Differential mobility spectroscopy for chemical agent detection

NASA Astrophysics Data System (ADS)

Griffin, M. Todd

2006-05-01

General Dynamics ATP (GDATP) and Sionex Corporation (Sionex) are carrying out a cooperative development for a handheld chemical agent detector, being called JUNO TM, which will have lower false positives, higher sensitivity, and improved interference rejection compared with presently available detectors. This enhanced performance is made possible by the use of a new principle of ion separation called Differential Mobility Spectrometry (DMS). The enhanced selectivity is provided by the field tunable nature of the Sionex differential mobility technology (microDMxTM) which forms the analytical heart of the JUNO system and enables fingerprinting of molecules by characterization of the ionized molecular behavior under multiple electric field conditions. This enhanced selectivity is valuable in addressing not only the traditional list of chemical warfare agents (CWA) but also the substantial list of Toxic Industrial Compounds (TICs) and Toxic Industrial Materials (TIMs) which may be released in warfare or terrorist situations. Experimental results showing the ability of the microDMx to reject interferences, detect and resolve live agents are presented. An additional breakthrough in the technology was realized by operating the device at a reduced pressure of around 0.5 atmospheres. This reduced pressure operation resulted in roughly doubling the spectrometers resolution over what has previously been reported [1]. Advances have also been made in power consumption and packaging leading to a device suitable for portable, handheld, applications. Experimental results illustrating the performance of the microDMx technology employed in JUNO are highlighted.

Survey of how different groups of veterinarians manage the use of neuromuscular blocking agents in anesthetized dogs.

PubMed

Martin-Flores, Manuel; Sakai, Daniel M; Campoy, Luis; Gleed, Robin D

2018-03-23

To analyze practice habits associated with the use, reversal and monitoring of nondepolarizing neuromuscular blocking agents (NMBAs) in dogs by different groups of veterinarians. Online anonymous survey to veterinarians. Data from 390 answered surveys. A questionnaire was sent to e-mail list servers of the American College of Veterinary Anesthesia and Analgesia (ACVAA-list), Sociedad Española de Anestesia y Analgesia Veterinaria (SEEAV-list), Colégio Brasileiro de Anestesiologia Veterinária (Brazilian College of Veterinary Anesthesiology; CBAV-list) and American College of Veterinary Ophthalmologists (ACVO-list) to elicit information regarding use of NMBAs and reversal agents, monitoring techniques, criteria for redosing, reversing and assessing adequacy of recovery of neuromuscular function. Binomial logistic regression was used to test for association between responses and group of veterinarians in selected questions. Veterinarians of the ACVO-list use NMBAs on a higher fraction of their caseload than other groups (all p < 0.0001). Subjective assessment (observation) of spontaneous movement, including spontaneous breathing, is the most common method for assessing neuromuscular function (43% of pooled responses); 18% of participants always reverse NMBAs, whereas 16% never reverse them. Restoration of neuromuscular function is assessed subjectively by 35% of respondents. Residual neuromuscular block is the most common concern regarding the use of NMBAs for all groups of veterinarians. Side effects of reversal agents (anticholinesterases) were of least concern for all groups. While most veterinarians are concerned about residual neuromuscular block, relatively few steps are implemented to reduce the risks of this complication, such as routine use of quantitative neuromuscular monitoring or routine reversal of NMBAs. These results suggest a limitation in transferring information among groups of veterinarians, or in implementing techniques suggested by scientific research. Copyright © 2018 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

Inactivation of avirulent Yersinia pestis in beef bologna by gamma irradiation

USDA-ARS?s Scientific Manuscript database

Yersinia pestis, a psychrotrophic pathogen capable of growth at refrigeration temperatures, can cause pharyngeal and gastrointestinal plague in humans as a result of eating contaminated foods. Because Y. pestis is listed as a select agent for food safety and defense, evaluation of food safety interv...

Literacy Agents Online: E-Discussion Forums for Advancing Adults' Literacy Practices

ERIC Educational Resources Information Center

Guzzetti, Barbara J.; Foley, Leslie M.

2014-01-01

This study explored how adults used a self-selected online forum to advance their own and others' literacy practices. The study was a discourse-centered online ethnography using triangulated methods, including analysis of list archives, semi-structured and informal interviews, and document collection. These data were analyzed by discourse…

EXPOSURE DOSE REPONSE MODELING FOR THE EFFECTS OF HAZARDOUS AIR POLLUTANTS ON HEALTH: TRICHLOROETHYLENE

EPA Science Inventory

Trichloroethylene (TCE) is a neurotoxic volatile organic compound (VOC) that is produced in large quantities as a degreasing agent and general solvent, and it appears on the list of 188 HAPs specified by the Clean Air Act Amendments of 1990. TCE was selected as a model VOC for de...

Potential Effects of Rift Valley Fever in the United States

USDA-ARS?s Scientific Manuscript database

Rift Valley fever virus (RVFV) has been the cause of disease outbreaks throughout Africa and the Arabian Peninsula, and the infection often results in heavy economic costs through loss of livestock. If RVFV, which is common to select agent lists of the US Department of Health and Human Services and ...

Web based listing of agents associated with new onset work-related asthma.

PubMed

Rosenman, K D; Beckett, W S

2015-05-01

Work-related asthma is common and yet remains a challenge to diagnose. Access to a listing of agents associated with work-related asthma has been suggested as useful in assisting in the diagnosis. The Association of Occupational and Environmental Clinics (AOEC) developed criteria that were used to review the peer-reviewed medical literature published in English. Based on this review, substances were designated either as a sensitizing agent or an irritant. The reviews were conducted by a board certified internist/pulmonologist/occupational medicine specialist from 2002 to 2007 and a board certified internist/occupational medicine physician from 2008- date. All reviews were then reviewed by the nine member AOEC board of directors. The original list of agents associated with new onset work-related asthma was derived from the tables of a text book on work-related asthma. After 13 years of review, there are 327 substances designated as asthma agents on the AOEC list; 173 (52.9%) coded as sensitizers, 35 (10.7%) as generally recognized as an asthma causing agent, four (1.2%) as irritants, two (0.6%) as both a sensitizer and an irritant and 113(34.6%) agents that still need to be reviewed. The AOEC has developed a readily available web based listing of agents associated with new onset work-related asthma in adults. The listing is based on peer-reviewed criteria. The listing is updated twice a year. Regular review of the peer-reviewed medical literature is conducted to determine whether new substances should be added to the list. Clinicians should find the list useful when considering the diagnosis of work-related asthma. Copyright © 2015 Elsevier Ltd. All rights reserved.

Whole genome sequence of two Rathayibacter toxicus strains reveals a tunicamycin biosynthetic cluster similar to Streptomyces chartreusis

USDA-ARS?s Scientific Manuscript database

Rathayibacter toxicus is a forage grass associated Gram-positive bacterium of major concern to food safety and agriculture. The species is listed by USDA-APHIS as a plant pathogen select agent due to the fact that it produces a tunicamycin-like toxin that is lethal to livestock. The complete genomes...

42 CFR 73.4 - Overlap select agents and toxins.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the Federal Register and will be listed on the CDC Web site at http://www.cdc.gov/. (2) If an excluded... CDC or APHIS. (i) The seizure of Bacillus anthracis, Brucella melitensis, Hendra virus, Nipah virus... telephone, facsimile, or e-mail. This report must be followed by submission of APHIS/CDC Form 4 within seven...

Implementation of a new technology for point detection

NASA Astrophysics Data System (ADS)

Petinarides, John; Griffin, M. Todd; Miller, Ranaan A.; Nazarov, Erkinjon G.; Bashall, Anthony D.

2005-05-01

General Dynamics ATP (GDATP) and Sionex Corporation (Sionex) are carrying out a cooperative development for a handheld chemical agent detector, being called JUNO, which will have lower false positives, higher sensitivity, and improved interference rejection compared with presently available detectors. This enhanced performance is made possible by the use of a new principle of ion separation called Differential Mobility Spectrometry (DMS). The enhanced selectivity is provided by the field tunable nature of the Sionex differential mobility technology (microDMxTM) which forms the analytical heart of the JUNO system and enables fingerprinting of molecules by characterization of the ionized molecular behavior under multiple electric field conditions. This enhanced selectivity is valuable in addressing not only the traditional list of chemical warfare agents (CWA) but also the substantial list of Toxic Industrial Compounds (TICs) and Toxic Industrial Materials (TIMs) which may be released in warfare or terrorist situations. Experimental results showing the ability of the microDMx to reject interferences, detect and resolve live agents are presented. An additional breakthrough in the technology was realized by operating the device at a reduced pressure of around 0.5 atmospheres. This reduced pressure operation resulted in roughly doubling the spectrometers resolution over what has previously been reported [1]. Advances have also been made in power consumption and packaging leading to a device suitable for portable, handheld, applications. Experimental results illustrating the performance of the microDMx technology employed in JUNO are highlighted.

Changing perspectives of stress gastritis prophylaxis.

PubMed

Smythe, M A; Zarowitz, B J

1994-09-01

To present recent advances in stress gastritis prophylaxis in the critically ill and review considerations in selection of a prophylactic agent. Information was obtained from MEDLINE search, reference lists from articles identified in search, and from review articles. Emphasis was placed on controlled trials conducted within the last 5 years. All literature was assessed for methodology, results, and conclusions. Results of prospective, randomized trials, and meta-analyses are summarized. Histamine2-receptor antagonists, antacids, and sucralfate appear equally effective in preventing stress gastritis in the critically ill. A definitive cause-effect relationship between histamine2-receptor antagonists and increased incidence of nosocomial pneumonia has not yet been established. The indications for using a prophylactic agent and consideration in selecting an agent should include an evaluation of the following: risk factors for gastritis including the type of intensive care patient, comparative efficacy, adverse effects, drug interactions, cost, and ease of administration. The least expensive, safest agent requiring minimal monitoring is sucralfate. Prevention of stress gastritis has never been shown to reduce morbidity or mortality significantly. Controversies still exist regarding the need to provide prophylaxis, the choice of an agent, and the relative importance of previously identified risk factors. Further well-designed studies are needed before consensus can be reached.

Rathayibacter toxicus: how a bacterium hitches a ride on a nematode to invade grass seeds and produce a toxin harmful to livestock

USDA-ARS?s Scientific Manuscript database

Rathayibacter toxicus is a forage grass associated Gram-positive bacterium of major concern to food safety and agriculture. This species is listed by USDA-APHIS as a plant pathogen select agent because it produces a tunicamycin-like toxin that is lethal to livestock and may be vectored by nematode s...

Development and comparison of TaqMan-based real-time PCR assays for detection and differentiation of Ralstonia solanacearum strains

USDA-ARS?s Scientific Manuscript database

Bacterial wilt caused by Ralstonia solanacearum is destructive to many plant species worldwide. The race 3 biovar 2 (r3b2) strains of R. solanacearum infect potatoes in temperature climates and are listed as select agents by the U.S. government. TaqMan-based real-time quantitative PCR (qPCR) is comm...

High temperature lubricants. (Latest citations from the US Patent bibliographic file with exemplary claims). Published Search

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-01-01

The bibliography contains citations of selected patents concerning high temperature synthetic and natural lubricating compositions. Thickening agents, thermal stabilizers, polymeric additives, antioxidants, and preservatives are included relative to such lubricants as greases, oils, and soaps. Manufacturing methods and various applications are included. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

78 FR 33692 - Implementation of the Understandings Reached at the 2012 Australia Group (AG) Plenary Meeting and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... Australia Group (AG) ``List of Biological Agents for Export Control,'' as follows: b.1. Reconstructed.... Bacteria identified on the Australia Group (AG) ``List of Biological Agents for Export Control,'' as... Group (AG) ``List of Plant Pathogens for Export Control'']. b. Fungi, as follows: b.1. Colletotrichum...

Time-and Concentration-Dependent Cytotoxicity of Ricin in Human Lung Epithelial Cells

DTIC Science & Technology

2007-07-01

lectin, ricin communis agglutinin, which is not directly cytotoxic but does have an affinity for red blood cells and can lead to agglutination and...Time- and Concentration-Dependent Cytotoxicity of Ricin in Human Lung Epithelial Cells Sharmaine Ramasamy and David Proll Human...Disease Control (CDC) Select Agent List. Using human small airway epithelial cells , this is the first study to investigate the time- and dose-dependent

Anti-EGFR Agents: Current Status, Forecasts and Future Directions.

PubMed

Kwapiszewski, Radoslaw; Pawlak, Sebastian D; Adamkiewicz, Karolina

2016-12-01

The epidermal growth factor receptor (EGFR) is one of the most important and attractive targets for specific anticancer therapies. It is a robust regulator of pathways involved in cancer pathogenesis and progression. Thus far, clinical trials have demonstrated the benefits of monoclonal antibodies and synthetic tyrosine kinase inhibitors in targeting this receptor; however, novel strategies are still being developed. This article reviews the current state of efforts in targeting the EGFR in cancer therapy. Following a brief characterization of EGFR, we will present a complete list of anti-EGFR agents that are already approved, and available in clinical practice. Aside from the indications, we will present the sales forecasts and expiry dates of product patents for the selected agents. Finally, we discuss the novel anti-EGFR strategies that are currently in preclinical development.

Subtle Nonlinearity in Popular Album Charts

NASA Astrophysics Data System (ADS)

Bentley, R. Alexander; Maschner, Herbert D. G.

Large-scale patterns of culture change may be explained by models of self organized criticality, or alternatively, by multiplicative processes. We speculate that popular album activity may be similar to critical models of extinction in that interconnected agents compete to survive within a limited space. Here we investigate whether popular music albums as listed on popular album charts display evidence of self-organized criticality, including a self-affine time series of activity and power-law distributions of lifetimes and exit activity in the chart. We find it difficult to distinguish between multiplicative growth and critical model hypotheses for these data. However, aspects of criticality may be masked by the selective sampling that a "Top 200" listing necessarily implies.

9 CFR 205.208 - Distribution of portions of master list-registration-information to non-registrants on request.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., and selling agents,” “regular” distribution of “portions” of the master list, furnishing of “oral... receive portions of the master list only for oranges, and thus take cattle free and clear of security... buyers, commission merchants, and selling agents are not intended to be liable for errors or other...

An application of a proposed framework for formulary listing in low-income countries: the case of Côte d'Ivoire.

PubMed

Diaby, Vakaramoko; Lachaine, Jean

2011-11-01

The General Mutual Benefit Fund for Civil Servants and State Employees of Côte d'Ivoire (MUGEFCI; Mutuelle Générale des Fonctionnaires et Agents de l'État de Côte d'Ivoire) is a health mutual fund providing coverage (medical consultations, laboratory tests and treatment) for its enrolees (government officials and agents). This organization aims to improve its current drug reimbursement process because of budgetary constraints. One method of achieving this is to implement a formulary-listing framework specifically developed for low-income countries. The aim of this study was to evaluate the feasibility of developing a new formulary for the MUGEFCI in Côte d'Ivoire, by implementing a formulary-listing framework specifically designed for under-researched settings. The application of this formulary-listing framework (based on multi-criteria decision analysis [MCDA]) consisted of four steps. First, relevant formulary-listing criteria and their levels of variation were identified and weighted according to their importance in the decision making around drug reimbursement. Second, a set of priority treatments to be assessed was determined. Once the treatments eligible for reimbursement were determined, scores were assigned to these treatments according to their performance on the formulary-listing criteria levels. Finally, a composite league table (weighted matrix) was constructed to rank the set of treatments by priority order of reimbursement. A budget-impact analysis (BIA) was also conducted to appraise the economic implications of the new composite drugs league table. The extent to which the new priority list of reimbursable drugs was affordable for the MUGEFCI was then measured. Policy makers in Côte d'Ivoire considered severity of disease and cost effectiveness of treatment to be the most significant criteria for priority reimbursement of drugs. This translated into a general preference for antimalarials, treatments for asthma and antibacterials for urinary tract infection. Moreover, the results of the BIA suggest that the new priority list of reimbursable drugs would be affordable if the real economic impact of drugs per member is less than $US66. Over this threshold, the MUGEFCI would have to select reimbursable drugs according to their rank in the priority list and their respective budget impact per patient (cost per patient). This selection would start from the first treatment, going down the list until the $US66 per patient is exhausted. It was possible to use MCDA to simultaneously consider different decision criteria for drug reimbursement in Côte d'Ivoire; therefore, it is feasible to use MCDA to establish a formulary for low-income countries. The application of this method is a step towards transparency in policy making.

MORE Resiliency in the Rehabilitation of Active Duty Service Members

DTIC Science & Technology

2017-10-01

Nothing to Report Significant changes in use or care of vertebrate animals. Not Applicable Significant changes in use of biohazards and/or select agents...Not Applicable 6. PRODUCTS: List any products resulting from the project during the reporting period. If there is nothing to report under a particular...Website(s) or other Internet site(s) Nothing to report 7 • Technologies or techniques Nothing to report • Inventions, patent applications , and/or licenses

Development of a matrix to evaluate the threat of biological agents used for bioterrorism.

PubMed

Tegnell, A; Van Loock, F; Baka, A; Wallyn, S; Hendriks, J; Werner, A; Gouvras, G

2006-10-01

Adequate public health preparedness for bioterrorism includes the elaboration of an agreed list of biological and chemical agents that might be used in an attack or as threats of deliberate release. In the absence of counterterrorism intelligence information, public health authorities can also base their preparedness on the agents for which the national health structures would be most vulnerable. This article aims to describe a logical method and the characteristics of the variables to be brought in a weighing process to reach a priority list for preparedness. The European Union, in the aftermath of the anthrax events of October 2001 in the United States, set up a task force of experts from multiple member states to elaborate and implement a health security programme. One of the first tasks of this task force was to come up with a list of priority threats. The model, presented here, allows Web-based updates for newly identified agents and for the changes occurring in preventive measures for agents already listed. The same model also allows the identification of priority protection action areas.

40 CFR 300.910 - Authorization of use.

Code of Federal Regulations, 2012 CFR

2012-07-01

... dispersants, surface washing agents, surface collecting agents, bioremediation agents, or miscellaneous oil... agents, surface collecting agents, bioremediation agents, or miscellaneous oil spill control agents on..., bioremediation agent, or miscellaneous oil spill control agent, including products not listed on the NCP Product...

40 CFR 300.910 - Authorization of use.

Code of Federal Regulations, 2013 CFR

2013-07-01

... dispersants, surface washing agents, surface collecting agents, bioremediation agents, or miscellaneous oil... agents, surface collecting agents, bioremediation agents, or miscellaneous oil spill control agents on..., bioremediation agent, or miscellaneous oil spill control agent, including products not listed on the NCP Product...

40 CFR 300.910 - Authorization of use.

Code of Federal Regulations, 2014 CFR

2014-07-01

... dispersants, surface washing agents, surface collecting agents, bioremediation agents, or miscellaneous oil... agents, surface collecting agents, bioremediation agents, or miscellaneous oil spill control agents on..., bioremediation agent, or miscellaneous oil spill control agent, including products not listed on the NCP Product...

40 CFR 300.910 - Authorization of use.

Code of Federal Regulations, 2010 CFR

2010-07-01

... dispersants, surface washing agents, surface collecting agents, bioremediation agents, or miscellaneous oil... agents, surface collecting agents, bioremediation agents, or miscellaneous oil spill control agents on..., bioremediation agent, or miscellaneous oil spill control agent, including products not listed on the NCP Product...

Chemical peeling in ethnic/dark skin.

PubMed

Roberts, Wendy E

2004-01-01

Chemical peeling for skin of color arose in ancient Egypt, Mesopotamia, and other ancient cultures in and around Africa. Our current fund of medical knowledge regarding chemical peeling is a result of centuries of experience and research. The list of agents for chemical peeling is extensive. In ethnic skin, our efforts are focused on superficial and medium-depth peeling agents and techniques. Indications for chemical peeling in darker skin include acne vulgaris, postinflammatory hyperpigmentation, melasma, scarring, photodamage, and pseudofolliculitis barbae. Careful selection of patients for chemical peeling should involve not only identification of Fitzpatrick skin type, but also determining ethnicity. Different ethnicities may respond unpredictably to chemical peeling regardless of skin phenotype. Familiarity with the properties each peeling agent used is critical. New techniques discussed for chemical peeling include spot peeling for postinflammatory hyperpigmentation and combination peels for acne and photodamage. Single- or combination-agent chemical peels are shown to be efficacious and safe. In conclusion, chemical peeling is a treatment of choice for numerous pigmentary and scarring disorders arising in dark skin tones. Familiarity with new peeling agents and techniques will lead to successful outcomes.

Characterization of Clinically Attenuated Burkholderia mallei by Whole-Genome Sequencing: Candidate Strain for Exclusion from Select Agent Lists

DTIC Science & Technology

2008-04-01

symptoms may have been related to endotoxin . Clinical signs in the ponies and the mule were either minimal (fever) or nonexistent. All 6 equids produced ...ponies, 1 mule, 1 donkey), natural hosts, for purposes of producing antibodies. Multiple high inocula were used in some cases. Unexpectedly SAVP1 appeared...that was experimentally infected in 6 equids (4 ponies, 1 mule, 1 donkey), natural hosts, for purposes of producing antibodies. Multiple high inocula

Multi-Agent Information Classification Using Dynamic Acquaintance Lists.

ERIC Educational Resources Information Center

Mukhopadhyay, Snehasis; Peng, Shengquan; Raje, Rajeev; Palakal, Mathew; Mostafa, Javed

2003-01-01

Discussion of automated information services focuses on information classification and collaborative agents, i.e. intelligent computer programs. Highlights include multi-agent systems; distributed artificial intelligence; thesauri; document representation and classification; agent modeling; acquaintances, or remote agents discovered through…

31 CFR 597.301 - Agent.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[FTO].” The SDN List is....gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter...

31 CFR 597.301 - Agent.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[FTO].” The SDN List is....gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter...

Bid purchasing of radiopharmaceuticals and radiopaque contrast media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swanson, D.P.; Jakubowski, D.L.; Shoup, L.K.

Use of product standardization and competitive-bid purchasing for radiopharmaceuticals and radiopaque contrast media in a 1000-bed teaching hospital is described. The hospital's use of radiopharmaceuticals was reviewed, and all agents were listed with their product specifications and order quantity or frequency. Manufacturers and wholesalers were asked to submit unit prices for each of their products. Similar procedures were followed for radiopaque contrast media; wholesalers and manufacturers were asked to submit unit prices that would be guaranteed for a 12-month contract period. A nuclear pharmacist and radiologists reviewed the submitted bids and awarded contracts, basing their decisions primarily on product acceptabilitymore » and selection criteria and then on relative costs of the agents. Annual costs were reduced 16% ($16,500) for radiopharmaceuticals and 21.3% ($66,500) for radiopaque contrast media. The program also resulted in decreased inventory of radiopaque contrast media and in faster and less expensive acquisition of emergency orders. Working with the radiology department to compile a standard list of radiopharmaceuticals and radiopaque contrast media and soliciting competitive bids by vendors of these products resulted in annual savings of more than $83,000.« less

21 CFR 1300.02 - Definitions relating to listed chemicals.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Definitions relating to listed chemicals. 1300.02....02 Definitions relating to listed chemicals. (a) Any term not defined in this part shall have the... international transaction in a listed chemical by— (i) Negotiating contracts; (ii) Serving as an agent or...

Design and Solution-Phase Synthesis of Membrane-Targeting Lipopeptides with Selective Antibacterial Activity.

PubMed

Konai, Mohini M; Adhikary, Utsarga; Haldar, Jayanta

2017-09-18

Designing selective antibacterial molecules remains an unmet goal in the field of membrane-targeting agents. Herein, we report the rational design and synthesis of a new class of lipopeptides, which possess highly selective bacterial killing over mammalian cells. The selective interaction with bacterial over mammalian membranes was established through various spectroscopic, as well as microscopic experiments, including biophysical studies with the model membranes. A detailed antibacterial structure-activity relationship was delineated after preparing a series of molecules consisting of the peptide moieties with varied sequence of amino acids, such as d-phenylalanine, d-leucine, and d-lysine. Antibacterial activity was found to vary with the nature and positioning of hydrophobicity in the molecules, as well as number of positive charges. Optimized lipopeptide 9 did not show any hemolytic activity even at 1000 μg mL -1 and displayed >200-fold and >100-fold selectivity towards S. aureus and E. coli, respectively. More importantly, compound 9 was found to display good antibacterial activity (MIC 6.3-12.5 μg mL -1 ) against the five top most critical bacteria according to World Health Organization (WHO) priority pathogens list. Therefore, the results suggested that this new class of lipopeptides bear real promises for the development as future antibacterial agents. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Pharmacology of stimulants prohibited by the World Anti-Doping Agency (WADA)

PubMed Central

Docherty, J R

2008-01-01

This review examines the pharmacology of stimulants prohibited by the World Anti-Doping Agency (WADA). Stimulants that increase alertness/reduce fatigue or activate the cardiovascular system can include drugs like ephedrine available in many over-the-counter medicines. Others such as amphetamines, cocaine and hallucinogenic drugs, available on prescription or illegally, can modify mood. A total of 62 stimulants (61 chemical entities) are listed in the WADA List, prohibited in competition. Athletes may have stimulants in their body for one of three main reasons: inadvertent consumption in a propriety medicine; deliberate consumption for misuse as a recreational drug and deliberate consumption to enhance performance. The majority of stimulants on the list act on the monoaminergic systems: adrenergic (sympathetic, transmitter noradrenaline), dopaminergic (transmitter dopamine) and serotonergic (transmitter serotonin, 5-HT). Sympathomimetic describes agents, which mimic sympathetic responses, and dopaminomimetic and serotoninomimetic can be used to describe actions on the dopamine and serotonin systems. However, many agents act to mimic more than one of these monoamines, so that a collective term of monoaminomimetic may be useful. Monoaminomimietic actions of stimulants can include blockade of re-uptake of neurotransmitter, indirect release of neurotransmitter, direct activation of monoaminergic receptors. Many of the stimulants are amphetamines or amphetamine derivatives, including agents with abuse potential as recreational drugs. A number of agents are metabolized to amphetamine or metamphetamine. In addition to the monoaminomimetic agents, a small number of agents with different modes of action are on the list. A number of commonly used stimulants are not considered as Prohibited Substances. PMID:18500382

A retrospective study of non-suppurative encephalitis in beef cattle from western Canada

PubMed Central

Sánchez, Sergio; Clark, Edward G.; Wobeser, Gary A.; Janzen, Eugene D.; Philibert, Hélène

2013-01-01

Non-suppurative encephalitis occurs sporadically in beef cattle in western Canada, leading to loss of animals. This retrospective study investigated the presence of viral, bacterial, and protozoal antigens or DNA in 37 western Canadian feedlot cattle with non-suppurative encephalitis for which a cause had not been identified. Cases were selected based on the age of the animal (> 7 months), and clinical history of recumbency and depression. The identification of rabies in 1 case stresses the importance of including this viral disease in the list of differential diagnoses. Because there was variation in the severity, distribution, and type of lesions, it is possible that there may be more than 1 cause, but failure to identify an infectious agent might also suggest that non-infectious agents could play a role. PMID:24293671

Characterization of bacterial knot disease caused by Pseudomonas savastanoi pv. savastanoi on pomegranate (Punica granatum L.) trees: a new host of the pathogen.

PubMed

Bozkurt, I A; Soylu, S; Mirik, M; Ulubas Serce, C; Baysal, Ö

2014-11-01

This study aimed to isolate and identify the causal organism causing hyperplastic outgrowths (knots) on stems and branches of pomegranate trees in the Eastern Mediterranean region of Turkey. Bacterial colonies were isolated from young knots on plates containing selective nutrient media. Biochemical tests, fatty acid analysis and PCR were performed to identify possible causal disease agent. Representative isolates were identified as Pseudomonas.pv.savastanoi (Psv) using biochemical tests, fatty acid profiling and PCR. Following inoculation of pomegranate plants (cv. hicaz) with bacterial suspensions, 25 of 54 bacterial isolates caused typical knots at the site of inoculation. PCR analysis, using specific primer for Psv, generated a single amplicon from all isolates. The similarity of the sequence of Turkish pomegranate isolate was 99% similar to the corresponding gene sequences of Psv in the databases. Based on symptoms, biochemical, molecular, pathogenicity tests and sequence analyses, the disease agent of knots observed on the pomegranate trees is Psv. To the best of our knowledge, this research has revealed pomegranate as a natural host of Psv, which extends the list of host plant species affected by the pathogen in the world and Turkey. Pomegranate trees were affected by the disease with outgrowths (galls or knot) disease. Currently, there is no published study on disease agent(s) causing the galls or knots on pomegranate trees in worldwide. Bacterial colonies were isolated from young knots. The causal agent of the knot Pseudomonas savastanoi pv.savastanoi (Psv) was identified based on symptoms, biochemical, molecular methods, pathogenicity tests and sequence analysis. To the best of our knowledge, this is the first report of Psv on pomegranate as a natural host, which extends the growing list of plant species affected by this bacterium in the world and Turkey. © 2014 The Society for Applied Microbiology.

Automap User’s Guide 2013

DTIC Science & Technology

2013-06-03

dairyFarm.txt Ted runs a dairy farm. He milks the cows , runs the office, and cleans the barn. 136 dairyFarmDeleteList.txt There are some...applying the delete list, the text appears in the display like this: Ted runs dairy farm. He milks cows , runs office, cleans ...in the file. dairyFarmMeta.csv Ted,agent runs,task dairy,resource farm,location He,agent milks ,task cows ,resource office,location cleans

DETECTING SELECTION IN NATURAL POPULATIONS: MAKING SENSE OF GENOME SCANS AND TOWARDS ALTERNATIVE SOLUTIONS

PubMed Central

Haasl, Ryan J.; Payseur, Bret A.

2016-01-01

Genomewide scans for natural selection (GWSS) have become increasingly common over the last 15 years due to increased availability of genome-scale genetic data. Here, we report a representative survey of GWSS from 1999 to present and find that (i) between 1999 and 2009, 35 of 49 (71%) GWSS focused on human, while from 2010 to present, only 38 of 83 (46%) of GWSS focused on human, indicating increased focus on nonmodel organisms; (ii) the large majority of GWSS incorporate interpopulation or interspecific comparisons using, for example FST, cross-population extended haplotype homozygosity or the ratio of nonsynonymous to synonymous substitutions; (iii) most GWSS focus on detection of directional selection rather than other modes such as balancing selection; and (iv) in human GWSS, there is a clear shift after 2004 from microsatellite markers to dense SNP data. A survey of GWSS meant to identify loci positively selected in response to severe hypoxic conditions support an approach to GWSS in which a list of a priori candidate genes based on potential selective pressures are used to filter the list of significant hits a posteriori. We also discuss four frequently ignored determinants of genomic heterogeneity that complicate GWSS: mutation, recombination, selection and the genetic architecture of adaptive traits. We recommend that GWSS methodology should better incorporate aspects of genomewide heterogeneity using empirical estimates of relevant parameters and/or realistic, whole-chromosome simulations to improve interpretation of GWSS results. Finally, we argue that knowledge of potential selective agents improves interpretation of GWSS results and that new methods focused on correlations between environmental variables and genetic variation can help automate this approach. PMID:26224644

Fifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complication.

