Entanglement-Based dc Magnetometry with Separated Ions*

NASA Astrophysics Data System (ADS)

Ruster, T.; Kaufmann, H.; Luda, M. A.; Kaushal, V.; Schmiegelow, C. T.; Schmidt-Kaler, F.; Poschinger, U. G.

2017-07-01

We demonstrate sensing of inhomogeneous dc magnetic fields by employing entangled trapped ions, which are shuttled in a segmented Paul trap. As sensor states, we use Bell states of the type |↑↓ ⟩ +ei φ|↓↑ ⟩ encoded in two 40Ca+ ions stored at different locations. The linear Zeeman effect leads to the accumulation of a relative phase φ , which serves for measuring the magnetic-field difference between the constituent locations. Common-mode magnetic-field fluctuations are rejected by the entangled sensor state, which gives rise to excellent sensitivity without employing dynamical decoupling and therefore enables accurate dc sensing. Consecutive measurements on sensor states encoded in the S1 /2 ground state and in the D5 /2 metastable state are used to separate an ac Zeeman shift from the linear dc Zeeman effect. We measure magnetic-field differences over distances of up to 6.2 mm, with accuracies down to 300 fT and sensitivities down to 12 pT /√{Hz }. Our sensing scheme features spatial resolutions in the 20-nm range. For optimizing the information gain while maintaining a high dynamic range, we implement an algorithm for Bayesian frequency estimation.

KSC-08pd1192

NASA Image and Video Library

2008-05-07

CAPE CANAVERAL, Fla. -- Vibration and laser testing is being conducted on Ares I-X segments at NASA's Kennedy Space Center. Team members ( from left), Jim Gaspar, with NASA's Langley Research Center, Paul Bartollota, with NASA's Glenn Research Center, Ralph Buehrle, with Langley, and Ryan Tuttle, with Aerospace Corporation, evaluate test data. Photo credit: NASA/Dimitri Gerondidakis

Workforce Planning in the Intelligence Community: A Retrospective

DTIC Science & Technology

2013-01-01

segments of this work. We also wish to thank Dwayne M. Butler and Nelson Lim from RAND and Robert B. Murrett of the Syracuse University Department of Public...Taylor, Richard Eisenman, William Fedorochko, Clifford M. Graf II, Mark Hoyer, Paul Bracken, Norman T. O’Meara, Jerry M. Sollinger, Judith Larson

Off-resonance energy absorption in a linear Paul trap due to mass selective resonant quenching

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sivarajah, I.; Goodman, D. S.; Wells, J. E.

Linear Paul traps (LPT) are used in many experimental studies such as mass spectrometry, atom-ion collisions, and ion-molecule reactions. Mass selective resonant quenching (MSRQ) is implemented in LPT either to identify a charged particle's mass or to remove unwanted ions from a controlled experimental environment. In the latter case, MSRQ can introduce undesired heating to co-trapped ions of different mass, whose secular motion is off resonance with the quenching ac field, which we call off-resonance energy absorption (OREA). We present simulations and experimental evidence that show that the OREA increases exponentially with the number of ions loaded into the trapmore » and with the amplitude of the off-resonance external ac field.« less

Re-entry vehicle shape for enhanced performance

NASA Technical Reports Server (NTRS)

Brown, James L. (Inventor); Garcia, Joseph A. (Inventor); Prabhu, Dinesh K. (Inventor)

2008-01-01

A convex shell structure for enhanced aerodynamic performance and/or reduced heat transfer requirements for a space vehicle that re-enters an atmosphere. The structure has a fore-body, an aft-body, a longitudinal axis and a transverse cross sectional shape, projected on a plane containing the longitudinal axis, that includes: first and second linear segments, smoothly joined at a first end of each the first and second linear segments to an end of a third linear segment by respective first and second curvilinear segments; and a fourth linear segment, joined to a second end of each of the first and second segments by curvilinear segments, including first and second ellipses having unequal ellipse parameters. The cross sectional shape is non-symmetric about the longitudinal axis. The fourth linear segment can be replaced by a sum of one or more polynomials, trigonometric functions or other functions satisfying certain constraints.

SELECTED PAPERS FROM PROFESSIONAL PROGRAM SEGMENTS OF UNITED CEREBRAL PALSY'S ANNUAL CONFERENCE (15TH, LOS ANGELES, CALIFORNIA, MARCH 11-13, 1965).

ERIC Educational Resources Information Center

United Cerebral Palsy Association, New York, NY.

THIS PUBLICATION PRESENTS SELECTED PAPERS FROM THE UNITED CEREBRAL PALSY ASSOCIATION'S 15TH ANNUAL CONFERENCE, MARCH 13, 1965. PAPERS ARE--(1) "S IS TO TURN" BY PAUL V. CARLSON, (2) "CERTAIN ASPECTS OF THE FUNCTIONAL STATUS OF THE FETUS IN UTERO" BY FORREST H. ADAMS, (3) "ENCEPHALITIS--COMMON CAUSES AND AFTER EFFECTS"…

Aharonov-Bohm effect in the tunnelling of a quantum rotor in a linear Paul trap.

PubMed

Noguchi, Atsushi; Shikano, Yutaka; Toyoda, Kenji; Urabe, Shinji

2014-05-13

Quantum tunnelling is a common fundamental quantum mechanical phenomenon that originates from the wave-like characteristics of quantum particles. Although the quantum tunnelling effect was first observed 85 years ago, some questions regarding the dynamics of quantum tunnelling remain unresolved. Here we realize a quantum tunnelling system using two-dimensional ionic structures in a linear Paul trap. We demonstrate that the charged particles in this quantum tunnelling system are coupled to the vector potential of a magnetic field throughout the entire process, even during quantum tunnelling, as indicated by the manifestation of the Aharonov-Bohm effect in this system. The tunnelling rate of the structures periodically depends on the strength of the magnetic field, whose period is the same as the magnetic flux quantum φ0 through the rotor [(0.99 ± 0.07) × φ0].

Deceleration, precooling, and multi-pass stopping of highly charged ions in Be{sup +} Coulomb crystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmöger, L., E-mail: lisa.schmoeger@mpi-hd.mpg.de; Schwarz, M.; Versolato, O. O.

2015-10-15

Preparing highly charged ions (HCIs) in a cold and strongly localized state is of particular interest for frequency metrology and tests of possible spatial and temporal variations of the fine structure constant. Our versatile preparation technique is based on the generic modular combination of a pulsed ion source with a cryogenic linear Paul trap. Both instruments are connected by a compact beamline with deceleration and precooling properties. We present its design and commissioning experiments regarding these two functionalities. A pulsed buncher tube allows for the deceleration and longitudinal phase-space compression of the ion pulses. External injection of slow HCIs, specificallymore » Ar{sup 13+}, into the linear Paul trap and their subsequent retrapping in the absence of sympathetic cooling is demonstrated. The latter proved to be a necessary prerequisite for the multi-pass stopping of HCIs in continuously laser-cooled Be{sup +} Coulomb crystals.« less

New Steering Strategies for the USNO Master Clocks

DTIC Science & Technology

1999-12-01

1992. P. Koppang and R. Leland , “Linear quadratic stochastic control of atomic hydrogen masers,” IEEE Trans. Ultrason., Ferroelect., Freq. Contr...vol. 46, pp. 517-522, May 1999. P. Koppang and R. Leland , “Steering of frequency standards by the use of linear quadratic gaussian control theory...3lst Annual Precise Time and Time Interval (PTTI) Meeting NEWSTEERINGSTRATEGIESFOR THEUSNOMASTERCLOCKS Paul A. Koppang Datum, Inc. Beverly, MA

Particular Oceanic Core Complex evolution in an extremely low melt supply environment

NASA Astrophysics Data System (ADS)

Maia, M.; Vincent, C.; Briais, A.; Brunelli, D.; Ligi, M.; Adrião, Á.; Sichel, S. E.

2017-12-01

Saint Paul is a major transform system in the Equatorial Mid-Atlantic Ridge. It consists of four transform faults and three short intra-transform ridge segments. This study focuses on peridotitic and gabbroic ridges and unusual Oceanic Core Complex (OCC)-related tectonics found at the St. Paul southern intra-transform segment. These structures display the same characters as the OCCs worldwide (termination, rafted blocks, corrugations, breakaway); however unusual features suggest that they have evolved in a particular way with respect to other OCCs along the Mid-Atlantic Ridge. Small ridge segments display an asymmetrical accretion through successive nucleations of detachment faults over more than 10 m.y. marked by crustal mylonitisation (Adrião et al., this session). Structural mapping and gravity models covering about 100 km on each ridge flank confirm the existence of four consecutive detachments, the more recent being still active, and provide an interpretative model of their spatiotemporal evolution. The unusual aspect is that each detachment appears to have been split on the two sides of the ridge axis. As a consequence, the breakaways are located on the American plate, while the conjugate terminations are drafted away on the African plate. We suggest that this unusual feature results from the rupture of the detachment surfaces by relocation of the ridge axis through westward small ridge jumps. This mode of expansion is somehow intermediate between the "normal" OCCs spreading and the Smooth Seafloor-type model described off-axis along the Southwest Indian Ridge (Sauter et al., 2013). It partly compensates the long-term asymmetric expansion of this ridge segment and is likely related to the extremely low melt supply and thick lithosphere inferred from other studies. Adrião et al., 2017. Mechanical mixing and metamorphism of mafic and ultramafic lithologies .... This Session Sauter et al., 2013. Continuous exhumation of mantle-derived rocks… Nat Geo, 2013

Intrinsic anharmonic effects on the phonon frequencies and effective spin-spin interactions in a quantum simulator made from trapped ions in a linear Paul trap

NASA Astrophysics Data System (ADS)

McAneny, M.; Freericks, J. K.

2014-11-01

The Coulomb repulsion between ions in a linear Paul trap gives rise to anharmonic terms in the potential energy when expanded about the equilibrium positions. We examine the effect of these anharmonic terms on the accuracy of a quantum simulator made from trapped ions. To be concrete, we consider a linear chain of Yb171+ ions stabilized close to the zigzag transition. We find that for typical experimental temperatures, frequencies change by no more than a factor of 0.01 % due to the anharmonic couplings. Furthermore, shifts in the effective spin-spin interactions (driven by a spin-dependent optical dipole force) are also, in general, less than 0.01 % for detunings to the blue of the transverse center-of-mass frequency. However, detuning the spin interactions near other frequencies can lead to non-negligible anharmonic contributions to the effective spin-spin interactions. We also examine an odd behavior exhibited by the harmonic spin-spin interactions for a range of intermediate detunings, where nearest-neighbor spins with a larger spatial separation on the ion chain interact more strongly than nearest neighbors with a smaller spatial separation.

Climbing robot. [caterpillar design

NASA Technical Reports Server (NTRS)

Kerley, James J. (Inventor); May, Edward L. (Inventor); Ecklund, Wayne D. (Inventor)

1993-01-01

A mobile robot for traversing any surface consisting of a number of interconnected segments, each interconnected segment having an upper 'U' frame member, a lower 'U' frame member, a compliant joint between the upper 'U' frame member and the lower 'U' frame member, a number of linear actuators between the two frame members acting to provide relative displacement between the frame members, a foot attached to the lower 'U' frame member for adherence of the segment to the surface, an inter-segment attachment attached to the upper 'U' frame member for interconnecting the segments, a power source connected to the linear actuator, and a computer/controller for independently controlling each linear actuator in each interconnected segment such that the mobile robot moves in a caterpillar like fashion.

Predictors of Adolescent Breakfast Consumption: Longitudinal Findings from Project EAT

ERIC Educational Resources Information Center

Bruening, Meg; Larson, Nicole; Story, Mary; Neumark-Sztainer, Dianne; Hannan, Peter

2011-01-01

Objective: To identify predictors of breakfast consumption among adolescents. Methods: Five-year longitudinal study Project EAT (Eating Among Teens). Baseline surveys were completed in Minneapolis-St. Paul schools and by mail at follow-up by youth (n = 800) transitioning from middle to high school. Linear regression models examined associations…

Investigation on electromechanical properties of a muscle-like linear actuator fabricated by bi-film ionic polymer metal composites

NASA Astrophysics Data System (ADS)

Sun, Zhuangzhi; Zhao, Gang; Qiao, Dongpan; Song, Wenlong

2017-12-01

Artificial muscles have attracted great attention for their potentials in intelligent robots, biomimetic devices, and micro-electromechanical system. However, there are many performance bottlenecks restricting the development of artificial muscles in engineering applications, e.g., the little blocking force and short working life. Focused on the larger requirements of the output force and the lack characteristics of the linear motion, an innovative muscle-like linear actuator based on two segmented IPMC strips was developed to imitate linear motion of artificial muscles. The structures of the segmented IPMC strip of muscle-like linear actuator were developed and the established mathematical model was to determine the appropriate segmented proportion as 1:2:1. The muscle-like linear actuator with two segmented IPMC strips assemble by two supporting link blocks was manufactured for the study of electromechanical properties. Electromechanical properties of muscle-like linear actuator under the different technological factors were obtained to experiment, and the corresponding changing rules of muscle-like linear actuators were presented to research. Results showed that factors of redistributed resistance and surface strain on both end-sides were two main reasons affecting the emergence of different electromechanical properties of muscle-like linear actuators.

STS-113 Post Flight Presentation

NASA Astrophysics Data System (ADS)

2002-01-01

The STS-113 post-flight presentation begins with a view of Mission Specialists Michael E. Lopez-Alegria and John B. Herrington getting suited for the space mission. The STS-113 crew consists of: Commander James D. Wetherbee, Pilot Paul Lockhart, Mission Specialists Michael Lopez-Alegria and John Herrington. Cosmonauts Valery Korzun, and Sergei Treschev, and astronaut Peggy Whitson who are all members of the expedition five crew, and Commander Kenneth Bowersox, Flight Engineers Nikolai Budarin and Donald Pettit, members of Expedition Six. The main goal of this mission is to take Expedition Six up to the International Space Station and Return Expedition Five to the Earth. The second objective is to install the P(1) Truss segment. Three hours prior to launch, the crew of Expedition Six along with James Wetherbee, Paul Lockhart, Michael Lopez-Alegria and John Herrington are shown walking to an astrovan, which takes them to the launch pad. The actual liftoff is presented. Three Extravehicular Activities (EVA)'s are performed on this mission. Michael Lopez-Alegria and John Herrington are shown performing EVA 1 and EVA 2 which include making connections between the P1 and S(0) Truss segments, and installing fluid jumpers. A panoramic view of the ISS with the Earth in the background is shown. The grand ceremony of the crew exchange is presented. The astronauts performing everyday duties such as brushing teeth, washing hair, sleeping, and eating pistachio nuts are shown. The actual landing of the Space Shuttle is presented.

Segmented rail linear induction motor

DOEpatents

Cowan, Jr., Maynard; Marder, Barry M.

1996-01-01

A segmented rail linear induction motor has a segmented rail consisting of a plurality of nonferrous electrically conductive segments aligned along a guideway. The motor further includes a carriage including at least one pair of opposed coils fastened to the carriage for moving the carriage. A power source applies an electric current to the coils to induce currents in the conductive surfaces to repel the coils from adjacent edges of the conductive surfaces.

Wide Linear Corticotomy and Anterior Segmental Osteotomy Under Local Anesthesia Combined Corticision for Correcting Severe Anterior Protrusion With Insufficient Alveolar Housing.

PubMed

Noh, Min-Ki; Lee, Baek-Soo; Kim, Shin-Yeop; Jeon, Hyeran Helen; Kim, Seong-Hun; Nelson, Gerald

2017-11-01

This article presents an alternate surgical treatment method to correct a severe anterior protrusion in an adult patient with an extremely thin alveolus. To accomplish an effective and efficient anterior segmental retraction without periodontal complications, the authors performed, under local anesthesia, a wide linear corticotomy and corticision in the maxilla and an anterior segmental osteotomy in mandible. In the maxilla, a wide linear corticotomy was performed under local anesthesia. In the maxillary first premolar area, a wide section of cortical bone was removed. Retraction forces were applied buccolingually with the aid of temporary skeletal anchorage devices. Corticision was later performed to close residual extraction space. In the mandible, an anterior segmental osteotomy was performed and the first premolars were extracted under local anesthesia. In the maxilla, a wide linear corticotomy facilitated a bony block movement with temporary skeletal anchorage devices, without complications. The remaining extraction space after the bony block movement was closed effectively, accelerated by corticision. In the mandible, anterior segmental retraction was facilitated by an anterior segmental osteotomy performed under local anesthesia. Corticision was later employed to accelerate individual tooth movements. A wide linear corticotomy and an anterior segmental osteotomy combined with corticision can be an effective and efficient alternative to conventional orthodontic treatment in the bialveolar protrusion patient with an extremely thin alveolar housing.

Young children make their gestural communication systems more language-like: segmentation and linearization of semantic elements in motion events.

PubMed

Clay, Zanna; Pople, Sally; Hood, Bruce; Kita, Sotaro

2014-08-01

Research on Nicaraguan Sign Language, created by deaf children, has suggested that young children use gestures to segment the semantic elements of events and linearize them in ways similar to those used in signed and spoken languages. However, it is unclear whether this is due to children's learning processes or to a more general effect of iterative learning. We investigated whether typically developing children, without iterative learning, segment and linearize information. Gestures produced in the absence of speech to express a motion event were examined in 4-year-olds, 12-year-olds, and adults (all native English speakers). We compared the proportions of gestural expressions that segmented semantic elements into linear sequences and that encoded them simultaneously. Compared with adolescents and adults, children reshaped the holistic stimuli by segmenting and recombining their semantic features into linearized sequences. A control task on recognition memory ruled out the possibility that this was due to different event perception or memory. Young children spontaneously bring fundamental properties of language into their communication system. © The Author(s) 2014.

Using Commercial-Off-The-Shelf Speech Recognition Software for Conning U.S. Warships

DTIC Science & Technology

2003-06-01

Linear Regression , 2nd Edition, (John Wiley & Sons, St. Paul, Minnesota, 1985), pp. 267-269. 44 Current Projects About the Sigmoid Curve, Sigmoid Curve...Disabilities Conference, Conference Proceedings, [www.csun.edu/cod/conf/1998/proceedings/csun98_052.htm], as of June 2, 2003. 43 Weisberg, S., Applied

Proof Theory for Authorization Logic and Its Application to a Practical File System

DTIC Science & Technology

2009-12-01

Holland, 1969. [71] Jean-Yves Girard. Linear logic. Theoretical Computer Science, 50:1–102, 1987 . [72] Jean-Yves Girard, Paul Taylor, and Yves Lafont...2009. Online at http://ecommons.library.cornell.edu/handle/1813/13679. [133] S. Shepler, B. Callaghan, D. Robinson, R. Thurlow, C. Beame, M. Eisler , and

Segmented rail linear induction motor

DOEpatents

Cowan, M. Jr.; Marder, B.M.

1996-09-03

A segmented rail linear induction motor has a segmented rail consisting of a plurality of nonferrous electrically conductive segments aligned along a guideway. The motor further includes a carriage including at least one pair of opposed coils fastened to the carriage for moving the carriage. A power source applies an electric current to the coils to induce currents in the conductive surfaces to repel the coils from adjacent edges of the conductive surfaces. 6 figs.

[Superimposed lichen planus pigmentosus].

PubMed

Monteagudo, Benigno; Suarez-Amor, Óscar; Cabanillas, Miguel; de Las Heras, Cristina; Álvarez, Juan Carlos

2014-05-16

Lichen planus pigmentosus is an uncommon variant of lichen planus that is characterized by the insidious onset of dark brown macules in sun-exposed areas and flexural folds. Superimposed linear lichen planus is an exceedingly rare disorder, but it has been found in both lichen planopilaris and lichen planus types. A 39-year-old woman is presented showing a segmental and linear lichen planus associated with non-segmental lesions meeting all criteria for the diagnosis of superimposed linear planus pigmentosus. The segmental lesions were always more pronounced.

Video Image Tracking Engine

NASA Technical Reports Server (NTRS)

Howard, Richard T. (Inventor); Bryan, ThomasC. (Inventor); Book, Michael L. (Inventor)

2004-01-01

A method and system for processing an image including capturing an image and storing the image as image pixel data. Each image pixel datum is stored in a respective memory location having a corresponding address. Threshold pixel data is selected from the image pixel data and linear spot segments are identified from the threshold pixel data selected.. Ihe positions of only a first pixel and a last pixel for each linear segment are saved. Movement of one or more objects are tracked by comparing the positions of fust and last pixels of a linear segment present in the captured image with respective first and last pixel positions in subsequent captured images. Alternatively, additional data for each linear data segment is saved such as sum of pixels and the weighted sum of pixels i.e., each threshold pixel value is multiplied by that pixel's x-location).

Seafloor spreading on the Amsterdam-St. Paul hotspot plateau

NASA Astrophysics Data System (ADS)

Conder, James A.; Scheirer, Daniel S.; Forsyth, Donald W.

2000-04-01

The Amsterdam-St. Paul (ASP) platform on the intermediate rate Southeast Indian Ridge (SEIR) is the only oceanic hotspot plateau outside the Atlantic Ocean containing an active, mid-ocean ridge spreading axis. Because the ASP hotspot is small and remotely located, it has been relatively unstudied, and the ridge axis location in many places near the ASP plateau was previously unknown or ambiguous. We mapped the SEIR out to 1 Ma crust (Jaramillo anomaly) both on and near the ASP platform. We located the spreading center to within a few kilometers, based on side-scan sonar reflectivity. Recent off-platform magnetic anomalies and lineated abyssal hill topography are consistent with a simple spreading history. Off-platform full spreading rates increase from ˜63 km/Myr on segment H to the north of the platform to ˜65.5 km/Myr on segment K to the south. In contrast, inversions of seafloor magnetization based on uniform and variable thickness magnetic source layers reflect a complex on-platform tectonic history with ridge jumps, off-axis volcanism, and propagating rifts. On one section of the ASP plateau the spreading location has stabilized and is beginning to rift the plateau apart, generating symmetric magnetic anomalies and lineated topography for the last several hundred thousand years. The larger, more stable, spreading segments of the ASP platform are aligned with major volcanic edifices, suggesting that along-axis magma flow away from plume-fed centers is an important influence on spreading geometry. Many complex tectonic features observed on the ASP plateau, such as ridge jumps, en echelon, oblique spreading centers, and transforms oblique to the spreading direction, are comparable to features observed on Iceland. The similarities suggest that moderate crustal thickening at an intermediate rate spreading center may have similar effects to pronounced thickening at a slow rate spreading center.

Thermal-Interaction Matrix For Resistive Test Structure

NASA Technical Reports Server (NTRS)

Buehler, Martin G.; Dhiman, Jaipal K.; Zamani, Nasser

1990-01-01

Linear mathematical model predicts increase in temperature in each segment of 15-segment resistive structure used to test electromigration. Assumption of linearity based on fact: equations that govern flow of heat are linear and coefficients in equations (heat conductivities and capacities) depend only weakly on temperature and considered constant over limited range of temperature.

Metric Learning for Hyperspectral Image Segmentation

NASA Technical Reports Server (NTRS)

Bue, Brian D.; Thompson, David R.; Gilmore, Martha S.; Castano, Rebecca

2011-01-01

We present a metric learning approach to improve the performance of unsupervised hyperspectral image segmentation. Unsupervised spatial segmentation can assist both user visualization and automatic recognition of surface features. Analysts can use spatially-continuous segments to decrease noise levels and/or localize feature boundaries. However, existing segmentation methods use tasks-agnostic measures of similarity. Here we learn task-specific similarity measures from training data, improving segment fidelity to classes of interest. Multiclass Linear Discriminate Analysis produces a linear transform that optimally separates a labeled set of training classes. The defines a distance metric that generalized to a new scenes, enabling graph-based segmentation that emphasizes key spectral features. We describe tests based on data from the Compact Reconnaissance Imaging Spectrometer (CRISM) in which learned metrics improve segment homogeneity with respect to mineralogical classes.

Rotational dynamics of a diatomic molecular ion in a Paul trap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hashemloo, A.; Dion, C. M., E-mail: claude.dion@umu.se

We present models for a heteronuclear diatomic molecular ion in a linear Paul trap in a rigid-rotor approximation, one purely classical and the other where the center-of-mass motion is treated classically, while rotational motion is quantized. We study the rotational dynamics and their influence on the motion of the center-of-mass, in the presence of the coupling between the permanent dipole moment of the ion and the trapping electric field. We show that the presence of the permanent dipole moment affects the trajectory of the ion and that it departs from the Mathieu equation solution found for atomic ions. For themore » case of quantum rotations, we also evidence the effect of the above-mentioned coupling on the rotational states of the ion.« less

Robust Segmentation of Planar and Linear Features of Terrestrial Laser Scanner Point Clouds Acquired from Construction Sites.

PubMed

Maalek, Reza; Lichti, Derek D; Ruwanpura, Janaka Y

2018-03-08

Automated segmentation of planar and linear features of point clouds acquired from construction sites is essential for the automatic extraction of building construction elements such as columns, beams and slabs. However, many planar and linear segmentation methods use scene-dependent similarity thresholds that may not provide generalizable solutions for all environments. In addition, outliers exist in construction site point clouds due to data artefacts caused by moving objects, occlusions and dust. To address these concerns, a novel method for robust classification and segmentation of planar and linear features is proposed. First, coplanar and collinear points are classified through a robust principal components analysis procedure. The classified points are then grouped using a new robust clustering method, the robust complete linkage method. A robust method is also proposed to extract the points of flat-slab floors and/or ceilings independent of the aforementioned stages to improve computational efficiency. The applicability of the proposed method is evaluated in eight datasets acquired from a complex laboratory environment and two construction sites at the University of Calgary. The precision, recall, and accuracy of the segmentation at both construction sites were 96.8%, 97.7% and 95%, respectively. These results demonstrate the suitability of the proposed method for robust segmentation of planar and linear features of contaminated datasets, such as those collected from construction sites.

Robust Segmentation of Planar and Linear Features of Terrestrial Laser Scanner Point Clouds Acquired from Construction Sites

PubMed Central

Maalek, Reza; Lichti, Derek D; Ruwanpura, Janaka Y

2018-01-01

Automated segmentation of planar and linear features of point clouds acquired from construction sites is essential for the automatic extraction of building construction elements such as columns, beams and slabs. However, many planar and linear segmentation methods use scene-dependent similarity thresholds that may not provide generalizable solutions for all environments. In addition, outliers exist in construction site point clouds due to data artefacts caused by moving objects, occlusions and dust. To address these concerns, a novel method for robust classification and segmentation of planar and linear features is proposed. First, coplanar and collinear points are classified through a robust principal components analysis procedure. The classified points are then grouped using a new robust clustering method, the robust complete linkage method. A robust method is also proposed to extract the points of flat-slab floors and/or ceilings independent of the aforementioned stages to improve computational efficiency. The applicability of the proposed method is evaluated in eight datasets acquired from a complex laboratory environment and two construction sites at the University of Calgary. The precision, recall, and accuracy of the segmentation at both construction sites were 96.8%, 97.7% and 95%, respectively. These results demonstrate the suitability of the proposed method for robust segmentation of planar and linear features of contaminated datasets, such as those collected from construction sites. PMID:29518062

Formation and Elimination of Transform Faults on the Reykjanes Ridge

NASA Astrophysics Data System (ADS)

Martinez, Fernando; Hey, Richard

2017-04-01

The Reykjanes Ridge is a type-setting for examining processes that form and eliminate transform faults because it has undergone these events systematically within the Iceland gradient in hot-spot influence. A Paleogene change in plate motion led to the abrupt segmentation of the originally linear axis into a stair-step ridge-transform configuration. Its subsequent evolution diachronously and systematically eliminated the just-formed offsets re-establishing the original linear geometry of the ridge over the mantle, although now spreading obliquely. During segmented stages accreted crust was thinner and during unsegmented stages southward pointing V-shaped crustal ridges formed. Although mantle plume effects have been invoked to explain the changes in segmentation and crustal features, we propose that plate boundary processes can account for these changes [Martinez & Hey, EPSL, 2017]. Fragmentation of the axis was a mechanical effect of an abrupt change in plate opening direction, as observed in other areas, and did not require mantle plume temperature changes. Reassembly of the fragmented axis to its original linear configuration was controlled by a deep damp melting regime that persisted in a linear configuration following the abrupt change in opening direction. Whereas the shallow and stronger mantle of the dry melting regime broke up into a segmented plate boundary, the persistent deep linear damp melting regime guided reassembly of the ridge axis back to its original configuration by inducing asymmetric spreading of individual ridge segments. Effects of segmentation on mantle upwelling explain crustal thickness changes between segmented and unsegmented phases of spreading without mantle temperature changes. Buoyant upwelling instabilities propagate along the long linear deep melting regime driven by regional gradients in mantle properties away from Iceland. Once segmentation is eliminated, these propagating upwelling instabilities lead to crustal thickness variations forming the V-shaped ridges on the Reykjanes Ridge flanks, without requiring actual rapid radial mantle plume flow or temperature variations. Our study indicates that the Reykjanes Ridge can be used to study how plate boundary processes within a regional gradient in mantle properties lead to a range of effects on lithospheric segmentation, melt production and crustal accretion.

STS-113 crew during M-113 armored personnel carrier training

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- The STS-113 crew pause for a photo after test drives in the M-113 armored personnel carrier behind them. From left are Mission Specialist Michael Lopez-Alegria, Pilot Paul Lockhart, Commander James Wetherbee and Mission Specialist John Herrington. Driving the M-113 is part of emergency egress training at the pad, one of the Terminal Countdown Demonstration Test activities in preparation for launch. The TCDT also includes a simulated launch countdown. The primary payloads on mission STS-113 are the first port truss segment, P1, and the Crew and Equipment Translation Aid (CETA) Cart B. Once delivered, the P1 truss will remain stowed until flight 12A.1 in 2003 when it will be attached to the central truss segment, S0, on the Space Station. Also onboard Space Shuttle Endeavour will be the Expedition 6 crew who will replace Expedition 5, returning to Earth after 4 months.

STS-113 crew during M-113 armored personnel carrier training

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- STS-113 Pilot Paul Lockhart test drives an M-113 armored personnel carrier, part of emergency egress training during Terminal Countdown Demonstration Test activities. He is accompanied by several other crew members, seen at left, Mission Specialist Michael Lopez-Alegria and Commander James Wetherbee. The crew is preparing for the mission aboard Space Shuttle Endeavour, which is scheduled to launch Nov. 10. The TCDT includes a simulated launch countdown. The primary payloads on mission STS-113 are the first port truss segment, P1, and the Crew and Equipment Translation Aid (CETA) Cart B. Once delivered, the P1 truss will remain stowed until flight 12A.1 in 2003 when it will be attached to the central truss segment, S0, on the Space Station. Also onboard Space Shuttle Endeavour will be the Expedition 6 crew who will replace Expedition 5, returning to Earth after 4 months.

STS-113 crew during M-113 armored personnel carrier training

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- STS-113 Pilot Paul Lockhart stands inside an M-113 armored personnel carrier he is about to drive, part of emergency egress training during Terminal Countdown Demonstration Test activities. He and the rest of the crew are preparing for the mission aboard Space Shuttle Endeavour, which is scheduled to launch Nov. 10. The TCDT includes a simulated launch countdown. The primary payloads on mission STS-113 are the first port truss segment, P1, and the Crew and Equipment Translation Aid (CETA) Cart B. Once delivered, the P1 truss will remain stowed until flight 12A.1 in 2003 when it will be attached to the central truss segment, S0, on the Space Station. Also onboard Space Shuttle Endeavour will be the Expedition 6 crew who will replace Expedition 5, returning to Earth after 4 months.

KSC-02pd1554

NASA Image and Video Library

2002-10-16

KENNEDY SPACE CENTER, FLA. -- The STS-113 crew pause for a photo after test drives in the M-113 armored personnel carrier behind them. From left are Mission Specialist Michael Lopez-Alegria, Pilot Paul Lockhart, Commander James Wetherbee and Mission Specialist John Herrington. Driving the M-113 is part of emergency egress training at the pad, one of the Terminal Countdown Demonstration Test activities in preparation for launch. The TCDT also includes a simulated launch countdown. The primary payloads on mission STS-113 are the first port truss segment, P1, and the Crew and Equipment Translation Aid (CETA) Cart B. Once delivered, the P1 truss will remain stowed until flight 12A.1 in 2003 when it will be attached to the central truss segment, S0, on the Space Station. Also onboard Space Shuttle Endeavour will be the Expedition 6 crew who will replace Expedition 5, returning to Earth after 4 months.

Segmented amplifier configurations for laser amplifier

DOEpatents

Hagen, Wilhelm F.

1979-01-01

An amplifier system for high power lasers, the system comprising a compact array of segments which (1) preserves high, large signal gain with improved pumping efficiency and (2) allows the total amplifier length to be shortened by as much as one order of magnitude. The system uses a three dimensional array of segments, with the plane of each segment being oriented at substantially the amplifier medium Brewster angle relative to the incident laser beam and with one or more linear arrays of flashlamps positioned between adjacent rows of amplifier segments, with the plane of the linear array of flashlamps being substantially parallel to the beam propagation direction.

Correlated patterns in hydrothermal plume distribution and apparent magmatic budget along 2500 km of the Southeast Indian Ridge

USGS Publications Warehouse

Baker, Edward; Christophe Hémond,; Anne Briais,; Marcia Maia,; Scheirer, Daniel S.; Sharon L. Walker,; Tingting Wang,; Yongshun John Chen,

2014-01-01

Multiple geological processes affect the distribution of hydrothermal venting along a mid-ocean ridge. Deciphering the role of a specific process is often frustrated by simultaneous changes in other influences. Here we take advantage of the almost constant spreading rate (65–71 mm/yr) along 2500 km of the Southeast Indian Ridge (SEIR) between 77°E and 99°E to examine the spatial density of hydrothermal venting relative to regional and segment-scale changes in the apparent magmatic budget. We use 227 vertical profiles of light backscatter and (on 41 profiles) oxidation-reduction potential along 27 first and second-order ridge segments on and adjacent to the Amsterdam-St. Paul (ASP) Plateau to map ph, the fraction of casts detecting a plume. At the regional scale, venting on the five segments crossing the magma-thickened hot spot plateau is almost entirely suppressed (ph = 0.02). Conversely, the combined ph (0.34) from all other segments follows the global trend of ph versus spreading rate. Off the ASP Plateau, multisegment trends in ph track trends in the regional axial depth, high where regional depth increases and low where it decreases. At the individual segment scale, a robust correlation between ph and cross-axis inflation for first-order segments shows that different magmatic budgets among first-order segments are expressed as different levels of hydrothermal spatial density. This correlation is absent among second-order segments. Eighty-five percent of the plumes occur in eight clusters totaling ∼350 km. We hypothesize that these clusters are a minimum estimate of the length of axial melt lenses underlying this section of the SEIR.

Correlated patterns in hydrothermal plume distribution and apparent magmatic budget along 2500 km of the Southeast Indian Ridge

NASA Astrophysics Data System (ADS)

Baker, Edward T.; Hémond, Christophe; Briais, Anne; Maia, Marcia; Scheirer, Daniel S.; Walker, Sharon L.; Wang, Tingting; Chen, Yongshun John

2014-08-01

Multiple geological processes affect the distribution of hydrothermal venting along a mid-ocean ridge. Deciphering the role of a specific process is often frustrated by simultaneous changes in other influences. Here we take advantage of the almost constant spreading rate (65-71 mm/yr) along 2500 km of the Southeast Indian Ridge (SEIR) between 77°E and 99°E to examine the spatial density of hydrothermal venting relative to regional and segment-scale changes in the apparent magmatic budget. We use 227 vertical profiles of light backscatter and (on 41 profiles) oxidation-reduction potential along 27 first and second-order ridge segments on and adjacent to the Amsterdam-St. Paul (ASP) Plateau to map ph, the fraction of casts detecting a plume. At the regional scale, venting on the five segments crossing the magma-thickened hot spot plateau is almost entirely suppressed (ph = 0.02). Conversely, the combined ph (0.34) from all other segments follows the global trend of ph versus spreading rate. Off the ASP Plateau, multisegment trends in ph track trends in the regional axial depth, high where regional depth increases and low where it decreases. At the individual segment scale, a robust correlation between ph and cross-axis inflation for first-order segments shows that different magmatic budgets among first-order segments are expressed as different levels of hydrothermal spatial density. This correlation is absent among second-order segments. Eighty-five percent of the plumes occur in eight clusters totaling ˜350 km. We hypothesize that these clusters are a minimum estimate of the length of axial melt lenses underlying this section of the SEIR.

Variational Iterative Methods for Nonsymmetric Systems of Linear Equations.

DTIC Science & Technology

1981-08-01

With a third matrix-vector product, b(i) can be computed as i j ( ATAr i+l’pj)/ApjpApj), and the previous (Apj) need not be saved. Page 8 I OCR I Orthomin... Economics and Mathematical Systems, Volume 134, Springer-Verlag, Berlin, 1976. [51 Paul Concus, Gene H. Golub, and Dianne P. O’Leary. A generalized

Bio-Inspired Sensing and Display of Polarization Imagery

DTIC Science & Technology

2005-07-17

and weighting coefficients in this example. Panel 4D clearly shows a better visibility, feature extraction , and lesser effect from the background...of linear polarization. Panel E represents the segmentation of the degree of linear polarization, and then Panel F shows the extracted segment with...polarization, and Panel F shows the segment extraction with the finger print selected. Panel G illustrates the application of Canny edge detection to

Rod-Coil Block Polyimide Copolymers

NASA Technical Reports Server (NTRS)

Meador, Mary Ann B. (Inventor); Kinder, James D. (Inventor)

2005-01-01

This invention is a series of rod-coil block polyimide copolymers that are easy to fabricate into mechanically resilient films with acceptable ionic or protonic conductivity at a variety of temperatures. The copolymers consist of short-rigid polyimide rod segments alternating with polyether coil segments. The rods and coil segments can be linear, branched or mixtures of linear and branched segments. The highly incompatible rods and coil segments phase separate, providing nanoscale channels for ion conduction. The polyimide segments provide dimensional and mechanical stability and can be functionalized in a number of ways to provide specialized functions for a given application. These rod-coil black polyimide copolymers are particularly useful in the preparation of ion conductive membranes for use in the manufacture of fuel cells and lithium based polymer batteries.

Effects of Ga substitution on the structural and magnetic properties of half metallic Fe2MnSi Heusler compound

NASA Astrophysics Data System (ADS)

Pedro, S. S.; Caraballo Vivas, R. J.; Andrade, V. M.; Cruz, C.; Paixão, L. S.; Contreras, C.; Costa-Soares, T.; Caldeira, L.; Coelho, A. A.; Carvalho, A. Magnus G.; Rocco, D. L.; Reis, M. S.

2015-01-01

The so-called half-metallic magnets have been proposed as good candidates for spintronic applications due to the feature of exhibiting a hundred percent spin polarization at the Fermi level. Such materials follow the Slater-Pauling rule, which relates the magnetic moment with the valence electrons in the system. In this paper, we study the bulk polycrystalline half-metallic Fe2MnSi Heusler compound replacing Si by Ga to determine how the Ga addition changes the magnetic, the structural, and the half-metal properties of this compound. The material does not follow the Slater-Pauling rule, probably due to a minor structural disorder degree in the system, but a linear dependence on the magnetic transition temperature with the valence electron number points to the half-metallic behavior of this compound.

Proposed Advance Measures Flood Control Project Hampton Township, Bay County, Michigan. Intensive Archaeological Survey. Volume 1,

DTIC Science & Technology

1987-08-01

S _6RIDGE 559ROAD S99 * Radio ToW~ a (W BC ------ ed itnpiton01. UI PEN ’- EE- .ALn7 I 31 tt ,5 (’I b h a"" ,,.... .- O.CORRIDOR SEGMENT 3 , ,17.- 1A...followed in 1857. Gerardus Vennix and Henry Rooiskers, Hollan- ders, came in 1858 along with Louis Gullette of Mt. Clemens , Michigan, Patrick Bergen...quality chert or agate. Type identity is unknown to Mr. Neering. The cache was found by Paul Schmidt , another local HAS member. Mr. Neering advises me

An automatic and accurate method of full heart segmentation from CT image based on linear gradient model

NASA Astrophysics Data System (ADS)

Yang, Zili

2017-07-01

Heart segmentation is an important auxiliary method in the diagnosis of many heart diseases, such as coronary heart disease and atrial fibrillation, and in the planning of tumor radiotherapy. Most of the existing methods for full heart segmentation treat the heart as a whole part and cannot accurately extract the bottom of the heart. In this paper, we propose a new method based on linear gradient model to segment the whole heart from the CT images automatically and accurately. Twelve cases were tested in order to test this method and accurate segmentation results were achieved and identified by clinical experts. The results can provide reliable clinical support.

Element for use in an inductive coupler for downhole components

DOEpatents

Hall, David R [Provo, UT; Fox, Joe [Spanish Fork, UT

2009-03-31

An element for use in an inductive coupler for downhole components comprises an annular housing having a generally circular recess. The element further comprises a plurality of generally linear, magnetically conductive segments. Each segment includes a bottom portion, an inner wall portion, and an outer wall portion. The portions together define a generally linear trough from a first end to a second end of each segment. The segments are arranged adjacent to each other within the housing recess to form a generally circular trough. The ends of at least half of the segments are shaped such that the first end of one of the segments is complementary in form to the second end of an adjacent segment. In one embodiment, all of the ends are angled. Preferably, the first ends are angled with the same angle and the second ends are angled with the complementary angle.

Classification of arterial and venous cerebral vasculature based on wavelet postprocessing of CT perfusion data.

PubMed

Havla, Lukas; Schneider, Moritz J; Thierfelder, Kolja M; Beyer, Sebastian E; Ertl-Wagner, Birgit; Reiser, Maximilian F; Sommer, Wieland H; Dietrich, Olaf

2016-02-01

The purpose of this study was to propose and evaluate a new wavelet-based technique for classification of arterial and venous vessels using time-resolved cerebral CT perfusion data sets. Fourteen consecutive patients (mean age 73 yr, range 17-97) with suspected stroke but no pathology in follow-up MRI were included. A CT perfusion scan with 32 dynamic phases was performed during intravenous bolus contrast-agent application. After rigid-body motion correction, a Paul wavelet (order 1) was used to calculate voxelwise the wavelet power spectrum (WPS) of each attenuation-time course. The angiographic intensity A was defined as the maximum of the WPS, located at the coordinates T (time axis) and W (scale/width axis) within the WPS. Using these three parameters (A, T, W) separately as well as combined by (1) Fisher's linear discriminant analysis (FLDA), (2) logistic regression (LogR) analysis, or (3) support vector machine (SVM) analysis, their potential to classify 18 different arterial and venous vessel segments per subject was evaluated. The best vessel classification was obtained using all three parameters A and T and W [area under the curve (AUC): 0.953 with FLDA and 0.957 with LogR or SVM]. In direct comparison, the wavelet-derived parameters provided performance at least equal to conventional attenuation-time-course parameters. The maximum AUC obtained from the proposed wavelet parameters was slightly (although not statistically significantly) higher than the maximum AUC (0.945) obtained from the conventional parameters. A new method to classify arterial and venous cerebral vessels with high statistical accuracy was introduced based on the time-domain wavelet transform of dynamic CT perfusion data in combination with linear or nonlinear multidimensional classification techniques.

Effects of Ga substitution on the structural and magnetic properties of half metallic Fe{sub 2}MnSi Heusler compound

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pedro, S. S., E-mail: sandrapedro@uerj.br; Caraballo Vivas, R. J.; Andrade, V. M.

2015-01-07

The so-called half-metallic magnets have been proposed as good candidates for spintronic applications due to the feature of exhibiting a hundred percent spin polarization at the Fermi level. Such materials follow the Slater-Pauling rule, which relates the magnetic moment with the valence electrons in the system. In this paper, we study the bulk polycrystalline half-metallic Fe{sub 2}MnSi Heusler compound replacing Si by Ga to determine how the Ga addition changes the magnetic, the structural, and the half-metal properties of this compound. The material does not follow the Slater-Pauling rule, probably due to a minor structural disorder degree in the system,more » but a linear dependence on the magnetic transition temperature with the valence electron number points to the half-metallic behavior of this compound.« less

Efficient Third-Order Distributed Feedback Laser with Enhanced Beam Pattern

NASA Technical Reports Server (NTRS)

Hu, Qing (Inventor); Lee, Alan Wei Min (Inventor); Kao, Tsung-Yu (Inventor)

2015-01-01

A third-order distributed feedback laser has an active medium disposed on a substrate as a linear array of segments having a series of periodically spaced interstices therebetween and a first conductive layer disposed on a surface of the active medium on each of the segments and along a strip from each of the segments to a conductive electrical contact pad for application of current along a path including the active medium. Upon application of a current through the active medium, the active medium functions as an optical waveguide, and there is established an alternating electric field, at a THz frequency, both in the active medium and emerging from the interstices. Spacing of adjacent segments is approximately half of a wavelength of the THz frequency in free space or an odd integral multiple thereof, so that the linear array has a coherence length greater than the length of the linear array.

Mechanically Resilient Polymeric Films Doped with a Lithium Compound

NASA Technical Reports Server (NTRS)

Meador, Mary Ann B. (Inventor); Kinder, James D. (Inventor)

2005-01-01

This invention is a series of mechanically resilient polymeric films, comprising rod-coil block polyimide copolymers, which are doped with a lithium compound providing lithium ion conductivity, that are easy to fabricate into mechanically resilient films with acceptable ionic or protonic conductivity at a variety of temperatures. The copolymers consists of short-rigid polyimide rod segments alternating with polyether coil segments. The rods and coil segments can be linear, branched or mixtures of linear and branched segments. The highly incompatible rods and coil segments phase separate, providing nanoscale channels for ion conduction. The polyimide segments provide dimensional and mechanical stability and can be functionalized in a number of ways to provide specialized functions for a given application. These rod-coil black polyimide copolymers are particularly useful in the preparation of ion conductive membranes for use in the manufacture of fuel cells and lithium based polymer batteries.

Paul Fleming | NREL

Science.gov Websites

Paul Fleming Photo of Paul Fleming Paul Fleming Researcher IV-Control Engineering Paul.Fleming analysis of control systems for wind energy. Paul co-designed the control system used for field testing of advanced control systems on the CARTs, located at the NWTC. Since joining NREL, he has researched topics

Paul Veers | NREL

Science.gov Websites

Veers Photo of Paul Veers Paul Veers Group Research Manager III-Mechanical Engineering Paul.Veers @nrel.gov | 303-384-7197 Paul Veers is the Chief Engineer at the NWTC and represents NREL on DOE's Staff at Sandia National Laboratories. Paul has authored over 70 articles, papers, book chapters, and

Paul Denholm | NREL

Science.gov Websites

Denholm Photo of Paul Denholm Paul Denholm Principal Energy Analyst Paul.Denholm@nrel.gov | 303-384 -7488 Paul Denholm is a member of the Grid Systems Analysis Group in the Strategic Energy Analysis Center. Paul is a leading researcher in grid applications for energy storage and solar energy. He

Linear test bed. Volume 1: Test bed no. 1. [aerospike test bed with segmented combustor

NASA Technical Reports Server (NTRS)

1972-01-01

The Linear Test Bed program was to design, fabricate, and evaluation test an advanced aerospike test bed which employed the segmented combustor concept. The system is designated as a linear aerospike system and consists of a thrust chamber assembly, a power package, and a thrust frame. It was designed as an experimental system to demonstrate the feasibility of the linear aerospike-segmented combustor concept. The overall dimensions are 120 inches long by 120 inches wide by 96 inches in height. The propellants are liquid oxygen/liquid hydrogen. The system was designed to operate at 1200-psia chamber pressure, at a mixture ratio of 5.5. At the design conditions, the sea level thrust is 200,000 pounds. The complete program including concept selection, design, fabrication, component test, system test, supporting analysis and posttest hardware inspection is described.

STS-113 crew during M-113 armored personnel carrier training

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- STS-113 Mission Specialist Michael Lopez-Alegria concentrates on driving an M-113 armored personnel carrier during emergency egress training at the pad. He is accompanied by (far left) Mission Specialist John Herrington and Commander James Wetherbee. Behind Lopez-Alegria is Pilot Paul Lockhart. The crew is preparing for the mission aboard Space Shuttle Endeavour, which is scheduled to launch Nov. 10, by taking part in Terminal Countdown Demonstration Test activities. The TCDT includes a simulated launch countdown.. The primary payloads on mission STS-113 are the first port truss segment, P1, and the Crew and Equipment Translation Aid (CETA) Cart B. Once delivered, the P1 truss will remain stowed until flight 12A.1 in 2003 when it will be attached to the central truss segment, S0, on the Space Station. Also onboard Space Shuttle Endeavour will be the Expedition 6 crew who will replace Expedition 5, returning to Earth after 4 months.

An image segmentation method for apple sorting and grading using support vector machine and Otsu's method

USDA-ARS?s Scientific Manuscript database

Segmentation is the first step in image analysis to subdivide an image into meaningful regions. The segmentation result directly affects the subsequent image analysis. The objective of the research was to develop an automatic adjustable algorithm for segmentation of color images, using linear suppor...

St Paul fracture zone intratransform ridge basalts (Equatorial Atlantic): Insight within the mantle source diversity

NASA Astrophysics Data System (ADS)

Hemond, C.; Brunelli, D.; Maia, M.; Prigent, S.; Sichel, S. E.

2017-12-01

The St Paul Transform System offsets by 630 km the Equatorial Mid Atlantic Ridge at 1° N. It consists of four Major faults separating three intra transform ridge axes. Volcanic glassy samples were collected inside two intratransform ridge (ITR) segments during the COLMEIA cruise (Maia et al ; 2016) and samples from the third ITR available from a previous cruise ST PAUL (Hékinian et al. 2000). Major, trace elements and Hf, Pb, Sr and Nd isotopes were determined on selected hand picked glass chips. Few glassy samples recovered and analysed from abyssal hill samples open a time window of about 4.5 million years in the chemistry of the northern ITR. Results show that all samples are basaltic in composition but trace elements display contrasting images for the three ITR. The northern ITR samples are all light REE and highly incompatible enriched and are E-MORB; the central ITR samples display rather flat REE pattern with a level on enrichment of the HREE higher than the other two ITR and are T-MORB. Southern ITR samples are more heterogeneous N-MORB to T-MORB with a lower level of HREE. Isotopes reveal that the ITRs sample distinct mantle sources. In various isotope plans, the northern ITR samples plot together with published results from the MAR directly north of the St Paul F.Z. Therefore they exhibit some flavor of the Sierra Leone hotspot interacting with the MAR at 1.7°N. Central and southern ITR samples have very distinct composition from the northern ITR but resemble each other. However, for identical 206Pb/204Pb ratios, central ITR has slightly but significantly higher 207Pb/204Pb and 208Pb/204Pb, also higher 143Nd/144Nd for a given 87Sr/86Sr. Southern ITR is in chemical continuity of the MAR southward. So that central ITR samples display a rather specific composition. Off axis samples corresponding to the activity of the northern ITR up to 4.6 m.y. show that the hotspot contribution was even bigger on the spreading axis than today and might be fading with time as the MAR gets away from the Hotspot. It remains to explain how the flow of enriched material derived from the Sierra Leone hotspot passed through the large transform fault that limits the St Paul zone to the north. It is also of interest to explain the peculiar compositions of the central ITR samples that reflect neither the northern adjacent MAR composition nor the southern one.

Segmentation of white blood cells and comparison of cell morphology by linear and naïve Bayes classifiers.

PubMed

Prinyakupt, Jaroonrut; Pluempitiwiriyawej, Charnchai

2015-06-30

Blood smear microscopic images are routinely investigated by haematologists to diagnose most blood diseases. However, the task is quite tedious and time consuming. An automatic detection and classification of white blood cells within such images can accelerate the process tremendously. In this paper we propose a system to locate white blood cells within microscopic blood smear images, segment them into nucleus and cytoplasm regions, extract suitable features and finally, classify them into five types: basophil, eosinophil, neutrophil, lymphocyte and monocyte. Two sets of blood smear images were used in this study's experiments. Dataset 1, collected from Rangsit University, were normal peripheral blood slides under light microscope with 100× magnification; 555 images with 601 white blood cells were captured by a Nikon DS-Fi2 high-definition color camera and saved in JPG format of size 960 × 1,280 pixels at 15 pixels per 1 μm resolution. In dataset 2, 477 cropped white blood cell images were downloaded from CellaVision.com. They are in JPG format of size 360 × 363 pixels. The resolution is estimated to be 10 pixels per 1 μm. The proposed system comprises a pre-processing step, nucleus segmentation, cell segmentation, feature extraction, feature selection and classification. The main concept of the segmentation algorithm employed uses white blood cell's morphological properties and the calibrated size of a real cell relative to image resolution. The segmentation process combined thresholding, morphological operation and ellipse curve fitting. Consequently, several features were extracted from the segmented nucleus and cytoplasm regions. Prominent features were then chosen by a greedy search algorithm called sequential forward selection. Finally, with a set of selected prominent features, both linear and naïve Bayes classifiers were applied for performance comparison. This system was tested on normal peripheral blood smear slide images from two datasets. Two sets of comparison were performed: segmentation and classification. The automatically segmented results were compared to the ones obtained manually by a haematologist. It was found that the proposed method is consistent and coherent in both datasets, with dice similarity of 98.9 and 91.6% for average segmented nucleus and cell regions, respectively. Furthermore, the overall correction rate in the classification phase is about 98 and 94% for linear and naïve Bayes models, respectively. The proposed system, based on normal white blood cell morphology and its characteristics, was applied to two different datasets. The results of the calibrated segmentation process on both datasets are fast, robust, efficient and coherent. Meanwhile, the classification of normal white blood cells into five types shows high sensitivity in both linear and naïve Bayes models, with slightly better results in the linear classifier.

76 FR 37194 - Surety Companies Acceptable on Federal Bonds; Change in State of Incorportation, Business Address...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... State of Incorportation, Business Address and Phone; St. Paul Fire and Marine Insurance Company; St. Paul Guardian Insurance Company; St. Paul Mercury Insurance Company AGENCY: Financial Management... that St. Paul Fire and Marine Insurance Company (24767), St. Paul Guardian Insurance Company (24775...

Analysis of continuously rotating quadrupole focusing channels using generalized Courant-Snyder theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chung, Moses; Qin, Hong; Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026

2013-08-15

By extending the recently developed generalized Courant-Snyder theory for coupled transverse beam dynamics, we have constructed the Gaussian beam distribution and its projections with arbitrary mode emittance ratios. The new formulation has been applied to a continuously rotating quadrupole focusing channel because the basic properties of this channel are known theoretically and could also be investigated experimentally in a compact setup such as the linear Paul trap configuration. The new formulation retains a remarkably similar mathematical structure to the original Courant-Snyder theory, and thus, provides a powerful theoretical tool to investigate coupled transverse beam dynamics in general and more complexmore » linear focusing channels.« less

Individual muscle segmentation in MR images: A 3D propagation through 2D non-linear registration approaches.

PubMed

Ogier, Augustin; Sdika, Michael; Foure, Alexandre; Le Troter, Arnaud; Bendahan, David

2017-07-01

Manual and automated segmentation of individual muscles in magnetic resonance images have been recognized as challenging given the high variability of shapes between muscles and subjects and the discontinuity or lack of visible boundaries between muscles. In the present study, we proposed an original algorithm allowing a semi-automatic transversal propagation of manually-drawn masks. Our strategy was based on several ascending and descending non-linear registration approaches which is similar to the estimation of a Lagrangian trajectory applied to manual masks. Using several manually-segmented slices, we have evaluated our algorithm on the four muscles of the quadriceps femoris group. We mainly showed that our 3D propagated segmentation was very accurate with an averaged Dice similarity coefficient value higher than 0.91 for the minimal manual input of only two manually-segmented slices.

Primal/dual linear programming and statistical atlases for cartilage segmentation.

PubMed

Glocker, Ben; Komodakis, Nikos; Paragios, Nikos; Glaser, Christian; Tziritas, Georgios; Navab, Nassir

2007-01-01

In this paper we propose a novel approach for automatic segmentation of cartilage using a statistical atlas and efficient primal/dual linear programming. To this end, a novel statistical atlas construction is considered from registered training examples. Segmentation is then solved through registration which aims at deforming the atlas such that the conditional posterior of the learned (atlas) density is maximized with respect to the image. Such a task is reformulated using a discrete set of deformations and segmentation becomes equivalent to finding the set of local deformations which optimally match the model to the image. We evaluate our method on 56 MRI data sets (28 used for the model and 28 used for evaluation) and obtain a fully automatic segmentation of patella cartilage volume with an overlap ratio of 0.84 with a sensitivity and specificity of 94.06% and 99.92%, respectively.

