:27504020

  15. Decline of radionuclides in Columbia River biota

    SciTech Connect

    Cushing, C.E.; Watson, D.G.; Scott, A.J.; Gurtisen, J.M.

    1980-03-01

    In January 1971, the last of nine plutonium production reactors using direct discharge of once-through cooling waters into the Columbia River was closed. Sampling was initiated at three stations on the Columbia River to document the decline of the radionuclide body burdens in the biota of the Columbia River ecosystem. The data show that in a river-reservoir complex, the measurable body burden of fission-produced radionuclides decreased to essentially undetectable levels within 18 to 24 mo after cessation of discharge of once-through cooling water into the river. On the basis of data from the free-flowing station, we believe that this decrease would be even more rapid in an unimpounded river.

  16. Improving cancer treatment with cyclotron produced radionuclides

    SciTech Connect

    Larson, S.M. Finn, R.D.

    1992-08-04

    This report describes the author's continuing long term goal of promoting nuclear medicine applications by improving the scientific basis for tumor diagnosis treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology. The program has 3 interactive components: Radiochemistry /Cyclotron; Pharmacology; and Immunology. An essential strategy is as follows: novel radionuclides and radiotracers developed in the Radiochemistry/Cyclotron section under the DOE grant during the 1989--1992 grant period, will be employed in the Pharmacology and Immunology sections of the DOE grant during the 1992--1995 grant period. The development of novel radionuclides and tracers is of course useful in and of itself, but their utility is greatly enhanced by the interaction with the immunology and pharmacology components of the program.

  17. [Radionuclide therapy for bone metastases: new opportunities].

    PubMed

    Krylov, V V; Kochetova, T Yu; Voloznev, L V

    2015-01-01

    Treatment of patients with multiple bone metastases accompanied by pain syndrome is a complicated clinical task. Radionuclide therapy is one of its solutions, which is used to achieve long reduction of pain syndrome and significant improvement the quality of patients' life. However mechanism of action of bone-seeking radiopharmaceuticals suggests not only pain control but antitumor effect as well. In early clinical studies of safety and efficacy of the most common bone-seeking radiopharmaceuticals in single administration there were not any preferences in overall survival but individual clinical cases with extraordinary tumor regression after radionuclide therapy were reported. Repeated bone targeted therapy and combination with other treatment modalities can help to gain statistical significant increase in overall survival of patients.

  18. Radionuclide demonstration of intrapulmonary shunting in cirrhosis

    SciTech Connect

    Bank, E.R.; Thrall, J.H.; Dantzker, D.R.

    1983-05-01

    The association of hepatic cirrhosis and severe arterial hypoxemia has been well described. Although alterations in ventilatory function may partially account for the hypoxemia, the principal mechanism is thought to be a microangiopathic change in the pulmonary vasculature resulting in intrapulmonary arteriovenous shunting with resultant systemic desaturation. Whole-body radionuclide scans with technetium-99m macroaggregated albumin labeling have been diagnostic of right-to-left shunting by their demonstration of tracer accumulation within the extrapulmonary circulation. A case of severe pulmonary arteriovenous shunting in an alcoholic patient in whom hepatic disease had not been of apparent clinical significance before radionuclide scanning is reported. He did not have cuntaeous angiomata as have all other patients with alcoholic cirrhosis and hypoxemia.

  19. Radionuclide demonstration of intrapulmonary shunting in cirrhosis

    SciTech Connect

    Bank, E.R.; Thrall, J.H.; Dantzker, D.R.

    1983-05-01

    The association of hepatic cirrhosis and severe arterial hypoxemia has been well described. Although alterations in ventilatory function may partially account for the hypoxemia, the principal mechanism is thought to be a microangiopathic change in the pulmonary arteriovenous shunting with resultant systemic desaturation. Whole-body radionuclide scans with technetium-99m macroaggrregated albumin (/sup 99m/Tc MAA) labeling have been diagnostic of right-to-left shunting by their demonstration of tracer accumulation within the extrapulmonary circulation. A case of severe pulmonary arteriovenous shunting in an alcoholic patient in whom hepatic disease had not been of apparent clinical significance before radionuclide scanning is reported. He did not have cutaneous angiomata as have all other patients with alcoholic cirrhosis and hypoxemia.

  20. Radionuclide Air Emissions Report for the Hanford Site Calendar year 1998

    SciTech Connect

    DIEDIKER, L.P.

    1999-06-15

    This report documents radionuclide air emissions from the Hanford Site in I998 and the resulting effective dose equivalent to the maximally exposed individual (MEI) member of the public. The report has been prepared in accordance with the Code of Federal Regulations, Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (40 CFR SI), Subpart H, ''National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities,'' and with the Washington Administrative Code Chapter 246-247, Radiation Protection--Air Emissions. The federal regulations in 40 CFR 61, Subpart H; require the measurement and reporting of radionuclides emitted from Department of Energy facilities and the resulting offsite dose from those emissions. A standard of 10 mrem/yr effective dose equivalent (EDE) is imposed on them. The EDE to the MEI due to routine emissions in 1998 from Hanford Site point sources was 1.3 E-02 mrem (1.3 E-04 mSv), which is 0.13 percent of the federal standard. Chapter 246-247 of the Washington Administrative Code (WAC) requires the reporting of radionuclide emissions from all Department of Energy Hanford Site sources. The state has adopted into these regulations the 40 CFR 61 standard of 10 mrem/yr EDE. The EDE to the MEI attributable to diffuse and fugitive radionuclide air emissions from the Hanford Site in 1998 was 2.5 E-02 mrem (2.5 E-04 mSv). This dose added to the dose from point sources gives a total for all sources of 3.8 E-02 mrem/yr (3.8 E-04 mSv) EDE, which is 0.38 percent of the 10 mrem/yr standard. An unplanned release on August 26, 1998, in the 300 Area of the Hanford Site resulted in a potential dose of 4.1 E-02 mrem to a hypothetical individual at the nearest point of public access to that area. This hypothetical individual was not the MEI since the wind direction on the day of the release was away from the MEI residence. The potential dose from the unplanned event

  1. Skin decontamination of commonly used medical radionuclides.

    PubMed

    Moore, P H; Mettler, F A

    1980-05-01

    The increasing use of radionuclides in medical diagnosis raises the possibility of accidental spills and skin contamination. This study was performed to evaluate the effectiveness of several decontaminating agents. Most nuclides were easily removed to levels of less than 5% of their original activity. Sodium pertechnetate (Tc-99m) was the most difficult compound to remove. Little difference was found between the effectiveness of tap water, soap and water, and two commercially available decontaminating agents.

  2. Radionuclide transfer from feed to camel milk.

    PubMed

    Al-Masri, M S; Al-Hamwi, A; Amin, Y; Safieh, M B; Zarkawi, M; Soukouti, A; Dayyoub, R; Voigt, G; Fesenko, S

    2014-06-01

    The transfer of (137)Cs, (85)Sr, (131)I, (210)Po, (210)Pb and (238)U from feed to camel's milk was investigated in a pilot experiment with three lactating camels. For a period of 60 days, the animals were fed on spiked feed containing the studied radionuclides. They were subsequently returned to a contamination-free diet and monitored for another 90 days. The activity concentrations of (137)Cs, (85)Sr and (131)I in milk decreased with time and reached background levels after 20 days. Equilibrium transfer coefficients and biological half-lives were estimated and transfer coefficients were calculated as (8.1 ± 3.6) × 10(-4), (4.4 ± 1.6) × 10(-2), (7.8 ± 3.9) × 10(-4), (2.7 ± 3.5) × 10(-4), (1.8 ± 1.5) × 10(-4) and (7.0 ± 3.6) × 10(-3) d L(-1) for (85)Sr, (131)I, (137)Cs, (210)Po, (210)Pb and (238)U, respectively. The biological half-lives were estimated to be 6.4, 4.2, 8.9, and 53.3 days for (85)Sr, (131)I, (137)Cs, and (238)U, respectively. Estimates of the half-lives were based on a one component model: it was found that the half-life values measured for artificial radionuclides were slightly shorter than those for natural radionuclides. The data obtained in the study are the first published experimental data on radionuclide transfer to camel milk. PMID:24508949

  3. Radionuclide transfer from feed to camel milk.

    PubMed

    Al-Masri, M S; Al-Hamwi, A; Amin, Y; Safieh, M B; Zarkawi, M; Soukouti, A; Dayyoub, R; Voigt, G; Fesenko, S

    2014-06-01

    The transfer of (137)Cs, (85)Sr, (131)I, (210)Po, (210)Pb and (238)U from feed to camel's milk was investigated in a pilot experiment with three lactating camels. For a period of 60 days, the animals were fed on spiked feed containing the studied radionuclides. They were subsequently returned to a contamination-free diet and monitored for another 90 days. The activity concentrations of (137)Cs, (85)Sr and (131)I in milk decreased with time and reached background levels after 20 days. Equilibrium transfer coefficients and biological half-lives were estimated and transfer coefficients were calculated as (8.1 ± 3.6) × 10(-4), (4.4 ± 1.6) × 10(-2), (7.8 ± 3.9) × 10(-4), (2.7 ± 3.5) × 10(-4), (1.8 ± 1.5) × 10(-4) and (7.0 ± 3.6) × 10(-3) d L(-1) for (85)Sr, (131)I, (137)Cs, (210)Po, (210)Pb and (238)U, respectively. The biological half-lives were estimated to be 6.4, 4.2, 8.9, and 53.3 days for (85)Sr, (131)I, (137)Cs, and (238)U, respectively. Estimates of the half-lives were based on a one component model: it was found that the half-life values measured for artificial radionuclides were slightly shorter than those for natural radionuclides. The data obtained in the study are the first published experimental data on radionuclide transfer to camel milk.

  4. Radionuclide bone scintigraphy in pediatric orthopedics

    SciTech Connect

    Conway, J.J.

    1986-12-01

    Radionuclide bone scintigraphy is highly sensitive and specific for diagnosing the musculoskeletal disorders of childhood. Conditions such as neonatal osteomyelitis, septic arthritis, diskitis of childhood, Legg-Calve-Perthes disease, the osteochondroses, the toddler's fracture, sports injuries, spondylolysis, myositis ossificians, and reflex sympathetic dystrophy are readily defined. High-quality state-of-the-art scintigraphy is essential in infants and young children. 64 references.

  5. Concrete Property and Radionuclide Migration Tests

    SciTech Connect

    Wellman, Dawn M.; Mattigod, Shas V.; Powers, Laura; Parker, Kent E.; Clayton, Libby N.; Wood, Marcus I.

    2008-10-01

    The Waste Management Project provides safe, compliant, and cost-effective waste management services for the Hanford Site and the DOE Complex. Part of theses services includes safe disposal of LLW and MLLW at the Hanford Low-Level Waste Burial Grounds (LLBG) in accordance with the requirements listed in DOE Order 435.1, Radioactive Waste Management. To partially satisfy these requirements, a Performance Assessment (PA) analyses were completed and approved. DOE Order 435.1 also requires that continuing data collection be conducted to enhance confidence in the critical assumptions used in these analyses to characterize the operational features of the disposal facility that are relied upon to satisfy the performance objectives identified in the Order. One critical assumption is that concrete will frequently be used as waste form or container material to control and minimize the release of radionuclide constituents in waste into the surrounding environment. Data was collected to (1) quantify radionuclide migration through concrete materials similar to those used to encapsulate waste in the LLBG, (2) measure the properties of the concrete materials, especially those likely to influence radionuclide migration, and (3) quantify the stability of U-bearing solid phases of limited solubility in concrete.

  6. [Biosorption of Radionuclide Uranium by Deinococcus radiodurans].