PubMed

Haasl, Ryan J; Payseur, Bret A

2016-01-01

Genomewide scans for natural selection (GWSS) have become increasingly common over the last 15 years due to increased availability of genome-scale genetic data. Here, we report a representative survey of GWSS from 1999 to present and find that (i) between 1999 and 2009, 35 of 49 (71%) GWSS focused on human, while from 2010 to present, only 38 of 83 (46%) of GWSS focused on human, indicating increased focus on nonmodel organisms; (ii) the large majority of GWSS incorporate interpopulation or interspecific comparisons using, for example F(ST), cross-population extended haplotype homozygosity or the ratio of nonsynonymous to synonymous substitutions; (iii) most GWSS focus on detection of directional selection rather than other modes such as balancing selection; and (iv) in human GWSS, there is a clear shift after 2004 from microsatellite markers to dense SNP data. A survey of GWSS meant to identify loci positively selected in response to severe hypoxic conditions support an approach to GWSS in which a list of a priori candidate genes based on potential selective pressures are used to filter the list of significant hits a posteriori. We also discuss four frequently ignored determinants of genomic heterogeneity that complicate GWSS: mutation, recombination, selection and the genetic architecture of adaptive traits. We recommend that GWSS methodology should better incorporate aspects of genomewide heterogeneity using empirical estimates of relevant parameters and/or realistic, whole-chromosome simulations to improve interpretation of GWSS results. Finally, we argue that knowledge of potential selective agents improves interpretation of GWSS results and that new methods focused on correlations between environmental variables and genetic variation can help automate this approach. © 2015 John Wiley & Sons Ltd.

Physician reasons for nonpharmacologic treatment of hyperglycemia in older patients newly diagnosed with type 2 diabetes mellitus.

PubMed

Marrett, Elizabeth; Zhang, Qiaoyi; Kanitscheider, Claudia; Davies, Michael J; Radican, Larry; Feinglos, Mark N

2012-11-01

To identify reasons why primary care physicians (PCPs) do not treat older patients newly diagnosed with type 2 diabetes mellitus (T2DM) with antihyperglycemic agents following diagnosis. US PCPs were surveyed via the internet regarding their reasons for not treating patients aged >65 years diagnosed with T2DM and had not yet initiated antihyperglycemic therapy for ≥6 months after diagnosis. PCPs were requested to provide relevant clinical information for untreated older patients and select applicable reasons for not initiating treatment from a list of 35 possibilities, grouped into five categories. A total of 508 PCPs completed the online survey and provided complete clinical data for 770 patients. The reasons provided by the first-ranked physician for not initiating antihyperglycemic therapy were related to diet and exercise (57.5%); mild hyperglycemia (23.8%); patient's concerns (13.4%); concerns about antihyperglycemic agents (3.0%); and comorbidities and polypharmacy (2.3%). The "diet and exercise" category was the most common first-ranked non-treatment reason, regardless of recent hemoglobin A(1c) (HbA(1c)) stratum. Reasons within the "patient's concerns," "concerns related to antihyperglycemic agents," and "comorbidities and polypharmacy" categories tended to be selected more often as first-ranked reasons by physicians for patients with higher HbA(1c) values. Of the 158 patients whose physicians planned to initiate antihyperglycemic therapy within the next month, 54.4% already had a most recent HbA(1c) value above their physician-stated threshold for treatment initiation. In the PCPs studied, there was a tendency to select appropriate reasons for non-treatment with antihyperglycemic agents given their patients' glycemic status. However, there was inertia related to the initiation of pharmacological therapy in some older patients with newly diagnosed T2DM. Important factors included physicians' perceptions of "mild" hyperglycemia and the HbA(1c) threshold for using antihyperglycemic agents.

21 CFR 178.3860 - Release agents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Release agents. 178.3860 Section 178.3860 Food and... and Production Aids § 178.3860 Release agents. Substances listed in paragraph (b) of this section may be safely used as release agents in petroleum wax complying with § 178.3710 and in polymeric resins...

Complexity and health professions education: a basic glossary.

PubMed

Mennin, Stewart

2010-08-01

The study of health professions education in the context of complexity science and complex adaptive systems involves different concepts and terminology that are likely to be unfamiliar to many health professions educators. A list of selected key terms and definitions from the literature of complexity science is provided to assist readers to navigate familiar territory from a different perspective. include agent, attractor, bifurcation, chaos, co-evolution, collective variable, complex adaptive systems, complexity science, deterministic systems, dynamical system, edge of chaos, emergence, equilibrium, far from equilibrium, fuzzy boundaries, linear system, non-linear system, random, self-organization and self-similarity.

The menu-setting problem and subsidized prices: drug formulary illustration.

PubMed

Olmstead, T; Zeckhauser, R

1999-10-01

The menu-setting problem (MSP) determines the goods and services an institution offers and the prices charged. It appears widely in health care, from choosing the services an insurance arrangement offers, to selecting the health plans an employer proffers. The challenge arises because purchases are subsidized, and consumers (or their physician agents) may make cost-ineffective choices. The intuitively comprehensible MSP model--readily solved by computer using actual data--helps structure thinking and support decision making about such problems. The analysis uses drug formularies--lists of approved drugs in a plan or institution--to illustrate the framework.

31 CFR 597.301 - Agent.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[FTO].” The SDN...://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to...

31 CFR 597.301 - Agent.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[FTO].” The SDN...://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to...

76 FR 30437 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

...The regulations implementing the Indian Child Welfare Act provide that Indian tribes may designate an agent other than the tribal chairman for service of notice of proceedings under the Act. This notice includes the current list of designated tribal agents for service of notice.

21 CFR 178.3010 - Adjuvant substances used in the manufacture of foamed plastics.

Code of Federal Regulations, 2011 CFR

2011-04-01

... prescribed limitations: List of substances Limitations Azodicarbonamide For use as a blowing agent in pol... agent in polystyrene. Isopentane For use as a blowing agent in polystyrene. n-Pentane Do. 1,1,2,2-Tetra-chloroethylene For use only as a blowing agent adjuvant in polystyrene at a level not to exceed 0.3 percent by...

21 CFR 178.3010 - Adjuvant substances used in the manufacture of foamed plastics.

Code of Federal Regulations, 2012 CFR

2012-04-01

... prescribed limitations: List of substances Limitations Azodicarbonamide For use as a blowing agent in pol... agent in polystyrene. Isopentane For use as a blowing agent in polystyrene. n-Pentane Do. 1,1,2,2-Tetra-chloroethylene For use only as a blowing agent adjuvant in polystyrene at a level not to exceed 0.3 percent by...

21 CFR 178.3010 - Adjuvant substances used in the manufacture of foamed plastics.

Code of Federal Regulations, 2013 CFR

2013-04-01

... prescribed limitations: List of substances Limitations Azodicarbonamide For use as a blowing agent in pol... agent in polystyrene. Isopentane For use as a blowing agent in polystyrene. n-Pentane Do. 1,1,2,2-Tetra-chloroethylene For use only as a blowing agent adjuvant in polystyrene at a level not to exceed 0.3 percent by...

BSL-3 laboratory practices in the United States: comparison of select agent and non-select agent facilities.

PubMed

Richards, Stephanie L; Pompei, Victoria C; Anderson, Alice

2014-01-01

New construction of biosafety level 3 (BSL-3) laboratories in the United States has increased in the past decade to facilitate research on potential bioterrorism agents. The Centers for Disease Control and Prevention inspect BSL-3 facilities and review commissioning documentation, but no single agency has oversight over all BSL-3 facilities. This article explores the extent to which standard operating procedures in US BSL-3 facilities vary between laboratories with select agent or non-select agent status. Comparisons are made for the following variables: personnel training, decontamination, personal protective equipment (PPE), medical surveillance, security access, laboratory structure and maintenance, funding, and pest management. Facilities working with select agents had more complex training programs and decontamination procedures than non-select agent facilities. Personnel working in select agent laboratories were likely to use powered air purifying respirators, while non-select agent laboratories primarily used N95 respirators. More rigorous medical surveillance was carried out in select agent workers (although not required by the select agent program) and a higher level of restrictive access to laboratories was found. Most select agent and non-select agent laboratories reported adequate structural integrity in facilities; however, differences were observed in personnel perception of funding for repairs. Pest management was carried out by select agent personnel more frequently than non-select agent personnel. Our findings support the need to promote high quality biosafety training and standard operating procedures in both select agent and non-select agent laboratories to improve occupational health and safety.

BSL-3 Laboratory Practices in the United States: Comparison of Select Agent and Non–Select Agent Facilities

PubMed Central

Pompei, Victoria C.; Anderson, Alice

2014-01-01

New construction of biosafety level 3 (BSL-3) laboratories in the United States has increased in the past decade to facilitate research on potential bioterrorism agents. The Centers for Disease Control and Prevention inspect BSL-3 facilities and review commissioning documentation, but no single agency has oversight over all BSL-3 facilities. This article explores the extent to which standard operating procedures in US BSL-3 facilities vary between laboratories with select agent or non–select agent status. Comparisons are made for the following variables: personnel training, decontamination, personal protective equipment (PPE), medical surveillance, security access, laboratory structure and maintenance, funding, and pest management. Facilities working with select agents had more complex training programs and decontamination procedures than non–select agent facilities. Personnel working in select agent laboratories were likely to use powered air purifying respirators, while non–select agent laboratories primarily used N95 respirators. More rigorous medical surveillance was carried out in select agent workers (although not required by the select agent program) and a higher level of restrictive access to laboratories was found. Most select agent and non–select agent laboratories reported adequate structural integrity in facilities; however, differences were observed in personnel perception of funding for repairs. Pest management was carried out by select agent personnel more frequently than non–select agent personnel. Our findings support the need to promote high quality biosafety training and standard operating procedures in both select agent and non–select agent laboratories to improve occupational health and safety. PMID:24552359

75 FR 13672 - Implementation of Both the Understandings Reached at the 2009 Australia Group (AG) Plenary...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

... under the AG intersessional silent approval procedures) to remove ``white pox'' virus from the AG ``List... pox'' virus from the AG ``List of Biological Agents for Export Control.'' Consistent with this change, this rule renumbers and/or reorders certain viruses listed in ECCN 1C351.a to conform with the format...

78 FR 8040 - National Organic Program; Proposed Amendments to the National List of Allowed and Prohibited...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

... oxidizing agent formed by a reaction of hydrogen peroxide with acetic acid in water. The reaction used to... peracetic acid. Peracetic acid is produced from the in situ reaction of acetic acid, an inert ingredient... annotation for both listings of peracetic acid.\\3\\ A second motion to list peracetic acid without any...

Prudent Use of Antimicrobials in Exotic Animal Medicine.

PubMed

Broens, Els M; van Geijlswijk, Ingeborg M

2018-05-01

Reduction of antimicrobial use can result in reduction of resistance in commensal bacteria. In exotic animals, information on use of antimicrobials and resistance in commensals and pathogens is scarce. However, use of antimicrobials listed as critically important antimicrobials for human medicine seems high in exotic animals. Ideally, the selection of a therapy should be based on an accurate diagnosis and antimicrobial susceptibility testing. When prescribing antimicrobials based on empiricism, knowledge of the most common pathogens causing specific infections and the antimicrobial spectrum of antimicrobial agents is indispensable. Implementing antimicrobial stewardship promotes the prudent use of antimicrobials in exotic animals. Copyright © 2018 Elsevier Inc. All rights reserved.

31 CFR 224.7 - Where can I find a list of United States district court offices?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

31 CFR 224.7 - Where can I find a list of United States district court offices?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

31 CFR 224.7 - Where can I find a list of United States district court offices?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

31 CFR 224.7 - Where can I find a list of United States district court offices?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE FEDERAL PROCESS AGENTS OF SURETY CORPORATIONS § 224.7 Where can I find a list of United States district...

Router Agent Technology for Policy-Based Network Management

NASA Technical Reports Server (NTRS)

Chow, Edward T.; Sudhir, Gurusham; Chang, Hsin-Ping; James, Mark; Liu, Yih-Chiao J.; Chiang, Winston

2011-01-01

This innovation can be run as a standalone network application on any computer in a networked environment. This design can be configured to control one or more routers (one instance per router), and can also be configured to listen to a policy server over the network to receive new policies based on the policy- based network management technology. The Router Agent Technology transforms the received policies into suitable Access Control List syntax for the routers it is configured to control. It commits the newly generated access control lists to the routers and provides feedback regarding any errors that were faced. The innovation also automatically generates a time-stamped log file regarding all updates to the router it is configured to control. This technology, once installed on a local network computer and started, is autonomous because it has the capability to keep listening to new policies from the policy server, transforming those policies to router-compliant access lists, and committing those access lists to a specified interface on the specified router on the network with any error feedback regarding commitment process. The stand-alone application is named RouterAgent and is currently realized as a fully functional (version 1) implementation for the Windows operating system and for CISCO routers.

Measurement of Side Effects of Drugs

PubMed Central

Huskisson, E. C.; Wojtulewski, J. A.

1974-01-01

In a clinical trial of two antirheumatic agents two methods of collection of side effects were used, one with and the other without a check list of possible symptoms. Findings suggested that the use of a check list interfered with the collection of side effects. Known side effects of aspirin—tinnitus, deafness, and gastrointestinal disturbance—were more efficiently shown and symptoms not included in the check list were more likely to be reported when a check list was not used. PMID:4853118

Successful Manipulation in Stable Marriage Model with Complete Preference Lists

NASA Astrophysics Data System (ADS)

Kobayashi, Hirotatsu; Matsui, Tomomi

This paper deals with a strategic issue in the stable marriage model with complete preference lists (i.e., a preference list of an agent is a permutation of all the members of the opposite sex). Given complete preference lists of n men over n women, and a marriage µ, we consider the problem for finding preference lists of n women over n men such that the men-proposing deferred acceptance algorithm (Gale-Shapley algorithm) adopted to the lists produces µ. We show a simple necessary and sufficient condition for the existence of a set of preference lists of women over men. Our condition directly gives an O(n2) time algorithm for finding a set of preference lists, if it exists.

77 FR 2561 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-18

... use by masters, owners, or agents of vessels in complying with Sections 231 and 251 of the Immigration... I-418 can be found at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf . Current Actions: This submission...

76 FR 9806 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

..., owners, or agents of vessels in complying with Sections 231 and 251 of the Immigration and Nationality... can be found at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf . Current Actions: This submission is being...

Pharmacist-managed inpatient discharge medication reconciliation: a combined onsite and telepharmacy model.

PubMed

Keeys, Christopher; Kalejaiye, Bamidele; Skinner, Michelle; Eimen, Mandana; Neufer, Joann; Sidbury, Gisele; Buster, Norman; Vincent, Joan

2014-12-15

The development, implementation, and pilot testing of a discharge medication reconciliation service managed by pharmacists with offsite telepharmacy support are described. Hospitals' efforts to prepare legible, complete, and accurate medication lists to patients prior to discharge continue to be complicated by staffing and time constraints and suboptimal information technology. To address these challenges, the pharmacy department at a 324-bed community hospital initiated a quality-improvement project to optimize patients' discharge medication lists while addressing problems that often resulted in confusing, incomplete, or inaccurate lists. A subcommittee of the hospital's pharmacy and therapeutics committee led the development of a revised medication reconciliation process designed to streamline and improve the accuracy and utility of discharge medication documents, with subsequent implementation of a new service model encompassing both onsite and remote pharmacists. The new process and service were evaluated on selected patient care units in a 19-month pilot project requiring collaboration by physicians, nurses, case managers, pharmacists, and an outpatient prescription drug database vendor. During the pilot testing period, 6402 comprehensive reconciled discharge medication lists were prepared; 634 documented discrepancies or medication errors were detected. The majority of identified problems were in three categories: unreconciled medication orders (31%), order clarification (25%), and duplicate orders (12%). The most problematic medications were the opioids, cardiovascular agents, and anticoagulants. A pharmacist-managed medication reconciliation service including onsite pharmacists and telepharmacy support was successful in improving the final discharge lists and documentation received by patients. Copyright © 2014 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

42 CFR 73.11 - Security.

Code of Federal Regulations, 2010 CFR

2010-10-01

... select agent or toxin against unauthorized access, theft, loss, or release. (b) The security plan must be... activities, loss or theft of select agents or toxins, release of select agents or toxins, or alteration of... of select agents or toxins, (iv) Any release of a select agent or toxin, and (v) Any sign that...

9 CFR 121.11 - Security.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the select agent or toxin against unauthorized access, theft, loss, or release. (b) The security plan... activities, loss or theft of select agents or toxins, release of select agents or toxins, or alteration of... of select agents or toxins; (iv) Any release of a select agent or toxin; and (v) Any sign that...

Pseudomonas fluorescens SBW25 produces furanomycin, a non-proteinogenic amino acid with selective antimicrobial properties.

PubMed

Trippe, Kristin; McPhail, Kerry; Armstrong, Donald; Azevedo, Mark; Banowetz, Gary

2013-05-20

Pseudomonas fluorescens SBW25 has been extensively studied because of its plant growth promoting properties and potential as a biocontrol agent. The genome of SBW25 has been sequenced, and among sequenced strains of pseudomonads, SBW25 appears to be most closely related to P. fluorescens WH6. In the authors' laboratories, WH6 was previously shown to produce and secrete 4-formylaminooxyvinylglycine (FVG), a non-proteinogenic amino acid with selective herbicidal and antimicrobial activity. Although SBW25 does not have the genetic capacity to produce FVG, we were interested in determining whether this pseudomonad might produce some other type of non-proteinogenic amino acid. P. fluorescens SBW25 was found to produce and secrete a ninhydrin-reactive compound with selective antimicrobial properties. This compound was purified from SBW25 culture filtrate and identified as the non-proteinogenic amino acid L-furanomycin [2S,2'R,5'S)-2-amino-2-(5'methyl-2',5'-dihydrofuran-2'-yl)acetic acid]. The identification of furanomycin as a secondary metabolite of SBW25 is the first report of the production of furanomycin by a pseudomonad. This compound was known previously only as a natural product produced by a strain of Streptomyces. This report adds furanomycin to the small list of non-proteinogenic amino acids that have been identified as secondary products of pseudomonads. This study also extends the list of bacteria that are inhibited by furanomycin to include several plant pathogenic bacteria.

76 FR 62412 - Agency Forms Undergoing Paperwork Reduction Act Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-07

... for Registration, (2) Request to Transfer Select Agent or Toxin, (3) Report of Theft, Loss, or Release..., or Release of Select Agent and Toxin, (4) Report of Identification of Select Agent or Toxin. There... Release of Select Agent or Toxin; (4) Report of Identification of Select Agent or Toxin; and (5) Request...

Antidiabetic Agents.

ERIC Educational Resources Information Center

Plummer, Nancy; Michael, Nancy, Ed.

This module on antidiabetic agents is intended for use in inservice or continuing education programs for persons who administer medications in long-term care facilities. Instructor information, including teaching suggestions, and a listing of recommended audiovisual materials and their sources appear first. The module goal and objectives are then…

49 CFR 1002.2 - Filing fees.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., by check payable in United States currency drawn upon funds deposited in a United States or foreign bank or other financial institution, money order payable in United States currency, or by credit card..., agent $32 per delivery. (97) Request for service or pleading list for proceedings $24 per list. (98...

9 CFR 121.4 - Overlap select agents and toxins.

Code of Federal Regulations, 2012 CFR

2012-01-01

... select agent or toxin to APHIS or CDC. (i) The seizure of any of the following overlap select agents and.... This report must be followed by submission of APHIS/CDC Form 4 within 7 calendar days after seizure of the overlap select agent or toxin. (ii) For all other overlap select agents or toxins, APHIS/CDC Form...

Selected list of Books and Journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1983-01-01

The relationship of the "Selected List" to collection development is explored in the introduction to this revised list of 559 books and 135 journals. The list is intended as a selection guide for the small or medium-sized library in a hospital or comparable medical facility or as a core collection for a consortium of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries (155 books and 54 journals) are indicated by asterisks. To purchase the entire collection of books and to pay for annual subscriptions would require an expenditure of about $38,900. The cost of only the asterisked items totals approximately $13,200. PMID:6190523

7 CFR 905.120 - Nomination procedure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ORANGES, GRAPEFRUIT, TANGERINES... be delivered by the chairman or the secretary of the meeting to the agent of the Secretary. If ballots are not used, the committee's representative shall deliver to the Secretary's agent a listing of...

21 CFR 807.40 - Establishment registration and device listing for foreign establishments importing or offering...

Code of Federal Regulations, 2014 CFR

2014-04-01

... paragraph (a) of this section shall submit the name, address, and phone number of its United States agent as... changes in the United States agent's name, address, or phone number to FDA within 10-business days of the...

21 CFR 807.40 - Establishment registration and device listing for foreign establishments importing or offering...

Code of Federal Regulations, 2013 CFR

2013-04-01

... paragraph (a) of this section shall submit the name, address, and phone number of its United States agent as... changes in the United States agent's name, address, or phone number to FDA within 10-business days of the...

Effects of antimicrobial treatment on fiberglass-acrylic filters.

PubMed

Cecchini, C; Verdenelli, M C; Orpianesi, C; Dadea, G M; Cresci, A

2004-01-01

The aims of the present study were to: (i) analyse a group of antimicrobial agents and to select the most active against test microbial strains; (ii) test the effect of the antimicrobial treatment on air filters in order to reduce microbial colonization. Different kinds of antimicrobial agents were analysed to assess their compatibility with the production process of air filter media. The minimal inhibitory concentration for each antimicrobial agent was determined against a defined list of microbial strains, and an antimicrobial activity assay of filter prototypes was developed to determine the most active agent among the compatible antimicrobials. Then, the most active was chosen and added directly to the filter during the production process. The microbial colonization of treated and untreated filter media was assessed at different working times for different incubation times by stereomicroscope and scanning electron microscope analysis. Some of the antimicrobial agents analysed were more active against microbial test strains and compatible with the production process of the filter media. Filter sections analysis of treated filter media showed a significantly lower microbial colonization than those untreated, a reduction of species both in density and varieties and of the presence of bacteria and fungal hyphae with reproductive structures. This study demonstrated the ability of antimicrobial treatments to inhibit the growth of micro-organisms in filter media and subsequently to increase indoor air quality (IAQ), highlighting the value of adding antimicrobials to filter media. To make a contribution to solving the problem of microbial contamination of air filters, by demonstrating the efficacy of incorporating antimicrobial agents in the filter media to improve IAQ and health.

[Sleep disorders and impaired sleep as adverse drug reactions of psychotropic drugs: an evaluation of data of summaries of product characteristics].

PubMed

Gahr, Maximilian; Connemann, Bernhard J; Zeiss, René; Fröhlich, Albrecht

2018-03-02

 Psychopharmacotherapy is essential in the treatment of many mental disorders. Adverse drug reactions (ADR) have impact on compliance and tolerability. Sleep disorders or impaired sleep may occur as ADRs of psychopharmacotherapy. Sleep disorders are associated with an increased risk for physical and mental illness and may impair cognition, impulse control, emotion regulation and mood. Objective of the following study was the systematic presentation of type and risk of sleep disorders/impairments of sleep of frequently prescribed psychotropic drugs.  Psychotropic agents that are most frequently prescribed in Germany were identified by using the Arzneiverordnungs-Report 2016. Summaries of product characteristics (SmPC) of corresponding original products were analyzed regarding presence and frequency of sleep disorders/impairments of sleep according to the International Classification of Sleep Disorders 3 (ICSD-3).  N = 64 SmPCs were analyzed. In most of the analyzed SmPCs, at least one sleep disorder (50/64; 78 %) was listed. At least one SmPC with a corresponding ADR was found in the categories insomnia (52 %), parasomnias (33 %), and sleep-related movement disorders (20 %); sleep-related breathing disorders (6 %) and central disorders of hypersomnolence (5 %) were rarely listed; circadian rhythm sleep-wake disorder was not found. The SmPCs of the four most frequently prescribed agents (citalopram > venlafaxine > mirtazapine > sertraline) listed insomnia as an ADR. Nearly all analysed hypnotics (except chloral hydrate) were associated with nightmares.  Most of the psychotropic agents frequently prescribed in Germany may induce sleep disorders/impairments of sleep. The four most frequently prescribed agents were antidepressants and all of the corresponding SmPCs listed insomnia as a possible ADR. Sleep disorders should be taken seriously as possible ADRs of psychopharmacotherapy. © Georg Thieme Verlag KG Stuttgart · New York.

77 FR 71702 - Possession, Use, and Transfer of Select Agents and Toxins; Biennial Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-04

... of Select Agents and Toxins; Biennial Review AGENCY: Centers for Disease Control and Prevention (CDC... designated certain select agents and toxins as Tier 1 agents. DATES: Effective Date: Effective December 4, 2012. FOR FURTHER INFORMATION CONTACT: Robbin Weyant, Director, Division of Select Agents and Toxins...

75 FR 28103 - Indian Child Welfare Act; Designated Tribal Agents for Service of Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-19

...The regulations implementing the Indian Child Welfare Act provide that Indian Tribes may designate an agent other than the Tribal chairman for service of notice of proceedings under the Act. This notice includes the current list of designated Tribal agents for service of notice. The names are those received by the Secretary of the Interior before the date of this publication.

2000 Honor List: A Hopeful Bunch.

ERIC Educational Resources Information Center

Nilsen, Alleen Pace; Donelson, Ken; Blasingame, James, Jr.

2001-01-01

Presents 11 titles selected for the 2000 Honor List for young adult literature. Notes that the books were selected by combining their favorites with the best-book list compiled by the editors of such publications as "School Library Journal,""Booklist," and "Horn Book." (SG)

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1985-01-01

The interrelationship of print and electronic media in the hospital library and the relevance of the "Selected List" in 1985 are discussed in the introduction to this revised list of 583 books and 138 journals. The list is meant to be a selection guide for the small or medium-size library in a hospital or comparable medical facility, or a core collection for a consortium of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by asterisks. To purchase the entire collection of books and to pay for 1985 subscriptions to all the journals would require about $45,200. The cost of only the asterisked items totals approximately $16,100. PMID:3888331

Listing Occupational Carcinogens

PubMed Central

Siemiatycki, Jack; Richardson, Lesley; Straif, Kurt; Latreille, Benoit; Lakhani, Ramzan; Campbell, Sally; Rousseau, Marie-Claude; Boffetta, Paolo

2004-01-01

The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens. There is a large volume of epidemiologic and experimental data concerning cancer risks in different work environments. It is important to synthesize this information for both scientific and public health purposes. Various organizations and individuals have published lists of occupational carcinogens. However, such lists have been limited by unclear criteria for which recognized carcinogens should be considered occupational carcinogens, and by inconsistent and incomplete information on the occupations and industries in which the carcinogenic substances may be found and on their target sites of cancer. Based largely on the evaluations published by the International Agency for Research on Cancer, and augmented with additional information, the present article represents an attempt to summarize, in tabular form, current knowledge on occupational carcinogens, the occupations and industries in which they are found, and their target organs. We have considered 28 agents as definite occupational carcinogens, 27 agents as probable occupational carcinogens, and 113 agents as possible occupational carcinogens. These tables should be useful for regulatory or preventive purposes and for scientific purposes in research priority setting and in understanding carcinogenesis. PMID:15531427

49 CFR 176.30 - Dangerous cargo manifest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... purpose by the carrier or agents shall prepare a dangerous cargo manifest, list, or stowage plan. This... number as prescribed in subpart G of part 172 of this subchapter. (4) The number and description of... paragraphs (a)(3) and (a)(5) of this section. The person who supervises the preparation of the manifest, list...

The Business Education Index 1996. Index of Business Education Articles and Research Studies Compiled from a Selected List of Periodicals Published during the Year 1996. Volume 57.

ERIC Educational Resources Information Center

Noll, Cheryl L., Ed.; Graves, Pat R., Ed.

This index, which was compiled from a selected list of 45 periodicals published in 1996, lists more than 2,000 business education articles and research studies. Articles are listed under the following subject categories and subcategories: basic business (accounting, consumer awareness, economics, entrepreneurship/small business, finance…

Limited-sampling strategies for anti-infective agents: systematic review.

PubMed

Sprague, Denise A; Ensom, Mary H H

2009-09-01

Area under the concentration-time curve (AUC) is a pharmacokinetic parameter that represents overall exposure to a drug. For selected anti-infective agents, pharmacokinetic-pharmacodynamic parameters, such as AUC/MIC (where MIC is the minimal inhibitory concentration), have been correlated with outcome in a few studies. A limited-sampling strategy may be used to estimate pharmacokinetic parameters such as AUC, without the frequent, costly, and inconvenient blood sampling that would be required to directly calculate the AUC. To discuss, by means of a systematic review, the strengths, limitations, and clinical implications of published studies involving a limited-sampling strategy for anti-infective agents and to propose improvements in methodology for future studies. The PubMed and EMBASE databases were searched using the terms "anti-infective agents", "limited sampling", "optimal sampling", "sparse sampling", "AUC monitoring", "abbreviated AUC", "abbreviated sampling", and "Bayesian". The reference lists of retrieved articles were searched manually. Included studies were classified according to modified criteria from the US Preventive Services Task Force. Twenty studies met the inclusion criteria. Six of the studies (involving didanosine, zidovudine, nevirapine, ciprofloxacin, efavirenz, and nelfinavir) were classified as providing level I evidence, 4 studies (involving vancomycin, didanosine, lamivudine, and lopinavir-ritonavir) provided level II-1 evidence, 2 studies (involving saquinavir and ceftazidime) provided level II-2 evidence, and 8 studies (involving ciprofloxacin, nelfinavir, vancomycin, ceftazidime, ganciclovir, pyrazinamide, meropenem, and alpha interferon) provided level III evidence. All of the studies providing level I evidence used prospectively collected data and proper validation procedures with separate, randomly selected index and validation groups. However, most of the included studies did not provide an adequate description of the methods or the characteristics of included patients, which limited their generalizability. Many limited-sampling strategies have been developed for anti-infective agents that do not have a clearly established link between AUC and clinical outcomes in humans. Future studies should first determine if there is an association between AUC monitoring and clinical outcomes. Thereafter, it may be worthwhile to prospectively develop and validate a limited-sampling strategy for the particular anti-infective agent in a similar population.

Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high resolution/high accuracy mass spectrometry.

