Proposed Project Selection Method for Human Support Research and Technology Development (HSR&TD)

NASA Technical Reports Server (NTRS)

Jones, Harry

2005-01-01

The purpose of HSR&TD is to deliver human support technologies to the Exploration Systems Mission Directorate (ESMD) that will be selected for future missions. This requires identifying promising candidate technologies and advancing them in technology readiness until they are acceptable. HSR&TD must select an may of technology development projects, guide them, and either terminate or continue them, so as to maximize the resulting number of usable advanced human support technologies. This paper proposes an effective project scoring methodology to support managing the HSR&TD project portfolio. Researchers strongly disagree as to what are the best technology project selection methods, or even if there are any proven ones. Technology development is risky and outstanding achievements are rare and unpredictable. There is no simple formula for success. Organizations that are satisfied with their project selection approach typically use a mix of financial, strategic, and scoring methods in an open, established, explicit, formal process. This approach helps to build consensus and develop management insight. It encourages better project proposals by clarifying the desired project attributes. We propose a project scoring technique based on a method previously used in a federal laboratory and supported by recent research. Projects are ranked by their perceived relevance, risk, and return - a new 3 R's. Relevance is the degree to which the project objective supports the HSR&TD goal of developing usable advanced human support technologies. Risk is the estimated probability that the project will achieve its specific objective. Return is the reduction in mission life cycle cost obtained if the project is successful. If the project objective technology performs a new function with no current cost, its return is the estimated cash value of performing the new function. The proposed project selection scoring method includes definitions of the criteria, a project evaluation questionnaire, and a scoring formula.

Defense Advanced Research Projects Agency: Key Factors Drive Transition of Technologies, but Better Training and Data Dissemination Can Increase Success

DTIC Science & Technology

2015-11-01

more detail. Table 1: Overview of DARPA Programs Selected for GAO Case Study Analyses Program name Program description Advanced Wireless Networks ...Selected DARPA Programs Program name According to DARPA portfolio-level database According to GAO analysis Advanced Wireless Networks for the Soldier...with potential transition partners Achievement of clearly defined technical goals Successful transition Advanced Wireless Networks for Soldier

Selection and Prioritization of Advanced Propulsion Technologies for Future Space Missions

NASA Technical Reports Server (NTRS)

Eberle, Bill; Farris, Bob; Johnson, Les; Jones, Jonathan; Kos, Larry; Woodcock, Gordon; Brady, Hugh J. (Technical Monitor)

2002-01-01

The exploration of our solar system will require spacecraft with much greater capability than spacecraft which have been launched in the past. This is particularly true for exploration of the outer planets. Outer planet exploration requires shorter trip times, increased payload mass, and ability to orbit or land on outer planets. Increased capability requires better propulsion systems, including increased specific impulse. Chemical propulsion systems are not capable of delivering the performance required for exploration of the solar system. Future propulsion systems will be applied to a wide variety of missions with a diverse set of mission requirements. Many candidate propulsion technologies have been proposed but NASA resources do not permit development of a] of them. Therefore, we need to rationally select a few propulsion technologies for advancement, for application to future space missions. An effort was initiated to select and prioritize candidate propulsion technologies for development investment. The results of the study identified Aerocapture, 5 - 10 KW Solar Electric Ion, and Nuclear Electric Propulsion as high priority technologies. Solar Sails, 100 Kw Solar Electric Hall Thrusters, Electric Propulsion, and Advanced Chemical were identified as medium priority technologies. Plasma sails, momentum exchange tethers, and low density solar sails were identified as high risk/high payoff technologies.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacques V Hugo

This book chapter describes the considerations for the selection of advanced human–system interfaces (HSIs) for the new generation of nuclear power plants. The chapter discusses the technologies that will be needed to support highly automated nuclear power plants, while minimising demands for numbers of operational staff, reducing human error and improving plant efficiency and safety. Special attention is paid to the selection and deployment of advanced technologies in nuclear power plants (NPPs). The chapter closes with an examination of how technologies are likely to develop over the next 10–15 years and how this will affect design choices for the nuclearmore » industry.« less

Study of Turbofan Engines Designed for Low Enery Consumption

NASA Technical Reports Server (NTRS)

Neitzel, R. E.; Hirschkron, R.; Johnston, R. P.

1976-01-01

Subsonic transport turbofan engine design and technology features which have promise of improving aircraft energy consumption are described. Task I addressed the selection and evaluation of features for the CF6 family of engines in current aircraft, and growth models of these aircraft. Task II involved cycle studies and the evaluation of technology features for advanced technology turbofans, consistent with initial service in 1985. Task III pursued the refined analysis of a specific design of an advanced technology turbofan engine selected as the result of Task II studies. In all of the above, the impact upon aircraft economics, as well as energy consumption, was evaluated. Task IV summarized recommendations for technology developments which would be necessary to achieve the improvements in energy consumption identified.

Reliability and quality EEE parts issues

NASA Technical Reports Server (NTRS)

Barney, Dan; Feigenbaum, Irwin

1990-01-01

NASA policy and procedures are established which govern the selection, testing, and application of electrical, electronic, and electromechanical (EEE) parts. Recent advances in the state-of-the-art of electronic parts and associated technologies can significantly impact the electronic designs and reliability of NASA space transportation avionics. Significant issues that result from these advances are examined, including: recent advances in microelectronics technology (as applied to or considered for use in NASA projects); electron packaging technology advances (concurrent with, and as a result of, the development of the advanced microelectronic devices); availability of parts used in space avionics; and standardization and integration of parts activities between projects, centers, and contractors.

A moving baseline for evaluation of advanced coal extraction systems

NASA Technical Reports Server (NTRS)

Bickerton, C. R.; Westerfield, M. D.

1981-01-01

Results from the initial effort to establish baseline economic performance comparators for a program whose intent is to define, develop, and demonstrate advanced systems suitable for coal resource extraction beyond the year 2000 are reported. Systems used were selected from contemporary coal mining technology and from conservation conjectures of year 2000 technology. The analysis was also based on a seam thickness of 6 ft. Therefore, the results are specific to the study systems and the selected seam extended to other seam thicknesses.

A method to select human-system interfaces for nuclear power plants

DOE PAGES

Hugo, Jacques Victor; Gertman, David Ira

2015-10-19

The new generation of nuclear power plants (NPPs) will likely make use of state-of-the-art technologies in many areas of the plant. The analysis, design, and selection of advanced human–system interfaces (HSIs) constitute an important part of power plant engineering. Designers need to consider the new capabilities afforded by these technologies in the context of current regulations and new operational concepts, which is why they need a more rigorous method by which to plan the introduction of advanced HSIs in NPP work areas. Much of current human factors research stops at the user interface and fails to provide a definitive processmore » for integration of end user devices with instrumentation and control (I&C) and operational concepts. The current lack of a clear definition of HSI technology, including the process for integration, makes characterization and implementation of new and advanced HSIs difficult. This paper describes how new design concepts in the nuclear industry can be analyzed and how HSI technologies associated with new industrial processes might be considered. Furthermore, it also describes a basis for an understanding of human as well as technology characteristics that could be incorporated into a prioritization scheme for technology selection and deployment plans.« less

Recent advances in spacecraft thermal-control materials research.

NASA Technical Reports Server (NTRS)

Zerlaut, G. A.; Gilligan, J. E.; Gates, D. W.

1972-01-01

The state-of-the-art of spacecraft thermal-control materials technology has been significantly advanced during the past 4 years. Selective black coatings are discussed together with black paints, dielectric films on metal surfaces, and white radiator coatings. Criteria for the selection of thermal-control surfaces are considered, giving attention to prelaunch protection, the capability of being measured, reproducibility, simulator response, and aspects of a nonindigenous space environment. Progress in space simulation is related to vacuum technology, ultraviolet sources, solar wind simulation, and the production of protons. Advances have been made in the protection against space environmental effects, and in the development of thermal-control surfaces and pigments.

Advanced structures technology and aircraft safety

NASA Technical Reports Server (NTRS)

Mccomb, H. G., Jr.

1983-01-01

NASA research and development on advanced aeronautical structures technology related to flight safety is reviewed. The effort is categorized as research in the technology base and projects sponsored by the Aircraft Energy Efficiency (ACEE) Project Office. Base technology research includes mechanics of composite structures, crash dynamics, and landing dynamics. The ACEE projects involve development and fabrication of selected composite structural components for existing commercial transport aircraft. Technology emanating from this research is intended to result in airframe structures with improved efficiency and safety.

Lightweight, High Strength Metals With Enhanced Radiation Shielding - Technology Advancing Partnerships Challenge Project

NASA Technical Reports Server (NTRS)

Wright, Maria Clara (Compiler)

2015-01-01

The Technology Advancing Partnership (TAP) Challenge will seek to foster innovation throughout the Center by allowing the KSC workforce to identify a specific technology idea that needs improvement and to then work with an external partner to develop that technology. This Challenge will enable competitive partnerships with outside entities that will increase the value by bringing leveraged resources. The selected proposal from the University of Florida will develop new lightweight technologies with radiation mitigation for spacecraft.

78 FR 52560 - Hurricane Sandy Rebuilding Task Force-Rebuild-by-Design; Announcement of Selection of Design Teams

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

... launch Rebuild by Design and select the 10 teams. NEA has a history of supporting and facilitating design... design teams selected are the following: Interboro Partners with the New Jersey Institute of Technology.... Massachusetts Institute of Technology Center for Advanced Urbanism and the Dutch Delta Collaborative by ZUS...

15 CFR 295.6 - Criteria for selection.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Criteria for selection. 295.6 Section 295.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY...

15 CFR 295.6 - Criteria for selection.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Criteria for selection. 295.6 Section 295.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY...

15 CFR 295.6 - Criteria for selection.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Criteria for selection. 295.6 Section 295.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY...

Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomics

PubMed Central

Shi, Tujin; Su, Dian; Liu, Tao; Tang, Keqi; Camp, David G.; Qian, Wei-Jun; Smith, Richard D.

2012-01-01

Selected reaction monitoring (SRM)—also known as multiple reaction monitoring (MRM)—has emerged as a promising high-throughput targeted protein quantification technology for candidate biomarker verification and systems biology applications. A major bottleneck for current SRM technology, however, is insufficient sensitivity for e.g., detecting low-abundance biomarkers likely present at the low ng/mL to pg/mL range in human blood plasma or serum, or extremely low-abundance signaling proteins in cells or tissues. Herein we review recent advances in methods and technologies, including front-end immunoaffinity depletion, fractionation, selective enrichment of target proteins/peptides including posttranslational modifications (PTMs), as well as advances in MS instrumentation which have significantly enhanced the overall sensitivity of SRM assays and enabled the detection of low-abundance proteins at low to sub- ng/mL level in human blood plasma or serum. General perspectives on the potential of achieving sufficient sensitivity for detection of pg/mL level proteins in plasma are also discussed. PMID:22577010

Advancing the sensitivity of selected reaction monitoring-based targeted quantitative proteomics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shi, Tujin; Su, Dian; Liu, Tao

2012-04-01

Selected reaction monitoring (SRM)—also known as multiple reaction monitoring (MRM)—has emerged as a promising high-throughput targeted protein quantification technology for candidate biomarker verification and systems biology applications. A major bottleneck for current SRM technology, however, is insufficient sensitivity for e.g., detecting low-abundance biomarkers likely present at the pg/mL to low ng/mL range in human blood plasma or serum, or extremely low-abundance signaling proteins in the cells or tissues. Herein we review recent advances in methods and technologies, including front-end immunoaffinity depletion, fractionation, selective enrichment of target proteins/peptides or their posttranslational modifications (PTMs), as well as advances in MS instrumentation, whichmore » have significantly enhanced the overall sensitivity of SRM assays and enabled the detection of low-abundance proteins at low to sub- ng/mL level in human blood plasma or serum. General perspectives on the potential of achieving sufficient sensitivity for detection of pg/mL level proteins in plasma are also discussed.« less

Study of the application of advanced technologies to long-range transport aircraft. Volume 2: Research and development requirements

NASA Technical Reports Server (NTRS)

Lange, R. H.; Sturgeon, R. F.; Adams, W. E.; Bradley, E. S.; Cahill, J. F.; Eudaily, R. R.; Hancock, J. P.; Moore, J. W.

1972-01-01

Investigations were conducted to evaluate the relative benefits attainable through the exploitation of advanced technologies and to identify future research and development efforts required to permit the application of selected technologies to transport aircraft entering commercial operation in 1985. Results show that technology advances, particularly in the areas of composite materials, supercritical aerodynamics, and active control systems, will permit the development of long-range, high-payload commercial transports operating at high-subsonic speeds with direct operating costs lower than those of current aircraft. These advanced transports also achieve lower noise levels and lower engine pollutant emissions than current transports. Research and development efforts, including analytical investigations, laboratory test programs, and flight test programs, are required in essentially all technology areas to achieve the potential technology benefits.

NASA IVHM Technology Experiment for X-vehicles (NITEX)

NASA Technical Reports Server (NTRS)

Sandra, Hayden; Bajwa, Anupa

2001-01-01

The purpose of the NASA IVHM Technology Experiment for X-vehicles (NITEX) is to advance the development of selected IVHM technologies in a flight environment and to demonstrate the potential for reusable launch vehicle ground processing savings. The technologies to be developed and demonstrated include system-level and detailed diagnostics for real-time fault detection and isolation, prognostics for fault prediction, automated maintenance planning based on diagnostic and prognostic results, and a microelectronics hardware platform. Complete flight The Evolution of Flexible Insulation as IVHM consists of advanced sensors, distributed data acquisition, data processing that includes model-based diagnostics, prognostics and vehicle autonomy for control or suggested action, and advanced data storage. Complete ground IVHM consists of evolved control room architectures, advanced applications including automated maintenance planning and automated ground support equipment. This experiment will advance the development of a subset of complete IVHM.

Overview of the Advanced High Frequency Branch

NASA Technical Reports Server (NTRS)

Miranda, Felix A.

2015-01-01

This presentation provides an overview of the competencies, selected areas of research and technology development activities, and current external collaborative efforts of the NASA Glenn Research Center's Advanced High Frequency Branch.

Advanced Platform Systems Technology study. Volume 4: Technology advancement program plan

NASA Technical Reports Server (NTRS)

1983-01-01

An overview study of the major technology definition tasks and subtasks along with their interfaces and interrelationships is presented. Although not specifically indicated in the diagram, iterations were required at many steps to finalize the results. The development of the integrated technology advancement plan was initiated by using the results of the previous two tasks, i.e., the trade studies and the preliminary cost and schedule estimates for the selected technologies. Descriptions for the development of each viable technology advancement was drawn from the trade studies. Additionally, a logic flow diagram depicting the steps in developing each technology element was developed along with descriptions for each of the major elements. Next, major elements of the logic flow diagrams were time phased, and that allowed the definition of a technology development schedule that was consistent with the space station program schedule when possible. Schedules show the major milestone including tests required as described in the logic flow diagrams.

Technological progress as a driver of innovation in infant foods.

PubMed

Ferruzzi, Mario G; Neilson, Andrew P

2010-01-01

Advances in nutrition and food sciences are interrelated components of the innovative framework for infant formula and foods. While nutrition science continues to define the composition and functionality of human milk as a reference, food ingredient, formulation and processing technologies facilitate the design and delivery of nutritional and functional concepts to infant products. Expanding knowledge of both nutritive and non-nutritive components of human milk and their functionality guides selection and development of novel ingredient, formulation and processing methods to generate enhanced infant products targeting benefits including healthy growth, development as well as protection of health through the life cycle. In this chapter, identification and application of select novel ingredients/technologies will be discussed in the context of how these technological advancements have stimulated innovation in infant foods. Special focus will be given to advancements in protein technologies, as well as bioactive long-chain polyunsaturated fatty acids, prebiotics, probiotics that have allowed infant formula composition, and more critically functionality, to more closely align with that of human milk. Copyright © 2010 S. Karger AG, Basel.

Industrial storage applications overview

NASA Technical Reports Server (NTRS)

Duscha, R. A.

1980-01-01

The implementation of a technology demonstration for the food processing industry, development and technology demonstrations for selected near-term, in-plant applications and advanced industrial applications of thermal energy storage are overviewed.

Advanced extravehicular protective systems for shuttle, space station, lunar base and Mars missions.

NASA Technical Reports Server (NTRS)

Heimlich, P. F.; Sutton, J. G.; Tepper, E. H.

1972-01-01

Advances in extravehicular life support system technology will directly influence future space mission reliability and maintainability considerations. To identify required new technology areas, an appraisal of advanced portable life support system and subsystem concepts was conducted. Emphasis was placed on thermal control and combined CO2 control/O2 supply subsystems for both primary and emergency systems. A description of study methodology, concept evaluation techniques, specification requirements, and selected subsystems and systems are presented. New technology recommendations encompassing thermal control, CO2 control and O2 supply subsystems are also contained herein.

A fuel conservation study for transport aircraft utilizing advanced technology and hydrogen fuel

NASA Technical Reports Server (NTRS)

Berry, W.; Calleson, R.; Espil, J.; Quartero, C.; Swanson, E.

1972-01-01

The conservation of fossil fuels in commercial aviation was investigated. Four categories of aircraft were selected for investigation: (1) conventional, medium range, low take-off gross weight; (2) conventional, long range, high take-off gross weights; (3) large take-off gross weight aircraft that might find future applications using both conventional and advanced technology; and (4) advanced technology aircraft of the future powered with liquid hydrogen fuel. It is concluded that the hydrogen fueled aircraft can perform at reduced size and gross weight the same payload/range mission as conventionally fueled aircraft.

Research and technology 1995 annual report

NASA Technical Reports Server (NTRS)

1995-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1995 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as technology transfer activities. Major areas of research include environmental engineering, automation, robotics, advanced software, materials science, life sciences, mechanical engineering, nondestructive evaluation, and industrial engineering.

Research and Technology at the John F. Kennedy Space Center 1993

NASA Technical Reports Server (NTRS)

1993-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1993 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. Major areas of research include material science, advanced software, industrial engineering, nondestructive evaluation, life sciences, atmospheric sciences, environmental technology, robotics, and electronics and instrumentation.

The New Millenium Program: Serving Earth and Space Sciences

NASA Technical Reports Server (NTRS)

Li, Fuk K.

2000-01-01

NASA has exciting plans for space science and Earth observations during the next decade. A broad range of advanced spacecraft and measurement technologies will be needed to support these plans within the existing budget and schedule constraints. Many of these technology needs are common to both NASA's Office of Earth Science (OES) and Office of Space Sciences (OSS). Even though some breakthrough technologies have been identified to address these needs, project managers have traditionally been reluctant to incorporate them into flight programs because their inherent development risk. To accelerate the infusion of new technologies into its OES and OSS missions, NASA established the New Millennium Program (NMP). This program analyzes the capability needs of these enterprises, identifies candidate technologies to address these needs, incorporates advanced technology suites into validation flights, validates them in the relevant space environment, and then proactively infuses the validated technologies into future missions to enhance their capabilities while reducing their life cycle cost. The NMP employs a cross-enterprise Science Working Group, the NASA Enterprise science and technology roadmaps to define the capabilities needed by future Earth and Space science missions. Additional input from the science community is gathered through open workshops and peer-reviewed NASA Research Announcement (NRAs) for advanced measurement concepts. Technology development inputs from the technology organizations within NASA, other government agencies, federally funded research and development centers (FFRDC's), U.S. industry, and academia are sought to identify breakthrough technologies that might address these needs. This approach significantly extends NASA's technology infrastructure. To complement other flight test programs that develop or validate of individual components, the NMP places its highest priority on system-level validations of technology suites in the relevant space environment. This approach is not needed for all technologies, but it is usually essential to validate advanced system architectures or new measurement concepts. The NMP has recently revised its processes for defining candidate validation flights, and selecting technologies for these flights. The NMP now employs integrated project formulation teams, 'Which include scientists, technologists, and mission planners, to incorporate technology suites into candidate validation flights. These teams develop competing concepts, which can be rigorously evaluated prior to selection for flight. The technology providers for each concept are selected through an open, competitive, process during the project formulation phase. If their concept is selected for flight, they are incorporated into the Project Implementation Team, which develops, integrates, tests, launches, and operates the technology validation flight. Throughout the project implementation phase, the Implementation Team will document and disseminate their validation results to facilitate the infusion of their validated technologies into future OSS and OES science missions. The NMP has successfully launched its first two Deep Space flights for the OSS, and is currently implementing its first two Earth Orbiting flights for the OES. The next OSS and OES flights are currently being defined. Even though these flights are focused on specific Space Science and Earth Science themes, they are designed to validate a range of technologies that could benefit both enterprises, including advanced propulsion, communications, autonomous operations and navigation, multifunctional structures, microelectronics, and advanced instruments. Specific examples of these technologies will be provided in our presentation. The processes developed by the NMP also provide benefits across the Space and Earth Science enterprises. In particular, the extensive, nation-wide technology infrastructure developed by the NMP enhances the access to breakthrough technologies for both enterprises.

Technology development of fabrication techniques for advanced solar dynamic concentrators

NASA Technical Reports Server (NTRS)

Richter, Scott W.

1991-01-01

The objective of the advanced concentrator program is to develop the technology that will lead to lightweight, highly reflective, accurate, scaleable, and long lived space solar dynamic concentrators. The advanced concentrator program encompasses new and innovative concepts, fabrication techniques, materials selection, and simulated space environmental testing. Fabrication techniques include methods of fabricating the substrates and coating substrate surfaces to produce high quality optical surfaces, acceptable for further coating with vapor deposited optical films. The selected materials to obtain a high quality optical surface include microsheet glass and Eccocoat EP-3 epoxy, with DC-93-500 selected as a candidate silicone adhesive and levelizing layer. The following procedures are defined: cutting, cleaning, forming, and bonding microsheet glass. Procedures are also defined for surface cleaning, and EP-3 epoxy application. The results and analyses from atomic oxygen and thermal cycling tests are used to determine the effects of orbital conditions in a space environment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hugo, Jacques Victor; Gertman, David Ira

The new generation of nuclear power plants (NPPs) will likely make use of state-of-the-art technologies in many areas of the plant. The analysis, design, and selection of advanced human–system interfaces (HSIs) constitute an important part of power plant engineering. Designers need to consider the new capabilities afforded by these technologies in the context of current regulations and new operational concepts, which is why they need a more rigorous method by which to plan the introduction of advanced HSIs in NPP work areas. Much of current human factors research stops at the user interface and fails to provide a definitive processmore » for integration of end user devices with instrumentation and control (I&C) and operational concepts. The current lack of a clear definition of HSI technology, including the process for integration, makes characterization and implementation of new and advanced HSIs difficult. This paper describes how new design concepts in the nuclear industry can be analyzed and how HSI technologies associated with new industrial processes might be considered. Furthermore, it also describes a basis for an understanding of human as well as technology characteristics that could be incorporated into a prioritization scheme for technology selection and deployment plans.« less

Research and technology: 1994 annual report of the John F. Kennedy Space Center

NASA Technical Reports Server (NTRS)

1994-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1994 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. The Technology Programs and Commercialization Office (DE-TPO), (407) 867-3017, is responsible for publication of this report and should be contacted for any desired information regarding the advanced technology program.

A coated-wire ion-selective electrode for ionic calcium measurements

NASA Technical Reports Server (NTRS)

Hines, John W.; Arnaud, Sara; Madou, Marc; Joseph, Jose; Jina, Arvind

1991-01-01

A coated-wire ion-selective electrode for measuring ionic calcium was developed, in collaboration with Teknektron Sensor Development Corporation (TSDC). This coated wire electrode sensor makes use of advanced, ion-responsive polyvinyl chloride (PVC) membrane technology, whereby the electroactive agent is incorporated into a polymeric film. The technology greatly simplifies conventional ion-selective electrode measurement technology, and is envisioned to be used for real-time measurement of physiological and environment ionic constituents, initially calcium. A primary target biomedical application is the real-time measurement of urinary and blood calcium changes during extended exposure to microgravity, during prolonged hospital or fracture immobilization, and for osteoporosis research. Potential advanced life support applications include monitoring of calcium and other ions, heavy metals, and related parameters in closed-loop water processing and management systems. This technology provides a much simplified ionic calcium measurement capability, suitable for both automated in-vitro, in-vivo, and in-situ measurement applications, which should be of great interest to the medical, scientific, chemical, and space life sciences communities.

Preliminary assessment of industrial needs for an advanced ocean technology

NASA Technical Reports Server (NTRS)

Mourad, A. G.; Maher, K. M.; Balon, J. E.; Coyle, A. G.; Henkener, J. A.

1979-01-01

A quick-look review of selected ocean industries is presented for the purpose of providing NASA OSTA with an assessment of technology needs and market potential. The size and growth potential, needs and problem areas, technology presently used and its suppliers, are given for industries involved in deep ocean mining, petrochemicals ocean energy conversion. Supporting services such as ocean bottom surveying; underwater transportation, data collection, and work systems; and inspection and diving services are included. Examples of key problem areas that are amenable to advanced technology solutions are included. Major companies are listed.

Impacts of an advanced public transportation system : demonstration project

DOT National Transportation Integrated Search

1999-10-01

In 1997, the Ann Arbor (Michigan) Transportation Authority began deploying a set of integrated : advanced public transportation system technologies in its vehicles, stations and control center. This paper summarizes selected findings of a multidimens...

Spinoff, 1985

NASA Technical Reports Server (NTRS)

Haggerty, J. J.

1986-01-01

Mainline NASA programs, whose challenging objectives necessitate advances across a diverse scientific/technological spectrum are summarized. A representative selection of spinoff products and processes are presented and the NASA technology from which these transfers are derived, are described. The mechanisms NASA employs to foster technology utilization and stimulate interest among prospective users of the technology are detailed.

Fuel efficiency through new airframe technology

NASA Technical Reports Server (NTRS)

Leonard, R. W.

1982-01-01

In its Aircraft Energy Efficiency Program, NASA has expended approximately 200 million dollars toward development and application of advanced airframe technologies to United States's commercial transports. United States manufacturers have already been given a significant boost toward early application of advanced composite materials to control surface and empennage structures and toward selected applications of active controls and advanced aerodynamic concepts. In addition, significant progress in definition and development of innovative, but realistic systems for laminar flow control over the wings of future transports has already been made.

Applying Technology Ranking and Systems Engineering in Advanced Life Support

NASA Technical Reports Server (NTRS)

Jones, Harry; Luna, Bernadette (Technical Monitor)

2000-01-01

According to the Advanced Life Support (ALS) Program Plan, the Systems Modeling and Analysis Project (SMAP) has two important tasks: 1) prioritizing investments in ALS Research and Technology Development (R&TD), and 2) guiding the evolution of ALS systems. Investments could be prioritized simply by independently ranking different technologies, but we should also consider a technology's impact on system design. Guiding future ALS systems will require SMAP to consider many aspects of systems engineering. R&TD investments can be prioritized using familiar methods for ranking technology. The first step is gathering data on technology performance, safety, readiness level, and cost. Then the technologies are ranked using metrics or by decision analysis using net present economic value. The R&TD portfolio can be optimized to provide the maximum expected payoff in the face of uncertain future events. But more is needed. The optimum ALS system can not be designed simply by selecting the best technology for each predefined subsystem. Incorporating a new technology, such as food plants, can change the specifications of other subsystems, such as air regeneration. Systems must be designed top-down starting from system objectives, not bottom-up from selected technologies. The familiar top-down systems engineering process includes defining mission objectives, mission design, system specification, technology analysis, preliminary design, and detail design. Technology selection is only one part of systems analysis and engineering, and it is strongly related to the subsystem definitions. ALS systems should be designed using top-down systems engineering. R&TD technology selection should consider how the technology affects ALS system design. Technology ranking is useful but it is only a small part of systems engineering.

Pointing and control system enabling technology for future automated space missions

NASA Technical Reports Server (NTRS)

Dahlgren, J. B.

1978-01-01

Future automated space missions present challenging opportunities in the pointing-and-control technology disciplines. The enabling pointing-and-control system technologies for missions from 1985 to the year 2000 were identified and assessed. A generic mission set including Earth orbiter, planetary, and other missions which predominantly drive the pointing-and-control requirements was selected for detailed evaluation. Technology candidates identified were prioritized as planning options for future NASA-OAST advanced development programs. The primary technology thrusts in each candidate program were cited, and advanced development programs in pointing-and-control were recommended for the FY 80 to FY 87 period, based on these technology thrusts.

National Programs | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratoryis a shared national resource that offers access to a suite of advanced biomedical technologies, provides selected science and technology services, and maintains vast repositories of research materials available

National Programs | FNLCR Staging

Cancer.gov

The Frederick National Lab (FNL) is a shared national resource that offers access to a suite of advanced biomedical technologies, provides selected science and technology services, and maintains vast repositories of research materials available to bi

The advance of technology and the scientific commons.

PubMed

Nelson, Richard R

2003-08-15

The advance of technology proceeds through an evolutionary process, with many different new departures in competition with each other and with prevailing practice, and with ex-post selection determining the winners and losers. In modern times what gives power to the process is the strong base of scientific and technological understanding and technique that guides the efforts of those seeking to advance the technology. Most of that base is part of a commons open to all who have expertise in a field. The proprietary aspects of technology traditionally have comprised a small topping on the commons. But recently parts of the commons have become privatized. While the justification for the policies and actions that have spurred privatization of the commons is that this will spur technological progress, the argument here is that the result can be just the opposite.

Advanced on-site power plant development technology program

NASA Technical Reports Server (NTRS)

1984-01-01

A 30-cell, full area short stack containing advanced cell features was tested for 2900 hours. A stack acid addition approach was selected and will be evaluated on the stack at 5000 hours test time. A brassboard inverter was designed and fabrication was initiated. Evaluation of this brassboard inverter will take place in 1984. A Teflon coated commercial heat exchanger was selected as the preferred approach for the acid condenser. A reformer catalyst with significantly less pressure drop and equivalent performance relative to the 40-K baseline catalyst was selected for the development reformer. The early 40-kW field power plant history was reviewed and adjustments were made to the On-Site Technology Development Program to address critical component issues.

Modeling of Spacecraft Advanced Chemical Propulsion Systems

NASA Technical Reports Server (NTRS)

Benfield, Michael P. J.; Belcher, Jeremy A.

2004-01-01

This paper outlines the development of the Advanced Chemical Propulsion System (ACPS) model for Earth and Space Storable propellants. This model was developed by the System Technology Operation of SAIC-Huntsville for the NASA MSFC In-Space Propulsion Project Office. Each subsystem of the model is described. Selected model results will also be shown to demonstrate the model's ability to evaluate technology changes in chemical propulsion systems.

QFD emphasis of IME design

NASA Astrophysics Data System (ADS)

Erickson, C. M.; Martinez, A.

1993-06-01

The 1992 Integrated Modular Engine (IME) design concept, proposed to the Air Force Space Systems Division as a candidate for a National Launch System (NLS) upper stage, emphasized a detailed Quality Functional Deployment (QFD) procedure which set the basis for its final selection. With a list of engine requirements defined and prioritized by the customer, a QFD procedure was implemented where the characteristics of a number of engine and component configurations were assessed for degree of requirement satisfaction. The QFD process emphasized operability, cost, reliability and performance, with relative importance specified by the customer. Existing technology and near-term advanced technology were surveyed to achieve the required design strategies. In the process, advanced nozzles, advanced turbomachinery, valves, controls, and operational procedures were evaluated. The integrated arrangement of three conventional bell nozzle thrust chambers with two advanced turbopump sets selected as the configuration meeting all requirements was rated significantly ahead of the other candidates, including the Aerospike and horizontal flow nozzle configurations.

15 CFR 295.5 - Use of pre-proposals in the selection process.

Code of Federal Regulations, 2012 CFR

2012-01-01

... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED... preparation costs incurred by proposers and to make the selection process more efficient, NIST may use...

15 CFR 295.5 - Use of pre-proposals in the selection process.

Code of Federal Regulations, 2013 CFR

2013-01-01

... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED... preparation costs incurred by proposers and to make the selection process more efficient, NIST may use...

15 CFR 295.5 - Use of pre-proposals in the selection process.

Code of Federal Regulations, 2011 CFR

2011-01-01

... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED... preparation costs incurred by proposers and to make the selection process more efficient, NIST may use...

15 CFR 295.5 - Use of pre-proposals in the selection process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED... preparation costs incurred by proposers and to make the selection process more efficient, NIST may use...

15 CFR 295.5 - Use of pre-proposals in the selection process.

Code of Federal Regulations, 2014 CFR

2014-01-01

... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED... preparation costs incurred by proposers and to make the selection process more efficient, NIST may use...

NASA Radioisotope Power System Program - Technology and Flight Systems

NASA Technical Reports Server (NTRS)

Sutliff, Thomas J.; Dudzinski, Leonard A.

2009-01-01

NASA sometimes conducts robotic science missions to solar system destinations for which the most appropriate power source is derived from thermal-to-electrical energy conversion of nuclear decay of radioactive isotopes. Typically the use of a radioisotope power system (RPS) has been limited to medium and large-scale missions, with 26 U,S, missions having used radioisotope power since 1961. A research portfolio of ten selected technologies selected in 2003 has progressed to a point of maturity, such that one particular technology may he considered for future mission use: the Advanced Stirling Converter. The Advanced Stirling Radioisotope Generator is a new power system in development based on this Stirling cycle dynamic power conversion technology. This system may be made available for smaller, Discovery-class NASA science missions. To assess possible uses of this new capability, NASA solicited and funded nine study teams to investigate unique opportunities for exploration of potential destinations for small Discovery-class missions. The influence of the results of these studies and the ongoing development of the Advanced Stirling Radioisotope Generator system are discussed in the context of an integrated Radioisotope Power System program. Discussion of other and future technology investments and program opportunities are provided.

Battery Separator Characterization and Evaluation Procedures for NASA's Advanced Lithium-Ion Batteries

NASA Technical Reports Server (NTRS)

Baldwin, Richard S.; Bennet, William R.; Wong, Eunice K.; Lewton, MaryBeth R.; Harris, Megan K.

2010-01-01

To address the future performance and safety requirements for the electrical energy storage technologies that will enhance and enable future NASA manned aerospace missions, advanced rechargeable, lithium-ion battery technology development is being pursued within the scope of the NASA Exploration Technology Development Program s (ETDP's) Energy Storage Project. A critical cell-level component of a lithium-ion battery which significantly impacts both overall electrochemical performance and safety is the porous separator that is sandwiched between the two active cell electrodes. To support the selection of the optimal cell separator material(s) for the advanced battery technology and chemistries under development, laboratory characterization and screening procedures were established to assess and compare separator material-level attributes and associated separator performance characteristics.

Technology development program for an advanced microsheet glass concentrator

NASA Technical Reports Server (NTRS)

Richter, Scott W.; Lacy, Dovie E.

1990-01-01

Solar Dynamic Space Power Systems are candidate electrical power generating systems for future NASA missions. One of the key components in a solar dynamic power system is the concentrator which collects the sun's energy and focuses it into a receiver. In 1985, the NASA Lewis Research Center initiated the Advanced Solar Dynamic Concentrator Program with funding from NASA's Office of Aeronautics and Space Technology (OAST). The objectives of the Advanced Concentrator Program is to develop the technology that will lead to lightweight, highly reflective, accurate, scaleable, and long lived (7 to 10 years) space solar dynamic concentrators. The Advanced Concentrator Program encompasses new and innovative concepts, fabrication techniques, materials selection, and simulated space environmental testing. The Advanced Microsheet Glass Concentrator Program, a reflector concept, that is currently being investigated both in-house and under contract is discussed.

