Sample records for section eventually sufficient

  1. Science Directorate Publications and Presentations

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2000-01-01

    This document lists the significant publications and presentation of the Science Directorate during the period January 1-December 31, 1999. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number). Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a section under Open Literature.

  2. Science Directorate Publications and Presentations

    NASA Astrophysics Data System (ADS)

    Summers, F. G.

    2000-07-01

    This document lists the significant publications and presentation of the Science Directorate during the period January 1-December 31, 1999. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number). Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a section under Open Literature.

  3. Oblique nonlinear whistler wave

    NASA Astrophysics Data System (ADS)

    Yoon, Peter H.; Pandey, Vinay S.; Lee, Dong-Hun

    2014-03-01

    Motivated by satellite observation of large-amplitude whistler waves propagating in oblique directions with respect to the ambient magnetic field, a recent letter discusses the physics of large-amplitude whistler waves and relativistic electron acceleration. One of the conclusions of that letter is that oblique whistler waves will eventually undergo nonlinear steepening regardless of the amplitude. The present paper reexamines this claim and finds that the steepening associated with the density perturbation almost never occurs, unless whistler waves have sufficiently high amplitude and propagate sufficiently close to the resonance cone angle.

  4. Electricity storage: Friend or foe of the networks?

    NASA Astrophysics Data System (ADS)

    Jamasb, Tooraj

    2017-06-01

    As storage technology progresses it offers a range of solutions and services to users and the electricity industry. A new study explores whether or not this will eventually lead to self-sufficient consumers and spell the end of the networks as we know them.

  5. Science Directorate Publications and Presentations, January 1 - December 31, 2001

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2002-01-01

    This TM lists the significant publications and presentation of the Science Directorate during the period January 1-December 31, 2001. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a section under Open Literature. Questions or requests for additional information about the entries in this report should be directed to Ann F. Whitaker (SD01; (256) 544-2481) or to one of the authors.

  6. School, Work and Family Planning. Interim Impacts in Project Redirection.

    ERIC Educational Resources Information Center

    Polit, Denise F.; And Others

    Project Redirection was designed to help pregnant and parenting adolescents progress toward eventual self-sufficiency by linking them with community agencies and volunteers at four geographically and ethnically diverse sites in the United States. Distinctive features of the program include: (1) a broad scope of services including employability…

  7. Running Out of Time: Why Elephants Don't Gallop

    NASA Astrophysics Data System (ADS)

    Noble, Julian V.

    2001-11-01

    The physics of high speed running implies that galloping becomes impossible for sufficiently large animals. Some authors have suggested that because the strength/weight ratio decreases with size and eventually renders large animals excessively liable to injury when they attempt to gallop. This paper suggests that large animals cannot move their limbs sufficiently rapidly to take advantage of leaving the ground, hence are restricted to walking gaits. >From this point of view the relatively low strength/weight ratio of elephants follows from their inability to gallop, rather than causing it.

  8. Using Unspent TANF Funds to Further Self-Sufficiency among Welfare Recipients.

    ERIC Educational Resources Information Center

    Copeland, Ivory

    2000-01-01

    The issue of unspent Temporary Assistance for Needy Families (TANF) funds has become increasingly important with the progression of welfare reform. Some support reserving the funds for an eventual economic downturn, whereas others urge investing the funds in services for hard-to-serve welfare recipients and broader low-income participation. States…

  9. Quantum entanglement in three accelerating qubits coupled to scalar fields

    NASA Astrophysics Data System (ADS)

    Dai, Yue; Shen, Zhejun; Shi, Yu

    2016-07-01

    We consider quantum entanglement of three accelerating qubits, each of which is locally coupled with a real scalar field, without causal influence among the qubits or among the fields. The initial states are assumed to be the GHZ and W states, which are the two representative three-partite entangled states. For each initial state, we study how various kinds of entanglement depend on the accelerations of the three qubits. All kinds of entanglement eventually suddenly die if at least two of three qubits have large enough accelerations. This result implies the eventual sudden death of all kinds of entanglement among three particles coupled with scalar fields when they are sufficiently close to the horizon of a black hole.

  10. Novel Technologies for Next Generation Memory

    DTIC Science & Technology

    2013-07-25

    charge in the capacitor) eventually fades unless the capacitor charge is refreshed , so the memory cells must be periodically refreshed (rewritten). The...reliability issues (such as poor data retention problem and refresh failure). In order to avoid those problems, a 3-dimensional channel structure...states during the refresh cycle (retention time). When the channel length is scaled down, it is difficult to guarantee sufficient retention time

  11. The Eastern Dimension of America’s New European Allies

    DTIC Science & Technology

    2007-10-01

    especially the realistic prospect of eventual EU membership, the ENP is in danger of lacking sufficient momentum and incentive to promote structural ...conducted by the European Commission. This would help structure and intensify the harmonization process between candidate states and the EU.10 The... structural reforms. According to the conclusions of the Vilnius Conference in May 2006, entitled "Common Vision for a Common Neighborhood," an initiative

  12. Disposal and Reuse of Wurtsmith Air Force Base, Michigan. Environmental Impact Statement

    DTIC Science & Technology

    1989-09-01

    impacts of the Proposed Action and reasonable alternatives over the 20-year study period are summarized in Table S-2. Mitigations and Pollution ...and wastewater services for reuse. The Oscoda sewage treatment plant would eventually have to be upgraded. There is sufficient capacity in local utility...Occupational Safety and Health Administration (OSHA) regulations and National Emissions Standards for Hazardous Air Pollutants (NESHAP). A survey

  13. Self-pinched lithium beam transport experiments on SABRE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanson, D.L.; Olson, C.L.; Poukey, J.W.

    Self-pinched transport of ion beams has many advantages for ion-driven ICF applications involving high yield and energy production. The authors are currently preparing for a self-pinched lithium beam transport experiment on the SABRE accelerator. There are three transport elements that must eventually be demonstrated: (1) efficient lithium beam generation and ballistic transport to a focus at the self-pinched transport channel entrance; (2) self-pinched transport in the channel, requiring optimized injection conditions and gas breakdown; and (3) self-pinched transport of the equilibrated beam from the channel into free space, with associated aiming and stability considerations. In the present experiment, a hollowmore » annular lithium beam from an applied-B extraction ion diode will be focused to small radius (r {le} 2 cm) in a 60 cm long ballistic focus section containing argon gas at a pressure of a few Torr. The self-pinched transport channel will contain a low pressure background gas of 10--40 mTorr argon to allow sufficient net current to confine the beam for long distance transport. IPROP simulations are in progress to optimize the design of the ballistic and self-pinched transport sections. Progress on preparation of this lithium self-pinched transport experiment, including a discussion of transport system design, important gas breakdown issues, and diagnostics, will be presented.« less

  14. Stability of planar traveling waves in a Keller-Segel equation on an infinite strip domain

    NASA Astrophysics Data System (ADS)

    Chae, Myeongju; Choi, Kyudong; Kang, Kyungkeun; Lee, Jihoon

    2018-07-01

    We consider a simplified model of tumor angiogenesis, described by a Keller-Segel equation on the two dimensional domain (x , y) ∈ R ×Sλ where Sλ is the circle of perimeter λ. It is known that the system allows planar traveling wave solutions of an invading type. In case that λ is sufficiently small, we establish the nonlinear stability of traveling wave solutions in the absence of chemical diffusion if the initial perturbation is sufficiently small in some weighted Sobolev space. When chemical diffusion is present, it can be shown that the system is linearly stable. Lastly, we prove that any solution with our front condition eventually becomes planar under certain regularity conditions.

  15. Optoelectronic Devices Based on Novel Semiconductor Structures

    DTIC Science & Technology

    2006-06-14

    superlattices 4. TEM study and band -filling effects in quantum-well dots 5. Improvements on tuning ranges and output powers for widely-tunable THz sources...the pump power increases the relative strength for the QW emission in the QWD sample also increases. Eventually at the sufficiently- high pump power ...Ahopelto, Appl. Phys. Lett. 66, 2364 (1995). 5. A monochromatic and high - power THz source tunable in the ranges of 2.7-38.4 ptm and 58.2-3540 ptm for

  16. Method of depositing a high-emissivity layer

    DOEpatents

    Wickersham, Charles E.; Foster, Ellis L.

    1983-01-01

    A method of depositing a high-emissivity layer on a substrate comprising RF sputter deposition of a carbide-containing target in an atmosphere of a hydrocarbon gas and a noble gas. As the carbide is deposited on the substrate the hydrocarbon gas decomposes to hydrogen and carbon. The carbon deposits on the target and substrate causing a carbide/carbon composition gradient to form on the substrate. At a sufficiently high partial pressure of hydrocarbon gas, a film of high-emissivity pure carbon will eventually form over the substrate.

  17. Experimental Design for the Evaluation of Detection Techniques of Hidden Corrosion Beneath the Thermal Protective System of the Space Shuttle Orbiter

    NASA Technical Reports Server (NTRS)

    Kammerer, Catherine C.; Jacoby, Joseph A.; Lomness, Janice K.; Hintze, Paul E.; Russell, Richard W.

    2007-01-01

    The United States Space Operational Space Shuttle Fleet Consists of three shuttles with an average age of 19.7 years. Shuttles are exposed to corrosive conditions while undergoing final closeout for missions at the launch pad and extreme conditions during ascent, orbit, and descent that may accelerate the corrosion process. Structural corrosion under TPS could progress undetected (without tile removal) and eventually result in reduction in structural capability sufficient to create negative margins of . safety and ultimate loss of local structural capability.

  18. Consideration of Dynamical Balances

    NASA Technical Reports Server (NTRS)

    Errico, Ronald M.

    2015-01-01

    The quasi-balance of extra-tropical tropospheric dynamics is a fundamental aspect of nature. If an atmospheric analysis does not reflect such balance sufficiently well, the subsequent forecast will exhibit unrealistic behavior associated with spurious fast-propagating gravity waves. Even if these eventually damp, they can create poor background fields for a subsequent analysis or interact with moist physics to create spurious precipitation. The nature of this problem will be described along with the reasons for atmospheric balance and techniques for mitigating imbalances. Attention will be focused on fundamental issues rather than on recipes for various techniques.

  19. Risk of fractures with selective serotonin-reuptake inhibitors or tricyclic antidepressants.

    PubMed

    Ginzburg, Regina; Rosero, Enma

    2009-01-01

    To evaluate the literature associating the risk of fracture during antidepressant therapy. Literature was identified via MEDLINE (1970-August 2008) using the search terms selective serotonin-reuptake inhibitors, tricyclic antidepressants, antidepressants, and fracture. Reference citations from publications identified were also reviewed. All articles in English identified from the data sources were evaluated. Selective serotonin-reuptake inhibitors (SSRIs) are generally prescribed over other classes of antidepressants because they are considered to be relatively safer. Recent evidence, however, suggests that SSRIs may be associated with an increased risk of fractures. Thirteen clinical studies were identified in the literature search (7 case controls, 5 prospective cohorts, 1 cross-sectional). Most studies compared SSRIs with tricyclic antidepressants (TCAs) and found similar or greater risk of fracture associated with use of an SSRI. This risk appeared to be highest at the beginning of therapy with TCAs and eventually diminished. SSRI risk tended to increase slightly over time. No risk was seen with other classes of antidepressants. However, the number of patients using antidepressants was low. There may be a possible correlation with SSRI or TCA use and risk of fracture. Prospective, randomized controlled trials with sufficient patient samples are needed to verify this finding.

  20. Electrokinetic Strength Enhancement of Concrete

    NASA Technical Reports Server (NTRS)

    Cardenas, Henry E. (Inventor)

    2016-01-01

    A method and apparatus for strengthening cementitious concrete by placing a nanoparticle carrier liquid in contact with a first surface of a concrete section and inducing a current across the concrete section at sufficient magnitude and for sufficient time that nanoparticles in the nanoparticle carrier liquid migrate through a significant depth of the concrete section.

  1. Electrokenitic Corrosion Treatment of Concrete

    NASA Technical Reports Server (NTRS)

    Cardenas, Henry E (Inventor)

    2015-01-01

    A method and apparatus for strengthening cementitious concrete by placing a nanoparticle carrier liquid in contact with a first surface of a concrete section and inducing a current across the concrete section at sufficient magnitude and for sufficient time that nanoparticles in the nanoparticle carrier liquid migrate through a significant depth of the concrete section.

  2. Stem cell therapy for cardiovascular disease: the demise of alchemy and rise of pharmacology

    PubMed Central

    Jadczyk, T; Faulkner, A; Madeddu, P

    2013-01-01

    Regenerative medicine holds great promise as a way of addressing the limitations of current treatments of ischaemic disease. In preclinical models, transplantation of different types of stem cells or progenitor cells results in improved recovery from ischaemia. Furthermore, experimental studies indicate that cell therapy influences a spectrum of processes, including neovascularization and cardiomyogenesis as well as inflammation, apoptosis and interstitial fibrosis. Thus, distinct strategies might be required for specific regenerative needs. Nonetheless, clinical studies have so far investigated a relatively small number of options, focusing mainly on the use of bone marrow-derived cells. Rapid clinical translation resulted in a number of small clinical trials that do not have sufficient power to address the therapeutic potential of the new approach. Moreover, full exploitation has been hindered so far by the absence of a solid theoretical framework and inadequate development plans. This article reviews the current knowledge on cell therapy and proposes a model theory for interpretation of experimental and clinical outcomes from a pharmacological perspective. Eventually, with an increased association between cell therapy and traditional pharmacotherapy, we will soon need to adopt a unified theory for understanding how the two practices additively interact for a patient's benefit. LINKED ARTICLES This article is part of a themed section on Regenerative Medicine and Pharmacology: A Look to the Future. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2013.169.issue-2 PMID:22712727

  3. Massive juvenile nasopharyngeal angiofibroma: ode to the open surgical approach.

    PubMed

    Meher, Ravi; Arora, Nikhil; Bhargava, Eishaan Kamta; Juneja, Ruchika

    2017-08-01

    The management of juvenile nasopharyngeal angiofibroma has undergone a significant evolution, with more surgeons moving towards the minimal invasive endoscopic approaches. Although considered the standard of care by most, an endoscopic approach may not be sufficient for extensive tumours, as exemplified by the current case of a young man presenting with the largest juvenile nasopharyngeal angiofibroma described in English literature until the present that was eventually excised via an anterior external approach. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. A class of stochastic delayed SIR epidemic models with generalized nonlinear incidence rate and temporary immunity

    NASA Astrophysics Data System (ADS)

    Fan, Kuangang; Zhang, Yan; Gao, Shujing; Wei, Xiang

    2017-09-01

    A class of SIR epidemic model with generalized nonlinear incidence rate is presented in this paper. Temporary immunity and stochastic perturbation are also considered. The existence and uniqueness of the global positive solution is achieved. Sufficient conditions guaranteeing the extinction and persistence of the epidemic disease are established. Moreover, the threshold behavior is discussed, and the threshold value R0 is obtained. We show that if R0 < 1, the disease eventually becomes extinct with probability one, whereas if R0 > 1, then the system remains permanent in the mean.

  5. Authorship issues in multi-centre clinical trials: the importance of making an authorship contract.

    PubMed

    Rosenberg, Jacob; Burcharth, Jakob; Pommergaard, Hans-Christian; Vinther, Siri

    2015-02-01

    Discussions about authorship often arise in multi-centre clinical trials. Such trials may involve up to hundreds of contributors of whom some will eventually co-author the final publication. It is, however, often impossible to involve all contributors in the manuscript process sufficiently for them to qualify for authorship as defined by the International Committee of Medical Journal Editors. Therefore, rules for authorship in multi-centre trials are strongly recommended. We propose two contracts to prevent conflicts regarding authorship; both are freely available for use without pay but with reference to the original source.

  6. Fatigue failure processes in aligned carbon-epoxy laminates

    NASA Astrophysics Data System (ADS)

    Piggott, Michael R.; Lam, Patrick W. K.

    The failure mechanism involved in the tensile-tensile fatigue of carbon fiber-reinforced polymer matrices may be initiated by the fiber curvature that can be present in the composite. The varying stresses encountered in fatigue begin to damage the composite at the antinodes of the fiber profiles, perhaps in the form of fiber debonds that generate matrix cracks and result in comminution of the polymer; eventually, as the process proceeds, the flexural stresses in the fiber are sufficiently great to cause early fiber failure in wavy regions. The breaks are connected by splits in the polymer.

  7. Advanced Computation Dynamics Simulation of Protective Structures Research

    DTIC Science & Technology

    2013-02-01

    additional load with increased cracking and deflection. Eventually, the walls failed in flexure due to self-weight and did not indicate any signs of shear...overall volume of the FEM block to be 432.2 in3, instead of 415.1 in3; the overall volume increased of area is 1.041%. This additional material is...sections in addition to the summary. Section 2 consists of an introduction, objectives, scope and methodology, and organization of the report. Section 2

  8. Lateral Erosion Encourages Vertical Incision in a Bimodal Alluvial River

    NASA Astrophysics Data System (ADS)

    Gran, K. B.

    2015-12-01

    Sand can have a strong impact on gravel transport, increasing gravel transport rates by orders of magnitude as sand content increases. Recent experimental work by others indicates that adding sand to an armored bed can even cause armor to break-up and mobilize. These two elements together help explain observations from a bimodal sand and gravel-bedded river, where lateral migration into sand-rich alluvium breaks up the armor layer, encouraging further incision into the bed. Detailed bedload measurements were coupled with surface and subsurface grain size analyses and cross-sectional surveys in a seasonally-incised channel carved into the upper alluvial fan of the Pasig-Potrero River at Mount Pinatubo, Philippines. Pinatubo erupted in 1991, filling valleys draining the flanks of the volcano with primarily sand-sized pyroclastic flow debris. Twenty years after the eruption, sand-rich sediment inputs are strongly seasonal, with most sediment input to the channel during the rainy season. During the dry season, flow condenses from a wide braided planform to a single-thread channel in most of the upper basin, extending several km onto the alluvial fan. This change in planform creates similar unit discharge ranges in summer and winter. Lower sediment loads in the dry season drive vertical incision until the bed is sufficiently armored. Incision proceeds downstream in a wave, with increasing sediment transport rates and decreasing grain size with distance downstream, eventually reaching a gravel-sand transition and return to a braided planform. Incision depths in the gravel-bedded section exceeded 3 meters in parts of a 4 km-long study reach, a depth too great to be explained by predictions from simple winnowing during incision. Instead, lateral migration into sand-rich alluvium provides sufficient fine sediment to break up the armor surface, allowing incision to start anew and increasing the total depth of the seasonally-incised valley. Lateral migration is recorded in a series of inset terraces within the valley. The importance of sand on channel behavior thus extends beyond transport rates, affecting the depth of incision and volume of material excavated during a rainy to dry season transition.

  9. Thermal electric vapor trap arrangement and method

    DOEpatents

    Alger, Terry

    1988-01-01

    A technique for trapping vapor within a section of a tube is disclosed herein. This technique utilizes a conventional, readily providable thermal electric device having a hot side and a cold side and means for powering the device to accomplish this. The cold side of this device is positioned sufficiently close to a predetermined section of the tube and is made sufficiently cold so that any condensable vapor passing through the predetermined tube section is condensed and trapped, preferably within the predetermined tube section itself.

  10. Thermal electric vapor trap arrangement and method

    DOEpatents

    Alger, T.

    1988-03-15

    A technique for trapping vapor within a section of a tube is disclosed herein. This technique utilizes a conventional, readily providable thermal electric device having a hot side and a cold side and means for powering the device to accomplish this. The cold side of this device is positioned sufficiently close to a predetermined section of the tube and is made sufficiently cold so that any condensable vapor passing through the predetermined tube section is condensed and trapped, preferably within the predetermined tube section itself. 4 figs.

  11. 17 CFR 36.2 - Exempt boards of trade.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... supply that is sufficiently large, and a cash market sufficiently liquid, to render any contract traded... market. (2) The commodities that meet the criteria of paragraph (a)(1) of this section are: (i) The...

  12. 17 CFR 36.2 - Exempt boards of trade.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... supply that is sufficiently large, and a cash market sufficiently liquid, to render any contract traded... market. (2) The commodities that meet the criteria of paragraph (a)(1) of this section are: (i) The...

  13. Bubble propagation in Hele-Shaw channels with centred constrictions

    NASA Astrophysics Data System (ADS)

    Franco-Gómez, Andrés; Thompson, Alice B.; Hazel, Andrew L.; Juel, Anne

    2018-04-01

    We study the propagation of finite bubbles in a Hele-Shaw channel, where a centred occlusion (termed a rail) is introduced to provide a small axially uniform depth constriction. For bubbles wide enough to span the channel, the system’s behaviour is similar to that of semi-infinite fingers and a symmetric static solution is stable. Here, we focus on smaller bubbles, in which case the symmetric static solution is unstable and the static bubble is displaced towards one of the deeper regions of the channel on either side of the rail. Using a combination of experiments and numerical simulations of a depth-averaged model, we show that a bubble propagating axially due to a small imposed flow rate can be stabilised in a steady symmetric mode centred on the rail through a subtle interaction between stabilising viscous forces and destabilising surface tension forces. However, for sufficiently large capillary numbers Ca, the ratio of viscous to surface tension forces, viscous forces in turn become destabilising thus returning the bubble to an off-centred propagation regime. With decreasing bubble size, the range of Ca for which steady centred propagation is stable decreases, and eventually vanishes through the coalescence of two supercritical pitchfork bifurcations. The depth-averaged model is found to accurately predict all the steady modes of propagation observed experimentally, and provides a comprehensive picture of the underlying steady bifurcation structure. However, for sufficiently large imposed flow rates, we find that initially centred bubbles do not converge onto a steady mode of propagation. Instead they transiently explore weakly unstable steady modes, an evolution which results in their break-up and eventual settling into a steady propagating state of changed topology.

  14. Helping Low-Income Mothers with Criminal Records Achieve Self-Sufficiency.

    ERIC Educational Resources Information Center

    Brown, Rebecca

    2000-01-01

    This issue of WIN (Welfare Information Network) Issue Notes focuses on helping low-income mothers with criminal records achieve self-sufficiency. Section 1 offers background. Section 2 answers these policy questions: why states might want to focus on serving low-income mothers with criminal records; how states can encourage employers to hire…

  15. Synthesis of Intrinsically Disordered Fluorinated Peptides for Modular Design of High-Signal 19 F MRI Agents.

    PubMed

    Kirberger, Steven E; Maltseva, Sofia D; Manulik, Joseph C; Einstein, Samuel A; Weegman, Bradley P; Garwood, Michael; Pomerantz, William C K

    2017-06-01

    19 F MRI is valuable for in vivo imaging due to the only trace amounts of fluorine in biological systems. Because of the low sensitivity of MRI however, designing new fluorochemicals remains a significant challenge for achieving sufficient 19 F signal. Here, we describe a new class of high-signal, water-soluble fluorochemicals as 19 F MRI imaging agents. A polyamide backbone is used for tuning the proteolytic stability to avoid retention within the body, which is a limitation of current state-of-the-art perfluorochemicals. We show that unstructured peptides containing alternating N-ϵ-trifluoroacetyllysine and lysine provide a degenerate 19 F NMR signal. 19 F MRI phantom images provide sufficient contrast at micromolar concentrations, showing promise for eventual clinical applications. Finally, the degenerate high signal characteristics were retained when conjugated to a large protein, indicating potential for in vivo targeting applications, including molecular imaging and cell tracking. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. In situ X-ray micro-CT characterization of chemo-mechanical relaxations during Sn lithiation

    NASA Astrophysics Data System (ADS)

    Gonzalez, Joseph F.; Antartis, Dimitrios A.; Chasiotis, Ioannis; Dillon, Shen J.; Lambros, John

    2018-03-01

    Sn has been proposed for use as a high capacity anode material. Because of its ductile metallic nature, Sn may exhibit unique stress evolution during lithiation. Here, 2D radiography and 3D tomography are employed to visualize the evolution of geometry, internal structure, alloying, and damage during lithiation, delithiation, and rest of Sn wires with micron scale diameters. Lithiation proceeds isotropically, resulting in geometric and dimensional changes after 25% of total lithiation when the tensile stresses are sufficiently high to exceed the flow stress of the unlithiated Sn core and cause elongation and diameter increase. Damage occurs at later stages in the form of cracks terminating at the wire surface and voids forming in the unlithiated core. Notably, significant fragmentation occurs during delithiation which, due to void formation that accommodates the resulting stresses, does not measurably alter the wire cross-section and length. The distinguishing feature of the chemo-mechanics of Sn compared to Si or Ge is the pronounced creep rate at applied strain rates as high as 10-6 s-1, which promotes large strains in the core, eventually leading to void nucleation in the unlithiated core during lithiation, and more importantly, continues driving the deformation of the anode while at rest.

  17. The interaction of radio frequency electromagnetic fields with atmospheric water droplets and applications to aircraft ice prevention. Thesis

    NASA Technical Reports Server (NTRS)

    Hansman, R. J., Jr.

    1982-01-01

    The feasibility of computerized simulation of the physics of advanced microwave anti-icing systems, which preheat impinging supercooled water droplets prior to impact, was investigated. Theoretical and experimental work performed to create a physically realistic simulation is described. The behavior of the absorption cross section for melting ice particles was measured by a resonant cavity technique and found to agree with theoretical predictions. Values of the dielectric parameters of supercooled water were measured by a similar technique at lambda = 2.82 cm down to -17 C. The hydrodynamic behavior of accelerated water droplets was studied photograhically in a wind tunnel. Droplets were found to initially deform as oblate spheroids and to eventually become unstable and break up in Bessel function modes for large values of acceleration or droplet size. This confirms the theory as to the maximum stable droplet size in the atmosphere. A computer code which predicts droplet trajectories in an arbitrary flow field was written and confirmed experimentally. The results were consolidated into a simulation to study the heating by electromagnetic fields of droplets impinging onto an object such as an airfoil. It was determined that there is sufficient time to heat droplets prior to impact for typical parameter values. Design curves for such a system are presented.

  18. 3D flow focusing for microfluidic flow cytometry with ultrasonics

    NASA Astrophysics Data System (ADS)

    Gnyawali, Vaskar; Strohm, Eric M.; Daghighi, Yasaman; van de Vondervoort, Mia; Kolios, Michael C.; Tsai, Scott S. H.

    2015-11-01

    We are developing a flow cytometer that detects unique acoustic signature waves generated from single cells due to interactions between the cells and ultrasound waves. The generated acoustic waves depend on the size and biomechanical properties of the cells and are sufficient for identifying cells in the medium. A microfluidic system capable of focusing cells through a 10 x 10 μm ultrasound beam cross section was developed to facilitate acoustic measurements of single cells. The cells are streamlined in a hydro-dynamically 3D focused flow in a 300 x 300 μm channel made using PDMS. 3D focusing is realized by lateral sheath flows and an inlet needle (inner diameter 100 μm). The accuracy of the 3D flow focusing is measured using a dye and detecting its localization using confocal microscopy. Each flowing cell would be probed by an ultrasound pulse, which has a center frequency of 375 MHz and bandwidth of 250 MHz. The same probe would also be used for recording the scattered waves from the cells, which would be processed to distinguish the physical and biomechanical characteristics of the cells, eventually identifying them. This technique has potential applications in detecting circulating tumor cells, blood cells and blood-related diseases.

  19. Dimethoate and atrazine retention from aqueous solution by nanofiltration membranes.

    PubMed

    Ahmad, A L; Tan, L S; Shukor, S R Abd

    2008-02-28

    In order to produce sufficient food supply for the ever-increasing human population, pesticides usage is indispensable in the agriculture sector to control crop losses. However, the effect of pesticides on the environment is very complex as undesirable transfers occur continually among different environmental sections. This eventually leads to contamination of drinking water source especially for rivers located near active agriculture practices. This paper studied the application of nanofiltration membrane in the removal of dimethoate and atrazine in aqueous solution. Dimethoate was selected as the subject of study since it is being listed as one of the pesticides in guidelines for drinking water by World Health Organization. Nevertheless, data on effectiveness of dimethoate rejection using membranes has not been found so far. Meanwhile, atrazine is classified as one of the most commonly used pesticides in Malaysia. Separation was done using a small batch-type membrane separation cell with integrated magnetic stirrer while concentration of dimethoate and atrazine in aqueous solution was analyzed using high performance liquid chromatography (HPLC). Four nanofiltration membranes NF90, NF200, NF270 and DK were tested for their respective performance to separate dimethoate and atrazine. Of all four membranes, NF90 showed the best performance in retention of dimethoate and atrazine in water.

  20. Influence of cross section variations on the structural behaviour of composite rotor blades

    NASA Astrophysics Data System (ADS)

    Rapp, Helmut; Woerndle, Rudolf

    1991-09-01

    A highly sophisticated structural analysis is required for helicopter rotor blades with nonhomogeneous cross sections made from nonisotropic material. Combinations of suitable analytical techniques with FEM-based techniques permit a cost effective and sufficiently accurate analysis of these complicated structures. It is determined that in general the 1D engineering theory of bending combined with 2D theories for determining the cross section properties is sufficient to describe the structural blade behavior.

  1. 20 CFR 633.102 - Scope and purpose of title IV, section 402 programs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... substantially aggravated by continual advancements in technology and mechanization resulting in displacement and... eventual placement in unsubsidized agricultural or nonagricultural employment; (3) Allow activities leading to stabilization in agricultural employment; and (4) Include related assistance and supportive...

  2. Science Directorate Publications and Presentations, January 1 - December 31, 2002

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2003-01-01

    This Technical Memorandum lists the significant publications and presentations of the Science Directorate during the period January 1-December 31, 2002. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

  3. Mechanics of Boundary Layer Transition. Part 5: Boundary Layer Stability theory in incompressible and compressible flow

    NASA Technical Reports Server (NTRS)

    Mack, L. M.

    1967-01-01

    The fundamentals of stability theory, its chief results, and the physical mechanisms at work are presented. The stability theory of the laminar boundary determines whether a small disturbance introduced into the boundary layer will amplify or damp. If the disturbance damps, the boundary layer remains laminar. If the disturbance amplifies, and by a sufficient amount, then transition to turbulence eventually takes place. The stability theory establishes those states of the boundary layer which are most likely to lead to transition, identifys those frequencies which are the most dangerous, and indicates how the external parameters can best be changed to avoid transition.

  4. Productivity loss of caregivers of schizophrenia patients: a cross-sectional survey in Japan.

    PubMed

    Sruamsiri, Rosarin; Mori, Yasuhiro; Mahlich, Jörg

    2018-04-27

    When a family member is diagnosed with schizophrenia, it causes stress to the caregiver that can eventually result in missed work days and lower work performance. This study aims at revealing productivity costs for caregivers of schizophrenia patients in Japan. A cross-sectional survey of caregivers was conducted and resulted in 171 respondents. The assessment of work productivity included calculating the costs of absenteeism, presenteeism and total productivity costs. This was accomplished using the "Work Productivity and Activity Impairment Questionnaire" (WPAI). A relative majority of caregivers in the sample provided care for their spouse (47%), 18% cared for their brother or sister and 16% provided care for their child. Per capita productivity costs totaled JPY 2.42 million, with JPY 2.36 million (97%) of that amount being due to presenteeism. The burden on caregivers is substantial enough to warrant structured support programs aimed at maintaining careers' physical and mental health, helping them provide more effective care to schizophrenia patients and eventually increase productivity at work.

  5. 33 CFR 115.30 - Sufficiency of State authority for bridges.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... for bridges. 115.30 Section 115.30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.30 Sufficiency of State authority for bridges. An opinion of the attorney general of the State as to the sufficiency of State...

  6. 33 CFR 115.30 - Sufficiency of State authority for bridges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for bridges. 115.30 Section 115.30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES BRIDGE LOCATIONS AND CLEARANCES; ADMINISTRATIVE PROCEDURES § 115.30 Sufficiency of State authority for bridges. An opinion of the attorney general of the State as to the sufficiency of State...

  7. 39 CFR 491.3 - Sufficient legal form.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Sufficient legal form. 491.3 Section 491.3 Postal... AND THE POSTAL RATE COMMISSION § 491.3 Sufficient legal form. No document purporting to garnish... is legal process in the nature of garnishment; that it is issued by a court of competent jurisdiction...

  8. 39 CFR 491.3 - Sufficient legal form.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Sufficient legal form. 491.3 Section 491.3 Postal... AND THE POSTAL RATE COMMISSION § 491.3 Sufficient legal form. No document purporting to garnish... is legal process in the nature of garnishment; that it is issued by a court of competent jurisdiction...

  9. 27 CFR 25.174 - Bond not sufficient.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bond not sufficient. 25.174 Section 25.174 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Prepayment of Tax § 25.174 Bond not sufficient. When the...

  10. 27 CFR 25.174 - Bond not sufficient.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Bond not sufficient. 25.174 Section 25.174 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Prepayment of Tax § 25.174 Bond not sufficient. When the...

  11. 27 CFR 25.174 - Bond not sufficient.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Bond not sufficient. 25.174 Section 25.174 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Prepayment of Tax § 25.174 Bond not sufficient. When the...

  12. 27 CFR 25.174 - Bond not sufficient.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Bond not sufficient. 25.174 Section 25.174 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Prepayment of Tax § 25.174 Bond not sufficient. When the...

  13. 27 CFR 25.174 - Bond not sufficient.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Bond not sufficient. 25.174 Section 25.174 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Prepayment of Tax § 25.174 Bond not sufficient. When the...

  14. Blockage Testing in the NASA Glenn 225 Square Centimeter Supersonic Wind Tunnel

    NASA Technical Reports Server (NTRS)

    Sevier, Abigail; Davis, David O.; Schoenenberger, Mark

    2017-01-01

    The starting characteristics for three different model geometries were tested in the Glenn Research Center 225 Square Centimeter Supersonic Wind Tunnel. The test models were tested at Mach 2, 2.5 and 3 in a square test section and at Mach 2.5 again in an asymmetric test section. The results gathered in this study will help size the test models and inform other design features for the eventual implementation of a magnetic suspension system.

  15. 49 CFR 40.193 - What happens when an employee does not provide a sufficient amount of urine for a drug test?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... sufficient amount of urine for a drug test? 40.193 Section 40.193 Transportation Office of the Secretary of... § 40.193 What happens when an employee does not provide a sufficient amount of urine for a drug test... sufficient amount of urine to permit a drug test (i.e., 45 mL of urine). (b) As the collector, you must do...

  16. 49 CFR 40.193 - What happens when an employee does not provide a sufficient amount of urine for a drug test?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... sufficient amount of urine for a drug test? 40.193 Section 40.193 Transportation Office of the Secretary of... § 40.193 What happens when an employee does not provide a sufficient amount of urine for a drug test... sufficient amount of urine to permit a drug test (i.e., 45 mL of urine). (b) As the collector, you must do...

  17. 49 CFR 40.193 - What happens when an employee does not provide a sufficient amount of urine for a drug test?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... sufficient amount of urine for a drug test? 40.193 Section 40.193 Transportation Office of the Secretary of... § 40.193 What happens when an employee does not provide a sufficient amount of urine for a drug test... sufficient amount of urine to permit a drug test (i.e., 45 mL of urine). (b) As the collector, you must do...

  18. 49 CFR 40.193 - What happens when an employee does not provide a sufficient amount of urine for a drug test?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... sufficient amount of urine for a drug test? 40.193 Section 40.193 Transportation Office of the Secretary of... § 40.193 What happens when an employee does not provide a sufficient amount of urine for a drug test... sufficient amount of urine to permit a drug test (i.e., 45 mL of urine). (b) As the collector, you must do...

  19. Breakdown of the conservative potential equation

    NASA Technical Reports Server (NTRS)

    Salas, M. D.; Gumbert, C. R.

    1986-01-01

    The conservative full-potential equation is used to study transonic flow over five airfoil sections. The results of the study indicate that once shock are present in the flow, the qualitative approximation is different from that observed with the Euler equations. The difference in behavior of the potential eventually leads to multiple solutions.

  20. Building Maintenance Syllabus.

    ERIC Educational Resources Information Center

    Fischer, Joseph; Messier, Joseph

    Building maintenance is a basic two-year trade education course requiring 2 1/2 hours of study on each of 160 teaching days per year. Student abilities should range from those capable of the simplest custodial work to those who may eventually be superintendents of building complexes. The syllabus is organized in sections by traditional skills…

  1. 78 FR 16713 - Board Meeting; April 16, 2013; Richland, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... in a repository. Pursuant to its authority under section 5051 of Public Law 100-203, Nuclear Waste... facility in preparation for eventual disposal in a deep geologic repository. State, local, and regional... DOE's work related to the potential direct disposal in a deep geologic repository of existing SNF...

  2. The Last Book: The Delivery of Future Content.

    ERIC Educational Resources Information Center

    Lim, Edward

    This paper discusses the future of the printed book. The first section considers factors contributing to predictions of its eventual demise and replacement by electronic versions, the increasing volume of digitized material, superior characteristics of digital publications, and the development of technologies that will allow the e-book to become…

  3. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to...