PubMed

Görgens, Christian; Guddat, Sven; Thomas, Andreas; Wachsmuth, Philipp; Orlovius, Anne-Katrin; Sigmund, Gerd; Thevis, Mario; Schänzer, Wilhelm

2016-11-30

So far, in sports drug testing compounds of different classes are processed and measured using different screening procedures. The constantly increasing number of samples in doping analysis, as well as the large number of substances with doping related, pharmacological effects require the development of even more powerful assays than those already employed in sports drug testing, indispensably with reduced sample preparation procedures. The analysis of native urine samples after direct injection provides a promising analytical approach, which thereby possesses a broad applicability to many different compounds and their metabolites, without a time-consuming sample preparation. In this study, a novel multi-target approach based on liquid chromatography and high resolution/high accuracy mass spectrometry is presented to screen for more than 200 analytes of various classes of doping agents far below the required detection limits in sports drug testing. Here, classic groups of drugs as diuretics, stimulants, β 2 -agonists, narcotics and anabolic androgenic steroids as well as various newer target compounds like hypoxia-inducible factor (HIF) stabilizers, selective androgen receptor modulators (SARMs), selective estrogen receptor modulators (SERMs), plasma volume expanders and other doping related compounds, listed in the 2016 WADA prohibited list were implemented. As a main achievement, growth hormone releasing peptides could be implemented, which chemically belong to the group of small peptides (<2kDa) and are commonly determined by laborious and time-consuming stand-alone assays. The assay was fully validated for qualitative purposes considering the parameters specificity, robustness (rRT: <2%), intra- (CV: 1.7-18.4 %) and inter-day precision (CV: 2.3-18.3%) at three concentration levels, linearity (R 2 >0.99), limit of detection (0.1-25ng/mL; 3'OH-stanozolol glucuronide: 50pg/mL; dextran/HES: 10μg/mL) and matrix effects. Copyright © 2016 Elsevier B.V. All rights reserved.

78 FR 66973 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... the administrator, accountant, custodian and transfer agent for the Fund (``Administrator,'' ``Accountant,'' ``Custodian'' and ``Transfer Agent,'' respectively). \\4\\ A Managed Fund Share is a security... expenses, dividends, distributions, taxes, risks, and reports to be distributed to beneficial owners of the...

21 CFR 178.3400 - Emulsifiers and/or surface-active agents.

Code of Federal Regulations, 2014 CFR

2014-04-01

... paperboard. α-[p-(1,1,3,3-Tetramethylbutyl)phenyl] omega-hydroxypoly(oxyethylene) produced by the... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Emulsifiers and/or surface-active agents. 178.3400... substances: List of substances Limitations α-Alkyl-, α-alkenyl-, and α-alkylaryl-omega-hydroxypoly...

Effective Coordination of Multiple Intelligent Agents for Command and Control

DTIC Science & Technology

2003-09-01

System Architecture As an initial problem domain in E - commerce , we chose collective book purchasing. In the university setting, relatively large numbers... a coalition server, an auctioneer agent, a set of supplier agents, and a web- based interface 9 for end users. The system is based on a simple...buyers are able to request and sellers to respond to a list of items, within a particular category. Sellers present

Dental cements for definitive luting: a review and practical clinical considerations.

PubMed

Hill, Edward E

2007-07-01

Dental cement used to attach an indirect restoration to a prepared tooth is called a luting agent. A clinically relevant discussion of conventional and contemporary definitive luting agents is presented in this article. Physical properties are listed in table form to assist in comparison and decision-making. Additional subtopics include luting agent requirements, classifications, retention and bonding, cement considerations for implant-supported teeth, and fatigue failure.

A Selected List of Business and Economic Sources. Bibliographic Series No. 27.

ERIC Educational Resources Information Center

Ahrens, Joan

Selected information sources in business and economics held by the Arkansas University library are listed. Items are organized by material type, including indexes, directories, atlases, bibliographies, dictionaries, encyclopedias, guides, handbooks, and newspapers. Separate listings of Moody's and Standard and Poor's looseleaf publications are…

Libraries & Study Facilities. A Selected Bibliography.

ERIC Educational Resources Information Center

Wisconsin Univ., Madison. ERIC Clearinghouse on Educational Facilities.

This bibliography contains a selected reference list of publications of interest to architects, library planners, and librarians contemplating the planning, programing, and/or design of library facilities. Each reference is followed by a listing of ERIC descriptors that describe its contents. The items are listed in six sections: (1) library…

77 FR 28408 - Product List Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

... POSTAL REGULATORY COMMISSION [Docket No. MC2012-16 and CP2012-23; Order No. 1335] Product List... noticing a recently-filed Postal Service request to add Parcel Select Contract 2 to the competitive product... associated supporting information to add Parcel Select Contract 1 to the competitive product list.\\1\\ The...

Selection and a 3-Year Field Trial of Sorangium cellulosum KYC 3262 Against Anthracnose in Hot Pepper

PubMed Central

Yun, Sung-Chul

2014-01-01

KYC 3262 was selected as a biocontrol agent against anthracnose on hot pepper from 813 extracts of myxobacterial isolates. Dual culture with Colletotrichum acutatum and 813 myxobacterial extracts was conducted, and 19 extracts were selected that inhibited germination and mycelial growth of C. acutatum. All selections were Sorangium cellulosum, which are cellulolytic myxobacteria from soil. With the infection bioassay on detached fruits in airtight containers, KYC 3262, KYC 3512, KYC 3279, and KYC 3584 were selected. The listed four myxobacteria were cultured in CSG/1 liquid media, and harvested filtrates were sprayed on the infected fruits. KYC 3262 was selected from the studies of attached fruit in a greenhouse study. KYC 3262 filtrate was applied for 3 years (from 2011 to 2013) in a field study in Asan, Republic of Korea. Control values of the KYC 3262 in the field were 31%, 89%, and 82% in 2011, 2012, and 2013, whereas values of the fungicide spray treatment were 19%, 97%, and 91%, respectively. Yields (kg/20 plants) of the KYC 3262 were 2.66 kg and 18.6 kg in 2011 and 2013, respectively, and those of the fungicide treatment were 2.0 kg and 20.2 kg, in 2011 and 2013, respectively. PMID:25289014

Circulation of core collection monographs in an academic medical library.

PubMed

Schmidt, C M; Eckerman, N L

2001-04-01

Academic medical librarians responsible for monograph acquisition face a challenging task. From the plethora of medical monographs published each year, academic medical librarians must select those most useful to their patrons. Unfortunately, none of the selection tools available to medical librarians are specifically intended to assist academic librarians with medical monograph selection. The few short core collection lists that are available are intended for use in the small hospital or internal medicine department library. As these are the only selection tools available, however, many academic medical librarians spend considerable time reviewing these collection lists and place heavy emphasis on the acquisition of listed books. The study reported here was initiated to determine whether the circulation of listed books in an academic library justified the emphasis placed on the acquisition of these books. Circulation statistics for "listed" and "nonlisted" books in the hematology (WH) section of Indiana University School of Medicine's Ruth Lilly Medical Library were studied. The average circulation figures for listed books were nearly two times as high as the corresponding figures for the WH books in general. These data support the policies of those academic medical libraries that place a high priority on collection of listed books.

15 CFR 752.3 - Eligible items.

Code of Federal Regulations, 2010 CFR

2010-01-01

... “Reason for Control” paragraph on the Commerce Control List (CCL) (see Supplement No. 1 to part 774 of the... chemical warfare agents, to destinations listed in Country Group D:3 (see Supplement No. 1 to part 740 of... applicable “Reason for Control” paragraph on the CCL; (5) Items controlled for EI reasons on the CCL; (6...

76 FR 30092 - Notice of Request for Extension of Approval of an Information Collection; Select Agent Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

...] Notice of Request for Extension of Approval of an Information Collection; Select Agent Registration... . FOR FURTHER INFORMATION CONTACT: For information regarding the select agent registration process... Dr. Charles Divan, Branch Chief, Agriculture Select Agent Program, RIPPS, PPQ, APHIS, 4700 River Road...

75 FR 23223 - Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-03

...] Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program; Public... Select Agent Program established under the Public Health Security and Bioterrorism Preparedness and... Roberson, Veterinary Permit Examiner, APHIS Select Agent Program, VS, ASAP, APHIS, 4700 River Road Unit 2...

76 FR 14896 - Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

...] Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program; Public... specific regulatory guidance related to the Federal Select Agent Program established under the Public.... Sarah Kwiatkowski, Veterinary Program Assistant, APHIS Select Agent Program, APHIS, 4700 River Road Unit...

76 FR 17617 - Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-30

...] Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program; Public... specific regulatory guidance related to the Federal Select Agent Program established under the Public.... Sarah Kwiatkowski, Veterinary Program Assistant, APHIS Select Agent Program, APHIS, 4700 River Road Unit...

77 FR 56845 - Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Informational Meeting Concerning Compliance With the Federal Select Agent Program; Public Webcast AGENCY... with the Federal Select Agent Program. The purpose of this notice is to notify all interested parties... changes to the select agent regulations; occupational health, information and physical security; personnel...

78 FR 56234 - Multi-Agency Informational Meeting Concerning Compliance with the Select Agent Regulations...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... Informational Meeting Concerning Compliance with the Select Agent Regulations; Public Webcast AGENCY: Centers... purpose of the webcast is to provide guidance related to the select agent regulations established under... Justice Information Services. Changes to Section 11(Security) of the select agent regulations including...

Brandon/Hill selected list of books and journals for the small medical library.

PubMed

Hill, D R

1999-04-01

The interrelationship of print and electronic media in the hospital library and its relevance to the "Brandon/Hill Selected List" in 1999 are addressed in the updated list (eighteenth version) of 627 books and 145 journals. This list is intended as a selection guide for the small or medium-size library in a hospital or similar facility. More realistically, it can function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Due to continuing requests from librarians, a "minimal core" book collection consisting of 82 titles has been pulled out from the 214 asterisked (*) initial-purchase books and marked with daggers ([symbol: see text]). To purchase the entire collection of books and to pay for 1999 journal subscriptions would require $114,900. The cost of only the asterisked items, books and journals, totals $49,100. The "minimal core" book collection costs $13,200.

Brandon/Hill selected list of print books and journals for the small medical library.

PubMed

Hill, D R; Stickell, H N

2001-04-01

After thirty-six years of biennial updates, the authors take great pride in being able to publish the nineteenth version (2001) of the "Brandon/Hill Selected List of Print Books and Journals for the Small Medical Library." This list of 630 books and 143 journals is intended as a selection guide for health sciences libraries or similar facilities. It can also function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals, by an alphabetical title listing. Due to continuing requests from librarians, a "minimal core list" consisting of 81 titles has been pulled out from the 217 asterisked (*) initial-purchase books and marked with daggers (dagger *) before the asterisks. To purchase the entire collection of 630 books and to pay for 143 2001 journal subscriptions would require $124,000. The cost of only the asterisked items, books and journals, totals $55,000. The "minimal core list" book collection costs approximately $14,300.

49 CFR 176.30 - Dangerous cargo manifest.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Dangerous cargo manifest. 176.30 Section 176.30... Requirements § 176.30 Dangerous cargo manifest. (a) The carrier, its agents, and any person designated for this purpose by the carrier or agents shall prepare a dangerous cargo manifest, list, or stowage plan. This...

49 CFR 176.30 - Dangerous cargo manifest.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Dangerous cargo manifest. 176.30 Section 176.30... Requirements § 176.30 Dangerous cargo manifest. (a) The carrier, its agents, and any person designated for this purpose by the carrier or agents must prepare a dangerous cargo manifest, list, or stowage plan. This...

49 CFR 176.30 - Dangerous cargo manifest.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Dangerous cargo manifest. 176.30 Section 176.30... Requirements § 176.30 Dangerous cargo manifest. (a) The carrier, its agents, and any person designated for this purpose by the carrier or agents shall prepare a dangerous cargo manifest, list, or stowage plan. This...

49 CFR 176.30 - Dangerous cargo manifest.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Dangerous cargo manifest. 176.30 Section 176.30... Requirements § 176.30 Dangerous cargo manifest. (a) The carrier, its agents, and any person designated for this purpose by the carrier or agents must prepare a dangerous cargo manifest, list, or stowage plan. This...

46 CFR 109.415 - Retention of records after casualty.

Code of Federal Regulations, 2010 CFR

2010-10-01

... casualty. (a) The owner, agent, master, or person in charge of a unit for which a report of casualty is... of casualty. (6) Navigation work books. (7) Compass deviation cards. (8) Gyrocompass records. (9...) The radio log. (14) Personnel list. (15) Crane record book. (c) The owner, agent, master, or person in...

Report of the Subcommittee for Travel/Tourism of the Hospitality/Tourism/Recreation Technical Committee.

ERIC Educational Resources Information Center

Oregon State Dept. of Education, Salem. Div. of Vocational Education.

Written by a technical committee's industry representatives, state officials, and educators in Oregon, this document lists the skills and knowledge required by employees in travel and tourism occupations. The following occupations are considered: rental representative; service agent; travel agent; bus/tour/driver/guide/sightseeing leader; manager…

31 CFR 103.41 - Registration of money services businesses.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-year period beginning with the calendar year in which the money services business is first required to... maintaining the list, whether in the agent's or the business principal's name; (G) The year in which the agent... businesses. 103.41 Section 103.41 Money and Finance: Treasury Regulations Relating to Money and Finance...

Questioning the Validity of a State Reading List

ERIC Educational Resources Information Center

Berridge, Gina; Thomas, Jeff

2013-01-01

Quality incorporation of children's literature has long been supported to help students learn. The purpose of this study was to examine the 79 fiction selections of our state's sponsored reading list for grades K-2. The list was examined for original publication date, selections recognized as award winners, sex of authors, sex of protagonist, race…

Selected List of Books and Journals for the Small Medical Library

PubMed Central

Brandon, Alfred N.

1965-01-01

This list of 358 books and 123 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. PMID:14308899

Higher Education Opportunities for Minorities and Women--Annotated Selections. 1989 Edition.

ERIC Educational Resources Information Center

Young, William C., Comp.; Hicks, Edward L., Comp.

Developed to assist parents and students in finding sources of postsecondary financial aid, this annotated listing provides a brief summary of the basic information about a selected list of financial aid sources designed primarily for minority groups and women, or available to all students. The listings provide names and addresses, background…

Selected List of Books and Journals for the Small Medical Library

PubMed Central

Brandon, Alfred N.

2012-01-01

This list of 358 books and 123 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. PMID:23509428

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N

1967-04-01

This updated list of 388 books and 140 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing.

SELECTED LIST OF BOOKS AND JOURNALS FOR THE SMALL MEDICAL LIBRARY.

PubMed

BRANDON, A N

1965-07-01

This list of 358 books and 123 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing.

Datalist: A Value Added Service to Enable Easy Data Selection

NASA Technical Reports Server (NTRS)

Li, Angela; Hegde, Mahabaleshwa; Bryant, Keith; Seiler, Edward; Shie, Chung-Lin; Teng, William; Liu, Zhong; Hearty, Thomas; Shen, Suhung; Kempler, Steven;

76 FR 62312 - Multi-Agency Informational Meeting Concerning Compliance With the Federal Select Agent Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-07

... Select Agent Program; Public Meeting AGENCIES: Animal and Plant Health Inspection Service, USDA. ACTION... will be held to provide specific regulatory guidance related to the Federal Select Agent Program... Select Agent Program, APHIS, 4700 River Road, Unit 2, Riverdale, MD 20737; (301) 734-5960. CDC: Dr...

Variable stars around selected open clusters in the VVV area: Young Stellar Objects

NASA Astrophysics Data System (ADS)

Medina, Nicolas; Borissova, Jura; Bayo, Amelia; Kurtev, Radostin; Lucas, Philip

2017-09-01

Time-varying phenomena are one of the most substantial sources of astrophysical information, and led to many fundamental discoveries in modern astronomy. We have developed an automated tool to search and analyze variable sources in the near infrared Ks band, using the data from the Vista Variables in the Vía Láctea (VVV) ESO Public Survey ([5, 8]). One of our main goals is to investigate the Young Stellar Objects (YSOs) in the Galactic star forming regions, looking for: •Variability. •New pre-main sequence star clusters. Here we present the newly discovered YSOs within some selected stellar clusters in our Galaxy.

9 CFR 205.208 - Distribution of portions of master list-registration-information to non-registrants on request.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Distribution of portions of master....208 Distribution of portions of master list—registration—information to non-registrants on request. (a..., and selling agents,” “regular” distribution of “portions” of the master list, furnishing of “oral...

9 CFR 205.208 - Distribution of portions of master list-registration-information to non-registrants on request.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Distribution of portions of master....208 Distribution of portions of master list—registration—information to non-registrants on request. (a..., and selling agents,” “regular” distribution of “portions” of the master list, furnishing of “oral...

9 CFR 205.208 - Distribution of portions of master list-registration-information to non-registrants on request.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Distribution of portions of master....208 Distribution of portions of master list—registration—information to non-registrants on request. (a..., and selling agents,” “regular” distribution of “portions” of the master list, furnishing of “oral...

9 CFR 205.208 - Distribution of portions of master list-registration-information to non-registrants on request.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Distribution of portions of master....208 Distribution of portions of master list—registration—information to non-registrants on request. (a..., and selling agents,” “regular” distribution of “portions” of the master list, furnishing of “oral...

75 FR 20651 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-20

... Proposed Rule Change To Amend the Global Select Market Initial Listing Requirements April 14, 2010... the Global Select initial listing requirements and to make a technical conforming correction to a rule...'s market capitalization at the time of listing. (f)-(h) No change. (i) A Company whose business plan...

American Folk Music and Folklore Recordings 1983: A Selected List.

ERIC Educational Resources Information Center

Library of Congress, Washington, DC. American Folklife Center.

Recognizing the need to inform the public about newly issued folk recordings and audio tapes, the American Folklife Center of the Library of Congress initiates this annual list of selected titles, chosen by a panel of distinguished experts from a compilation of 1983 releases prepared by the Center staff. Although not a comprehensive list, it is…

Selected List of Books and Journals for the Small Medical Library *

PubMed Central

Brandon, Alfred N.

1967-01-01

This updated list of 388 books and 140 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. PMID:6041826

The role of ion optics modeling in the design and development of ion mobility spectrometers

NASA Astrophysics Data System (ADS)

Griffin, Matthew T.

2005-05-01

Detection of trace gases by ion mobility spectroscopy (IMS) has become common in recent years. In fact, IMS devices are the most commonly deployed military devices for the detection of classical chemical warfare agents (CWA). IMS devices are protecting the homeland by aiding first responders in the identification of toxic industrial chemicals (TICs) and providing explosive and narcotic screening systems. Spurred by the asymmetric threat posed by new threat agents and the ever expanding list of toxic chemicals, research in the development, improvement, and optimization of IMS systems has increased. Much of the research is focused on increasing the sensitivity and selectivity of IMS systems. Ion optics is a large area of study in the field of mass spectrometry, but has been mostly overlooked in the design and development of IMS systems. Ion optics provides insight into particle trajectories, duty cycle, and efficiency of these systems. This paper will outline the role that ion optics can have in the development of IMS systems and introduce the trade space for traditional IMS as well as differential mobility spectroscopy.

Uso del Registro de Solicitudes de Medicamentos no Incluidos en el Listado de Medicamentos Esenciales como Nueva Fuente de Información en los Sistemas Nacionales de Farmacovigilancia.

PubMed

Buendía, Jefferson Antonio; Zuluaga Salazar, Andrés Felipe; Vacca González, Claudia Patricia

2013-12-01

To describe the frequency of adverse drugs events (ADEs) as possible causes of request of drugs not included in national essential Medicines list in Colombia. This was a descriptive study developed in a private medical insurance company in Bogota, Colombia. Data were obtained from drug request form of drugs not included in a national essential Medicines list. We analyzed the content of the notes to identify the records related to the occurrence of ADEs in the period 2008 to 2009. Information concerning the adverse event and the drug involved was recorded in a data collection instrument developed by the researchers. The pharmacological classification of drugs was performed according to the Anatomical Therapeutic Chemical Classification System (ATC). We study 3,336 request forms of drugs not included in a national essential Medicines list. The level 1 groups of the ATC of drugs with greater frequency of ADEs were the cardiovascular agents (47%), nervous system agents (24%) and antineoplastic and immunomodulating agents (15%). The great majority was cases of light severity (62.7%) and classified as possible (48.4%). The results of this study support the innovative approach of using request form of drug not included in national essential Medicines list to obtain information regarding ADEs in developing countries; recognizing the importance of looking for new sources of report of adverse reactions to diminish the under-notification of ADEs. © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Published by International Society for Pharmacoeconomics and Outcomes Research (ISPOR) All rights reserved.

Sickle Cell: A Selected Resource Bibliography.

ERIC Educational Resources Information Center

National Center for Education in Maternal and Child Health, Washington, DC.

This annotated, selective bibliography lists the following types of educational and informational material on both sickle cell disease and trait: (1) professional education materials; (2) fact sheets, pamphlets, and brochures; and (3) audiovisual material. A selected list of references is provided for the following topic areas: (1) genetic…

Anabolic agents: recent strategies for their detection and protection from inadvertent doping

PubMed Central

Geyer, Hans; Schänzer, Wilhelm; Thevis, Mario

2014-01-01

According to the World Anti-Doping Agency (WADA) Prohibited List, anabolic agents consist of exogenous anabolic androgenic steroids (AAS), endogenous AAS and other anabolic agents such as clenbuterol and selective androgen receptor modulators (SARMs). Currently employed strategies for their improved detection include the prolongation of the detection windows for exogenous AAS, non-targeted and indirect analytical approaches for the detection of modified steroids (designer steroids), the athlete’s biological passport and isotope ratio mass spectrometry for the detection of the misuse of endogenous AAS, as well as preventive doping research for the detection of SARMs. The recent use of these strategies led to 4–80-fold increases of adverse analytical findings for exogenous AAS, to the detection of the misuse of new designer steroids, to adverse analytical findings of different endogenous AAS and to the first adverse analytical findings of SARMs. The strategies of the antidoping research are not only focused on the development of methods to catch the cheating athlete but also to protect the clean athlete from inadvertent doping. Within the past few years several sources of inadvertent doping with anabolic agents have been identified. Among these are nutritional supplements adulterated with AAS, meat products contaminated with clenbuterol, mycotoxin (zearalenone) contamination leading to zeranol findings, and natural products containing endogenous AAS. The protection strategy consists of further investigations in case of reasonable suspicion of inadvertent doping, publication of the results, education of athletes and development of methods to differentiate between intentional and unintentional doping. PMID:24632537

40 CFR Appendix C to Subpart G of... - Substitutes Subject to Use Restrictions and Unacceptable Substitutes Listed in the May 22, 1996...

Code of Federal Regulations, 2013 CFR

2013-07-01

..., the statement “This refrigerant is FLAMMABLE. Take appropriate precautions.” b. This label must be... Narrowed Use Limits: Streaming Agents Application Substitute Decision Comments Halon 1211 CF3 I Acceptable in non-residential uses only Streaming Agents Aerosols—Proposed Acceptable Subject to Use Conditions...

Survival of the Human Granulocytic Ehrlichiosis Agent under Refrigeration Conditions

PubMed Central

Kalantarpour, Fatemeh; Chowdhury, Ishraq; Wormser, Gary P.; Aguero-Rosenfeld, Maria E.

2000-01-01

The human granulocytic ehrlichiosis (HGE) agent in infected blood specimens remained viable during refrigeration at 4°C for up to 18 days. These findings suggest that blood specimens submitted for culture may withstand transportation to a remote laboratory. HGE should be added to the list of infections potentially transmitted by blood transfusion. PMID:10835014

How to Change the Schools from Inside: Teachers As Change Agents.

ERIC Educational Resources Information Center

Nickse, Ruth S.

This paper presents the argument that teachers, with appropriate training, can be effective change agents within the school system. Among the reasons listed for teachers assuming leadership roles in change are the following: a) as professionals, they have a vested interest in the schooling process; b) since teachers are members of and identify…

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

PubMed Central

Martín-Dávila, P.; Fortún, J.; López-Vélez, R.; Norman, F.; Montes de Oca, M.; Zamarrón, P.; González, M. I.; Moreno, A.; Pumarola, T.; Garrido, G.; Candela, A.; Moreno, S.

2008-01-01

In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included. PMID:18202437

Molecular Imaging and Contrast Agent Database (MICAD): evolution and progress.

PubMed

Chopra, Arvind; Shan, Liang; Eckelman, W C; Leung, Kam; Latterner, Martin; Bryant, Stephen H; Menkens, Anne

2012-02-01

The purpose of writing this review is to showcase the Molecular Imaging and Contrast Agent Database (MICAD; www.micad.nlm.nih.gov ) to students, researchers, and clinical investigators interested in the different aspects of molecular imaging. This database provides freely accessible, current, online scientific information regarding molecular imaging (MI) probes and contrast agents (CA) used for positron emission tomography, single-photon emission computed tomography, magnetic resonance imaging, X-ray/computed tomography, optical imaging and ultrasound imaging. Detailed information on >1,000 agents in MICAD is provided in a chapter format and can be accessed through PubMed. Lists containing >4,250 unique MI probes and CAs published in peer-reviewed journals and agents approved by the United States Food and Drug Administration as well as a comma separated values file summarizing all chapters in the database can be downloaded from the MICAD homepage. Users can search for agents in MICAD on the basis of imaging modality, source of signal/contrast, agent or target category, pre-clinical or clinical studies, and text words. Chapters in MICAD describe the chemical characteristics (structures linked to PubChem), the in vitro and in vivo activities, and other relevant information regarding an imaging agent. All references in the chapters have links to PubMed. A Supplemental Information Section in each chapter is available to share unpublished information regarding an agent. A Guest Author Program is available to facilitate rapid expansion of the database. Members of the imaging community registered with MICAD periodically receive an e-mail announcement (eAnnouncement) that lists new chapters uploaded to the database. Users of MICAD are encouraged to provide feedback, comments, or suggestions for further improvement of the database by writing to the editors at micad@nlm.nih.gov.

Molecular Imaging and Contrast Agent Database (MICAD): Evolution and Progress

PubMed Central

Chopra, Arvind; Shan, Liang; Eckelman, W. C.; Leung, Kam; Latterner, Martin; Bryant, Stephen H.; Menkens, Anne

2011-01-01

The purpose of writing this review is to showcase the Molecular Imaging and Contrast Agent Database (MICAD; www.micad.nlm.nih.gov) to students, researchers and clinical investigators interested in the different aspects of molecular imaging. This database provides freely accessible, current, online scientific information regarding molecular imaging (MI) probes and contrast agents (CA) used for positron emission tomography, single-photon emission computed tomography, magnetic resonance imaging, x-ray/computed tomography, optical imaging and ultrasound imaging. Detailed information on >1000 agents in MICAD is provided in a chapter format and can be accessed through PubMed. Lists containing >4250 unique MI probes and CAs published in peer-reviewed journals and agents approved by the United States Food and Drug Administration (FDA) as well as a CSV file summarizing all chapters in the database can be downloaded from the MICAD homepage. Users can search for agents in MICAD on the basis of imaging modality, source of signal/contrast, agent or target category, preclinical or clinical studies, and text words. Chapters in MICAD describe the chemical characteristics (structures linked to PubChem), the in vitro and in vivo activities and other relevant information regarding an imaging agent. All references in the chapters have links to PubMed. A Supplemental Information Section in each chapter is available to share unpublished information regarding an agent. A Guest Author Program is available to facilitate rapid expansion of the database. Members of the imaging community registered with MICAD periodically receive an e-mail announcement (eAnnouncement) that lists new chapters uploaded to the database. Users of MICAD are encouraged to provide feedback, comments or suggestions for further improvement of the database by writing to the editors at: micad@nlm.nih.gov PMID:21989943

Brandon/Hill selected list of books and journals for the small medical library.

PubMed Central

Hill, D R

1999-01-01

The interrelationship of print and electronic media in the hospital library and its relevance to the "Brandon/Hill Selected List" in 1999 are addressed in the updated list (eighteenth version) of 627 books and 145 journals. This list is intended as a selection guide for the small or medium-size library in a hospital or similar facility. More realistically, it can function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Due to continuing requests from librarians, a "minimal core" book collection consisting of 82 titles has been pulled out from the 214 asterisked (*) initial-purchase books and marked with daggers ([symbol: see text]). To purchase the entire collection of books and to pay for 1999 journal subscriptions would require $114,900. The cost of only the asterisked items, books and journals, totals $49,100. The "minimal core" book collection costs $13,200. PMID:10219475

Optimising the selection of food items for FFQs using Mixed Integer Linear Programming.

PubMed

Gerdessen, Johanna C; Souverein, Olga W; van 't Veer, Pieter; de Vries, Jeanne Hm

2015-01-01

To support the selection of food items for FFQs in such a way that the amount of information on all relevant nutrients is maximised while the food list is as short as possible. Selection of the most informative food items to be included in FFQs was modelled as a Mixed Integer Linear Programming (MILP) model. The methodology was demonstrated for an FFQ with interest in energy, total protein, total fat, saturated fat, monounsaturated fat, polyunsaturated fat, total carbohydrates, mono- and disaccharides, dietary fibre and potassium. The food lists generated by the MILP model have good performance in terms of length, coverage and R 2 (explained variance) of all nutrients. MILP-generated food lists were 32-40 % shorter than a benchmark food list, whereas their quality in terms of R 2 was similar to that of the benchmark. The results suggest that the MILP model makes the selection process faster, more standardised and transparent, and is especially helpful in coping with multiple nutrients. The complexity of the method does not increase with increasing number of nutrients. The generated food lists appear either shorter or provide more information than a food list generated without the MILP model.

Circulation of core collection monographs in an academic medical library

PubMed Central

Schmidt, Cynthia M.; Eckerman, Nancy L.

2001-01-01

Academic medical librarians responsible for monograph acquisition face a challenging task. From the plethora of medical monographs published each year, academic medical librarians must select those most useful to their patrons. Unfortunately, none of the selection tools available to medical librarians are specifically intended to assist academic librarians with medical monograph selection. The few short core collection lists that are available are intended for use in the small hospital or internal medicine department library. As these are the only selection tools available, however, many academic medical librarians spend considerable time reviewing these collection lists and place heavy emphasis on the acquisition of listed books. The study reported here was initiated to determine whether the circulation of listed books in an academic library justified the emphasis placed on the acquisition of these books. Circulation statistics for “listed” and “nonlisted” books in the hematology (WH) section of Indiana University School of Medicine's Ruth Lilly Medical Library were studied. The average circulation figures for listed books were nearly two times as high as the corresponding figures for the WH books in general. These data support the policies of those academic medical libraries that place a high priority on collection of listed books. PMID:11337947

Biologics in pediatric psoriasis - efficacy and safety.