Data and Tools | Transportation Research | NREL

Science.gov Websites

Projection Tool Lite Tool for projecting consumer demand for electric vehicle charging infrastructure at the technologies or for selecting a technology to invest in. Transportation-Related Consumer Preference Data Consumer preference data related to alternative fuel and advanced vehicle technologies to support the

Hybrid Propulsion Technology Program, phase 1. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1989-01-01

The study program was contracted to evaluate concepts of hybrid propulsion, select the most optimum, and prepare a conceptual design package. Further, this study required preparation of a technology definition package to identify hybrid propulsion enabling technologies and planning to acquire that technology in Phase 2 and demonstrate that technology in Phase 3. Researchers evaluated two design philosophies for Hybrid Rocket Booster (HRB) selection. The first is an ASRM modified hybrid wherein as many components/designs as possible were used from the present Advanced Solid Rocket Motor (ASRM) design. The second was an entirely new hybrid optimized booster using ASRM criteria as a point of departure, i.e., diameter, thrust time curve, launch facilities, and external tank attach points. Researchers selected the new design based on the logic of optimizing a hybrid booster to provide NASA with a next generation vehicle in lieu of an interim advancement over the ASRM. The enabling technologies for hybrid propulsion are applicable to either and vehicle design may be selected at a downstream point (Phase 3) at NASA's discretion. The completion of these studies resulted in ranking the various concepts of boosters from the RSRM to a turbopump fed (TF) hybrid. The scoring resulting from the Figure of Merit (FOM) scoring system clearly shows a natural growth path where the turbopump fed solid liquid staged combustion hybrid provides maximized payload and the highest safety, reliability, and low life cycle costing.

Research and Technology 1996: Innovation in Time and Space

NASA Technical Reports Server (NTRS)

1996-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1996 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities.

Mission operations technology

NASA Astrophysics Data System (ADS)

Varsi, Giulio

In the last decade, the operation of a spacecraft after launch has emerged as a major component of the total cost of the mission. This trend is sustained by the increasing complexity, flexibility, and data gathering capability of the space assets and by their greater reliability and consequent longevity. The trend can, however, be moderated by the progressive transfer of selected functions from the ground to the spacecraft and by application, on the ground, of new technology. Advances in ground operations derive from the introduction in the mission operations environment of advanced microprocessor-based workstations in the class of a few million instructions per second and from the selective application of artificial intelligence technology. In the last few years a number of these applications have been developed, tested in operational settings and successfully demonstrated to users. Some are now being integrated in mission operations facilities. An analysis of mission operations indicates that the key areas are: concurrent control of multiple missions; automated/interactive production of command sequences of high integrity at low cost; automated monitoring of spacecraft health and automated aides for fault diagnosis; automated allocation of resources; automated processing of science data; and high-fidelity, high-speed spacecraft simulation. Examples of major advances in selected areas are described.

Impact of future fuel properties on aircraft engines and fuel systems

NASA Technical Reports Server (NTRS)

Rudey, R. A.; Grobman, J. S.

1978-01-01

This paper describes and discusses the propulsion-system problems that will most likely be encountered if the specifications of hydrocarbon-based jet fuels must undergo significant changes in the future and, correspondingly, the advances in technology that will be required to minimize the adverse impact of these problems. Several investigations conducted are summarized. Illustrations are used to describe the relative effects of selected fuel properties on the behavior of propulsion-system components and fuel systems. The selected fuel properties are those that are most likely to be relaxed in future fuel specifications. Illustrations are also used to describe technological advances that may be needed in the future. Finally, the technological areas needing the most attention are described, and programs that are under way to address these needs are briefly discussed.

Advanced technology payoffs for future rotorcraft, commuter aircraft, cruise missile, and APU propulsion systems

NASA Technical Reports Server (NTRS)

Turk, M. A.; Zeiner, P. K.

1986-01-01

In connection with the significant advances made regarding the performance of larger gas turbines, challenges arise concerning the improvement of small gas turbine engines in the 250 to 1000 horsepower range. In response to these challenges, the NASA/Army-sponsored Small Engine Component Technology (SECT) study was undertaken with the objective to identify the engine cycle, configuration, and component technology requirements for the substantial performance improvements desired in year-2000 small gas turbine engines. In the context of this objective, an American turbine engine company evaluated engines for four year-2000 applications, including a rotorcraft, a commuter aircraft, a supersonic cruise missile, and an auxiliary power unit (APU). Attention is given to reference missions, reference engines, reference aircraft, year-2000 technology projections, cycle studies, advanced engine selections, and a technology evaluation.

An Overview and Status of NASA's Radioisotope Power Conversion Technology NRA

NASA Technical Reports Server (NTRS)

Anderson, David J.; Wong, Wayne A.; Tuttle, Karen L.

2005-01-01

NASA's Advanced Radioisotope Power Systems (RPS) development program is developing next generation radioisotope power conversion technologies that will enable future missions that have requirements that can not be met by either photovoltaic systems or by current Radioisotope Power System (RPS) technology. The Advanced Power Conversion Research and Technology project of the Advanced RPS development program is funding research and technology activities through the NASA Research Announcement (NRA) 02- OSS-01, "Research Opportunities in Space Science 2002" entitled "Radioisotope Power Conversion Technology" (RPCT), 13 August 2002. The objective of the RPCT NRA is to advance the development of radioisotope power conversion technologies to provide significant improvements over the state-of-practice General Purpose Heat Source/Radioisotope Thermoelectric Generator by providing significantly higher efficiency to reduce the number of radioisotope fuel modules, and increase specific power (watts/kilogram). Other Advanced RPS goals include safety, long-life, reliability, scalability, multi-mission capability, resistance to radiation, and minimal interference with the scientific payload. These advances would enable a factor of 2 to 4 decrease in the amount of fuel required to generate electrical power. The RPCT NRA selected advanced RPS power conversion technology research and development proposals in the following three areas: innovative RPS power conversion research, RPS power conversion technology development in a nominal 100We scale; and, milliwatt/multi-watt RPS (mWRPS) power conversion research. Ten RPCT NRA contracts were awarded in 2003 in the areas of Brayton, Stirling, thermoelectric (TE), and thermophotovoltaic (TPV) power conversion technologies. This paper will provide an overview of the RPCT NRA, and a brief summary of accomplishments over the first 18 months but focusing on advancements made over the last 6 months.

A Focus on "Hands-On," Learner-Centered Technology at The Citadel

ERIC Educational Resources Information Center

DeRoma, Virginia; Nida, Steve

2004-01-01

While advances in technology have enhanced the quality and variety of visual presentations in teaching, most instructors find themselves teaching to a generation of students who are difficult to dazzle. Although the innovative use of technology in and outside of the classroom is a challenge, selecting practices that optimize technology as a tool…

Advanced Subsonic Airplane Design and Economic Studies

NASA Technical Reports Server (NTRS)

Liebeck, Robert H.; Andrastek, Donald A.; Chau, Johnny; Girvin, Raquel; Lyon, Roger; Rawdon, Blaine K.; Scott, Paul W.; Wright, Robert A.

1995-01-01

A study was made to examine the effect of advanced technology engines on the performance of subsonic airplanes and provide a vision of the potential which these advanced engines offered. The year 2005 was selected as the entry-into-service (EIS) date for engine/airframe combination. A set of four airplane classes (passenger and design range combinations) that were envisioned to span the needs for the 2005 EIS period were defined. The airframes for all classes were designed and sized using 2005 EIS advanced technology. Two airplanes were designed and sized for each class: one using current technology (1995) engines to provide a baseline, and one using advanced technology (2005) engines. The resulting engine/airframe combinations were compared and evaluated on the basis on sensitivity to basic engine performance parameters (e.g. SFC and engine weight) as well as DOC+I. The advanced technology engines provided significant reductions in fuel burn, weight, and wing area. Average values were as follows: reduction in fuel burn = 18%, reduction in wing area = 7%, and reduction in TOGW = 9%. Average DOC+I reduction was 3.5% using the pricing model based on payload-range index and 5% using the pricing model based on airframe weight. Noise and emissions were not considered.

Noninvasive imaging systems for gametes and embryo selection in IVF programs: a review.

PubMed

Omidi, Marjan; Faramarzi, Azita; Agharahimi, Azam; Khalili, Mohammad Ali

2017-09-01

Optimizing the efficiency of the in vitro fertilization procedure by improving pregnancy rates and reducing the risks of multiple pregnancies simultaneously are the primary goals of the current assisted reproductive technology program. With the move to single embryo transfers, the need for more cost-effective and noninvasive methods for embryo selection prior to transfer is paramount. These aims require advancement in a more acquire gametes/embryo testing and selection procedures using high-tech devices. Therefore, the aim of the present review is to evaluate the efficacy of noninvasive imaging systems in the current literatures, focusing on the potential clinical application in infertile patients undergoing assisted reproductive technology treatments. In this regards, three advanced imaging systems of motile sperm organelle morphology examination, polarization microscopy and time-lapse monitoring for the best selection of the gametes and preimplantation embryos are introduced in full. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

Advanced coal cleaning meets acid rain emission limits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boron, D.J.; Matoney, J.P.; Albrecht, M.C.

1987-03-01

The following processes were selected for study: fine-coal, heavy-medium cyclone separation/flotation, advanced flotation, Dow true heavy liquid separation, Advanced Energy Dynamics (AED) electrostatic separation, and National Research Council of Canada oil agglomeration. Advanced coal cleaning technology was done for the state of New York to investigate methods to use high sulfur coal in view of anticipated lower SO/sub 2/ emission limits.

Advanced composites technology program

NASA Technical Reports Server (NTRS)

Davis, John G., Jr.

1993-01-01

This paper provides a brief overview of the NASA Advanced Composites Technology (ACT) Program. Critical technology issues that must be addressed and solved to develop composite primary structures for transport aircraft are delineated. The program schedule and milestones are included. Work completed in the first 3 years of the program indicates the potential for achieving composite structures that weigh less and are cost effective relative to conventional aluminum structure. Selected technical accomplishments are noted. Readers who are seeking more in-depth technical information should study the other papers included in these proceedings.

NASA Radioisotope Power Conversion Technology NRA Overview

NASA Technical Reports Server (NTRS)

Anderson, David J.

2005-01-01

The focus of the National Aeronautics and Space Administration's (NASA) Radioisotope Power Systems (RPS) Development program is aimed at developing nuclear power and technologies that would improve the effectiveness of space science missions. The Radioisotope Power Conversion Technology (RPCT) NASA Research Announcement (NRA) is an important mechanism through which research and technology activities are supported in the Advanced Power Conversion Research and Technology project of the Advanced Radioisotope Power Systems Development program. The purpose of the RPCT NRA is to advance the development of radioisotope power conversion technologies to provide higher efficiencies and specific powers than existing systems. These advances would enable a factor of two to four decrease in the amount of fuel and a reduction of waste heat required to generate electrical power, and thus could result in more cost effective science missions for NASA. The RPCT NRA selected advanced RPS power conversion technology research and development proposals in the following three areas: innovative RPS power conversion research, RPS power conversion technology development in a nominal 100 W(sub e) scale; and, milliwatt/multi-watt RPS (mWRPS) power conversion research. Ten RPCT NRA contracts were awarded in 2003 in the areas of Brayton, Stirling, thermoelectric (TE), and thermophotovoltaic (TPV) power conversion technologies. This paper will provide an overview of the RPCT NRA, a summary of the power conversion technologies approaches being pursued, and a brief digest of first year accomplishments.

NASA Radioisotope Power Conversion Technology NRA Overview

NASA Technical Reports Server (NTRS)

Anderson, David J.

2005-01-01

The focus of the National Aeronautics and Space Administration s (NASA) Radioisotope Power Systems (RPS) Development program is aimed at developing nuclear power and technologies that would improve the effectiveness of space science missions. The Radioisotope Power Conversion Technology (RPCT) NASA Research Announcement (NRA) is an important mechanism through which research and technology activities are supported in the Advanced Power Conversion Research and Technology project of the Advanced Radioisotope Power Systems Development program. The purpose of the RPCT NRA is to advance the development of radioisotope power conversion technologies to provide higher efficiencies and specific powers than existing systems. These advances would enable a factor of 2 to 4 decrease in the amount of fuel and a reduction of waste heat required to generate electrical power, and thus could result in more cost effective science missions for NASA. The RPCT NRA selected advanced RPS power conversion technology research and development proposals in the following three areas: innovative RPS power conversion research, RPS power conversion technology development in a nominal 100We scale; and, milliwatt/multi-watt RPS (mWRPS) power conversion research. Ten RPCT NRA contracts were awarded in 2003 in the areas of Brayton, Stirling, thermoelectric (TE), and thermophotovoltaic (TPV) power conversion technologies. This paper will provide an overview of the RPCT NRA, a summary of the power conversion technologies approaches being pursued, and a brief digest of first year accomplishments.

Application of advanced technologies to small, short-haul aircraft

NASA Technical Reports Server (NTRS)

Andrews, D. G.; Brubaker, P. W.; Bryant, S. L.; Clay, C. W.; Giridharadas, B.; Hamamoto, M.; Kelly, T. J.; Proctor, D. K.; Myron, C. E.; Sullivan, R. L.

1978-01-01

The results of a preliminary design study which investigates the use of selected advanced technologies to achieve low cost design for small (50-passenger), short haul (50 to 1000 mile) transports are reported. The largest single item in the cost of manufacturing an airplane of this type is labor. A careful examination of advanced technology to airframe structure was performed since one of the most labor-intensive parts of the airplane is structures. Also, preliminary investigation of advanced aerodynamics flight controls, ride control and gust load alleviation systems, aircraft systems and turbo-prop propulsion systems was performed. The most beneficial advanced technology examined was bonded aluminum primary structure. The use of this structure in large wing panels and body sections resulted in a greatly reduced number of parts and fasteners and therefore, labor hours. The resultant cost of assembled airplane structure was reduced by 40% and the total airplane manufacturing cost by 16% - a major cost reduction. With further development, test verification and optimization appreciable weight saving is also achievable. Other advanced technology items which showed significant gains are as follows: (1) advanced turboprop-reduced block fuel by 15.30% depending on range; (2) configuration revisions (vee-tail)-empennage cost reduction of 25%; (3) leading-edge flap addition-weight reduction of 2500 pounds.

2015 Accomplishments Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

This report covers selected highlights from the four research pathways in the LWRS Program: Materials Aging and Degradation; Risk-Informed Safety Margin Characterization; Advanced Instrumentation, Information, and Control Systems Technologies; and Reactor Safety Technologies, as well as a look-ahead at planned activities for 2017.

2016 Accomplishments Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

This report covers selected highlights from the four research pathways in the LWRS Program: Materials Aging and Degradation; Risk-Informed Safety Margin Characterization; Advanced Instrumentation, Information, and Control Systems Technologies; and Reactor Safety Technologies, as well as a look-ahead at planned activities for 2017.

A Selective Meta-Analysis on the Relative Incidence of Discrete Affective States during Learning with Technology

ERIC Educational Resources Information Center

D'Mello, Sidney

2013-01-01

The last decade has witnessed considerable interest in the investigation of the affective dimensions of learning and in the development of advanced learning technologies that automatically detect and respond to student affect. Identifying the affective states that students experience in technology-enhanced learning contexts is a fundamental…

Communicating Biotech Advances: Fiction versus Reality.

PubMed

Małyska, Aleksandra; Bolla, Robert; Twardowski, Tomasz

2018-02-01

Bioscience novels use selected technologies of genetic engineering and synthetic biology to create entertaining stories. These novels are usually based on scientific knowledge, but they may arouse public concerns about technology and drive public reluctance to accept innovative technologies. The scientific community must adopt more efficient communication and transparency. Copyright © 2017 Elsevier Ltd. All rights reserved.

Progress in the Development of Direct Osmotic Concentration Wastewater Recovery Process for Advanced Life Support Systems

NASA Technical Reports Server (NTRS)

Cath, Tzahi Y.; Adams, Dean V.; Childress, Amy; Gormly, Sherwin; Flynn, Michael

2005-01-01

Direct osmotic concentration (DOC) has been identified as a high potential technology for recycling of wastewater to drinking water in advanced life support (ALS) systems. As a result the DOC process has been selected for a NASA Rapid Technology Development Team (RTDT) effort. The existing prototype system has been developed to a Technology Readiness Level (TRL) 3. The current project focuses on advancing the development of this technology from TRL 3 to TRL 6 (appropriate for human rated testing). A new prototype of a DOC system is been designed and fabricated that addresses the deficiencies encountered during the testing of the original system and allowing the new prototype to achieve TRL 6. Background information is provided about the technologies investigated and their capabilities, results from preliminary tests, and the milestones plan and activities for the RTDT program intended to develop a second generation prototype of the DOC system.

ADVANCED TOOLS FOR ASSESSING SELECTED PRESCRIPTION AND ILLICIT DRUGS IN TREATED SEWAGE EFFLUENTS AND SOURCE WATERS

EPA Science Inventory

The purpose of this poster is to present the application and assessment of advanced technologies in a real-world environment - wastewater effluent and source waters - for detecting six drugs (azithromycin, fluoxetine, omeprazole, levothyroxine, methamphetamine, and methylenedioxy...

Scoping Studies to Evaluate the Benefits of an Advanced Dry Feed System on the Use of Low-Rank Coal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rader, Jeff; Aguilar, Kelly; Aldred, Derek

2012-11-30

This report describes the development of the design of an advanced dry feed system that was carried out under Task 4.0 of Cooperative Agreement DE-FE0007902 with the US DOE, “Scoping Studies to Evaluate the Benefits of an Advanced Dry Feed System on the use of Low- Rank Coal.” The resulting design will be used for the advanced technology IGCC case with 90% carbon capture for sequestration to be developed under Task 5.0 of the same agreement. The scope of work covered coal preparation and feeding up through the gasifier injector. Subcomponents have been broken down into feed preparation (including grindingmore » and drying), low pressure conveyance, pressurization, high pressure conveyance, and injection. Pressurization of the coal feed is done using Posimetric1 Feeders sized for the application. In addition, a secondary feed system is described for preparing and feeding slag additive and recycle fines to the gasifier injector. This report includes information on the basis for the design, requirements for down selection of the key technologies used, the down selection methodology and the final, down selected design for the Posimetric Feed System, or PFS.« less

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

PubMed Central

Haber, Daniel A.; Velculescu, Victor E.

2015-01-01

The ability to study nonhematologic cancers through noninvasive sampling of blood is one of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven both by major technologic advances, including the isolation of intact cancer cells and the analysis of cancer cell–derived DNA from blood samples, and by the increasing application of molecularly driven therapeutics, which rely on such accurate and timely measurements of critical biomarkers. Moreover, the dramatic efficacy of these potent cancer therapies drives the selection for additional genetic changes as tumors acquire drug resistance, necessitating repeated sampling of cancer cells to adjust therapy in response to tumor evolution. Together, these advanced noninvasive diagnostic capabilities and their applications in guiding precision cancer therapies are poised to change the ways in which we select and monitor cancer treatments. Significance Recent advances in technologies to analyze circulating tumor cells and circulating tumor DNA are setting the stage for real-time, noninvasive monitoring of cancer and providing novel insights into cancer evolution, invasion, and metastasis. PMID:24801577

Using Technology Readiness Level (TRL), Life Cycle Cost (LCC), and Other Metrics to Supplement Equivalent System Mass (ESM) in Advanced Life Support (ALS)

NASA Technical Reports Server (NTRS)

Jones, Harry

2003-01-01

The ALS project plan goals are reducing cost, improving performance, and achieving flight readiness. ALS selects projects to advance the mission readiness of low cost, high performance technologies. The role of metrics is to help select good projects and report progress. The Equivalent Mass (EM) of a system is the sum of the estimated mass of the hardware, of its required materials and spares, and of the pressurized volume, power supply, and cooling system needed to support the hardware in space. EM is the total payload launch mass needed to provide and support a system. EM is directly proportional to the launch cost.

Recent advances on the encoding and selection methods of DNA-encoded chemical library.

PubMed

Shi, Bingbing; Zhou, Yu; Huang, Yiran; Zhang, Jianfu; Li, Xiaoyu

2017-02-01

DNA-encoded chemical library (DEL) has emerged as a powerful and versatile tool for ligand discovery in chemical biology research and in drug discovery. Encoding and selection methods are two of the most important technological aspects of DEL that can dictate the performance and utilities of DELs. In this digest, we have summarized recent advances on the encoding and selection strategies of DEL and also discussed the latest developments on DNA-encoded dynamic library, a new frontier in DEL research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Boron-selective reactions as powerful tools for modular synthesis of diverse complex molecules.

PubMed

Xu, Liang; Zhang, Shuai; Li, Pengfei

2015-12-21

In the context of modular and rapid construction of molecular diversity and complexity for applications in organic synthesis, biomedical and materials sciences, a generally useful strategy has emerged based on boron-selective chemical transformations. In the last decade, these types of reactions have evolved from proof-of-concept to some advanced applications in the efficient preparation of complex natural products and even automated precise manufacturing on the molecular level. These advances have shown the great potential of boron-selective reactions in simplifying synthetic design and experimental operations, and should inspire new developments in related chemical and technological areas. This tutorial review will highlight the original contributions and representative advances in this emerging field.

[New drug development by innovative drug administration--"change" in pharmaceutical field].

PubMed

Nagai, T

1997-11-01

New drug development can be made by providing products of higher "selectivity for the drug" for medical treatment. There are two ways for the approach to get higher "selectivity of drug": 1) discovery of new compounds with high selectivity of drug; 2) innovation of new drug administration, that is new formulation and/or method with high selectivity of drug by integration and harmonization of various hard/soft technologies. An extensive increase of biological information and advancement of surrounding science and technology may modify the situation as the latter overcomes the former in the 21 century. As the science and technology in the 21 century is said to be formed on "3H", that is, 1. hybrid; 2. hi-quality; 3. husbandry, the new drug development by innovative drug administration is exactly based on the science and technology of 3H. Its characteristic points are interdisciplinary/interfusion, international, of philosophy/ethics, and systems of hard/hard/heart. From these points of view, not only the advance of unit technology but also a revolution in thinking way should be "must" subjects. To organize this type of research well, a total research activity such as ROR (research on research) might take an important and efficient role. Here the key words are the "Optimization technology" and "Change in Pharmaceutical Fields." As some examples of new drug innovation, our trials on several topical mucosal adhesive dosage forms and parenteral administration of peptide drugs such as insulin and erythropoietin will be described.

Aerospace induction motor actuators driven from a 20-kHz power link

NASA Technical Reports Server (NTRS)

Hansen, Irving G.

1990-01-01

Aerospace electromechanical actuators utilizing induction motors are under development in sizes up to 40 kW. While these actuators have immediate application to the Advanced Launch System (ALS) program, several potential applications are currently under study including the Advanced Aircraft Program. Several recent advances developed for the Space Station Freedom have allowed induction motors to be selected as a first choice for such applications. Among these technologies are bi-directional electronics and high frequency power distribution techniques. Each of these technologies are discussed with emphasis on their impact upon induction motor operation.

Small Engine Component Technology (SECT) study. Program report

NASA Technical Reports Server (NTRS)

Almodovar, E.; Exley, T.; Kaehler, H.; Schneider, W.

1986-01-01

The study was conducted to identify high payoff technologies for year 2000 small gas turbine applications and to provide a technology plan for guiding future research and technology efforts. A regenerative cycle turboprop engine was selected for a 19 passenger commuter aircraft application. A series of engines incorporating eight levels of advanced technologies were studied and their impact on aircraft performance was evaluated. The study indicated a potential reduction in fuel burn of 38.3 percent. At $1.00 per gallon fuel price, a potential DOC benefit of 12.5 percent would be achieved. At $2.00 per gallon, the potential DOC benefit would increase to 17.0 percent. Four advanced technologies are recommended and appropriate research and technology programs were established to reach the year 2000 goals.

Impact for the 80's: Proceedings of a Conference on Selected Technology for Business and Industry

NASA Technical Reports Server (NTRS)

1980-01-01

Various aspects of advanced energy technology are discussed. Specific emphasis is given to: aircraft propulsion; wind power commercialization; materials and structures, lubrication and bearings; Stirling and gas turbine engines; and electric and hybrid vehicles.

Application of NASA's advanced life support technologies in polar regions

NASA Astrophysics Data System (ADS)

Bubenheim, D. L.; Lewis, C.

1997-01-01

NASA's advanced life support technologies are being combined with Arctic science and engineering knowledge in the Advanced Life Systems for Extreme Environments (ALSEE) project. This project addresses treatment and reduction of waste, purification and recycling of water, and production of food in remote communities of Alaska. The project focus is a major issue in the state of Alaska and other areas of the Circumpolar North; the health and welfare of people, their lives and the subsistence lifestyle in remote communities, care for the environment, and economic opportunity through technology transfer. The challenge is to implement the technologies in a manner compatible with the social and economic structures of native communities, the state, and the commercial sector. NASA goals are technology selection, system design and methods development of regenerative life support systems for planetary and Lunar bases and other space exploration missions. The ALSEE project will provide similar advanced technologies to address the multiple problems facing the remote communities of Alaska and provide an extreme environment testbed for future space applications. These technologies have never been assembled for this purpose. They offer an integrated approach to solving pressing problems in remote communities.

Titanium and advanced composite structures for a supersonic cruise arrow wing configuration

NASA Technical Reports Server (NTRS)

Turner, M. J.; Hoy, J. M.

1976-01-01

Structural design studies were made, based on current technology and on an estimate of technology to be available in the mid 1980's, to assess the relative merits of structural concepts and materials for an advanced arrow wing configuration cruising at Mach 2.7. Preliminary studies were made to insure compliance of the configuration with general design criteria, integrate the propulsion system with the airframe, and define an efficient structural arrangement. Material and concept selection, detailed structural analysis, structural design and airplane mass analysis were completed based on current technology. Based on estimated future technology, structural sizing for strength and a preliminary assessment of the flutter of a strength designed composite structure were completed. An advanced computerized structural design system was used, in conjunction with a relatively complex finite element model, for detailed analysis and sizing of structural members.

ADVANCED TOOLS FOR ASSESSING SELECTED PRESCRIPTION AND ILLICIT DRUGS IN TREATED SEWAGE EFFLUENTS AND SOURCE WATERS

EPA Science Inventory

The purpose of this poster is to present the application and assessment of advanced state-of-the-art technologies in a real-world environment - wastewater effluent and source waters - for detecting six drugs [azithromycin, fluoxetine, omeprazole, levothyroxine, methamphetamine, m...

Advanced supersonic propulsion study. [with emphasis on noise level reduction

NASA Technical Reports Server (NTRS)

Sabatella, J. A. (Editor)

1974-01-01

A study was conducted to determine the promising propulsion systems for advanced supersonic transport application, and to identify the critical propulsion technology requirements. It is shown that noise constraints have a major effect on the selection of the various engine types and cycle parameters. Several promising advanced propulsion systems were identified which show the potential of achieving lower levels of sideline jet noise than the first generation supersonic transport systems. The non-afterburning turbojet engine, utilizing a very high level of jet suppression, shows the potential to achieve FAR 36 noise level. The duct-heating turbofan with a low level of jet suppression is the most attractive engine for noise levels from FAR 36 to FAR 36 minus 5 EPNdb, and some series/parallel variable cycle engines show the potential of achieving noise levels down to FAR 36 minus 10 EPNdb with moderate additional penalty. The study also shows that an advanced supersonic commercial transport would benefit appreciably from advanced propulsion technology. The critical propulsion technology needed for a viable supersonic propulsion system, and the required specific propulsion technology programs are outlined.

Cogeneration Technology Alternatives Study (CTAS). Volume 3: Energy conversion system characteristics

NASA Technical Reports Server (NTRS)

1980-01-01

Six current and thirty-six advanced energy conversion systems were defined and combined with appropriate balance of plant equipment. Twenty-six industrial processes were selected from among the high energy consuming industries to serve as a frame work for the study. Each conversion system was analyzed as a cogenerator with each industrial plant. Fuel consumption, costs, and environmental intrusion were evaluated and compared to corresponding traditional values. The advanced energy conversion technologies indicated reduced fuel consumption, costs, and emissions. Fuel energy savings of 10 to 25 percent were predicted compared to traditional on site furnaces and utility electricity. With the variety of industrial requirements, each advanced technology had attractive applications. Fuel cells indicated the greatest fuel energy savings and emission reductions. Gas turbines and combined cycles indicated high overall annual savings. Steam turbines and gas turbines produced high estimated returns. In some applications, diesels were most efficient. The advanced technologies used coal derived fuels, or coal with advanced fluid bed combustion or on site gasifications. Data and information for both current and advanced energy conversion technology are presented. Schematic and physical descriptions, performance data, equipment cost estimates, and predicted emissions are included. Technical developments which are needed to achieve commercialization in the 1985-2000 period are identified.

Photonic technology revolution influence on the defence area

NASA Astrophysics Data System (ADS)

Galas, Jacek; Litwin, Dariusz; Błocki, Narcyz; Daszkiewicz, Marek

2017-10-01

Revolutionary progress in the photonic technology provides the ability to develop military systems of new properties not possible to obtain with the use of classical technologies. In recent years, this progress has resulted in developing advanced, complex, multifunctional and relatively cheap Photonic Integrated Circuits (PIC) or Hybrid Photonics Circuits (HPC) built of a collection of standardized optical, optoelectronic and photonic components. This idea is similar to the technology of Electronic Integrated Circuits, which has revolutionized the microelectronic market. The novel approach to photonic technology is now revolutionizing the photonics' market. It simplifies the photonics technology and enables creation of technological centers for designing, development and production of advanced optical and photonic systems in the EU and other countries. This paper presents some selected photonic technologies and their impact on such defense systems like radars, radiolocation, telecommunication, and radio-communication systems.

NASA N+3 Subsonic Fixed Wing Silent Efficient Low-Emissions Commercial Transport (SELECT) Vehicle Study. Revision A

NASA Technical Reports Server (NTRS)

Bruner, Sam; Baber, Scott; Harris,Chris; Caldwell, Nicholas; Keding, Peter; Rahrig, Kyle; Pho, Luck; Wlezian, Richard

2010-01-01

A conceptual commercial passenger transport study was performed to define a single vehicle for entry into service in the 2030 to 2035 timeframe, meeting customer demands as well as NASA goals for improved fuel economy, NOx emissions, noise, and operability into smaller airports. A study of future market and operational scenarios was used to guide the design of an advanced tube-and-wing configuration that utilized advanced material and structural concepts, an advanced three-shaft high-bypass turbofan engine, natural laminar flow technology, and a suite of other advanced technologies. This configuration was found to meet the goals for NOx emissions, noise, and field length. A 64 percent improvement in fuel economy compared to a current state-of-the-art airliner was achieved, which fell slightly short of the desired 70 percent goal. Technology maturation plans for the technologies used in the design were developed to help guide future research and development activities.

Structures and Materials Working Group report

NASA Technical Reports Server (NTRS)

Torczyner, Robert; Hanks, Brantley R.

1986-01-01

The appropriateness of the selection of four issues (advanced materials development, analysis/design methods, tests of large flexible structures, and structural concepts) was evaluated. A cross-check of the issues and their relationship to the technology drivers is presented. Although all of the issues addressed numerous drivers, the advanced materials development issue impacts six out of the seven drivers and is considered to be the most crucial. The advanced materials technology development and the advanced design/analysis methods development were determined to be enabling technologies with the testing issues and development of structural concepts considered to be of great importance, although not enabling technologies. In addition, and of more general interest and criticality, the need for a Government/Industry commitment which does not now exist, was established. This commitment would call for the establishment of the required infrastructure to facilitate the development of the capabilities highlighted through the availability of resources and testbed facilities, including a national testbed in space to be in place in ten years.

Enabling Laser and Lidar Technologies for NASA's Science and Exploration Mission's Applications

NASA Technical Reports Server (NTRS)

Singh, Upendra N.; Kavaya, Michael J.

2005-01-01

NASA s Laser Risk Reduction Program, begun in 2002, has achieved many technology advances in only 3.5 years. The recent selection of several lidar proposals for Science and Exploration applications indicates that the LRRP goal of enabling future space-based missions by lowering the technology risk has already begun to be met.

A Selective Bibliography of Handbooks and Textbooks on Metalworking and Plastics Working for the Theatre Scene Shop

ERIC Educational Resources Information Center

Van Brunt, Thomas

1975-01-01

Lists books into general categories of those useful for advanced technicians, and those useful for the hobbiest or sculptor-painter. Available from: Theatre Design and Technology, Journal of the U.S. Institute for Theatre Technology, 1 Hillside Road, Newark, Delaware 19711. Subscriptions: subscription to Theatre Design and Technology is a…

Technology and the Polity. Harvard University Program on Technology and Society; Research Review Number Four.

ERIC Educational Resources Information Center

Taviss, Irene, Ed.; Burbank, Judith, Ed.

A small number of selected books and articles which deal with the impact of technological advancement on the American political structure have been abstracted for this document. Materials were chosen for abstracting which presented a significant analysis of issues, a useful compilation of data, or which are representative of different outlooks and…

NASA EEE Parts and Advanced Interconnect Program (AIP)

NASA Technical Reports Server (NTRS)

Gindorf, T.; Garrison, A.

1996-01-01

none given From Program Objectives: I. Accelerate the readiness of new technologies through development of validation, assessment and test method/tools II. Provide NASA Projects infusion paths for emerging technologies III. Provide NASA Projects technology selection, application and validation guidelines for harware and processes IV. Disseminate quality assurance, reliability, validation, tools and availability information to the NASA community.

15 CFR 295.4 - The selection process.

Code of Federal Regulations, 2014 CFR

2014-01-01

... OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY.... NIST will also examine proposals that have been submitted to a previous competition to determine... review of their proposals with NIST, and in some cases site visits may be required. Subject to the...

15 CFR 295.4 - The selection process.

Code of Federal Regulations, 2012 CFR

2012-01-01

... OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY.... NIST will also examine proposals that have been submitted to a previous competition to determine... review of their proposals with NIST, and in some cases site visits may be required. Subject to the...

15 CFR 295.4 - The selection process.

Code of Federal Regulations, 2013 CFR

2013-01-01

... OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY.... NIST will also examine proposals that have been submitted to a previous competition to determine... review of their proposals with NIST, and in some cases site visits may be required. Subject to the...

15 CFR 295.4 - The selection process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY.... NIST will also examine proposals that have been submitted to a previous competition to determine... review of their proposals with NIST, and in some cases site visits may be required. Subject to the...

15 CFR 295.4 - The selection process.

Code of Federal Regulations, 2011 CFR

2011-01-01

... OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL PROGRAMS ADVANCED TECHNOLOGY.... NIST will also examine proposals that have been submitted to a previous competition to determine... review of their proposals with NIST, and in some cases site visits may be required. Subject to the...

Composite fuselage crown panel manufacturing technology

NASA Technical Reports Server (NTRS)

Willden, Kurtis; Metschan, S.; Grant, C.; Brown, T.

1992-01-01

Commercial fuselage structures contain significant challenges in attempting to save manufacturing costs with advanced composite technology. Assembly issues, materials costs, and fabrication of elements with complex geometry are each expected to drive the cost of composite fuselage structure. Key technologies, such as large crown panel fabrication, were pursued for low cost. An intricate bond panel design and manufacturing concept were selected based on the efforts of the Design Build Team. The manufacturing processes selected for the intricate bond design include multiple large panel fabrication with Advanced Tow Placement (ATP) process, innovative cure tooling concepts, resin transfer molding of long fuselage frames, and use of low cost materials forms. The process optimization for final design/manufacturing configuration included factory simulations and hardware demonstrations. These efforts and other optimization tasks were instrumental in reducing costs by 18 pct. and weight by 45 pct. relative to an aluminum baseline. The qualitative and quantitative results of the manufacturing demonstrations were used to assess manufacturing risks and technology readiness.

Composite fuselage crown panel manufacturing technology

NASA Technical Reports Server (NTRS)

Willden, Kurtis; Metschan, S.; Grant, C.; Brown, T.