  4. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to...

  5. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to...

  6. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to...

  7. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Problems in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to...

  8. Chapter 8: Materials for Exploration Systems

    NASA Technical Reports Server (NTRS)

    Curreri, Peter A.

    2017-01-01

    Materials science and processing research in space can be thought of as a field of study that began with the sounding rocket experiments in the 1950s. Material science studies of the lunar surface materials returned during the Apollo missions enabled the study of lunar resource utilization. The study of materials science and processing in space continued with over 30 years of microgravity materials processing research which continues today in the International Space Station. These studies are the technical foundation that could enable lower cost human exploration through the use of in-situ propellant production, the production of energy from space resources, and the eventual establishment of a substantial portion of humanity living self sufficiently off Earth.

  9. Science and Exploration Research Office Publications and Presentations, January 1-December 31, 2006

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2007-01-01

    This Technical Memorandum (TM) lists the significant publications and presentations of the Science and Exploration Research Office during the period January 1-December 31, 2006. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

  10. Design Approaches to Myocardial and Vascular Tissue Engineering.

    PubMed

    Akintewe, Olukemi O; Roberts, Erin G; Rim, Nae-Gyune; Ferguson, Michael A H; Wong, Joyce Y

    2017-06-21

    Engineered tissues represent an increasingly promising therapeutic approach for correcting structural defects and promoting tissue regeneration in cardiovascular diseases. One of the challenges associated with this approach has been the necessity for the replacement tissue to promote sufficient vascularization to maintain functionality after implantation. This review highlights a number of promising prevascularization design approaches for introducing vasculature into engineered tissues. Although we focus on encouraging blood vessel formation within myocardial implants, we also discuss techniques developed for other tissues that could eventually become relevant to engineered cardiac tissues. Because the ultimate solution to engineered tissue vascularization will require collaboration between wide-ranging disciplines such as developmental biology, tissue engineering, and computational modeling, we explore contributions from each field.

  11. Sufficient Forecasting Using Factor Models

    PubMed Central

    Fan, Jianqing; Xue, Lingzhou; Yao, Jiawei

    2017-01-01

    We consider forecasting a single time series when there is a large number of predictors and a possible nonlinear effect. The dimensionality was first reduced via a high-dimensional (approximate) factor model implemented by the principal component analysis. Using the extracted factors, we develop a novel forecasting method called the sufficient forecasting, which provides a set of sufficient predictive indices, inferred from high-dimensional predictors, to deliver additional predictive power. The projected principal component analysis will be employed to enhance the accuracy of inferred factors when a semi-parametric (approximate) factor model is assumed. Our method is also applicable to cross-sectional sufficient regression using extracted factors. The connection between the sufficient forecasting and the deep learning architecture is explicitly stated. The sufficient forecasting correctly estimates projection indices of the underlying factors even in the presence of a nonparametric forecasting function. The proposed method extends the sufficient dimension reduction to high-dimensional regimes by condensing the cross-sectional information through factor models. We derive asymptotic properties for the estimate of the central subspace spanned by these projection directions as well as the estimates of the sufficient predictive indices. We further show that the natural method of running multiple regression of target on estimated factors yields a linear estimate that actually falls into this central subspace. Our method and theory allow the number of predictors to be larger than the number of observations. We finally demonstrate that the sufficient forecasting improves upon the linear forecasting in both simulation studies and an empirical study of forecasting macroeconomic variables. PMID:29731537

  12. Who’s in Charge: The Federal/State Conflict for Control of the National Guard.

    DTIC Science & Technology

    1988-03-30

    35 BIBLIOGRAPHY .............................................. 37 ’ -’ AiiCeio For L. I, NT~, r N WHC)’S TN CH2ARGE The...eventually attempt to examine the merger bugaboo .... that we would then be fighting literally for the continued existence 7f the National Guard’s...469. 31. In 1956 these sections were codified into positive law as sections 672(b) and 672( d ) of Title 10 U.S.C., Act of August 10, 1956, ch 1041, 70A

  13. Comparison of Outcomes of antibiotic Drugs and Appendectomy (CODA) trial: a protocol for the pragmatic randomised study of appendicitis treatment

    PubMed Central

    Davidson, Giana H; Flum, David R; Talan, David A; Kessler, Larry G; Lavallee, Danielle C; Bizzell, Bonnie J; Farjah, Farhood; Stewart, Skye D; Krishnadasan, Anusha; Carney, Erin E; Wolff, Erika M; Comstock, Bryan A; Monsell, Sarah E; Heagerty, Patrick J; Ehlers, Annie P; DeUgarte, Daniel A; Kaji, Amy H; Evans, Heather L; Yu, Julianna T; Mandell, Katherine A; Doten, Ian C; Clive, Kevin S; McGrane, Karen M; Tudor, Brandon C; Foster, Careen S; Saltzman, Darin J; Thirlby, Richard C; Lange, Erin O; Sabbatini, Amber K; Moran, Gregory J

    2017-01-01

    Introduction Several European studies suggest that some patients with appendicitis can be treated safely with antibiotics. A portion of patients eventually undergo appendectomy within a year, with 10%–15% failing to respond in the initial period and a similar additional proportion with suspected recurrent episodes requiring appendectomy. Nearly all patients with appendicitis in the USA are still treated with surgery. A rigorous comparative effectiveness trial in the USA that is sufficiently large and pragmatic to incorporate usual variations in care and measures the patient experience is needed to determine whether antibiotics are as good as appendectomy. Objectives The Comparing Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial for acute appendicitis aims to determine whether the antibiotic treatment strategy is non-inferior to appendectomy. Methods/Analysis CODA is a randomised, pragmatic non-inferiority trial that aims to recruit 1552 English-speaking and Spanish-speaking adults with imaging-confirmed appendicitis. Participants are randomised to appendectomy or 10 days of antibiotics (including an option for complete outpatient therapy). A total of 500 patients who decline randomisation but consent to follow-up will be included in a parallel observational cohort. The primary analytic outcome is quality of life (measured by the EuroQol five dimension index) at 4 weeks. Clinical adverse events, rate of eventual appendectomy, decisional regret, return to work/school, work productivity and healthcare utilisation will be compared. Planned exploratory analyses will identify subpopulations that may have a differential risk of eventual appendectomy in the antibiotic treatment arm. Ethics and dissemination This trial was approved by the University of Washington’s Human Subjects Division. Results from this trial will be presented in international conferences and published in peer-reviewed journals. Trial registration number NCT02800785. PMID:29146633

  14. Modeling the Sliding/Falling Ladder Paradox

    ERIC Educational Resources Information Center

    Fox, William P.; Fox, James B.

    2003-01-01

    Recently we were presented with an interesting twist to the sliding ladder problem viewed in the related rates section of most calculus textbooks. Our problem concerning a sliding ladder that eventually hits the ground. At first, those attempting this problem fell into the calculus trap using only related rates. Previous work for this problem…

  15. The Role of Faulting on the Growth of a Carbonate Platform: Evidence from 3D Seismic Analysis and Section Restoration

    NASA Astrophysics Data System (ADS)

    Nur Fathiyah Jamaludin, Siti; Pubellier, Manuel; Prasad Ghosh, Deva; Menier, David; Pierson, Bernard

    2014-05-01

    Tectonics in addition to other environmental factors impacts the growth of carbonate platforms and plays an important role in shaping the internal architecture of the platforms. Detailed of faults and fractures development and healing in carbonate environment have not been explored sufficiently. Using 3D seismic and well data, we attempt to reconstruct the structural evolution of a Miocene carbonate platform in Central Luconia Province, offshore Malaysia. Luconia Province is located in the NW coast of Borneo and has become one of the largest carbonate factories in SE Asia. Seismic interpretations including seismic attribute analysis are applied to the carbonate platform to discern its sedimentology and structural details. Detailed seismic interpretations highlight the relationships of carbonate deposition with syn-depositional faulting. Branching conjugate faults are common in this carbonate platform and have become a template for reef growth, attesting lateral facies changes within the carbonate environments. Structural restoration was then appropriately performed on the interpreted seismic sections based on sequential restoration techniques, and provided images different from those of horizon flattening methods. This permits us to compensate faults' displacement, remove recent sediment layers and finally restore the older rock units prior to the fault motions. It allows prediction of platform evolution as a response to faulting before and after carbonate deposition and also enhances the pitfalls of interpretation. Once updated, the reconstructions allow unravelling of the un-seen geological features underneath the carbonate platform, such as paleo-structures and paleo-topography which in turn reflects the paleo-environment before deformations took place. Interestingly, sections balancing and restoration revealed the late-phase (Late Oligocene-Early Miocene) rifting of South China Sea, otherwise difficult to visualize on seismic sections. Later it is shown that this carbonate platform was possibly originated from two or more connected reef build-ups. The platform evolution in terms of tectonic influences on carbonate growth and development may serve as a case example for re-evaluation of pre-Late Miocene structures as a new potential target for hydrocarbon exploration in Central Luconia Province. Eventually, techniques used in this study might be of interest to oil and gas explorers in carbonate system.

  16. Mechanisms, determination and the metaphysics of neuroscience.

    PubMed

    Soom, Patrice

    2012-09-01

    In this paper, I evaluate recently defended mechanistic accounts of the unity of neuroscience from a metaphysical point of view. Considering the mechanistic framework in general (Sections 2 and 3), I argue that explanations of this kind are essentially reductive (Section 4). The reductive character of mechanistic explanations provides a sufficiency criterion, according to which the mechanism underlying a certain phenomenon is sufficient for the latter. Thus, the concept of supervenience can be used in order to describe the relation between mechanisms and phenomena (Section 5). Against this background, I show that the mechanistic framework is subject to the causal exclusion problem and faces the classical metaphysical options when it comes to the relations obtaining between different levels of mechanisms (Section 6). Finally, an attempt to improve the metaphysics of mechanisms is made (Section 7) and further difficulties are pointed out (Section 8). Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Distribution of Off-Diagonal Cross Sections in Quantum Chaotic Scattering: Exact Results and Data Comparison.

    PubMed

    Kumar, Santosh; Dietz, Barbara; Guhr, Thomas; Richter, Achim

    2017-12-15

    The recently derived distributions for the scattering-matrix elements in quantum chaotic systems are not accessible in the majority of experiments, whereas the cross sections are. We analytically compute distributions for the off-diagonal cross sections in the Heidelberg approach, which is applicable to a wide range of quantum chaotic systems. Thus, eventually, we fully solve a problem that already arose more than half a century ago in compound-nucleus scattering. We compare our results with data from microwave and compound-nucleus experiments, particularly addressing the transition from isolated resonances towards the Ericson regime of strongly overlapping ones.

  18. Distribution of Off-Diagonal Cross Sections in Quantum Chaotic Scattering: Exact Results and Data Comparison

    NASA Astrophysics Data System (ADS)

    Kumar, Santosh; Dietz, Barbara; Guhr, Thomas; Richter, Achim

    2017-12-01

    The recently derived distributions for the scattering-matrix elements in quantum chaotic systems are not accessible in the majority of experiments, whereas the cross sections are. We analytically compute distributions for the off-diagonal cross sections in the Heidelberg approach, which is applicable to a wide range of quantum chaotic systems. Thus, eventually, we fully solve a problem that already arose more than half a century ago in compound-nucleus scattering. We compare our results with data from microwave and compound-nucleus experiments, particularly addressing the transition from isolated resonances towards the Ericson regime of strongly overlapping ones.

  19. Tracking Rates and History along the Transcontinental Railroad

    ERIC Educational Resources Information Center

    Perham, Arnold E.; Perham, Faustine L.

    2015-01-01

    The Transcontinental Railroad began laying track east from Sacramento, California, in 1863 and west from Omaha, Nebraska, in 1865; the two lines eventually met in Promontory Summit, Utah, in 1869. One of the train towns, Ogallala, Nebraska, consisted of only a section house and water tank alongside newly laid track. Over the next few years, train…

  20. 77 FR 74847 - Modifications to Statement of Policy for Section 19 of the Federal Deposit Insurance Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ... noted the authority of the Board of Governors of the Federal Reserve System and the Office of Thrift... entry, whether formal or informal, is characterized by a suspension or eventual dismissal of charges or... holding company jurisdiction to the Board of Governors of the Federal Reserve System. In addition, the...

  1. Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

    PubMed

    Hacke, Moritz; Björkholm, Patrik; Hellwig, Andrea; Himmels, Patricia; Ruiz de Almodóvar, Carmen; Brügger, Britta; Wieland, Felix; Ernst, Andreas M

    2015-07-09

    The high pathogenicity of the Ebola virus reflects multiple concurrent processes on infection. Among other important determinants, Ebola fusogenic glycoprotein (GP) has been associated with the detachment of infected cells and eventually leads to vascular leakage and haemorrhagic fever. Here we report that the membrane-anchored GP is sufficient to induce the detachment of adherent cells. The results show that the detachment induced through either full-length GP1,2 or the subunit GP2 depends on cholesterol and the structure of the transmembrane domain. These data reveal a novel molecular mechanism in which GP regulates Ebola virus assembly and suggest that cholesterol-reducing agents could be useful as therapeutics to counteract GP-mediated cell detachment.

  2. Progress, Prospects, and Problems in Epstein-Barr Virus Vaccine Development

    PubMed Central

    Balfour, Henry H.

    2014-01-01

    Epstein-Barr virus (EBV) is responsible for a farrago of acute and chronic human diseases including cancer. A prophylactic vaccine could reduce this disease burden. Several EBV vaccines have been given to humans but none has been sufficiently studied to establish safety and efficacy. EBV vaccine development has been hampered by the lack of an animal model other than subhuman primates, proprietary issues, selection of an appropriate adjuvant, and failure to reach consensus on what an EBV vaccine could or should actually achieve. A recent conference at the U.S. National Institutes of Health emphasizing the global importance of EBV vaccine and advocating a phase 3 trial to prevent infectious mononucleosis should encourage research that could eventually lead to its licensure. PMID:24632197

  3. Science Directorate Publications and Presentations: January 1-December 31, 2000

    NASA Astrophysics Data System (ADS)

    Summers, F. G.

    2001-07-01

    This document lists the significant publications and presentations of the Science Directorate during the period January 1 - December 31, 2000. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an Appendix (arranged by page number). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

  4. Anderson localization of partially incoherent light

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Capeta, D.; Radic, J.; Buljan, H.

    We study Anderson localization and propagation of partially spatially incoherent wavepackets in linear disordered potentials, motivated by the insight that interference phenomena resulting from multiple scattering are affected by the coherence of the waves. We find that localization is delayed by incoherence: the more incoherent the waves are, the longer they diffusively spread while propagating in the medium. However, if all the eigenmodes of the system are exponentially localized (as in one- and two-dimensional disordered systems), any partially incoherent wavepacket eventually exhibits localization with exponentially decaying tails, after sufficiently long propagation distances. Interestingly, we find that the asymptotic behavior ofmore » the incoherent beam is similar to that of a single instantaneous coherent realization of the beam.« less

  5. AX-5 space suit bearing torque investigation

    NASA Technical Reports Server (NTRS)

    Loewenthal, Stuart; Vykukal, Vic; Mackendrick, Robert; Culbertson, Philip, Jr.

    1990-01-01

    The symptoms and eventual resolution of a torque increase problem occurring with ball bearings in the joints of the AX-5 space suit are described. Starting torques that rose 5 to 10 times initial levels were observed in crew evaluation tests of the suit in a zero-g water tank. This bearing problem was identified as a blocking torque anomaly, observed previously in oscillatory gimbal bearings. A large matrix of lubricants, ball separator designs and materials were evaluated. None of these combinations showed sufficient tolerance to lubricant washout when repeatedly cycled in water. The problem was resolved by retrofitting a pressure compensated, water exclusion seal to the outboard side of the bearing cavity. The symptoms and possible remedies to blocking are discussed.

  6. Science Directorate Publications and Presentations: January 1-December 31, 2000

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2001-01-01

    This document lists the significant publications and presentations of the Science Directorate during the period January 1 - December 31, 2000. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an Appendix (arranged by page number). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

  7. 42 CFR 110.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Sufficient documentation for eligibility and benefits determinations. 110.72 Section 110.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES COUNTERMEASURES INJURY COMPENSATION PROGRAM Secretarial Determinations...

  8. 42 CFR 110.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Sufficient documentation for eligibility and benefits determinations. 110.72 Section 110.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES COUNTERMEASURES INJURY COMPENSATION PROGRAM Secretarial Determinations...

  9. 42 CFR 110.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Sufficient documentation for eligibility and benefits determinations. 110.72 Section 110.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES COUNTERMEASURES INJURY COMPENSATION PROGRAM Secretarial Determinations...

  10. 42 CFR 110.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Sufficient documentation for eligibility and benefits determinations. 110.72 Section 110.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES COUNTERMEASURES INJURY COMPENSATION PROGRAM Secretarial Determinations...

  11. 24 CFR 984.306 - Section 8 residency and portability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Section 8 residency and portability requirements. 984.306 Section 984.306 Housing and Urban Development Regulations Relating to Housing and Urban...

  12. 14 CFR 252.7 - No-smoking sections.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false No-smoking sections. 252.7 Section 252.7... REGULATIONS SMOKING ABOARD AIRCRAFT § 252.7 No-smoking sections. (a) Except as provided in paragraph (b) of... shall provide, at a minimum: (1) A no-smoking section for each class of service; (2) A sufficient number...

  13. 14 CFR 252.7 - No-smoking sections.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false No-smoking sections. 252.7 Section 252.7... REGULATIONS SMOKING ABOARD AIRCRAFT § 252.7 No-smoking sections. (a) Except as provided in paragraph (b) of... shall provide, at a minimum: (1) A no-smoking section for each class of service; (2) A sufficient number...

  14. 14 CFR 252.7 - No-smoking sections.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false No-smoking sections. 252.7 Section 252.7... REGULATIONS SMOKING ABOARD AIRCRAFT § 252.7 No-smoking sections. (a) Except as provided in paragraph (b) of... shall provide, at a minimum: (1) A no-smoking section for each class of service; (2) A sufficient number...

  15. 14 CFR 252.7 - No-smoking sections.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false No-smoking sections. 252.7 Section 252.7... REGULATIONS SMOKING ABOARD AIRCRAFT § 252.7 No-smoking sections. (a) Except as provided in paragraph (b) of... shall provide, at a minimum: (1) A no-smoking section for each class of service; (2) A sufficient number...

  16. 14 CFR 252.7 - No-smoking sections.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false No-smoking sections. 252.7 Section 252.7... REGULATIONS SMOKING ABOARD AIRCRAFT § 252.7 No-smoking sections. (a) Except as provided in paragraph (b) of... shall provide, at a minimum: (1) A no-smoking section for each class of service; (2) A sufficient number...

  17. 42 CFR 102.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Sufficient documentation for eligibility and benefits determinations. 102.72 Section 102.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Secretarial Determinations § 102.72...

  18. 42 CFR 102.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Sufficient documentation for eligibility and benefits determinations. 102.72 Section 102.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Secretarial Determinations § 102.72...

  19. 42 CFR 102.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Sufficient documentation for eligibility and benefits determinations. 102.72 Section 102.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Secretarial Determinations § 102.72...

  20. 42 CFR 102.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Sufficient documentation for eligibility and benefits determinations. 102.72 Section 102.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Secretarial Determinations § 102.72...

  1. 42 CFR 102.72 - Sufficient documentation for eligibility and benefits determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Sufficient documentation for eligibility and benefits determinations. 102.72 Section 102.72 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Secretarial Determinations § 102.72...

  2. Theoretical Calculation of Viscous-Inviscid Transonic Flows.

    DTIC Science & Technology

    1980-08-01

    Taylor Naval Ship Research and Development Center Aviation and Surface Effects Department / (See reverse side) Bethesda, Maryland 20084 ! CONTROLLING...Interactions ... .......... ... 46 18 -ffect of Boundary Layer on Blade Surface Pressures in a Transonic Fan Rotor Tip Section Cascade...complicated by the viscous effect . The strong viscous-inviscid interaction caused by the shock wave thickens the boundary layer rapidly, and the flow eventually

  3. 17 CFR 36.2 - Exempt boards of trade.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

  4. 17 CFR 36.2 - Exempt boards of trade.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

  5. 17 CFR 36.2 - Exempt boards of trade.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 36.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXEMPT MARKETS § 36.2... deliverable supply; (ii) A deliverable supply that is sufficiently large, and a cash market sufficiently... manipulation; or (iii)No cash market. (2) The commodities that meet the criteria of paragraph (a)(1) of this...

  6. 75 FR 39035 - Housing Choice Voucher (HCV) Family Self-Sufficiency (FSS) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ...) Family Self-Sufficiency (FSS) Program AGENCY: Office of the Chief Information Officer, HUD. ACTION... Department is soliciting public comments on the subject proposal. The FSS program, which was established in... coordinate the use of public housing assistance and assistance under the Section 8 rental certificate and...

  7. 33 CFR 207.260 - Yazoo Diversion Canal, Vicksburg, Miss., from its mouth at Kleinston Landing to Fisher Street...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... unless the logs float sufficiently high in the water to make it evident that the section will not sink en... 300 feet they shall be handled by two tugs; and in all cases they must be handled by sufficient tug...

  8. 33 CFR 207.260 - Yazoo Diversion Canal, Vicksburg, Miss., from its mouth at Kleinston Landing to Fisher Street...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... unless the logs float sufficiently high in the water to make it evident that the section will not sink en... 300 feet they shall be handled by two tugs; and in all cases they must be handled by sufficient tug...

  9. 33 CFR 207.260 - Yazoo Diversion Canal, Vicksburg, Miss., from its mouth at Kleinston Landing to Fisher Street...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... unless the logs float sufficiently high in the water to make it evident that the section will not sink en... 300 feet they shall be handled by two tugs; and in all cases they must be handled by sufficient tug...

  10. 29 CFR 1910.25 - Portable wood ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... library ladders are not specifically covered by this section. (b) Materials—(1) Requirements applicable to... device of sufficient size and strength to securely hold the front and back sections in open positions...

  11. 29 CFR 1910.25 - Portable wood ladders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... library ladders are not specifically covered by this section. (b) Materials—(1) Requirements applicable to... device of sufficient size and strength to securely hold the front and back sections in open positions...

  12. Particle size effects on uptake of heavy metals from sewage sludge compost using natural zeolite clinoptilolite.

    PubMed

    Zorpas, Antonis A; Vassilis, Inglezakis; Loizidou, Maria; Grigoropoulou, Helen

    2002-06-01

    Land application of sewage sludge may be the least energy consuming and the most cost-effective means of sludge disposal or utilization. However, the major technical problem with land application of sludge concerns the high concentrations of heavy metals. These metals may be leached and enter the ecosystem, the food chain, and eventually the human population. This paper deals with the removal of heavy metals from sewage sludge compost using natural zeolite clinoptilolite, in respect to the particle size. The final results indicate that heavy metals can be sufficiently removed by using 25% w/w of zeolite with particle size of 3.3-4.0 mm. Pore clogging and structural damage in smaller particle sizes is probably the reason for lower uptake of metals by the latter.

  13. On the Economics of Space Colonisation

    NASA Astrophysics Data System (ADS)

    King, D. J.

    An economic model of the future colonisation of Mars is developed, which, for simplicity, is assumed to be a one-off transplantation of capital and population to Mars. The model demonstrates that compound growth of output and population, and diminishing natural resources on Earth eventually create sufficiently intense economic pressures that the colonisation of Mars (and by implication of space generally) confers a net economic benefit on humanity. The model illustrates that the colonisation of space is likely to occur because economic forces will ultimately compel it to occur. The model is highly counter-intuitive because it has traditionally been believed by many that the colonisation of space could only be done at a net economic cost to humanity and would not result in a net economic benefit to mankind.

  14. Interface instabilities during displacements of two miscible fluids in a vertical pipe

    NASA Astrophysics Data System (ADS)

    Scoffoni, J.; Lajeunesse, E.; Homsy, G. M.

    2001-03-01

    We study experimentally the downward vertical displacement of one miscible fluid by another in a vertical pipe at sufficiently high velocities for diffusive effects to be negligible. For certain viscosity ratios and flow rates, the interface between the two fluids can destabilize. We determine the dimensionless flow rate Uc above which the instability is triggered and its dependence on the viscous ratio M, resulting in a stability map Uc=Uc(M). Two different instability modes have been observed: an asymmetric "corkscrew" mode and an axisymmetric one. We remark that the latter is always eventually disturbed by "corkscrew" type instabilities. We speculate that these instabilities are driven by the viscosity stratification and are analogous to those already observed in core annular flows of immiscible fluids.

  15. Tandem repeats of the 5' non-transcribed spacer of Tetrahymena rDNA function as high copy number autonomous replicons in the macronucleus but do not prevent rRNA gene dosage regulation.

    PubMed Central

    Pan, W J; Blackburn, E H

    1995-01-01

    The rRNA genes in the somatic macronucleus of Tetrahymena thermophila are normally on 21 kb linear palindromic molecules (rDNA). We examined the effect on rRNA gene dosage of transforming T.thermophila macronuclei with plasmid constructs containing a pair of tandemly repeated rDNA replication origin regions unlinked to the rRNA gene. A significant proportion of the plasmid sequences were maintained as high copy circular molecules, eventually consisting solely of tandem arrays of origin regions. As reported previously for cells transformed by a construct in which the same tandem rDNA origins were linked to the rRNA gene [Yu, G.-L. and Blackburn, E. H. (1990) Mol. Cell. Biol., 10, 2070-2080], origin sequences recombined to form linear molecules bearing several tandem repeats of the origin region, as well as rRNA genes. The total number of rDNA origin sequences eventually exceeded rRNA gene copies by approximately 20- to 40-fold and the number of circular replicons carrying only rDNA origin sequences exceeded rRNA gene copies by 2- to 3-fold. However, the rRNA gene dosage was unchanged. Hence, simply monitoring the total number of rDNA origin regions is not sufficient to regulate rRNA gene copy number. Images PMID:7784211

  16. Prototypical Organic–Oxide Interface: Intramolecular Resolution of Sexiphenyl on In 2O 3 (111)

    DOE PAGES

    Wagner, Margareta; Hofinger, Jakob; Setvin, Martin; ...

    2018-03-28

    The performance of an organic semiconductor device is critically determined by the geometric alignment, orientation, and ordering of the organic molecules. Although an organic multilayer eventually adopts the crystal structure of the organic material, the alignment and configuration at the interface with the substrate/electrode material are essential for charge injection into the organic layer. This work focuses on the prototypical organic semiconductor para-sexiphenyl (6P) adsorbed on In 2O 3(111), the thermodynamically most stable surface of the material that the most common transparent conducting oxide, indium tin oxide, is based on. The onset of nucleation and formation of the first monolayermore » are followed with atomically resolved scanning tunneling microscopy and noncontact atomic force microscopy (nc-AFM). Annealing to 200 °C provides sufficient thermal energy for the molecules to orient themselves along the high-symmetry directions of the surface, leading to a single adsorption site. The AFM data suggests an essentially planar adsorption geometry. With increasing coverage, the 6P molecules first form a loose network with a poor long-range order. Eventually, the molecules reorient into an ordered monolayer. In conclusion, this first monolayer has a densely packed, well-ordered (2 × 1) structure with one 6P per In 2O 3(111) substrate unit cell, that is, a molecular density of 5.64 × 10 13 cm –2.« less

  17. Gap opening after merger events of 3-Earth-mass protoplanets

    NASA Astrophysics Data System (ADS)

    Broz, Miroslav; Chrenko, Ondrej

    2017-10-01

    While several-Earth-mass protoplanets can gain non-negligible eccentricities due to their interactions with the gaseous disk and ongoing pebble accretion (so called hot trail effect; see the contribution of Chrenko et al. 2017 for details), there is a opened pathway for giant-planet core formation by means of close encounters and eventual merging. As soon as a massive (~13 M_E) merger is formed, it seems necessary to account for one additional term in the set of hydrodynamic equations, namely the gas accretion, which may affect subsequent orbital evolution, and eventually change Type-I migration to Type-II. Using similar approximations as Crida and Bitsch (2017), we prolong our previous simulations towards the onset of gap opening.At the same time, we try to address the observability of these events, e.g. by ALMA in its full configuration. Because the disk is still mostly optically thick in the vertical direction (tau =~ 100), it is necessary to properly model the disk atmosphere. In the midplane, the mean-free path of gas molecules is small enough to assure a sufficient thermal contact and equilibrium between the gas and dust. This is no more true far from the midplane and one has to use a non-equilibrium model (e.g. Radmc-3d code) for the description of dust grain temperatures, resulting synthetic image, or emergent spectrum.

  18. Prototypical Organic–Oxide Interface: Intramolecular Resolution of Sexiphenyl on In 2O 3 (111)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wagner, Margareta; Hofinger, Jakob; Setvin, Martin

    The performance of an organic semiconductor device is critically determined by the geometric alignment, orientation, and ordering of the organic molecules. Although an organic multilayer eventually adopts the crystal structure of the organic material, the alignment and configuration at the interface with the substrate/electrode material are essential for charge injection into the organic layer. This work focuses on the prototypical organic semiconductor para-sexiphenyl (6P) adsorbed on In 2O 3(111), the thermodynamically most stable surface of the material that the most common transparent conducting oxide, indium tin oxide, is based on. The onset of nucleation and formation of the first monolayermore » are followed with atomically resolved scanning tunneling microscopy and noncontact atomic force microscopy (nc-AFM). Annealing to 200 °C provides sufficient thermal energy for the molecules to orient themselves along the high-symmetry directions of the surface, leading to a single adsorption site. The AFM data suggests an essentially planar adsorption geometry. With increasing coverage, the 6P molecules first form a loose network with a poor long-range order. Eventually, the molecules reorient into an ordered monolayer. In conclusion, this first monolayer has a densely packed, well-ordered (2 × 1) structure with one 6P per In 2O 3(111) substrate unit cell, that is, a molecular density of 5.64 × 10 13 cm –2.« less

  19. 76 FR 32200 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-03

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL -9314-7] Notice of a Project Waiver of Section 1605 (Buy... a project waiver of the Buy American requirements of ARRA Section 1605 under the authority of Section 1605(b)(2) [manufactured goods are not produced in the United States in sufficient and reasonably...

  20. 40 CFR 257.21 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... section apply to units identified in § 257.5(a), except as provided in paragraph (b) of this section. (b... engineering and has sufficient training and experience in ground-water hydrology and related fields as may be...

  1. 29 CFR 778.404 - Purposes of exemption.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... exemption. The exception to the requirements of section 7(a) provided by section 7(f) of the Act is designed.... Plans which do not meet these conditions were not thought to provide sufficient advantage to the...

  2. Energy self-sufficiency in Northampton, Massachusetts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The study is not an engineering analysis but begins the process of exploring the potential for conservation and local renewable-resource development in a specific community, Northampton, Massachusetts, with the social, institutional, and environmental factors in that community taken into account. Section I is an extensive executive summary of the full study, and Section II is a detailed examination of the potential for increased local energy self-sufficiency in Northampton, including current and future demand estimates, the possible role of conservation and renewable resources, and a discussion of the economic and social implications of alternative energy systems. (MOW)

  3. Variation in Protein and Calorie Consumption Following Protein Malnutrition in Rattus norvegicus

    PubMed Central

    Jones, Donna C.; German, Rebecca Z.

    2013-01-01

    Simple Summary Catch-up growth following malnutrition is likely influenced by available protein and calories. We measured calorie and protein consumption following the removal of protein malnutrition after 40, 60 and 90 days, in laboratory rats. Following the transition in diet, animals self-selected fewer calories, implying elevated protein is sufficient to fuel catch-up growth, eventually resulting in body weights and bone lengths greater or equal to those of control animals. Rats rehabilitated at younger ages, had more drastic alterations in consumption. Variable responses in different ages and sex highlight the plasticity of growth and how nutrition affects body form. This work furthers our understanding of how humans and livestock can recover from protein-restriction malnutrition, which seems to employ different biological responses. Abstract Catch-up growth rates, following protein malnutrition, vary with timing and duration of insult, despite unlimited access to calories. Understanding changing patterns of post-insult consumption, relative rehabilitation timing, can provide insight into the mechanisms driving those differences. We hypothesize that higher catch-up growth rates will be correlated with increased protein consumption, while calorie consumption could remain stable. As catch-up growth rates decrease with age/malnutrition duration, we predict a dose effect in protein consumption with rehabilitation timing. We measured total and protein consumption, body mass, and long bone length, following an increase of dietary protein at 40, 60 and 90 days, with two control groups (chronic reduced protein or standard protein) for 150+ days. Immediately following rehabilitation, rats’ food consumption decreased significantly, implying that elevated protein intake is sufficient to fuel catch-up growth rates that eventually result in body weights and long bone lengths greater or equal to final measures of chronically fed standard (CT) animals. The duration of protein restriction affected consumption: rats rehabilitated at younger ages had more drastic alterations in consumption of both calories and protein. While rehabilitated animals did compensate with greater protein consumption, variable responses in different ages and sex highlight the plasticity of growth and how nutrition affects body form. PMID:26487308

  4. 75 FR 10258 - Notice of a Project Waiver of Section 1605: (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9118-9] Notice of a Project Waiver of Section 1605: (Buy... granting a project waiver of the Buy American requirements of ARRA Section 1605(a) under the authority of Section 1605(b)(2) (manufactured goods are not produced in the United States in sufficient and reasonably...

  5. 76 FR 2371 - Notice of a Regional Project Waiver of Section 1605 (Buy American) of the American Recovery and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9252-6] Notice of a Regional Project Waiver of Section 1605... hereby granting a waiver of the Buy American requirements of ARRA Section 1605 under the authority of Section 1605(b)(2) [manufactured goods are not produced in the United States in sufficient and reasonably...

  6. 76 FR 37350 - Notice of a Regional Project Waiver of Section 1605 (Buy American) of the American Recovery and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... Waiver of Section 1605 (Buy American) of the American Recovery and Reinvestment Act of 2009 (ARRA) to the... hereby granting a waiver of the Buy American requirements of ARRA Section 1605 under the authority of Section 1605(b) (2) [manufactured goods are not produced in the United States in sufficient and reasonably...

  7. A study of commuter air service

    NASA Technical Reports Server (NTRS)

    Belina, F. W.; Bush, L. R.

    1977-01-01

    A regionally oriented overview of the commuter air service industry is provided. A framework for an eventual assessment of potential technology directions that may be of benefit to the industry is presented. Data are provided on the industry's market characteristics, service patterns, patronage characteristics, aircraft and airport needs, economic characteristics and institutional issues. Using personal interview and literature survey methods, investigation of a considerable cross-section of the industry was made.

  8. Effects of porosity on shock-induced melting of honeycomb-shaped Cu nanofoams

    NASA Astrophysics Data System (ADS)

    Zhao, Fengpeng

    Metallic foams are of fundamental and applied interests in various areas, including structure engineering (e.g., lightweight structural members and energy absorbers), and shock physics (e.g., as laser ablators involving shock-induced melting and vaporization).Honeycomb-shaped metallic foams consist of regular array of hexagonal cells in two dimensions and have extensive applications and represent a unique, simple yet useful model structure for exploring mechanisms and making quantitative assessment. We investigate shock-induced melting in honeycomb-shaped Cu nanofoams with extensive molecular dynamics simulations. A total of ten porosities (phi) are explored, ranging from 0 to 0.9 at an increment of 0.1. Upon shock compression, void collapse induces local melting followed by supercooling for sufficiently high porosity at low shock strengths. While superheating of solid remnants occurs for sufficiently strong shocks at phi<0.1. Both supercooling of melts and superheating of solid remnants are transient, and the equilibrated shock states eventually fall on the equilibrium melting curve for partial melting. However, phase equilibrium has not been achieved on the time scale of simulations in supercooled Cu liquid (from completely melted nanofoams). The temperatures for incipient and complete melting are related to porosity via a power law and approach the melting temperature at zero pressure as phi tends to 1.

  9. The Sydney Blood Bank Cohort: implications for viral fitness as a cause of elite control.

    PubMed

    Zaunders, John; Dyer, Wayne B; Churchill, Melissa

    2011-05-01

    The Sydney Blood Bank Cohort comprised eight individuals who were infected with an attenuated, nef/LTR-deleted strain of HIV-1 from a single donor. All six recipients with sufficient follow-up, as well as the donor, were long-term nonprogressors. Only three recipients have maintained undetectable plasma viral loads, allowing investigation of factors that determined elite control of attenuated HIV-1 infection. Follow-up of recipients showed that infection with this attenuated HIV-1 strain resulted in either low or absent viral replication in vivo for up to 29 years. The three patients without detectable viraemia have been studied for virological, genetic and immunological correlates of elite control. CD4 proliferation in vitro in response to p24 provided the clearest distinction of elite controllers from the slow progressors. Host factors are believed to differentiate the three elite controllers; only one, C135, has identifiable genetic polymorphisms that probably contributed to nonprogression: Δ32 CCR5 heterozygosity, HLA-B57 and HLA-DR13 alleles, in addition to infection with nef-defective HIV-1. Even nef-defective HIV-1 can lead to sufficient replication in vivo to enable viral evolution and eventual progression to immunodeficiency. Host factors modified the outcome of infection with attenuated HIV-1, as exemplified by the unique patient C135.