PubMed

Dogra, Sunil; Mahajan, Rahul

2018-01-01

Childhood psoriasis is a special situation that is a management challenge for the treating dermatologist. As is the situation with traditional systemic agents, which are commonly used in managing severe psoriasis in children, the biologics are being increasingly used in the recalcitrant disease despite limited data on long term safety. Areas covered: We performed an extensive literature search to collect evidence-based data on the use of biologics in pediatric psoriasis. The relevant literature published from 2000 to September 2017 was obtained from PubMed, using the MeSH words 'biologics', 'biologic response modifiers' and 'treatment of pediatric/childhood psoriasis'. All clinical trials, randomized double-blind or single-blind controlled trials, open-label studies, retrospective studies, reviews, case reports and letters concerning the use of biologics in pediatric psoriasis were screened. Articles covering the use of biologics in pediatric psoriasis were screened and reference lists in the selected articles were scrutinized to identify other relevant articles that had not been found in the initial search. Articles without relevant information about biologics in general (e.g. its mechanism of action, pharmacokinetics and adverse effects) and its use in psoriasis in particular were excluded. We screened 427 articles and finally selected 41 relevant articles. Expert opinion: The available literature on the use of biologics such as anti-tumor necrosis factor (TNF)-α agents, and anti-IL-12/23 agents like ustekinumab suggests that these are effective and safe in managing severe pediatric psoriasis although there is an urgent need to generate more safety data. Dermatologists must be careful about the potential adverse effects of the biologics before administering them to children with psoriasis. It is likely that with rapidly evolving scenario of biologics in psoriasis, these will prove to be very useful molecules particularly in managing severe and recalcitrant psoriasis in pediatric age group.

Evaluation of Persistence of Viruses in Landfill Leachate ...

EPA Pesticide Factsheets

Report The purpose of this effort was to assess the persistence of viruses in landfill leachate. To determine whether active viruses could pose a threat to human and environmental health once introduced into a landfill, laboratory testing was performed to measure the decay rate of viral agents in landfill leachate. This effort was performed using surrogate test agents similar to BW agents following the well-established hypothesis that, though the diversity of viral contaminants may be quite large, a limited list of viral surrogates can be chosen that qualitatively represent the likely BW threat agents of interest.

Preventable Exposures Associated With Human Cancers

PubMed Central

Baan, Robert; Straif, Kurt; Grosse, Yann; Lauby-Secretan, Béatrice; El Ghissassi, Fatiha; Bouvard, Véronique; Benbrahim-Tallaa, Lamia; Guha, Neela; Freeman, Crystal; Galichet, Laurent; Wild, Christopher P.

2011-01-01

Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International Agency for Research on Cancer (IARC) Monograph series, which has classified human carcinogens for more than 40 years, recently completed a review to provide up-to-date information on the cancer sites associated with more than 100 carcinogenic agents. Based on IARC’s review, we listed the cancer sites associated with each agent and then rearranged this information to list the known and suspected causes of cancer at each site. We also summarized the rationale for classifications that were based on mechanistic data. This information, based on the forthcoming IARC Monographs Volume 100, offers insights into the current state-of-the-science of carcinogen identification. Use of mechanistic data to identify carcinogens is increasing, and epidemiological research is identifying additional carcinogens and cancer sites or confirming carcinogenic potential under conditions of lower exposure. Nevertheless, some common human cancers still have few (or no) identified causal agents. PMID:22158127

The long-term value of the selected list as a method of controlling drug costs in a district general hospital.

PubMed

Upton, D R; Holmes, G K; Fox, P D; Cullen, A M; Poston, J W

1989-02-01

The results of a study aimed at evaluating the long-term effects of the Limited List (now officially referred to as the Selected List Scheme) on inpatient drug costs in a district general hospital (DGH) are presented. Study periods of six months duration were examined before, shortly after, and a further year after implementation of the List on 1 April 1985. Eight therapeutic classes affected by the regulations were examined; in four of these (antacids, expectorants, mucolytics and anxiolytics, hypnotics and sedatives) statistically significant reductions in costs were demonstrated over the study periods. There was no significant change in the costs of the other four classes (vitamins, laxatives, nasal preparations and analgesics). Overall, inpatient expenditure for the hospital showed no significant change. The changes in cost demonstrated can be attributed to the Selected List and occurred despite the prior existence of a local formulary.

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N

1971-04-01

This updated list of 389 books and 135 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk.

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N

1969-04-01

This updated list of 398 books and 141 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk.

76 FR 29754 - Proposed Data Collections Submitted for Public Comment and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-23

... Agent or Toxin, (3) Report of Theft, Loss, or Release of Select Agent and Toxin, (4) Report of..., Use, and Transfer of Select Agents and Toxins (OMB Control No. 0920-0576)--Revision--Office of Public Health Preparedness and Response (OPHPR), Division of Select Agents and Toxins, Centers for Disease...

Emergence of social structures via preferential selection

NASA Astrophysics Data System (ADS)

Lipowski, Adam; Lipowska, Dorota; Ferreira, Antonio Luis

2014-09-01

We examine a weighted-network multiagent model with preferential selection such that agents choose partners with probability p (w), where w is the number of their past selections. When p (w) increases sublinearly with the number of past selections [p(w)˜wα,α<1], agents develop a uniform preference for all other agents. At α =1, this state loses stability and more complex structures form. For a superlinear increase (α>1), strong heterogeneities emerge and agents make selections mainly within small and sometimes asymmetric clusters. Even in a few-agent case, the formation of such clusters resembles phase transitions with spontaneous symmetry breaking.

Animal Rights: Selected Resources and Suggestions for Further Study.

ERIC Educational Resources Information Center

Davidoff, Donald J.

1989-01-01

Presents an annotated list of selected resources intended to serve as a guide to the growing amount of material on animal rights. Suggestions to aid in additional research include subject headings used to find books, indexes used to locate periodical articles, sources for locating organizations, and a selected list of animal rights organizations.…

40 CFR Appendix L to Subpart G of... - Substitutes Listed in the January 27, 2003, Final Rule, Effective March 28, 2003

Code of Federal Regulations, 2014 CFR

2014-07-01

... environments protected by HFC227-BC extinguishing systemsEach HFC227-BC extinguisher should be clearly labelled... Agent Fire Extinguishing Systems. See additional comments 1, 2, 3, 4, 5. Additional comments. 1—Should... or performance requirements. 4—The agent should be recovered from the fire protection system in...

40 CFR Appendix P to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2012 CFR

2012-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... requirements. 4—The agent should be recovered from the fire protection system in conjunction with testing or... coverage related to the use of personal protective equipment (e.g., respiratory protection), fire...

40 CFR Appendix P to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2013 CFR

2013-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... requirements. 4—The agent should be recovered from the fire protection system in conjunction with testing or... coverage related to the use of personal protective equipment (e.g., respiratory protection), fire...

40 CFR Appendix L to Subpart G of... - Substitutes Listed in the January 27, 2003, Final Rule, Effective March 28, 2003

Code of Federal Regulations, 2013 CFR

2013-07-01

... environments protected by HFC227-BC extinguishing systemsEach HFC227-BC extinguisher should be clearly labelled... Agent Fire Extinguishing Systems. See additional comments 1, 2, 3, 4, 5. Additional comments. 1—Should... or performance requirements. 4—The agent should be recovered from the fire protection system in...

40 CFR Appendix L to Subpart G of... - Substitutes Listed in the January 27, 2003, Final Rule, Effective March 28, 2003

Code of Federal Regulations, 2012 CFR

2012-07-01

... environments protected by HFC227-BC extinguishing systemsEach HFC227-BC extinguisher should be clearly labelled... Agent Fire Extinguishing Systems. See additional comments 1, 2, 3, 4, 5. Additional comments. 1—Should... or performance requirements. 4—The agent should be recovered from the fire protection system in...

40 CFR Appendix P to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2014 CFR

2014-07-01

... latest edition of the NFPA 2001 Standard for Clean Agent Fire Extinguishing Systems, for whichever... requirements. 4—The agent should be recovered from the fire protection system in conjunction with testing or... coverage related to the use of personal protective equipment (e.g., respiratory protection), fire...

40 CFR Appendix O to Subpart G of... - Substitutes Listed in the September 27, 2006 Final Rule, Effective November 27, 2006

Code of Federal Regulations, 2010 CFR

2010-07-01

... End-use Substitute Decision Conditions Further information Total flooding Gelled Halocarbon/Dry... ventilation should be in place to reduce airborne exposure to constituents of agent; —An eye wash fountain and... reduce airborne exposure to constituents of agent; —An eye wash fountain and quick drench facility should...

75 FR 54496 - Diseases Associated With Exposure to Certain Herbicide Agents (Hairy Cell Leukemia and Other...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... Certain Herbicide Agents (Hairy Cell Leukemia and Other Chronic B-Cell Leukemias, Parkinson's Disease and..., VA published in the Federal Register (75 FR 53202), an amendment to 38 CFR 3.309 to add hairy cell leukemia and other chronic B-cell leukemias, Parkinson's disease and ischemic heart disease to the list of...

75 FR 76940 - User Fees Relating to Enrolled Agents and Enrolled Retirement Plan Agents

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

... Friday between the hours of 8 a.m. and 4 p.m. to CC:PA:LPD:PR (REG- 124018-10), Courier's Desk, Internal..., DC. FOR FURTHER INFORMATION CONTACT: Concerning the proposed regulations, Emily M. Lesniak at (202... comments, the public hearing, or to be placed on the building access list to attend the public hearing...

42 CFR 73.3 - HHS select agents and toxins.

Code of Federal Regulations, 2010 CFR

2010-10-01

... been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria are... Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the select agent viruses...

NASA Parts Selection List (NPSL) WWW Site http://nepp.nasa.gov/npsl

NASA Technical Reports Server (NTRS)

Brusse, Jay

2000-01-01

The NASA Parts Selection List (NPSL) is an on-line resource for electronic parts selection tailored for use by spaceflight projects. The NPSL provides a list of commonly used electronic parts that have a history of satisfactory use in spaceflight applications. The objective of this www site is to provide NASA projects, contractors, university experimenters, et al with an easy to use resource that provides a baseline of electronic parts from which designers are encouraged to select. The NPSL is an ongoing resource produced by Code 562 in support of the NASA HQ funded NASA Electronic Parts and Packaging (NEPP) Program. The NPSL is produced as an electronic format deliverable made available via the referenced www site administered by Code 562. The NPSL does not provide information pertaining to patented or proprietary information. All of the information contained in the NPSL is available through various other public domain resources such as US Military procurement specifications for electronic parts, NASA GSFC's Preferred Parts List (PPL-21), and NASA's Standard Parts List (MIL-STD975).

Antimicrobial activity of chemomechanical gingival retraction products.

PubMed

Hsu, Belinda; Lee, Stephanie; Schwass, Donald; Tompkins, Geoffrey

2017-07-01

Application of astringent hemostatic agents is the most widely used technique for gingival retraction, and a variety of products are offered commercially. However, these products may have additional unintended yet clinically beneficial properties. The authors assessed the antimicrobial activities of marketed retraction products against plaque-associated bacteria in both planktonic and biofilm assays, in vitro. The authors assessed hemostatic solutions, gels, pellets, retraction cords, pastes, and their listed active agents against a collection of microorganisms by means of conventional agar diffusion and minimum bacteriostatic and bactericidal concentration determinations. The authors then tested the most active products against monospecies biofilms grown on hydroxyapatite disks. All of the tested retraction products exhibited some antimicrobial activity. The results of the most active products were comparable with those of a marketed mouthwash. The listed retraction-active agents displayed relatively little activity when tested in pure form. At 10% dilution, some products evidenced inhibitory activity against most tested bacteria within 3 minutes of exposure, whereas others displayed variable effects after 10 minutes. The most active agents reduced, but did not completely prevent, the metabolic activity of a monospecies biofilm. Commercial gingival retraction products exhibit antimicrobial effects to various degrees in vitro. Some products display rapid bactericidal activity. The antimicrobial activity is not owing to the retraction-active agents. Biofilm bacteria are less sensitive to the antimicrobial effects of the agents. The rapidity of killing by some hemostatic agents suggests an antimicrobial effect that may be efficacious during clinical placement. The results of this in vitro study suggest that clinicians should be aware of the potential antimicrobial effects of some hemostatic agents, but more research is needed to confirm these observations in clinical use. Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.

Selective Attention and Control of Action: Comparative Psychology of an Artificial, Evolved Agent and People

ERIC Educational Resources Information Center

Ward, Robert; Ward, Ronnie

2008-01-01

This study examined the selective attention abilities of a simple, artificial, evolved agent and considered implications of the agent's performance for theories of selective attention and action. The agent processed two targets in continuous time, catching one and then the other. This task required many cognitive operations, including prioritizing…

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1997-01-01

The introduction to this revised list (seventeenth version) of 610 books and 141 journals addresses the origin, three decades ago, of the "Selected List of Books and Journals for the Small Medical Library," and the accomplishments of the late Alfred N. Brandon in helping health sciences librarians, and especially hospital librarians, to envision what collection development and a library collection are all about. This list is intended as a selection guide for the small or medium-size library in a hospital or similar facility. More realistically, it can function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Due to continuing requests from librarians, a "minimal core" book collection consisting of 78 titles has been pulled out from the 200 asterisked (*) initial-purchase books and marked with daggers ([symbol: see text]). To purchase the entire collection of books and to pay for 1997 journal subscriptions would require $101,700. The cost of only the asterisked items, books and journals, totals $43,100. The "minimal core" book collection costs $12,600. PMID:9160148

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N; Hill, D R

1997-04-01

The introduction to this revised list (seventeenth version) of 610 books and 141 journals addresses the origin, three decades ago, of the "Selected List of Books and Journals for the Small Medical Library," and the accomplishments of the late Alfred N. Brandon in helping health sciences librarians, and especially hospital librarians, to envision what collection development and a library collection are all about. This list is intended as a selection guide for the small or medium-size library in a hospital or similar facility. More realistically, it can function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Due to continuing requests from librarians, a "minimal core" book collection consisting of 78 titles has been pulled out from the 200 asterisked (*) initial-purchase books and marked with daggers ([symbol: see text]). To purchase the entire collection of books and to pay for 1997 journal subscriptions would require $101,700. The cost of only the asterisked items, books and journals, totals $43,100. The "minimal core" book collection costs $12,600.

40 CFR Appendix Vi to Part 261 - Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary Materials Wording of the instruments. Appendix VI to Part 261 [Reserved for Etiologic Agents] ...

Selected List of Books and Journals for the Small Medical Library *

PubMed Central

Brandon, Alfred N.

1969-01-01

This updated list of 398 books and 141 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk. PMID:4888285

Selected List of Books and Journals for the Small Medical Library *

PubMed Central

Brandon, Alfred N.

1971-01-01

This updated list of 389 books and 135 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk. PMID:5582092

Business Education Index 1995. Index of Business Education Articles and Research Studies Compiled from a Selected List of Periodicals Published during the Year 1995.

ERIC Educational Resources Information Center

Noll, Cheryl L., Ed.; And Others

This index lists more than 2,000 business education articles and research studies that were published during 1995 in a selected list of periodicals that have been deemed essential to research and teaching in the broad business education spectrum. Among the subject categories under which articles are indexed are the following: administration and…

Business Education Index 1987. Volume 48. Index of Business Education Articles, Research Studies, and Textbooks Compiled from a Selected List of Periodicals, Publishers, and Yearbooks Published during the Year 1987.

ERIC Educational Resources Information Center

McCauley, Rosemarie, Ed.

1988-01-01

This index lists business education articles, research studies, and textbooks that were compiled from a selected list of periodicals, publishers, and yearbooks published during 1987. A total of 19 general publications and 48 periodicals were indexed. The materials are indexed under 94 subject headings, including the following: accounting,…

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N; Hill, D R

1981-04-01

This revised list of 539 books and 136 journals is intended as a selection guide for small or medium-sized hospital libraries or for small medical libraries in comparable health care facilities. It can also be used as a core list by consortia of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author index and the list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries, 137 books and 54 journals, are indicated by asterisks. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $30,000. The cost of only the asterisked items, which are recommended for first purchase, totals approximately $8,900.

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1989-01-01

In the introduction to this revised list of 607 books and 141 journals, quality assurance programs of health care institutions and patient education are suggested as vehicles for more directly involving the hospital library and its collection in patient care. This list is intended as a selection guide for the small or medium-sized library in a hospital or comparable medical facility, or as a core collection for a consortium of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. To purchase the entire collection of books and to pay for 1989 subscriptions would require about $63,500. The cost of only the asterisked items totals $24,000. PMID:2655782

Brandon/Hill selected list of print books and journals for the small medical library*

PubMed Central

Hill, Dorothy R.; Stickell, Henry N.

2001-01-01

After thirty-six years of biennial updates, the authors take great pride in being able to publish the nineteenth version (2001) of the “Brandon/Hill Selected List of Print Books and Journals for the Small Medical Library.” This list of 630 books and 143 journals is intended as a selection guide for health sciences libraries or similar facilities. It can also function as a core collection for a library consortium. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals, by an alphabetical title listing. Due to continuing requests from librarians, a “minimal core list” consisting of 81 titles has been pulled out from the 217 asterisked (*) initial-purchase books and marked with daggers (†*) before the asterisks. To purchase the entire collection of 630 books and to pay for 143 2001 journal subscriptions would require $124,000. The cost of only the asterisked items, books and journals, totals $55,000. The “minimal core list” book collection costs approximately $14,300. PMID:11337945

Interleukin-21: updated review of Phase I and II clinical trials in metastatic renal cell carcinoma, metastatic melanoma and relapsed/refractory indolent non-Hodgkin's lymphoma.

PubMed

Hashmi, Mehmood H; Van Veldhuizen, Peter J

2010-05-01

In advanced renal cell cancer and malignant melanoma, the current FDA approved immune modulators, such as IL-2, are the only agents which provide a durable complete remission. These responses, however, occur in < 10% of treated patients and their applicability is limited to selected patients because of their toxicity. The identification of new immunotherapeutic agents with an improved response rate and toxicity profile would represent a significant advancement in the treatment of these malignancies. This is a comprehensive review of IL-21 including its pharmacology and current developmental status. A literature review was performed using all PubMed listed publications involving IL-21, including original research articles, reviews and abstracts. It also includes a review of current ongoing trials and information from the official product website. Recombinant IL-21 (rIL-21) is a new immune modulator currently undergoing Phase I and II testing. It is a cytokine with a four helix structure that has structural and sequence homology to IL-2 and -15, but also possesses many unique biological properties. In this review, we evaluate the development, pharmacologic properties, safety profile and current clinical efficacy of rIL-21. rIL-21 has an acceptable safety profile and encouraging single agent activity in early phase renal cell carcinoma and melanoma clinical trials.

Behavioral Studies in Communication, A Selected Bibliography, 1973.

ERIC Educational Resources Information Center

Steinfatt, Thomas M.

The studies in communication behavior listed in this selected bibliography were published during 1973, unless otherwise specified. Entries are listed under 12 categories: cross cultural communication; diffusion; games, simulations, and conflict; general communication variables; group and organizational communication; interpersonal communication;…

Advanced On-The-Job Training System: User’s Handbook (Sections 10-11). Volume 3

DTIC Science & Technology

1990-05-01

leWd 4. idsodity a ne bety position Quit This Plan Select Option: Z (i)d4L.-tti irman Ifrom List, ()nter Specific S, (q)uit ? I 10-2.-4 0 The AOTS...Print SUperviaima List q. Rit This Plans Select Option: S 10-44 STEP 6: SELECT THE SUPERVISION LIST OPTION. Enter 5 and press 3RETU 30 D RA FT AOTS...training is accomplished by the trainee completing an on-line CAI lesson , while for other tasks, knowledge training is accomplished off line by the trainee

Selective attention and control of action: comparative psychology of an artificial, evolved agent and people.

PubMed

Ward, Robert; Ward, Ronnie

2008-10-01

This study examined the selective attention abilities of a simple, artificial, evolved agent and considered implications of the agent's performance for theories of selective attention and action. The agent processed two targets in continuous time, catching one and then the other. This task required many cognitive operations, including prioritizing the first target (T1) over the second (T2); selectively focusing responses on T1, while preventing T2 from interfering with responses; creating a memory for the unselected T2 item, so that it could be efficiently processed later; and reallocating processing towards T2 after catching T1. The evolved agent demonstrated all these abilities. Analysis shows that the agent used reactive inhibition to selectively focus behavior. That is, the more salient T2, the more strongly responses towards T2 were inhibited and the slower the agent was to subsequently reallocate processing towards T2. Reactive inhibition was also suggested in two experiments with people, performing a virtually identical catch task. The presence of reactive inhibition in the simple agent and in people suggests that it is an important mechanism for selective processing.

Multi-agent Reinforcement Learning Model for Effective Action Selection

NASA Astrophysics Data System (ADS)

Youk, Sang Jo; Lee, Bong Keun

Reinforcement learning is a sub area of machine learning concerned with how an agent ought to take actions in an environment so as to maximize some notion of long-term reward. In the case of multi-agent, especially, which state space and action space gets very enormous in compared to single agent, so it needs to take most effective measure available select the action strategy for effective reinforcement learning. This paper proposes a multi-agent reinforcement learning model based on fuzzy inference system in order to improve learning collect speed and select an effective action in multi-agent. This paper verifies an effective action select strategy through evaluation tests based on Robocop Keep away which is one of useful test-beds for multi-agent. Our proposed model can apply to evaluate efficiency of the various intelligent multi-agents and also can apply to strategy and tactics of robot soccer system.

Deceptive Tactics for Protecting Cities Against Vehicle Borne Improvised Explosive Devices

DTIC Science & Technology

2008-03-01

burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instruction, searching...INTENTIONALLY LEFT BLANK xiii LIST OF ABBREVIATIONS ABS Agent Based Simulation ANA Agent Network Attack DVF Detection Value Function GIS Geographic...any other behavior (than perceptive) may be advantageous to the attacker. - A communicative behavior proves particularly effective over time for the

17 CFR 249.1330 - Form MA-NR, for appointment of agent for service of process by non-resident municipal advisor...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Form MA-NR, for appointment of... Information Regarding Certain Natural Persons § 249.1330 Form MA-NR, for appointment of agent for service of... Register citations affecting Form MA-NR, see the List of CFR Sections Affected, which appears in the...

77 FR 28640 - Product List Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-15

... POSTAL REGULATORY COMMISSION [Docket Nos. MC2012-15 and CP2012-22; Order No. 1334] Product List... competitive product list. This notice addresses procedural steps associated with this filing. DATES: Comments... the competitive product list.\\1\\ The Postal Service asserts that Parcel Select and Parcel Return...

FDA Expands List of "Do Not Compound" Drug Products.

PubMed

2017-03-01

EDITOR'S ABSTRACT On October 3, 2016, the U.S. Food and Drug Administration published in the Federal Register an expanded list of drug products that are not to be used in compounding extemporaneous dosage forms. This list contains numerous analgesic or anti-inflammatory agents and other chemicals sometimes used to manage pain and related symptoms. Because pharmacies are licensed by the states and other jurisdictions (districts, territories) as opposed to the federal government, regulation of extemporaneous compounding is inconsistent across the nation and minimal to nonexistent is some jurisdictions. Clinicians are urged to assure that pharmacies they and their patients use adhere to this list and compound only dosage forms for which there is good evidence of both safety and efficacy.

Tales of the Supernatural: A Selected List of Recordings Made in the United States and Placed in the Archive of Folk Culture. Folk Archive Finding Aid.

ERIC Educational Resources Information Center

Delcambre, Angie C., Comp.; And Others

This finding aid is a selected list of supernatural-related narratives recorded in the United States and held in the Archive of Folk Culture of the Library of Congress. Brief descriptions of the recordings are accompanied by identification numbers. Information about listening to or ordering any of the listed recordings is available from the…

A Rock Retrospective.

ERIC Educational Resources Information Center

O'Grady, Terence J.

1979-01-01

The author offers an analysis of musical techniques found in the major rock trends of the 1960s. An annotated list of selected readings and a subject-indexed list of selected recordings are appended. This article is part of a theme issue on popular music. (Editor/SJL)

Selected Reference Books of 1971-72

ERIC Educational Resources Information Center

Sheehy, Eugene P.

1973-01-01

The purpose of this annotated list is to present a selection of recent scholarly and foreign works of interest to reference workers in university libraries. The citations are listed under the following headings: guide, bibliography, encyclopedias, dictionaries, newspapers, dissertations, biography, genealogy, literature, education, sociology,…

SELECTED INSTRUCTIONAL MATERIALS FOR DISTRIBUTIVE EDUCATION.

ERIC Educational Resources Information Center

LEVENDOWSKI, J.C.

CITATIONS SUPPLEMENTING BULLETIN NO. 5, "DISTRIBUTIVE EDUCATION LIBRARY LIST," (ED 012 778) WERE SELECTED FOR DISTRIBUTIVE TEACHER EDUCATORS, ADULT INSTRUCTORS AND TEACHER COORDINATORS. THE PUBLICATIONS ARE FREE OR INEXPENSIVE BROCHURES, BULLETINS, PAMPHLETS AND PAPERBACK BOOKS, LISTED BY TOPICS--(1) "ADVERTISING AND DISPLAY," (2) "DISTRIBUTIVE…

THE SELECTION OF A NATIONAL RANDOM SAMPLE OF TEACHERS FOR EXPERIMENTAL CURRICULUM EVALUATION.

ERIC Educational Resources Information Center

WELCH, WAYNE W.; AND OTHERS

MEMBERS OF THE EVALUATION SECTION OF HARVARD PROJECT PHYSICS, DESCRIBING WHAT IS SAID TO BE THE FIRST ATTEMPT TO SELECT A NATIONAL RANDOM SAMPLE OF (HIGH SCHOOL PHYSICS) TEACHERS, LIST THE STEPS AS (1) PURCHASE OF A LIST OF PHYSICS TEACHERS FROM THE NATIONAL SCIENCE TEACHERS ASSOCIATION (MOST COMPLETE AVAILABLE), (2) SELECTION OF 136 NAMES BY A…

TVDG LET Calculator

Science.gov Websites

Sodium Iodide Water Select your Ion from the list 1 Hydrogen 1 2 Helium 4 3 Lithium 7 4 Beryllium 9 5 . It works reasonably well for ion energies larger than ~1 MeV/amu and for ions heavier than lithium the Specified Ion in the Specified Target. Select the Target Material from the dropdown list. Select

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1981-01-01

This revised list of 539 books and 136 journals is intended as a selection guide for small or medium-sized hospital libraries or for small medical libraries in comparable health care facilities. It can also be used as a core list by consortia of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author index and the list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries, 137 books and 54 journals, are indicated by asterisks. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $30,000. The cost of only the asterisked items, which are recommended for first purchase, totals approximately $8,900. PMID:7225656

Thin film composition with biological substance and method of making

DOEpatents

Campbell, Allison A.; Song, Lin

1999-01-01

The invention provides a thin-film composition comprising an underlying substrate of a first material including a plurality of attachment sites; a plurality of functional groups chemically attached to the attachment sites of the underlying substrate; and a thin film of a second material deposited onto the attachment sites of the underlying substrate, and a biologically active substance deposited with the thin-film. Preferably the functional groups are attached to a self assembling monolayer attached to the underlying substrate. Preferred functional groups attached to the underlying substrate are chosen from the group consisting of carboxylates, sulfonates, phosphates, optionally substituted, linear or cyclo, alkyl, alkene, alkyne, aryl, alkylaryl, amine, hydroxyl, thiol, silyl, phosphoryl, cyano, metallocenyl, carbonyl, and polyphosphate. Preferred materials for the underlying substrate are selected from the group consisting of a metal, a metal alloy, a plastic, a polymer, a proteic film, a membrane, a glass or a ceramic. The second material is selected from the group consisting of inorganic crystalline structures, inorganic amorphus structures, organic crystalline structures, and organic amorphus structures. Preferred second materials are phosphates, especially calcium phosphates and most particularly calcium apatite. The biologically active molecule is a protein, peptide, DNA segment, RNA segment, nucleotide, polynucleotide, nucleoside, antibiotic, antimicrobal, radioisotope, chelated radioisotope, chelated metal, metal salt, anti-inflamatory, steriod, nonsteriod anti-inflammatory, analgesic, antihistamine, receptor binding agent, or chemotherapeutic agent, or other biologically active material. Preferably the biologically active molecule is an osteogenic factor the compositions listed above.

Wyoming Basin Rapid Ecoregional Assessment: Work Plan

USGS Publications Warehouse

Carr, Natasha B.; Garman, Steven L.; Walters, Annika; Ray, Andrea; Melcher, Cynthia P.; Wesner, Jeff S.; O’Donnell, Michael S.; Sherrill, Kirk R.; Babel, Nils C.; Bowen, Zachary H.

2013-01-01

The overall goal of the Rapid Ecoregional Assessments (REAs) being conducted for the Bureau of Land Management (BLM) is to provide information that supports regional planning and analysis for the management of ecological resources. The REA provides an assessment of baseline ecological conditions, an evaluation of current risks from drivers of ecosystem change, and a predictive capacity for evaluating future risks. The REA also may be used for identifying priority areas for conservation or restoration and for assessing the cumulative effects of a variety of land uses. There are several components of the REAs. Management Questions, developed by the BLM and partners for the ecoregion, identify the information needed for addressing land-management responsibilities. Conservation Elements represent regionally significant aquatic and terrestrial species and communities that are to be conserved and (or) restored. The REA also will evaluate major drivers of ecosystem change (Change Agents) currently affecting or likely to affect the status of Conservation Elements. We selected 8 major biomes and 19 species or species assemblages to be included as Conservation Elements. We will address the four primary Change Agents—development, fire, invasive species, and climate change—required for the REA. The purpose of the work plan for the Wyoming Basin REA is to document the selection process for, and final list of, Management Questions, Conservation Elements, and Change Agents. The work plan also presents the overall assessment framework that will be used to assess the status of Conservation Elements and answer Management Questions.

SIMPLE GREEN® (Dual listing for 2013 reformulation)

EPA Pesticide Factsheets

Technical product bulletin: this surface washing agent is suitable for use in oil spill cleanups in freshwater, estuarine, and marine environments at all temperatures, on both porous and non-porous surfaces.

Insect mycophagy: a preliminary bibliography.

Treesearch

Robert. Fogel

1975-01-01

Insects that feed on fungi are primary dispersal agents for many beneficial and pathogenic species. Nearly 300 references on the subject, published since the mid-19th century are listed in this bibliography.

21 CFR 176.200 - Defoaming agents used in coatings.

Code of Federal Regulations, 2014 CFR

2014-04-01

... are provided: List of substances Limitations n-Butyl alcohol tert-Butyl alcohol Butyl stearate Castor... Glyceryl monostearate Hexane Hexylene glycol (2-methyl-2,4-pentanediol) Isobutyl alcohol Isopropyl alcohol...