Relaxation dynamics of internal segments of DNA chains in nanochannels

NASA Astrophysics Data System (ADS)

Jain, Aashish; Muralidhar, Abhiram; Dorfman, Kevin; Dorfman Group Team

We will present relaxation dynamics of internal segments of a DNA chain confined in nanochannel. The results have direct application in genome mapping technology, where long DNA molecules containing sequence-specific fluorescent probes are passed through an array of nanochannels to linearize them, and then the distances between these probes (the so-called ``DNA barcode'') are measured. The relaxation dynamics of internal segments set the experimental error due to dynamic fluctuations. We developed a multi-scale simulation algorithm, combining a Pruned-Enriched Rosenbluth Method (PERM) simulation of a discrete wormlike chain model with hard spheres with Brownian dynamics (BD) simulations of a bead-spring chain. Realistic parameters such as the bead friction coefficient and spring force law parameters are obtained from PERM simulations and then mapped onto the bead-spring model. The BD simulations are carried out to obtain the extension autocorrelation functions of various segments, which furnish their relaxation times. Interestingly, we find that (i) corner segments relax faster than the center segments and (ii) relaxation times of corner segments do not depend on the contour length of DNA chain, whereas the relaxation times of center segments increase linearly with DNA chain size.

Planning and Problem Solving

DTIC Science & Technology

1982-10-01

Artificial Intelig ~ence (Vol. III, edited by Paul R. Cohen and’ Edward A.. Feigenbaum)’, The chapter was written B’ Paul Cohen, with contributions... Artificial Intelligence (Vol. III, edited by Paul R. Cohen and EdWard A. Feigenbaum). The chapter was written by Paul R. Cohen, with contributions by Stephen...Wheevoats"EntermdI’ Planning and Problem ’Solving by Paul R. Cohen Chaptb-rXV-of Volumec III’of the Handbook of Artificial Intelligence edited by Paul R

Segmental intelligibility of synthetic speech produced by rule.

PubMed

Logan, J S; Greene, B G; Pisoni, D B

1989-08-01

This paper reports the results of an investigation that employed the modified rhyme test (MRT) to measure the segmental intelligibility of synthetic speech generated automatically by rule. Synthetic speech produced by ten text-to-speech systems was studied and compared to natural speech. A variation of the standard MRT was also used to study the effects of response set size on perceptual confusions. Results indicated that the segmental intelligibility scores formed a continuum. Several systems displayed very high levels of performance that were close to or equal to scores obtained with natural speech; other systems displayed substantially worse performance compared to natural speech. The overall performance of the best system, DECtalk--Paul, was equivalent to the data obtained with natural speech for consonants in syllable-initial position. The findings from this study are discussed in terms of the use of a set of standardized procedures for measuring intelligibility of synthetic speech under controlled laboratory conditions. Recent work investigating the perception of synthetic speech under more severe conditions in which greater demands are made on the listener's processing resources is also considered. The wide range of intelligibility scores obtained in the present study demonstrates important differences in perception and suggests that not all synthetic speech is perceptually equivalent to the listener.

Segmental intelligibility of synthetic speech produced by rule

PubMed Central

Logan, John S.; Greene, Beth G.; Pisoni, David B.

2012-01-01

This paper reports the results of an investigation that employed the modified rhyme test (MRT) to measure the segmental intelligibility of synthetic speech generated automatically by rule. Synthetic speech produced by ten text-to-speech systems was studied and compared to natural speech. A variation of the standard MRT was also used to study the effects of response set size on perceptual confusions. Results indicated that the segmental intelligibility scores formed a continuum. Several systems displayed very high levels of performance that were close to or equal to scores obtained with natural speech; other systems displayed substantially worse performance compared to natural speech. The overall performance of the best system, DECtalk—Paul, was equivalent to the data obtained with natural speech for consonants in syllable-initial position. The findings from this study are discussed in terms of the use of a set of standardized procedures for measuring intelligibility of synthetic speech under controlled laboratory conditions. Recent work investigating the perception of synthetic speech under more severe conditions in which greater demands are made on the listener’s processing resources is also considered. The wide range of intelligibility scores obtained in the present study demonstrates important differences in perception and suggests that not all synthetic speech is perceptually equivalent to the listener. PMID:2527884

RF Photonic Link Test Bed

DTIC Science & Technology

2004-09-01

TEST BED 6. AUTHOR(S) 1Lt Charles Ware, Paul Payson, Richard Michalak and George Brost 5 . FUNDING NUMBERS C - N/A PE - 62204F...modulator [ 5 ]. As can be deduced from the above equation, biasing the modulator at Vπ/2, or quadrature, allows the device to operate in the most linear...is desirable to have access to the secure surveillance facility added to your 5 RRS badge, since room F-251 is in this area. This allows unescorted

Perception of synthetic speech produced automatically by rule: Intelligibility of eight text-to-speech systems.

PubMed

Greene, Beth G; Logan, John S; Pisoni, David B

1986-03-01

We present the results of studies designed to measure the segmental intelligibility of eight text-to-speech systems and a natural speech control, using the Modified Rhyme Test (MRT). Results indicated that the voices tested could be grouped into four categories: natural speech, high-quality synthetic speech, moderate-quality synthetic speech, and low-quality synthetic speech. The overall performance of the best synthesis system, DECtalk-Paul, was equivalent to natural speech only in terms of performance on initial consonants. The findings are discussed in terms of recent work investigating the perception of synthetic speech under more severe conditions. Suggestions for future research on improving the quality of synthetic speech are also considered.

Tortuosity of lightning return stroke channels

NASA Technical Reports Server (NTRS)

Levine, D. M.; Gilson, B.

1984-01-01

Data obtained from photographs of lightning are presented on the tortuosity of return stroke channels. The data were obtained by making piecewise linear fits to the channels, and recording the cartesian coordinates of the ends of each linear segment. The mean change between ends of the segments was nearly zero in the horizontal direction and was about eight meters in the vertical direction. Histograms of these changes are presented. These data were used to create model lightning channels and to predict the electric fields radiated during return strokes. This was done using a computer generated random walk in which linear segments were placed end-to-end to form a piecewise linear representation of the channel. The computer selected random numbers for the ends of the segments assuming a normal distribution with the measured statistics. Once the channels were simulated, the electric fields radiated during a return stroke were predicted using a transmission line model on each segment. It was found that realistic channels are obtained with this procedure, but only if the model includes two scales of tortuosity: fine scale irregularities corresponding to the local channel tortuosity which are superimposed on large scale horizontal drifts. The two scales of tortuosity are also necessary to obtain agreement between the electric fields computed mathematically from the simulated channels and the electric fields radiated from real return strokes. Without large scale drifts, the computed electric fields do not have the undulations characteristics of the data.

Phanerozoic geological evolution of the Equatorial Atlantic domain

NASA Astrophysics Data System (ADS)

Basile, Christophe; Mascle, Jean; Guiraud, René

2005-10-01

The Phanerozoic geological evolution of the Equatorial Atlantic domain has been controlled since the end of Early Cretaceous by the Romanche and Saint Paul transform faults. These faults did not follow the PanAfrican shear zones, but were surimposed on Palæozoic basins. From Neocomian to Barremian, the Central Atlantic rift propagated southward in Cassiporé and Marajó basins, and the South Atlantic rift propagated northward in Potiguar and Benue basins. During Aptian times, the Equatorial Atlantic transform domain appeared as a transfer zone between the northward propagating tip of South Atlantic and the Central Atlantic. Between the transform faults, oceanic accretion started during Late Aptian in small divergent segments, from south to north: Benin-Mundaú, deep Ivorian basin-Barreirinhas, Liberia-Cassiporé. From Late Aptian to Late Albian, the Togo-Ghana-Ceará basins appeared along the Romanche transform fault, and Côte d'Ivoire-Parà-Maranhão basins along Saint Paul transform fault. They were rapidly subsiding in intra-continental settings. During Late Cretaceous, these basins became active transform continental margins, and passive margins since Santonian times. In the same time, the continental edge uplifted leading either to important erosion on the shelf or to marginal ridges parallel to the transform faults in deeper settings.

Automatic segmentation of vessels in in-vivo ultrasound scans

NASA Astrophysics Data System (ADS)

Tamimi-Sarnikowski, Philip; Brink-Kjær, Andreas; Moshavegh, Ramin; Arendt Jensen, Jørgen

2017-03-01

Ultrasound has become highly popular to monitor atherosclerosis, by scanning the carotid artery. The screening involves measuring the thickness of the vessel wall and diameter of the lumen. An automatic segmentation of the vessel lumen, can enable the determination of lumen diameter. This paper presents a fully automatic segmentation algorithm, for robustly segmenting the vessel lumen in longitudinal B-mode ultrasound images. The automatic segmentation is performed using a combination of B-mode and power Doppler images. The proposed algorithm includes a series of preprocessing steps, and performs a vessel segmentation by use of the marker-controlled watershed transform. The ultrasound images used in the study were acquired using the bk3000 ultrasound scanner (BK Ultrasound, Herlev, Denmark) with two transducers "8L2 Linear" and "10L2w Wide Linear" (BK Ultrasound, Herlev, Denmark). The algorithm was evaluated empirically and applied to a dataset of in-vivo 1770 images recorded from 8 healthy subjects. The segmentation results were compared to manual delineation performed by two experienced users. The results showed a sensitivity and specificity of 90.41+/-11.2 % and 97.93+/-5.7% (mean+/-standard deviation), respectively. The amount of overlap of segmentation and manual segmentation, was measured by the Dice similarity coefficient, which was 91.25+/-11.6%. The empirical results demonstrated the feasibility of segmenting the vessel lumen in ultrasound scans using a fully automatic algorithm.

Development of a piecewise linear omnidirectional 3D image registration method

NASA Astrophysics Data System (ADS)

Bae, Hyunsoo; Kang, Wonjin; Lee, SukGyu; Kim, Youngwoo

2016-12-01

This paper proposes a new piecewise linear omnidirectional image registration method. The proposed method segments an image captured by multiple cameras into 2D segments defined by feature points of the image and then stitches each segment geometrically by considering the inclination of the segment in the 3D space. Depending on the intended use of image registration, the proposed method can be used to improve image registration accuracy or reduce the computation time in image registration because the trade-off between the computation time and image registration accuracy can be controlled for. In general, nonlinear image registration methods have been used in 3D omnidirectional image registration processes to reduce image distortion by camera lenses. The proposed method depends on a linear transformation process for omnidirectional image registration, and therefore it can enhance the effectiveness of the geometry recognition process, increase image registration accuracy by increasing the number of cameras or feature points of each image, increase the image registration speed by reducing the number of cameras or feature points of each image, and provide simultaneous information on shapes and colors of captured objects.

CLASSICAL AREAS OF PHENOMENOLOGY: Study on the design and Zernike aberrations of a segmented mirror telescope

NASA Astrophysics Data System (ADS)

Jiang, Zhen-Yu; Li, Lin; Huang, Yi-Fan

2009-07-01

The segmented mirror telescope is widely used. The aberrations of segmented mirror systems are different from single mirror systems. This paper uses the Fourier optics theory to analyse the Zernike aberrations of segmented mirror systems. It concludes that the Zernike aberrations of segmented mirror systems obey the linearity theorem. The design of a segmented space telescope and segmented schemes are discussed, and its optical model is constructed. The computer simulation experiment is performed with this optical model to verify the suppositions. The experimental results confirm the correctness of the model.

Pondering the procephalon: the segmental origin of the labrum.

PubMed

Haas, M S; Brown, S J; Beeman, R W

2001-02-01

With accumulating evidence for the appendicular nature of the labrum, the question of its actual segmental origin remains. Two existing insect head segmentation models, the linear and S-models, are reviewed, and a new model introduced. The L-/Bent-Y model proposes that the labrum is a fusion of the appendage endites of the intercalary segment and that the stomodeum is tightly integrated into this segment. This model appears to explain a wider variety of insect head segmentation phenomena. Embryological, histological, neurological and molecular evidence supporting the new model is reviewed.

Electronegativity Equalization with Pauling Units.

ERIC Educational Resources Information Center

Bratsch, Steven G.

1984-01-01

Discusses electronegativity equalization using Pauling units. Although Pauling has qualitatively defined electronegativity as the power of an atom in a molecule to attract electrons to itself, Pauling electronegativities are treated in this paper as prebonded, isolated-atom quantities. (JN)

When syntax meets action: Brain potential evidence of overlapping between language and motor sequencing.

PubMed

Casado, Pilar; Martín-Loeches, Manuel; León, Inmaculada; Hernández-Gutiérrez, David; Espuny, Javier; Muñoz, Francisco; Jiménez-Ortega, Laura; Fondevila, Sabela; de Vega, Manuel

2018-03-01

This study aims to extend the embodied cognition approach to syntactic processing. The hypothesis is that the brain resources to plan and perform motor sequences are also involved in syntactic processing. To test this hypothesis, Event-Related brain Potentials (ERPs) were recorded while participants read sentences with embedded relative clauses, judging for their acceptability (half of the sentences contained a subject-verb morphosyntactic disagreement). The sentences, previously divided into three segments, were self-administered segment-by-segment in two different sequential manners: linear or non-linear. Linear self-administration consisted of successively pressing three buttons with three consecutive fingers in the right hand, while non-linear self-administration implied the substitution of the finger in the middle position by the right foot. Our aim was to test whether syntactic processing could be affected by the manner the sentences were self-administered. Main results revealed that the ERPs LAN component vanished whereas the P600 component increased in response to incorrect verbs, for non-linear relative to linear self-administration. The LAN and P600 components reflect early and late syntactic processing, respectively. Our results convey evidence that language syntactic processing and performing non-linguistic motor sequences may share resources in the human brain. Copyright © 2017 Elsevier Ltd. All rights reserved.

Transpressive mantle uplift at large offset oceanic transform faults

NASA Astrophysics Data System (ADS)

Maia, M.; Briais, A.; Brunelli, D.; Ligi, M.; Sichel, S. E.; Campos, T.

2017-12-01

Large-offset transform faults deform due to changes in plate motions and local processes. At the St. Paul transform, in the Equatorial Atlantic, a large body of ultramafic rocks composed of variably serpentinized and mylonitized peridotites is presently being tectonically uplifted. We recently discovered that the origin of the regional mantle uplift is linked to long-standing compressive stresses along the transform fault (1). A positive flower structure, mainly made of mylonitized mantle rocks, can be recognized on the 200 km large push-up ridge. Compressive earthquakes mechanisms reveal seismically active thrust faults on the southern flank of the ridge . The regional transpressive stress field affects a large portion of the ridge segment south of the transform, as revealed by the presence of faults and dykes striking obliquely to the direction of the central ridge axis. A smaller thrust, affecting recent sediments, was mapped south of this segment, suggesting a regional active compressive stress field. The transpressive stress field is interpreted to derive from the propagation of the Mid-Atlantic Ridge (MAR) segment into the transform domain as a response to the enhanced melt supply at the ridge axis. The propagation forced the migration and segmentation of the transform fault southward and the formation of restraining step-overs. The process started after a counterclockwise change in plate motion at 11 Ma initially resulting in extensive stress of the transform domain. A flexural transverse ridge formed in response. Shortly after plate reorganization, the MAR segment started to propagate southwards due to the interaction of the ridge and the Sierra Leone thermal anomaly. 1- Maia et al., 2016. Extreme mantle uplift and exhumation along a transpressive transform fault Nat. Geo. doi:10.1038/ngeo2759

North American Jumelage ’Type Systems’

DTIC Science & Technology

1993-10-20

Brian Howard bhoward~saul.cis.upenn.edu Doug Howe howegcs.cornell.edu Paul Jackson jacksongcs.cornell.edu Radhakrishnan Jagadeesan rj2Gdoc.imperial.ac.uk...Curry and Howard . They have shown that there exists an ’’isomorphism’’ between the terms of typed lambda calculus and the natural deduction proofs of...linear logic for computer science 3:05-3:30 Break 3:30-4:00 G. Bellin , Oxford University: Proof-nets without boxes and graphs with orientations 4:05-4:25 H

Nucleus detection using gradient orientation information and linear least squares regression

NASA Astrophysics Data System (ADS)

Kwak, Jin Tae; Hewitt, Stephen M.; Xu, Sheng; Pinto, Peter A.; Wood, Bradford J.

2015-03-01

Computerized histopathology image analysis enables an objective, efficient, and quantitative assessment of digitized histopathology images. Such analysis often requires an accurate and efficient detection and segmentation of histological structures such as glands, cells and nuclei. The segmentation is used to characterize tissue specimens and to determine the disease status or outcomes. The segmentation of nuclei, in particular, is challenging due to the overlapping or clumped nuclei. Here, we propose a nuclei seed detection method for the individual and overlapping nuclei that utilizes the gradient orientation or direction information. The initial nuclei segmentation is provided by a multiview boosting approach. The angle of the gradient orientation is computed and traced for the nuclear boundaries. Taking the first derivative of the angle of the gradient orientation, high concavity points (junctions) are discovered. False junctions are found and removed by adopting a greedy search scheme with the goodness-of-fit statistic in a linear least squares sense. Then, the junctions determine boundary segments. Partial boundary segments belonging to the same nucleus are identified and combined by examining the overlapping area between them. Using the final set of the boundary segments, we generate the list of seeds in tissue images. The method achieved an overall precision of 0.89 and a recall of 0.88 in comparison to the manual segmentation.

Integrated approach to multimodal media content analysis

NASA Astrophysics Data System (ADS)

Zhang, Tong; Kuo, C.-C. Jay

1999-12-01

In this work, we present a system for the automatic segmentation, indexing and retrieval of audiovisual data based on the combination of audio, visual and textural content analysis. The video stream is demultiplexed into audio, image and caption components. Then, a semantic segmentation of the audio signal based on audio content analysis is conducted, and each segment is indexed as one of the basic audio types. The image sequence is segmented into shots based on visual information analysis, and keyframes are extracted from each shot. Meanwhile, keywords are detected from the closed caption. Index tables are designed for both linear and non-linear access to the video. It is shown by experiments that the proposed methods for multimodal media content analysis are effective. And that the integrated framework achieves satisfactory results for video information filtering and retrieval.

Feasibility Study on a Segmented Ferrofluid Flow Linear Generator for Increasing the Time-Varying Magnetic Flux.

PubMed

Lee, Won-Ho; Lee, Se-Hee; Lee, Sangyoup; Lee, Jong-Chul

2018-09-01

Nanoparticles and nanofluids have been implemented in energy harvesting devices, and energy harvesting based on magnetic nanofluid flow was recently achieved by using a layer-built magnet and micro-bubble injection to induce a voltage on the order of 10-1 mV. However, this is not yet suitable for some commercial purpose. In order to further increase the amount of electric voltage and current from this energy harvesting the air bubbles must be segmented in the base fluid, and the magnetic flux of the segmented flow should be materially altered over time. The focus of this research is on the development of a segmented ferrofluid flow linear generator that would scavenge electrical power from waste heat. Experiments were conducted to obtain the induced voltage, which was generated by moving a ferrofluid-filled capsule inside a multi-turn coil. Computations were then performed to explain the fundamental physical basis of the motion of the segmented flow of the ferrofluids and the air-layers.

Quadrature amplitude modulation (QAM) using binary-driven coupling-modulated rings

NASA Astrophysics Data System (ADS)

Karimelahi, Samira; Sheikholeslami, Ali

2016-05-01

We propose and fully analyze a compact structure for DAC-free pure optical QAM modulation. The proposed structure is the first ring resonator-based DAC-free QAM modulator reported in the literature, to the best of our knowledge. The device consists of two segmented add-drop Mach Zehnder interferometer-assisted ring modulators (MZIARM) in an IQ configuration. The proposed architecture is investigated based on the parameters from SOI technology where various key design considerations are discussed. We have included the loss in the MZI arms in our analysis of phase and amplitude modulation using MZIARM for the first time and show that the imbalanced loss results in a phase error. The output level linearity is also studied for both QAM-16 and QAM-64 not only based on optimizing RF segment lengths but also by optimizing the number of segments. In QAM-16, linearity among levels is achievable with two segments while in QAM-64 an additional segment may be required.

New method for calculating a mathematical expression for streamflow recession

USGS Publications Warehouse

Rutledge, Albert T.

1991-01-01

An empirical method has been devised to calculate the master recession curve, which is a mathematical expression for streamflow recession during times of negligible direct runoff. The method is based on the assumption that the storage-delay factor, which is the time per log cycle of streamflow recession, varies linearly with the logarithm of streamflow. The resulting master recession curve can be nonlinear. The method can be executed by a computer program that reads a data file of daily mean streamflow, then allows the user to select several near-linear segments of streamflow recession. The storage-delay factor for each segment is one of the coefficients of the equation that results from linear least-squares regression. Using results for each recession segment, a mathematical expression of the storage-delay factor as a function of the log of streamflow is determined by linear least-squares regression. The master recession curve, which is a second-order polynomial expression for time as a function of log of streamflow, is then derived using the coefficients of this function.

Piecewise Linear-Linear Latent Growth Mixture Models with Unknown Knots

ERIC Educational Resources Information Center

Kohli, Nidhi; Harring, Jeffrey R.; Hancock, Gregory R.

2013-01-01

Latent growth curve models with piecewise functions are flexible and useful analytic models for investigating individual behaviors that exhibit distinct phases of development in observed variables. As an extension of this framework, this study considers a piecewise linear-linear latent growth mixture model (LGMM) for describing segmented change of…

Multi-segment detector array for hybrid reflection-mode ultrasound and optoacoustic tomography (Conference Presentation)

NASA Astrophysics Data System (ADS)

Merčep, Elena; Burton, Neal C.; Deán-Ben, Xosé Luís.; Razansky, Daniel

2017-02-01

The complementary contrast of the optoacoustic (OA) and pulse-echo ultrasound (US) modalities makes the combined usage of these imaging technologies highly advantageous. Due to the different physical contrast mechanisms development of a detector array optimally suited for both modalities is one of the challenges to efficient implementation of a single OA-US imaging device. We demonstrate imaging performance of the first hybrid detector array whose novel design, incorporating array segments of linear and concave geometry, optimally supports image acquisition in both reflection-mode ultrasonography and optoacoustic tomography modes. Hybrid detector array has a total number of 256 elements and three segments of different geometry and variable pitch size: a central 128-element linear segment with pitch of 0.25mm, ideally suited for pulse-echo US imaging, and two external 64-elements segments with concave geometry and 0.6mm pitch optimized for OA image acquisition. Interleaved OA and US image acquisition with up to 25 fps is facilitated through a custom-made multiplexer unit. Spatial resolution of the transducer was characterized in numerical simulations and validated in phantom experiments and comprises 230 and 300 μm in the respective OA and US imaging modes. Imaging performance of the multi-segment detector array was experimentally shown in a series of imaging sessions with healthy volunteers. Employing mixed array geometries allows at the same time achieving excellent OA contrast with a large field of view, and US contrast for complementary structural features with reduced side-lobes and improved resolution. The newly designed hybrid detector array that comprises segments of linear and concave geometries optimally fulfills requirements for efficient US and OA imaging and may expand the applicability of the developed hybrid OPUS imaging technology and accelerate its clinical translation.

40 CFR 81.27 - Minneapolis-St. Paul Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Minneapolis-St. Paul Intrastate Air... Air Quality Control Regions § 81.27 Minneapolis-St. Paul Intrastate Air Quality Control Region. The Minneapolis-St. Paul Intrastate Air Quality Control Region (Minnesota) consists of the territorial area...

75 FR 27494 - Proposed Amendment of Class E Airspace; Pauls Valley, OK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

... 0182; Airspace Docket No. 10-ASW-4] Proposed Amendment of Class E Airspace; Pauls Valley, OK AGENCY... action proposes to amend Class E airspace at Pauls Valley, OK. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Pauls Valley Municipal...

Perception of synthetic speech produced automatically by rule: Intelligibility of eight text-to-speech systems

PubMed Central

GREENE, BETH G.; LOGAN, JOHN S.; PISONI, DAVID B.

2012-01-01

We present the results of studies designed to measure the segmental intelligibility of eight text-to-speech systems and a natural speech control, using the Modified Rhyme Test (MRT). Results indicated that the voices tested could be grouped into four categories: natural speech, high-quality synthetic speech, moderate-quality synthetic speech, and low-quality synthetic speech. The overall performance of the best synthesis system, DECtalk-Paul, was equivalent to natural speech only in terms of performance on initial consonants. The findings are discussed in terms of recent work investigating the perception of synthetic speech under more severe conditions. Suggestions for future research on improving the quality of synthetic speech are also considered. PMID:23225916

James Webb Space Telescope optical simulation testbed III: first experimental results with linear-control alignment

NASA Astrophysics Data System (ADS)

Egron, Sylvain; Lajoie, Charles-Philippe; Leboulleux, Lucie; N'Diaye, Mamadou; Pueyo, Laurent; Choquet, Élodie; Perrin, Marshall D.; Ygouf, Marie; Michau, Vincent; Bonnefois, Aurélie; Fusco, Thierry; Escolle, Clément; Ferrari, Marc; Hugot, Emmanuel; Soummer, Rémi

2016-07-01

The James Webb Space Telescope (JWST) Optical Simulation Testbed (JOST) is a tabletop experiment designed to study wavefront sensing and control for a segmented space telescope, including both commissioning and maintenance activities. JOST is complementary to existing testbeds for JWST (e.g. the Ball Aerospace Testbed Telescope TBT) given its compact scale and flexibility, ease of use, and colocation at the JWST Science and Operations Center. The design of JOST reproduces the physics of JWST's three-mirror anastigmat (TMA) using three custom aspheric lenses. It provides similar quality image as JWST (80% Strehl ratio) over a field equivalent to a NIRCam module, but at 633 nm. An Iris AO segmented mirror stands for the segmented primary mirror of JWST. Actuators allow us to control (1) the 18 segments of the segmented mirror in piston, tip, tilt and (2) the second lens, which stands for the secondary mirror, in tip, tilt and x, y, z positions. We present the full linear control alignment infrastructure developed for JOST, with an emphasis on multi-field wavefront sensing and control. Our implementation of the Wavefront Sensing (WFS) algorithms using phase diversity is experimentally tested. The wavefront control (WFC) algorithms, which rely on a linear model for optical aberrations induced by small misalignments of the three lenses, are tested and validated on simulations.

Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography

NASA Astrophysics Data System (ADS)

Yong, Yan Ling; Tan, Li Kuo; McLaughlin, Robert A.; Chee, Kok Han; Liew, Yih Miin

2017-12-01

Intravascular optical coherence tomography (OCT) is an optical imaging modality commonly used in the assessment of coronary artery diseases during percutaneous coronary intervention. Manual segmentation to assess luminal stenosis from OCT pullback scans is challenging and time consuming. We propose a linear-regression convolutional neural network to automatically perform vessel lumen segmentation, parameterized in terms of radial distances from the catheter centroid in polar space. Benchmarked against gold-standard manual segmentation, our proposed algorithm achieves average locational accuracy of the vessel wall of 22 microns, and 0.985 and 0.970 in Dice coefficient and Jaccard similarity index, respectively. The average absolute error of luminal area estimation is 1.38%. The processing rate is 40.6 ms per image, suggesting the potential to be incorporated into a clinical workflow and to provide quantitative assessment of vessel lumen in an intraoperative time frame.

Meandering Musings by Linus Pauling: "American Scientists and the Spirit of the Frontier".

PubMed

Bause, George S

2016-04-01

Hoping to raise funds in 1975 for his namesake institute, Linus Pauling submitted to Esquire magazine a 32-page handwritten manuscript, "American Scientists and the Spirit of the Frontier." Angered when his submission for publication was declined, Pauling eventually gifted the original manuscript in 1986 to his friend, Linus Pauling Institute fundraiser Stephen Maddox, who would sell it in 2004 to the Wood Library-Museum of Anesthesiology. Published accurately here for the first time, the manuscript captures not only Pauling's sweeping metaphor of scientists as frontiersmen but also the creative process by which Pauling formulated his hydrate microcrystal theory of general anesthesia. Copyright © 2015 Elsevier Inc. All rights reserved.

Revisiting the phylogeny of Zoanthidea (Cnidaria: Anthozoa): Staggered alignment of hypervariable sequences improves species tree inference.

PubMed

Swain, Timothy D

2018-01-01

The recent rapid proliferation of novel taxon identification in the Zoanthidea has been accompanied by a parallel propagation of gene trees as a tool of species discovery, but not a corresponding increase in our understanding of phylogeny. This disparity is caused by the trade-off between the capabilities of automated DNA sequence alignment and data content of genes applied to phylogenetic inference in this group. Conserved genes or segments are easily aligned across the order, but produce poorly resolved trees; hypervariable genes or segments contain the evolutionary signal necessary for resolution and robust support, but sequence alignment is daunting. Staggered alignments are a form of phylogeny-informed sequence alignment composed of a mosaic of local and universal regions that allow phylogenetic inference to be applied to all nucleotides from both hypervariable and conserved gene segments. Comparisons between species tree phylogenies inferred from all data (staggered alignment) and hypervariable-excluded data (standard alignment) demonstrate improved confidence and greater topological agreement with other sources of data for the complete-data tree. This novel phylogeny is the most comprehensive to date (in terms of taxa and data) and can serve as an expandable tool for evolutionary hypothesis testing in the Zoanthidea. Spanish language abstract available in Text S1. Translation by L. O. Swain, DePaul University, Chicago, Illinois, 60604, USA. Copyright © 2017 Elsevier Inc. All rights reserved.

"Between the Heavens and the Earth": Narrating the Execution of Moses Paul

ERIC Educational Resources Information Center

Salyer, Matt

2012-01-01

The 1772 execution of the Mohegan sailor Moses Paul served as the occasion for Samson Occom's popular "Sermon," reprinted in numerous editions. Recent work by Ava Chamberlain seeks to recover Paul's version of events from contemporary court records. This article argues that Paul's "firsthand" account of the case and autobiographical narrative…

An apparatus for immersing trapped ions into an ultracold gas of neutral atoms

NASA Astrophysics Data System (ADS)

Schmid, Stefan; Härter, Arne; Frisch, Albert; Hoinka, Sascha; Denschlag, Johannes Hecker

2012-05-01

We describe a hybrid vacuum system in which a single ion or a well-defined small number of trapped ions (in our case Ba+ or Rb+) can be immersed into a cloud of ultracold neutral atoms (in our case Rb). This apparatus allows for the study of collisions and interactions between atoms and ions in the ultracold regime. Our setup is a combination of a Bose-Einstein condensation apparatus and a linear Paul trap. The main design feature of the apparatus is to first separate the production locations for the ion and the ultracold atoms and then to bring the two species together. This scheme has advantages in terms of stability and available access to the region where the atom-ion collision experiments are carried out. The ion and the atoms are brought together using a moving one-dimensional optical lattice transport which vertically lifts the atomic sample over a distance of 30 cm from its production chamber into the center of the Paul trap in another chamber. We present techniques to detect and control the relative position between the ion and the atom cloud.

Plane representations of graphs and visibility between parallel segments

NASA Astrophysics Data System (ADS)

Tamassia, R.; Tollis, I. G.

1985-04-01

Several layout compaction strategies for VLSI are based on the concept of visibility between parallel segments, where we say that two parallel segments of a given set are visible if they can be joined by a segment orthogonal to them, which does not intersect any other segment. This paper studies visibility representations of graphs, which are constructed by mapping vertices to horizontal segments, and edges to vertical segments drawn between visible vertex-segments. Clearly, every graph that admits such a representation must be a planar. The authors consider three types of visibility representations, and give complete characterizations of the classes of graphs that admit them. Furthermore, they present linear time algorithms for testing the existence of and constructing visibility representations of planar graphs.

75 FR 67303 - Determinations of Attainment by the Applicable Attainment Date for the Hayden, Nogales, Paul Spur...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... of Attainment by the Applicable Attainment Date for the Hayden, Nogales, Paul Spur/Douglas PM 10... proposes to determine that the Hayden, Nogales, and Paul Spur/Douglas nonattainment areas in Arizona... Hayden, Nogales and Paul Spur/Douglas nonattainment areas are not currently attaining the PM 10 standard...

77 FR 41168 - Marine Mammals; Subsistence Taking of Northern Fur Seals; St. Paul Island

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-12

... Mammals; Subsistence Taking of Northern Fur Seals; St. Paul Island AGENCY: National Marine Fisheries... taking of northern fur seals on St. Paul Island. St. Paul's petition requests that NMFS revise the... seals; take a total of up to 3,000 fur seals annually compared to 2,000 currently allowed, including up...

78 FR 46938 - St. Paul Park Refining Co. LLC v. Enbridge Pipelines (North Dakota) LLC; Notice of Complaint

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-02

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR13-28-000] St. Paul Park..., 2013, St. Paul Park Refining Co. LLC (Complainant) filed a formal complaint against Enbridge Pipelines... regulatory basis. St. Paul Park Refining Co. LLC certifies that copies of the complaint were served on the...

75 FR 34097 - Expansion of Foreign-Trade Zone 119; Minneapolis-St. Paul Area

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1684] Expansion of Foreign-Trade Zone 119; Minneapolis-St. Paul Area Pursuant to its authority under the Foreign-Trade Zones Act of June 18... Sites 7 and 8 in the Minneapolis-St. Paul area, adjacent to the Minneapolis-St. Paul Customs and Border...

"Dancing Cannot Start Too Soon": Spiritual Education in the Thought of Jean Paul Friedrich Richter

ERIC Educational Resources Information Center

Pridmore, John

2004-01-01

Johann Paul Friedrich Richter (1763-1825) adopted the pen-name "Jean Paul" in honour of Jean Jaques Rousseau. His "Levana or the doctrine of education" ("Levana oder Erziehlehre") was once a standard text and required reading in teacher education. Outside Germany the name of Jean Paul is now little known and the…

Ground Water Atlas of the United States: Segment 9, Iowa, Michigan, Minnesota, Wisconsin

USGS Publications Warehouse

Olcott, Perry G.

1992-01-01

Segment 9, which consists of Minnesota, Iowa, Wisconsin, and Michigan, abuts the Canadian border in the upper Midwest and lies adjacent to or surrounds four of the Great Lakes-Superior, Michigan, Huron, and Erie. Thousands of small to large lakes similar to the one shown in figure 1 dot the landscape, which is drained by numerous rivers and streams tributary primarily to the Mississippi River in the west and to the Great Lakes-St. Lawrence River system in the east. These abundant surface-water sources represent an ample supply of water to large users, such as the cities of Milwaukee, Wis., and Detroit, Mich. However, water stored in unconsolidated and consolidated sedimentary-rock aquifers that underlie the four States also is in abundant supply and is an economical source that can be used for nearly any purpose, usually with little or no treatment. In more than 95 percent of the four-State area, these aquifers supply water to a broad spectrum of consumers-from individual households to cities, such as St. Paul, Minn., Madison, Wis., and Lansing, Mich. These aquifers are the subject of this chapter. The geology and the hydrology of each of the principal aquifers are illustrated and discussed insofar as information was available from the literature. Hydrogeology, ground-water flow, availability and quality of water, and freshwater withdrawals from each of the aquifers are the principal subjects of discussion. Population in the four States is concentrated in the cities and is thinly dispersed in the broad agricultural areas of the States (fig. 2). Minneapolis-St. Paul, Minn., Des Moines, Iowa, Milwaukee and Madison, Wis., and Detroit and Lansing, Mich., are a few of the principal cities. Many of these cities and other large population centers represent areas of concentrated ground-water withdrawals. Precipitation is the source of all water in Segment 9. Average annual precipitation ranges from about 20 to 40 inches across the segment and generally increases from northwest to southeast (fig. 3). Precipitation is least in the northwestern part of the segment because of the orographic effect of the Rocky Mountains, which are hundreds of miles to the west. Annual precipitation in excess of 36 inches that falls south and east of Lakes Superior and Michigan (fig. 3) is a result of the prevailing westerly winds that evaporate moisture from the lakes; this moisture subsequently condenses and falls as precipitation over the land. Average annual runoff in rivers and streams (fig. 4) generally reflects average annual precipitation patterns (fig. 3). Runoff generally increases from less than 1 to more than 20 inches. Runoff also tends to be substantial downwind from Lakes Superior and Michigan. However, in no part of the segment does runoff exceed precipitation. Much of the water from precipitation is returned to the atmosphere by evapotranspiration-evaporation from the land and water surfaces, and transpiration by plants. Some of the water is stored in aquifers through ground-water recharge or is stored on the land surface in lakes, marshes, and reservoirs. Runoff represents water from precipitation that runs directly off the land surface to streams and water discharged to streams that was stored in lakes, marshes, reservoirs, or aquifers.

Saliency detection algorithm based on LSC-RC

NASA Astrophysics Data System (ADS)

Wu, Wei; Tian, Weiye; Wang, Ding; Luo, Xin; Wu, Yingfei; Zhang, Yu

2018-02-01

Image prominence is the most important region in an image, which can cause the visual attention and response of human beings. Preferentially allocating the computer resources for the image analysis and synthesis by the significant region is of great significance to improve the image area detecting. As a preprocessing of other disciplines in image processing field, the image prominence has widely applications in image retrieval and image segmentation. Among these applications, the super-pixel segmentation significance detection algorithm based on linear spectral clustering (LSC) has achieved good results. The significance detection algorithm proposed in this paper is better than the regional contrast ratio by replacing the method of regional formation in the latter with the linear spectral clustering image is super-pixel block. After combining with the latest depth learning method, the accuracy of the significant region detecting has a great promotion. At last, the superiority and feasibility of the super-pixel segmentation detection algorithm based on linear spectral clustering are proved by the comparative test.

Electronegativity determination of individual surface atoms by atomic force microscopy.

PubMed

Onoda, Jo; Ondráček, Martin; Jelínek, Pavel; Sugimoto, Yoshiaki

2017-04-26

Electronegativity is a fundamental concept in chemistry. Despite its importance, the experimental determination has been limited only to ensemble-averaged techniques. Here, we report a methodology to evaluate the electronegativity of individual surface atoms by atomic force microscopy. By measuring bond energies on the surface atoms using different tips, we find characteristic linear relations between the bond energies of different chemical species. We show that the linear relation can be rationalized by Pauling's equation for polar covalent bonds. This opens the possibility to characterize the electronegativity of individual surface atoms. Moreover, we demonstrate that the method is sensitive to variation of the electronegativity of given atomic species on a surface due to different chemical environments. Our findings open up ways of analysing surface chemical reactivity at the atomic scale.

Electronegativity determination of individual surface atoms by atomic force microscopy

PubMed Central

Onoda, Jo; Ondráček, Martin; Jelínek, Pavel; Sugimoto, Yoshiaki

2017-01-01

Electronegativity is a fundamental concept in chemistry. Despite its importance, the experimental determination has been limited only to ensemble-averaged techniques. Here, we report a methodology to evaluate the electronegativity of individual surface atoms by atomic force microscopy. By measuring bond energies on the surface atoms using different tips, we find characteristic linear relations between the bond energies of different chemical species. We show that the linear relation can be rationalized by Pauling's equation for polar covalent bonds. This opens the possibility to characterize the electronegativity of individual surface atoms. Moreover, we demonstrate that the method is sensitive to variation of the electronegativity of given atomic species on a surface due to different chemical environments. Our findings open up ways of analysing surface chemical reactivity at the atomic scale. PMID:28443645

Adaptive deformable model for colonic polyp segmentation and measurement on CT colonography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yao Jianhua; Summers, Ronald M.

2007-05-15

Polyp size is one important biomarker for the malignancy risk of a polyp. This paper presents an improved approach for colonic polyp segmentation and measurement on CT colonography images. The method is based on a combination of knowledge-guided intensity adjustment, fuzzy clustering, and adaptive deformable model. Since polyps on haustral folds are the most difficult to be segmented, we propose a dual-distance algorithm to first identify voxels on the folds, and then introduce a counter-force to control the model evolution. We derive linear and volumetric measurements from the segmentation. The experiment was conducted on 395 patients with 83 polyps, ofmore » which 43 polyps were on haustral folds. The results were validated against manual measurement from the optical colonoscopy and the CT colonography. The paired t-test showed no significant difference, and the R{sup 2} correlation was 0.61 for the linear measurement and 0.98 for the volumetric measurement. The mean Dice coefficient for volume overlap between automatic and manual segmentation was 0.752 (standard deviation 0.154)« less

A Q-Ising model application for linear-time image segmentation

NASA Astrophysics Data System (ADS)

Bentrem, Frank W.

2010-10-01

A computational method is presented which efficiently segments digital grayscale images by directly applying the Q-state Ising (or Potts) model. Since the Potts model was first proposed in 1952, physicists have studied lattice models to gain deep insights into magnetism and other disordered systems. For some time, researchers have realized that digital images may be modeled in much the same way as these physical systems ( i.e., as a square lattice of numerical values). A major drawback in using Potts model methods for image segmentation is that, with conventional methods, it processes in exponential time. Advances have been made via certain approximations to reduce the segmentation process to power-law time. However, in many applications (such as for sonar imagery), real-time processing requires much greater efficiency. This article contains a description of an energy minimization technique that applies four Potts (Q-Ising) models directly to the image and processes in linear time. The result is analogous to partitioning the system into regions of four classes of magnetism. This direct Potts segmentation technique is demonstrated on photographic, medical, and acoustic images.

Energy-efficient rings mechanism for greening multisegment fiber-wireless access networks

NASA Astrophysics Data System (ADS)

Gong, Xiaoxue; Guo, Lei; Hou, Weigang; Zhang, Lincong

2013-07-01

Through integrating advantages of optical and wireless communications, the Fiber-Wireless (FiWi) has become a promising solution for the "last-mile" broadband access. In particular, greening FiWi has attained extensive attention, because the access network is a main energy contributor in the whole infrastructure. However, prior solutions of greening FiWi shut down or sleep unused/minimally used optical network units for a single segment, where we deploy only one optical linear terminal. We propose a green mechanism referred to as energy-efficient ring (EER) for multisegment FiWi access networks. We utilize an integer linear programming model and a generic algorithm to generate clusters, each having the shortest distance of fully connected segments of its own. Leveraging the backtracking method for each cluster, we then connect segments through fiber links, and the shortest distance fiber ring is constructed. Finally, we sleep low load segments and forward affected traffic to other active segments on the same fiber ring by our sleeping scheme. Experimental results show that our EER mechanism significantly reduces the energy consumption at the slightly additional cost of deploying fiber links.

Progress in understanding heavy-ion stopping

NASA Astrophysics Data System (ADS)

Sigmund, P.; Schinner, A.

2016-09-01

We report some highlights of our work with heavy-ion stopping in the energy range where Bethe stopping theory breaks down. Main tools are our binary stopping theory (PASS code), the reciprocity principle, and Paul's data base. Comparisons are made between PASS and three alternative theoretical schemes (CasP, HISTOP and SLPA). In addition to equilibrium stopping we discuss frozen-charge stopping, deviations from linear velocity dependence below the Bragg peak, application of the reciprocity principle in low-velocity stopping, modeling of equilibrium charges, and the significance of the so-called effective charge.

Flexible pipe crawling device having articulated two axis coupling

DOEpatents

Zollinger, William T.

1994-01-01

An apparatus for moving through the linear and non-linear segments of piping systems. The apparatus comprises a front leg assembly, a rear leg assembly, a mechanism for extension and retraction of the front and rear leg assembles with respect to each other, such as an air cylinder, and a pivoting joint. One end of the flexible joint attaches to the front leg assembly and the other end to the air cylinder, which is also connected to the rear leg assembly. The air cylinder allows the front and rear leg assemblies to progress through a pipe in "inchworm" fashion, while the joint provides the flexibility necessary for the pipe crawler to negotiate non-linear piping segments. The flexible connecting joint is coupled with a spring-force suspension system that urges alignment of the front and rear leg assemblies with respect to each other. The joint and suspension system cooperate to provide a firm yet flexible connection between the front and rear leg assemblies to allow the pivoting of one with respect to the other while moving around a non-linear pipe segment, but restoring proper alignment coming out of the pipe bend.

Flexible pipe crawling device having articulated two axis coupling

DOEpatents

Zollinger, W.T.

1994-05-10

An apparatus is described for moving through the linear and non-linear segments of piping systems. The apparatus comprises a front leg assembly, a rear leg assembly, a mechanism for extension and retraction of the front and rear leg assembles with respect to each other, such as an air cylinder, and a pivoting joint. One end of the flexible joint attaches to the front leg assembly and the other end to the air cylinder, which is also connected to the rear leg assembly. The air cylinder allows the front and rear leg assemblies to progress through a pipe in inchworm' fashion, while the joint provides the flexibility necessary for the pipe crawler to negotiate non-linear piping segments. The flexible connecting joint is coupled with a spring-force suspension system that urges alignment of the front and rear leg assemblies with respect to each other. The joint and suspension system cooperate to provide a firm yet flexible connection between the front and rear leg assemblies to allow the pivoting of one with respect to the other while moving around a non-linear pipe segment, but restoring proper alignment coming out of the pipe bend. 4 figures.

76 FR 43958 - Safety Zone; Rotary Club of Fort Lauderdale New River Raft Race, New River, Fort Lauderdale, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... have questions on this proposed rule, call or e-mail Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A.Steiner@uscg.mil . If you have... Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A...

Maniac Talk - Paul Newman

NASA Image and Video Library

2015-02-25

Paul Newman Maniac Lecture, February 25, 2015 NASA climate scientist Dr. Paul Newman presented a Maniac Talk entitled "Some pretty good rules for a career: Newman's own lessons." Paul traced his journey from middle of Seattle, where he grew up, moved to rural Iowa for graduate school, and made his way to NASA/GSFC in 1984, and discussed lessons to be learned from the ozone depletion story.

Segmented media and medium damping in microwave assisted magnetic recording

NASA Astrophysics Data System (ADS)

Bai, Xiaoyu; Zhu, Jian-Gang

2018-05-01

In this paper, we present a methodology of segmented media stack design for microwave assisted magnetic recording. Through micro-magnetic modeling, it is demonstrated that an optimized media segmentation is able to yield high signal-to-noise ratio even with limited ac field power. With proper segmentation, the ac field power could be utilized more efficiently and this can alleviate the requirement for medium damping which has been previously considered a critical limitation. The micro-magnetic modeling also shows that with segmentation optimization, recording signal-to-noise ratio can have very little dependence on damping for different recording linear densities.

Paul Frampton

NASA Astrophysics Data System (ADS)

Williams, Heather A.

2013-01-01

I was astonished by an article that appeared on physicsworld.com in November about the physicist Paul Frampton and his imprisonment for attempted cocaine smuggling ("Paul Frampton hit by 56-month drugs sentence", 22 November 2012).

Linus Pauling and sickle cell disease.

PubMed

Eaton, William A

2003-01-01

The 1949 paper by Linus Pauling et al. [Science 110 (1949) 543-548] describing the discovery of sickle cell anemia as the first molecular disease had a major impact on biology and medicine. Inspired by the scholarly works of John Edsall on the history of hemoglobin research, I present a brief retrospective analysis of Pauling's paper. This is followed by some personal recollections of Edsall and Pauling.

James Webb Space Telescope optical simulation testbed IV: linear control alignment of the primary segmented mirror

NASA Astrophysics Data System (ADS)

Egron, Sylvain; Soummer, Rémi; Lajoie, Charles-Philippe; Bonnefois, Aurélie; Long, Joseph; Michau, Vincent; Choquet, Elodie; Ferrari, Marc; Leboulleux, Lucie; Levecq, Olivier; Mazoyer, Johan; N'Diaye, Mamadou; Perrin, Marshall; Petrone, Peter; Pueyo, Laurent; Sivaramakrishnan, Anand

2017-09-01

The James Webb Space Telescope (JWST) Optical Simulation Testbed (JOST) is a tabletop experiment designed to study wavefront sensing and control for a segmented space telescope, such as JWST. With the JWST Science and Operations Center co-located at STScI, JOST was developed to provide both a platform for staff training and to test alternate wavefront sensing and control strategies for independent validation or future improvements beyond the baseline operations. The design of JOST reproduces the physics of JWST's three-mirror anastigmat (TMA) using three custom aspheric lenses. It provides similar quality image as JWST (80% Strehl ratio) over a field equivalent to a NIRCam module, but at 633 nm. An Iris AO segmented mirror stands for the segmented primary mirror of JWST. Actuators allow us to control (1) the 18 segments of the segmented mirror in piston, tip, tilt and (2) the second lens, which stands for the secondary mirror, in tip, tilt and x, y, z positions. We present the most recent experimental results for the segmented mirror alignment. Our implementation of the Wavefront Sensing (WFS) algorithms using phase diversity is tested on simulation and experimentally. The wavefront control (WFC) algorithms, which rely on a linear model for optical aberrations induced by misalignment of the secondary lens and the segmented mirror, are tested and validated both on simulations and experimentally. In this proceeding, we present the performance of the full active optic control loop in presence of perturbations on the segmented mirror, and we detail the quality of the alignment correction.

Dynamic Changes in the Myometrium during the Third Stage of Labor, Evaluated Using Two-Dimensional Ultrasound, in Women with Normal and Abnormal Third Stage of Labor and in Women with Obstetric Complications.

PubMed

Patwardhan, Manasi; Hernandez-Andrade, Edgar; Ahn, Hyunyoung; Korzeniewski, Steven J; Schwartz, Alyse; Hassan, Sonia S; Romero, Roberto

2015-01-01

To investigate dynamic changes in myometrial thickness during the third stage of labor. Myometrial thickness was measured using ultrasound at one-minute time intervals during the third stage of labor in the mid-region of the upper and lower uterine segments in 151 patients including: women with a long third stage of labor (n = 30), postpartum hemorrhage (n = 4), preterm delivery (n = 7) and clinical chorioamnionitis (n = 4). Differences between myometrial thickness of the uterine segments and as a function of time were evaluated. There was a significant linear increase in the mean myometrial thickness of the upper uterine segments, as well as a significant linear decrease in the mean myometrial thickness of the lower uterine segments until the expulsion of the placenta (p < 0.001). The ratio of the measurements of the upper to the lower uterine segments increased significantly as a function of time (p < 0.0001). In women with postpartum hemorrhage, preterm delivery, and clinical chorioamnionitis, an uncoordinated pattern among the uterine segments was observed. A well-coordinated activity between the upper and lower uterine segments is demonstrated in normal placental delivery. In some clinical conditions this pattern is not observed, increasing the time for placental delivery and the risk of postpartum hemorrhage. © 2015 S. Karger AG, Basel.

Dynamic changes in the myometrium during the third stage of labor, evaluated using two-dimensional ultrasound, in women with normal and abnormal third stage of labor and in women with obstetric complications

PubMed Central

Patwardhan, Manasi; Hernandez-Andrade, Edgar; Ahn, Hyunyoung; Korzeniewski, Steven J; Schwartz, Alyse; Hassan, Sonia S; Romero, Roberto

2015-01-01

Objective To investigate dynamic changes in myometrial thickness during the third stage of labor. Methods Myometrial thickness was measured using ultrasound at one-minute time intervals during the third stage of labor in the mid-region of the upper and lower uterine segments in 151 patients including: women with a long third stage of labor (n=30), post-partum hemorrhage (n=4), preterm delivery (n=7) or clinical chorioamnionitis (n=4). Differences between uterine segments and as a function of time were evaluated. Results There was a significant linear increase in the mean myometrial thickness of the upper uterine segments, as well as a significant linear decrease in the mean myometrial thickness of the lower uterine segments until the expulsion of the placenta (p<0.001). The ratio of the measurements of the upper to the lower uterine segments increased significantly as a function of time (p<0.0001). In women with postpartum hemorrhage, preterm delivery and clinical chorioamnionitis, an uncoordinated pattern between the uterine segments was observed. Conclusion A well-coordinated activity between the upper and lower uterine segments is demonstrated in normal placental delivery. In some clinical conditions this pattern is not observed, increasing the time for placental delivery and the risk for post-partum hemorrhage. PMID:25634647

Precision Linear Actuators for the Spherical Primary Optical Telescope Demonstration Mirror

NASA Technical Reports Server (NTRS)

Budinoff, Jason; Pfenning, David

2006-01-01

The Spherical Primary Optical Telescope (SPOT) is an ongoing research effort at Goddard Space Flight Center developing wavefront sensing and control architectures for future space telescopes. The 03.5-m SPOT telescope primary mirror is comprise9 of six 0.86-m hexagonal mirror segments arranged in a single ring, with the central segment missing. The mirror segments are designed for laboratory use and are not lightweighted to reduce cost. Each primary mirror segment is actuated and has tip, tilt, and piston rigid-body motions. Additionally, the radius of curvature of each mirror segment may be varied mechanically. To provide these degrees of freedom, the SPOT mirror segment assembly requires linear actuators capable of

Controlling retention, selectivity and magnitude of EOF by segmented monolithic columns consisting of octadecyl and naphthyl monolithic segments--applications to RP-CEC of both neutral and charged solutes.

PubMed

Karenga, Samuel; El Rassi, Ziad

2011-04-01

Monolithic capillaries made of two adjoining segments each filled with a different monolith were introduced for the control and manipulation of the electroosmotic flow (EOF), retention and selectivity in reversed phase-capillary electrochromatography (RP-CEC). These columns were called segmented monolithic columns (SMCs) where one segment was filled with a naphthyl methacrylate monolith (NMM) to provide hydrophobic and π-interactions, while the other segment was filled with an octadecyl acrylate monolith (ODM) to provide solely hydrophobic interaction. The ODM segment not only provided hydrophobic interactions but also functioned as the EOF accelerator segment. The average EOF of the SMC increased linearly with increasing the fractional length of the ODM segment. The neutral SMC provided a convenient way for tuning EOF, selectivity and retention in the absence of annoying electrostatic interactions and irreversible solute adsorption. The SMCs allowed the separation of a wide range of neutral solutes including polycyclic aromatic hydrocarbons (PAHs) that are difficult to separate using conventional alkyl-bonded stationary phases. In all cases, the k' of a given solute was a linear function of the fractional length of the ODM or NMM segment in the SMCs, thus facilitating the tailoring of a given SMC to solve a given separation problem. At some ODM fractional length, the fabricated SMC allowed the separation of charged solutes such as peptides and proteins that could not otherwise be achieved on a monolithic column made from NMM as an isotropic stationary phase due to the lower EOF exhibited by this monolith. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Scalable Creation of Long-Lived Multipartite Entanglement

NASA Astrophysics Data System (ADS)

Kaufmann, H.; Ruster, T.; Schmiegelow, C. T.; Luda, M. A.; Kaushal, V.; Schulz, J.; von Lindenfels, D.; Schmidt-Kaler, F.; Poschinger, U. G.

2017-10-01

We demonstrate the deterministic generation of multipartite entanglement based on scalable methods. Four qubits are encoded in 40Ca+, stored in a microstructured segmented Paul trap. These qubits are sequentially entangled by laser-driven pairwise gate operations. Between these, the qubit register is dynamically reconfigured via ion shuttling operations, where ion crystals are separated and merged, and ions are moved in and out of a fixed laser interaction zone. A sequence consisting of three pairwise entangling gates yields a four-ion Greenberger-Horne-Zeilinger state |ψ ⟩=(1 /√{2 })(|0000 ⟩+|1111 ⟩) , and full quantum state tomography reveals a state fidelity of 94.4(3)%. We analyze the decoherence of this state and employ dynamic decoupling on the spatially distributed constituents to maintain 69(5)% coherence at a storage time of 1.1 sec.

Longitudinal Study of the Market Penetration of Cockpit Weather Information Systems

NASA Technical Reports Server (NTRS)

Stough, Harry Paul, III; Sireli, Yesim; Ozan, Erol; Kauffmann, Paul

2005-01-01

The purpose of the longitudinal research of the market penetration of cockpit weather information systems (CWIS) is to contribute to the body of knowledge on modeling advanced technology feasibility in aviation by tracking and analyzing the market adoption of CWIS over a three year period. This research takes advantage of a previous study, conducted by Dr. Paul Kauffmann in 2000, which demonstrated an integrated and cost effective approach to evaluate advanced technology feasibility, examining the feasibility of CWIS in five market segments: transport, commuter, general aviation, business, and rotorcraft. The longitudinal research consists of two consecutive studies and produced two reports. The first report was submitted in August 2003 and included general market analysis about the CWIS products in the market at the time, identified their characteristics and examined developing market dynamics.

Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography.

PubMed

Yong, Yan Ling; Tan, Li Kuo; McLaughlin, Robert A; Chee, Kok Han; Liew, Yih Miin

2017-12-01

Intravascular optical coherence tomography (OCT) is an optical imaging modality commonly used in the assessment of coronary artery diseases during percutaneous coronary intervention. Manual segmentation to assess luminal stenosis from OCT pullback scans is challenging and time consuming. We propose a linear-regression convolutional neural network to automatically perform vessel lumen segmentation, parameterized in terms of radial distances from the catheter centroid in polar space. Benchmarked against gold-standard manual segmentation, our proposed algorithm achieves average locational accuracy of the vessel wall of 22 microns, and 0.985 and 0.970 in Dice coefficient and Jaccard similarity index, respectively. The average absolute error of luminal area estimation is 1.38%. The processing rate is 40.6 ms per image, suggesting the potential to be incorporated into a clinical workflow and to provide quantitative assessment of vessel lumen in an intraoperative time frame. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

Minneapolis-Saint Paul air cargo study

DOT National Transportation Integrated Search

2001-12-01

The Minneapolis-Saint Paul Task Force commissioned this study. It was established to address the apparent decline in air cargo through Minneapolis-Saint Paul airport in recent years. Distribution services, especially international air cargo, are stra...