  10. Molecular Divergence and Species Delimitation of the Cultivated Oyster Mushrooms: Integration of IGS1 and ITS

    PubMed Central

    Bhassu, Subha; Tan, Yee Shin; Vikineswary, Sabaratnam

    2014-01-01

    Identification of edible mushrooms particularly Pleurotus genus has been restricted due to various obstacles. The present study attempted to use the combination of two variable regions of IGS1 and ITS for classifying the economically cultivated Pleurotus species. Integration of the two regions proved a high ability that not only could clearly distinguish the species but also served sufficient intraspecies variation. Phylogenetic tree (IGS1 + ITS) showed seven distinct clades, each clade belonging to a separate species group. Moreover, the species differentiation was tested by AMOVA and the results were reconfirmed by presenting appropriate amounts of divergence (91.82% among and 8.18% within the species). In spite of achieving a proper classification of species by combination of IGS1 and ITS sequences, the phylogenetic tree showed the misclassification of the species of P. nebrodensis and P. eryngii var. ferulae with other strains of P. eryngii. However, the constructed median joining (MJ) network could not only differentiate between these species but also offer a profound perception of the species' evolutionary process. Eventually, due to the sufficient variation among and within species, distinct sequences, simple amplification, and location between ideal conserved ribosomal genes, the integration of IGS1 and ITS sequences is recommended as a desirable DNA barcode. PMID:24587752

  11. 3D Reconstruction of Chick Embryo Vascular Geometries Using Non-invasive High-Frequency Ultrasound for Computational Fluid Dynamics Studies.

    PubMed

    Tan, Germaine Xin Yi; Jamil, Muhammad; Tee, Nicole Gui Zhen; Zhong, Liang; Yap, Choon Hwai

    2015-11-01

    Recent animal studies have provided evidence that prenatal blood flow fluid mechanics may play a role in the pathogenesis of congenital cardiovascular malformations. To further these researches, it is important to have an imaging technique for small animal embryos with sufficient resolution to support computational fluid dynamics studies, and that is also non-invasive and non-destructive to allow for subject-specific, longitudinal studies. In the current study, we developed such a technique, based on ultrasound biomicroscopy scans on chick embryos. Our technique included a motion cancelation algorithm to negate embryonic body motion, a temporal averaging algorithm to differentiate blood spaces from tissue spaces, and 3D reconstruction of blood volumes in the embryo. The accuracy of the reconstructed models was validated with direct stereoscopic measurements. A computational fluid dynamics simulation was performed to model fluid flow in the generated construct of a Hamburger-Hamilton (HH) stage 27 embryo. Simulation results showed that there were divergent streamlines and a low shear region at the carotid duct, which may be linked to the carotid duct's eventual regression and disappearance by HH stage 34. We show that our technique has sufficient resolution to produce accurate geometries for computational fluid dynamics simulations to quantify embryonic cardiovascular fluid mechanics.

  12. Electric field driven evolution of topological domain structure in hexagonal manganites

    NASA Astrophysics Data System (ADS)

    Yang, K. L.; Zhang, Y.; Zheng, S. H.; Lin, L.; Yan, Z. B.; Liu, J.-M.; Cheong, S.-W.

    2017-10-01

    Controlling and manipulating the topological state represents an important topic in condensed matters for both fundamental researches and applications. In this work, we focus on the evolution of a real-space topological domain structure in hexagonal manganites driven by electric field, using the analytical and numerical calculations based on the Ginzburg-Landau theory. It is revealed that the electric field drives a transition of the topological domain structure from the type-I pattern to the type-II one. In particular, it is identified that a high electric field can enforce the two antiphase-plus-ferroelectric (AP +FE ) domain walls with Δ Φ =π /3 to approach each other and to merge into one domain wall with Δ Φ = 2 π /3 eventually if the electric field is sufficiently high, where Δ Φ is the difference in the trimerization phase between two neighboring domains. Our simulations also reveal that the vortex cores of the topological structure can be disabled at a sufficiently high critical electric field by suppressing the structural trimerization therein, beyond which the vortex core region is replaced by a single ferroelectric domain without structural trimerization (Q = 0 ). Our results provide a stimulating reference for understanding the manipulation of real-space topological domain structure in hexagonal manganites.

  13. Some thoughts on the diffusion of psychoanalysis: the group dimension, ethics and the sense of identity.

    PubMed

    Namer, Albert

    2011-12-01

    In this paper the author questions some of the ways in which psychoanalysis is passed on to the wider public, one of which is sometimes evocative of the sales promotion of a consumer product in contemporary society. This methodology does not give sufficiently deep prior thought to the eventual consequences of side effects. The detailed exposition of clinical cases, for example, raises sensitive ethical issues, even when anonymity is preserved. Although it is true that making information about Freud's theories more widely available may indeed encourage people to think about training as psychoanalysts, it is noticeable that this process is sometimes considered to be a form of training in itself. Some participants feel that acquiring a psychoanalytical vocabulary and reading clinical reports form a sufficient basis for practising thereafter as psychotherapists, both in institutional contexts and in private practice. The absence of group work on the part of the organizers might explain why closer study is not made of the methodologies of transmission and the different levels that it involves. This is sometimes due to the absence of a common object, formed within and by the group, and to the emergence of manic defences in the group. Copyright © 2011 Institute of Psychoanalysis.

  14. Excitation of Crossflow Instabilities in a Swept Wing Boundary Layer

    NASA Technical Reports Server (NTRS)

    Carpenter, Mark H.; Choudhari, Meelan; Li, Fei; Streett, Craig L.; Chang, Chau-Lyan

    2010-01-01

    The problem of crossflow receptivity is considered in the context of a canonical 3D boundary layer (viz., the swept Hiemenz boundary layer) and a swept airfoil used recently in the SWIFT flight experiment performed at Texas A&M University. First, Hiemenz flow is used to analyze localized receptivity due to a spanwise periodic array of small amplitude roughness elements, with the goal of quantifying the effects of array size and location. Excitation of crossflow modes via nonlocalized but deterministic distribution of surface nonuniformity is also considered and contrasted with roughness induced acoustic excitation of Tollmien-Schlichting waves. Finally, roughness measurements on the SWIFT model are used to model the effects of random, spatially distributed roughness of sufficiently small amplitude with the eventual goal of enabling predictions of initial crossflow disturbance amplitudes as functions of surface roughness parameters.

  15. Rumen bacteria: interaction with particulate dietary components and response to dietary variation.

    PubMed

    Cheng, K J; Akin, D E; Costerton, J W

    1977-02-01

    The bovine rumen resembles many other ecosystems in that its component bacterial cells are universally surrounded and protected by extracellular structures. The most common form of these structures is a fibrous carbohydrate slime that extends away from the cell and may mediate the attachment of the bacterium to a surface. This attachment is relatively specific and it may occur at the surface of the rumen epithelium or on the cell walls of a specific tissue within the plant-derived food of the animal. The production of the extracellular slime is under nutritional control and slime may be overproduced when soluble carbohydrates are available in high concentration. This overproduction results in cell-cell adhesion among the rumen bacteria with the eventual formation of slime-enclosed microcolonies and, in extreme cases, the generation of sufficient viscosity to cause feedlot bloat.

  16. Delensing CMB polarization with external datasets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Kendrick M.; Hanson, Duncan; LoVerde, Marilena

    2012-06-01

    One of the primary scientific targets of current and future CMB polarization experiments is the search for a stochastic background of gravity waves in the early universe. As instrumental sensitivity improves, the limiting factor will eventually be B-mode power generated by gravitational lensing, which can be removed through use of so-called ''delensing'' algorithms. We forecast prospects for delensing using lensing maps which are obtained externally to CMB polarization: either from large-scale structure observations, or from high-resolution maps of CMB temperature. We conclude that the forecasts in either case are not encouraging, and that significantly delensing large-scale CMB polarization requires high-resolutionmore » polarization maps with sufficient sensitivity to measure the lensing B-mode. We also present a simple formalism for including delensing in CMB forecasts which is computationally fast and agrees well with Monte Carlos.« less

  17. Secular evolution of eccentricity in protoplanetary discs with gap-opening planets

    NASA Astrophysics Data System (ADS)

    Teyssandier, Jean; Ogilvie, Gordon I.

    2017-06-01

    We explore the evolution of the eccentricity of an accretion disc perturbed by an embedded planet whose mass is sufficient to open a large gap in the disc. Various methods for representing the orbit-averaged motion of an eccentric disc are discussed. We characterize the linear instability that leads to the growth of eccentricity by means of hydrodynamical simulations. We numerically recover the known result that eccentricity growth in the disc is possible when the planet-to-star mass ratio exceeds 3 × 10-3. For mass ratios larger than this threshold, the precession rates and growth rates derived from simulations, as well as the shape of the eccentric mode, compare well with the predictions of a linear theory of eccentric discs. We study mechanisms by which the eccentricity growth eventually saturates into a non-linear regime.

  18. Raising more domestic money for health: prospects for low- and middle-income countries.

    PubMed

    Elovainio, Riku; Evans, David B

    2017-04-01

    Since the 2007/2008 financial crisis, the rhetoric in the development assistance dialogue has shifted away from raising more international funding for health, to requesting countries to move toward self-sufficiency. This paper examines the potential of 46 countries identified by an international panel in 2009 as being of high need to raise additional funding for health from domestic sources. Economic growth alone would allow 12 of them to reach a level of health spending where their populations could have access to a very basic set of health services. All of them have the potential to raise additional domestic funds through a range of measures that have been tried successfully in other low- and middle-income countries, but they would all remain well below the eventual objective of universal health coverage without increased and predictable external financial support.

  19. Hypersonic Research Vehicle (HRV) real-time flight test support feasibility and requirements study. Part 2: Remote computation support for flight systems functions

    NASA Technical Reports Server (NTRS)

    Rediess, Herman A.; Hewett, M. D.

    1991-01-01

    The requirements are assessed for the use of remote computation to support HRV flight testing. First, remote computational requirements were developed to support functions that will eventually be performed onboard operational vehicles of this type. These functions which either cannot be performed onboard in the time frame of initial HRV flight test programs because the technology of airborne computers will not be sufficiently advanced to support the computational loads required, or it is not desirable to perform the functions onboard in the flight test program for other reasons. Second, remote computational support either required or highly desirable to conduct flight testing itself was addressed. The use is proposed of an Automated Flight Management System which is described in conceptual detail. Third, autonomous operations is discussed and finally, unmanned operations.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gim, Yongwan; Kim, Wontae, E-mail: yongwan89@sogang.ac.kr, E-mail: wtkim@sogang.ac.kr

    In warm inflation scenarios, radiation always exists, so that the radiation energy density is also assumed to be finite when inflation starts. To find out the origin of the non-vanishing initial radiation energy density, we revisit thermodynamic analysis for a warm inflation model and then derive an effective Stefan-Boltzmann law which is commensurate with the temperature-dependent effective potential by taking into account the non-vanishing trace of the total energy-momentum tensors. The effective Stefan-Boltzmann law shows that the zero energy density for radiation at the Grand Unification epoch increases until the inflation starts and it becomes eventually finite at the initialmore » stage of warm inflation. By using the above effective Stefan-Boltzmann law, we also study the cosmological scalar perturbation, and obtain the sufficient radiation energy density in order for GUT baryogenesis at the end of inflation.« less

  1. Space Sciences Laboratory Publications and Presentations

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    1998-01-01

    This document lists the significant publications and presentations of the Space Sciences Laboratory during the period January 1 - December 31, 1997. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an Appendix (arranged by page number) listing preprints issued by the Laboratory during this reporting period. Some of the preprints have not been published; those already published are so indicated. Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

  2. Geometric constrained variational calculus. III: The second variation (Part II)

    NASA Astrophysics Data System (ADS)

    Massa, Enrico; Luria, Gianvittorio; Pagani, Enrico

    2016-03-01

    The problem of minimality for constrained variational calculus is analyzed within the class of piecewise differentiable extremaloids. A fully covariant representation of the second variation of the action functional based on a family of local gauge transformations of the original Lagrangian is proposed. The necessity of pursuing a local adaptation process, rather than the global one described in [1] is seen to depend on the value of certain scalar attributes of the extremaloid, here called the corners’ strengths. On this basis, both the necessary and the sufficient conditions for minimality are worked out. In the discussion, a crucial role is played by an analysis of the prolongability of the Jacobi fields across the corners. Eventually, in the appendix, an alternative approach to the concept of strength of a corner, more closely related to Pontryagin’s maximum principle, is presented.

  3. Heavy Ion Formation in Titan's Ionosphere: Magnetospheric Introduction of Free Oxygen and Source of Titan's Aerosols?

    NASA Technical Reports Server (NTRS)

    Sittler, E. C., Jr.; Hartle, R. E.; Cooper, J. F.; Johnson, R. E.; Coates, A.; dePater, imke; Strom, Daphne; Simoes, F.; Steele, A.; Robb, F.

    2007-01-01

    With the recent discovery of heavy ions, positive and negative, by the Cassini Plasma Spectrometer (CAPS) instrument in Titan's ionosphere, it reveals new possibilities for aerosol formation at Titan and the introduction of free oxygen to the aerosol chemistry from Saturn's magnetosphere with Enceladus as the primary oxygen source. One can estimate whether the heavy ions in the ionosphere are of sufficient number to account for all the aerosols, under what conditions are favorable for heavy ion formation and how they are introduced as seed particles deeper in Titan's atmosphere where the aerosols form and eventually find themselves on Titan's surface where unknown chemical processes can take place. Finally, what are the possibilities with regard to their chemistry on the surface with some free oxygen present in their seed particles?

  4. Science Directorate Publications and Presentations, January 1 - December 31, 2003

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2004-01-01

    This Technical Memorandum (TM) lists the significant publications and presentations of the Science Directorate during the period January 1 - December 31, 2003. Entries in the main part of the TM are categorized according to NASA Reports (arranged by report number), Open Literature and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. Questions or requests for additional information about the entries in this TM should be directed to Dr. A.F. Whitaker (SD01; 544-2481) or to one of the authors.

  5. Space resources. Volume 4: Social concerns

    NASA Technical Reports Server (NTRS)

    Mckay, Mary Fae (Editor); Mckay, David S. (Editor); Duke, Michael B. (Editor)

    1992-01-01

    Space resources must be used to support life on the Moon and exploration of Mars. This volume, Social Concerns, covers some of the most important issues which must be addressed in any major program for the human exploration of space. The volume begins with a consideration of the economics and management of large scale space activities. Then the legal aspects of these activities are discussed, particularly the interpretation of treaty law with respect to the Moon and asteroids. The social and cultural issues of moving people into space are considered in detail, and the eventual emergence of a space culture different from the existing culture is envisioned. The environmental issues raised by the development of space settlements are faced. Some innovative approaches are proposed to space communities and habitats and self-sufficiency is considered along with human safety at a lunar base or outpost.

  6. The evaluation of experimental data in fast range for n + 56Fe(n,inl)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qian, Jing; Herman, M.; Ge, Zhigang

    Iron is one of the five materials selected for evaluation within the pilot international evaluation project CIELO. Analysis of experimental data for n+ 56Fe reaction is the basis for constraining theoretical calculations and eventual creation of the evaluated file. The detail analysis was performed for inelastic cross sections of neutron induced reactions with 56Fe in the fast range up to 20 MeV where there are significant differences among the main evaluated libraries, mainly caused by the different inelastic scattering cross section measurements. Gamma-ray production cross sections provide a way to gain experimental information about the inelastic cross section. Large discrepanciesmore » between experimental data for the 847-keV gamma ray produced in the 56Fe(n,n 1'γ) reaction were analyzed. In addition, experimental data for elastic scattering cross section between 9.41~11 MeV were used to deduce the inelastic cross section from the unitarity constrain.« less

  7. The evaluation of experimental data in fast range for n + 56Fe(n,inl)

    DOE PAGES

    Qian, Jing; Herman, M.; Ge, Zhigang; ...

    2017-09-13

    Iron is one of the five materials selected for evaluation within the pilot international evaluation project CIELO. Analysis of experimental data for n+ 56Fe reaction is the basis for constraining theoretical calculations and eventual creation of the evaluated file. The detail analysis was performed for inelastic cross sections of neutron induced reactions with 56Fe in the fast range up to 20 MeV where there are significant differences among the main evaluated libraries, mainly caused by the different inelastic scattering cross section measurements. Gamma-ray production cross sections provide a way to gain experimental information about the inelastic cross section. Large discrepanciesmore » between experimental data for the 847-keV gamma ray produced in the 56Fe(n,n 1'γ) reaction were analyzed. In addition, experimental data for elastic scattering cross section between 9.41~11 MeV were used to deduce the inelastic cross section from the unitarity constrain.« less

  8. The Family Self-Sufficiency Program: HUD's Best Kept Secret for Promoting Employment and Asset Growth.

    ERIC Educational Resources Information Center

    Sard, Barbara

    This paper describes the Family Self-Sufficiency (FSS) program, an employment and savings incentive program for low-income families that have Section 8 vouchers or live in public housing. It consists of both case management services to help participants pursue employment and other goals and escrow accounts into which the public housing agency…

  9. An independent jury-based consensus conference model for the development of recommendations in medico-surgical practice.

    PubMed

    Lesurtel, Mickaël; Perrier, Arnaud; Bossuyt, Patrick M M; Langer, Bernard; Clavien, Pierre-Alain

    2014-03-01

    There is an increasing demand for standardization in the choice of treatments for specific conditions, so-called personalized medicine. The task is far from trivial, because the perspectives from many stakeholders must be respected, including patients and health care providers, as well as payers or governments to better control costs while optimizing quality of care. One approach to provide widely accepted therapies is the consensus conference. We describe a novel methodology to achieve consensus in controversial areas with the main goal to minimize biases. The principle of this approach relies on a clear distinction between those who provide the evidence (experts) and those who draw the final recommendations (the jury). The jury consists of individuals with sufficient background knowledge to cover the perspectives of all stakeholders' without being involved directly in the topic under evaluation. The organizing committee, the experts, and the jury interact within 3 phases: Preparation, the actual consensus conference, and deliberations. Each question is addressed by a panel of experts, leading to the proposition of recommendations at the conference meeting, which are challenged by the jury and the audience. Based on all available information, the jury finalizes the consensus recommendations, which are eventually published and made available to all. This novel model of consensus conference allows the construction of consensual, evidence-based, explicit recommendations for therapies in a process that may also identify issues for further research, eventually fostering progress in the field. Copyright © 2014 Mosby, Inc. All rights reserved.

  10. Asymptotic form for the cross section for the Coulomb interacting rearrangement collisions.

    NASA Technical Reports Server (NTRS)

    Omidvar, K.

    1973-01-01

    It is shown that in a rearrangement collision leading to the formation of highly excited hydrogenlike states the cross section at high energies behaves as 1/n-squared, with n the principal quantum number, thus invalidating the Brinkman-Kramers approximation for large n. Similarly, in high-energy inelastic electron-hydrogenlike-atom collisions the exchange cross section for sufficiently large n dominates the direct excitation cross section.

  11. Erich Fromm's Involvement With Zen Buddhism: Psychoanalysts and the Spiritual Quest in Subsequent Decades.

    PubMed

    Roland, Alan

    2017-08-01

    The first section of this paper covers Erich Fromm's profound involvement with Zen Buddhism, culminating in his co-authoring the book Zen Buddhism and Psychoanalysis in 1960. It details why this was a groundbreaking endeavor, as it countered the pervasive psychoanalytic denigration of spiritual traditions, practices, and experiences. The second section describes the effect of Fromm's Zen Buddhism and Psychoanalysis on the author of this paper, as he came to clinical psychology and psychoanalysis from involvement in Indian philosophy. The third section is a case study of a spiritually advanced Hindu woman seen in intensive short-term psychoanalytic therapy in Bombay, describing the interface of the spiritual with psychoanalytic therapy. The fourth section explains what eventually led to a sea change in psychoanalytic attitudes toward spiritual traditions and practices, with a small but significant group of psychoanalysts becoming involved in one or another spiritual practice, and working with patients also so involved.

  12. 24 CFR 984.302 - Administrative fees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Administrative fees. 984.302 Section 984.302 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.302...

  13. 24 CFR 984.302 - Administrative fees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Administrative fees. 984.302 Section 984.302 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.302...

  14. 24 CFR 984.302 - Administrative fees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Administrative fees. 984.302 Section 984.302 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.302...

  15. 24 CFR 984.302 - Administrative fees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Administrative fees. 984.302 Section 984.302 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.302...

  16. 24 CFR 984.302 - Administrative fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.302... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Administrative fees. 984.302 Section 984.302 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  17. 24 CFR 984.301 - Program implementation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Operation § 984.301 Program... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Program implementation. 984.301 Section 984.301 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  18. Twisted versus braided magnetic flux ropes in coronal geometry. II. Comparative behaviour

    NASA Astrophysics Data System (ADS)

    Prior, C.; Yeates, A. R.

    2016-06-01

    Aims: Sigmoidal structures in the solar corona are commonly associated with magnetic flux ropes whose magnetic field lines are twisted about a mutual axis. Their dynamical evolution is well studied, with sufficient twisting leading to large-scale rotation (writhing) and vertical expansion, possibly leading to ejection. Here, we investigate the behaviour of flux ropes whose field lines have more complex entangled/braided configurations. Our hypothesis is that this internal structure will inhibit the large-scale morphological changes. Additionally, we investigate the influence of the background field within which the rope is embedded. Methods: A technique for generating tubular magnetic fields with arbitrary axial geometry and internal structure, introduced in part I of this study, provides the initial conditions for resistive-MHD simulations. The tubular fields are embedded in a linear force-free background, and we consider various internal structures for the tubular field, including both twisted and braided topologies. These embedded flux ropes are then evolved using a 3D MHD code. Results: Firstly, in a background where twisted flux ropes evolve through the expected non-linear writhing and vertical expansion, we find that flux ropes with sufficiently braided/entangled interiors show no such large-scale changes. Secondly, embedding a twisted flux rope in a background field with a sigmoidal inversion line leads to eventual reversal of the large-scale rotation. Thirdly, in some cases a braided flux rope splits due to reconnection into two twisted flux ropes of opposing chirality - a phenomenon previously observed in cylindrical configurations. Conclusions: Sufficiently complex entanglement of the magnetic field lines within a flux rope can suppress large-scale morphological changes of its axis, with magnetic energy reduced instead through reconnection and expansion. The structure of the background magnetic field can significantly affect the changing morphology of a flux rope.

  19. Supervised Injectable Heroin: A Clinical Perspective.

    PubMed

    Bell, James; Waal, Rob van der; Strang, John

    2017-07-01

    Six recent randomised control trials (RCTs) have suggested that supervised injectable heroin (SIH) can be effective in patients who persist in street heroin use during methadone treatment. However, short-term randomised control trials have limitations in assessing the effectiveness of treatments for addictive disorders, which are chronic and relapsing disorders of motivation. These RCTs particularly fail to capture the process of the SIH treatment and the diversity of influence and change over time. This narrative review is based on the analysis of published data. Conclusions are drawn from a process of reflection informed by experience in delivering one of the published trials, subsequent experiences in varying the way SIH is delivered, and through consideration of possible mechanisms of action of SIH. Many long-term, socially marginalised and demoralised people who are addicted to heroin experience few rewards from the stability afforded by methadone treatment. Supervised injected heroin is sufficiently reinforcing for many of these individuals to attend daily and participate in highly structured treatment. With an adequate daily dose of supervised methadone to avoid withdrawal dysphoria, occasional diamorphine injections-not necessarily twice daily, or even every day-is enough to hold people in treatment. Participation was associated with reduced amounts of non-prescribed drug use, a gradual change in self-image and attitude, and for some subjects, a movement towards social reintegration and eventual withdrawal from SIH. Prescribed heroin is sufficiently motivating to hold a proportion of recidivist addicts in long-term treatment. Participation in structured treatment provides respite from compulsive drug use, and a proportion of subjects develop sufficient rewards from social reintegration to successfully withdraw from treatment. Such change, when it occurs, is slow and stuttering.

  20. Critical gravitational collapse with angular momentum. II. Soft equations of state

    NASA Astrophysics Data System (ADS)

    Gundlach, Carsten; Baumgarte, Thomas W.

    2018-03-01

    We study critical phenomena in the collapse of rotating ultrarelativistic perfect fluids, in which the pressure P is related to the total energy density ρ by P =κ ρ , where κ is a constant. We generalize earlier results for radiation fluids with κ =1 /3 to other values of κ , focusing on κ <1 /9 . For 1 /9 <κ ≲0.49 , the critical solution has only one unstable, growing mode, which is spherically symmetric. For supercritical data it controls the black-hole mass, while for subcritical data it controls the maximum density. For κ <1 /9 , an additional axial l =1 mode becomes unstable. This controls either the black-hole angular momentum, or the maximum angular velocity. In theory, the additional unstable l =1 mode changes the nature of the black-hole threshold completely: at sufficiently large initial rotation rates Ω and sufficient fine-tuning of the initial data to the black-hole threshold we expect to observe nontrivial universal scaling functions (familiar from critical phase transitions in thermodynamics) governing the black-hole mass and angular momentum, and, with further fine-tuning, eventually a finite black-hole mass almost everywhere on the threshold. In practice, however, the second unstable mode grows so slowly that we do not observe this breakdown of scaling at the level of fine-tuning we can achieve, nor systematic deviations from the leading-order power-law scalings of the black-hole mass. We do see systematic effects in the black-hole angular momentum, but it is not clear yet if these are due to the predicted nontrivial scaling functions, or to nonlinear effects at sufficiently large initial angular momentum (which we do not account for in our theoretical model).

  1. Report on cancer risks associated with the ingestion of asbestos. DHHS Committee to Coordinate Environmental and Related Programs.

    PubMed Central

    1987-01-01

    This report is an assessment of all available literature that pertains to the potential risk of cancer associated with ingestion of asbestos. It was compiled by a working group to assist policy makers in the Department of Health and Human Services determine if adequate information was available for a definitive risk assessment on this potential problem and evaluate if the weight of evidence was sufficient to prioritize this issue for new policy recommendations. The work group considered the basis for concern over this problem, the body of toxicology experiments, the individual epidemiologic studies which have attempted to investigate this issue, and the articles that discuss components of risk assessment pertaining to the ingestion of asbestos. In the report, the work group concluded: that no direct, definitive risk assessment can be conducted at this time; that further epidemiologic investigations will be very costly and only possess sufficient statistical power to detect relatively large excesses in cancers related to asbestos ingestion; and that probably the most pertinent toxicologic experiments relate to resolving the differences in how inhaled asbestos, which is eventually swallowed, is biologically processed by humans, compared to how ingested asbestos is processed. The work group believes that the cancer risk associated with asbestos ingestion should not be perceived as one of the most pressing potential public health hazards facing the nation. However, the work group does not believe that information was sufficient to assess the level of cancer risk associated with the ingestion and therefore, this potential hazard should not be discounted, and ingestion exposure to asbestos should be eliminated whenever possible. PMID:3304998

  2. Vitamin D status and health correlates among apparently healthy participants in an urban, sunny region.

    PubMed

    Vallianou, Natalia; Bountziouka, Vassiliki; Akalestos, Thanasis; Evangelopoulos, Angelos; Vogiatzakis, Evangelos; Bonou, Maria; Barbetseas, John; Avgerinos, Peter C; Panagiotakos, Demosthenes B

    2012-12-01

    To assess vitamin D status and health correlates in a sample of apparently healthy Caucasian participants residing in an urban area, Athens, with latitude 370 58' 0" N and longitude 230 43' 0" E, after taking into consideration a broad range of purported biological, behavioural and environmental factors. Men and women 35+ years from a selected population (n = 490) were studied. Participants completed a detailed questionnaire regarding socio-demographic, lifestyle, clinical and dietary characteristics. Biomarkers were measured after 12 h fasting. Linear and multinomial regression models were used to evaluate the association between 25(OH)D and determinants of vitamin D status. Results revealed that one hour increase of sunlight exposure decreased the odds of having D deficiency (i.e., < 20 ng/mL) by 70% (OR = 0.30, 95% Cl: 0.20-0.45), adjusted for age, sex, family status, physical activity, smoking habits, BMI, triglycerides, parathyroid hormone, uric acid, haptoglobin, folate acid and haemoglobin, as compared to sufficient levels (i.e., >30 ng/mL). Regarding biomarkers, parathyroid hormone and haptoglobin were found to be related with the odds of having vitamin D deficiency (OR = 1.11, 95% CI: 1.05-1.16; OR = 1.02, 95% CI: 1.00-1.03, respectively) as compared to the sufficient levels. Sufficient serum vitamin D levels were observed among participants with characteristics associated with reduced cardiovascular risk, such as normal BMI, increased physical activity, decreased parathyroid hormone and decreased inflammatory markers. Even a slight increase in sunlight exposure could have beneficial effects on serum vitamin D concentrations and eventually on haemoglobin and inflammatory markers levels, thus providing a simple and inexpensive lifestyle intervention that promotes public health.

  3. 24 CFR 984.105 - Minimum program size.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM General § 984.105 Minimum program... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Minimum program size. 984.105 Section 984.105 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  4. 24 CFR 984.204 - On-site facilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Development and Approval Procedures... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false On-site facilities. 984.204 Section 984.204 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued...

  5. 24 CFR 984.202 - Program Coordinating Committee (PCC).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM Program Development and... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Program Coordinating Committee (PCC). 984.202 Section 984.202 Housing and Urban Development Regulations Relating to Housing and Urban...

  6. Asymptotic form for the cross section for the Coulomb interacting rearrangement collisions

    NASA Technical Reports Server (NTRS)

    Omidvar, K.

    1973-01-01

    It is shown that in a rearrangement collision leading to the formation of the highly excited hydrogenlike states the cross section in all orders of the Born approximation behaves as 1/n sq, with n the principal quantum number, thus invalidating the Brinkman-Kramers approximation for large n. Similarly, in high energy inelastic electron-hydrogenlike atom collisions the exchange cross section for sufficiently large n dominates the direct excitation cross section.

  7. Effects of Aging and Environmental Conditions on Ammunition/Explosives Storage Magazines - Paper 1

    DTIC Science & Technology

    2010-07-01

    dropped below 9.5.  Corrosion of the Reinforcing Steel: Steel reinforcement is normally placed within a 2 inches of a concrete surface. Under most...alkalinity of the concrete . The steel is also protected by the relatively high electrical resistance of the concrete . Still, corrosion of the...pressures to force the concrete /reinforcement steel bond to break. Corrosion of the steel will cause spalling, section loss of the steel, and eventually

  8. Environmental Impact Statement for BOMARC Missile Site, McGuire AFB, New Jersey. Volume 1, Sections 1 through 8

    DTIC Science & Technology

    1992-05-22

    laboratory analysis and in-situ survey techniques . It is estimated that the radiological surveys would generate four 55-gallon drums of potentially...the filters would be analyzed daily in the field for alpha activity. If air filter analysis indicates resuspension of plutonium and/or americium...successional change would eventually result in the old field vegetative zone developing into an Oak-Pine community or an oak-hickory climax community

  9. Workstation Segment Specification for the World-Wide Military Command and Control (WWMCCS) Information System (WIS)

    DTIC Science & Technology

    1989-07-01

    software eventually, and which indicate the general thrust of evolution and growth capabilities required of the workstation segment. These GRAY sections...configuration control over the evolution of the system. (" - The transition from the WWMCCS Standard ADP system to WIS will be gradual and will be...has been designed to support the workstation needs required for most WIS users, and is the workstation that will support the long-term evolution of

  10. Experimental investigation of a newly designed supersonic wind tunnel

    NASA Astrophysics Data System (ADS)

    Wu, J.; Radespiel, R.

    2015-06-01

    The flow characteristics of the tandem nozzle supersonic wind tunnel at the Institute of Fluid Mechanics, Technische Universität Braunschweig, a are investigated. Conventional measurement techniques were utilized. The flow development is examined by pressure sensors installed at various streamwise positions. The temperature is measured in the storage tube and the settling chamber. The influence of flow treatment in the settling chamber on the flow quality is also studied. The flow quality of test section is evaluated by a 6-probe Pitot rake. The pressure fluctuations in the test section are studied by a sharp cone model. Eventually, good agreement between the measurements and numerical simulation of the tunnel design is achieved.

  11. Conservative Treatment of a Gossypiboma Causing Uterine Wound Dehiscence

    PubMed Central

    Usta, Taner A.; Ozyurek, Sefik E.; Gundogdu, Elif C.

    2013-01-01

    We present a rare case with gossypiboma following cesarean section which led to uterine wound dehiscence. A 30-year-old woman had been submitted to an emergency cesarean section 4 months previously at another hospital. Clinical and ultrasound findings revealed a large intra-abdominal mass and diffuse peritonitis. At laparotomy, a gossypiboma causing an abscess and uterine wound dehiscence with necrosis of the margins was detected. We performed repetitive wound debridements under broad-spectrum antibiotic cover and eventually resutured the incision. Although hysterectomy has so far been the choice of treatment in the literature once a uterine wound dehiscence had occurred, it was possible in this case to preserve the uterus. PMID:24106624

  12. [Observation of the effects of warming-up and role-playing in psychodrama in terms of mood rating].

    PubMed

    Kawai, S

    1993-04-01

    The purpose is to make an appropriate list of terms that describe person's moment-to-moment changes in moods during psychodrama sessions. Seventy nurse students participated in a series of psychodrama sessions, consisting of a session of warming-up and two sessions of role playing. They rated their moods at the beginning of the sessions and after each session, on a five-point scale for each of the 55 terms, which were supposed to cover all kinds of moods during psychodrama sessions. After analyzing variations (using factor analyses) of subjects' ratings, three factors were found to be sufficient for describing their moods, and the terms in the list were eventually reduced to sixteen. Changes of moods analyzed through the ratings of sixteen scales were related significantly with subjects' performances of warming-up and role playing.

  13. Propagation of partially coherent controllable dark hollow beams with various symmetries in turbulent atmosphere

    NASA Astrophysics Data System (ADS)

    Wang, Haiyan; Li, Xiangyin

    2010-01-01

    Normalized intensity distribution, the complex degree of coherence and power in the bucket for partially coherent controllable dark hollow beams (DHBs) with various symmetries propagating in atmospheric turbulence are derived using tensor method and investigated in detail. Analytical results show that, after sufficient propagation distance, partially coherent DHBs with various symmetries eventually become circular Gaussian beam (without dark hollow) in turbulent atmosphere, which is different from its propagation properties in free space. The partially coherent DHBs return to a circular Gaussian beam rapidly for stronger turbulence, higher coherence, lower beam order, smaller p or smaller beam waist width. Another interesting observation is that the profile of the complex degree of coherence attains a similar profile to that of the average intensity of the related beam propagating in a turbulent atmosphere. Besides the laser power focusablity of DHBs are better than that of Gaussian beam propagating in turbulent atmosphere.

  14. Self-replicating machines in continuous space with virtual physics.

    PubMed

    Smith, Arnold; Turney, Peter; Ewaschuk, Robert

    2003-01-01

    JohnnyVon is an implementation of self-replicating machines in continuous two-dimensional space. Two types of particles drift about in a virtual liquid. The particles are automata with discrete internal states but continuous external relationships. Their internal states are governed by finite state machines, but their external relationships are governed by a simulated physics that includes Brownian motion, viscosity, and springlike attractive and repulsive forces. The particles can be assembled into patterns that can encode arbitrary strings of bits. We demonstrate that, if an arbitrary seed pattern is put in a soup of separate individual particles, the pattern will replicate by assembling the individual particles into copies of itself. We also show that, given sufficient time, a soup of separate individual particles will eventually spontaneously form self-replicating patterns. We discuss the implications of JohnnyVon for research in nanotechnology, theoretical biology, and artificial life.

  15. The computation of the post-stall behavior of a circulation controlled airfoil

    NASA Technical Reports Server (NTRS)

    Linton, Samuel W.

    1993-01-01

    The physics of the circulation controlled airfoil is complex and poorly understood, particularly with regards to jet stall, which is the eventual breakdown of lift augmentation by the jet at some sufficiently high blowing rate. The present paper describes the numerical simulation of stalled and unstalled flows over a two-dimensional circulation controlled airfoil using a fully implicit Navier-Stokes code, and the comparison with experimental results. Mach numbers of 0.3 and 0.5 and jet total to freestream pressure ratios of 1.4 and 1.8 are investigated. The Baldwin-Lomax and k-epsilon turbulence models are used, each modified to include the effect of strong streamline curvature. The numerical solutions of the post-stall circulation controlled airfoil show a highly regular unsteady periodic flowfield. This is the result of an alternation between adverse pressure gradient and shock induced separation of the boundary layer on the airfoil trailing edge.