Information networks in the stock market based on the distance of the multi-attribute dimensions between listed companies

NASA Astrophysics Data System (ADS)

Liu, Qian; Li, Huajiao; Liu, Xueyong; Jiang, Meihui

2018-04-01

In the stock market, there are widespread information connections between economic agents. Listed companies can obtain mutual information about investment decisions from common shareholders, and the extent of sharing information often determines the relationships between listed companies. Because different shareholder compositions and investment shares lead to different formations of the company's governance mechanisms, we map the investment relationships between shareholders to the multi-attribute dimensional spaces of the listed companies (each shareholder investment in a company is a company dimension). Then, we construct the listed company's information network based on co-shareholder relationships. The weights for the edges in the information network are measured with the Euclidean distance between the listed companies in the multi-attribute dimension space. We define two indices to analyze the information network's features. We conduct an empirical study that analyzes Chinese listed companies' information networks. The results from the analysis show that with the diversification and decentralization of shareholder investments, almost all Chinese listed companies exchanged information through common shareholder relationships, and there is a gradual reduction in information sharing capacity between listed companies that have common shareholders. This network analysis has benefits for risk management and portfolio investments.

Selected Resources on Suicide: Causes and Prevention.

ERIC Educational Resources Information Center

Crase, Darrell

This selected bibliography lists many of the contemporary resources on suicide and its varied dimensions representing the health sciences, social sciences, and medicine. The materials include books, periodical literature, dissertations, audiovisuals, journals, and a list of related professional organizations. In addition to a general discussion of…

Summertime Favorites.

ERIC Educational Resources Information Center

National Endowment for the Humanities (NFAH), Washington, DC.

Compiled from the reading lists of 60 exemplary schools, this "summertime" reading list provides titles of tried-and-true works published in or before 1960 which appeared on at least five of the school reading lists. Selections are divided according to grade level. The list offers over 100 book or series of titles recommended for…

Proyecto Leer Bulletin, Number 8.

ERIC Educational Resources Information Center

Benson, Susan Shattuck

This bulletin lists educational materials for the Spanish speaking. Several hundred documents are listed in three main sections: (1) organizations, programs, laws, and news related to the Spanish speaking; (2) a list of books selected; and (3) a list of publishers and distributors with their addresses. Several bibliographies are included. Entries…

Evaluating candidate reactions to selection practices using organisational justice theory.

PubMed

Patterson, Fiona; Zibarras, Lara; Carr, Victoria; Irish, Bill; Gregory, Simon

2011-03-01

This study aimed to examine candidate reactions to selection practices in postgraduate medical training using organisational justice theory. We carried out three independent cross-sectional studies using samples from three consecutive annual recruitment rounds. Data were gathered from candidates applying for entry into UK general practice (GP) training during 2007, 2008 and 2009. Participants completed an evaluation questionnaire immediately after the short-listing stage and after the selection centre (interview) stage. Participants were doctors applying for GP training in the UK. Main outcome measures were participants' evaluations of the selection methods and perceptions of the overall fairness of each selection stage (short-listing and selection centre). A total of 23,855 evaluation questionnaires were completed (6893 in 2007, 10,497 in 2008 and 6465 in 2009). Absolute levels of perceptions of fairness of all the selection methods at both the short-listing and selection centre stages were consistently high over the 3years. Similarly, all selection methods were considered to be job-related by candidates. However, in general, candidates considered the selection centre stage to be significantly fairer than the short-listing stage. Of all the selection methods, the simulated patient consultation completed at the selection centre stage was rated as the most job-relevant. This is the first study to use a model of organisational justice theory to evaluate candidate reactions during selection into postgraduate specialty training. The high-fidelity selection methods are consistently viewed as more job-relevant and fairer by candidates. This has important implications for the design of recruitment systems for all specialties and, potentially, for medical school admissions. Using this approach, recruiters can systematically compare perceptions of the fairness and job relevance of various selection methods. © Blackwell Publishing Ltd 2011.

Information Seeking Behavior and User Education in Academic Libraries: Research, Theory, and Practice. A Selected List of Information Sources.

ERIC Educational Resources Information Center

Fridie, Stephanie, Comp.

This document lists sources useful for academic reference and instruction librarians who are concerned with assisting and teaching novice or non-professional end-user searchers. The bibliography is organized in two lists: complete bibliographic citations and subject listing of references. The types of sources listed include journal articles,…

The Real-Time ObjectAgent Software Architecture for Distributed Satellite Systems

DTIC Science & Technology

2001-01-01

real - time operating system selection are also discussed. The fourth section describes a simple demonstration of real-time ObjectAgent. Finally, the...experience with C++. After selecting the programming language, it was necessary to select a target real - time operating system (RTOS) and embedded...ObjectAgent software to run on the OSE Real Time Operating System . In addition, she is responsible for the integration of ObjectAgent

Dioxins and dioxin-like chemicals in blood and semen of American Vietnam veterans from the state of Michigan.

PubMed

Schecter, A; McGee, H; Stanley, J S; Boggess, K; Brandt-Rauf, P

1996-12-01

This exposure assessment pilot study tested the hypothesis that elevated blood levels of the dioxin congener 2,3,7,8-TCDD ("TCDD"), due to Agent Orange exposure, in American Vietnam veterans could be demonstrated two to three decades after Vietnam service. A second objective was to determine if dioxins, including TCDD, are present in the semen of adult males. In the early 1990s, blood samples from 50 Vietnam veterans and three pooled semen samples from 17 of them were analyzed by high-resolution gas chromatography-mass spectroscopy for dioxins, dibenzofurans, and the dioxin-like PCBs. Fifty volunteers from the Michigan Vietnam veteran bonus list, which documented Vietnam service, were invited to participate based on their self-reported exposure to Agent Orange in Vietnam. Screening of military and medical records was performed by an epidemiologist and a physician to assure that Agent Orange exposure was possible based on job description, location of service in Vietnam, and military Agent Orange spray records. Elevated 2,3,7,8-TCDD levels, over 20 ppt on a lipid basis, could still be detected in six of the 50 veterans in this nonrandomly selected group. The dioxin and dibenzofuran congeners commonly found in the U.S. population, including TCDD, were also detected in the three pooled semen samples. Quantification and comparison on a lipid basis were not possible due to low lipid concentrations where levels were below the detection limit. Therefore, semen samples were measured and reported on a wet-weight basis. Elevated blood TCDD levels, probably related to Agent Orange exposure, can be detected between two and three decades after potential exposure in some American veterans. Original levels were estimated to be 35-1,500-fold greater that that of the general population (4 ppt, lipid) at the time of exposure. In addition, the detection of dioxins in semen suggests a possible mechanism for male-mediated adverse reproductive outcomes following Agent Orange or other dioxin exposure.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The bibliography contains citations concerning the use of biological agents to control insects and pests. Radiation, genetic breeding, bacteria, fungi, viruses, and pheromones are discussed as alternatives to pesticidal management. Methods for monitoring the effectiveness and environmental impact of these agents are reviewed. Population control of fruit flies, spruce sawflies, flies, mosquitoes, cockroaches, gypsy moths, and other agriculturally-important insects is also discussed. (Contains a minimum of 190 citations and includes a subject term index and title list.)

Small-Item Contact Test Method, FY11 Release

DTIC Science & Technology

2012-07-01

the exposure mass of the agent. APPENDIX 8 Comparison of data using different contact swabs should include consideration for the material- uptake ...Terminology specific to this test procedure is provided alphabetically in the following list. • absorption: The uptake of a contaminant INTO the...substance with the ability to remove and/or neutralize chemical agents on/in surfaces of interest. The decontaminant can be liquid, solid ( powders , wipes

The Microbial Rosetta Stone Database: A compilation of global and emerging infectious microorganisms and bioterrorist threat agents

PubMed Central

Ecker, David J; Sampath, Rangarajan; Willett, Paul; Wyatt, Jacqueline R; Samant, Vivek; Massire, Christian; Hall, Thomas A; Hari, Kumar; McNeil, John A; Büchen-Osmond, Cornelia; Budowle, Bruce

2005-01-01

Background Thousands of different microorganisms affect the health, safety, and economic stability of populations. Many different medical and governmental organizations have created lists of the pathogenic microorganisms relevant to their missions; however, the nomenclature for biological agents on these lists and pathogens described in the literature is inexact. This ambiguity can be a significant block to effective communication among the diverse communities that must deal with epidemics or bioterrorist attacks. Results We have developed a database known as the Microbial Rosetta Stone. The database relates microorganism names, taxonomic classifications, diseases, specific detection and treatment protocols, and relevant literature. The database structure facilitates linkage to public genomic databases. This paper focuses on the information in the database for pathogens that impact global public health, emerging infectious organisms, and bioterrorist threat agents. Conclusion The Microbial Rosetta Stone is available at . The database provides public access to up-to-date taxonomic classifications of organisms that cause human diseases, improves the consistency of nomenclature in disease reporting, and provides useful links between different public genomic and public health databases. PMID:15850481

Select Agent and Toxin Regulations: Beyond the Eighth Edition of the Guide for the Care and Use of Laboratory Animals

PubMed Central

Kastenmayer, Robin J; Moore, Rashida M; Bright, Allison L; Torres-Cruz, Rafael; Elkins, William R

2012-01-01

In the interval between the publication of the seventh and eighth editions of the Guide for the Care and Use of Laboratory Animals (Guide), much has changed with regard to the regulation and funding of highly pathogenic biologic agents and toxins (Select Agents). Funding of research involving highly pathogenic agents has increased dramatically during this time, thus increasing the demand for facilities capable of supporting this work. The eighth edition of the Guide briefly mentions Select Agents and provides a limited set of references. Here we provide some background information regarding the relevant laws and regulations, as well as an overview of the programmatic requirements pertaining to the use of Select Agents, with a focus on use in animals. PMID:22776191

The test chemical selection procedure of the European Centre for the Validation of Alternative Methods for the EU Project ReProTect.

PubMed

Pazos, Patricia; Pellizzer, Cristian; Stummann, Tina C; Hareng, Lars; Bremer, Susanne

2010-08-01

The selection of reference compounds is crucial for a successful in vitro test development in order to proof the relevance of the test system. This publication describes the criteria and the selection strategy leading to a list of more than 130 chemicals suitable for test development within the ReProTect project. The presented chemical inventory aimed to support the development and optimization of in vitro tests that seek to fulfill ECVAM's criteria for entering into the prevalidation. In order to select appropriate substances, a primary database was established compiling information from existing databases. In a second step, predefined selection criteria have been applied to obtain a comprehensive list ready to undergo a peer review process from independent experts with industrial, academic and regulatory background. Finally, a peer reviewed chemical list containing 13 substances challenging endocrine disrupter tests, additional 50 substances serving as reference chemicals for various tests evaluating effects on male and female fertility, and finally 61 substances were identified as known to provoke effects on the early development of mammalian offspring. The final list aims to cover relevant and specific mode/site of actions as they are known to be relevant for various substance classes. However, the recommended list should not be interpreted as a list of reproductive toxicants, because such a description requires proven associations with adverse effects of mammalian reproduction, which are subject of regulatory decisions done by involved competent authorities. Copyright 2010 Elsevier Inc. All rights reserved.

9 CFR 121.3 - VS select agents and toxins.

Code of Federal Regulations, 2010 CFR

2010-01-01

... genetically modified. (d) VS select agents or toxins that meet any of the following criteria are excluded from... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS POSSESSION, USE, AND... recombinant organisms: (1) Nucleic acids that can produce infectious forms of any of the select agent viruses...

Interaction and Communication of Agents in Networks and Language Complexity Estimates

NASA Technical Reports Server (NTRS)

Smid, Jan; Obitko, Marek; Fisher, David; Truszkowski, Walt

2004-01-01

Knowledge acquisition and sharing are arguably the most critical activities of communicating agents. We report about our on-going project featuring knowledge acquisition and sharing among communicating agents embedded in a network. The applications we target range from hardware robots to virtual entities such as internet agents. Agent experiments can be simulated using a convenient simulation language. We analyzed the complexity of communicating agent simulations using Java and Easel. Scenarios we have studied are listed below. The communication among agents can range from declarative queries to sub-natural language queries. 1) A set of agents monitoring an object are asked to build activity profiles based on exchanging elementary observations; 2) A set of car drivers form a line, where every car is following its predecessor. An unsafe distance cm create a strong wave in the line. Individual agents are asked to incorporate and apply directions how to avoid the wave. 3) A set of micro-vehicles form a grid and are asked to propagate information and concepts to a central server.

A Selection of Films for Family Planning Programmes.

ERIC Educational Resources Information Center

International Planned Parenthood Federation, London (England).

This catalog gives an annotated listing of selected films available for use in family planning programs. Films are listed alphabetically, geographically by particular country, and by subject. In most cases information is given concerning length, producer, distributor, cost, and rental conditions from the International Planned Parenthood…

42 CFR 73.4 - Overlap select agents and toxins.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION... its naturally occurring environment provided that the select agent or toxin has not been intentionally... such agent or toxin or destroys the agent or toxin by a recognized sterilization or inactivation...

[Peroral and transdermal application of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of regional musculoskeletal pain syndromes].

PubMed

Hodinka, László; Bálint, Géza; Budai, Erika; Géher, Pál; Papp, Renáta; Somogyi, Péter; Szántó, Sándor; Vereckei, Edit

2017-12-01

In this review the available evidences regarding the most frequently applied medication (peroral and transdermal non-steroidal anti-inflammatory agents) for the most frequent musculoskeletal complaints (regional pain syndromes) have been collected for the appropriate medical professionals who are most frequently faced with these conditions (general practitioners, rheumatologists, orthopedics, occupational and sports medicine experts). The special population at risk (with repeated and high energy overuse because of occupational or sport activities) and the pathology of their syndromes are identified. Mode of action, pharmacological properties of the non-steroidal anti-inflammatory drugs and the unwanted effects of their application especially in infants and elderly are highlighted. Recommendations of the general and specific pain management guidelines have been selected and listed in the review. Orv Hetil. 2017; 158(Suppl. 3): 3-30.

21 CFR 176.200 - Defoaming agents used in coatings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... paragraph (d)(3) and subject to such limitations as are provided: List of substances Limitations n-Butyl... only. Glyceryl mono-12-hydroxystearate Glyceryl monostearate Hexane Hexylene glycol (2-methyl-2,4...

21 CFR 176.200 - Defoaming agents used in coatings.

Code of Federal Regulations, 2013 CFR

2013-04-01

... paragraph (d)(3) and subject to such limitations as are provided: List of substances Limitations n-Butyl... only. Glyceryl mono-12-hydroxystearate Glyceryl monostearate Hexane Hexylene glycol (2-methyl-2,4...

Brandon/Hill selected list of print books and journals in allied health.

PubMed

Hill, Dorothy R; Stickell, Henry N

2003-01-01

This list of 434 books and 79 journals is intended as a selection guide for print literature to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number of and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and recognized by the American Medical Association and other accrediting bodies. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (169 books and 32 journals) are indicated by asterisks. To purchase the entire collection of books and journals (2002 subscriptions) would require an expenditure of about $36,744. The cost of only the asterisked items totals $14,465.

Brandon/Hill selected list of print books and journals in allied health.

PubMed

Hill, D R; Stickell, H N

2000-07-01

This list of 424 books and 77 journals is intended as a selection guide for print literature to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and recognized by the American Medical Association and other accrediting bodies. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (167 books and 31 journals) are indicated by asterisks. To purchase the entire collection of books and journals (2000 subscriptions) would require an expenditure of about $31,970. The cost of only the asterisked items totals $12,515.

Brandon/Hill selected list of print books and journals in allied health*†

PubMed Central

Hill, Dorothy R.; Stickell, Henry N.

2003-01-01

This list of 434 books and 79 journals is intended as a selection guide for print literature to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number of and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and recognized by the American Medical Association and other accrediting bodies. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (169 books and 32 journals) are indicated by asterisks. To purchase the entire collection of books and journals (2002 subscriptions) would require an expenditure of about $36,744. The cost of only the asterisked items totals $14,465. PMID:12568155

Brandon/Hill selected list of print books and journals in allied health*

PubMed Central

Hill, Dorothy R.; Stickell, Henry N.

2000-01-01

This list of 424 books and 77 journals is intended as a selection guide for print literature to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and recognized by the American Medical Association and other accrediting bodies. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (167 books and 31 journals) are indicated by asterisks. To purchase the entire collection of books and journals (2000 subscriptions) would require an expenditure of about $31,970. The cost of only the asterisked items totals $12,515. PMID:10928707

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1987-01-01

The impact that the hospital librarian's use of management techniques and comprehension of the highly competitive health care environment can have on collection development and resulting information services in his or her library is reviewed in the introduction to this revised list of 600 books and 139 journals. The list is intended as a selection guide for the small or medium-size library in a hospital or comparable medical facility, or a core collection for a consortium of small hospital libraries. Books and journals are categorized by subject; the book list is followed by an author/editor index and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by asterisks. To purchase the entire collection of books and to pay for 1987 subscriptions to all journals would require about $52,600. The cost of only the asterisked items totals approximately $21,000. PMID:3594025

Gene selection with multiple ordering criteria.

PubMed

Chen, James J; Tsai, Chen-An; Tzeng, Shengli; Chen, Chun-Houh

2007-03-05

A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two commonly known criteria to select differentially expressed genes under two experimental conditions. These two selection criteria often result in incompatible selected gene sets. Also, in a two-factor, say, treatment by time experiment, the investigator may be interested in one gene list that responds to both treatment and time effects. We propose three layer ranking algorithms, point-admissible, line-admissible (convex), and Pareto, to provide a preference gene list from multiple gene lists generated by different ranking criteria. Using the public colon data as an example, the layer ranking algorithms are applied to the three univariate ranking criteria, fold-change, p-value, and frequency of selections by the SVM-RFE classifier. A simulation experiment shows that for experiments with small or moderate sample sizes (less than 20 per group) and detecting a 4-fold change or less, the two-dimensional (p-value and fold-change) convex layer ranking selects differentially expressed genes with generally lower FDR and higher power than the standard p-value ranking. Three applications are presented. The first application illustrates a use of the layer rankings to potentially improve predictive accuracy. The second application illustrates an application to a two-factor experiment involving two dose levels and two time points. The layer rankings are applied to selecting differentially expressed genes relating to the dose and time effects. In the third application, the layer rankings are applied to a benchmark data set consisting of three dilution concentrations to provide a ranking system from a long list of differentially expressed genes generated from the three dilution concentrations. The layer ranking algorithms are useful to help investigators in selecting the most promising genes from multiple gene lists generated by different filter, normalization, or analysis methods for various objectives.

[Impact of potentially inappropriate drug usage on health insurance business results].

PubMed

Kirschke, Malin; Böhme, Jacqueline

2014-09-01

In Germany a list was drawn up that included 83 potentially inappropriate drugs. The PRISCUS list published in 2010 was intended to highlight certain problems in the pharmakotherapy of elderly patients and serve as a support for improved medicine safety. Almost a third of the insurance portfolio of the HALLESCHE Krankenversicherung aged over 75 years takes drugs that are on the PRISCUS list. Benzodiazepine and Z-drugs are taken most frequently. The costs per insurant with potentially inappropriate medication are on average higher than for policyholders who do not take drugs on the PRISCUS list. The costs per insurant are rising, with an increase in the number of PRISCUS agents being taken as well. However, there is still no scientific proof that potentially inappropriate drugs lead to adverse drug events.

42 CFR 73.4 - Overlap select agents and toxins.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION... its naturally occurring environment provided that the select agent or toxin has not been intentionally... an entity eligible to receive such agent or toxin or destroys the agent or toxin by a recognized...

Advisory List of Reference Books for Grades K-6.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Educational Media.

Intended to serve as a guide rather than as a comprehensive listing, this advisory list includes reference books appropriate for school media collections for grades K-6. Entries included on the list were selected from those materials submitted by publishers which received favorable reviews by educators. Single volumes and sets of books are listed…

Alpha-beta coordination method for collective search

DOEpatents

Goldsmith, Steven Y.

2002-01-01

The present invention comprises a decentralized coordination strategy called alpha-beta coordination. The alpha-beta coordination strategy is a family of collective search methods that allow teams of communicating agents to implicitly coordinate their search activities through a division of labor based on self-selected roles and self-determined status. An agent can play one of two complementary roles. An agent in the alpha role is motivated to improve its status by exploring new regions of the search space. An agent in the beta role is also motivated to improve its status, but is conservative and tends to remain aggregated with other agents until alpha agents have clearly identified and communicated better regions of the search space. An agent can select its role dynamically based on its current status value relative to the status values of neighboring team members. Status can be determined by a function of the agent's sensor readings, and can generally be a measurement of source intensity at the agent's current location. An agent's decision cycle can comprise three sequential decision rules: (1) selection of a current role based on the evaluation of the current status data, (2) selection of a specific subset of the current data, and (3) determination of the next heading using the selected data. Variations of the decision rules produce different versions of alpha and beta behaviors that lead to different collective behavior properties.

The Composites Institute`s FirstSource directory

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-31

This book is the gateway to the composites industry, containing pertinent phone numbers along with a glossary of terms. The glossary is a complete listing of current composites terminology and their definitions, from Ablative Plastic to Young`s Modulus. Contents include: (1) corporate index; (2) manufacturing processes; (3) materials suppliers; (4) markets--parts/products/components; (5) tooling; (6) processing equipment and supplies; (7) distributors/agents; (8) consulting, testing and other services; (9) geographical listing; and (10) glossary.

Update on Banned Substances 2013

PubMed Central

Barnes, Kenneth P.; Rainbow, Catherine R.

2013-01-01

Context: Doping has been pervasive throughout the history of athletic competitions and has only recently been regulated by organizations such as the World Anti-Doping Agency (WADA), US Anti-Doping Agency (USADA), and the National Collegiate Athletic Association (NCAA). These regulatory bodies were created to preserve fair play and maintain the safety of the participants. Their updated 2013 lists of banned substances and practices include a variety of drugs and practices that could cause harm to an athlete or give one an unfair competitive advantage. Evidence Acquisition: Published websites for the WADA, USADA, and NCAA were investigated. These governing bodies update and publish their lists annually. Results: The WADA, USADA, and NCAA monitor anabolic steroids, hormones, growth factors, β-agonists, hormone and metabolic modulators, masking agents, street drugs, manipulation of blood and blood components, chemical and physical manipulation, gene doping, stimulants, narcotics, glucocorticosteroids, and β-blockers. Some substances may be used by athletes but require formal exemption. The WADA has also recently created a category of nonapproved substances that have yet to be identified to curb athletes from experimenting with new doping agents. Conclusion: The lists of banned substances and practices per the WADA, USADA, and NCAA are in place to ensure the integrity of sports and maintain safe competition. Health care providers who work with athletes under the jurisdiction of these organizations should review updated lists of banned substances when prescribing medications. PMID:24427415

Public Administration: A Bibliography of Selected Reference Sources.

ERIC Educational Resources Information Center

Brustman, Mary Jane

This guide presents an annotated list of selected reference sources in public administration. All of the sources listed are found at the Graduate Library for Public Affairs and Policy (GLPP) located at the State University of New York, Albany. Detailed, exhaustive guides in literature, research, indexes, abstracts, statistical sources, government…

Index to Positions: A Selective List, 1969-1982.

ERIC Educational Resources Information Center

Staniford, Edward; Conn, Edith

Positions taken by the Academic Senate for California Community Colleges (ASCCC) on selected topics are traced over the years 1969 through 1982. Chronological listings of ASCCC positions are provided for the following topics as compiled in 1980: academic standards, accreditation, credit and noncredit course policy, general education, grade policy,…

Nitrosoureas: a review of experimental antitumor activity.

PubMed

Schabel, F M

1976-06-01

The chemical class of drugs known as the nitrosoureas are a recently developed group of very active alkylating-agent anticancer drugs which are best represented by BCNU, CCNU, and methyl-CCNU (meCCNU). The nitrosoureas are among the most active, if not the most active, anticancer drugs both quantitatively (log kill of sensitive tumor cells in vivo) and qualitatively (spectrum of mouse, rat, and hamster tumors responding to treatment). Therapeutic anticancer activity of the nitrosoureas has been consistently observed with oral as well as parenteral administration. The nitrosoureas are clearly the most active group of anticancer drugs observed against experimental meningeal leukemias and intracerebrally implanted transplantable primary tumors of central nervous system origin (eg, gliomas, ependymoblastomas, and astrocytomas in mice and hamsters). The nitrosoureas have been observed to be less than additive in lethal toxicity for vital normal cells in the mouse in combination with representatives of the other major classes of anticancer agents, eg, purine antagonists, pyrimidine antagonists, inhibitors of DNA polymerase(s) or ribonucleotide reductase(s), mitotic inhibitors, drugs that bind to or intercalate with DNA, and other alkylating agents. Therapeutic synergism against one or more transplantable or spontaneous tumors of mice, rats, or hamsters with one of several nitrosoureas in two-drug combinations with representatives of most of the major classes of anticancer agents listed above has been reported. With a number of advanced-stages mouse tumors, generally considered to be refractory to treatment with most anticancer agents, long-term cures have been obtained with combination-drug or combined-modality (surgery plus chemotherapy) treatment. The demonstrated lack of cross-resistance of several leukemias and solid tumors of mice selected for resistance to BCNU, meCCNU, or other alkylating agents suggests that the widely held opinion that all alkylating agents are very similar in biologic mechanism of action, and therefore resistance to one alkylating agent probably predicts cross-resistance to all alkylating agents, may no longer be tenable. If not, then alkylating-agent drug combinations, either used alone or combined with other treatment modalities (eg, surgery) which have been reported to result in therapeutic improvement in a number of experimental murine tumor systems, may be indicated for serious consideration as surgical adjuvant chemotherapy by surgeons or as primary therapy by medical oncologists.

7 CFR 331.10 - Restricting access to select agents and toxins; security risk assessments.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; security risk assessments. 331.10 Section 331.10 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE POSSESSION, USE, AND TRANSFER OF SELECT AGENTS AND TOXINS § 331.10 Restricting access to select agents and toxins; security risk...

42 CFR 73.5 - Exemptions for HHS select agents and toxins.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days after...

42 CFR 73.5 - Exemptions for HHS select agents and toxins.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days after...

9 CFR 121.6 - Exemptions for overlap select agents and toxins.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Exemptions for overlap select agents and toxins. 121.6 Section 121.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... select agent or toxin that is contained in a specimen presented for proficiency testing will be exempt...

9 CFR 121.6 - Exemptions for overlap select agents and toxins.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Exemptions for overlap select agents and toxins. 121.6 Section 121.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... select agent or toxin that is contained in a specimen presented for proficiency testing will be exempt...

Nitric oxide donors for cervical ripening and induction of labour.

PubMed

Kelly, Anthony J; Munson, Christopher; Minden, Lucy

2011-06-15

Sometimes it is necessary to bring on labour artificially because of safety concerns for the mother or baby. This review is one of a series of reviews of methods of labour induction using a standardised protocol.Induction of labour occurs in approximately 20% of pregnancies in the UK. The ideal agent for induction of labour would induce cervical ripening without causing uterine contractions. Currently most commonly used cervical ripening or induction agents result in uterine activity or contractions, or both. Cervical ripening without uterine contractility could occur safely in an outpatient setting and it may be expected that this would result in greater maternal satisfaction and lower costs. To determine the effects of nitric oxide (NO) donors for third trimester cervical ripening or induction of labour, in comparison with placebo or no treatment or other treatments from a predefined hierarchy. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 December 2010) and the reference lists of trial reports and reviews. Clinical trials comparing NO donors for cervical ripening or labour induction to other methods listed above it on a predefined list of methods of labour induction. The trials include some form of random allocation to either group; and report one or more of the prestated outcomes. NO donors (isosorbide mononitrate, nitroglycerin and sodium nitroprusside) are compared to other methods listed above it on a predefined list of methods of labour induction. This review is part of a series of reviews focusing on methods of induction of labour. Three review authors independently assessed trials for inclusion, assessed risk of bias and extracted data. We considered 19 trials; we included 10 (including a total of 1889 women) trials, excluded eight trials and one trial report is awaiting classification. Included studies compared NO donors to placebo, vaginal prostaglandin E2, intracervical PGE2 and vaginal misoprostol. All included studies were of a generally high standard with a low risk of bias.There are very limited data available to compare nitric oxide donors to any other induction agent. There is no evidence of any difference between any of the prespecified outcomes when comparing NO donors to other induction agents, with the exception of an increase in maternal side effects. NO donors do not appear currently to be a useful tool in the process of induction of labour. More studies are required to examine how NO donors may work alongside established induction of labour protocols, especially those based in outpatient settings.

Opportunities for Web-based Drug Repositioning: Searching for Potential Antihypertensive Agents with Hypotension Adverse Events.

PubMed

Wang, Kejian; Wan, Mei; Wang, Rui-Sheng; Weng, Zuquan

2016-04-01

Drug repositioning refers to the process of developing new indications for existing drugs. As a phenotypic indicator of drug response in humans, clinical side effects may provide straightforward signals and unique opportunities for drug repositioning. We aimed to identify drugs frequently associated with hypotension adverse reactions (ie, the opposite condition of hypertension), which could be potential candidates as antihypertensive agents. We systematically searched the electronic records of the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) through the openFDA platform to assess the association between hypotension incidence and antihypertensive therapeutic effect regarding a list of 683 drugs. Statistical analysis of FAERS data demonstrated that those drugs frequently co-occurring with hypotension events were more likely to have antihypertensive activity. Ranked by the statistical significance of frequent hypotension reporting, the well-known antihypertensive drugs were effectively distinguished from others (with an area under the receiver operating characteristic curve > 0.80 and a normalized discounted cumulative gain of 0.77). In addition, we found a series of antihypertensive agents (particularly drugs originally developed for treating nervous system diseases) among the drugs with top significant reporting, suggesting the good potential of Web-based and data-driven drug repositioning. We found several candidate agents among the hypotension-related drugs on our list that may be redirected for lowering blood pressure. More important, we showed that a pharmacovigilance system could alternatively be used to identify antihypertensive agents and sustainably create opportunities for drug repositioning.

The 50 Constellation Priority Sites

NASA Technical Reports Server (NTRS)

Noble, S.; Joosten, K.; Eppler, D.; Gruener, J.; Mendell, W.; French, R.; Plescia, J.; Spudis, P.; Wargo, M.; Robinson, M.;

What's New in Children's Literature for the Children of Louisiana? A Selected Annotated Bibliography with Readability Levels (Selected) and Associated Louisiana Content Standards

ERIC Educational Resources Information Center

Webre, Elizabeth C.