Trunk motion and gait characteristics of pregnant women when walking: report of a longitudinal study with a control group

PubMed Central

2013-01-01

Background A longitudinal repeated measures design over pregnancy and post-birth, with a control group would provide insight into the mechanical adaptations of the body under conditions of changing load during a common female human lifespan condition, while minimizing the influences of inter human differences. The objective was to investigate systematic changes in the range of motion for the pelvic and thoracic segments of the spine, the motion between these segments (thoracolumbar spine) and temporospatial characteristics of step width, stride length and velocity during walking as pregnancy progresses and post-birth. Methods Nine pregnant women were investigated when walking along a walkway at a self-selected velocity using an 8 camera motion analysis system on four occasions throughout pregnancy and once post birth. A control group of twelve non-pregnant nulliparous women were tested on three occasions over the same time period. The existence of linear trends for change was investigated. Results As pregnancy progresses there was a significant linear trend for increase in step width (p = 0.05) and a significant linear trend for decrease in stride length (p = 0.05). Concurrently there was a significant linear trend for decrease in the range of motion of the pelvic segment (p = 0.03) and thoracolumbar spine (p = 0.01) about a vertical axis (side to side rotation), and the pelvic segment (p = 0.04) range of motion around an anterio-posterior axis (side tilt). Post-birth, step width readapted whereas pelvic (p = 0.02) and thoracic (p < 0.001) segment flexion-extension range of motion decreased and increased respectively. The magnitude of all changes was greater than that accounted for with natural variability with re testing. Conclusions As pregnancy progressed and post-birth there were significant linear trends seen in biomechanical changes when walking at a self-determined natural speed that were greater than that accounted for by natural variability with repeated testing. Not all adaptations were resolved by eight weeks post birth. PMID:23514204

58. Photographic copy of original construction plan (St. Paul Engineer's ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

58. Photographic copy of original construction plan (St. Paul Engineer's Office, Wabasha St. Bridge, Plan of Masonry, February 1899); south abutment - Wabasha Street Bridge, Spanning Mississippi River at Wabasha Street, Saint Paul, Ramsey County, MN

76 FR 73666 - Notice of Inventory Completion: Paul H. Karshner Memorial Museum, Puyallup, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

..., 2011. ADDRESSES: Brian Fox, Director of Instructional Leadership, Puyallup School District, Paul H... criteria in 43 CFR 10.11(c)(1) should contact Brian Fox, Director of Instructional Leadership, Paul H...

The Modern Catholic Just War Tradition

DTIC Science & Technology

2012-04-15

offered a positive solution to the problems facing humanity. In fact in an address to the Vatican Diplomatic Corps, January 13, 2003, Pope John Paul II...cii Pope John Paul II. “Address of His Holiness Pope John Paul II to the Diplomatice Corps.” Speech to the Vatican Diplomatic Corps Libreria...the Vatican Diplomatic Corps Libreria Editrice Vaticana, January 2003. 4 http://www.vatican.va/holy_father/john_paul_ii/speeches/2003/january

Les instabilités antérieures de l’épaule:à propos de 73 cas

PubMed Central

Jamal, Louaste; Bousbaa, Hicham; Cherrad, Taoufik; Wahidi, Mohammed; Amhajji, Larbi; Rachid, Khalid

2016-01-01

Entre 2005 et 2014, 73patients (77 épaules) ont bénéficié d’une intervention de Latarjet pour instabilité antérieure de l’épaule. Nous avons, rétrospectivement, évalué les résultats cliniques et radiologiques de cette technique opératoire. L’intervention a été réalisée pour le traitement d’une luxation récidivante dans 69 cas, subluxation récidivante douloureuse dans 5 cas et 3 épaules douloureuses Tous les patients ont eu une évaluation radiographique avant l’intervention et lors du contrôle le plus récent. Selon le score de Rowe, 73 (94.8 %) des 77 épaules ont obtenu un résultat bon ou excellent. Au plus grand recul, 74 épaules étaient indemnes d’arthrose glénohumérale. PMID:27800066

Treatment of nasal fractures by Paul of Aegina.

PubMed

Skoulakis, Charalampos E; Manios, Andreas G; Theos, Evangelos A; Papadakis, Chariton E; Stavroulaki, Pelagia S

2008-03-01

The most exact description of the management of nasal fractures given by any physician of ancient times belongs to Paul of Aegina (AD 625-690). The goal of this article is to describe the therapeutic methods and surgical techniques used by Paul of Aegina in the treatment of nasal injuries. We studied the original Greek texts and the translation published in Venice, titled "The seven books of excellent doctor Paul of Aegina." The sixth book of his medical compendium is devoted to surgery. We identified the treatments and techniques applied to the restoration of injured noses. In this historical article we present the management of nasal fractures by Paul of Aegina. Paul of Aegina's conservative and surgical management for each form of injury was adopted by later physicians and influenced European medicine, a management surprisingly identical with the way nasal fractures are managed nowadays.

Paul Weiss and the genesis of canonical quantization

NASA Astrophysics Data System (ADS)

Rickles, Dean; Blum, Alexander

2015-12-01

This paper describes the life and work of a figure who, we argue, was of primary importance during the early years of field quantisation and (albeit more indirectly) quantum gravity. A student of Dirac and Born, he was interned in Canada during the second world war as an enemy alien and after his release never seemed to regain a good foothold in physics, identifying thereafter as a mathematician. He developed a general method of quantizing (linear and non-linear) field theories based on the parameters labelling an arbitrary hypersurface. This method (the `parameter formalism' often attributed to Dirac), though later discarded, was employed (and viewed at the time as an extremely important tool) by the leading figures associated with canonical quantum gravity: Dirac, Pirani and Schild, Bergmann, DeWitt, and others. We argue that he deserves wider recognition for this and other innovations.

Unsupervised MRI segmentation of brain tissues using a local linear model and level set.

PubMed

Rivest-Hénault, David; Cheriet, Mohamed

2011-02-01

Real-world magnetic resonance imaging of the brain is affected by intensity nonuniformity (INU) phenomena which makes it difficult to fully automate the segmentation process. This difficult task is accomplished in this work by using a new method with two original features: (1) each brain tissue class is locally modeled using a local linear region representative, which allows us to account for the INU in an implicit way and to more accurately position the region's boundaries; and (2) the region models are embedded in the level set framework, so that the spatial coherence of the segmentation can be controlled in a natural way. Our new method has been tested on the ground-truthed Internet Brain Segmentation Repository (IBSR) database and gave promising results, with Tanimoto indexes ranging from 0.61 to 0.79 for the classification of the white matter and from 0.72 to 0.84 for the gray matter. To our knowledge, this is the first time a region-based level set model has been used to perform the segmentation of real-world MRI brain scans with convincing results. Copyright © 2011 Elsevier Inc. All rights reserved.

Effects of modeling errors on trajectory predictions in air traffic control automation

NASA Technical Reports Server (NTRS)

Jackson, Michael R. C.; Zhao, Yiyuan; Slattery, Rhonda

1996-01-01

Air traffic control automation synthesizes aircraft trajectories for the generation of advisories. Trajectory computation employs models of aircraft performances and weather conditions. In contrast, actual trajectories are flown in real aircraft under actual conditions. Since synthetic trajectories are used in landing scheduling and conflict probing, it is very important to understand the differences between computed trajectories and actual trajectories. This paper examines the effects of aircraft modeling errors on the accuracy of trajectory predictions in air traffic control automation. Three-dimensional point-mass aircraft equations of motion are assumed to be able to generate actual aircraft flight paths. Modeling errors are described as uncertain parameters or uncertain input functions. Pilot or autopilot feedback actions are expressed as equality constraints to satisfy control objectives. A typical trajectory is defined by a series of flight segments with different control objectives for each flight segment and conditions that define segment transitions. A constrained linearization approach is used to analyze trajectory differences caused by various modeling errors by developing a linear time varying system that describes the trajectory errors, with expressions to transfer the trajectory errors across moving segment transitions. A numerical example is presented for a complete commercial aircraft descent trajectory consisting of several flight segments.

Automatic optimal filament segmentation with sub-pixel accuracy using generalized linear models and B-spline level-sets

PubMed Central

Xiao, Xun; Geyer, Veikko F.; Bowne-Anderson, Hugo; Howard, Jonathon; Sbalzarini, Ivo F.

2016-01-01

Biological filaments, such as actin filaments, microtubules, and cilia, are often imaged using different light-microscopy techniques. Reconstructing the filament curve from the acquired images constitutes the filament segmentation problem. Since filaments have lower dimensionality than the image itself, there is an inherent trade-off between tracing the filament with sub-pixel accuracy and avoiding noise artifacts. Here, we present a globally optimal filament segmentation method based on B-spline vector level-sets and a generalized linear model for the pixel intensity statistics. We show that the resulting optimization problem is convex and can hence be solved with global optimality. We introduce a simple and efficient algorithm to compute such optimal filament segmentations, and provide an open-source implementation as an ImageJ/Fiji plugin. We further derive an information-theoretic lower bound on the filament segmentation error, quantifying how well an algorithm could possibly do given the information in the image. We show that our algorithm asymptotically reaches this bound in the spline coefficients. We validate our method in comprehensive benchmarks, compare with other methods, and show applications from fluorescence, phase-contrast, and dark-field microscopy. PMID:27104582

11. Photocopy of photograph (from St. Paul's Church) Photographer unknown ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopy of photograph (from St. Paul's Church) Photographer unknown 1886 'EPISCOPAL CHURCH, CORNER OF 1ST AND J ST. BENICIA' WEST AND SOUTH SIDES - St. Paul's Episcopal Church, 120 East J Street, Benicia, Solano County, CA

Figure-ground segmentation based on class-independent shape priors

NASA Astrophysics Data System (ADS)

Li, Yang; Liu, Yang; Liu, Guojun; Guo, Maozu

2018-01-01

We propose a method to generate figure-ground segmentation by incorporating shape priors into the graph-cuts algorithm. Given an image, we first obtain a linear representation of an image and then apply directional chamfer matching to generate class-independent, nonparametric shape priors, which provide shape clues for the graph-cuts algorithm. We then enforce shape priors in a graph-cuts energy function to produce object segmentation. In contrast to previous segmentation methods, the proposed method shares shape knowledge for different semantic classes and does not require class-specific model training. Therefore, the approach obtains high-quality segmentation for objects. We experimentally validate that the proposed method outperforms previous approaches using the challenging PASCAL VOC 2010/2012 and Berkeley (BSD300) segmentation datasets.

Global Ocean Sedimentation Patterns: Plate Tectonic History Versus Climate Change

NASA Astrophysics Data System (ADS)

Goswami, A.; Reynolds, E.; Olson, P.; Hinnov, L. A.; Gnanadesikan, A.

2014-12-01

Global sediment data (Whittaker et al., 2013) and carbonate content data (Archer, 1996) allows examination of ocean sedimentation evolution with respect to age of the underlying ocean crust (Müller et al., 2008). From these data, we construct time series of ocean sediment thickness and carbonate deposition rate for the Atlantic, Pacific, and Indian ocean basins for the past 120 Ma. These time series are unique to each basin and reflect an integrated response to plate tectonics and climate change. The goal is to parameterize ocean sedimentation tied to crustal age for paleoclimate studies. For each basin, total sediment thickness and carbonate deposition rate from 0.1 x 0.1 degree cells are binned according to basement crustal age; area-corrected moments (mean, variance, etc.) are calculated for each bin. Segmented linear fits identify trends in present-day carbonate deposition rates and changes in ocean sedimentation from 0 to 120 Ma. In the North and South Atlantic and Indian oceans, mean sediment thickness versus crustal age is well represented by three linear segments, with the slope of each segment increasing with increasing crustal age. However, the transition age between linear segments varies among the three basins. In contrast, mean sediment thickness in the North and South Pacific oceans are numerically smaller and well represented by two linear segments with slopes that decrease with increasing crustal age. These opposing trends are more consistent with the plate tectonic history of each basin being the controlling factor in sedimentation rates, rather than climate change. Unlike total sediment thickness, carbonate deposition rates decrease smoothly with crustal age in all basins, with the primary controls being ocean chemistry and water column depth.References: Archer, D., 1996, Global Biogeochem. Cycles 10, 159-174.Müller, R.D., et al., 2008, Science, 319, 1357-1362.Whittaker, J., et al., 2013, Geochem., Geophys., Geosyst. DOI: 10.1002/ggge.20181

Method and Excel VBA Algorithm for Modeling Master Recession Curve Using Trigonometry Approach.

PubMed

Posavec, Kristijan; Giacopetti, Marco; Materazzi, Marco; Birk, Steffen

2017-11-01

A new method was developed and implemented into an Excel Visual Basic for Applications (VBAs) algorithm utilizing trigonometry laws in an innovative way to overlap recession segments of time series and create master recession curves (MRCs). Based on a trigonometry approach, the algorithm horizontally translates succeeding recession segments of time series, placing their vertex, that is, the highest recorded value of each recession segment, directly onto the appropriate connection line defined by measurement points of a preceding recession segment. The new method and algorithm continues the development of methods and algorithms for the generation of MRC, where the first published method was based on a multiple linear/nonlinear regression model approach (Posavec et al. 2006). The newly developed trigonometry-based method was tested on real case study examples and compared with the previously published multiple linear/nonlinear regression model-based method. The results show that in some cases, that is, for some time series, the trigonometry-based method creates narrower overlaps of the recession segments, resulting in higher coefficients of determination R 2 , while in other cases the multiple linear/nonlinear regression model-based method remains superior. The Excel VBA algorithm for modeling MRC using the trigonometry approach is implemented into a spreadsheet tool (MRCTools v3.0 written by and available from Kristijan Posavec, Zagreb, Croatia) containing the previously published VBA algorithms for MRC generation and separation. All algorithms within the MRCTools v3.0 are open access and available free of charge, supporting the idea of running science on available, open, and free of charge software. © 2017, National Ground Water Association.

Cortical bone fracture analysis using XFEM - case study.

PubMed

Idkaidek, Ashraf; Jasiuk, Iwona

2017-04-01

We aim to achieve an accurate simulation of human cortical bone fracture using the extended finite element method within a commercial finite element software abaqus. A two-dimensional unit cell model of cortical bone is built based on a microscopy image of the mid-diaphysis of tibia of a 70-year-old human male donor. Each phase of this model, an interstitial bone, a cement line, and an osteon, are considered linear elastic and isotropic with material properties obtained by nanoindentation, taken from literature. The effect of using fracture analysis methods (cohesive segment approach versus linear elastic fracture mechanics approach), finite element type, and boundary conditions (traction, displacement, and mixed) on cortical bone crack initiation and propagation are studied. In this study cohesive segment damage evolution for a traction separation law based on energy and displacement is used. In addition, effects of the increment size and mesh density on analysis results are investigated. We find that both cohesive segment and linear elastic fracture mechanics approaches within the extended finite element method can effectively simulate cortical bone fracture. Mesh density and simulation increment size can influence analysis results when employing either approach, and using finer mesh and/or smaller increment size does not always provide more accurate results. Both approaches provide close but not identical results, and crack propagation speed is found to be slower when using the cohesive segment approach. Also, using reduced integration elements along with the cohesive segment approach decreases crack propagation speed compared with using full integration elements. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Segmented Polynomial Models in Quasi-Experimental Research.

ERIC Educational Resources Information Center

Wasik, John L.

1981-01-01

The use of segmented polynomial models is explained. Examples of design matrices of dummy variables are given for the least squares analyses of time series and discontinuity quasi-experimental research designs. Linear combinations of dummy variable vectors appear to provide tests of effects in the two quasi-experimental designs. (Author/BW)

The influence of chemical structure on thermal properties and surface morphology of polyurethane materials.

PubMed

Brzeska, Joanna; Morawska, Magda; Heimowska, Aleksandra; Sikorska, Wanda; Wałach, Wojciech; Hercog, Anna; Kowalczuk, Marek; Rutkowska, Maria

2018-01-01

The surface morphology and thermal properties of polyurethanes can be correlated to their chemical composition. The hydrophilicity, surface morphology, and thermal properties of polyurethanes (differed in soft segments and in linear/cross-linked structure) were investigated. The influence of poly([ R , S ]-3-hydroxybutyrate) presence in soft segments and blending of polyurethane with polylactide on surface topography were also estimated. The linear polyurethanes (partially crystalline) had the granular surface, whereas the surface of cross-linked polyurethanes (almost amorphous) was smooth. Round aggregates of polylactide un-uniformly distributed in matrix of polyurethane were clearly visible. It was concluded that some modification of soft segment (by mixing of poly([ R , S ]-3-hydroxybutyrate) with different polydiols and polytriol) and blending of polyurethanes with small amount of polylactide influence on crystallinity and surface topography of obtained polyurethanes.

Factorization-based texture segmentation

DOE PAGES

Yuan, Jiangye; Wang, Deliang; Cheriyadat, Anil M.

2015-06-17

This study introduces a factorization-based approach that efficiently segments textured images. We use local spectral histograms as features, and construct an M × N feature matrix using M-dimensional feature vectors in an N-pixel image. Based on the observation that each feature can be approximated by a linear combination of several representative features, we factor the feature matrix into two matrices-one consisting of the representative features and the other containing the weights of representative features at each pixel used for linear combination. The factorization method is based on singular value decomposition and nonnegative matrix factorization. The method uses local spectral histogramsmore » to discriminate region appearances in a computationally efficient way and at the same time accurately localizes region boundaries. Finally, the experiments conducted on public segmentation data sets show the promise of this simple yet powerful approach.« less

Palaeointensities from Pliocene lava sequences in Iceland: emphasis on the problem of Arai plot with two linear segments

NASA Astrophysics Data System (ADS)

Tanaka, Hidefumi; Yamamoto, Yuhji

2016-05-01

Palaeointensity experiments were carried out to a sample collection from two sections of basalt lava flow sequences of Pliocene age in north central Iceland (Chron C2An) to further refine the knowledge of the behaviour of the palaeomagnetic field. Selection of samples was mainly based on their stability of remanence to thermal demagnetization as well as good reversibility in variations of magnetic susceptibility and saturation magnetization with temperature, which would indicate the presence of magnetite as a product of deuteric oxidation of titanomagnetite. Among 167 lava flows from two sections, 44 flows were selected for the Königsberger-Thellier-Thellier experiment in vacuum. In spite of careful pre-selection of samples, an Arai plot with two linear segments, or a concave-up appearance, was often encountered during the experiments. This non-ideal behaviour was probably caused by an irreversible change in the domain state of the magnetic grains of the pseudo-single-domain (PSD) range. This is assumed because an ideal linear plot was obtained in the second run of the palaeointensity experiment in which a laboratory thermoremanence acquired after the final step of the first run was used as a natural remanence. This experiment was conducted on six selected samples, and no clear difference between the magnetic grains of the experimented and pristine sister samples was found by scanning electron microscope and hysteresis measurements, that is, no occurrence of notable chemical/mineralogical alteration, suggesting that no change in the grain size distribution had occurred. Hence, the two-segment Arai plot was not caused by the reversible multidomain/PSD effect in which the curvature of the Arai plot is dependent on the grain size. Considering that the irreversible change in domain state must have affected data points at not only high temperatures but also low temperatures, fv ≥ 0.5 was adopted as one of the acceptance criteria where fv is a vectorially defined fraction of the linear segment. A measure of curvature k' was also used to check the linearity of the selected linear segment. It was avoided, however, to reject the result out of hand by the large curvature k of the entire data points because it might still include a linear segment with a large fraction. Combining with the results of Shaw's experiments, 52 palaeointensities were obtained out of 192 specimens, or 11 flow means were obtained out of the 44 lava flows. Most of the palaeointensities were from the upper part of the lava section (Chron C2An.1n) and ranged between 30 and 66 μT. Including two results from the bottom part of the lava section, the mean virtual dipole moment for 2.5-3.5 Ma is 6.3 ± 1.4 × 1022 Am2 (N = 11), which is ˜19 per cent smaller than the present-day dipole moment.

A Perspective on Research Challenges in Information Security

DTIC Science & Technology

2011-11-01

UNCLASSIFIED A Perspective on Research Challenges in Information Security Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos ...Abstract (U) 4. AUTHORS Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos , Ben Long, Mar- tin Lucas, Paul Montague, Dean Philp

Generalized Dicke Nonequilibrium Dynamics in Trapped Ions

NASA Astrophysics Data System (ADS)

Genway, Sam; Li, Weibin; Ates, Cenap; Lanyon, Benjamin P.; Lesanovsky, Igor

2014-01-01

We explore trapped ions as a setting to investigate nonequilibrium phases in a generalized Dicke model of dissipative spins coupled to phonon modes. We find a rich dynamical phase diagram including superradiantlike regimes, dynamical phase coexistence, and phonon-lasing behavior. A particular advantage of trapped ions is that these phases and transitions among them can be probed in situ through fluorescence. We demonstrate that the main physical insights are captured by a minimal model and consider an experimental realization with Ca+ ions trapped in a linear Paul trap with a dressing scheme to create effective two-level systems with a tunable dissipation rate.

Automatic sleep staging using empirical mode decomposition, discrete wavelet transform, time-domain, and nonlinear dynamics features of heart rate variability signals.

PubMed

Ebrahimi, Farideh; Setarehdan, Seyed-Kamaledin; Ayala-Moyeda, Jose; Nazeran, Homer

2013-10-01

The conventional method for sleep staging is to analyze polysomnograms (PSGs) recorded in a sleep lab. The electroencephalogram (EEG) is one of the most important signals in PSGs but recording and analysis of this signal presents a number of technical challenges, especially at home. Instead, electrocardiograms (ECGs) are much easier to record and may offer an attractive alternative for home sleep monitoring. The heart rate variability (HRV) signal proves suitable for automatic sleep staging. Thirty PSGs from the Sleep Heart Health Study (SHHS) database were used. Three feature sets were extracted from 5- and 0.5-min HRV segments: time-domain features, nonlinear-dynamics features and time-frequency features. The latter was achieved by using empirical mode decomposition (EMD) and discrete wavelet transform (DWT) methods. Normalized energies in important frequency bands of HRV signals were computed using time-frequency methods. ANOVA and t-test were used for statistical evaluations. Automatic sleep staging was based on HRV signal features. The ANOVA followed by a post hoc Bonferroni was used for individual feature assessment. Most features were beneficial for sleep staging. A t-test was used to compare the means of extracted features in 5- and 0.5-min HRV segments. The results showed that the extracted features means were statistically similar for a small number of features. A separability measure showed that time-frequency features, especially EMD features, had larger separation than others. There was not a sizable difference in separability of linear features between 5- and 0.5-min HRV segments but separability of nonlinear features, especially EMD features, decreased in 0.5-min HRV segments. HRV signal features were classified by linear discriminant (LD) and quadratic discriminant (QD) methods. Classification results based on features from 5-min segments surpassed those obtained from 0.5-min segments. The best result was obtained from features using 5-min HRV segments classified by the LD classifier. A combination of linear/nonlinear features from HRV signals is effective in automatic sleep staging. Moreover, time-frequency features are more informative than others. In addition, a separability measure and classification results showed that HRV signal features, especially nonlinear features, extracted from 5-min segments are more discriminative than those from 0.5-min segments in automatic sleep staging. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Excitation of transverse dipole and quadrupole modes in a pure ion plasma in a linear Paul trap to study collective processes in intense beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilson, Erik P.; Davidson, Ronald C.; Efthimion, Philip C.

Transverse dipole and quadrupole modes have been excited in a one-component cesium ion plasma trapped in the Paul Trap Simulator Experiment (PTSX) in order to characterize their properties and understand the effect of their excitation on equivalent long-distance beam propagation. The PTSX device is a compact laboratory Paul trap that simulates the transverse dynamics of a long, intense charge bunch propagating through an alternating-gradient transport system by putting the physicist in the beam's frame of reference. A pair of arbitrary function generators was used to apply trapping voltage waveform perturbations with a range of frequencies and, by changing which electrodesmore » were driven with the perturbation, with either a dipole or quadrupole spatial structure. The results presented in this paper explore the dependence of the perturbation voltage's effect on the perturbation duration and amplitude. Perturbations were also applied that simulate the effect of random lattice errors that exist in an accelerator with quadrupole magnets that are misaligned or have variance in their field strength. The experimental results quantify the growth in the equivalent transverse beam emittance that occurs due to the applied noise and demonstrate that the random lattice errors interact with the trapped plasma through the plasma's internal collective modes. Coherent periodic perturbations were applied to simulate the effects of magnet errors in circular machines such as storage rings. The trapped one component plasma is strongly affected when the perturbation frequency is commensurate with a plasma mode frequency. The experimental results, which help to understand the physics of quiescent intense beam propagation over large distances, are compared with analytic models.« less

[Fatal diseases and "imaginary" suffering. "Hypochondria" and "consumption" in the correspondence between Jean Paul and Johann Bernhard Hermann, with a perspective on Jean Paul's literature and aesthetics].

PubMed

Meier, Monika

2007-01-01

The German writerJean Paul (Johann Paul Friedrich Richter, 1763-1825) and his friendJohann Bernhard Hermann (1761-1790) became acquainted with the thoughts of late Enlightenment at the University of Leipzig. They particularly appreciated the anthropology of Ernst Platner, who taught philosophy and aesthetics as well as medicine. Their confidential correspondence contains reflections on their respective situation and well being. Both write about feeling ill and label their illness "hypochondria". In the course of the correspondence Jean Paul's understanding of hypochondria evolves from an illness of the entrails as he follows Hermann, who supports the modern concept of hypochondria as an illness of the nerves. Two important themes from this correspondence recur in Jean Paul's novels and tales: firstly, his way of expressing comfort is related to his aesthetics, and secondly, the satirical way of portraying at least certain aspects of illness as imaginary reappears in his first successful novel "The Invisible Lodge" (1793).

A cross-cultural comparison of eating behaviors and home food environmental factors in adolescents from São Paulo (Brazil) and Saint Paul/Minneapolis (USA)

PubMed Central

Estima, Camilla C.P.; Bruening, Meg; Hannan, Peter J.; Alvarenga, Marle S.; Leal, Greisse V.S.; Philippi, Sonia T.; Neumark-Sztainer, Dianne

2015-01-01

Objective Describe cross-cultural differences in nutrition-related factors among adolescents from São Paulo, Brazil and St. Paul/Minneapolis, U.S. Design Two large- population-based studies with cross-cultural comparisons Setting 12 São Paulo and 10 St. Paul/Minneapolis high schools in 2009-2010 Participants 1148 adolescents from São Paulo; 1632 adolescents from St. Paul/Minneapolis Main outcome measure(s) Meal consumption, family meals, fast food consumption and home food availability Analysis Binomial regressions, weighted for age distributions and adjusted for gender, were used to compare identical measures from each sample. Results Generally, São Paulo adolescents reported healthier nutritional outcomes than St. Paul/Minneapolis adolescents. São Paulo adolescents were seven times less likely to report high fast food consumption than St. Paul/Minneapolis adolescents (p<0.001). While most measures of the home environment indicated healthier home environments in São Paulo, more São Paulo adolescents reported that sugar-sweetened beverages was usually available at home than St. Paul/Minneapolis adolescents (p<0.001). Conclusions and implications São Paulo youth tended to have healthier eating behaviors and home food environment factors than St. Paul/Minneapolis youth. Brazilian eating patterns tend to be healthier and support a connection with food and culture. Interventions are needed to encourage youth and their families to maintain these patterns. PMID:24656651

A cross-cultural comparison of eating behaviors and home food environmental factors in adolescents from São Paulo (Brazil) and Saint Paul-Minneapolis (US).

PubMed

Estima, Camilla C P; Bruening, Meg; Hannan, Peter J; Alvarenga, Marle S; Leal, Greisse V S; Philippi, Sonia T; Neumark-Sztainer, Dianne

2014-01-01

Describe cross-cultural differences in nutrition-related factors among adolescents from São Paulo, Brazil and St Paul-Minneapolis, US. Two large-population-based studies with cross-cultural comparisons. Twelve São Paulo and 10 St Paul-Minneapolis high schools in 2009-2010. A total of 1,148 adolescents from São Paulo and 1,632 adolescents from St Paul-Minneapolis. Meal consumption, family meals, fast-food consumption, and home food availability. Binomial regressions, weighted for age distributions and adjusted for gender, were used to compare identical measures from each sample. Generally, São Paulo adolescents reported healthier nutritional outcomes than St Paul-Minneapolis adolescents. São Paulo adolescents were 7 times less likely to report high fast-food consumption than St Paul-Minneapolis adolescents (P < .001). Whereas most measures of the home environment indicated healthier home environments in São Paulo, more São Paulo adolescents reported that sugar-sweetened beverages were usually available at home than did St Paul-Minneapolis adolescents (P < .001). São Paulo youth tended to have healthier eating behaviors and home food environment factors than St Paul-Minneapolis youth. Brazilian eating patterns tend to be healthier and support a connection with food and culture. Interventions are needed to encourage youth and their families to maintain these patterns. Copyright © 2014 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

Scale effects and morphological diversification in hindlimb segment mass proportions in neognath birds.

PubMed

Kilbourne, Brandon M

2014-01-01

In spite of considerable work on the linear proportions of limbs in amniotes, it remains unknown whether differences in scale effects between proximal and distal limb segments has the potential to influence locomotor costs in amniote lineages and how changes in the mass proportions of limbs have factored into amniote diversification. To broaden our understanding of how the mass proportions of limbs vary within amniote lineages, I collected data on hindlimb segment masses - thigh, shank, pes, tarsometatarsal segment, and digits - from 38 species of neognath birds, one of the most speciose amniote clades. I scaled each of these traits against measures of body size (body mass) and hindlimb size (hindlimb length) to test for departures from isometry. Additionally, I applied two parameters of trait evolution (Pagel's λ and δ) to understand patterns of diversification in hindlimb segment mass in neognaths. All segment masses are positively allometric with body mass. Segment masses are isometric with hindlimb length. When examining scale effects in the neognath subclade Land Birds, segment masses were again positively allometric with body mass; however, shank, pedal, and tarsometatarsal segment masses were also positively allometric with hindlimb length. Methods of branch length scaling to detect phylogenetic signal (i.e., Pagel's λ) and increasing or decreasing rates of trait change over time (i.e., Pagel's δ) suffer from wide confidence intervals, likely due to small sample size and deep divergence times. The scaling of segment masses appears to be more strongly related to the scaling of limb bone mass as opposed to length, and the scaling of hindlimb mass distribution is more a function of scale effects in limb posture than proximo-distal differences in the scaling of limb segment mass. Though negative allometry of segment masses appears to be precluded by the need for mechanically sound limbs, the positive allometry of segment masses relative to body mass may underlie scale effects in stride frequency and length between smaller and larger neognaths. While variation in linear proportions of limbs appear to be governed by developmental mechanisms, variation in mass proportions does not appear to be constrained so.

Scale effects and morphological diversification in hindlimb segment mass proportions in neognath birds

PubMed Central

2014-01-01

Introduction In spite of considerable work on the linear proportions of limbs in amniotes, it remains unknown whether differences in scale effects between proximal and distal limb segments has the potential to influence locomotor costs in amniote lineages and how changes in the mass proportions of limbs have factored into amniote diversification. To broaden our understanding of how the mass proportions of limbs vary within amniote lineages, I collected data on hindlimb segment masses – thigh, shank, pes, tarsometatarsal segment, and digits – from 38 species of neognath birds, one of the most speciose amniote clades. I scaled each of these traits against measures of body size (body mass) and hindlimb size (hindlimb length) to test for departures from isometry. Additionally, I applied two parameters of trait evolution (Pagel’s λ and δ) to understand patterns of diversification in hindlimb segment mass in neognaths. Results All segment masses are positively allometric with body mass. Segment masses are isometric with hindlimb length. When examining scale effects in the neognath subclade Land Birds, segment masses were again positively allometric with body mass; however, shank, pedal, and tarsometatarsal segment masses were also positively allometric with hindlimb length. Methods of branch length scaling to detect phylogenetic signal (i.e., Pagel’s λ) and increasing or decreasing rates of trait change over time (i.e., Pagel’s δ) suffer from wide confidence intervals, likely due to small sample size and deep divergence times. Conclusions The scaling of segment masses appears to be more strongly related to the scaling of limb bone mass as opposed to length, and the scaling of hindlimb mass distribution is more a function of scale effects in limb posture than proximo-distal differences in the scaling of limb segment mass. Though negative allometry of segment masses appears to be precluded by the need for mechanically sound limbs, the positive allometry of segment masses relative to body mass may underlie scale effects in stride frequency and length between smaller and larger neognaths. While variation in linear proportions of limbs appear to be governed by developmental mechanisms, variation in mass proportions does not appear to be constrained so. PMID:24876886

Scalable Creation of Long-Lived Multipartite Entanglement.

PubMed

Kaufmann, H; Ruster, T; Schmiegelow, C T; Luda, M A; Kaushal, V; Schulz, J; von Lindenfels, D; Schmidt-Kaler, F; Poschinger, U G

2017-10-13

We demonstrate the deterministic generation of multipartite entanglement based on scalable methods. Four qubits are encoded in ^{40}Ca^{+}, stored in a microstructured segmented Paul trap. These qubits are sequentially entangled by laser-driven pairwise gate operations. Between these, the qubit register is dynamically reconfigured via ion shuttling operations, where ion crystals are separated and merged, and ions are moved in and out of a fixed laser interaction zone. A sequence consisting of three pairwise entangling gates yields a four-ion Greenberger-Horne-Zeilinger state |ψ⟩=(1/sqrt[2])(|0000⟩+|1111⟩), and full quantum state tomography reveals a state fidelity of 94.4(3)%. We analyze the decoherence of this state and employ dynamic decoupling on the spatially distributed constituents to maintain 69(5)% coherence at a storage time of 1.1 sec.

Automated posterior cranial fossa volumetry by MRI: applications to Chiari malformation type I.

PubMed

Bagci, A M; Lee, S H; Nagornaya, N; Green, B A; Alperin, N

2013-09-01

Quantification of PCF volume and the degree of PCF crowdedness were found beneficial for differential diagnosis of tonsillar herniation and prediction of surgical outcome in CMI. However, lack of automated methods limits the clinical use of PCF volumetry. An atlas-based method for automated PCF segmentation tailored for CMI is presented. The method performance is assessed in terms of accuracy and spatial overlap with manual segmentation. The degree of association between PCF volumes and the lengths of previously proposed linear landmarks is reported. T1-weighted volumetric MR imaging data with 1-mm isotropic resolution obtained with the use of a 3T scanner from 14 patients with CMI and 3 healthy subjects were used for the study. Manually delineated PCF from 9 patients was used to establish a CMI-specific reference for an atlas-based automated PCF parcellation approach. Agreement between manual and automated segmentation of 5 different CMI datasets was verified by means of the t test. Measurement reproducibility was established through the use of 2 repeated scans from 3 healthy subjects. Degree of linear association between PCF volume and 6 linear landmarks was determined by means of Pearson correlation. PCF volumes measured by use of the automated method and with manual delineation were similar, 196.2 ± 8.7 mL versus 196.9 ± 11.0 mL, respectively. The mean relative difference of -0.3 ± 1.9% was not statistically significant. Low measurement variability, with a mean absolute percentage value of 0.6 ± 0.2%, was achieved. None of the PCF linear landmarks were significantly associated with PCF volume. PCF and tissue content volumes can be reliably measured in patients with CMI by use of an atlas-based automated segmentation method.

A new method to approximate load-displacement relationships of spinal motion segments for patient-specific multi-body models of scoliotic spine.

PubMed

Jalalian, Athena; Tay, Francis E H; Arastehfar, Soheil; Liu, Gabriel

2017-06-01

Load-displacement relationships of spinal motion segments are crucial factors in characterizing the stiffness of scoliotic spine models to mimic the spine responses to loads. Although nonlinear approach to approximation of the relationships can be superior to linear ones, little mention has been made to deriving personalized nonlinear load-displacement relationships in previous studies. A method is developed for nonlinear approximation of load-displacement relationships of spinal motion segments to assist characterizing in vivo the stiffness of spine models. We propose approximation by tangent functions and focus on rotational displacements in lateral direction. The tangent functions are characterized using lateral bending test. A multi-body model was characterized to 18 patients and utilized to simulate four spine positions; right bending, left bending, neutral, and traction. The same was done using linear functions to assess the performance of the proposed tangent function in comparison with the linear function. Root-mean-square error (RMSE) of the displacements estimated by the tangent functions was 44 % smaller than the linear functions. This shows the ability of our tangent function in approximation of the relationships for a range of infinitesimal to large displacements involved in the spine movement to the four positions. In addition, the models based on the tangent functions yielded 67, 55, and 39 % smaller RMSEs of Ferguson angles, locations of vertebrae, and orientations of vertebrae, respectively, implying better estimates of spine responses to loads. Overall, it can be concluded that our method for approximating load-displacement relationships of spinal motion segments can offer good estimates of scoliotic spine stiffness.

High-contrast imaging with an arbitrary aperture: active correction of aperture discontinuities

NASA Astrophysics Data System (ADS)

Pueyo, Laurent; Norman, Colin; Soummer, Rémi; Perrin, Marshall; N'Diaye, Mamadou; Choquet, Elodie

2013-09-01

We present a new method to achieve high-contrast images using segmented and/or on-axis telescopes. Our approach relies on using two sequential Deformable Mirrors to compensate for the large amplitude excursions in the telescope aperture due to secondary support structures and/or segment gaps. In this configuration the parameter landscape of Deformable Mirror Surfaces that yield high contrast Point Spread Functions is not linear, and non-linear methods are needed to find the true minimum in the optimization topology. We solve the highly non-linear Monge-Ampere equation that is the fundamental equation describing the physics of phase induced amplitude modulation. We determine the optimum configuration for our two sequential Deformable Mirror system and show that high-throughput and high contrast solutions can be achieved using realistic surface deformations that are accessible using existing technologies. We name this process Active Compensation of Aperture Discontinuities (ACAD). We show that for geometries similar to JWST, ACAD can attain at least 10-7 in contrast and an order of magnitude higher for future Extremely Large Telescopes, even when the pupil features a missing segment" . We show that the converging non-linear mappings resulting from our Deformable Mirror shapes actually damp near-field diffraction artifacts in the vicinity of the discontinuities. Thus ACAD actually lowers the chromatic ringing due to diffraction by segment gaps and strut's while not amplifying the diffraction at the aperture edges beyond the Fresnel regime and illustrate the broadband properties of ACAD in the case of the pupil configuration corresponding to the Astrophysics Focused Telescope Assets. Since details about these telescopes are not yet available to the broader astronomical community, our test case is based on a geometry mimicking the actual one, to the best of our knowledge.

Drawing the line between constituent structure and coherence relations in visual narratives

PubMed Central

Cohn, Neil; Bender, Patrick

2016-01-01

Theories of visual narrative understanding have often focused on the changes in meaning across a sequence, like shifts in characters, spatial location, and causation, as cues for breaks in the structure of a discourse. In contrast, the theory of Visual Narrative Grammar posits that hierarchic “grammatical” structures operate at the discourse level using categorical roles for images, which may or may not co-occur with shifts in coherence. We therefore examined the relationship between narrative structure and coherence shifts in the segmentation of visual narrative sequences using a “segmentation task” where participants drew lines between images in order to divide them into sub-episodes. We used regressions to analyze the influence of the expected constituent structure boundary, narrative categories, and semantic coherence relationships on the segmentation of visual narrative sequences. Narrative categories were a stronger predictor of segmentation than linear coherence relationships between panels, though both influenced participants’ divisions. Altogether, these results support the theory that meaningful sequential images use a narrative grammar that extends above and beyond linear semantic shifts between discourse units. PMID:27709982

Drawing the line between constituent structure and coherence relations in visual narratives.

PubMed

Cohn, Neil; Bender, Patrick

2017-02-01

Theories of visual narrative understanding have often focused on the changes in meaning across a sequence, like shifts in characters, spatial location, and causation, as cues for breaks in the structure of a discourse. In contrast, the theory of visual narrative grammar posits that hierarchic "grammatical" structures operate at the discourse level using categorical roles for images, which may or may not co-occur with shifts in coherence. We therefore examined the relationship between narrative structure and coherence shifts in the segmentation of visual narrative sequences using a "segmentation task" where participants drew lines between images in order to divide them into subepisodes. We used regressions to analyze the influence of the expected constituent structure boundary, narrative categories, and semantic coherence relationships on the segmentation of visual narrative sequences. Narrative categories were a stronger predictor of segmentation than linear coherence relationships between panels, though both influenced participants' divisions. Altogether, these results support the theory that meaningful sequential images use a narrative grammar that extends above and beyond linear semantic shifts between discourse units. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

A fully automatic three-step liver segmentation method on LDA-based probability maps for multiple contrast MR images.

PubMed

Gloger, Oliver; Kühn, Jens; Stanski, Adam; Völzke, Henry; Puls, Ralf

2010-07-01

Automatic 3D liver segmentation in magnetic resonance (MR) data sets has proven to be a very challenging task in the domain of medical image analysis. There exist numerous approaches for automatic 3D liver segmentation on computer tomography data sets that have influenced the segmentation of MR images. In contrast to previous approaches to liver segmentation in MR data sets, we use all available MR channel information of different weightings and formulate liver tissue and position probabilities in a probabilistic framework. We apply multiclass linear discriminant analysis as a fast and efficient dimensionality reduction technique and generate probability maps then used for segmentation. We develop a fully automatic three-step 3D segmentation approach based upon a modified region growing approach and a further threshold technique. Finally, we incorporate characteristic prior knowledge to improve the segmentation results. This novel 3D segmentation approach is modularized and can be applied for normal and fat accumulated liver tissue properties. Copyright 2010 Elsevier Inc. All rights reserved.

[From Paul Flechsig to the Paul Flechsig Institute for Brain Research. Development of brain research at the Karl Marx University].

PubMed

Leibnitz, L; Werner, L; Schober, W; Brauer, K

1977-04-01

A review is given on the development of the brain research institute of the Karl-Marx-University of Leipzig during the directorates of Paul Flechsig (1883-1920), Richard Arwed Pfeifer (1925-1957), and Wolfgang Wünscher (1957-1971).

67. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

67. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul Minnesota, ca. 1925. #35109. Photographer: St. Paul Daily News.) VIEW TO NORTHEAST, SHOWING SPAN NOS. 9-19, ca. 1925 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

63. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

63. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1958. #31008. Photographer: St. Paul Dispatch-Pioneer Press.) AERIAL VIEW OF HIGH BRIDGE, LOOKING SOUTHWEST, 1958 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

68. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

68. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1924. #35108. Photographer: St. Paul Daily News.) VIEW TO EAST, SHOWING SPAN NOS. 10-20, 1924 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

Catalytic Creativity: The Case of Linus Pauling.

ERIC Educational Resources Information Center

Nakamura, Jeanne; Csikszentmihalyi, Mihaly

2001-01-01

Illustrates how creativity is constituted by forces beyond the innovating individual, drawing examples from the career of chemist Linus Pauling that highlight the formative influence of the social field on an individual's relationship to the domain. Pauling's case reveals how variously the social field contributes to creativity, shaping the…

Debating Paul

ERIC Educational Resources Information Center

Torbett, David

2007-01-01

This classroom note describes the lessons I learned from the use of formal debates during the two semesters I taught "Paul and Early Christianity" to undergraduates at a liberal arts college in Ohio. The purpose of the course was primarily to give students the exegetical skills to understand Paul in his own context. The secondary purpose…

78 FR 76143 - Proposed CERCLA Settlement Relating to the Paul's Tank Cleaning Service Superfund Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... Paul's Tank Cleaning Service Superfund Site, Burlington County, New Jersey AGENCY: Environmental.... (``Settling Party''). The Settling Party is a potentially responsible party, pursuant to Section 107(a) of CERCLA, and thus is potentially liable for response costs incurred at or in connection Paul's Tank...

The great man from Tarsus: Freud on the apostle Paul.

PubMed

Westerink, Herman

2007-01-01

The author describes developments in Freud's writings concerning his views on the apostle Paul. This development shows that Freud more and more clearly regarded Paul as a key figure in understanding the complex relationship between Judaism and Christianity--and also as a man who essentially has no comfortable place in either of these religions. For Freud, Paul was a unique figure, an analyst of the human character and of his own culture and religion--a Jew who tried to free himself and his people from the burden of the sense of guilt.

31. Photocopy of line illustration; originally published in William N. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

31. Photocopy of line illustration; originally published in William N. Carey, 'St. Paul Builds an Airport One Mile From Post Office,' Engineering News-Record, (August 21, 1930), figure 6, page 294; SHOWS CANTILEVERED ROOF-TRUSS SYSTEM OF MUNICIPAL HANGAR COMPLETED AT ST. PAUL MUNICIPAL AIRPORT IN 1930; THE STRUCTURAL DESIGN WAS BASED ON THAT OF THE NORTHWEST AIRWAYS HANGAR, EXCEPT FOR THE SUBSTITUTION OF BOWSTRING TRUSSES FOR TRAPEZOIDAL TRUSSES - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Multistep estimators of the between-study variance: The relationship with the Paule-Mandel estimator.

PubMed

van Aert, Robbie C M; Jackson, Dan

2018-04-26

A wide variety of estimators of the between-study variance are available in random-effects meta-analysis. Many, but not all, of these estimators are based on the method of moments. The DerSimonian-Laird estimator is widely used in applications, but the Paule-Mandel estimator is an alternative that is now recommended. Recently, DerSimonian and Kacker have developed two-step moment-based estimators of the between-study variance. We extend these two-step estimators so that multiple (more than two) steps are used. We establish the surprising result that the multistep estimator tends towards the Paule-Mandel estimator as the number of steps becomes large. Hence, the iterative scheme underlying our new multistep estimator provides a hitherto unknown relationship between two-step estimators and Paule-Mandel estimator. Our analysis suggests that two-step estimators are not necessarily distinct estimators in their own right; instead, they are quantities that are closely related to the usual iterative scheme that is used to calculate the Paule-Mandel estimate. The relationship that we establish between the multistep and Paule-Mandel estimator is another justification for the use of the latter estimator. Two-step and multistep estimators are perhaps best conceptualized as approximate Paule-Mandel estimators. © 2018 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd.

Paul's gospel and the rhetoric of apostolic rejection: A study of Galatians 1:15--17, 1 Corinthians 15:8, F. C. Baur, and the origins of Paul's Gentile mission

NASA Astrophysics Data System (ADS)

Mitchell, Matthew Wesley

This dissertation proposes a new understanding of Paul's Gentile mission and its relationship to his so-called "conversion." This dissertation examines the origins of Paul's mission to the Gentiles, and locates it in his claims to have been personally commissioned to undertake such a mission by Jesus. Specifically, I argue that it is the rejection of Paul's claim to be an apostle, a claim founded upon his "conversion" experience, that precipitates his mission to the Gentiles. In arguing this view, I draw upon Ferdinand Christian Baur's nineteenth century theories concerning both the unreliability of Acts as a historical source, and his proposal of a clear division between Paul and the other apostles. In establishing the methodological and theoretical framework of the dissertation, I discuss the "New Perspective on Paul" that has dominated New Testament scholarship over the past thirty years. My study is also informed methodologically by the growing interest in rhetorical criticism among biblical scholars, although the emphasis of this dissertation bears more of a resemblance to the approach of the New Rhetoric than the categories of classical, Greco-Roman rhetoric. The textual component of this work falls into two stages. The first contains a full examination of Paul's "conversion passages" in Galatians 1:15--17 and 1 Corinthians 15:8, attempting to situate these seemingly unusual self-descriptions in their cultural contexts. The second involves an examination of F. C. Baur's presentation of Paul, and the reception of Baur's views among biblical scholars throughout the years following his scholarly activity. This dissertation makes two claims, each of which can stand on its own as an important contribution to scholarship. My first claim is that components of Baur's work support my proposal concerning Paul's Gentile mission and his experience of apostolic rejection, and that this proposal has much to commend it as an explanation of a perennial scholarly puzzle. My second claim is methodological, as I demonstrate that scholarly writings about Paul and his modern interpreters are themselves exercises in argumentation, and thus are not to be accepted uncritically, or without close attention to the rhetorical practices they utilize.

Brittle failure of rock: A review and general linear criterion

NASA Astrophysics Data System (ADS)

Labuz, Joseph F.; Zeng, Feitao; Makhnenko, Roman; Li, Yuan

2018-07-01

A failure criterion typically is phenomenological since few models exist to theoretically derive the mathematical function. Indeed, a successful failure criterion is a generalization of experimental data obtained from strength tests on specimens subjected to known stress states. For isotropic rock that exhibits a pressure dependence on strength, a popular failure criterion is a linear equation in major and minor principal stresses, independent of the intermediate principal stress. A general linear failure criterion called Paul-Mohr-Coulomb (PMC) contains all three principal stresses with three material constants: friction angles for axisymmetric compression ϕc and extension ϕe and isotropic tensile strength V0. PMC provides a framework to describe a nonlinear failure surface by a set of planes "hugging" the curved surface. Brittle failure of rock is reviewed and multiaxial test methods are summarized. Equations are presented to implement PMC for fitting strength data and determining the three material parameters. A piecewise linear approximation to a nonlinear failure surface is illustrated by fitting two planes with six material parameters to form either a 6- to 12-sided pyramid or a 6- to 12- to 6-sided pyramid. The particular nature of the failure surface is dictated by the experimental data.

Optical Modeling Activities for the James Webb Space Telescope (JWST) Project. II; Determining Image Motion and Wavefront Error Over an Extended Field of View with a Segmented Optical System

NASA Technical Reports Server (NTRS)

Howard, Joseph M.; Ha, Kong Q.

2004-01-01

This is part two of a series on the optical modeling activities for JWST. Starting with the linear optical model discussed in part one, we develop centroid and wavefront error sensitivities for the special case of a segmented optical system such as JWST, where the primary mirror consists of 18 individual segments. Our approach extends standard sensitivity matrix methods used for systems consisting of monolithic optics, where the image motion is approximated by averaging ray coordinates at the image and residual wavefront error is determined with global tip/tilt removed. We develop an exact formulation using the linear optical model, and extend it to cover multiple field points for performance prediction at each instrument aboard JWST. This optical model is then driven by thermal and dynamic structural perturbations in an integrated modeling environment. Results are presented.

Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice

PubMed Central

Jain, Deepanshu; Momeni, Mojdeh; Krishnaiah, Mahesh; Anand, Sury; Singhal, Shashideep

2015-01-01

AIM: To evaluate the impact of reporting bowel preparation using Boston Bowel Preparation Scale (BBPS) in clinical practice. METHODS: The study was a prospective observational cohort study which enrolled subjects reporting for screening colonoscopy. All subjects received a gallon of polyethylene glycol as bowel preparation regimen. After colonoscopy the endoscopists determined quality of bowel preparation using BBPS. Segmental scores were combined to calculate composite BBPS. Site and size of the polyps detected was recorded. Pathology reports were reviewed to determine advanced adenoma detection rates (AADR). Segmental AADR’s were calculated and categorized based on the segmental BBPS to determine the differential impact of bowel prep on AADR. RESULTS: Three hundred and sixty subjects were enrolled in the study with a mean age of 59.2 years, 36.3% males and 63.8% females. Four subjects with incomplete colonoscopy due BBPS of 0 in any segment were excluded. Based on composite BBPS subjects were divided into 3 groups; Group-0 (poor bowel prep, BBPS 0-3) n = 26 (7.3%), Group-1 (Suboptimal bowel prep, BBPS 4-6) n = 121 (34%) and Group-2 (Adequate bowel prep, BBPS 7-9) n = 209 (58.7%). AADR showed a linear trend through Group-1 to 3; with an AADR of 3.8%, 14.8% and 16.7% respectively. Also seen was a linear increasing trend in segmental AADR with improvement in segmental BBPS. There was statistical significant difference between AADR among Group 0 and 2 (3.8% vs 16.7%, P < 0.05), Group 1 and 2 (14.8% vs 16.7%, P < 0.05) and Group 0 and 1 (3.8% vs 14.8%, P < 0.05). χ2 method was used to compute P value for determining statistical significance. CONCLUSION: Segmental AADRs correlate with segmental BBPS. It is thus valuable to report segmental BBPS in colonoscopy reports in clinical practice. PMID:25852286

Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice.

PubMed

Jain, Deepanshu; Momeni, Mojdeh; Krishnaiah, Mahesh; Anand, Sury; Singhal, Shashideep

2015-04-07

To evaluate the impact of reporting bowel preparation using Boston Bowel Preparation Scale (BBPS) in clinical practice. The study was a prospective observational cohort study which enrolled subjects reporting for screening colonoscopy. All subjects received a gallon of polyethylene glycol as bowel preparation regimen. After colonoscopy the endoscopists determined quality of bowel preparation using BBPS. Segmental scores were combined to calculate composite BBPS. Site and size of the polyps detected was recorded. Pathology reports were reviewed to determine advanced adenoma detection rates (AADR). Segmental AADR's were calculated and categorized based on the segmental BBPS to determine the differential impact of bowel prep on AADR. Three hundred and sixty subjects were enrolled in the study with a mean age of 59.2 years, 36.3% males and 63.8% females. Four subjects with incomplete colonoscopy due BBPS of 0 in any segment were excluded. Based on composite BBPS subjects were divided into 3 groups; Group-0 (poor bowel prep, BBPS 0-3) n = 26 (7.3%), Group-1 (Suboptimal bowel prep, BBPS 4-6) n = 121 (34%) and Group-2 (Adequate bowel prep, BBPS 7-9) n = 209 (58.7%). AADR showed a linear trend through Group-1 to 3; with an AADR of 3.8%, 14.8% and 16.7% respectively. Also seen was a linear increasing trend in segmental AADR with improvement in segmental BBPS. There was statistical significant difference between AADR among Group 0 and 2 (3.8% vs 16.7%, P < 0.05), Group 1 and 2 (14.8% vs 16.7%, P < 0.05) and Group 0 and 1 (3.8% vs 14.8%, P < 0.05). χ(2) method was used to compute P value for determining statistical significance. Segmental AADRs correlate with segmental BBPS. It is thus valuable to report segmental BBPS in colonoscopy reports in clinical practice.

Bottlebrush-Guided Polymer Crystallization Resulting in Supersoft and Reversibly Moldable Physical Networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel, William F. M.; Xie, Guojun; Vatankhah Varnoosfaderani, Mohammad

The goal of this study is to use ABA triblock copolymers with central bottlebrush B segments and crystalline linear chain A segments to demonstrate the effect of side chains on the formation and mechanical properties of physical networks cross-linked by crystallites. For this purpose, a series of bottlebrush copolymers was synthesized consisting of central amorphous bottlebrush polymer segments with a varying degree of polymerization (DP) of poly(n-butyl acrylate) (PnBA) side chains and linear tail blocks of crystallizable poly(octadecyl acrylate-stat-docosyl acrylate) (poly(ODA-stat-DA)). The materials were generated by sequential atom transfer radical polymerization (ATRP) steps starting with a series of bifunctional macroinitiatorsmore » followed by the growth of two ODA-stat-DA linear-chain tails and eventually growing poly(nBA) side chains with increasing DPs. Crystallization of the poly(ODA-stat-DA) tails resulted in a series of reversible physical networks with bottlebrush strands bridging crystalline cross-links. They displayed very low moduli of elasticity of the order of 10 3–10 4 Pa. These distinct properties are due to the bottlebrush architecture, wherein densely grafted side chains play a dual role by facilitating disentanglement of the network strands and confining crystallization of the linear-chain tails. This combination leads to physical cross-linking of supersoft networks without percolation of the crystalline phase. The cross-link density was effectively controlled by the DP of the side chains with respect to the DP of the linear tails (n A). Furthermore, shorter side chains allowed for crystallization of the linear tails of neighboring bottlebrushes, while steric repulsion between longer side chains hindered the phase separation and crystallization process and prevented network formation.« less

Bottlebrush-Guided Polymer Crystallization Resulting in Supersoft and Reversibly Moldable Physical Networks

DOE PAGES

Daniel, William F. M.; Xie, Guojun; Vatankhah Varnoosfaderani, Mohammad; ...