1992-01-01

Commercial fuselage structures contain significant challenges in attempting to save manufacturing costs with advanced composite technology. Assembly issues, material costs, and fabrication of elements with complex geometry are each expected to drive the cost of composite fuselage structures. Boeing's efforts under the NASA ACT program have pursued key technologies for low-cost, large crown panel fabrication. An intricate bond panel design and manufacturing concepts were selected based on the efforts of the Design Build Team (DBT). The manufacturing processes selected for the intricate bond design include multiple large panel fabrication with the Advanced Tow Placement (ATP) process, innovative cure tooling concepts, resin transfer molding of long fuselage frames, and utilization of low-cost material forms. The process optimization for final design/manufacturing configuration included factory simulations and hardware demonstrations. These efforts and other optimization tasks were instrumental in reducing cost by 18 percent and weight by 45 percent relative to an aluminum baseline. The qualitative and quantitative results of the manufacturing demonstrations were used to assess manufacturing risks and technology readiness.

Advanced aerodynamics. Selected NASA research

NASA Technical Reports Server (NTRS)

1981-01-01

This Conference Publication contains selected NASA papers that were presented at the Fifth Annual Status Review of the NASA Aircraft Energy Efficiency (ACEE) Energy Efficient Transport (EET) Program held at Dryden Flight Research Center in Edwards, California on September 14 to 15, 1981. These papers describe the status of several NASA in-house research activities in the areas of advanced turboprops, natural laminar flow, oscillating control surfaces, high-Reynolds-number airfoil tests, high-lift technology, and theoretical design techniques.

Magnetic liquefier for hydrogen

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1992-12-31

This document summarizes work done at the Astronautics Technology Center of the Astronautics Corporation of America (ACA) in Phase 1 of a four phase program leading to the development of a magnetic liquefier for hydrogen. The project involves the design, fabrication, installation, and operation of a hydrogen liquefier providing significantly reduced capital and operating costs, compared to present liquefiers. To achieve this goal, magnetic refrigeration, a recently developed, highly efficient refrigeration technology, will be used for the liquefaction process. Phase 1 project tasks included liquefier conceptual design and analysis, preliminary design of promising configurations, design selection, and detailed design ofmore » the selected design. Fabrication drawings and vendor specifications for the selected design were completed during detailed design. The design of a subscale, demonstration magnetic hydrogen liquefier represents a significant advance in liquefaction technology. The cost reductions that can be realized in hydrogen liquefaction in both the subscale and, more importantly, in the full-scale device are expected to have considerable impact on the use of liquid hydrogen in transportation, chemical, and electronic industries. The benefits to the nation from this technological advance will continue to have importance well into the 21st century.« less

48 CFR 1852.219-81 - Limitation on subcontracting-SBIR Phase II program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... must be approved in advance and in writing by the Contracting Officer. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval...

48 CFR 1852.219-81 - Limitation on subcontracting-SBIR Phase II program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... must be approved in advance and in writing by the Contracting Officer. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval...

Conceptual design study of advanced acoustic composite nacelle. [for achieving reductions in community noise and operating expense

NASA Technical Reports Server (NTRS)

Goodall, R. G.; Painter, G. W.

1975-01-01

Conceptual nacelle designs for wide-bodied and for advanced-technology transports were studied with the objective of achieving significant reductions in community noise with minimum penalties in airplane weight, cost, and in operating expense by the application of advanced composite materials to nacelle structure and sound suppression elements. Nacelle concepts using advanced liners, annular splitters, radial splitters, translating centerbody inlets, and mixed-flow nozzles were evaluated and a preferred concept selected. A preliminary design study of the selected concept, a mixed flow nacelle with extended inlet and no splitters, was conducted and the effects on noise, direct operating cost, and return on investment determined.

Documenting helicopter operations from an energy standpoint

NASA Technical Reports Server (NTRS)

Davis, S. J.; Stepniewski, W. Z.

1974-01-01

Results are presented of a study of the relative and absolute energy consumption of helicopters, including limited comparisons with fixed-wing aircraft, and selected surface transportation vehicles. Additional comparisons were made to determine the level of reduction in energy consumption expected from the application of advanced technologies to the helicopter design and sizing process. It was found that improvements in helicopter consumption characteristics can be accomplished through the utilization of advanced technology to reduce drag, structures weight, and powerplant fuel consumption.

Diagnostic Molecular Microbiology: A 2018 Snapshot.

PubMed

Fairfax, Marilynn Ransom; Bluth, Martin H; Salimnia, Hossein

2018-06-01

Molecular biological techniques have evolved expeditiously and in turn have been applied to the detection of infectious disease. Maturation of these technologies and their coupling with related technological advancement in fluorescence, electronics, digitization, nanodynamics, and sensors among others have afforded clinical medicine additional tools toward expedient identification of infectious organisms at concentrations and sensitivities previously unattainable. These advancements have been adapted in select settings toward addressing clinical demands for more timely and effective patient management. Copyright © 2018 Elsevier Inc. All rights reserved.

Study on utilization of advanced composites in fuselage structures of large transports

NASA Technical Reports Server (NTRS)

Johnson, R. W.; Thomson, L. W.; Wilson, R. D.

1985-01-01

The potential for utilizing advanced composites in fuselage structures of large transports was assessed. Six fuselage design concepts were selected and evaluated in terms of structural performance, weight, and manufacturing development and costs. Two concepts were selected that merit further consideration for composite fuselage application. These concepts are: (1) a full depth honeycomb design with no stringers, and (2) an I section stringer stiffened laminate skin design. Weight reductions due to applying composites to the fuselages of commercial and military transports were calculated. The benefits of applying composites to a fleet of military transports were determined. Significant technology issues pertinent to composite fuselage structures were identified and evaluated. Program plans for resolving the technology issues were developed.

T/BEST: Technology Benefit Estimator for Composites and Applications to Engine Structures

NASA Technical Reports Server (NTRS)

Chamis, Christos

1997-01-01

Progress in the field of aerospace propulsion has heightened the need to combine advanced technologies. These benefits will provide guidelines for identifying and prioritizing high-payoff research areas, will help manage research with limited resources, and will show the link between advanced and basic concepts. An effort was undertaken at the NASA Lewis Research Center to develop a formal computational method, T/BEST (Technology Benefit Estimator), to assess advanced aerospace technologies, such as fibrous composites, and credibly communicate the benefits of research. Fibrous composites are ideal for structural applications such as high-performance aircraft engine blades where high strength-to-weight and stiffness-to-weight ratios are required. These factors - along with the flexibility to select the composite system and layup, and to favorably orient fiber directions - reduce the displacements and stresses caused by large rotational speeds in aircraft engines.

Elderly people's interaction with advanced technology.

PubMed

Blažun, Helena; Vošner, Janez; Kokol, Peter; Saranto, Kaija; Rissanen, Sari

2014-01-01

Aging of population is an inevitable process by which the number of elderly people is increasing. Rapid development of information and communication technology (ICT) is changing basic needs of elderly people; therefore society should ensure opportunities for elderly to learn and use ICT in a way to manage their daily life activities and in this way enable them participation in the information and knowledge society. The purpose of the study was to find out whether elderly are acquainted with the advanced technology and to what extent they use it or they desire to use it. Within the single point study we interviewed 100 randomly selected elderly people from different geographical regions in Slovenia. Results showed the differences in the use of advanced technology by Slovenian regions; therefore in the future activities should be focused on organizing promotional and demonstrational activities including ICT courses to increase elderly's motivation for ICT interaction.

Advanced Life Support Research and Technology Development Metric

NASA Technical Reports Server (NTRS)

Hanford, A. J.

2004-01-01

The Metric is one of several measures employed by the NASA to assess the Agency s progress as mandated by the United States Congress and the Office of Management and Budget. Because any measure must have a reference point, whether explicitly defined or implied, the Metric is a comparison between a selected ALS Project life support system and an equivalently detailed life support system using technology from the Environmental Control and Life Support System (ECLSS) for the International Space Station (ISS). This document provides the official calculation of the Advanced Life Support (ALS) Research and Technology Development Metric (the Metric) for Fiscal Year 2004. The values are primarily based on Systems Integration, Modeling, and Analysis (SIMA) Element approved software tools or reviewed and approved reference documents. For Fiscal Year 2004, the Advanced Life Support Research and Technology Development Metric value is 2.03 for an Orbiting Research Facility and 1.62 for an Independent Exploration Mission.

Advanced Rotorcraft Transmission (ART) program summary

NASA Technical Reports Server (NTRS)

Krantz, T. L.; Kish, J. G.

1992-01-01

The Advanced Rotorcraft Transmission (ART) Program was initiated to advance the state of the art for rotorcraft transmissions. The goal of the ART Program was to develop and demonstrate the technologies needed to reduce transmission weight by 25 pct. and reduce noise by 10 dB while obtaining a 5000 hr 'mean time between failure'. The research done under the ART Program is summarized. A split path design was selected as best able to meet the program goals. Key part technologies needed for this design were identified, studied, and developed. Two of these technologies are discussed in detail: the load sharing of split path designs including the use of a compliant elastomeric torque splitter and the application of a high ratio, low pitch line velocity gear mesh. Development of an angular contact spherical roller bearing, transmission error analysis, and fretting fatigue testing are discussed. The technologies for a light weight, quiet, and reliable rotorcraft transmission were demonstrated.

Advanced technology commercial fuselage structure

NASA Technical Reports Server (NTRS)

Ilcewicz, L. B.; Smith, P. J.; Walker, T. H.; Johnson, R. W.

1991-01-01

Boeing's program for Advanced Technology Composite Aircraft Structure (ATCAS) has focused on the manufacturing and performance issues associated with a wide body commercial transport fuselage. The primary goal of ATCAS is to demonstrate cost and weight savings over a 1995 aluminum benchmark. A 31 foot section of fuselage directly behind the wing to body intersection was selected for study purposes. This paper summarizes ATCAS contract plans and review progress to date. The six year ATCAS program will study technical issues for crown, side, and keel areas of the fuselage. All structural details in these areas will be included in design studies that incorporate a design build team (DBT) approach. Manufacturing technologies will be developed for concepts deemed by the DBT to have the greatest potential for cost and weight savings. Assembly issues for large, stiff, quadrant panels will receive special attention. Supporting technologies and mechanical tests will concentrate on the major issues identified for fuselage. These include damage tolerance, pressure containment, splices, load redistribution, post-buckled structure, and durability/life. Progress to date includes DBT selection of baseline fuselage concepts; cost and weight comparisons for crown panel designs; initial panel fabrication for manufacturing and structural mechanics research; and toughened material studies related to keel panels. Initial ATCAS studies have shown that NASA's Advanced Composite Technology program goals for cost and weight savings are attainable for composite fuselage.

Innovations for Federal Service: A Study of Innovative Technologies for Federal Government Services to Older Americans and Consumers. Final Report.

ERIC Educational Resources Information Center

Harris, John; And Others

This document focuses on technologies that can be used to improve federal government services. Reference Point, a foundation based in New Jersey, was chosen by the Office of Technology Assessment of the U.S. Congress to study the application of advanced information. The applications selected for the study were: Electronic Information…

SCARLET Photovoltaic Concentrator Array Selected for Flight Under NASA's New Millennium Program

NASA Technical Reports Server (NTRS)

Piszczor, Michael F., Jr.

1997-01-01

The NASA Lewis Research Center continues to demonstrate its expertise in the development and implementation of advanced space power systems. For example, during the past year, the NASA New Millennium Program selected the Solar Concentrator Array with Refractive Linear Element Technology (SCARLET) photovoltaic array as the power system for its Deep Space-1 (DS-1) mission. This Jet Propulsion Laboratory (JPL) managed DS-1 mission, which represents the first operational flight of a photovoltaic concentrator array, will provide a baseline for the use of this technology in a variety of future government and commercial applications. SCARLET is a joint NASA Lewis/Ballistic Missile Defense Organization program to develop advanced photovoltaic array technology that uses a unique refractive concentrator design to focus sunlight onto a line of photovoltaic cells located below the optical element. The general concept is based on previous work conducted at Lewis under a Small Business Innovation Research (SBIR) contract with AEC-Able Engineering, Inc., for the Multiple Experiments to Earth Orbit and Return (METEOR) spacecraft. The SCARLET II design selected by the New Millennium Program is a direct adaptation of the smaller SCARLET I array built for METEOR. Even though SCARLET I was lost during a launch failure in October 1995, the hardware (designed, built, and flight qualified within 6 months) provided invaluable information and experience that led to the selection of this technology as the primary power source for DS-1.

A group decision-making tool for the application of membrane technologies in different water reuse scenarios.

PubMed

Sadr, S M K; Saroj, D P; Kouchaki, S; Ilemobade, A A; Ouki, S K

2015-06-01

A global challenge of increasing concern is diminishing fresh water resources. A growing practice in many communities to supplement diminishing fresh water availability has been the reuse of water. Novel methods of treating polluted waters, such as membrane assisted technologies, have recently been developed and successfully implemented in many places. Given the diversity of membrane assisted technologies available, the current challenge is how to select a reliable alternative among numerous technologies for appropriate water reuse. In this research, a fuzzy logic based multi-criteria, group decision making tool has been developed. This tool has been employed in the selection of appropriate membrane treatment technologies for several non-potable and potable reuse scenarios. Robust criteria, covering technical, environmental, economic and socio-cultural aspects, were selected, while 10 different membrane assisted technologies were assessed in the tool. The results show this approach capable of facilitating systematic and rigorous analysis in the comparison and selection of membrane assisted technologies for advanced wastewater treatment and reuse. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Impact of Technology on Superintendent Communication

ERIC Educational Resources Information Center

Kelly, Victoria L.

2009-01-01

Technological advances have revolutionized the communication patterns and behaviors of district leaders. In this information-based society, the ability of the leader to select the form of communication most appropriate to the context and situation qualifies his or her effectiveness at communication. The findings emerging from this study highlight…

Review of storage battery system cost estimates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, D.R.; Russell, J.A.

1986-04-01

Cost analyses for zinc bromine, sodium sulfur, and lead acid batteries were reviewed. Zinc bromine and sodium sulfur batteries were selected because of their advanced design nature and the high level of interest in these two technologies. Lead acid batteries were included to establish a baseline representative of a more mature technology.

Military aircraft and missile technology at the Langley Research Center: A selected bibliography

NASA Technical Reports Server (NTRS)

Maddalon, D. V.

1980-01-01

A compilation of reference material is presented on the Langley Research Center's efforts in developing advanced military aircraft and missile technology over the past twenty years. Reference material includes research made in aerodynamics, performance, stability, control, stall-spin, propulsion integration, flutter, materials, and structures.

Characterization of alternative electric generation technologies for the SPS comparative assessment. Volume 1: Summary of central station technologies

NASA Astrophysics Data System (ADS)

1980-08-01

The technologies selected for the detailed characterization were: solar technology; terrestrial photovoltaic (200 MWe); coal technologies; conventional high sulfur coal combustion with advanced fine gas desulfurization (1250 MWe), and open cycle gas turbine combined cycle plant with low Btu gasifier (1250 MWe); and nuclear technologies: conventional light water reactor (1250 MWe), liquid metal fast breeder reactor (1250 MWe), and magnetic fusion reactor (1320 MWe). A brief technical summary of each power plant design is given.

Overview study of Space Power Technologies for the advanced energetics program. [spacecraft

NASA Technical Reports Server (NTRS)

Taussig, R.; Gross, S.; Millner, A.; Neugebauer, M.; Phillips, W.; Powell, J.; Schmidt, E.; Wolf, M.; Woodcock, G.

1981-01-01

Space power technologies are reviewed to determine the state-of-the-art and to identify advanced or novel concepts which promise large increases in performance. The potential for incresed performance is judged relative to benchmarks based on technologies which have been flight tested. Space power technology concepts selected for their potentially high performance are prioritized in a list of R & D topical recommendations for the NASA program on Advanced Energetics. The technology categories studied are solar collection, nuclear power sources, energy conversion, energy storage, power transmission, and power processing. The emphasis is on electric power generation in space for satellite on board electric power, for electric propulsion, or for beamed power to spacecraft. Generic mission categories such as low Earth orbit missions and geosynchronous orbit missions are used to distinguish general requirements placed on the performance of power conversion technology. Each space power technology is judged on its own merits without reference to specific missions or power systems. Recommendations include 31 space power concepts which span the entire collection of technology categories studied and represent the critical technologies needed for higher power, lighter weight, more efficient power conversion in space.

Regenerative fuel cell systems for space station

NASA Technical Reports Server (NTRS)

Hoberecht, M. A.; Sheibley, D. W.

1985-01-01

Regenerative fuel cell (RFC) systems are the leading energy storage candidates for Space Station. Key design features are the advanced state of technology readiness and high degree of system level design flexibility. Technology readiness was demonstrated through testing at the single cell, cell stack, mechanical ancillary component, subsystem, and breadboard levels. Design flexibility characteristics include independent sizing of power and energy storage portions of the system, integration of common reactants with other space station systems, and a wide range of various maintenance approaches. The design features led to selection of a RFC system as the sole electrochemical energy storage technology option for the space station advanced development program.

Spacecraft Impacts with Advanced Power and Electric Propulsion

NASA Technical Reports Server (NTRS)

Mason, Lee S.; Oleson, Steven R.

2000-01-01

A study was performed to assess the benefits of advanced power and electric propulsion systems for various space missions. Advanced power technologies that were considered included multiband gap and thin-film solar arrays, lithium batteries, and flywheels. Electric propulsion options included Hall effect thrusters and Ion thrusters. Several mission case studies were selected as representative of future applications for advanced power and propulsion systems. These included a low altitude Earth science satellite, a LEO communications constellation, a GEO military surveillance satellite, and a Mercury planetary mission. The study process entailed identification of overall mission performance using state-of-the-art power and propulsion technology, enhancements made possible with either power or electric propulsion advances individually, and the collective benefits realized when advanced power and electric propulsion are combined. Impacts to the overall spacecraft included increased payload, longer operational life, expanded operations and launch vehicle class step-downs.

Aero-Propulsion Technology (APT) Task V Low Noise ADP Engine Definition Study

NASA Technical Reports Server (NTRS)

Holcombe, V.

2003-01-01

A study was conducted to identify and evaluate noise reduction technologies for advanced ducted prop propulsion systems that would allow increased capacity operation and result in an economically competitive commercial transport. The study investigated the aero/acoustic/structural advancements in fan and nacelle technology required to match or exceed the fuel burned and economic benefits of a constrained diameter large Advanced Ducted Propeller (ADP) compared to an unconstrained ADP propulsion system with a noise goal of 5 to 10 EPNDB reduction relative to FAR 36 Stage 3 at each of the three measuring stations namely, takeoff (cutback), approach and sideline. A second generation ADP was selected to operate within the maximum nacelle diameter constrain of 160 deg to allow installation under the wing. The impact of fan and nacelle technologies of the second generation ADP on fuel burn and direct operating costs for a typical 3000 nm mission was evaluated through use of a large, twin engine commercial airplane simulation model. The major emphasis of this study focused on fan blade aero/acoustic and structural technology evaluations and advanced nacelle designs. Results of this study have identified the testing required to verify the interactive performance of these components, along with noise characteristics, by wind tunnel testing utilizing and advanced interaction rig.

Advanced Launch Technology Life Cycle Analysis Using the Architectural Comparison Tool (ACT)

NASA Technical Reports Server (NTRS)

McCleskey, Carey M.

2015-01-01

Life cycle technology impact comparisons for nanolauncher technology concepts were performed using an Affordability Comparison Tool (ACT) prototype. Examined are cost drivers and whether technology investments can dramatically affect the life cycle characteristics. Primary among the selected applications was the prospect of improving nanolauncher systems. As a result, findings and conclusions are documented for ways of creating more productive and affordable nanolauncher systems; e.g., an Express Lane-Flex Lane concept is forwarded, and the beneficial effect of incorporating advanced integrated avionics is explored. Also, a Functional Systems Breakdown Structure (F-SBS) was developed to derive consistent definitions of the flight and ground systems for both system performance and life cycle analysis. Further, a comprehensive catalog of ground segment functions was created.

Technological advances in the surgical treatment of movement disorders.

PubMed

Gross, Robert E; McDougal, Margaret E

2013-08-01

Technological innovations have driven the advancement of the surgical treatment of movement disorders, from the invention of the stereotactic frame to the adaptation of deep brain stimulation (DBS). Along these lines, this review will describe recent advances in inserting neuromodulation modalities, including DBS, to the target, and in the delivery of therapy at the target. Recent radiological advances are altering the way that DBS leads are targeted and inserted, by refining the ability to visualize the subcortical targets using high-field strength magnetic resonance imaging and other innovations, such as diffusion tensor imaging, and the development of novel targeting devices enabling purely anatomical implantations without the need for neurophysiological monitoring. New portable computed tomography scanners also are facilitating lead implantation without monitoring, as well as improving radiological verification of DBS lead location. Advances in neurophysiological mapping include efforts to develop automatic target verification algorithms, and probabilistic maps to guide target selection. The delivery of therapy at the target is being improved by the development of the next generation of internal pulse generators (IPGs). These include constant current devices that mitigate the variability introduced by impedance changes of the stimulated tissue and, in the near future, devices that deliver novel stimulation patterns with improved efficiency. Closed-loop adaptive IPGs are being tested, which may tailor stimulation to ongoing changes in the nervous system, reflected in biomarkers continuously recorded by the devices. Finer-grained DBS leads, in conjunction with new IPGs and advanced programming tools, may offer improved outcomes via current steering algorithms. Finally, even thermocoagulation-essentially replaced by DBS-is being advanced by new minimally-invasive approaches that may improve this therapy for selected patients in whom it may be preferred. Functional neurosurgery has a history of being driven by technological innovation, a tradition that continues into its future.

Cogeneration technology alternatives study. Volume 1: Summary report

NASA Technical Reports Server (NTRS)

1980-01-01

Data and information in the area of advanced energy conversion systems for industrial congeneration applications in the 1985-2000 time period was studied. Six current and thirty-one advanced energy conversion systems were defined and combined with appropriate balance-of-plant equipment. Twenty-six industrial processes were selected from among the high energy consuming industries to serve as a framework for the study. Each conversion system was analyzed as a cogenerator with each industrial plant. Fuel consumption, costs, and environmental intrusion were evaluated and compared to corresponding traditional values. Various cogeneration strategies were analyzed and both topping and bottoming (using industrial by-product heat) applications were included. The advanced energy conversion technologies indicated reduced fuel consumption, costs, and emissions. Typically fuel energy savings of 10 to 25 percent were predicted compared to traditional on-site furnaces and utility electricity. With the variety of industrial requirements, each advanced technology had attractive applications. Overall, fuel cells indicated the greatest fuel energy savings and emission reductions. Gas turbines and combined cycles indicated high overall annual cost savings. Steam turbines and gas turbines produced high estimated returns. In some applications, diesels were most efficient. The advanced technologies used coal-derived fuels, or coal with advanced fluid bed combustion or on-site gasification systems.

Design approaches to more energy efficient engines

NASA Technical Reports Server (NTRS)

Saunders, N. T.; Colladay, R. S.; Macioce, L. E.

1978-01-01

The status of NASA's Energy Efficient Engine Project, a comparative government-industry effort aimed at advancing the technology base for the next generation of large turbofan engines for civil aircraft transports is summarized. Results of recently completed studies are reviewed. These studies involved selection of engine cycles and configurations that offer potential for at least 12% lower fuel consumption than current engines and also are economically attractive and environmentally acceptable. Emphasis is on the advancements required in component technologies and systems design concepts to permit future development of these more energy efficient engines.

CRISPR-based technologies for the manipulation of eukaryotic genomes

PubMed Central

Komor, Alexis C.; Badran, Ahmed H.; Liu, David R.

2016-01-01

The CRISPR-Cas9 RNA-guided DNA endonuclease has contributed to an explosion of advances in the life sciences that have grown from the ability to edit genomes within living cells. In this review we summarize CRISPR-based technologies that enable mammalian genome editing and their various applications. We describe recent developments that extend the generality, DNA specificity, product selectivity, and fundamental capabilities of natural CRISPR systems, and some of the remarkable advancements in basic research, biotechnology, and therapeutics development that these developments have facilitated. PMID:27866654

Textile technology development

NASA Technical Reports Server (NTRS)

Shah, Bharat M.

1995-01-01

The objectives of this report were to evaluate and select resin systems for Resin Transfer Molding (RTM) and Powder Towpreg Material, to develop and evaluate advanced textile processes by comparing 2-D and 3-D braiding for fuselage frame applications and develop window belt and side panel structural design concepts, to evaluate textile material properties, and to develop low cost manufacturing and tooling processes for the automated manufacturing of fuselage primary structures. This research was in support of the NASA and Langley Research Center (LaRc) Advanced Composite Structural Concepts and Materials Technologies for Primary Aircraft Structures program.

The Advanced Communications Technology Satellite (ACTS) capabilities for serving science

NASA Technical Reports Server (NTRS)

Meyer, Thomas R.

1990-01-01

Results of research on potential science applications of the NASA Advanced Communications Technology Satellite (ACTS) are presented. Discussed here are: (1) general research on communications related issues; (2) a survey of science-related activities and programs in the local area; (3) interviews of selected scientists and associated telecommunications support personnel whose projects have communications requirements; (4) analysis of linkages between ACTS functionality and science user communications activities and modes of operation; and (5) an analysis of survey results and the projection of conclusions to a national scale.

Study of structural design concepts for an arrow wing supersonic transport configuration, volume 1. Tasks 1 and 2

NASA Technical Reports Server (NTRS)

1976-01-01

A structural design study was made, based on a 1975 level of technology, to assess the relative merits of structural concepts and materials for an advanced supersonic transport cruising at Mach 2.7. Preliminary studies were made to insure compliance of the configuration with general design criteria, to integrate the propulsion system with the airframe, to select structural concepts and materials, and to define an efficient structural arrangement. An advanced computerized structural design system was used, in conjunction with a relatively large, complex finite element model, for detailed analysis and sizing of structural members to satisfy strength and flutter criteria. A baseline aircraft design was developed for assessment of current technology and for use in future studies of aerostructural trades, and application of advanced technology. Criteria, analysis methods, and results are presented.

A technology selection framework for supporting delivery of patient-oriented health interventions in developing countries

PubMed Central

Chan, Connie V.; Kaufman, David R.

2009-01-01

Health information technologies (HIT) have great potential to advance health care globally. In particular, HIT can provide innovative approaches and methodologies to overcome the range of access and resource barriers specific to developing countries. However, there is a paucity of models and empirical evidence informing the technology selection process in these settings. We propose a framework for selecting patient-oriented technologies in developing countries. The selection guidance process is structured by a set of filters that impose particular constraints and serve to narrow the space of possible decisions. The framework consists of three levels of factors: 1) situational factors, 2) the technology and its relationship with health interventions and with target patients, and 3) empirical evidence. We demonstrate the utility of the framework in the context of mobile phones for behavioral health interventions to reduce risk factors for cardiovascular disease. This framework can be applied to health interventions across health domains to explore how and whether available technologies can support delivery of the associated types of interventions and with the target populations. PMID:19796709

Solar Innovator | Alta Devices

ScienceCinema

Mattos, Laila; Le, Minh

2017-12-09

Selected to participate in the Energy Department's SunShot Initiative, Alta Devices produces solar cells that convert sunlight into electricity at world record-breaking levels of efficiency. Through its innovative solar technology Alta is helping bring down the cost of solar. Learn more about the Energy Department's efforts to advance solar technology at energy.gov/solar .

Selected Papers from the National Conference on College Teaching and Learning (4th, Jacksonville, Florida, April 14-17, 1993).

ERIC Educational Resources Information Center

Chambers, Jack A., Ed.

This collection of 18 papers covers four broad areas of teaching and learning in higher education: innovative college teaching/learning strategies; effective classroom research/assessment activities; advanced classroom technology; and developing teaching and learning centers. Titles include: (1) "Changing Teaching Styles When Technology Becomes…

Advanced Propulsion System Studies for General Aviation Aircraft

NASA Technical Reports Server (NTRS)

Eisenberg, Joseph D. (Technical Monitor); German, Jon

2003-01-01

This final report addresses the following topics: Market Impact Analysis (1) assessment of general aviation, including commuter/regional, aircraft market impact due to incorporation of advanced technology propulsion system on acquisition and operating costs, job creation and/or manpower demand, and future fleet size; (2) selecting an aircraft and engine for the study by focusing on the next generation 19-passenger commuter and the Williams International FJ44 turbofan engine growth. Propulsion System Analysis Conducted mission analysis studies and engine cycle analysis to define a new commuter mission and required engine performance, define acquisition and operating costs and, select engine configuration and initiated preliminary design for hardware modifications required. Propulsion System Benefits (1) assessed and defined engine emissions improvements, (2) assessed and defined noise reduction potential and, (3) conducted a cost analysis impact study. Review of Relevant NASA Programs Conducted literature searches using NERAC and NASA RECON services for related technology in the emissions and acoustics area. Preliminary Technology Development Plans Defined plan to incorporate technology improvements for an FJ44-2 growth engine in performance, emissions, and noise suppression.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study, volume 1

NASA Technical Reports Server (NTRS)

Hanks, G. W.; Shomber, H. A.; Dethman, H. A.; Gratzer, L. B.; Maeshiro, A.; Gangsaas, D.; Blight, J. D.; Buchan, S. M.; Crumb, C. B.; Dorwart, R. J.

1981-01-01

An active controls technology (ACT) system architecture was selected based on current technology system elements and optimal control theory was evaluated for use in analyzing and synthesizing ACT multiple control laws. The system selected employs three redundant computers to implement all of the ACT functions, four redundant smaller computers to implement the crucial pitch-augmented stability function, and a separate maintenance and display computer. The reliability objective of probability of crucial function failure of less than 1 x 10 to the -9th power per flight of 1 hr can be met with current technology system components, if the software is assumed fault free and coverage approaching 1.0 can be provided. The optimal control theory approach to ACT control law synthesis yielded comparable control law performance much more systematically and directly than the classical s-domain approach. The ACT control law performance, although somewhat degraded by the inclusion of representative nonlinearities, remained quite effective. Certain high-frequency gust-load alleviation functions may require increased surface rate capability.

Advanced Natural Gas Reciprocating Engine(s)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pike, Edward

The objective of the Cummins ARES program, in partnership with the US Department of Energy (DOE), is to develop advanced natural gas engine technologies that increase engine system efficiency at lower emissions levels while attaining lower cost of ownership. The goals of the project are to demonstrate engine system achieving 50% Brake Thermal Efficiency (BTE) in three phases, 44%, 47% and 50% (starting baseline efficiency at 36% BTE) and 0.1 g/bhp-hr NOx system out emissions (starting baseline NOx emissions at 2 – 4 g/bhp-hr NOx). Primary path towards above goals include high Brake Mean Effective Pressure (BMEP), improved closed cyclemore » efficiency, increased air handling efficiency and optimized engine subsystems. Cummins has successfully demonstrated each of the phases of this program. All targets have been achieved through application of a combined set of advanced base engine technologies and Waste Heat Recovery from Charge Air and Exhaust streams, optimized and validated on the demonstration engine and other large engines. The following architectures were selected for each Phase: Phase 1: Lean Burn Spark Ignited (SI) Key Technologies: High Efficiency Turbocharging, Higher Efficiency Combustion System. In production on the 60/91L engines. Over 500MW of ARES Phase 1 technology has been sold. Phase 2: Lean Burn Technology with Exhaust Waste Heat Recovery (WHR) System Key Technologies: Advanced Ignition System, Combustion Improvement, Integrated Waste Heat Recovery System. Base engine technologies intended for production within 2 to 3 years Phase 3: Lean Burn Technology with Exhaust and Charge Air Waste Heat Recovery System Key Technologies: Lower Friction, New Cylinder Head Designs, Improved Integrated Waste Heat Recovery System. Intended for production within 5 to 6 years Cummins is committed to the launch of next generation of large advanced NG engines based on ARES technology to be commercialized worldwide.« less

Advanced Envelope Research for Factory Built Housing, Phase 3. Design Development and Prototyping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Kessler, B.; Mullens, M.

2014-01-01

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research -- stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Advanced Envelope Research for Factory Built Housing, Phase 3 -- Design Development and Prototyping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, E.; Kessler, B.; Mullens, M.

2014-01-01

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research -- stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Gasification Product Improvement Facility (GPIF). Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

The gasifier selected for development under this contract is an innovative and patented hybrid technology which combines the best features of both fixed-bed and fluidized-bed types. PyGas{trademark}, meaning Pyrolysis Gasification, is well suited for integration into advanced power cycles such as IGCC. It is also well matched to hot gas clean-up technologies currently in development. Unlike other gasification technologies, PyGas can be designed into both large and small scale systems. It is expected that partial repowering with PyGas could be done at a cost of electricity of only 2.78 cents/kWh, more economical than natural gas repowering. It is extremely unfortunatemore » that Government funding for such a noble cause is becoming reduced to the point where current contracts must be canceled. The Gasification Product Improvement Facility (GPIF) project was initiated to provide a test facility to support early commercialization of advanced fixed-bed coal gasification technology at a cost approaching $1,000 per kilowatt for electric power generation applications. The project was to include an innovative, advanced, air-blown, pressurized, fixed-bed, dry-bottom gasifier and a follow-on hot metal oxide gas desulfurization sub-system. To help defray the cost of testing materials, the facility was to be located at a nearby utility coal fired generating site. The patented PyGas{trademark} technology was selected via a competitive bidding process as the candidate which best fit overall DOE objectives. The paper describes the accomplishments to date.« less

Cogeneration Technology Alternatives Study (CTAS) Volume 5: Analytical approach and results

NASA Technical Reports Server (NTRS)

1980-01-01

Data and information in the area of advanced energy conversion systems for industrial cogeneration applications in the 1985 to 2000 time period are provided. Six current and thirty-six advanced energy conversion systems were defined and combined with appropriate balance of plant equipment. Twenty-six industrial processes were selected from among the high energy consuming industries to serve as a framework for the study. Each conversion system was analyzed as a cogenerator with each industrial plant. Fuel consumption, costs, and environmental intrusion were evaluated and compared to corresponding traditional values. Various cogeneration strategies were analyzed and both topping and bottoming (using industrial by-product heat) applications were included. The advanced energy conversion technologies indicated reduced fuel consumption, costs, and emissions. Typically fuel energy savings of 10 to 25 percent were predicted compared to traditional on site furnaces and utility electricity. Gas turbines and combined cycles indicated high overall annual cost savings. Steam turbines and gas turbines produced high estimated returns. In some applications, diesels were most efficient. The advanced technologies used coal derived fuels, or coal with advanced fluid bed combustion or on site gasification systems.

Propulsion Study for Small Transport Aircraft Technology (STAT)

NASA Technical Reports Server (NTRS)

Gill, J. C.; Earle, R. V.; Staton, D. V.; Stolp, P. C.; Huelster, D. S.; Zolezzi, B. A.

1980-01-01

Propulsion requirements were determined for 0.5 and 0.7 Mach aircraft. Sensitivity studies were conducted on both these aircraft to determine parametrically the influence of propulsion characteristics on aircraft size and direct operating cost (DOC). Candidate technology elements and design features were identified and parametric studies conducted to select the STAT advanced engine cycle. Trade off studies were conducted to determine those advanced technologies and design features that would offer a reduction in DOC for operation of the STAT engines. These features were incorporated in the two STAT engines. A benefit assessment was conducted comparing the STAT engines to current technology engines of the same power and to 1985 derivatives of the current technology engines. Research and development programs were recommended as part of an overall technology development plan to ensure that full commercial development of the STAT engines could be initiated in 1988.

Cost/benefit analysis of advanced materials technology candidates for the 1980's, part 2

NASA Technical Reports Server (NTRS)

Dennis, R. E.; Maertins, H. F.