2011-01-01

An annotated list of children's books published within the last 15 years and related to Louisiana culture, environment, and economics are linked to the Louisiana Content Standards. Readability levels of selected books are included, providing guidance as to whether a book is appropriate for independent student use. The thirty-three books listed are…

48 CFR 511.603 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... symbol from the DoD Master Urgency List and may only do so when GSA is acting as the procuring agent for... follow all the provisions of the Defense Priorities and Allocations System regulation (15 CFR part 700...

Sertraline versus other antidepressive agents for depression

PubMed Central

Cipriani, Andrea; La Ferla, Teresa; Furukawa, Toshi A; Signoretti, Alessandra; Nakagawa, Atsuo; Churchill, Rachel; McGuire, Hugh; Barbui, Corrado

2014-01-01

Background The National Institute for Health and Clinical Excellence clinical practice guideline on the treatment of depressive disorder recommended that selective serotonin reuptake inhibitors should be the first-line option when drug therapy is indicated for a depressive episode. Preliminary evidence suggested that sertraline might be slightly superior in terms of effectiveness. Objectives To assess the evidence for the efficacy, acceptability and tolerability of sertraline in comparison with tricyclics (TCAs), heterocyclics, other SSRIs and newer agents in the acute-phase treatment of major depression. Search methods MEDLINE (1966 to 2008), EMBASE (1974 to 2008), the Cochrane Collaboration Depression, Anxiety and Neurosis Controlled Trials Register and the Cochrane Central Register of Controlled Trials up to July 2008. No language restriction was applied. Reference lists of relevant papers and previous systematic reviews were hand-searched. Pharmaceutical companies and experts in this field were contacted for supplemental data. Selection criteria Randomised controlled trials allocating patients with major depression to sertraline versus any other antidepressive agent. Data collection and analysis Two review authors independently extracted data. Discrepancies were resolved with another member of the team. A double-entry procedure was employed by two reviewers. Information extracted included study characteristics, participant characteristics, intervention details and outcome measures in terms of efficacy (the number of patients who responded or remitted), acceptability (the number of patients who failed to complete the study) and tolerability (side-effects). Main results A total of 59 studies, mostly of low quality, were included in the review, involving multiple treatment comparisons between sertraline and other antidepressant agents. Evidence favouring sertraline over some other antidepressants for the acute phase treatment of major depression was found, either in terms of efficacy (fluoxetine) or acceptability/tolerability (amitriptyline, imipramine, paroxetine and mirtazapine). However, some differences favouring newer antidepressants in terms of efficacy (mirtazapine) and acceptability (bupropion) were also found. In terms of individual side effects, sertraline was generally associated with a higher rate of participants experiencing diarrhoea. Authors’ conclusions This systematic review and meta-analysis highlighted a trend in favour of sertraline over other antidepressive agents both in terms of efficacy and acceptability, using 95% confidence intervals and a conservative approach, with a random effects analysis. However, the included studies did not report on all the outcomes that were pre-specified in the protocol of this review. Outcomes of clear relevance to patients and clinicians were not reported in any of the included studies. PMID:20393946

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The bibliography contains citations concerning the use of biological agents to control insects and pests. Radiation, genetic breeding, bacteria, fungi, viruses, and pheromones are discussed as alternatives to pesticidal management. Methods for monitoring the effectiveness and environmental impact of these agents are reviewed. Population control of fruit flies, spruce sawflies, flies, mosquitoes, cockroaches, gypsy moths, and other agriculturally-important insects is also discussed. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

Recipient selection process and listing for lung transplantation

PubMed Central

Dupont, Lieven; Yserbyt, Jonas; Schaevers, Veronique; Van Raemdonck, Dirk; Neyrinck, Arne; Vos, Robin

2017-01-01

Lung transplantation remains the ultimate treatment option for selected patients with end-stage (cardio) pulmonary disease. Given the current organ shortage, it is without any doubt that careful selection of potential transplant candidates is essential as this may greatly influence survival after the procedure. In this paper, we will review the current guidelines for referral and listing of lung transplant candidates in general, and in more depth for the specific underlying diseases. Needless to state that these are not absolute guidelines, and that decisions depend upon center’s activity, waiting list, etc. Therefore, every patient should be discussed with the transplant center before any definite decision is made to accept or decline a patient for lung transplantation. PMID:29221322

Priority Medicines for Maternal and Child Health: A Global Survey of National Essential Medicines Lists

PubMed Central

Hill, Suzanne; Yang, Annie; Bero, Lisa

2012-01-01

Background In April 2011, the World Health Organization (WHO) published a list of “priority medicines” for maternal and child health based on 1) the global burden of disease and 2) evidence of efficacy and safety. The objective of this study was to examine the occurrence of these priority medicines on national essential medicines lists. Methods and Findings All essential medicines lists published since 1999 were selected from the WHO website collection. The most-up-to date list for each country was then selected, resulting in 89 unique country lists. Each list was evaluated for inclusion of medicines (chemical entity, concentration, and dosage form) on the Priority Medicines List. There was global variation in the listing of the Priority Medicines. The most frequently listed medicine was paracetamol, on 94% (84/89) of lists. Sodium chloride, gentamicin and oral rehydration solution were on 93% (83/89) of lists. The least frequently listed medicine was the children's antimalarial rectal artesunate, on 8% of lists (7/89); artesunate injection was on 16% (14/89) of lists. Pediatric artemisinin combination therapy, as dispersible tablets or flexible oral solid dosage form, appeared on 36% (32/89) of lists. Procaine benzylpenicillin, for treatment of pediatric pneumonia and neonatal sepsis, was on 50% (45/89) of the lists. Zinc, for treatment of diarrhoea in children, was included on only 15% (13/89) of lists. For prevention and treatment of postpartum hemorrhage in women, oxytocin was more prevalent on the lists than misoprostol; they were included on 55 (62%) and 31 (35%) of lists, respectively. Cefixime, for treatment of uncomplicated anogenital gonococcal infection in woman was on 26% (23/89) of lists. Magnesium sulfate injection for treatment of severe pre-eclampsia and eclampsia was on 50% (45/89) of the lists. Conclusions The findings suggest that countries need to urgently amend their lists to provide all priority medicines as part of the efforts to improve maternal and child health. PMID:22675435

Agent Reward Shaping for Alleviating Traffic Congestion

NASA Technical Reports Server (NTRS)

Tumer, Kagan; Agogino, Adrian

2006-01-01

Traffic congestion problems provide a unique environment to study how multi-agent systems promote desired system level behavior. What is particularly interesting in this class of problems is that no individual action is intrinsically "bad" for the system but that combinations of actions among agents lead to undesirable outcomes, As a consequence, agents need to learn how to coordinate their actions with those of other agents, rather than learn a particular set of "good" actions. This problem is ubiquitous in various traffic problems, including selecting departure times for commuters, routes for airlines, and paths for data routers. In this paper we present a multi-agent approach to two traffic problems, where far each driver, an agent selects the most suitable action using reinforcement learning. The agent rewards are based on concepts from collectives and aim to provide the agents with rewards that are both easy to learn and that if learned, lead to good system level behavior. In the first problem, we study how agents learn the best departure times of drivers in a daily commuting environment and how following those departure times alleviates congestion. In the second problem, we study how agents learn to select desirable routes to improve traffic flow and minimize delays for. all drivers.. In both sets of experiments,. agents using collective-based rewards produced near optimal performance (93-96% of optimal) whereas agents using system rewards (63-68%) barely outperformed random action selection (62-64%) and agents using local rewards (48-72%) performed worse than random in some instances.

Influence of Selected Personal Characteristics and County Situational Factors on Time Allocated to Dairy Subjects by Extension Agents in Selected Tennessee Counties.

ERIC Educational Resources Information Center

Northcutt, Sherwin Dean; And Others

The study deals with various predictors of time spent on dairy subjects by Extension agents and predictors of contacts made by agents with dairy clientele. Purposes were to determine the relationships, if any, between various independent variables and groups of independent variables (agents' background and training, county dairy situation, agents'…

A Basic Vocabulary and a Bibliography for Scientific and Technical English.

ERIC Educational Resources Information Center

Brunt, Richard J.

The selection of 594 words in this basic vocabulary list was compiled from various dictionaries and frequency lists for physics, mathematics and civil engineering. The list attempts to include those words which have been found to be unknown by German students learning English for science and technology. In addition to the word list, a bibliography…

Contribution of Selective Conditions to Microbial Competition in Four Listeria Selective Enrichment Formulations

PubMed Central

Keys, Ashley L.; Hitchins, Anthony D.; Smiley, R. Derike

2017-01-01

Microbial competition during selective enrichment negatively affects Listeria monocytogenes populations and may hinder the subsequent detection or recovery of this organism. Competition assays among 10 selected strains of Listeria and Citrobacter braakii were performed in buffered Listeria enrichment broth, 3-(N-morpholino)propanesulfonic acid–buffered Listeria enrichment broth, University of Vermont medium–modified Listeria enrichment broth, and Fraser broth. The individual contributions of each selective agent in these media were also assessed, as well as the contribution of incubation temperature. Acriflavine hydrochloride and sodium nalidixate were ineffective at preventing the overgrowth of C. braakii; this resulted in substantially lower populations of Listeria than when the competitor was absent. At the higher levels, both of these selective agents were detrimental to Listeria populations. The highest enrichment populations of Listeria were observed when either NaCl or LiCl was present. In the absence of selective agents, the final populations of Listeria following competitive growth with C. braakii were not substantially affected by temperature; however, in the presence of selective agents, the Listeria populations were statistically higher at the higher incubation temperature. There are a limited number of selective agents available for use in Listeria-specific enrichment media, resulting in formulations that are only somewhat selective for this species. The optimization of current formulations may help researchers to improve Listeria recovery, particularly from products with a high microbial load. The understanding of the behavior and interactions between target and nontarget microorganisms in the presence of these available selective agents is a necessary step in the optimization of Listeria selective enrichment formulations. PMID:28221922

Contribution of Selective Conditions to Microbial Competition in Four Listeria Selective Enrichment Formulations.

PubMed

Keys, Ashley L; Hitchins, Anthony D; Smiley, R Derike

2016-11-01

Microbial competition during selective enrichment negatively affects Listeria monocytogenes populations and may hinder the subsequent detection or recovery of this organism. Competition assays among 10 selected strains of Listeria and Citrobacter braakii were performed in buffered Listeria enrichment broth, 3-(N-morpholino)propanesulfonic acid-buffered Listeria enrichment broth, University of Vermont medium-modified Listeria enrichment broth, and Fraser broth. The individual contributions of each selective agent in these media were also assessed, as well as the contribution of incubation temperature. Acriflavine hydrochloride and sodium nalidixate were ineffective at preventing the overgrowth of C. braakii ; this resulted in substantially lower populations of Listeria than when the competitor was absent. At the higher levels, both of these selective agents were detrimental to Listeria populations. The highest enrichment populations of Listeria were observed when either NaCl or LiCl was present. In the absence of selective agents, the final populations of Listeria following competitive growth with C. braakii were not substantially affected by temperature; however, in the presence of selective agents, the Listeria populations were statistically higher at the higher incubation temperature. There are a limited number of selective agents available for use in Listeria -specific enrichment media, resulting in formulations that are only somewhat selective for this species. The optimization of current formulations may help researchers to improve Listeria recovery, particularly from products with a high microbial load. The understanding of the behavior and interactions between target and nontarget microorganisms in the presence of these available selective agents is a necessary step in the optimization of Listeria selective enrichment formulations.

Recordings for Children. A Selected List of Records and Cassettes. Fourth Edition.

ERIC Educational Resources Information Center

Thomas, Elaine E., Comp.; And Others

This booklet, compiled by three experts in children's recordings, provides a selected list of records and cassettes which can accommodate a broad range of informational and recreational requirements of children. Some of the subjects covered are children's songs and folk music, orchestral music, popular music, holidays, natural sciences and space…

American Folk Music and Folklore Recordings 1984: A Selected List.

ERIC Educational Resources Information Center

Library of Congress, Washington, DC. American Folklife Center.

In an effort to encourage appreciation of the rich folk heritage of the United States, the American Folklife Center of the Library of Congress presents this annual list of 30 recordings selected by a panel of distinguished experts from nearly two hundred titles submitted by producers, suggested by folklorists and ethnomusicologists, and proposed…

Selected Research Tools in Economics, Labor and Industrial Relations.

ERIC Educational Resources Information Center

Kaye, Ronald J.

Twenty-two indexing and abstracting services and general reference sources in the areas of labor and industrial relations are listed in this selective bibliography for users of State University of New York at Albany Libraries. Classification numbers are included for each source and most have annotations. Materials are listed under four…

Reference Guide for Teaching Selected Duty Areas from Business, Marketing and Management Occupations.

ERIC Educational Resources Information Center

Rich, John H.

This reference guide was designed to assist business, marketing, and management educators in locating textbook/instructional materials for use in teaching duty areas and task lists for grades 11-14. Duty areas and task lists are matched with selected textbook/instructional publications for the secretarial, general office clerk, and information…

RADIOISOTOPES IN MEDICINE AND HUMAN PHYSIOLOGY. A Selected List of References

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCormick, J.A. comp.

1958-08-01

This bibliography contains 2862 references on uses of radioisotopes in diagnostic medicine, therapeutic medicine, clinical research, human physiology, general medical research, and immunology. The references were taken from the 1948 to 1956 open literature. A list of the journals from which the references were selected and an author index are included. (auth)'

Automatic Text Analysis Based on Transition Phenomena of Word Occurrences

ERIC Educational Resources Information Center

Pao, Miranda Lee

1978-01-01

Describes a method of selecting index terms directly from a word frequency list, an idea originally suggested by Goffman. Results of the analysis of word frequencies of two articles seem to indicate that the automated selection of index terms from a frequency list holds some promise for automatic indexing. (Author/MBR)

Food and Nutrition Supplementary Resources: A Selective Annotated Bibliography for Elementary Schools, K-6.

ERIC Educational Resources Information Center

Minnesota State Dept. of Education, St. Paul. Child Nutrition Section.

This selected bibliography provides elementary school educators with a list of books currently in print which provide supplementary resources on food, nutrition and related topics. All books listed were judged factually accurate and suitable for the grade level designated, offering material that would implement, enrich and support elementary…

Encyclopedia of software components

NASA Technical Reports Server (NTRS)

Vanwarren, Lloyd (Inventor); Beckman, Brian C. (Inventor)

1991-01-01

Intelligent browsing through a collection of reusable software components is facilitated with a computer having a video monitor and a user input interface such as a keyboard or a mouse for transmitting user selections, by presenting a picture of encyclopedia volumes with respective visible labels referring to types of software, in accordance with a metaphor in which each volume includes a page having a list of general topics under the software type of the volume and pages having lists of software components for each one of the generic topics, altering the picture to open one of the volumes in response to an initial user selection specifying the one volume to display on the monitor a picture of the page thereof having the list of general topics and altering the picture to display the page thereof having a list of software components under one of the general topics in response to a next user selection specifying the one general topic, and then presenting a picture of a set of different informative plates depicting different types of information about one of the software components in response to a further user selection specifying the one component.

Encyclopedia of Software Components

NASA Technical Reports Server (NTRS)

Warren, Lloyd V. (Inventor); Beckman, Brian C. (Inventor)

1997-01-01

Intelligent browsing through a collection of reusable software components is facilitated with a computer having a video monitor and a user input interface such as a keyboard or a mouse for transmitting user selections, by presenting a picture of encyclopedia volumes with respective visible labels referring to types of software, in accordance with a metaphor in which each volume includes a page having a list of general topics under the software type of the volume and pages having lists of software components for each one of the generic topics, altering the picture to open one of the volumes in response to an initial user selection specifying the one volume to display on the monitor a picture of the page thereof having the list of general topics and altering the picture to display the page thereof having a list of software components under one of the general topics in response to a next user selection specifying the one general topic, and then presenting a picture of a set of different informative plates depicting different types of information about one of the software components in response to a further user selection specifying the one component.

The 'wise list'- a comprehensive concept to select, communicate and achieve adherence to recommendations of essential drugs in ambulatory care in Stockholm.

PubMed

Gustafsson, Lars L; Wettermark, Björn; Godman, Brian; Andersén-Karlsson, Eva; Bergman, Ulf; Hasselström, Jan; Hensjö, Lars-Olof; Hjemdahl, Paul; Jägre, Ingrid; Julander, Margaretha; Ringertz, Bo; Schmidt, Daniel; Sjöberg, Susan; Sjöqvist, Folke; Stiller, Carl-Olav; Törnqvist, Elisabeth; Tryselius, Rolf; Vitols, Sigurd; von Bahr, Christer

2011-04-01

The aim was to present and evaluate the impact of a comprehensive strategy over 10 years to select, communicate and achieve adherence to essential drug recommendations (EDR) in ambulatory care in a metropolitan healthcare region. EDRs were issued and launched as a 'Wise List' by the regional Drug and Therapeutics Committee in Stockholm. This study presents the concept by: (i) documenting the process for selecting, communicating and monitoring the impact of the 'Wise List'; (ii) analysing the variation in the number of drug substances recommended between 2000 and 2010; (iii) assessing the attitudes to the 'Wise List' among prescribers and the public; (iv) evaluating the adherence to recommendations between 2003 and 2009. The 'Wise List' consistently contained 200 drug substances for treating common diseases. The drugs were selected based on their efficacy, safety, suitability and cost-effectiveness. The 'Wise List' was known among one-third of a surveyed sample of the public in 2002 after initial marketing campaigns. All surveyed prescribers knew about the concept and 81% found the recommendations trustworthy in 2005. Adherence to recommendations increased from 69% in 1999 to 77% in 2009. In primary care, adherence increased from 83% to 87% from 2003 to 2009. The coefficient of variation (CV%) decreased from 6.1% to 3.8% for 156 healthcare centres between these years. The acceptance of the 'Wise List' in terms of trust among physicians and among the public and increased adherence may be explained by clear criteria for drug recommendations, a comprehensive communication strategy, electronic access to recommendations, continuous medical education and involvement of professional networks and patients.

76 FR 8388 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change To List...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

.... The Bank of New York Mellon Corporation is the administrator, Fund accountant, transfer agent and... policies, distributions and taxes, availability of information, trading rules and halts, and surveillance...

National Contingency Plan (NCP) Subpart J Product Schedule Fact Sheet

EPA Pesticide Factsheets

This section of the National Oil and Hazardous Substances Pollution Contingency Plan stipulates the criteria for listing and managing the use of dispersants and other chemical and biological agents used to mitigate oil spills.

49 CFR 92.19 - Obtaining the services of a hearing official.

Code of Federal Regulations, 2010 CFR

2010-10-01

... operating element is the creditor agency, the chief of the appropriate accounting or finance office shall.... (This appendix lists the agents designated to accept legal process for the executive branch, the U.S...

15 CFR 16.14 - Annual report.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Commerce and Foreign Trade Office of the Secretary of Commerce PROCEDURES FOR A VOLUNTARY CONSUMER PRODUCT... under the program, including an evaluation of the program and a list of participants, designated agents, and types of consumer products covered. ...

21 CFR 207.40 - Establishment registration and drug listing requirements for foreign establishments.

Code of Federal Regulations, 2011 CFR

2011-04-01

... part 312 of this chapter, or the investigational new animal drug use provisions in part 511 of this... agent shall assist FDA in communications with the foreign drug establishment, respond to questions...

21 CFR 207.40 - Establishment registration and drug listing requirements for foreign establishments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... part 312 of this chapter, or the investigational new animal drug use provisions in part 511 of this... agent shall assist FDA in communications with the foreign drug establishment, respond to questions...

5 CFR Appendix A to Part 581 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2014 CFR

2014-01-01

... Bldg., 210 Walnut Street, Des Moines, IA 50309, (515) 284-4588 Human Resources Officer, Natural..., (303) 969-7739 Department of Justice Offices, Boards, and Divisions Personnel Group/Payroll Operations...

5 CFR Appendix A to Part 581 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2010 CFR

2010-01-01

... Bldg., 210 Walnut Street, Des Moines, IA 50309, (515) 284-4588 Human Resources Officer, Natural..., (303) 969-7739 Department of Justice Offices, Boards, and Divisions Personnel Group/Payroll Operations...

5 CFR Appendix A to Part 581 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2013 CFR

2013-01-01

... Bldg., 210 Walnut Street, Des Moines, IA 50309, (515) 284-4588 Human Resources Officer, Natural..., (303) 969-7739 Department of Justice Offices, Boards, and Divisions Personnel Group/Payroll Operations...

5 CFR Appendix A to Part 581 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2012 CFR

2012-01-01

... Bldg., 210 Walnut Street, Des Moines, IA 50309, (515) 284-4588 Human Resources Officer, Natural..., (303) 969-7739 Department of Justice Offices, Boards, and Divisions Personnel Group/Payroll Operations...

5 CFR Appendix A to Part 581 - List of Agents Designated To Accept Legal Process

Code of Federal Regulations, 2011 CFR

2011-01-01

... Bldg., 210 Walnut Street, Des Moines, IA 50309, (515) 284-4588 Human Resources Officer, Natural..., (303) 969-7739 Department of Justice Offices, Boards, and Divisions Personnel Group/Payroll Operations...

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.

PubMed

Magiorakos, A-P; Srinivasan, A; Carey, R B; Carmeli, Y; Falagas, M E; Giske, C G; Harbarth, S; Hindler, J F; Kahlmeter, G; Olsson-Liljequist, B; Paterson, D L; Rice, L B; Stelling, J; Struelens, M J; Vatopoulos, A; Weber, J T; Monnet, D L

2012-03-01

Many different definitions for multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) bacteria are being used in the medical literature to characterize the different patterns of resistance found in healthcare-associated, antimicrobial-resistant bacteria. A group of international experts came together through a joint initiative by the European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC), to create a standardized international terminology with which to describe acquired resistance profiles in Staphylococcus aureus, Enterococcus spp., Enterobacteriaceae (other than Salmonella and Shigella), Pseudomonas aeruginosa and Acinetobacter spp., all bacteria often responsible for healthcare-associated infections and prone to multidrug resistance. Epidemiologically significant antimicrobial categories were constructed for each bacterium. Lists of antimicrobial categories proposed for antimicrobial susceptibility testing were created using documents and breakpoints from the Clinical Laboratory Standards Institute (CLSI), the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the United States Food and Drug Administration (FDA). MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories, XDR was defined as non-susceptibility to at least one agent in all but two or fewer antimicrobial categories (i.e. bacterial isolates remain susceptible to only one or two categories) and PDR was defined as non-susceptibility to all agents in all antimicrobial categories. To ensure correct application of these definitions, bacterial isolates should be tested against all or nearly all of the antimicrobial agents within the antimicrobial categories and selective reporting and suppression of results should be avoided. © 2011 European Society of Clinical Microbiology and Infectious Diseases. No claim to original US government works.

Identifying occupational carcinogens: an update from the IARC Monographs.

PubMed

Loomis, Dana; Guha, Neela; Hall, Amy L; Straif, Kurt

2018-05-16

The recognition of occupational carcinogens is important for primary prevention, compensation and surveillance of exposed workers, as well as identifying causes of cancer in the general population. This study updates previously published lists of known occupational carcinogens while providing additional information on cancer type, exposure scenarios and routes, and discussing trends in the identification of carcinogens over time. Data were extracted from International Agency for Research on Cancer (IARC) Monographs covering the years 1971-2017, using specific criteria to ensure occupational relevance and provide high confidence in the causality of observed exposure-disease associations. Selected agents were substances, mixtures or types of radiation classified in IARC Group 1 with 'sufficient evidence of carcinogenicity' in humans from studies of exposed workers and evidence of occupational exposure documented in the pertinent monograph. The number of known occupational carcinogens has increased over time: 47 agents were identified as known occupational carcinogens in 2017 compared with 28 in 2004. These estimates are conservative and likely underestimate the number of carcinogenic agents present in workplaces. Exposure to these agents causes a wide range of cancers; cancers of the lung and other respiratory sites, followed by skin, account for the largest proportion. The dominant routes of exposure are inhalation and dermal contact. Important progress has been made in identifying occupational carcinogens; nevertheless, there is an ongoing need for research on the causes of work-related cancer. Most workplace exposures have not been evaluated for their carcinogenic potential due to inadequate epidemiologic evidence and a paucity of quantitative exposure data. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

JPL preferred parts list: Reliable electronic components

NASA Technical Reports Server (NTRS)

Covey, R. E.; Scott, W. R.; Hess, L. M.; Steffy, T. G.; Stott, F. R.

1982-01-01

The JPL Preferred Parts List was prepared to provide a basis for selection of electronic parts for JPL spacecraft programs. Supporting tests for the listed parts were designed to comply with specific spacecraft environmental requirements. The list tabulates the electronic, magnetic, and electromechanical parts applicable to all JPL electronic equipment wherein reliability is a major concern. The parts listed are revelant to equipment supplied by subcontractors as well as fabricated at the laboratory.

Review of Restricted Experiment Requests, Division of Select Agents and Toxins, Centers for Disease Control and Prevention, 2006-2013.

PubMed

Smith, Jacinta; Gangadharan, Denise; Weyant, Robbin

2015-01-01

The Centers for Disease Control and Prevention (CDC) Division of Select Agents and Toxins (DSAT) regulates laboratories that possess, use, or transfer select agents and toxins in the United States. DSAT also mitigates biosafety risks through the review of "restricted experiments," which under the select agent regulations are experiments that pose heightened biosafety risks. From January 2006 through December 2013, DSAT received 618 requests from 109 entities to perform potentially restricted experiments. Of these requests, 85% were determined not to meet the regulatory definition of a restricted experiment, while 15% of the requests met the definition of a restricted experiment. Of the 91 restricted experiments proposed, DSAT approved 31 (34%) requests because the biosafety conditions proposed were commensurate with the experiments' biosafety risk. All 31 approved restricted experiments were for work with select toxins. DSAT did not approve 60 restricted experiment requests due to potentially serious biosafety risks to public health and safety. All 60 denied restricted experiments proposed inserting drug resistance traits into select agents that could compromise the control of disease. The select agents and toxins associated most frequently with requests that met the regulatory definition of a restricted experiment are Shiga toxin (n = 16), Burkholderia mallei (n = 15), Botulinum neurotoxin (n = 14), and Brucella abortus (n = 14). In general, all restricted experiment decisions are determined on a case-by-case basis. This article describes the trends and characteristics of the data associated with restricted experiment requests among select agents that have an impact on public health and safety (HHS only agents) or both public health and safety and animal health or products (overlap agents). The information presented here, coupled with the information published in the restricted experiment guidance document ( www.selectagents.gov ), is intended to promote awareness among the research community of the type of experiments that meet the regulatory definition of a restricted experiment as well as to provide a greater understanding of the restricted experiment review process.

Predicting the host range of Nystalea ebalea: secondary plant chemistry and host selection by a surrogate biological control agent of Schinus terebinthifolia

USDA-ARS?s Scientific Manuscript database

The safety of weed biological control depends upon the selection and utilization of the target weed by the agent while causing minimal harm to non-target species. Selection of weed species by biological control agents is determined by the presence of behavioral cues, generally host secondary plant c...

A computer program for fast and easy typing of partial endoglucanase gene sequence into phylotypes and sequevars 1&2 (select agents) of Ralstonia solanacearum

USDA-ARS?s Scientific Manuscript database

The phytopathogen Ralstonia solanacearum is a species complex that contains a subset of strains that are quarantined or select agent pathogens. An unidentified R. solanacearum strain is considered a select agent in the US until proven otherwise, which can be done by phylogenetic analysis of a partia...

Co-Selection of Resistance to Antibiotics, Biocides and Heavy Metals, and Its Relevance to Foodborne Pathogens

PubMed Central

Wales, Andrew D.; Davies, Robert H.

2015-01-01

Concerns have been raised in recent years regarding co-selection for antibiotic resistance among bacteria exposed to biocides used as disinfectants, antiseptics and preservatives, and to heavy metals (particularly copper and zinc) used as growth promoters and therapeutic agents for some livestock species. There is indeed experimental and observational evidence that exposure to these non-antibiotic antimicrobial agents can induce or select for bacterial adaptations that result in decreased susceptibility to one or more antibiotics. This may occur via cellular mechanisms that are protective across multiple classes of antimicrobial agents or by selection of genetic determinants for resistance to non-antibiotic agents that are linked to genes for antibiotic resistance. There may also be relevant effects of these antimicrobial agents on bacterial community structure and via non-specific mechanisms such as mobilization of genetic elements or mutagenesis. Notably, some co-selective adaptations have adverse effects on fitness in the absence of a continued selective pressure. The present review examines the evidence for the significance of these phenomena, particularly in respect of bacterial zoonotic agents that commonly occur in livestock and that may be transmitted, directly or via the food chain, to human populations. PMID:27025641

Requirements for facilities transferring or receiving select agents. Final rule.

PubMed

2001-08-31

CDC administers regulations that govern the transfer of certain biological agents and toxins ("select agents"). These regulations require entities that transfer or receive select agents to register with CDC and comply with biosafety standards contained in the Third Edition of the CDC/NIH publication "Biosafety in Microbiological and Biomedical Laboratories ("BMBL")." On October 28,1999, CDC published a Notice of Proposed Rulemaking ("NPRM") seeking both to revise the biosafety standards facilities must follow when handling select agents and to provide new biosecurity standards for such facilities. These new standards are contained in the Fourth Edition of BMBL, which the NPRM proposed to incorporate by reference, thereby replacing the Third Edition. No comments were received in response to this proposal. CDC is therefore amending its regulations to incorporate the Fourth Edition.

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*.

PubMed

Opal, Steven M; Dellinger, R Phillip; Vincent, Jean-Louis; Masur, Henry; Angus, Derek C

2014-07-01

The developmental pipeline for novel therapeutics to treat sepsis has diminished to a trickle compared to previous years of sepsis research. While enormous strides have been made in understanding the basic molecular mechanisms that underlie the pathophysiology of sepsis, a long list of novel agents have now been tested in clinical trials without a single immunomodulating therapy showing consistent benefit. The only antisepsis agent to successfully complete a phase III clinical trial was human recumbent activated protein C. This drug was taken off the market after a follow-up placebo-controlled trial (human recombinant activated Protein C Worldwide Evaluation of Severe Sepsis and septic Shock [PROWESS SHOCK]) failed to replicate the favorable results of the initial registration trial performed ten years earlier. We must critically reevaluate our basic approach to the preclinical and clinical evaluation of new sepsis therapies. We selected the major clinical studies that investigated interventional trials with novel therapies to treat sepsis over the last 30 years. Phase II and phase III trials investigating new treatments for sepsis and editorials and critiques of these studies. Selected manuscripts and clinical study reports were analyzed from sepsis trials. Specific shortcomings and potential pit falls in preclinical evaluation and clinical study design and analysis were reviewed and synthesized. After review and discussion, a series of 12 recommendations were generated with suggestions to guide future studies with new treatments for sepsis. We need to improve our ability to define appropriate molecular targets for preclinical development and develop better methods to determine the clinical value of novel sepsis agents. Clinical trials must have realistic sample sizes and meaningful endpoints. Biomarker-driven studies should be considered to categorize specific "at risk" populations most likely to benefit from a new treatment. Innovations in clinical trial design such as parallel crossover design, alternative endpoints, or adaptive trials should be pursued to improve the outlook for future interventional trials in sepsis.