2017-02-24

The goal of this study is to use ABA triblock copolymers with central bottlebrush B segments and crystalline linear chain A segments to demonstrate the effect of side chains on the formation and mechanical properties of physical networks cross-linked by crystallites. For this purpose, a series of bottlebrush copolymers was synthesized consisting of central amorphous bottlebrush polymer segments with a varying degree of polymerization (DP) of poly(n-butyl acrylate) (PnBA) side chains and linear tail blocks of crystallizable poly(octadecyl acrylate-stat-docosyl acrylate) (poly(ODA-stat-DA)). The materials were generated by sequential atom transfer radical polymerization (ATRP) steps starting with a series of bifunctional macroinitiatorsmore » followed by the growth of two ODA-stat-DA linear-chain tails and eventually growing poly(nBA) side chains with increasing DPs. Crystallization of the poly(ODA-stat-DA) tails resulted in a series of reversible physical networks with bottlebrush strands bridging crystalline cross-links. They displayed very low moduli of elasticity of the order of 10 3–10 4 Pa. These distinct properties are due to the bottlebrush architecture, wherein densely grafted side chains play a dual role by facilitating disentanglement of the network strands and confining crystallization of the linear-chain tails. This combination leads to physical cross-linking of supersoft networks without percolation of the crystalline phase. The cross-link density was effectively controlled by the DP of the side chains with respect to the DP of the linear tails (n A). Furthermore, shorter side chains allowed for crystallization of the linear tails of neighboring bottlebrushes, while steric repulsion between longer side chains hindered the phase separation and crystallization process and prevented network formation.« less

Segmentation of human upper body movement using multiple IMU sensors.

PubMed

Aoki, Takashi; Lin, Jonathan Feng-Shun; Kulic, Dana; Venture, Gentiane

2016-08-01

This paper proposes an approach for the segmentation of human body movements measured by inertial measurement unit sensors. Using the angular velocity and linear acceleration measurements directly, without converting to joint angles, we perform segmentation by formulating the problem as a classification problem, and training a classifier to differentiate between motion end-point and within-motion points. The proposed approach is validated with experiments measuring the upper body movement during reaching tasks, demonstrating classification accuracy of over 85.8%.

Hippocampal unified multi-atlas network (HUMAN): protocol and scale validation of a novel segmentation tool.

PubMed

Amoroso, N; Errico, R; Bruno, S; Chincarini, A; Garuccio, E; Sensi, F; Tangaro, S; Tateo, A; Bellotti, R

2015-11-21

In this study we present a novel fully automated Hippocampal Unified Multi-Atlas-Networks (HUMAN) algorithm for the segmentation of the hippocampus in structural magnetic resonance imaging. In multi-atlas approaches atlas selection is of crucial importance for the accuracy of the segmentation. Here we present an optimized method based on the definition of a small peri-hippocampal region to target the atlas learning with linear and non-linear embedded manifolds. All atlases were co-registered to a data driven template resulting in a computationally efficient method that requires only one test registration. The optimal atlases identified were used to train dedicated artificial neural networks whose labels were then propagated and fused to obtain the final segmentation. To quantify data heterogeneity and protocol inherent effects, HUMAN was tested on two independent data sets provided by the Alzheimer's Disease Neuroimaging Initiative and the Open Access Series of Imaging Studies. HUMAN is accurate and achieves state-of-the-art performance (Dice[Formula: see text] and Dice[Formula: see text]). It is also a robust method that remains stable when applied to the whole hippocampus or to sub-regions (patches). HUMAN also compares favorably with a basic multi-atlas approach and a benchmark segmentation tool such as FreeSurfer.

Hippocampal unified multi-atlas network (HUMAN): protocol and scale validation of a novel segmentation tool

NASA Astrophysics Data System (ADS)

Amoroso, N.; Errico, R.; Bruno, S.; Chincarini, A.; Garuccio, E.; Sensi, F.; Tangaro, S.; Tateo, A.; Bellotti, R.; Alzheimers Disease Neuroimaging Initiative,the

2015-11-01

In this study we present a novel fully automated Hippocampal Unified Multi-Atlas-Networks (HUMAN) algorithm for the segmentation of the hippocampus in structural magnetic resonance imaging. In multi-atlas approaches atlas selection is of crucial importance for the accuracy of the segmentation. Here we present an optimized method based on the definition of a small peri-hippocampal region to target the atlas learning with linear and non-linear embedded manifolds. All atlases were co-registered to a data driven template resulting in a computationally efficient method that requires only one test registration. The optimal atlases identified were used to train dedicated artificial neural networks whose labels were then propagated and fused to obtain the final segmentation. To quantify data heterogeneity and protocol inherent effects, HUMAN was tested on two independent data sets provided by the Alzheimer’s Disease Neuroimaging Initiative and the Open Access Series of Imaging Studies. HUMAN is accurate and achieves state-of-the-art performance (Dice{{}\\text{ADNI}} =0.929+/- 0.003 and Dice{{}\\text{OASIS}} =0.869+/- 0.002 ). It is also a robust method that remains stable when applied to the whole hippocampus or to sub-regions (patches). HUMAN also compares favorably with a basic multi-atlas approach and a benchmark segmentation tool such as FreeSurfer.

Spectral-spatial classification of hyperspectral data with mutual information based segmented stacked autoencoder approach

NASA Astrophysics Data System (ADS)

Paul, Subir; Nagesh Kumar, D.

2018-04-01

Hyperspectral (HS) data comprises of continuous spectral responses of hundreds of narrow spectral bands with very fine spectral resolution or bandwidth, which offer feature identification and classification with high accuracy. In the present study, Mutual Information (MI) based Segmented Stacked Autoencoder (S-SAE) approach for spectral-spatial classification of the HS data is proposed to reduce the complexity and computational time compared to Stacked Autoencoder (SAE) based feature extraction. A non-parametric dependency measure (MI) based spectral segmentation is proposed instead of linear and parametric dependency measure to take care of both linear and nonlinear inter-band dependency for spectral segmentation of the HS bands. Then morphological profiles are created corresponding to segmented spectral features to assimilate the spatial information in the spectral-spatial classification approach. Two non-parametric classifiers, Support Vector Machine (SVM) with Gaussian kernel and Random Forest (RF) are used for classification of the three most popularly used HS datasets. Results of the numerical experiments carried out in this study have shown that SVM with a Gaussian kernel is providing better results for the Pavia University and Botswana datasets whereas RF is performing better for Indian Pines dataset. The experiments performed with the proposed methodology provide encouraging results compared to numerous existing approaches.

Automatic optimal filament segmentation with sub-pixel accuracy using generalized linear models and B-spline level-sets.

PubMed

Xiao, Xun; Geyer, Veikko F; Bowne-Anderson, Hugo; Howard, Jonathon; Sbalzarini, Ivo F

2016-08-01

Biological filaments, such as actin filaments, microtubules, and cilia, are often imaged using different light-microscopy techniques. Reconstructing the filament curve from the acquired images constitutes the filament segmentation problem. Since filaments have lower dimensionality than the image itself, there is an inherent trade-off between tracing the filament with sub-pixel accuracy and avoiding noise artifacts. Here, we present a globally optimal filament segmentation method based on B-spline vector level-sets and a generalized linear model for the pixel intensity statistics. We show that the resulting optimization problem is convex and can hence be solved with global optimality. We introduce a simple and efficient algorithm to compute such optimal filament segmentations, and provide an open-source implementation as an ImageJ/Fiji plugin. We further derive an information-theoretic lower bound on the filament segmentation error, quantifying how well an algorithm could possibly do given the information in the image. We show that our algorithm asymptotically reaches this bound in the spline coefficients. We validate our method in comprehensive benchmarks, compare with other methods, and show applications from fluorescence, phase-contrast, and dark-field microscopy. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Multipole electrodynamic ion trap geometries for microparticle confinement under standard ambient temperature and pressure conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mihalcea, Bogdan M., E-mail: bogdan.mihalcea@inflpr.ro; Vişan, Gina T.; Ganciu, Mihai

2016-03-21

Trapping of microparticles and aerosols is of great interest for physics and chemistry. We report microparticle trapping in case of multipole linear Paul trap geometries, operating under standard ambient temperature and pressure conditions. An 8- and 12-electrode linear trap geometries have been designed and tested with an aim to achieve trapping for larger number of particles and to study microparticle dynamical stability in electrodynamic fields. We report emergence of planar and volume ordered structures of microparticles, depending on the a.c. trapping frequency and particle specific charge ratio. The electric potential within the trap is mapped using the electrolytic tank method.more » Particle dynamics is simulated using a stochastic Langevin equation. We emphasize extended regions of stable trapping with respect to quadrupole traps, as well as good agreement between experiment and numerical simulations.« less

Geochemistry of the mantle beneath the Rodriguez Triple Junction and the South-East Indian Ridge

NASA Astrophysics Data System (ADS)

Michard, A.; Montigny, R.; Schlich, R.

1986-05-01

Rare earth element abundances and Sr, Nd. Pb isotope compositions have been measured on zero-age dredge samples from the Rodriguez Triple Junction (RTJ) and the South-East Indian Ridge (SEIR), Along the SEIR. the geochemical "halo" of the St. Paul hot spot has a half-width of about 400 km and the data may be fairly well accounted for by a binary mixing between an Indian MORB-type component ( 87Sr/ 86Sr = 0.7028. 143Nd/ 144Nd = 0.51304. 206Pb/ 204Pb = 17.8) and the plume-type St. Paul component (0.7036, 0.5129, and 18.7 respectively). The alignment of the lead isotope data is particularly good with an apparent age of 1.95 ± 0.13 Ga and Th/U source value of 3.94. One sample dredged on the ridge 60 km southeast of St. Paul bears a definite Kerguelen isotopic signature. The RTJ has distinctive geochemical properties which contrast with those of the adjacent ridge segments. Low 206Pb/ 204Pb ratios which plots to the left of the geochron, rather high 208Pb/ 204Pb and 87Sr/ 87Sr ratios (17.4. 37.4, and 0.7031 respectively), a striking isotopic homogeneity, and variable LREE/HREE fractionation with (La/Sm) N, = 0.3-0.8 make this triple junction an anomalous site. The geochemical properties of the Indian Ocean basats have been examined using a three-component mantle model involving (a) a normal MORB-type source though to represent the depleted upper mantle matrix, (b) an OIB-type source of uncertain parentage (recycled oceanic crust?), and (c) a component with low μ. low Sm/Nd. high Rb/Sr (time-averaged value) which is tentatively assigned to ancient hydrothermal and abyssal sediments recycled in the mantle. The high 208Pb/ 204Pb and 87Sr/ 86Sr ratios typical of the Dupal anomaly are likely due to the widespread distribution of this latter component in the basalt source from this area. including that for MORBs.

White Matter Tract Segmentation as Multiple Linear Assignment Problems

PubMed Central

Sharmin, Nusrat; Olivetti, Emanuele; Avesani, Paolo

2018-01-01

Diffusion magnetic resonance imaging (dMRI) allows to reconstruct the main pathways of axons within the white matter of the brain as a set of polylines, called streamlines. The set of streamlines of the whole brain is called the tractogram. Organizing tractograms into anatomically meaningful structures, called tracts, is known as the tract segmentation problem, with important applications to neurosurgical planning and tractometry. Automatic tract segmentation techniques can be unsupervised or supervised. A common criticism of unsupervised methods, like clustering, is that there is no guarantee to obtain anatomically meaningful tracts. In this work, we focus on supervised tract segmentation, which is driven by prior knowledge from anatomical atlases or from examples, i.e., segmented tracts from different subjects. We present a supervised tract segmentation method that segments a given tract of interest in the tractogram of a new subject using multiple examples as prior information. Our proposed tract segmentation method is based on the idea of streamline correspondence i.e., on finding corresponding streamlines across different tractograms. In the literature, streamline correspondence has been addressed with the nearest neighbor (NN) strategy. Differently, here we formulate the problem of streamline correspondence as a linear assignment problem (LAP), which is a cornerstone of combinatorial optimization. With respect to the NN, the LAP introduces a constraint of one-to-one correspondence between streamlines, that forces the correspondences to follow the local anatomical differences between the example and the target tract, neglected by the NN. In the proposed solution, we combined the Jonker-Volgenant algorithm (LAPJV) for solving the LAP together with an efficient way of computing the nearest neighbors of a streamline, which massively reduces the total amount of computations needed to segment a tract. Moreover, we propose a ranking strategy to merge correspondences coming from different examples. We validate the proposed method on tractograms generated from the human connectome project (HCP) dataset and compare the segmentations with the NN method and the ROI-based method. The results show that LAP-based segmentation is vastly more accurate than ROI-based segmentation and substantially more accurate than the NN strategy. We provide a Free/OpenSource implementation of the proposed method. PMID:29467600

White Matter Tract Segmentation as Multiple Linear Assignment Problems.

PubMed

Sharmin, Nusrat; Olivetti, Emanuele; Avesani, Paolo

2017-01-01

Diffusion magnetic resonance imaging (dMRI) allows to reconstruct the main pathways of axons within the white matter of the brain as a set of polylines, called streamlines. The set of streamlines of the whole brain is called the tractogram. Organizing tractograms into anatomically meaningful structures, called tracts, is known as the tract segmentation problem, with important applications to neurosurgical planning and tractometry. Automatic tract segmentation techniques can be unsupervised or supervised. A common criticism of unsupervised methods, like clustering, is that there is no guarantee to obtain anatomically meaningful tracts. In this work, we focus on supervised tract segmentation, which is driven by prior knowledge from anatomical atlases or from examples, i.e., segmented tracts from different subjects. We present a supervised tract segmentation method that segments a given tract of interest in the tractogram of a new subject using multiple examples as prior information. Our proposed tract segmentation method is based on the idea of streamline correspondence i.e., on finding corresponding streamlines across different tractograms. In the literature, streamline correspondence has been addressed with the nearest neighbor (NN) strategy. Differently, here we formulate the problem of streamline correspondence as a linear assignment problem (LAP), which is a cornerstone of combinatorial optimization. With respect to the NN, the LAP introduces a constraint of one-to-one correspondence between streamlines, that forces the correspondences to follow the local anatomical differences between the example and the target tract, neglected by the NN. In the proposed solution, we combined the Jonker-Volgenant algorithm (LAPJV) for solving the LAP together with an efficient way of computing the nearest neighbors of a streamline, which massively reduces the total amount of computations needed to segment a tract. Moreover, we propose a ranking strategy to merge correspondences coming from different examples. We validate the proposed method on tractograms generated from the human connectome project (HCP) dataset and compare the segmentations with the NN method and the ROI-based method. The results show that LAP-based segmentation is vastly more accurate than ROI-based segmentation and substantially more accurate than the NN strategy. We provide a Free/OpenSource implementation of the proposed method.

[A micro-silicon multi-slit spectrophotometer based on MEMS technology].

PubMed

Hao, Peng; Wu, Yi-Hui; Zhang, Ping; Liu, Yong-Shun; Zhang, Ke; Li, Hai-Wen

2009-06-01

A new mini-spectrophotometer was developed by adopting micro-silicon slit and pixel segmentation technology, and this spectrophotometer used photoelectron diode array as the detector by the back-dividing-light way. At first, the effect of the spectral bandwidth on the tested absorbance linear correlation was analyzed. A theory for the design of spectrophotometer's slit was brought forward after discussing the relationships between spectrophotometer spectrum band width and pre-and post-slits width. Then, the integrative micro-silicon-slit, which features small volume, high precision, and thin thickness, was manufactured based on the MEMS technology. Finally, a test was carried on linear absorbance solution by this spectrophotometer. The final result showed that the correlation coefficients were larger than 0.999, which means that the new mini-spectrophotometer with micro-silicon slit pixel segmentation has an obvious linear correlation.

A boosted optimal linear learner for retinal vessel segmentation

NASA Astrophysics Data System (ADS)

Poletti, E.; Grisan, E.

2014-03-01

Ocular fundus images provide important information about retinal degeneration, which may be related to acute pathologies or to early signs of systemic diseases. An automatic and quantitative assessment of vessel morphological features, such as diameters and tortuosity, can improve clinical diagnosis and evaluation of retinopathy. At variance with available methods, we propose a data-driven approach, in which the system learns a set of optimal discriminative convolution kernels (linear learner). The set is progressively built based on an ADA-boost sample weighting scheme, providing seamless integration between linear learner estimation and classification. In order to capture the vessel appearance changes at different scales, the kernels are estimated on a pyramidal decomposition of the training samples. The set is employed as a rotating bank of matched filters, whose response is used by the boosted linear classifier to provide a classification of each image pixel into the two classes of interest (vessel/background). We tested the approach fundus images available from the DRIVE dataset. We show that the segmentation performance yields an accuracy of 0.94.

72. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

72. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, June 25, 1958. #31024. Photographer: St. Paul Dispatch-Pioneer Press. VIEW TO SOUTH, SHOWING THE RESURFACING OF THE BRIDGE IN 1958 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

64. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

64. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul Minnesota, ca. 1891. #35805. Photographer: Haynes and Bros., St. Paul.) VIEW TO SOUTH, SHOWING FOUR PERCENT GRADE OF HIGH BRIDGE, ca. 1981 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

76 FR 18725 - Marine Mammals; File Nos. 14330 and 14335

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-05

... (Phoca vitulina) on St. Paul, St. George, Otter, and Walrus Islands, and Sea Lion Rock, all of the... marine mammals in Alaska: (File No. 14330) the Aleut Community of St. Paul Island, Tribal Government, Ecosystem Conservation Office, St. Paul Island, AK; and (File No. 14335) the Alaska SeaLife Center, Seward...

In Conversation with Paul Richards

ERIC Educational Resources Information Center

Holman, Andrew

2013-01-01

Paul Richards is one of those individuals who make a difference and is as far from institutional as one can be. The author met up with him at the Learning Disability Today conference in London to talk more about his work and life. Paul coordinates the service user involvement across Southdown Housing Association, based in Sussex.

76 FR 9278 - Safety Zone; Fourth Annual Offshore Challenge, Sunny Isles Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

... Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A.Steiner@uscg.mil . If you have questions on viewing or submitting material to the docket, call.... Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535- 8724, e-mail Paul.A.Steiner...

75 FR 77899 - Notice of Inventory Completion: Minnesota Indian Affairs Council, St. Paul and Bemidji, MN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-14

... DEPARTMENT OF THE INTERIOR National Park Service [2253-665] Notice of Inventory Completion: Minnesota Indian Affairs Council, St. Paul and Bemidji, MN AGENCY: National Park Service, Interior. ACTION... funerary objects in the possession of the Minnesota Indian Affairs Council, St. Paul and Bemidji, MN. The...

Paul Torcellini | NREL

Science.gov Websites

| 303-384-7528 Paul is the principal engineer for the Commercial Buildings Research Group and has been at the NREL for 19 years. Prior to this role, he was the group manager for the Commercial Buildings articles related to energy efficiency and zero-energy commercial buildings. Among his many awards, Paul has

75 FR 34670 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Revision to Emission...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

... Promulgation of Air Quality Implementation Plans; Maryland; Revision to Emission Limitations for R. Paul Smith... revision pertains to revised emission limitations for the R. Paul Smith Power Station located in Washington... R. Paul Smith Power Station in Washington County. This facility had annual nitrogen oxides (NOx...

Paul Voosen Receives 2013 David Perlman Award for Excellence in Science Journalism—News: Citation

NASA Astrophysics Data System (ADS)

Zaneski, Cyril T.

2014-01-01

It's my pleasure to nominate Paul Voosen, the former science reporter for Greenwire, for the David Perlman award. Last November, as Superstorm Sandy pounded the East Coast of the United States, Paul found himself stranded for several days in Miami, mourning a recently deceased family member.

78 FR 59317 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Revision to Emission...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

... for R. Paul Smith Power Station; Withdrawal of Proposed Rule AGENCY: Environmental Protection Agency... revision pertains to revised emission limitations for the R. Paul Smith Power Station located in Washington... action to approve the revised emission limitations for the R. Paul Smith Power Station contained in the...

The Incalculable Benefits of Revitalizing Your Board

ERIC Educational Resources Information Center

Holtschneider, Dennis H.

2013-01-01

DePaul University has grown in size and stature in the last decade. Chicago's "little school under the El," as DePaul was once known, is now the nation's largest Catholic university and the largest private, nonprofit university in the Midwest. DePaul University restructured its board, enabling it to play an important role in the…

78 FR 29612 - Prevailing Rate Systems; Redefinition of the Minneapolis-St. Paul, MN, and Southwestern Wisconsin...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-21

... OFFICE OF PERSONNEL MANAGEMENT 5 CFR Part 532 RIN 3206-AM75 Prevailing Rate Systems; Redefinition of the Minneapolis-St. Paul, MN, and Southwestern Wisconsin Appropriated Fund Federal Wage System.... Paul, MN, and Southwestern Wisconsin appropriated fund Federal Wage System (FWS) wage areas. The final...

Partnering for Environmental Security Cooperation in Central Asia and the Caspian Basin

DTIC Science & Technology

2002-04-01

Organizations.......................................................................................98 Mr. Paul Giannone Disaster Response Planning Processes...Paul Giannone of CARE USA who discussed key points of Non-governmental Organizations’ relationships with the military and provided suggestions on...Relationships between Military and Civilian Organizations Mr. Paul Giannone Disaster Response Planning Processes and Procedures Mr. Wolfgang G

MEMS earthworm: a thermally actuated peristaltic linear micromotor

NASA Astrophysics Data System (ADS)

Arthur, Craig; Ellerington, Neil; Hubbard, Ted; Kujath, Marek

2011-03-01

This paper examines the design, fabrication and testing of a bio-mimetic MEMS (micro-electro mechanical systems) earthworm motor with external actuators. The motor consists of a passive mobile shuttle with two flexible diamond-shaped segments; each segment is independently squeezed by a pair of stationary chevron-shaped thermal actuators. Applying a specific sequence of squeezes to the earthworm segments, the shuttle can be driven backward or forward. Unlike existing inchworm drives that use clamping and thrusting actuators, the earthworm actuators apply only clamping forces to the shuttle, and lateral thrust is produced by the shuttle's compliant geometry. The earthworm assembly is fabricated using the PolyMUMPs process with planar dimensions of 400 µm width by 800 µm length. The stationary actuators operate within the range of 4-9 V and provide a maximum shuttle range of motion of 350 µm (approximately half its size), a maximum shuttle speed of 17 mm s-1 at 10 kHz, and a maximum dc shuttle force of 80 µN. The shuttle speed was found to vary linearly with both input voltage and input frequency. The shuttle force was found to vary linearly with the actuator voltage.

Reprint of Solution of Ambrosio-Tortorelli model for image segmentation by generalized relaxation method

NASA Astrophysics Data System (ADS)

D'Ambra, Pasqua; Tartaglione, Gaetano

2015-04-01

Image segmentation addresses the problem to partition a given image into its constituent objects and then to identify the boundaries of the objects. This problem can be formulated in terms of a variational model aimed to find optimal approximations of a bounded function by piecewise-smooth functions, minimizing a given functional. The corresponding Euler-Lagrange equations are a set of two coupled elliptic partial differential equations with varying coefficients. Numerical solution of the above system often relies on alternating minimization techniques involving descent methods coupled with explicit or semi-implicit finite-difference discretization schemes, which are slowly convergent and poorly scalable with respect to image size. In this work we focus on generalized relaxation methods also coupled with multigrid linear solvers, when a finite-difference discretization is applied to the Euler-Lagrange equations of Ambrosio-Tortorelli model. We show that non-linear Gauss-Seidel, accelerated by inner linear iterations, is an effective method for large-scale image analysis as those arising from high-throughput screening platforms for stem cells targeted differentiation, where one of the main goal is segmentation of thousand of images to analyze cell colonies morphology.

Solution of Ambrosio-Tortorelli model for image segmentation by generalized relaxation method

NASA Astrophysics Data System (ADS)

D'Ambra, Pasqua; Tartaglione, Gaetano

2015-03-01

Image segmentation addresses the problem to partition a given image into its constituent objects and then to identify the boundaries of the objects. This problem can be formulated in terms of a variational model aimed to find optimal approximations of a bounded function by piecewise-smooth functions, minimizing a given functional. The corresponding Euler-Lagrange equations are a set of two coupled elliptic partial differential equations with varying coefficients. Numerical solution of the above system often relies on alternating minimization techniques involving descent methods coupled with explicit or semi-implicit finite-difference discretization schemes, which are slowly convergent and poorly scalable with respect to image size. In this work we focus on generalized relaxation methods also coupled with multigrid linear solvers, when a finite-difference discretization is applied to the Euler-Lagrange equations of Ambrosio-Tortorelli model. We show that non-linear Gauss-Seidel, accelerated by inner linear iterations, is an effective method for large-scale image analysis as those arising from high-throughput screening platforms for stem cells targeted differentiation, where one of the main goal is segmentation of thousand of images to analyze cell colonies morphology.

Square-wave stripping voltammetric determination of caffeic acid on electrochemically reduced graphene oxide-Nafion composite film.

PubMed

Filik, Hayati; Çetintaş, Gamze; Avan, Asiye Aslıhan; Aydar, Sevda; Koç, Serkan Naci; Boz, İsmail

2013-11-15

An electrochemical sensor composed of Nafion-graphene nanocomposite film for the voltammetric determination of caffeic acid (CA) was studied. A Nafion graphene oxide-modified glassy carbon electrode was fabricated by a simple drop-casting method and then graphene oxide was electrochemically reduced over the glassy carbon electrode. The electrochemical analysis method was based on the adsorption of caffeic acid on Nafion/ER-GO/GCE and then the oxidation of CA during the stripping step. The resulting electrode showed an excellent electrocatalytical response to the oxidation of caffeic acid (CA). The electrochemistry of caffeic acid on Nafion/ER-GO modified glassy carbon electrodes (GCEs) were studied by cyclic voltammetry and square-wave adsorption stripping voltammetry (SW-AdSV). At optimized test conditions, the calibration curve for CA showed two linear segments: the first linear segment increased from 0.1 to 1.5 and second linear segment increased up to 10 µM. The detection limit was determined as 9.1×10(-8) mol L(-1) using SW-AdSV. Finally, the proposed method was successfully used to determine CA in white wine samples. Copyright © 2013 Elsevier B.V. All rights reserved.

Selecting exposure measures in crash rate prediction for two-lane highway segments.

PubMed

Qin, Xiao; Ivan, John N; Ravishanker, Nalini

2004-03-01

A critical part of any risk assessment is identifying how to represent exposure to the risk involved. Recent research shows that the relationship between crash count and traffic volume is non-linear; consequently, a simple crash rate computed as the ratio of crash count to volume is not proper for comparing the safety of sites with different traffic volumes. To solve this problem, we describe a new approach for relating traffic volume and crash incidence. Specifically, we disaggregate crashes into four types: (1) single-vehicle, (2) multi-vehicle same direction, (3) multi-vehicle opposite direction, and (4) multi-vehicle intersecting, and define candidate exposure measures for each that we hypothesize will be linear with respect to each crash type. This paper describes initial investigation using crash and physical characteristics data for highway segments in Michigan from the Highway Safety Information System (HSIS). We use zero-inflated-Poisson (ZIP) modeling to estimate models for predicting counts for each of the above crash types as a function of the daily volume, segment length, speed limit and roadway width. We found that the relationship between crashes and the daily volume (AADT) is non-linear and varies by crash type, and is significantly different from the relationship between crashes and segment length for all crash types. Our research will provide information to improve accuracy of crash predictions and, thus, facilitate more meaningful comparison of the safety record of seemingly similar highway locations.

Finite grade pheromone ant colony optimization for image segmentation

NASA Astrophysics Data System (ADS)

Yuanjing, F.; Li, Y.; Liangjun, K.

2008-06-01

By combining the decision process of ant colony optimization (ACO) with the multistage decision process of image segmentation based on active contour model (ACM), an algorithm called finite grade ACO (FACO) for image segmentation is proposed. This algorithm classifies pheromone into finite grades and updating of the pheromone is achieved by changing the grades and the updated quantity of pheromone is independent from the objective function. The algorithm that provides a new approach to obtain precise contour is proved to converge to the global optimal solutions linearly by means of finite Markov chains. The segmentation experiments with ultrasound heart image show the effectiveness of the algorithm. Comparing the results for segmentation of left ventricle images shows that the ACO for image segmentation is more effective than the GA approach and the new pheromone updating strategy appears good time performance in optimization process.

Segmentation of discrete vector fields.

PubMed

Li, Hongyu; Chen, Wenbin; Shen, I-Fan

2006-01-01

In this paper, we propose an approach for 2D discrete vector field segmentation based on the Green function and normalized cut. The method is inspired by discrete Hodge Decomposition such that a discrete vector field can be broken down into three simpler components, namely, curl-free, divergence-free, and harmonic components. We show that the Green Function Method (GFM) can be used to approximate the curl-free and the divergence-free components to achieve our goal of the vector field segmentation. The final segmentation curves that represent the boundaries of the influence region of singularities are obtained from the optimal vector field segmentations. These curves are composed of piecewise smooth contours or streamlines. Our method is applicable to both linear and nonlinear discrete vector fields. Experiments show that the segmentations obtained using our approach essentially agree with human perceptual judgement.

Detailing magnetic field strength dependence and segmental artifact distribution of myocardial effective transverse relaxation rate at 1.5, 3.0, and 7.0 T.

PubMed

Meloni, Antonella; Hezel, Fabian; Positano, Vincenzo; Keilberg, Petra; Pepe, Alessia; Lombardi, Massimo; Niendorf, Thoralf

2014-06-01

Realizing the challenges and opportunities of effective transverse relaxation rate (R2 *) mapping at high and ultrahigh fields, this work examines magnetic field strength (B0 ) dependence and segmental artifact distribution of myocardial R2 * at 1.5, 3.0, and 7.0 T. Healthy subjects were considered. Three short-axis views of the left ventricle were examined. R2 * was calculated for 16 standard myocardial segments. Global and mid-septum R2 * were determined. For each segment, an artifactual factor was estimated as the deviation of segmental from global R2 * value. The global artifactual factor was significantly enlarged at 7.0 T versus 1.5 T (P = 0.010) but not versus 3.0 T. At 7.0 T, the most severe susceptibility artifacts were detected in the inferior lateral wall. The mid-septum showed minor artifactual factors at 7.0 T, similar to those at 1.5 and 3.0 T. Mean R2 * increased linearly with the field strength, with larger changes for global heart R2 * values. At 7.0 T, segmental heart R2 * analysis is challenging due to macroscopic susceptibility artifacts induced by the heart-lung interface and the posterior vein. Myocardial R2 * depends linearly on the magnetic field strength. The increased R2 * sensitivity at 7.0 T might offer means for susceptibility-weighted and oxygenation level-dependent MR imaging of the myocardium. Copyright © 2013 Wiley Periodicals, Inc.

NOTE: Reducing the number of segments in unidirectional MLC segmentations

NASA Astrophysics Data System (ADS)

Mellado, X.; Cruz, S.; Artacho, J. M.; Canellas, M.

2010-02-01

In intensity-modulated radiation therapy (IMRT), fluence matrices obtained from a treatment planning system are usually delivered by a linear accelerator equipped with a multileaf collimator (MLC). A segmentation method is needed for decomposing these fluence matrices into segments suitable for the MLC, and the number of segments used is an important factor for treatment time. In this work, an algorithm for reduction of the number of segments (NS) is presented for unidirectional segmentations, where there is no backtracking of the MLC leaves. It uses a geometrical representation of the segmentation output for searching the key values in a fluence matrix that complicate its decomposition. The NS reduction is achieved by performing minor modifications in these values, under the conditions of avoiding substantial modifications of the dose-volume histogram, and does not increase in average the total number of monitor units delivered. The proposed method was tested using two clinical cases planned with the PCRT 3D® treatment planning system.

75 FR 72964 - Determinations of Attainment by the Applicable Attainment Date for the Hayden, Nogales, Paul Spur...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [R09-OAR-2010-0718; FRL-9233-1] Determinations of Attainment by the Applicable Attainment Date for the Hayden, Nogales, Paul Spur/Douglas PM10 Nonattainment... November 2, 2010 (75 FR 67220), direct final rule determining that the Hayden, Nogales, and Paul Spur...

28. Photocopy of photograph dated ca. 1940; photographer unknown; original ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Photocopy of photograph dated ca. 1940; photographer unknown; original filed as MR2.9/SP8/r373 in Audio-Visual Collection of Minnesota Historical Society, St. Paul; WEST SIDE AFTER SECOND-STORY ADDITION; LOOKING EAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Religion in the Locker Room

ERIC Educational Resources Information Center

Price, Sean

2013-01-01

In September 2011, Paul Phillips stepped out of his football team's field house and into a struggle over the separation of church and state. Like most teams, Paul's practiced after school. But one day he found that the coach had called in a local minister to conduct a weekly half-hour "team chapel" before practice. Paul, who does not believe in…

76 FR 24840 - Safety Zone; 2011 Rohto Ironman 70.3 Miami, Biscayne Bay, Miami, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-03

... Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A.Steiner@uscg.mil . If you have questions on viewing or submitting material to the docket, call... Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail...

76 FR 34649 - Foreign-Trade Zone 119-Minneapolis-St. Paul, MN; Application for Reorganization Under Alternative...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-14

...--Minneapolis-St. Paul, MN; Application for Reorganization Under Alternative Site Framework An application has... current zone project includes the following sites: Site 1 (3,002 acres)--located at the Minneapolis-St...); Site 9 (20 acres)--1700 Wynne Avenue, St. Paul (Ramsey County); and, Site 10 (236 acres)-- Bloomington...

Paul D. Boyer, Adenosine Triphosphate (ATP), and the Binding Change

Science.gov Websites

-- October 1975, DOE Technical Report, 1975 A Perspective of the Binding Change Mechanism for ATP Synthesis Reports, Vol. 18, No. 3, 1998 ATP Synthesis and the Binding Change Mechanism: The Work of Paul D. Boyer Mechanism of ATP Synthesis Additional Web Pages: Adenosine Triphosphate: The Energy Currency of Life Paul D

78 FR 28633 - Prometric, Inc., a Subsidiary of Educational Testing Service, Including On-Site Leased Workers...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-15

... Subsidiary of Educational Testing Service, Including On-Site Leased Workers From Office Team St. Paul... Office Team were employed on-site at the St. Paul, Minnesota location of the subject firm. The Department... workers leased from Office Team working on- site at the St. Paul, Minnesota location of Prometric, Inc., a...

Riparian Land Use/Land Cover Data for Three Study Units in Group II of the Nutrient Enrichment Effects Topical Study of the National Water-Quality Assessment Program

USGS Publications Warehouse

Johnson, Michaela R.; Clark, Jimmy M.; Dickinson, Ross G.; Sanocki, Chris A.; Tranmer, Andrew W.

2009-01-01

This data set was developed as part of the National Water-Quality Assessment (NAWQA) Program, Nutrient Enrichment Effects Topical (NEET) study. This report is concerned with three of the eight NEET study units distributed across the United States: Ozark Plateaus, Upper Mississippi River Basin, and Upper Snake River Basin, collectively known as Group II of the NEET study. Ninety stream reaches were investigated during 2006-08 in these three study units. Stream segments, with lengths equal to the base-10 logarithm of the basin area, were delineated upstream from the stream reaches through the use of digital orthophoto quarter-quadrangle (DOQQ) imagery. The analysis area for each stream segment was defined by a streamside buffer extending laterally to 250 meters from the stream segment. Delineation of landuse and land-cover (LULC) map units within stream-segment buffers was completed using on-screen digitizing of riparian LULC classes interpreted from the DOQQ. LULC units were classified using a strategy consisting of nine classes. National Wetlands Inventory (NWI) data were used to aid in wetland classification. Longitudinal riparian transects (lines offset from the stream segments) were generated digitally, used to sample the LULC maps, and partitioned in accord with the intersected LULC map-unit types. These longitudinal samples yielded the relative linear extent and sequence of each LULC type within the riparian zone at the segment scale. The resulting areal and linear estimates of LULC extent filled in the spatial-scale gap between the 30-meter resolution of the 1990s National Land Cover Dataset and the reach-level habitat assessment data collected onsite routinely for NAWQA ecological sampling. The resulting data consisted of 12 geospatial data sets: LULC within 25 meters of the stream reach (polygon); LULC within 50 meters of the stream reach (polygon); LULC within 50 meters of the stream segment (polygon); LULC within 100 meters of the stream segment (polygon); LULC within 150 meters of the stream segment (polygon); LULC within 250 meters of the stream segment (polygon); frequency of gaps in woody vegetation at the reach scale (arc); stream reaches (arc); longitudinal LULC transect sample at the reach scale (arc); frequency of gaps in woody vegetation at the segment scale (arc); stream segments (arc); and longitudinal LULC transect sample at the segment scale (arc).

26. Photocopy of photograph dated 1930; photographer unknown; original filed ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Photocopy of photograph dated 1930; photographer unknown; original filed as MR2.9/SP8/p343 in Audio-Visual Collection of Minnesota Historical Society, St. Paul; THREE-QUARTER VIEW SHOWING WEST SIDE AND SOUTH FRONT SHORTLY AFTER COMPLETION; LOOKING NORTHEAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

27. Photocopy of photograph dated ca. 1940; photographer unknown; original ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

27. Photocopy of photograph dated ca. 1940; photographer unknown; original filed as MR2.9/SP8/r374 in Audio-Visual Collection Minnesota Historical Society, St. Paul; THREE-QUARTER VIEW SHOWING WEST SIDE AND SOUTH FRONT AFTER SECOND-STORY ADDITION; LOOKING NORTHEAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Ultrasonically Activated Diffusion Bonding for Fluidic Control Assembly

DTIC Science & Technology

1979-02-01

CONTROL ASSEMBLY SONOBOND CORPORATION SUBSIDIARY OF CHRISTIAN METALS CORPORATION WEST CHESTER, PENNSYLVANIA HOWARD A. SCHEETZ PAUL L. COPPA JANET...FLUIDIC CONTROL ASSEMBLY Howard A. Scheetz Paul L. Coppa Janet Devine Sonobond Corporation Subsidiary of Christiana Metals Corporation West... Paul L. Coppa Janet Devine fl. CONTRACT OR GRANT NUMBERS.) Contract No. DAAA21-76-C-0136 ». PERFORMING ORGANIZATION N AM t AND ADDRESS

Paul of Tarsus: The Ancient Model of "Parrhesia" or Freedom of Speech.

ERIC Educational Resources Information Center

Keefe, Carolyn

The word "parrhesia" is of Greek origin and indicates the right to say anything a person chooses. The Apostle Paul was himself an operational definition of parrhesia, and a term that symbolizes such a controlling force on such a significant figure is worthy of examination and academic study. For Paul, his work as an evangelist and pastor was a…

A simulation study for determination of refractive index dispersion of dielectric film from reflectance spectrum by using Paul wavelet

NASA Astrophysics Data System (ADS)

Tiryaki, Erhan; Coşkun, Emre; Kocahan, Özlem; Özder, Serhat

2017-02-01

In this work, the Continuous Wavelet Transform (CWT) with Paul wavelet was improved as a tool for determination of refractive index dispersion of dielectric film by using the reflectance spectrum of the film. The reflectance spectrum was generated theoretically in the range of 0.8333 - 3.3333 μm wavenumber and it was analyzed with presented method. Obtained refractive index determined from various resolution of Paul wavelet were compared with the input values, and the importance of the tunable resolution with Paul wavelet was discussed briefly. The noise immunity and uncertainty of the method was also studied.

Boundary control by displacement at one end of a string and the integral condition on the other

NASA Astrophysics Data System (ADS)

Attaev, Anatoly Kh.

2017-09-01

For a one-dimensional wave equation we study the problem of finding such boundary controls that makes a string move from an arbitrary specified initial state to an arbitrary specified final state. The control is applied at the left end of the string while the nonlocal displacement is at the right end. Necessary and sufficient conditions are established for the functions determining the initial and final state of the string. An explicit analytical form of the boundary control is obtained as well as the minimum time T = l for this control. In case when T = l - ɛ, 0 < ɛ < l, i.e. T < l it is shown the initial values u(x, 0) = ϕ(x) and ut (x, 0) = ψ(x) cannot be set arbitrary. Moreover, if ɛ < l/2, hence the functions ϕ(x) and ψ(x) are linearly dependent on any segment of finite length either in the segment [0, ɛ], or in [l-ɛ, l]. Suppose ɛ ≥ l/2, then functions ϕ(x) and ψ(x) are linearly dependent on any segment of finite length in the segment [0, l].

An improved FSL-FIRST pipeline for subcortical gray matter segmentation to study abnormal brain anatomy using quantitative susceptibility mapping (QSM).

PubMed

Feng, Xiang; Deistung, Andreas; Dwyer, Michael G; Hagemeier, Jesper; Polak, Paul; Lebenberg, Jessica; Frouin, Frédérique; Zivadinov, Robert; Reichenbach, Jürgen R; Schweser, Ferdinand

2017-06-01

Accurate and robust segmentation of subcortical gray matter (SGM) nuclei is required in many neuroimaging applications. FMRIB's Integrated Registration and Segmentation Tool (FIRST) is one of the most popular software tools for automated subcortical segmentation based on T 1 -weighted (T1w) images. In this work, we demonstrate that FIRST tends to produce inaccurate SGM segmentation results in the case of abnormal brain anatomy, such as present in atrophied brains, due to a poor spatial match of the subcortical structures with the training data in the MNI space as well as due to insufficient contrast of SGM structures on T1w images. Consequently, such deviations from the average brain anatomy may introduce analysis bias in clinical studies, which may not always be obvious and potentially remain unidentified. To improve the segmentation of subcortical nuclei, we propose to use FIRST in combination with a special Hybrid image Contrast (HC) and Non-Linear (nl) registration module (HC-nlFIRST), where the hybrid image contrast is derived from T1w images and magnetic susceptibility maps to create subcortical contrast that is similar to that in the Montreal Neurological Institute (MNI) template. In our approach, a nonlinear registration replaces FIRST's default linear registration, yielding a more accurate alignment of the input data to the MNI template. We evaluated our method on 82 subjects with particularly abnormal brain anatomy, selected from a database of >2000 clinical cases. Qualitative and quantitative analyses revealed that HC-nlFIRST provides improved segmentation compared to the default FIRST method. Copyright © 2017 Elsevier Inc. All rights reserved.

PAM4 silicon photonic microring resonator-based transceiver circuits

NASA Astrophysics Data System (ADS)

Palermo, Samuel; Yu, Kunzhi; Roshan-Zamir, Ashkan; Wang, Binhao; Li, Cheng; Seyedi, M. Ashkan; Fiorentino, Marco; Beausoleil, Raymond

2017-02-01

Increased data rates have motivated the investigation of advanced modulation schemes, such as four-level pulseamplitude modulation (PAM4), in optical interconnect systems in order to enable longer transmission distances and operation with reduced circuit bandwidth relative to non-return-to-zero (NRZ) modulation. Employing this modulation scheme in interconnect architectures based on high-Q silicon photonic microring resonator devices, which occupy small area and allow for inherent wavelength-division multiplexing (WDM), offers a promising solution to address the dramatic increase in datacenter and high-performance computing system I/O bandwidth demands. Two ring modulator device structures are proposed for PAM4 modulation, including a single phase shifter segment device driven with a multi-level PAM4 transmitter and a two-segment device driven by two simple NRZ (MSB/LSB) transmitters. Transmitter circuits which utilize segmented pulsed-cascode high swing output stages are presented for both device structures. Output stage segmentation is utilized in the single-segment device design for PAM4 voltage level control, while in the two-segment design it is used for both independent MSB/LSB voltage levels and impedance control for output eye skew compensation. The 65nm CMOS transmitters supply a 4.4Vppd output swing for 40Gb/s operation when driving depletion-mode microring modulators implemented in a 130nm SOI process, with the single- and two-segment designs achieving 3.04 and 4.38mW/Gb/s, respectively. A PAM4 optical receiver front-end is also described which employs a large input-stage feedback resistor transimpedance amplifier (TIA) cascaded with an adaptively-tuned continuous-time linear equalizer (CTLE) for improved sensitivity. Receiver linearity, critical in PAM4 systems, is achieved with a peak-detector-based automatic gain control (AGC) loop.

Investigation of Mechanisms of Viscoelastic Behavior of Collagen Molecule

PubMed Central

Ghodsi, Hossein; Darvish, Kurosh

2015-01-01

Unique mechanical properties of collagen molecule make it one of the most important and abundant proteins in animals. Many tissues such as connective tissues rely on these properties to function properly. In the past decade, molecular dynamics (MD) simulations have been used extensively to study the mechanical behavior of molecules. For collagen, MD simulations were primarily used to determine its elastic properties. In this study, constant force steered MD simulations were used to perform creep tests on collagen molecule segments. The mechanical behavior of the segments, with lengths of approximately 20 (1X), 38 (2X), 74 (4X), and 290 nm (16X), was characterized using a quasi-linear model to describe the observed viscoelastic responses. To investigate the mechanisms of the viscoelastic behavior, hydrogen bonds (H-bonds) rupture/formation time history of the segments were analyzed and it was shown that the formation growth rate of H-bonds in the system is correlated with the creep growth rate of the segment ( β = 2.41 βH). In addition, a linear relationship between H-bonds formation growth rate and the length of the segment was quantified. Based on these findings, a general viscoelastic model was developed and verified where, using the smallest segment as a building block, the viscoelastic properties of larger segments could be predicted. In addition, the effect of temperature control methods on the mechanical properties were studied, and it was shown that application of Langevin Dynamics had adverse effect on these properties while the Lowe-Anderson method was shown to be more appropriate for this application. This study provides information that is essential for multi-scale modeling of collagen fibrils using a bottom-up approach. PMID:26256473

Investigation of mechanisms of viscoelastic behavior of collagen molecule.

PubMed

Ghodsi, Hossein; Darvish, Kurosh

2015-11-01

Unique mechanical properties of collagen molecule make it one of the most important and abundant proteins in animals. Many tissues such as connective tissues rely on these properties to function properly. In the past decade, molecular dynamics (MD) simulations have been used extensively to study the mechanical behavior of molecules. For collagen, MD simulations were primarily used to determine its elastic properties. In this study, constant force steered MD simulations were used to perform creep tests on collagen molecule segments. The mechanical behavior of the segments, with lengths of approximately 20 (1X), 38 (2X), 74 (4X), and 290 nm (16X), was characterized using a quasi-linear model to describe the observed viscoelastic responses. To investigate the mechanisms of the viscoelastic behavior, hydrogen bonds (H-bonds) rupture/formation time history of the segments were analyzed and it was shown that the formation growth rate of H-bonds in the system is correlated with the creep growth rate of the segment (β=2.41βH). In addition, a linear relationship between H-bonds formation growth rate and the length of the segment was quantified. Based on these findings, a general viscoelastic model was developed and verified here, using the smallest segment as a building block, the viscoelastic properties of larger segments could be predicted. In addition, the effect of temperature control methods on the mechanical properties were studied, and it was shown that application of Langevin Dynamics had adverse effect on these properties while the Lowe-Anderson method was shown to be more appropriate for this application. This study provides information that is essential for multi-scale modeling of collagen fibrils using a bottom-up approach. Copyright © 2015 Elsevier Ltd. All rights reserved.

Can we predict body height from segmental bone length measurements? A study of 3,647 children.

PubMed

Cheng, J C; Leung, S S; Chiu, B S; Tse, P W; Lee, C W; Chan, A K; Xia, G; Leung, A K; Xu, Y Y

1998-01-01

It is well known that significant differences exist in the anthropometric data of different races and ethnic groups. This is a cross-sectional study on segmental bone length based on 3,647 Chinese children of equal sex distribution aged 3-18 years. The measurements included standing height, weight, arm span, foot length, and segmental bone length of the humerus, radius, ulna, and tibia. A normality growth chart of all the measured parameters was constructed. Statistical analysis of the results showed a very high linear correlation of height with arm span, foot length, and segmental bone lengths with a correlation coefficient of 0.96-0.99 for both sexes. No differences were found between the right and left side of all the segmental bone lengths. These Chinese children were found to have a proportional limb segmental length relative to the trunk.

Ion-trajectory analysis for micromotion minimization and the measurement of small forces

NASA Astrophysics Data System (ADS)

Gloger, Timm F.; Kaufmann, Peter; Kaufmann, Delia; Baig, M. Tanveer; Collath, Thomas; Johanning, Michael; Wunderlich, Christof

2015-10-01

For experiments with ions confined in a Paul trap, minimization of micromotion is often essential. In order to diagnose and compensate micromotion we have implemented a method that allows for finding the position of the radio-frequency (rf) null reliably and efficiently, in principle, without any variation of direct current (dc) voltages. We apply a trap modulation technique and focus-scanning imaging to extract three-dimensional ion positions for various rf drive powers and analyze the power dependence of the equilibrium position of the trapped ion. In contrast to commonly used methods, the search algorithm directly makes use of a physical effect as opposed to efficient numerical minimization in a high-dimensional parameter space. Using this method we achieve a compensation of the residual electric field that causes excess micromotion in the radial plane of a linear Paul trap down to 0.09 Vm-1 . Additionally, the precise position determination of a single harmonically trapped ion employed here can also be utilized for the detection of small forces. This is demonstrated by determining light pressure forces with a precision of 135 yN. As the method is based on imaging only, it can be applied to several ions simultaneously and is independent of laser direction and thus well suited to be used with, for example, surface-electrode traps.

A high-resolution 3D ultrasonic system for rapid evaluation of the anterior and posterior segment.

PubMed

Peyman, Gholam A; Ingram, Charles P; Montilla, Leonardo G; Witte, Russell S

2012-01-01

Traditional ultrasound imaging systems for ophthalmology employ slow, mechanical scanning of a single-element ultrasound transducer. The goal was to demonstrate rapid examination of the anterior and posterior segment with a three-dimensional (3D) commercial ultrasound system incorporating high-resolution linear probe arrays. The 3D images of the porcine eye were generated in approximately 10 seconds by scanning one of two commercial linear arrays (25- and 50-MHz). Healthy enucleated pig eyes were compared with those with induced injury or placement of a foreign material (eg, metal). Rapid, volumetric imaging was also demonstrated in one human eye in vivo. The 50-MHz probe provided exquisite volumetric images of the anterior segment at a depth up to 15 mm and axial resolution of 30 μm. The 25-MHz probe provided a larger field of view (lateral X depth: 20 × 30 mm), sufficient for capturing the entire anterior and posterior segments of the pig eye, at a resolution of 60 μm. A 50-MHz scan through the human eyelid illustrated detailed structures of the Meibomian glands, cilia, cornea, and anterior segment back to the posterior capsule. The 3D system with its high-frequency ultrasound arrays, fast data acquisition, and volume rendering capability shows promise for investigating anterior and posterior structures of the eye. Copyright 2012, SLACK Incorporated.

Time and Memory Efficient Online Piecewise Linear Approximation of Sensor Signals.

PubMed

Grützmacher, Florian; Beichler, Benjamin; Hein, Albert; Kirste, Thomas; Haubelt, Christian

2018-05-23

Piecewise linear approximation of sensor signals is a well-known technique in the fields of Data Mining and Activity Recognition. In this context, several algorithms have been developed, some of them with the purpose to be performed on resource constrained microcontroller architectures of wireless sensor nodes. While microcontrollers are usually constrained in computational power and memory resources, all state-of-the-art piecewise linear approximation techniques either need to buffer sensor data or have an execution time depending on the segment’s length. In the paper at hand, we propose a novel piecewise linear approximation algorithm, with a constant computational complexity as well as a constant memory complexity. Our proposed algorithm’s worst-case execution time is one to three orders of magnitude smaller and its average execution time is three to seventy times smaller compared to the state-of-the-art Piecewise Linear Approximation (PLA) algorithms in our experiments. In our evaluations, we show that our algorithm is time and memory efficient without sacrificing the approximation quality compared to other state-of-the-art piecewise linear approximation techniques, while providing a maximum error guarantee per segment, a small parameter space of only one parameter, and a maximum latency of one sample period plus its worst-case execution time.

Hippocampus Segmentation Based on Local Linear Mapping

PubMed Central

Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

2017-01-01

We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively. PMID:28368016

Hippocampus Segmentation Based on Local Linear Mapping.

PubMed

Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

2017-04-03

We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively.

Train repathing in emergencies based on fuzzy linear programming.

PubMed

Meng, Xuelei; Cui, Bingmou

2014-01-01

Train pathing is a typical problem which is to assign the train trips on the sets of rail segments, such as rail tracks and links. This paper focuses on the train pathing problem, determining the paths of the train trips in emergencies. We analyze the influencing factors of train pathing, such as transferring cost, running cost, and social adverse effect cost. With the overall consideration of the segment and station capability constraints, we build the fuzzy linear programming model to solve the train pathing problem. We design the fuzzy membership function to describe the fuzzy coefficients. Furthermore, the contraction-expansion factors are introduced to contract or expand the value ranges of the fuzzy coefficients, coping with the uncertainty of the value range of the fuzzy coefficients. We propose a method based on triangular fuzzy coefficient and transfer the train pathing (fuzzy linear programming model) to a determinate linear model to solve the fuzzy linear programming problem. An emergency is supposed based on the real data of the Beijing-Shanghai Railway. The model in this paper was solved and the computation results prove the availability of the model and efficiency of the algorithm.

Hippocampus Segmentation Based on Local Linear Mapping

NASA Astrophysics Data System (ADS)

Pang, Shumao; Jiang, Jun; Lu, Zhentai; Li, Xueli; Yang, Wei; Huang, Meiyan; Zhang, Yu; Feng, Yanqiu; Huang, Wenhua; Feng, Qianjin

2017-04-01

We propose local linear mapping (LLM), a novel fusion framework for distance field (DF) to perform automatic hippocampus segmentation. A k-means cluster method is propose for constructing magnetic resonance (MR) and DF dictionaries. In LLM, we assume that the MR and DF samples are located on two nonlinear manifolds and the mapping from the MR manifold to the DF manifold is differentiable and locally linear. We combine the MR dictionary using local linear representation to present the test sample, and combine the DF dictionary using the corresponding coefficients derived from local linear representation procedure to predict the DF of the test sample. We then merge the overlapped predicted DF patch to obtain the DF value of each point in the test image via a confidence-based weighted average method. This approach enabled us to estimate the label of the test image according to the predicted DF. The proposed method was evaluated on brain images of 35 subjects obtained from SATA dataset. Results indicate the effectiveness of the proposed method, which yields mean Dice similarity coefficients of 0.8697, 0.8770 and 0.8734 for the left, right and bi-lateral hippocampus, respectively.

29. Photocopy of photograph dated 1930; photographer unknown; original filed ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. Photocopy of photograph dated 1930; photographer unknown; original filed as HE17/p7 in Audio-Visual Collection of Minnesota Historical Society, St. Paul; HANGAR AREA, INTERIOR, SHOWING LONGITUDINAL 'CARRYING' TRUSS AND CANTILEVERED SECTION OF ROOF TRUSSES; LOOKING NORTHWEST FROM SOUTHEAST FRONT CORNER - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Wave Propagation Problems in Certain Elastic Anisotropic Half Spaces.

DTIC Science & Technology

1980-12-01

874-882. 33. Paul , S.L., and Robinson, A.R., "Interaction of Plane Elastic Waves with a Cylindrical Cavity," Technical Documentary Report Mo. RTD...Professor Paul M. Naghdi University of California Department of Mechanical Engineering Berkeley, California 94720 Professor A. J. Durelli Oakland...Burt Paul University of Pennsylvania Towne School of Civil and Mechanical Engineering Philadelphia, Pennsylvania 19104 Professor H. W. Liu Syracuse

16TH Annual Review of Progress in Applied Computational Electromagnetics of the Naval Postgraduate School, Monterey, CA. Volume I

DTIC Science & Technology

2000-03-24

Element Method for Designing Plasma Reactors" Leo Kempel, Paul Rummel, Tim Grotjohn and John Amrhein ............................................ 28...34Finite Element Method for Designing Plasma Reactors" Leo Kempel, Paul Rummel, Tim Grotjohn and John Amrhein...548 "lime-Domain Simulation of Electromagnetic Wave Propagation in a Magnetized Plasma" J. Paul , C. Christopoulos, and

Ontonagon Harbor Operation and Maintenance Activities. Lake Superior.

DTIC Science & Technology

1975-08-01

St. Paul, Minnesota 55101 August 1975 FINAL ENVIRONMENTAL IMPACT STATEMENT OPERATION AND MAINTENAN4CE ACTIVITIES ONTONAGON HARBDOR, MICHIGAN LAKE...SUPERIOR Responsible Office: St. Paul District, Corps of Engineers, 1135 U.S. Post Office and Custom House, St. Paul, Minnesota 55101 Telephone Number 612...Nonesuch shale is a finer siltstone containing recoverable copper deposits. Active mining is present at White Pine, 12 air miles southwest of Ontonagon

Moral Perception and Judgment and a Truly Radical Change of Social Practices: A Reply to Paul Standish's "Registers of the Religious"

ERIC Educational Resources Information Center

Smeyers, Paul

2012-01-01

This article presents the author's response to Paul Standish's "Registers of the Religious". Addressing what he calls the "global", Paul Standish starts from MacIntyre's observation that people live in a world characterized by a vocabulary of value whose purchase on life is no longer authentically experienced: "MacIntyre's diagnosis of the…

38. Photographic copy of historic construction drawing, ink on linen, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. Photographic copy of historic construction drawing, ink on linen, February 1902 (original filed in drawer 98, Bridge Division, Department of Public Works, St. Paul City Annex). Re- flooring and re-paving of Selby Avenue Bridge over tracks of Chicago, Milwaukee & St. Paul RY. CO. - Selby Avenue Bridge, Spanning Short Line Railways track at Selby Avenue between Hamline & Snelling Avenues, Saint Paul, Ramsey County, MN

A case of pediatric live-donor liver transplantation with a left lateral segment reduction by a linear stapler after reperfusion.