1980-01-01

Cost/benefit analyses to evaluate advanced material technologies projects considered for general aviation and turboprop commuter aircraft through estimated life-cycle costs, direct operating costs, and development costs are discussed. Specifically addressed is the selection of technologies to be evaluated; development of property goals; assessment of candidate technologies on typical engines and aircraft; sensitivity analysis of the changes in property goals on performance and economics, cost, and risk analysis for each technology; and ranking of each technology by relative value. The cost/benefit analysis was applied to a domestic, nonrevenue producing, business-type jet aircraft configured with two TFE731-3 turbofan engines, and to a domestic, nonrevenue producing, business type turboprop aircraft configured with two TPE331-10 turboprop engines. In addition, a cost/benefit analysis was applied to a commercial turboprop aircraft configured with a growth version of the TPE331-10.

State of the Art for Deep Brain Stimulation Therapy in Movement Disorders: A Clinical and Technological Perspective.

PubMed

Wagle Shukla, Aparna; Okun, Michael S

2016-01-01

Deep brain stimulation (DBS) therapy is a widely used brain surgery that can be applied for many neurological and psychiatric disorders. DBS is American Food and Drug Administration approved for medication refractory Parkinson's disease, essential tremor and dystonia. Although DBS has shown consistent success in many clinical trials, the therapy has limitations and there are well-recognized complications. Thus, only carefully selected patients are ideal candidates for this surgery. Over the last two decades, there have been significant advances in clinical knowledge on DBS. In addition, the surgical techniques and technology related to DBS has been rapidly evolving. The goal of this review is to describe the current status of DBS in the context of movement disorders, outline the mechanisms of action for DBS in brief, discuss the standard surgical and imaging techniques, discuss the patient selection and clinical outcomes in each of the movement disorders, and finally, introduce the recent advancements from a clinical and technological perspective.

An Exploratory Analysis for the Selection and Implementation of Advanced Manufacturing Technology by Fuzzy Multi-criteria Decision Making Methods: A Comparative Study

NASA Astrophysics Data System (ADS)

Nath, Surajit; Sarkar, Bijan

2017-08-01

Advanced Manufacturing Technologies (AMTs) offer opportunities for the manufacturing organizations to excel their competitiveness and in turn their effectiveness in manufacturing. Proper selection and evaluation of AMTs is the most significant task in today's modern world. But this involves a lot of uncertainty and vagueness as it requires many conflicting criteria to deal with. So the task of selection and evaluation of AMTs becomes very tedious for the evaluators as they are not able to provide crisp data for the criteria. Different Fuzzy Multi-criteria Decision Making (MCDM) methods help greatly in dealing with this problem. This paper focuses on the application of two very much potential Fuzzy MCDM methods namely COPRAS-G, EVAMIX and a comparative study between them on some rarely mentioned criteria. Each of the two methods is very powerful evaluation tool and has beauty in its own. Although, performance wise these two methods are almost at same level, but, the approach of each one of them are quite unique. This uniqueness is revealed by introducing a numerical example of selection of AMT.

TPS Ablator Technologies for Interplanetary Spacecraft

NASA Technical Reports Server (NTRS)

Curry, Donald M.

2004-01-01

This slide presentation reviews the status of Thermal Protection System (TPS) Ablator technologies and the preparation for use in interplanetary spacecraft. NASA does not have adequate TPS ablatives and sufficient selection for planned missions. It includes a comparison of shuttle and interplanetary TPS requirements, the status of mainline TPS charring ablator materials, a summary of JSC SBIR accomplishments in developing advanced charring ablators and the benefits of SBIR Ablator/fabrication technology.

A Review of Past Insights by Robert Forward and Current Advanced Propulsion Activities

NASA Technical Reports Server (NTRS)

Robertson, Tony; Norley, G. D.

2003-01-01

A review of various technologies discussed by Dr. Robert Forward is done as a tribute to Dr. Forward, and is based on selections from his writings. These speculations and predictions by Dr. Forward are used as a basis for discussing expected propulsion technology work over the next twenty years. Among the technologies to be discussed are antimatter propulsion, space elevators and tethers, and laser propulsion.

Evaluating the Development of Biocatalytic Technology for the Targeted Removal of Perchlorate from Drinking Water.

PubMed

Hutchison, Justin M; Guest, Jeremy S; Zilles, Julie L

2017-06-20

Removing micropollutants is challenging in part because of their toxicity at low concentrations. A biocatalytic approach could harness the high affinity of enzymes for their substrates to address this challenge. The potential of biocatalysis relative to mature (nonselective ion exchange, selective ion exchange, and whole-cell biological reduction) and emerging (catalysis) perchlorate-removal technologies was evaluated through a quantitative sustainable design framework, and research objectives were prioritized to advance economic and environmental sustainability. In its current undeveloped state, the biocatalytic technology was approximately 1 order of magnitude higher in cost and environmental impact than nonselective ion exchange. Biocatalyst production was highly correlated with cost and impact. Realistic improvement scenarios targeting biocatalyst yield, biocatalyst immobilization for reuse, and elimination of an electron shuttle could reduce total costs to $0.034 m -3 and global warming potential (GWP) to 0.051 kg CO 2 eq m -3 : roughly 6.5% of cost and 7.3% of GWP of the background from drinking water treatment and competitive with the best performing technology, selective ion exchange. With less stringent perchlorate regulatory limits, ion exchange technologies had increased cost and impact, in contrast to biocatalytic and catalytic technologies. Targeted advances in biocatalysis could provide affordable and sustainable treatment options to protect the public from micropollutants.

Review of the harvesting and extraction program within the National Alliance for Advanced Biofuels and Bioproducts

DOE PAGES

Marrone, Babetta L.; Lacey, Ronald E.; Anderson, Daniel B.; ...

2017-08-07

Energy-efficient and scalable harvesting and lipid extraction processes must be developed in order for the algal biofuels and bioproducts industry to thrive. The major challenge for harvesting is the handling of large volumes of cultivation water to concentrate low amounts of biomass. For lipid extraction, the major energy and cost drivers are associated with disrupting the algae cell wall and drying the biomass before solvent extraction of the lipids. Here we review the research and development conducted by the Harvesting and Extraction Team during the 3-year National Alliance for Advanced Biofuels and Bioproducts (NAABB) algal consortium project. The harvesting andmore » extraction team investigated five harvesting and three wet extraction technologies at lab bench scale for effectiveness, and conducted a techoeconomic study to evaluate their costs and energy efficiency compared to available baseline technologies. Based on this study, three harvesting technologies were selected for further study at larger scale. We evaluated the selected harvesting technologies: electrocoagulation, membrane filtration, and ultrasonic harvesting, in a field study at minimum scale of 100 L/h. None of the extraction technologies were determined to be ready for scale-up; therefore, an emerging extraction technology (wet solvent extraction) was selected from industry to provide scale-up data and capabilities to produce lipid and lipid-extracted materials for the NAABB program. One specialized extraction/adsorption technology was developed that showed promise for recovering high value co-products from lipid extracts. Overall, the NAABB Harvesting and Extraction Team improved the readiness level of several innovative, energy efficient technologies to integrate with algae production processes and captured valuable lessons learned about scale-up challenges.« less

Review of the harvesting and extraction program within the National Alliance for Advanced Biofuels and Bioproducts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marrone, Babetta L.; Lacey, Ronald E.; Anderson, Daniel B.

Energy-efficient and scalable harvesting and lipid extraction processes must be developed in order for the algal biofuels and bioproducts industry to thrive. The major challenge for harvesting is the handling of large volumes of cultivation water to concentrate low amounts of biomass. For lipid extraction, the major energy and cost drivers are associated with disrupting the algae cell wall and drying the biomass before solvent extraction of the lipids. Here we review the research and development conducted by the Harvesting and Extraction Team during the 3-year National Alliance for Advanced Biofuels and Bioproducts (NAABB) algal consortium project. The harvesting andmore » extraction team investigated five harvesting and three wet extraction technologies at lab bench scale for effectiveness, and conducted a techoeconomic study to evaluate their costs and energy efficiency compared to available baseline technologies. Based on this study, three harvesting technologies were selected for further study at larger scale. We evaluated the selected harvesting technologies: electrocoagulation, membrane filtration, and ultrasonic harvesting, in a field study at minimum scale of 100 L/h. None of the extraction technologies were determined to be ready for scale-up; therefore, an emerging extraction technology (wet solvent extraction) was selected from industry to provide scale-up data and capabilities to produce lipid and lipid-extracted materials for the NAABB program. One specialized extraction/adsorption technology was developed that showed promise for recovering high value co-products from lipid extracts. Overall, the NAABB Harvesting and Extraction Team improved the readiness level of several innovative, energy efficient technologies to integrate with algae production processes and captured valuable lessons learned about scale-up challenges.« less

Membrane Desalination: Where Are We, and What Can We Learn from Fundamentals?

PubMed

Imbrogno, Joseph; Belfort, Georges

2016-06-07

Although thermal desalination technology provides potable water in arid regions (e.g., Israel and the Gulf), its relatively high cost has limited application to less arid regions with large populations (e.g., California). Energy-intensive distillation is currently being replaced with less costly pressure- and electrically driven membrane-based processes. Reverse osmosis (RO) is a preferred membrane technology owing to process and pre- and posttreatment improvements that have significantly reduced energy requirements and cost. Further technical advances will require a deeper understanding of the fundamental science underlying RO. This includes determining the mechanism for water selectivity; elucidating the behavior of molecular water near polar and apolar surfaces, as well as the advantages and limitations of hydrophobic versus hydrophilic pores; learning the rules of selective water transport from nature; and designing synthetic analogs for selective water transport. Molecular dynamics simulations supporting experiments will play an important role in advancing these efforts. Finally, future improvements in RO are limited by inherent technical mass transfer limitations.

Small Engine Component Technology (SECT) studies

NASA Technical Reports Server (NTRS)

Meyer, P. K.; Harbour, L.

1986-01-01

A study was conducted to identify component technology requirements for small, expendable gas turbine engines that would result in substantial improvements in performance and cost by the year 2000. A subsonic, 2600 nautical mile (4815 km) strategic cruise missile mission was selected for study. A baseline (state-of-the-art) engine and missile configuration were defined to evaluate the advanced technology engines. Two advanced technology engines were configured and evaluated using advanced component efficiencies and ceramic composite materials; a 22:1 overall pressure ratio, 3.85 bypass ratio twin-spool turbofan; and an 8:1 overall pressure, 3.66 bypass ratio, single-spool recuperated turbofan with 0.85 recuperator effectiveness. Results of mission analysis indicated a reduction in fuel burn of 38 and 47 percent compared to the baseline engine when using the advanced turbofan and recuperated turbofan, respectively. While use of either advanced engine resulted in approximately a 25 percent reduction in missile size, the unit life cycle (LCC) cost reduction of 56 percent for the advanced turbofan relative to the baseline engine gave it a decisive advantage over the recuperated turbofan with 47 percent LCC reduction. An additional range improvement of 10 percent results when using a 56 percent loaded carbon slurry fuel with either engine. These results can be realized only if significant progress is attained in the fields of solid lubricated bearings, small aerodynamic component performance, composite ceramic materials and integration of slurry fuels. A technology plan outlining prospective programs in these fields is presented.

An Overview of Power Capability Requirements for Exploration Missions

NASA Technical Reports Server (NTRS)

Davis, Jose M.; Cataldo, Robert L.; Soeder, James F.; Manzo, Michelle A.; Hakimzadeh, Roshanak

2005-01-01

Advanced power is one of the key capabilities that will be needed to achieve NASA's missions of exploration and scientific advancement. Significant gaps exist in advanced power capabilities that are on the critical path to enabling human exploration beyond Earth orbit and advanced robotic exploration of the solar system. Focused studies and investment are needed to answer key development issues for all candidate technologies before down-selection. The viability of candidate power technology alternatives will be a major factor in determining what exploration mission architectures are possible. Achieving the capabilities needed to enable the CEV, Moon, and Mars missions is dependent on adequate funding. Focused investment in advanced power technologies for human and robotic exploration missions is imperative now to reduce risk and to make informed decisions on potential exploration mission decisions beginning in 2008. This investment would begin the long lead-time needed to develop capabilities for human exploration missions in the 2015 to 2030 timeframe. This paper identifies some of the key technologies that will be needed to fill these power capability gaps. Recommendations are offered to address capability gaps in advanced power for Crew Exploration Vehicle (CEV) power, surface nuclear power systems, surface mobile power systems, high efficiency power systems, and space transportation power systems. These capabilities fill gaps that are on the critical path to enabling robotic and human exploration missions. The recommendations address the following critical technology areas: Energy Conversion, Energy Storage, and Power Management and Distribution.

Advanced supersonic technology concept study: Hydrogen fueled configuration

NASA Technical Reports Server (NTRS)

Brewer, G. D.

1974-01-01

Conceptual designs of hydrogen fueled supersonic transport configurations for the 1990 time period were developed and compared with equivalent technology Jet A-1 fueled vehicles to determine the economic and performance potential of liquid hydrogen as an alternate fuel. Parametric evaluations of supersonic cruise vehicles with varying design and transport mission characteristics established the basis for selecting a preferred configuration which was then studied in greater detail. An assessment was made of the general viability of the selected concept including an evaluation of costs and environmental considerations, i.e., exhaust emissions and sonic boom characteristics. Technology development requirements and suggested implementation schedules are presented.

Advanced Mirror System Demonstrator (AMSD) Risk Management

NASA Technical Reports Server (NTRS)

Byberg, Alicia; Russell, J. Kevin; Kaukler, Donna; Burdine, Robert V. (Technical Monitor)

2002-01-01

This paper will report risk issues associated with designing, manufacturing, and testing the Advanced Mirror System Demonstrator (AMSD). The Advanced Mirror System Demonstrator (AMSD) will be developed as a lightweight primary mirror system that can be produced at a low cost and with a short manufacturing schedule. This technology will add to the knowledge base for selection for the Next Generation Space Telescope (NGST), Space Based Laser (SBL), Research Laboratory mission (AFRL), and other government agency programs.

Application of a design-build-team approach to low cost and weight composite fuselage structure

NASA Technical Reports Server (NTRS)

Ilcewicz, L. B.; Walker, T. H.; Willden, K. S.; Swanson, G. D.; Truslove, G.; Metschan, S. L.; Pfahl, C. L.

1991-01-01

Relationships between manufacturing costs and design details must be understood to promote the application of advanced composite technologies to transport fuselage structures. A team approach, integrating the disciplines responsible for aircraft structural design and manufacturing, was developed to perform cost and weight trade studies for a twenty-foot diameter aft fuselage section. Baseline composite design and manufacturing concepts were selected for large quadrant panels in crown, side, and keel areas of the fuselage section. The associated technical issues were also identified. Detailed evaluation of crown panels indicated the potential for large weight savings and costs competitive with aluminum technology in the 1995 timeframe. Different processes and material forms were selected for the various elements that comprise the fuselage structure. Additional cost and weight savings potential was estimated for future advancements.

Development of selected advanced aerodynamics and active control concepts for commercial transport aircraft

NASA Technical Reports Server (NTRS)

Taylor, A. B.

1984-01-01

Work done under the Energy Efficient Transport project in the field of advanced aerodynamics and active controls is summarized. The project task selections focused on the following: the investigation of long-duct nacelle shape variation on interference drag; the investigation of the adequacy of a simple control law for the elastic modes of a wing; the development of the aerodynamic technology at cruise and low speed of high-aspect-ratio supercritical wings of high performance; and the development of winglets for a second-generation jet transport. All the tasks involved analysis and substantial wind tunnel testing. The winglet program also included flight evaluation. It is considered that the technology base has been built for the application of high-aspect-ratio supercritical wings and for the use of winglets on second-generation transports.

Advanced BCD technology with vertical DMOS based on a semi-insulation structure

NASA Astrophysics Data System (ADS)

Kui, Ma; Xinghua, Fu; Jiexin, Lin; Fashun, Yang

2016-07-01

A new semi-insulation structure in which one isolated island is connected to the substrate was proposed. Based on this semi-insulation structure, an advanced BCD technology which can integrate a vertical device without extra internal interconnection structure was presented. The manufacturing of the new semi-insulation structure employed multi-epitaxy and selectively multi-doping. Isolated islands are insulated with the substrate by reverse-biased PN junctions. Adjacent isolated islands are insulated by isolation wall or deep dielectric trenches. The proposed semi-insulation structure and devices fixed in it were simulated through two-dimensional numerical computer simulators. Based on the new BCD technology, a smart power integrated circuit was designed and fabricated. The simulated and tested results of Vertical DMOS, MOSFETs, BJTs, resistors and diodes indicated that the proposed semi-insulation structure is reasonable and the advanced BCD technology is validated. Project supported by the National Natural Science Foundation of China (No. 61464002), the Science and Technology Fund of Guizhou Province (No. Qian Ke He J Zi [2014]2066), and the Dr. Fund of Guizhou University (No. Gui Da Ren Ji He Zi (2013)20Hao).

Space Station Systems Technology Study. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1984-01-01

The four study areas addressed are: (1) attitude control, (2) data management, (3) long-life thermal management, and (4) automated housekeeping integration. The design concepts in each area were refined. The cost benefits, schedules, and life cycle costs for the options were evaluated. Technology advancement plans were prepared for each of the selected items, and documentation was prepared.

Advanced supersonic propulsion study, phases 3 and 4. [variable cycle engines

NASA Technical Reports Server (NTRS)

Allan, R. D.; Joy, W.

1977-01-01

An evaluation of various advanced propulsion concepts for supersonic cruise aircraft resulted in the identification of the double-bypass variable cycle engine as the most promising concept. This engine design utilizes special variable geometry components and an annular exhaust nozzle to provide high take-off thrust and low jet noise. The engine also provides good performance at both supersonic cruise and subsonic cruise. Emission characteristics are excellent. The advanced technology double-bypass variable cycle engine offers an improvement in aircraft range performance relative to earlier supersonic jet engine designs and yet at a lower level of engine noise. Research and technology programs required in certain design areas for this engine concept to realize its potential benefits include refined parametric analysis of selected variable cycle engines, screening of additional unconventional concepts, and engine preliminary design studies. Required critical technology programs are summarized.

Proposed Advanced Reactor Adaptation of the Standard Review Plan NUREG-0800 Chapter 4 (Reactor) for Sodium-Cooled Fast Reactors and Modular High-Temperature Gas-Cooled Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belles, Randy; Poore, III, Willis P.; Brown, Nicholas R.

2017-03-01

This report proposes adaptation of the previous regulatory gap analysis in Chapter 4 (Reactor) of NUREG 0800, Standard Review Plan (SRP) for the Review of Safety Analysis Reports for Nuclear Power Plants: LWR [Light Water Reactor] Edition. The proposed adaptation would result in a Chapter 4 review plan applicable to certain advanced reactors. This report addresses two technologies: the sodium-cooled fast reactor (SFR) and the modular high temperature gas-cooled reactor (mHTGR). SRP Chapter 4, which addresses reactor components, was selected for adaptation because of the possible significant differences in advanced non-light water reactor (non-LWR) technologies compared with the current LWR-basedmore » description in Chapter 4. SFR and mHTGR technologies were chosen for this gap analysis because of their diverse designs and the availability of significant historical design detail.« less

The Boom in 3D-Printed Sensor Technology

PubMed Central

Xu, Yuanyuan; Wu, Xiaoyue; Guo, Xiao; Kong, Bin; Zhang, Min; Qian, Xiang; Mi, Shengli; Sun, Wei

2017-01-01

Future sensing applications will include high-performance features, such as toxin detection, real-time monitoring of physiological events, advanced diagnostics, and connected feedback. However, such multi-functional sensors require advancements in sensitivity, specificity, and throughput with the simultaneous delivery of multiple detection in a short time. Recent advances in 3D printing and electronics have brought us closer to sensors with multiplex advantages, and additive manufacturing approaches offer a new scope for sensor fabrication. To this end, we review the recent advances in 3D-printed cutting-edge sensors. These achievements demonstrate the successful application of 3D-printing technology in sensor fabrication, and the selected studies deeply explore the potential for creating sensors with higher performance. Further development of multi-process 3D printing is expected to expand future sensor utility and availability. PMID:28534832

Avionics Architectures for Exploration: Wireless Technologies and Human Spaceflight

NASA Technical Reports Server (NTRS)

Goforth, Montgomery B.; Ratliff, James E.; Barton, Richard J.; Wagner, Raymond S.; Lansdowne, Chatwin

2014-01-01

The authors describe ongoing efforts by the Avionics Architectures for Exploration (AAE) project chartered by NASA's Advanced Exploration Systems (AES) Program to evaluate new avionics architectures and technologies, provide objective comparisons of them, and mature selected technologies for flight and for use by other AES projects. The AAE project team includes members from most NASA centers and from industry. This paper provides an overview of recent AAE efforts, with particular emphasis on the wireless technologies being evaluated under AES to support human spaceflight.

Power Systems for Future Missions: Appendices A-L

NASA Technical Reports Server (NTRS)

Gill, S. P.; Frye, P. E.; Littman, Franklin D.; Meisl, C. J.

1994-01-01

Selection of power system technology for space applications is typically based on mass, readiness of a particular technology to meet specific mission requirements, and life cycle costs (LCC). The LCC is typically used as a discriminator between competing technologies for a single mission application. All other future applications for a given technology are usually ignored. As a result, development cost of a technology becomes a dominant factor in the LCC comparison. Therefore, it is common for technologies such as DIPS and LMR-CBC to be potentially applicable to a wide range of missions and still lose out in the initial LCC comparison due to high development costs. This collection of appendices (A through L) contains the following power systems technology plans: CBC DIPS Technology Roadmap; PEM PFC Technology Roadmap; NAS Battery Technology Roadmap; PV/RFC Power System Technology Roadmap; PV/NAS Battery Technology Roadmap; Thermionic Reactor Power System Technology Roadmap; SP-100 Power System Technology Roadmap; Dynamic SP-100 Power System Technology Roadmap; Near-Term Solar Dynamic Power System Technology Roadmap; Advanced Solar Dynamic Power System Technology Roadmap; Advanced Stirling Cycle Dynamic Isotope Power System Technology Roadmap; and the ESPPRS (Evolutionary Space Power and Propulsion Requirements System) User's Guide.

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

PubMed

Komor, Alexis C; Badran, Ahmed H; Liu, David R

2017-01-12

The CRISPR-Cas9 RNA-guided DNA endonuclease has contributed to an explosion of advances in the life sciences that have grown from the ability to edit genomes within living cells. In this Review, we summarize CRISPR-based technologies that enable mammalian genome editing and their various applications. We describe recent developments that extend the generality, DNA specificity, product selectivity, and fundamental capabilities of natural CRISPR systems, and we highlight some of the remarkable advancements in basic research, biotechnology, and therapeutics science that these developments have facilitated. Copyright © 2017 Elsevier Inc. All rights reserved.

Frameless, image-guided stereotactic radiosurgery.

PubMed

Steffey-Stacy, Emily Cassandra

2006-11-01

To trace the evolution from frame-based to frameless image-guided SRS, to discuss the basic radiobiological principle of fractionation, current clinical trial data, and procedural components of the treatment plan. Nursing and medical literature, neurosurgical textbooks, and select internet sites. The CyberKnife (Accuray, Sunnyvale, CA) is the newest machine added to the technologic armamentarium of patient care. Its capacities are only beginning to be explored and the possibilities are limitless, giving hope to countless persons. Technologic advances have necessitated a diversification of nursing roles. Coordination of patient care services requires nurses to advance their knowledge of frameless, image-guided SRS.

Engineered proteins as specific binding reagents.

PubMed

Binz, H Kaspar; Plückthun, Andreas

2005-08-01

Over the past 30 years, monoclonal antibodies have become the standard binding proteins and currently find applications in research, diagnostics and therapy. Yet, monoclonal antibodies now face strong competition from synthetic antibody libraries in combination with powerful library selection technologies. More recently, an increased understanding of other natural binding proteins together with advances in protein engineering, selection and evolution technologies has also triggered the exploration of numerous other protein architectures for the generation of designed binding molecules. Valuable protein-binding scaffolds have been obtained and represent promising alternatives to antibodies for biotechnological and, potentially, clinical applications.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuruganti, Phani Teja

The smart grid is a combined process of revitalizing the traditional power grid applications and introducing new applications to improve the efficiency of power generation, transmission and distribution. This can be achieved by leveraging advanced communication and networking technologies. Therefore the selection of the appropriate communication technology for different smart grid applications has been debated a lot in the recent past. After comparing different possible technologies, a recent research study has arrived at a conclusion that the 3G cellular technology is the right choice for distribution side smart grid applications like smart metering, advanced distribution automation and demand response managementmore » system. In this paper, we argue that the current 3G/4G cellular technologies are not an appropriate choice for smart grid distribution applications and propose a Hybrid Spread Spectrum (HSS) based Advanced Metering Infrastructure (AMI) as one of the alternatives to 3G/4G technologies. We present a preliminary PHY and MAC layer design of a HSS based AMI network and evaluate their performance using matlab and NS2 simulations. Also, we propose a time hierarchical scheme that can significantly reduce the volume of random access traffic generated during blackouts and the delay in power outage reporting.« less

Proceedings -- US Russian workshop on fuel cell technologies (in English;Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, B.; Sylwester, A.

1996-04-01

On September 26--28, 1995, Sandia National Laboratories sponsored the first Joint US/Russian Workshop on Fuel Cell Technology at the Marriott Hotel in Albuquerque, New Mexico. This workshop brought together the US and Russian fuel cell communities as represented by users, producers, R and D establishments and government agencies. Customer needs and potential markets in both countries were discussed to establish a customer focus for the workshop. Parallel technical sessions defined research needs and opportunities for collaboration to advance fuel cell technology. A desired outcome of the workshop was the formation of a Russian/American Fuel Cell Consortium to advance fuel cellmore » technology for application in emerging markets in both countries. This consortium is envisioned to involve industry and national labs in both countries. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.« less

Medicine.

ERIC Educational Resources Information Center

Ingelfinger, Franz J.

1980-01-01

Selected for discussion are certain advances in basic research and technologic innovation which shape the past, present, and future of medical care. Included are infectious diseases, especially hepatitis, immunology, clinical disorders of the immune system and the histocompatability system. (Author/SA)

Recent advances in 3D printing of biomaterials.

PubMed

Chia, Helena N; Wu, Benjamin M

2015-01-01

3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of-a-kind devices, implants, scaffolds for tissue engineering, diagnostic platforms, and drug delivery systems. Fueled by the recent explosion in public interest and access to affordable printers, there is renewed interest to combine stem cells with custom 3D scaffolds for personalized regenerative medicine. Before 3D Printing can be used routinely for the regeneration of complex tissues (e.g. bone, cartilage, muscles, vessels, nerves in the craniomaxillofacial complex), and complex organs with intricate 3D microarchitecture (e.g. liver, lymphoid organs), several technological limitations must be addressed. In this review, the major materials and technology advances within the last five years for each of the common 3D Printing technologies (Three Dimensional Printing, Fused Deposition Modeling, Selective Laser Sintering, Stereolithography, and 3D Plotting/Direct-Write/Bioprinting) are described. Examples are highlighted to illustrate progress of each technology in tissue engineering, and key limitations are identified to motivate future research and advance this fascinating field of advanced manufacturing.

ADVANCED TOOLS FOR ASSESSING SELECTED ...

EPA Pesticide Factsheets

The purpose of this poster is to present the application and assessment of advanced technologies in a real-world environment - wastewater effluent and source waters - for detecting six drugs (azithromycin, fluoxetine, omeprazole, levothyroxine, methamphetamine, and methylenedioxymethamphetamine). The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and more in-depth coverage of each project. Briefly, each project's objective is stated below.Subtask 1: To integrate state-of-the-art technologies (polar organic chemical integrative samplers, advanced solid-phase extraction methodologies with liquid chromatography/electrospray/mass spectrometry) and apply them to studying the sources and fate of a select list of PPCPs. Application and improvement of analytical methodologies that can detect non-volatile, polar, water-soluble pharmaceuticals in source waters at levels that could be environmentally significant (at concentrations less than parts per billion, ppb). IAG with USGS ends in FY05. APM 20 due in FY05.Subtask 2: Coordination of interagency research and public outreach activities for PPCPs. Participate on NSTC Health and Environment subcommittee working group on PPCPs. Web site maintenance and expansion, invited technica

ADVANCED TOOLS FOR ASSESSING SELECTED ...

EPA Pesticide Factsheets

The purpose of this poster is to present the application and assessment of advanced state-of-the-art technologies in a real-world environment - wastewater effluent and source waters - for detecting six drugs [azithromycin, fluoxetine, omeprazole, levothyroxine, methamphetamine, methylenedioxymethamphetamine (MDMA)]. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and more in-depth coverage of each project. Briefly, each project's objective is stated below.Subtask 1: To integrate state-of-the-art technologies (polar organic chemical integrative samplers, advanced solid-phase extraction methodologies with liquid chromatography/electrospray/mass spectrometry) and apply them to studying the sources and fate of a select list of PPCPs. Application and improvement of analytical methodologies that can detect non-volatile, polar, water-soluble pharmaceuticals in source waters at levels that could be environmentally significant (at concentrations less than parts per billion, ppb). IAG with USGS ends in FY05. APM 20 due in FY05.Subtask 2: Coordination of interagency research and public outreach activities for PPCPs. Participate on NSTC Health and Environment subcommittee working group on PPCPs. Web site maintenance and expansi

Three-dimensional viscous design methodology for advanced technology aircraft supersonic inlet systems

NASA Technical Reports Server (NTRS)

Anderson, B. H.

1983-01-01

A broad program to develop advanced, reliable, and user oriented three-dimensional viscous design techniques for supersonic inlet systems, and encourage their transfer into the general user community is discussed. Features of the program include: (1) develop effective methods of computing three-dimensional flows within a zonal modeling methodology; (2) ensure reasonable agreement between said analysis and selective sets of benchmark validation data; (3) develop user orientation into said analysis; and (4) explore and develop advanced numerical methodology.

Advanced Materials for Exploration Task Research Results

NASA Technical Reports Server (NTRS)

Cook, M. B. (Compiler); Murphy, K. L.; Schneider, T.

2008-01-01

The Advanced Materials for Exploration (AME) Activity in Marshall Space Flight Center s (MSFC s) Exploration Science and Technology Directorate coordinated activities from 2001 to 2006 to support in-space propulsion technologies for future missions. Working together, materials scientists and mission planners identified materials shortfalls that are limiting the performance of long-term missions. The goal of the AME project was to deliver improved materials in targeted areas to meet technology development milestones of NASA s exploration-dedicated activities. Materials research tasks were targeted in five areas: (1) Thermal management materials, (2) propulsion materials, (3) materials characterization, (4) vehicle health monitoring materials, and (5) structural materials. Selected tasks were scheduled for completion such that these new materials could be incorporated into customer development plans.

Advanced Prop-fan Engine Technology (APET) single- and counter-rotation gearbox/pitch change mechanism

NASA Technical Reports Server (NTRS)

Reynolds, C. N.

1985-01-01

The preliminary design of advanced technology (1992) prop-fan engines for single-rotation prop-fans, the conceptual design of the entire propulsion system, and an aircraft evaluation of the resultant designs are discussed. Four engine configurations were examined. A two-spool engine with all axial compressors and a three-spool engine with axial/centrifugal compressors were selected. Integrated propulsion systems were designed in conjunction with airframe manufacturers. The design efforts resulted in 12,000 shaft horsepower engines installed in over the installations with in-line and offset gearboxes. The prop-fan powered aircraft used 21 percent less fuel and cost 10 percent less to operate than a similar aircraft powered by turbofan engines with comparable technology.

Advancement of Tools Supporting Improvement of Work Safety in Selected Industrial Company

NASA Astrophysics Data System (ADS)

Gembalska-Kwiecień, Anna

2018-03-01

In the presented article, the advancement of tools to improve the safety of work in the researched industrial company was taken into consideration. Attention was paid to the skillful analysis of the working environment, which includes the available technologies, work organization and human capital. These factors determine the development of the best prevention activities to minimize the number of accidents.

Human Subjects Protection and Technology in Prevention Science: Selected Opportunities and Challenges.

PubMed

Pisani, Anthony R; Wyman, Peter A; Mohr, David C; Perrino, Tatiana; Gallo, Carlos; Villamar, Juan; Kendziora, Kimberly; Howe, George W; Sloboda, Zili; Brown, C Hendricks

2016-08-01

Internet-connected devices are changing the way people live, work, and relate to one another. For prevention scientists, technological advances create opportunities to promote the welfare of human subjects and society. The challenge is to obtain the benefits while minimizing risks. In this article, we use the guiding principles for ethical human subjects research and proposed changes to the Common Rule regulations, as a basis for discussing selected opportunities and challenges that new technologies present for prevention science. The benefits of conducting research with new populations, and at new levels of integration into participants' daily lives, are presented along with five challenges along with technological and other solutions to strengthen the protections that we provide: (1) achieving adequate informed consent with procedures that are acceptable to participants in a digital age; (2) balancing opportunities for rapid development and broad reach, with gaining adequate understanding of population needs; (3) integrating data collection and intervention into participants' lives while minimizing intrusiveness and fatigue; (4) setting appropriate expectations for responding to safety and suicide concerns; and (5) safeguarding newly available streams of sensitive data. Our goal is to promote collaboration between prevention scientists, institutional review boards, and community members to safely and ethically harness advancing technologies to strengthen impact of prevention science.

Advanced Mirror & Modelling Technology Development

NASA Technical Reports Server (NTRS)

Effinger, Michael; Stahl, H. Philip; Abplanalp, Laura; Maffett, Steven; Egerman, Robert; Eng, Ron; Arnold, William; Mosier, Gary; Blaurock, Carl

2014-01-01

The 2020 Decadal technology survey is starting in 2018. Technology on the shelf at that time will help guide selection to future low risk and low cost missions. The Advanced Mirror Technology Development (AMTD) team has identified development priorities based on science goals and engineering requirements for Ultraviolet Optical near-Infrared (UVOIR) missions in order to contribute to the selection process. One key development identified was lightweight mirror fabrication and testing. A monolithic, stacked, deep core mirror was fused and replicated twice to achieve the desired radius of curvature. It was subsequently successfully polished and tested. A recently awarded second phase to the AMTD project will develop larger mirrors to demonstrate the lateral scaling of the deep core mirror technology. Another key development was rapid modeling for the mirror. One model focused on generating optical and structural model results in minutes instead of months. Many variables could be accounted for regarding the core, face plate and back structure details. A portion of a spacecraft model was also developed. The spacecraft model incorporated direct integration to transform optical path difference to Point Spread Function (PSF) and between PSF to modulation transfer function. The second phase to the project will take the results of the rapid mirror modeler and integrate them into the rapid spacecraft modeler.

[Health technology assessment: a multidisciplinary approach for selecting innovations in the health service].

PubMed

Cavallo, Maria Caterina

2013-01-01

Technological evolution and the increasing requests of a more qualified health care have challenged politicians to evaluate the economical sustainability of proposed innovations. The objective of government health policies is to guarantee real advances in the quality of care to all citizens. Since 1965, independent research centers have analyzed this issue for the US Congress. In 1973, Congress endorsed the establishment of an Office of Technology Assessment (OTA) to discover the best strategies for evaluating such advances. OTA have proposed the following criteria to identify possible beneficial innovations to be introduced into routine health care: effectiveness, safeness, worth, costs, cost-effectiveness ratio and cost patient-benefit ratio. This review analyzes in detail the pathway that each medical innovation follows in order to identify which technological evolutions might prove to be truly beneficial and sustainable for the community.

Small transport aircraft technology propeller study

NASA Technical Reports Server (NTRS)

Black, B. M.; Magliozzi, B.; Rohrbach, C.