  16. Science and Technology Directorate Publications and Presentations, January 1-December 31, 2005

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2006-01-01

    This Technical Memorandum (TM) lists the significant publications and presentations of the Science and Technology Directorate during the period January 1-December 31, 2005. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. Questions or requests for additional information about the entries in this report should be directed to Dr. J.F. Spann, Jr. (VP60; 961-7512) or to one of the authors.

  17. Prison Boomers: Policy Implications of Aging Prison Populations

    PubMed Central

    Psick, Zachary; Ahalt, Cyrus; Brown, Rebecca T.; Simon, Jonathan

    2018-01-01

    Prison populations worldwide are aging at an unprecedented rate, and associated age-related medical costs have had serious consequences for jurisdictions struggling to respond to the changes. Our examination of the situation in California shows that recognizing the changing healthcare needs of aging prison populations is critical to achieving effective and efficient policies and practices that affect this medically vulnerable and costly population. Chronic prison overcrowding usually accompanies the aging trends, and there is evidence that aging is strongly correlated with desistance from criminal behavior, suggesting an opportunity to at least partially address the challenges through early release of appropriate persons. Some relevant policies do exist, but they have not achieved this goal on a sufficient scale. Drawing lessons from California and available scholarship, we conclude with recommendations for those faced with responding to the unprecedented number of older adults now in prison, most of whom will eventually be released. PMID:28299972

  18. Biotechnology software in the digital age: are you winning?

    PubMed

    Scheitz, Cornelia Johanna Franziska; Peck, Lawrence J; Groban, Eli S

    2018-01-16

    There is a digital revolution taking place and biotechnology companies are slow to adapt. Many pharmaceutical, biotechnology, and industrial bio-production companies believe that software must be developed and maintained in-house and that data are more secure on internal servers than on the cloud. In fact, most companies in this space continue to employ large IT and software teams and acquire computational infrastructure in the form of in-house servers. This is due to a fear of the cloud not sufficiently protecting in-house resources and the belief that their software is valuable IP. Over the next decade, the ability to quickly adapt to changing market conditions, with agile software teams, will quickly become a compelling competitive advantage. Biotechnology companies that do not adopt the new regime may lose on key business metrics such as return on invested capital, revenue, profitability, and eventually market share.

  19. Chemotaxis with logistic source

    NASA Astrophysics Data System (ADS)

    Winkler, Michael

    2008-12-01

    We consider the chemotaxis system in a smooth bounded domain , where [chi]>0 and g generalizes the logistic function g(u)=Au-bu[alpha] with [alpha]>1, A[greater-or-equal, slanted]0 and b>0. A concept of very weak solutions is introduced, and global existence of such solutions for any nonnegative initial data u0[set membership, variant]L1([Omega]) is proved under the assumption that . Moreover, boundedness properties of the constructed solutions are studied. Inter alia, it is shown that if b is sufficiently large and u0[set membership, variant]L[infinity]([Omega]) has small norm in L[gamma]([Omega]) for some then the solution is globally bounded. Finally, in the case that additionally holds, a bounded set in L[infinity]([Omega]) can be found which eventually attracts very weak solutions emanating from arbitrary L1 initial data. The paper closes with numerical experiments that illustrate some of the theoretically established results.

  20. Controlling nitrogen migration through micro-nano networks

    NASA Astrophysics Data System (ADS)

    Cai, Dongqing; Wu, Zhengyan; Jiang, Jiang; Wu, Yuejin; Feng, Huiyun; Brown, Ian G.; Chu, Paul K.; Yu, Zengliang

    2014-01-01

    Nitrogen fertilizer unabsorbed by crops eventually discharges into the environment through runoff, leaching and volatilization, resulting in three-dimensional (3D) pollution spanning from underground into space. Here we describe an approach for controlling nitrogen loss, developed using loss control fertilizer (LCF) prepared by adding modified natural nanoclay (attapulgite) to traditional fertilizer. In the aqueous phase, LCF self-assembles to form 3D micro/nano networks via hydrogen bonds and other weak interactions, obtaining a higher nitrogen spatial scale so that it is retained by a soil filtering layer. Thus nitrogen loss is reduced and sufficient nutrition for crops is supplied, while the pollution risk of the fertilizer is substantially lowered. As such, self-fabrication of nano-material was used to manipulate the nitrogen spatial scale, which provides a novel and promising approach for the research and control of the migration of other micro-scaled pollutants in environmental medium.

  1. Space Sciences Laboratory Publications and Presentations: January 1 - December 31,1998

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    1999-01-01

    This document lists the significant publications and presentations of the Space Sciences Laboratory during the period January 1 - December 31, 1998. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. Questions or requests for additional information about the entries in this report should be directed to Gregory S. Wilson (ES01; 544-7579) or to one of the authors. The organizational code of the cognizant SSL branch or office is given at the end of each entry.

  2. Cytosolic Irradiation of Femtosecond Laser Induces Mitochondria-dependent Apoptosis-like Cell Death via Intrinsic Reactive Oxygen Cascades

    PubMed Central

    Yoon, Jonghee; Ryu, Seung-wook; Lee, Seunghee; Choi, Chulhee

    2015-01-01

    High-intensity femtosecond lasers have recently been used to irreversibly disrupt nanoscale structures, such as intracellular organelles, and to modify biological functions in a reversible manner: so-called nanosurgery and biophotomodulation. Femtosecond laser pulses above the threshold intensity sufficient for reversible biophotomodulation can cause irreversible changes in the irradiated cell, eventually leading to cell death. Here, we demonstrated that cytosolic irradiation with a femtosecond laser produced intrinsic cascades of reactive oxygen species (ROS), which led to rapid apoptosis-like cell death via a caspase and poly (ADP-ribose) polymerase 1 (PARP-1) signaling pathway. We further showed that cells with enhanced mitochondrial fusion activity are more resilient to laser-induced stress compared to those with enforced mitochondrial fission. Taken together, these findings provide fundamental insight into how optical stimulation intervenes in intrinsic cellular signaling pathways and functions. PMID:25648455

  3. Cytosolic irradiation of femtosecond laser induces mitochondria-dependent apoptosis-like cell death via intrinsic reactive oxygen cascades.

    PubMed

    Yoon, Jonghee; Ryu, Seung-Wook; Lee, Seunghee; Choi, Chulhee

    2015-02-04

    High-intensity femtosecond lasers have recently been used to irreversibly disrupt nanoscale structures, such as intracellular organelles, and to modify biological functions in a reversible manner: so-called nanosurgery and biophotomodulation. Femtosecond laser pulses above the threshold intensity sufficient for reversible biophotomodulation can cause irreversible changes in the irradiated cell, eventually leading to cell death. Here, we demonstrated that cytosolic irradiation with a femtosecond laser produced intrinsic cascades of reactive oxygen species (ROS), which led to rapid apoptosis-like cell death via a caspase and poly (ADP-ribose) polymerase 1 (PARP-1) signaling pathway. We further showed that cells with enhanced mitochondrial fusion activity are more resilient to laser-induced stress compared to those with enforced mitochondrial fission. Taken together, these findings provide fundamental insight into how optical stimulation intervenes in intrinsic cellular signaling pathways and functions.

  4. Controlling nitrogen migration through micro-nano networks.

    PubMed

    Cai, Dongqing; Wu, Zhengyan; Jiang, Jiang; Wu, Yuejin; Feng, Huiyun; Brown, Ian G; Chu, Paul K; Yu, Zengliang

    2014-01-14

    Nitrogen fertilizer unabsorbed by crops eventually discharges into the environment through runoff, leaching and volatilization, resulting in three-dimensional (3D) pollution spanning from underground into space. Here we describe an approach for controlling nitrogen loss, developed using loss control fertilizer (LCF) prepared by adding modified natural nanoclay (attapulgite) to traditional fertilizer. In the aqueous phase, LCF self-assembles to form 3D micro/nano networks via hydrogen bonds and other weak interactions, obtaining a higher nitrogen spatial scale so that it is retained by a soil filtering layer. Thus nitrogen loss is reduced and sufficient nutrition for crops is supplied, while the pollution risk of the fertilizer is substantially lowered. As such, self-fabrication of nano-material was used to manipulate the nitrogen spatial scale, which provides a novel and promising approach for the research and control of the migration of other micro-scaled pollutants in environmental medium.

  5. Charge loss (or the lack thereof) for AdS black holes

    NASA Astrophysics Data System (ADS)

    Ong, Yen Chin; Chen, Pisin

    2014-06-01

    The evolution of evaporating charged black holes is complicated to model in general, but is nevertheless important since the hints to the Information Loss Paradox and its recent firewall incarnation may lie in understanding more generic geometries than that of Schwarzschild spacetime. Fortunately, for sufficiently large asymptotically flat Reissner-Nordström black holes, the evaporation process can be modeled via a system of coupled linear ordinary differential equations, with charge loss rate governed by Schwinger pair-production process. The same model can be generalized to study the evaporation of AdS Reissner-Nordström black holes with flat horizon. It was recently found that such black holes always evolve towards extremality since charge loss is inefficient. This property is completely opposite to the asymptotically flat case in which the black hole eventually loses its charges and tends towards Schwarzschild limit. We clarify the underlying reason for this different behavior.

  6. Welsh settlement patterns in a nineteenth-century Australian gold town.

    PubMed

    Tyler, Robert

    2009-01-01

    The adjacent gold mining settlements of Ballarat and Sebastopol in the colony of Victoria are universally acknowledged as the major focal point for Welsh immigrants in Australia in the second half of the nineteenth century. Here, the Welsh had congregated in sufficient numbers to establish an identifiable and highly visible ethnolinguistic community. Factors such as the necessity of acquiring the English language, movement out of the mining industry, high rates of exogamy, the failure to unite within one religious denomination and the conscious desire to integrate into mainstream Australian society, all served to undermine the integrity of that community. This paper argues that the more fundamental issue of residential propinquity was of primary importance in this process; that it was the failure of the Welsh immigrant group to establish and maintain long term exclusively Welsh areas of settlement that ensured the eventual dilution and absorption of the Welsh as a distinct community.

  7. Seismogenic width controls aspect ratios of earthquake ruptures

    NASA Astrophysics Data System (ADS)

    Weng, Huihui; Yang, Hongfeng

    2017-03-01

    We investigate the effect of seismogenic width on aspect ratios of earthquake ruptures by using numerical simulations of strike-slip faulting and an energy balance criterion near rupture tips. If the seismogenic width is smaller than a critical value, then ruptures cannot break the entire fault, regardless of the size of the nucleation zone. The seismic moments of these self-arresting ruptures increase with the nucleation size, forming nucleation-related events. The aspect ratios increase with the seismogenic width but are smaller than 8. In contrast, ruptures become breakaway and tend to have high aspect ratios (>8) if the seismogenic width is sufficiently large. But the critical nucleation size is larger than the theoretical estimate for an unbounded fault. The eventual seismic moments of breakaway ruptures do not depend on the nucleation size. Our results suggest that estimating final earthquake magnitude from the nucleation phase may only be plausible on faults with small seismogenic width.

  8. The rise and fall of a human recombination hot spot.

    PubMed

    Jeffreys, Alec J; Neumann, Rita

    2009-05-01

    Human meiotic crossovers mainly cluster into narrow hot spots that profoundly influence patterns of haplotype diversity and that may also affect genome instability and sequence evolution. Hot spots also seem to be ephemeral, but processes of hot-spot activation and their subsequent evolutionary dynamics remain unknown. We now analyze the life cycle of a recombination hot spot. Sperm typing revealed a polymorphic hot spot that was activated in cis by a single base change, providing evidence for a primary sequence determinant necessary, though not sufficient, to activate recombination. This activating mutation occurred roughly 70,000 y ago and has persisted to the present, most likely fortuitously through genetic drift despite its systematic elimination by biased gene conversion. Nonetheless, this self-destructive conversion will eventually lead to hot-spot extinction. These findings define a subclass of highly transient hot spots and highlight the importance of understanding hot-spot turnover and how it influences haplotype diversity.

  9. High-speed photogrammetry system for measuring the kinematics of insect wings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wallace, Iain D.; Lawson, Nicholas J.; Harvey, Andrew R.

    2006-06-10

    We describe and characterize an experimental system to perform shape measurements on deformable objects using high-speed close-range photogrammetry. The eventual application is to extract the kinematics of several marked points on an insect wing during tethered and hovering flight. We investigate the performance of the system with a small number of views and determine an empirical relation between the mean pixel error of the optimization routine and the position error. Velocity and acceleration are calculated by numerical differencing, and their relation to the position errors is verified. For a field of view of {approx}40mmx40 mm, a rms accuracy of 30more » {mu}m in position, 150 mm/s in velocity, and 750 m/s2 in acceleration at 5000 frames/s is achieved. This accuracy is sufficient to measure the kinematics of hoverfly flight.« less

  10. Science and Technology Directorate Publications and Presentations, January 1-December 31, 2004

    NASA Technical Reports Server (NTRS)

    Summers, F. G. (Compiler)

    2005-01-01

    This Technical Memorandum (TM) lists the significant publications and presentations of the Science and Technology Directorate during the period January 1-December 31, 2004. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. Questions or requests for additional information about the entries in this report should be directed to Dr. A.F. Whitaker (SD01; 544 2481) or to one of the authors.

  11. Controlling nitrogen migration through micro-nano networks

    PubMed Central

    Cai, Dongqing; Wu, Zhengyan; Jiang, Jiang; Wu, Yuejin; Feng, Huiyun; Brown, Ian G.; Chu, Paul K.; Yu, Zengliang

    2014-01-01

    Nitrogen fertilizer unabsorbed by crops eventually discharges into the environment through runoff, leaching and volatilization, resulting in three-dimensional (3D) pollution spanning from underground into space. Here we describe an approach for controlling nitrogen loss, developed using loss control fertilizer (LCF) prepared by adding modified natural nanoclay (attapulgite) to traditional fertilizer. In the aqueous phase, LCF self-assembles to form 3D micro/nano networks via hydrogen bonds and other weak interactions, obtaining a higher nitrogen spatial scale so that it is retained by a soil filtering layer. Thus nitrogen loss is reduced and sufficient nutrition for crops is supplied, while the pollution risk of the fertilizer is substantially lowered. As such, self-fabrication of nano-material was used to manipulate the nitrogen spatial scale, which provides a novel and promising approach for the research and control of the migration of other micro-scaled pollutants in environmental medium. PMID:24419037

  12. INEEL Subregional Conceptual Model Report Volume 2: Summary of Existing Knowledge of Geochemical Influences on the Fate and Transport of Contaminants in the Subsurface at the INEEL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paul L. Wichlacz; Robert C. Starr; Brennon Orr

    2003-09-01

    This document summarizes previous descriptions of geochemical system conceptual models for the vadose zone and groundwater zone (aquifer) beneath the Idaho National Engineering and Environmental Laboratory (INEEL). The primary focus is on groundwater because contaminants derived from wastes disposed at INEEL are present in groundwater, groundwater provides a pathway for potential migration to receptors, and because geochemical characteristics in and processes in the aquifer can substantially affect the movement, attenuation, and toxicity of contaminants. The secondary emphasis is perched water bodies in the vadose zone. Perched water eventually reaches the regional groundwater system, and thus processes that affect contaminants inmore » the perched water bodies are important relative to the migration of contaminants into groundwater. Similarly, processes that affect solutes during transport from nearsurface disposal facilities downward through the vadose zone to the aquifer are relevant. Sediments in the vadose zone can affect both water and solute transport by restricting the downward migration of water sufficiently that a perched water body forms, and by retarding solute migration via ion exchange. Geochemical conceptual models have been prepared by a variety of researchers for different purposes. They have been published in documents prepared by INEEL contractors, the United States Geological Survey (USGS), academic researchers, and others. The documents themselves are INEEL and USGS reports, and articles in technical journals. The documents reviewed were selected from citation lists generated by searching the INEEL Technical Library, the INEEL Environmental Restoration Optical Imaging System, and the ISI Web of Science databases. The citation lists were generated using the keywords ground water, groundwater, chemistry, geochemistry, contaminant, INEL, INEEL, and Idaho. In addition, a list of USGS documents that pertain to the INEEL was obtained and manually searched. The documents that appeared to be the most pertinent were selected from further review. These documents are tabulated in the citation list. This report summarizes existing geochemical conceptual models, but does not attempt to generate a new conceptual model or select the ''right'' model. This document is organized as follows. Geochemical models are described in general in Section 2. Geochemical processes that control the transport and fate of contaminants introduced into groundwater are described in Section 3. The natural geochemistry of the Eastern Snake River Plain Aquifer (SRPA) is described in Section 4. The effect of waste disposal on the INEEL subsurface is described in Section 5. The geochemical behavior of the major contaminants is described in Section 6. Section 7 describes the site-specific geochemical models developed for various INEEL facilities.« less

  13. Toward Self Sufficiency: Social Issues in the Nineties. Proceedings of the National Association for Welfare Research and Statistics (33rd, Scottsdale, Arizona, August 7-11, 1993).

    ERIC Educational Resources Information Center

    National Association for Welfare Research and Statistics, Olympia, WA.

    The presentations compiled in these proceedings on welfare and self-sufficiency reflect much of the current research in areas of housing, health, employment and training, welfare and reform, nutrition, child support, child care, and youth. The first section provides information on the conference and on the National Association for Welfare Research…

  14. 21 CFR 133.148 - Hard grating cheeses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... purposes of this section, the word “milk” means cow's milk or goat's milk or sheep's milk or mixtures of... of sheep's milk) the corresponding products from sheep's milk; water in a quantity sufficient to... milk and the other ingredients specified in this section, by the procedure set forth in paragraph (b...

  15. 21 CFR 133.148 - Hard grating cheeses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... purposes of this section, the word “milk” means cow's milk or goat's milk or sheep's milk or mixtures of... of sheep's milk) the corresponding products from sheep's milk; water in a quantity sufficient to... milk and the other ingredients specified in this section, by the procedure set forth in paragraph (b...

  16. 21 CFR 133.148 - Hard grating cheeses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... purposes of this section, the word “milk” means cow's milk or goat's milk or sheep's milk or mixtures of... of sheep's milk) the corresponding products from sheep's milk; water in a quantity sufficient to... milk and the other ingredients specified in this section, by the procedure set forth in paragraph (b...

  17. 24 CFR 984.101 - Purpose, scope, and applicability.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM General § 984.101 Purpose... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Purpose, scope, and applicability. 984.101 Section 984.101 Housing and Urban Development Regulations Relating to Housing and Urban...

  18. Computer-Aided Instruction.

    ERIC Educational Resources Information Center

    Hunt, Graham

    This report discusses the impact of and presents guidelines for developing a computer-aided instructional (CAI) system. The first section discusses CAI in terms of the need for the countries of Asia to increase their economic self-sufficiency. The second section examines various theories on the nature of learning with special attention to the role…

  19. 24 CFR 964.7 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contract to manage one or more management activities of a HA. Resident-owned business. Any business concern.... If the HA is combining FIC with the Family Self-Sufficiency (FSS) program, the term also means Public Housing FSS and Section 8 families participating in the FSS program. Although Section 8 FSS families are...

  20. Non-Ligand-Induced Dimerization is Sufficient to Initiate the Signalling and Endocytosis of EGF Receptor.

    PubMed

    Kourouniotis, George; Wang, Yi; Pennock, Steven; Chen, Xinmei; Wang, Zhixiang

    2016-07-25

    The binding of epidermal growth factor (EGF) to EGF receptor (EGFR) stimulates cell mitogenesis and survival through various signalling cascades. EGF also stimulates rapid EGFR endocytosis and its eventual degradation in lysosomes. The immediate events induced by ligand binding include receptor dimerization, activation of intrinsic tyrosine kinase and autophosphorylation. However, in spite of intensified efforts, the results regarding the roles of these events in EGFR signalling and internalization is still very controversial. In this study, we constructed a chimeric EGFR by replacing its extracellular domain with leucine zipper (LZ) and tagged a green fluorescent protein (GFP) at its C-terminus. We showed that the chimeric LZ-EGFR-GFP was constitutively dimerized. The LZ-EGFR-GFP dimer autophosphorylated each of its five well-defined C-terminal tyrosine residues as the ligand-induced EGFR dimer does. Phosphorylated LZ-EGFR-GFP was localized to both the plasma membrane and endosomes, suggesting it is capable of endocytosis. We also showed that LZ-EGFR-GFP activated major signalling proteins including Src homology collagen-like (Shc), extracellular signal-regulated kinase (ERK) and Akt. Moreover, LZ-EGFR-GFP was able to stimulate cell proliferation. These results indicate that non-ligand induced dimerization is sufficient to activate EGFR and initiate cell signalling and EGFR endocytosis. We conclude that receptor dimerization is a critical event in EGF-induced cell signalling and EGFR endocytosis.

  1. Annual modulation of seismicity along the San Andreas Fault near Parkfield, CA

    USGS Publications Warehouse

    Christiansen, L.B.; Hurwitz, S.; Ingebritsen, S.E.

    2007-01-01

    We analyze seismic data from the San Andreas Fault (SAF) near Parkfield, California, to test for annual modulation in seismicity rates. We use statistical analyses to show that seismicity is modulated with an annual period in the creeping section of the fault and a semiannual period in the locked section of the fault. Although the exact mechanism for seasonal triggering is undetermined, it appears that stresses associated with the hydrologic cycle are sufficient to fracture critically stressed rocks either through pore-pressure diffusion or crustal loading/ unloading. These results shed additional light on the state of stress along the SAF, indicating that hydrologically induced stress perturbations of ???2 kPa may be sufficient to trigger earthquakes.

  2. Polycyanurate Networks with Enhanced Segmental Flexibility and Outstanding Thermochemical Stability (Pre-Print)

    DTIC Science & Technology

    2013-01-01

    anhydrous MgSO4, the solvent was rotary evaporated leaving a pale yellow oil that eventually solidified under vacuum . Recrystallization of the...colorless oil . Reduced pressure (0.1 torr) distillation gave the title compound in analytically pure form. The yield was 3.87 g (41 %). 1H NMR (300 MHz...in Supporting Information Section S5). The Tg values were similar after 24 hours of cure at 210 °C under a nitrogen atmosphere with no added

  3. Criteria for evaluation of reflective surface for parabolic dish concentrators

    NASA Technical Reports Server (NTRS)

    Bouquet, F.

    1980-01-01

    Commercial, second surface glass mirror are emphasized, but aluminum and metallized polymeric films are also included. Criteria for sealing solar mirrors in order to prevent environmental degradation and criteria for bonding sagged or bent mirrors to substrate materials are described. An overview of the technical areas involved in evaluating small mirror samples, sections, and entire large gores is presented. A basis for mirror criteria was established that eventually may become part of inspection and evaluation techniques for three dimensional parabolic reflective surfaces.

  4. Feasibility of using tissue microarray cores of paraffin-embedded breast cancer tissue for measurement of gene expression: a proof-of-concept study.

    PubMed

    Drury, Suzanne; Salter, Janine; Baehner, Frederick L; Shak, Steven; Dowsett, Mitch

    2010-06-01

    To determine whether 0.6 mm cores of formalin-fixed paraffin-embedded (FFPE) tissue, as commonly used to construct immunohistochemical tissue microarrays, may be a valid alternative to tissue sections as source material for quantitative real-time PCR-based transcriptional profiling of breast cancer. Four matched 0.6 mm cores of invasive breast tumour and two 10 microm whole sections were taken from eight FFPE blocks. RNA was extracted and reverse transcribed, and TaqMan assays were performed on the 21 genes of the Oncotype DX Breast Cancer assay. Expression of the 16 recurrence-related genes was normalised to the set of five reference genes, and the recurrence score (RS) was calculated. RNA yield was lower from 0.6 mm cores than from 10 microm whole sections, but was still more than sufficient to perform the assay. RS and single gene data from cores were highly comparable with those from whole sections (RS p=0.005). Greater variability was seen between cores than between sections. FFPE sections are preferable to 0.6 mm cores for RNA profiling in order to maximise RNA yield and to allow for standard histopathological assessment. However, 0.6 mm cores are sufficient and would be appropriate to use for large cohort studies.

  5. 24 CFR 984.304 - Total tenant payment, family rent, and increases in family income.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Total tenant payment, family rent, and increases in family income. 984.304 Section 984.304 Housing and Urban Development REGULATIONS... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY...

  6. 78 FR 11644 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... Region 6, Water Quality Protection Division. The Applicant has provided sufficient documentation to... INFORMATION CONTACT: Nasim Jahan, Buy American Coordinator, (214) 665-7522, SRF & Projects Section, Water... and overcome the high shear stress found in a stream environment. Additional key requirements of the...

  7. 24 CFR 984.104 - Basic requirements of the FSS program.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY PROGRAM General § 984.104 Basic... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Basic requirements of the FSS program. 984.104 Section 984.104 Housing and Urban Development Regulations Relating to Housing and Urban...

  8. 26 CFR 31.3401(a)(15)-1 - Moving expenses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 15 2012-04-01 2012-04-01 false Moving expenses. 31.3401(a)(15)-1 Section 31... corresponding deduction is or will be allowable to the employee under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even...

  9. 26 CFR 31.3121(a)(11)-1 - Moving expenses.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 15 2012-04-01 2012-04-01 false Moving expenses. 31.3121(a)(11)-1 Section 31... under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even though such evidence may be insufficient upon closer...

  10. 26 CFR 31.3401(a)(15)-1 - Moving expenses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Moving expenses. 31.3401(a)(15)-1 Section 31... corresponding deduction is or will be allowable to the employee under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even...

  11. 26 CFR 31.3401(a)(15)-1 - Moving expenses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 15 2013-04-01 2013-04-01 false Moving expenses. 31.3401(a)(15)-1 Section 31... corresponding deduction is or will be allowable to the employee under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even...

  12. 26 CFR 31.3401(a)(15)-1 - Moving expenses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Moving expenses. 31.3401(a)(15)-1 Section 31... corresponding deduction is or will be allowable to the employee under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even...

  13. 26 CFR 31.3121(a)(11)-1 - Moving expenses.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Moving expenses. 31.3121(a)(11)-1 Section 31... under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even though such evidence may be insufficient upon closer...

  14. 26 CFR 31.3121(a)(11)-1 - Moving expenses.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 15 2013-04-01 2013-04-01 false Moving expenses. 31.3121(a)(11)-1 Section 31... under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even though such evidence may be insufficient upon closer...

  15. 26 CFR 31.3121(a)(11)-1 - Moving expenses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 15 2014-04-01 2014-04-01 false Moving expenses. 31.3121(a)(11)-1 Section 31... under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even though such evidence may be insufficient upon closer...

  16. 26 CFR 31.3401(a)(15)-1 - Moving expenses.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 15 2014-04-01 2014-04-01 false Moving expenses. 31.3401(a)(15)-1 Section 31... corresponding deduction is or will be allowable to the employee under section 217. The reasonable belief contemplated by the statute may be based upon any evidence reasonably sufficient to induce such belief, even...

  17. 49 CFR 38.23 - Mobility aid accessibility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....g., lift or ramp) complying with paragraph (b) or (c) of this section and sufficient clearances to... this section, shall be provided on vehicles 22 feet in length or less. (b) Vehicle lift—(1) Design load. The design load of the lift shall be at least 600 pounds. Working parts, such as cables, pulleys, and...

  18. 49 CFR 38.23 - Mobility aid accessibility.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....g., lift or ramp) complying with paragraph (b) or (c) of this section and sufficient clearances to... this section, shall be provided on vehicles 22 feet in length or less. (b) Vehicle lift—(1) Design load. The design load of the lift shall be at least 600 pounds. Working parts, such as cables, pulleys, and...

  19. 26 CFR 20.2053-9 - Deduction for certain State death taxes.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... citizens), but only if (1) the conditions stated in paragraph (b) of this section are met, and (2) an... which section 2058 is applicable. (b) Condition for allowance of deduction. (1) The deduction is not... decedent's gross estate. For allowance of the credit, it is sufficient if either of these conditions is...

  20. 24 CFR 984.304 - Total tenant payment, family rent, and increases in family income.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Total tenant payment, family rent, and increases in family income. 984.304 Section 984.304 Housing and Urban Development Regulations... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 AND PUBLIC HOUSING FAMILY SELF-SUFFICIENCY...

  1. 40 CFR 149.109 - Decision under section 1424(e).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) SOLE SOURCE AQUIFERS Review of Projects Affecting the Edwards Underground Reservoir, A Designated Sole Source Aquifer in the San Antonio, Texas Area § 149.109 Decision under section 1424(e). (a... hazard to public health is not sufficiently great so as to prevent commitment of Federal funding to the...

  2. The Importance of Physical Fitness versus Physical Activity for Coronary Artery Disease Risk Factors: A Cross-Sectional Analysis.

    ERIC Educational Resources Information Center

    Young, Deborah Rohm; Steinhardt, Mary A.

    1993-01-01

    This cross-sectional study examined relationships among physical fitness, physical activity, and risk factors for coronary artery disease (CAD) in male police officers. Data from screenings and physical fitness assessments indicated physical activity must be sufficient to influence fitness before obtaining statistically significant risk-reducing…

  3. 77 FR 48858 - Significant New Use Rules on Certain Chemical Substances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... affect certain entities through pre-existing import certification and export notification rules under... developing test data. B. What is the agency's authority for taking this action? Section 5(a)(2) of TSCA (15 U....e., SNURs without TSCA section 5(e) consent orders). Tests recommended by EPA to provide sufficient...

  4. Ion track etching revisited: II. Electronic properties of aged tracks in polymers

    NASA Astrophysics Data System (ADS)

    Fink, D.; Muñoz Hernández, G.; Cruz, S. A.; Garcia-Arellano, H.; Vacik, J.; Hnatowicz, V.; Kiv, A.; Alfonta, L.

    2018-02-01

    We compile here electronic ion track etching effects, such as capacitive-type currents, current spike emission, phase shift, rectification and background currents that eventually emerge upon application of sinusoidal alternating voltages across thin, aged swift heavy ion-irradiated polymer foils during etching. Both capacitive-type currents and current spike emission occur as long as obstacles still prevent a smooth continuous charge carrier passage across the foils. In the case of sufficiently high applied electric fields, these obstacles are overcome by spike emission. These effects vanish upon etchant breakthrough. Subsequent transmitted currents are usually of Ohmic type, but shortly after breakthrough (during the track' core etching) often still exhibit deviations such as strong positive phase shifts. They stem from very slow charge carrier mobility across the etched ion tracks due to retarding trapping/detrapping processes. Upon etching the track's penumbra, one occasionally observes a split-up into two transmitted current components, one with positive and another one with negative phase shifts. Usually, these phase shifts vanish when bulk etching starts. Current rectification upon track etching is a very frequent phenomenon. Rectification uses to inverse when core etching ends and penumbra etching begins. When the latter ends, rectification largely vanishes. Occasionally, some residual rectification remains which we attribute to the aged polymeric bulk itself. Last not least, we still consider background currents which often emerge transiently during track etching. We could assign them clearly to differences in the electrochemical potential of the liquids on both sides of the etched polymer foils. Transient relaxation effects during the track etching cause their eventually chaotic behaviour.

  5. A model of excitation and adaptation in bacterial chemotaxis.

    PubMed Central

    Hauri, D C; Ross, J

    1995-01-01

    We present a model of the chemotactic mechanism of Escherichia coli that exhibits both initial excitation and eventual complete adaptation to any and all levels of stimulus ("exact" adaptation). In setting up the reaction network, we use only known interactions and experimentally determined cytosolic concentrations. Whenever possible, rate coefficients are first assigned experimentally measured values; second, we permit some variation in these rate coefficients by using a multiple-well optimization technique and incremental adjustment to obtain values that are sufficient to engender initial response to stimuli (excitation) and an eventual return of behavior to baseline (adaptation). The predictions of the model are similar to the observed behavior of wild-type bacteria in regard to the time scale of excitation in the presence of both attractant and repellent. The model predicts a weaker response to attractant than that observed experimentally, and the time scale of adaptation does not depend as strongly upon stimulant concentration as does that for wild-type bacteria. The mechanism responsible for long-term adaptation is local rather than global: on addition of a repellent or attractant, the receptor types not sensitive to that attractant or repellent do not change their average methylation level in the long term, although transient changes do occur. By carrying out a phenomenological simulation of bacterial chemotaxis, we find that the model is insufficiently sensitive to effect taxis in a gradient of attractant. However, by arbitrarily increasing the sensitivity of the motor to the tumble effector (phosphorylated CheY), we can obtain chemotactic behavior. Images FIGURE 6 FIGURE 7 PMID:7696522

  6. Two waves of anisotropic growth generate enlarged follicles in the spiny mouse

    PubMed Central

    2014-01-01

    Background Mammals exhibit a remarkable variety of phenotypes and comparative studies using novel model species are needed to uncover the evolutionary developmental mechanisms generating this diversity. Here, we undertake a developmental biology and numerical modeling approach to investigate the development of skin appendages in the spiny mouse, Acomys dimidiatus. Results We demonstrate that Acomys spines, possibly involved in display and protection, are enlarged awl hairs with a concave morphology. The Acomys spines originate from enlarged placodes that are characterized by a rapid downwards growth which results in voluminous follicles. The dermal condensation (dermal papilla) at the core of the follicle is very large and exhibits a curved geometry. Given its off-centered position, the dermal papilla generates two waves of anisotropic proliferation, first of the posterior matrix, then of the anterior inner root sheath (IRS). Higher in the follicle, the posterior and anterior cortex cross-section areas substantially decrease due to cortex cell elongation and accumulation of keratin intermediate filaments. Milder keratinization in the medulla gives rise to a foamy material that eventually collapses under the combined compression of the anterior IRS and elongation of the cortex cells. Simulations, using linear elasticity theory and the finite-element method, indicate that these processes are sufficient to replicate the time evolution of the Acomys spine layers and the final shape of the emerging spine shaft. Conclusions Our analyses reveal how hair follicle morphogenesis has been altered during the evolution of the Acomys lineage, resulting in a shift from ancestral awl follicles to enlarged asymmetrical spines. This study contributes to a better understanding of the evolutionary developmental mechanisms that generated the great diversity of skin appendage phenotypes observed in mammals. PMID:25705371

  7. Characterization, degradation, and mechanical strength of poly(D,L-lactide-co-epsilon-caprolactone)-poly(ethylene glycol)-poly(D,L-lactide-co-epsilon-caprolactone).

    PubMed

    Bramfeldt, Hanna; Sarazin, Pierre; Vermette, Patrick

    2007-11-01

    A series of three biocompatible P(CL-co-LA)-PEG-P(CL-co-LA) copolymers were synthesized using ring-opening polymerization and characterized by 1H-NMR, gel permeation chromatography, DSC, dynamic-mechanical analysis, and X-ray diffraction. The number of monomer units was kept constant, while the D,L-LA fraction was varied so as to constitute 0, 30, or 70% of the end segments. The molecular weights were sufficiently high to eventually permit 3D scaffold preparation. A degradation study was carried out over 26 weeks, and the effect of monomer composition on the rate of degradation as well as on changes in mechanical strength was investigated. Pure polycaprolactone (PCL)-poly(ethylene glycol) (PEG)-PCL copolymer, P(100/0), was a crystalline material displaying no measurable mass loss, a 30% reduction in mean molecular weight (Mn), and only very slight changes in tensile strength. The random incorporation of 30 and 70% D,L-LA into the end sections of the polymer chain, produced more and more amorphous materials, exhibiting increasingly high rates of degradation, mass loss, and loss of tensile strength. Compared with random P(CL-co-LA), the presence of the PEG block was found both to improve hydrophilicity and thus the rate of degradation and to infer a stabilizing quality, thereby pacing the decrease in tensile strength during degradation. The tested copolymers range from materials exhibiting low mechanical strength and high rate of degradation to slow-degrading materials with high mechanical strength suitable, e.g., for three-dimensional scaffolding. Copyright (c) 2007 Wiley Periodicals, Inc.

  8. CdSe/CdS semiconductor quantum rods as robust fluorescent probes for paraffin-embedded tissue imaging.

    PubMed

    Zacheo, Antonella; Quarta, Alessandra; Mangoni, Antonella; Pompa, Pier Paolo; Mastria, Rosanna; Capogrossi, Maurizio C; Rinaldi, Ross; Pellegrino, Teresa

    2011-09-01

    Immunofluorescence techniques on formalin fixed paraffin-embedded sections allow for the evaluation of the expression and spatial distribution of specific markers in patient tissue specimens or for monitoring the fate of labeled cells after in vivo injection. This technique suffers however from the auto-fluorescence background signal of the embedded tissue that eventually confounds the analysis. Here we show that rod-like semiconductor nanocrystals (QRs), intramuscularly injected in living mice, could be clearly detected by confocal microscopy in formalin fixed paraffin-embedded tissue sections. Despite the low amount of QRs amount injected (25 picomoles), these were clearly visible after 24 h in the muscle sections and their fluorescence signal was stronger than that of CdSe/ZnS quantum dots (QDs) similarly functionalized and in the case of QRs only, the signal lasted even after 21 days after the injection. © 2011 IEEE

  9. 40 CFR 88.306-94 - Requirements for a converted vehicle to qualify as a clean-fuel fleet vehicle.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... exemption from the post-installation emission test requirements of paragraph (c) of this section. If granted...) Sufficient information to demonstrate that complying with the post-installation emission test requirement... are subject to the post-installation test requirement of paragraph (c)(2) of this section. (iii) If...