PubMed

Zenitani, Masahiro; Ueno, Takehisa; Nara, Keigo; Nakahata, Kengo; Uehara, Shuichiro; Soh, Hideki; Oue, Takaharu; Kondo, Hiroki; Nagano, Hiroaki; Usui, Noriaki

2014-09-01

In pediatric LDLT, graft reduction is sometimes required because of the graft size mismatch. Dividing the portal triad and hepatic veins with a linear stapler is a rapid and safe method of reduction. We herein present a case with a left lateral segment reduction achieved using a linear stapler after reperfusion in pediatric LDLT. The patient was a male who had previously undergone Kasai procedure for biliary atresia. We performed the LDLT with his father's lateral segment. According to the pre-operative volumetry, the GV/SLV ratio was 102.5%. As the patient's PV was narrow, sclerotic and thick, we decided to put an interposition with the IMV graft of the donor between the confluence and the graft PV. The graft PV was anastomosed to the IMV graft. The warm ischemic time was 34 min, and the cold ischemic time was 82 min. The ratio of the graft size to the recipient weight (G/R ratio) was 4.2%. After reperfusion, we found that the graft had poor perfusion and decided to reduce the graft size. We noted good perfusion in the residual area after the lateral edge was clamped with an intestinal clamp. The liver tissue was sufficiently fractured with an intestinal clamp and then was divided with a linear stapler. The final G/R ratio was 3.6%. The total length of the operation was 12 h and 20 min. The amount of blood lost was 430 mL. No surgical complications, including post-operative hemorrhage and bile leakage, were encountered. We believe that using the linear stapler decreased the duration of the operation and was an acceptable technique for reducing the graft after reperfusion. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Analysis of linear measurements on 3D surface models using CBCT data segmentation obtained by automatic standard pre-set thresholds in two segmentation software programs: an in vitro study.

PubMed

Poleti, Marcelo Lupion; Fernandes, Thais Maria Freire; Pagin, Otávio; Moretti, Marcela Rodrigues; Rubira-Bullen, Izabel Regina Fischer

2016-01-01

The aim of this in vitro study was to evaluate the reliability and accuracy of linear measurements on three-dimensional (3D) surface models obtained by standard pre-set thresholds in two segmentation software programs. Ten mandibles with 17 silica markers were scanned for 0.3-mm voxels in the i-CAT Classic (Imaging Sciences International, Hatfield, PA, USA). Twenty linear measurements were carried out by two observers two times on the 3D surface models: the Dolphin Imaging 11.5 (Dolphin Imaging & Management Solutions, Chatsworth, CA, USA), using two filters(Translucent and Solid-1), and in the InVesalius 3.0.0 (Centre for Information Technology Renato Archer, Campinas, SP, Brazil). The physical measurements were made by another observer two times using a digital caliper on the dry mandibles. Excellent intra- and inter-observer reliability for the markers, physical measurements, and 3D surface models were found (intra-class correlation coefficient (ICC) and Pearson's r ≥ 0.91). The linear measurements on 3D surface models by Dolphin and InVesalius software programs were accurate (Dolphin Solid-1 > InVesalius > Dolphin Translucent). The highest absolute and percentage errors were obtained for the variable R1-R1 (1.37 mm) and MF-AC (2.53 %) in the Dolphin Translucent and InVesalius software, respectively. Linear measurements on 3D surface models obtained by standard pre-set thresholds in the Dolphin and InVesalius software programs are reliable and accurate compared with physical measurements. Studies that evaluate the reliability and accuracy of the 3D models are necessary to ensure error predictability and to establish diagnosis, treatment plan, and prognosis in a more realistic way.

Automated liver segmentation using a normalized probabilistic atlas

NASA Astrophysics Data System (ADS)

Linguraru, Marius George; Li, Zhixi; Shah, Furhawn; Chin, See; Summers, Ronald M.

2009-02-01

Probabilistic atlases of anatomical organs, especially the brain and the heart, have become popular in medical image analysis. We propose the construction of probabilistic atlases which retain structural variability by using a size-preserving modified affine registration. The organ positions are modeled in the physical space by normalizing the physical organ locations to an anatomical landmark. In this paper, a liver probabilistic atlas is constructed and exploited to automatically segment liver volumes from abdominal CT data. The atlas is aligned with the patient data through a succession of affine and non-linear registrations. The overlap and correlation with manual segmentations are 0.91 (0.93 DICE coefficient) and 0.99 respectively. Little work has taken place on the integration of volumetric measures of liver abnormality to clinical evaluations, which rely on linear estimates of liver height. Our application measures the liver height at the mid-hepatic line (0.94 correlation with manual measurements) and indicates that its combination with volumetric estimates could assist the development of a noninvasive tool to assess hepatomegaly.

Houston, We Have a Podcast. Episode 41 The Space Launch System Part.1

NASA Image and Video Library

2018-04-20

Production Transcript for Ep41 The Space Launch System Part.1.mp3 Gary Jordan (Host): Houston, we have a podcast. Welcome to the official podcast of the NASA Johnson Space Center Episode 41, the Space Launch System part one. I'm Gary Jordan, and I'll be your host today. On this podcast, we bring in the experts, NASA scientists, engineers, astronauts, all to let you know the coolest information right here at NASA. So, today, we're talking about the most powerful rocket since the Saturn V moon rocket. It's called NASA's Space Launch System. So, we've got two guests from Marshall Space Flight Center in Huntsville, Alabama here with us today to tell us a little bit about the rocket, the payloads it will carry. Don't worry. We'll define what a payload is. And then, where it's going to go. Spoiler alert, it will bring people big stuff and little stuff all farther than we've ever gone before. Wait. Why did I do that? That totally ruins the, oh wait. Never mind. It doesn't ruin anything. This is a really good topic, jam packed with information. So much information that we're going to do this in two parts. This is part one. So, with us today are David Smith and Paul Bookout. David is the Vice President for Advanced Programs at Victory Solutions in Huntsville, Alabama. He has a long career in aerospace engineering and is a Subject Matter Expert on rocket architecture and how payloads fit inside the rocket. He wrote the SLS mission planner's guide which gives payload developers a general idea of the capabilities of the rocket and some technical specifications, so they can determine how their payloads might fit inside of it. He looks after some of the big payloads. Our other guest is Dr. Paul Bookout, EM-1 Secondary Payloads Integration Manager who manages integration of five CubeSats in the giant rocket as well as the avionics that will control deployment of the 13 small satellite payloads on the first mission of SLS and Orion called Exploration Mission-1, EM-1. He spends his time managing the little payloads, not much bigger than a shoebox, that goes inside of a skyscraper-sized rocket. So, we're going to be talking about just how powerful this monster rocket is, its unique capabilities, and what it will be used for, where it is in its development, its first mission with the Orion crew vehicle, and then look ahead to the future to missions to the moon, to Mars, and throughout the solar system. So, we are go for launch with Mr. David Smith and Dr. Paul Bookout for the Space Launch System Program. T minus five, four, three, two, one, zero, and liftoff of Episode 41 of Houston, We Have a Podcast. Always wanted to do that. Feel like I just ruined it. You know what? Let's just start. [ Music ] Host: T minus five second and counting. Mark. [ Music ] Host: There she goes. Host: Houston, we have a podcast. [ Music ] Host: All right. Paul and David, thanks so much for coming on the podcast today. We talked about Orion on a few episodes so far but really haven't had the privilege to talk about he giant rocket that Orion is going to be on, the SLS. And, we have you guys here from Marshall to actually talk to us about this rocket. So, thank you very much for coming on. David Smith: Sure. David Smith: Thank you for having us. Host: Our pleasure. Host: All right. Just to sort of back up, we have Paul Bookout and David Smith, so you guys want to talk a little bit about each one, so we can identify your voices. Paul Bookout: David, go ahead. David Smith: Well, sure. I'm just an engineer. My associate Dr. Bookout is a doctor. Host: Okay. David Smith: But, we both work together on trying to find innovative ways to associate payloads with the capability of SLS which is going to be the world's largest rocket. So, I kind of look at the larger payloads, and Dr. Bookout looks at maybe some of the other kind, smaller payloads that can fit in the niches that are left over. Paul Bookout: Well, thank you Vice President David. David Smith: Yes. Paul Bookout: I appreciate you talking about introducing myself. So, what we have is secondary payloads. Again, we're just trying to understand the whole utilization of SLS since it's going to be the most powerful rocket built since the Saturn V. It's going to have a lot more capability, so we want to utilize it to its fullest. Host: Okay. So, you said there's going to be, basically, we're going to utilize the rocket to its maximum potential. We got this big rocket, and we're going to test it. But, while we test it, let's put some cool stuff on it. Paul Bookout: Exactly. Host: So, let's back up and talk about just SLS. What is SLS? What is this giant rocket that we're talking about? Paul Bookout: SLS is America's rocket. It's the next NASA's launch vehicle that's going to be able to put humans back to the moon and further out into deep space. Of course, a lot of it's built on shuttle hardware heritage. The SLS rocket's made up of the solar rocket boosters, a main core, an upper stage, and then the crew Orion spacecraft with a co-manifest payload or a primary payload. And, David will talk a little bit more about that later. So, of course, this is NASA's first exploration class launch vehicle since Saturn V, so we're going to be putting humans back to the moon, out to deep space, and eventually, you know, to Mars systems. It has a very large mass lift capability and also volume, so some of these larger probes that are satellites or probes that are going to outer planets that they'll be able to arrive at their destination in just a few years instead of maybe eight to ten years. [00:05:24] You're cutting that trip down to one or two years. So, it's a lot of savings there. Host: So, that's a really important part to kind of hone in on is just the versatility of this rocket. You're talking about a giant rocket that can take people, giant payloads, faster, farther. That's pretty much the whole summary of the SLS, right? Paul Bookout: Yes. Definitely. Host: So, what's, what does it take to be human rated? So, I guess the difference between something that's not a rocket and something that is. Paul Bookout: Of course, it goes through the whole development process, starts at the beginning. You have to have safety emission assurances involved from the very beginning. Just an overview, you have to have, like redundant systems. If something goes wrong with one system, there's another system to kick in to back up to still make the vehicle safe. There's safety reviews throughout the whole process. We do additional testing, a lot more testing than other commercial launch vehicles do just to make sure that the vehicle is safe for humans. Host: That's really the main thing, right? Paul Bookout: Yeah. [00:06:33] Host: The safety. But, then, also the redundancy because I guess redundancy is cost. Redundancy is weight. So, you have to factor that into a rocket where you can just say, "Oh, if it fails, you know, with the primary systems, it fails." But, at least the only thing we lose is this piece of hardware. And, not to say that that's not a bad thing, but. Paul Bookout: Right. Host: It's very different from human life. So, I guess, absolutely, you need to be considerate of that. Paul Bookout: Right. And, there is a tradeoff, as you was saying. Additional systems, more mass, and that's mass that is being taken away from your primary payloads. Host: Yeah. Paul Bookout: And lift capability, but we need that to be safe. Host: You know what? I actually always wanted to ask this question, but you said primary payloads. I get this question all the time from folks not in NASA, and it's just, we use this term all the time, but what, to you, is a payload? [00:07:22] Paul Bookout: A payload is anything that goes up on top of the rocket that's lifted into space. It can be a satellite. I can be probes. Of course, the Orion spacecraft, once it's on the rocket, it can have its own second co-manifested payload along with it. So, just anything, really, that's launched into space. Host: Does a person count as a payload. Paul Bookout: We don't like to refer to. [ Laughter ] Host: It doesn't humanize it as much, right? Paul Bookout: No, it doesn't. No. Host: So, I guess, for example, going back to that co-manifest thing, the Orion. The Orion would be the payload. That would be the primary thing that you want to bring into orbit. Paul Bookout: Correct. Host: But, then, there's something that is, something called co-manifested which means it's not the primary thing, but it's also part of the part that you want to lift the mission. Paul Bookout: Correct. Host: Okay. Paul Bookout: For example, on the second generation of the SLS rocket, it will have capability of launching a co-manifest payload along with Orion, and it could be anywhere from additional probe going out into the moon, or it can be call separation bus, propulsion system that's launched. And, then, when a habitat is launched, then they can be combined and go to the moon. So, it's, allows us to build capabilities out in space, too, with co-manifested payloads. Host: Okay. Paul Bookout: Along with Orion. Host: Is that one of the things you're working on? Or, you're working on, I guess, secondary payload? Paul Bookout: Yes. I'm mainly focused in on secondary payloads. Host: So, what's secondary payloads? Paul Bookout: Okay. Secondary payloads, or they call auxiliary payloads. Host: Okay. Paul Bookout: They're payloads that do not drive the primary mission of the, of that launch. For example, on EM-1, we have secondary payloads on that. That's EM-1, Exploration Mission-1. Host: Okay. Paul Bookout: First launch of SLS rocket. David Smith: Yeah. Paul Bookout: We have 13 payloads on that, and I'll talk a little bit more about that later. But, the primary requirements they have is for secondary payloads in general is do no harm to the vehicle and minimal impact. So, the do no harm aspect is that we have to fly safe. The whole system, deployment system and everything, is designed to be safe. Like, all the CubeSats are turned off during launch. They have to have, like, redundant systems, as in two separation switches that allow them to turn on. Because, if one fails while we're being launched, it could turn on the systems. So, we have two there. Host: Oh, okay. Paul Bookout: To back that up, to keep it safe. And then, minimal requirements, of course, if the rocket is ready to launch and the secondary payload's not ready yet, it's going to launch. Because it does not affect the primary mission of the payload, of the launch. Host: Right. Paul Bookout: Of that. Host: Well, that puts a lot of constraints on you, then, huh? Paul Bookout: Yes, yes it does. Host: Because, not only do you have to worry about these, and I guess we can kind of hone in on the CubeSats a little bit later. But, you have to worry about the CubeSats, but now you have to add something else to it. Now, you have to add these redundant systems. And then, there's no guarantee that if you're not ready, that's okay. We're going to go without you. Paul Bookout: Right. Exactly. SLS is, the first rocket's not going to be the only configuration of SLS. And, of course, SLS is Space Launch System. We, the first launch is going to be called Block 1. Then, we're going to be stepping up to Block 1B which means we're going to be adding a different upper stage. Right now, we're utilizing an existing Boeing ULA upper stage to use on this mission, mainly to save initial money so we can develop the core stage. And, once the core stage has been developed, then we can have additional funds to start developing the new upper stage or exploration upper stage. Host: Okay. Paul Bookout: Okay? And, that's going to be the Block 1B configuration. And, Block 1B will have actually two configurations. It'll be a crew which was, as we talked about before, the Orion spacecraft with a co-manifested payload. The other configuration will be the Block 1B cargo where that would be your primary payloads. So, the only payload will be that major payload. Host: Okay. So, when you say "Block", you're looking at the entire rocket configuration. Paul Bookout: Correct. Host: And, Block 1 is this configuration with the ULE booster, right? Paul Bookout: Right. Host: Okay. And then, Block 1B has the NASA booster on top. Paul Bookout: Correct. Host: Instead of the ULA, but then you can do crew or cargo on that one. Paul Bookout: Exactly. Host: Whereas, EM-1 you don't, and EM-1, we can get into this later, is, you're not going to have crew on it, right? That's not part of the test. That's for one of the later missions. Paul Bookout: Correct. Host: I see. So, really, the blocks are kind of the stages of developing the rocket into its full capability of. Paul Bookout: Right. Host: Of this eventual Mars lander. That's awesome. So, now, you're using these commercial elements. You're using ULA in Block 1 and the leftover solid rocket boosters until, eventually, 1B, 1B crew, you get to Block 2. Now, you have the configuration. New boosters. You got the NASA upper stage. You got all of these configurations, and now you can go to, where can you go? David Smith: Well. Host: Is it just to Mars? David Smith: Well, you really need Block 2, ultimately, to fulfill a human settlement on the lunar surface as well. Host: Really? David Smith: You need a kind of lift capability. But, if you want to assemble an architecture, because it'll take multiple flights of a Block 2 to assemble a human architecture capable of transiting to Mars, you'll need four to five Block 2 flights at a time to assemble that stack that can go to Mars. Host: So, what's, I guess, how much more power does Block 2 provide you that, I guess, Block 1B would not? David Smith: Well, it nominally, you're talking another 25 tons or so. So, it could bring a second Orion vehicle in comparison because Orion weighs about 25 tons. So, it, really, from a lift standpoint, is maybe a fifth more powerful than the Block 1B, and it gives you that extra diameter, potentially for the payload ferrying that would allow, you know, the smaller the diameter of the ferrying, the taller a lander needs to be. And, think about a lander on the surface of the moon or Mars, if it's three or four stories, that's a lot of vertical height an astronaut has to overcome every time they're taking stuff back and forth. Host: That's right. David Smith: So, we're, the larger the diameter, the shorter can be the squatter, can be the easier it is to manipulate items on and off a lander. Whether it's on the moon or Mars. Host: Okay. Wow. So, then, you're talking about once this Block 2 configuration is done with the new solid rocket boosters, you can actually have a wider payload go on top of the rocket. David Smith: Right. Well, there's a nuclear thermal propulsion that's out there that has the potential of getting people to Mars a lot sooner. It needs a much larger diameter because it used hydrogen as a fuel. Hydrogen is very bulky because it isn't very dense. And so, if we were ever to use a new kind of propulsion that would lower the time to get to Mars, you need a Block 2 vehicle. A smaller rocket will never allow you to do nuclear thermal propulsion. Host: Okay. Let's go back to some of these other configurations. I kind of want to get a sense of the look and feel of this rocket. We sort of talked about it, but to just sort of go into detail. If I was looking at let's just say the Block 1 configuration, the one that's actually going to go for EM-1, what does that look like? How tall is it? What's the weight of it? How much power? David Smith: Right. So, roughly Block 1 and 1B are somewhat similar. Host: Okay. David Smith: They're going to be about the same height as the Saturn V. Host: Oh. David Smith: Which means it's a big rocket, but part of that's because we can't really exceed the vehicle assembly building limitations that are at the Cape. So, you want to make it as big as you can, so you can put as much fuel in it as you can. Basically, the thrust of the Block 1 vehicle which is similar to the Block 1B for the solid rocket motors is about 3.6 million pounds each. Those only fly for about two minutes. Then, you have the core engines. There's four space shuttle era type SSMEs that each have about 512,000 pounds of thrust. You multiply that by four. They operate for about eight minutes. Together, you get about a total thrust of about 8.8 million pounds which gives you an escape velocity of over 22,000 miles an hour. The core stage itself is about 2/3 the length of a football field which is pretty tremendous. One single stage of this vehicle's about 2/3 of a football stadium. And, which is around 212 feet, and the Block 1B ferrying that we talked about, the 8.4-meter diameter ferrying, could accommodate up to three school buses inside its volume. So, that's pretty incredible when you think about the size of what can be lofted in a single vehicle like that. In comparison, the Block 1 vehicle, you know, can throw 70 tons to lower earth orbit where the shuttle can only do 28 tons to low earth orbit. So, it's about three times more powerful than the shuttle. Host: Wow. So, you're talking, you're comparing it to the Saturn V in terms of its size but talking about these efficient engines. What makes, what is it about the engines that's more efficient that's giving you this extra power? David Smith: Well, they, you know, the shuttle engines were rated at 100% thrust originally, and I think they got them up to 109%. So, they actually got them to work 9% more efficiently at the end of the shuttle program. We're taking these up to 11% more thrust, and maybe even 13% more thrust. So, you're really pushing these engines to their limit, and the, it's really coupling their efficiency now at 113% thrust with the reliability of the shuttle system. Host: Unbelievable. The engine itself is called an RS25, right? Paul Bookout: Yes. Host: That's what it's called. And, these are the engines that were on the shuttle. Now, you're pretty much just putting it on the SLS, but it sounds like there's a good reason for that. It's because you've flown the shuttle so many times, improved the capability of it past its, like, total 100% thrust ratio. Now, you're going, you're going past the 100%. So, basically, is like why would we, why would we do something else? We worked so hard on this one. This one is, like, extremely efficient. Why would we, and we can make it even more efficient. That's the logic behind it? Paul Bookout: Well, right. Initially, of course, we have about, I believe, 16 space shuttle main engines or these RS25s left over from the shuttle program. So, we're utilizing the existing hardware to save cost while we're developing the core stage. You know, the first part of the SLS. Host: Yeah. Paul Bookout: And, as you mentioned, we are updating the engines, getting more capability out of them. So, to that point, we can do four per, so we can do about four launches, four rocket, or four engines on each launch. So, we can do about four launches with the current RS25s. Host: Okay. And, that, is that for one of the later configurations? Paul Bookout: That's correct. Host: Okay. Paul Bookout: Yeah. Host: Is it the Block 2? Paul Bookout: The Block 2. Host: Block 2? Paul Bookout: Block 2 and beyond. Host: Oh, okay. I see. I see where the whole idea of staging this whole thing comes from, right? Paul Bookout: Correct. Host: You've got, you're using the leftover solid rocket boosters, and you're using this commercial upper stage. And, it's just basically getting to this point where you're going to maximize the efficiency of the rocket. Paul Bookout: Right. Host: Unbelievable. So, three school buses inside of the 1B configuration, right? That's, is it about the weight of three school buses? Is like taking three school buses to space? David Smith: No, it would be, it would be more than that. Host: More than that? David Smith: I mean, nominally, if you went to the moon, we're going to take, the Block 1B could take roughly 40 tons to lunar vicinity which is, which is pretty incredible. Host: Wow, and just in terms of not only, like, quantity, you're talking three school buses. But, also size. David Smith: Yeah, and mass. Host: Also weight. David Smith: Right. Host: You know, you got all of these, all these different components. So, I guess we can kind of focus in on now that we kind of understand the rocket and the evolution of the rocket, let's go to that first, that first test flight, EM-1. We've talked about EM-1 on the podcast before, especially from testing Orion and that. But, really haven't focused in on what is it about, what is it about EM-1 that we're testing SLS for? So, let's start with that. What are we going to test, and I guess we can kind of start with the overview of EM-1 for those who haven't listened to it before. Paul Bookout: Right. So, EM-1 is, of course, going to be the first launch of the SLS rocket. Its primary segments are, of course, solid rocket motors which are a heritage from shuttle hardware. Shuttle had four segments, where EM-1 is going to have five segment motors. Then, of course, the core stage which is heritage off the shuttle external tank but made longer for additional capability of fuel. And, we're also using the main engines from the shuttle program with updated technology and ratings to get more power out of those four rockets on there. So, that makes up the primary lift capability of the SLS rocket. On top of that, we have an interim cryogenic propulsion stage, which, or second stage, upper stage, that we're utilizing from Boeing, existing hardware for EM-1 mission. And then, of course, in addition to adaptors, then there will be the Orion spacecraft, which is the primary mission of EM-1 is to test out the SLS rocket. Then, also, to test out the Orion spacecraft with its trajectory and telemetries and communications. It's going to be on about a 25 1/2 day mission to distant retrograde orbit. That really means just go way past the moon and come back. Host: Yeah. Paul Bookout: You know, a 25 1/2 day trip. Of course, and, you know, we're doing all this because, again, for the safety aspects. We want to test the vehicle out and Orion spacecraft before we put humans in it. Host: Right. Paul Bookout: So, we want to make sure it's safe, make sure everything works. And, that's that safety aspect, that human rated part of a launch vehicle. Host: So, the human rated part is the Orion can go to 25.5 days, or is this going past what it's expected to possibly operate at? David Smith: I think that's a nominal timeframe for the Orion with crew. So, this is pretty much, I think, its extreme capability. Host: Yeah. David Smith: But, you know, part of it is testing just the systems period. You always, for human rating, you always want to test it far in, you know, far from what the humans will actually experience so that you have a safety factor that's sufficient for human use. Host: Oh, yeah. Because if you're going to be operating on, say, 16 day missions, you don't really want to, okay. Well, let's just test 16. Paul Bookout: Exactly. Host: You really want to go kind of further out and see, all right. Let's see how far this puppy can go. David Smith: And, I think part of this mission's objective is to bring it in at a lunar return velocity to test that heat shield. Host: Yeah. David Smith: You can't do it from low earth orbit. You got to kind of go out and bring it in fast, so. Host: So, what's the difference with EFT-1? That was one of the first test flights we did where we didn't go all the way out to the moon, but we did kind of a, this large apogee so that we can get up to, I think it was some, like 25,000 miles. Or, maybe it was a little slower than that. The difference is between EFT-1 and EM-1. David Smith: I think, I think it was very close to what they would experience in a lunar return, but it's not the actual lunar return. Host: I see. David Smith: Right, so you want to be able to stage it. You want to go out in orbit. You want to test the time that you're out in orbit. That was a very short mission, maybe five or six hours. Now, we're talking 25 days. Well, all the equipment still work when it's, you know, soaked in a cold temperature, hot temperature, all those days. And, now, you're coming in. Will it all work when it comes to the right moment. So, this really puts the pedal to the metal. Host: That's right. So, what is it? I guess the relationship between what are you guys looking at for SLS versus Orion on this particular mission, EM-1? Paul Bookout: So, for SLS, again, we want to test all the systems, make sure they're fully functional. We'll be checking out redundant systems indirectly, of course. And, communications with the vehicle, since it's the first time the vehicle's being launched. We're all, we're talking with the vehicle all the way up. Host: Yeah. Paul Bookout: So, we want to make sure all those ground systems are ready to support, actually, human flight mission. So, it's just not the vehicle. It's the overall architecture of everything that goes into supporting a launch that we want to verify and check out. Host: Oh, that's right. Now, we're preparing to go into fly deep space missions. So, not only is it, all right, let's test the hardware, but let's test to operational aspect. Paul Bookout: Exactly. Host: Let's test what it's going to take to actually do these missions from the broadest perspective possible. David Smith: And, that includes, even, just bringing the, you know, the pieces are being built all over the place. Host: Yeah. David Smith: And, tested all over the place. So, just bringing them together at the cape and making sure they can be integrated in a safe and timely fashion for launch. That, in itself, is a really important objective. We're talking about such a large rocket. Paul Bookout: Yeah, so this is the first time all those components going to be coming together, and there's going to be hiccups along the way. And, we just need to understand how this vehicle goes together and make sure we do it correctly. Host: So, you say the vehicle's going to be talking to you guys throughout its flight. What is it going to be telling you? What kinds of data are you really looking for that's really going to tell you that this thing is working how we're expecting it to work? David Smith: Well, remember, you're talking to payload guys, so, you know, we're more interested in seeing what the payload's going to experience. Host: Yeah. David Smith: But, think about this. When it launches on the pad, it has an incredible noise issue coming off that mobile launch platform. That's why, if you remember, they had these things called rainbirds, the big sprinklers that start spraying as soon as the engines go to try to mitigate that noise. Host: Right. David Smith: The payload is particularly sensitive to it. Obviously, the vehicle itself is sensitive to that noise as well. So, acoustic mitigation is one of the most important things at launch. Then, we have a thermal issue, right? We go up to max Q, max dynamic pressure. We have a certain heating that is, occurs on the outside of the vehicle. And, before, we got to get through all that heating before we can make sure that the crew is going to be safe, that we can take the shielding off the Orion and so forth. So, we're going to be testing all those environmental concerns as we go forward, and of course, the jettisoning of, you know, the SRBs off the core stage. Then, the ICPS in Orion off the core stage. And then, of course, then, the Orion off the ICPS. All these jettison events, and there's quite a few of them, are extremely important, and we need to test those. Each one has its associated thermal and acoustic issues. So, we're going to test each one of those as it goes forward. Paul Bookout: Since this is the first launch of SLS rocket, we don't really understand the full environments that it's going to be launched in. As David mentioned, the thermal, interior thermal, acoustic, vibration. It's the first time we're going to launch it. So, what we're also have is a lot of instrumentation on this vehicle to be able to measure the actual vibration levels and everything else. So, we can, once we go back to designing and looking at what we call safety factors, reducing those so we can have more margin on the vehicle and means that goes into more mass lift capabilities. So, we're trying to understand the overall characteristics of the vehicle itself. So, in addition, for secondary payload, or payloads in general, we can give them more of an accurate environment that they will see during launch. As in, how much vibration they'll feel, how much thermal environments that they'll see. So, when they start designing their payloads for, to run the ride on this vehicle, they can have more of an accurate environment. And, maybe not have, make it a lot more efficient design. Host: Okay. So, then, what data are you going off of now based on, you guess you haven't launched the SLS. So, what are you assuming, or where are you getting the data from? David Smith: We have, we started off with assuming, at least for the payloads, that we would provide an ELV, and expendable launch vehicle class environment. Host: Okay. David Smith: So, if you've flown on Atlas or Delta, you should expect nothing worse than that. Host: Okay. David Smith: That's our starting point. Host: Oh, okay. David Smith: Now, what Paul's going into is we're going to try to characterize is that really true? So, the first flight's important. Are we in? Are we out? What do we have to do? Is there more foam that you got to put in the payload section to mitigate the noise? That's what we're trying to figure out. But, we should be within an ELV class is what we're projecting right now. Host: Okay. So, then, I'm assuming you're going to have some actual science on board EM-1, right? Because you're testing, you're testing the structure of EM-1. You're testing the rocket. But then, you have this mission. Why not take advantage of it? Is there anything else going on the EM-1? Paul Bookout: Oh, definitely. Host: Okay, good. Paul Bookout: Yes. We have, we'll have 13 secondary payloads that we're going to be launching on EM-1. Host: Wow. Paul Bookout: That'll, that is located in the Orion stage adapter. That's the segment that connects the SLS rocket to the Orion spacecraft. So, it's a small ring about five feet high. About 18 or so feet in diameter. And, along the inner circumference of that is where we are mounting these 13 secondary payloads. Host: Oh, so I guess they have to be kind of small, right? That's not a lot of space compared to the, what's in the ferrying. Paul Bookout: Correct. So, on EM-1, we have 13 CubeSats. CubeSats are defined as a, we call a 1U, which is about ten by ten by ten-centimeter cube. Host: Okay. Paul Bookout: So, what we're having on EM-1 is allowing them to go up to what we call a 6U. So, it's a CubeSat that's about the, a little bit larger than the size of a shoebox, a large shoebox. Host: Okay. Paul Bookout: And, that's kind of the dimensions of these 6U CubeSats that we're having on EM-1. David Smith: Which is the most common CubeSat, really, today, right? Paul Bookout: Correct. Exactly. So, we have multiple missions that these payloads are going to be doing. So, we've got one destination is to the moon. We have Lunar Flashlight which is out of Jet Propulsion Laboratory, and their primary mission is to search for ice deposits and resources on the moon using a laser. Host: Ooh. Paul Bookout: Okay. And, the second one is Lunar IceCube which is Morehead State University up in Kentucky. And, they're going to also be searching for water of all forms and volatiles on the moon using infrared spectrometer. These are some big words that I can't even define, so. [ Laughter ] LunaH-Map is from Arizona State University, and they're going to be creating high fidelity map of near surface hydrogen in craters on the moon. Lunar IR is from Lockheed Martin in Colorado, and they're going to be performing advanced infrared imagery of lunar surface. We've got one that's going to the sun facility, and it's called CuSP. It's from Southwest Research Institute here in Texas, and it's going to be measuring particles and magnetic fields of space weather between us and the sun. We have one that's going around the Earth. It's called EQUULEUS. It's a Japanese payload, and we actually have three international payloads on this mission. And, I'll touch on those others. Host: Awesome. Paul Bookout: So, again, EQUULEUS is from JAXA. It's the University of Tokyo supporting that. I mean, it's imaging the Earth's plasma sphere for a better understanding of Earth radiation environment. And also, it's going to be initially on the far side of the moon and detecting any meteor crater flashes that may impact the far side of the moon. Host: Wow. Paul Bookout: So, they'll be out there for about two months or so and just hopefully they'll be able to catch something. Some of the other missions are BioSentinel. It's from Ames Research Center, and they're going to be using baker's yeast to see the effects of radiation on actual live items, you know, live yeast. And, then, ArgoMoon, which is the European Space Agency, is built in Italy. It's going to be observing the interim cryogenic propulsion stage. That's upper stage is going to be deployed. Look at that upper stage, and then it's going to go on some additional missions. And, it's going to look at the upper stage to see what kind of effects the environment has during liftoff on the upper stage. Because, until now, we, once the upper stage is launched, we usually don't get a chance to look the conditions of that. This will give us some feedback and see what the upper stage has went through, if there's any damage or anything. Host: It sounds like these CubeSats are all over the place. Paul Bookout: Yes. Yeah. I've got a couple more here. Host: Oh, really. Paul Bookout: I haven't got to my two favorite yet. So. Host: Oh, we're standing by. Paul Bookout: Okay. Centennial Challenge. That was a challenge that NASA set up called Cube Quest, and it's to help develop communications for these smaller CubeSats. There's two challenges. One was a lunar challenge to around the lunar surface and for longevity. And, the other one was a deep space mission which was a CubeSat, as it says, going out into deep space to see how far and long and what burst rates and clarity that you can have in your signals. So, there's total prizes for everything through all the development and final missions. It's up to $5 million. Host: Wow. Paul Bookout: So, that's a lot of money. Host: Yeah. Paul Bookout: Spread out over those. So, you did, you asked what my two favorite payloads are. Host: Oh, yeah. Paul Bookout: Let me tell you. One of them is NEA Scout. That's developed at Marshall Spaceflight Center. What's unique about that is NEA Scout means Near Earth Asteroid. So, they're going to be going to a near earth asteroid. But, the exciting thing about it is that they're going to be using solar cell to get there for their propulsion system. So, this is the first time a solar cell will be used to, for propulsion out into deep space. There have been other missions in low earth orbit to check out the technology and feasibility of solar cells, but this is the first time going out to deep space. And, for a CubeSat that's a little bit larger than a shoebox, it will be deploying the cell that will be 40 by 40 feet. Host: Whoa. Paul Bookout: So, that's huge. Host: Wait, and a little CubeSat. Paul Bookout: In a little CubeSat. Host: And, it deploys a 40 foot. Paul Bookout: Yes. Host: Oh, wow. Paul Bookout: Yeah, so that solar cell is very thin material. Host: Yeah. It must be to fold up into, like, this ten-centimeter cube thing. Paul Bookout: Exactly. Host: So, so, the solar. Paul Bookout: You said ten centimeters. 6U CubeSat is 10 by 20 by 30. Host: Oh, because this is 6U. Paul Bookout: 6U, correct. Host: Oh, okay. Okay. Okay. So, solar sails, though, this is, it basically unfurls this 40-foot sail, and is it the one where the high-power laser that pushes it? Paul Bookout: No. Paul Bookout: That's different. Paul Bookout: This is going to ride the solar winds. Paul Bookout: Ride the solar winds. Paul Bookout: Solar particles will be pushing it along. It'll do actually a fly by the near-earth asteroid as it comes up. It'll be taking images all the way around as it passes. Host: Okay. Wow. Paul Bookout: So, and my ultimate favorite one is. Host: Yeah, we didn't get the last one. Paul Bookout: Is actually the one that I'm the Secondary Payload Integration Manager for. Host: Oh. Paul Bookout: So, it's one of my CubeSats. Host: So, it's an unbiased favorite, then. Paul Bookout: Yes. Host: Okay. Paul Bookout: Yeah, still. It's called OMOTENASHI. It's another Japanese CubeSat. Host: Okay. Paul Bookout: And, their mission is to land on the moon. Host: Oh. Paul Bookout: Can you imagine a small little CubeSat, you know, a little bit larger than a shoebox, land on the moon? Of course, and the big thing about it is that they're going to be using a solid rocket motor to slow down to be able to land on the moon. So, that's one of the things on EM-1 that we're offering that previous commercial launch vehicles and that don't offer propulsion systems for secondary payload to be able to utilize that. That's one thing EM-1 and SLS is allowing. So, that's a huge deal. Host: Yeah. Paul Bookout: For those. So, if OMOTENASHI is successful at landing on the moon, they'll be the fourth nation in the world to have actually land and do some science on the moon. Host: Wow. Paul Bookout: You know. Host: So, what kind of science? Paul Bookout: Well, because, again, they're still a small payload, so they can't get large science instruments to the moon, when they land, actually land on the moon, all that will be left is about the size of a sandwich box. Because they have to get rid of all the extra weight to be able to slow down enough to be able to land. And, they'll probably so some soil impact measurements, as in how soft vibration, shock, as it's landing on the moon. And, I, so, and they're only going to be able to do it for about 30 minutes or so. Again, because of the size, what we're limiting them to. Host: Yeah. Paul Bookout: They can't get the mechanics, orbital mechanics and velocities and everything. I'm sorry. Host: So, it's, it's kind of general on where you can land, then? It's just like, it's just going to land. It's not going to land in a targeted spot, I guess? Paul Bookout: Correct. They know the general vicinity where it's going to land. Host: Okay. Paul Bookout: But, they can't have ultimate control, like any of the other landers that have larger systems, propulsion systems, to slow them down. So, they would be actually, once the solar motor fires, they'll still be traveling at about 60 miles an hour when they impact the moon. So, they're going to inflate these impact balloons to actually bounce, similar to what they've done on Mars, some of the Mars Rovers. Host: Okay. Paul Bookout: So, it'll come and impact moon and bounce and then finally rest on the moon. Host: Okay. Paul Bookout: And, do about 30 minutes of impact soil measurements. Host: Wow. How would that be, though? I'm imagining, I mean, landing at 60 miles an hour. That's, you know. Paul Bookout: Well. Host: That's not slow, but at the same time, it's the moon, right? It's. Paul Bookout: Right. Yes, but then again, you're not going directly into it. You know, you're coming in at an angle, too. Host: At an angle. Paul Bookout: So, it's not a fully impact. Host: Okay. Great. Paul Bookout: Direct impact, so. Host: So, you got all these CubeSats going around the Earth, around the upper stage, around the moon, on the moon, to deep space. Where do you deploy, how does that work? Where do you deploy everything? It's not just like you just let everything go at all. It has to be pretty controlled because each one has a very specific mission. Paul Bookout: Right. We've created what we call bus stops. Host: Oh. Paul Bookout: They're basically different aspects of the trajectory of the upper stage. So, the first bus stop is when you're in between the two radiation belts or Van Allen belts. Bus stop two is when you've passed all the radiation belts. Bus stop three is half way between the Earth and the moon. Bus stop four is the closest proximity to the moon, and bus stop five is when you're going into a heliosynchronous or sun orbit. And, that's where the upper stage will be disposed into the sun orbit. So, when a payload says, "Hey, I want to get off at 200,000 miles away from the Earth." Well, okay, where is that exactly? So, that's why we kind of created these bus stops. Host: I see. Paul Bookout: They can get off anywhere they want to, but it helps us relate to the areas where they want off. So, most of them are wanting off at stop one. About seven or eight of them. Because they need to get out and start changing their trajectory as soon as possible. Again, we're offering propulsion systems, but they're not large enough to have really change their directions further on. So, a little change at first makes a big change later. Host: Yeah. Paul Bookout: So, they want to get off to be able to do that, make those little changes. Most of the payloads that are going to lunar orbit, what they're wanting to do is slow down because the ICPS, you know, is launching Orion into this distant retrograde orbit. And, you know, way past the moon. Host: Yeah. Paul Bookout: So, it has a lot of velocity heading that way, and if the payloads don't slow down, they'll just go flying past the moon. The moon can't, doesn't have enough gravity to pull them back into an orbit. And, some of them, even though they are going to the moon, they'll actually fly past the moon, and it may take a month or so for them to come back, to slow down enough to come back and get hooked into the moon's gravity and start orbiting the moon. Host: Oh, wow. Paul Bookout: So, it's not a direct flight into the moon orbit, just because they don't have the propulsion systems large enough to be able to do that. Host: So, is it fair to say they're all going to be in a very similar orbit, or are they all going to kind of go their respective directions? Paul Bookout: They're going to do their respective ways. Host: Okay. Paul Bookout: Some of them wants to do in the crater, so they're going to be going to the pole system, up to the poles to look see if there's ice up in there. And, some of them will just be doing a regular geosynchronous type of orbit. Host: Okay. Paul Bookout: Type thing. Host: All right. Paul Bookout: We talked about where these, what the payloads are and where they're going to want to get off. To be able to allow them to get off, again, we have to have a deployment system where, again, some of the primary requirements for EM-1 was or SLS is to do no harm and to have minimal impact to the vehicle. Host: Yes. Paul Bookout: Well, to do that latter one, what we've come up with a system is that we will receive an energy, the avionics unit for deploying the secondary payloads will receive an energy pulse for, from Orion. Or, I'm sorry. Will receive an energy pulse from the upper stage once Orion has already left and the upper stage has gone through its disposal maneuvers. That means burning off extra fuel and everything making it safe. Right before it shuts down, it will turn on the avionics unit for deploying the secondary payloads. Then, the upper stage turns off. So, we wake up, and we've got our own internal battery system. And, each payload is inside of a dispenser, and so, the dispenser operates as the, has a spring-loaded lid. And, the payloads inside are installed by compressing the spring. So, when the, when it's time for that particular payload to be deployed, we get an energy pulse from the avionics unit sent to the dispenser to open the door. The door flings open, and then the secondary payload is pushed out by springs. So, that's how they're deployed. Host: Okay. So, like a, so, like an SLS jack in the box. [laughter] Paul Bookout: If you will. Host: That's what I'm imagining. Obviously, it's going to shoot out. Paul Bookout: We have pulled those analogies before, but I'll let you state it. Host: And then, I guess there's, you get this power pulse that's going to, I guess, be directed to whatever seven is going to be part of bus stop one, and whatever the next ones for bus stop two. Paul Bookout: Correct. Host: Okay. Paul Bookout: And, they'll be deployed, if there's multiple at a particular bus stop, they'll be deployed a minute or two away from each other, after each other because we don't want to be able to deploy one and then deploy another one right behind it. Host: Yeah. Paul Bookout: And then, they have recontact. Host: So, I'm trying to imagine the way everything is situated in my head, and at this part of the flight when you're starting to deploy these secondary payloads, what does, what does the rocket, I guess, or what does the piece that's actually flying, what does it look like? I guess you have Orion and then there's this deployment system, and then there's, is it the upper stage behind it? Paul Bookout: Okay. So, once we've launched. Host: Yeah. Paul Bookout: After about two minutes, the solar rocket motors are. David Smith: Jettisoned. Paul Bookout: Jettisoned. And then, the core stage lifts the rest of the vehicle up into orbit. And, after that time, when the core stage is spent, then it'll be jettisoned. And then, you'll have your upper stage and your Orion spacecraft which of course the secondary payloads are still in part of that. And then, then, it'll go into what they call a translunar injection that's basically the upper stage will ignite and put Orion into its mission profile going past the moon. Host: So, at this point, right before it ignites, it's still in, I guess, Earth orbit, and the translunar injection gets it to the moon. Paul Bookout: Correct. Host: Okay. Paul Bookout: Okay. So, once the upper stage has spent its fuel, the Orion spacecraft will separate, okay? From the upper stage. So, it'll go through on to its mission. And then, about 30 minutes later, 20, 30 minutes later, the secondary payloads will start their deployment. Host: I see. Okay. Paul Bookout: So, Orion is well away and actually speeding faster away from the upper stage. Host: Yeah. Paul Bookout: The upper stage, once it goes through its disposal maneuver, is actually flying kind of, you would say, backwards, engine first, towards the moon. Host: Oh. Paul Bookout: So, the secondary payloads will be ejected out the other direction. So. Host: Okay. So, so. Paul Bookout: So, when they're deployed, the ICPS won't run back into them. Host: That's right. Paul Bookout: Okay. So, they'll be deployed in the other direction. Host: But, now, Orion is going in, it's doing its own thing. Paul Bookout: Correct. Host: Because it did its job. It delivered Orion. That's the primary payload. Now, it's off. But, the secondary payloads are still part of this upper stage. They haven't gone with Orion. They're totally separate. Paul Bookout: Correct. They have their own. Host: So, it's like, they're kind of doing, they're going. Paul Bookout: Yeah. Host: Different ways. Interesting. Paul Bookout: Yeah, they have their own mission profiles going in all different directions. Host: Okay. Okay. I don't know why that wasn't clear to me before but thank you. All right. So, I guess kind of backing up from there, you're talking about the solid rocket boosters are disposed. The core stage is disposed. Where are all these pieces going? Paul Bookout: Okay. Depending on their mission profile, all the secondary payloads are going to end of missions at different places. Some of them will be actually crashing into the moon, and that's common where the other countries and their lunar missions depositing on the moon. Some will, one or two will burn up in Earth's atmosphere as it comes back. Some of the other ones that are going out into deep space, of course, just keep going. The CuSP, which is going to solar. I'm sorry. CuSP, which is going to the sun's vicinity will just stay out there and eventually be pulled into the sun. Host: Okay. Host: So, that's all the secondary payloads. Paul Bookout: Correct. And, for each mission, each payload that's launched on U.S. rockets, they all have to have an end of mission plan. What are they going to do to end their mission, not just to be left out there as space junk. Because that's, we're having, sorry. We're starting to have a lot of problems with, as you know, there's a lot of space junk around Earth. Host: Oh, yeah. Paul Bookout: And, you don't want that same situation around other planets, too. Host: That's fair. That's fair. And, that's why, that's part of the, I mean, this is going back, but Cassini, right? That was the whole. It did its thing, and instead of just letting it be. It had a controlled entry into Saturn so that it didn't contaminate any other. Paul Bookout: Exactly. Yes. Host: Any other bodies. Yes, yes, of course. Paul Bookout: And, it doesn't matter what size you are. Host: Yeah. Paul Bookout: Even these small CubeSats have to have an end of mission. Host: Have to have an end of mission. Paul Bookout: Yes. Host: Awesome. But, I did want to go back to some of the earlier parts of the mission, right after launch. You know, you're talking about solid rocket boosters separating being. David Smith: Those go into the ocean. Host: Ocean? Okay. David Smith: Still, but they're not recovered this time. Host: Oh, okay. David Smith: You know, for shuttle, they were recovered. This time, it's too difficult. They're too large. So, they're just going to sink. Host: Okay. [00:48:19] David Smith: The external tank is, it can't go into orbit, so it's kind of lofted in such a way that it'll break up over the Indian Ocean safely. Host: Ah. David Smith: So, it's a very large tank. You know, this is much larger than the external tank of shuttle, so it's very important that it break up safely. So, that's, that's why you need the upper stage to actually bring the payload up into a circular orbit around the Earth. Otherwise, the payload would go down with the core module as well. Host: Okay. Okay. And, what about the, I guess, the upper stage. You said it's going to be doing this deployment, but then, after it deploys [inaudible]. David Smith: It's heliocentric. It goes into a sun, heliocentric disposal. Host: Sun heliocentric disposal. David Smith: So, it kind of goes away, and we should, hopefully, not see it again. Host: Okay. All right. That's a very nice summary of EM-1, and I feel like there's so much more to talk about. I kind of wanted to get into, you know, where are we now with SLS, all the history of it. So, I think we should take a break and just sort of let this one be Episode 41. We'll come back, and we'll do Episode 42 and just sort of get into the process behind building the SLS and then the journeys of where it's going to go and beyond. So, guys, thank you so much for coming on. We'll take a break. I'll see you in a few minutes. And, for everyone else, I guess we'll see you for the next episode. David Smith: All right. David Smith: Great, thank you. Look forward to it. Paul Bookout: Thank you. [ Music ] Houston, go ahead. [ Inaudible Comment ] [inaudible] for all mankind. Not because they are easy, but because they are hard. Welcome to space [echo]. Host: Hey, thanks for sticking around. So, the best places to follow development and delivery of the rocket as we test the major components and deliver it piece by piece to the Kennedy Space Center are on the social media channels on the web for the Space Launch System. So, first the website. You can go to www.nasa.gov/ guess what? SLS. That's where you can get the latest, the greatest on the Space Launch System. On Twitter, it's @nasa underscore SLS. On Facebook, it's NASASLS, that's one word. Or, this is one of the things that actually David Smith wrote. You can actually search SLS Mission Planner's Guide. And, it's a document that you can find on the web. You can download it, and it actually has a lot of great information on just the whole scope of the Space Launch System. We're really looking forward to the first launch of SLS and Orion from the Kennedy in a couple years. Sounds like we're well on our way to the pad, and we'll be launching astronauts back to the moon in just a few short years. If you have questions on SLS and its development, use the hashtag asknasa on your favorite platform. Just go to the Johnson accounts. Those are the ones we look at. The NASA Johnson Space Center accounts on Facebook, Twitter, and Instagram. You can send an idea or a question, and we'll make sure to mention it's for, or just make sure to mention it's for Houston, We Have a Podcast, and we'll bring it up in a later episode. Or, maybe address it in an entire episode. The whole episode will be dedicated to the question. Who knows? So, this podcast was recorded on March 20, 2018. Thanks to Alex Perryman, Rachel Craft, Laura Reshawn [assumed spelling], Kelly Humphries, Pat Ryan, Tyler Martin, Bev Perry, and all the folks at the Marshall Spaceflight Center for coming on to help to put this together. Thanks again to Dr. Paul Bookout and Mr. David Smith for coming on the show. We'll be back next week with part two.

Vitamin C supplementation and the common cold--was Linus Pauling right or wrong?

PubMed

Hemilä, H

1997-01-01

In 1970 Linus Pauling claimed that vitamin C prevents and alleviates the episodes of the common cold. Pauling was correct in concluding from trials published up till then, that in general vitamin C does have biological effects on the common cold, but he was rather over-optimistic as regards the size of benefit. His quantitative conclusions were based on a single placebo-controlled trial on schoolchildren in a skiing camp in the Swiss Alps, in which a significant decrease in common cold incidence and duration in the group administered 1 g/day of vitamin C was found. As children in a skiing camp are not a representative sample of the general population, Pauling's extrapolation to the population at large was too bold, erring as to the magnitude of the effect. Nevertheless, Pauling's general conclusion that vitamin C has physiological effects on the common cold is of major importance as it conflicts with the prevailing consensus that the only physiological effect of vitamin C on human beings is to prevent scurvy.

[Invariants of the anthropometrical proportions].

PubMed

Smolianinov, V V

2012-01-01

In this work a general interpretation of a modulor as scales of segments proportions of anthropometrical modules (extremities and a body) is made. The objects of this study were: 1) to reason the idea of the growth modulor; 2) using the modern empirical data, to prove the validity of a principle of linear similarity for anthropometrical segments; 3) to specify the system of invariants for constitutional anthropometrics.

Line segment extraction for large scale unorganized point clouds

NASA Astrophysics Data System (ADS)

Lin, Yangbin; Wang, Cheng; Cheng, Jun; Chen, Bili; Jia, Fukai; Chen, Zhonggui; Li, Jonathan

2015-04-01

Line segment detection in images is already a well-investigated topic, although it has received considerably less attention in 3D point clouds. Benefiting from current LiDAR devices, large-scale point clouds are becoming increasingly common. Most human-made objects have flat surfaces. Line segments that occur where pairs of planes intersect give important information regarding the geometric content of point clouds, which is especially useful for automatic building reconstruction and segmentation. This paper proposes a novel method that is capable of accurately extracting plane intersection line segments from large-scale raw scan points. The 3D line-support region, namely, a point set near a straight linear structure, is extracted simultaneously. The 3D line-support region is fitted by our Line-Segment-Half-Planes (LSHP) structure, which provides a geometric constraint for a line segment, making the line segment more reliable and accurate. We demonstrate our method on the point clouds of large-scale, complex, real-world scenes acquired by LiDAR devices. We also demonstrate the application of 3D line-support regions and their LSHP structures on urban scene abstraction.

Riparian Land Use/Land Cover Data for Five Study Units in the Nutrient Enrichment Effects Topical Study of the National Water-Quality Assessment Program

USGS Publications Warehouse

Johnson, Michaela R.; Buell, Gary R.; Kim, Moon H.; Nardi, Mark R.

2007-01-01

This dataset was developed as part of the National Water-Quality Assessment (NAWQA) Program, Nutrient Enrichment Effects Topical (NEET) study for five study units distributed across the United States: Apalachicola-Chattahoochee-Flint River Basin, Central Columbia Plateau-Yakima River Basin, Central Nebraska Basins, Potomac River Basin and Delmarva Peninsula, and White, Great and Little Miami River Basins. One hundred forty-three stream reaches were examined as part of the NEET study conducted 2003-04. Stream segments, with lengths equal to the logarithm of the basin area, were delineated upstream from the downstream ends of the stream reaches with the use of digital orthophoto quarter quadrangles (DOQQ) or selected from the high-resolution National Hydrography Dataset (NHD). Use of the NHD was necessary when the stream was not distinguishable in the DOQQ because of dense tree canopy. The analysis area for each stream segment was defined by a buffer beginning at the segment extending to 250 meters lateral to the stream segment. Delineation of land use/land cover (LULC) map units within stream segment buffers was conducted using on-screen digitizing of riparian LULC classes interpreted from the DOQQ. LULC units were mapped using a classification strategy consisting of nine classes. National Wetlands Inventory (NWI) data were used to aid in wetland classification. Longitudinal transect sampling lines offset from the stream segments were generated and partitioned into the underlying LULC types. These longitudinal samples yielded the relative linear extent and sequence of each LULC type within the riparian zone at the segment scale. The resulting areal and linear LULC data filled in the spatial-scale gap between the 30-meter resolution of the National Land Cover Dataset and the reach-level habitat assessment data collected onsite routinely for NAWQA ecological sampling. The final data consisted of 12 geospatial datasets: LULC within 25 meters of the stream reach (polygon); LULC within 50 meters of the stream reach (polygon); LULC within 50 meters of the stream segment (polygon); LULC within 100 meters of the stream segment (polygon); LULC within 150 meters of the stream segment (polygon); LULC within 250 meters of the stream segment (polygon); frequency of gaps in woody vegetation LULC at the reach scale (arc); stream reaches (arc); longitudinal LULC at the reach scale (arc); frequency of gaps in woody vegetation LULC at the segment scale (arc); stream segments (arc); and longitudinal LULC at the segment scale (arc).

A Demonstration to Assess Effectiveness, Suitability, and Survivability With the Missions and Means Framework

DTIC Science & Technology

2012-12-01

A Demonstration to Assess Effectiveness, Suitability, and Survivability With the Missions and Means Framework by Beth S . Ward, Paul J...Tanenbaum, Keon U. Burley, Paul H. Deitz, Britt E. Bray, Richard S . Sandmeyer, and Jack H. Sheehan ARL-TR-6271 December 2012...Demonstration to Assess Effectiveness, Suitability, and Survivability With the Missions and Means Framework Beth S . Ward, Paul J. Tanenbaum, and Keon U

Privilege: The Making of an Adolescent Elite at St. Paul's School. Princeton Studies in Cultural Sociology

ERIC Educational Resources Information Center

Khan, Shamus Rahman

2012-01-01

As one of the most prestigious high schools in the nation, St. Paul's School in Concord, New Hampshire, has long been the exclusive domain of America's wealthiest sons. But times have changed. Today, a new elite of boys and girls is being molded at St. Paul's, one that reflects the hope of openness but also the persistence of inequality. In…

Magnetic and Structural Characterization of Fe-Ga Using Kerr Microscopy and Neutron Scattering

DTIC Science & Technology

2010-01-01

117 4.6 Schematic of triple axes single crystal neutron diffractometer (left). TriCS intrument at Paul Scherrer Institut, Switzerland (right...Therefore, USANS data is one-dimensional. 4.3.3 Single Crystal Neutron Diffraction The single crystal neutron diffractometer, TriCS at Paul Scherrer...crystal neutron diffractometer (left). TriCS intrument at Paul Scherrer Institut, Switzerland (right) [106] 4.4 Unpolarized SANS In this section, SANS

A Biophysical-Computational Perspective of Breast Cancer Pathogenesis and Treatment Response

DTIC Science & Technology

2008-03-01

or for monitoring therapy responsiveness. In addition, we recently began a fruitful collaboration with Dr. Paul Hansma from UC Santa Barbara who has...Inactivation of the apoptotic effector Apaf-1 in malignant melanoma. Nature 409, 207-211 (2001). 44. Gifford, G., Paul , J., Vasey, P.A., Kaye, S.B...clustering. Data in parenthesis are 95% confidence intervals. Tissue Diagnostic Instrument Paul Hansma, Hongmei Yu, David Schultz, Azucena Rodriguez

Changes in abundance of vascular plants under varying silvicultural systems at the Forest Ecosystem Research and Demonstration Area, Paul Smiths, New York

Treesearch

Mark J. Twery; Elizabeth Olson; Gary L. Wade; Michael. Rechlin

2013-01-01

The Forest Ecosystem Research and Demonstration Area (FERDA) was established in 1998 adjacent to the Visitor Interpretive Center (VIC) for the Adirondack Park in Paul Smiths, NY, to provide visitors with first-hand exposure to forest management activities and to provide research opportunities for scientists and students at Paul Smith's College. This research note...