1983-01-01

A study to define potential benefits of advanced technology propeller for 1985-1990 STAT commuter airplanes was completed. Two baselines, a Convair, 30 passenger, 0.47 Mach number airplane and a Lockheed, 50 passenger, 0.70 Mach number airplane, were selected from NASA-Ames sponsored airframe contracts. Parametric performance, noise level, weight and cost trends for propellers with varying number of blades, activity factor, camber and diameter incorporating blade sweep, tip proplets, advanced composite materials, advanced airfoils, advanced prevision synchrophasing and counter-rotation are presented. The resulting DOC, fuel burned, empty weight and acquisition cost benefits are presented for resizings of the two baseline airplanes. Six-bladed propeller having advanced composite blades, advanced airfoils, tip proplets and advanced prevision synchrophasers provided the maximum DOC improvements for both airplanes. DOC and fuel burned were reduced by 8.3% and 17.0% respectively for the Convair airplane and by 24.9% and 41.2% respectively for the Lockheed airplane. The larger reductions arose from a baseline definition with very heavy fuselage acoustic treatment. An alternate baseline, with a cabin noise 13dB in excess of the objective, was also studied.

Evolution of the Baseline ISS ECLSS Technologies: The Next Logical Steps

NASA Technical Reports Server (NTRS)

Carrasquillo, Robyn L.; Bagdigian, Bob; Perry, Jay; Lewis, John; Williams, Dave

2004-01-01

The baseline Environmental Control and Life Support Systems which are currently deployed on the International Space Station or planned to be launched in Node 3 are based on technologies selected in the early 1990's. While they are generally meeting or exceeding requirements for supporting the ISS crew, lessons learned from years of on orbit and ground testing, new advances in technology state of the art, and requirements for future manned missions prompt consideration of the next logical step to enhance these systems to increase performance, robustness, reliability, and reduce on-orbit and logistical resource requirements. This paper discusses the current state of the art in ISS ECLSS technologies, and possible areas for enhancement/improvement. Potential utilization of the ISS as a testbed for on-orbit checkout of selected technology improvements is also addressed.

A methodology for spacecraft technology insertion analysis balancing benefit, cost, and risk

NASA Astrophysics Data System (ADS)

Bearden, David Allen

Emerging technologies are changing the way space missions are developed and implemented. Technology development programs are proceeding with the goal of enhancing spacecraft performance and reducing mass and cost. However, it is often the case that technology insertion assessment activities, in the interest of maximizing performance and/or mass reduction, do not consider synergistic system-level effects. Furthermore, even though technical risks are often identified as a large cost and schedule driver, many design processes ignore effects of cost and schedule uncertainty. This research is based on the hypothesis that technology selection is a problem of balancing interrelated (and potentially competing) objectives. Current spacecraft technology selection approaches are summarized, and a Methodology for Evaluating and Ranking Insertion of Technology (MERIT) that expands on these practices to attack otherwise unsolved problems is demonstrated. MERIT combines the modern techniques of technology maturity measures, parametric models, genetic algorithms, and risk assessment (cost and schedule) in a unique manner to resolve very difficult issues including: user-generated uncertainty, relationships between cost/schedule and complexity, and technology "portfolio" management. While the methodology is sufficiently generic that it may in theory be applied to a number of technology insertion problems, this research focuses on application to the specific case of small (<500 kg) satellite design. Small satellite missions are of particular interest because they are often developed under rigid programmatic (cost and schedule) constraints and are motivated to introduce advanced technologies into the design. MERIT is demonstrated for programs procured under varying conditions and constraints such as stringent performance goals, not-to-exceed costs, or hard schedule requirements. MERIT'S contributions to the engineering community are its: unique coupling of the aspects of performance, cost, and schedule; assessment of system level impacts of technology insertion; procedures for estimating uncertainties (risks) associated with advanced technology; and application of heuristics to facilitate informed system-level technology utilization decisions earlier in the conceptual design phase. MERIT extends the state of the art in technology insertion assessment selection practice and, if adopted, may aid designers in determining the configuration of complex systems that meet essential requirements in a timely, cost-effective manner.

Evaluation of undeveloped rocket engine cycle applications to advanced transportation

NASA Technical Reports Server (NTRS)

1990-01-01

Undeveloped pump-fed, liquid propellant rocket engine cycles were assessed and evaluated for application to Next Manned Transportation System (NMTS) vehicles, which would include the evolving Space Transportation System (STS Evolution), the Personnel Launch System (PLS), and the Advanced Manned Launch System (AMLS). Undeveloped engine cycles selected for further analysis had potential for increased reliability, more maintainability, reduced cost, and improved (or possibly level) performance when compared to the existing SSME and proposed STME engines. The split expander (SX) cycle, the full flow staged combustion (FFSC) cycle, and a hybrid version of the FFSC, which has a LOX expander drive for the LOX pump, were selected for definition and analysis. Technology requirements and issues were identified and analyses of vehicle systems weight deltas using the SX and FFSC cycles in AMLS vehicles were performed. A strawman schedule and cost estimate for FFSC subsystem technology developments and integrated engine system demonstration was also provided.

Solar Concentrator Advanced Development Program, Task 1

NASA Technical Reports Server (NTRS)

1986-01-01

Solar dynamic power generation has been selected by NASA to provide power for the space station. Solar dynamic concentrator technology has been demonstrated for terrestrial applications but has not been developed for space applications. The object of the Solar Concentrator Advanced Development program is to develop the technology of solar concentrators which would be used on the space station. The first task of this program was to develop conceptual concentrator designs and perform trade-off studies and to develop a materials data base and perform material selection. Three unique concentrator concepts; Truss Hex, Spline Radial Panel and Domed Fresnel, were developed and evaluated against weighted trade criteria. The Truss Hex concept was recommended for the space station. Materials data base development demonstrated that several material systems are capable of withstanding extended periods of atomic oxygen exposure without undesirable performance degradation. Descriptions of the conceptual designs and materials test data are included.

Toward a laminar-flow-control transport

NASA Technical Reports Server (NTRS)

Sturgeon, R. F.

1978-01-01

Analyses were conducted to define a practical design for an advanced technology laminar flow control (LRC) transport for initial passenger operation in the early 1990's. Mission requirements, appropriate design criteria, and level of technology for the study aircraft were defined. The characteristics of the selected configuration were established, aircraft and LFC subsystems compatible with the mission requirements were defined, and the aircraft was evaluated in terms of fuel efficiency. A wing design integrating the LFC ducting and metering system into advanced composite wing structure was developed, manufacturing procedures for the surface panel design were established, and environmental and structural testing of surface panel components were conducted. Test results revealed a requirement for relatively minor changes in the manufacturing procedures employed, but have shown the general compatibility of both the selected design and the use of composite materials with the requirements of LFC wing surface panels.

Space station commonality analysis

NASA Technical Reports Server (NTRS)

1988-01-01

This study was conducted on the basis of a modification to Contract NAS8-36413, Space Station Commonality Analysis, which was initiated in December, 1987 and completed in July, 1988. The objective was to investigate the commonality aspects of subsystems and mission support hardware while technology experiments are accommodated on board the Space Station in the mid-to-late 1990s. Two types of mission are considered: (1) Advanced solar arrays and their storage; and (2) Satellite servicing. The point of departure for definition of the technology development missions was a set of missions described in the Space Station Mission Requirements Data Base. (MRDB): TDMX 2151 Solar Array/Energy Storage Technology; TDMX 2561 Satellite Servicing and Refurbishment; TDMX 2562 Satellite Maintenance and Repair; TDMX 2563 Materials Resupply (to a free-flyer materials processing platform); TDMX 2564 Coatings Maintenance Technology; and TDMX 2565 Thermal Interface Technology. Issues to be addressed according to the Statement of Work included modularity of programs, data base analysis interactions, user interfaces, and commonality. The study was to consider State-of-the-art advances through the 1990s and to select an appropriate scale for the technology experiments, considering hardware commonality, user interfaces, and mission support requirements. The study was to develop evolutionary plans for the technology advancement missions.

I-5/Gilman advanced technology bridge project

NASA Astrophysics Data System (ADS)

Lanza di Scalea, Francesco; Karbhari, Vistasp M.; Seible, Frieder

2000-04-01

The UCSD led I-5/Gilman Advanced Technology Bridge Project will design and construct a fully functional traffic bridge of advanced composite materials across Interstate 5 in La Jolla, California. Its objective is to demonstrate the use of advanced composite technologies developed by the aerospace industry in commercial applications to increase the life expectancy of new structures and for the rehabilitation of aging infrastructure components. The structure will be a 450 ft long, 60 ft wide cable-stayed bridge supported by a 150 ft A-frame pylon with two vehicular lanes, two bicycle lanes, pedestrian walkways and utility tunnels. The longitudinal girders and pylon will be carbon fiber shells filled with concrete. The transverse deck system will consist of hollow glass/carbon hybrid tubes and a polypropylene fiber reinforced concrete deck with an arch action. Selected cables will be composite. The bridge's structural behavior will be monitored to determine how advanced composite materials perform in civil infrastructure applications. The bridge will be instrumented to obtain performance and structural health data in real time and, where possible, in a remote fashion. The sensors applied to the bridge will include electrical resistance strain gages, fiberoptic Bragg gratings and accelerometers.

National Alliance for Advanced Biofuels and Bio-Products Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olivares, Jose A.; Baxter, Ivan; Brown, Judith

2014-09-30

The main objective of NAABB was to combine science, technology, and engineering expertise from across the nation to break down critical technical barriers to commercialization of algae-based biofuels. The approach was to address technology development across the entire value chain of algal biofuels production, from selection of strains to cultivation, harvesting, extraction, fuel conversion, and agricultural coproduct production. Sustainable practices and financial feasibility assessments ununderscored the approach and drove the technology development.

Technological Advances In The Surgical Treatment Of Movement Disorders

PubMed Central

Gross, Robert E.; McDougal, Margaret E.

2013-01-01

Technological innovations have driven the advancement of the surgical treatment of movement disorders, from the invention of the stereotactic frame to the adaptation of deep brain stimulation (DBS). Along these lines, this review will describe recent advances in getting neuromodulation modalities, including DBS, to the target; and in the delivery of therapy at the target. Recent radiological advances are altering the way that DBS leads are targeted and inserted, by refining the ability to visualize the subcortical targets using high-field strength MRI and other innovations such as diffusion tensor imaging, and the development of novel targeting devices enabling purely anatomical implantations without the need for neurophysiological monitoring. New portable CT scanners also are facilitating lead implantation without monitoring as well as improving radiological verification of DBS lead location. Advances in neurophysiological mapping include efforts to develop automatic target verification algorithms, and probabilistic maps to guide target selection. The delivery of therapy at the target is being improved by the development of the next generation of internal pulse generators (IPGs). These include constant current devices that mitigate the variability introduced by impedance changes of the stimulated tissue, and in the near future, devices that deliver novel stimulation patterns with improved efficiency. Closed-loop adaptive IPGs are being tested, which may tailor stimulation to ongoing changes in the nervous system reflected in Œbiomarkers1 continuously recorded by the devices. Finer grained DBS leads, in conjunction with new IPGs and advanced programming tools, may offer improved outcomes via Œcurrent steering1 algorithms. Finally, even thermocoagulation - essentially replaced by DBS - is being advanced by new Œminimally-invasive1 approaches that may improve this therapy for selected patients in whom it may be preferred. Functional neurosurgery has a history of being driven by technological innovation, a tradition that continues into its future. PMID:23812894

Process for selecting NEAMS applications for access to Idaho National Laboratory high performance computing resources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michael Pernice

2010-09-01

INL has agreed to provide participants in the Nuclear Energy Advanced Mod- eling and Simulation (NEAMS) program with access to its high performance computing (HPC) resources under sponsorship of the Enabling Computational Technologies (ECT) program element. This report documents the process used to select applications and the software stack in place at INL.

Advanced Technology Composite Fuselage - Materials and Processes

NASA Technical Reports Server (NTRS)

Scholz, D. B.; Dost, E. F.; Flynn, B. W.; Ilcewicz, L. B.; Nelson, K. M.; Sawicki, A. J.; Walker, T. H.; Lakes, R. S.

1997-01-01

The goal of Boeing's Advanced Technology Composite Aircraft Structures (ATCAS) program was to develop the technology required for cost and weight efficient use of composite materials in transport fuselage structure. This contractor report describes results of material and process selection, development, and characterization activities. Carbon fiber reinforced epoxy was chosen for fuselage skins and stiffening elements and for passenger and cargo floor structures. The automated fiber placement (AFP) process was selected for fabrication of monolithic and sandwich skin panels. Circumferential frames and window frames were braided and resin transfer molded (RTM'd). Pultrusion was selected for fabrication of floor beams and constant section stiffening elements. Drape forming was chosen for stringers and other stiffening elements. Significant development efforts were expended on the AFP, braiding, and RTM processes. Sandwich core materials and core edge close-out design concepts were evaluated. Autoclave cure processes were developed for stiffened skin and sandwich structures. The stiffness, strength, notch sensitivity, and bearing/bypass properties of fiber-placed skin materials and braided/RTM'd circumferential frame materials were characterized. The strength and durability of cocured and cobonded joints were evaluated. Impact damage resistance of stiffened skin and sandwich structures typical of fuselage panels was investigated. Fluid penetration and migration mechanisms for sandwich panels were studied.

The use of advanced medical technologies at home: a systematic review of the literature.

PubMed

Ten Haken, Ingrid; Ben Allouch, Somaya; van Harten, Wim H

2018-02-26

The number of medical technologies used in home settings has increased substantially over the last 10-15 years. In order to manage their use and to guarantee quality and safety, data on usage trends and practical experiences are important. This paper presents a literature review on types, trends and experiences with the use of advanced medical technologies at home. The study focused on advanced medical technologies that are part of the technical nursing process and 'hands on' processes by nurses, excluding information technology such as domotica. The systematic review of literature was performed by searching the databases MEDLINE, Scopus and Cinahl. We included papers from 2000 to 2015 and selected articles containing empirical material. The review identified 87 relevant articles, 62% was published in the period 2011-2015. Of the included studies, 45% considered devices for respiratory support, 39% devices for dialysis and 29% devices for oxygen therapy. Most research has been conducted on the topic 'user experiences' (36%), mainly regarding patients or informal caregivers. Results show that nurses have a key role in supporting patients and family caregivers in the process of homecare with advanced medical technologies and in providing information for, and as a member of multi-disciplinary teams. However, relatively low numbers of articles were found studying nurses perspective. Research on medical technologies used at home has increased considerably until 2015. Much is already known on topics, such as user experiences; safety, risks, incidents and complications; and design and technological development. We also identified a lack of research exploring the views of nurses with regard to medical technologies for homecare, such as user experiences of nurses with different technologies, training, instruction and education of nurses and human factors by nurses in risk management and patient safety.

Avionics systems integration technology

NASA Technical Reports Server (NTRS)

Stech, George; Williams, James R.

1988-01-01

A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

Report on the Development of the Advanced Encryption Standard (AES).

PubMed

Nechvatal, J; Barker, E; Bassham, L; Burr, W; Dworkin, M; Foti, J; Roback, E

2001-01-01

In 1997, the National Institute of Standards and Technology (NIST) initiated a process to select a symmetric-key encryption algorithm to be used to protect sensitive (unclassified) Federal information in furtherance of NIST's statutory responsibilities. In 1998, NIST announced the acceptance of 15 candidate algorithms and requested the assistance of the cryptographic research community in analyzing the candidates. This analysis included an initial examination of the security and efficiency characteristics for each algorithm. NIST reviewed the results of this preliminary research and selected MARS, RC™, Rijndael, Serpent and Twofish as finalists. Having reviewed further public analysis of the finalists, NIST has decided to propose Rijndael as the Advanced Encryption Standard (AES). The research results and rationale for this selection are documented in this report.

Technology to Reduce Hypoglycemia

PubMed Central

Yeoh, Ester; Choudhary, Pratik

2015-01-01

Hypoglycemia is a major barrier toward achieving glycemic targets and is associated with significant morbidity (both psychological and physical) and mortality. This article reviews technological strategies, from simple to more advanced technologies, which may help prevent or mitigate exposure to hypoglycemia. More efficient insulin delivery systems, bolus advisor calculators, data downloads providing information on glucose trends, continuous glucose monitoring with alarms warning of hypoglycemia, predictive algorithms, and finally closed loop insulin delivery systems are reviewed. The building blocks to correct use and interpretation of this range of available technology require patient education and appropriate patient selection. PMID:25883167

Sequencing technologies - the next generation.

PubMed

Metzker, Michael L

2010-01-01

Demand has never been greater for revolutionary technologies that deliver fast, inexpensive and accurate genome information. This challenge has catalysed the development of next-generation sequencing (NGS) technologies. The inexpensive production of large volumes of sequence data is the primary advantage over conventional methods. Here, I present a technical review of template preparation, sequencing and imaging, genome alignment and assembly approaches, and recent advances in current and near-term commercially available NGS instruments. I also outline the broad range of applications for NGS technologies, in addition to providing guidelines for platform selection to address biological questions of interest.

NASA Aerospace Flight Battery Systems Program Update

NASA Technical Reports Server (NTRS)

Manzo, Michelle; ODonnell, Patricia

1997-01-01

The objectives of NASA's Aerospace Flight Battery Systems Program is to: develop, maintain and provide tools for the validation and assessment of aerospace battery technologies; accelerate the readiness of technology advances and provide infusion paths for emerging technologies; provide NASA projects with the required database and validation guidelines for technology selection of hardware and processes relating to aerospace batteries; disseminate validation and assessment tools, quality assurance, reliability, and availability information to the NASA and aerospace battery communities; and ensure that safe, reliable batteries are available for NASA's future missions.

Digital SPC switching technology: Foreign technology assessment

NASA Astrophysics Data System (ADS)

Fischman, Kurt; Jorstad, Norman D.

1990-12-01

This paper provides a foreign technology assessment of digital switching technology. Leading suppliers of digital switching technology are identified; although the United States holds a large part of the market, major companies in France, Sweden, Japan, the U.K., and Germany are also important. These countries, along with Belgium and Canada, are the most innovative and technically advanced. A listing is provided of transfers of digital switching technology to non-COCOM countries through licensing and joint ventures which reflects the widespread dissemination of this technology. Detailed technical specifications are provided for selected digital switching systems worldwide. The report concludes that considering the degree to which the technology is in place, that control of digital switching technology may not be feasible.

Closing the design loop on HiMAT (highly maneuverable aircraft technology)

NASA Technical Reports Server (NTRS)

Putnam, T. W.; Robinson, M. R.

1984-01-01

The design methodology used in the HiMAT program and the wind tunnel development activities are discussed. Selected results from the flight test program are presented and the strengths and weaknesses of testing advanced technology vehicles using the RPV concept is examined. The role of simulation on the development of digital flight control systems and in RPV's in particular is emphasized.

ACEE Composite Structures Technology: Review of selected NASA research on composite materials and structures

NASA Technical Reports Server (NTRS)

1984-01-01

The NASA Aircraft Energy Efficiency (ACEE) Composite Primary Aircraft Structures Program was designed to develop technology for advanced composites in commercial aircraft. Research on composite materials, aircraft structures, and aircraft design is presented herein. The following parameters of composite materials were addressed: residual strength, damage tolerance, toughness, tensile strength, impact resistance, buckling, and noise transmission within composite materials structures.

From Dewey to Gates: A Model to Integrate Psychoeducational Principles in the Selection and Use of Instructional Technology

ERIC Educational Resources Information Center

Salinas, M. F.

2008-01-01

The purpose of this article is to propose a model to integrate educational mastery principles that emphasize cooperative and learner-centered instruction in higher education with the new advances of instructional technology, and to present a pilot case study to exemplify the model. It is clear that in spite of tremendous efforts by colleges and…

Storage systems for solar thermal power

NASA Technical Reports Server (NTRS)

Calogeras, J. E.; Gordon, L. H.

1978-01-01

The development status is reviewed of some thermal energy storage technologies specifically oriented towards providing diurnal heat storage for solar central power systems and solar total energy systems. These technologies include sensible heat storage in caverns and latent heat storage using both active and passive heat exchange processes. In addition, selected thermal storage concepts which appear promising to a variety of advanced solar thermal system applications are discussed.

CapiBRIC- Capillary-Based Brine Residual In-Containment for Secondary Water Recovery

NASA Technical Reports Server (NTRS)

Sargusingh, Miriam; Pensinger, S.; Callahan, M.

2015-01-01

One of the goals of the AES Life Support Systems Project is to achieve 98% water loop closure for long-duration human exploration missions. Brine water recovery is the primary technology gap that must be bridged to realize this goal. In response to an Agency call for technologies to compete in an October down-select, Capi-BRIC was chosen through a JSC down-select as the strongest candidate to go forward. This resulted in a period of intense development to increase its TRL in preparation for the Agency down-select. This was achieved through rapid prototype design, fabrication, and test at JSC and in a zero-g drop tower at Portland State University. INNOVATION CapiBRIC takes a novel approach of optimizing the containment geometry to support capillary flow and static phase separation to enable evaporation in a microgravity environment. OUTCOME TRL was advanced from 3 to 4, and was selected for continued funding through the AES program. CapiBRIC is poised for development into an ISS technology demonstration, proving its viability as an enabling technology for exploration.

Technology to Reduce Hypoglycemia.

PubMed

Yeoh, Ester; Choudhary, Pratik

2015-07-01

Hypoglycemia is a major barrier toward achieving glycemic targets and is associated with significant morbidity (both psychological and physical) and mortality. This article reviews technological strategies, from simple to more advanced technologies, which may help prevent or mitigate exposure to hypoglycemia. More efficient insulin delivery systems, bolus advisor calculators, data downloads providing information on glucose trends, continuous glucose monitoring with alarms warning of hypoglycemia, predictive algorithms, and finally closed loop insulin delivery systems are reviewed. The building blocks to correct use and interpretation of this range of available technology require patient education and appropriate patient selection. © 2015 Diabetes Technology Society.

Design feasibility of an advanced technology supersonic cruise aircraft

NASA Technical Reports Server (NTRS)

Rowe, W. T.

1976-01-01

Research and development programs provide confidence that technology is in-hand to design an economically attractive, environmentally sound supersonic cruise aircraft for commercial operations. The principal results of studies and tests are described including those which define the selection of significant design features. These typically include the results of: (1) wind-tunnel tests, both subsonic and supersonic, (2) propulsion performance and acoustic tests on noise suppressors, including forward-flight effects, (3) studies of engine/airframe integration, which lead to the selection of engine cycles/sizes to meet future market, economic, and social requirements; and (4) structural testing.

Extended papers selected from ESSDERC 2015

NASA Astrophysics Data System (ADS)

Grasser, Tibor; Schmitz, Jurriaan; Lemme, Max C.

2016-11-01

This special issue of Solid State Electronics includes 28 papers which have been carefully selected from the best presentations given at the 45th European Solid-State Device Research Conference (ESSDERC 2015) held from September 14-18, 2015 in Graz, Austria. These papers cover a wide range of topics related to the research on solid-state devices. These topics are used also to organize the conference submissions and presentations into 7 tracks: CMOS Processes, Devices and Integration; Opto-, Power- and Microwave Devices; Modeling & Simulation; Characterization, Reliability & Yield; Advanced & Emerging Memories; MEMS, Sensors & Display Technologies; Emerging Non-CMOS Devices & Technologies.

Accelerating the commercialization of university technologies for military healthcare applications: the role of the proof of concept process

NASA Astrophysics Data System (ADS)

Ochoa, Rosibel; DeLong, Hal; Kenyon, Jessica; Wilson, Eli

2011-06-01

The von Liebig Center for Entrepreneurism and Technology Advancement at UC San Diego (vonliebig.ucsd.edu) is focused on accelerating technology transfer and commercialization through programs and education on entrepreneurism. Technology Acceleration Projects (TAPs) that offer pre-venture grants and extensive mentoring on technology commercialization are a key component of its model which has been developed over the past ten years with the support of a grant from the von Liebig Foundation. In 2010, the von Liebig Entrepreneurism Center partnered with the U.S. Army Telemedicine and Advanced Technology Research Center (TATRC), to develop a regional model of Technology Acceleration Program initially focused on military research to be deployed across the nation to increase awareness of military medical needs and to accelerate the commercialization of novel technologies to treat the patient. Participants to these challenges are multi-disciplinary teams of graduate students and faculty in engineering, medicine and business representing universities and research institutes in a region, selected via a competitive process, who receive commercialization assistance and funding grants to support translation of their research discoveries into products or services. To validate this model, a pilot program focused on commercialization of wireless healthcare technologies targeting campuses in Southern California has been conducted with the additional support of Qualcomm, Inc. Three projects representing three different universities in Southern California were selected out of forty five applications from ten different universities and research institutes. Over the next twelve months, these teams will conduct proof of concept studies, technology development and preliminary market research to determine the commercial feasibility of their technologies. This first regional program will help build the needed tools and processes to adapt and replicate this model across other regions in the Country.

New Frontiers AO: Advanced Materials Bi-propellant Rocket (AMBR) Engine Information Summary

NASA Technical Reports Server (NTRS)

Liou, Larry C.

2008-01-01

The Advanced Material Bi-propellant Rocket (AMBR) engine is a high performance (I(sub sp)), higher thrust, radiation cooled, storable bi-propellant space engine of the same physical envelope as the High Performance Apogee Thruster (HiPAT(TradeMark)). To provide further information about the AMBR engine, this document provides details on performance, development, mission implementation, key spacecraft integration considerations, project participants and approach, contact information, system specifications, and a list of references. The In-Space Propulsion Technology (ISPT) project team at NASA Glenn Research Center (GRC) leads the technology development of the AMBR engine. Their NASA partners were Marshall Space Flight Center (MSFC) and Jet Propulsion Laboratory (JPL). Aerojet leads the industrial partners selected competitively for the technology development via the NASA Research Announcement (NRA) process.

AICD -- Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program. 1993 Annual summary report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petersen, G.; Bair, K.; Ross, J.

1994-03-01

The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, a listingmore » of program output, including a bibliography of published work, patents, and awards arising from work supported by BCTR.« less

Smart Buildings: An Introduction to the Library of the Future.

PubMed

Hoy, Matthew B

2016-01-01

Advances in building technologies are combining energy efficiency, networked sensors, and data recording in exciting ways. Modern facilities can adjust lighting, heating, and cooling outputs to maximize efficiency, provide better physical security, improve wayfinding for occupants, and provide detailed reports of building use. This column will briefly explore the idea of "smart buildings," describe some of the technologies that are being developed for these buildings, and explore their implications for libraries. A brief listing of selected smart building technologies is also provided.

Advancing Plug-In Hybrid Technology and Flex Fuel Application on a Chrysler Minivan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bazzi, Abdullah; Barnhart, Steven

2014-12-31

FCA US LLC viewed this DOE funding as a historic opportunity to begin the process of achieving required economies of scale on technologies for electric vehicles. The funding supported FCA US LLC’s light-duty electric drive vehicle and charging infrastructure-testing activities and enabled FCA US LLC to utilize the funding on advancing Plug-in Hybrid Electric Vehicle (PHEV) technologies to future programs. FCA US LLC intended to develop the next generations of electric drive and energy batteries through a properly paced convergence of standards, technology, components, and common modules, as well as first-responder training and battery recycling. To support the development ofmore » a strong, commercially viable supplier base, FCA US LLC also used this opportunity to evaluate various designated component and sub-system suppliers. The original project proposal was submitted in December 2009 and selected in January 2010. The project ended in December 2014.« less

Economics of ion propulsion for large space systems

NASA Technical Reports Server (NTRS)

Masek, T. D.; Ward, J. W.; Rawlin, V. K.

1978-01-01

This study of advanced electrostatic ion thrusters for space propulsion was initiated to determine the suitability of the baseline 30-cm thruster for future missions and to identify other thruster concepts that would better satisfy mission requirements. The general scope of the study was to review mission requirements, select thruster designs to meet these requirements, assess the associated thruster technology requirements, and recommend short- and long-term technology directions that would support future thruster needs. Preliminary design concepts for several advanced thrusters were developed to assess the potential practical difficulties of a new design. This study produced useful general methodologies for assessing both planetary and earth orbit missions. For planetary missions, the assessment is in terms of payload performance as a function of propulsion system technology level. For earth orbit missions, the assessment is made on the basis of cost (cost sensitivity to propulsion system technology level).

Promoting the Appropriate Use of Advanced Radiation Technologies in Oncology: Summary of a National Cancer Policy Forum Workshop.

PubMed

Smith, Grace L; Ganz, Patricia A; Bekelman, Justin E; Chmura, Steven J; Dignam, James J; Efstathiou, Jason A; Jagsi, Reshma; Johnstone, Peter A; Steinberg, Michael L; Williams, Stephen B; Yu, James B; Zietman, Anthony L; Weichselbaum, Ralph R; Tina Shih, Ya-Chen

2017-03-01

Leaders in the oncology community are sounding a clarion call to promote "value" in cancer care decisions. Value in cancer care considers the clinical effectiveness, along with the costs, when selecting a treatment. To discuss possible solutions to the current obstacles to achieving value in the use of advanced technologies in oncology, the National Cancer Policy Forum of the National Academies of Sciences, Engineering, and Medicine held a workshop, "Appropriate Use of Advanced Technologies for Radiation Therapy and Surgery in Oncology" in July 2015. The present report summarizes the discussions related to radiation oncology. The workshop convened stakeholders, including oncologists, researchers, payers, policymakers, and patients. Speakers presented on key themes, including the rationale for a value discussion on advanced technology use in radiation oncology, the generation of scientific evidence for value of advanced radiation technologies, the effect of both scientific evidence and "marketplace" (or economic) factors on the adoption of technologies, and newer approaches to improving value in the practice of radiation oncology. The presentations were followed by a panel discussion with dialogue among the stakeholders. Challenges to generating evidence for the value of advanced technologies include obtaining contemporary, prospective, randomized, and representative comparative effectiveness data. Proposed solutions include the use of prospective registry data; integrating radiation oncology treatment, outcomes, and quality benchmark data; and encouraging insurance coverage with evidence development. Challenges to improving value in practice include the slow adoption of higher value and the de-adoption of lower value treatments. The proposed solutions focused on engaging stakeholders in iterative, collaborative, and evidence-based efforts to define value and promote change in radiation oncology practice. Recent examples of ongoing or successful responses to the discussed challenges were provided. Discussions of "value" have increased as a priority in the radiation oncology community. Practitioners in the radiation oncology community can play a critical role in promoting a value-oriented framework to approach radiation oncology treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

Remaining Technical Challenges and Future Plans for Oil-Free Turbomachinery

NASA Technical Reports Server (NTRS)

DellaCorte, Christopher; Bruckner, Robert J.

2010-01-01

The application of Oil-Free technologies (foil gas bearings, solid lubricants and advanced analysis and predictive modeling tools) to advanced turbomachinery has been underway for several decades. During that time, full commercialization has occurred in aircraft air cycle machines, turbocompressors and cryocoolers and ever-larger microturbines. Emerging products in the automotive sector (turbochargers and superchargers) indicate that high volume serial production of foil bearings is imminent. Demonstration of foil bearings in APU s and select locations in propulsion gas turbines illustrates that such technology also has a place in these future systems. Foil bearing designs, predictive tools and advanced solid lubricants have been reported that can satisfy anticipated requirements but a major question remains regarding the scalability of foil bearings to ever larger sizes to support heavier rotors. In this paper, the technological history, primary physics, engineering practicalities and existing experimental and experiential database for scaling foil bearings are reviewed and the major remaining technical challenges are identified.

Use, perceptions, and benefits of automotive technologies among aging drivers.

PubMed

Eby, David W; Molnar, Lisa J; Zhang, Liang; St Louis, Renée M; Zanier, Nicole; Kostyniuk, Lidia P; Stanciu, Sergiu

2016-12-01

Advanced in-vehicle technologies have been proposed as a potential way to keep older adults driving for as long as they can safely do so, by taking into account the common declines in functional abilities experienced by older adults. The purpose of this report was to synthesize the knowledge about older drivers and advanced in-vehicle technologies, focusing on three areas: use (how older drivers use these technologies), perception (what they think about the technologies), and outcomes (the safety and/or comfort benefits of the technologies). Twelve technologies were selected for review and grouped into three categories: crash avoidance systems (lane departure warning, curve speed warning, forward collision warning, blind spot warning, parking assistance); in-vehicle information systems (navigation assistance, intelligent speed adaptation); and other systems (adaptive cruise control, automatic crash notification, night vision enhancement, adaptive headlight, voice activated control). A comprehensive and systematic search was conducted for each technology to collect related publications. 271 articles were included into the final review. Research findings for each of the 12 technologies are synthesized in relation to how older adults use and think about the technologies as well as potential benefits. These results are presented separately for each technology. Can advanced in-vehicle technologies help extend the period over which an older adult can drive safely? This report answers this question with an optimistic "yes." Some of the technologies reviewed in this report have been shown to help older drivers avoid crashes, improve the ease and comfort of driving, and travel to places and at times that they might normally avoid.

Amorphous or Crystalline? A Comparison of Particle Engineering Methods and Selection.

PubMed

Thakkar, Sachin G; Fathe, Kristin; Smyth, Hugh D C

2015-01-01

This review is intended to provide a critical account of the current goals and technologies of particle engineering regarding the production of crystalline and amorphous particles. The technologies discussed here cover traditional crystallization technologies, supercritical fluid technologies, spray drying, controlled solvent crystallization, and sonocrystallization. Also recent advancements in particle engineering including spray freezing into liquid, thin-film freeze-drying, PRINT technology are presented. The paper also examines the merits and limitations of these technologies with respect to their methods of characterization. Additionally a section discussing the utility of creating amorphous and crystalline formulation approaches in regards to bioavailability and utility in formulation is presented.

Advancements of molecularly imprinted polymers in the food safety field.

PubMed

Wang, Peilong; Sun, Xiaohua; Su, Xiaoou; Wang, Tie

2016-06-07

Molecularly imprinted technology (MIT) has been widely employed to produce stable, robust and cheap molecularly imprinted polymer (MIP) materials that possess selective binding sites for recognition of target analytes in food, such as pesticides, veterinary drugs, mycotoxins, illegal drugs and so on. Because of high selectivity and specificity, MIPs have drawn great attention in the food safety field. In this review, the recent developments of MIPs in various applications for food safety, including sample preparation, chromatographic separation, sensing, immunoassay etc., have been summarized. We particularly discuss the advancements and limitations in these applications, as well as attempts carried out for their improvement.

Advances in Patellofemoral Arthroplasty.

PubMed

Strickland, Sabrina M; Bird, Mackenzie L; Christ, Alexander B

2018-06-01

To describe current indications, implants, economic benefits, comparison to TKA, and functional and patient-reported outcomes of patellofemoral arthroplasty. Modern onlay implants and improved patient selection have allowed for recent improvements in short- and long-term outcomes after patellofemoral joint replacement surgery. Patellofemoral arthroplasty has become an increasingly utilized technique for the successful treatment of isolated patellofemoral arthritis. Advances in patient selection, implant design, and surgical technique have resulted in improved performance and longevity of these implants. Although short- and mid-term data for modern patellofemoral arthroplasties appear promising, further long-term clinical studies are needed to evaluate how new designs and technologies will affect patient outcomes and long-term implant performance.

Ventricular Assist Device and Destination Therapy Candidates from Preoperative Selection Through End of Hospitalization.

PubMed

Doty, Diane

2015-12-01

Mechanical circulatory support (MCS) devices offer advanced heart failure patients a potential long-term solution. MCS devices implantation is increasing related to the increased volume of heart failure patients, the shortfall of suitable donors, and the advanced technology and smaller size of the devices. To ensure a successful outcome, some key elements must be taken into consideration and managed: patient selection, preoperative preparation, intraoperative care, postoperative care, and posthospital education. The ultimate success of an MCS implantation relies on a multidisciplinary approach and excellent patient/caregiver education in each phase of hospitalization. Copyright © 2015 Elsevier Inc. All rights reserved.