    PubMed

    Yang, Jie; Dong, Fa-qin; Dai, Qun-wei; Liu, Ming-xue; Nie, Xiao-qin; Zhang, Dong; Ma, Jia-lin; Zhou, Xian

    2015-04-01

    As a biological adsorbent, Living Deinococcus radiodurans was used for removing radionuclide uranium in the aqueous solution. The effect factors on biosorption of radionuclide uranium were researched in the present paper, including solution pH values and initial uranium concentration. Meanwhile, the biosorption mechanism was researched by the method of FTIR and SEM/EDS. The results show that the optimum conditions for biosorption are as follows: pH = 5, co = 100 mg · L(-1) and the maximum biosorption capacity is up to 240 mgU · g(-1). According to the SEM results and EDXS analysis, it is indicated that the cell surface is attached by lots of sheet uranium crystals, and the main biosorpiton way of uranium is the ion exchange or surface complexation. Comparing FTIR spectra and FTIR fitting spectra before and after biosorption, we can find that the whole spectra has a certain change, particularly active groups (such as amide groups of the protein, hydroxy, carboxyl and phosphate group) are involved in the biosorption process. Then, there is a new peak at 906 cm(-1) and it is a stretching vibration peak of UO2(2+). Obviously, it is possible that as an anti radiation microorganism, Deinococcus radiodurans could be used for removing radionuclide uranium in radiation environment.

  7. Sorption of radionuclides on Yucca Mountain tuffs

    SciTech Connect

    Meijer, A.; Triay, I.; Knight, S.; Cisneros, M.

    1989-11-01

    A substantial database of sorption coefficients for important radionuclides on Yucca Mountain tuffs has been obtained by Los Alamos National Laboratory over the past ten years. Current sorption studies are focussed on validation questions and augmentation of the existing database. Validation questions concern the effects of the use of crushed instead of solid rock samples in the batch experiments, the use of oversaturated stock solutions, and variations in water/rock ratios. Sorption mechanisms are also being investigated. Database augmentation activities include determination of sorption coefficients for elements with low sorption potential, sorption on psuedocolloids, sorption on fracture lining minerals, and sorption kinetics. Sorption can provide an important barrier to the potential migration of radionuclides from the proposed repository within Yucca Mountain to the accessible environment. In order to quantify this barrier, sorption coefficients appropriate for the Yucca Mountain groundwater system must be obtained for each of the important radionuclides in nuclear waste. Los Alamos National Laboratories has conducted numerous batch (crushed-rock) sorption experiments over the past ten years to develop a sorption coefficient database for the Yucca Mountain site. In the present site characterization phase, the main goals of the sorption test program will be to validate critical sorption coefficients and to augment the existing database where important data are lacking. 11 refs., 1 fig., 3 tabs.

  8. UPTAKE OF RADIONUCLIDE METALS BY SPME FIBERS

    SciTech Connect

    Duff, M; S Crump, S; Robert02 Ray, R; Keisha Martin, K; Donna Beals, D

    2006-08-28

    The Federal Bureau of Investigation (FBI) Laboratory currently does not have on site facilities for handling radioactive evidentiary materials and there are no established FBI methods or procedures for decontaminating high explosive (HE) and fire debris (FD) evidence while maintaining evidentiary value. One experimental method for the isolation of HE and FD residue involves using solid phase microextraction or SPME fibers to remove residue of interest. Due to their high affinity for organics, SPME fibers should have little affinity for most metals. However, no studies have measured the affinity of radionuclides for SPME fibers. The focus of this research was to examine the affinity of dissolved radionuclide ({sup 239/240}Pu, {sup 238}U, {sup 237}Np, {sup 85}Sr, {sup 133}Ba, {sup 137}Cs, {sup 60}Co and {sup 226}Ra) and stable radionuclide surrogate metals (Sr, Co, Ir, Re, Ni, Ba, Cs, Nb, Zr, Ru, and Nd) for SPME fibers at the exposure conditions that favor the uptake of HE and FD residues. Our results from radiochemical and mass spectrometric analyses indicate these metals have little measurable affinity for these SPME fibers during conditions that are conducive to HE and FD residue uptake with subsequent analysis by liquid or gas phase chromatography with mass spectrometric detection.

  9. Radionuclide transport and retardation in tuff

    SciTech Connect

    Vine, E.N.; Bayhurst, B.P.; Daniels, W.R.; DeVilliers, S.J.; Erdal, B.R.; Lawrence, F.O.; Wolfsberg, K.

    1980-12-31

    Batch measurements provide an understanding of which experimental variables are important. For example, sorption ratios vary little with particle size (and surface area); however, groundwater composition and rock composition are quite important. A general correlation has been identified between mineralogy (major phases) and degree of sorption for strontium, cesium, and barium. Although these are approximate, a more detailed analysis may be possible as more samples are studied and the data base increased. Data from crushed tuff columns indicate that, except in simple cases where sorption coefficients are relatively low, and ion-exchange equilibria not only exist but are the dominant mechanism for removal of radioisotopes from solution, the simple relation between the sorption ratio R/sub d/ (or K/sub d/) and the relative velocity of radionuclides with respect to groundwater velocity may be insufficient to permit accurate modeling of the retardation of radionuclides. Additional work on whole core columns and larger blocks of intact material is required to better understand radionuclide sorption and transport through rock.

  10. Targeted radionuclide therapies for pancreatic cancer.

    PubMed

    Shah, M; Da Silva, R; Gravekamp, C; Libutti, S K; Abraham, T; Dadachova, E

    2015-08-01

    Pancreatic malignancies, the fourth leading cause of cancer deaths, have an aggressive behavior with poor prognosis, resulting in a 5-year survival rate of only 4%. It is typically a silent malignancy until patients develop metastatic disease. Targeted radionuclide therapies of cancer such as radiolabeled peptides, which bind to the receptors overexpressed by cancer cells and radiolabeled antibodies to tumor-specific antigens provide a viable alternative to chemotherapy and external beam radiation of metastatic cancers. Multiple clinical trials of targeted radionuclide therapy of pancreatic cancer have been performed in the last decade and demonstrated safety and potential efficacy of radionuclide therapy for treatment of this formidable disease. Although a lot of progress has been made in treatment of pancreatic neuroendocrine tumors with radiolabeled (90)Y and (177)Lu somatostatin peptide analogs, pancreatic adenocarcinomas remain a major challenge. Novel approaches such as peptides and antibodies radiolabeled with alpha emitters, pre-targeting, bispecific antibodies and biological therapy based on the radioactive tumorlytic bacteria might offer a potential breakthrough in treatment of pancreatic adenocarcinomas.

  11. Radionuclide imaging in myocardial sarcoidosis. Demonstration of myocardial uptake of /sup 99m/Tc pyrophosphate and gallium

    SciTech Connect

    Forman, M.B.; Sandler, M.P.; Sacks, G.A.; Kronenberg, M.W.; Powers, T.A.

    1983-03-01

    A patient had severe congestive cardiomyopathy secondary to myocardial sarcoidosis. The clinical diagnosis was confirmed by radionuclide ventriculography, /sup 201/Tl, /sup 67/Ga, and /sup 99m/Tc pyrophosphate (TcPYP) scintigraphy. Myocardial TcPYP uptake has not been reported previously in sarcoidosis. In this patient, TcPYP was as useful as gallium scanning and thallium imaging in documenting the myocardial process.

  12. Radionuclide Partitioning in an Underground Nuclear Test Cavity

    SciTech Connect

    Rose, T P; Hu, Q; Zhao, P; Conrado, C L; Dickerson, R; Eaton, G F; Kersting, A B; Moran, J E; Nimz, G; Powell, B A; Ramon, E C; Ryerson, F J; Williams, R W; Wooddy, P T; Zavarin, M

    2009-01-09

    In 2004, a borehole was drilled into the 1983 Chancellor underground nuclear test cavity to investigate the distribution of radionuclides within the cavity. Sidewall core samples were collected from a range of depths within the re-entry hole and two sidetrack holes. Upon completion of drilling, casing was installed and a submersible pump was used to collect groundwater samples. Test debris and groundwater samples were analyzed for a variety of radionuclides including the fission products {sup 99}Tc, {sup 125}Sb, {sup 129}I, {sup 137}Cs, and {sup 155}Eu, the activation products {sup 60}Co, {sup 152}Eu, and {sup 154}Eu, and the actinides U, Pu, and Am. In addition, the physical and bulk chemical properties of the test debris were characterized using Scanning Electron Microscopy (SEM) and Electron Microprobe measurements. Analytical results were used to evaluate the partitioning of radionuclides between the melt glass, rubble, and groundwater phases in the Chancellor test cavity. Three comparative approaches were used to calculate partitioning values, though each method could not be applied to every nuclide. These approaches are based on: (1) the average Area 19 inventory from Bowen et al. (2001); (2) melt glass, rubble, and groundwater mass estimates from Zhao et al. (2008); and (3) fission product mass yield data from England and Rider (1994). The U and Pu analyses of the test debris are classified and partitioning estimates for these elements were calculated directly from the classified Miller et al. (2002) inventory for the Chancellor test. The partitioning results from this study were compared to partitioning data that were previously published by the IAEA (1998). Predictions of radionuclide distributions from the two studies are in agreement for a majority of the nuclides under consideration. Substantial differences were noted in the partitioning values for {sup 99}Tc, {sup 125}Sb, {sup 129}I, and uranium. These differences are attributable to two factors

  13. Pacific Northwest National Laboratory Site Radionuclide Air Emissions Report for Calendar Year 2011

    SciTech Connect

    Snyder, Sandra F.; Barnett, J. Matthew; Bisping, Lynn E.

    2012-06-12

    This report documents radionuclide air emissions that result in the highest effective dose equivalent (EDE) to a member of the public, referred to as the maximally exposed individual (MEI). The report has been prepared in compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities and Washington Administrative Code (WAC) Chapter 246-247, Radiation ProtectionAir Emissions. The EDE to the PNNL Site MEI due to routine emissions in 2011 from PNNL Site sources was 1.7E 05 mrem (1.7E-7 mSv) EDE. No nonroutine emissions occurred in 2011. The total radiological dose for 2011 to the MEI from all PNNL Site radionuclide emissions was more than 10,000 times smaller than the federal and state standard of 10 mrem/yr, to which the PNNL Site is in compliance.

  14. Pacific Northwest National Laboratory Campus Radionuclide Air Emissions Report for Calendar Year 2013

    SciTech Connect

    Snyder, Sandra F.; Barnett, J. Matthew; Bisping, Lynn E.

    2014-06-01

    This report documents radionuclide air emissions that result in the highest effective dose equivalent (EDE) to a member of the public, referred to as the maximally exposed individual (MEI). The report has been prepared in compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities and Washington Administrative Code (WAC) Chapter 246-247, Radiation Protection Air Emissions. The dose to the PNNL Site MEI due to routine major and minor point source emissions in 2013 from PNNL Site sources is 2E-05 mrem (2E-07 mSv) EDE. The dose from fugitive emissions (i.e., unmonitored sources) is 2E-6 mrem (2E-8 mSv) EDE. The dose from radon emissions is 1E-11 mrem (1E-13 mSv) EDE. No nonroutine emissions occurred in 2013. The total radiological dose for 2013 to the MEI from all PNNL Site radionuclide emissions, including fugitive emissions and radon, is 2E-5 mrem (2E-7 mSv) EDE, or 100,000 times smaller than the federal and state standard of 10 mrem/yr, to which the PNNL Site is in compliance

  15. Pacific Northwest National Laboratory Site Radionuclide Air Emissions Report for Calendar Year 2012

    SciTech Connect

    Snyder, Sandra F.; Barnett, J. Matthew; Bisping, Lynn E.

    2013-06-06

    This report documents radionuclide air emissions that result in the highest effective dose equivalent (EDE) to a member of the public, referred to as the maximally exposed individual (MEI). The report has been prepared in compliance with the Code of Federal Regulations (CFR), Title 40, Protection of the Environment, Part 61, National Emission Standards for Hazardous Air Pollutants (NESHAP), Subpart H, National Emission Standards for Emissions of Radionuclides Other than Radon from Department of Energy Facilities and Washington Administrative Code (WAC) Chapter 246-247, Radiation Protection Air Emissions. The dose to the PNNL Site MEI due to routine major and minor point source emissions in 2012 from PNNL Site sources is 9E-06 mrem (9E-08 mSv) EDE. The dose from fugitive emissions (i.e., unmonitored sources) is 1E-7 mrem (1E-9 mSv) EDE. The dose from radon emissions is 2E-6 mrem (2E-08 mSv) EDE. No nonroutine emissions occurred in 2012. The total radiological dose for 2012 to the MEI from all PNNL Site radionuclide emissions, including fugitive emissions and radon, is 1E-5 mrem (1E-7 mSv) EDE, or 100,000 times smaller than the federal and state standard of 10 mrem/yr, to which the PNNL Site is in compliance.