Non-linear dynamical classification of short time series of the rössler system in high noise regimes.

PubMed

Lainscsek, Claudia; Weyhenmeyer, Jonathan; Hernandez, Manuel E; Poizner, Howard; Sejnowski, Terrence J

2013-01-01

Time series analysis with delay differential equations (DDEs) reveals non-linear properties of the underlying dynamical system and can serve as a non-linear time-domain classification tool. Here global DDE models were used to analyze short segments of simulated time series from a known dynamical system, the Rössler system, in high noise regimes. In a companion paper, we apply the DDE model developed here to classify short segments of encephalographic (EEG) data recorded from patients with Parkinson's disease and healthy subjects. Nine simulated subjects in each of two distinct classes were generated by varying the bifurcation parameter b and keeping the other two parameters (a and c) of the Rössler system fixed. All choices of b were in the chaotic parameter range. We diluted the simulated data using white noise ranging from 10 to -30 dB signal-to-noise ratios (SNR). Structure selection was supervised by selecting the number of terms, delays, and order of non-linearity of the model DDE model that best linearly separated the two classes of data. The distances d from the linear dividing hyperplane was then used to assess the classification performance by computing the area A' under the ROC curve. The selected model was tested on untrained data using repeated random sub-sampling validation. DDEs were able to accurately distinguish the two dynamical conditions, and moreover, to quantify the changes in the dynamics. There was a significant correlation between the dynamical bifurcation parameter b of the simulated data and the classification parameter d from our analysis. This correlation still held for new simulated subjects with new dynamical parameters selected from each of the two dynamical regimes. Furthermore, the correlation was robust to added noise, being significant even when the noise was greater than the signal. We conclude that DDE models may be used as a generalizable and reliable classification tool for even small segments of noisy data.

Non-Linear Dynamical Classification of Short Time Series of the Rössler System in High Noise Regimes

PubMed Central

Lainscsek, Claudia; Weyhenmeyer, Jonathan; Hernandez, Manuel E.; Poizner, Howard; Sejnowski, Terrence J.

2013-01-01

Time series analysis with delay differential equations (DDEs) reveals non-linear properties of the underlying dynamical system and can serve as a non-linear time-domain classification tool. Here global DDE models were used to analyze short segments of simulated time series from a known dynamical system, the Rössler system, in high noise regimes. In a companion paper, we apply the DDE model developed here to classify short segments of encephalographic (EEG) data recorded from patients with Parkinson’s disease and healthy subjects. Nine simulated subjects in each of two distinct classes were generated by varying the bifurcation parameter b and keeping the other two parameters (a and c) of the Rössler system fixed. All choices of b were in the chaotic parameter range. We diluted the simulated data using white noise ranging from 10 to −30 dB signal-to-noise ratios (SNR). Structure selection was supervised by selecting the number of terms, delays, and order of non-linearity of the model DDE model that best linearly separated the two classes of data. The distances d from the linear dividing hyperplane was then used to assess the classification performance by computing the area A′ under the ROC curve. The selected model was tested on untrained data using repeated random sub-sampling validation. DDEs were able to accurately distinguish the two dynamical conditions, and moreover, to quantify the changes in the dynamics. There was a significant correlation between the dynamical bifurcation parameter b of the simulated data and the classification parameter d from our analysis. This correlation still held for new simulated subjects with new dynamical parameters selected from each of the two dynamical regimes. Furthermore, the correlation was robust to added noise, being significant even when the noise was greater than the signal. We conclude that DDE models may be used as a generalizable and reliable classification tool for even small segments of noisy data. PMID:24379798

Spherical cloaking using nonlinear transformations for improved segmentation into concentric isotropic coatings.

PubMed

Qiu, Cheng-Wei; Hu, Li; Zhang, Baile; Wu, Bae-Ian; Johnson, Steven G; Joannopoulos, John D

2009-08-03

Two novel classes of spherical invisibility cloaks based on nonlinear transformation have been studied. The cloaking characteristics are presented by segmenting the nonlinear transformation based spherical cloak into concentric isotropic homogeneous coatings. Detailed investigations of the optimal discretization (e.g., thickness control of each layer, nonlinear factor, etc.) are presented for both linear and nonlinear spherical cloaks and their effects on invisibility performance are also discussed. The cloaking properties and our choice of optimal segmentation are verified by the numerical simulation of not only near-field electric-field distribution but also the far-field radar cross section (RCS).

Paul Bert

NASA Technical Reports Server (NTRS)

Colin, J.

1978-01-01

This biographical article on Paul Bert highlights his studies on the physiology of respiration and barometric pressure and, in particular his contributions to the understanding of hypoxia, hyperoxia and anesthesia.

Paul Davis Restoration Information Sheet

EPA Pesticide Factsheets

Paul Davis Restoration (the Company) is located in Nicholasville, Kentucky. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Lexington, Kentucky.

Modeling and Analysis of Resolve and Morale for the Long War’

DTIC Science & Technology

2007-12-01

Alexandria, Virginia, 1995 Bratley, Paul , Bennett L. Fox, and Linus E. Schrage, A Guide to Simulation (2nd ed.), Springer-Verlag, New York, 1987 Bross... Paul J., Measuring the “Will to Fight” in Simulation, Lockheed Martin Corporation, 73rd MORS Symposium Working Group 33 Presentation, DTIC...115, 2004 MacKay, Niall, “Lanchester combat models”, Mathematics Today, Volume 42, Number 5, Pages 170-173, 2006 Macioce, Paul , “Viscoelastic

Non-Lethal Weapons for Today’s Operations

DTIC Science & Technology

2011-01-01

Division Chief Lieutenant Colonel Paul L. Scholl : paul.scholl@usmc.mil Acquisition Division Chief Kevin J. Swenson: kevin.swenson@usmc.mil Technology...Division Chief David B. Law: david.b.law1@usmc.mil Health Effects Officer Mary R. Williams : mary.r.williams1.ctr@usmc.mil Annual Report Editorial Board...Douglas J. Jerothe Lieutenant Colonel Paul L. Scholl Susan D. LeVine Kevin J. Swenson Kelley S. Hughes Alicia J. Owsiak Publication Management Bethel

College and University Speech Codes in the Aftermath of R.A.V v. City of St. Paul.

ERIC Educational Resources Information Center

Fraleigh, Douglas

In the case of RAV v. City of St. Paul, a teenager was charged with violating the city's Bias-Motivated Crime Ordinance after being accused of burning a cross inside the fenced yard of a black family. In a 9-0 decision, the Supreme Court struck down the St. Paul ordinance, a decision which raised a question as to whether many college and…

Teaching to Make Disciples in a Higher Education Online Learning Environment: A Comparison of the Literature of Online Learning, the Objectives and Practices of Three Christian Colleges, and the Letters of Paul

ERIC Educational Resources Information Center

Morris, Raymond E.

2012-01-01

This dissertation explores engaging students in spiritual formation and discipleship in the online environment. This researcher begins with the proposition that the letters of Paul are examples of distance teaching and distance learning. The effectiveness of the letters of Paul in engaging their recipients in spiritual formation and discipleship…

Development of a Robust Static Punch Experiment for Screening Unprocessed Ultra-High Molecular Weight Polyethylene (UHMWPE) Unidirectional Cross-Ply Material

DTIC Science & Technology

2014-09-01

Cross-Ply Material by David Gray, Robert Kaste , and Paul Moy ARL-TR-7090 September 2014...Screening Unprocessed Ultra-High Molecular Weight Polyethylene (UHMWPE) Unidirectional Cross-Ply Material David Gray, Robert Kaste , and Paul...ELEMENT NUMBER 6. AUTHOR(S) David Gray, Robert Kaste , and Paul Moy 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7

Space Weather Editors in Transition: Hail and Farewell

NASA Astrophysics Data System (ADS)

Knipp, Delores J.

2017-02-01

I hope you will join me in welcoming Dr. Daniel Welling of University of Michigan and Dr. T. Paul O'Brien of the Aerospace Corporation to the Space Weather (SWE) editorial team. Dan and Paul have answered the call to fill the shoes of two departing editors: Dr. Howard Singer and Dr. Barbara Giles. Dan brings insight related to space weather model development, while Paul brings expertise in the geospace radiation environment.

Joint tumor segmentation and dense deformable registration of brain MR images.

PubMed

Parisot, Sarah; Duffau, Hugues; Chemouny, Stéphane; Paragios, Nikos

2012-01-01

In this paper we propose a novel graph-based concurrent registration and segmentation framework. Registration is modeled with a pairwise graphical model formulation that is modular with respect to the data and regularization term. Segmentation is addressed by adopting a similar graphical model, using image-based classification techniques while producing a smooth solution. The two problems are coupled via a relaxation of the registration criterion in the presence of tumors as well as a segmentation through a registration term aiming the separation between healthy and diseased tissues. Efficient linear programming is used to solve both problems simultaneously. State of the art results demonstrate the potential of our method on a large and challenging low-grade glioma data set.

Design and rationale of the ANALYZE ST study: a prospective, nonrandomized, multicenter ST monitoring study to detect acute coronary syndrome events in implantable cardioverter-defibrillator patients.

PubMed

Gibson, C Michael; Krucoff, Mitchell; Kirtane, Ajay J; Rao, Sunil V; Mackall, Judith A; Matthews, Ray; Saba, Samir; Waksman, Ron; Holmes, David

2014-10-01

In the setting of ST-segment elevation myocardial infarction, timely restoration of normal blood flow is associated with improved myocardial salvage and survival. Despite improvements in door-to-needle and door-to-balloon times, there remains an unmet need with respect to improved symptom-to-door times. A prior report of an implanted device to monitor ST-segment deviation demonstrated very short times to reperfusion among patients with an acute coronary syndrome (ACS) with documented thrombotic occlusion. The goal of the ANALYZE ST study is to evaluate the safety and effectiveness of a novel ST-segment monitoring feature using an existing implantable cardioverter-defibrillator (ICD) among patients with known coronary artery disease. The ANALYZE ST study is a prospective, nonrandomized, multicenter, pivotal Investigational Device Exemption study enrolling 5,228 patients with newly implanted ICD systems for standard clinical indications who also have a documented history of coronary artery disease. Patients will be monitored for 48 months, during which effectiveness of the device for the purpose of early detection of cardiac injury will be evaluated by analyzing the sensitivity of the ST monitoring feature to identify clinical ACS events. In addition, the safety of the ST monitoring feature will be evaluated through the assessment of the percentage of patients for which monitoring produces a false-positive event over the course of 12 months. The ANALYZE ST trial is testing the hypothesis that the ST monitoring feature in the Fortify ST ICD system (St. Jude Medical, Inc., St. Paul, MN) (or other ICD systems with the ST monitoring feature) will accurately identify patients with clinical ACS events. Copyright © 2014 Mosby, Inc. All rights reserved.

Interactive vs. automatic ultrasound image segmentation methods for staging hepatic lipidosis.

PubMed

Weijers, Gert; Starke, Alexander; Haudum, Alois; Thijssen, Johan M; Rehage, Jürgen; De Korte, Chris L

2010-07-01

The aim of this study was to test the hypothesis that automatic segmentation of vessels in ultrasound (US) images can produce similar or better results in grading fatty livers than interactive segmentation. A study was performed in postpartum dairy cows (N=151), as an animal model of human fatty liver disease, to test this hypothesis. Five transcutaneous and five intraoperative US liver images were acquired in each animal and a liverbiopsy was taken. In liver tissue samples, triacylglycerol (TAG) was measured by biochemical analysis and hepatic diseases other than hepatic lipidosis were excluded by histopathologic examination. Ultrasonic tissue characterization (UTC) parameters--Mean echo level, standard deviation (SD) of echo level, signal-to-noise ratio (SNR), residual attenuation coefficient (ResAtt) and axial and lateral speckle size--were derived using a computer-aided US (CAUS) protocol and software package. First, the liver tissue was interactively segmented by two observers. With increasing fat content, fewer hepatic vessels were visible in the ultrasound images and, therefore, a smaller proportion of the liver needed to be excluded from these images. Automatic-segmentation algorithms were implemented and it was investigated whether better results could be achieved than with the subjective and time-consuming interactive-segmentation procedure. The automatic-segmentation algorithms were based on both fixed and adaptive thresholding techniques in combination with a 'speckle'-shaped moving-window exclusion technique. All data were analyzed with and without postprocessing as contained in CAUS and with different automated-segmentation techniques. This enabled us to study the effect of the applied postprocessing steps on single and multiple linear regressions ofthe various UTC parameters with TAG. Improved correlations for all US parameters were found by using automatic-segmentation techniques. Stepwise multiple linear-regression formulas where derived and used to predict TAG level in the liver. Receiver-operating-characteristics (ROC) analysis was applied to assess the performance and area under the curve (AUC) of predicting TAG and to compare the sensitivity and specificity of the methods. Best speckle-size estimates and overall performance (R2 = 0.71, AUC = 0.94) were achieved by using an SNR-based adaptive automatic-segmentation method (used TAG threshold: 50 mg/g liver wet weight). Automatic segmentation is thus feasible and profitable.

Analysis of continuously rotating quadrupole focusing channels using generalized Courant-Snyder theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chung, Moses; Qin, Hong; Gilson, Erik

2013-01-01

By extending the recently developed generalized Courant-Snyder theory for coupled transverse beam dynamics, we have constructed the Gaussian beam distribution and its projections with arbitrary mode emittance ratios. The new formulation has been applied to a continuously-rotating quadrupole focusing channel because the basic properties of this channel are known theoretically and could also be investigated experimentally in a compact setup such as the linear Paul trap configuration. The new formulation retains a remarkably similar mathematical structure to the original Courant-Snyder theory, and thus provides a powerful theoretical tool to investigate coupled transverse beam dynamics in general and more complex linearmore » focusing channels.« less

Measuring the charge density of a tapered optical fiber using trapped microparticles.

PubMed

Kamitani, Kazuhiko; Muranaka, Takuya; Takashima, Hideaki; Fujiwara, Masazumi; Tanaka, Utako; Takeuchi, Shigeki; Urabe, Shinji

2016-03-07

We report the measurements of charge density of tapered optical fibers using charged particles confined in a linear Paul trap at ambient pressure. A tapered optical fiber is placed across the trap axis at a right angle, and polystyrene microparticles are trapped along the trap axis. The distance between the equilibrium position of a positively charged particle and the tapered fiber is used to estimate the amount of charge per unit length of the fiber without knowing the amount of charge of the trapped particle. The charge per unit length of a tapered fiber with a diameter of 1.6 μm was measured to be 2-1+3×10 -11 C/m.

In vivo measurement of spinal column viscoelasticity--an animal model.

PubMed

Hult, E; Ekström, L; Kaigle, A; Holm, S; Hansson, T

1995-01-01

The goal of this study was to measure the in vivo viscoelastic response of spinal motion segments loaded in compression using a porcine model. Nine pigs were used in the study. The animals were anaesthetized and, using surgical techniques, four intrapedicular screws were inserted into the vertebrae of the L2-L3 motion segment. A miniaturized servohydraulic exciter capable of compressing the motion segment was mounted on to the screws. In six animals, a loading scheme consisting of 50 N and 100 N of compression, each applied for 10 min, was used. Each loading period was followed by 10 min restitution with zero load. The loading scheme was repeated four times. Three animals were examined for stiffening effects by consecutively repeating eight times 50 N loading for 5 min followed by 5 min restitution with zero load. This loading scheme was repeated using a 100 N load level. The creep-recovery behavior of the motion segment was recorded continuously. Using non-linear regression techniques, the experimental data were used for evaluating the parameters of a three-parameter standard linear solid model. Correlation coefficients of the order of 0.85 or higher were obtained for the three independent parameters of the model. A survey of the data shows that the viscous deformation rate was a function of the load level. Also, repeated loading at 100 N seemed to induce long-lasting changes in the viscoelastic properties of the porcine lumbar motion segment.

Inferring the most probable maps of underground utilities using Bayesian mapping model

NASA Astrophysics Data System (ADS)

Bilal, Muhammad; Khan, Wasiq; Muggleton, Jennifer; Rustighi, Emiliano; Jenks, Hugo; Pennock, Steve R.; Atkins, Phil R.; Cohn, Anthony

2018-03-01

Mapping the Underworld (MTU), a major initiative in the UK, is focused on addressing social, environmental and economic consequences raised from the inability to locate buried underground utilities (such as pipes and cables) by developing a multi-sensor mobile device. The aim of MTU device is to locate different types of buried assets in real time with the use of automated data processing techniques and statutory records. The statutory records, even though typically being inaccurate and incomplete, provide useful prior information on what is buried under the ground and where. However, the integration of information from multiple sensors (raw data) with these qualitative maps and their visualization is challenging and requires the implementation of robust machine learning/data fusion approaches. An approach for automated creation of revised maps was developed as a Bayesian Mapping model in this paper by integrating the knowledge extracted from sensors raw data and available statutory records. The combination of statutory records with the hypotheses from sensors was for initial estimation of what might be found underground and roughly where. The maps were (re)constructed using automated image segmentation techniques for hypotheses extraction and Bayesian classification techniques for segment-manhole connections. The model consisting of image segmentation algorithm and various Bayesian classification techniques (segment recognition and expectation maximization (EM) algorithm) provided robust performance on various simulated as well as real sites in terms of predicting linear/non-linear segments and constructing refined 2D/3D maps.

Joint graph cut and relative fuzzy connectedness image segmentation algorithm.

PubMed

Ciesielski, Krzysztof Chris; Miranda, Paulo A V; Falcão, Alexandre X; Udupa, Jayaram K

2013-12-01

We introduce an image segmentation algorithm, called GC(sum)(max), which combines, in novel manner, the strengths of two popular algorithms: Relative Fuzzy Connectedness (RFC) and (standard) Graph Cut (GC). We show, both theoretically and experimentally, that GC(sum)(max) preserves robustness of RFC with respect to the seed choice (thus, avoiding "shrinking problem" of GC), while keeping GC's stronger control over the problem of "leaking though poorly defined boundary segments." The analysis of GC(sum)(max) is greatly facilitated by our recent theoretical results that RFC can be described within the framework of Generalized GC (GGC) segmentation algorithms. In our implementation of GC(sum)(max) we use, as a subroutine, a version of RFC algorithm (based on Image Forest Transform) that runs (provably) in linear time with respect to the image size. This results in GC(sum)(max) running in a time close to linear. Experimental comparison of GC(sum)(max) to GC, an iterative version of RFC (IRFC), and power watershed (PW), based on a variety medical and non-medical images, indicates superior accuracy performance of GC(sum)(max) over these other methods, resulting in a rank ordering of GC(sum)(max)>PW∼IRFC>GC. Copyright © 2013 Elsevier B.V. All rights reserved.

Vowel Imagery Decoding toward Silent Speech BCI Using Extreme Learning Machine with Electroencephalogram

PubMed Central

Kim, Jongin; Park, Hyeong-jun

2016-01-01

The purpose of this study is to classify EEG data on imagined speech in a single trial. We recorded EEG data while five subjects imagined different vowels, /a/, /e/, /i/, /o/, and /u/. We divided each single trial dataset into thirty segments and extracted features (mean, variance, standard deviation, and skewness) from all segments. To reduce the dimension of the feature vector, we applied a feature selection algorithm based on the sparse regression model. These features were classified using a support vector machine with a radial basis function kernel, an extreme learning machine, and two variants of an extreme learning machine with different kernels. Because each single trial consisted of thirty segments, our algorithm decided the label of the single trial by selecting the most frequent output among the outputs of the thirty segments. As a result, we observed that the extreme learning machine and its variants achieved better classification rates than the support vector machine with a radial basis function kernel and linear discrimination analysis. Thus, our results suggested that EEG responses to imagined speech could be successfully classified in a single trial using an extreme learning machine with a radial basis function and linear kernel. This study with classification of imagined speech might contribute to the development of silent speech BCI systems. PMID:28097128

First-principles study on stability of transition metal solutes in aluminum by analyzing the underlying forces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Wei; Xu, Yichun; Li, Xiangyan

2015-05-07

Although there have been some investigations on behaviors of solutes in metals under strain, the underlying mechanism of how strain changes the stability of a solute is still unknown. To gain such knowledge, first-principles calculations are performed on substitution energy of transition metal solutes in fcc Al host under rhombohedral strain (RS). Our results show that under RS, substitution energy decreases linearly with the increase of outermost d radius r{sub d} of the solute due to Pauli repulsion. The screened Coulomb interaction increases or decreases the substitution energy of a solute on condition that its Pauling electronegativity scale ϕ{sub P}more » is less or greater than that of Al under RS. This paper verifies a linear relation of substitution energy change versus r{sub d} and ϕ{sub P} under RS, which might be instructive for composition design of long life alloys serving in high stress condition.« less

Use of infrared spectroscopy for the determination of electronegativity of rare earth elements.

PubMed

Frost, Ray L; Erickson, Kristy L; Weier, Matt L; McKinnon, Adam R; Williams, Peter A; Leverett, Peter

2004-07-01

Infrared spectroscopy has been used to study a series of synthetic agardite minerals. Four OH stretching bands are observed at around 3568, 3482, 3362, and 3296 cm(-1). The first band is assigned to zeolitic, non-hydrogen-bonded water. The band at 3296 cm(-1) is assigned to strongly hydrogen-bonded water with an H bond distance of 2.72 A. The water in agardites is better described as structured water and not as zeolitic water. Two bands at around 999 and 975 cm(-1) are assigned to OH deformation modes. Two sets of AsO symmetric stretching vibrations were found and assigned to the vibrational modes of AsO(4) and HAsO(4) units. Linear relationships between positions of infrared bands associated with bonding to the OH units and the electronegativity of the rare earth elements were derived, with correlation coefficients >0.92. These linear functions were then used to calculate the electronegativity of Eu, for which a value of 1.1808 on the Pauling scale was found.

The Mobilization of Effort: Sergeants, Patrol Officers, and Productivity in an American Agency.

DTIC Science & Technology

1982-02-01

Berlceley. Cain, M. 1974 Society and the policeman’s role. London: Routledge and Kegan Paul. Chatterton, Michael 1975 Organizational relationships and...Routledge and Kegan Paul. Pike, D. 1981 A comparative analysis of the role of women in police training. Unpublished Ph.D. Dissertation, Yale University...David 1970 Yhe theory of organization. NY: Basic. 1974 ()rranizational work. London: Root ledge and Kegan Paul. Van Maanen , lo’in 1972 Pledging the

Life Cycle Management Commands: Wartime Process or Long-Term Solution?

DTIC Science & Technology

2007-03-31

this memorandum. • 1998: The Director of the Army Acquisition Corps (AAC), Lieutenant General (LTG) Paul Kern, testified before Congress about two...the Army finally determined that PVS did not benefit the Army overall. 17 The Director of the Army Acquisition Corps (AAC), LTG Paul Kern, championed...2 and 3 on pages 10 and 11 of the study. 9 LTG Paul J. Kern, Military Deputy to the ASA(ALT), comments made to the Army Acquisition Corps (AAC

Minutes of the Explosives Safety Seminar (19th) Held at Los Angeles, California, 9-10-11 September 1980. Volume 1

DTIC Science & Technology

1980-01-01

DOUBLE-BASE EXTRUSION COMPOSITIONS ................................... 89 Messrs. Craig E. Johnson and Paul F. Dendor V I GUN PROPELLANT PROPAGATION IN...Mullins and C. F. Baker RESULTS AND ANALYSIS OF STRENGTHENED STEEL BUILDING BLAST TESTS ..... 165 Messrs. Frederic E. Sock, Norval Dobbs, Paul Price and...347 Mr. J. Paul Glenn I viLR SESSION - EXPLOSION CONTAIMENT & VENTING Moderator - Mr. Irving Forsten EXPLOSION CONTAINMENT VESSELS AND M4TERIALS

Another Crossroads? Professional Military Education Two Decades After the Goldwater-Nichols Act and the Skelton Panel

DTIC Science & Technology

2010-04-01

staff including Erin Conaton, Paul Arcangeli, Robert Simmons, Paul Oostburg Sanz, Paul Lewis, Debra Wada, Suzanne McKenna, Vickie Plunkett, Craig ...National Defense University: Lieutenant General Frances C. Wilson, Dr. John Deegan , Jr., and Dr. John W. Yaeger, 16 March 2009. Marine Corps...diversity.” The Washington Post (on line), 10 November 2009. Deegan , John, Jr. “First Step to Academic Excellence: The Faculty.” 14 April 2009

The Inadequacy of Definition and the Utility of a Theory of Hybrid Conflict: Is the Hybrid Threat New?

DTIC Science & Technology

2012-05-17

Era of Persistent Conflict, edited by Paul Brister, William H. Natter III, & Robert R. Tomes, 60-69. Washington, DC: CENSA, 2011. Gott, Kendall G...Conflict.” In Hybrid Warfare and Transnational Threats: Perspectives for an Era of Persistent Conflict, edited by Paul Brister, William H. Natter...Hybrid Warfare and Transnational Threats: Perspectives for an Era of Persistent Conflict, edited by Paul Brister, William H. Natter III, & Robert R

Welcoming nora: a family event.

PubMed

Walsh, Allison J; Walsh, Paul R; Walsh, Jane M; Walsh, Gavin T

2011-01-01

In this column, Allison and Paul Walsh share the story of the birth of Nora, their third baby and their second child to be born at home. Allison and Paul share their individual memories of labor and birth. But their story is only part of the story of Nora's birth. Nora's birth was a family event, with Allison and Paul's other children very much part of the experience. Jane and Gavin share their own memories of their baby sister's birth.

Short of General War: Perspectives on the Use of Military Power in the 21st Century

DTIC Science & Technology

2010-04-01

Paul , MN: Zenith Press, 2004. Hammes’ work is one articulation of this argument. 5. United States Joint Forces Command, “The JOE 2008, Joint Operating...this approach would actually be counterproductive and might be more harmful than beneficial to American interests. According to Paul Sanders, 18...A New Security Strategy for America, Washington, DC: Brookings Institution Press, 1999, p. 55. 50. Paul J. Sanders, “Not the Way to Intervene

Enhancing the Effectiveness of Ad Hoc Units: A Revised Training Model

DTIC Science & Technology

2009-06-01

thank Dr. Kalev “Gunner” Sepp, Dr. Bob McNab, Dr. John Arquilla, Dr. Nancy Roberts, Dr. Susan Hocevar, and Dr. Dorothy Denning for providing their...also want to thank Colonel Paul Warren, Information Operations Branch Chief at U.S. Central Command – Special Operations (SOCCENT), for sponsoring my...Academy of Management Journal, 38 (1), 60-84. Paul M. Nemiroff, Paul M., William, A. Pasmore and David L. Ford, Jr., “The Effects of Two

The first 'molecular disease': a story of Linus Pauling, the intellectual patron.

PubMed

Gormley, Melinda

2007-06-01

In November 1949, chemist Linus Pauling and three colleagues published an article on sickle-cell anemia, a study that opened up new and exciting possibilities for research into such 'molecular diseases'. Even before this celebrated publication appeared in Science, Pauling foresaw its potential benefits and announced it as a medical breakthrough: '... our structural chemistry and understanding of molecules is getting to the point where it should be of assistance in converting medicine into a real science' [Guiles, R. (1949) Discovery of blood disease called key to cancer research. The Detroit Times 13 Sep 1949, Newspaper Clippings 1949n.18, Pauling Papers.]. Their discovery--that this debilitating disorder was caused by an abnormal form of hemoglobin--was borne out of a rich mix of expertise, from Pauling's remarkable intuition to the careful experimental chemistry of his student Harvey A. Itano. It also relied upon technological innovation: a custom-made electrophoresis machine housed at the California Institute of Technology was the perfect tool to reveal fundamental chemical differences between normal and abnormal forms of hemoglobin. Not only did this work establish a new way of looking at inherited diseases, it also stimulated the mass production of the electrophoresis machine as an essential investigative and diagnostic tool. A close inspection of this case study illustrates just how Pauling ran his laboratory and helps to explain how one man could achieve so much over his lifetime.

Evolution of semilocal string networks. II. Velocity estimators

NASA Astrophysics Data System (ADS)

Lopez-Eiguren, A.; Urrestilla, J.; Achúcarro, A.; Avgoustidis, A.; Martins, C. J. A. P.

2017-07-01

We continue a comprehensive numerical study of semilocal string networks and their cosmological evolution. These can be thought of as hybrid networks comprised of (nontopological) string segments, whose core structure is similar to that of Abelian Higgs vortices, and whose ends have long-range interactions and behavior similar to that of global monopoles. Our study provides further evidence of a linear scaling regime, already reported in previous studies, for the typical length scale and velocity of the network. We introduce a new algorithm to identify the position of the segment cores. This allows us to determine the length and velocity of each individual segment and follow their evolution in time. We study the statistical distribution of segment lengths and velocities for radiation- and matter-dominated evolution in the regime where the strings are stable. Our segment detection algorithm gives higher length values than previous studies based on indirect detection methods. The statistical distribution shows no evidence of (anti)correlation between the speed and the length of the segments.

Discrimination between platelet-mediated and coagulation-mediated mechanisms in a model of complex thrombus formation in vivo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadroy, Y.; Horbett, T.A.; Hanson, S.R.

1989-04-01

To study mechanisms of complex thrombus formation in vivo, and to compare the relative antithrombotic effects of anticoagulants and antiplatelet agents, a model was developed in baboons. Segments of collagen-coated tubing followed by two sequentially placed expansion chambers exhibiting disturbed flow patterns were exposed to native blood under laminar flow conditions. The device was incorporated for 1 hour into an exteriorized arteriovenous shunt in baboons under controlled blood flow (20 ml/min). Morphologic evaluation by scanning electron microscopy showed that thrombi associated with collagen were relatively rich in platelets but thrombi in the chambers were rich in fibrin and red cells.more » Deposition of indium 111-labeled platelets was continuously measured with a scintillation camera. Platelet deposition increased in a linear (collagen-coated segment) or exponential (chambers 1 and 2) fashion over time, with values after 40 minutes averaging 24.1 +/- 3.3 x 10(8) platelets (collagen segment), 16.7 +/- 3.4 x 10(8) platelets (chamber 1), and 8.4 +/- 2.4 x 10(8) platelets (chamber 2). Total fibrinogen deposition after 40 minutes was determined by using iodine 125-labeled baboon fibrinogen and averaged 0.58 +/- 0.14 mg in the collagen segment, 1.51 +/- 0.27 mg in chamber 1, and 0.95 +/- 0.25 mg in chamber 2. Plasma levels of beta-thromboglobulin (beta TG), platelet-factor 4 (PF4), and fibrinopeptide A (FPA) increased fourfold to fivefold after 60 minutes of blood exposure to the thrombotic device. Platelet deposition onto the collagen segment, chamber 1, and chamber 2 was linearly dependent on the circulating platelet count. Platelet accumulation in chamber 1 and chamber 2 was also dependent on the presence of the proximal collagen segment.« less

Image segmentation-based robust feature extraction for color image watermarking

NASA Astrophysics Data System (ADS)

Li, Mianjie; Deng, Zeyu; Yuan, Xiaochen

2018-04-01

This paper proposes a local digital image watermarking method based on Robust Feature Extraction. The segmentation is achieved by Simple Linear Iterative Clustering (SLIC) based on which an Image Segmentation-based Robust Feature Extraction (ISRFE) method is proposed for feature extraction. Our method can adaptively extract feature regions from the blocks segmented by SLIC. This novel method can extract the most robust feature region in every segmented image. Each feature region is decomposed into low-frequency domain and high-frequency domain by Discrete Cosine Transform (DCT). Watermark images are then embedded into the coefficients in the low-frequency domain. The Distortion-Compensated Dither Modulation (DC-DM) algorithm is chosen as the quantization method for embedding. The experimental results indicate that the method has good performance under various attacks. Furthermore, the proposed method can obtain a trade-off between high robustness and good image quality.

Automatic segmentation of Leishmania parasite in microscopic images using a modified CV level set method

NASA Astrophysics Data System (ADS)

Farahi, Maria; Rabbani, Hossein; Talebi, Ardeshir; Sarrafzadeh, Omid; Ensafi, Shahab

2015-12-01

Visceral Leishmaniasis is a parasitic disease that affects liver, spleen and bone marrow. According to World Health Organization report, definitive diagnosis is possible just by direct observation of the Leishman body in the microscopic image taken from bone marrow samples. We utilize morphological and CV level set method to segment Leishman bodies in digital color microscopic images captured from bone marrow samples. Linear contrast stretching method is used for image enhancement and morphological method is applied to determine the parasite regions and wipe up unwanted objects. Modified global and local CV level set methods are proposed for segmentation and a shape based stopping factor is used to hasten the algorithm. Manual segmentation is considered as ground truth to evaluate the proposed method. This method is tested on 28 samples and achieved 10.90% mean of segmentation error for global model and 9.76% for local model.

Iris recognition: on the segmentation of degraded images acquired in the visible wavelength.

PubMed

Proença, Hugo

2010-08-01

Iris recognition imaging constraints are receiving increasing attention. There are several proposals to develop systems that operate in the visible wavelength and in less constrained environments. These imaging conditions engender acquired noisy artifacts that lead to severely degraded images, making iris segmentation a major issue. Having observed that existing iris segmentation methods tend to fail in these challenging conditions, we present a segmentation method that can handle degraded images acquired in less constrained conditions. We offer the following contributions: 1) to consider the sclera the most easily distinguishable part of the eye in degraded images, 2) to propose a new type of feature that measures the proportion of sclera in each direction and is fundamental in segmenting the iris, and 3) to run the entire procedure in deterministically linear time in respect to the size of the image, making the procedure suitable for real-time applications.

Paul Feyerabend: Science and the Anarchist.

ERIC Educational Resources Information Center

Science, 1979

1979-01-01

Presents comments on the arguments of Paul Feyerabend toward progression science. The positions held by this philosopher of science are given with accompanying remarks from other philosophers and historians. (SA)

Paul G. Silver (1948-2009)

NASA Astrophysics Data System (ADS)

Solomon, Sean C.

2009-11-01

A pioneer in the novel application of seismic observations to infer the flow field of Earth's mantle and the mechanics of fault zones, Paul Gordon Silver tragically was killed on 7 August in an automobile accident that also took the life of his 22-year-old daughter, Celine. Born and raised in Los Angeles, Calif., Paul received all of his degrees from the University of California. Following receipt of a B.A. in psychology from the University of California (UC), Los Angeles (1970), he pursued a career as a musician for several years. Drawn to Earth science, Paul obtained a B.A. in geology from UC Berkeley, in 1976, and he was recruited by Tom Jordan (now at the University of Southern California) to the graduate program of the Scripps Institution of Oceanography at UC San Diego.

Major Additions to the Linus Pauling Canon

NASA Astrophysics Data System (ADS)

Davenport, Derek A.

2002-08-01

The National Library of Medicine has also just posted a Web site on Linus Pauling in its Profiles of Science series. While by no means as rich as the various Oregon State University sites, it is well worth visiting. There are texts of various speeches (including his Nobel address), many downloadable photographs, correspondence (including a poignant letter to James Watson and Francis Crick concerning their "rival" structures for DNA), and much else besides. There is a certain irony in Linus Pauling being honored by the National Library of Medicine. Ever since his 1949 presidential address to the American Chemical Society, and perhaps earlier, Pauling had been at loggerheads, sometimes acrimoniously so, with the medical establishment. It is easy to imagine him somewhere in the timeless infinitude of the empyrean sporting his characteristic ear-to-ear grin.

Spider monkey ranging patterns in Mexican subtropical forest: do travel routes reflect planning?

PubMed

Valero, Alejandra; Byrne, Richard W

2007-07-01

Although it is well known that frugivorous spider monkeys (Ateles geoffroyi yucatanensis) occupy large home ranges, travelling long distances to reach highly productive resources, little is known of how they move between feeding sites. A 11 month study of spider monkey ranging patterns was carried out at the Otochma'ax Yetel Kooh reserve, Yucatán, Mexico. We followed single individuals for as long as possible each day and recorded the routes travelled with the help of a GPS (Global Positioning System) device; the 11 independently moving individuals of a group were targeted as focal subjects. Travel paths were composed of highly linear segments, each typically ending at a place where some resource was exploited. Linearity of segments did not differ between individuals, and most of the highly linear paths that led to food resources were much longer than the estimate visibility in the woodland canopy. Monkeys do not generally continue in the same ranging direction after exploiting a resource: travel paths are likely to deviate at the site of resource exploitation rather than between such sites. However, during the harshest months of the year consecutive route segments were more likely to retain the same direction of overall movement. Together, these findings suggest that while moving between feeding sites, spider monkeys use spatial memory to guide travel, and even plan more than one resource site in advance.

Task Space Angular Velocity Blending for Real-Time Trajectory Generation

NASA Technical Reports Server (NTRS)

Volpe, Richard A. (Inventor)

1997-01-01

The invention is embodied in a method of controlling a robot manipulator moving toward a target frame F(sub 0) with a target velocity v(sub 0) including a linear target velocity v and an angular target velocity omega(sub 0) to smoothly and continuously divert the robot manipulator to a subsequent frame F(sub 1) by determining a global transition velocity v(sub 1), the global transition velocity including a linear transition velocity v(sub 1) and an angular transition velocity omega(sub 1), defining a blend time interval 2(tau)(sub 0) within which the global velocity of the robot manipulator is to be changed from a global target velocity v(sub 0) to the global transition velocity v(sub 1) and dividing the blend time interval 2(tau)(sub 0) into discrete time segments (delta)t. During each one of the discrete time segments delta t of the blend interval 2(tau)(sub 0), a blended global velocity v of the manipulator is computed as a blend of the global target velocity v(sub 0) and the global transition velocity v(sub 1), the blended global velocity v including a blended angular velocity omega and a blended linear velocity v, and then, the manipulator is rotated by an incremental rotation corresponding to an integration of the blended angular velocity omega over one discrete time segment (delta)t.

Fast linear feature detection using multiple directional non-maximum suppression.

PubMed

Sun, C; Vallotton, P

2009-05-01

The capacity to detect linear features is central to image analysis, computer vision and pattern recognition and has practical applications in areas such as neurite outgrowth detection, retinal vessel extraction, skin hair removal, plant root analysis and road detection. Linear feature detection often represents the starting point for image segmentation and image interpretation. In this paper, we present a new algorithm for linear feature detection using multiple directional non-maximum suppression with symmetry checking and gap linking. Given its low computational complexity, the algorithm is very fast. We show in several examples that it performs very well in terms of both sensitivity and continuity of detected linear features.

78 FR 62357 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-21

..., filing of petitions and applications and agency #0;statements of organization and functions are examples... interested in obtaining more information should contact Paul Kollmer-Dorsey at (202) 203-4545. Paul Kollmer...

Can segmentation evaluation metric be used as an indicator of land cover classification accuracy?

NASA Astrophysics Data System (ADS)

Švab Lenarčič, Andreja; Đurić, Nataša; Čotar, Klemen; Ritlop, Klemen; Oštir, Krištof

2016-10-01

It is a broadly established belief that the segmentation result significantly affects subsequent image classification accuracy. However, the actual correlation between the two has never been evaluated. Such an evaluation would be of considerable importance for any attempts to automate the object-based classification process, as it would reduce the amount of user intervention required to fine-tune the segmentation parameters. We conducted an assessment of segmentation and classification by analyzing 100 different segmentation parameter combinations, 3 classifiers, 5 land cover classes, 20 segmentation evaluation metrics, and 7 classification accuracy measures. The reliability definition of segmentation evaluation metrics as indicators of land cover classification accuracy was based on the linear correlation between the two. All unsupervised metrics that are not based on number of segments have a very strong correlation with all classification measures and are therefore reliable as indicators of land cover classification accuracy. On the other hand, correlation at supervised metrics is dependent on so many factors that it cannot be trusted as a reliable classification quality indicator. Algorithms for land cover classification studied in this paper are widely used; therefore, presented results are applicable to a wider area.

Keynote Address: When Breath Becomes Air-As Physician Becomes Patient.

PubMed

Kalanithi, Lucy; Wakelee, Heather; Carlson, Robert W

2017-05-01

As part of the NCCN 22nd Annual Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer Care, Lucy Kalanithi, MD, wife of now-deceased best-selling author Paul Kalanithi ( When Breath Becomes Air ), and Heather Wakelee, MD, Paul's oncologist, discussed-for the first time together in a public forum-Paul's experience of going from a neurosurgery resident to a patient with cancer with a terminal diagnosis. Robert Carlson, MD, moderated the discussion. Copyright © 2017 by the National Comprehensive Cancer Network.

25. Photocopy of aerial photograph dated May 1930; J. E. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. Photocopy of aerial photograph dated May 1930; J. E. Quigley, Photographer; original filed as MR2.9/SP8/p355 in Audio-visual Collection of Minnesota Historical Society, St. Paul; SHOWS RECENTLY COMPLETED NORTHWEST HANGAR AND ADMINISTRATION BUILDING I N UPPER LEFT (THREE-QUARTER VIEW OF WEST SIDE AND SOUTH FRONT); ALSO SHOWS THE SIMILARLY DESIGNED MUNICIPAL HANGAR UNDER CONSTRUCTION IN FOREGROUND; LOOKING NORTHEAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Proceedings of the Conference on the Design of Experiments in Army Research Development and Testing (34th) Held in Las Cruces, New Mexico on 19-21 October 1988

DTIC Science & Technology

1989-07-01

Webb and Linda L.C. Moss.............,,...,....., 27 COMPARISON OF RELIABILITY CONFIDENCE INTERVALS Paul H . Thrasher. ......... . 0 1...Webb and Linda L.C. Moss, U.S. Army Ballistic Research Laboratory COMPARISON OF RELIABILITY CONFIDENCE INTERVALS Paul H. Thrasher, White Sands Missile...RELEVANT Paul H. Thrasher, White Sands Missile Range 0930 - 1000 BREAK 1000 - 1130 GENERAL SESSION III Chairperson: Douglas B. Tang, Valter Reed Army

A Comparative Analysis of Army Physical Readiness Test Results of AMEDD Units Without Formal Physical Training Programs

DTIC Science & Technology

1984-06-01

Paul C.; Albrink , Margaret J.; and Krall, John M. "Exercise Effects on Fitness,, Lipids, Glucose Tolerance and Insulin Levels in Young Adults...1982): 14-15. Shepherd, Roy J.; Corey, Paul; Renzland, Peter; and Cox Michael . "The Impact of Changes in Fitness and Lifestyle Upon Health Care...Utilization." Canadian Journal of Public Health 74 (January/February 1983): 51-55. Shepherd, Roy J.; Corey, Paul; Renzland, Peter; and Cox, Michael . "The

Final Environmental Impact Statement. Ontonagon Harbor Operation and Maintenance Activities. Ontonagon County, Michigan.

DTIC Science & Technology

1975-08-01

Paul, Minnesota 55101 August 1975 ,.’U * - S • S S S S S • S U U FIN"L ENVIRONMENTAL IMPACT STATEMENT OPERATION AND MAINTENANCE ACTIVITIES ONTONAGON...HARBOR, MICHIGAN LAKE SUPERIOR Responsible Office: St. Paul District, Corps of Engineers, 1135 U.S. Post Office and Custom House, St. Paul, Minnesota ... mining is present at White Pine, 12 air miles southwest of Ontonagon Harbor. 6 2.130 Topography. - The area’s topography is directly related to the

Aerodynamic Optimization of a Supersonic Bending Body Projectile by a Vector-Evaluated Genetic Algorithm

DTIC Science & Technology

2016-12-01

Evaluated Genetic Algorithm prepared by Justin L Paul Academy of Applied Science 24 Warren Street Concord, NH 03301 under contract W911SR...Supersonic Bending Body Projectile by a Vector-Evaluated Genetic Algorithm prepared by Justin L Paul Academy of Applied Science 24 Warren Street... Genetic Algorithm 5a. CONTRACT NUMBER W199SR-15-2-001 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Justin L Paul 5d. PROJECT

STS 41-G crew prepares to leave Operations and checkout bldg for launch

NASA Image and Video Library

1984-10-05

41G-90081 / S17-90081 (5 Oct 1984) --- The seven member crew leaves the Operations and Checkout Building (OCB) to take a van ride to the launch pad. Leading the way is Kathryn D. Sullivan followed in file by Robert L. Crippen, Paul D. Scully-Power and Jon A. McBride. On the right side are Sally K. Ride, David C. Leestma and Marc Garneau. Trailing the crew are George W. S. Abbey, Richard Nygren, Paul Bulver, and Paul J. Weitz.

Paul D. Sturkie: Avian cardiac physiologist.

PubMed

Bello, Nicholas T; Cohick, Wendie S; McKeever, Kenneth H; Malinowski, Karyn

2018-06-01

Sturkie's Avian Physiology is a highly regarded textbook for the study of comparative poultry physiology. Less well known, however, is the contribution of Paul D. Sturkie (1909-2002) as a pioneer in the experimental physiology of avian species. His seminal research on the cardiovascular and hemodynamic controls of chickens and egg-laying hens had a notable impact on the poultry industry and breeding practices of farmers. The purpose of this article is to highlight the contributions and practical insights of Paul D. Sturkie to the field of poultry science.

Paul Oil Company, Inc. Consent Agreements and Proposed Final Orders

EPA Pesticide Factsheets

Proposed settlements, recorded in two Consent Agreements and Final Orders (“Proposed Consent Agreements”), between EPA and Paul Oil Company, Inc., to resolve two civil administrative penalty proceedings.

5. Historic American Buildings Survey Paul J. F. Schumacher, Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Paul J. F. Schumacher, Photographer September 1957 FRONT and WEST SIDE ELEVATIONS - Sacred Heart Mission, Interstate 90 & Interchange 39, Cataldo, Shoshone County, ID

Self-organising mixture autoregressive model for non-stationary time series modelling.

PubMed

Ni, He; Yin, Hujun

2008-12-01

Modelling non-stationary time series has been a difficult task for both parametric and nonparametric methods. One promising solution is to combine the flexibility of nonparametric models with the simplicity of parametric models. In this paper, the self-organising mixture autoregressive (SOMAR) network is adopted as a such mixture model. It breaks time series into underlying segments and at the same time fits local linear regressive models to the clusters of segments. In such a way, a global non-stationary time series is represented by a dynamic set of local linear regressive models. Neural gas is used for a more flexible structure of the mixture model. Furthermore, a new similarity measure has been introduced in the self-organising network to better quantify the similarity of time series segments. The network can be used naturally in modelling and forecasting non-stationary time series. Experiments on artificial, benchmark time series (e.g. Mackey-Glass) and real-world data (e.g. numbers of sunspots and Forex rates) are presented and the results show that the proposed SOMAR network is effective and superior to other similar approaches.

The E3 combustors: Status and challenges. [energy efficient turbofan engines

NASA Technical Reports Server (NTRS)

Sokolowski, D. E.; Rohde, J. E.

1981-01-01

The design, fabrication, and initial testing of energy efficient engine combustors, developed for the next generation of turbofan engines for commercial aircraft, are described. The combustor designs utilize an annular configuration with two zone combustion for low emissions, advanced liners for improved durability, and short, curved-wall, dump prediffusers for compactness. Advanced cooling techniques and segmented construction characterize the advanced liners. Linear segments are made from castable, turbine-type materials.

Featured Image: Tests of an MHD Code

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-09-01

Creating the codes that are used to numerically model astrophysical systems takes a lot of work and a lot of testing! A new, publicly available moving-mesh magnetohydrodynamics (MHD) code, DISCO, is designed to model 2D and 3D orbital fluid motion, such as that of astrophysical disks. In a recent article, DISCO creator Paul Duffell (University of California, Berkeley) presents the code and the outcomes from a series of standard tests of DISCOs stability, accuracy, and scalability.From left to right and top to bottom, the test outputs shown above are: a cylindrical Kelvin-Helmholtz flow (showing off DISCOs numerical grid in 2D), a passive scalar in a smooth vortex (can DISCO maintain contact discontinuities?), a global look at the cylindrical Kelvin-Helmholtz flow, a Jupiter-mass planet opening a gap in a viscous disk, an MHD flywheel (a test of DISCOs stability), an MHD explosion revealing shock structures, an MHD rotor (a more challenging version of the explosion), a Flock 3D MRI test (can DISCO study linear growth of the magnetorotational instability in disks?), and a nonlinear 3D MRI test.Check out the gif below for a closer look at each of these images, or follow the link to the original article to see even more!CitationPaul C. Duffell 2016 ApJS 226 2. doi:10.3847/0067-0049/226/1/2

The design of a linear L-band high power amplifier for mobile communication satellites

NASA Technical Reports Server (NTRS)

Whittaker, N.; Brassard, G.; Li, E.; Goux, P.

1990-01-01

A linear L-band solid state high power amplifier designed for the space segment of the Mobile Satellite (MSAT) mobile communication system is described. The amplifier is capable of producing 35 watts of RF power with multitone signal at an efficiency of 25 percent and with intermodulation products better than 16 dB below carrier.

Automatic control: the vertebral column of dogfish sharks behaves as a continuously variable transmission with smoothly shifting functions.

PubMed

Porter, Marianne E; Ewoldt, Randy H; Long, John H

2016-09-15

During swimming in dogfish sharks, Squalus acanthias, both the intervertebral joints and the vertebral centra undergo significant strain. To investigate this system, unique among vertebrates, we cyclically bent isolated segments of 10 vertebrae and nine joints. For the first time in the biomechanics of fish vertebral columns, we simultaneously characterized non-linear elasticity and viscosity throughout the bending oscillation, extending recently proposed techniques for large-amplitude oscillatory shear (LAOS) characterization to large-amplitude oscillatory bending (LAOB). The vertebral column segments behave as non-linear viscoelastic springs. Elastic properties dominate for all frequencies and curvatures tested, increasing as either variable increases. Non-linearities within a bending cycle are most in evidence at the highest frequency, 2.0 Hz, and curvature, 5 m -1 Viscous bending properties are greatest at low frequencies and high curvatures, with non-linear effects occurring at all frequencies and curvatures. The range of mechanical behaviors includes that of springs and brakes, with smooth transitions between them that allow for continuously variable power transmission by the vertebral column to assist in the mechanics of undulatory propulsion. © 2016. Published by The Company of Biologists Ltd.

Improved Speech Coding Based on Open-Loop Parameter Estimation

NASA Technical Reports Server (NTRS)

Juang, Jer-Nan; Chen, Ya-Chin; Longman, Richard W.

2000-01-01

A nonlinear optimization algorithm for linear predictive speech coding was developed early that not only optimizes the linear model coefficients for the open loop predictor, but does the optimization including the effects of quantization of the transmitted residual. It also simultaneously optimizes the quantization levels used for each speech segment. In this paper, we present an improved method for initialization of this nonlinear algorithm, and demonstrate substantial improvements in performance. In addition, the new procedure produces monotonically improving speech quality with increasing numbers of bits used in the transmitted error residual. Examples of speech encoding and decoding are given for 8 speech segments and signal to noise levels as high as 47 dB are produced. As in typical linear predictive coding, the optimization is done on the open loop speech analysis model. Here we demonstrate that minimizing the error of the closed loop speech reconstruction, instead of the simpler open loop optimization, is likely to produce negligible improvement in speech quality. The examples suggest that the algorithm here is close to giving the best performance obtainable from a linear model, for the chosen order with the chosen number of bits for the codebook.

Faults on Skylab imagery of the Salton Trough area, Southern California

NASA Technical Reports Server (NTRS)

Merifield, P. M.; Lamar, D. L. (Principal Investigator)

1975-01-01

The author has identified the following significant results. Large segments of the major high angle faults in the Salton Trough area are readily identifiable in Skylab images. Along active faults, distinctive topographic features such as scarps and offset drainage, and vegetation differences due to ground water blockage in alluvium are visible. Other fault-controlled features along inactive as well as active faults visible in Skylab photography include straight mountain fronts, linear valleys, and lithologic differences producing contrasting tone, color or texture. A northwestern extension of a fault in the San Andreas set, is postulated by the regional alignment of possible fault-controlled features. The suspected fault is covered by Holocene deposits, principally windblown sand. A northwest trending tonal change in cultivated fields across Mexicali Valley is visible on Skylab photos. Surface evidence for faulting was not observed; however, the linear may be caused by differences in soil conditions along an extension of a segment of the San Jacinto fault zone. No evidence of faulting could be found along linears which appear as possible extensions of the Substation and Victory Pass faults, demonstrating that the interpretation of linears as faults in small scale photography must be corroborated by field investigations.

High-Resolution Crystal Structures of Protein Helices Reconciled with Three-Centered Hydrogen Bonds and Multipole Electrostatics

PubMed Central

Kuster, Daniel J.; Liu, Chengyu; Fang, Zheng; Ponder, Jay W.; Marshall, Garland R.

2015-01-01

Theoretical and experimental evidence for non-linear hydrogen bonds in protein helices is ubiquitous. In particular, amide three-centered hydrogen bonds are common features of helices in high-resolution crystal structures of proteins. These high-resolution structures (1.0 to 1.5 Å nominal crystallographic resolution) position backbone atoms without significant bias from modeling constraints and identify Φ = -62°, ψ = -43 as the consensus backbone torsional angles of protein helices. These torsional angles preserve the atomic positions of α-β carbons of the classic Pauling α-helix while allowing the amide carbonyls to form bifurcated hydrogen bonds as first suggested by Némethy et al. in 1967. Molecular dynamics simulations of a capped 12-residue oligoalanine in water with AMOEBA (Atomic Multipole Optimized Energetics for Biomolecular Applications), a second-generation force field that includes multipole electrostatics and polarizability, reproduces the experimentally observed high-resolution helical conformation and correctly reorients the amide-bond carbonyls into bifurcated hydrogen bonds. This simple modification of backbone torsional angles reconciles experimental and theoretical views to provide a unified view of amide three-centered hydrogen bonds as crucial components of protein helices. The reason why they have been overlooked by structural biologists depends on the small crankshaft-like changes in orientation of the amide bond that allows maintenance of the overall helical parameters (helix pitch (p) and residues per turn (n)). The Pauling 3.613 α-helix fits the high-resolution experimental data with the minor exception of the amide-carbonyl electron density, but the previously associated backbone torsional angles (Φ, Ψ) needed slight modification to be reconciled with three-atom centered H-bonds and multipole electrostatics. Thus, a new standard helix, the 3.613/10-, Némethy- or N-helix, is proposed. Due to the use of constraints from monopole force fields and assumed secondary structures used in low-resolution refinement of electron density of proteins, such structures in the PDB often show linear hydrogen bonding. PMID:25894612

High-resolution crystal structures of protein helices reconciled with three-centered hydrogen bonds and multipole electrostatics.

PubMed

Kuster, Daniel J; Liu, Chengyu; Fang, Zheng; Ponder, Jay W; Marshall, Garland R

2015-01-01

Theoretical and experimental evidence for non-linear hydrogen bonds in protein helices is ubiquitous. In particular, amide three-centered hydrogen bonds are common features of helices in high-resolution crystal structures of proteins. These high-resolution structures (1.0 to 1.5 Å nominal crystallographic resolution) position backbone atoms without significant bias from modeling constraints and identify Φ = -62°, ψ = -43 as the consensus backbone torsional angles of protein helices. These torsional angles preserve the atomic positions of α-β carbons of the classic Pauling α-helix while allowing the amide carbonyls to form bifurcated hydrogen bonds as first suggested by Némethy et al. in 1967. Molecular dynamics simulations of a capped 12-residue oligoalanine in water with AMOEBA (Atomic Multipole Optimized Energetics for Biomolecular Applications), a second-generation force field that includes multipole electrostatics and polarizability, reproduces the experimentally observed high-resolution helical conformation and correctly reorients the amide-bond carbonyls into bifurcated hydrogen bonds. This simple modification of backbone torsional angles reconciles experimental and theoretical views to provide a unified view of amide three-centered hydrogen bonds as crucial components of protein helices. The reason why they have been overlooked by structural biologists depends on the small crankshaft-like changes in orientation of the amide bond that allows maintenance of the overall helical parameters (helix pitch (p) and residues per turn (n)). The Pauling 3.6(13) α-helix fits the high-resolution experimental data with the minor exception of the amide-carbonyl electron density, but the previously associated backbone torsional angles (Φ, Ψ) needed slight modification to be reconciled with three-atom centered H-bonds and multipole electrostatics. Thus, a new standard helix, the 3.6(13/10)-, Némethy- or N-helix, is proposed. Due to the use of constraints from monopole force fields and assumed secondary structures used in low-resolution refinement of electron density of proteins, such structures in the PDB often show linear hydrogen bonding.

Paul Lampe/McGarry Houghton | Division of Cancer Prevention

Cancer.gov

Project Title/Research Areas: Hybrid Plasma Markers that Complement CT Imaging for Early Lung Cancer DetectionPrincipal Investigator/Institution:  Paul Lampe/McGarry Houghton, Fred Hutchinson Cancer Research Center |

Paul Dirac

NASA Astrophysics Data System (ADS)

Pais, Abraham; Jacob, Maurice; Olive, David I.; Atiyah, Michael F.