Estimating resource selection with count data

Treesearch

Ryan M. Nielson; Hall Sawyer

2013-01-01

Resource selection functions (RSFs) are typically estimated by comparing covariates at a discrete set of “used” locations to those from an “available” set of locations. This RSF approach treats the response as binary and does not account for intensity of use among habitat units where locations were recorded. Advances in global positioning system (GPS) technology allow...

[Recent advances of anastomosis techniques of esophagojejunostomy after laparoscopic totally gastrectomy in gastric tumor].

PubMed

Li, Xi; Ke, Chongwei

2015-05-01

The esophageal jejunum anastomosis of the digestive tract reconstruction techniques in laparoscopic total gastrectomy includes two categories: circular stapler anastomosis techniques and linear stapler anastomosis techniques. Circular stapler anastomosis techniques include manual anastomosis method, purse string instrument method, Hiki improved special anvil anastomosis technique, the transorally inserted anvil(OrVil(TM)) and reverse puncture device technique. Linear stapler anastomosis techniques include side to side anastomosis technique and Overlap side to side anastomosis technique. Esophageal jejunum anastomosis technique has a wide selection of different technologies with different strengths and the corresponding limitations. This article will introduce research progress of laparoscopic total gastrectomy esophagus jejunum anastomosis from both sides of the development of anastomosis technology and the selection of anastomosis technology.

Benefits of Integration of Aerojet Rocketdyne and RTI Advanced Gasification Technologies for Hydrogen-Rich Syngas Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, Vijay; Denton, David; SHarma, Pradeep

The key objective for this project was to evaluate the potential to achieve substantial reductions in the production cost of H 2-rich syngas via coal gasification with near-zero emissions due to the cumulative and synergistic benefits realized when multiple advanced technologies are integrated into the overall conversion process. In this project, Aerojet Rocketdyne’s (AR’s) advanced gasification technology (currently being offered as R-GAS™) and RTI International’s (RTI’s) advanced warm syngas cleanup technologies were evaluated via a number of comparative techno-economic case studies. AR’s advanced gasification technology consists of a dry solids pump and a compact gasifier system. Based on the uniquemore » design of this gasifier, it has been shown to reduce the capital cost of the gasification block by between 40 and 50%. At the start of this project, actual experimental work had been demonstrated through pilot plant systems for both the gasifier and dry solids pump. RTI’s advanced warm syngas cleanup technologies consist primarily of RTI’s Warm Gas Desulfurization Process (WDP) technology, which effectively allows decoupling of the sulfur and CO 2 removal allowing for more flexibility in the selection of the CO 2 removal technology, plus associated advanced technologies for direct sulfur recovery and water gas shift (WGS). WDP has been demonstrated at pre-commercial scale using an activated amine carbon dioxide recovery process which would not have been possible if a majority of the sulfur had not been removed from the syngas by WDP. This pre-commercial demonstration of RTI’s advanced warm syngas cleanup system was conducted in parallel to the activities on this project. The technical data and cost information from this pre-commercial demonstration were extensively used in this project during the techno-economic analysis. With this project, both of RTI’s advanced WGS technologies were investigated. Because RT’s advanced fixed-bed WGS (AFWGS) process was successfully implemented in the WDP pre-commercial demonstration test mentioned above, this technology was used as part of RTI’s advanced warm syngas technology package for the techno-economic analyses for this project. RTI’s advanced transport-reactor-based WGS (ATWGS) process was still conceptual at the start of this project, but one of the tasks for this project was to evaluate the technical feasibility of this technology. In each of the three application-based comparison studies conducted as part of this project, the reference case was based on an existing Department of Energy National Energy Technology Laboratory (DOE/NETL) system study. Each of these references cases used existing commercial technology and the system resulted in > 90% carbon capture. In the comparison studies for the use of the hydrogen-rich syngas generated in either an Integrated Gasification Combined Cycle (IGCC) or a Coal-to-Methanol (CTM) plant, the comparison cases consisted of the reference case, a case with the integration of each individual advanced technology (either AR or RTI), and finally a case with the integration of all the advanced technologies (AR and RTI combined). In the Coal-to-Liquids (CTL) comparison study, the comparison study consisted of only three cases, which included a reference case, a case with just RTI’s advanced syngas cleaning technology, and a case with AR’s and RTI’s advanced technologies. The results from these comparison studies showed that the integration of the advanced technologies did result in substantial benefits, and by far the greatest benefits were achieved for cases integrating all the advanced technologies. For the IGCC study, the fully integrated case resulted in a 1.4% net efficiency improvement, an 18% reduction in capital cost per kW of capacity, a 12% reduction in the operating cost per kWh, and a 75–79% reduction in sulfur emissions. For the CTM case, the fully integrated plant resulted in a 22% reduction in capital cost, a 13% reduction in operating costs, a > 99% net reduction in sulfur emissions, and a reduction of 13–15% in CO 2 emissions. Because the capital cost represents over 60% of the methanol Required Selling Price (RSP), the significant reduction in the capital cost for the advanced technology case resulted in an 18% reduction in methanol RSP. For the CTL case, the fully integrated plant resulted in a 16% reduction in capital cost, which represented a 13% reduction in diesel RSP. Finally, the technical feasibility analysis of RTI’s ATWGS process demonstrated that a fluid-bed catalyst with sufficient attrition resistance and WGS activity could be made and that the process achieved about a 24% reduction in capital cost compared to a conventional fixed-bed commercial process.« less

Advanced ECG in 2016: is there more than just a tracing?

PubMed

Reichlin, Tobias; Abächerli, Roger; Twerenbold, Raphael; Kühne, Michael; Schaer, Beat; Müller, Christian; Sticherling, Christian; Osswald, Stefan

2016-01-01

The 12-lead electrocardiogram (ECG) is the most frequently used technology in clinical cardiology. It is critical for evidence-based management of patients with most cardiovascular conditions, including patients with acute myocardial infarction, suspected chronic cardiac ischaemia, cardiac arrhythmias, heart failure and implantable cardiac devices. In contrast to many other techniques in cardiology, the ECG is simple, small, mobile, universally available and cheap, and therefore particularly attractive. Standard ECG interpretation mainly relies on direct visual assessment. The progress in biomedical computing and signal processing, and the available computational power offer fascinating new options for ECG analysis relevant to all fields of cardiology. Several digital ECG markers and advanced ECG technologies have shown promise in preliminary studies. This article reviews promising novel surface ECG technologies in three different fields. (1) For the detection of myocardial ischaemia and infarction, QRS morphology feature analysis, the analysis of high frequency QRS components (HF-QRS) and methods using vectorcardiography as well as ECG imaging are discussed. (2) For the identification and management of patients with cardiac arrhythmias, methods of advanced P-wave analysis are discussed and the concept of ECG imaging for noninvasive localisation of cardiac arrhythmias is presented. (3) For risk stratification of sudden cardiac death and the selection of patients for medical device therapy, several novel markers including an automated QRS-score for scar quantification, the QRS-T angle or the T-wave peak-to-end-interval are discussed. Despite the existing preliminary data, none of the advanced ECG markers and technologies has yet accomplished the transition into clinical practice. Further refinement of these technologies and broader validation in large unselected patient cohorts are the critical next step needed to facilitate translation of advanced ECG technologies into clinical cardiology.

Recent Progress in Engine Noise Reduction Technologies

NASA Technical Reports Server (NTRS)

Huff, Dennis; Gliebe, Philip

2003-01-01

Highlights from NASA-funded research over the past ten years for aircraft engine noise reduction are presented showing overall technical plans, accomplishments, and selected applications to turbofan engines. The work was sponsored by NASA's Advanced Subsonic Technology (AST) Noise Reduction Program. Emphasis is given to only the engine noise reduction research and significant accomplishments that were investigated at Technology Readiness Levels ranging from 4 to 6. The Engine Noise Reduction sub-element was divided into four work areas: source noise prediction, model scale tests, engine validation, and active noise control. Highlights from each area include technologies for higher bypass ratio turbofans, scarf inlets, forward-swept fans, swept and leaned stators, chevron/tabbed nozzles, advanced noise prediction analyses, and active noise control for fans. Finally, an industry perspective is given from General Electric Aircraft Engines showing how these technologies are being applied to commercial products. This publication contains only presentation vu-graphs from an invited lecture given at the 41st AIAA Aerospace Sciences Meeting, January 6-9, 2003.

Guidelines for Implementation of an Advanced Outage Control Center to Improve Outage Coordination, Problem Resolution, and Outage Risk Management

DOE Office of Scientific and Technical Information (OSTI.GOV)

St. Germain, Shawn W.; Farris, Ronald K.; Whaley, April M.

This research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which is a research and development (R&D) program sponsored by Department of Energy (DOE) and performed in close collaboration with industry R&D programs that provide the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. The LWRS program serves to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The purpose of this research is to improve management of nuclear powermore » plant (NPP) outages through the development of an advanced outage control center (AOCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. This technical report for industry implementation outlines methods and considerations for the establishment of an AOCC. This report provides a process for implementation of a change management plan, evaluation of current outage processes, the selection of technology, and guidance for the implementation of the selected technology. Methods are presented for both adoption of technologies within an existing OCC and for a complete OCC replacement, including human factors considerations for OCC design and setup.« less

Process control integration requirements for advanced life support systems applicable to manned space missions

NASA Technical Reports Server (NTRS)

Spurlock, Paul; Spurlock, Jack M.; Evanich, Peggy L.

1991-01-01

An overview of recent developments in process-control technology which might have applications in future advanced life support systems for long-duration space operations is presented. Consideration is given to design criteria related to control system selection and optimization, and process-control interfacing methodology. Attention is also given to current life support system process control strategies, innovative sensors, instrumentation and control, and innovations in process supervision.

Advanced Life Support Research and Technology Development Metric: Fiscal Year 2003

NASA Technical Reports Server (NTRS)

Hanford, A. J.

2004-01-01

This document provides the official calculation of the Advanced Life Support (ALS) Research and Technology Development Metric (the Metric) for Fiscal Year 2003. As such, the values herein are primarily based on Systems Integration, Modeling, and Analysis (SIMA) Element approved software tools or reviewed and approved reference documents. The Metric is one of several measures employed by the National Aeronautics and Space Administration (NASA) to assess the Agency s progress as mandated by the United States Congress and the Office of Management and Budget. Because any measure must have a reference point, whether explicitly defined or implied, the Metric is a comparison between a selected ALS Project life support system and an equivalently detailed life support system using technology from the Environmental Control and Life Support System (ECLSS) for the International Space Station (ISS). More specifically, the Metric is the ratio defined by the equivalent system mass (ESM) of a life support system for a specific mission using the ISS ECLSS technologies divided by the ESM for an equivalent life support system using the best ALS technologies. As defined, the Metric should increase in value as the ALS technologies become lighter, less power intensive, and require less volume. For Fiscal Year 2003, the Advanced Life Support Research and Technology Development Metric value is 1.47 for an Orbiting Research Facility and 1.36 for an Independent Exploration Mission.

Advances in Gammalloy Materials-Processes-Application Technology: Successes, Dilemmas, and Future

NASA Astrophysics Data System (ADS)

Kim, Young-Won; Kim, Sang-Lan

2018-04-01

For the last several years, gamma titanium aluminide ( γ-TiAl)-based alloys, called "gammalloys," in specific alloy-microstructure forms began to be implemented in civil aero-engines as cast or wrought low-pressure turbine (LPT) blades and in select ground vehicle engines as cast turbocharger rotors and wrought exhaust valves. Their operation temperatures are approximately up to 750°C for LPT blades and around 1000°C for turbocharger rotors. This article critically assesses current engineering gammalloys and their limitations and introduces eight strengthening pathways that can be adopted immediately for the development of advanced, higher temperature gammalloys. Intelligent integration of the pathways into the emerging application-specific research and development processes is emphasized as the key to the advancement of the gammalloy technology to the next higher engineering performance levels.

Thermoelectric Energy Conversion Technology for High-Altitude Airships

NASA Technical Reports Server (NTRS)

Choi, Sang H.; Elliott, James R.; King, Glen C.; Park, Yeonjoon; Kim, Jae-Woo; Chu, Sang-Hyon

2011-01-01

The High Altitude Airship (HAA) has various application potential and mission scenarios that require onboard energy harvesting and power distribution systems. The power technology for HAA maneuverability and mission-oriented applications must come from its surroundings, e.g. solar power. The energy harvesting system considered for HAA is based on the advanced thermoelectric (ATE) materials being developed at NASA Langley Research Center. The materials selected for ATE are silicon germanium (SiGe) and bismuth telluride (Bi2Te3), in multiple layers. The layered structure of the advanced TE materials is specifically engineered to provide maximum efficiency for the corresponding range of operational temperatures. For three layers of the advanced TE materials that operate at high, medium, and low temperatures, correspondingly in a tandem mode, the cascaded efficiency is estimated to be greater than 60 percent.

Reading and the New Technologies. Proceedings of the Annual Course and Conference of the United Kingdom Reading Association (21st, Dundee, Scotland, July 23-27, 1984).

ERIC Educational Resources Information Center

Ewing, J. M., Ed.

Divided into three sections, this book presents a selection of papers arising from a conference that focused on the impact of recent technological advancements on the development and teaching of reading. An introduction by J. M. Ewing provides general insight on this topic. Identifying major concerns, the first section includes: "Reading and…

Display technology - Human factors concepts

NASA Astrophysics Data System (ADS)

Stokes, Alan; Wickens, Christopher; Kite, Kirsten

1990-03-01

Recent advances in the design of aircraft cockpit displays are reviewed, with an emphasis on their applicability to automobiles. The fundamental principles of display technology are introduced, and individual chapters are devoted to selective visual attention, command and status displays, foveal and peripheral displays, navigational displays, auditory displays, color and pictorial displays, head-up displays, automated systems, and dual-task performance and pilot workload. Diagrams, drawings, and photographs of typical displays are provided.

NATO Standardization and Licensing Policy-Exploratory Phase. Volume 3. Supplement

DTIC Science & Technology

1976-11-30

Aerospatiale will perform at least half the production of this aircraft.* The concept involves a relatively light- weight advanced interceptor with...a ratio of total thrust to takeoff gross weight of about unity. The technology of the aircraft calls for the use of carbon fiber in selected...presenting a system with operating temperatures, pressure ratios, and thrust-to- weight ratios roughly comparable to U.S. technology. The

Developing Trust in Virtual Teams

ERIC Educational Resources Information Center

Germain, Marie-Line

2011-01-01

Rapid globalization, advances in technology, flatter organizational structures, synergistic cooperation among firms, and a shift to knowledge work environments have led to the increasing use of virtual teams in organizations. Selecting, training, and socializing employees in virtual teamwork has therefore become an important human resource…

Report on the Development of the Advanced Encryption Standard (AES)

PubMed Central

Nechvatal, James; Barker, Elaine; Bassham, Lawrence; Burr, William; Dworkin, Morris; Foti, James; Roback, Edward

2001-01-01

In 1997, the National Institute of Standards and Technology (NIST) initiated a process to select a symmetric-key encryption algorithm to be used to protect sensitive (unclassified) Federal information in furtherance of NIST’s statutory responsibilities. In 1998, NIST announced the acceptance of 15 candidate algorithms and requested the assistance of the cryptographic research community in analyzing the candidates. This analysis included an initial examination of the security and efficiency characteristics for each algorithm. NIST reviewed the results of this preliminary research and selected MARS, RC™, Rijndael, Serpent and Twofish as finalists. Having reviewed further public analysis of the finalists, NIST has decided to propose Rijndael as the Advanced Encryption Standard (AES). The research results and rationale for this selection are documented in this report. PMID:27500035

Aircraft System Analysis of Technology Benefits to Civil Transport Rotorcraft

NASA Technical Reports Server (NTRS)

Wilkerson, Joseph B.; Smith, Roger L.

2008-01-01

An aircraft systems analysis was conducted to evaluate the net benefits of advanced technologies on two conceptual civil transport rotorcraft, to quantify the potential of future civil rotorcraft to become operationally viable and economically competitive, with the ultimate goal of alleviating congestion in our airways, runways and terminals. These questions are three of many that must be resolved for the successful introduction of civil transport rotorcraft: 1) Can civil transport rotorcraft actually relieve current airport congestion and improve overall air traffic and passenger throughput at busy hub airports? What is that operational scenario? 2) Can advanced technology make future civil rotorcraft economically competitive in scheduled passenger transport? What are those enabling technologies? 3) What level of investment is necessary to mature the key enabling technologies? This study addresses the first two questions, and several others, by applying a systems analysis approach to a broad spectrum of potential advanced technologies at a conceptual level of design. The method was to identify those advanced technologies that showed the most promise and to quantify their benefits to the design, development, production, and operation of future civil rotorcraft. Adjustments are made to sizing data by subject matter experts to reflect the introduction of new technologies that offer improved performance, reduced weight, reduced maintenance, or reduced cost. This study used projected benefits from new, advanced technologies, generally based on research results, analysis, or small-scale test data. The technologies are identified, categorized and quantified in the report. The net benefit of selected advanced technologies is quantified for two civil transport rotorcraft concepts, a Single Main Rotor Compound (SMRC) helicopter designed for 250 ktas cruise airspeed and a Civil Tilt Rotor (CTR) designed for 350 ktas cruise airspeed. A baseline design of each concept was sized for a representative civil passenger transport mission, using current technology. Individual advanced technologies are quantified and applied to resize the aircraft, thereby quantifying the net benefit of that technology to the rotorcraft. Estimates of development cost, production cost and operating and support costs are made with a commercial cost estimating program, calibrated to Boeing products with adjustments for future civil production processes. A cost metric of cash direct operating cost per available seat-mile (DOC ASM) is used to compare the cost benefit of the technologies. The same metric is used to compare results with turboprop operating costs. Reduced engine SFC was the most advantageous advanced technology for both rotorcraft concepts. Structural weight reduction was the second most beneficial technology, followed by advanced drive systems and then by technology for rotorcraft performance. Most of the technologies evaluated in this report should apply similarly to conventional helicopters. The implicit assumption is that resources will become available to mature the technologies for fullscale production aircraft. That assumption is certainly the weak link in any forecast of future possibilities. The analysis serves the purpose of identifying which technologies offer the most potential benefit, and thus the ones that should receive the highest priority for continued development. This study directly addressed the following NASA Subsonic Rotary Wing (SRW) subtopics: SR W.4.8.I.J Establish capability for rotorcraft system analysis and SRW. 4.8.I.4 Conduct limited technology benefit assessment on baseline rotorcraft configurations.

Space radioisotope power source requirements update and technology status

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mondt, J.F.

1998-07-01

The requirements for a space advanced radioisotope power source are based on potential deep space missions being investigated for the NASA Advanced Space Systems Development Program. Since deep space missions have not been approved, updating requirements is a continuos parallel process of designing the spacecraft and the science instruments to accomplish the potential missions and developing the power source technology to meet changing requirements. There are at least two potential missions, Pluto/Kuiper Express and Europa Orbiter, which may require space advanced radioisotope power sources. The Europa Orbiter has been selected as the preferred first potential mission. However the final decisionmore » will depend on the technology readiness of all the subsystems and the project must be able to switch to Pluto Kuiper Express as the first mission as late as the beginning of fiscal year 2000. Therefore the requirements for the power source will cover both potential missions. As the deep space spacecraft design evolves to meet the science requirements and the Alkali Metal Thermal to Electric (AMTEC) technology matures the advanced radioisotope power source design requirements are updated The AMTEC technology developed to date uses stainless steel for the sodium containment material. The higher efficiency required for the space power system dictates that the AMTEC technology must operate at a higher temperature than possible with stainless steel. Therefore refractory materials have been selected as the baseline material for the AMTEC cell. These refractory materials are Nb1Zr for the hot side and Nb1Zr or Nb10Hf1Ti for the cold side. These materials were selected so the AMTEC cell can operate at 1150K to 1350K hot side temperature and 600K to 700K cold side temperature and meet the present power and mass requirements using four to six general purpose heat source modules as the heat source. The new containment materials and brazes will be evaluated as to lifetime, compatibility and performance with the AMTEC beta prime Alumina, the TiN electrodes, the sodium and the molybdenum current collectors. AMTEC cell components and cells will be built with the baseline containment materials and brazes and tested to determine the performance as a function of temperature. These containment materials will be also be tested with all the other AMTEC components to determine acceleration factors needed to predict AMTEC performance degradation and failure as a function of operating time at temperature.« less

Advanced Stirling Duplex Materials Assessment for Potential Venus Mission Heater Head Application

NASA Technical Reports Server (NTRS)

Ritzert, Frank; Nathal, Michael V.; Salem, Jonathan; Jacobson, Nathan; Nesbitt, James

2011-01-01

This report will address materials selection for components in a proposed Venus lander system. The lander would use active refrigeration to allow Space Science instrumentation to survive the extreme environment that exists on the surface of Venus. The refrigeration system would be powered by a Stirling engine-based system and is termed the Advanced Stirling Duplex (ASD) concept. Stirling engine power conversion in its simplest definition converts heat from radioactive decay into electricity. Detailed design decisions will require iterations between component geometries, materials selection, system output, and tolerable risk. This study reviews potential component requirements against known materials performance. A lower risk, evolutionary advance in heater head materials could be offered by nickel-base superalloy single crystals, with expected capability of approximately 1100C. However, the high temperature requirements of the Venus mission may force the selection of ceramics or refractory metals, which are more developmental in nature and may not have a well-developed database or a mature supporting technology base such as fabrication and joining methods.

Status Report on the First Round of the Development of the Advanced Encryption Standard

PubMed Central

Nechvatal, James; Barker, Elaine; Dodson, Donna; Dworkin, Morris; Foti, James; Roback, Edward

1999-01-01

In 1997, the National Institute of Standards and Technology (NIST) initiated a process to select a symmetric-key encryption algorithm to be used to protect sensitive (unclassified) Federal information in furtherance of NIST’s statutory responsibilities. In 1998, NIST announced the acceptance of 15 candidate algorithms and requested the assistance of the cryptographic research community in analyzing the candidates. This analysis included an initial examination of the security and efficiency characteristics for each algorithm. NIST has reviewed the results of this research and selected five algorithms (MARS, RC6™, Rijndael, Serpent and Twofish) as finalists. The research results and rationale for the selection of the finalists are documented in this report. The five finalists will be the subject of further study before the selection of one or more of these algorithms for inclusion in the Advanced Encryption Standard.

Preface to the special issue of Solid State Electronics EUROSOI/ULIS 2017

NASA Astrophysics Data System (ADS)

Nassiopoulou, Androula G.

2018-05-01

This special issue is devoted to selected papers presented at the EuroSOI-ULIS2017 international conference, held in Athens on 3-5 April 2017. EuroSOI-ULIS2017 Conference was mainly devoted to Si devices, which constitute the basic building blocks of any microelectronic circuit. It included papers on advanced Si technologies, novel nanoscale devices, advanced electronic materials and device architectures, mechanisms involved, test structures, substrate materials and technologies, modeling/simulation and characterization. Both CMOS and beyond CMOS devices were presented, covering the More Moore domain, as well as new functionalities in silicon-compatible nanostructures and innovative devices, representing the More than Moore domain (on-chip sensors, biosensors, energy harvesting devices, RF passives, etc.).

Energy efficient transport technology: Program summary and bibliography

NASA Technical Reports Server (NTRS)

Middleton, D. B.; Bartlett, D. W.; Hood, R. V.

1985-01-01

The Energy Efficient Transport (EET) Program began in 1976 as an element of the NASA Aircraft Energy Efficiency (ACEE) Program. The EET Program and the results of various applications of advanced aerodynamics and active controls technology (ACT) as applicable to future subsonic transport aircraft are discussed. Advanced aerodynamics research areas included high aspect ratio supercritical wings, winglets, advanced high lift devices, natural laminar flow airfoils, hybrid laminar flow control, nacelle aerodynamic and inertial loads, propulsion/airframe integration (e.g., long duct nacelles) and wing and empennage surface coatings. In depth analytical/trade studies, numerous wind tunnel tests, and several flight tests were conducted. Improved computational methodology was also developed. The active control functions considered were maneuver load control, gust load alleviation, flutter mode control, angle of attack limiting, and pitch augmented stability. Current and advanced active control laws were synthesized and alternative control system architectures were developed and analyzed. Integrated application and fly by wire implementation of the active control functions were design requirements in one major subprogram. Additional EET research included interdisciplinary technology applications, integrated energy management, handling qualities investigations, reliability calculations, and economic evaluations related to fuel savings and cost of ownership of the selected improvements.

Mobile satellite communications technology - A summary of NASA activities

NASA Technical Reports Server (NTRS)

Dutzi, E. J.; Knouse, G. H.

1986-01-01

Studies in recent years indicate that future high-capacity mobile satellite systems are viable only if certain high-risk enabling technologies are developed. Accordingly, NASA has structured an advanced technology development program aimed at efficient utilization of orbit, spectrum, and power. Over the last two years, studies have concentrated on developing concepts and identifying cost drivers and other issues associated with the major technical areas of emphasis: vehicle antennas, speech compression, bandwidth-efficient digital modems, network architecture, mobile satellite channel characterization, and selected space segment technology. The program is now entering the next phase - breadboarding, development, and field experimentation.

Evaluation of Aqua-Ammonia Chiller Technologies and Field Site Installation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zaltash, Abdolreza

2007-09-01

The Naval Facilities Engineering Service Center (NFESC) has sponsored Oak Ridge National Laboratory (ORNL) to review, select, and evaluate advanced, gas-fired, 5-ton, aqua-ammonia, chiller technologies. The selection criteria was that units have COP values of 0.67 or better at Air-conditioning and Refrigeration Institute (ARI) 95 F outdoor rating conditions, an active refrigerant flow control, and a variable-speed condenser fan. These features are expected to allow these units to operate at higher ambient temperatures (up to the maximum operating temperature of 110 F) with minimal degradation in performance. ORNL evaluated three potential manufacturers of advanced, gas-fired, 5-ton, aqua-ammonia chillers-Robur, Ambian, andmore » Cooling Technologies. Unfortunately, Robur did not meet the COP requirements and Cooling Technologies could not deliver a unit to be tested at the U.S. Department of Energy (DOE)-ORNL environmental chamber testing facility for thermally activated heat pumps. This eliminated these two technologies from further consideration, leaving only the Ambian chillers for evaluation. Two Ambian chillers were evaluated at the DOE-ORNL test facility. Overall these chillers operated well over a wide range of ambient conditions with minimal degradation in performance due to several control strategies used such as a variable speed condenser fan, a modulating burner, and active refrigerant flow control. These Ambian pre-commercial units were selected for installation and field testing at three federal facilities. NFESC worked with ORNL to assist with the site selection for installation and evaluation of these chillers. Two sites (ORNL and Naval Surface Warfare Center [NSWC] Corona) had a single chiller unit installed; and at one site (Naval Amphibious Base [NAB] Little Creek), two 5-ton chillers linked together were installed to provide 10 tons of cooling. A chiller link controller developed under this project was evaluated in the field test at Little Creek.« less

Using System Mass (SM), Equivalent Mass (EM), Equivalent System Mass (ESM) or Life Cycle Mass (LCM) in Advanced Life Support (ALS) Reporting

NASA Technical Reports Server (NTRS)

Jones, Harry

2003-01-01

The Advanced Life Support (ALS) has used a single number, Equivalent System Mass (ESM), for both reporting progress and technology selection. ESM is the launch mass required to provide a space system. ESM indicates launch cost. ESM alone is inadequate for technology selection, which should include other metrics such as Technology Readiness Level (TRL) and Life Cycle Cost (LCC) and also consider perfom.arxe 2nd risk. ESM has proven difficult to implement as a reporting metric, partly because it includes non-mass technology selection factors. Since it will not be used exclusively for technology selection, a new reporting metric can be made easier to compute and explain. Systems design trades-off performance, cost, and risk, but a risk weighted cost/benefit metric would be too complex to report. Since life support has fixed requirements, different systems usually have roughly equal performance. Risk is important since failure can harm the crew, but it is difficult to treat simply. Cost is not easy to estimate, but preliminary space system cost estimates are usually based on mass, which is better estimated than cost. Amass-based cost estimate, similar to ESM, would be a good single reporting metric. The paper defines and compares four mass-based cost estimates, Equivalent Mass (EM), Equivalent System Mass (ESM), Life Cycle Mass (LCM), and System Mass (SM). EM is traditional in life support and includes mass, volume, power, cooling and logistics. ESM is the specifically defined ALS metric, which adds crew time and possibly other cost factors to EM. LCM is a new metric, a mass-based estimate of LCC measured in mass units. SM includes only the factors of EM that are originally measured in mass, the hardware and logistics mass. All four mass-based metrics usually give similar comparisons. SM is by far the simplest to compute and easiest to explain.

Dopant-Free and Carrier-Selective Heterocontacts for Silicon Solar Cells: Recent Advances and Perspectives.

PubMed

Gao, Pingqi; Yang, Zhenhai; He, Jian; Yu, Jing; Liu, Peipei; Zhu, Juye; Ge, Ziyi; Ye, Jichun

2018-03-01

By combining the most successful heterojunctions (HJ) with interdigitated back contacts, crystalline silicon (c-Si) solar cells (SCs) have recently demonstrated a record efficiency of 26.6%. However, such SCs still introduce optical/electrical losses and technological issues due to parasitic absorption/Auger recombination inherent to the doped films and the complex process of integrating discrete p + - and n + -HJ contacts. These issues have motivated the search for alternative new functional materials and simplified deposition technologies, whereby carrier-selective contacts (CSCs) can be formed directly with c-Si substrates, and thereafter form IBC cells, via a dopant-free method. Screening and modifying CSC materials in a wider context is beneficial for building dopant-free HJ contacts with better performance, shedding new light on the relatively mature Si photovoltaic field. In this review, a significant number of achievements in two representative dopant-free hole-selective CSCs, i.e . , poly(3,4-ethylene dioxythiophene):poly(styrenesulfonate)/Si and transition metal oxides/Si, have been systemically presented and surveyed. The focus herein is on the latest advances in hole-selective materials modification, interfacial passivation, contact resistivity, light-trapping structure and device architecture design, etc. By analyzing the structure-property relationships of hole-selective materials and assessing their electrical transport properties, promising functional materials as well as important design concepts for such CSCs toward high-performance SCs have been highlighted.

Dopant‐Free and Carrier‐Selective Heterocontacts for Silicon Solar Cells: Recent Advances and Perspectives

PubMed Central

Yang, Zhenhai; He, Jian; Yu, Jing; Liu, Peipei; Zhu, Juye; Ge, Ziyi; Ye, Jichun

2017-01-01

Abstract By combining the most successful heterojunctions (HJ) with interdigitated back contacts, crystalline silicon (c‐Si) solar cells (SCs) have recently demonstrated a record efficiency of 26.6%. However, such SCs still introduce optical/electrical losses and technological issues due to parasitic absorption/Auger recombination inherent to the doped films and the complex process of integrating discrete p+‐ and n+‐HJ contacts. These issues have motivated the search for alternative new functional materials and simplified deposition technologies, whereby carrier‐selective contacts (CSCs) can be formed directly with c‐Si substrates, and thereafter form IBC cells, via a dopant‐free method. Screening and modifying CSC materials in a wider context is beneficial for building dopant‐free HJ contacts with better performance, shedding new light on the relatively mature Si photovoltaic field. In this review, a significant number of achievements in two representative dopant‐free hole‐selective CSCs, i.e., poly(3,4‐ethylene dioxythiophene):poly(styrenesulfonate)/Si and transition metal oxides/Si, have been systemically presented and surveyed. The focus herein is on the latest advances in hole‐selective materials modification, interfacial passivation, contact resistivity, light‐trapping structure and device architecture design, etc. By analyzing the structure–property relationships of hole‐selective materials and assessing their electrical transport properties, promising functional materials as well as important design concepts for such CSCs toward high‐performance SCs have been highlighted. PMID:29593956

Pattern optimizing verification of self-align quadruple patterning

NASA Astrophysics Data System (ADS)

Yamato, Masatoshi; Yamada, Kazuki; Oyama, Kenichi; Hara, Arisa; Natori, Sakurako; Yamauchi, Shouhei; Koike, Kyohei; Yaegashi, Hidetami

2017-03-01

Lithographic scaling continues to advance by extending the life of 193nm immersion technology, and spacer-type multi-patterning is undeniably the driving force behind this trend. Multi-patterning techniques such as self-aligned double patterning (SADP) and self-aligned quadruple patterning (SAQP) have come to be used in memory devices, and they have also been adopted in logic devices to create constituent patterns in the formation of 1D layout designs. Multi-patterning has consequently become an indispensible technology in the fabrication of all advanced devices. In general, items that must be managed when using multi-patterning include critical dimension uniformity (CDU), line edge roughness (LER), and line width roughness (LWR). Recently, moreover, there has been increasing focus on judging and managing pattern resolution performance from a more detailed perspective and on making a right/wrong judgment from the perspective of edge placement error (EPE). To begin with, pattern resolution performance in spacer-type multi-patterning is affected by the process accuracy of the core (mandrel) pattern. Improving the controllability of CD and LER of the mandrel is most important, and to reduce LER, an appropriate smoothing technique should be carefully selected. In addition, the atomic layer deposition (ALD) technique is generally used to meet the need for high accuracy in forming the spacer film. Advances in scaling are accompanied by stricter requirements in the controllability of fine processing. In this paper, we first describe our efforts in improving controllability by selecting the most appropriate materials for the mandrel pattern and spacer film. Then, based on the materials selected, we present experimental results on a technique for improving etching selectivity.

Next Generation Life Support Project Status

NASA Technical Reports Server (NTRS)

Barta, Daniel J.; Chullen, Cinda; Vega, Leticia; Cox, Marlon R.; Aitchison, Lindsay T.; Lange, Kevin E.; Pensinger, Stuart J.; Meyer, Caitlin E.; Flynn, Michael; Jackson, W. Andrew;

The Public Health Community Platform, Electronic Case Reporting, and the Digital Bridge.

PubMed

Cooney, Mary Ann; Iademarco, Michael F; Huang, Monica; MacKenzie, William R; Davidson, Arthur J

At the intersection of new technology advancements, ever-changing health policy, and fiscal constraints, public health agencies seek to leverage modern technical innovations and benefit from a more comprehensive and cooperative approach to transforming public health, health care, and other data into action. State health agencies recognized a way to advance population health was to integrate public health with clinical health data through electronic infectious disease case reporting. The Public Health Community Platform (PHCP) concept of bidirectional data flow and knowledge management became the foundation to build a cloud-based system connecting electronic health records to public health data for a select initial set of notifiable conditions. With challenges faced and lessons learned, significant progress was made and the PHCP grew into the Digital Bridge, a national governance model for systems change, bringing together software vendors, public health, and health care. As the model and technology advance together, opportunities to advance future connectivity solutions for both health care and public health will emerge.

[Selected Papers of the EDUCOM Annual Conference, October 1981].

ERIC Educational Resources Information Center

Interuniversity Communications Council (EDUCOM), Princeton, NJ.

This collection of 10 papers from the 1981 conference of the Interuniversity Communications Council (EDUCOM) highlights developments in new communications technologies and their impact on higher education, emphasizing computer usage and telecommunications advancements. Three papers analyzing computer applications to higher education focus on the…

Telework Is Coming...Ready or Not!

ERIC Educational Resources Information Center

Meade, Richard D.

1995-01-01

The potential of advancing information and telecommunications technology to transform the workplace in higher education is examined. Demographic, social, and economic trends contributing to this trend and its advantages and disadvantages are also discussed. Suggestions are made for managing the transition to telework, including selection of…

Propulsion opportunities for future commuter aircraft

NASA Technical Reports Server (NTRS)

Strack, W. C.