  16. Mathematical Simulation of Sediment and Radionuclide Transport in Surface Waters

    SciTech Connect

    ,

    1981-04-01

    The study objective of "The Mathematical Simulation of Sediment and Radionuclide Transport in Surface Waters" is to synthesize and test radionuclide transport models capable of realistically assessing radionuclide transport in various types of surface water bodies by including the sediment-radionuclide interactions. These interactions include radionuclide adsorption by sediment; desorption from sediment into water; and transport, deposition, and resuspension of sorbed radionuclides controlled by the sediment movements. During FY-1979, the modification of sediment and contaminant (radionuclide) transport model, FETRA, was completed to make it applicable to coastal waters. The model is an unsteady, two-dimensional (longitudinal and lateral) model that consists of three submodels (for sediment, dissolved-contaminant, and particulate-contaminant transport), coupled to include the sediment-contaminant interactions. In estuaries, flow phenomena and consequent sediment and radionuclide migration are often three-dimensional in nature mainly because of nonuniform channel cross-sections, salinity intrusion, and lateral-flow circulation. Thus, an unsteady, three-dimensional radionuclide transport model for estuaries is also being synthesized by combining and modifying a PNL unsteady hydrothermal model and FETRA. These two radionuclide transport models for coastal waters and estuaries will be applied to actual sites to examine the validity of the codes.

  17. Artificial radionuclides in Russia due to the Fukushima NPP accident

    NASA Astrophysics Data System (ADS)

    Polianskaia, Olga; Vakulovsky, Sergey; Kim, Vera; Yahryushin, Valery; Volokitin, Andrey

    2013-04-01

    conclude that the volumetric activities of radionuclides in the near-the-ground atmospheric layer were by 3 to 6 orders of magnitude below the permissible volume activity set by Radiation Safety Standards of Russia Federation.

  18. Coupled modeling of cement/claystone interactions and radionuclide migration

    NASA Astrophysics Data System (ADS)

    De Windt, L.; Pellegrini, D.; van der Lee, J.

    2004-02-01

    The interactions between cement and a clayey host-rock of an underground repository for intermediate-level radioactive waste are studied with the reactive transport code HYTEC for supporting performance assessment. Care is taken in using relevant time scales (100,000 years) and dimensions. Based on a literature review, three hypotheses are considered with respect to the mineralogical composition of the claystone and the neo-formed phases. In the long term, the pH is buffered for all hypotheses and important mineral transformations occur both in cement and the host-rock. The destruction of the primary minerals is localized close to the cement/claystone interface and is characterized by the precipitation of secondary phases with retention properties (illite, zeolite). However, beyond the zone of intense mineral transformations, the pore water chemistry is also disturbed over a dozen meters due to an attenuated but continuous flux of hydroxyl, potassium and calcium ions. Four interdependent mechanisms control the profile in the whole system: diffusion of the alkaline plume, mineralogical buffering, ion exchange and clogging of the pore space at the cement/claystone interface. The migration of a selected group of radionuclides (Cs, Ra, Tc and U) is explicitly integrated in the simulations of the strongly coupled system. Theoretical profiles of distribution coefficient (Kd) and solubility limit values are derived from the simulations, and their sensitivity with respect to the system evolution is estimated.

  19. Standardizing Immunohistochemistry

    PubMed Central

    Sompuram, Seshi R.; Vani, Kodela; Tracey, Brian; Kamstock, Debra A.

    2015-01-01

    A new standardized immunohistochemistry (IHC) control for breast cancer testing comprises formalin-fixed human epidermal growth factor receptor 2, estrogen receptor, or progesterone receptor peptide antigens covalently attached to 8-µm glass beads. The antigen-coated beads are suspended in a liquid matrix that hardens upon pipetting onto a glass microscope slide. The antigen-coated beads remain in place through deparaffinization, antigen retrieval, and immunostaining. The intensity of the beads’ stain provides feedback regarding the efficacy of both antigen retrieval and immunostaining. As a first report, we tested the sensitivity and specificity of the new IHC controls (“IHControls”). To evaluate sensitivity, various staining problems were simulated. IHControls detected primary and secondary reagent degradation similarly to tissue controls. This first group of IHControls behaved similarly to tissue controls expressing high concentrations of the antigen. The IHControls were also able to detect aberrations in antigen retrieval, as simulated by sub-optimal times or temperatures. Specificity testing revealed that each antigen-coated bead was specific for its cognate IHC test antibody. The data support the conclusion that, like tissue controls, IHControls are capable of verifying the analytic components of an immunohistochemical stain. Unlike tissue controls, IHControls are prepared in large bulk lots, fostering day-to-day reproducibility that can be standardized across laboratories. PMID:25940339

  20. New Federal Air Quality Standards.

    ERIC Educational Resources Information Center

    Stopinski, O. W.

    The report discusses the current procedures for establishing air quality standards, the bases for standards, and, finally, proposed and final National Primary and Secondary Ambient Air Quality Standards for sulfur dioxide, particulate matter, carbon monoxide, nonmethane hydrocarbons, photochemical oxidants, and nitrogen dioxide. (Author/RH)

  1. Identification and quantification of radionuclides in contaminated drinking waters and pipeline deposits.

    PubMed

    Warwick, Phil E; Croudace, Ian W

    2013-09-01

    There is broad international interest, particularly with Homeland Security and first-responder organizations, in developing a range of effective, robust, and rapid analytical tools to identify terrorist assaults. Accidental or intentional radionuclide contamination of drinking water supplies would have significant public health, social, political, and financial implications even where the real risk might be small given public perception. Rapid identification and assessment of the magnitude of any contamination is critical in managing any threat and ultimately in allaying public and regulator concerns and in steering subsequent remediation operations. Conventional screening techniques do not provide information of the radionuclide present, and subsequent identification techniques are too time-consuming and require some prior knowledge of the nuclide identity to permit accurate quantification. The development described here presents a novel, rapid, and effective radiometric approach using industry-standard liquid scintillation counting equipment that can both identify and quantify alpha and beta radionuclide contamination within 1 h of sample receipt. The liquid scintillation counting (LSC) or liquid scintillation analysis (LSA) method, though widely used by the life science and the (14)C scientific communities since the 1960s, has greater potential than is often used. The technique developed here, which uses multiple quench parameters for nuclide identification, has been tested on both contaminated drinking waters and pipeline scales with compositions typical of those that might be encountered. It is shown to be highly effective both in terms of rapidly identifying the radionuclide and providing a measure of the quantity of radionuclide present. The whole procedure is about to be developed into an integrated analytical system for use by untrained personnel. It is notable that the development could also be readily applied as a QC procedure in routine radioanalytical

  2. Evaluation of Subsurface Radionuclide Transport at Commercial Nuclear Power Production Facilities

    NASA Astrophysics Data System (ADS)

    Rasmussen, T. C.; Bollinger, J. S.

    2006-05-01

    An American Nuclear Society (ANS) working group was recently established to revise ANSI/ANS-2.17, a standard for evaluating radionuclide transport in ground water at commercial nuclear power production (NPP) facilities. The working group consists of technical experts from the nuclear industry, Federal and State regulatory agencies, universities, DOE National Laboratories, and hydrogeologic consulting firms. ANS 2.17 was originally adopted in 1980, reaffirmed in 1990, but subsequently withdrawn in 2000 due to a lapse in the decadal concurrence process. The working group charge is to re-visit the lapsed standard, review the state-of-the-science and -practice, and develop a performance-based standard that provides guidelines for demonstrating the ability to detect, characterize, diagnose, quantify, and effectively mitigate accidental and routine subsurface releases of radionuclides from NPP facilities. The resulting consensus standard focuses on subsurface site characterization, monitoring, and modeling issues at NPP sites that will guide the siting and evaluation of radionuclide transport at both existing and proposed new NPP facilities. This presentation provides the technical background for developing the standard along with a description of its current status. Performance Assessment is the proposed framework for designing characterization, monitoring, and modeling programs that quantitatively evaluate release scenarios. Geographic Information Systems (GIS) are proposed for the archival and retrieval of spatially-explicit data, and will include real-time designators. New monitoring technologies are identified that may aid in the detection and characterization of releases. Remediation activities in response to detected releases should reflect, in part, the expected risk as defined using response thresholds. The presenters are actively soliciting technical documents and field application experiences which may contribute to the standard's technical bases and

  3. Below Regulatory Concern Owners Group: Radionuclide characterization of potential BRC waste types from nuclear power stations: Final report

    SciTech Connect

    Robertson, D.E.; Thomas, C.W.; Hetzer, D.C.; Wynhoff, N.L.; Raney, P.J.; Forsythe, J.D.; Schmitt, J.S.; Buschbom, R.L.; Hara, K.T.; Strebin, R.S.

    1989-03-01

    The objective of this study was to perform a detailed radiological characterization and statistical assessment of the measured radionuclide distributions for four candidate ''below regulatory concern'' (BRC) waste types from commercial nuclear power stations. These measurements and statistical evaluations will provide the bases for conducting detailed dose assessments associated with various disposal options for BRC wastes. The four waste types selected were dry active waste (DAW), oil, soil, and secondary side ion exchange resin. The measurement included gamma-spectrometric analyses of 558 total samples, including 102 DAW samples, 231 oil samples, 142 soil samples, and 83 resin samples. Radionuclides usually detected during the gamma spectrometry included /sup 60/Co, /sup 137/Cs, /sup 134/Cs, /sup 54/Mn, and /sup 58/Co. Frequently, /sup 95/Zr, /sup 95/Nb, /sup 106/Ru, and /sup 125/Sb were detected, especially in wastes from plants which had experienced a relatively high rate of fuel cladding failures. Selected aliquots of the gamma-counted samples were radiochemically analyzed for /sup 14/C, /sup 55/Fe, /sup 63/Ni, /sup 90/Sr, /sup 129/I, /sup 238/Pu, and /sup 239,240/Pu. The gamma-emitting radionuclides in the BRC wastes, which are the primary contributors to the limiting dose to the general population for BRC waste disposal, were dominated by /sup 60/Co and /sup 137/Cs. The variability in the major gamma-emitting nuclides was assessed as a function of reactor type and waste stream. A similar evaluation was conducted for the difficult-to-measure radionuclides. From these assessments, it was concluded that the variability in radionuclide composition from all waste streams and all plants was sufficiently small to justify the development of a single, conservative radionuclide composition that would be representative of the BRC waste generated at commercial US nuclear power stations.

  4. Standards not that standard.

    PubMed

    Vilanova, Cristina; Tanner, Kristie; Dorado-Morales, Pedro; Villaescusa, Paula; Chugani, Divya; Frías, Alba; Segredo, Ernesto; Molero, Xavier; Fritschi, Marco; Morales, Lucas; Ramón, Daniel; Peña, Carlos; Peretó, Juli; Porcar, Manuel

    2015-01-01

    There is a general assent on the key role of standards in Synthetic Biology. In two consecutive letters to this journal, suggestions on the assembly methods for the Registry of standard biological parts have been described. We fully agree with those authors on the need of a more flexible building strategy and we highlight in the present work two major functional challenges standardization efforts have to deal with: the need of both universal and orthogonal behaviors. We provide experimental data that clearly indicate that such engineering requirements should not be taken for granted in Synthetic Biology. PMID:26435739

  5. Innovative methodology for intercomparison of radionuclide calibrators using short half-life in situ prepared radioactive sources

    SciTech Connect

    Oliveira, P. A.; Santos, J. A. M.

    2014-07-15

    Purpose: An original radionuclide calibrator method for activity determination is presented. The method could be used for intercomparison surveys for short half-life radioactive sources used in Nuclear Medicine, such as{sup 99m}Tc or most positron emission tomography radiopharmaceuticals. Methods: By evaluation of the resulting net optical density (netOD) using a standardized scanning method of irradiated Gafchromic XRQA2 film, a comparison of the netOD measurement with a previously determined calibration curve can be made and the difference between the tested radionuclide calibrator and a radionuclide calibrator used as reference device can be calculated. To estimate the total expected measurement uncertainties, a careful analysis of the methodology, for the case of{sup 99m}Tc, was performed: reproducibility determination, scanning conditions, and possible fadeout effects. Since every factor of the activity measurement procedure can influence the final result, the method also evaluates correct syringe positioning inside the radionuclide calibrator. Results: As an alternative to using a calibrated source sent to the surveyed site, which requires a relatively long half-life of the nuclide, or sending a portable calibrated radionuclide calibrator, the proposed method uses a source preparedin situ. An indirect activity determination is achieved by the irradiation of a radiochromic film using {sup 99m}Tc under strictly controlled conditions, and cumulated activity calculation from the initial activity and total irradiation time. The irradiated Gafchromic film and the irradiator, without the source, can then be sent to a National Metrology Institute for evaluation of the results. Conclusions: The methodology described in this paper showed to have a good potential for accurate (3%) radionuclide calibrators intercomparison studies for{sup 99m}Tc between Nuclear Medicine centers without source transfer and can easily be adapted to other short half-life radionuclides.