  10. 76 FR 18757 - Notice of a Project Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... that there are currently no domestic manufactured wind turbines available in sufficient and reasonable... exception to Section 1605(a) of ARRA. This action permits the purchase of foreign manufactured wind turbine... purchase of a Leitwind LTW 77 wind turbine generator, manufactured by Leitner-Poma, that meets the...

  11. Student Success Rate in Online Learning Support Classes Compared to Traditional Classes

    ERIC Educational Resources Information Center

    Pope, Holly

    2013-01-01

    West Georgia Technical College (WGTC) did not offer online learning support courses and was losing students to other colleges that offered those courses online. Adding to this problem, online learning support class sections were not being added without sufficient proof that students could receive the same level of education in an online section as…

  12. 26 CFR 1.964-3 - Records to be provided by United States shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... books of account or records as are sufficient to satisfy the requirements of section 6001 and section 964(c), or true copies thereof, as are reasonably demanded, and (2) If such books or records are not maintained in the English language, either (i) an accurate English translation of such books or records or...

  13. 40 CFR 86.1864-10 - How to comply with the fleet average cold temperature NMHC standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., manufacturers must obtain and apply sufficient NMHC credits as permitted under paragraph (o)(8) of this section... conformity (see paragraph (o)(8) of this section). A manufacturer will be subject to penalties on an... covered by a certificate. (o) Requirements for the cold temperature NMHC averaging, banking and trading...

  14. Iodine Deficiency and Excess Coexist in China and Induce Thyroid Dysfunction and Disease: A Cross-Sectional Study

    PubMed Central

    Meng, Fangang; Liu, Shoujun; Fan, Zhipeng; Wu, Junhua; Sun, Dianjun

    2014-01-01

    Background In spite of the salt iodization, iodine deficiency disorders (IDD) have not been sustainably eliminated in China. There are coastal areas with low iodized salt coverage rates (iodine nutrition is inadequate) and other areas with excessive amounts of iodine in the drinking water. Objective This study aimed to clarify the association of iodine deficiencies resulting from a low coverage rate of iodized salt, excess iodine intake from drinking water with thyroid function and disease in adults. Design A cross-sectional study was conducted in adults in different iodine nutrition areas in three provinces in China. Results The prevalence of thyroid nodules was 15.52%, 8.66% and 22.17% in the iodine excess, sufficient and deficient groups, respectively. The prevalence of subclinical hypothyroidism was 20.09%, 10.41%, and 2.25% in the excess, sufficient and deficient iodine groups, respectively. The prevalence of subclinical hyperthyroidism and overt hyperthyroidism in the iodine deficient group was higher than that in the iodine excess group ( = 9.302, p = 0.002) and iodine sufficient group ( = 7.553, p = 0.006). Thyroid-stimulating hormone (TSH) was significantly correlated with excess iodine intake (β = 1.764,P = 0.001) and deficient iodine intake (β = −1.219, P = 0.028). Conclusions Thyroid nodules are more likely to be present in the iodine excess and deficient areas than in the iodine sufficient areas. Subclinical hyperthyroidism and overt hyperthyroidism are more likely to be prevalent in the iodine deficient areas than in the iodine excess or sufficient areas. Subclinical hypothyroidism is more likely to be prevalent in the high iodine intake areas than in the iodine deficient or sufficient areas. Median TSH may be deemed as an alternative indicator for monitoring the iodine nutrition status of the adult population in iodine excess and deficient areas. PMID:25375854

  15. 20 CFR 627.420 - Procurement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... (1) For purposes of this section, the term procurement means the process which leads to any award of... shall maintain records sufficient to detail the significant history of a procurement. These records...

  16. 24 CFR 581.3 - Collecting the information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... surplus, in surveys conducted by the agencies under section 202 of the Federal Property and Administrative... changed. (1) HUD will request descriptive information on properties sufficient to make a reasonable...

  17. 24 CFR 581.3 - Collecting the information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... surplus, in surveys conducted by the agencies under section 202 of the Federal Property and Administrative... changed. (1) HUD will request descriptive information on properties sufficient to make a reasonable...

  18. 24 CFR 581.3 - Collecting the information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... surplus, in surveys conducted by the agencies under section 202 of the Federal Property and Administrative... changed. (1) HUD will request descriptive information on properties sufficient to make a reasonable...

  19. 24 CFR 581.3 - Collecting the information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... surplus, in surveys conducted by the agencies under section 202 of the Federal Property and Administrative... changed. (1) HUD will request descriptive information on properties sufficient to make a reasonable...

  20. 24 CFR 581.3 - Collecting the information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... surplus, in surveys conducted by the agencies under section 202 of the Federal Property and Administrative... changed. (1) HUD will request descriptive information on properties sufficient to make a reasonable...

  1. Collaborative Cyber-infrastructures for the Management of the UNESCO-IGCP Research Project "Forecast of tephra fallout"

    NASA Astrophysics Data System (ADS)

    Folch, A.; Costa, A.; Cordoba, G.

    2009-04-01

    Tephra fallout following explosive volcanic eruptions produces several hazardous effects on inhabitants, infrastructure, and property and represents a serious threat for communities located around active volcanoes. In order to mitigate the effects on the surrounding areas, scientists and civil decision-making authorities need reliable short-term forecasts during episodes of eruptive crisis and long-term probabilistic maps to plan territorial policies and land use. Modelling, together with field studies and volcano monitoring, constitutes an indispensable tool to achieve these objectives. The UNESCO-IGCP research project proposal "Forecast of tephra fallout" has the aim to produce a series of tools capable to elaborate both short-term forecasts and long-term hazard assessments using the cutting-edge models for tephra transport and sedimentation. A special project website will be designed to supply a set of models, procedures and expertise to several Latino-American Institutes based in countries seriously threatened by this geo-hazard (Argentina, Chile, Colombia, Ecuador, Mexico, and Nicaragua). This will proportionate to the final users a tool to elaborate short-term forecasts of tephra deposition on the ground, and determine airborne ash concentrations (a quantity of special relevance for aerial navigation safety) during eruptions and emergencies. The project web-site will have a public section and a password-protected area to exchange information and data among participants and, eventually, to allow remote execution of high-resolution mesoscale meteorological forecasts at the BSC facilities. The public website section will be updated periodically and will include sections describing the project objectives and achievements as well as the hazard maps for the investigated volcanoes, and will be linked to other relevant websites such as IAVCEI, IGCP, IUGS and UNESCO homepages. A part of the public section of the website will be devoted to disseminate achieved scientific results, provide general advice, and display hazard maps to a larger public beyond the scientific community. The website private section will include a software and documentation download section as well as a gateway to run the WRF mesoscale meteorological model and the parallel version of the FALL3D model at the BSC facilities. It will be invaluable during an eventual emergency if the affected institution does not yet have an agreement with its national weather service.

  2. 75 FR 21022 - Announcement of Funding Awards for the Housing Choice Voucher Family Self-Sufficiency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ...In accordance with Section 102(a)(4)(C) of the Department of Housing and Urban Development Reform Act of 1989, this announcement notifies the public of funding decisions made by the Department for funding under Notice PIH 2009-40 (HA) for the Housing Choice Voucher Family Self-Sufficiency (HCV/FSS) Administrative Fee funding. This announcement contains the consolidated names and addresses of those award recipients selected for funding based on the funding priority categories established in the NOFA.

  3. Nontrivial paths and periodic orbits of the T-fractal billiard table

    NASA Astrophysics Data System (ADS)

    Lapidus, Michel L.; Miller, Robyn L.; Niemeyer, Robert G.

    2016-07-01

    We introduce and prove numerous new results about the orbits of the T-fractal billiard. Specifically, in section 3, we give a variety of sufficient conditions for the existence of a sequence of compatible periodic orbits. In section 4, we examine the limiting behavior of particular sequences of compatible periodic orbits. Additionally, sufficient conditions for the existence of particular nontrivial paths are given in section 4. The proofs of two results of Lapidus and Niemeyer (2013 The current state of fractal billiards Fractal Geometry and Dynamical Systems in Pure and Applied Mathematics II: Fractals in Applied Mathematics (Contemporary Mathematics vol 601) ed D Carfi et al (Providence, RI: American Mathematical Society) pp 251-88 (e-print: arXiv:math.DS.1210.0282v2, 2013) appear here for the first time, as well. In section 5, an orbit with an irrational initial direction reaches an elusive point in a way that yields a nontrivial path of finite length, yet, by our convention, constitutes a singular orbit of the fractal billiard table. The existence of such an orbit seems to indicate that the classification of orbits may not be so straightforward. A discussion of our results and directions for future research is then given in section 6.

  4. 33 CFR 154.300 - Operations manual: General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... conducting transfer operations; and (3) Includes translations into a language or languages understood by all... Manual, including a sufficient number of the translations required by paragraph (a)(3) of this section...

  5. DNA Sequences from Formalin-Fixed Nematodes: Integrating Molecular and Morphological Approaches to Taxonomy

    PubMed Central

    Thomas, W. Kelley; Vida, J. T.; Frisse, Linda M.; Mundo, Manuel; Baldwin, James G.

    1997-01-01

    To effectively integrate DNA sequence analysis and classical nematode taxonomy, we must be able to obtain DNA sequences from formalin-fixed specimens. Microdissected sections of nematodes were removed from specimens fixed in formalin, using standard protocols and without destroying morphological features. The fixed sections provided sufficient template for multiple polymerase chain reaction-based DNA sequence analyses. PMID:19274156

  6. 24 CFR 985.1 - Purpose and applicability.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the stated HUD verification method, and enrollment levels and contributions to escrow accounts for Section 8 participants under the family self-sufficiency program (FSS) (24 CFR part 984). [63 FR 48555...

  7. Pharmacogenetics and Cardiovascular Disease—Implications for Personalized Medicine

    PubMed Central

    Cavallari, Larisa H.

    2013-01-01

    The past decade has seen tremendous advances in our understanding of the genetic factors influencing response to a variety of drugs, including those targeted at treatment of cardiovascular diseases. In the case of clopidogrel, warfarin, and statins, the literature has become sufficiently strong that guidelines are now available describing the use of genetic information to guide treatment with these therapies, and some health centers are using this information in the care of their patients. There are many challenges in moving from research data to translation to practice; we discuss some of these barriers and the approaches some health systems are taking to overcome them. The body of literature that has led to the clinical implementation of CYP2C19 genotyping for clopidogrel, VKORC1, CYP2C9; and CYP4F2 for warfarin; and SLCO1B1 for statins is comprehensively described. We also provide clarity for other genes that have been extensively studied relative to these drugs, but for which the data are conflicting. Finally, we comment briefly on pharmacogenetics of other cardiovascular drugs and highlight β-blockers as the drug class with strong data that has not yet seen clinical implementation. It is anticipated that genetic information will increasingly be available on patients, and it is important to identify those examples where the evidence is sufficiently robust and predictive to use genetic information to guide clinical decisions. The review herein provides several examples of the accumulation of evidence and eventual clinical translation in cardiovascular pharmacogenetics. PMID:23686351

  8. State of the art and new developments in molecular diagnostics for hemoglobinopathies in multiethnic societies.

    PubMed

    Harteveld, C L

    2014-02-01

    For detecting carriers of thalassemia traits, the basic part of diagnostics consists of measurement of the hematological indices followed by mostly automatic separation and measurement of the Hb fractions, while direct Hb separation either on high pressure liquid chromatography or capillary electrophoresis is sufficient to putatively identify carriers of the common Hb variants like HbS, C, E, D, and O-Arab. A putative positive result is reported together with an advice for parents, partner, or family analysis. For couples, presumed at-risk confirmation at the DNA level is essential. In general, this part of diagnostics is done in specialized centers provided with sufficient experience and the technical tools needed to combine hematological and biochemical interpretation with identification of the mutations at the molecular level. State-of-the-art tools are usually available in centers that also provide prenatal diagnosis and should consist of gap-PCR for the common deletions, direct DNA sequencing for all kind of point-mutations and the capacity to uncover novel or rare mutations or disease mechanisms. New developments are MLPA for large and eventually unknown deletion defects and microarray technology for fine mapping and primer design for breakpoint analysis. Gap-PCR primers designed in the region flanking the deletion breakpoints can subsequently be used to facilitate carrier detection of uncommon deletions in family members or isolated populations in laboratories where no microarray technology or MLPA is available. © 2013 John Wiley & Sons Ltd.

  9. Perceived Safety at Work in the Wake of Terror: The Importance of Security Measures and Emergency Preparedness.

    PubMed

    Nissen, Alexander; Heir, Trond

    2016-12-01

    We aimed to explore how perceived safety after terrorism is connected to views on security measures and emergency preparedness in a workplace setting. Using a questionnaire-based, cross-sectional study of ministerial employees in Norway who were targeted in a terrorist attack in 2011 (n=3344), we investigated how employees' perceived safety at work 9 to 10 months after the attack was associated with their perceptions of whether security measures were sufficiently prioritized at work, whether there had been sufficient escape and evacuation training, and whether they were confident with evacuation procedures. We found strong evidence of increasing perceived safety at work the more employees believed security measures were sufficiently prioritized at work (partially confounded by post-traumatic stress disorder), and the better their knowledge of evacuation procedures (modified by gender and education). The present study suggests that employers may enhance perceived safety at work for terror-exposed employees by showing a commitment to security measures and by ensuring employees know evacuation procedures well. More research is needed to investigate causality patterns behind the associations found in this cross-sectional study. (Disaster Med Public Health Preparedness. 2016;10:805-811).

  10. Performance measure that indicates geometry sufficiency of state highways : volume II -- clear zones and cross-section information extraction.

    DOT National Transportation Integrated Search

    2015-03-01

    Evaluationmethod employedforthe proposed corridor projects by IndianaDepartment of Transportation(INDOT) considerroad : geometry improvements by a generalized categorization. A newmethod which consi...

  11. 14 CFR 23.773 - Pilot compartment view.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... side windows sufficiently large to provide the view specified in paragraph (a)(1) of this section... be shown that the windshield and side windows can be easily cleared by the pilot without interruption...

  12. 27 CFR 41.193 - Corporate documents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... existence or incorporation executed by the appropriate officer of the State in which incorporated. The... duplicate, will be sufficient for the purpose of this section. [T.D. ATF-422, 64 FR 71951, Dec. 22, 1999...

  13. 27 CFR 41.193 - Corporate documents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... existence or incorporation executed by the appropriate officer of the State in which incorporated. The... duplicate, will be sufficient for the purpose of this section. [T.D. ATF-422, 64 FR 71951, Dec. 22, 1999...

  14. An Experimental and Theoretical Study of Radiative Extinction of Diffusion Flames

    NASA Technical Reports Server (NTRS)

    Atreya, Arvind; Wichman, Indrek; Guenther, Mark; Ray, Anjan; Agrawal, Sanjay

    1993-01-01

    In a recent paper on 'Observations of candle flames under various atmospheres in microgravity' by Ross et al., it was found that for the same atmosphere, the burning rate per unit wick surface area and the flame temperature were considerably reduced in microgravity as compared with normal gravity. Also, the flame (spherical in microgravity) was much thicker and further removed from the wick. It thus appears that the flame becomes 'weaker' in microgravity due to the absence of buoyancy generated flow which serves to transport the oxidizer to the combustion zone and remove the hot combustion products from it. The buoyant flow, which may be characterized by the strain rate, assists the diffusion process to execute these essential functions for the survival of the flame. Thus, the diffusion flame is 'weak' at very low strain rates and as the strain rate increases the flame is initially 'strengthened' and eventually it may be 'blown out'. The computed flammability boundaries of T'ien show that such a reversal in material flammability occurs at strain rates around 5 sec. At very low or zero strain rates, flame radiation is expected to considerably affect this 'weak' diffusion flame because: (1) the concentration of combustion products which participate in gas radiation is high in the flame zone; and (2) low strain rates provide sufficient residence time for substantial amounts of soot to form which is usually responsible for a major portion of the radiative heat loss. We anticipate that flame radiation will eventually extinguish this flame. Thus, the objective of this project is to perform an experimental and theoretical investigation of radiation-induced extinction of diffusion flames under microgravity conditions. This is important for spacecraft fire safety.

  15. Research on Wheel Steel Welding Cracks Caused by Quenching Stress

    NASA Astrophysics Data System (ADS)

    Guan-nan, Li

    Wheel steel products of Han Steel occurred welding cracking when using in a wheel factory, by analyzing the crack in the wheel steel weld cracking with microstructure analysis and spectrum analysis, test results showed the grain in heat affect zone serious grow, and the user at the end of the flash-butt quenched from a high temperature to room temperature at welding seam, larger cooling rate to generate sufficiently large quenching stress, increased the risk of cracking along the grain boundary. When the stress reaches a certain level, there will be a greater area of the grain cracks at the location of welding seam, eventually leading to weld cracking. We develop measures for improvement to solving this problem, we suggest that the cooling mode at welding seam should be slow cooling or air cooling after the rim welding process, welding current range is 7800 9500 amps, upsetting time is 0.2 seconds, these measures can improve the welding quality of wheel steel products and reduce the risk of welding cracks.

  16. Beginning inflation in an inhomogeneous universe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    East, William E.; Kleban, Matthew; Linde, Andrei

    Using numerical solutions of the full Einstein field equations coupled to a scalar inflaton field in 3+1 dimensions, we study the conditions under which a universe that is initially expanding, highly inhomogeneous and dominated by gradient energy can transition to an inflationary period. If the initial scalar field variations are contained within a sufficiently flat region of the inflaton potential, and the universe is spatially flat or open on average, inflation will occur following the dilution of the gradient and kinetic energy due to expansion. This is the case even when the scale of the inhomogeneities is comparable to themore » initial Hubble length, and overdense regions collapse and form black holes, because underdense regions continue expanding, allowing inflation to eventually begin. In conclusion, this establishes that inflation can arise from highly inhomogeneous initial conditions and solve the horizon and flatness problems, at least as long as the variations in the scalar field do not include values that exceed the inflationary plateau.« less

  17. Beginning inflation in an inhomogeneous universe

    DOE PAGES

    East, William E.; Kleban, Matthew; Linde, Andrei; ...

    2016-09-06

    Using numerical solutions of the full Einstein field equations coupled to a scalar inflaton field in 3+1 dimensions, we study the conditions under which a universe that is initially expanding, highly inhomogeneous and dominated by gradient energy can transition to an inflationary period. If the initial scalar field variations are contained within a sufficiently flat region of the inflaton potential, and the universe is spatially flat or open on average, inflation will occur following the dilution of the gradient and kinetic energy due to expansion. This is the case even when the scale of the inhomogeneities is comparable to themore » initial Hubble length, and overdense regions collapse and form black holes, because underdense regions continue expanding, allowing inflation to eventually begin. In conclusion, this establishes that inflation can arise from highly inhomogeneous initial conditions and solve the horizon and flatness problems, at least as long as the variations in the scalar field do not include values that exceed the inflationary plateau.« less

  18. Beginning inflation in an inhomogeneous universe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    East, William E.; Kleban, Matthew; Linde, Andrei

    Using numerical solutions of the full Einstein field equations coupled to a scalar inflaton field in 3+1 dimensions, we study the conditions under which a universe that is initially expanding, highly inhomogeneous and dominated by gradient energy can transition to an inflationary period. If the initial scalar field variations are contained within a sufficiently flat region of the inflaton potential, and the universe is spatially flat or open on average, inflation will occur following the dilution of the gradient and kinetic energy due to expansion. This is the case even when the scale of the inhomogeneities is comparable to themore » initial Hubble length, and overdense regions collapse and form black holes, because underdense regions continue expanding, allowing inflation to eventually begin. This establishes that inflation can arise from highly inhomogeneous initial conditions and solve the horizon and flatness problems, at least as long as the variations in the scalar field do not include values that exceed the inflationary plateau.« less

  19. Suppurative bite wound by repetitive aggression of dominance hierarchy during group housing in rhesus monkeys.

    PubMed

    Choi, Yunjung; Ahn, Kyung-Ha; Lee, Jae-Il

    2014-12-01

    Group formation of rhesus monkeys, often leads to victims of repeated attacks by the high ranking animal. We reported a case of an injured middle ranking monkey from repetitive and persistent aggression. 4-male rhesus group was formed by a rapid group formation strategy 2 years ago. One monkey in the group suddenly showed depressive and reluctant movement. Physical examination revealed multiple bite wounds and scars in the dorsal skin. Overall increased opacity of the dorsal soft tissue and some free air was observed on radiographic examination. An unidentified anaerobic gram negative bacillus was isolated from the bacterial culture. Reconstructive surgery was performed and in consequence, the wound was clearly reconstructed one week later. Eventually, the afflicted monkey was separated and housed apart from the hierarchical group. This case report indicate that group formation in rhesus monkeys is essentially required sufficient time and stages, as well as more attention and a progressive contact program to reduce animal stress and fatal accidents.

  20. Remote-Controlled Release of Singlet Oxygen by the Plasmonic Heating of Endoperoxide-Modified Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy.

    PubMed

    Kolemen, Safacan; Ozdemir, Tugba; Lee, Dayoung; Kim, Gyoung Mi; Karatas, Tugce; Yoon, Juyoung; Akkaya, Engin U

    2016-03-07

    The photodynamic therapy of cancer is contingent upon the sustained generation of singlet oxygen in the tumor region. However, tumors of the most metastatic cancer types develop a region of severe hypoxia, which puts them beyond the reach of most therapeutic protocols. More troublesome, photodynamic action generates acute hypoxia as the process itself diminishes cellular oxygen reserves, which makes it a self-limiting method. Herein, we describe a new concept that could eventually lead to a change in the 100 year old paradigm of photodynamic therapy and potentially offer solutions to some of the lingering problems. When gold nanorods with tethered endoperoxides are irradiated at 808 nm, the endoperoxides undergo thermal cycloreversion, resulting in the generation of singlet oxygen. We demonstrate that the amount of singlet oxygen produced in this way is sufficient for triggering apoptosis in cell cultures. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. MRI-guided fiber-based fluorescence molecular tomography for preclinical atherosclerosis imaging

    NASA Astrophysics Data System (ADS)

    Li, Baoqiang; Pouliot, Philippe; Lesage, Frederic

    2014-09-01

    Multi-modal imaging combining fluorescent molecular tomography (FMT) with MRI could provide information in these two modalities as well as optimize the recovery of functional information with MR-guidance. Here, we present a MRI-guided FMT system. An optical probe was designed consisting of a fiber plate on the top and bottom sides of the animal bed, respectively. In experiment, animal was installed between the two plates. Mounting fibers on each plate, transmission measuring could be conducted from both sides of the animal. Moreover, an accurate fluorescence reconstruction was achieved with MRI-derived anatomical guidance. The sensitivity of the FMT system was evaluated with a phantom showing that with long fibers, it was sufficient to detect 10nM Cy5.5 solution with ~28.5 dB in the phantom. The system was eventually used to image MMP activity involved in atherosclerosis with two ATX mice and two control mice. The reconstruction results were in agreement with ex vivo measurement.

  2. Analytic study of the Tadoma method: language abilities of three deaf-blind subjects.

    PubMed

    Chomsky, C

    1986-09-01

    This study reports on the linguistic abilities of 3 adult deaf-blind subjects. The subjects perceive spoken language through touch, placing a hand on the face of the speaker and monitoring the speaker's articulatory motions, a method of speechreading known as Tadoma. Two of the subjects, deaf-blind since infancy, acquired language and learned to speak through this tactile system; the third subject has used Tadoma since becoming deaf-blind at age 7. Linguistic knowledge and productive language are analyzed, using standardized tests and several tests constructed for this study. The subjects' language abilities prove to be extensive, comparing favorably in many areas with hearing individuals. The results illustrate a relatively minor effect of limited language exposure on eventual language achievement. The results also demonstrate the adequacy of the tactile sense, in these highly trained Tadoma users, for transmitting information about spoken language sufficient to support the development of language and learning to produce speech.

  3. Space Sciences Laboratory publications and presentations, 1 January - 31 December, 1993

    NASA Technical Reports Server (NTRS)

    Moorehead, T. W.

    1994-01-01

    This document lists the significant publications and presentations of the Space Sciences Laboratory during the period January 1 to December 31, 1993. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an Appendix (arranged by report number) listing preprints issued by the Laboratory during this reporting period. Some of the preprints have not been published; those already published are so indicated. Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publications in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. The organizational code of the cognizant SSL branch or office is given at the end of each entry.

  4. Space Sciences Laboratory Publications and Presentations

    NASA Technical Reports Server (NTRS)

    Moorehead, T. W. (Compiler)

    1995-01-01

    This document lists the significant publications and presentations of the Space Sciences Laboratory during the period Jan. 1 - Dec. 31, 1994. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an appendix (arranged by report number) listing preprints issued by the laboratory during this reporting period. Some of the preprints have not been published; those already published are so indicated. Most of the articles listed under Open Literature have appeared in referenced professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publications in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. The organizational code of the cognizant SSL branch or office is given at the end of each entry.

  5. Two Instruments for Measuring Distributions of Low-Energy Charged Particles in Space

    NASA Technical Reports Server (NTRS)

    Bader, Michel; Fryer, Thomas B.; Witteborn, Fred C.

    1961-01-01

    Current estimates indicate that the bulk of interplanetary gas consists of protons with energies between 0 and 20 kev and concentrations of 1 to 105 particles/cu cm. Methods and instrumentation for measuring the energy and density distribution of such a gas are considered from the standpoint of suitability for space vehicle payloads. It is concluded that electrostatic analysis of the energy distribution can provide sufficient information in initial experiments. Both magnetic and electrostatic analyzers should eventually be used. Several instruments designed and constructed at the Ames Research Center for space plasma measurements, and the methods of calibration and data reduction are described. In particular, the instrument designed for operation on solar cell power has the following characteristics: weight, 1.1 pounds; size, 2 by 3 by 4 inches; and power consumption, 145 mw. The instrument is designed to yield information on the concentration, energy distribution, and the anisotropy of ion trajectories in the 0.2 to 20 kev range.

  6. 3D Power Line Extraction from Multiple Aerial Images.

    PubMed

    Oh, Jaehong; Lee, Changno

    2017-09-29

    Power lines are cables that carry electrical power from a power plant to an electrical substation. They must be connected between the tower structures in such a way that ensures minimum tension and sufficient clearance from the ground. Power lines can stretch and sag with the changing weather, eventually exceeding the planned tolerances. The excessive sags can then cause serious accidents, while hindering the durability of the power lines. We used photogrammetric techniques with a low-cost drone to achieve efficient 3D mapping of power lines that are often difficult to approach. Unlike the conventional image-to-object space approach, we used the object-to-image space approach using cubic grid points. We processed four strips of aerial images to automatically extract the power line points in the object space. Experimental results showed that the approach could successfully extract the positions of the power line points for power line generation and sag measurement with the elevation accuracy of a few centimeters.

  7. 3D Power Line Extraction from Multiple Aerial Images

    PubMed Central

    Lee, Changno

    2017-01-01

    Power lines are cables that carry electrical power from a power plant to an electrical substation. They must be connected between the tower structures in such a way that ensures minimum tension and sufficient clearance from the ground. Power lines can stretch and sag with the changing weather, eventually exceeding the planned tolerances. The excessive sags can then cause serious accidents, while hindering the durability of the power lines. We used photogrammetric techniques with a low-cost drone to achieve efficient 3D mapping of power lines that are often difficult to approach. Unlike the conventional image-to-object space approach, we used the object-to-image space approach using cubic grid points. We processed four strips of aerial images to automatically extract the power line points in the object space. Experimental results showed that the approach could successfully extract the positions of the power line points for power line generation and sag measurement with the elevation accuracy of a few centimeters. PMID:28961204

  8. Dynamics in atomic signaling games.

    PubMed

    Fox, Michael J; Touri, Behrouz; Shamma, Jeff S

    2015-07-07

    We study an atomic signaling game under stochastic evolutionary dynamics. There are a finite number of players who repeatedly update from a finite number of available languages/signaling strategies. Players imitate the most fit agents with high probability or mutate with low probability. We analyze the long-run distribution of states and show that, for sufficiently small mutation probability, its support is limited to efficient communication systems. We find that this behavior is insensitive to the particular choice of evolutionary dynamic, a property that is due to the game having a potential structure with a potential function corresponding to average fitness. Consequently, the model supports conclusions similar to those found in the literature on language competition. That is, we show that efficient languages eventually predominate the society while reproducing the empirical phenomenon of linguistic drift. The emergence of efficiency in the atomic case can be contrasted with results for non-atomic signaling games that establish the non-negligible possibility of convergence, under replicator dynamics, to states of unbounded efficiency loss. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Reader error, object recognition, and visual search

    NASA Astrophysics Data System (ADS)

    Kundel, Harold L.

    2004-05-01

    Small abnormalities such as hairline fractures, lung nodules and breast tumors are missed by competent radiologists with sufficient frequency to make them a matter of concern to the medical community; not only because they lead to litigation but also because they delay patient care. It is very easy to attribute misses to incompetence or inattention. To do so may be placing an unjustified stigma on the radiologists involved and may allow other radiologists to continue a false optimism that it can never happen to them. This review presents some of the fundamentals of visual system function that are relevant to understanding the search for and the recognition of small targets embedded in complicated but meaningful backgrounds like chests and mammograms. It presents a model for visual search that postulates a pre-attentive global analysis of the retinal image followed by foveal checking fixations and eventually discovery scanning. The model will be used to differentiate errors of search, recognition and decision making. The implications for computer aided diagnosis and for functional workstation design are discussed.

  10. Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

    NASA Astrophysics Data System (ADS)

    Liou, Geou-Yarh; Döppler, Heike; Braun, Ursula B.; Panayiotou, Richard; Scotti Buzhardt, Michele; Radisky, Derek C.; Crawford, Howard C.; Fields, Alan P.; Murray, Nicole R.; Wang, Q. Jane; Leitges, Michael; Storz, Peter

    2015-02-01

    The transdifferentiation of pancreatic acinar cells to a ductal phenotype (acinar-to-ductal metaplasia, ADM) occurs after injury or inflammation of the pancreas and is a reversible process. However, in the presence of activating Kras mutations or persistent epidermal growth factor receptor (EGF-R) signalling, cells that underwent ADM can progress to pancreatic intraepithelial neoplasia (PanIN) and eventually pancreatic cancer. In transgenic animal models, ADM and PanINs are initiated by high-affinity ligands for EGF-R or activating Kras mutations, but the underlying signalling mechanisms are not well understood. Here, using a conditional knockout approach, we show that protein kinase D1 (PKD1) is sufficient to drive the reprogramming process to a ductal phenotype and progression to PanINs. Moreover, using 3D explant culture of primary pancreatic acinar cells, we show that PKD1 acts downstream of TGFα and Kras, to mediate formation of ductal structures through activation of the Notch pathway.

  11. Galaxy And Mass Assembly (GAMA): blue spheroids within 87 Mpc

    NASA Astrophysics Data System (ADS)

    Mahajan, Smriti; Drinkwater, Michael J.; Driver, S.; Hopkins, A. M.; Graham, Alister W.; Brough, S.; Brown, Michael J. I.; Holwerda, B. W.; Owers, Matt S.; Pimbblet, Kevin A.

    2018-03-01

    In this paper, we test if nearby blue spheroid (BSph) galaxies may become the progenitors of star-forming spiral galaxies or passively evolving elliptical galaxies. Our sample comprises 428 galaxies of various morphologies in the redshift range 0.002 < z < 0.02 (8-87 Mpc) with panchromatic data from the Galaxy and Mass Assembly survey. We find that BSph galaxies are structurally (mean effective surface brightness, effective radius) very similar to their passively evolving red counterparts. However, their star formation and other properties such as colour, age, and metallicity are more like star-forming spirals than spheroids (ellipticals and lenticulars). We show that BSph galaxies are statistically distinguishable from other spheroids as well as spirals in the multidimensional space mapped by luminosity-weighted age, metallicity, dust mass, and specific star formation rate. We use H I data to reveal that some of the BSphs are (further) developing their discs, hence their blue colours. They may eventually become spiral galaxies - if sufficient gas accretion occurs - or more likely fade into low-mass red galaxies.

  12. Transition to turbulence under low-pressure turbine conditions.

    PubMed

    Simon, T W; Kaszeta, R W

    2001-05-01

    In this paper, the topic of laminar to turbulent flow transition, as applied to the design of gas turbines, is discussed. Transition comes about when a flow becomes sufficiently unstable that the orderly vorticity structure of the laminar layer becomes randomly oriented. Vorticity with a streamwise component leads to rapid growth of eddies of a wide range of sizes and eventually to turbulent flow. Under "natural" transition, infinitesimal disturbances of selected frequencies grow. "Bypass transition" is a term coined to describe a similar process, but one driven by strong external disturbances. Transition proceeds so rapidly that the processes associated with "natural" transition seem to be "bypassed." Because the flow environment in the turbine is disturbed by wakes from upstream airfoils, eddies from combustor flows, jets from film cooling, separation zones on upstream airfoils and steps in the duct walls, transition is of the bypass mode. In this paper, we discuss work that has been done to characterize and model bypass transition, as applied to the turbine environment.

  13. Assessing the performance of LOINC® and RadLex for coverage of CT scans across three sites in a health information exchange.

    PubMed

    Beitia, Anton Oscar; Kuperman, Gilad; Delman, Bradley N; Shapiro, Jason S

    2013-01-01

    We evaluated the performance of LOINC® and RadLex standard terminologies for covering CT test names from three sites in a health information exchange (HIE) with the eventual goal of building an HIE-based clinical decision support system to alert providers of prior duplicate CTs. Given the goal, the most important parameter to assess was coverage for high frequency exams that were most likely to be repeated. We showed that both LOINC® and RadLex provided sufficient coverage for our use case through calculations of (a) high coverage of 90% and 94%, respectively for the subset of CTs accounting for 99% of exams performed and (b) high concept token coverage (total percentage of exams performed that map to terminologies) of 92% and 95%, respectively. With trends toward greater interoperability, this work may provide a framework for those wishing to map radiology site codes to a standard nomenclature for purposes of tracking resource utilization.

  14. Role of ozone and granular activated carbon in the removal of mutagenic compounds.

    PubMed Central

    Bourbigot, M M; Hascoet, M C; Levi, Y; Erb, F; Pommery, N

    1986-01-01

    The identification of certain organic compounds in drinking water has led water treatment specialists to be increasingly concerned about the eventual risks of such pollutants to the health of consumers. Our experiments focused on the role of ozone and granular activated carbon in removing mutagenic compounds and precursors that become toxic after chlorination. We found that if a sufficient dose of ozone is applied, its use does not lead to the creation of mutagenic compounds in drinking water and can even eliminate the initial mutagenicity of the water. The formation of new mutagenic compounds seems to be induced by ozonation that is too weak, although these mutagens can be removed by GAC filtration. Ozone used with activated carbon can be one of the best means for eliminating the compounds contributing to the mutagenicity of water. A combined treatment of ozone and activated carbon also decreases the chlorine consumption of the treated water and consequently reduces the formation of chlorinated organic compounds. PMID:3816720

  15. Space Science Laboratory Publications and Presentations

    NASA Technical Reports Server (NTRS)

    Moorehead, T. W. (Compiler)

    1993-01-01

    This document lists the significant publications and presentations of the Space Science Laboratory during the period January 1 - December 31, 1992. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Also included for completeness is an Appendix (arranged by report number) listing preprints issued by the Laboratory during this reporting period. Some of the preprints have not been published; those already published are so indicated. Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publications in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature. The organizational code of the cognizant SSL branch or office is given at the end of each entry.

  16. Toward large space systems. [Space Construction Base development from shuttles

    NASA Technical Reports Server (NTRS)

    Daros, C. J.; Freitag, R. F.; Kline, R. L.

    1977-01-01

    The design of the Space Transportation System, consisting of the Space Shuttle, Spacelab, and upper stages, provides experience for the development of more advanced space systems. The next stage will involve space stations in low earth orbit with limited self-sufficiency, characterized by closed ecological environments, space-generated power, and perhaps the first use of space materials. The third phase would include manned geosynchronous space-station activity and a return to lunar operations. Easier access to space will encourage the use of more complex, maintenance-requiring satellites than those currently used. More advanced space systems could perform a wide range of public services such as electronic mail, personal and police communication, disaster control, earthquake detection/prediction, water availability indication, vehicle speed control, and burglar alarm/intrusion detection. Certain products, including integrated-circuit chips and some enzymes, can be processed to a higher degree of purity in space and might eventually be manufactured there. Hardware including dishes, booms, and planar surfaces necessary for advanced space systems and their development are discussed.