1982-01-01

Circa 1990 propulsion improvement concepts are discussed for 1000 to 5000 SHP conventional turboprop powerplants including engines, gearboxes, and propellers. Cycle selection, power plant configurations and advanced technology elements are defined and evaluated using average stage length DOC for commuter aircraft as the primary merit criterion.

Health Information Technology Coordination to Support Patient-centered Care Coordination.

PubMed

Steichen, O; Gregg, W

2015-08-13

To select papers published in 2014, illustrating how information technology can contribute to and improve patient-centered care coordination. The two section editors performed a literature review from Medline and Web of Science to select a list of candidate best papers on the use of information technology for patient-centered care coordination. These papers were peer-reviewed by external reviewers and three of them were selected as "best papers". The first selected paper reports a qualitative study exploring the gap between current practices of care coordination in various settings and idealized longitudinal care plans. The second selected paper illustrates several unintended consequences of HIT designed to improve care coordination. The third selected paper shows that advanced analytic techniques in medical informatics can be instrumental in studying patient-centered care coordination. The realization of true patient-centered care coordination is dependent upon a number of factors. Standardization of clinical documentation and HIT interoperability across organization and settings is a critical prerequisite for HIT to support patient-centered care coordination. Enabling patient involvement is an efficient means for goal setting and health information sharing. Additionally, unintended consequences of HIT tools (both positive and negative) must be measured and taken into account for quality improvement.

Unique Systems Analysis Task 7, Advanced Subsonic Technologies Evaluation Analysis

NASA Technical Reports Server (NTRS)

Eisenberg, Joseph D. (Technical Monitor); Bettner, J. L.; Stratton, S.

2004-01-01

To retain a preeminent U.S. position in the aircraft industry, aircraft passenger mile costs must be reduced while at the same time, meeting anticipated more stringent environmental regulations. A significant portion of these improvements will come from the propulsion system. A technology evaluation and system analysis was accomplished under this task, including areas such as aerodynamics and materials and improved methods for obtaining low noise and emissions. Previous subsonic evaluation analyses have identified key technologies in selected components for propulsion systems for year 2015 and beyond. Based on the current economic and competitive environment, it is clear that studies with nearer turn focus that have a direct impact on the propulsion industry s next generation product are required. This study will emphasize the year 2005 entry into service time period. The objective of this study was to determine which technologies and materials offer the greatest opportunities for improving propulsion systems. The goals are twofold. The first goal is to determine an acceptable compromise between the thermodynamic operating conditions for A) best performance, and B) acceptable noise and chemical emissions. The second goal is the evaluation of performance, weight and cost of advanced materials and concepts on the direct operating cost of an advanced regional transport of comparable technology level.

Advanced Stirling Convertor (ASC) Technology Maturation in Preparation for Flight

NASA Technical Reports Server (NTRS)

Wong, Wayne A.; Cornell, Peggy A.

2012-01-01

The Advanced Stirling Convertor (ASC) is being developed by an integrated team of Sunpower and National Aeronautics and Space Administration s (NASA s) Glenn Research Center (GRC). The ASC development, funded by NASA s Science Mission Directorate, started as a technology development effort in 2003 and has since evolved through progressive convertor builds and successful testing to demonstrate high conversion efficiency, low mass, and capability to meet long-life Radioisotope Power System (RPS) requirements. The technology has been adopted by the Department of Energy and Lockheed Martin Space Systems Company s Advanced Stirling Radioisotope Generator (ASRG), which has been selected for potential flight demonstration on Discovery 12. This paper provides an overview of the status of ASC development including the most recent ASC-E2 convertors that have been delivered to GRC and an introduction to the ASC-E3 and ASC flight convertors that Sunpower will build next. The paper also describes the technology maturation and support tasks being conducted at GRC to support ASC and ASRG development in the areas of convertor and generator extended operation, high-temperature materials, heater head life assessment, organics, nondestructive inspection, spring fatigue testing, and other reliability verification tasks.

Structures and materials technology needs for communications and remote sensing spacecraft

NASA Technical Reports Server (NTRS)

Gronet, M. J.; Jensen, G. A.; Hoskins, J. W.

1995-01-01

This report documents trade studies conducted from the perspective of a small spacecraft developer to determine and quantify the structures and structural materials technology development needs for future commercial and NASA small spacecraft to be launched in the period 1999 to 2005. Emphasis is placed on small satellites weighing less than 1800 pounds for two focus low-Earth orbit missions: commercial communications and remote sensing. The focus missions are characterized in terms of orbit, spacecraft size, performance, and design drivers. Small spacecraft program personnel were interviewed to determine their technology needs, and the results are summarized. A systems-analysis approach for quantifying the benefits of inserting advanced state-of-the-art technologies into a current reference, state-of-the-practice small spacecraft design is developed and presented. This approach is employed in a set of abbreviated trade studies to quantify the payoffs of using a subset of 11 advanced technologies selected from the interview results The 11 technology development opportunities are then ranked based on their relative payoff. Based on the strong potential for significant benefits, recommendations are made to pursue development of 8 and the 11 technologies. Other important technology development areas identified are recommended for further study.

Advancements in text-to-speech technology and implications for AAC applications

NASA Astrophysics Data System (ADS)

Syrdal, Ann K.

2003-10-01

Intelligibility was the initial focus in text-to-speech (TTS) research, since it is clearly a necessary condition for the application of the technology. Sufficiently high intelligibility (approximating human speech) has been achieved in the last decade by the better formant-based and concatenative TTS systems. This led to commercially available TTS systems for highly motivated users, particularly the blind and vocally impaired. Some unnatural qualities of TTS were exploited by these users, such as very fast speaking rates and altered pitch ranges for flagging relevant information. Recently, the focus in TTS research has turned to improving naturalness, so that synthetic speech sounds more human and less robotic. Unit selection approaches to concatenative synthesis have dramatically improved TTS quality, although at the cost of larger and more complex systems. This advancement in naturalness has made TTS technology more acceptable to the general public. The vocally impaired appreciate a more natural voice with which to represent themselves when communicating with others. Unit selection TTS does not achieve such high speaking rates as the earlier TTS systems, however, which is a disadvantage to some AAC device users. An important new research emphasis is to improve and increase the range of emotional expressiveness of TTS.

Advanced Technology Composite Fuselage-Structural Performance

NASA Technical Reports Server (NTRS)

Walker, T. H.; Minguet, P. J.; Flynn, B. W.; Carbery, D. J.; Swanson, G. D.; Ilcewicz, L. B.

1997-01-01

Boeing is studying the technologies associated with the application of composite materials to commercial transport fuselage structure under the NASA-sponsored contracts for Advanced Technology Composite Aircraft Structures (ATCAS) and Materials Development Omnibus Contract (MDOC). This report addresses the program activities related to structural performance of the selected concepts, including both the design development and subsequent detailed evaluation. Design criteria were developed to ensure compliance with regulatory requirements and typical company objectives. Accurate analysis methods were selected and/or developed where practical, and conservative approaches were used where significant approximations were necessary. Design sizing activities supported subsequent development by providing representative design configurations for structural evaluation and by identifying the critical performance issues. Significant program efforts were directed towards assessing structural performance predictive capability. The structural database collected to perform this assessment was intimately linked to the manufacturing scale-up activities to ensure inclusion of manufacturing-induced performance traits. Mechanical tests were conducted to support the development and critical evaluation of analysis methods addressing internal loads, stability, ultimate strength, attachment and splice strength, and damage tolerance. Unresolved aspects of these performance issues were identified as part of the assessments, providing direction for future development.

Case Histories of Intense Pulsed Light Phototherapy in Dermatology - the HPPL™ and IFL™ Technologies

PubMed Central

Martella, Alessandro; Raichi, Mauro

2017-01-01

The intense pulsed light (IPL) and laser technologies are widely used for skin rejuvenation and for treating several dermatological disorders such as skin dyschromia and acne, and for non-ablative dermal remodeling of rhytides and hypertrophic scars. Technological evolution is rapid. The High Power Pulsed Light™ [HPPL™] and Incoherent Fast Light™ technologies [IFL™, Novavision Group S.p.A., 20826 Misinto (MB), Italy] are recent innovations in the field of IPL technologies; IFL™ is a further evolution of the already advanced HPPL™ system. The paper presents a selection of case histories of dermatological lesions treated with the HPPL™ and IFL™ technologies. All study materials were appropriately peer-reviewed for ethical problems. PMID:28652908

Crosscutting Technology Development at the Center for Advanced Separation Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher Hull

2009-10-31

The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginiamore » Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium -- Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno - that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/biological extraction; (4) Modeling and control; and (5) Environmental control. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed by category, along with brief abstracts of their aims and objectives.« less

Evaluation of Treatment Technologies for Wastewater from Insensitive Munitions Production. Phase 1: Technology Down-Selection

DTIC Science & Technology

2013-11-01

the AOP reactor according to the target process formulation. Gases were vented to a GAC vessel. ERDC/EL TR-13-20 94 10.2.2 Results and Discussion...destructive and filtration methods such as biological treatment (destructive), chemical reduction (destructive), reverse osmosis (RO)/nano- filtration ... filtration ), and advanced oxidation processes (destructive). A comprehensive evaluation of alternatives relies on a detailed list of criteria, allowing for

New Space Technology Development

NASA Technical Reports Server (NTRS)

Mueller, Rob

2014-01-01

Visitors from Moon Express, a privately funded commercial space company, will be visiting KSC Swamp Works. This presentation includes a high-level introduction to NASA and commercial partnerships, as well as brief background on the moon - what we used to think about it hundreds of years ago, and what we know today with advanced technologies.***This third part being added includes Swamp Works technical capabilities and has a high-level overview of a selection of projects.***

Technological Advances in Stent Therapies: a Year in Review.

PubMed

Raffoul, Jad; Nasir, Ammar; Klein, Andrew J P

2018-04-07

Stent technology has rapidly evolved since the first stainless steel bare metal stents with substantial developments in scaffolding, polymer, drug choice, drug delivery, and elution mechanisms. Most recently, there has been the evolution of bioabsorbable vascular scaffolds, potentially eliminating the need for long-term foreign object retention. These rapid developments have led to an ever-expanding selection of new stents, making the choice of which to use in which patient challenging. Operators must balance potential short- and long-term clinical ramifications, namely stent thrombosis, in-stent restenosis, target lesion revascularization, and target lesion failure. In this review, we hope to provide insight for interventional cardiologists on the details of stent technology and how this impacts outcomes, stent selection, and duration of dual-antiplatelet therapy duration post drug-eluting stent implantation.

Selected technology for the gas industry

NASA Technical Reports Server (NTRS)

1975-01-01

A number of papers were presented at a conference concerned with the application of technical topics from aerospace activities for the gas industry. The following subjects were covered: general future of fossil fuels in America, exploration for fossil and nuclear fuels from orbital altitudes, technology for liquefied gas, safety considerations relative to fires, explosions, and detonations, gas turbomachinery technology, fluid properties, fluid flow, and heat transfer, NASA information and documentation systems, instrumentation and measurement, materials and life prediction, reliability and quality assurance, and advanced energy systems (including synthetic fuels, energy storage, solar energy, and wind energy).

NASA Electronic Parts and Packaging Program

NASA Technical Reports Server (NTRS)

Kayali, Sammy

2000-01-01

NEPP program objectives are to: (1) Access the reliability of newly available electronic parts and packaging technologies for usage on NASA projects through validations, assessments, and characterizations, and the development of test methods/tools; (2)Expedite infusion paths for advanced (emerging) electronic parts and packaging technologies by evaluations of readiness for manufacturability and project usage consideration; (3) Provide NASA projects with technology selection, application, and validation guidelines for electronic parts and packaging hardware and processes; nd (4) Retain and disseminate electronic parts and packaging quality assurance, reliability validations, tools, and availability information to the NASA community.

Advanced automotive diesel engine system study

NASA Technical Reports Server (NTRS)

1983-01-01

A conceptual study of an advanced automotive diesel engine is discussed. The engine concept selected for vehicle installation was a supercharged 1.4 liter, 4 cylinder spark assisted diesel of 14:1 compression ratio. A compounding unit consisting of a Lysholm compressor and expander is connected to the engine crankshaft by a belt drive. The inlet air charge is heated by the expander exhaust gas via a heat exchanger. Four levels of technology achievement on the selected engine concept were evaluated, from state-of-the-art to the ideal case. This resulted in the fuel economy increasing from 53.2 mpg to 81.7 mpg, and the 0-60 mph time decreasing from 17.6 seconds to 10.9 seconds.

Recent Advances in Skin-Inspired Sensors Enabled by Nanotechnology

NASA Astrophysics Data System (ADS)

Loh, Kenneth J.; Azhari, Faezeh

2012-07-01

The highly optimized performance of nature's creations and biological assemblies has inspired the development of their bio-inspired artificial counterparts that can potentially outperform conventional systems. In particular, the skin of humans, animals, and insects exhibits unique functionalities and properties and has subsequently led to active research in developing skin-inspired sensors. This paper presents a summary of selected work related to skin-inspired tactile, distributed strain, and artificial hair cell flow sensors, with a particular focus on technologies enabled by recent advancements in the nanotechnology domain. The purpose is not to present a comprehensive review on this broad subject matter but rather to use selected work to outline the diversity of current research activities.

Monitoring technologies for ocean disposal of radioactive waste

NASA Astrophysics Data System (ADS)

Triplett, M. B.; Solomon, K. A.; Bishop, C. B.; Tyce, R. C.

1982-01-01

The feasibility of using carefully selected subseabed locations to permanently isolate high level radioactive wastes at ocean depths greater than 4000 meters is discussed. Disposal at several candidate subseabed areas is being studied because of the long term geologic stability of the sediments, remoteness from human activity, and lack of useful natural resources. While the deep sea environment is remote, it also poses some significant challenges for the technology required to survey and monitor these sites, to identify and pinpoint container leakage should it occur, and to provide the environmental information and data base essential to determining the probable impacts of any such occurrence. Objectives and technical approaches to aid in the selective development of advanced technologies for the future monitoring of nuclear low level and high level waste disposal in the deep seabed are presented. Detailed recommendations for measurement and sampling technology development needed for deep seabed nuclear waste monitoring are also presented.

Effect of technological advances on cochlear implant performance in adults.

PubMed

Lenarz, Minoo; Joseph, Gert; Sönmez, Hasibe; Büchner, Andreas; Lenarz, Thomas

2011-12-01

To evaluate the effect of technological advances in the past 20 years on the hearing performance of a large cohort of adult cochlear implant (CI) patients. Individual, retrospective, cohort study. According to technological developments in electrode design and speech-processing strategies, we defined five virtual intervals on the time scale between 1984 and 2008. A cohort of 1,005 postlingually deafened adults was selected for this study, and their hearing performance with a CI was evaluated retrospectively according to these five technological intervals. The test battery was composed of four standard German speech tests: Freiburger monosyllabic test, speech tracking test, Hochmair-Schulz-Moser (HSM) sentence test in quiet, and HSM sentence test in 10 dB noise. The direct comparison of the speech perception in postlingually deafened adults, who were implanted during different technological periods, reveals an obvious improvement in the speech perception in patients who benefited from the recent electrode designs and speech-processing strategies. The major influence of technological advances on CI performance seems to be on speech perception in noise. Better speech perception in noisy surroundings is strong proof for demonstrating the success rate of new electrode designs and speech-processing strategies. Standard (internationally comparable) speech tests in noise should become an obligatory part of the postoperative test battery for adult CI patients. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

A Selective Overview of Variable Selection in High Dimensional Feature Space

PubMed Central

Fan, Jianqing

2010-01-01

High dimensional statistical problems arise from diverse fields of scientific research and technological development. Variable selection plays a pivotal role in contemporary statistical learning and scientific discoveries. The traditional idea of best subset selection methods, which can be regarded as a specific form of penalized likelihood, is computationally too expensive for many modern statistical applications. Other forms of penalized likelihood methods have been successfully developed over the last decade to cope with high dimensionality. They have been widely applied for simultaneously selecting important variables and estimating their effects in high dimensional statistical inference. In this article, we present a brief account of the recent developments of theory, methods, and implementations for high dimensional variable selection. What limits of the dimensionality such methods can handle, what the role of penalty functions is, and what the statistical properties are rapidly drive the advances of the field. The properties of non-concave penalized likelihood and its roles in high dimensional statistical modeling are emphasized. We also review some recent advances in ultra-high dimensional variable selection, with emphasis on independence screening and two-scale methods. PMID:21572976

Propulsion/ASME Rocket-Based Combined Cycle Activities in the Advanced Space Transportation Program Office

NASA Technical Reports Server (NTRS)

Hueter, Uwe; Turner, James

1998-01-01

NASA's Office Of Aeronautics and Space Transportation Technology (OASTT) has establish three major coals. "The Three Pillars for Success". The Advanced Space Transportation Program Office (ASTP) at the NASA's Marshall Space Flight Center in Huntsville,Ala. focuses on future space transportation technologies under the "Access to Space" pillar. The Advanced Reusable Technologies (ART) Project, part of ASTP, focuses on the reusable technologies beyond those being pursued by X-33. The main activity over the past two and a half years has been on advancing the rocket-based combined cycle (RBCC) technologies. In June of last year, activities for reusable launch vehicle (RLV) airframe and propulsion technologies were initiated. These activities focus primarily on those technologies that support the year 2000 decision to determine the path this country will take for Space Shuttle and RLV. In February of this year, additional technology efforts in the reusable technologies were awarded. The RBCC effort that was completed early this year was the initial step leading to flight demonstrations of the technology for space launch vehicle propulsion. Aerojet, Boeing-Rocketdyne and Pratt & Whitney were selected for a two-year period to design, build and ground test their RBCC engine concepts. In addition, ASTROX, Pennsylvania State University (PSU) and University of Alabama in Huntsville also conducted supporting activities. The activity included ground testing of components (e.g., injectors, thrusters, ejectors and inlets) and integrated flowpaths. An area that has caused a large amount of difficulty in the testing efforts is the means of initiating the rocket combustion process. All three of the prime contractors above were using silane (SiH4) for ignition of the thrusters. This follows from the successful use of silane in the NASP program for scramjet ignition. However, difficulties were immediately encountered when silane (an 80/20 mixture of hydrogen/silane) was used for rocket ignition.

REVIEW: Restoring standing capabilities with feedback control of functional neuromuscular stimulation following spinal cord injury

PubMed Central

Nataraj, Raviraj; Audu, Musa L.; Triolo, Ronald J.

2017-01-01

This paper reviews the field of feedback control for neuroprosthesis systems that restore advanced standing function to individuals with spinal cord injury. Investigations into closed-loop control of standing by functional neuromuscular stimulation (FNS) have spanned three decades. The ultimate goal for FNS standing control systems is to facilitate hands free standing and enabling the user to perform manual functions at self-selected leaning positions. However, most clinical systems for home usage currently only provide basic upright standing using preprogrammed stimulation patterns. To date, online modulation of stimulation to produce advanced standing functions such as balance against postural disturbances or the ability to assume leaning postures have been limited to simulation and laboratory investigations. While great technological advances have been made in biomechanical sensing and interfaces for neuromuscular stimulation, further progress is still required for finer motor control by FNS. Another major challenge is the development of sophisticated control schemes that produce the necessary postural adjustments, adapt against accelerating muscle fatigue, and consider volitional actions of the intact upper-body of the user. Model-based development for novel control schemes are proven and sensible approaches to prototype and test the basic operating efficacy of potentially complex and multi-faceted control systems. The major considerations for further innovation of such systems are summarized in this paper prior to describing the evolution of closed-loop FNS control of standing from previous works. Finally, necessary emerging technologies to for implementing FNS feedback control systems for standing are identified. These technological advancements include novel electrodes that more completely and selectively activate paralyzed musculature and implantable sensors and stimulation modules for flexible neuroprosthesis system deployment. PMID:28215399

Restoring standing capabilities with feedback control of functional neuromuscular stimulation following spinal cord injury.

PubMed

Nataraj, Raviraj; Audu, Musa L; Triolo, Ronald J

2017-04-01

This paper reviews the field of feedback control for neuroprosthesis systems that restore advanced standing function to individuals with spinal cord injury. Investigations into closed-loop control of standing by functional neuromuscular stimulation (FNS) have spanned three decades. The ultimate goal for FNS standing control systems is to facilitate hands free standing and enabling the user to perform manual functions at self-selected leaning positions. However, most clinical systems for home usage currently only provide basic upright standing using preprogrammed stimulation patterns. To date, online modulation of stimulation to produce advanced standing functions such as balance against postural disturbances or the ability to assume leaning postures have been limited to simulation and laboratory investigations. While great technological advances have been made in biomechanical sensing and interfaces for neuromuscular stimulation, further progress is still required for finer motor control by FNS. Another major challenge is the development of sophisticated control schemes that produce the necessary postural adjustments, adapt against accelerating muscle fatigue, and consider volitional actions of the intact upper-body of the user. Model-based development for novel control schemes are proven and sensible approaches to prototype and test the basic operating efficacy of potentially complex and multi-faceted control systems. The major considerations for further innovation of such systems are summarized in this paper prior to describing the evolution of closed-loop FNS control of standing from previous works. Finally, necessary emerging technologies to for implementing FNS feedback control systems for standing are identified. These technological advancements include novel electrodes that more completely and selectively activate paralyzed musculature and implantable sensors and stimulation modules for flexible neuroprosthesis system deployment. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

Orbit Transfer Rocket Engine Technology Program

DTIC Science & Technology

1993-10-15

3 TASK D - ADVANCED ENGINE STUDY .............................................. 5 Phase I (D.1, D.2 and D. 3 ...34 High Velocity Ratio Diffusing Crossovers (1.2) .............................. 41 Soft Wear Ring Seals (B. 3 and B.5...67 Combustor Coolant Channel Selection (C.2) .................................. 77 Combustor Caloriniiter Experiments (C. 3 , C.A

48 CFR 1852.219-82 - Limitation on subcontracting-STTR program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... performed by the research institution. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval. (End of clause) [71 FR...

48 CFR 1852.219-82 - Limitation on subcontracting-STTR program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... performed by the research institution. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval. (End of clause) [71 FR...

48 CFR 1852.219-82 - Limitation on subcontracting-STTR program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... performed by the research institution. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval. (End of clause) [71 FR...

48 CFR 1852.219-82 - Limitation on subcontracting-STTR program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... performed by the research institution. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval. (End of clause) [71 FR...

48 CFR 1852.219-82 - Limitation on subcontracting-STTR program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... performed by the research institution. Since the selection of R&D contractors is substantially based on the best scientific and technological sources, it is important that the Contractor not subcontract technical or scientific work without the Contracting Officer's advance approval. (End of clause) [71 FR...

[Medical eugenics: a current issue].

PubMed

Testart, J

1998-01-01

The author begins by examining the historical background of eugenics and then ourlines with examples how it has evolved today (gamete donation, embryo selection, etc.). He concludes by discussing possible requirements to prevent the potential misuses of eugenic medicine which might result from recent advances in science and technology.

Does Abstracting Threaten a Sustainable Future?

ERIC Educational Resources Information Center

Grant, Lyle K.

2012-01-01

In abstraction, or conceptual behavior, people discriminate features or properties of their surroundings. This permits people to respond selectively and precisely to specialized features of their environment, which has had many benefits, including steady advances in science and technology. Within psychology, J. R. Kantor and B. F. Skinner…

Semiochemical based management of biting fly management in the US

USDA-ARS?s Scientific Manuscript database

To present a brief summary of recent advances of theories and applied technologies in entomological sciences, which includes selected members of ESA-OCEA’s research and development to students and other professionals in entomological society of America. This also include organizing a meeting of ESA-...

Recent Electric Propulsion Development Activities for NASA Science Missions

NASA Technical Reports Server (NTRS)

Pencil, Eric J.

2009-01-01

(The primary source of electric propulsion development throughout NASA is managed by the In-Space Propulsion Technology Project at the NASA Glenn Research Center for the Science Mission Directorate. The objective of the Electric Propulsion project area is to develop near-term electric propulsion technology to enhance or enable science missions while minimizing risk and cost to the end user. Major hardware tasks include developing NASA s Evolutionary Xenon Thruster (NEXT), developing a long-life High Voltage Hall Accelerator (HIVHAC), developing an advanced feed system, and developing cross-platform components. The objective of the NEXT task is to advance next generation ion propulsion technology readiness. The baseline NEXT system consists of a high-performance, 7-kW ion thruster; a high-efficiency, 7-kW power processor unit (PPU); a highly flexible advanced xenon propellant management system (PMS); a lightweight engine gimbal; and key elements of a digital control interface unit (DCIU) including software algorithms. This design approach was selected to provide future NASA science missions with the greatest value in mission performance benefit at a low total development cost. The objective of the HIVHAC task is to advance the Hall thruster technology readiness for science mission applications. The task seeks to increase specific impulse, throttle-ability and lifetime to make Hall propulsion systems applicable to deep space science missions. The primary application focus for the resulting Hall propulsion system would be cost-capped missions, such as competitively selected, Discovery-class missions. The objective of the advanced xenon feed system task is to demonstrate novel manufacturing techniques that will significantly reduce mass, volume, and footprint size of xenon feed systems over conventional feed systems. This task has focused on the development of a flow control module, which consists of a three-channel flow system based on a piezo-electrically actuated valve concept, as well as a pressure control module, which will regulate pressure from the propellant tank. Cross-platform component standardization and simplification are being investigated through the Standard Architecture task to reduce first user costs for implementing electric propulsion systems. Progress on current hardware development, recent test activities and future plans are discussed.

Advanced protein crystal growth programmatic sensitivity study

NASA Technical Reports Server (NTRS)

1992-01-01

The purpose of this study is to define the costs of various APCG (Advanced Protein Crystal Growth) program options and to determine the parameters which, if changed, impact the costs and goals of the programs and to what extent. This was accomplished by developing and evaluating several alternate programmatic scenarios for the microgravity Advanced Protein Crystal Growth program transitioning from the present shuttle activity to the man tended Space Station to the permanently manned Space Station. These scenarios include selected variations in such sensitivity parameters as development and operational costs, schedules, technology issues, and crystal growth methods. This final report provides information that will aid in planning the Advanced Protein Crystal Growth Program.

Mars Lander/Rover vehicle development: An advanced space design project for USRA and NASA/OAST

NASA Technical Reports Server (NTRS)

1987-01-01

The results of the studies on one particular part of the Mars Lander/Rover (MLR) system are contained: the Balloon Rover. This component vehicle was selected for further research and design because of the lack of technical literature on this subject, as compared to surface rover technology. Landing site selection; balloon system development and deployment; optics and communications; and the payload power supply are described.

Use of computational modeling combined with advanced visualization to develop strategies for the design of crop ideotypes to address food security

DOE PAGES

Christensen, A. J.; Srinivasan, V.; Hart, J. C.; ...

2018-03-17

Sustainable crop production is a contributing factor to current and future food security. Innovative technologies are needed to design strategies that will achieve higher crop yields on less land and with fewer resources. Computational modeling coupled with advanced scientific visualization enables researchers to explore and interact with complex agriculture, nutrition, and climate data to predict how crops will respond to untested environments. These virtual observations and predictions can direct the development of crop ideotypes designed to meet future yield and nutritional demands. This review surveys modeling strategies for the development of crop ideotypes and scientific visualization technologies that have ledmore » to discoveries in “big data” analysis. Combined modeling and visualization approaches have been used to realistically simulate crops and to guide selection that immediately enhances crop quantity and quality under challenging environmental conditions. Lastly, this survey of current and developing technologies indicates that integrative modeling and advanced scientific visualization may help overcome challenges in agriculture and nutrition data as large-scale and multidimensional data become available in these fields.« less

Data handling and visualization for NASA's science programs

NASA Technical Reports Server (NTRS)

Bredekamp, Joseph H. (Editor)

1995-01-01

Advanced information systems capabilities are essential to conducting NASA's scientific research mission. Access to these capabilities is no longer a luxury for a select few within the science community, but rather an absolute necessity for carrying out scientific investigations. The dependence on high performance computing and networking, as well as ready and expedient access to science data, metadata, and analysis tools is the fundamental underpinning for the entire research endeavor. At the same time, advances in the whole range of information technologies continues on an almost explosive growth path, reaching beyond the research community to affect the population as a whole. Capitalizing on and exploiting these advances are critical to the continued success of space science investigations. NASA must remain abreast of developments in the field and strike an appropriate balance between being a smart buyer and a direct investor in the technology which serves its unique requirements. Another key theme deals with the need for the space and computer science communities to collaborate as partners to more fully realize the potential of information technology in the space science research environment.

Use of computational modeling combined with advanced visualization to develop strategies for the design of crop ideotypes to address food security

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christensen, A. J.; Srinivasan, V.; Hart, J. C.

Sustainable crop production is a contributing factor to current and future food security. Innovative technologies are needed to design strategies that will achieve higher crop yields on less land and with fewer resources. Computational modeling coupled with advanced scientific visualization enables researchers to explore and interact with complex agriculture, nutrition, and climate data to predict how crops will respond to untested environments. These virtual observations and predictions can direct the development of crop ideotypes designed to meet future yield and nutritional demands. This review surveys modeling strategies for the development of crop ideotypes and scientific visualization technologies that have ledmore » to discoveries in “big data” analysis. Combined modeling and visualization approaches have been used to realistically simulate crops and to guide selection that immediately enhances crop quantity and quality under challenging environmental conditions. Lastly, this survey of current and developing technologies indicates that integrative modeling and advanced scientific visualization may help overcome challenges in agriculture and nutrition data as large-scale and multidimensional data become available in these fields.« less

Use of computational modeling combined with advanced visualization to develop strategies for the design of crop ideotypes to address food security.

PubMed

Christensen, A J; Srinivasan, Venkatraman; Hart, John C; Marshall-Colon, Amy

2018-05-01

Sustainable crop production is a contributing factor to current and future food security. Innovative technologies are needed to design strategies that will achieve higher crop yields on less land and with fewer resources. Computational modeling coupled with advanced scientific visualization enables researchers to explore and interact with complex agriculture, nutrition, and climate data to predict how crops will respond to untested environments. These virtual observations and predictions can direct the development of crop ideotypes designed to meet future yield and nutritional demands. This review surveys modeling strategies for the development of crop ideotypes and scientific visualization technologies that have led to discoveries in "big data" analysis. Combined modeling and visualization approaches have been used to realistically simulate crops and to guide selection that immediately enhances crop quantity and quality under challenging environmental conditions. This survey of current and developing technologies indicates that integrative modeling and advanced scientific visualization may help overcome challenges in agriculture and nutrition data as large-scale and multidimensional data become available in these fields.

Quantitative optical metrology with CMOS cameras

NASA Astrophysics Data System (ADS)

Furlong, Cosme; Kolenovic, Ervin; Ferguson, Curtis F.

2004-08-01

Recent advances in laser technology, optical sensing, and computer processing of data, have lead to the development of advanced quantitative optical metrology techniques for high accuracy measurements of absolute shapes and deformations of objects. These techniques provide noninvasive, remote, and full field of view information about the objects of interest. The information obtained relates to changes in shape and/or size of the objects, characterizes anomalies, and provides tools to enhance fabrication processes. Factors that influence selection and applicability of an optical technique include the required sensitivity, accuracy, and precision that are necessary for a particular application. In this paper, sensitivity, accuracy, and precision characteristics in quantitative optical metrology techniques, and specifically in optoelectronic holography (OEH) based on CMOS cameras, are discussed. Sensitivity, accuracy, and precision are investigated with the aid of National Institute of Standards and Technology (NIST) traceable gauges, demonstrating the applicability of CMOS cameras in quantitative optical metrology techniques. It is shown that the advanced nature of CMOS technology can be applied to challenging engineering applications, including the study of rapidly evolving phenomena occurring in MEMS and micromechatronics.

Use of computational modeling combined with advanced visualization to develop strategies for the design of crop ideotypes to address food security

PubMed Central

Christensen, A J; Srinivasan, Venkatraman; Hart, John C; Marshall-Colon, Amy

2018-01-01

Abstract Sustainable crop production is a contributing factor to current and future food security. Innovative technologies are needed to design strategies that will achieve higher crop yields on less land and with fewer resources. Computational modeling coupled with advanced scientific visualization enables researchers to explore and interact with complex agriculture, nutrition, and climate data to predict how crops will respond to untested environments. These virtual observations and predictions can direct the development of crop ideotypes designed to meet future yield and nutritional demands. This review surveys modeling strategies for the development of crop ideotypes and scientific visualization technologies that have led to discoveries in “big data” analysis. Combined modeling and visualization approaches have been used to realistically simulate crops and to guide selection that immediately enhances crop quantity and quality under challenging environmental conditions. This survey of current and developing technologies indicates that integrative modeling and advanced scientific visualization may help overcome challenges in agriculture and nutrition data as large-scale and multidimensional data become available in these fields. PMID:29562368

Materials and Structures Research for Gas Turbine Applications Within the NASA Subsonic Fixed Wing Project

NASA Technical Reports Server (NTRS)

Hurst, Janet

2011-01-01

A brief overview is presented of the current materials and structures research geared toward propulsion applications for NASA s Subsonic Fixed Wing Project one of four projects within the Fundamental Aeronautics Program of the NASA Aeronautics Research Mission Directorate. The Subsonic Fixed Wing (SFW) Project has selected challenging goals which anticipate an increasing emphasis on aviation s impact upon the global issue of environmental responsibility. These goals are greatly reduced noise, reduced emissions and reduced fuel consumption and address 25 to 30 years of technology development. Successful implementation of these demanding goals will require development of new materials and structural approaches within gas turbine propulsion technology. The Materials and Structures discipline, within the SFW project, comprise cross-cutting technologies ranging from basic investigations to component validation in laboratory environments. Material advances are teamed with innovative designs in a multidisciplinary approach with the resulting technology advances directed to promote the goals of reduced noise and emissions along with improved performance.

Next-generation sequencing in the clinic: promises and challenges.

PubMed

Xuan, Jiekun; Yu, Ying; Qing, Tao; Guo, Lei; Shi, Leming

2013-11-01

The advent of next generation sequencing (NGS) technologies has revolutionized the field of genomics, enabling fast and cost-effective generation of genome-scale sequence data with exquisite resolution and accuracy. Over the past years, rapid technological advances led by academic institutions and companies have continued to broaden NGS applications from research to the clinic. A recent crop of discoveries have highlighted the medical impact of NGS technologies on Mendelian and complex diseases, particularly cancer. However, the ever-increasing pace of NGS adoption presents enormous challenges in terms of data processing, storage, management and interpretation as well as sequencing quality control, which hinder the translation from sequence data into clinical practice. In this review, we first summarize the technical characteristics and performance of current NGS platforms. We further highlight advances in the applications of NGS technologies towards the development of clinical diagnostics and therapeutics. Common issues in NGS workflows are also discussed to guide the selection of NGS platforms and pipelines for specific research purposes. Published by Elsevier Ireland Ltd.

Genetic technologies and ethics.

PubMed

Ardekani, Ali M

2009-01-01

In the past decade, the human genome has been completely sequenced and the knowledge from it has begun to influence the fields of biological and social sciences in fundamental ways. Identification of about 25000 genes in the human genome is expected to create great benefits in diagnosis and treatment of diseases in the coming years. However, Genetic technologies have also created many interesting and difficult ethical issues which can affect the human societies now and in the future. Application of genetic technologies in the areas of stem cells, cloning, gene therapy, genetic manipulation, gene selection, sex selection and preimplantation diagnosis has created a great potential for the human race to influence and change human life on earth as we know it today. Therefore, it is important for leaders of societies in the modern world to pay attention to the advances in genetic technologies and prepare themselves and those institutions under their command to face the challenges which these new technologies induce in the areas of ethics, law and social policies.