  6. 21 CFR 892.1420 - Radionuclide test pattern phantom.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1420 Radionuclide test pattern phantom... performance characteristic of a nuclear medicine imaging device. (b) Classification. Class I (general...

  7. 21 CFR 892.1420 - Radionuclide test pattern phantom.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1420 Radionuclide test pattern phantom... performance characteristic of a nuclear medicine imaging device. (b) Classification. Class I (general...

  8. 21 CFR 892.1420 - Radionuclide test pattern phantom.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1420 Radionuclide test pattern phantom... performance characteristic of a nuclear medicine imaging device. (b) Classification. Class I (general...

  9. 21 CFR 892.1420 - Radionuclide test pattern phantom.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1420 Radionuclide test pattern phantom... performance characteristic of a nuclear medicine imaging device. (b) Classification. Class I (general...

  10. Selected radionuclides important to low-level radioactive waste management

    SciTech Connect

    1996-11-01

    The purpose of this document is to provide information to state representatives and developers of low level radioactive waste (LLW) management facilities about the radiological, chemical, and physical characteristics of selected radionuclides and their behavior in the environment. Extensive surveys of available literature provided information for this report. Certain radionuclides may contribute significantly to the dose estimated during a radiological performance assessment analysis of an LLW disposal facility. Among these are the radionuclides listed in Title 10 of the Code of Federal Regulations Part 61.55, Tables 1 and 2 (including alpha emitting transuranics with half-lives greater than 5 years). This report discusses these radionuclides and other radionuclides that may be significant during a radiological performance assessment analysis of an LLW disposal facility. This report not only includes essential information on each radionuclide, but also incorporates waste and disposal information on the radionuclide, and behavior of the radionuclide in the environment and in the human body. Radionuclides addressed in this document include technetium-99, carbon-14, iodine-129, tritium, cesium-137, strontium-90, nickel-59, plutonium-241, nickel-63, niobium-94, cobalt-60, curium -42, americium-241, uranium-238, and neptunium-237.

  11. Transuranic radionuclides from resuspension in the environment, a bibliography

    SciTech Connect

    Stoker, A.C.; Shinn, J.H.; Noshkin, V.E.

    1994-04-01

    The purpose of this project was to compile a bibliography of references containing environmental transuranic radionuclide data. Our intent was to identify those parameters affecting transuranic radionuclide transport that may be generic and those that may be dependent on chemical form and/or environmental conditions. An understanding of the unique characteristics and similarities between source terms and environmental conditions relative to transuranic radionuclide transport and cycling will provide the ability to assess and predict the long term impact on man and the environment. An additional goal of our literature review, was to extract the ranges of environmental transuranic radionuclide data from the identified references for inclusion in a data base. Related to source term, these ranges of data can be used to calculate the dose to man from the radionuclides, and to perform uncertainty analyses on these dose assessments. On the basis of our reviews, we have arbitrarily outlined five general source terms. These are fallout, fuel cycle waste, accidents, disposal sites and resuspension. Resuspension of the transuranic radionuclides is an unique source term, in that the radionuclides can originate from any of the other source terms. If these transuranic radionuclides become resuspended into the air, they then become important as a source of inhaled radionuclides. This bibliography is a compilation of the references containing studies of plutonium and americium in the environment as a result of resuspension.

  12. Transuranic radionuclides dispersed into the aquatic environment, a bibliography

    SciTech Connect

    Noshkin, V.E.; Stoker, A.C.; Wong, Kai M.

    1994-04-01

    The purpose of this project was to compile a bibliography of references containing environmental transuranic radionuclide data. Our intent was to identify those parameters affecting transuranic radionuclide transport that may be generic and those that may be dependent on chemical form and/or environmental conditions (i.e., site specific) in terrestrial, aquatic and atmospheric environments An understanding of the unique characteristics and similarities between source terms and environmental conditions relative to transuranic radionuclide transport and cycling will provide the ability to assess and predict the long term impact on man and the environment. An additional goal of our literature review, was to extract the ranges of environmental transuranic radionuclide data from the identified references for inclusion in a data base. Related to source term, these ranges of data can be used to calculate the dose to man from the radionuclides, and to perform uncertainty analyses on these dose assessments. On the basis of our reviews, we have arbitrarily outlined five general source terms. These are fallout, fuel cycle waste, accidents, disposal sites and resuspension. Resuspension of the transuranic radionuclides is a unique source term, in that the radionuclides can originate from any of the other source terms. If these transuranic radionuclides become resuspended into the air, they then become important as a source of inhaled radionuclides.

  13. [Biological effects of the iodine 131 radionuclide].

    PubMed

    Kasuba, V

    1997-06-01

    Radionuclides released into the biosphere by local sources are added to artificial radionuclides introduced by atmospheric nuclear weapon tests or nuclear accidents. The main polluters are nuclear industry reprocessing plants and nuclear power stations. Other sources are hospitals using radionuclides for diagnostics and therapy. This article presents the effects of radioisotope iodine-131 on a living organism, on the cell and on the genetic material within the cell. Beside the accident iodine-131 contamination, its wide diagnostic and therapeutic application attributes to the total radiation dose. The biological distribution of this radiopharmaceutical in the body depends on the way of use and on the and physical and chemical shape of this radiopharmaceutical. A few minutes after the administration, all iodine ingested or inhaled is rapidly absorbed by blood. The irradiation dose in blood depends on the administered amount of 131I and the fraction passing into the plasma as protein-bound 131I. After entering the organism, iodine mostly accumulates in the thyroid gland. The effect of ionized radiation on living cells are proportional to the dosage of 131I. Intracellular radioactive decay occurs in cytoplasm, in karyoplasm, and in the DNA molecule incorporated fraction. Beside the damage resulting from the deposition of radiation energy, 131I causes biological damage when it decays while the isotope is incorporated into the DNA of human cells. Certain beta/gamma-emitting isotopes such as 131I may be particularly hazardous when incorporated into DNA. Incorporation of radioactively labeled compounds into the DNA leads to highly selective irradiation of the nucleus of the proliferating cells. This produces pronounced biological damage as the genetic material in the cell nucleus constitutes the most radiosensitive target within the cell. PMID:9471970

  14. Visualizing plumes of heavy metals and radionuclides

    NASA Astrophysics Data System (ADS)

    Prigiobbe, V.; Liu, T.; Bryant, S. L.; Hesse, M. A.

    2015-12-01

    The understanding of the transport behaviors in porous media resides on the ability to reproduce fundamental phenomena in a lab setting. Experiments with quasi 2D tanks filled with beads are performed to study physical phenomena induced by chemical and fluid dynamic processes. When an alkaline solution containing heavy metals or radionuclides invades a low pH region, mixing due to longitudinal dispersion induces destabilization of the front forming a fast travelling pulse [1]. When the two fluids travel in parallel, instead, mixing induced by transverse dispersion creates a continuous leakage from the alkaline region into the acidic one forming a fast travelling plume [2] (Figure 1). Impact of these phenomena are on aquifers upon leaking of alkaline fluids, rich in heavy metals and radionuclides, from waste storage sites. Here, we report the results from a study where experiments with a quasi 2D tank are performed to analyze the effect of transverse mixing on strontium (Sr2+) transport. To visualize the leaking plume, a fluorescent dye (Fura-2) is added the acidic solution, which has been widely used in biomedical applications [3]. It is the aim of this work to optimize its application under the conditions relevant to this work. Spectrometric measurements of absorption and fluorescence show sensitivity of the dye to the presence of Sr2+ throughout a broad range of pH and Sr2+ concentration (Figure 2). In the absence of Sr2+, no significant absorption and fluorescence was measured, but as Sr2+ was added the relevant peaks increase significantly and sample dilution of tenfold was required to remain within the measuring threshold. These results show a strong sensitivity of the dye to the cation opening the opportunity to use Fura-2 as a tool to visualize heavy metals and radionuclides plumes. References[1] Prigiobbe et al. (2012) GRL 39, L18401. [2] Prigiobbe and Hesse (2015) in preparation. [3] Xu-Friedman and Regehr (2000) J. Neurosci. 20(12) 4414-4422.

  15. Peptide receptor radionuclide therapy: an overview.

    PubMed

    Dash, Ashutosh; Chakraborty, Sudipta; Pillai, Maroor Raghavan Ambikalmajan; Knapp, Furn F Russ

    2015-03-01

    Peptide receptor radionuclide therapy (PRRT) is a site-directed targeted therapeutic strategy that specifically uses radiolabeled peptides as biological targeting vectors designed to deliver cytotoxic levels of radiation dose to cancer cells, which overexpress specific receptors. Interest in PRRT has steadily grown because of the advantages of targeting cellular receptors in vivo with high sensitivity as well as specificity and treatment at the molecular level. Recent advances in molecular biology have not only stimulated advances in PRRT in a sustainable manner but have also pushed the field significantly forward to several unexplored possibilities. Recent decades have witnessed unprecedented endeavors for developing radiolabeled receptor-binding somatostatin analogs for the treatment of neuroendocrine tumors, which have played an important role in the evolution of PRRT and paved the way for the development of other receptor-targeting peptides. Several peptides targeting a variety of receptors have been identified, demonstrating their potential to catalyze breakthroughs in PRRT. In this review, the authors discuss several of these peptides and their analogs with regard to their applications and potential in radionuclide therapy. The advancement in the availability of combinatorial peptide libraries for peptide designing and screening provides the capability of regulating immunogenicity and chemical manipulability. Moreover, the availability of a wide range of bifunctional chelating agents opens up the scope of convenient radiolabeling. For these reasons, it would be possible to envision a future where the scope of PRRT can be tailored for patient-specific application. While PRRT lies at the interface between many disciplines, this technology is inextricably linked to the availability of the therapeutic radionuclides of required quality and activity levels and hence their production is also reviewed.

  16. Research remote laser methods for radionuclides monitoring

    NASA Astrophysics Data System (ADS)

    Kascheev, S. V.; Elizarov, Valentin V.; Grishkanich, Alexander S.; Bespalov, V. G.; Vasil'ev, Sergey K.; Zhevlakov, A. P.

    2014-05-01

    Laser sensing can serve as a highly effective method of searching and monitoring of radioactive contamination. The first method is essence consists in definition the Sr90 and Сs137 concentration by excitation and registration of fluorescence at wavelength of λ = 0.347÷7.0 μm at laser sounding. The second method experiments were carried out under the Raman-scattering circuit. Preliminary results of investigation show the real possibility to register of leakage of a radionuclide with concentration at level of 108÷109 сm-3 on a safe distance from the infected object.

  17. Radionuclide evaluation of nonmalignant bone disorders

    SciTech Connect

    Winzelberg, G.G.

    1983-02-01

    Recent advances in nuclear imaging have improved the noninvasive evaluation of patients with nonmalignant bone disorders. When bone scanning agents are combined with bone marrow scanning agents and gallium-67 scintigraphy, a more accurate diagnosis can be obtained. By selecting the appropriate imaging sequence, it is often possible to distinguish cellulitis from underlying osteomyelitis. In patients with total hip replacements, it may be possible to separate postsurgical changes from prosthetic loosening or infection. Stress fractures in joggers may be detected by radionuclide bone scintigraphy before radiographs become abnormal. These nuclear imaging procedures can be done in most hospitals.

  18. Preparation of radiopharmaceuticals labeled with metal radionuclides

    SciTech Connect

    Welch, M.J.