  17. XAssist: A System for the Automation of X-ray Astrophysics Analysis

    NASA Astrophysics Data System (ADS)

    Ptak, A.

    2004-08-01

    XAssist is a NASA AISR-funded project for the automation of X-ray astrophysics. It is capable of data reprocessing, source detection, and preliminary spatial, temporal and spectral analysis for each source with sufficient counts. The bulk of the system is written in Python, which in turn drives underlying software (CIAO for Chandra data, etc.). Future work will include a GUI (mainly for beginners and status monitoring) and the exposure of at least some functionality as web services. The latter will help XAssist to eventually become part of the VO, making advanced queries possible, such as determining the X-ray fluxes of counterparts to HST or SDSS sources (including the use of unpublished X-ray data), and add the ability of ``on-the-fly'' X-ray processing. Pipelines are running on Chandra and XMM-Newton observations of galaxies to demonstrate XAssist's capabilities, and the results are available online (in real time) at http://www.xassist.org. XAssist itself as well as various associated projects are available for download.

  18. Chryse Basin channels: low-gradients and ponded flows.

    USGS Publications Warehouse

    Lucchitta, B.K.; Ferguson, H.M.

    1983-01-01

    Gradients on the floors of the Martian outflow channels that are derived from radar-elevation profiles across Lunae Planum and Chryse Basin have much lower values than those obtained from the U.S. Geological Survey's topographic map. Whereas the gradients of Maja and Ares Valles are similar to those of the catastrophic flood channels in the Scablands of Washington State, the gradients of Simud and Tiu Valles are essentially level, and the movement of fluids to the N poses problems. It is proposed that ponding may have formed lakes in depressions associated with the Valles Marineris grabens, ancient craters in the chaotic terrain area, and possibly even the regional low where most chaotic terrains occur. It is envisaged that lakes eventually overflowed, forming the present channels. When dams broke, floods were released catastrophically, with a final gigantic flood from the Valles Marineris system of troughs, which would have had sufficient head to move fluids across nearly level gradients through the Simud and Tiu channels. -P.Br.

  19. Research on red tide occurrences using enclosed experimental ecosystems in west Xiamen Harbor, China—Relationship between various factors and red tide occurrences

    NASA Astrophysics Data System (ADS)

    Lin, Yu; Harrison, P. J.

    2000-06-01

    A series of enclosed ecosystem experiments were conducted in a land-based tank near the seaside of West Xiamen Harbor. The results of experiments conducted in different seasons and years showed a repeatable phytoplankton succession. In this relatively stable ecosystem with added nutrients and trace metals, diatoms dominated initially, dinoflagellates dominated in the later stage, and dinoflagellate red tides eventually occurred. Vitamin B12 enrichment may speed up this succession process. Stirring the water column could stop this process. Soluble Mn at a level of 3 4 μg/L in seawater, which also is the existing concentration of soluble Mn in Xiamen Harbor seawater, is sufficient for the multiplication of algae and occurrence of red tide. The present study showed that excessive soluble Mn in Xiamen Harbor cannot cause red tide, and that Fe was one of the important factors causing diatiom red tide in this present study.

  20. Theory of twisted nonuniformly heated bars

    NASA Technical Reports Server (NTRS)

    Shorr, B. F.

    1980-01-01

    Nonlineary distributed stresses in twisted nonuniformly heated bars of arbitrary cross section are calculated taking into account various elasticity parameters. The approximate theory is shown to be sufficiently general and accurate by comparison with experimental data.

  1. 36 CFR 13.1310 - Pets.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) The restrictions in this section do not apply to dogs when sufficient snow exists for skiing or dog sled use and the dogs are restrained as part of a sled dog team or for the purposes of skijoring. ...

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kin, Tadahiro; Oshima, Masumi; Furutaka, Kazuyoshi

    We developed a spectrometer for multiple prompt gamma-ray measurements to identify nuclear levels to determine neutron capture cross sections. From a test of finding candidates of {sup 15}N levels with a developing method, we found performance of the spectrometer is sufficient.

  3. 10 CFR 35.491 - Training for ophthalmic use of strontium-90.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...; (iii) Mathematics pertaining to the use and measurement of radioactivity; and (iv) Radiation biology... the requirements in paragraph (b) of this section and has achieved a level of competency sufficient to...

  4. Performance evaluation of rotating pump jet mixing of radioactive wastes in Hanford Tanks 241-AP-102 and -104

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Onishi, Y.; Recknagle, K.P.

    The purpose of this study was to confirm the adequacy of a single mixer pump to fully mix the wastes that will be stored in Tanks 241-AP-102 and -104. These Hanford double-shell tanks (DSTs) will be used as staging tanks to receive low-activity wastes from other Hanford storage tanks and, in turn, will supply the wastes to private waste vitrification facilities for eventual solidification. The TEMPEST computer code was applied to Tanks AP-102 and -104 to simulate waste mixing generated by the 60-ft/s rotating jets and to determine the effectiveness of the single rotating pump to mix the waste. TEMPESTmore » simulates flow and mass/heat transport and chemical reactions (equilibrium and kinetic reactions) coupled together. Section 2 describes the pump jet mixing conditions the authors evaluated, the modeling cases, and their parameters. Section 3 reports model applications and assessment results. The summary and conclusions are presented in Section 4, and cited references are listed in Section 5.« less

  5. Image selection in static telepathology through the Internet.

    PubMed

    Della Mea, V; Cataldi, P; Boi, S; Finato, N; Della Palma, P; Beltrami, C A

    1998-01-01

    A telepathology study was carried out to examine the differences occurring when the images were selected by an experienced pathologist, a junior pathologist and a first-year resident. One hundred and fifty-five consecutive frozen-section pathology cases were collected and sent for consultation to a remote experienced pathologist using multimedia email. Local diagnoses (as reported in the files of the Institute, not from the image selector) and remote diagnoses (based on the images) were compared with those performed on paraffin-embedded sections. Acquisition time and number of selected images were recorded for each case and used to compare the different behaviour of the three local pathologists. Of the 155 cases sent by telepathology, four were considered insufficient for a diagnosis by the remote pathologist and thus the diagnosis was postponed. In the remaining 151 cases, the overall diagnostic agreement between remote and definitive diagnosis was 96.7%. The results indicate that in the routine diagnostic work of a frozen-section service, an inexperienced pathologist can select images which are sufficiently informative for a remote diagnosis, in a sufficiently short time.

  6. 78 FR 28606 - Announcement of Funding Awards for the Housing Choice Voucher Family Self-Sufficiency (HCV FSS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ...In accordance with Section 102(a)(4)(C) of the Department of Housing and Urban Development Reform Act of 1989, this announcement notifies the public of funding decisions made by the Department for funding under the Fiscal Year 2012 (FY2012) Notice of Funding Availability (NOFA) for the Housing Choice Voucher Family Self-Sufficiency (HCV-FSS) program. This announcement contains the consolidated names and addresses of those award recipients selected for funding based on the funding priority categories established in the NOFA.

  7. Pathologic Markers Determining Prognosis in Patients with Treated or Healing Giant Cell Arteritis.

    PubMed

    Sultan, Harris; Smith, Stacy V; Lee, Andrew G; Chévez-Barrios, Patricia

    2018-06-08

    To provide quantitative evidence linking the Cluster of Differentiation-68 (CD68)+ macrophage-marker found on temporal artery biopsies (TABs) with disease prognosis. Retrospective, cross-sectional study METHODS: We examined 42 consecutive patients who had undergone unilateral TABs at a single hospital in 2015. Clinical data, laboratory data, and histopathologic features of TABs were recorded. clinical diagnosis of giant cell arteritis (GCA) with TAB performed at the same center. CD68 immunohistochemistry was used to label macrophages in the TABs. multiple logistic regression and bivariate comparisons to measure the association between CD68+ cells per histologic section with placement on immunomodulatory therapy (IMT). Twenty seven patients were females (64%), with a mean age of 72 (standard deviation [S.D.] ±7.7). Eleven patients (26%) were placed on IMT, 17 (40%) had disease recurrence during steroid taper, and 25 (60%) were referred to rheumatology. Of 42 biopsies, 35 underwent staining with CD68 to confirm active inflammation in suspicious, but not diagnostic, specimens. Patients eventually placed on IMT had increased CD68+ cells/slice compared to those not on IMT (median 5.00 [25-75 th quartile 2.00-7.15] vs 1.21 [0.38-2.57], p=0.031, respectively). A receiver operating characteristics (ROC) curve demonstrates that 2.17 CD68+ cells/slice predicts placement on IMT with an odds ratio of 1.54 (95% C.I. 1.02-2.33, p=0.038). Patients refractory to initial steroid tapers and those eventually placed on IMT had increased CD68 cells/section. CD68+ macrophages and their location on the internal elastic lamina may predict disease severity in patients with presumed GCA. Our results suggest that this marker may expedite patient triaging to alternate treatment to the usual steroid therapy. Copyright © 2018 Elsevier Inc. All rights reserved.

  8. Quasi-heterogeneous efficient 3-D discrete ordinates CANDU calculations using Attila

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Preeti, T.; Rulko, R.

    2012-07-01

    In this paper, 3-D quasi-heterogeneous large scale parallel Attila calculations of a generic CANDU test problem consisting of 42 complete fuel channels and a perpendicular to fuel reactivity device are presented. The solution method is that of discrete ordinates SN and the computational model is quasi-heterogeneous, i.e. fuel bundle is partially homogenized into five homogeneous rings consistently with the DRAGON code model used by the industry for the incremental cross-section generation. In calculations, the HELIOS-generated 45 macroscopic cross-sections library was used. This approach to CANDU calculations has the following advantages: 1) it allows detailed bundle (and eventually channel) power calculationsmore » for each fuel ring in a bundle, 2) it allows the exact reactivity device representation for its precise reactivity worth calculation, and 3) it eliminates the need for incremental cross-sections. Our results are compared to the reference Monte Carlo MCNP solution. In addition, the Attila SN method performance in CANDU calculations characterized by significant up scattering is discussed. (authors)« less

  9. 47 CFR 15.305 - Equipment authorization requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 15.305 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unlicensed Personal Communications Service Devices § 15.305 Equipment authorization requirement. PCS devices... 2 of this chapter before marketing. The application for certification must contain sufficient...

  10. 47 CFR 15.305 - Equipment authorization requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 15.305 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unlicensed Personal Communications Service Devices § 15.305 Equipment authorization requirement. PCS devices... 2 of this chapter before marketing. The application for certification must contain sufficient...

  11. Sub-micron resolution rf cavity beam position monitor system at the SACLA XFEL facility

    NASA Astrophysics Data System (ADS)

    Maesaka, H.; Ego, H.; Inoue, S.; Matsubara, S.; Ohshima, T.; Shintake, T.; Otake, Y.

    2012-12-01

    We have developed and constructed a C-band (4.760 GHz) rf cavity beam position monitor (RF-BPM) system for the XFEL facility at SPring-8, SACLA. The demanded position resolution of the RF-BPM is less than 1 μm, because an electron beam and x-rays must be overlapped within 4 μm precision in the undulator section for sufficient FEL interaction between the electrons and x-rays. In total, 57 RF-BPMs, including IQ demodulators and high-speed waveform digitizers for signal processing, were produced and installed into SACLA. We evaluated the position resolutions of 20 RF-BPMs in the undulator section by using a 7 GeV electron beam having a 0.1 nC bunch charge. The position resolution was measured to be less than 0.6 μm, which was sufficient for the XFEL lasing in the wavelength region of 0.1 nm, or shorter.

  12. Context and Content Aware Routing of Managed Information Objects

    DTIC Science & Technology

    2014-05-01

    datatype . Siena, however, does not support incremental updates (i.e., subscription posting and deletion) and so updates must be done in batch mode...Although the present implementation of PUBSUB does not support the string datatype , its architecture is sufficiently versatile to accommodate this... datatype with the inclusion of additional data structures as de- scribed in Section 3. 3. PUBSUB Section 3.1 describes how PUBSUB organizes its database of

  13. Combustion of interacting droplet arrays in a microgravity environment

    NASA Technical Reports Server (NTRS)

    Dietrich, Daniel L.; Haggard, John B.

    1993-01-01

    This research program involves the study of one and two dimensional arrays of droplets in a buoyant-free environment. The purpose of the work is to extend the database and theories that exist for single droplets into the regime where droplet interactions are important. The eventual goal being to use the results of this work as inputs to models on spray combustion where droplets seldom burn individually; instead the combustion history of a droplet is strongly influenced by the presence of the neighboring droplets. The emphasis of the present investigation is experimental, although comparison will be made to existing theoretical and numerical treatments when appropriate. Both normal gravity and low gravity testing will be employed, and the results compared. The work to date will be summarized in the next section, followed by a section detailing the future plans.

  14. Flame front propagation in a channel with porous walls

    NASA Astrophysics Data System (ADS)

    Golovastov, S. V.; Bivol, G. Yu

    2016-11-01

    Propagation of the detonation front in hydrogen-air mixture was investigated in rectangular cross-section channels with sound-absorbing boundaries. The front of luminescence was detected in a channel with acoustically absorbing walls as opposed to a channel with solid walls. Flame dynamics was recorded using a high-speed camera. The flame was observed to have a V-shaped profile in the acoustically absorbing section. The possible reason for the formation of the V-shaped flame front is friction under the surface due to open pores. In these shear flows, the kinetic energy of the flow on the surface can be easily converted into heat. A relatively small disturbance may eventually lead to significant local stretching of the flame front surface. Trajectories of the flame front along the axis and the boundary are presented for solid and porous surfaces.

  15. Super low NO.sub.x, high efficiency, compact firetube boiler

    DOEpatents

    Chojnacki, Dennis A.; Rabovitser, Iosif K.; Knight, Richard A.; Cygan, David F.; Korenberg, Jacob

    2005-12-06

    A firetube boiler furnace having two combustion sections and an in-line intermediate tubular heat transfer section between the two combustion sections and integral to the pressure vessel. This design provides a staged oxidant combustion apparatus with separate in-line combustion chambers for fuel-rich primary combustion and fuel-lean secondary combustion and sufficient cooling of the combustion products from the primary combustion such that when the secondary combustion oxidant is added in the secondary combustion stage, the NO.sub.x formation is less than 5 ppmv at 3% O.sub.2.

  16. 7 CFR 29.6018 - Grade.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Grade. 29.6018 Section 29.6018 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... to other characteristics when they are of sufficient importance to be treated separately. ...

  17. 29 CFR 2200.68 - Disqualification of the Judge.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... party may request the Judge, at any time following his designation and before the filing of his decision... referred to in paragraph (b) of this section is filed with due diligence and is sufficient on its face, the...

  18. 75 FR 8768 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... duplicates the requirement in Section 22(d) of the Investment Company Act to sell mutual fund shares to... requiring the deposit of sufficient funds within the specified payment period. FINRA also stated that the...

  19. 47 CFR 18.109 - General technical requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false General technical requirements. 18.109 Section 18.109 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... designed and constructed in accordance with good engineering practice with sufficient shielding and...

  20. 47 CFR 18.109 - General technical requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false General technical requirements. 18.109 Section 18.109 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... designed and constructed in accordance with good engineering practice with sufficient shielding and...

  1. 47 CFR 18.109 - General technical requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false General technical requirements. 18.109 Section 18.109 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... designed and constructed in accordance with good engineering practice with sufficient shielding and...

  2. 47 CFR 18.109 - General technical requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false General technical requirements. 18.109 Section 18.109 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... designed and constructed in accordance with good engineering practice with sufficient shielding and...

  3. 47 CFR 18.109 - General technical requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false General technical requirements. 18.109 Section 18.109 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND... designed and constructed in accordance with good engineering practice with sufficient shielding and...

  4. Bridge deck deterioration study : final report.

    DOT National Transportation Integrated Search

    1975-03-01

    The basic purpose of this study was to investigate three bridges in the northern section of Louisiana in an attempt to determine if there is sufficient deterioration and corrosion of the reinforcing steel to warrant a comprehensive study of bridge de...

  5. Modeling the double charge exchange response function for a tetraneutron system

    NASA Astrophysics Data System (ADS)

    Lazauskas, R.; Carbonell, J.; Hiyama, E.

    2017-07-01

    This work is an attempt to model the 4 n response function of a recent RIKEN experimental study of the double charge exchange  4 He( 8 He, 8 Be) 4n reaction in order to put in evidence an eventual enhancement mechanism of the zero-energy cross section, including a near-threshold resonance. This resonance can indeed be reproduced only by adding to the standard nuclear Hamiltonian an unphysically large T =3/2 attractive 3 n -force that destroys the neighboring nuclear chart. No other mechanisms, like cusps or related structures, were found.

  6. Fatal hemothorax following management of an esophageal foreign body.

    PubMed

    Cohn, Leah A; Stoll, Melissa R; Branson, Keith R; Roudabush, Alice D; Kerl, Marie E; Langdon, Paige F; Johannes, Chad M

    2003-01-01

    A 10.8-year-old, spayed female toy poodle presented with an esophageal foreign body. The foreign body was removed endoscopically, and a gastrostomy tube was placed to provide nutritional support during esophageal healing. The gastrostomy tube was later removed by endoscopic retrieval of the bulb through the esophagus. Immediately afterward, the dog developed hemothorax and eventually died. It was determined that many small arterial branches were avulsed from the aorta. The involved sections of aorta histopathogically evidenced medial necrosis, which was believed to be related to a prior disruption of blood flow through the vasa vasorum.

  7. Atomic Number Dependence of Hadron Production at Large Transverse Momentum in 300 GeV Proton--Nucleus Collisions

    DOE R&D Accomplishments Database

    Cronin, J. W.; Frisch, H. J.; Shochet, M. J.; Boymond, J. P.; Mermod, R.; Piroue, P. A.; Sumner, R. L.

    1974-07-15

    In an experiment at the Fermi National Accelerator Laboratory we have compared the production of large transverse momentum hadrons from targets of W, Ti, and Be bombarded by 300 GeV protons. The hadron yields were measured at 90 degrees in the proton-nucleon c.m. system with a magnetic spectrometer equipped with 2 Cerenkov counters and a hadron calorimeter. The production cross-sections have a dependence on the atomic number A that grows with P{sub 1}, eventually leveling off proportional to A{sup 1.1}.

  8. Minimum-fuel, 3-dimensional flightpath guidance of transfer jets

    NASA Technical Reports Server (NTRS)

    Neuman, F.; Kreindler, E.

    1984-01-01

    Minimum fuel, three dimensional flightpaths for commercial jet aircraft are discussed. The theoretical development is divided into two sections. In both sections, the necessary conditions of optimal control, including singular arcs and state constraints, are used. One section treats the initial and final portions (below 10,000 ft) of long optimal flightpaths. Here all possible paths can be derived by generating fields of extremals. Another section treats the complete intermediate length, three dimensional terminal area flightpaths. Here only representative sample flightpaths can be computed. Sufficient detail is provided to give the student of optimal control a complex example of a useful application of optimal control theory.

  9. School Teams up for SSP Functional Models

    NASA Astrophysics Data System (ADS)

    Pignolet, G.; Lallemand, R.; Celeste, A.; von Muldau, H.

    2002-01-01

    Space Solar Power systems appear increasingly as one of the major solutions to the upcoming global energy crisis, by collecting solar energy in space where this is most easy, and sending it by microwave beam to the surface of the planet, where the need for controlled energy is located. While fully operational systems are still decades away, the need for major development efforts is with us now. Yet, for many decision-makers and for most of the public, SSP often still sounds like science fiction. Six functional demonstration systems, based on the Japanese SPS-2000 concept, have been built as a result of a cooperation between France and Japan, and they are currently used extensively, in Japan, in Europe and in North America, for executive presentations as well as for public exhibitions. There is demand for more models, both for science museums and for use by energy dedicated groups, and a senior high school in La Reunion, France, has picked up the challenge to make the production of such models an integrated practical school project for pre-college students. In December 2001, the administration and the teachers of the school have evaluated the feasibility of the project and eventually taken the go decision for the school year 2002- 2003, when for education purposes a temporary "school business company" will be incorporated with the goal to study and manufacture a limited series of professional quality SSP demonstration models, and to sell them world- wide to institutions and advocacy groups concerned with energy problems and with the environment. The different sections of the school will act as the different services of an integrated business : based on the current existing models, the electronic section will redesign the energy management system and the microwave projector module, while the mechanical section of the school will adapt and re-conceive the whole packaging of the demonstrator. The French and foreign language sections will write up a technical manual for the operation of the model and a guide to assist users with the basics of space solar power, with versions both in French and in English. The students of the commercial section will conduct global marketing and later handle international sales. Technical and market studies will take place at the end of the year 2002, while actual production, currently estimated at some twenty units, will take place during the first part of 2003. Initial operation will be assisted by institutional support and subscription sales from already identified customers, but later the operation will be self supporting, with eventually some cash benefit the school like in any normal commercial operation, before the "company" eventually will shut down its operation at the end of the school year in June 2003. The benefits of this high level "hands-on" operation will be very important, first because of the promotion of the SSP concepts and the understanding of the potential from space that it will foster. But the greatest reward will be for the students and the teachers involved in the operation, both simple and very complex at the same time, because they will integrate all the aspects of a "real" professional activity, around the great futuristic concept of providing clean and sustainable energy for Mankind and for the Earth...

  10. [Structural quality in psychiatric and psychotherapeutic hospitals].

    PubMed

    Klimke, A; Godemann, F; Hauth, I; Deister, A

    2015-05-01

    The new German flat rate reimbursement system for psychiatry and psychosomatics (PEPP) is primarily based on the diagnostic classification and the costs of therapeutic processes. In 2019 the current normative standard for calculating the therapeutic staff in psychiatric clinics (Psych-PV) will be substituted by a stepwise adaptation process over 5 years. Using regionally calculated remuneration factors, all clinic budgets should eventually converge to comparable values. Major factors influencing the structural quality of therapy in psychiatric clinics are identified and recommendations are given to support the work of the Federal Joint Committee (G-BA) which has been appointed to develop new recommendations for the minimum setting of personnel requirements. The full reimbursement of the necessary staff and of the costs resulting from outsourcing of day clinics and outpatient departments in the community, including the obligation to treat psychiatric emergency patients is mandatory and currently not sufficiently guaranteed in the new PEPP system. A workflow which opens the possibility to finance therapeutic innovations (e.g. psychotherapy) and helps to overcome the financial sectorial boundaries between inpatient and outpatient treatment is also missing. A mandatory recommendation for minimum staff settings needs a guaranteed full financing from the political side. Additionally, important would be an option for financing of therapeutic innovations and increased costs because of changed patient structures with respect to diagnosis and severity. Moreover, a sufficient remuneration for regional treatment responsibilities and for additional financial outlay resulting from structural costs for regionally outsourced departments is needed to avoid supplementary financing by reducing the budget for the therapeutic staff.

  11. The BMP pathway acts to directly regulate Tbx20 in the developing heart

    PubMed Central

    Mandel, Elizabeth M.; Kaltenbrun, Erin; Callis, Thomas E.; Zeng, Xin-Xin I.; Marques, Sara R.; Yelon, Deborah; Wang, Da-Zhi; Conlon, Frank L.

    2010-01-01

    TBX20 has been shown to be essential for vertebrate heart development. Mutations within the TBX20 coding region are associated with human congenital heart disease, and the loss of Tbx20 in a wide variety of model systems leads to cardiac defects and eventually heart failure. Despite the crucial role of TBX20 in a range of cardiac cellular processes, the signal transduction pathways that act upstream of Tbx20 remain unknown. Here, we have identified and characterized a conserved 334 bp Tbx20 cardiac regulatory element that is directly activated by the BMP/SMAD1 signaling pathway. We demonstrate that this element is both necessary and sufficient to drive cardiac-specific expression of Tbx20 in Xenopus, and that blocking SMAD1 signaling in vivo specifically abolishes transcription of Tbx20, but not that of other cardiac factors, such as Tbx5 and MHC, in the developing heart. We further demonstrate that activation of Tbx20 by SMAD1 is mediated by a set of novel, non-canonical, high-affinity SMAD-binding sites located within this regulatory element and that phospho-SMAD1 directly binds a non-canonical SMAD1 site in vivo. Finally, we show that these non-canonical sites are necessary and sufficient for Tbx20 expression in Xenopus, and that reporter constructs containing these sites are expressed in a cardiac-specific manner in zebrafish and mouse. Collectively, our findings define Tbx20 as a direct transcriptional target of the BMP/SMAD1 signaling pathway during cardiac maturation. PMID:20460370

  12. New York can be our nation's center for Alzheimer's research.

    PubMed

    Vann, Allan S

    2014-09-01

    More than 5 million people in this country have Alzheimer's disease, and more than 300,000 of those with Alzheimer's live in New York. By 2025, it is estimated that there will be 350,000 residents living with Alzheimer's in New York. Congressman Steve Israel and New York Assemblyman Charles Lavine issued a joint proposal in June, 2013 suggesting that New York become this country's center for Alzheimer's research. Obviously, they would both like to see increased federal funding, but they also know that we cannot count on that happening. So Israel and Lavine have proposed a $3 billion state bonding initiative to secure sufficient funding to tackle this disease. It would be similar to the bonding initiatives that have made California and Texas this nation's centers for stem cell and cancer research. The bond would provide a dedicated funding stream to support research to find effective means to treat, cure, and eventually prevent Alzheimer's, and fund programs to help people currently dealing with Alzheimer's and their caregivers. New York already has some of the major "ingredients" to make an Alzheimer's bond initiative a success, including 3 of our nation's 29 Alzheimer's Disease Research Centers and some of the finest research facilities in the nation for genetic and neuroscience research. One can only imagine the synergy of having these world class institutions working on cooperative grants and projects with sufficient funding to attract even more world class researchers and scientists to New York to find ways to prevent, treat, and cure Alzheimer's. © The Author(s) 2014.

  13. The development of automaticity in short-term memory search: Item-response learning and category learning.

    PubMed

    Cao, Rui; Nosofsky, Robert M; Shiffrin, Richard M

    2017-05-01

    In short-term-memory (STM)-search tasks, observers judge whether a test probe was present in a short list of study items. Here we investigated the long-term learning mechanisms that lead to the highly efficient STM-search performance observed under conditions of consistent-mapping (CM) training, in which targets and foils never switch roles across trials. In item-response learning, subjects learn long-term mappings between individual items and target versus foil responses. In category learning, subjects learn high-level codes corresponding to separate sets of items and learn to attach old versus new responses to these category codes. To distinguish between these 2 forms of learning, we tested subjects in categorized varied mapping (CV) conditions: There were 2 distinct categories of items, but the assignment of categories to target versus foil responses varied across trials. In cases involving arbitrary categories, CV performance closely resembled standard varied-mapping performance without categories and departed dramatically from CM performance, supporting the item-response-learning hypothesis. In cases involving prelearned categories, CV performance resembled CM performance, as long as there was sufficient practice or steps taken to reduce trial-to-trial category-switching costs. This pattern of results supports the category-coding hypothesis for sufficiently well-learned categories. Thus, item-response learning occurs rapidly and is used early in CM training; category learning is much slower but is eventually adopted and is used to increase the efficiency of search beyond that available from item-response learning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. 5 CFR 919.900 - Adequate evidence.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Adequate evidence. 919.900 Section 919.900 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS.... Adequate evidence means information sufficient to support the reasonable belief that a particular act or...

  15. 5 CFR 919.900 - Adequate evidence.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Adequate evidence. 919.900 Section 919.900 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS.... Adequate evidence means information sufficient to support the reasonable belief that a particular act or...

  16. 5 CFR 919.900 - Adequate evidence.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Adequate evidence. 919.900 Section 919.900 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS.... Adequate evidence means information sufficient to support the reasonable belief that a particular act or...

  17. 5 CFR 919.900 - Adequate evidence.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Adequate evidence. 919.900 Section 919.900 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS.... Adequate evidence means information sufficient to support the reasonable belief that a particular act or...

  18. 5 CFR 919.900 - Adequate evidence.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Adequate evidence. 919.900 Section 919.900 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS.... Adequate evidence means information sufficient to support the reasonable belief that a particular act or...

  19. 7 CFR 1780.61 - Construction contracts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Construction contracts. 1780.61 Section 1780.61..., Constructing and Inspections § 1780.61 Construction contracts. Contract documents must be sufficiently.... (a) Standard construction contract documents. If the construction contract documents utilized are not...

  20. 7 CFR 1780.61 - Construction contracts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Construction contracts. 1780.61 Section 1780.61..., Constructing and Inspections § 1780.61 Construction contracts. Contract documents must be sufficiently.... (a) Standard construction contract documents. If the construction contract documents utilized are not...

  1. 45 CFR 1336.20 - Program purpose.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Program purpose. 1336.20 Section 1336.20 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES... the goal of economic and social self-sufficiency for Native Americans. ...

  2. 45 CFR 1336.20 - Program purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Program purpose. 1336.20 Section 1336.20 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES... the goal of economic and social self-sufficiency for Native Americans. ...

  3. 45 CFR 1336.20 - Program purpose.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Program purpose. 1336.20 Section 1336.20 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES... the goal of economic and social self-sufficiency for Native Americans. ...

  4. 48 CFR 1349.402-3 - Procedure for default

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedure for default 1349.402-3 Section 1349.402-3 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACT... Executive, and the action has been reviewed for legal sufficiency. ...

  5. 5 CFR 2638.202 - Responsibilities of agency head.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 2638.202 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official... ethics program. He or she shall make available to the ethics program sufficient resources (including...

  6. 10 CFR 35.690 - Training for use of remote afterloader units, teletherapy units, and gamma stereotactic...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... measurement of radioactivity; and (D) Radiation biology; and (ii) 500 hours of work experience, under the... section, and has achieved a level of competency sufficient to function independently as an authorized user...

  7. 5 CFR 2638.202 - Responsibilities of agency head.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Section 2638.202 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official... ethics program. He or she shall make available to the ethics program sufficient resources (including...

  8. 5 CFR 2638.202 - Responsibilities of agency head.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Section 2638.202 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official... ethics program. He or she shall make available to the ethics program sufficient resources (including...

  9. 5 CFR 2638.202 - Responsibilities of agency head.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Section 2638.202 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official... ethics program. He or she shall make available to the ethics program sufficient resources (including...

  10. 76 FR 81922 - Nationwide Categorical Waivers Under Section 1605 (Buy American) of the American Recovery and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... States in sufficient and reasonably available quantities and of a satisfactory quality), with respect to...) Thermostatic Regulator Valves that regulate the flow of hot water or low pressure steam through free-standing...

  11. 20 CFR 437.36 - Procurement.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... resources. (9) Grantees and subgrantees must maintain records sufficient to detail the significant history... section. (e) Contracting with small and minority firms, women's business enterprise and labor surplus area... firms, women's business enterprises, and labor surplus area firms are used when possible. (2...

  12. 20 CFR 437.36 - Procurement.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... resources. (9) Grantees and subgrantees must maintain records sufficient to detail the significant history... section. (e) Contracting with small and minority firms, women's business enterprise and labor surplus area... firms, women's business enterprises, and labor surplus area firms are used when possible. (2...

  13. 20 CFR 437.36 - Procurement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... resources. (9) Grantees and subgrantees must maintain records sufficient to detail the significant history... section. (e) Contracting with small and minority firms, women's business enterprise and labor surplus area... firms, women's business enterprises, and labor surplus area firms are used when possible. (2...

  14. 20 CFR 437.36 - Procurement.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... resources. (9) Grantees and subgrantees must maintain records sufficient to detail the significant history... section. (e) Contracting with small and minority firms, women's business enterprise and labor surplus area... firms, women's business enterprises, and labor surplus area firms are used when possible. (2...

  15. 20 CFR 411.650 - Is there a process for resolving disputes between ENs that are not State VR agencies and PMs...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 411.650 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Ticket to Work Program Dispute Resolution Disputes Between Employment Networks and Program...

  16. 20 CFR 411.650 - Is there a process for resolving disputes between ENs that are not State VR agencies and PMs...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Section 411.650 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Ticket to Work Program Dispute Resolution Disputes Between Employment Networks and Program...

  17. 20 CFR 411.650 - Is there a process for resolving disputes between ENs that are not State VR agencies and PMs...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Section 411.650 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Ticket to Work Program Dispute Resolution Disputes Between Employment Networks and Program...

  18. The transcension hypothesis: Sufficiently advanced civilizations invariably leave our universe, and implications for METI and SETI

    NASA Astrophysics Data System (ADS)

    Smart, John M.

    2012-09-01

    The emerging science of evolutionary developmental ("evo devo") biology can aid us in thinking about our universe as both an evolutionary system, where most processes are unpredictable and creative, and a developmental system, where a special few processes are predictable and constrained to produce far-future-specific emergent order, just as we see in the common developmental processes in two stars of an identical population type, or in two genetically identical twins in biology. The transcension hypothesis proposes that a universal process of evolutionary development guides all sufficiently advanced civilizations into what may be called "inner space," a computationally optimal domain of increasingly dense, productive, miniaturized, and efficient scales of space, time, energy, and matter, and eventually, to a black-hole-like destination. Transcension as a developmental destiny might also contribute to the solution to the Fermi paradox, the question of why we have not seen evidence of or received beacons from intelligent civilizations. A few potential evolutionary, developmental, and information theoretic reasons, mechanisms, and models for constrained transcension of advanced intelligence are briefly considered. In particular, we introduce arguments that black holes may be a developmental destiny and standard attractor for all higher intelligence, as they appear to some to be ideal computing, learning, forward time travel, energy harvesting, civilization merger, natural selection, and universe replication devices. In the transcension hypothesis, simpler civilizations that succeed in resisting transcension by staying in outer (normal) space would be developmental failures, which are statistically very rare late in the life cycle of any biological developing system. If transcension is a developmental process, we may expect brief broadcasts or subtle forms of galactic engineering to occur in small portions of a few galaxies, the handiwork of young and immature civilizations, but constrained transcension should be by far the norm for all mature civilizations. The transcension hypothesis has significant and testable implications for our current and future METI and SETI agendas. If all universal intelligence eventually transcends to black-hole-like environments, after which some form of merger and selection occurs, and if two-way messaging (a send-receive cycle) is severely limited by the great distances between neighboring and rapidly transcending civilizations, then sending one-way METI or probes prior to transcension becomes the only real communication option. But one-way messaging or probes may provably reduce the evolutionary diversity in all civilizations receiving the message, as they would then arrive at their local transcensions in a much more homogenous fashion. If true, an ethical injunction against one-way messaging or probes might emerge in the morality and sustainability systems of all sufficiently advanced civilizations, an argument known as the Zoo hypothesis in Fermi paradox literature, if all higher intelligences are subject to an evolutionary attractor to maximize their local diversity, and a developmental attractor to merge and advance universal intelligence. In any such environment, the evolutionary value of sending any interstellar message or probe may simply not be worth the cost, if transcension is an inevitable, accelerative, and testable developmental process, one that eventually will be discovered and quantitatively described by future physics. Fortunately, transcension processes may be measurable today even without good physical theory, and radio and optical SETI may each provide empirical tests. If transcension is a universal developmental constraint, then without exception all early and low-power electromagnetic leakage signals (radar, radio, television), and later, optical evidence of the exoplanets and their atmospheres should reliably cease as each civilization enters its own technological singularities (emergence of postbiological intelligence and life forms) and recognizes that they are on an optimal and accelerating path to a black-hole-like environment. Furthermore, optical SETI may soon allow us to map an expanding area of the galactic habitable zone we may call the galactic transcension zone, an inner ring that contains older transcended civilizations, and a missing planets problem as we discover that planets with life signatures occur at a much lower frequencies in this inner ring than in the remainder of the habitable zone.

  19. A comparison of digitized frozen section and smear preparations for intraoperative neurotelepathology.

    PubMed

    Gould, Peter V; Saikali, Stephan

    2012-01-01

    Intraoperative consultations in neuropathology are often assessed by smear preparations rather than by frozen sections. Both techniques are standard practice for light microscopic examination on site, but there is little data comparing these techniques in a telepathology setting. Thirty cases of brain tumours submitted for intraoperative consultation at our institution between July and December 2010 were identified in which both frozen section and tissue smear preparations were available for digitization at 20× magnification. Slides were digitized using a Hamamatsu Nanozoomer 2.0 HT whole slide scanner, and resulting digital images were visualized at 1680 × 1050 pixel resolution with NDP. view software. The original intraoperative diagnosis was concordant with the sign out diagnosis in 29/30 cases; one tumeur was initially interpreted as a high grade glioma but proved to be a lymphoma at sign out. Digitized frozen section slides were sufficient for diagnosis at 10× magnification in 27/30 cases. Digitized tissue smears were sufficient for diagnosis at 10× magnification in 28/30 cases. In two cases tumour was present on the tissue smear but not the frozen section (one case of recurrent astrocytoma, one case of meningeal carcinomatosis). In one case of lymphoma, tumour was present on frozen section only. These discrepancies were attributed to tissue sampling rather than image quality. Examination of digitized slides at higher magnfication (20×) permitted confirmation of mitoses and Rosenthal fibers on tissue smear preparations, but did not change the primary diagnosis. Intra-slide variations in tissue thickness on smear preparations led to variable loss of focus in digitized images, but did not affect image quality in thinner areas of the smear or impede diagnosis. Digitized tissue smears are suitable for intraoperative neurotelepathology and provide comparable information to digitized frozen sections at medium power magnification.