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N; Hill, D R

1993-04-01

The potential for the hospital library as an accepted patient-focused module is viewed in terms of both the present and the future--or no future--in the introduction to this revised recommended list of 606 books and 143 journals. Predecessors of this list have been intended as selection guides for a small or medium-size library in a hospital or comparable medical facility. Due to rapidly rising prices, the secondary purpose--a basic collection for a consortium of hospital libraries or a network sharing library resources--may eventually become its primary use. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. For the first time, a "minimal core collection" consisting of 85 books has been broken out from the 200 asterisked initial purchase books. To purchase the entire collection of books and to pay for the 1993 subscriptions would require about $87,000; the cost of only the asterisked books and journals totals $34,800. The "minimal core list" of books costs $11,600.

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1993-01-01

The potential for the hospital library as an accepted patient-focused module is viewed in terms of both the present and the future--or no future--in the introduction to this revised recommended list of 606 books and 143 journals. Predecessors of this list have been intended as selection guides for a small or medium-size library in a hospital or comparable medical facility. Due to rapidly rising prices, the secondary purpose--a basic collection for a consortium of hospital libraries or a network sharing library resources--may eventually become its primary use. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. For the first time, a "minimal core collection" consisting of 85 books has been broken out from the 200 asterisked initial purchase books. To purchase the entire collection of books and to pay for the 1993 subscriptions would require about $87,000; the cost of only the asterisked books and journals totals $34,800. The "minimal core list" of books costs $11,600. PMID:8472001

Selecting and Creating a Word List for English Language Teaching

ERIC Educational Resources Information Center

Kwary, Deny A.; Jurianto

2017-01-01

Since the introduction of the General Service List (GSL) in 1953, a number of studies have confirmed the significant role of a word list, particularly GSL, in helping ESL students learn English. Given the recent development in technology, several researchers have created word lists, each of them claims to provide a better coverage of a text and a…

The Preliminary Development of a Vocabulary List for Osaka Jogakuin Junior College's First Year English Program.

ERIC Educational Resources Information Center

Cornwell, Steve; Kakutani, Tomoko

1998-01-01

A project to develop word lists for first-year English as a second language instruction at Osaka Jogakuin Junior College (Japan) is described. The lists were drawn from high-frequency vocabulary lists, with word selection based on course unit themes and rhetorical patterns. These include: introduction/people and places; women's issues;…

Adult Literacy in Developing Countries: A Contemporary Annotated Bibliography.

ERIC Educational Resources Information Center

Puchner, Laurel D.

This bibliography provides a list of 65 selected works on the topic of adult literacy in developing countries. It is a contemporary list, including only works published in the last 15 years. The works are organized into subject categories. Works are listed only once; in cases where a work could be listed under more than one category, it is listed…

Astronomical Resources: A Selected Halley's Comet Reading List.

ERIC Educational Resources Information Center

Fraknoi, Andrew

1985-01-01

Presents annotated lists of: (1) general introductory books about comets and Comet Halley; (2) books about comet history and lore; (3) introductory books for younger children; and (4) books for the serious amateur astronomer. A list of magazine and journal articles is included. (JN)

Advisory List of Computer Courseware.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Educational Media.

Computer courseware appropriate for instruction in grades K-12 is listed in two advisory lists. Entries, selected from materials submitted by producers which received favorable reviews by educators, are arranged in the following categories: arts education, communication skills, mathematics, science, utility (a quiz generator), word processing, and…

Selected list of books and journals in allied health *

PubMed Central

Brandon, Alfred N.; Hill, Dorothy R.

1996-01-01

This list of 410 books and 76 journals is intended as a selection guide to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and described in the AMA's Allied Health and Rehabilitation Professions Education Directory, plus physical therapy, dental allied health, medical secretarial, nutrition, and speech pathology/audiology programs. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (163 books and 31 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1996 subscriptions) would require an expenditure of about $26,740. The cost of only the asterisked items totals $11,160. PMID:16018053

Brandon/Hill selected list of books and journals in allied health.

PubMed Central

Hill, D R; Stickell, H N

1998-01-01

This list of 410 books and 78 journals is intended as a selection guide to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and described in the AMA's Health Professions Education Directory, 1997-1998, plus physical therapist and medical secretary. Some programs do not have their own specific literatures. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (160 books and 31 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1998 subscriptions) would require an expenditure of about $29,180. The cost of only the asterisked items total $11,390. PMID:9803286

Brandon/Hill selected list of books and journals in allied health.

PubMed

Hill, D R; Stickell, H N

1998-10-01

This list of 410 books and 78 journals is intended as a selection guide to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the educational programs listed and described in the AMA's Health Professions Education Directory, 1997-1998, plus physical therapist and medical secretary. Some programs do not have their own specific literatures. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (160 books and 31 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1998 subscriptions) would require an expenditure of about $29,180. The cost of only the asterisked items total $11,390.

Evaluation of Nipah Virus as a Human and Animal Biological Terrorism and Warfare Agent

DTIC Science & Technology

2001-09-01

UNCLASSIFIED Defense Technical Information Center Compilation Part Notice ADP013384 TITLE: Evaluation of Nipah Virus as a Human and Animal Biological...following component part numbers comprise the compilation report: ADP013371 thru ADP013468 UNCLASSIFIED 14. EVALUATION OF NIPAH VIRUS AS A HUMAN AND ANIMAL...of BTWC proposed including Nipah virus in the list of animal pathogens. This paper describes an evaluation of Nipah virus as a biological agent for

A review of the mosquito species (Diptera: Culicidae) of Bangladesh.

PubMed

Irish, Seth R; Al-Amin, Hasan Mohammad; Alam, Mohammad Shafiul; Harbach, Ralph E

2016-10-22

Diseases caused by mosquito-borne pathogens remain an important source of morbidity and mortality in Bangladesh. To better control the vectors that transmit the agents of disease, and hence the diseases they cause, and to appreciate the diversity of the family Culicidae, it is important to have an up-to-date list of the species present in the country. Original records were collected from a literature review to compile a list of the species recorded in Bangladesh. Records for 123 species were collected, although some species had only a single record. This is an increase of ten species over the most recent complete list, compiled nearly 30 years ago. Collection records of three additional species are included here: Anopheles pseudowillmori, Armigeres malayi and Mimomyia luzonensis. While this work constitutes the most complete list of mosquito species collected in Bangladesh, further work is needed to refine this list and understand the distributions of those species within the country. Improved morphological and molecular methods of identification will allow the refinement of this list in years to come.

A Selected and Annotated Resource List of Materials on the Holocaust.

ERIC Educational Resources Information Center

B'nai B'rith, New York, NY. Anti-Defamation League.

This guide for students, teachers, and librarians in secondary schools lists over 200 books and films about the Holocaust. The contents have been selected to help students and others find out what happened during the Holocaust, understand some of the reasons for it, develop a better understanding of the Jewish people, and reflect on their own…

Selected Bibliography and Abstracts of Educational Materials in Pakistan. Volume 6, Number 1, 1972. Period Covered January-March 1972.

ERIC Educational Resources Information Center

Saad, Geti, Comp.

The annotated bibliography lists 111 entries of selected educational materials from Pakistan covering the period from January through March 1972. Entries are listed alphabetically by author under the following thirty-one categories; 1) administrative, organization and financing of education; 2) agricultural education; 3) childhood education; 4)…

An Associative Index Model for the Results List Based on Vannevar Bush's Selection Concept

ERIC Educational Resources Information Center

Cole, Charles; Julien, Charles-Antoine; Leide, John E.

2010-01-01

Introduction: We define the results list problem in information search and suggest the "associative index model", an ad-hoc, user-derived indexing solution based on Vannevar Bush's description of an associative indexing approach for his memex machine. We further define what selection means in indexing terms with reference to Charles…

Selected List of Materials. Sarah K. Davidson Family-Patient Library.

ERIC Educational Resources Information Center

Sanders, Susan, Comp.; Satterwhite, Betty, Comp.

Designed as an aid for those wishing to establish pediatric health education resource centers for use by patients and their families, this bibliography lists selected holdings of the Sarah K. Davidson Family-Patient Library, which is located in the Strong Memorial Hospital of the University of Rochester, New York. It is noted that all…

International Bibliography of Computer-Assisted Terminology.

ERIC Educational Resources Information Center

Krommer-Benz, Magdalena, Comp.

Because of the need for adequate reference tools in the new area of data banks for the field of terminology (there are currently 25 term banks in existence and more are planned), this bibliography lists some 350 references selected from a large number of both primary and secondary sources. It includes some entries selected from a list of…

Drug-induced liver injury due to antimicrobials, central nervous system agents, and nonsteroidal anti-inflammatory drugs.

PubMed

Devarbhavi, Harshad; Andrade, Raúl J

2014-05-01

Antimicrobial agents including antituberculosis (anti-TB) agents are the most common cause of idiosyncratic drug-induced liver injury (DILI) and drug-induced liver failure across the world. Better molecular and genetic biomarkers are acutely needed to help identify those at risk of liver injury particularly for those needing antituberculosis therapy. Some antibiotics such as amoxicillin-clavulanate and isoniazid consistently top the lists of agents in retrospective and prospective DILI databases. Central nervous system agents, particularly antiepileptics, account for the second most common class of agents implicated in DILI registries. Hepatotoxicity from older antiepileptics such as carbamazepine, phenytoin, and phenobarbital are often associated with hypersensitivity features, whereas newer antiepileptic drugs have a more favorable safety profile. Antidepressants and nonsteroidal anti-inflammatory drugs carry very low risk of significant liver injury, but their prolific use make them important causes of DILI. Early diagnosis and withdrawal of the offending agent remain the mainstays of minimizing hepatotoxicity. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Prevalence and pathogens of subclinical mastitis in dairy goats in China.

PubMed

Zhao, Yanqing; Liu, Hui; Zhao, Xuanduo; Gao, Yang; Zhang, Miaotao; Chen, Dekun

2015-02-01

Subclinical mastitis, a costly disease for the dairy industry, is usually caused by intramammary bacterial infection. The aim of this study was to investigate the prevalence of and pathogens involved in subclinical mastitis in dairy goats in China. A total of 683 dairy goats in the main breeding areas of China were selected, and milk samples were collected. Out of these, 313 (45.82 %) goats were detected distinct or strong positive for subclinical mastitis by using California mastitis test. Among these positive goats, 209 milk samples were used to identify the causing agents by a multiplex PCR assay, and results were listed as follows: coagulase-negative staphylococci (59.52 %), Staphylococcus aureus (15.24 %), Escherichia coli (11.43 %), and Streptococcus spp. (10.95 %). In conclusion, subclinical mastitis is a highly prevalent disease in dairy goats in China, and coagulase-negative staphylococci are the predominant pathogens.

Regulation of priority carcinogens and reproductive or developmental toxicants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooper, K.; LaDou, J.; Rosenbaum, J.S.

In California, 370 carcinogens and 112 reproductive/developmental toxicants have been identified as a result of the State's Safe Drinking Water and Toxic Enforcement Act of 1986. They include pesticides, solvents, metals, industrial intermediates, environmental mixtures, and reactive agents. Occupational, environmental, and consumer product exposures that involve these agents are regulated under the Act. At levels of concern, businesses must provide warnings for and limit discharges of those chemicals. The lists of chemicals were compiled following systematic review of published data, including technical reports from the U.S. Public Health Service--National Toxicology Program (NTP), and evaluation of recommendations from authoritative bodies suchmore » as the International Agency for Research on Cancer (IARC) and the U.S. Environmental Protection Agency (USEPA). Given the large number of chemicals that are carcinogens or reproductive/developmental toxicants, regulatory concerns should focus on those that have high potential for human exposure, e.g., widely distributed or easily absorbed solvents, metals, environmental mixtures, or reactive agents. In this paper, we present a list of 33 potential priority carcinogens and reproductive/developmental toxicants, including alcoholic beverages, asbestos, benzene, chlorinated solvents, formaldehyde, glycol ethers, lead, tobacco smoke, and toluene.« less

Regulation of priority carcinogens and reproductive or developmental toxicants.

PubMed

Hooper, K; LaDou, J; Rosenbaum, J S; Book, S A

1992-01-01

In California, 370 carcinogens and 112 reproductive/developmental toxicants have been identified as a result of the State's Safe Drinking Water and Toxic Enforcement Act of 1986. They include pesticides, solvents, metals, industrial intermediates, environmental mixtures, and reactive agents. Occupational, environmental, and consumer product exposures that involve these agents are regulated under the Act. At levels of concern, businesses must provide warnings for and limit discharges of those chemicals. The lists of chemicals were compiled following systematic review of published data, including technical reports from the U.S. Public Health Service--National Toxicology Program (NTP), and evaluation of recommendations from authoritative bodies such as the International Agency for Research on Cancer (IARC) and the U.S. Environmental Protection Agency (USEPA). Given the large number of chemicals that are carcinogens or reproductive/developmental toxicants, regulatory concerns should focus on those that have high potential for human exposure, e.g., widely distributed or easily absorbed solvents, metals, environmental mixtures, or reactive agents. In this paper, we present a list of 33 potential priority carcinogens and reproductive/developmental toxicants, including alcoholic beverages, asbestos, benzene, chlorinated solvents, formaldehyde, glycol ethers, lead, tobacco smoke, and toluene.

21 CFR 514.1 - Applications.

Code of Federal Regulations, 2011 CFR

2011-04-01

... post office address of, and must be countersigned by, an authorized attorney, agent, or official... pharmacologically related drugs. (c) Description of dosage form and quantitative composition. (ii) Scientific... quantitative statement of composition. Reasonable alternatives for any listed component may be specified. (ii...

21 CFR 514.1 - Applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... post office address of, and must be countersigned by, an authorized attorney, agent, or official... pharmacologically related drugs. (c) Description of dosage form and quantitative composition. (ii) Scientific... quantitative statement of composition. Reasonable alternatives for any listed component may be specified. (ii...

21 CFR 514.1 - Applications.

Code of Federal Regulations, 2012 CFR

2012-04-01

... post office address of, and must be countersigned by, an authorized attorney, agent, or official... pharmacologically related drugs. (c) Description of dosage form and quantitative composition. (ii) Scientific... quantitative statement of composition. Reasonable alternatives for any listed component may be specified. (ii...

21 CFR 514.1 - Applications.

Code of Federal Regulations, 2014 CFR

2014-04-01

... post office address of, and must be countersigned by, an authorized attorney, agent, or official... pharmacologically related drugs. (c) Description of dosage form and quantitative composition. (ii) Scientific... quantitative statement of composition. Reasonable alternatives for any listed component may be specified. (ii...

21 CFR 514.1 - Applications.

Code of Federal Regulations, 2013 CFR

2013-04-01

... post office address of, and must be countersigned by, an authorized attorney, agent, or official... pharmacologically related drugs. (c) Description of dosage form and quantitative composition. (ii) Scientific... quantitative statement of composition. Reasonable alternatives for any listed component may be specified. (ii...

MEASURE OCCURRENCE AND EXPOSURE TO CCL-RELATED, EMERGING AND REGULATED WATERBORNE HUMAN PROTOZOA

EPA Science Inventory

Pathogenic waterborne protozoa (Giardia, Cryptosporidium) have been identified as significant etiological agents in the transmission of waterborne disease. Microsporidians, which are on the Agency's Contaminant Candidate List, are obligate intracellular parasites of invertebrate...

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N; Hill, D R

1979-04-01

This revised list of 492 books and 138 journals is intended as a selection guide for small or medium-sized hospital libraries or for the small medical library serving a specified clientele. It can also be used as a core list by small hospital library consortia. Books and journals are categorized by subject, with the books being followed by an author index and the journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by an asterisk. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $22,500. The cost of only the asterisked items, recommended for first purchase, totals approximately $6,100.

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N

1977-04-01

This revised list of 472 books and 138 journals is intended as a selection guide for small or medium-sized hospital libraries or for the small medical library serving a specified clientele. It can also be used as a core list by small hospital library consortia. Books and journals are categorized by subject, with the books being followed by an author index and the journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by an asterisk. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $18,200. The cost of only the asterisked items recommended for first purchase totals approximately $4,500.

Elementary Health: Authorized Resources Annotated List.

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton. Curriculum Standards Branch.

This comprehensive, annotated resource list is designed to assist in selecting resources authorized by the Alberta (Canada) Education Department for the elementary health classroom (Grades 1-6). Within each grade and topic, annotated entries for basic learning resources are listed, followed by support learning resources and authorized teaching…

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N; Hill, D R

1991-04-01

The current financial status of the health care industry is viewed both from its effect on the hospital library collection and the response of the hospital library to the financial crisis. Predecessors of this list have been intended as selection guides for a small or medium-size library in a hospital or comparable medical facility. As the prices of books and journals continue to soar, the secondary purpose as a core collection for a consortium of small hospital libraries or a network sharing library resources may eventually become its primary use. Books (607) and journals (140) are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. To purchase the entire collection of books and to pay for 1991 subscriptions would require about $77,700. The cost of only the asterisked items totals $29,300.

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1991-01-01

The current financial status of the health care industry is viewed both from its effect on the hospital library collection and the response of the hospital library to the financial crisis. Predecessors of this list have been intended as selection guides for a small or medium-size library in a hospital or comparable medical facility. As the prices of books and journals continue to soar, the secondary purpose as a core collection for a consortium of small hospital libraries or a network sharing library resources may eventually become its primary use. Books (607) and journals (140) are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. To purchase the entire collection of books and to pay for 1991 subscriptions would require about $77,700. The cost of only the asterisked items totals $29,300. PMID:2039906

A basic list of recommended books and journals for support of clinical dentistry in a nondental library.

PubMed Central

Johnson, R C; Mason, F O; Sims, R H

1997-01-01

A basic list of 133 book and journal titles in dentistry is presented. The list is intended as a bibliographic selection tool for those libraries and health institutions that support clinical dentistry programs and services in the nondental school environment in the United States and Canada. The book and journal titles were selected by the membership of the Dental Section of the Medical Library Association (MLA). The Dental Section membership represents dental and other health sciences libraries and dental research institutions from the United States and Canada, as well as from other countries. The list was compiled and edited by the Ad Hoc Publications Committee of the Dental Section of MLA. The final list was reviewed and subsequently was approved for publication and distribution by the Dental Section of MLA during the section's 1996 annual meeting in Kansas City, Missouri. PMID:9285122

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

PubMed Central

Moretti, Stefano; van Leeuwen, Danitsja; Gmuender, Hans; Bonassi, Stefano; van Delft, Joost; Kleinjans, Jos; Patrone, Fioravante; Merlo, Domenico Franco

2008-01-01

Background In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. However, the interpretation of each single p-value within complex systems involving several interacting genes is problematic. In parallel, in the last sixty years, game theory has been applied to political and social problems to assess the power of interacting agents in forcing a decision and, more recently, to represent the relevance of genes in response to certain conditions. Results In this paper we introduce a Bootstrap procedure to test the null hypothesis that each gene has the same relevance between two conditions, where the relevance is represented by the Shapley value of a particular coalitional game defined on a microarray data-set. This method, which is called Comparative Analysis of Shapley value (shortly, CASh), is applied to data concerning the gene expression in children differentially exposed to air pollution. The results provided by CASh are compared with the results from a parametric statistical test for testing differential gene expression. Both lists of genes provided by CASh and t-test are informative enough to discriminate exposed subjects on the basis of their gene expression profiles. While many genes are selected in common by CASh and the parametric test, it turns out that the biological interpretation of the differences between these two selections is more interesting, suggesting a different interpretation of the main biological pathways in gene expression regulation for exposed individuals. A simulation study suggests that CASh offers more power than t-test for the detection of differential gene expression variability. Conclusion CASh is successfully applied to gene expression analysis of a data-set where the joint expression behavior of genes may be critical to characterize the expression response to air pollution. We demonstrate a synergistic effect between coalitional games and statistics that resulted in a selection of genes with a potential impact in the regulation of complex pathways. PMID:18764936

Implementation of Multi-Agent Object Attention System Based on Biologically Inspired Attractor Selection

NASA Astrophysics Data System (ADS)

Hashimoto, Ryoji; Matsumura, Tomoya; Nozato, Yoshihiro; Watanabe, Kenji; Onoye, Takao

A multi-agent object attention system is proposed, which is based on biologically inspired attractor selection model. Object attention is facilitated by using a video sequence and a depth map obtained through a compound-eye image sensor TOMBO. Robustness of the multi-agent system over environmental changes is enhanced by utilizing the biological model of adaptive response by attractor selection. To implement the proposed system, an efficient VLSI architecture is employed with reducing enormous computational costs and memory accesses required for depth map processing and multi-agent attractor selection process. According to the FPGA implementation result of the proposed object attention system, which is accomplished by using 7,063 slices, 640×512 pixel input images can be processed in real-time with three agents at a rate of 9fps in 48MHz operation.

TANDEM: A Trust-Based Agent Framework for Networked Decision Making

DTIC Science & Technology

2015-09-10

selective (20–80 %), while the rest are good citizens, trust acts as a method to isolate misbehaving agents. If the majority of the agents have high...competence and low selectivity, then they can use trust to isolate route information around the misbehaving agents, improving Comm and Steps. The impact is...more dramatic when only 20–40 % of the agents are misbehaving . However, using trust results in reduced SA as the information available at the

Peptide-based protein capture agents with high affinity, selectivity, and stability as antibody replacements in biodetection assays

NASA Astrophysics Data System (ADS)

Coppock, Matthew B.; Farrow, Blake; Warner, Candice; Finch, Amethist S.; Lai, Bert; Sarkes, Deborah A.; Heath, James R.; Stratis-Cullum, Dimitra

2014-05-01

Current biodetection assays that employ monoclonal antibodies as primary capture agents exhibit limited fieldability, shelf life, and performance due to batch-to-batch production variability and restricted thermal stability. In order to improve upon the detection of biological threats in fieldable assays and systems for the Army, we are investigating protein catalyzed capture (PCC) agents as drop-in replacements for the existing antibody technology through iterative in situ click chemistry. The PCC agent oligopeptides are developed against known protein epitopes and can be mass produced using robotic methods. In this work, a PCC agent under development will be discussed. The performance, including affinity, selectivity, and stability of the capture agent technology, is analyzed by immunoprecipitation, western blotting, and ELISA experiments. The oligopeptide demonstrates superb selectivity coupled with high affinity through multi-ligand design, and improved thermal, chemical, and biochemical stability due to non-natural amino acid PCC agent design.

8 CFR 207.5 - Waiting lists and priority handling.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REFUGEES § 207.5 Waiting lists and priority handling. Waiting lists are maintained for each designated refugee group of special humanitarian concern. Each applicant whose application is accepted for filing by... filing is the priority date for purposes of case control. Refugees or groups of refugees may be selected...

UNIT, PETROLOGY.

ERIC Educational Resources Information Center

Louisiana Arts and Science Center, Baton Rouge.

THIS TEACHER'S GUIDE FOR A UNIT ON PETROLOGY IS SUITABLE FOR ADAPTATION AT EITHER THE UPPER ELEMENTARY OR THE JUNIOR HIGH SCHOOL LEVELS. THE UNIT BEGINS WITH A STORY THAT INTRODUCES VOLCANIC ACTION AND IGNEOUS ROCK FORMATION. SELECTED CONCEPTS ARE LISTED FOLLOWED BY SUGGESTED ACTIVITIES. A BIBLIOGRAPHY, FILM LIST, VOCABULARY LIST, AND QUESTION AND…

15 CFR 922.10 - General.

Code of Federal Regulations, 2012 CFR

2012-01-01

... site on the SEL, or selection of a site from the SEL as an active candidate for designation as provided... MARINE SANCTUARY PROGRAM REGULATIONS Site Evaluation List (SEL) § 922.10 General. (a) The Site Evaluation List (SEL) was established as a comprehensive list of marine sites with high natural resource values...

15 CFR 922.10 - General.

Code of Federal Regulations, 2013 CFR

2013-01-01

... site on the SEL, or selection of a site from the SEL as an active candidate for designation as provided... MARINE SANCTUARY PROGRAM REGULATIONS Site Evaluation List (SEL) § 922.10 General. (a) The Site Evaluation List (SEL) was established as a comprehensive list of marine sites with high natural resource values...

15 CFR 922.10 - General.

Code of Federal Regulations, 2014 CFR

2014-01-01

... site on the SEL, or selection of a site from the SEL as an active candidate for designation as provided... MARINE SANCTUARY PROGRAM REGULATIONS Site Evaluation List (SEL) § 922.10 General. (a) The Site Evaluation List (SEL) was established as a comprehensive list of marine sites with high natural resource values...

Advisory List of Instructional Media for Mathematics. 1979-80 School Year.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Educational Media.

This annotated bibliography from the Materials Review and Evaluation Services lists reviewed and evaluated instructional media appropriate for school media centers in the area of mathematics. Entries included on the list were selected from those materials submitted by publishers which received favorable reviews by educators. Materials are arranged…

RELATIVE RATE CONSTANTS OF CONTAMINANT CANDIDATE LIST PESTICIDES WITH HYDROXYL RADICALS

EPA Science Inventory

The objective of this study was to establish the rate constants for the reactions of selected pesticides listed on the US EPA Contaminant Candidate List, with UV and hydroxyl radicals (·OH). Batch experiments were conducted in phosphate buffered solution at pH 7. All pestici...

A Feature and Algorithm Selection Method for Improving the Prediction of Protein Structural Class.

PubMed

Ni, Qianwu; Chen, Lei

2017-01-01

Correct prediction of protein structural class is beneficial to investigation on protein functions, regulations and interactions. In recent years, several computational methods have been proposed in this regard. However, based on various features, it is still a great challenge to select proper classification algorithm and extract essential features to participate in classification. In this study, a feature and algorithm selection method was presented for improving the accuracy of protein structural class prediction. The amino acid compositions and physiochemical features were adopted to represent features and thirty-eight machine learning algorithms collected in Weka were employed. All features were first analyzed by a feature selection method, minimum redundancy maximum relevance (mRMR), producing a feature list. Then, several feature sets were constructed by adding features in the list one by one. For each feature set, thirtyeight algorithms were executed on a dataset, in which proteins were represented by features in the set. The predicted classes yielded by these algorithms and true class of each protein were collected to construct a dataset, which were analyzed by mRMR method, yielding an algorithm list. From the algorithm list, the algorithm was taken one by one to build an ensemble prediction model. Finally, we selected the ensemble prediction model with the best performance as the optimal ensemble prediction model. Experimental results indicate that the constructed model is much superior to models using single algorithm and other models that only adopt feature selection procedure or algorithm selection procedure. The feature selection procedure or algorithm selection procedure are really helpful for building an ensemble prediction model that can yield a better performance. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

A comparison of selection at list time and time-stratified sampling for estimating suspended sediment loads

Treesearch

Robert B. Thomas; Jack Lewis

1993-01-01

Time-stratified sampling of sediment for estimating suspended load is introduced and compared to selection at list time (SALT) sampling. Both methods provide unbiased estimates of load and variance. The magnitude of the variance of the two methods is compared using five storm populations of suspended sediment flux derived from turbidity data. Under like conditions,...

Competency Index for Building Trades Programs in Missouri. A Crosswalk of Selected Instructional Materials against Missouri's Competency Profile.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This index was developed to help building trades instructors in Missouri use existing instructional materials and keep track of student progress on the VAMS system. The list was compiled by a committee of instructors who selected appropriate references and identified areas that pertained to Missouri competencies. The index lists competencies in…

Mini-Tn7 Insertion in Bacteria With Multiple glmS-Linked attTn7 Sites: Example Burkholderia Mallei ATCC 23344

DTIC Science & Technology

2006-06-27

INTRODUCTION Burkholderia mallei is the etiological agent of glanders and a highly evolved obligate zoonotic mammalian pathogen that naturally affects horses...mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei ATCC 23344 Kyoung-Hee Choi1, David DeShazer2... glanders is a rare disease, B. mallei has received renewed attention because of its listing as a category B agent by the Centers for Disease Control

Department of Defense Federal Hazard Communication Training Program, Trainer’s Guide

DTIC Science & Technology

1988-04-01

Information Tell trainees: Marilyn works as a supervisor in a plant that uses ammonium nitrate to make gun powder and blasting agents. List choices and ask...Continued Marilyn works as a supervisor in a plant that uses ammonium nitrate to make gun powder and blasting agents. 3) What physical hazard is...friend worked twenty years ago for 6 months in a plant where benzidine was used to make dyes. This year, both have developed the same type of bladder

Editorial: Reviewer Selection Process and New Areas of Expertise in GEMS

NASA Technical Reports Server (NTRS)

Liemohn, Michael W.; Balikhin, Michael; Kepko, Larry; Rodger, Alan; Wang, Yuming

2016-01-01

One method of selecting potential reviewers for papers submitted to the Journal of Geophysical Research Space Physics is to filter the user database within the Geophysical Electronic Manuscript System (GEMS) by areas of expertise. The list of these areas in GEMS can be self selected by users in their profile settings. The Editors have added 18 new entries to this list, an increase of 33 more than the previous 55 entries. All space physicists are strongly encouraged to update their profile settings in GEMS, especially their areas of expertise selections, and details of how to do this are provided.

Editorial: Reviewer selection process and new areas of expertise in GEMS

NASA Astrophysics Data System (ADS)

Liemohn, Michael W.; Balikhin, Michael; Kepko, Larry; Rodger, Alan; Wang, Yuming

2016-06-01

One method of selecting potential reviewers for papers submitted to the Journal of Geophysical Research Space Physics is to filter the user database within the Geophysical Electronic Manuscript System (GEMS) by areas of expertise. The list of these areas in GEMS can be self selected by users in their profile settings. The Editors have added 18 new entries to this list, an increase of 33% more than the previous 55 entries. All space physicists are strongly encouraged to update their profile settings in GEMS, especially their areas of expertise selections, and details of how to do this are provided.

Hypoxia-inducible factor stabilizers and other small-molecule erythropoiesis-stimulating agents in current and preventive doping analysis.