    1992-06-01

    We recently developed a useful zinc-62/copper-62 generator and are presently evaluating copper-62 radiopharmaceuticals for clinical studies. While developing these copper-62 radiopharmaceuticals, in collaboration with the University of Missouri Research Reactor, Columbia we have also explored copper-64 radiopharmaceuticals. The PET images we obtained with copper-64 tracers were of such high quality that we have developed and evaluated copper-64 labeled antibodies for PET imaging. The major research activities described herein include: the development and assessment of gallium-68 radiopharmaceuticals; the development and evaluation of a new zinc-62/copper-62 generator and the assessment of copper-62 radiopharmaceuticals; mechanistic studies on proteins labeled with metal radionuclides.

  19. Radionuclide partitioning across great lakes natural interfaces

    NASA Astrophysics Data System (ADS)

    Platford, R. F.; Joshi, S. R.

    1989-11-01

    Several water and surface microlayer samples from Lake St. Clair, the Niagara River, and the North Shore of Lake Ontario collected during 1983 1986 have been assayed for a variety of radionuclides. In addition, the foam accumulating in the pool just below Niagara Falls was also analyzed and found to be the most efficient aqueous phase collector of137Cs,210Pb, and226Ra. The order of radioisotope specific activities from highest to lowest is: Lake Ontario sediment, Niagara River suspended solids, Niagara River foam, surface microlayer water, and subsurface water. Radiological dose rates to the sediments from137Cs,226Ra, and228Th total about 5 mGy/y.

  20. Code System for Radionuclide Migration Calculations.

    1988-02-26

    Version: 00 IONMIG is used to calculate the far-field transport of decaying radionuclides through a porous medium by diffusion and convection. It was specifically developed in support of the U. S. Subseabed Disposal program. For user specified velocity and temperature fields the convection-diffusion equation is solved in a sorbing porous medium. The sorption may be a function of species type, concentration, vertical position and local temperature. The formulation used is applicable to two-dimensional planar ormore » axisymmetric geometries. Zero flux conditions are assumed at all but the upper boundaries.« less

  1. Radionuclides at Descartes in the central highlands

    NASA Technical Reports Server (NTRS)

    Wrigley, R. C.

    1973-01-01

    Throium, uranium, potassium, aluminium-26, and sodium-22 were measured by nondestructive gamma ray spectrometry in six soil and two rock samples gathered by Apollo 16 in the lunar central highlands. The soil samples probably include both major geologic formations in the vicinity, the Cayley and Descartes Formations, although it is possible that the Descartes Formation is not represented. The rock samples have low concentrations of primordial radionuclides. The Al concentrations were lower than could be expected from the high abundance of alumina in the Apollo 16 soils reported earlier, but this could be due to lower concentrations of target elements in these soils, sampling depth variations, or regolithic mixing (exposure age variations).

  2. Radionuclides in the Great Lakes basin.

    PubMed

    Ahier, B A; Tracy, B L

    1995-12-01

    The Great Lakes basin is of radiologic interest due to the large population within its boundaries that may be exposed to various sources of ionizing radiation. Specific radionuclides of interest in the basin arising from natural and artificial sources include 3H, 14C, 90Sr, 129I, 131I, 137Cs, 222Rn, 226Ra, 235U, 238U, 239Pu, and 241Am. The greatest contribution to total radiation exposure is the natural background radiation that provides an average dose of about 2.6 mSv/year to all basin residents. Global fallout from atmospheric nuclear weapons tests conducted before 1963 has resulted in the largest input of anthropogenic radioactivity into the lakes. Of increasing importance is the radionuclide input from the various components of the nuclear fuel cycle. Although the dose from these activities is currently very low, it is expected to increase if there is continued growth of the nuclear industry. In spite of strict regulations on design and operation of nuclear power facilities, the potential exists for a serious accident as a result of the large inventories of radionuclides contained in the reactor cores; however, these risks are several orders of magnitude less than the risks from other natural and man-made hazards. An area of major priority over the next few decades will be the management of the substantial amounts of radioactive waste generated by nuclear fuel cycle activities. Based on derived risk coefficients, the theoretical incidence of fatal and weighted nonfatal cancers and hereditary defects in the basin's population, attributable to 50 years of exposure to natural background radiation, is conservatively estimated to be of the order of 3.4 x 10(5) cases. The total number of attributable health effects to the year 2050 from fallout radionuclides in the Great Lakes basin is of the order of 5.0 x 10(3). In contrast, estimates of attributable health effects from 50 years of exposure to current nuclear fuel cycle effluent in the basin are of the order of 2

  3. Radionuclides in the Great Lakes basin.

    PubMed Central

    Ahier, B A; Tracy, B L

    1995-01-01

    The Great Lakes basin is of radiologic interest due to the large population within its boundaries that may be exposed to various sources of ionizing radiation. Specific radionuclides of interest in the basin arising from natural and artificial sources include 3H, 14C, 90Sr, 129I, 131I, 137Cs, 222Rn, 226Ra, 235U, 238U, 239Pu, and 241Am. The greatest contribution to total radiation exposure is the natural background radiation that provides an average dose of about 2.6 mSv/year to all basin residents. Global fallout from atmospheric nuclear weapons tests conducted before 1963 has resulted in the largest input of anthropogenic radioactivity into the lakes. Of increasing importance is the radionuclide input from the various components of the nuclear fuel cycle. Although the dose from these activities is currently very low, it is expected to increase if there is continued growth of the nuclear industry. In spite of strict regulations on design and operation of nuclear power facilities, the potential exists for a serious accident as a result of the large inventories of radionuclides contained in the reactor cores; however, these risks are several orders of magnitude less than the risks from other natural and man-made hazards. An area of major priority over the next few decades will be the management of the substantial amounts of radioactive waste generated by nuclear fuel cycle activities. Based on derived risk coefficients, the theoretical incidence of fatal and weighted nonfatal cancers and hereditary defects in the basin's population, attributable to 50 years of exposure to natural background radiation, is conservatively estimated to be of the order of 3.4 x 10(5) cases. The total number of attributable health effects to the year 2050 from fallout radionuclides in the Great Lakes basin is of the order of 5.0 x 10(3). In contrast, estimates of attributable health effects from 50 years of exposure to current nuclear fuel cycle effluent in the basin are of the order of 2

  4. Method of separating short half-life radionuclides from a mixture of radionuclides

    DOEpatents

    Bray, L.A.; Ryan, J.L.

    1999-03-23

    The present invention is a method of removing an impurity of plutonium, lead or a combination thereof from a mixture of radionuclides that contains the impurity and at least one parent radionuclide. The method has the steps of (a) insuring that the mixture is a hydrochloric acid mixture; (b) oxidizing the acidic mixture and specifically oxidizing the impurity to its highest oxidation state; and (c) passing the oxidized mixture through a chloride form anion exchange column whereupon the oxidized impurity absorbs to the chloride form anion exchange column and the {sup 229}Th or {sup 227}Ac ``cow`` radionuclide passes through the chloride form anion exchange column. The plutonium is removed for the purpose of obtaining other alpha emitting radionuclides in a highly purified form suitable for medical therapy. In addition to plutonium, lead, iron, cobalt, copper, uranium, and other metallic cations that form chloride anionic complexes that may be present in the mixture are removed from the mixture on the chloride form anion exchange column. 8 figs.

  5. Method of separating short half-life radionuclides from a mixture of radionuclides

    DOEpatents

    Bray, Lane A.; Ryan, Jack L.

    1999-01-01

    The present invention is a method of removing an impurity of plutonium, lead or a combination thereof from a mixture of radionuclides that contains the impurity and at least one parent radionuclide. The method has the steps of (a) insuring that the mixture is a hydrochloric acid mixture; (b) oxidizing the acidic mixture and specifically oxidizing the impurity to its highest oxidation state; and (c) passing the oxidized mixture through a chloride form anion exchange column whereupon the oxidized impurity absorbs to the chloride form anion exchange column and the 22.sup.9 Th or 2.sup.27 Ac "cow" radionuclide passes through the chloride form anion exchange column. The plutonium is removed for the purpose of obtaining other alpha emitting radionuclides in a highly purified form suitable for medical therapy. In addition to plutonium; lead, iron, cobalt, copper, uranium, and other metallic cations that form chloride anionic complexes that may be present in the mixture; are removed from the mixture on the chloride form anion exchange column.

  6. Critical review: Radionuclide transport, sediment transport, and water quality mathematical modeling; and radionuclide adsorption/desorption mechanisms

    SciTech Connect

    Onishi, Y.; Serne, R.J.; Arnold, E.M.; Cowan, C.E.; Thompson, F.L.

    1981-01-01

    This report describes the results of a detailed literature review of radionuclide transport models applicable to rivers, estuaries, coastal waters, the Great Lakes, and impoundments. Some representatives sediment transport and water quality models were also reviewed to evaluate if they can be readily adapted to radionuclide transport modeling. The review showed that most available transport models were developed for dissolved radionuclide in rivers. These models include the mechanisms of advection, dispersion, and radionuclide decay. Since the models do not include sediment and radionuclide interactions, they are best suited for simulating short-term radionuclide migration where: (1) radionuclides have small distribution coefficients; (2) sediment concentrations in receiving water bodies are very low. Only 5 of the reviewed models include full sediment and radionuclide interactions: CHMSED developed by Fields; FETRA SERATRA, and TODAM developed by Onishi et al, and a model developed by Shull and Gloyna. The 5 models are applicable to cases where: (1) the distribution coefficient is large; (2) sediment concentrations are high; or (3) long-term migration and accumulation are under consideration. The report also discusses radionuclide absorption/desorption distribution ratios and addresses adsorption/desorption mechanisms and their controlling processes for 25 elements under surface water conditions. These elements are: Am, Sb, C, Ce, Cm, Co, Cr, Cs, Eu, I, Fe, Mn, Np, P, Pu, Pm, Ra, Ru, Sr, Tc, Th, {sup 3}H, U, Zn and Zr.

  7. Cross-bridged Macrocyclic Chelators for Stable Complexation of Copper Radionuclides for PET Imaging

    PubMed Central

    Anderson, Carolyn J.; Wadas, Thaddeus J.; Wong, Edward H.; Weisman, Gary R.

    2015-01-01

    Copper-64 (t1/2 = 12.7 h, β+: 17.4%, Eβ+max = 656 keV; β−: 39%, Eβ-max = 573 keV) has emerged as an important non-standard positron-emitting radionuclide for PET imaging of diseased tissues. A significant challenge of working with copper radionuclides is that they must be delivered to the living system as a stable complex that is attached to a biological targeting molecule for effective imaging and therapy. Significant research has been devoted to the development of ligands that can stably chelate 64Cu, in particular, the cross-bridged macrocyclic chelators. This review describes the coordination chemistry and biological behavior of 64Cu-labeled cross-bridged complexes. PMID:18043536

  8. Characterisation of a radionuclide specific laboratory detector system for the metallurgical industry by Monte Carlo simulations

    NASA Astrophysics Data System (ADS)

    Šolc, Jaroslav; Dryák, Pavel; Moser, Hannah; Branger, Thierry; García-Toraño, Eduardo; Peyrés, Virginia; Tzika, Faidra; Lutter, Guillaume; Capogni, Marco; Fazio, Aldo; Luca, Aurelian; Vodenik, Branko; Oliveira, Carlos; Saraiva, Andre; Szucs, Laszlo; Dziel, Tomasz; Burda, Oleksiy; Arnold, Dirk; Martinkovič, Jozef; Siiskonen, Teemu; Mattila, Aleksi

    2015-11-01

    One of the outputs of the European Metrology Research Programme project "Ionising radiation metrology for the metallurgical industry" (MetroMetal) was a recommendation on a novel radionuclide specific detector system optimised for the measurement of radioactivity in metallurgical samples. The detection efficiency of the recommended system for the standards of cast steel, slag and fume dust developed within the project was characterized by Monte Carlo (MC) simulations performed using different MC codes. Capabilities of MC codes were also tested for simulation of true coincidence summing (TCS) effects for several radionuclides of interest in the metallurgical industry. The TCS correction factors reached up to 32% showing that the TCS effects are of high importance in close measurement geometries met in routine analyses of metallurgical samples.

  9. Traces of natural radionuclides in animal food

    SciTech Connect

    Merli, Isabella Desan; Guazzelli da Silveira, Marcilei A.; Medina, Nilberto H.