2005-09-01

Preface Peter Goddard; Dirac memorial address Stephen Hawking; 1. Paul Dirac: aspects of his life and work Abraham Pais; 2. Antimatter Maurice Jacob; 3. The monopole David Olive; 4. The Dirac equation and geometry Michael F. Atiyah.

Paul Dirac

NASA Astrophysics Data System (ADS)

Pais, Abraham; Jacob, Maurice; Olive, David I.; Atiyah, Michael F.

1998-02-01

Preface Peter Goddard; Dirac memorial address Stephen Hawking; 1. Paul Dirac: aspects of his life and work Abraham Pais; 2. Antimatter Maurice Jacob; 3. The monopole David Olive; 4. The Dirac equation and geometry Michael F. Atiyah.

13. Photocopy of photograph mounted on Christmas card (from St. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopy of photograph mounted on Christmas card (from St. Paul's Church) Photographer unknown 1906 INTERIOR LOOKING EAST - St. Paul's Episcopal Church, 120 East J Street, Benicia, Solano County, CA

18. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL AREAS; LOOKING EAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

17. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL AREAS; LOOKING WEST. - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

ARC-2002-ACD02-0055-04

NASA Image and Video Library

2002-03-20

Sun-Earth Day WEBCAST - NASA TV; Host Paul Mortfield, Astronomer Stanford Solar Center and visiting students from San Francisco Bay Area Schools Documentation Technology Branch Video communications van (code-JIT) David Maurantonio, Paul Langston

Catalytic creativity. The case of Linus Pauling.

PubMed

Nakamura, J; Csikszentmihalyi, M

2001-04-01

This article illustrates how creativity is constituted by forces beyond the innovating individual, drawing examples from the career of the eminent chemist Linus Pauling. From a systems perspective, a scientific theory or other product is creative only if the innovation gains the acceptance of a field of experts and so transforms the culture. In addition to this crucial selective function vis-à-vis the completed work, the social field can play a catalytic role, fostering productive interactions between person and domain throughout a career. Pauling's case yields examples of how variously the social field contributes to creativity, shaping the individual's standards of judgment and providing opportunities, incentives, and critical evaluation. A formidable set of strengths suited Pauling for his scientific achievements, but examination of his career qualifies the notion of a lone genius whose brilliance carries the day.

Brotherly Advice: Letters from Hugo to Paul Ehrenfest in his Final Years

NASA Astrophysics Data System (ADS)

Halpern, Paul

2006-03-01

At the start of the 1930s, theoretician Paul Ehrenfest spent much of his time traveling through America and Europe while engaged in a steady stream of lectures. This traveling phase coincided with a frantic and intense period of negative self-examination, financial difficulty, and various other personal concerns that would ultimately lead to his 1933 suicide. Throughout these final years, he kept up a steady correspondence with his brother Hugo, a physician based in Saint Louis. Ten years older than Paul, Hugo freely doled out frank psychological advice about subjects ranging from the proper treatment of children to the dangers of self-pity. Through a look at some of the letters exchanged between the two brothers, this talk will examine the role Hugo played during the dark final years of Paul Ehrenfest's life.

The use of GIS for monitoring and predicting urban growth in east and west St Paul, Winnipeg, Manitoba, Canada.

PubMed

Hathout, S

2002-11-01

Most urban growth in Canada occurs in the urban-rural fringe. The increasing dispersal of the Canadian urban population is due to centrifugal forces pulling urbanites past the suburbs into the surrounding exurban communities. Most Canadian urban centres are located on prime agricultural land. Exurban sprawl devours an inordinate amount of the better agricultural land. The growth around the city of Winnipeg is a case in point. Within Winnipeg's urban field are the rural municipalities of East and West St Paul. The objective of this study is to investigate the impact of urban growth on the agricultural land of these RMs as well as the rate of urban growth in both Municipalities based on database analysis using aerial photographs taken in 1960 and 1989 and Geographic Information System (GIS). East St Paul was found to have a higher rate of urbanization (from 10.14% to 43.75%) between 1960 and 1989 than West St Paul (from 7.36% to 23.57%). The growth prediction using Markov probability chain analysis showed that East St Paul will henceforth experience a reduced rate of increase than West St Paul. The rate of urbanization for both RMs is found to be comparable with areas surrounding other major cities such as Toronto. The largest increases in urban land use categories occurred in and around the existing exurban settlements. It was found that most urbanization take place on the most fertile soil.

Comparative analysis of nonlinear dimensionality reduction techniques for breast MRI segmentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akhbardeh, Alireza; Jacobs, Michael A.; Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

2012-04-15

Purpose: Visualization of anatomical structures using radiological imaging methods is an important tool in medicine to differentiate normal from pathological tissue and can generate large amounts of data for a radiologist to read. Integrating these large data sets is difficult and time-consuming. A new approach uses both supervised and unsupervised advanced machine learning techniques to visualize and segment radiological data. This study describes the application of a novel hybrid scheme, based on combining wavelet transform and nonlinear dimensionality reduction (NLDR) methods, to breast magnetic resonance imaging (MRI) data using three well-established NLDR techniques, namely, ISOMAP, local linear embedding (LLE), andmore » diffusion maps (DfM), to perform a comparative performance analysis. Methods: Twenty-five breast lesion subjects were scanned using a 3T scanner. MRI sequences used were T1-weighted, T2-weighted, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) imaging. The hybrid scheme consisted of two steps: preprocessing and postprocessing of the data. The preprocessing step was applied for B{sub 1} inhomogeneity correction, image registration, and wavelet-based image compression to match and denoise the data. In the postprocessing step, MRI parameters were considered data dimensions and the NLDR-based hybrid approach was applied to integrate the MRI parameters into a single image, termed the embedded image. This was achieved by mapping all pixel intensities from the higher dimension to a lower dimensional (embedded) space. For validation, the authors compared the hybrid NLDR with linear methods of principal component analysis (PCA) and multidimensional scaling (MDS) using synthetic data. For the clinical application, the authors used breast MRI data, comparison was performed using the postcontrast DCE MRI image and evaluating the congruence of the segmented lesions. Results: The NLDR-based hybrid approach was able to define and segment both synthetic and clinical data. In the synthetic data, the authors demonstrated the performance of the NLDR method compared with conventional linear DR methods. The NLDR approach enabled successful segmentation of the structures, whereas, in most cases, PCA and MDS failed. The NLDR approach was able to segment different breast tissue types with a high accuracy and the embedded image of the breast MRI data demonstrated fuzzy boundaries between the different types of breast tissue, i.e., fatty, glandular, and tissue with lesions (>86%). Conclusions: The proposed hybrid NLDR methods were able to segment clinical breast data with a high accuracy and construct an embedded image that visualized the contribution of different radiological parameters.« less

Intervertebral disc response to cyclic loading--an animal model.

PubMed

Ekström, L; Kaigle, A; Hult, E; Holm, S; Rostedt, M; Hansson, T

1996-01-01

The viscoelastic response of a lumbar motion segment loaded in cyclic compression was studied in an in vivo porcine model (N = 7). Using surgical techniques, a miniaturized servohydraulic exciter was attached to the L2-L3 motion segment via pedicle fixation. A dynamic loading scheme was implemented, which consisted of one hour of sinusoidal vibration at 5 Hz, 50 N peak load, followed by one hour of restitution at zero load and one hour of sinusoidal vibration at 5 Hz, 100 N peak load. The force and displacement responses of the motion segment were sampled at 25 Hz. The experimental data were used for evaluating the parameters of two viscoelastic models: a standard linear solid model (three-parameter) and a linear Burger's fluid model (four-parameter). In this study, the creep behaviour under sinusoidal vibration at 5 Hz closely resembled the creep behaviour under static loading observed in previous studies. Expanding the three-parameter solid model into a four-parameter fluid model made it possible to separate out a progressive linear displacement term. This deformation was not fully recovered during restitution and is therefore an indication of a specific effect caused by the cyclic loading. High variability was observed in the parameters determined from the 50 N experimental data, particularly for the elastic modulus E1. However, at the 100 N load level, significant differences between the models were found. Both models accurately predicted the creep response under the first 800 s of 100 N loading, as displayed by mean absolute errors for the calculated deformation data from the experimental data of 1.26 and 0.97 percent for the solid and fluid models respectively. The linear Burger's fluid model, however, yielded superior predictions particularly for the initial elastic response.

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

PubMed Central

Yoshioka, Nayuta; Zangerl, Barbara; Nivison-Smith, Lisa; Khuu, Sieu K.; Jones, Bryan W.; Pfeiffer, Rebecca L.; Marc, Robert E.; Kalloniatis, Michael

2017-01-01

Purpose To characterize macular ganglion cell layer (GCL) changes with age and provide a framework to assess changes in ocular disease. This study used data clustering to analyze macular GCL patterns from optical coherence tomography (OCT) in a large cohort of subjects without ocular disease. Methods Single eyes of 201 patients evaluated at the Centre for Eye Health (Sydney, Australia) were retrospectively enrolled (age range, 20–85); 8 × 8 grid locations obtained from Spectralis OCT macular scans were analyzed with unsupervised classification into statistically separable classes sharing common GCL thickness and change with age. The resulting classes and gridwise data were fitted with linear and segmented linear regression curves. Additionally, normalized data were analyzed to determine regression as a percentage. Accuracy of each model was examined through comparison of predicted 50-year-old equivalent macular GCL thickness for the entire cohort to a true 50-year-old reference cohort. Results Pattern recognition clustered GCL thickness across the macula into five to eight spatially concentric classes. F-test demonstrated segmented linear regression to be the most appropriate model for macular GCL change. The pattern recognition–derived and normalized model revealed less difference between the predicted macular GCL thickness and the reference cohort (average ± SD 0.19 ± 0.92 and −0.30 ± 0.61 μm) than a gridwise model (average ± SD 0.62 ± 1.43 μm). Conclusions Pattern recognition successfully identified statistically separable macular areas that undergo a segmented linear reduction with age. This regression model better predicted macular GCL thickness. The various unique spatial patterns revealed by pattern recognition combined with core GCL thickness data provide a framework to analyze GCL loss in ocular disease. PMID:28632847

How Energy Efficiency is Adding Jobs in St. Paul, Minnesota

ScienceCinema

Hannigan, Jim; Coleman, Chris; Oliver, LeAnn; Jambois, Louis

2018-02-07

Saint Paul, Minnesota is using an energy efficiency grant to provide commercial retrofits that will allow a local produce distribution company to dramatically reduce its energy costs and add dozens of new workers.

Route-Specific Transit Marketing in Minneapolis/St. Paul, MN

DOT National Transportation Integrated Search

1985-10-01

The Minneapolis/St. Paul Transit Marketing Demonstration involved the administration of a combination of marketing techniques on five selected transit routes. The approach employed differed from most previous marketing demonstrations in that 1) prici...

JAFCO d/b/a Paul Davis Restoration and Remodeling Information Sheet

EPA Pesticide Factsheets

JAFCO d/b/a Paul Davis Restoration and Remodeling (the Company) is located in Memphis, Tennessee. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Memphis, Tennessee.

How Energy Efficiency is Adding Jobs in St. Paul, Minnesota

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hannigan, Jim; Coleman, Chris; Oliver, LeAnn

2011-01-01

Saint Paul, Minnesota is using an energy efficiency grant to provide commercial retrofits that will allow a local produce distribution company to dramatically reduce its energy costs and add dozens of new workers.

Update on Bayesian Blocks: Segmented Models for Sequential Data

NASA Technical Reports Server (NTRS)

Scargle, Jeff

2017-01-01

The Bayesian Block algorithm, in wide use in astronomy and other areas, has been improved in several ways. The model for block shape has been generalized to include other than constant signal rate - e.g., linear, exponential, or other parametric models. In addition the computational efficiency has been improved, so that instead of O(N**2) the basic algorithm is O(N) in most cases. Other improvements in the theory and application of segmented representations will be described.

Fast algorithm for automatically computing Strahler stream order

USGS Publications Warehouse

Lanfear, Kenneth J.

1990-01-01

An efficient algorithm was developed to determine Strahler stream order for segments of stream networks represented in a Geographic Information System (GIS). The algorithm correctly assigns Strahler stream order in topologically complex situations such as braided streams and multiple drainage outlets. Execution time varies nearly linearly with the number of stream segments in the network. This technique is expected to be particularly useful for studying the topology of dense stream networks derived from digital elevation model data.

NASA-Ames three-dimensional potential flow analysis system (POTFAN) equation solver code (SOLN) version 1

NASA Technical Reports Server (NTRS)

Davis, J. E.; Bonnett, W. S.; Medan, R. T.

1976-01-01

A computer program known as SOLN was developed as an independent segment of the NASA-Ames three-dimensional potential flow analysis systems of linear algebraic equations. Methods used include: LU decomposition, Householder's method, a partitioning scheme, and a block successive relaxation method. Due to the independent modular nature of the program, it may be used by itself and not necessarily in conjunction with other segments of the POTFAN system.

Dual-circuit segmented rail phased induction motor

DOEpatents

Marder, Barry M.; Cowan, Jr., Maynard

2002-01-01

An improved linear motor utilizes two circuits, rather that one circuit and an opposed plate, to gain efficiency. The powered circuit is a flat conductive coil. The opposed segmented rail circuit is either a plurality of similar conductive coils that are shorted, or a plurality of ladders formed of opposed conductive bars connected by a plurality of spaced conductors. In each embodiment, the conductors are preferably cables formed from a plurality of intertwined insulated wires to carry current evenly.

Modeling heading and path perception from optic flow in the case of independently moving objects

PubMed Central

Raudies, Florian; Neumann, Heiko

2013-01-01

Humans are usually accurate when estimating heading or path from optic flow, even in the presence of independently moving objects (IMOs) in an otherwise rigid scene. To invoke significant biases in perceived heading, IMOs have to be large and obscure the focus of expansion (FOE) in the image plane, which is the point of approach. For the estimation of path during curvilinear self-motion no significant biases were found in the presence of IMOs. What makes humans robust in their estimation of heading or path using optic flow? We derive analytical models of optic flow for linear and curvilinear self-motion using geometric scene models. Heading biases of a linear least squares method, which builds upon these analytical models, are large, larger than those reported for humans. This motivated us to study segmentation cues that are available from optic flow. We derive models of accretion/deletion, expansion/contraction, acceleration/deceleration, local spatial curvature, and local temporal curvature, to be used as cues to segment an IMO from the background. Integrating these segmentation cues into our method of estimating heading or path now explains human psychophysical data and extends, as well as unifies, previous investigations. Our analysis suggests that various cues available from optic flow help to segment IMOs and, thus, make humans' heading and path perception robust in the presence of such IMOs. PMID:23554589

Method for introducing unidirectional nested deletions

DOEpatents

Dunn, J.J.; Quesada, M.A.; Randesi, M.

1999-07-27

Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector. The cloning vector has an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe. 1 fig.

Method for introducing unidirectional nested deletions

DOEpatents

Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

1999-07-27

Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

Method for producing labeled single-stranded nucleic acid probes

DOEpatents

Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

1999-10-19

Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

Statistical Signal Models and Algorithms for Image Analysis

DTIC Science & Technology

1984-10-25

In this report, two-dimensional stochastic linear models are used in developing algorithms for image analysis such as classification, segmentation, and object detection in images characterized by textured backgrounds. These models generate two-dimensional random processes as outputs to which statistical inference procedures can naturally be applied. A common thread throughout our algorithms is the interpretation of the inference procedures in terms of linear prediction

Final Report: High Energy Physics Program (HEP), Physics Department, Princeton University

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callan, Curtis G.; Gubser, Steven S.; Marlow, Daniel R.

The activities of the Princeton Elementary particles group funded through Department of Energy Grant# DEFG02-91 ER40671 during the period October 1, 1991 through January 31, 2013 are summarized. These activities include experiments performed at Brookhaven National Lab; the CERN Lab in Geneva, Switzerland; Fermilab; KEK in Tsukuba City, Japan; the Stanford Linear Accelerator Center; as well as extensive experimental and the- oretical studies conducted on the campus of Princeton University. Funded senior personnel include: Curtis Callan, Stephen Gubser, Valerie Halyo, Daniel Marlow, Kirk McDonald, Pe- ter Meyers, James Olsen, Pierre Pirou e, Eric Prebys, A.J. Stewart Smith, Frank Shoemaker (deceased),more » Paul Steinhardt, David Stickland, Christopher Tully, and Liantao Wang.« less

Efficient and robust photo-ionization loading of beryllium ions

NASA Astrophysics Data System (ADS)

Wolf, Sebastian; Studer, Dominik; Wendt, Klaus; Schmidt-Kaler, Ferdinand

2018-02-01

We demonstrate the efficient generation of Be^+ ions with a 60 ns and 150 nJ laser pulse near 235 nm for two-step photo-ionization, proven by subsequent counting of the number of ions loaded into a linear Paul trap. The bandwidth and power of the laser pulse are chosen in such a way that a first, resonant step fully saturates the entire velocity distribution of beryllium atoms effusing from a thermal oven. The second excitation step is driven by the same light field causing efficient non-resonant ionization. Our ion-loading scheme has a similar efficiency as compared to former pathways using two-photon continuous wave laser excitation, but with an order of magnitude lower than average UV light power.

Decentralized control of large-scale systems: Fixed modes, sensitivity and parametric robustness. Ph.D. Thesis - Universite Paul Sabatier, 1985

NASA Technical Reports Server (NTRS)

Tarras, A.

1987-01-01

The problem of stabilization/pole placement under structural constraints of large scale linear systems is discussed. The existence of a solution to this problem is expressed in terms of fixed modes. The aim is to provide a bibliographic survey of the available results concerning the fixed modes (characterization, elimination, control structure selection to avoid them, control design in their absence) and to present the author's contribution to this problem which can be summarized by the use of the mode sensitivity concept to detect or to avoid them, the use of vibrational control to stabilize them, and the addition of parametric robustness considerations to design an optimal decentralized robust control.

11. Photocopy of 1906 photograph. Glass negative in Paul A. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopy of 1906 photograph. Glass negative in Paul A. Kohl's office, Missouri Botanical Garden. CLOSE VIEW OF LINNAEUS BUST - Missouri Botanical Garden, Linnaean House, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

76 FR 8656 - Safety Zone; Miami International Triathlon, Bayfront Park, Miami, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

...-mail Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A.Steiner@uscg.mil . If you have questions on viewing the docket, call Renee V...

Coastal Imaging Spectroscopy

DTIC Science & Technology

2006-09-30

Year, Semi-Finalist, Florida Environmental Research Institute, W. Paul Bissett, Ph.D., Executive Director, Greater Tampa Chamber of Commerce . 2004...Small Business of the Year, -Finalist, Florida Environmental Research Institute, W. Paul Bissett, Ph.D., Executive Director, Greater Tampa Chamber of Commerce .

Sun-Earth Day WEBCAST - NASA TV; Host Paul Mortfield, Astronomer Stanford Solar Center and visiting

NASA Technical Reports Server (NTRS)

2002-01-01

Sun-Earth Day WEBCAST - NASA TV; Host Paul Mortfield, Astronomer Stanford Solar Center and visiting students from San Francisco Bay Area Schools Documentation Technology Branch Video communications van (code-JIT)

Paul Hill d/b/a Alternative Energy Windows and Siding

EPA Pesticide Factsheets

Paul Hill d/b/a Alternative Energy Windows and Siding (the Company) is located in Concord, New Hampshire. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Concord, New Hampshire.

Senate Confirmation Hearing IG

NASA Image and Video Library

2009-10-14

Paul K. Martin, nominee for Inspector General for NASA, answers questions during his confirmation hearing in front of the Senate Committee on Commerce, Science and Transportation, Thursday, Oct. 15, 2009, on Capitol Hill in Washington. Photo Credit: (NASA/Paul E. Alers)

Black strings, low viscosity fluids, and violation of cosmic censorship.

PubMed

Lehner, Luis; Pretorius, Frans

2010-09-03

We describe the behavior of 5-dimensional black strings, subject to the Gregory-Laflamme instability. Beyond the linear level, the evolving strings exhibit a rich dynamics, where at intermediate stages the horizon can be described as a sequence of 3-dimensional spherical black holes joined by black string segments. These segments are themselves subject to a Gregory-Laflamme instability, resulting in a self-similar cascade, where ever-smaller satellite black holes form connected by ever-thinner string segments. This behavior is akin to satellite formation in low-viscosity fluid streams subject to the Rayleigh-Plateau instability. The simulation results imply that the string segments will reach zero radius in finite asymptotic time, whence the classical space-time terminates in a naked singularity. Since no fine-tuning is required to excite the instability, this constitutes a generic violation of cosmic censorship.

3D Multi-segment foot kinematics in children: A developmental study in typically developing boys.

PubMed

Deschamps, Kevin; Staes, Filip; Peerlinck, Kathelijne; Van Geet, Christel; Hermans, Cedric; Matricali, Giovanni Arnoldo; Lobet, Sebastien

2017-02-01

The relationship between age and 3D rotations objectivized with multisegment foot models has not been quantified until now. The purpose of this study was therefore to investigate the relationship between age and multi-segment foot kinematics in a cross-sectional database. Barefoot multi-segment foot kinematics of thirty two typically developing boys, aged 6-20 years, were captured with the Rizzoli Multi-segment Foot Model. One-dimensional statistical parametric mapping linear regression was used to examine the relationship between age and 3D inter-segment rotations of the dominant leg during the full gait cycle. Age was significantly correlated with sagittal plane kinematics of the midfoot and the calcaneus-metatarsus inter-segment angle (p<0.0125). Age was also correlated with the transverse plane kinematics of the calcaneus-metatarsus angle (p<0.0001). Gait labs should consider age related differences and variability if optimal decision making is pursued. It remains unclear if this is of interest for all foot models, however, the current study highlights that this is of particular relevance for foot models which incorporate a separate midfoot segment. Copyright © 2016 Elsevier B.V. All rights reserved.

Residential roof condition assessment system using deep learning

NASA Astrophysics Data System (ADS)

Wang, Fan; Kerekes, John P.; Xu, Zhuoyi; Wang, Yandong

2018-01-01

The emergence of high resolution (HR) and ultra high resolution (UHR) airborne remote sensing imagery is enabling humans to move beyond traditional land cover analysis applications to the detailed characterization of surface objects. A residential roof condition assessment method using techniques from deep learning is presented. The proposed method operates on individual roofs and divides the task into two stages: (1) roof segmentation, followed by (2) condition classification of the segmented roof regions. As the first step in this process, a self-tuning method is proposed to segment the images into small homogeneous areas. The segmentation is initialized with simple linear iterative clustering followed by deep learned feature extraction and region merging, with the optimal result selected by an unsupervised index, Q. After the segmentation, a pretrained residual network is fine-tuned on the augmented roof segments using a proposed k-pixel extension technique for classification. The effectiveness of the proposed algorithm was demonstrated on both HR and UHR imagery collected by EagleView over different study sites. The proposed algorithm has yielded promising results and has outperformed traditional machine learning methods using hand-crafted features.

Image segmentation with a novel regularized composite shape prior based on surrogate study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Tingting, E-mail: tingtingzhao@mednet.ucla.edu; Ruan, Dan, E-mail: druan@mednet.ucla.edu

Purpose: Incorporating training into image segmentation is a good approach to achieve additional robustness. This work aims to develop an effective strategy to utilize shape prior knowledge, so that the segmentation label evolution can be driven toward the desired global optimum. Methods: In the variational image segmentation framework, a regularization for the composite shape prior is designed to incorporate the geometric relevance of individual training data to the target, which is inferred by an image-based surrogate relevance metric. Specifically, this regularization is imposed on the linear weights of composite shapes and serves as a hyperprior. The overall problem is formulatedmore » in a unified optimization setting and a variational block-descent algorithm is derived. Results: The performance of the proposed scheme is assessed in both corpus callosum segmentation from an MR image set and clavicle segmentation based on CT images. The resulted shape composition provides a proper preference for the geometrically relevant training data. A paired Wilcoxon signed rank test demonstrates statistically significant improvement of image segmentation accuracy, when compared to multiatlas label fusion method and three other benchmark active contour schemes. Conclusions: This work has developed a novel composite shape prior regularization, which achieves superior segmentation performance than typical benchmark schemes.« less

A Segmentation Method for Lung Parenchyma Image Sequences Based on Superpixels and a Self-Generating Neural Forest

PubMed Central

Liao, Xiaolei; Zhao, Juanjuan; Jiao, Cheng; Lei, Lei; Qiang, Yan; Cui, Qiang

2016-01-01

Background Lung parenchyma segmentation is often performed as an important pre-processing step in the computer-aided diagnosis of lung nodules based on CT image sequences. However, existing lung parenchyma image segmentation methods cannot fully segment all lung parenchyma images and have a slow processing speed, particularly for images in the top and bottom of the lung and the images that contain lung nodules. Method Our proposed method first uses the position of the lung parenchyma image features to obtain lung parenchyma ROI image sequences. A gradient and sequential linear iterative clustering algorithm (GSLIC) for sequence image segmentation is then proposed to segment the ROI image sequences and obtain superpixel samples. The SGNF, which is optimized by a genetic algorithm (GA), is then utilized for superpixel clustering. Finally, the grey and geometric features of the superpixel samples are used to identify and segment all of the lung parenchyma image sequences. Results Our proposed method achieves higher segmentation precision and greater accuracy in less time. It has an average processing time of 42.21 seconds for each dataset and an average volume pixel overlap ratio of 92.22 ± 4.02% for four types of lung parenchyma image sequences. PMID:27532214

Associations between Family Adversity and Brain Volume in Adolescence: Manual vs. Automated Brain Segmentation Yields Different Results.

PubMed

Lyden, Hannah; Gimbel, Sarah I; Del Piero, Larissa; Tsai, A Bryna; Sachs, Matthew E; Kaplan, Jonas T; Margolin, Gayla; Saxbe, Darby

2016-01-01

Associations between brain structure and early adversity have been inconsistent in the literature. These inconsistencies may be partially due to methodological differences. Different methods of brain segmentation may produce different results, obscuring the relationship between early adversity and brain volume. Moreover, adolescence is a time of significant brain growth and certain brain areas have distinct rates of development, which may compromise the accuracy of automated segmentation approaches. In the current study, 23 adolescents participated in two waves of a longitudinal study. Family aggression was measured when the youths were 12 years old, and structural scans were acquired an average of 4 years later. Bilateral amygdalae and hippocampi were segmented using three different methods (manual tracing, FSL, and NeuroQuant). The segmentation estimates were compared, and linear regressions were run to assess the relationship between early family aggression exposure and all three volume segmentation estimates. Manual tracing results showed a positive relationship between family aggression and right amygdala volume, whereas FSL segmentation showed negative relationships between family aggression and both the left and right hippocampi. However, results indicate poor overlap between methods, and different associations were found between early family aggression exposure and brain volume depending on the segmentation method used.

Associations between Family Adversity and Brain Volume in Adolescence: Manual vs. Automated Brain Segmentation Yields Different Results

PubMed Central

Lyden, Hannah; Gimbel, Sarah I.; Del Piero, Larissa; Tsai, A. Bryna; Sachs, Matthew E.; Kaplan, Jonas T.; Margolin, Gayla; Saxbe, Darby

2016-01-01

Associations between brain structure and early adversity have been inconsistent in the literature. These inconsistencies may be partially due to methodological differences. Different methods of brain segmentation may produce different results, obscuring the relationship between early adversity and brain volume. Moreover, adolescence is a time of significant brain growth and certain brain areas have distinct rates of development, which may compromise the accuracy of automated segmentation approaches. In the current study, 23 adolescents participated in two waves of a longitudinal study. Family aggression was measured when the youths were 12 years old, and structural scans were acquired an average of 4 years later. Bilateral amygdalae and hippocampi were segmented using three different methods (manual tracing, FSL, and NeuroQuant). The segmentation estimates were compared, and linear regressions were run to assess the relationship between early family aggression exposure and all three volume segmentation estimates. Manual tracing results showed a positive relationship between family aggression and right amygdala volume, whereas FSL segmentation showed negative relationships between family aggression and both the left and right hippocampi. However, results indicate poor overlap between methods, and different associations were found between early family aggression exposure and brain volume depending on the segmentation method used. PMID:27656121

A Brownian dynamics program for the simulation of linear and circular DNA and other wormlike chain polyelectrolytes.

PubMed Central

Klenin, K; Merlitz, H; Langowski, J

1998-01-01

For the interpretation of solution structural and dynamic data of linear and circular DNA molecules in the kb range, and for the prediction of the effect of local structural changes on the global conformation of such DNAs, we have developed an efficient and easy way to set up a program based on a second-order explicit Brownian dynamics algorithm. The DNA is modeled by a chain of rigid segments interacting through harmonic spring potentials for bending, torsion, and stretching. The electrostatics are handled using precalculated energy tables for the interactions between DNA segments as a function of relative orientation and distance. Hydrodynamic interactions are treated using the Rotne-Prager tensor. While maintaining acceptable precision, the simulation can be accelerated by recalculating this tensor only once in a certain number of steps. PMID:9533691

Registration-based interpolation applied to cardiac MRI

NASA Astrophysics Data System (ADS)

Ólafsdóttir, Hildur; Pedersen, Henrik; Hansen, Michael S.; Lyksborg, Mark; Hansen, Mads Fogtmann; Darkner, Sune; Larsen, Rasmus

2010-03-01

Various approaches have been proposed for segmentation of cardiac MRI. An accurate segmentation of the myocardium and ventricles is essential to determine parameters of interest for the function of the heart, such as the ejection fraction. One problem with MRI is the poor resolution in one dimension. A 3D registration algorithm will typically use a trilinear interpolation of intensities to determine the intensity of a deformed template image. Due to the poor resolution across slices, such linear approximation is highly inaccurate since the assumption of smooth underlying intensities is violated. Registration-based interpolation is based on 2D registrations between adjacent slices and is independent of segmentations. Hence, rather than assuming smoothness in intensity, the assumption is that the anatomy is consistent across slices. The basis for the proposed approach is the set of 2D registrations between each pair of slices, both ways. The intensity of a new slice is then weighted by (i) the deformation functions and (ii) the intensities in the warped images. Unlike the approach by Penney et al. 2004, this approach takes into account deformation both ways, which gives more robustness where correspondence between slices is poor. We demonstrate the approach on a toy example and on a set of cardiac CINE MRI. Qualitative inspection reveals that the proposed approach provides a more convincing transition between slices than images obtained by linear interpolation. A quantitative validation reveals significantly lower reconstruction errors than both linear and registration-based interpolation based on one-way registrations.

High-Resolution Gamma-Ray Imaging Measurements Using Externally Segmented Germanium Detectors

NASA Technical Reports Server (NTRS)

Callas, J.; Mahoney, W.; Skelton, R.; Varnell, L.; Wheaton, W.

1994-01-01

Fully two-dimensional gamma-ray imaging with simultaneous high-resolution spectroscopy has been demonstrated using an externally segmented germanium sensor. The system employs a single high-purity coaxial detector with its outer electrode segmented into 5 distinct charge collection regions and a lead coded aperture with a uniformly redundant array (URA) pattern. A series of one-dimensional responses was collected around 511 keV while the system was rotated in steps through 180 degrees. A non-negative, linear least-squares algorithm was then employed to reconstruct a 2-dimensional image. Corrections for multiple scattering in the detector, and the finite distance of source and detector are made in the reconstruction process.

Crack Front Segmentation and Facet Coarsening in Mixed-Mode Fracture

NASA Astrophysics Data System (ADS)

Chen, Chih-Hung; Cambonie, Tristan; Lazarus, Veronique; Nicoli, Matteo; Pons, Antonio J.; Karma, Alain

2015-12-01

A planar crack generically segments into an array of "daughter cracks" shaped as tilted facets when loaded with both a tensile stress normal to the crack plane (mode I) and a shear stress parallel to the crack front (mode III). We investigate facet propagation and coarsening using in situ microscopy observations of fracture surfaces at different stages of quasistatic mixed-mode crack propagation and phase-field simulations. The results demonstrate that the bifurcation from propagating a planar to segmented crack front is strongly subcritical, reconciling previous theoretical predictions of linear stability analysis with experimental observations. They further show that facet coarsening is a self-similar process driven by a spatial period-doubling instability of facet arrays.

12. Photocopy of 1906 photograph. Glass negative in Paul A. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Photocopy of 1906 photograph. Glass negative in Paul A. Kohl's office, Missouri Botanical Garden. BUST OF ASA GRAY AT SOUTH ENTRANCE - Missouri Botanical Garden, Linnaean House, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

13. Photocopy of 1906 photograph. Glass negative in Paul A. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopy of 1906 photograph. Glass negative in Paul A. Kohl's office, Missouri Botanical Garden. BUST OF THOMAS NUTTALL AT SOUTH ENTRANCE - Missouri Botanical Garden, Linnaean House, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

RadNet Air Data From St. Paul, MN

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for St. Paul, MN from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

Meet EPA Ecologist Paul Mayer, Ph.D.

EPA Pesticide Factsheets

EPA ecologist Paul Mayer, Ph.D. works in EPA's Groundwater and Ecosystem Restoration division where he studies riparian zones (the area along rivers and streams where the habitats are influenced by both the land and water) and stream restoration

Revised Mulliken Electronegativities I. Calculation and Conversion to Pauling Units.

ERIC Educational Resources Information Center

Bratsch, Steven G.

1988-01-01

Discusses a revision and extension of the Mulliken electronegativity scale to consider 50 elements. Describes the calculation of valence-state promotion energies and Mulliken atomic electronegativities and the conversion of Mulliken electronegativities to Pauling units. (CW)

Publications - GMC 219 | Alaska Division of Geological & Geophysical

Science.gov Websites

Paul G. Benedum Nulato Unit #1 well Authors: Murphy, J.M. Publication Date: 1993 Publisher: Alaska , Apatite fission track data of cuttings (1,000-11,500') from the Paul G. Benedum Nulato Unit #1 well

Segmentation of thalamus from MR images via task-driven dictionary learning

NASA Astrophysics Data System (ADS)

Liu, Luoluo; Glaister, Jeffrey; Sun, Xiaoxia; Carass, Aaron; Tran, Trac D.; Prince, Jerry L.

2016-03-01

Automatic thalamus segmentation is useful to track changes in thalamic volume over time. In this work, we introduce a task-driven dictionary learning framework to find the optimal dictionary given a set of eleven features obtained from T1-weighted MRI and diffusion tensor imaging. In this dictionary learning framework, a linear classifier is designed concurrently to classify voxels as belonging to the thalamus or non-thalamus class. Morphological post-processing is applied to produce the final thalamus segmentation. Due to the uneven size of the training data samples for the non-thalamus and thalamus classes, a non-uniform sampling scheme is pro- posed to train the classifier to better discriminate between the two classes around the boundary of the thalamus. Experiments are conducted on data collected from 22 subjects with manually delineated ground truth. The experimental results are promising in terms of improvements in the Dice coefficient of the thalamus segmentation overstate-of-the-art atlas-based thalamus segmentation algorithms.

Differential and relaxed image foresting transform for graph-cut segmentation of multiple 3D objects.

PubMed

Moya, Nikolas; Falcão, Alexandre X; Ciesielski, Krzysztof C; Udupa, Jayaram K

2014-01-01

Graph-cut algorithms have been extensively investigated for interactive binary segmentation, when the simultaneous delineation of multiple objects can save considerable user's time. We present an algorithm (named DRIFT) for 3D multiple object segmentation based on seed voxels and Differential Image Foresting Transforms (DIFTs) with relaxation. DRIFT stands behind efficient implementations of some state-of-the-art methods. The user can add/remove markers (seed voxels) along a sequence of executions of the DRIFT algorithm to improve segmentation. Its first execution takes linear time with the image's size, while the subsequent executions for corrections take sublinear time in practice. At each execution, DRIFT first runs the DIFT algorithm, then it applies diffusion filtering to smooth boundaries between objects (and background) and, finally, it corrects possible objects' disconnection occurrences with respect to their seeds. We evaluate DRIFT in 3D CT-images of the thorax for segmenting the arterial system, esophagus, left pleural cavity, right pleural cavity, trachea and bronchi, and the venous system.

Hybrid active contour model for inhomogeneous image segmentation with background estimation

NASA Astrophysics Data System (ADS)

Sun, Kaiqiong; Li, Yaqin; Zeng, Shan; Wang, Jun

2018-03-01

This paper proposes a hybrid active contour model for inhomogeneous image segmentation. The data term of the energy function in the active contour consists of a global region fitting term in a difference image and a local region fitting term in the original image. The difference image is obtained by subtracting the background from the original image. The background image is dynamically estimated from a linear filtered result of the original image on the basis of the varying curve locations during the active contour evolution process. As in existing local models, fitting the image to local region information makes the proposed model robust against an inhomogeneous background and maintains the accuracy of the segmentation result. Furthermore, fitting the difference image to the global region information makes the proposed model robust against the initial contour location, unlike existing local models. Experimental results show that the proposed model can obtain improved segmentation results compared with related methods in terms of both segmentation accuracy and initial contour sensitivity.

Segmentation of Thalamus from MR images via Task-Driven Dictionary Learning.

PubMed

Liu, Luoluo; Glaister, Jeffrey; Sun, Xiaoxia; Carass, Aaron; Tran, Trac D; Prince, Jerry L

2016-02-27

Automatic thalamus segmentation is useful to track changes in thalamic volume over time. In this work, we introduce a task-driven dictionary learning framework to find the optimal dictionary given a set of eleven features obtained from T1-weighted MRI and diffusion tensor imaging. In this dictionary learning framework, a linear classifier is designed concurrently to classify voxels as belonging to the thalamus or non-thalamus class. Morphological post-processing is applied to produce the final thalamus segmentation. Due to the uneven size of the training data samples for the non-thalamus and thalamus classes, a non-uniform sampling scheme is proposed to train the classifier to better discriminate between the two classes around the boundary of the thalamus. Experiments are conducted on data collected from 22 subjects with manually delineated ground truth. The experimental results are promising in terms of improvements in the Dice coefficient of the thalamus segmentation over state-of-the-art atlas-based thalamus segmentation algorithms.

An automatic multi-atlas prostate segmentation in MRI using a multiscale representation and a label fusion strategy

NASA Astrophysics Data System (ADS)

Álvarez, Charlens; Martínez, Fabio; Romero, Eduardo

2015-01-01

The pelvic magnetic Resonance images (MRI) are used in Prostate cancer radiotherapy (RT), a process which is part of the radiation planning. Modern protocols require a manual delineation, a tedious and variable activity that may take about 20 minutes per patient, even for trained experts. That considerable time is an important work ow burden in most radiological services. Automatic or semi-automatic methods might improve the efficiency by decreasing the measure times while conserving the required accuracy. This work presents a fully automatic atlas- based segmentation strategy that selects the more similar templates for a new MRI using a robust multi-scale SURF analysis. Then a new segmentation is achieved by a linear combination of the selected templates, which are previously non-rigidly registered towards the new image. The proposed method shows reliable segmentations, obtaining an average DICE Coefficient of 79%, when comparing with the expert manual segmentation, under a leave-one-out scheme with the training database.

BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration

NASA Astrophysics Data System (ADS)

Gao, Mingyong; Lu, Paul; Lynam, Dan; Bednark, Bridget; Campana, W. Marie; Sakamoto, Jeff; Tuszynski, Mark

2016-12-01

Objective. We combined implantation of multi-channel templated agarose scaffolds with growth factor gene delivery to examine whether this combinatorial treatment can enhance peripheral axonal regeneration through long sciatic nerve gaps. Approach. 15 mm long scaffolds were templated into highly organized, strictly linear channels, mimicking the linear organization of natural nerves into fascicles of related function. Scaffolds were filled with syngeneic bone marrow stromal cells (MSCs) secreting the growth factor brain derived neurotrophic factor (BDNF), and lentiviral vectors expressing BDNF were injected into the sciatic nerve segment distal to the scaffold implantation site. Main results. Twelve weeks after injury, scaffolds supported highly linear regeneration of host axons across the 15 mm lesion gap. The incorporation of BDNF-secreting cells into scaffolds significantly increased axonal regeneration, and additional injection of viral vectors expressing BDNF into the distal segment of the transected nerve significantly enhanced axonal regeneration beyond the lesion. Significance. Combinatorial treatment with multichannel bioengineered scaffolds and distal growth factor delivery significantly improves peripheral nerve repair, rivaling the gold standard of autografts.

Solving systems of linear equations by GPU-based matrix factorization in a Science Ground Segment

NASA Astrophysics Data System (ADS)

Legendre, Maxime; Schmidt, Albrecht; Moussaoui, Saïd; Lammers, Uwe

2013-11-01

Recently, Graphics Cards have been used to offload scientific computations from traditional CPUs for greater efficiency. This paper investigates the adaptation of a real-world linear system solver, which plays a central role in the data processing of the Science Ground Segment of ESA's astrometric Gaia mission. The paper quantifies the resource trade-offs between traditional CPU implementations and modern CUDA based GPU implementations. It also analyses the impact on the pipeline architecture and system development. The investigation starts from both a selected baseline algorithm with a reference implementation and a traditional linear system solver and then explores various modifications to control flow and data layout to achieve higher resource efficiency. It turns out that with the current state of the art, the modifications impact non-technical system attributes. For example, the control flow of the original modified Cholesky transform is modified so that locality of the code and verifiability deteriorate. The maintainability of the system is affected as well. On the system level, users will have to deal with more complex configuration control and testing procedures.

Influence of chain topology on polymer crystallization: poly(ethylene oxide) (PEO) rings vs. linear chains.

PubMed

Zardalidis, George; Mars, Julian; Allgaier, Jürgen; Mezger, Markus; Richter, Dieter; Floudas, George

2016-10-04

The absence of entanglements, the more compact structure and the faster diffusion in melts of cyclic poly(ethylene oxide) (PEO) chains have consequences on their crystallization behavior at the lamellar and spherulitic length scales. Rings with molecular weight below the entanglement molecular weight (M < M e ), attain the equilibrium configuration composed from twice-folded chains with a lamellar periodicity that is half of the corresponding linear chains. Rings with M > M e undergo distinct step-like conformational changes to a crystalline lamellar with the equilibrium configuration. Rings melt from this configuration in the absence of crystal thickening in sharp contrast to linear chains. In general, rings more easily attain their extended equilibrium configuration due to strained segments and the absence of entanglements. In addition, rings have a higher equilibrium melting temperature. At the level of the spherulitic superstructure, growth rates are much faster for rings reflecting the faster diffusion and more compact structure. With respect to the segmental dynamics in their semi-crystalline state, ring PEOs with a steepness index of ∼34 form some of the "strongest" glasses.

Robust Neighboring Optimal Guidance for the Advanced Launch System

NASA Technical Reports Server (NTRS)

Hull, David G.

1993-01-01

In recent years, optimization has become an engineering tool through the availability of numerous successful nonlinear programming codes. Optimal control problems are converted into parameter optimization (nonlinear programming) problems by assuming the control to be piecewise linear, making the unknowns the nodes or junction points of the linear control segments. Once the optimal piecewise linear control (suboptimal) control is known, a guidance law for operating near the suboptimal path is the neighboring optimal piecewise linear control (neighboring suboptimal control). Research conducted under this grant has been directed toward the investigation of neighboring suboptimal control as a guidance scheme for an advanced launch system.

Ionene modified small polymeric beads

NASA Technical Reports Server (NTRS)

Rembaum, Alan (Inventor)

1977-01-01

Linear ionene polyquaternary cationic polymeric segments are bonded by means of the Menshutkin reaction (quaternization) to biocompatible, extremely small, porous particles containing halide or tertiary amine sites which are centers for attachment of the segments. The modified beads in the form of emulsions or suspensions offer a large, positively-charged surface area capable of irreversibly binding polyanions such as heparin, DNA, RNA or bile acids to remove them from solution or of reversibly binding monoanions such as penicillin, pesticides, sex attractants and the like for slow release from the suspension.

Hepatitis B Shots Are Recommended for All New Babies

MedlinePlus

... Centers for Disease Control and Prevention Saint Paul, Minnesota • 651-647-9009 • www. immunize. org • www. vaccineinformation. ... Centers for Disease Control and Prevention Saint Paul, Minnesota • 651-647-9009 • www.immunize.org • www.vaccineinformation. ...

79. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

79. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, ca. 1890, #741.) ALEXANDER RAMSEY HOUSE, ca. 1890 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

76. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

76. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1860. #22358.) UPPER LEVEE FROM CHESTNUT STREET, 1860 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

74. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

74. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1896. #35105.) FIRST ROBERT STREET BRIDGE, ca. 1896 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

Paul Carlson | Center for Cancer Research

Cancer.gov

Paul Carlson, Ph.D. March 28 Principal Investigator Laboratory of Mucosal Pathogens and Cellular Immunology Center for Biologics Evaluation and Research (CBER), FDA Topic:  "Research and Regulation of novel biologic products at the FDA's Center for Biologics Evaluation and Research"

St. Paul central corridor study : Pierce Butler industrial redevelopment parkway

DOT National Transportation Integrated Search

2003-07-01

At present, development in the St. Paul Central Corridor is occurring piecemeal and lacks an integrative vision. This study's aim was to devise design approaches that create a district which integrates light industrial job creation and retention with...

27. Photocopy of August 25, 1921 photograph by Paul A. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

27. Photocopy of August 25, 1921 photograph by Paul A. Kohl. Glass Negative Box IX, Tower Grove, Missouri Botanical Garden. ITALIAN GARDEN BY JOHN NOYES, LOOKING WEST - Missouri Botanical Garden, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

76 FR 29642 - Special Local Regulations; Miami Super Boat Grand Prix, Miami Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-23

... INFORMATION CONTACT: If you have questions on this rule, call or e-mail Lieutenant Paul A. Steiner, Sector Miami Prevention Department, Coast Guard; telephone 305-535-8724, e-mail Paul.A.Steiner@uscg.mil . If...

Rotating Saddle Paul Trap.

ERIC Educational Resources Information Center

Rueckner, Wolfgang; And Others

1995-01-01

Describes a demonstration in which a ball is placed in an unstable position on a saddle shape. The ball becomes stable when it is rotated above some threshold angular velocity. The demonstration is a mechanical analog of confining a particle in a "Paul Trap". (DDR)

77 FR 48497 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-14

...--Yes Michael Meehan--Yes Dennis Mulhaupt--Yes Dana Perino--Yes Tara Sonenshine--Yes Statements from... Maryjean Buhler, Chief Financial Officer Paul Kollmer-Dorsey, Deputy General Counsel and Board Secretary... CONTACT PERSON FOR MORE INFORMATION: Persons interested in obtaining more information should contact Paul...

STS-134 Tweetup

NASA Image and Video Library

2011-04-28

Heather Paul, a project engineer for Johnson Space Center, talks about space suit technology during the STS-134 Tweetup, Thursday, April 28, 2011, at Kennedy Space Center in Cape Canaveral, Fla. About 150 NASA Twitter followers attended the event. Photo Credit: (NASA/Paul E. Alers)

Minutes of the Explosives Safety Seminar (22nd) Held in Anaheim, California on 26-28 August 1986. Volume 1

DTIC Science & Technology

1986-08-01

105 Paul D. Smith and Theodore R. Crawford BL.AST VENTING FROM A (UIBICLE 119 Y. Kivity and S. Fellur PRESSURE/TEMPERATURE DECAY IN I11 EXPLOSION...EFFECTIVENESS OF TH 5-1300 CUBICLES ADDED TO EXISTING 201 BUILDINGS Paul M. LaHoudc DESKTOP COWffRS AND EXPLOSIVE SAFU 239 John M.Ftrritto OPTIMAL DESIGN OF...EXPLOSIVES saFwlY ON READINESS - THE 799 PRICE OF SAFETY " BG Paul L. Greenberg N) NAVAL ARMAMENT DEW FUR THE ROYAL MUMALIAN NAVY 805 Comm -W k-wroughs

Asymptotic solution of Fokker-Planck equation for plasma in Paul traps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shah, Kushal

2010-05-15

An exact analytic solution of the Vlasov equation for the plasma distribution in a Paul trap is known to be a Maxwellian and thus, immune to collisions under the assumption of infinitely fast relaxation [K. Shah and H. S. Ramachandran, Phys. Plasmas 15, 062303 (2008)]. In this paper, it is shown that even for a more realistic situation of finite time relaxation, solutions of the Fokker-Planck equation lead to an equilibrium solution of the form of a Maxwellian with oscillatory temperature. This shows that the rf heating observed in Paul traps cannot be caused due to collisional effects alone.

Diagnostic Interference: People’s Use of Information in Incomplete Bayesian World Problems

DTIC Science & Technology

1990-07-01

them was the one who did it. Stephen and Paul are 5 year old twins. One afternoon their mother hired a new babysitter so she could go out to do errands...Paul broke the lamp? _ Reliability. Stephen’s and Paul’s mother enjoys dressing them alike. Before she left, she had said to the babysitter " New ...complementarity); and it one already has a degree of belief p(H) in proposition H, and one is given new evidence E pertinent to the truth of H, one can use a

Headache classification and the Bible: Was St Paul's thorn in the flesh migraine?

PubMed

Göbel, H; Isler, H; Hasenfratz, H P

1995-06-01

The conversion of Saul to Paul was a major event in the history of Western culture. Compared with its impact, any medical comments may seem redundant, but they have kept their place in the literature for many centuries. The flashing light that caused Saul to fall is often explained as solar retinopathy or keratitis, a seizure, or even a hysterical fit. These interpretations propose either a trivial injury or disease that would interfere with mental health. Neither version is quite compatible with the dramatic dimension of the event and with Paul's later achievements and sufferings. In later years, Paul became a great manager, preacher and writer who was able to carry on under any kind of duress, though not without very painful reactions. He was suffering from bouts of unilateral headache, and also from a chronic eye condition which gave great trouble to his followers but did not cause lasting damage; the descriptions fulfil the criteria for migraine without aura of the 1988 Headache Classification. If the flashing light that caused Paul to fall down is interpreted as a visual migraine aura, with the additional symptoms of "not seeing" or photophobia and anorexia, it falls into place with his later history of migraine.

Interactive Tooth Separation from Dental Model Using Segmentation Field

PubMed Central

2016-01-01

Tooth segmentation on dental model is an essential step of computer-aided-design systems for orthodontic virtual treatment planning. However, fast and accurate identifying cutting boundary to separate teeth from dental model still remains a challenge, due to various geometrical shapes of teeth, complex tooth arrangements, different dental model qualities, and varying degrees of crowding problems. Most segmentation approaches presented before are not able to achieve a balance between fine segmentation results and simple operating procedures with less time consumption. In this article, we present a novel, effective and efficient framework that achieves tooth segmentation based on a segmentation field, which is solved by a linear system defined by a discrete Laplace-Beltrami operator with Dirichlet boundary conditions. A set of contour lines are sampled from the smooth scalar field, and candidate cutting boundaries can be detected from concave regions with large variations of field data. The sensitivity to concave seams of the segmentation field facilitates effective tooth partition, as well as avoids obtaining appropriate curvature threshold value, which is unreliable in some case. Our tooth segmentation algorithm is robust to dental models with low quality, as well as is effective to dental models with different levels of crowding problems. The experiments, including segmentation tests of varying dental models with different complexity, experiments on dental meshes with different modeling resolutions and surface noises and comparison between our method and the morphologic skeleton segmentation method are conducted, thus demonstrating the effectiveness of our method. PMID:27532266

Whole vertebral bone segmentation method with a statistical intensity-shape model based approach

NASA Astrophysics Data System (ADS)

Hanaoka, Shouhei; Fritscher, Karl; Schuler, Benedikt; Masutani, Yoshitaka; Hayashi, Naoto; Ohtomo, Kuni; Schubert, Rainer

2011-03-01

An automatic segmentation algorithm for the vertebrae in human body CT images is presented. Especially we focused on constructing and utilizing 4 different statistical intensity-shape combined models for the cervical, upper / lower thoracic and lumbar vertebrae, respectively. For this purpose, two previously reported methods were combined: a deformable model-based initial segmentation method and a statistical shape-intensity model-based precise segmentation method. The former is used as a pre-processing to detect the position and orientation of each vertebra, which determines the initial condition for the latter precise segmentation method. The precise segmentation method needs prior knowledge on both the intensities and the shapes of the objects. After PCA analysis of such shape-intensity expressions obtained from training image sets, vertebrae were parametrically modeled as a linear combination of the principal component vectors. The segmentation of each target vertebra was performed as fitting of this parametric model to the target image by maximum a posteriori estimation, combined with the geodesic active contour method. In the experimental result by using 10 cases, the initial segmentation was successful in 6 cases and only partially failed in 4 cases (2 in the cervical area and 2 in the lumbo-sacral). In the precise segmentation, the mean error distances were 2.078, 1.416, 0.777, 0.939 mm for cervical, upper and lower thoracic, lumbar spines, respectively. In conclusion, our automatic segmentation algorithm for the vertebrae in human body CT images showed a fair performance for cervical, thoracic and lumbar vertebrae.

A real-time visual inspection method of fastening bolts in freight car operation

NASA Astrophysics Data System (ADS)

Nan, Guo; Yao, JunEn

2015-10-01

A real-time inspection of the key components is necessary for ensuring safe operation of freight car. While traditional inspection depends on the trained human inspectors, which is time-consuming and lower efficient. With the development of machine vision, vision-based inspection methods get more railway on-spot applications. The cross rod end fastening bolts are important components on both sides of the train body that fixing locking plates together with the freight car main structure. In our experiment, we get the images containing fastening bolt components, and accurately locate the locking plate position using a linear Support Vector Machine (SVM) locating model trained with Histograms of Oriented Gradients (HOG) features. Then we extract the straight line segment using the Line Segment Detector (LSD) and encoding them in a range, which constitute a straight line segment dataset. Lastly we determine the locking plate's working state by the linear pattern. The experiment result shows that the localization accurate rate is over 99%, the fault detection rate is over 95%, and the module implementation time is 2f/s. The overall performance can completely meet the practical railway safety assurance application.

Photo-induced chemiluminometric determination of Karbutilate in a continuous-flow multicommutation assembly.

PubMed

Amorim, C M P G; Albert-García, J R; Montenegro, M C B S; Araújo, A N; Calatayud, J Martínez

2007-01-17

The present paper deals with the chemiluminescent determination of the herbicide Karbutilate on the basis of its previous photodegradation by using a low-pressure Hg lamp as UV source in a continuous-flow multicommutation assembly (a solenoid valves set). The pesticide solution was segmented by a solenoid valve and sequentially alternated with segments of the 0.001 mol l(-1) of NaOH solution, the suitable media for the formation of photo-fragments; then it passes through the photo-reactor and was lead to the flow-cell after being divided in small segments which were sequentially alternated with the oxidizing system; 2 x 10(-5) mol l(-1) of potassium permanganate in 0.2% pyrophosphoric acid. The studied calibration range, from 0.1 microg l(-1) to 65 mg l(-1), resulted in a linear behaviour over the range 20 microg l(-1)-20 mg l(-1) and fitting the linear equation: I=(1180+/-30)C+(15+/-5) with the correlation coefficient 0.9998. The limit of detection was 10 microg l(-1) and the sample throughput 17 h(-1). After testing the influence of a large series of potential interfering species, the method was applied to water and human urine samples.

Comparison of sequence of trunk and arm motions between short and long official distance groups in javelin throwing.

PubMed

Liu, Hui; Leigh, Steve; Yu, Bing

2014-03-01

The purpose of this study was to determine the effects of sequences of the trunk and arm angular motions on the performance of javelin throwing. In this study, 32 male and 30 female elite javelin throwers participated and were separated into a short official distance group or a long official distance group in each gender. Three-dimensional coordinates of 21 body landmarks and 3 marks on the javelin in the best trial were collected for each subject. Joint center linear velocities and selected trunk and arm segment and joint angles and angular velocities were calculated. The times of the initiations of the selected segment and joint angular motions and maximum angular velocities were determined. The sequences of the initiations of the selected segment and joint angular motions and maximum angular velocities were compared between short and long official distance groups and between genders. The results demonstrated that short and long official distance groups employed similar sequences of the trunk and arm motions. Male and female javelin throwers employed different sequences of the trunk and arm motions. The sequences of the trunk and arm motions were different from those of the maximal joint center linear velocities.

Brownian dynamics simulations of a flexible polymer chain which includes continuous resistance and multibody hydrodynamic interactions

NASA Astrophysics Data System (ADS)

Butler, Jason E.; Shaqfeh, Eric S. G.