  20. 26 CFR 20.6324B-1 - Special lien for additional estate tax attributable to farm, etc., valuation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... difference attributable to such interest (as defined by section 2032A(c)(2)(B)). The term “qualified real... director as sufficient security for the maximum potential liability for additional estate tax with respect...

  1. 26 CFR 20.6324B-1 - Special lien for additional estate tax attributable to farm, etc., valuation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... difference attributable to such interest (as defined by section 2032A(c)(2)(B)). The term “qualified real... director as sufficient security for the maximum potential liability for additional estate tax with respect...

  2. 26 CFR 20.6324B-1 - Special lien for additional estate tax attributable to farm, etc., valuation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... difference attributable to such interest (as defined by section 2032A(c)(2)(B)). The term “qualified real... director as sufficient security for the maximum potential liability for additional estate tax with respect...

  3. 45 CFR 1641.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Definitions. 1641.2 Section 1641.2 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION DEBARMENT, SUSPENSION AND REMOVAL OF RECIPIENT AUDITORS General § 1641.2 Definitions. Adequate evidence means information sufficient...

  4. 32 CFR 637.12 - Legal considerations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Legal considerations. 637.12 Section 637.12... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.12 Legal considerations. (a... of establishing a legal opinion as to whether sufficient credible evidence has been established to...

  5. 32 CFR 637.12 - Legal considerations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Legal considerations. 637.12 Section 637.12... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.12 Legal considerations. (a... of establishing a legal opinion as to whether sufficient credible evidence has been established to...

  6. 32 CFR 637.12 - Legal considerations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Legal considerations. 637.12 Section 637.12... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.12 Legal considerations. (a... of establishing a legal opinion as to whether sufficient credible evidence has been established to...

  7. 32 CFR 637.12 - Legal considerations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Legal considerations. 637.12 Section 637.12... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.12 Legal considerations. (a... of establishing a legal opinion as to whether sufficient credible evidence has been established to...

  8. 32 CFR 637.12 - Legal considerations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Legal considerations. 637.12 Section 637.12... CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.12 Legal considerations. (a... of establishing a legal opinion as to whether sufficient credible evidence has been established to...

  9. 48 CFR 206.303-2 - Content.

    Code of Federal Regulations, 2010 CFR

    2000-10-01

    ... 48 Federal Acquisition Regulations System 3 2000-10-01 2000-10-01 false Content. 206.303-2 Section 206.303-2 Federal Acquisition Regulations System DEPARTMENT OF DEFENSE ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 206.303-2 Content. (a) Include sufficient...

  10. 7 CFR 275.15 - Data management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... management information sources available to: (1) Identify all deficiencies in program operations and systems... deficiency, but after reviewing all available management information sources sufficient information is not... 7 Agriculture 4 2010-01-01 2010-01-01 false Data management. 275.15 Section 275.15 Agriculture...

  11. 36 CFR 1254.26 - What can I take into a research room with me?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... wallet or purse is sufficiently small for purposes of this section. You may take cell phones, pagers, and...) and, for cell phone cameras, in § 1254.70(g). (b) Notes and reference materials. You may take notes...

  12. 77 FR 76211 - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... with my determinations of March 30, 2012, and June 11, 2012, that there is a sufficient supply of... and directed to publish this memorandum in the Federal Register. (Presidential Sig.) THE WHITE HOUSE...

  13. 29 CFR 1471.900 - Adequate evidence.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 4 2011-07-01 2011-07-01 false Adequate evidence. 1471.900 Section 1471.900 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT... information sufficient to support the reasonable belief that a particular act or omission has occurred. ...

  14. 29 CFR 1471.900 - Adequate evidence.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 4 2014-07-01 2014-07-01 false Adequate evidence. 1471.900 Section 1471.900 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT... information sufficient to support the reasonable belief that a particular act or omission has occurred. ...

  15. 29 CFR 1471.900 - Adequate evidence.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 4 2012-07-01 2012-07-01 false Adequate evidence. 1471.900 Section 1471.900 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT... information sufficient to support the reasonable belief that a particular act or omission has occurred. ...

  16. 29 CFR 1471.900 - Adequate evidence.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Adequate evidence. 1471.900 Section 1471.900 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT... information sufficient to support the reasonable belief that a particular act or omission has occurred. ...

  17. 7 CFR 3017.900 - Adequate evidence.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Adequate evidence. 3017.900 Section 3017.900 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER... Adequate evidence. Adequate evidence means information sufficient to support the reasonable belief that a...

  18. 29 CFR 1471.900 - Adequate evidence.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 4 2013-07-01 2013-07-01 false Adequate evidence. 1471.900 Section 1471.900 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE DEBARMENT... information sufficient to support the reasonable belief that a particular act or omission has occurred. ...

  19. 14 CFR 414.7 - Eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Eligibility. 414.7 Section 414.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... or reentry. (c) A safety approval applicant must have sufficient knowledge and expertise to show that...

  20. 14 CFR 414.7 - Eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Eligibility. 414.7 Section 414.7 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... or reentry. (c) A safety approval applicant must have sufficient knowledge and expertise to show that...

  1. 5 CFR 582.203 - Information minimally required to accompany legal process.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... accompany legal process. 582.203 Section 582.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.203 Information minimally required to accompany legal process. (a) Sufficient identifying...

  2. 5 CFR 582.203 - Information minimally required to accompany legal process.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... accompany legal process. 582.203 Section 582.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.203 Information minimally required to accompany legal process. (a) Sufficient identifying...

  3. 5 CFR 582.203 - Information minimally required to accompany legal process.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... accompany legal process. 582.203 Section 582.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.203 Information minimally required to accompany legal process. (a) Sufficient identifying...

  4. 5 CFR 582.203 - Information minimally required to accompany legal process.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... accompany legal process. 582.203 Section 582.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.203 Information minimally required to accompany legal process. (a) Sufficient identifying...

  5. 5 CFR 582.203 - Information minimally required to accompany legal process.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... accompany legal process. 582.203 Section 582.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.203 Information minimally required to accompany legal process. (a) Sufficient identifying...

  6. 36 CFR 1254.26 - What can I take into a research room with me?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wallet or purse is sufficiently small for purposes of this section. You may take cell phones, pagers, and...) and, for cell phone cameras, in § 1254.70(g). (b) Notes and reference materials. You may take notes...

  7. 36 CFR 1254.26 - What can I take into a research room with me?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... wallet or purse is sufficiently small for purposes of this section. You may take cell phones, pagers, and...) and, for cell phone cameras, in § 1254.70(g). (b) Notes and reference materials. You may take notes...

  8. 48 CFR 842.1203 - Processing agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing agreements. 842.1203 Section 842.1203 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT... submit all supporting agreements and documentation to the OGC for review as to legal sufficiency. ...

  9. 46 CFR 45.107 - Strength of hull.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Strength of hull. 45.107 Section 45.107 Shipping COAST... Assignment § 45.107 Strength of hull. The general structural strength of the hull must be sufficient for the... Commandant as possessing adequate strength. ...

  10. 46 CFR 169.317 - Accommodations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Accommodations. 169.317 Section 169.317 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Construction and Arrangement Living Spaces § 169.317 Accommodations. (a) Quarters must have sufficient fresh air...

  11. 46 CFR 169.317 - Accommodations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Accommodations. 169.317 Section 169.317 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Construction and Arrangement Living Spaces § 169.317 Accommodations. (a) Quarters must have sufficient fresh air...

  12. 20 CFR 405.217 - Subpoenas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Subpoenas. 405.217 Section 405.217 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY...) Identify the documents with sufficient detail to find them; (2) State the important facts that the document...

  13. 14 CFR 25.1523 - Minimum flight crew.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Minimum flight crew. 25.1523 Section 25.1523 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... sufficient for safe operation, considering— (a) The workload on individual crewmembers; (b) The accessibility...

  14. 14 CFR 29.1523 - Minimum flight crew.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Minimum flight crew. 29.1523 Section 29.1523 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... sufficient for safe operation, considering— (a) The workload on individual crewmembers; (b) The accessibility...

  15. 14 CFR 29.1523 - Minimum flight crew.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Minimum flight crew. 29.1523 Section 29.1523 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... sufficient for safe operation, considering— (a) The workload on individual crewmembers; (b) The accessibility...

  16. 14 CFR 25.1523 - Minimum flight crew.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Minimum flight crew. 25.1523 Section 25.1523 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... sufficient for safe operation, considering— (a) The workload on individual crewmembers; (b) The accessibility...

  17. 45 CFR 1641.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Definitions. 1641.2 Section 1641.2 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION DEBARMENT, SUSPENSION AND REMOVAL OF RECIPIENT AUDITORS General § 1641.2 Definitions. Adequate evidence means information sufficient...

  18. 48 CFR 14.205 - Presolicitation notices.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Presolicitation notices. 14.205 Section 14.205 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... drawings, plans, and specifications. The return date of the notice must be sufficiently in advance of the...

  19. 48 CFR 14.205 - Presolicitation notices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Presolicitation notices. 14.205 Section 14.205 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... drawings, plans, and specifications. The return date of the notice must be sufficiently in advance of the...

  20. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b) Nuclear...

  1. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b) Nuclear...

  2. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b) Nuclear...

  3. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b) Nuclear...

  4. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b) Nuclear...

  5. 30 CFR 780.22 - Geologic information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the collection and analysis of such data is unnecessary because other equivalent information is... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Geologic information. 780.22 Section 780.22... Geologic information. (a) General. Each application shall include geologic information in sufficient detail...

  6. 20 CFR 411.552 - What effect will the subsequent entitlement to title II benefits have on EN payments for title...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...? 411.552 Section 411.552 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.552 What effect will the subsequent entitlement...

  7. 20 CFR 411.552 - What effect will the subsequent entitlement to title II benefits have on EN payments for title...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...? 411.552 Section 411.552 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.552 What effect will the subsequent entitlement...

  8. 20 CFR 411.552 - What effect will the subsequent entitlement to title II benefits have on EN payments for title...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...? 411.552 Section 411.552 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.552 What effect will the subsequent entitlement...

  9. 20 CFR 411.552 - What effect will the subsequent entitlement to title II benefits have on EN payments for title...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...? 411.552 Section 411.552 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.552 What effect will the subsequent entitlement...

  10. 20 CFR 411.552 - What effect will the subsequent entitlement to title II benefits have on EN payments for title...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...? 411.552 Section 411.552 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.552 What effect will the subsequent entitlement...

  11. 45 CFR 671.6 - Applications for permits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Applications for permits. 671.6 Section 671.6 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE... Science Foundation, 4201 Wilson Boulevard, Arlington, VA 22230. (c) Sufficiency of application. The...

  12. [Incidence of fetal macrosomia: maternal and fetal morbidity].

    PubMed

    Rodríguez-Rojas, R R; Cantú-Esquivel, M G; Benavides-de la Garza, L; Benavides-de Anda, L

    1996-06-01

    The macrosomia is an obstetric eventuality associated to high maternal-fetal morbidity-mortality. This assay was planned in order to know the incidence of macrosomia in our institution, the relation between vaginal and abdominal deliveries and the fetal-maternal morbidity we reviewed 3590 records and we found 5.6% incidence of macrosomia in the global obstetric population. There was 58% of vaginal deliveries, 68% of the newborn were male. The main complications were in the C. sections, 2 laceration of the hysterectomy, and 2 peroperative atonias. In the vaginal deliveries, the lacerations of III and IV grade were 9 of each grade. The main fetal complications were 5 slight to severe asphyxia and 4 shoulder dystocias. This assay concludes that the macrosomia in our service is similar to the already published ones, a 42% were C. section and the maternal-fetal morbidity was low.

  13. Microtubules soften due to cross-sectional flattening

    DOE PAGES

    Memet, Edvin; Hilitsk, Feodor; Morris, Margaret A.; ...

    2018-06-01

    We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied strains. We find that, while in the low-strain regime, microtubules may be quantitatively described in terms of the classical Euler-Bernoulli elastic filament, above a critical strain they deviate from this simple elastic model, showing a softening response with increasing deformations. A three-dimensional thin-shell model, in which the increased mechanical compliance is caused by flattening and eventual buckling of the filament cross-section, captures this softening effectmore » in the high strain regime and yields quantitative values of the effective mechanical properties of microtubules. Our results demonstrate that properties of microtubules are highly dependent on the magnitude of the applied strain and offer a new interpretation for the large variety in microtubule mechanical data measured by different methods.« less

  14. Microtubules soften due to cross-sectional flattening

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Memet, Edvin; Hilitsk, Feodor; Morris, Margaret A.

    We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied strains. We find that, while in the low-strain regime, microtubules may be quantitatively described in terms of the classical Euler-Bernoulli elastic filament, above a critical strain they deviate from this simple elastic model, showing a softening response with increasing deformations. A three-dimensional thin-shell model, in which the increased mechanical compliance is caused by flattening and eventual buckling of the filament cross-section, captures this softening effectmore » in the high strain regime and yields quantitative values of the effective mechanical properties of microtubules. Our results demonstrate that properties of microtubules are highly dependent on the magnitude of the applied strain and offer a new interpretation for the large variety in microtubule mechanical data measured by different methods.« less

  15. Experimental investigation of the effect orifice shape and fluid pressure has on high aspect ratio cross-sectional jet behaviour.

    PubMed

    Wakes, S J; Holdø, A E; Meares, A J

    2002-01-04

    Prevention of major disasters such as Piper Alpha is a concern of oil and gas companies when commissioning a new offshore superstructure. Safety studies are undertaken to identify potential major hazards, risks to personnel and that sufficient precautions have been employed to minimise these. Such an assessment will also include the consideration of the protection from gas leaks such as the optimum positions of gas leak detectors and startup safety procedures after a leak. This requires a comprehensive knowledge of the behaviour of the leaking hydrocarbons as they emerge from the leak into the area of concern. Such leaks are most likely to emanate from a high aspect ratio cross-sectional curved slot in a pipeline. This paper challenges the conventional view that it is sufficient to model such leaks as axisymmetric jets. This paper is therefore concerned with an experimental study carried out on a series of more realistic high aspect ratio cross-sectional jets issuing from a flange orifice. Both high quality photographs in both planes of the jets and some quantitative pressure data is examined for a high aspect ratio cross-sectional jet of air at pressures up to 4.136bar. The effect of changing aspect ratio, fluid pressure and orifice shape will be discussed and put into context with regard to how this relates to offshore analysis studies.

  16. The rabbit costal cartilage reconstructive surgical model.

    PubMed

    Badran, Karam W; Waki, Curt; Hamamoto, Ashley; Manz, Ryan; Wong, Brian J F

    2014-02-01

    Rib grafts in facial plastic surgery are becoming more frequently used. Small animal models, although not ideal may be used to emulate costal cartilage-based procedures. A surgical characterization of this tissue will assist future research in the selection of appropriate costal segments, based on quantitative and qualitative properties. The objective of this study is to assess the surgical anatomy of the rabbit costal margin and evaluate costal cartilage for use in either in vivo or ex vivo studies and to examine reconstructive procedures. Detailed thoracic dissections of 21 New Zealand white rabbits were performed post-mortem. Costal cartilage of true, false, and floating ribs were harvested. The length, thickness, and width at proximal, medial, and distal locations of the cartilage, with perichondrium intact were measured. Further qualitative observation and digital images of curvature, flexibility, and segmental cross-sectional shape were recorded. The main outcome measure(s) is to characterize, describe, and assess the consistency of dimensions, location, and shape of costal cartilage. In this study, 12 to 13 ribs encase the thoracic cavity. Cartilage from true ribs has an average length, width, and depth of 23.75 ± 0.662, 3.02 ± 0.025, and 2.18 ± 0.018 mm, respectively. The cartilage from false ribs has an average length, width, and depth of 41.97 ± 1.48, 2.00 ± 0.07, 1.19 ± 0.03 mm, and that of floating ribs are 7.66 ± 0.29, 1.98 ± 0.04, and 0.96 ± 0.03 mm. Rib 8 is found to be the longest costal cartilage (49.10 ± 0.64 mm), with the widest and thickest at ribs 1 (3.91 ± 0.08 mm) and 6 (2.41 ± 0.11 mm), respectively. Cross-sectional segments reveal the distal cartilage to maintain an hourglass shape that broadens to become circular and eventually ovoid at the costochondral junction. The New Zealand white rabbit is a practical source of costal cartilage that is of sufficient size and reproducibility to use in surgical research where the long-term effects of operations, therapies, devices, and pharmacologic on cartilage can be studied in vivo. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  17. 30 CFR 57.12004 - Electrical conductors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electrical conductors. 57.12004 Section 57... Surface and Underground § 57.12004 Electrical conductors. Electrical conductors shall be of a sufficient... operations will not damage the insulating materials. Electrical conductors exposed to mechanical damage shall...

  18. 34 CFR 200.28 - Schoolwide program components.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... provide information on, and to improve, the achievement of individual students and the overall... literacy services, to increase parental involvement in accordance with sections 1118(c) through (f) and... identified on a timely basis; and (2) Provide sufficient information on which to base effective assistance to...

  19. 40 CFR 63.703 - Standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... gaseous HAP emitted from each solvent storage tank, piece of mix preparation equipment, coating operation..., piece of mix preparation equipment, coating operation, waste handling device, and condenser vent in... of this method is sufficient to meet the requirements of paragraph (c)(1) or (2) of this section. (4...

  20. 10 CFR 34.25 - Radiation survey instruments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Radiation survey instruments. 34.25 Section 34.25 Energy... INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.25 Radiation survey instruments. (a) The licensee shall keep sufficient calibrated and operable radiation survey instruments at each location where radioactive...

  1. 10 CFR 34.25 - Radiation survey instruments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Radiation survey instruments. 34.25 Section 34.25 Energy... INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.25 Radiation survey instruments. (a) The licensee shall keep sufficient calibrated and operable radiation survey instruments at each location where radioactive...

  2. 10 CFR 34.25 - Radiation survey instruments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Radiation survey instruments. 34.25 Section 34.25 Energy... INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.25 Radiation survey instruments. (a) The licensee shall keep sufficient calibrated and operable radiation survey instruments at each location where radioactive...

  3. 10 CFR 34.25 - Radiation survey instruments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Radiation survey instruments. 34.25 Section 34.25 Energy... INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.25 Radiation survey instruments. (a) The licensee shall keep sufficient calibrated and operable radiation survey instruments at each location where radioactive...

  4. 30 CFR 784.22 - Geologic information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Geologic information. 784.22 Section 784.22... Geologic information. (a) General. Each application shall include geologic information in sufficient detail...; and (4) Preparing the subsidence control plan under § 784.20. (b) Geologic information shall include...

  5. 30 CFR 784.22 - Geologic information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Geologic information. 784.22 Section 784.22... Geologic information. (a) General. Each application shall include geologic information in sufficient detail...; and (4) Preparing the subsidence control plan under § 784.20. (b) Geologic information shall include...

  6. 48 CFR 701.470 - Procedure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... containing the information listed in paragraph (c) of this section shall be submitted sufficiently in advance... historical data which will contribute to a more complete understanding of the deviation. The comments of the... the regulation being deviated from, an indication as to whether any identical or similar deviations...

  7. 29 CFR 98.900 - Adequate evidence.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Adequate evidence. 98.900 Section 98.900 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 98.900 Adequate evidence. Adequate evidence means information sufficient to support the reasonable belief that a...

  8. 41 CFR 105-68.900 - Adequate evidence.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Adequate evidence. 105-68.900 Section 105-68.900 Public Contracts and Property Management Federal Property Management... evidence. Adequate evidence means information sufficient to support the reasonable belief that a particular...

  9. 41 CFR 105-68.900 - Adequate evidence.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Adequate evidence. 105-68.900 Section 105-68.900 Public Contracts and Property Management Federal Property Management... evidence. Adequate evidence means information sufficient to support the reasonable belief that a particular...

  10. 29 CFR 98.900 - Adequate evidence.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Adequate evidence. 98.900 Section 98.900 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 98.900 Adequate evidence. Adequate evidence means information sufficient to support the reasonable belief that a...

  11. 41 CFR 105-68.900 - Adequate evidence.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Adequate evidence. 105-68.900 Section 105-68.900 Public Contracts and Property Management Federal Property Management... evidence. Adequate evidence means information sufficient to support the reasonable belief that a particular...

  12. 41 CFR 105-68.900 - Adequate evidence.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Adequate evidence. 105-68.900 Section 105-68.900 Public Contracts and Property Management Federal Property Management... evidence. Adequate evidence means information sufficient to support the reasonable belief that a particular...

  13. 41 CFR 105-68.900 - Adequate evidence.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Adequate evidence. 105-68.900 Section 105-68.900 Public Contracts and Property Management Federal Property Management... evidence. Adequate evidence means information sufficient to support the reasonable belief that a particular...

  14. 29 CFR 98.900 - Adequate evidence.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Adequate evidence. 98.900 Section 98.900 Labor Office of the Secretary of Labor GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 98.900 Adequate evidence. Adequate evidence means information sufficient to support the reasonable belief that a...

  15. 14 CFR 145.151 - Personnel requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Personnel requirements. 145.151 Section 145.151 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... specifications; (c) Ensure it has a sufficient number of employees with the training or knowledge and experience...

  16. 14 CFR 145.151 - Personnel requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Personnel requirements. 145.151 Section 145.151 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... specifications; (c) Ensure it has a sufficient number of employees with the training or knowledge and experience...

  17. 36 CFR § 1254.26 - What can I take into a research room with me?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... wallet or purse is sufficiently small for purposes of this section. You may take cell phones, pagers, and...) and, for cell phone cameras, in § 1254.70(g). (b) Notes and reference materials. You may take notes...

  18. 30 CFR 57.12004 - Electrical conductors.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electrical conductors. 57.12004 Section 57... Surface and Underground § 57.12004 Electrical conductors. Electrical conductors shall be of a sufficient... operations will not damage the insulating materials. Electrical conductors exposed to mechanical damage shall...

  19. 30 CFR 57.12004 - Electrical conductors.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electrical conductors. 57.12004 Section 57... Surface and Underground § 57.12004 Electrical conductors. Electrical conductors shall be of a sufficient... operations will not damage the insulating materials. Electrical conductors exposed to mechanical damage shall...

  20. 46 CFR 183.350 - Batteries-general.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Batteries-general. 183.350 Section 183.350 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.350 Batteries—general. (a) Where provisions are made for charging batteries, there must be natural or induced ventilation sufficient to...

  1. 25 CFR 26.23 - What is an Individual Self-Sufficiency Plan (ISP)?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Section 26.23 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT... includes needed finances, special clothing, transportation, and support services necessary for employment; (3) Identifies all financial resources and defines the employment or training objective and...

  2. 10 CFR 51.45 - Environmental report.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the proposal and the alternatives should be presented in comparative form; (4) The relationship... 10 Energy 2 2014-01-01 2014-01-01 false Environmental report. 51.45 Section 51.45 Energy NUCLEAR...; (3) Alternatives to the proposed action. The discussion of alternatives shall be sufficiently...

  3. 10 CFR 20.1905 - Exemptions to labeling requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Exemptions to labeling requirements. 20.1905 Section 20.1905 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Precautionary... have sufficient instruction to minimize radiation exposure while handling or working in the vicinity of...

  4. 10 CFR 20.1905 - Exemptions to labeling requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Exemptions to labeling requirements. 20.1905 Section 20.1905 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Precautionary... have sufficient instruction to minimize radiation exposure while handling or working in the vicinity of...

  5. 10 CFR 20.1905 - Exemptions to labeling requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Exemptions to labeling requirements. 20.1905 Section 20.1905 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Precautionary... have sufficient instruction to minimize radiation exposure while handling or working in the vicinity of...

  6. 10 CFR 20.1905 - Exemptions to labeling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Exemptions to labeling requirements. 20.1905 Section 20.1905 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Precautionary... have sufficient instruction to minimize radiation exposure while handling or working in the vicinity of...

  7. 10 CFR 20.1905 - Exemptions to labeling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Exemptions to labeling requirements. 20.1905 Section 20.1905 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Precautionary... have sufficient instruction to minimize radiation exposure while handling or working in the vicinity of...

  8. 25 CFR 515.9 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Fees. 515.9 Section 515.9 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS PRIVACY ACT PROCEDURES § 515.9 Fees. The Commission... Commission may charge a fee sufficient to cover the cost of duplication. ...

  9. 46 CFR 183.350 - Batteries-general.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Batteries-general. 183.350 Section 183.350 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.350 Batteries—general. (a) Where provisions are made for charging batteries, there must be natural or induced ventilation sufficient to...

  10. 46 CFR 183.350 - Batteries-general.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Batteries-general. 183.350 Section 183.350 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.350 Batteries—general. (a) Where provisions are made for charging batteries, there must be natural or induced ventilation sufficient to...

  11. 46 CFR 183.350 - Batteries-general.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Batteries-general. 183.350 Section 183.350 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.350 Batteries—general. (a) Where provisions are made for charging batteries, there must be natural or induced ventilation sufficient to...

  12. 46 CFR 183.350 - Batteries-general.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Batteries-general. 183.350 Section 183.350 Shipping...) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.350 Batteries—general. (a) Where provisions are made for charging batteries, there must be natural or induced ventilation sufficient to...

  13. 28 CFR 42.414 - Federal agency staff.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Federal agency staff. 42.414 Section 42.414 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY... § 42.414 Federal agency staff. Sufficient personnel shall be assigned by a federal agency to its title...

  14. 28 CFR 42.414 - Federal agency staff.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Federal agency staff. 42.414 Section 42.414 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY... § 42.414 Federal agency staff. Sufficient personnel shall be assigned by a federal agency to its title...

  15. 28 CFR 42.414 - Federal agency staff.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Federal agency staff. 42.414 Section 42.414 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY... § 42.414 Federal agency staff. Sufficient personnel shall be assigned by a federal agency to its title...

  16. 28 CFR 42.414 - Federal agency staff.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Federal agency staff. 42.414 Section 42.414 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY... § 42.414 Federal agency staff. Sufficient personnel shall be assigned by a federal agency to its title...

  17. 28 CFR 42.414 - Federal agency staff.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Federal agency staff. 42.414 Section 42.414 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY... § 42.414 Federal agency staff. Sufficient personnel shall be assigned by a federal agency to its title...

  18. 20 CFR 628.205 - Governor's coordination and special services plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Job Opportunities and Basic Skills (JOBS) program; the certification of the implementation of the... performance; program administration; program financial management and audit resolution procedures; capacity... information described in paragraph (c)(1) of this section shall be provided to SDA's in sufficient time for...

  19. 21 CFR 137.180 - Self-rising flour.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... acid-reacting substances monocalcium phosphate, sodium acid pyrophosphate, and sodium aluminum... section not less than 0.5 percent of carbon dioxide is evolved. The acid-reacting substance is added in sufficient quantity to neutralize the sodium bicarbonate. The combined weight of such acid-reacting substance...

  20. 21 CFR 137.180 - Self-rising flour.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... acid-reacting substances monocalcium phosphate, sodium acid pyrophosphate, and sodium aluminum... section not less than 0.5 percent of carbon dioxide is evolved. The acid-reacting substance is added in sufficient quantity to neutralize the sodium bicarbonate. The combined weight of such acid-reacting substance...

  1. 21 CFR 137.180 - Self-rising flour.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... acid-reacting substances monocalcium phosphate, sodium acid pyrophosphate, and sodium aluminum... section not less than 0.5 percent of carbon dioxide is evolved. The acid-reacting substance is added in sufficient quantity to neutralize the sodium bicarbonate. The combined weight of such acid-reacting substance...

  2. 21 CFR 137.180 - Self-rising flour.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... acid-reacting substances monocalcium phosphate, sodium acid pyrophosphate, and sodium aluminum... section not less than 0.5 percent of carbon dioxide is evolved. The acid-reacting substance is added in sufficient quantity to neutralize the sodium bicarbonate. The combined weight of such acid-reacting substance...

  3. 34 CFR 200.28 - Schoolwide program components.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... provide information on, and to improve, the achievement of individual students and the overall... literacy services, to increase parental involvement in accordance with sections 1118(c) through (f) and... identified on a timely basis; and (2) Provide sufficient information on which to base effective assistance to...

  4. 34 CFR 200.28 - Schoolwide program components.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... provide information on, and to improve, the achievement of individual students and the overall... literacy services, to increase parental involvement in accordance with sections 1118(c) through (f) and... identified on a timely basis; and (2) Provide sufficient information on which to base effective assistance to...

  5. 34 CFR 200.28 - Schoolwide program components.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... provide information on, and to improve, the achievement of individual students and the overall... literacy services, to increase parental involvement in accordance with sections 1118(c) through (f) and... identified on a timely basis; and (2) Provide sufficient information on which to base effective assistance to...

  6. 34 CFR 200.28 - Schoolwide program components.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... provide information on, and to improve, the achievement of individual students and the overall... literacy services, to increase parental involvement in accordance with sections 1118(c) through (f) and... identified on a timely basis; and (2) Provide sufficient information on which to base effective assistance to...

  7. 10 CFR 61.15 - Financial information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Financial information. 61.15 Section 61.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.15 Financial information. The financial information must be sufficient to demonstrate that the...

  8. 10 CFR 61.15 - Financial information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Financial information. 61.15 Section 61.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.15 Financial information. The financial information must be sufficient to demonstrate that the...

  9. 10 CFR 61.15 - Financial information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Financial information. 61.15 Section 61.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.15 Financial information. The financial information must be sufficient to demonstrate that the...

  10. 10 CFR 61.15 - Financial information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Financial information. 61.15 Section 61.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.15 Financial information. The financial information must be sufficient to demonstrate that the...

  11. 10 CFR 61.15 - Financial information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Financial information. 61.15 Section 61.15 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.15 Financial information. The financial information must be sufficient to demonstrate that the...

  12. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other device...

  13. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other device...

  14. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other device...

  15. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other device...

  16. 14 CFR 25.1381 - Instrument lights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Instrument lights. 25.1381 Section 25.1381... STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Lights § 25.1381 Instrument lights. (a) The instrument lights must— (1) Provide sufficient illumination to make each instrument, switch and other device...

  17. Experiments with the Dragon Machine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R.E. Malenfant

    2005-08-12

    The basic characteristics of a self-sustaining chain reaction were demonstrated with the Chicago Pile in 1943, but it was not until early 1945 that sufficient enriched material became available to experimentally verify fast-neutron cross-sections and the kinetic characteristics of a nuclear chain reaction sustained with prompt neutrons alone. However, the demands of wartime and the rapid decline in effort following the cessation of hostilities often resulted in the failure to fully document the experiments or in the loss of documentation as personnel returned to civilian pursuits. When documented, the results were often highly classified. Even when eventually declassified, the datamore » were often not approved for public release until years later.2 Even after declassification and approval for public release, the records are sometimes difficult to find. Through a fortuitous discovery, a set of handwritten notes by ''ORF July 1945'' entitled ''Dragon - Research with a Pulsed Fission Reactor'' was found by William L. Myers in an old storage safe at Pajarito Site of the Los Alamos National Laboratory3. Of course, ORF was identified as Otto R. Frisch. The document was attached to a page in a nondescript spiral bound notebook labeled ''494 Book'' that bore the signatures of Louis Slotin and P. Morrison. The notes also reference an ''Idea LS'' that can only be Louis Slotin. The discovery of the notes led to a search of Laboratory Archives, the negative files of the photo lab, and the Report Library for additional details of the experiments with the Dragon machine that were conducted between January and July 1945. The assembly machine and the experiments were carefully conceived and skillfully executed. The analyses--without the crutch of computers--display real insight into the characteristics of the nuclear chain reaction. The information presented here provides what is believed to be a complete collection of the original documentation of the observations made with the Dragon Machine in early 1945.« less

  18. Characteristics, Quality and Contribution to Signal Detection of Spontaneous Reports of Adverse Drug Reactions Via the WEB-RADR Mobile Application: A Descriptive Cross-Sectional Study.

    PubMed

    Oosterhuis, Ingrid; Taavola, Henric; Tregunno, Philip M; Mas, Petar; Gama, Sara; Newbould, Victoria; Caster, Ola; Härmark, Linda

    2018-05-14

    Spontaneous reporting of suspected adverse drug reactions is key for efficient post-marketing safety surveillance. To increase usability and accessibility of reporting tools, the Web-Recognising Adverse Drug Reactions (WEB-RADR) consortium developed a smartphone application (app) based on a simplified reporting form. The objective of this study was to evaluate the characteristics, quality and contribution to signals of reports submitted via the WEB-RADR app. The app was launched in the UK, the Netherlands and Croatia between July 2015 and May 2016. Spontaneous reports submitted until September 2016 with a single reporter were included. For each country, app reports and reports received through conventional means in the same time period were compared to identify characteristic features. A random subset of reports was assessed for clinical quality and completeness. The contribution to signal detection was assessed by a descriptive analysis. Higher proportions of app reports were submitted by patients in the UK (28 vs. 18%) and Croatia (32 vs. 7%); both p < 0.01. In the Netherlands, the difference was small (60 vs. 57%; p = 0.5). The proportion of female patients and the median patient ages in app reports submitted by patients were similar to the reference. The proportion of reports of at least moderate quality was high in both samples (app: 78-85%, reference: 78-98%), for all countries. App reports contributed to detecting eight potential safety signals at the national level, four of which were eventually signalled. The WEB-RADR app offers a new route of spontaneous reporting that shows promise in attracting reports from patients and that could become an important tool in the future. Patient demographics are similar to conventional routes, report quality is sufficient despite a simplified reporting form, and app reports show potential in contributing to signal detection.

  19. Potential of Higher Moments of the Radar Doppler Spectrum for Studying Ice Clouds

    NASA Astrophysics Data System (ADS)

    Loehnert, U.; Maahn, M.

    2015-12-01

    More observations of ice clouds are required to fill gaps in understanding of microphysical properties and processes. However, in situ observations by aircraft are costly and cannot provide long term observations which are required for a deeper understanding of the processes. Ground based remote sensing observations have the potential to fill this gap, but their observations do not contain sufficient information to unambiguously constrain ice cloud properties which leads to high uncertainties. For vertically pointing cloud radars, usually only reflectivity and mean Doppler velocity are used for retrievals; some studies proposed also the use of Doppler spectrum width.In this study, it is investigated whether additional information can be obtained by exploiting also higher moments of the Doppler spectrum such as skewness and kurtosis together with the slope of the Doppler peak. For this, observations of pure ice clouds from the Indirect and Semi-Direct Aerosol Campaign (ISDAC) in Alaska 2008 are analyzed. Using the ISDAC data set, an Optimal Estimation based retrieval is set up based on synthetic and real radar observations. The passive and active microwave radiative transfer model (PAMTRA) is used as a forward model together with the Self-Similar Rayleigh-Gans approximation for estimation of the scattering properties. The state vector of the retrieval consists of the parameters required to simulate the radar Doppler spectrum and describes particle mass, cross section area, particle size distribution, and kinematic conditions such as turbulence and vertical air motion. Using the retrieval, the information content (degrees of freedom for signal) is quantified that higher moments and slopes can contribute to an ice cloud retrieval. The impact of multiple frequencies, radar sensitivity and radar calibration is studied. For example, it is found that a single-frequency measurement using all moments and slopes contains already more information content than a dual-frequency measurement using only reflectivity and mean Doppler velocity. Eventually, the errors and uncertainties of the retrieved ice cloud parameters are investigated for the various retrieval configurations.

  20. Potential of Higher Moments of the Radar Doppler Spectrum for Studying Ice Clouds

    NASA Astrophysics Data System (ADS)

    Lunt, M. F.; Rigby, M. L.; Ganesan, A.; Manning, A.; O'Doherty, S.; Prinn, R. G.; Saito, T.; Harth, C. M.; Muhle, J.; Weiss, R. F.; Salameh, P.; Arnold, T.; Yokouchi, Y.; Krummel, P. B.; Steele, P.; Fraser, P. J.; Li, S.; Park, S.; Kim, J.; Reimann, S.; Vollmer, M. K.; Lunder, C. R.; Hermansen, O.; Schmidbauer, N.; Young, D.; Simmonds, P. G.