    2014-11-11

    Naturally occurring radioactive materials are present everywhere, e.g., in soil, air, housing materials, food, etc. Therefore, human beings and animals receive internal exposure from radioactive elements inside their bodies through breathing and alimentation. Gamma radiation has enough energy to remove an electron from the atom and compromise the rearrangement of electrons in the search for a more stable configuration which can disturb molecule chemical bonding. Food ingestion is one of the most common forms of radioisotopes absorption. The goal of this work is the measurement of natural gamma radiation rates from natural radioisotopes present in animal food. To determine the concentration of natural radionuclides present in animal food gamma-ray spectrometry was applied. We have prepared animal food samples for poultry, fish, dogs, cats and cattle. The two highest total ingestion effective doses observed refers to a sample of mineral salt cattle, 95.3(15) μSv/year, rabbit chow, with a value of 48(5) μSv/year, and cattle mineral salt, with a value of 69(7) μSv/year, while the annual total dose value from terrestrial intake radionuclide is of the order of 290 μSv/year.

  10. Radionuclide complexation in xylem exudates of plants

    SciTech Connect

    Cataldo, D.A.; McFadden, D.M.; Garland, T.R.; Wildung, R.E.

    1985-04-01

    The plant xylem is the primary avenue for transport of nutrient and pollutant elements from the roots of aerial portions of the plant. It is proposed that the transport of reactive or hydrolyzable ions is facilitated by the formation of stable/soluble complexes with organic metabolites. The xylem exudates of soybean (Glycine max cv. Williams) were characterized as to their inorganic and organic components, complexation patterns for radionuclides, both in vivo and in vitro, and for class fractions of exudates using thin-layer electrophoresis. The radionuclides Pu-238 and Fe-59 were found primarily as organic acid complexes, while Ni-63 and Cd-109 were associated primarily with components of the amono acid fraction. Technetium-99 was found to be uncomplexed and transported as the pertechnetate ion. It was not possible to duplicate fully complexes formed in vivo by back reaction with whole exudates or class fractions, indicating the possible importance of plant induction processes, reaction kinetics and/or the formation of mixed ligand complexes. 28 refs., 4 figs.

  11. Treatment planning for molecular targeted radionuclide therapy.

    PubMed

    Siantar, Christine Hartmann; Vetter, Kai; DeNardo, Gerald L; DeNardo, Sally J

    2002-06-01

    Molecular targeted radionuclide therapy promises to expand the usefulness of radiation to successfully treat widespread cancer. The unique properties of radioactive tags make it possible to plan treatments by predicting the radiation absorbed dose to both tumors and normal organs, using a pre-treatment test dose of radiopharmaceutical. This requires a combination of quantitative, high-resolution, radiation-detection hardware and computerized dose-estimation software, and would ideally include biological dose-response data in order to translate radiation absorbed dose into biological effects. Data derived from conventional (external beam) radiation therapy suggests that accurate assessment of the radiation absorbed dose in dose-limiting normal organs could substantially improve the observed clinical response for current agents used in a myeloablative regimen, enabling higher levels of tumor control at lower tumor-to-normal tissue therapeutic indices. Treatment planning based on current radiation detection and simulations technology is sufficient to impact on clinical response. The incorporation of new imaging methods, combined with patient-specific radiation transport simulations, promises to provide unprecedented levels of resolution and quantitative accuracy, which are likely to increase the impact of treatment planning in targeted radionuclide therapy. PMID:12136519

  12. Application of radionuclide ventriculography to cardiac screening

    SciTech Connect

    Lindsay, J. Jr.; Milner, M.R.; Chandeysson, P.L.; Rodman, D.J.; Okin, P.M.; Goldstein, S.A.

    1989-05-01

    Screening asymptomatic individuals for latent coronary disease often requires sequential testing because exercise electrocardiography typically produces more false positive than true positive results in a population with a low prevalence of coronary disease. Cardiac scintigraphy is a technique that may be employed as a confirmatory test in lieu of coronary arteriography to further evaluate the significance of a positive exercise electrocardiogram. Radionuclide ventriculography was employed in 98 asymptomatic individuals who were considered to be at moderate risk of heart disease after risk factor analysis and exercise electrocardiography. Seventeen (17%) patients had an abnormal study and underwent cardiac catheterization. Seven had coronary artery disease, two had cardiomyopathy, and eight were normal. Eighty-one (83%) patients had a normal study. Because the sensitivity of radionuclide ventriculography is 63-80%, it was postulated that 2 to 5 individuals with disease were missed. Thus, from a population with an 11-14% prevalence of disease, two subsets were identified. A large subset in which a prevalence of 2-6% could be estimated was separated from a much smaller one in which a prevalence of approximately 50% was demonstrated.

  13. Traces of natural radionuclides in animal food

    NASA Astrophysics Data System (ADS)

    Merli, Isabella Desan; da Silveira, Marcilei A. Guazzelli; Medina, Nilberto H.

    2014-11-01

    Naturally occurring radioactive materials are present everywhere, e.g., in soil, air, housing materials, food, etc. Therefore, human beings and animals receive internal exposure from radioactive elements inside their bodies through breathing and alimentation. Gamma radiation has enough energy to remove an electron from the atom and compromise the rearrangement of electrons in the search for a more stable configuration which can disturb molecule chemical bonding. Food ingestion is one of the most common forms of radioisotopes absorption. The goal of this work is the measurement of natural gamma radiation rates from natural radioisotopes present in animal food. To determine the concentration of natural radionuclides present in animal food gamma-ray spectrometry was applied. We have prepared animal food samples for poultry, fish, dogs, cats and cattle. The two highest total ingestion effective doses observed refers to a sample of mineral salt cattle, 95.3(15) μSv/year, rabbit chow, with a value of 48(5) μSv/year, and cattle mineral salt, with a value of 69(7) μSv/year, while the annual total dose value from terrestrial intake radionuclide is of the order of 290 μSv/year.

  14. Standardized Curriculum for Cosmetology.

    ERIC Educational Resources Information Center

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized curricula are provided for two courses for the secondary vocational education program in Mississippi: cosmetology I and II. The 18 units in cosmetology I are as follows: introduction to cosmetology; Vocational Industrial Clubs of America; the look you like; bacteriology; sterilization and sanitation; hair and disorders; draping,…

  15. Standardized Curriculum for Electrician.

    ERIC Educational Resources Information Center

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized curricula are provided for two courses for the secondary vocational education program in Mississippi: electrician I and II. The 11 units in electrician I are as follows: orientation; safety; tools, equipment, materials/supplies; basic principles and theory; DC circuits; AC circuits; blueprints and load calculations; load centers and…

  16. Reuse of Material Containing Natural Radionuclides - 12444

    SciTech Connect

    Metlyaev, E.G.; Novikova, N.J.

    2012-07-01

    Disposal of and use of wastes containing natural radioactive material (NORM) or technologically enhanced natural radioactive material (TENORM) with excessive natural background as a building material is very important in the supervision body activity. At the present time, the residents of Octyabrsky village are under resettlement. This village is located just near the Priargunsky mining and chemical combine (Ltd. 'PPGHO'), one of the oldest uranium mines in our country. The vacated wooden houses in the village are demolished and partly used as a building material. To address the issue of potential radiation hazard of the wooden beams originating from demolition of houses in Octyabrsky village, the contents of the natural radionuclides (K-40, Th-232, Ra-226, U- 238) are being determined in samples of the wooden beams of houses. The NORM contents in the wooden house samples are higher, on average, than their content in the reference sample of the fresh wood shavings, but the range of values is rather large. According to the classification of waste containing the natural radionuclides, its evaluation is based on the effective specific activity. At the effective specific activity lower 1.5 kBq/kg and gamma dose rate lower 70 μR/h, the material is not considered as waste and can be used in building by 1 - 3 classes depending upon A{sub eff} value. At 1.5 kBq/kg < A{sub eff} ≤ 4 kBq/kg (4 class), the wooden beams might be used for the purpose of the industrial building, if sum of ratios between the radionuclide specific activity and its specific activity of minimum significance is lower than unit. The material classified as the waste containing the natural radionuclides has A{sub eff} higher 1.5 kBq /kg, and its usage for the purpose of house-building and road construction is forbidden. As for the ash classification and its future usage, such usage is unreasonable, because, according to the provided material, more than 50% of ash samples are considered as radioactive

  17. 14 CFR 25.405 - Secondary control system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Secondary control system. 25.405 Section 25.405 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Control Surface and System Loads § 25.405 Secondary control system. Secondary...

  18. 14 CFR 25.405 - Secondary control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Secondary control system. 25.405 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Control Surface and System Loads § 25.405 Secondary control system. Secondary controls, such as wheel brake, spoiler, and tab controls, must...

  19. Facilitated Strontium Transport by Remobilization of Strontium-Containing Secondary Precipitates in Hanford Site Subsurface

    SciTech Connect

    Wang, Guohui; Um, Wooyong

    2013-03-15

    Significantly enhanced immobilization of radionuclides (such as 90Sr and 137Cs) due to adsorption and coprecipitation with neo-formed colloid-sized secondary precipitates has been reported at the U.S. Department of Energy’s Hanford Site. However, the stability of these secondary precipitates containing radionuclides in the subsurface under changeable field conditions is not clear. Here, the authors tested the remobilization possibility of Sr containing secondary precipitates (nitrate-cancrinite) in the subsurface using saturated column experiments under different geochemical and flow conditions. The columns were packed with quartz sand that contained secondary precipitates (nitrate-cancrinite containing Sr), and leached using colloid-free solutions under different flow rates, varying pH, and ionic strength conditions. The results indicate remobilization of the neo-formed secondary precipitates could be possible given a change of background conditions. The remobility of the neo formed precipitates increased with the rise in the leaching solution flow rate and pH (in a range of pH 4 to 11), as well as with decreasing solution ionic strength. The increased mobility of Sr-containing secondary precipitates with changing background conditions can be a potential source for additional radionuclide transport in Hanford Site subsurface environments.

  20. Sources of anthropogenic radionuclides in the environment: a review.

    PubMed

    Hu, Qin-Hong; Weng, Jian-Qing; Wang, Jin-Sheng

    2010-06-01

    Studies of radionuclides in the environment have entered a new era with the renaissance of nuclear energy and associated fuel reprocessing, geological disposal of high-level nuclear wastes, and concerns about national security with respect to nuclear non-proliferation. This work presents an overview on sources of anthropogenic radionuclides in the environment, as well as a brief discussion of salient geochemical behavior of important radionuclides. We first discuss the following major anthropogenic sources and current developments that have lead, or could potentially contribute, to the radionuclide contamination of the environment: (1) nuclear weapons program; (2) nuclear weapons testing; (3) nuclear power plants; (4) uranium mining and milling; (5) commercial fuel reprocessing; (6) geological repository of high-level nuclear wastes that include radionuclides might be released in the future, and (7) nuclear accidents. Then, we briefly summarize the inventory of radionuclides (99)Tc and (129)I, as well as geochemical behavior for radionuclides (99)Tc, (129)I, and (237)Np, because of their complex geochemical behavior, long half-lives, and presumably high mobility in the environment; biogeochemical cycling and environment risk assessment must take into account speciation of these redox-sensitive radionuclides. PMID:18819734

  1. 21 CFR 892.5650 - Manual radionuclide applicator system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Manual radionuclide applicator system. 892.5650 Section 892.5650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A manual radionuclide applicator system is a manually operated...

  2. Natural Radionuclide Activity Concentrations In Spas Of Argentina

    SciTech Connect

    Gnoni, G.; Czerniczyniec, M.; Canoba, A.; Palacios, M.

    2008-08-07

    Geothermal waters have been used on a large scale for bathing, drinking and medical purposes. These waters can contain natural radionuclides that may increase the exposure to people. In this work the most important natural radionuclide activity concentrations in different thermal spas of Argentina were measured to characterize waters and to evaluate the exposure of workers and members of the public.

  3. Natural Radionuclide Activity Concentrations In Spas Of Argentina

    NASA Astrophysics Data System (ADS)

    Gnoni, G.; Czerniczyniec, M.; Canoba, A.; Palacios, M.

    2008-08-01

    Geothermal waters have been used on a large scale for bathing, drinking and medical purposes. These waters can contain natural radionuclides that may increase the exposure to people. In this work the most important natural radionuclide activity concentrations in different thermal spas of Argentina were measured to characterize waters and to evaluate the exposure of workers and members of the public.