2005-01-01

Using methods adapted from the simulation of suspension dynamics, we have developed a Brownian dynamics algorithm with multibody hydrodynamic interactions for simulating the dynamics of polymer molecules. The polymer molecule is modeled as a chain composed of a series of inextensible, rigid rods with constraints at each joint to ensure continuity of the chain. The linear and rotational velocities of each segment of the polymer chain are described by the slender-body theory of Batchelor [J. Fluid Mech. 44, 419 (1970)]. To include hydrodynamic interactions between the segments of the chain, the line distribution of forces on each segment is approximated by making a Legendre polynomial expansion of the disturbance velocity on the segment, where the first two terms of the expansion are retained in the calculation. Thus, the resulting linear force distribution is specified by a center of mass force, couple, and stresslet on each segment. This method for calculating the hydrodynamic interactions has been successfully used to simulate the dynamics of noncolloidal suspensions of rigid fibers [O. G. Harlen, R. R. Sundararajakumar, and D. L. Koch, J. Fluid Mech. 388, 355 (1999); J. E. Butler and E. S. G. Shaqfeh, J. Fluid Mech. 468, 204 (2002)]. The longest relaxation time and center of mass diffusivity are among the quantities calculated with the simulation technique. Comparisons are made for different levels of approximation of the hydrodynamic interactions, including multibody interactions, two-body interactions, and the "freely draining" case with no interactions. For the short polymer chains studied in this paper, the results indicate a difference in the apparent scaling of diffusivity with polymer length for the multibody versus two-body level of approximation for the hydrodynamic interactions.

Brownian dynamics simulations of a flexible polymer chain which includes continuous resistance and multibody hydrodynamic interactions.

PubMed

Butler, Jason E; Shaqfeh, Eric S G

2005-01-01

Using methods adapted from the simulation of suspension dynamics, we have developed a Brownian dynamics algorithm with multibody hydrodynamic interactions for simulating the dynamics of polymer molecules. The polymer molecule is modeled as a chain composed of a series of inextensible, rigid rods with constraints at each joint to ensure continuity of the chain. The linear and rotational velocities of each segment of the polymer chain are described by the slender-body theory of Batchelor [J. Fluid Mech. 44, 419 (1970)]. To include hydrodynamic interactions between the segments of the chain, the line distribution of forces on each segment is approximated by making a Legendre polynomial expansion of the disturbance velocity on the segment, where the first two terms of the expansion are retained in the calculation. Thus, the resulting linear force distribution is specified by a center of mass force, couple, and stresslet on each segment. This method for calculating the hydrodynamic interactions has been successfully used to simulate the dynamics of noncolloidal suspensions of rigid fibers [O. G. Harlen, R. R. Sundararajakumar, and D. L. Koch, J. Fluid Mech. 388, 355 (1999); J. E. Butler and E. S. G. Shaqfeh, J. Fluid Mech. 468, 204 (2002)]. The longest relaxation time and center of mass diffusivity are among the quantities calculated with the simulation technique. Comparisons are made for different levels of approximation of the hydrodynamic interactions, including multibody interactions, two-body interactions, and the "freely draining" case with no interactions. For the short polymer chains studied in this paper, the results indicate a difference in the apparent scaling of diffusivity with polymer length for the multibody versus two-body level of approximation for the hydrodynamic interactions. (c) 2005 American Institute of Physics.

GPU-based relative fuzzy connectedness image segmentation.

PubMed

Zhuge, Ying; Ciesielski, Krzysztof C; Udupa, Jayaram K; Miller, Robert W

2013-01-01

Recently, clinical radiological research and practice are becoming increasingly quantitative. Further, images continue to increase in size and volume. For quantitative radiology to become practical, it is crucial that image segmentation algorithms and their implementations are rapid and yield practical run time on very large data sets. The purpose of this paper is to present a parallel version of an algorithm that belongs to the family of fuzzy connectedness (FC) algorithms, to achieve an interactive speed for segmenting large medical image data sets. The most common FC segmentations, optimizing an [script-l](∞)-based energy, are known as relative fuzzy connectedness (RFC) and iterative relative fuzzy connectedness (IRFC). Both RFC and IRFC objects (of which IRFC contains RFC) can be found via linear time algorithms, linear with respect to the image size. The new algorithm, P-ORFC (for parallel optimal RFC), which is implemented by using NVIDIA's Compute Unified Device Architecture (CUDA) platform, considerably improves the computational speed of the above mentioned CPU based IRFC algorithm. Experiments based on four data sets of small, medium, large, and super data size, achieved speedup factors of 32.8×, 22.9×, 20.9×, and 17.5×, correspondingly, on the NVIDIA Tesla C1060 platform. Although the output of P-ORFC need not precisely match that of IRFC output, it is very close to it and, as the authors prove, always lies between the RFC and IRFC objects. A parallel version of a top-of-the-line algorithm in the family of FC has been developed on the NVIDIA GPUs. An interactive speed of segmentation has been achieved, even for the largest medical image data set. Such GPU implementations may play a crucial role in automatic anatomy recognition in clinical radiology.

GPU-based relative fuzzy connectedness image segmentation

PubMed Central

Zhuge, Ying; Ciesielski, Krzysztof C.; Udupa, Jayaram K.; Miller, Robert W.

2013-01-01

Purpose: Recently, clinical radiological research and practice are becoming increasingly quantitative. Further, images continue to increase in size and volume. For quantitative radiology to become practical, it is crucial that image segmentation algorithms and their implementations are rapid and yield practical run time on very large data sets. The purpose of this paper is to present a parallel version of an algorithm that belongs to the family of fuzzy connectedness (FC) algorithms, to achieve an interactive speed for segmenting large medical image data sets. Methods: The most common FC segmentations, optimizing an ℓ∞-based energy, are known as relative fuzzy connectedness (RFC) and iterative relative fuzzy connectedness (IRFC). Both RFC and IRFC objects (of which IRFC contains RFC) can be found via linear time algorithms, linear with respect to the image size. The new algorithm, P-ORFC (for parallel optimal RFC), which is implemented by using NVIDIA’s Compute Unified Device Architecture (CUDA) platform, considerably improves the computational speed of the above mentioned CPU based IRFC algorithm. Results: Experiments based on four data sets of small, medium, large, and super data size, achieved speedup factors of 32.8×, 22.9×, 20.9×, and 17.5×, correspondingly, on the NVIDIA Tesla C1060 platform. Although the output of P-ORFC need not precisely match that of IRFC output, it is very close to it and, as the authors prove, always lies between the RFC and IRFC objects. Conclusions: A parallel version of a top-of-the-line algorithm in the family of FC has been developed on the NVIDIA GPUs. An interactive speed of segmentation has been achieved, even for the largest medical image data set. Such GPU implementations may play a crucial role in automatic anatomy recognition in clinical radiology. PMID:23298094

Linear Cowden nevus: a new distinct epidermal nevus.

PubMed

Happle, Rudolf

2007-01-01

Within the group of epidermal nevi, a so far nameless disorder is described under the term "linear Cowden nevus". This non-organoid epidermal nevus is caused by loss of heterozygosity, occurring at an early developmental stage in an embryo with a germline PTEN mutation, giving rise to Cowden disease. Hence, linear Cowden nevus can be categorized as a characteristic feature of type 2 segmental Cowden disease. Until now, several authors had mistaken this epidermal nevus as a manifestation of Proteus syndrome. The concept of linear Cowden nevus implies that Proteus syndrome is by no means caused by PTEN mutations. As a clinical difference, linear Cowden nevus is markedly papillomatous and thick, whereas linear Proteus nevus tends to be rather flat. Moreover, the spectrum of possibly associated cutaneous or extracutaneous anomalies differs in the two types of nevi. In conclusion, linear Cowden nevus, that may also be called "linear PTEN nevus", represents a distinct clinicogenetic entity.

77. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

77. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1859. #377. Photographer: Illingworth.) LOWER LEVEE FROM JACKSON STREET, 1859 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

65. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

65. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1889. #37682.) VIEW TO NORTH, SHOWING SPAN NOS. 6-24, 1889 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

69. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

69. Photocopy of photograph (original print in the Minnesota Historical society, St. Paul, Minnesota, 1984. #32375.) VIEW TO WEST, SHOWING DAMAGED BRIDGE AFTER CYCLONE. 1904. - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

77 FR 20820 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... Trust, and Gloria Foley, all of Lovington, Illinois, and Paul Michael Hrvol, Jr. and Paul Michael Hrvol... Bancorp, Inc. and thereby indirectly control Hardware State Bank, both of Lovington, Illinois. Board of...

44. Photograph of original sketch by Paul Cloyd, Historical Architect, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

44. Photograph of original sketch by Paul Cloyd, Historical Architect, Denver Service Center, National Park Service, Denver, Colorado, dated March 1985. EVOLUTION OF GRAND CANYON WATER RECLAMATION PLANT AS IT STANDS TODAY. - Water Reclamation Plant, Grand Canyon, Coconino County, AZ

Physical and Biological Modes of Thought in the Chemistry of Linus Pauling

NASA Astrophysics Data System (ADS)

Nye, Mary Jo

No figure in modern chemistry better exemplifies than Linus Pauling (1901-1994) the intersections of the scientific disciplines of chemistry, physics, and biology nor the roles of physical and biological modes of thought in the 'central science' of chemistry.

1. Photocopy of photograph (original print #17 located in ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of photograph (original print #17 - located in Pope & Talbot Archives. Port Gamble, WA). Unknown Photographer, September 1906. View of St. Paul's Episcopal Church, facing southwest from Rainier Avenue. - St. Paul's Episcopal Church, Rainier Avenue, Port Gamble, Kitsap County, WA

28. Photocopy of August 25, 1921 photograph by Paul A, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. Photocopy of August 25, 1921 photograph by Paul A, Kohl. Glass Negative Box IX, Tower Grove, Missouri Botanical Garden. ITALIAN GARDEN AND FLORAL DISPLAY HOUSE, LOOKING NORTH - Missouri Botanical Garden, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

Insights into the crystal chemistry of Earth materials rendered by electron density distributions: Pauling's rules revisited

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gibbs, Gerald V.; Ross, Nancy L.; Cox, David F.

2014-05-20

Pauling's first two rules are examined in terms of the accumulation of the electron density between bonded pairs of atoms for a relatively large number of oxide and silicate crystals and siloxane molecules. The distribution of the electron density shows that the radius of the oxygen atom is not fixed, but that it actually decreases systematically from ~1.40 Å to ~ 0.65 Å as the polarizing power and the electronegativity of the bonded metal atoms increase and the distribution of the O atom is progressively polarized and contracted along the bond vectors by the impact of the bonded interactions. Themore » contractions result in an aspherical oxygen atom that displays as many different bonded “radii” as it has bonded interactions. The bonded radii for the metal atoms match the Shannon and Prewitt ionic radii for the more electropositive atoms like potassium and sodium, but they are systematically larger for the more electronegative atoms like aluminum, silicon and phosphorous. Pauling's first rule is based on the assumption that the radius of the oxide anion is fixed and that the radii of the cations are such that radius sum of the spherical oxide anion and a cation necessarily equals the separation between the cation-anion bonded pair with the coordination number of the cation being determined by the ratio of the radii of the cation and anion. In the case of the bonded radii, the sum of the bonded radii for the metal atoms and the oxide anion necessarily equals the bond lengths by virtue of the way that the bonded radii were determined in the partitioning of the electron density along the bond path into metal and O atom parts. But, the radius ratio for the O and M atoms is an unsatisfactory rule for determining the coordination number of the metal atom inasmuch as a bonded O atom is not, in general, spherical, and its size varies substantially along its bonded directions. But by counting the number of bond paths that radiate from a bonded atom, the coordination number of the atom is determined uniquely independent of the asphericity and sizes of the atom. A power law connection established between the bond lengths and bond strengths for crystals and molecules is mirrored by a comparable power law connection between bond length and the accumulation of the electron density between bonded pairs of atoms, a connection that is consistent with Pauling's electroneutrality postulate that the charges of the atoms in an oxide are negligibly small. The connection indicates that a one-to-one correspondence exists between the accumulation between a pair of bonded atoms and the Pauling bond strength for M-O bonded interaction for all atoms of the periodic table. The connection provides a common basis for understanding the success of the manifold applications that have been made with the bond valence theory model together with the modeling of crystal structures, chemical zoning, leaching and cation transport in batteries and the like. We believe that the wide spread applications of the model in mineralogy and material science owes much of its success to the direct connection between bond strength and the quantum mechanical observable, the electron density distribution. Comparable power law expressions established for the bonded interactions for both crystals and molecules support Pauling's assertion that his second rule has significance for molecules as well as for crystals. A simple expression is found that provides a one to one connection between the accumulation of the electron density between bonded M and O atoms and the Pauling bond strength for all M atoms of the periodic table with ~ 95 % of the variation of the bond strength being explained in terms of a linear dependence on the accumulated electron density. Compelling evidence is presented that supports the argument that the Si-O bonded interactions for tiny siloxane molecules and silicate crystals are chemically equivalent.« less

Non-Convex Sparse and Low-Rank Based Robust Subspace Segmentation for Data Mining.

PubMed

Cheng, Wenlong; Zhao, Mingbo; Xiong, Naixue; Chui, Kwok Tai

2017-07-15

Parsimony, including sparsity and low-rank, has shown great importance for data mining in social networks, particularly in tasks such as segmentation and recognition. Traditionally, such modeling approaches rely on an iterative algorithm that minimizes an objective function with convex l ₁-norm or nuclear norm constraints. However, the obtained results by convex optimization are usually suboptimal to solutions of original sparse or low-rank problems. In this paper, a novel robust subspace segmentation algorithm has been proposed by integrating l p -norm and Schatten p -norm constraints. Our so-obtained affinity graph can better capture local geometrical structure and the global information of the data. As a consequence, our algorithm is more generative, discriminative and robust. An efficient linearized alternating direction method is derived to realize our model. Extensive segmentation experiments are conducted on public datasets. The proposed algorithm is revealed to be more effective and robust compared to five existing algorithms.

Electric Power Distribution System Model Simplification Using Segment Substitution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reiman, Andrew P.; McDermott, Thomas E.; Akcakaya, Murat

Quasi-static time-series (QSTS) simulation is used to simulate the behavior of distribution systems over long periods of time (typically hours to years). The technique involves repeatedly solving the load-flow problem for a distribution system model and is useful for distributed energy resource (DER) planning. When a QSTS simulation has a small time step and a long duration, the computational burden of the simulation can be a barrier to integration into utility workflows. One way to relieve the computational burden is to simplify the system model. The segment substitution method of simplifying distribution system models introduced in this paper offers modelmore » bus reduction of up to 98% with a simplification error as low as 0.2% (0.002 pu voltage). In contrast to existing methods of distribution system model simplification, which rely on topological inspection and linearization, the segment substitution method uses black-box segment data and an assumed simplified topology.« less

Structural Segmentation of Toru Takemitsu's Piece, Itinerant, by Advanced Level Music Graduate Students.

PubMed

Ordoñana, Jose A; Laucirica, Ana

2017-01-01

This work attempts to study the way higher music graduate students segment a contemporary music work, Itinerant, and to understand the influence of musical feature on segmentation. It attempts to test the theory stating that saliences contribute to organising the music surface. The 42 students listened to the work several times and, in real time, they were requested to indicate the places on the score where they perceived structural boundaries. This work is characterised by its linearity, which could hinder identification of saliences and thereby, the establishment of structural boundaries. The participants show stability in the points of segmentation chosen. The results show significant coincidences among the participants in strategic places of the work, which leads us to conclude, in line with other researches, although in a work with different characteristics, that listeners can find a structural organisation in contemporary music that could allow them to understand it.

Engineering single-polymer micelle shape using nonuniform spontaneous surface curvature

NASA Astrophysics Data System (ADS)

Moths, Brian; Witten, T. A.

2018-03-01

Conventional micelles, composed of simple amphiphiles, exhibit only a few standard morphologies, each characterized by its mean surface curvature set by the amphiphiles. Here we demonstrate a rational design scheme to construct micelles of more general shape from polymeric amphiphiles. We replace the many amphiphiles of a conventional micelle by a single flexible, linear, block copolymer chain containing two incompatible species arranged in multiple alternating segments. With suitable segment lengths, the chain exhibits a condensed spherical configuration in solution, similar to conventional micelles. Our design scheme posits that further shapes are attained by altering the segment lengths. As a first study of the power of this scheme, we demonstrate the capacity to produce long-lived micelles of horseshoe form using conventional bead-spring simulations in two dimensions. Modest changes in the segment lengths produce smooth changes in the micelle's shape and stability.

Automated segmentation of ventricles from serial brain MRI for the quantification of volumetric changes associated with communicating hydrocephalus in patients with brain tumor

NASA Astrophysics Data System (ADS)

Pura, John A.; Hamilton, Allison M.; Vargish, Geoffrey A.; Butman, John A.; Linguraru, Marius George

2011-03-01

Accurate ventricle volume estimates could improve the understanding and diagnosis of postoperative communicating hydrocephalus. For this category of patients, associated changes in ventricle volume can be difficult to identify, particularly over short time intervals. We present an automated segmentation algorithm that evaluates ventricle size from serial brain MRI examination. The technique combines serial T1- weighted images to increase SNR and segments the means image to generate a ventricle template. After pre-processing, the segmentation is initiated by a fuzzy c-means clustering algorithm to find the seeds used in a combination of fast marching methods and geodesic active contours. Finally, the ventricle template is propagated onto the serial data via non-linear registration. Serial volume estimates were obtained in an automated robust and accurate manner from difficult data.

Statistical Inference in Hidden Markov Models Using k-Segment Constraints

PubMed Central

Titsias, Michalis K.; Holmes, Christopher C.; Yau, Christopher

2016-01-01

Hidden Markov models (HMMs) are one of the most widely used statistical methods for analyzing sequence data. However, the reporting of output from HMMs has largely been restricted to the presentation of the most-probable (MAP) hidden state sequence, found via the Viterbi algorithm, or the sequence of most probable marginals using the forward–backward algorithm. In this article, we expand the amount of information we could obtain from the posterior distribution of an HMM by introducing linear-time dynamic programming recursions that, conditional on a user-specified constraint in the number of segments, allow us to (i) find MAP sequences, (ii) compute posterior probabilities, and (iii) simulate sample paths. We collectively call these recursions k-segment algorithms and illustrate their utility using simulated and real examples. We also highlight the prospective and retrospective use of k-segment constraints for fitting HMMs or exploring existing model fits. Supplementary materials for this article are available online. PMID:27226674

Dynamic multi-segmental postural control in patients with chronic non-specific low back pain compared to pain-free controls: A cross-sectional study.

PubMed

McCaskey, Michael A; Wirth, Brigitte; Schuster-Amft, Corina; de Bruin, Eling D

2018-01-01

Reduced postural control is thought to contribute to the development and persistence of chronic non-specific low back pain (CNLBP). It is therefore frequently assessed in affected patients and commonly reported as the average amount of postural sway while standing upright under a variety of sensory conditions. These averaged linear outcomes, such as mean centre of pressure (CP) displacement or mean CP surface areas, may not reflect the true postural status. Adding nonlinear outcomes and multi-segmental kinematic analysis has been reported to better reflect the complexity of postural control and may detect subtler postural differences. In this cross-sectional study, a combination of linear and nonlinear postural parameters were assessed in patients with CNLBP (n = 24, 24-75 years, 9 females) and compared to symptom-free controls (CG, n = 34, 22-67 years, 11 females). Primary outcome was postural control measured by variance of joint configurations (uncontrolled manifold index, UI), confidence ellipse surface areas (CEA) and approximate entropy (ApEn) of CP dispersion during the response phase of a perturbed postural control task on a swaying platform. Secondary outcomes were segment excursions and clinical outcome correlates for pain and function. Non-parametric tests for group comparison with P-adjustment for multiple comparisons were conducted. Principal component analysis was applied to identify patterns of segmental contribution in both groups. CNLBP and CG performed similarly with respect to the primary outcomes. Comparison of joint kinematics revealed significant differences of hip (P < .001) and neck (P < .025) angular excursion, representing medium to large group effects (r's = .36 - .51). Significant (P's < .05), but moderate correlations of ApEn (r = -.42) and UI (r = -.46) with the health-related outcomes were observed. These findings lend further support to the notion that averaged linear outcomes do not suffice to describe subtle postural differences in CNLBP patients with low to moderate pain status.

Recent Developments in Microwave Ion Clocks

NASA Astrophysics Data System (ADS)

Prestage, John D.; Tjoelker, Robert L.; Maleki, Lute

We review the development of microwave-frequency standards based on trapped ions. Following two distinct paths, microwave ion clocks have evolved greatly in the last twenty years since the earliest Paul-trap-based units. Laser-cooled ion frequency standards reduce the second-order Doppler shift from ion micromotion and thermal secular motion achieving good signal-to-noise ratios via cycling transitions where as many as ~10^8 photons per second per ion may be scattered. Today, laser-cooled ion standards are based on linear Paul traps which hold ions near the node line of the trapping electric field, minimizing micromotion at the trapping-field frequency and the consequent second-order Doppler frequency shift. These quadrupole (radial) field traps tightly confine tens of ions to a crystalline single-line structure. As more ions are trapped, space charge forces some ions away from the node-line axis and the second-order Doppler effect grows larger, even at negligibly small secular temperatures. Buffer-gas-cooled clocks rely on large numbers of ions, typically ~10^7, optically pumped by a discharge lamp at a scattering rate of a few photons per second per ion. To reduce the second-order Doppler shift from space charge repulsion of ions from the trap node line, novel multipole ion traps are now being developed where ions are weakly bound with confining fields that are effectively zero through the trap interior and grow rapidly near the trap electrode ``walls''.

Locomotor variation and bending regimes of capuchin limb bones.

PubMed

Demes, Brigitte; Carlson, Kristian J

2009-08-01

Primates are very versatile in their modes of progression, yet laboratory studies typically capture only a small segment of this variation. In vivo bone strain studies in particular have been commonly constrained to linear locomotion on flat substrates, conveying the potentially biased impression of stereotypic long bone loading patterns. We here present substrate reaction forces (SRF) and limb postures for capuchin monkeys moving on a flat substrate ("terrestrial"), on an elevated pole ("arboreal"), and performing turns. The angle between the SRF vector and longitudinal axes of the forearm or leg is taken as a proxy for the bending moment experienced by these limb segments. In both frontal and sagittal planes, SRF vectors and distal limb segments are not aligned, but form discrepant angles; that is, forces act on lever arms and exert bending moments. The positions of the SRF vectors suggest bending around oblique axes of these limb segments. Overall, the leg is exposed to greater moments than the forearm. Simulated arboreal locomotion and turns introduce variation in the discrepancy angles, thus confirming that expanding the range of locomotor behaviors studied will reveal variation in long bone loading patterns that is likely characteristic of natural locomotor repertoires. "Arboreal" locomotion, even on a linear noncompliant branch, is characterized by greater variability of force directions and discrepancy angles than "terrestrial" locomotion (significant for the forearm only), partially confirming the notion that life in trees is associated with greater variation in long bone loading. Directional changes broaden the range of external bending moments even further.

Determination of the herbicide benfuresate by its photo-induced chemiluminescence using flow multicommutation methodology.

PubMed

Albert-García, J R; Calatayud, J Martínez

2008-05-15

The present paper deals with an analytical strategy based on coupling photo-induced chemiluminescence in a multicommutation continuous-flow methodology for the determination of the herbicide benfuresate. The solenoid valve inserted as small segments of the analyte solution was sequentially alternated with segments of the NaOH solution for adjusting the medium for the photodegradation. Both flow rates (sample and medium) were adjusted to required time for photodegradation, 90 s; and then, the resulting solution was also sequentially inserted as segments alternated with segments of the oxidizing solution system, hexacyanoferrate (III) in alkaline medium. The calibration range from 1 microg L(-1) to 95 mg L(-1), resulted in a linear behaviour over the range 1 microg L(-1) to 4 mg L(-1) and fitting the linear equation: I=4555.7x+284.2, correlation coefficient 0.9999. The limit of detection was 0.1 microg L(-1) (n=5, criteria 3 sigma) and the sample throughput was 22 h(-1). The consumption of solutions was very small; per peak were 0.66 mL, 0.16 mL and 0. 32 mL sample, medium and oxidant, respectively. Inter- and intra-day reproducibility resulted in a R.S.D. of 3.9% and 3.4%, respectively. After testing the influence of a large series of potential interferents the method is applied to water samples obtained from different places, human urine and to one formulation.

Buckling Design and Analysis of a Payload Fairing One-Sixth Cylindrical Arc-Segment Panel

NASA Technical Reports Server (NTRS)

Kosareo, Daniel N.; Oliver, Stanley T.; Bednarcyk, Brett A.

2013-01-01

Design and analysis results are reported for a panel that is a 16th arc-segment of a full 33-ft diameter cylindrical barrel section of a payload fairing structure. Six such panels could be used to construct the fairing barrel, and, as such, compression buckling testing of a 16th arc-segment panel would serve as a validation test of the buckling analyses used to design the fairing panels. In this report, linear and nonlinear buckling analyses have been performed using finite element software for 16th arc-segment panels composed of aluminum honeycomb core with graphiteepoxy composite facesheets and an alternative fiber reinforced foam (FRF) composite sandwich design. The cross sections of both concepts were sized to represent realistic Space Launch Systems (SLS) Payload Fairing panels. Based on shell-based linear buckling analyses, smaller, more manageable buckling test panel dimensions were determined such that the panel would still be expected to buckle with a circumferential (as opposed to column-like) mode with significant separation between the first and second buckling modes. More detailed nonlinear buckling analyses were then conducted for honeycomb panels of various sizes using both Abaqus and ANSYS finite element codes, and for the smaller size panel, a solid-based finite element analysis was conducted. Finally, for the smaller size FRF panel, nonlinear buckling analysis was performed wherein geometric imperfections measured from an actual manufactured FRF were included. It was found that the measured imperfection did not significantly affect the panel's predicted buckling response

73. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

73. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1867. #MR2.9 SP4.2/rll.) FIRST WABASHA STREET BRIDGE, 1867 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

66. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

66. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, ca. 1925. #19657.) VIEW TO NORTHWEST, SHOWING SPAN NOS. 21 TO 26 - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

75 FR 38770 - Siskiyou, OR Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

.... Written comments should be sent to Paul Galloway, Medford Interagency Office, 3040 Biddle Road, Medford... facilitate entry into the building. FOR FURTHER INFORMATION CONTACT: Paul Galloway, Acting Public Affairs... the opportunity to address the Committee during that session. Dated: June 24, 2010. Scott D. Conroy...

Parallel Narrative Structure in Paul Harding's "Tinkers"

ERIC Educational Resources Information Center

Çirakli, Mustafa Zeki

2014-01-01

The present paper explores the implications of parallel narrative structure in Paul Harding's "Tinkers" (2009). Besides primarily recounting the two sets of parallel narratives, "Tinkers" also comprises of seemingly unrelated fragments such as excerpts from clock repair manuals and diaries. The main stories, however, told…

Line Designs Inspired by Paul Klee

ERIC Educational Resources Information Center

Blanchette, Lisa

2009-01-01

In this lesson, students learn about line, shape, color, mixed media and abstraction, while being introduced to Swiss artist, Paul Klee (1879-1940). This lesson works well with a variety of age levels and abilities and could also be used to teach analogous or triad color schemes.

Electron Microscopy of Tungsten Disulphide Inorganic Nanomaterials

DTIC Science & Technology

2009-09-01

cylindrical molecule similar to a carbon nanotube. Inorganic nanotubes have been observed in some mineral deposits. Linus Pauling suggested the...diffraction pattern was due to the carbon coating. Figure 6 SAED taken from the single nanotube shown in figure 5 REFERENCES 1. Pauling , L; "The

View of the PAVE PAWS radar from approach along Spencer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of the PAVE PAWS radar from approach along Spencer Paul Road, looking northwest - Beale Air Force Base, Perimeter Acquisition Vehicle Entry Phased-Array Warning System, End of Spencer Paul Road, north of Warren Shingle Road (14th Street), Marysville, Yuba County, CA

Predicting Upwelling Radiance on the West Florida Shelf

DTIC Science & Technology

2005-09-30

Business of the Year, Florida Environmental Research Institute, W. Paul Bissett, Ph.D., Executive Director, Greater Tampa Chamber of Commerce . Finalist...2004 Small Business of the Year, Florida Environmental Research Institute, W. Paul Bissett, Ph.D., Executive Director, Greater Tampa Chamber of Commerce . 9

In Memoriam: Paul J. Lioy

EPA Science Inventory

Exposure Science has lost one of its founders and intellectual champions. Dr. Paul Lioy unexpectedly passed away on July 8, 2015 at the age of 68 years. The world has been left a far better place thanks to Dr. Lioy’s vision and creativity, enormous scientific contributions,...

Colloquy to Paul Musset

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2007-12-13

En honneur de Paul Musset il a été décidé de faire plutôt un colloque scientifique à la place d'une cérémonie. Plusieurs personnes temoignent de leurs estime et amitié pour ce physicien et ses activités

76 FR 1532 - Determinations of Attainment by the Applicable Attainment Date for the Hayden, Nogales, Paul Spur...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-11

... indicated that we plan to address the PM 10 needs for Nogales and Paul Spur/Douglas areas over the next few... certain columns and rows and thereby causes a mismatch between concentrations and the corresponding years...

SEDIMENT DATA - ST. PAUL WATERWAY - TACOMA, WA - 1996 MONITORING DATA

EPA Science Inventory

Benthic Infauna Monitoring Data Files are Excel-format spreadsheet files which contain data presented in the St. Paul Waterway Area Remedial Action and Habitat Restoration Project, 1996 Monitoring Report. The files can be viewed directly or readily downlo aded and read into most ...

Historical review: another 50th anniversary--new periodicities in coiled coils.

PubMed

Gruber, Markus; Lupas, Andrei N

2003-12-01

In 1953, Francis Crick and Linus Pauling both proposed models of supercoiled alpha helices ('coiled coils') for the structure of keratin. These were the first attempts at modelling the tertiary structure of a protein. Crick emphasized the packing mode of the side-chains ('knobs-into-holes'), which required a periodicity of seven residues over two helical turns (7/2) and a supercoil in the opposite sense of the constituent helices. By contrast, Pauling envisaged a broader set of periodicities (4/1, 7/2, 18/5, 15/4, 11/3) and supercoils of both senses. Crick's model became canonical and the 'heptad repeat' essentially synonymous with coiled coils, but 50 years later new crystal structures and protein sequences show that the less common periodicities envisaged by Pauling also occur in coiled coils, adding a variant packing mode ('knobs-to-knobs') to the standard model. Pauling's laboratory notebooks suggest that he searched unsuccessfully for this packing mode in 1953.

Linus Pauling's "molecular diseases": between history and memory.

PubMed

Strasser, Bruno J

2002-08-30

In 1949, Linus Pauling and his collaborators published a study in the journal Science entitled "Sickle Cell Anemia, a Molecular Disease." In this now classic study, they showed that hemoglobin from patients suffering from sickle cell anemia has a different electrical charge than hemoglobin from healthy individuals. This result demonstrated for the first time that an abnormal protein could be causally linked to a disease, and that genes determined the structure of proteins. This report made headline news and had a powerful impact on both the biomedical community and the general public. Fifty years later, this study is discussed in almost every medical and biological textbook and has became a favorite example in editorials to illustrate the progress of biomedical research. This article explores the history of Pauling's sickle cell anemia and its subsequent integration in different collective memories, up to the present day. It also discusses the function of the collective memories of Pauling's discovery for contemporary biomedical research. Copyright 2002 Wiley-Liss, Inc.

Are we hammering square pegs into round holes? An investigation of the meta-analyses of reading research with students who are d/Deaf or hard of hearing and students who are hearing.

PubMed

Wang, Ye; Williams, Cheri

2014-01-01

In a qualitative meta-analysis, the researchers systematically reviewed qualitative and quantitative meta-analyses on reading research with PK-12 students published after the 2000 National Reading Panel (NRP) report. Eleven qualitative and 39 quantitative meta-analyses were reviewed examining reading research with typically developing hearing students, special education hearing students (including English Language Learners), and d/Deaf or hard of hearing (d/Dhh) students. Generally, the meta-analysis yielded findings similar to and corroborative of the NRP's. Contradictory results (e.g., regarding the role of rhyme awareness in reading outcomes) most often resulted from differing definitions of interventions and their measurements. The analysis provided evidence of several instructional approaches that support reading development. On the basis of the qualitative similarity hypothesis (Paul, 2010, 2012; Paul & Lee, 2010; Paul & Wang, 2012; Paul, Wang, & Williams, 2013), the researchers argue that these instructional strategies also should effectively support d/Dhh children's reading development.

Visualizing polarization singularities in Bessel-Poincaré beams.

PubMed

Shvedov, V; Karpinski, P; Sheng, Y; Chen, X; Zhu, W; Krolikowski, W; Hnatovsky, C

2015-05-04

We demonstrate that an annulus of light whose polarization is linear at each point, but the plane of polarization gradually rotates by π radians can be used to generate Bessel-Poincaré beams. In any transverse plane this beam exhibits concentric rings of polarization singularities in the form of L-lines, where the polarization is purely linear. Although the L-lines are invisible in terms of light intensity variations, we present a simple way to visualize them as dark rings around a sharp peak of intensity in the beam center. To do this we use a segmented polarizer whose transmission axes are oriented differently in each segment. The radius of the first L-line is always smaller than the radius of the central disk of the zero-order Bessel beam that would be produced if the annulus were homogeneously polarized and had no phase circulation along it.

Linear segmentation algorithm for detecting layer boundary with lidar.

PubMed

Mao, Feiyue; Gong, Wei; Logan, Timothy

2013-11-04

The automatic detection of aerosol- and cloud-layer boundary (base and top) is important in atmospheric lidar data processing, because the boundary information is not only useful for environment and climate studies, but can also be used as input for further data processing. Previous methods have demonstrated limitations in defining the base and top, window-size setting, and have neglected the in-layer attenuation. To overcome these limitations, we present a new layer detection scheme for up-looking lidars based on linear segmentation with a reasonable threshold setting, boundary selecting, and false positive removing strategies. Preliminary results from both real and simulated data show that this algorithm cannot only detect the layer-base as accurate as the simple multi-scale method, but can also detect the layer-top more accurately than that of the simple multi-scale method. Our algorithm can be directly applied to uncalibrated data without requiring any additional measurements or window size selections.

All-fiber passively Q-switched thulium-doped fiber laser by using a holmium-doped fiber as saturable absorber

NASA Astrophysics Data System (ADS)

Durán Sánchez, M.; Álvarez-Tamayo, R. I.; Posada-Ramírez, B.; Alaniz-Baylón, J.; Bravo-Huerta, E.; Santiago-Hernández, H.; Hernández-Arriaga, M. V.; Bello-Jiménez, Miguel; Ibarra-Escamilla, B.; Kuzin, E. A.

2018-02-01

We report a linear cavity all-fiber passive Q-switched thulium-doped fiber laser operating at the 2 μm wavelength range. The laser configuration is based on a thulium-doped fiber used as a gain medium and an unpumped segment of holmium-doped fiber which acts as a fiber saturable absorber. The cavity is formed by a fiber optical loop mirror and the flat end facet of the holmium-doped fiber. The fiber segments as saturable absorber is a 1-m long single mode doubleclad holmium-doped fiber. Q-switched pulses are obtained at the wavelength of 2024.5 nm with a pulse width of 1.1 μs. The pulse repetition rate increases as a linear function of the applied pump power. The maximum pulse repetition rate of 100 kHz was obtained with a pump power of 2.4 W.

Polar versus Cartesian velocity models for maneuvering target tracking with IMM

NASA Astrophysics Data System (ADS)

Laneuville, Dann

This paper compares various model sets in different IMM filters for the maneuvering target tracking problem. The aim is to see whether we can improve the tracking performance of what is certainly the most widely used model set in the literature for the maneuvering target tracking problem: a Nearly Constant Velocity model and a Nearly Coordinated Turn model. Our new challenger set consists of a mixed Cartesian position and polar velocity state vector to describe the uniform motion segments and is augmented with the turn rate to obtain the second model for the maneuvering segments. This paper also gives a general procedure to discretize up to second order any non-linear continuous time model with linear diffusion. Comparative simulations on an air defence scenario with a 2D radar, show that this new approach improves significantly the tracking performance in this case.

Frequency-Domain Analysis of Diffusion-Cooled Hot-Electron Bolometer Mixers

NASA Technical Reports Server (NTRS)

Skalare, A.; McGrath, W. R.; Bumble, B.; LeDuc, H. G.

1998-01-01

A new theoretical model is introduced to describe heterodyne mixer conversion efficiency and noise (from thermal fluctuation effects) in diffusion-cooled superconducting hot-electron bolometers. The model takes into account the non-uniform internal electron temperature distribution generated by Wiedemann-Franz heat conduction, and accepts for input an arbitrary (analytical or experimental) superconducting resistance-versus- temperature curve. A non-linear large-signal solution is solved iteratively to calculate the temperature distribution, and a linear frequency-domain small-signal formulation is used to calculate conversion efficiency and noise. In the small-signal solution the device is discretized into segments, and matrix algebra is used to relate the heating modulation in the segments to temperature and resistance modulations. Matrix expressions are derived that allow single-sideband mixer conversion efficiency and coupled noise power to be directly calculated. The model accounts for self-heating and electrothermal feedback from the surrounding bias circuit.

Robust tissue-air volume segmentation of MR images based on the statistics of phase and magnitude: Its applications in the display of susceptibility-weighted imaging of the brain.

PubMed

Du, Yiping P; Jin, Zhaoyang

2009-10-01

To develop a robust algorithm for tissue-air segmentation in magnetic resonance imaging (MRI) using the statistics of phase and magnitude of the images. A multivariate measure based on the statistics of phase and magnitude was constructed for tissue-air volume segmentation. The standard deviation of first-order phase difference and the standard deviation of magnitude were calculated in a 3 x 3 x 3 kernel in the image domain. To improve differentiation accuracy, the uniformity of phase distribution in the kernel was also calculated and linear background phase introduced by field inhomogeneity was corrected. The effectiveness of the proposed volume segmentation technique was compared to a conventional approach that uses the magnitude data alone. The proposed algorithm was shown to be more effective and robust in volume segmentation in both synthetic phantom and susceptibility-weighted images of human brain. Using our proposed volume segmentation method, veins in the peripheral regions of the brain were well depicted in the minimum-intensity projection of the susceptibility-weighted images. Using the additional statistics of phase, tissue-air volume segmentation can be substantially improved compared to that using the statistics of magnitude data alone. (c) 2009 Wiley-Liss, Inc.

Tracking cells in Life Cell Imaging videos using topological alignments.

PubMed

Mosig, Axel; Jäger, Stefan; Wang, Chaofeng; Nath, Sumit; Ersoy, Ilker; Palaniappan, Kannap-pan; Chen, Su-Shing

2009-07-16

With the increasing availability of live cell imaging technology, tracking cells and other moving objects in live cell videos has become a major challenge for bioimage informatics. An inherent problem for most cell tracking algorithms is over- or under-segmentation of cells - many algorithms tend to recognize one cell as several cells or vice versa. We propose to approach this problem through so-called topological alignments, which we apply to address the problem of linking segmentations of two consecutive frames in the video sequence. Starting from the output of a conventional segmentation procedure, we align pairs of consecutive frames through assigning sets of segments in one frame to sets of segments in the next frame. We achieve this through finding maximum weighted solutions to a generalized "bipartite matching" between two hierarchies of segments, where we derive weights from relative overlap scores of convex hulls of sets of segments. For solving the matching task, we rely on an integer linear program. Practical experiments demonstrate that the matching task can be solved efficiently in practice, and that our method is both effective and useful for tracking cells in data sets derived from a so-called Large Scale Digital Cell Analysis System (LSDCAS). The source code of the implementation is available for download from http://www.picb.ac.cn/patterns/Software/topaln.

Smeared spectrum jamming suppression based on generalized S transform and threshold segmentation

NASA Astrophysics Data System (ADS)

Li, Xin; Wang, Chunyang; Tan, Ming; Fu, Xiaolong

2018-04-01

Smeared Spectrum (SMSP) jamming is an effective jamming in countering linear frequency modulation (LFM) radar. According to the time-frequency distribution difference between jamming and echo, a jamming suppression method based on Generalized S transform (GST) and threshold segmentation is proposed. The sub-pulse period is firstly estimated based on auto correlation function firstly. Secondly, the time-frequency image and the related gray scale image are achieved based on GST. Finally, the Tsallis cross entropy is utilized to compute the optimized segmentation threshold, and then the jamming suppression filter is constructed based on the threshold. The simulation results show that the proposed method is of good performance in the suppression of false targets produced by SMSP.

Evaluating and Improving the SAMA (Segmentation Analysis and Market Assessment) Recruiting Model

DTIC Science & Technology

2015-06-01

and rewarding me with your love every day. xx THIS PAGE INTENTIONALLY LEFT BLANK 1 I. INTRODUCTION A. THE UNITED STATES ARMY RECRUITING...the relationship between the calculated SAMA potential and the actual 2014 performance. The scatterplot in Figure 8 shows a strong linear... relationship between the SAMA calculated potential and the contracting achievement for 2014, with an R-squared value of 0.871. Simple Linear Regression of

The Relationship between the Shape of the Mental Number Line and Familiarity with Numbers in 5- to 9-Year Old Children: Evidence for a Segmented Linear Model

ERIC Educational Resources Information Center

Ebersbach, Mirjam; Luwel, Koen; Frick, Andrea; Onghena, Patrick; Verschaffel, Lieven

2008-01-01

This experiment aimed to expand previous findings on the development of mental number representation. We tested the hypothesis that children's familiarity with numbers is directly reflected by the shape of their mental number line. This mental number line was expected to be linear as long as numbers lay within the range of numbers children were…

Physics and our View of the World

NASA Astrophysics Data System (ADS)

Hilgevoord, Jan

1994-11-01

Foreword; 1. Introduction JAN HILGEVOORD; 2. Questioning the answers GERARD T. HOOFT; 3. Theories of everything JOHN BARROW; 4. The scientific view of the world DENNIS DIEKS; 5. Enlarging the world ERNAN McMULLIN; 6. The world of empiricism BAS VAN FRAASSEN; 7. Has the scientific view of the world a special status compared with other views? PAUL FEYERABEND; 8. Quantum theory and our view of the world PAUL FEYERABEND; 9. Interpretation of science - science as interpretation BAS VAN FRAASSEN; 10. Problems in debates about physics and religion WILLEM DREES; 11. The mind of God PAUL DAVIES; 12. The sources of models for God: metaphysics or metaphor? MARY HESSE; 13. Discussion.

Compact Dexterous Robotic Hand

NASA Technical Reports Server (NTRS)

Lovchik, Christopher Scott (Inventor); Diftler, Myron A. (Inventor)

2001-01-01

A compact robotic hand includes a palm housing, a wrist section, and a forearm section. The palm housing supports a plurality of fingers and one or more movable palm members that cooperate with the fingers to grasp and/or release an object. Each flexible finger comprises a plurality of hingedly connected segments, including a proximal segment pivotally connected to the palm housing. The proximal finger segment includes at least one groove defining first and second cam surfaces for engagement with a cable. A plurality of lead screw assemblies each carried by the palm housing are supplied with power from a flexible shaft rotated by an actuator and output linear motion to a cable move a finger. The cable is secured within a respective groove and enables each finger to move between an opened and closed position. A decoupling assembly pivotally connected to a proximal finger segment enables a cable connected thereto to control movement of an intermediate and distal finger segment independent of movement of the proximal finger segment. The dexterous robotic hand closely resembles the function of a human hand yet is light weight and capable of grasping both heavy and light objects with a high degree of precision.

Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir.

PubMed

Johnson, Todd J; Gupta, Kavita M; Fabian, Judit; Albright, Theodore H; Kiser, Patrick F

2010-02-19

Dual segment polyurethane intravaginal rings (IVRs) were fabricated to enable sustained release of antiretroviral agents dapivirine and tenofovir to prevent the male to female sexual transmission of the human immunodeficiency virus. Due to the contrasting hydrophilicity of the two drugs, dapivirine and tenofovir were separately formulated into polymers with matching hydrophilicity via solvent casting and hot melt extrusion. The resultant drug loaded rods were then joined together to form dual segment IVRs. Compression testing of the IVRs revealed that they are mechanically comparable to the widely accepted NuvaRing IVR. Physical characterization of the individual IVR segments using wide angle X-ray scattering and differential scanning calorimetry determined that dapivirine and tenofovir are amorphous and crystalline within their polymeric segments, respectively. In vitro release of tenofovir from the dual segment IVR was sustained over 30 days while dapivirine exhibited linear release over the time period. A 90 day accelerated stability study confirmed that dapivirine and tenofovir are stable in the IVR formulation. Altogether, these results suggest that multisegment polyurethane IVRs are an attractive formulation for the sustained vaginal delivery of drugs with contrasting hydrophilicity such as dapivirine and tenofovir. 2009 Elsevier B.V. All rights reserved.

49 CFR Appendix B to Part 604 - Reasons for Removal

Code of Federal Regulations, 2012 CFR

2012-10-01

... honest mistake. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn... performing it. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn., 1968... force. In addition, no other policy of insurance has taken its place. Black's Law Dictionary, Revised...

49 CFR Appendix B to Part 604 - Reasons for Removal

Code of Federal Regulations, 2013 CFR

2013-10-01

... honest mistake. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn... performing it. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn., 1968... force. In addition, no other policy of insurance has taken its place. Black's Law Dictionary, Revised...

49 CFR Appendix B to Part 604 - Reasons for Removal

Code of Federal Regulations, 2014 CFR

2014-10-01

... honest mistake. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn... performing it. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn., 1968... force. In addition, no other policy of insurance has taken its place. Black's Law Dictionary, Revised...

Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

PubMed

Black, Donald W

2018-02-01

One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

Classical Sax: Conversation with Paul Brodie.

ERIC Educational Resources Information Center

Row, David W.

1984-01-01

Paul Brodie, the most recorded concert saxophonist in the history of the instrument, talks about a number of topics, including his career, differences among saxophonists, mixing styles of playing, the effectiveness of music schools, and whether it is necessary to understand the structure of the piece being played. (RM)

The Carbon New Age

DTIC Science & Technology

2010-03-01

these allotropes show that they all have the same basic motif, namely, the benzene ring. Linus Pauling was one the first scientists to understand the...nature of these allotropes and in his 1950’s masterpiece “The Nature of the Chemical Bond”, Pauling describes graphite (the only allotrope that was

Deputy to the Commanding General

DTIC Science & Technology

2012-10-18

Kneller "The best way to have a good idea is to have a lot of ideas." — Dr. Linus Pauling "To raise new questions, new possibilities, to regard old...Development & Integration Directorate (CDID) Capability Portfolio Overview COL Courtney W. Paul 06 June 2012 MSCoE CDID Organization

Sixteen Textbook Authors Respond.

ERIC Educational Resources Information Center

Hewitt, John P.; And Others

1988-01-01

The articles on textbook publication written by Sheryl Fullerton and Franklin C. Graham were responded to by: John Hewitt, Henry Tischler, George Ritzer, Paul Baker, Erich Goode, D. Stanley Eitzen, Jon Shepard, Richard Schaefer, Caroline Persell, Beth Hess, Paul Zopf, Jr., Jeanne Ballantine, Duane Monette, Mary Ann Lamanna, John Macionis, and…

Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

DOT National Transportation Integrated Search

2013-05-01

The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

A Response to Paul Stapleton's "Critiquing Research Methodology"

ERIC Educational Resources Information Center

Ross, Steven J.

2006-01-01

Paul Stapleton's (2006) critique of quantitative research brings to the surface some common interpretive problems arising when experimental and quasi-experimental research designs are compared. While Stapleton may be correct in pointing out the superiority of experimental research designs because they best eliminate the influence of extraneous…

Abiotic Remediation of Nitro-Aromatic Groundwater Contaminants by Zero-Valent Iron

DTIC Science & Technology

1994-03-18

Paul G. Tratnyek 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Department of Environmental Science N/A...REMEDIATION OF NITRO-AROMATIC GROUNDWATER CONTAMINANTS BY ZERO-VALENT IRON Abinash Agrmwal and Paul G. Tratnyek Department of Environmental Science and

49 CFR Appendix B to Part 604 - Reasons for Removal

Code of Federal Regulations, 2010 CFR

2010-10-01

... honest mistake. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn... performing it. Black's Law Dictionary, Revised Fourth Edition, West Publishing Company, St. Paul, Minn., 1968... force. In addition, no other policy of insurance has taken its place. Black's Law Dictionary, Revised...

Paul Langerhans: a prilgrim "traveling" from functional histology to marine biology.

PubMed

Raica, Marius; Cimpean, Anca Maria

2017-06-01

The nineteenth century was the time of a real revolution in science and medicine. A lot of seminal discoveries in medicine and biology were done in this time, and many of them were coincident with the introduction of the compound microscope by Hermann van Deijl and the standard histological technique by Paul Ehrlich. The main tissue types and individual cells were characterized and originally classified more than hundred years ago, although less attention was paid to their basic functions. This was mainly due to the modality of tissue specimen processing that allowed particularly detailed descriptive studies. Even so, we can notice some attempts to correlate the structure with the function. The German scientist Paul Langerhans, well-known for the discovery of Langerhans islets of the pancreas and Langerhans cells from the epidermis, tried to change the conventional fate of morphological studies introducing in his works functional hypothesis based on traditional microscopic observations even from the beginning of his scientific career. Paul Langerhans was a complex personality of the second half of the nineteenth century, not only in medicine, but also in other fields of biology. In the present review, presented is the life and research activity of Paul Langerhans, not only because of the importance of his discoveries, but also for perspectives that were opened by these findings in unexpected fields of medicine and biology.

Robust Classification and Segmentation of Planar and Linear Features for Construction Site Progress Monitoring and Structural Dimension Compliance Control

NASA Astrophysics Data System (ADS)

Maalek, R.; Lichti, D. D.; Ruwanpura, J.

2015-08-01

The application of terrestrial laser scanners (TLSs) on construction sites for automating construction progress monitoring and controlling structural dimension compliance is growing markedly. However, current research in construction management relies on the planned building information model (BIM) to assign the accumulated point clouds to their corresponding structural elements, which may not be reliable in cases where the dimensions of the as-built structure differ from those of the planned model and/or the planned model is not available with sufficient detail. In addition outliers exist in construction site datasets due to data artefacts caused by moving objects, occlusions and dust. In order to overcome the aforementioned limitations, a novel method for robust classification and segmentation of planar and linear features is proposed to reduce the effects of outliers present in the LiDAR data collected from construction sites. First, coplanar and collinear points are classified through a robust principal components analysis procedure. The classified points are then grouped using a robust clustering method. A method is also proposed to robustly extract the points belonging to the flat-slab floors and/or ceilings without performing the aforementioned stages in order to preserve computational efficiency. The applicability of the proposed method is investigated in two scenarios, namely, a laboratory with 30 million points and an actual construction site with over 150 million points. The results obtained by the two experiments validate the suitability of the proposed method for robust segmentation of planar and linear features in contaminated datasets, such as those collected from construction sites.

Paul Vallas for Sale

ERIC Educational Resources Information Center

Dessoff, Alan

2012-01-01

Veteran Superintendent Paul Vallas, who has led turnaround efforts in major urban districts in Chicago, Philadelphia and New Orleans, has started a new venture that he expects will broaden his reach and extend the reform movement. The Vallas Group, headed by Vallas, now interim superintendent of the Bridgeport (Connecticut) Public Schools, is…

70. Photocopy of photograph (original print in the Minnesota Historical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

70. Photocopy of photograph (original print in the Minnesota Historical Society, St. Paul, Minnesota, 1904. #18613g. Photographer: Albert Munson) VIEW TO WEST, SHOWING FALSEWORK USED IN RECONTRUCTING THE HIGH BRIDGE, 1904. - Smith Avenue High Bridge, Smith Avenue between Cherokee Avenue & Cliff Street, Saint Paul, Ramsey County, MN

Paul Zindel: Flirting with the Bizarre.

ERIC Educational Resources Information Center

Winarski, Diana L.

1994-01-01

Profiles Paul Zindel, the best-selling author of childrens' and adolescents' novels who combines hyperbole and pathos in such works as "The Pigman;""My Darling, My Hamburger;" and "The Pigman and Me." Zindel is also the author of the play "The Effect of Gamma Rays on Man-in-the-Moon Marigolds." (MDM)

Nature, Human Nature, and Solutions to Problems.

ERIC Educational Resources Information Center

Pedrini, D. T.; Pedrini, B. C.

This paper promotes an undergraduate course that would discuss the great ideas of Plato, St. Paul, Karl Marx, Sigmund Freud, Jean Paul Sartre, B. F. Skinner, and Konrad Lorenz. This course would help students understand human values and behaviors while focusing on historical, world, and national problems. Tentative solutions would then be…

A Report on Administrative Compensation Planning for St. Paul Public School Personnel.

ERIC Educational Resources Information Center

Hooker, Clifford P.; Mueller, Van D.

This report describes and analyzes various devices and techniques that may be utilized in planning local school administrative compensation. The document outlines broad overall goals for compensation planning, describes and evaluates the application of a compensation plan in the St. Paul schools, and proposes alternative strategies for…

Speaking Personally--With Paul Avon

ERIC Educational Resources Information Center

Martin, D'Arcy

2012-01-01

This article presents an interview with Paul Avon, the former executive director of the Canadian Virtual College Consortium. Avon has spent over fifteen years in the distance learning (DL) field managing the production and delivery of online learning at TVOntario, Humber College, the Sri Lankan National Online Distance Education Service, and the…

Guidelines for Software Engineering Education Version 1.0

DTIC Science & Technology

1999-11-01

Turbo Pascal and Software Design. Sudbury, Massachusetts: Jones and Bartlett, 1997. " Deitel, Harvey M. & Deitel, Paul J. C++: How to Program . Upper...Saddle River, New Jersey: Prentice-Hall, 1997. " Deitel, Harvey M. & Deitel, Paul J. Java: How to Program . Upper Saddle River, New Jersey: Prentice-Hall

Molecular Orbital (Hückel) Theory and Linus Pauling: A Historical Perspective

NASA Astrophysics Data System (ADS)

Sharma, Brahama D.

1996-08-01

This short article offers evidence contrary to the belief that Linus Pauling was somehow opposed to Hückel-type calculations and that he therefore provided little or no support to the school of scientists in the '60s who were engaged in these semiempirical calculations.

Linus Pauling Memorial Lectures

Science.gov Websites

Institute for Science, Engineering and Public Policy Home About The Institute Format/Policy Pauling Memorial Lectures Science, Engineering and Public Policy 2017-2018 Sabbatical Year Taking a Year Physics to the New Philosophy Terry Bristol Institute for Science, Engineering and Public Policy 7:00pm

Improving Success in Developmental Mathematics: An Interview with Paul Nolting

ERIC Educational Resources Information Center

Boylan, Hunter R.

2011-01-01

This article presents an interview with Dr. Paul Nolting, a national expert in assessing individual math learning problems, developing effective student learning strategies, and assessing institutional variables that affect math success. Since his dissertation in 1986 on improving math success with study skills Dr. Nolting has consulted with over…

13. Photocopy of 1875 stereograph. Original in Paul A. Kohl's ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopy of 1875 stereograph. Original in Paul A. Kohl's office, Tower Grove, Missouri Botanical Garden. HENRY SHAW AND TWO GUESTS IN HIS LANDAU DRAWN BY A MATCHED PAIR IN FRONT OF THE EAST GATE - Tower Grove Park, East Gate Entrance, 4255 Arsenal Street, Saint Louis, Independent City, MO

SeaBASS 2012: A Marine BioAcoustics Summer School

DTIC Science & Technology

2012-09-30

accepted from six different countries (USA & Puerto Rico, Italy, United Kingdom, Greece, Canada, and Austria). Advertising for SeaBASS was published...there was so much good and varied information in all the lectures, I would have to give it to Paul for his storytelling . • Paul Nachtigall’s lecture

Paul Ricoeur, Memory, and the Historical Gaze: Implications for Education Histories

ERIC Educational Resources Information Center

Colby, Sherri Rae

2012-01-01

In this article, the author shares the potential applications of Paul Ricoeur's philosophies of history, memory, and narrative to the interpretation of educational histories, and those histories' life spans: moving cyclically from early conception, to evidentiary construction, to published dissemination; and ultimately to death or immortality. Her…

76 FR 38621 - New England Fishery Management Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

... Street, Mill 2, Newburyport, MA 01950. FOR FURTHER INFORMATION CONTACT: Paul J. Howard, Executive... Monkfish Advisory Panel (AP) will meet to develop a detailed problem statement based on the list of issues... other auxiliary aids should be directed to Paul J. Howard, Executive Director, at (978) 465- 0492, at...

77 FR 28421 - Supplemental Draft Environmental Impact Statement for the Central Corridor Light Rail Transit...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Supplemental Draft Environmental Impact Statement for the Central Corridor Light Rail Transit Project, Minneapolis and Saint Paul, MN... Minneapolis and Saint Paul downtown areas as well as the University of Minnesota and the State Capitol complex...

78 FR 21141 - Changes in Flood Hazard Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... Center at www.msc.fema.gov . FOR FURTHER INFORMATION CONTACT: Luis Rodriguez, Chief, Engineering...). County Judge, Paul North Pecos- La Elizondo Tower, 101 Trinidad Street, West Nueva Street, Suite 420, San..., Bexar Works Department, 233 06-2935P). County Judge, Paul North Pecos- La Elizondo Tower, 101 Trinidad...