PubMed

Beuck, Simon; Schänzer, Wilhelm; Thevis, Mario

2012-11-01

Increasing the blood's capacity for oxygen transport by erythropoiesis-stimulating agents (ESAs) constitutes a prohibited procedure of performance enhancement according to the World Anti-Doping Agency (WADA). The advent of orally bio-available small-molecule ESAs such as hypoxia-inducible factor (HIF) stabilizers in the development of novel anti-anaemia therapies expands the list of potential ESA doping techniques. Here, the erythropoiesis-stimulating properties and doping relevance of experimental HIF-stabilizers, such as cobaltous chloride, 3,4-dihydroxybenzoic acid or GSK360A, amongst others, are discussed. The stage of clinical trials is reviewed for the anti-anaemia drug candidates FG-2216, FG-4592, GSK1278863, AKB-6548, and BAY85-3934. Currently available methods and strategies for the determination of selected HIF stabilizers in sports drug testing are based on liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS). For the support of further analytical assay development, patents claiming distinct compounds for the use in HIF-mediated therapies are evaluated and exemplary molecular structures of HIF stabilizers presented. Moreover, data concerning the erythropoiesis-enhancing effects of the GATA inhibitors K7174 and K11706 as well as the lipidic small-molecule ESA PBI-1402 are elucidated the context of doping analysis. Copyright © 2012 John Wiley & Sons, Ltd.

The Effect of the Length of To-Be-Remembered Lists and Intervening Lists on Free Recall: A Reexamination Using Overt Rehearsal

ERIC Educational Resources Information Center

Ward, Geoff; Tan, Lydia

2004-01-01

In 3 experiments, the authors investigated the effects of to-be-remembered (TBR) and intervening list length on free recall to determine whether selective rehearsal could explain the previous finding that recall was affected only by TBR list length. In Experiments 1 (covert rehearsal) and 2 (overt rehearsal), participants saw 5- and 20-word lists…

Review of Restricted Experiment Requests, Division of Select Agents and Toxins, Centers for Disease Control and Prevention, 2006-2013

PubMed Central

Smith, Jacinta; Weyant, Robbin

2015-01-01

The Centers for Disease Control and Prevention (CDC) Division of Select Agents and Toxins (DSAT) regulates laboratories that possess, use, or transfer select agents and toxins in the United States. DSAT also mitigates biosafety risks through the review of “restricted experiments,” which under the select agent regulations are experiments that pose heightened biosafety risks. From January 2006 through December 2013, DSAT received 618 requests from 109 entities to perform potentially restricted experiments. Of these requests, 85% were determined not to meet the regulatory definition of a restricted experiment, while 15% of the requests met the definition of a restricted experiment. Of the 91 restricted experiments proposed, DSAT approved 31 (34%) requests because the biosafety conditions proposed were commensurate with the experiments' biosafety risk. All 31 approved restricted experiments were for work with select toxins. DSAT did not approve 60 restricted experiment requests due to potentially serious biosafety risks to public health and safety. All 60 denied restricted experiments proposed inserting drug resistance traits into select agents that could compromise the control of disease. The select agents and toxins associated most frequently with requests that met the regulatory definition of a restricted experiment are Shiga toxin (n = 16), Burkholderia mallei (n = 15), Botulinum neurotoxin (n = 14), and Brucella abortus (n = 14). In general, all restricted experiment decisions are determined on a case-by-case basis. This article describes the trends and characteristics of the data associated with restricted experiment requests among select agents that have an impact on public health and safety (HHS only agents) or both public health and safety and animal health or products (overlap agents). The information presented here, coupled with the information published in the restricted experiment guidance document (www.selectagents.gov), is intended to promote awareness among the research community of the type of experiments that meet the regulatory definition of a restricted experiment as well as to provide a greater understanding of the restricted experiment review process. PMID:26347984

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N

1977-01-01

This revised list of 472 books and 138 journals is intended as a selection guide for small or medium-sized hospital libraries or for the small medical library serving a specified clientele. It can also be used as a core list by small hospital library consortia. Books and journals are categorized by subject, with the books being followed by an author index and the journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by an asterisk. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $18,200. The cost of only the asterisked items recommended for first purchase totals approximately $4,500. PMID:321057

Selected list of books and journals for the small medical library.

PubMed Central

Brandon, A N; Hill, D R

1979-01-01

This revised list of 492 books and 138 journals is intended as a selection guide for small or medium-sized hospital libraries or for the small medical library serving a specified clientele. It can also be used as a core list by small hospital library consortia. Books and journals are categorized by subject, with the books being followed by an author index and the journals by an alphabetical title listing. Items suggested for initial purchase by smaller libraries are indicated by an asterisk. To purchase the entire collection of books and to pay for annual subscriptions to all the journals would require an expenditure of about $22,500. The cost of only the asterisked items, recommended for first purchase, totals approximately $6,100. PMID:380695

Design Principles of Nanoparticles as Contrast Agents for Magnetic Resonance Imaging

NASA Astrophysics Data System (ADS)

Shan, Liang; Gu, Xinbin; Wang, Paul

2013-09-01

Molecular imaging is an emerging field that introduces molecular agents into traditional imaging techniques, enabling visualization, characterization and measurement of biological processes at the molecular and cellular levels in humans and other living systems. The promise of molecular imaging lies in its potential for selective potency by targeting biomarkers or molecular targets and the imaging agents serve as reporters for the selectivity of targeting. Development of an efficient molecular imaging agent depends on well-controlled high-quality experiment design involving target selection, agent synthesis, in vitro characterization, and in vivo animal characterization before it is applied in humans. According to the analysis from the Molecular Imaging and Contrast Agent Database (MICAD, ), more than 6000 molecular imaging agents with sufficient preclinical evaluation have been reported to date in the literature and this number increases by 250-300 novel agents each year. The majority of these agents are radionuclides, which are developed for positron emission tomography (PET) and single photon emission computed tomography (SPECT). Contrast agents for magnetic resonance imaging (MRI) account for only a small part. This is largely due to the fact that MRI is currently not a fully quantitative imaging technique and is less sensitive than PET and SPECT. However, because of the superior ability to simultaneously extract molecular and anatomic information, molecular MRI is attracting significant interest and various targeted nanoparticle contrast agents have been synthesized for MRI. The first and one of the most critical steps in developing a targeted nanoparticle contrast agent is target selection, which plays the central role and forms the basis for success of molecular imaging. This chapter discusses the design principles of targeted contrast agents in the emerging frontiers of molecular MRI.

MannDB: A microbial annotation database for protein characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, C; Lam, M; Smith, J

2006-05-19

MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the development of reagents for pathogen or protein toxin detection. Because a large number of open-source tools were needed, it was necessary to produce a software system to scale the computations for whole-proteome analysis. Thus, we built a fully automated system for executing software tools and for storage, integration, and display of automated protein sequence analysis and annotation data. MannDB is a relational database that organizes data resulting from fully automated, high-throughput protein-sequence analyses using open-sourcemore » tools. Types of analyses provided include predictions of cleavage, chemical properties, classification, features, functional assignment, post-translational modifications, motifs, antigenicity, and secondary structure. Proteomes (lists of hypothetical and known proteins) are downloaded and parsed from Genbank and then inserted into MannDB, and annotations from SwissProt are downloaded when identifiers are found in the Genbank entry or when identical sequences are identified. Currently 36 open-source tools are run against MannDB protein sequences either on local systems or by means of batch submission to external servers. In addition, BLAST against protein entries in MvirDB, our database of microbial virulence factors, is performed. A web client browser enables viewing of computational results and downloaded annotations, and a query tool enables structured and free-text search capabilities. When available, links to external databases, including MvirDB, are provided. MannDB contains whole-proteome analyses for at least one representative organism from each category of biological threat organism listed by APHIS, CDC, HHS, NIAID, USDA, USFDA, and WHO. MannDB comprises a large number of genomes and comprehensive protein sequence analyses representing organisms listed as high-priority agents on the websites of several governmental organizations concerned with bio-terrorism. MannDB provides the user with a BLAST interface for comparison of native and non-native sequences and a query tool for conveniently selecting proteins of interest. In addition, the user has access to a web-based browser that compiles comprehensive and extensive reports.« less

Adaptive consensus of scale-free multi-agent system by randomly selecting links

NASA Astrophysics Data System (ADS)

Mou, Jinping; Ge, Huafeng

2016-06-01

This paper investigates an adaptive consensus problem for distributed scale-free multi-agent systems (SFMASs) by randomly selecting links, where the degree of each node follows a power-law distribution. The randomly selecting links are based on the assumption that every agent decides to select links among its neighbours according to the received data with a certain probability. Accordingly, a novel consensus protocol with the range of the received data is developed, and each node updates its state according to the protocol. By the iterative method and Cauchy inequality, the theoretical analysis shows that all errors among agents converge to zero, and in the meanwhile, several criteria of consensus are obtained. One numerical example shows the reliability of the proposed methods.

Websites for Primary Sources and Civics Education

ERIC Educational Resources Information Center

Rulli, Daniel

2005-01-01

This article features a list of websites for primary sources and civics education. The World Wide Web has become an excellent source for facsimiles, images, and transcriptions of primary sources. As it would be impossible to provide a comprehensive list of all the sites, this annotated list highlights selective sites that provide access to…

77 FR 42778 - Product List Change

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... proposed new product under 39 U.S.C. 3632(b)(3) and 39 CFR 3015.5. Id. Attachment B. The instant contract... POSTAL REGULATORY COMMISSION [Docket Nos. MC2012-34 and CP2012-42; Order No. 1405] Product List... recently-filed Postal Service request to add Parcel Select Contract 5 to the competitive product list. This...

77 FR 42779 - Product List Change

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... proposed new product under 39 U.S.C. 3632(b)(3) and 39 CFR 3015.5. Id. Attachment B. The instant contract... POSTAL REGULATORY COMMISSION [Docket Nos. MC2012-33 and CP2012-41; Order No. 1404] Product List... recently-filed Postal Service request to add Parcel Select Contract 4 to the competitive product list. This...

Radar Image Processing for the AFIT Anechoic Chamber

DTIC Science & Technology

1990-12-01

analyzer is set up for data collection using the frequency list mode option. The frequency list mode, a variation of the step sweep mode, synthesizes each of...enhanced since the frequencies are precisely repeated. The frequency list option allows the operator to select any number of data samples from 1 to 401. This

77 FR 42052 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; NYSE Arca, Inc.; Order Instituting...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... proposed MQP would be a program designed to promote market quality in certain securities listed on NASDAQ... contain the specific quantitative listing requirements for listing on the Global Select, Global Market... pilot (for comparative purposes), volume metrics, NBBO bid/ask spread differentials, LMM participation...

Microbial Resistance to Triclosan: A Case Study in Natural Selection

ERIC Educational Resources Information Center

Serafini, Amanda; Matthews, Dorothy M.

2009-01-01

Natural selection is the mechanism of evolution caused by the environmental selection of organisms most fit to reproduce, sometimes explained as "survival of the fittest." An example of evolution by natural selection is the development of bacteria that are resistant to antimicrobial agents as a result of exposure to these agents. Triclosan, which…

Milagro Observations of Potential TeV Emitters

NASA Technical Reports Server (NTRS)

Abdo, A. A.; Abeysekara, A. U.; Allen, B. T.; Aune, T.; Barber, A. S.; Berley, D.; Braun, J.; Chen, C.; Christopher, G. E.; DeYoung, T.;

MATline: a job-exposure matrix for carcinogenic chemicals.

PubMed

Gilardi, Luisella; Falcone, Umberto; Santoro, Silvano; Coffano, Elena

2008-01-01

MATline is a tool that can be used to predict which industrial processes can be expected to involve the use of a substance that is considered carcinogenic as documented in the literature. The database includes agents carrying risk phrases R45, R49 and R40 according to the method of classification adopted by the EU and/or agents in categories 1, 2A and 2B as classified by the International Agency for Research on Cancer (IARC). Each agent is associated with a list of industrial processes coded according to the tariff headings used by the National Institute of Insurance against Occupational Injuries and Diseases (Istituto Nazionale per l'Assicurazione contro gli Infortuni sul Lavoro, INAIL). The main sources of information are the IARC Monographs and databases available through the National Library of Medicine's TOXNET portal. The matrix currently includes 600 carcinogenic agents, 23 classes of agents and some 7000 links between agents and industrial processes. MATline can be viewed on the www.dors.it website.

21 CFR 1306.21 - Requirement of prescription.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Substances Listed in Schedules III, IV, and V § 1306.21 Requirement of prescription. (a) A pharmacist may... individual practitioner and promptly reduced to writing by the pharmacist containing all information required... agent to the institutional practitioner-pharmacist, an electronic prescription that meets the...

21 CFR 1306.21 - Requirement of prescription.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Substances Listed in Schedules III, IV, and V § 1306.21 Requirement of prescription. (a) A pharmacist may... individual practitioner and promptly reduced to writing by the pharmacist containing all information required... agent to the institutional practitioner-pharmacist, an electronic prescription that meets the...

21 CFR 1306.21 - Requirement of prescription.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Substances Listed in Schedules III, IV, and V § 1306.21 Requirement of prescription. (a) A pharmacist may... individual practitioner and promptly reduced to writing by the pharmacist containing all information required... agent to the institutional practitioner-pharmacist, an electronic prescription that meets the...

21 CFR 1306.21 - Requirement of prescription.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Substances Listed in Schedules III, IV, and V § 1306.21 Requirement of prescription. (a) A pharmacist may... individual practitioner and promptly reduced to writing by the pharmacist containing all information required... agent to the institutional practitioner-pharmacist, an electronic prescription that meets the...

The View From the Purchasing Agent's Chair

ERIC Educational Resources Information Center

Walters, Richard P.

1974-01-01

Presents ways to improve communication with the purchasing office: summarizing procedures of purchasing in a brochure for the whole university; update bidder lists; buy from sources as close to the university as possible; and look for substitute products at all times. (Author/PG)

Differential diagnosis of delayed awakening from general anesthesia: a review.

PubMed

Frost, Elizabeth A M

2014-10-01

With the general use of fast acting anesthetic agents, patients usually awaken quickly in the post operative period. However, sometimes recovery is protracted and the list of possible causes in long. Accurate diagnosis is key to institution of appropriate therapy.

Selected Bibliography and Abstracts of Educational Materials in Pakistan. Volume 6, Number 4, 1972. Period Covered October-December 1972.

ERIC Educational Resources Information Center

Saad, Geti, Comp.

This annotated bibliography lists 104 entries of selected educational materials in Pakistan covering the period from October to December 1972. The materials are organized into 30 topical categories as listed for related document ED 074 847. A new section is added on nationalization of education. The materials are drawn from a variety of Pakistani…

Selected Bibliography and Abstracts of Educational Materials in Pakistan. Volume 6, Number 3, 1972. Period Covered July-September 1972.

ERIC Educational Resources Information Center

Saad, Geti, Comp.

This annotated bibliography lists 102 entries of selected educational materials in Pakistan covering the period from July to September 1972. The materials are organized into 24 categories as listed for related document ED 074 847. A new section is added on nationalization of education. The materials are drawn from a variety of Pakistani journals,…

Business Education Index, 1999. Index of Business Education Articles and Research Studies Compiled from a Selected List of Periodicals Published During the Year 1999. Volume 60.

ERIC Educational Resources Information Center

Noll, Cheryl L., Ed.; Graves, Pat R., Ed.

This publication comprises an index of business education articles and research studies compiled from a selected list of business education periodicals and those related to business education published during 1999. Priority is given to journals essential to research and teaching over the broad business education spectrum. Subject entries (pages…

Desirable Traits of a Good Biocontrol Agent against Verticillium Wilt.

PubMed

Deketelaere, Silke; Tyvaert, Lien; França, Soraya C; Höfte, Monica

2017-01-01

The soil-borne fungus Verticillium causes serious vascular disease in a wide variety of annual crops and woody perennials. Verticillium wilt is notoriously difficult to control by conventional methods, so there is great potential for biocontrol to manage this disease. In this study we aimed to review the research about Verticillium biocontrol to get a better understanding of characteristics that are desirable in a biocontrol agent (BCA) against Verticillium wilt. We only considered studies in which the BCAs were tested on plants. Most biocontrol studies were focused on plants of the Solanaceae, Malvaceae , and Brassicaceae and within these families eggplant, cotton, and oilseed rape were the most studied crops. The list of bacterial BCAs with potential against Verticillium was dominated by endophytic Bacillus and Pseudomonas isolates, while non-pathogenic xylem-colonizing Verticillium and Fusarium isolates topped the fungal list. Predominant modes of action involved in biocontrol were inhibition of primary inoculum germination, plant growth promotion, competition and induced resistance. Many BCAs showed in vitro antibiosis and mycoparasitism but these traits were not correlated with activity in vivo and there is no evidence that they play a role in planta . Good BCAs were obtained from soils suppressive to Verticillium wilt, disease suppressive composts, and healthy plants in infested fields. Desirable characteristics in a BCA against Verticillium are the ability to (1) affect the survival or germination of microsclerotia, (2) colonize the xylem and/or cortex and compete with the pathogen for nutrients and/or space, (3) induce resistance responses in the plant and/or (4) promote plant growth. Potential BCAs should be screened in conditions that resemble the field situation to increase the chance of successful use in practice. Furthermore, issues such as large scale production, formulation, preservation conditions, shelf life, and application methods should be considered early in the process of selecting BCAs against Verticillium .

Desirable Traits of a Good Biocontrol Agent against Verticillium Wilt

PubMed Central

Deketelaere, Silke; Tyvaert, Lien; França, Soraya C.; Höfte, Monica

2017-01-01

The soil-borne fungus Verticillium causes serious vascular disease in a wide variety of annual crops and woody perennials. Verticillium wilt is notoriously difficult to control by conventional methods, so there is great potential for biocontrol to manage this disease. In this study we aimed to review the research about Verticillium biocontrol to get a better understanding of characteristics that are desirable in a biocontrol agent (BCA) against Verticillium wilt. We only considered studies in which the BCAs were tested on plants. Most biocontrol studies were focused on plants of the Solanaceae, Malvaceae, and Brassicaceae and within these families eggplant, cotton, and oilseed rape were the most studied crops. The list of bacterial BCAs with potential against Verticillium was dominated by endophytic Bacillus and Pseudomonas isolates, while non-pathogenic xylem-colonizing Verticillium and Fusarium isolates topped the fungal list. Predominant modes of action involved in biocontrol were inhibition of primary inoculum germination, plant growth promotion, competition and induced resistance. Many BCAs showed in vitro antibiosis and mycoparasitism but these traits were not correlated with activity in vivo and there is no evidence that they play a role in planta. Good BCAs were obtained from soils suppressive to Verticillium wilt, disease suppressive composts, and healthy plants in infested fields. Desirable characteristics in a BCA against Verticillium are the ability to (1) affect the survival or germination of microsclerotia, (2) colonize the xylem and/or cortex and compete with the pathogen for nutrients and/or space, (3) induce resistance responses in the plant and/or (4) promote plant growth. Potential BCAs should be screened in conditions that resemble the field situation to increase the chance of successful use in practice. Furthermore, issues such as large scale production, formulation, preservation conditions, shelf life, and application methods should be considered early in the process of selecting BCAs against Verticillium. PMID:28729855

Searching fee and non-fee toxicology information resources: an overview of selected databases.

PubMed

Wright, L L

2001-01-12

Toxicology profiles organize information by broad subjects, the first of which affirms identity of the agent studied. Studies here show two non-fee databases (ChemFinder and ChemIDplus) verify the identity of compounds with high efficiency (63% and 73% respectively) with the fee-based Chemical Abstracts Registry file serving well to fill data gaps (100%). Continued searching proceeds using knowledge of structure, scope and content to select databases. Valuable sources for information are factual databases that collect data and facts in special subject areas organized in formats available for analysis or use. Some sources representative of factual files are RTECS, CCRIS, HSDB, GENE-TOX and IRIS. Numerous factual databases offer a wealth of reliable information; however, exhaustive searches probe information published in journal articles and/or technical reports with records residing in bibliographic databases such as BIOSIS, EMBASE, MEDLINE, TOXLINE and Web of Science. Listed with descriptions are numerous factual and bibliographic databases supplied by 11 producers. Given the multitude of options and resources, it is often necessary to seek service desk assistance. Questions were posed by telephone and e-mail to service desks at DIALOG, ISI, MEDLARS, Micromedex and STN International. Results of the survey are reported.

Fluorination utilizing thermodynamically unstable fluorides and fluoride salts thereof

DOEpatents

Bartlett, Neil; Whalen, J. Marc; Chacon, Lisa

2000-12-12

A method for fluorinating a carbon compound or cationic carbon compound utilizes a fluorination agent selected from thermodynamically unstable nickel fluorides and salts thereof in liquid anhydrous hydrogen fluoride. The desired carbon compound or cationic organic compound to undergo fluorination is selected and reacted with the fluorination agent by contacting the selected organic or cationic organic compound and the chosen fluorination agent in a reaction vessel for a desired reaction time period at room temperature or less.

Drug dependence: its significance and characteristics

PubMed Central

Eddy, Nathan B.; Halbach, H.; Isbell, Harris; Seevers, Maurice H.

1965-01-01

It has become impossible in practice, and is scientifically unsound, to maintain a single definition for all forms of drug addiction and/or habituation. A feature common to these conditions as well as to drug abuse in general is dependence, psychic or physical or both, of the individual on a chemical agent. Therefore, better understanding should be attained by substitution of the term drug dependence of this or that type, according to the agent or class of agents involved, in discussions of these conditions, especially inter-disciplinary. Short descriptions, followed by concise listings of their characteristics, are formulated for the various types of dependence on at present widely abused major groups of substances. PMID:5294186

The effect of the length of to-be-remembered lists and intervening lists on free recall: a reexamination using overt rehearsal.

PubMed

Ward, Geoff; Tan, Lydia

2004-11-01

In 3 experiments, the authors investigated the effects of to-be-remembered (TBR) and intervening list length on free recall to determine whether selective rehearsal could explain the previous finding that recall was affected only by TBR list length. In Experiments 1 (covert rehearsal) and 2 (overt rehearsal), participants saw 5- and 20-word lists and had to recall the list prior to that last presented list. In Experiment 3, either 1 or 2 lists were presented, and recall of TBR list was postcued. Recall proportion decreased with increased TBR list length. Moreover, the authors found extended recency effects when recall was replotted by when words were last rehearsed (Experiments 2 and 3) and an effect of intervening list length when rehearsal was reduced (Experiment 3). ((c) 2004 APA, all rights reserved).

Selected List of Books and Journals for the Small Medical Library *

PubMed Central

Brandon, Alfred N.

1973-01-01

This updated list of 410 books and 136 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk. To purchase the entire collection of books and to pay for the annual subscription costs of all the journals would require an expenditure of about $12,000. To acquire only those items suggested for first purchase, approximately $3,250 would be needed. PMID:4702804

Selected list of books and journals for the small medical library.

PubMed

Brandon, A N

1973-04-01

This updated list of 410 books and 136 journals is intended as a selection aid for the small library of a hospital, medical society, clinic, or similar organization. Books and journals are arranged by subject, with the books followed by an author index, and the journals by an alphabetical title listing. Items suggested for first purchase by smaller libraries are noted by an asterisk. To purchase the entire collection of books and to pay for the annual subscription costs of all the journals would require an expenditure of about $12,000. To acquire only those items suggested for first purchase, approximately $3,250 would be needed.

Selected list of books and journals in the allied health sciences.

PubMed Central

Brandon, A N; Hill, D R

1986-01-01

This list of 450 books and 69 journals is intended as a selection guide to be used in a library supporting allied health educational programs and/or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused mainly on the twenty-three educational programs accredited by the Committee on Allied Health Education and Accreditation of the American Medical Association, plus physical therapy, dental allied health, and medical secretarial programs. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (157 books and 27 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1986 subscriptions) would require an expenditure of about $16,700. The cost of only the asterisked items totals $6,700. PMID:3535953

Selected list of books and journals in allied health sciences.

PubMed Central

Brandon, A N; Hill, D R

1990-01-01

This list of 453 books and 74 journals is intended as a selection guide to be used in a library supporting allied health educational programs or allied health personnel in either an academic or health care setting. Because of the impossibility of covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the twenty-six educational programs accredited by the Committee on Allied Health Education and Accreditation of the American Medical Association, plus physical therapy, dental allied health, medical secretarial, and nutrition programs. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (179 books and 29 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1990 subscriptions) would require an expenditure of about $21,650. The cost of only the asterisked items totals $9,250. PMID:2393755

Selected list of books and journals in allied health sciences.

PubMed Central

Brandon, A N; Hill, D R

1988-01-01

This list of 435 books and 76 journals is intended as a selection guide to be used in a library supporting allied health educational programs and/or health personnel in either an academic or health care setting. Because of the impossibility pf covering the large number and wide variety of allied health professions and occupations, the recommended publications are focused primarily on the twenty-six educational programs accredited by the Committee on Allied Health Education and Accreditation of the American Medical Association, plus physical therapy, dental allied health, nutrition, and medical secretarial programs. Books and journals are categorized by subject; the book list is followed by an author/editor index, and the subject list of journals by an alphabetical title listing. Items suggested for initial purchase (176 books and 29 journals) are indicated by asterisks. To purchase the entire collection of books and journals (1988 subscriptions) would require an expenditure of about $19,000. The cost of only the asterisked items totals $7,900. PMID:3066428

Biological Select Agents and Toxins: Risk-Based Assessment Management and Oversight.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burnett, LouAnn Crawford; Brodsky, Benjamin H.

Sandia National Laboratories' International Biological and Chemical Threat Reduction (SNL/IBCTR) conducted, on behalf of the Federal Select Agent Program (FSAP), a review of risk assessment in modern select agent laboratories. This review and analysis consisted of literature review, interviews of FSAP staff, entities regulated by FSAP, and deliberations of an expert panel. Additionally, SNL/IBCTR reviewed oversight mechanisms used by industries, US agencies, and other countries for high-consequence risks (e.g, nuclear, chemical, or biological materials, aviation, off-shore drilling, etc.) to determine if alternate oversight mechanisms existed that might be applicable to FSAP oversight of biological select agents and toxins. This reportmore » contains five findings, based on these reviews and analyses, with recommendations and suggested actions for FSAP to consider.« less

Pollinator-mediated natural selection in Penstemon digitalis.

PubMed

Parachnowitsch, Amy; Kessler, André

2010-12-01

Measuring the agents of natural selection is important because it allows us to understand not only which traits are expected to evolve but also why they will evolve. Natural selection by pollinators on floral traits is often assumed because in outcrossing animal-pollinated plants flowers are generally thought to function as advertisements of rewards directed at pollinators. We tested the role of bee pollinators in selection on Penstemon digitalis and found that pollinators were driving selection for larger and more flowers. However, what makes our publication unique is the additional information we gained from reviewing the few other studies that also directly tested whether pollinators were agents of selection on floral traits. As we would expect if pollinators are important agents of selection, selection on floral traits was significantly stronger when pollinators were present than when they were experimentally removed. Taken together, these results suggest that pollinators can be important drivers of selection in contemporary populations.

40 CFR 62.14490 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... occur during combustion. Biologicals means preparations made from living organisms and their products... biologicals that is listed in paragraphs (1) through (7) of this definition. The definition of medical... § 261.4(a)(1) of this chapter. (1) Cultures and stocks of infectious agents and associated biologicals...

40 CFR 62.14490 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... occur during combustion. Biologicals means preparations made from living organisms and their products... biologicals that is listed in paragraphs (1) through (7) of this definition. The definition of medical... § 261.4(a)(1) of this chapter. (1) Cultures and stocks of infectious agents and associated biologicals...

5 CFR Appendix B to Part 581 - List of Agents Designated To Facilitate the Service of Legal Process on Federal Employees

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Post Office Box 2905, Fort Worth, TX 76113, (817) 885-5471 Great Plains (Kansas, Missouri, Iowa, and..., (410) 642-2411, ext. 5193 Baltimore Rehabilitation, Research and Development Center, Send to: Human...

5 CFR Appendix B to Part 581 - List of Agents Designated To Facilitate the Service of Legal Process on Federal Employees

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Post Office Box 2905, Fort Worth, TX 76113, (817) 885-5471 Great Plains (Kansas, Missouri, Iowa, and..., (410) 642-2411, ext. 5193 Baltimore Rehabilitation, Research and Development Center, Send to: Human...

5 CFR Appendix B to Part 581 - List of Agents Designated To Facilitate the Service of Legal Process on Federal Employees

Code of Federal Regulations, 2010 CFR

2010-01-01

..., Post Office Box 2905, Fort Worth, TX 76113, (817) 885-5471 Great Plains (Kansas, Missouri, Iowa, and..., (410) 642-2411, ext. 5193 Baltimore Rehabilitation, Research and Development Center, Send to: Human...

5 CFR Appendix B to Part 581 - List of Agents Designated To Facilitate the Service of Legal Process on Federal Employees

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Post Office Box 2905, Fort Worth, TX 76113, (817) 885-5471 Great Plains (Kansas, Missouri, Iowa, and..., (410) 642-2411, ext. 5193 Baltimore Rehabilitation, Research and Development Center, Send to: Human...

5 CFR Appendix B to Part 581 - List of Agents Designated To Facilitate the Service of Legal Process on Federal Employees

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Post Office Box 2905, Fort Worth, TX 76113, (817) 885-5471 Great Plains (Kansas, Missouri, Iowa, and..., (410) 642-2411, ext. 5193 Baltimore Rehabilitation, Research and Development Center, Send to: Human...

21 CFR 184.1081 - Propionic acid.

Code of Federal Regulations, 2011 CFR

2011-04-01

... manufacturing practice conditions of use: (1) The ingredient is used as an antimicrobial agent as defined in... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Listing of Specific...

21 CFR 184.1081 - Propionic acid.

Code of Federal Regulations, 2010 CFR

2010-04-01

... manufacturing practice conditions of use: (1) The ingredient is used as an antimicrobial agent as defined in... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Listing of Specific...

N,N-Dihaloamine Explosives as Harmful Agent Defeat Materials

DTIC Science & Technology

2014-06-01

hexachloromelamine detonations .......................32 List of Figures Figure 1. Stainless steel detonation chamber...12 Figure 10. Stainless steel coupons for spore samples ....................................................................14... Stainless steel mesh (2 cm × 2 cm), as used; tube containing the screen rolled into a cone, inserted in the tube

Disaster: Planning, Preparation, Prevention.

ERIC Educational Resources Information Center

Rutherford, Christine

1990-01-01

Discusses causes of library disasters and provides several examples of disasters. Emphasis is on the importance of awareness, insurance protection, a written disaster plan, cooperation with the fire marshall and insurance agent in planning, and staff training. Several elements of the written plan are listed. (22 references) (MES)

INDUCTION OF PLANT ALLERGENS BY ENVIRONMENTAL AGENTS

EPA Science Inventory

The specific objectives of the project and the progress toward meeting these objectives are listed below:

Identify up to Three Environmental Exposures That Induce the Production of an Allergenic Protein in the Mountain Cedar Tree by Examining the Effects of Exposu...