  4. Selection and manipulation of immunoglobulins for radionuclide delivery

    SciTech Connect

    Steplewski, Z.; Curtis, P.; Hainfeld, J.; Mausner, L.; Mease, R.; Srivastava, S.

    1992-12-31

    This report describes a collection of monoclonal antibodies that are candidates for use in radioimmunotherapy towards neoplasms of the gastrointestinal tract, breast, or of astrocytomas. In addition a large series of candidate radionuclides to conjugate to antibodies for therapeutic uses are discussed with respect to potential therapeutic utility and to means of radionuclide production.

  5. 21 CFR 892.1360 - Radionuclide dose calibrator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Radionuclide dose calibrator. 892.1360 Section 892.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1360 Radionuclide dose calibrator....

  6. 21 CFR 892.5740 - Radionuclide teletherapy source.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Radionuclide teletherapy source. 892.5740 Section 892.5740 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5740 Radionuclide teletherapy...

  7. 21 CFR 892.5740 - Radionuclide teletherapy source.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Radionuclide teletherapy source. 892.5740 Section 892.5740 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Therapeutic Devices § 892.5740 Radionuclide teletherapy...

  8. 21 CFR 892.1390 - Radionuclide rebreathing system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Radionuclide rebreathing system. 892.1390 Section 892.1390 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1390 Radionuclide rebreathing...

  9. 21 CFR 892.1360 - Radionuclide dose calibrator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Radionuclide dose calibrator. 892.1360 Section 892.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1360 Radionuclide dose calibrator....

  10. 21 CFR 892.1390 - Radionuclide rebreathing system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Radionuclide rebreathing system. 892.1390 Section 892.1390 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1390 Radionuclide rebreathing...

  11. 21 CFR 892.1390 - Radionuclide rebreathing system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Radionuclide rebreathing system. 892.1390 Section 892.1390 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1390 Radionuclide rebreathing...

  12. 21 CFR 892.5650 - Manual radionuclide applicator system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Manual radionuclide applicator system. 892.5650 Section 892.5650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... intended to apply a radionuclide source into the body or to the surface of the body for radiation...

  13. 21 CFR 892.1360 - Radionuclide dose calibrator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Radionuclide dose calibrator. 892.1360 Section 892.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...) Identification. A radionuclide dose calibrator is a radiation detection device intended to assay...

  14. 21 CFR 892.1360 - Radionuclide dose calibrator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Radionuclide dose calibrator. 892.1360 Section 892.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...) Identification. A radionuclide dose calibrator is a radiation detection device intended to assay...

  15. 21 CFR 892.1360 - Radionuclide dose calibrator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Radionuclide dose calibrator. 892.1360 Section 892.1360 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...) Identification. A radionuclide dose calibrator is a radiation detection device intended to assay...

  16. 21 CFR 892.5750 - Radionuclide radiation therapy system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Radionuclide radiation therapy system. 892.5750 Section 892.5750 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A radionuclide radiation therapy system is a device intended to permit...

  17. 21 CFR 892.5650 - Manual radionuclide applicator system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Manual radionuclide applicator system. 892.5650 Section 892.5650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A manual radionuclide applicator system is a manually operated...

  18. 21 CFR 892.5750 - Radionuclide radiation therapy system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Radionuclide radiation therapy system. 892.5750 Section 892.5750 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A radionuclide radiation therapy system is a device intended to permit...

  19. 21 CFR 892.5650 - Manual radionuclide applicator system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual radionuclide applicator system. 892.5650 Section 892.5650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A manual radionuclide applicator system is a manually operated...

  20. 21 CFR 892.5650 - Manual radionuclide applicator system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Manual radionuclide applicator system. 892.5650 Section 892.5650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A manual radionuclide applicator system is a manually operated...

  1. 21 CFR 892.5750 - Radionuclide radiation therapy system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Radionuclide radiation therapy system. 892.5750 Section 892.5750 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... system. (a) Identification. A radionuclide radiation therapy system is a device intended to permit...

  2. The Changing Work Environment and Skills Standards.

    ERIC Educational Resources Information Center

    Atkinson, June S.

    1997-01-01

    Compares the National Business Education Association's National Standards for Business Education and the Vocational Technical Education Consortium of States' Administrative Support Occupations Skills Standards. Discusses their use in preparing secondary and postsecondary students for the changing workplace. (SK)

  3. Atmospheric radionuclide concentrations measured by Pacific Northwest Laboratory since 1961

    SciTech Connect

    Young, J.A.; Thomas, C.W.

    1981-03-01

    The atmospheric concentrations of a wide spectrum of radionuclides produced by nuclear weapons, nuclear reactors, cosmic rays, radon and thoron decay and the SNAP-9A burn-up ([sup 238]Pu) have been measured at Richland, Washington, since 1961; at Barrow, Alaska, since 1964; and at other stations for shorter periods of time. There has been considerable concern over the health hazard presented by these radionuclides, but it has also been recognized that atmospheric mixing and deposition rates can be determined from their measurement. Therefore, Pacific Northwest Laboratory began the continuous measurement of the atmospheric concentrations of a wide spectrum of radionuclides produced by nuclear weapons, nuclear reactors, cosmic rays, and radon and thoron decay. This report will discuss the concentrations of the longer-lived radionuclides (T 1/2 > 12 days). The concentrations of shorter-lived radionuclides measured following Chinese nuclear tests since 1972 are discussed in another report.

  4. Atmospheric radionuclide concentrations measured by Pacific Northwest Laboratory since 1961

    SciTech Connect

    Young, J.A.; Thomas, C.W.

    1981-03-01

    The atmospheric concentrations of a wide spectrum of radionuclides produced by nuclear weapons, nuclear reactors, cosmic rays, radon and thoron decay and the SNAP-9A burn-up ({sup 238}Pu) have been measured at Richland, Washington, since 1961; at Barrow, Alaska, since 1964; and at other stations for shorter periods of time. There has been considerable concern over the health hazard presented by these radionuclides, but it has also been recognized that atmospheric mixing and deposition rates can be determined from their measurement. Therefore, Pacific Northwest Laboratory began the continuous measurement of the atmospheric concentrations of a wide spectrum of radionuclides produced by nuclear weapons, nuclear reactors, cosmic rays, and radon and thoron decay. This report will discuss the concentrations of the longer-lived radionuclides (T 1/2 > 12 days). The concentrations of shorter-lived radionuclides measured following Chinese nuclear tests since 1972 are discussed in another report.

  5. Quantitative modeling of Cerenkov light production efficiency from medical radionuclides.

    PubMed

    Beattie, Bradley J; Thorek, Daniel L J; Schmidtlein, Charles R; Pentlow, Keith S; Humm, John L; Hielscher, Andreas H

    2012-01-01

    There has been recent and growing interest in applying Cerenkov radiation (CR) for biological applications. Knowledge of the production efficiency and other characteristics of the CR produced by various radionuclides would help in accessing the feasibility of proposed applications and guide the choice of radionuclides. To generate this information we developed models of CR production efficiency based on the Frank-Tamm equation and models of CR distribution based on Monte-Carlo simulations of photon and β particle transport. All models were validated against direct measurements using multiple radionuclides and then applied to a number of radionuclides commonly used in biomedical applications. We show that two radionuclides, Ac-225 and In-111, which have been reported to produce CR in water, do not in fact produce CR directly. We also propose a simple means of using this information to calibrate high sensitivity luminescence imaging systems and show evidence suggesting that this calibration may be more accurate than methods in routine current use.

  6. Radionuclide concentrations in white sturgeon from the Columbia River

    SciTech Connect

    Dauble, D.D.; Price, K.R.; Poston, T.M.

    1992-09-01

    Although radioactive releases from the US Department of Energy`s Hanford Site have been monitored in the environment since the reactors began operating in 1945, recent information regarding historical releases of radionuclides has led to renewed interest in estimating human exposure to radionuclides at Hanford. Knowledge of the fate of radionuclides in some fish species may be important because of the potential for food-chain transfer to humans. White sturgeon (Acipenser transmontanus) were selected for study because they are long-lived, reside year-round in the Hanford Reach, are benthic, and are an important commercial and sport species in the Columbia River. They also have a greater potential for accumulating persistent radionuclides than shorter-lived species with pelagic and/or anadromous life histories. The purpose of our study was to summarize data on historical concentrations of industrial radionuclides in white sturgeon and to collect additional data on current body burdens in the Columbia River.

  7. Radionuclide concentrations in white sturgeon from the Columbia River

    SciTech Connect

    Dauble, D.D.; Price, K.R.; Poston, T.M.

    1992-09-01

    Although radioactive releases from the US Department of Energy's Hanford Site have been monitored in the environment since the reactors began operating in 1945, recent information regarding historical releases of radionuclides has led to renewed interest in estimating human exposure to radionuclides at Hanford. Knowledge of the fate of radionuclides in some fish species may be important because of the potential for food-chain transfer to humans. White sturgeon (Acipenser transmontanus) were selected for study because they are long-lived, reside year-round in the Hanford Reach, are benthic, and are an important commercial and sport species in the Columbia River. They also have a greater potential for accumulating persistent radionuclides than shorter-lived species with pelagic and/or anadromous life histories. The purpose of our study was to summarize data on historical concentrations of industrial radionuclides in white sturgeon and to collect additional data on current body burdens in the Columbia River.

  8. Intravenous radionuclide cystography for the detection of vesicorenal reflux

    SciTech Connect

    Pollet, J.E.; Sharp, P.F.; Smith, F.W.; Davidson, A.I.; Miller, S.S.

    1981-01-01

    Intravenous radionuclide cystography using a single intravenous injection of 99mtechnetium diethylenetriaminepentaacetic acid, provides information on individual kidney function, coarse anatomy and vesicorenal reflux. This study investigates the effectiveness of intravenous radionuclide cystography in detecting reflux. In 58 children intravenous radionuclide cystography detected 53 ureters with reflux compared to 32 detected by voiding cystography. This difference was investigated further with patients in whom other test suggested reflux. While there was no statistically significant difference for patients having pyelonephritis or hydronephrosis, intravenous radionuclide cystography detected significantly more ureters with reflux in patients with abnormal ureteral orifices or infected urine and, therefore, predisposed to reflux. Intravenous radionuclide cystography is a more comprehensive and sensitive test for vesicorenal reflux than voiding cystography.

  9. Accumulation of radionuclides by plants as a monitor system.

    PubMed Central

    Koranda, J J; Robison, W L

    1978-01-01

    The accumulation of radionuclides by plants acting as a monitoring system in the environment may occur by two modes; foliar absorption by the leaves and shoot of the plant, or by root uptake from the soil. Data on plant accumulation of radionuclides may be obtained from studies of fission product radionuclides deposited as worldwide fallout, and from tracer studies of plant physiology. The epidermal features of plant foliage may exert an effect upon particle retention by leaves, and subsequent uptake of radionuclides from the surface. The transport of radionuclides across the cuticle and epidermis of plant leaves is determined in part by the anatomy of the leaf, and by physiological factors. The foliar uptake of fallout radionuclides, 99Sr, 131I, and 137Cs, is described with examples from the scientific literature. The environmental half-life of 131I, for example, is considerably shorter than its physical half-life because of physical and biological factors which may produce a half-life as short as 0.23/day. 99Sr and 137Cs are readily taken up by the leaf, but 137Cs undergoes more translocation into fruit and seeds than 99Sr which tends to remain in the plant part in which it was initially absorbed. Soil-root uptake is conditioned primarily by soil chemical and physical factors which may selectively retain a radionuclide, such as 137Cs. The presence of organic matter, inorganic colloids (clay), and competing elements will strongly affect the uptake of 99Sr and 137Cs by plants from the soil. The role of plants as monitors of radionuclides is twofold: as monitors of recent atmospheric releases of radionuclides; and as indicators of the long-term behavior of aged deposits of radionuclides in the soil. PMID:367767

  10. A limiting factor for the progress of radionuclide-based cancer diagnostics and therapy--availability of suitable radionuclides.