    2014-12-01

    More observations of ice clouds are required to fill gaps in understanding of microphysical properties and processes. However, in situ observations by aircraft are costly and cannot provide long term observations which are required for a deeper understanding of the processes. Ground based remote sensing observations have the potential to fill this gap, but their observations do not contain sufficient information to unambiguously constrain ice cloud properties which leads to high uncertainties. For vertically pointing cloud radars, usually only reflectivity and mean Doppler velocity are used for retrievals; some studies proposed also the use of Doppler spectrum width.In this study, it is investigated whether additional information can be obtained by exploiting also higher moments of the Doppler spectrum such as skewness and kurtosis together with the slope of the Doppler peak. For this, observations of pure ice clouds from the Indirect and Semi-Direct Aerosol Campaign (ISDAC) in Alaska 2008 are analyzed. Using the ISDAC data set, an Optimal Estimation based retrieval is set up based on synthetic and real radar observations. The passive and active microwave radiative transfer model (PAMTRA) is used as a forward model together with the Self-Similar Rayleigh-Gans approximation for estimation of the scattering properties. The state vector of the retrieval consists of the parameters required to simulate the radar Doppler spectrum and describes particle mass, cross section area, particle size distribution, and kinematic conditions such as turbulence and vertical air motion. Using the retrieval, the information content (degrees of freedom for signal) is quantified that higher moments and slopes can contribute to an ice cloud retrieval. The impact of multiple frequencies, radar sensitivity and radar calibration is studied. For example, it is found that a single-frequency measurement using all moments and slopes contains already more information content than a dual-frequency measurement using only reflectivity and mean Doppler velocity. Eventually, the errors and uncertainties of the retrieved ice cloud parameters are investigated for the various retrieval configurations.

  1. Bifurcation and stability of single and multiple vortex rings in three-dimensional Bose-Einstein condensates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bisset, R. N.; Wang, Wenlong; Ticknor, C.

    Here, we investigate how single- and multi-vortex-ring states can emerge from a planar dark soliton in three-dimensional (3D) Bose-Einstein condensates (confined in isotropic or anisotropic traps) through bifurcations. We characterize such bifurcations quantitatively using a Galerkin-type approach and find good qualitative and quantitative agreement with our Bogoliubov–de Gennes (BdG) analysis. We also systematically characterize the BdG spectrum of the dark solitons, using perturbation theory, and obtain a quantitative match with our 3D BdG numerical calculations. We then turn our attention to the emergence of single- and multi-vortex-ring states. We systematically capture these as stationary states of the system and quantifymore » their BdG spectra numerically. We found that although the vortex ring may be unstable when bifurcating, its instabilities weaken and may even eventually disappear for sufficiently large chemical potentials and suitable trap settings. For instance, we demonstrate the stability of the vortex ring for an isotropic trap in the large-chemical-potential regime.« less

  2. An analytic resolution to the competition between Lyman-Werner radiation and metal winds in direct collapse black hole hosts

    NASA Astrophysics Data System (ADS)

    Agarwal, Bhaskar; Regan, John; Klessen, Ralf S.; Downes, Turlough P.; Zackrisson, Erik

    2017-10-01

    A near pristine atomic cooling halo close to a star forming galaxy offers a natural pathway for forming massive direct collapse black hole (DCBH) seeds, which could be the progenitors of the z > 6 redshift quasars. The close proximity of the haloes enables a sufficient Lyman-Werner flux to effectively dissociate H2 in the core of the atomic cooling halo. A mild background may also be required to delay star formation in the atomic cooling halo, often attributed to distant background galaxies. In this paper, we investigate the impact of metal pollution from both the background galaxies and the close star forming galaxy under extremely unfavourable conditions such as instantaneous metal mixing. We find that within the time window of DCBH formation, the level of pollution never exceeds the critical threshold (Zcr ˜ 1 × 10-5 Z⊙) and attains a maximum metallicity of Z ˜ 2 × 10- 6 Z⊙. As the system evolves, the metallicity eventually exceeds the critical threshold, long after the DCBH has formed.

  3. Electrolytic pretreatment unit gaseous effluent conditioning

    NASA Technical Reports Server (NTRS)

    Colombo, G. V.; Putnam, D. F.

    1976-01-01

    The electrolytic pretreatment of urine is an advanced process that eliminates the need for handling and storing the highly corrosive chemicals that are normally used in water reclamation systems. The electrolytic pretreatment process also converts the organic materials in urine to gases (N2 and O2) that can be used to replenish those lost to space by leakage, venting, and air lock operations. The electrolytic process is more than a pretreatment, since it decreases the urine solids content by approximately one third, thus reducing the load and eventual solids storage requirements of the urine processing system. The evolved gases from the pretreatment step cannot, however, be returned directly to the atmosphere of a spacecraft without first removing several impurities including hydrogen, chlorine, and certain organic compounds. A treatment concept was developed that would decrease the impurities in the gas stream that emanates from an electrolysis unit to levels sufficiently low to allow the conditioned gas stream to be safely discharged to a spacecraft atmosphere. Two methods were experimentally demonstrated that can accomplish the desired cleanup. The bases of the two methods are, repectively: (1) raw urine scrubbing and (2) silica gel sorption.

  4. Analysis of Current-mode Detectors For Resonance Detection In Neutron Optics Time Reversal Symmetry Experiment

    NASA Astrophysics Data System (ADS)

    Forbes, Grant; Noptrex Collaboration

    2017-09-01

    One of the most promising explanations for the observed matter-antimatter asymmetry in our universe is the search for new sources of time-reversal (T) symmetry violation. The current amount of violation seen in the kaon and B-meson systems is not sufficient to describe this asymmetry. The Neutron Optics Time Reversal Experiment Collaboration (NOPTREX) is a null test for T violation in polarized neutron transmission through a polarized 139La target. Due to the high neutron flux needed for this experiment, as well as the ability to effectively subtract background noise, a current-mode neutron detector that can resolve resonances at epithermal energies has been proposed. In order to ascertain if this detector design would meet the requirements for the eventual NOPTREX experiment, prototypical detectors were tested at the NOBORU beam at the Japan Proton Accelerator Research Complex (JPARC) facility. Resonances in In and Ta were measured and the collected data was analyzed. This presentation will describe the analysis process and the efficacy of the detectors will be discussed. Department of Energy under Contract DE-SC0008107, UGRAS Scholarship.

  5. Nanoparticles Containing Curcumin Useful for Suppressing Macrophages In Vivo in Mice

    PubMed Central

    Amano, Chie; Minematsu, Hideki; Fujita, Kazuyo; Iwashita, Shinki; Adachi, Masaki; Igarashi, Koichi; Hinuma, Shuji

    2015-01-01

    To explore a novel method using liposomes to suppress macrophages, we screened food constituents through cell culture assays. Curcumin was one of the strongest compounds exhibiting suppressive effects on macrophages. We subsequently tried various methods to prepare liposomal curcumin, and eventually succeeded in preparing liposomes with sufficient amounts of curcumin to suppress macrophages by incorporating a complex of curcumin and bovine serum albumin. The diameter of the resultant nanoparticles, the liposomes containing curcumin, ranged from 60 to 100 nm. Flow cytometric analyses revealed that after intraperitoneal administration of the liposomes containing curcumin into mice, these were incorporated mainly by macrophages positive for F4/80, CD36, and CD11b antigens. Peritoneal cells prepared from mice injected in vivo with the liposomes containing curcumin apparently decreased interleukin-6-producing activities. Major changes in body weight and survival rates in the mice were not observed after administrating the liposomes containing curcumin. These results indicate that the liposomes containing curcumin are safe and useful for the selective suppression of macrophages in vivo in mice. PMID:26361331

  6. The maximum drag reduction asymptote

    NASA Astrophysics Data System (ADS)

    Choueiri, George H.; Hof, Bjorn

    2015-11-01

    Addition of long chain polymers is one of the most efficient ways to reduce the drag of turbulent flows. Already very low concentration of polymers can lead to a substantial drag and upon further increase of the concentration the drag reduces until it reaches an empirically found limit, the so called maximum drag reduction (MDR) asymptote, which is independent of the type of polymer used. We here carry out a detailed experimental study of the approach to this asymptote for pipe flow. Particular attention is paid to the recently observed state of elasto-inertial turbulence (EIT) which has been reported to occur in polymer solutions at sufficiently high shear. Our results show that upon the approach to MDR Newtonian turbulence becomes marginalized (hibernation) and eventually completely disappears and is replaced by EIT. In particular, spectra of high Reynolds number MDR flows are compared to flows at high shear rates in small diameter tubes where EIT is found at Re < 100. The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n° [291734].

  7. Comparison of one- and two-photon optical beam-induced current imaging

    NASA Astrophysics Data System (ADS)

    Xu, Chris; Denk, Winfried

    1999-08-01

    Optical beam induced current (OBIC) imaging through the backside of integrated circuits was investigated in the wavelength λ region from 1.15 to 1.26 μm. With a subpicosecond excitation source and approximately 1 mW at the sample, the two-photon contribution to the generated photocurrent dominates at λ=1.25 μm but becomes negligible for λ<1.18 μm. One-photon- (1P-) and two-photon- (2P-) OBIC images are very different. In the 1P case a strong contribution by scattered light to the carrier generation leads to an edge enhancement effect that is entirely missing when 2P excitation dominates. 2P-OBIC images often show supply-voltage dependent intensity steps that are much sharper than the optical resolution permits. The advantages of 2P-OBIC lie in the spatial confinement of the free carrier generation, a more relevant contrast mechanism, and the promise of a substantial increase in spatial resolution because of the quadratic intensity dependence and the possibility of using silicon solid immersion lenses, which could eventually provide resolution sufficient for circuits made by deep UV lithography.

  8. Utility of Amplatzer Vascular Plug with Preoperative Common Hepatic Artery Embolization for Distal Pancreatectomy with En Bloc Celiac Axis Resection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Toguchi, Masafumi, E-mail: e024163@yahoo.co.jp; Tsurusaki, Masakatsu; Numoto, Isao

    PurposeTo evaluate the feasibility and safety of the Amplatzer vascular plug (AVP) for preoperative common hepatic embolization (CHA) before distal pancreatectomy with en bloc celiac axis resection (DP-CAR) to redistribute blood flow to the stomach and liver via the superior mesenteric artery (SMA).Materials and MethodsFour patients (3 males, 1 female; median age 69 years) with locally advanced pancreatic body cancer underwent preoperative CHA embolization with AVP. After embolization, SMA arteriography was performed to confirm the alteration of blood flow from the SMA to the proper hepatic artery.ResultsIn three of four patients, technical successes were achieved with sufficient margin from the originmore » of gastroduodenal artery. In one patient, the margin was less than 5 mm, although surgery was successfully performed without any problem. Eventually, all patients underwent the DP-CAR without arterial reconstruction or liver ischemia.ConclusionsAVP application is feasible and safe as an embolic procedure for preoperative CHA embolization of DP-CAR.« less

  9. Air motion determination by tracking humidity patterns in isentropic layers

    NASA Technical Reports Server (NTRS)

    Mancuso, R. L.; Hall, D. J.

    1975-01-01

    Determining air motions by tracking humidity patterns in isentropic layers was investigated. Upper-air rawinsonde data from the NSSL network and from the AVE-II pilot experiment were used to simulate temperature and humidity profile data that will eventually be available from geosynchronous satellites. Polynomial surfaces that move with time were fitted to the mixing-ratio values of the different isentropic layers. The velocity components of the polynomial surfaces are part of the coefficients that are determined in order to give an optimum fitting of the data. In the mid-troposphere, the derived humidity motions were in good agreement with the winds measured by rawinsondes so long as there were few or no clouds and the lapse rate was relatively stable. In the lower troposphere, the humidity motions were unreliable primarily because of nonadiabatic processes and unstable lapse rates. In the upper troposphere, the humidity amounts were too low to be measured with sufficient accuracy to give reliable results. However, it appears that humidity motions could be used to provide mid-tropospheric wind data over large regions of the globe.

  10. Development Status of Adjustable X-Ray Optics with 0.5 Arcsecond Resolution

    NASA Technical Reports Server (NTRS)

    Reid, P. B.; ODell, Stephen; Elsner, Ron; Ramsey, Brian; Gubarev, Misha; Aldcroft, T.; Allured, R.; Cotroneo, V.; Johnson-Wilke, R. L.; McMuldroch, S.; hide

    2014-01-01

    We report on the continuing development of adjustable, grazing incidence X-ray optics for 0.5 arcsec telescopes. Adjustable X-ray optics offer the potential for achieving sub-arcsecond imaging resolution while sufficiently thin and light-weight to constitute a mirror assembly with several square meters collecting area. The adjustable mirror concept employs a continuous thin film of piezoelectric material deposited on the back of the paraboloid and hyperboloid mirror segments. Individually addressable electrodes on the piezoelectric layer allow the introduction of deformations in localized "cells" which are used to correct mirror figure errors resulting from fabrication, mounting and aligning the thin mirrors, residual gravity release and temperature changes. We describe recent results of this development. These include improving cell yield to approx. 100 per cent, measurements of hysteresis and stability, comparisons of modeled and measured behavior, simulations of mirror performance, and the development and testing of conical Wolter- I mirror segments. We also present our plans going forward toward the eventual goal of achieving TRL 6 prior to the 2020 Decadal Review.

  11. Neutron stars and millisecond pulsars from accretion-induced collapse in globular clusters

    NASA Technical Reports Server (NTRS)

    Bailyn, Charles D.; Grindlay, Jonathan E.

    1990-01-01

    This paper examines the limits on the number of millisecond pulsars which could be formed in globular clusters by the generally accepted scenario (in which a neutron star is created by the supernova of an initially massive star and subsequently captures a companion to form a low-mass X-ray binary which eventually becomes a millisecond pulsar). It is found that, while the number of observed low-mass X-ray binaries can be adequately explained in this way, the reasonable assumption that the pulsar luminosity function in clusters extends below the current observational limits down to the luminosity of the faintest millisecond pulsars in the field suggests a cluster population of millisecond pulsars which is substantially larger than the standard model can produce. Alleviating this problem by postulating much shorter lifetimes for the X-ray binaries requires massive star populations sufficiently large that the mass loss resulting from their evolution would be likely to unbind the cluster. It is argued that neutron star formation in globular clusters by accretion-induced collapse of white dwarfs may resolve the discrepancy in birthrates.

  12. Design and testing of artifact-suppressed adaptive histogram equalization: a contrast-enhancement technique for display of digital chest radiographs.

    PubMed

    Rehm, K; Seeley, G W; Dallas, W J; Ovitt, T W; Seeger, J F

    1990-01-01

    One of the goals of our research in the field of digital radiography has been to develop contrast-enhancement algorithms for eventual use in the display of chest images on video devices with the aim of preserving the diagnostic information presently available with film, some of which would normally be lost because of the smaller dynamic range of video monitors. The ASAHE algorithm discussed in this article has been tested by investigating observer performance in a difficult detection task involving phantoms and simulated lung nodules, using film as the output medium. The results of the experiment showed that the algorithm is successful in providing contrast-enhanced, natural-looking chest images while maintaining diagnostic information. The algorithm did not effect an increase in nodule detectability, but this was not unexpected because film is a medium capable of displaying a wide range of gray levels. It is sufficient at this stage to show that there is no degradation in observer performance. Future tests will evaluate the performance of the ASAHE algorithm in preparing chest images for video display.

  13. Bifurcation and stability of single and multiple vortex rings in three-dimensional Bose-Einstein condensates

    DOE PAGES

    Bisset, R. N.; Wang, Wenlong; Ticknor, C.; ...

    2015-10-01

    Here, we investigate how single- and multi-vortex-ring states can emerge from a planar dark soliton in three-dimensional (3D) Bose-Einstein condensates (confined in isotropic or anisotropic traps) through bifurcations. We characterize such bifurcations quantitatively using a Galerkin-type approach and find good qualitative and quantitative agreement with our Bogoliubov–de Gennes (BdG) analysis. We also systematically characterize the BdG spectrum of the dark solitons, using perturbation theory, and obtain a quantitative match with our 3D BdG numerical calculations. We then turn our attention to the emergence of single- and multi-vortex-ring states. We systematically capture these as stationary states of the system and quantifymore » their BdG spectra numerically. We found that although the vortex ring may be unstable when bifurcating, its instabilities weaken and may even eventually disappear for sufficiently large chemical potentials and suitable trap settings. For instance, we demonstrate the stability of the vortex ring for an isotropic trap in the large-chemical-potential regime.« less

  14. Constructing Inexpensive, Flexible, and Versatile Microdialysis Probes in an Undergraduate Microdialysis Research Lab

    PubMed Central

    Steffes, Sally; Sandstrom, Michael

    2008-01-01

    Several challenges await new assistant professors setting up a neuroscience lab, and obtaining sufficient research help is typically a top priority. A secondary, but no less daunting, challenge is juggling accuracy and reliability with costs and limited start-up funds. These concerns are particularly crucial for those engaging technically sophisticated measurements, such as microdialysis. We have developed straightforward procedures that our undergraduate students have utilized to successfully construct high-quality, low-cost microdialysis probes. Students mastering the various steps involved have also gained valuable insight into their use, troubleshooting, and the implications of data obtained from these constructed probes. These procedures are explained here to foster increased use in neuroscience labs that involve undergraduates, along with pointers about teaching the technique to newcomers. Students who master the techniques can pass them on to new students easily. These procedures train students in the overall research technique of microdialysis more thoroughly than when manufactured probes are used, they save money, and will eventually save the principal investigator time when students develop independence with troubleshooting and repairs. PMID:23493044

  15. X-ray irradiation activates K+ channels via H2O2 signaling.

    PubMed

    Gibhardt, Christine S; Roth, Bastian; Schroeder, Indra; Fuck, Sebastian; Becker, Patrick; Jakob, Burkhard; Fournier, Claudia; Moroni, Anna; Thiel, Gerhard

    2015-09-09

    Ionizing radiation is a universal tool in tumor therapy but may also cause secondary cancers or cell invasiveness. These negative side effects could be causally related to the human-intermediate-conductance Ca2+-activated-K+-channel (hIK), which is activated by X-ray irradiation and affects cell proliferation and migration. To analyze the signaling cascade downstream of ionizing radiation we use genetically encoded reporters for H2O2 (HyPer) and for the dominant redox-buffer glutathione (Grx1-roGFP2) to monitor with high spatial and temporal resolution, radiation-triggered excursions of H2O2 in A549 and HEK293 cells. The data show that challenging cells with ≥1 Gy X-rays or with UV-A laser micro-irradiation causes a rapid rise of H2O2 in the nucleus and in the cytosol. This rise, which is determined by the rate of H2O2 production and glutathione-buffering, is sufficient for triggering a signaling cascade that involves an elevation of cytosolic Ca2+ and eventually an activation of hIK channels.

  16. X-ray irradiation activates K+ channels via H2O2 signaling

    PubMed Central

    Gibhardt, Christine S.; Roth, Bastian; Schroeder, Indra; Fuck, Sebastian; Becker, Patrick; Jakob, Burkhard; Fournier, Claudia; Moroni, Anna; Thiel, Gerhard

    2015-01-01

    Ionizing radiation is a universal tool in tumor therapy but may also cause secondary cancers or cell invasiveness. These negative side effects could be causally related to the human-intermediate-conductance Ca2+-activated-K+-channel (hIK), which is activated by X-ray irradiation and affects cell proliferation and migration. To analyze the signaling cascade downstream of ionizing radiation we use genetically encoded reporters for H2O2 (HyPer) and for the dominant redox-buffer glutathione (Grx1-roGFP2) to monitor with high spatial and temporal resolution, radiation-triggered excursions of H2O2 in A549 and HEK293 cells. The data show that challenging cells with ≥1 Gy X-rays or with UV-A laser micro-irradiation causes a rapid rise of H2O2 in the nucleus and in the cytosol. This rise, which is determined by the rate of H2O2 production and glutathione-buffering, is sufficient for triggering a signaling cascade that involves an elevation of cytosolic Ca2+ and eventually an activation of hIK channels. PMID:26350345

  17. Three Modes of Hydrogeophysical Investigation: Puzzles, Mysteries, and Conundrums

    NASA Astrophysics Data System (ADS)

    Ferre, P. A.

    2011-12-01

    In an article in the New Yorker in 2007, Malcolm Gladwell discussed the distinction that national security expert Gregory Treverton has made between puzzles and mysteries. Specifically, puzzles are problems that we understand and that will eventually be solved when we amass enough information. (Think crossword puzzles.) Mysteries are problems for which we have the necessary information, but it is often overwhelmed by irrelevant or misleading input. To solve a mystery, we require improved analysis. (Think find-a-word.) Gladwell goes on to explain that, in the national security realm, the Cold War was a puzzle while the current national security condition is a mystery. I will discuss the past, current, and future trajectories of hydrogeophysics in terms of puzzles and mysteries. I will also add a third class of problem: conundrums - those for which we lack sufficient information about their structure to know how to solve them. A conundrum is a mystery with an unexpected twist. I hope to make the case that the future growth of hydrogeophysics lies in our ability to address this more challenging and more interesting class of problem.

  18. Materials and Manufacturing Technologies Available for Production of a Pediatric Bioabsorbable Stent

    PubMed Central

    Alexy, Ryan D.; Levi, Daniel S.

    2013-01-01

    Transcatheter treatment of children with congenital heart disease such as coarctation of the aorta and pulmonary artery stenosis currently involves the use of metal stents. While these provide good short term results, there are long term complications with their use. Children outgrow metal stents, obligating them to future transcatheter dilations and eventual surgical removal. A bioabsorbable stent, or a stent that goes away with time, would solve this problem. Bioabsorbable stents are being developed for use in coronary arteries, however these are too small for use in pediatric congenital heart disease. A bioabsorbable stent for use in pediatric congenital heart disease needs to be low profile, expandable to a diameter 8 mm, provide sufficient radial strength, and absorb quickly enough to allow vessel growth. Development of absorbable coronary stents has led to a great understanding of the available production techniques and materials such as bioabsorbable polymers and biocorrodable metals. Children with congenital heart disease will hopefully soon benefit from the current generation of bioabsorbable and biocorrodable materials and devices. PMID:24089660

  19. The evolutionary origin of the need to sleep: an inevitable consequence of synaptic neurotransmission?

    PubMed

    Cantor, Robert S

    2015-01-01

    It is proposed that the evolutionary origin of the need to sleep is the removal of neurotransmitters (NTs) that escape reuptake and accumulate in brain interstitial fluid (ISF). Recent work suggests that the activity of ionotropic postsynaptic receptors, rapidly initiated by binding of NTs to extracellular sites, is modulated over longer times by adsorption of these NTs to the lipid bilayers in which the receptors are embedded. This bilayer-mediated mechanism is far less molecularly specific than binding, so bilayer adsorption of NTs that have diffused into synapses for other receptors would modulate their activity as well. Although NTs are recycled by membrane protein reuptake, the process is less than 100% efficient; a fraction escapes the region in which these specific reuptake proteins are localized and eventually diffuses throughout the ISF. It is estimated that even if only 0.1% of NTs escape reuptake, they would accumulate and adsorb to bilayers in synapses of other receptors sufficiently to affect receptor activity, the harmful consequences of which are avoided by sleep: a period of efficient convective clearance of solutes together with greatly reduced synaptic activity.

  20. Concurrent generation of functional smooth muscle and endothelial cells via a vascular progenitor.

    PubMed

    Marchand, Melanie; Anderson, Erica K; Phadnis, Smruti M; Longaker, Michael T; Cooke, John P; Chen, Bertha; Reijo Pera, Renee A

    2014-01-01

    Smooth muscle cells (SMCs) and endothelial cells (ECs) are typically derived separately, with low efficiencies, from human pluripotent stem cells (hPSCs). The concurrent generation of these cell types might lead to potential applications in regenerative medicine to model, elucidate, and eventually treat vascular diseases. Here we report a robust two-step protocol that can be used to simultaneously generate large numbers of functional SMCs and ECs from a common proliferative vascular progenitor population via a two-dimensional culture system. We show here that coculturing hPSCs with OP9 cells in media supplemented with vascular endothelial growth factor, basic fibroblast growth factor, and bone morphogenetic protein 4 yields a higher percentage of CD31(+)CD34(+) cells on day 8 of differentiation. Upon exposure to endothelial differentiation media and SM differentiation media, these vascular progenitors were able to differentiate and mature into functional endothelial cells and smooth muscle cells, respectively. Furthermore, we were able to expand the intermediate population more than a billion fold to generate sufficient numbers of ECs and SMCs in parallel for potential therapeutic transplantations.

  1. A formally verified algorithm for interactive consistency under a hybrid fault model

    NASA Technical Reports Server (NTRS)

    Lincoln, Patrick; Rushby, John

    1993-01-01

    Consistent distribution of single-source data to replicated computing channels is a fundamental problem in fault-tolerant system design. The 'Oral Messages' (OM) algorithm solves this problem of Interactive Consistency (Byzantine Agreement) assuming that all faults are worst-cass. Thambidurai and Park introduced a 'hybrid' fault model that distinguished three fault modes: asymmetric (Byzantine), symmetric, and benign; they also exhibited, along with an informal 'proof of correctness', a modified version of OM. Unfortunately, their algorithm is flawed. The discipline of mechanically checked formal verification eventually enabled us to develop a correct algorithm for Interactive Consistency under the hybrid fault model. This algorithm withstands $a$ asymmetric, $s$ symmetric, and $b$ benign faults simultaneously, using $m+1$ rounds, provided $n is greater than 2a + 2s + b + m$, and $m\\geg a$. We present this algorithm, discuss its subtle points, and describe its formal specification and verification in PVS. We argue that formal verification systems such as PVS are now sufficiently effective that their application to fault-tolerance algorithms should be considered routine.

  2. Specific Adaptation of Gas Atomization Processing for Al-Based Alloy Powder for Additive Manufacturing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, Iver; Siemon, John

    The initial three atomization attempts resulted in “freeze-outs” within the pour tubes in the pilot-scale system and yielded no powder. Re-evaluation of the alloy liquidus temperatures and melting characteristics, in collaboration with Alcoa, showed further superheat to be necessary to allow the liquid metal to flow through the pour tube to the atomization nozzle. A subsequent smaller run on the experimental atomization system verified these parameters and was successful, as were all successive runs on the larger pilot scale system. One alloy composition froze-out part way through the atomization on both pilot scale runs. SEM images showed needle formation andmore » phase segregations within the microstructure. Analysis of the pour tube freeze-out microstructures showed that large needles formed within the pour tube during the atomization experiment, which eventually blocked the melt stream. Alcoa verified the needle formation in this alloy using theoretical modeling of phase solidification. Sufficient powder of this composition was still generated to allow powder characterization and additive manufacturing trials at Alcoa.« less

  3. Early benefits of mitigation in risk of regional climate extremes

    NASA Astrophysics Data System (ADS)

    Ciavarella, Andrew; Stott, Peter; Lowe, Jason

    2017-04-01

    Large differences in climate outcomes are projected by the end of this century depending on whether greenhouse gas emissions continue to increase or are reduced sufficiently to limit total warming to below 2 °C (ref. ). However, it is generally thought that benefits of mitigation are hidden by internal climate variability until later in the century. Here we show that if the likelihood of extremely hot seasons is considered, the benefits of mitigation emerge more quickly than previously thought. It takes less than 20 years of emissions reductions in many regions for the likelihood of extreme seasonal warmth to reduce by more than half following initiation of mitigation. Additionally we show that the latest possible date at which the probability of extreme seasonal temperatures will be halved through emissions reductions consistent with the 2 °C target is in the 2040s. Exposure to climate risk is therefore reduced markedly and rapidly with substantial reductions of greenhouse gas emissions, demonstrating that the early mitigation needed to limit eventual warming below potentially dangerous levels benefits societies in the nearer term not just in the longer-term future.

  4. Simulation of multi-pulse coaxial helicity injection in the Sustained Spheromak Physics Experiment

    NASA Astrophysics Data System (ADS)

    O'Bryan, J. B.; Romero-Talamás, C. A.; Woodruff, S.

    2018-03-01

    Nonlinear, numerical computation with the NIMROD code is used to explore magnetic self-organization during multi-pulse coaxial helicity injection in the Sustained Spheromak Physics eXperiment. We describe multiple distinct phases of spheromak evolution, starting from vacuum magnetic fields and the formation of the initial magnetic flux bubble through multiple refluxing pulses and the eventual onset of the column mode instability. Experimental and computational magnetic diagnostics agree on the onset of the column mode instability, which first occurs during the second refluxing pulse of the simulated discharge. Our computations also reproduce the injector voltage traces, despite only specifying the injector current and not explicitly modeling the external capacitor bank circuit. The computations demonstrate that global magnetic evolution is fairly robust to different transport models and, therefore, that a single fluid-temperature model is sufficient for a broader, qualitative assessment of spheromak performance. Although discharges with similar traces of normalized injector current produce similar global spheromak evolution, details of the current distribution during the column mode instability impact the relative degree of poloidal flux amplification and magnetic helicity content.

  5. KSC-2009-1671

    NASA Image and Video Library

    2009-02-17

    CAPE CANAVERAL, Fla. – The Ares I-X fifth segment simulator aft section is lowered onto a stand in the Vehicle Assembly Building's extended duration orbiter lab, or EDO, at NASA's Kennedy Space Center in Florida. Ares I-X is the test vehicle for the Ares I, which is part of the Constellation Program to return men to the moon and beyond. Ares I is the essential core of a safe, reliable, cost-effective space transportation system that eventually will carry crewed missions back to the moon, on to Mars and out into the solar system. Ares I-X is targeted for launch in July 2009. Photo credit: NASA/Troy Cryder

  6. Anaplastic Large Cell Lymphoma Associated With Breast Implants

    PubMed Central

    Ravi-Kumar, Shalini; Sanaei, Omid; Vasef, Mohammad; Rabinowitz, Ian; Fekrazad, Mohammad Houman

    2012-01-01

    A forty two years old woman with a history of bilateral breast augmentation for cosmetic reasons was presented for poor healing of the surgical site. Tissue and periprosthetic fluid were removed from the wound site revealing an atypical lymphoid infiltrate. Subsequently the patient developed axillary lymph adenopathy. Excisional biopsy was performed. Flow cytometry was non-diagnostic. She continued to heal poorly and eventually had removal of implant during a simple mastectomy. A nodular area in the breast specimen showed ALK negative anaplastic large cell lymphoma (ALCL). The patient was treated in the private section, with only a pathology consultation being done at our institution (Figures 1-3). PMID:25734041

  7. Advanced Welding Torch

    NASA Technical Reports Server (NTRS)

    1996-01-01

    In order to more easily join the huge sections of the Space Shuttle external tank, Marshall Space Flight Center initiated development of the existing concept of Variable Polarity Plasma Arc (VPPA) welding. VPPA welding employs a variable current waveform that allows the system to operate for preset time increments in either of two polarity modes for effective joining of light alloys. Marshall awarded the torch contract to B & B Precision Machine, which produced a torch for the Shuttle, then automated the system, and eventually delivered a small torch used by companies such as Whirlpool for sheet metal welding of appliance parts and other applications. The dependability of the torch offers cost and time advantages.

  8. Positron studies in catalysis research

    NASA Astrophysics Data System (ADS)

    During the past eight months, the authors have made progress in several areas relevant to the eventual use of positron techniques in catalysis research. They have come closer to the completion of their positron microscope, and at the same time have performed several studies in their non-microscopic positron spectrometer which should ultimately be applicable to catalysis. The current status of the efforts in each of these areas is summarized in the following sections: Construction of the positron microscope (optical element construction, data collection software, and electronic sub-assemblies); Doppler broadening spectroscopy of metal silicide; Positron lifetime spectroscopy of glassy polymers; and Positron lifetime measurements of pore-sizes in zeolites.

  9. Corrosion on prehistoric Cu-Sn-alloys: the influence of artificial environment and storage

    NASA Astrophysics Data System (ADS)

    Mödlinger, Marianne; Piccardo, Paolo

    2013-12-01

    The paper contributes to the identification of different corrosion products detected on the cross-section specimens sampled from Bronze Age swords and one helmet found between 60-160 years ago. The objects are kept in 1889 built oak showcases at the Natural History Museum Vienna, having suffered unknown restoration treatments. The identified corrosion products not only affect further eventual treatment in conservation science of copper base objects but also contribute to identify the often unknown find context, which is meant to facilitate archaeological interpretation of the Bronze Age weapons. The analyses of the samples were carried out using SEM-EDXS-EBSD and optical microscopy.

  10. Evaluation of tantalum 316 stainless steel transition joints

    NASA Technical Reports Server (NTRS)

    Stoner, D. R.

    1972-01-01

    Tubular transition joints providing a metallurgically bonded connection between tantalum and 316 stainless steel pipe sections were comparatively evaluated for durability under thermal cycling conditions approximating the operation of a SNAP-8 mercury boiler. Both coextruded and vacuum brazed transition joints of 50mm (2 inch) diameter were tested by thermal cycling 100 times between 730 C and 120 C(1350 F and 250 F) in a high vacuum environment. The twelve evaluated transition joints survived the full test sequence without developing leaks, although liquid penetrant bond line indications eventually developed in all specimens. The brazed transition joints exhibited the best dimensional stability and bond line durability.

  11. STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT

    PubMed Central

    Brown, Wade H.; Pearce, Louise

    1923-01-01

    A malignant tumor which developed at the site of a primary syphilitic lesion in the scrotum of a rabbit, about 4 years after inoculation, and eventually led to the death of the animal, has formed the basis for an extensive series of investigations beginning with the study of the spontaneous tumor. The present report contains the clinical history of the animal from the time of inoculation to its death and the results of pathological examinations. The most important events recorded may be summarized as follows: 1. A mild but persistent syphilitic infection with an occasional relapse and the eventual development of chronic inflammatory lesions in the skin associated with atypical epithelial proliferations. 2. The occurrence, at about the same time, of extensive degenerative changes in the dermis accompanied by an atypical growth of hair follicles, with the production of diffuse and nodular areas of thickening and induration (scleroderma). 3. The development of a growth in the skin of the left scrotum which recurred after removal and spread diffusely over adjacent parts of the skin, and metastasized to the regional lymph nodes and to internal organs. 4. The transplantation of the growth to other rabbits by intratesticular inoculation and the successful propagation of the growth over a period of nearly 2 years (twenty generations). 5. The development of a cachexia and of pressure phenomena from metastases involving the cervical and lumbar regions of the spinal column which eventually led to the death of the animal. 6. The discovery, post mortem, of an extensive leucoplakia of the tongue and buccal mucosa, chronic inflammatory lesions in the esophagus with atypical epithelial proliferation, and a nodular growth in the left testicle differing in character from that in the scrotum. 7. The presence of extensive degenerative changes in the vascular system, degeneration of the parenchymatous organs, atrophy of the thymus and lymphoid system, with chronic lymphadenitis, atrophy, degeneration, and necrosis of the suprarenals, and atrophy and hyperplasia of the thyroid with chronic thyroiditis. The conclusion was reached that the growth in the scrotum represented a neoplasm of epithelial origin which was composed of cells allied to those found in the bulb and root sheath of the hair. No explanation was offered for the origin or unusual malignancy displayed by the tumor pending the introduction of experimental data. It was stated, however, that the evidence presented was sufficient to warrant the assumption that the factor of foremost importance in the development of the tumor was constitutional rather than local. PMID:19868747

  12. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the lumber derived therefrom are not “agricultural or horticultural commodities.” Christmas trees, whether wild or..., and harvesting of such trees or timber products is not sufficient to bring an employee within section...

  13. 29 CFR 780.115 - Forest products.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Agricultural Or Horticultural Commodities § 780.115 Forest products. Trees grown in forests and the lumber derived therefrom are not “agricultural or horticultural commodities.” Christmas trees, whether wild or..., and harvesting of such trees or timber products is not sufficient to bring an employee within section...

  14. 25 CFR 900.45 - What specific minimum requirements shall an Indian tribe or tribal organization's financial...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... (b) Accounting records. The financial management system shall maintain records sufficiently detailed... Principles for Educational Institutions.” (f) Source documentation. The financial management system shall... or tribal organization's financial management system contain to meet these standards? 900.45 Section...

  15. 12 CFR 615.5060 - Special collateral requirement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 615.5060 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL... requirement. (a) An attorney lien certification need not be obtained at the time a note is accepted as... association procedures provide sufficient safeguards to ensure that a real estate mortgage loan, within the...

  16. 13 CFR 120.410 - Requirements for all participating Lenders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Requirements for all participating Lenders. 120.410 Section 120.410 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS... small business loans including, but not limited to: (1) Holding sufficient permanent capital to support...

  17. 21 CFR 876.5020 - External penile rigidity devices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false External penile rigidity devices. 876.5020 Section 876.5020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... maintain sufficient penile rigidity for sexual intercourse. External penile rigidity devices include vacuum...

  18. 21 CFR 876.5020 - External penile rigidity devices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false External penile rigidity devices. 876.5020 Section 876.5020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... maintain sufficient penile rigidity for sexual intercourse. External penile rigidity devices include vacuum...

  19. 21 CFR 876.5020 - External penile rigidity devices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false External penile rigidity devices. 876.5020 Section 876.5020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... maintain sufficient penile rigidity for sexual intercourse. External penile rigidity devices include vacuum...

  20. 21 CFR 876.5020 - External penile rigidity devices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false External penile rigidity devices. 876.5020 Section 876.5020 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... maintain sufficient penile rigidity for sexual intercourse. External penile rigidity devices include vacuum...

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