    PubMed

    Tolmachev, Vladimir; Carlsson, Jörgen; Lundqvist, Hans

    2004-01-01

    Advances in diagnostics and targeted radionuclide therapy of haematological and neuroendocrine tumours have raised hope for improved radionuclide therapy of other forms of disseminated tumours. New molecular target structures are characterized and this stimulates the efforts to develop new radiolabelled targeting agents. There is also improved understanding of factors of importance for choice of appropriate radionuclides. The choice is determined by physical, chemical, biological, and economic factors, such as a character of emitted radiation, physical half-life, labelling chemistry, chemical stability of the label, intracellular retention time, and fate of radiocatabolites and availability of the radionuclide. There is actually limited availability of suitable radionuclides and this is a limiting factor for further progress in the field and this is the focus in this article. The probably most promising therapeutic radionuclide, 211At, requires regional production and distribution centres with dedicated cyclotrons. Such centres are, with a few exceptions in the world, lacking today. They can be designed to also produce beta- and Augeremitters of therapeutic interest. Furthermore, emerging satellite PET scanners will in the near future demand long-lived positron emitters for diagnostics with macromolecular radiopharmaceuticals, and these can also be produced at such centres. To secure continued development and to meet the foreseen requirements for radionuclide availability from the medical community it is necessary to establish specialized cyclotron centres for radionuclide production. PMID:15244250

  11. Prospects for the methods of radionuclide production

    NASA Astrophysics Data System (ADS)

    Karamian, S. A.; Dmitriev, S. N.

    2015-03-01

    In the present report, methods of radionuclide production for the nuclear-medicine purposes are described. In a budget approach, the application of low-energy accelerators is especially advantageous. Intense flux of bremsstrahlung at electron accelerators or high-current cyclotron beams of alpha particles must supply a great yield for many isotopes. The choice of a target material and of the projectile energy provides enough variation for concrete species formation. The innovating procedures are here proposed for optimizing of methods, for instance, application of the noble-gas target for production and transport of activities. The known and new variants of the "generator" scheme are discussed. Many isotopes are listed as promising in the context of the therapeutic and theragnostic applications. Among them are isotopes/isomers emitting soft radiation for the selective and careful body treatment, also the positron emitters for PET, and the halogen and alkali-metal species convenient for chemical separation.

  12. Hydroponic phytoremediation of heavy metals and radionuclides

    SciTech Connect

    Hartong, J.; Szpak, J.; Hamric, T.; Cutright, T.

    1998-07-01

    It is estimated that the Departments of Defense, Energy, and Agriculture will spend up to 300 billion federal dollars on environmental remediation during the next century. Current remediation processes can be expensive, non-aesthetic, and non-versatile. Therefore, the need exists for more innovative and cost effective solutions. Phytoremediation, the use of vegetation for the remediation of contaminated sediments, soils, and ground water, is an emerging technology for treating several categories of persistent, toxic contaminants. Although effective, phytoremediation is still in a developmental stage, and therefore is not a widely accepted technology by regulatory agencies and public groups. Research is currently being conducted to validate the processes effectiveness as well as increase regulatory and community acceptance. This research will focus on the ability of plants to treat an aquifer contaminated with heavy metals and radionuclides. Specifically, the effectiveness of hydroponically grown dwarf sunflowers and mustard seed will be investigated.

  13. Radionuclides accumulation in milk and its products

    NASA Astrophysics Data System (ADS)

    Marmuleva, N. I.; Barinov, E. Ya.; Petukhov, V. L.

    2003-05-01

    The problem of radioactive pollution is extremely urgent in Russia in connection with presence of territories polluted by radionuclides on places of nuclear tests, in zones around the enterprises on production, processing and storage of radioactive materials, and also in areas of emergency pollution (Barakhtin, 2001). The aim of our investigation was a determination of the levels of the main radioactive elements - Cs-137 and Sr-90 in diary products. 363 samples of milk, dry milk, butter, cheese and yogurt from Novosibirsk region were examined. Cs-137 level was 3.7...9.2 times higher than Sr-90 one in milk, cheese and yogurt. At the same time the level of these radio nuclides in butter was identical (8.03 Bk/kg).

  14. Radionuclide imaging and treatment of thyroid cancer.

    PubMed

    Wang, Xiu Juan; Li, XianFeng; Ren, Yuan

    2016-01-01

    Over the past decades, the diagnostic methods and therapeutic tools for thyroid cancer (TC) have been greatly improved. In addition to the classical method of ingestion of radioactive iodine-131 (I131) and subsequent I123 and I124 positron emission tomography (PET) in therapy and examination, I124 PET-based 3-dimensional imaging, Ga68-labeled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-NaI(3)-octreotide (DOTANOC) PET/computed tomography (CT), Tc99m tetrofosmin, pre-targeted radioimmunotherapy, and peptide receptor radionuclide therapy have all been used clinically. These novel methods are useful in diagnosis and therapy of TC, but also have unavoidable adverse effects. In this review, we will discuss the development of nuclear medicine in TC examination and treatment. PMID:27100499

  15. Radionuclide cholescintigraphy in genetically confirmed Rotor syndrome.

    PubMed

    Sirucek, Pavel; Sulakova, Astrida; Jirsa, Milan; Mrhac, Lubomir; Havel, Martin; Kraft, Otakar

    2015-10-01

    A 7-year-old girl had been followed up for persistent conjugated hyperbilirubinemia since birth. Alanine aminotransferase, aspartate aminotransferase and γ-glutamyl transpeptidase activity was within the normal range, and liver protein synthesis had always been normal. Infectious etiology of jaundice, autoimmune diseases, drug-induced liver injury, hemolytic anemia, α-1 anti-trypsin deficiency, Wilson disease and Gilbert syndrome were ruled out. At the age of 8 years the patient underwent radionuclide dynamic cholescintigraphy, indicating poor accumulation of the radiotracer in the liver on one hand, and severe retention of the radiopharmaceutical in the blood pool (including the heart) on the other hand. Rotor syndrome was suspected and finally confirmed on molecular analysis. This case represents the first cholescintigraphy report in a pediatric patient with genetically proven Rotor syndrome. PMID:26508179

  16. Prospects for the methods of radionuclide production

    SciTech Connect

    Karamian, S. A. Dmitriev, S. N.

    2015-03-30

    In the present report, methods of radionuclide production for the nuclear-medicine purposes are described. In a budget approach, the application of low-energy accelerators is especially advantageous. Intense flux of bremsstrahlung at electron accelerators or high-current cyclotron beams of alpha particles must supply a great yield for many isotopes. The choice of a target material and of the projectile energy provides enough variation for concrete species formation. The innovating procedures are here proposed for optimizing of methods, for instance, application of the noble-gas target for production and transport of activities. The known and new variants of the “generator” scheme are discussed. Many isotopes are listed as promising in the context of the therapeutic and theragnostic applications. Among them are isotopes/isomers emitting soft radiation for the selective and careful body treatment, also the positron emitters for PET, and the halogen and alkali-metal species convenient for chemical separation.

  17. Cadastral valuation of land contaminated with radionuclides

    NASA Astrophysics Data System (ADS)

    Ratnikov, A. N.; Sapozhnikov, P. M.; Sanzharova, N. I.; Sviridenko, D. G.; Zhigareva, T. L.; Popova, G. I.; Panov, A. V.; Kozlova, I. Yu.

    2016-01-01

    The methodology and procedure for cadastral valuation of land in the areas contaminated with radionuclides are presented. The efficiency of rehabilitation measures applied to decrease crop contamination to the levels satisfying sanitary-hygienic norms is discussed. The differentiation of cadastral value of radioactively contaminated agricultural lands for the particular farms and land plots is suggested. An example of cadastral valuation of agricultural land contaminated during the Chernobyl Nuclear Power Plant accident is given. It is shown that the use of sandy and loamy sandy soddy-podzolic soils with the 137Cs contamination of 37-185 and >185 kBq/m2 for crop growing is unfeasible. The growing of grain crops and potatoes on clay loamy soddy-podzolic soils with the 137Cs contamination of 555-740 kBq/m2 is unprofitable. The maximum cadastral value of radioactively contaminated lands is typical of leached chernozems.

  18. Radionuclide Decay and In-growth Technical Basis Document

    SciTech Connect

    Kersting, A B; Finnegan, D L; Tompson, A F B; Esser, B K; Smith, D K; Zavarin, M; Bruton, C J; Pawloski, G A

    2003-07-01

    The purpose of this report is to assess the decay and in-growth of radionuclides from the radionuclide source term (RST) deposited by underground nuclear weapons tests conducted at the NTS from 1951 through 1992. A priority of the Underground Test Area (UGTA) project, administered by the Environmental Restoration Division of NNSA/NV, was to determine as accurately as possible a measure of the total radionuclide inventory for calculation of the RST deposited in the subsurface at the Nevada Test Site (NTS). The motivation for the development of a total radionuclide inventory is driven by a need to calculate the amount of radioactivity that will move away from the nuclear test cavities over time, referred to as the hydrologic source term (HST). The HST is a subset of the RST and must be calculated using knowledge of the geochemistry and hydrology of the subsurface environment. This will serve the regulatory process designed to protect human health from exposures to contaminated groundwater. Following the detonation of an underground nuclear test, and depending on the presence of water at the location of the detonation, the residual radionuclides may be found in aqueous or gaseous states, precipitated or chemically sorbed states, or incorporated in melt glass produced by the nuclear test. The decay and in-growth of radionuclides may have geochemical implications for the migration of radionuclides away from underground nuclear test cavities. For example, in the case of a long-lived mobile parent decaying to a shorter-lived and less mobile daughter, the geochemical properties of the parent element may control the migration potential of the daughter nuclide. It becomes important to understand the evolution of the RST in terms of effects on the mobility, solubility, or abundance of radionuclides in the HST that are created by decay and in-growth processes. The total radionuclide inventory and thus the RST changes with time due to radioactive decay. The abundance of a

  19. Colloid-Associated Radionuclide Concentration Limits: ANL

    SciTech Connect

    C. Mertz

    2000-12-21

    The purpose and scope of this report is to describe the analysis of available colloidal data from waste form corrosion tests at Argonne National Laboratory (ANL) to extract characteristics of these colloids that can be used in modeling their contribution to the source term for sparingly soluble radioelements (e.g., Pu). Specifically, the focus is on developing a useful description of the following waste form colloid characteristics: (1) composition, (2) size distribution, and (3) quantification of the rate of waste form colloid generation. The composition and size distribution information are intended to support analysis of the potential transport of the sparingly soluble radionuclides associated with the waste form colloids. The rate of colloid generation is intended to support analysis of the waste form colloid-associated radionuclide concentrations. In addressing the above characteristics, available data are interpreted to address mechanisms controlling colloid formation and stability. This report was developed in accordance with the ''Technical Work Plan for Waste Form Degradation Process Model Report for SR'' (CRWMS M&O 2000). Because the end objective is to support the source term modeling we have organized the conclusions into two categories: (1) data analysis conclusions and (2) recommendations for colloid source term modeling. The second category is included to facilitate use of the conclusions from the data analysis in the abstraction of a colloid source term model. The data analyses and conclusions that are presented in this report are based on small-scale laboratory tests conducted on a limited number of waste glass compositions and spent fuel types.

  20. Removal of radionuclides at a waterworks.

    PubMed

    Gäfvert, T; Ellmark, C; Holm, E

    2002-01-01

    A waterworks with an average production rate of 1.3 m3 s(-1), providing several large cities in the province of Scania with drinking water has been studied regarding its capacity to remove several natural and anthropogenic radionuclides. The raw water is surface water from lake Bolmen which is transported through an 80 km long tunnel in the bedrock before it enters the waterworks. The method used for purification is a combination of coagulation-flocculation and filtration in sand filters. Two different purification lines are currently in use, one using Al2(SO4)3 as a coagulant and one using FeCl3. After coagulation and flocculation the precipitate is removed and the water is passed through two different sand filters (rapid filtration and slow filtration). Water samples were collected at the lake, the inlet to the waterworks, after each of the flocculation basins (Al2(SO4)3 and FeCl3), after rapid filtration and from the municipal distribution network. The samples were analysed with respect to their content of uranium, thorium, polonium, radium, plutonium and caesium. The results show a high removal capacity for uranium (about 85%), thorium (>90%), plutonium (>95%) and polonium (>90% in the coagulation-flocculation process) while caesium, strontium and radium pass through the purification process with almost unchanged activity concentrations. During transportation of the water in the tunnel it was also observed that infiltration of groundwater leads to a change in isotopic ratios and/or activity concentrations for the naturally occurring radionuclides and plutonium.