Technology development for the Advanced Technology Large Aperture Space Telescope (ATLAST) as a candidate large UV-Optical-Infrared (LUVOIR) surveyor

NASA Astrophysics Data System (ADS)

Bolcar, Matthew R.; Balasubramanian, Kunjithapatham; Clampin, Mark; Crooke, Julie; Feinberg, Lee; Postman, Marc; Quijada, Manuel; Rauscher, Bernard; Redding, David; Rioux, Norman; Shaklan, Stuart; Stahl, H. Philip; Stahle, Carl; Thronson, Harley

2015-09-01

The Advanced Technology Large Aperture Space Telescope (ATLAST) team has identified five key technologies to enable candidate architectures for the future large-aperture ultraviolet/optical/infrared (LUVOIR) space observatory envisioned by the NASA Astrophysics 30-year roadmap, Enduring Quests, Daring Visions. The science goals of ATLAST address a broad range of astrophysical questions from early galaxy and star formation to the processes that contributed to the formation of life on Earth, combining general astrophysics with direct-imaging and spectroscopy of habitable exoplanets. The key technologies are: internal coronagraphs, starshades (or external occulters), ultra-stable large-aperture telescopes, detectors, and mirror coatings. Selected technology performance goals include: 1x10-10 raw contrast at an inner working angle of 35 milli-arcseconds, wavefront error stability on the order of 10 pm RMS per wavefront control step, autonomous on-board sensing and control, and zero-read-noise single-photon detectors spanning the exoplanet science bandpass between 400 nm and 1.8 μm. Development of these technologies will provide significant advances over current and planned observatories in terms of sensitivity, angular resolution, stability, and high-contrast imaging. The science goals of ATLAST are presented and flowed down to top-level telescope and instrument performance requirements in the context of a reference architecture: a 10-meter-class, segmented aperture telescope operating at room temperature (~290 K) at the sun-Earth Lagrange-2 point. For each technology area, we define best estimates of required capabilities, current state-of-the-art performance, and current Technology Readiness Level (TRL) - thus identifying the current technology gap. We report on current, planned, or recommended efforts to develop each technology to TRL 5.

Technology Development for the Advanced Technology Large Aperture Space Telescope (ATLAST) as a Candidate Large UV-Optical-Infrared (LUVOIR) Surveyor

NASA Technical Reports Server (NTRS)

Bolcar, Matthew R.; Balasubramanian, Kunjithapatha; Clampin, Mark; Crooke, Julie; Feinberg, Lee; Postman, Marc; Quijada, Manuel; Rauscher, Bernard; Redding, David; Rioux, Norman;

The Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource.

PubMed

Gifford, Lida K; Carter, Lester G; Gabanyi, Margaret J; Berman, Helen M; Adams, Paul D

2012-06-01

The Technology Portal of the Protein Structure Initiative Structural Biology Knowledgebase (PSI SBKB; http://technology.sbkb.org/portal/ ) is a web resource providing information about methods and tools that can be used to relieve bottlenecks in many areas of protein production and structural biology research. Several useful features are available on the web site, including multiple ways to search the database of over 250 technological advances, a link to videos of methods on YouTube, and access to a technology forum where scientists can connect, ask questions, get news, and develop collaborations. The Technology Portal is a component of the PSI SBKB ( http://sbkb.org ), which presents integrated genomic, structural, and functional information for all protein sequence targets selected by the Protein Structure Initiative. Created in collaboration with the Nature Publishing Group, the SBKB offers an array of resources for structural biologists, such as a research library, editorials about new research advances, a featured biological system each month, and a functional sleuth for searching protein structures of unknown function. An overview of the various features and examples of user searches highlight the information, tools, and avenues for scientific interaction available through the Technology Portal.

Applications of advanced transport aircraft in developing countries

NASA Technical Reports Server (NTRS)

Gobetz, F. W.; Assarabowski, R. J.; Leshane, A. A.

1978-01-01

Four representative market scenarios were studied to evaluate the relative performance of air-and surface-based transportation systems in meeting the needs of two developing contries, Brazil and Indonesia, which were selected for detailed case studies. The market scenarios were: remote mining, low-density transport, tropical forestry, and large cargo aircraft serving processing centers in resource-rich, remote areas. The long-term potential of various aircraft types, together with fleet requirements and necessary technology advances, is determined for each application.

Component research for future propulsion systems

NASA Technical Reports Server (NTRS)

Walker, C. L.; Weden, G. J.; Zuk, J.

1981-01-01

Factors affecting the helicopter market are reviewed. The trade-offs involving acquisition cost, mission reliability, and life cycle cost are reviewed, including civil and military aspects. The potential for advanced vehicle configurations with substantial improvements in energy efficiency, operating economics, and characteristics to satisfy the demands of the future market are identified. Advanced propulsion systems required to support these vehicle configurations are discussed, as well as the component technology for the engine systems. Considerations for selection of components in areas of economics and efficiency are presented.

Options for reducing carbon dioxide emissions

NASA Astrophysics Data System (ADS)

Rosenfeld, Arthur H.; Price, Lynn

1992-03-01

Improvements in energy efficiency can significantly reduce the annual growth in greenhouse gas emissions. Such improvements occur when energy intensity is reduced; no reduction in energy services is required. Using the concept of ``cost of conserved energy'' to develop conservation supply curves similar to resource supply curves, researchers consistently find that electricity and natural gas savings of nearly 50% of current consumption are possible for U.S. buildings. Such reductions in energy consumption directly reduce emissions of greenhouse gases. To capture these savings, we must continue to develop energy-efficient technologies and strategies. This paper describes three recent energy-efficient technologies that benefitted from energy conservation research and development (R&D) funding: high-frequency ballasts, compact fluorescent lamps, and low-emissivity windows. Other advanced technologies and strategies of spectrally selective windows, superwindows, electrochromic windows, advanced insulation, low-flow showerheads, improved recessed lamp fixtures, whitening surfaces and planting urban trees, daylighting, and thermal energy storage are also discussed.

Advancing Transportation through Vehicle Electrification - PHEV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bazzi, Abdullah; Barnhart, Steven

2014-12-31

FCA US LLC viewed the American Recovery and Reinvestment Act (ARRA) as an historic opportunity to learn about and develop PHEV technologies and create the FCA US LLC engineering center for Electrified Powertrains. The ARRA funding supported FCA US LLC’s light-duty electric drive vehicle and charging infrastructure-testing activities and enabled FCA US LLC to utilize the funding on advancing Plug-in Hybrid Electric Vehicle (PHEV) technologies for production on future programs. FCA US LLC intended to develop the next-generations of electric drive and energy batteries through a properly paced convergence of standards, technology, components and common modules. To support the developmentmore » of a strong, commercially viable supplier base, FCA US LLC also utilized this opportunity to evaluate various designated component and sub-system suppliers. The original proposal of this project was submitted in May 2009 and selected in August 2009. The project ended in December 2014.« less

Evaluation of Advanced Composite Structures Technologies for Application to NASA's Vision for Space Exploration

NASA Technical Reports Server (NTRS)

Tenney, Darrel R.

2008-01-01

AS&M performed a broad assessment survey and study to establish the potential composite materials and structures applications and benefits to the Constellation Program Elements. Trade studies were performed on selected elements to determine the potential weight or performance payoff from use of composites. Weight predictions were made for liquid hydrogen and oxygen tanks, interstage cylindrical shell, lunar surface access module, ascent module liquid methane tank, and lunar surface manipulator. A key part of this study was the evaluation of 88 different composite technologies to establish their criticality to applications for the Constellation Program. The overall outcome of this study shows that composites are viable structural materials which offer from 20% to 40% weight savings for many of the structural components that make up the Major Elements of the Constellation Program. NASA investment in advancing composite technologies for space structural applications is an investment in America's Space Exploration Program.

Advancement and applications of peptide phage display technology in biomedical science.

PubMed

Wu, Chien-Hsun; Liu, I-Ju; Lu, Ruei-Min; Wu, Han-Chung

2016-01-19

Combinatorial phage library is a powerful research tool for high-throughput screening of protein interactions. Of all available molecular display techniques, phage display has proven to be the most popular approach. Screening phage-displayed random peptide libraries is an effective means of identifying peptides that can bind target molecules and regulate their function. Phage-displayed peptide libraries can be used for (i) B-cell and T-cell epitope mapping, (ii) selection of bioactive peptides bound to receptors or proteins, disease-specific antigen mimics, peptides bound to non-protein targets, cell-specific peptides, or organ-specific peptides, and (iii) development of peptide-mediated drug delivery systems and other applications. Targeting peptides identified using phage display technology may be useful for basic research and translational medicine. In this review article, we summarize the latest technological advancements in the application of phage-displayed peptide libraries to applied biomedical sciences.

Arrow-wing supersonic cruise aircraft structural design concepts evaluation. Volume 2: Sections 7 through 11

NASA Technical Reports Server (NTRS)

Sakata, I. F.; Davis, G. W.

1975-01-01

The materials and advanced producibility methods that offer potential structural mass savings in the design of the primary structure for a supersonic cruise aircraft are identified and reported. A summary of the materials and fabrication techniques selected for this analytical effort is presented. Both metallic and composite material systems were selected for application to a near-term start-of-design technology aircraft. Selective reinforcement of the basic metallic structure was considered as the appropriate level of composite application for the near-term design.

In situ fenestrations for the aortic arch and visceral segment: advances and challenges.

PubMed

Riga, Celia V; McWilliams, Richard G; Cheshire, Nicholas J W

2011-09-01

The management of complex aortic pathologies remains a major challenge particularly in the emergency setting. Bespoke fenestrated and branch stent graft technology has shown encouraging short- and mid-term results in selected patients. Despite tremendous technological advances in this field however, factors such as the inherent delay in device manufacturing, anatomical and technical challenges, high degree of planning, and cost hinder the wider applications of minimally invasive endovascular therapy. In situ fenestration of aortic stent grafts is an attractive alternative that eliminates the need for preoperative custom tailoring with the potential to widen the therapeutic options available and to offer a bailout option after inadvertent side branch occlusion. This article summarizes the principles of this technique and discusses its current applications.

The Challenges of Developing a Food System for a Mars Mission

NASA Technical Reports Server (NTRS)

Perchonok, Michele

2007-01-01

A viewgraph describing the food system that NASA is developing for Manned Mars Missions is shown. The topics include: 1) The President's Vision for U.S. Space Exploration -January 14, 2004; 2) Introducing Orion (and Ares); 3) Mercury (1961-1963); 4) Gemini (1965-1966); 5) Apollo (1968-1972); 6) Skylab (1973-1974); 7) Shuttle/Mir (1995-1998); 8) Shuttle (1981-present) International Space Station (2000-present); 9) NASA Stored Food System; 10) Advanced Food Technology; 11) Orion Missions; 12) Orion Challenges; 13) Food Packaging; 14) Mars Mission Assumptions; 15) Planetary Food System Selected Crops; 16) Food Processing Equipment Constraints; 17) Crew Involvement Constraints; 18) Advanced Food Technology Integration; 19) Research Highlights Internal; and 20) Research Highlights External.

Preparing the optics technology to observe the hot universe

NASA Astrophysics Data System (ADS)

Bavdaz, Marcos; Wille, Eric; Wallace, Kotska; Shortt, Brian; Fransen, Sebastiaan; Collon, Maximilien; Ackermann, Marcelo; Vacanti, Giuseppe; Guenther, Ramses; Haneveld, Jeroen; Riekerink, Mark Olde; van Baren, Coen; Kampf, Dirk; Zuknik, Karl-Heinz; Christensen, Finn; Della Monica Ferreira, Desiree; Jakobsen, Anders Clemen; Krumrey, Michael; Müller, Peter; Burwitz, Vadim; Pareschi, Giovanni; Ghigo, Mauro

2014-07-01

With the selection of "The hot and energetic Universe" as science theme for ESA's second large class mission (L2) in the Cosmic Vision programme, work is focusing on the technology preparation for an advanced X-ray observatory. The core enabling technology for the high performance mirror is the Silicon Pore Optics (SPO) [1 to 23], a modular X-ray optics technology, which utilises processes and equipment developed for the semiconductor industry. The paper provides an overview of the programmatic background, the status of SPO technology and gives an outline of the development roadmap and activities undertaken and planned by ESA on optics, coatings [24 to 30] and test facilities [31, 33].

Technical and economic feasibility of integrated video service by satellite

NASA Technical Reports Server (NTRS)

Price, K. M.; Kwan, R. K.; White, L. W.; Garlow, R. K.; Henderson, T. R.

1992-01-01

A feasibility study is presented of utilizing modern satellite technology, or more advanced technology, to create a cost-effective, user-friendly, integrated video service, which can provide videophone, video conference, or other equivalent wideband service on demand. A system is described that permits a user to select a desired audience and establish the required links similar to arranging a teleconference by phone. Attention is given to video standards, video traffic scenarios, satellite system architecture, and user costs.

The New Digital Advance Team--America's K-12 Students Leading the Way to Transforming Learning with 21st Century Technology Tools. Selected National Findings: Speak Up 2008 for Students, Teachers, Parents and Administrators

ERIC Educational Resources Information Center

Project Tomorrow, 2009

2009-01-01

Since 2003, the Speak Up National Research Project has collected and shared the ideas and views of more than 1.5 million K-12 students, teachers, parents and administrators on education and technology. This dataset provides national education leaders and policy makers with the largest collection of authentic, unfiltered stakeholder feedback to…

DARPA Technical Accomplishments. Volume 2. An Historical Review of Selected DARPA Projects

DTIC Science & Technology

1991-04-01

Deputy Director, respectively, of the ARPA Tactical Technology Office, arranged a workshop on tactical systems and technology at the Naval Undersea ...experiment.7 The signal processing for ARTEMIS, and later for LASA, was done by IBM. In the late 1960s the National Academy’s Committee on Undersea Warfare...conducted a Summer Study to review potential advances in undersea surveillance, at the request of the Navy. Among other things this group recommended

Using an Online Portfolio Course in Assessing Students' Work

ERIC Educational Resources Information Center

Yilmaz, Harun; Cetinkaya, Bulent

2007-01-01

New developments and advancements in informational technology bring about several alternative avenues for educators to select in supporting and evaluating their students' learning. Online portfolio is a fairly new technique in this regard. As the online education grows, use of online portfolio becomes more vital for educational programs. At…

Greeting You Online: Selecting Web-Based Conferencing Tools for Instruction in E-Learning Mode

ERIC Educational Resources Information Center

Li, Judy

2014-01-01

Academic distance learning programs have gained popularity and added to the demand for online library services. Librarians are now conducting instruction for distance learning students beyond their traditional work. Technology advancements have enhanced the delivery mode in distance learning across academic disciplines. Online conference tools…

Visible Light-activated TiO2 photocatalytic Films; Synthesis, Characterization and Environmental Application for the Destruction of Microcystin-LR

EPA Science Inventory

Titanium dioxide (TiO2) photocatalysis has become one of the most effective advanced oxidation technologies (AOTs) for the treatment of persistent organic contaminants. To generate hydroxyl radicals, a non-selective, reactive oxidizing species and responsible for the oxidation of...

Proposed Strategy for Selection Against Recessive Genetic Defects Through a Combination of Inbreeding and DNA Markers

USDA-ARS?s Scientific Manuscript database

Recessive genetic defects are currently on the minds of many cattle breeders. The relatively rapid development of diagnostic DNA tests for recessive defects appears to be a major recent technological advancement. However, the attitude of breeders and breed associations toward recessive defects seems...

Whole genome sequencing of elite rice cultivars as a comprehensive information resource for marker assisted selection

USDA-ARS?s Scientific Manuscript database

Current advances in sequencing technologies and bioinformatics allow to determine a nearly complete genomic background of rice, a staple food for the poor people. Consequently, comprehensive databases of variation among thousands of varieties is currently being assembled and released. Proper analysi...

Interfacing with the nervous system: a review of current bioelectric technologies.

PubMed

Sahyouni, Ronald; Mahmoodi, Amin; Chen, Jefferson W; Chang, David T; Moshtaghi, Omid; Djalilian, Hamid R; Lin, Harrison W

2017-10-23

The aim of this study is to discuss the state of the art with regard to established or promising bioelectric therapies meant to alter or control neurologic function. We present recent reports on bioelectric technologies that interface with the nervous system at three potential sites-(1) the end organ, (2) the peripheral nervous system, and (3) the central nervous system-while exploring practical and clinical considerations. A literature search was executed on PubMed, IEEE, and Web of Science databases. A review of the current literature was conducted to examine functional and histomorphological effects of neuroprosthetic interfaces with a focus on end-organ, peripheral, and central nervous system interfaces. Innovations in bioelectric technologies are providing increasing selectivity in stimulating distinct nerve fiber populations in order to activate discrete muscles. Significant advances in electrode array design focus on increasing selectivity, stability, and functionality of implantable neuroprosthetics. The application of neuroprosthetics to paretic nerves or even directly stimulating or recording from the central nervous system holds great potential in advancing the field of nerve and tissue bioelectric engineering and contributing to clinical care. Although current physiotherapeutic and surgical treatments seek to restore function, structure, or comfort, they bear significant limitations in enabling cosmetic or functional recovery. Instead, the introduction of bioelectric technology may play a role in the restoration of function in patients with neurologic deficits.

Technology needs for high-speed rotorcraft

NASA Technical Reports Server (NTRS)

Rutherford, John; Orourke, Matthew; Martin, Christopher; Lovenguth, Marc; Mitchell, Clark

1991-01-01

A study to determine the technology development required for high-speed rotorcraft development was conducted. The study begins with an initial assessment of six concepts capable of flight at, or greater than 450 knots with helicopter-like hover efficiency (disk loading less than 50 pfs). These concepts were sized and evaluated based on measures of effectiveness and operational considerations. Additionally, an initial assessment of the impact of technology advances on the vehicles attributes was made. From these initial concepts a tilt wing and rotor/wing concepts were selected for further evaluation. A more detailed examination of conversion and technology trade studies were conducted on these two vehicles, each sized for a different mission.

Supersonic variable-cycle engines

NASA Technical Reports Server (NTRS)

Willis, E. A.; Welliver, A. D.

1976-01-01

The evolution and current status of selected recent variable cycle engine (VCE) studies are reviewed, and how the results were influenced by airplane requirements is described. Promising VCE concepts are described, their designs are simplified and the potential benefits in terms of aircraft performance are identified. This includes range, noise, emissions, and the time and effort it may require to ensure technical readiness of sufficient depth to satisfy reasonable economic, performance, and environmental constraints. A brief overview of closely related, ongoing technology programs in acoustics and exhaust emissions is also presented. Realistic technology advancements in critical areas combined with well matched aircraft and selected VCE concepts can lead to significantly improved economic and environmental performance relative to first generation SST predictions.

Advanced supersonic propulsion system technology study, phase 2

NASA Technical Reports Server (NTRS)

Allan, R. D.

1975-01-01

Variable cycle engines were identified, based on the mixed-flow low-bypass-ratio augmented turbofan cycle, which has shown excellent range capability in the AST airplane. The best mixed-flow augmented turbofan engine was selected based on range in the AST Baseline Airplane. Selected variable cycle engine features were added to this best conventional baseline engine, and the Dual-Cycle VCE and Double-Bypass VCE were defined. The conventional mixed-flow turbofan and the Double-Bypass VCE were on the subjects of engine preliminary design studies to determine mechanical feasibility, confirm weight and dimensional estimates, and identify the necessary technology considered not yet available. Critical engine components were studied and incorporated into the variable cycle engine design.

Access from Space: A New Perspective on NASA's Space Transportation Technology Requirements and Opportunities

NASA Technical Reports Server (NTRS)

Rasky, Daniel J.

2004-01-01

The need for robust and reliable access from space is clearly demonstrated by the recent loss of the Space Shuttle Columbia; as well as the NASA s goals to get the Shuttle re-flying and extend its life, build new vehicles for space access, produce successful robotic landers and s a q k retrr? llisrions, and maximize the science content of ambitious outer planets missions that contain nuclear reactors which must be safe for re-entry after possible launch aborts. The technology lynch pin of access from space is hypersonic entry systems such the thermal protection system, along with navigation, guidance and control (NG&C). But it also extends to descent and landing systems such as parachutes, airbags and their control systems. Current space access technology maturation programs such as NASA s Next Generation Launch Technology (NGLT) program or the In-Space Propulsion (ISP) program focus on maturing laboratory demonstrated technologies for potential adoption by specific mission applications. A key requirement for these programs success is a suitable queue of innovative technologies and advanced concepts to mature, including mission concepts enabled by innovative, cross cutting technology advancements. When considering space access, propulsion often dominates the capability requirements, as well as the attention and resources. From the perspective of access from space some new cross cutting technology drivers come into view, along with some new capability opportunities. These include new miniature vehicles (micro, nano, and picosats), advanced automated systems (providing autonomous on-orbit inspection or landing site selection), and transformable aeroshells (to maximize capabilities and minimize weight). This paper provides an assessment of the technology drivers needed to meet future access from space mission requirements, along with the mission capabilities that can be envisioned from innovative, cross cutting access from space technology developments.

Imaging Techniques for Clinical Burn Assessment with a Focus on Multispectral Imaging

PubMed Central

Thatcher, Jeffrey E.; Squiers, John J.; Kanick, Stephen C.; King, Darlene R.; Lu, Yang; Wang, Yulin; Mohan, Rachit; Sellke, Eric W.; DiMaio, J. Michael

2016-01-01

Significance: Burn assessments, including extent and severity, are some of the most critical diagnoses in burn care, and many recently developed imaging techniques may have the potential to improve the accuracy of these evaluations. Recent Advances: Optical devices, telemedicine, and high-frequency ultrasound are among the highlights in recent burn imaging advancements. We present another promising technology, multispectral imaging (MSI), which also has the potential to impact current medical practice in burn care, among a variety of other specialties. Critical Issues: At this time, it is still a matter of debate as to why there is no consensus on the use of technology to assist burn assessments in the United States. Fortunately, the availability of techniques does not appear to be a limitation. However, the selection of appropriate imaging technology to augment the provision of burn care can be difficult for clinicians to navigate. There are many technologies available, but a comprehensive review summarizing the tissue characteristics measured by each technology in light of aiding clinicians in selecting the proper device is missing. This would be especially valuable for the nonburn specialists who encounter burn injuries. Future Directions: The questions of when burn assessment devices are useful to the burn team, how the various imaging devices work, and where the various burn imaging technologies fit into the spectrum of burn care will continue to be addressed. Technologies that can image a large surface area quickly, such as thermography or laser speckle imaging, may be suitable for initial burn assessment and triage. In the setting of presurgical planning, ultrasound or optical microscopy techniques, including optical coherence tomography, may prove useful. MSI, which actually has origins in burn care, may ultimately meet a high number of requirements for burn assessment in routine clinical use. PMID:27602255

Optogenetic stimulation of multiwell MEA plates for neural and cardiac applications

NASA Astrophysics Data System (ADS)

Clements, Isaac P.; Millard, Daniel C.; Nicolini, Anthony M.; Preyer, Amanda J.; Grier, Robert; Heckerling, Andrew; Blum, Richard A.; Tyler, Phillip; McSweeney, K. M.; Lu, Yi-Fan; Hall, Diana; Ross, James D.

2016-03-01

Microelectrode array (MEA) technology enables advanced drug screening and "disease-in-a-dish" modeling by measuring the electrical activity of cultured networks of neural or cardiac cells. Recent developments in human stem cell technologies, advancements in genetic models, and regulatory initiatives for drug screening have increased the demand for MEA-based assays. In response, Axion Biosystems previously developed a multiwell MEA platform, providing up to 96 MEA culture wells arrayed into a standard microplate format. Multiwell MEA-based assays would be further enhanced by optogenetic stimulation, which enables selective excitation and inhibition of targeted cell types. This capability for selective control over cell culture states would allow finer pacing and probing of cell networks for more reliable and complete characterization of complex network dynamics. Here we describe a system for independent optogenetic stimulation of each well of a 48-well MEA plate. The system enables finely graded control of light delivery during simultaneous recording of network activity in each well. Using human induced pluripotent stem cell (hiPSC) derived cardiomyocytes and rodent primary neuronal cultures, we demonstrate high channel-count light-based excitation and suppression in several proof-of-concept experimental models. Our findings demonstrate advantages of combining multiwell optical stimulation and MEA recording for applications including cardiac safety screening, neural toxicity assessment, and advanced characterization of complex neuronal diseases.

Research and technology, 1987

NASA Technical Reports Server (NTRS)

1987-01-01

Three broad goals were presented by NASA as a guide to meet the challenges of the future: to advance scientific knowledge of the planet Earth, the solar system, and the universe; to expand human presence beyond the Earth into the solar system; and to strengthen aeronautics research and technology. Near-term and new-generation space transportation and propulsion systems are being analyzed that will assure the nation access to and presence in space. Other key advanced studies include large astronomical observatories, space platforms, scientific and commercial payloads, and systems to enhance operations in Earth orbit. Longer-range studies include systems that would allow humans to explore the Moon and Mars during the next century. Research programs, both to support the many space missions studied or managed by the Center and to advance scientific knowledge in selected areas, involve work in the areas of atmospheric science, earth science, space science (including astrophysics and solar, magnetospheric, and atomic physics), and low-gravity science. Programs and experiment design for flights on the Space Station, free-flying satellites, and the Space Shuttle are being planned. To maintain a leadership position in technology, continued advances in liquid and solid propellant engines, materials and processes; electronic, structural, and thermal investigations; and environmental control are required. Progress during the fiscal year 1987 is discussed.

Recent advances in lithotripsy technology and treatment strategies: A systematic review update

PubMed Central

Elmansy, H.E.; Lingeman, J.E.

2017-01-01

Introduction Shock wave lithotripsy (SWL) is a well – established treatment option for urolithiasis. The technology of SWL has undergone significant changes in an attempt to better optimize the results while reducing failure rates. There are some important limitations that restrict the use of SWL. In this review, we aim to place these advantages and limitations in perspective, assess the current role of SWL, and discuss recent advances in lithotripsy technology and treatment strategies. Methods A comprehensive review was conducted to identify studies reporting outcomes on ESWL. We searched for literature (PubMed, Embase, Medline) that focused on the physics of shock waves, theories of stone disintegration, and studies on optimising shock wave application. Relevant articles in English published since 1980 were selected for inclusion. Results Efficacy has been shown to vary between lithotripters. To maximize stone fragmentation and reduce failure rates, many factors can be optimized. Factors to consider in proper patient selection include skin – to – stone distance and stone size. Careful attention to the rate of shock wave administration, proper coupling of the treatment head to the patient have important influences on the success of lithotripsy. Conclusion Proper selection of patients who are expected to respond well to SWL, as well as attention to the technical aspects of the procedure are the keys to SWL success. Studies aiming to determine the mechanisms of shock wave action in stone breakage have begun to suggest new treatment strategies to improve success rates and safety. PMID:27890653

A flipped mode teaching approach for large and advanced electrical engineering courses

NASA Astrophysics Data System (ADS)

Ravishankar, Jayashri; Epps, Julien; Ambikairajah, Eliathamby

2018-05-01

A fully flipped mode teaching approach is challenging for students in advanced engineering courses, because of demanding pre-class preparation load, due to the complex and analytical nature of the topics. When this is applied to large classes, it brings an additional complexity in terms of promoting the intended active learning. This paper presents a novel selective flipped mode teaching approach designed for large and advanced courses that has two aspects: (i) it provides selective flipping of a few topics, while delivering others in traditional face-to-face teaching, to provide an effective trade-off between the two approaches according to the demands of individual topics and (ii) it introduces technology-enabled live in-class quizzes to obtain instant feedback and facilitate collaborative problem-solving exercises. The proposed approach was implemented for a large fourth year course in electrical power engineering over three successive years and the criteria for selecting between the flipped mode teaching and traditional teaching modes are outlined. Results confirmed that the proposed approach improved both students' academic achievements and their engagement in the course, without overloading them during the teaching period.

Advanced Air Bag Technology Assessment

NASA Technical Reports Server (NTRS)

Phen, R. L.; Dowdy, M. W.; Ebbeler, D. H.; Kim. E.-H.; Moore, N. R.; VanZandt, T. R.

1998-01-01

As a result of the concern for the growing number of air-bag-induced injuries and fatalities, the administrators of the National Highway Traffic Safety Administration (NHTSA) and the National Aeronautics and Space Administration (NASA) agreed to a cooperative effort that "leverages NHTSA's expertise in motor vehicle safety restraint systems and biomechanics with NASAs position as one of the leaders in advanced technology development... to enable the state of air bag safety technology to advance at a faster pace..." They signed a NASA/NHTSA memorandum of understanding for NASA to "evaluate air bag to assess advanced air bag performance, establish the technological potential for improved technology (smart) air bag systems, and identify key expertise and technology within the agency (i.e., NASA) that can potentially contribute significantly to the improved effectiveness of air bags." NASA is committed to contributing to NHTSAs effort to: (1) understand and define critical parameters affecting air bag performance; (2) systematically assess air bag technology state of the art and its future potential; and (3) identify new concepts for air bag systems. The Jet Propulsion Laboratory (JPL) was selected by NASA to respond to the memorandum of understanding by conducting an advanced air bag technology assessment. JPL analyzed the nature of the need for occupant restraint, how air bags operate alone and with safety belts to provide restraint, and the potential hazards introduced by the technology. This analysis yielded a set of critical parameters for restraint systems. The researchers examined data on the performance of current air bag technology, and searched for and assessed how new technologies could reduce the hazards introduced by air bags while providing the restraint protection that is their primary purpose. The critical parameters which were derived are: (1) the crash severity; (2) the use of seat belts; (3) the physical characteristics of the occupants; (4) the proximity of the occupants to the airbag module; (5) the deployment time, which includes the time to sense the need for deployment, the inflator response parameters, the air bag response, and the reliability of the air bag. The requirements for an advanced air bag technology is discussed. These requirements includes that the system use information related to: (1) the crash severity; (2) the status of belt usage; (3) the occupant category; and (4) the proximity to the air bag to adjust air bag deployment. The parameters for the response of the air bag are: (1) deployment time; (2) inflator parameters; and (3) air bag response and reliability. The state of occupant protection advanced technology is reviewed. This review includes: the current safety restraint systems, and advanced technology characteristics. These characteristics are summarized in a table, which has information regarding the technology item, the potential, and an date of expected utilization. The use of technology and expertise at NASA centers is discussed. NASA expertise relating to sensors, computing, simulation, propellants, propulsion, inflatable systems, systems analysis and engineering is considered most useful. Specific NASA technology developments, which were included in the study are: (1) a capacitive detector; (2) stereoscopic vision system; (3) improved crash sensors; (4) the use of the acoustic signature of the crash to determine crash severity; and (5) the use of radar antenna for pre-crash sensing. Information relating to injury risk assessment is included, as is a summary of the areas of the technology which requires further development.

Exploration Laboratory Analysis

NASA Technical Reports Server (NTRS)

Krihak, M.; Ronzano, K.; Shaw, T.

2016-01-01

The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the availability of inflight laboratory analysis instrumentation has been identified as an essential capability for manned exploration missions. Since a single, compact space-ready laboratory analysis capability to perform all exploration clinical measurements is not commercially available, the ELA project objective is to demonstrate the feasibility of emerging operational and analytical capability as a biomedical diagnostics precursor to long duration manned exploration missions. The initial step towards ground and flight demonstrations in fiscal year (FY) 2015 was the down selection of platform technologies for demonstrations in the space environment. The technologies selected included two Small Business Innovation Research (SBIR) performers: DNA Medicine Institutes rHEALTH X and Intelligent Optical Systems later flow assays combined with Holomics smartphone analyzer. The selection of these technologies were based on their compact size, breadth of analytical capability and favorable ability to process fluids in a space environment, among several factors. These two technologies will be advanced to meet ground and flight demonstration success criteria and requirements that will be finalized in FY16. Also, the down selected performers will continue the technology development phase towards meeting prototype deliverables in either late 2016 or 2017.

Review of the Tri-Agency Space Nuclear Reactor Power System Technology Program

NASA Technical Reports Server (NTRS)

Ambrus, J. H.; Wright, W. E.; Bunch, D. F.

1984-01-01

The Space Nuclear Reactor Power System Technology Program designated SP-100 was created in 1983 by NASA, the U.S. Department of Defense, and the Defense Advanced Research Projects Agency. Attention is presently given to the development history of SP-100 over the course of its first year, in which it has been engaged in program objectives' definition, the analysis of civil and military missions, nuclear power system functional requirements' definition, concept definition studies, the selection of primary concepts for technology feasibility validation, and the acquisition of initial experimental and analytical results.

An overview of telemedicine.

PubMed

Baquet, C R

1997-01-01

Greater attention has been given recently to information technology and telecommunication reforms and their use for the improvement of health care service delivery. Broadly defined, telemedicine is the use of advanced telecommunications technologies for the purposes of making diagnoses, conducting research, transferring patient data, and/or improving disease management and treatment in remote areas. The emphasis is on use of telecommunications technologies at remote sites. This article provides a brief overview of telemedicine, its potential clinical applications, and the various benefits and leading issues surrounding it. It also describes selected telemedicine projects conducted at the University of Maryland School of Medicine in Baltimore.

Evidence Gaps in the Use of Spinal Cord Stimulation for Treating Chronic Spine Conditions.

PubMed

Provenzano, David A; Amirdelfan, Kasra; Kapural, Leonardo; Sitzman, B Todd

2017-07-15

A review of literature. The aim of this study was to define and explore the current evidence gaps in the use of spinal cord stimulation (SCS) for treating chronic spine conditions. Although over the last 40 years SCS therapy has undergone significant technological advancements, evidence gaps still exist. A literature review was conducted to define current evidence gaps for the use of SCS. Areas of focus included 1) treatment of cervical spine conditions, 2) treatment of lumbar spine conditions, 3) technological advancement and device selection, 4) appropriate patient selection, 5) the ability to curb pharmacological treatment, and 6) methods to prolong efficacy over time. New SCS strategies using advanced waveforms are explored. The efficacy, safety, and cost-effectiveness of traditional SCS for chronic pain conditions are well-established. Evidence gaps do exist. Recently, advancement in waveforms and programming parameters have allowed for paresthesia-reduced/free stimulation that in specific clinical areas may improve clinical outcomes. New waveforms such as 10-kHz high-frequency have resulted in an improvement in back coverage. To date, clinical efficacy data are more prevalent for the treatment of painful conditions originating from the lumbar spine in comparison to the cervical spine. Evidence gaps still exist that require appropriate study designs with long-term follow-up to better define and improve the use of this therapy for the treatment of chronic spine pain in both the cervical and lumbar regions. N/A.

Electronic health indicators in the selected countries: Are these indicators the best?

PubMed Central

Afshari, Somaye; Khorasani, Elahe; Yarmohammadian, Mohammad Hossein; Atighechian, Golrokh; Darab, Mohsen Ghaffari

2013-01-01

Background: Many changes have been made in different sciences by developing and advancing information and communication technology in last two decades. E-health is a very broad term that includes many different activities related to the use of electronic devices, software as well as hardware in health organizations. Aims: The aim of this study is comparing electronic health indicators in the selected countries and discussion on the best indicators. Settings and Design: This study has chosen 12 countries randomly based on the regional division of the WHO. The relevant numbers of health indicators and general indicators and information technology indicators are extracted of these countries. We use data from the Bitarf's comparative study, which is conducted by the Iranian Supreme Council of Information Technology in 2007. Materials and Methods: By using Pearson correlation test, the relations between health general indicators and IT indicators are studied. Statistical Analysis Used: Data was analyzed based on the research objectives using SPSS software and in accordance with research questions Pearson correlation test were used. Results: The findings show that there is a positive relation between indicators related to IT and “Total per capita health, healthy life expectancy, percent literacy”. Furthermore, there is a mutual relation between IT indicators and “mortality indicator”. Conclusion: This study showed differences between selective indicators among different countries. The modern world, with its technological advances, is not powerless in the face of these geographic and health disparity challenges. Researchers must not rely on the available indicators. They must consider indicators like e-business companies, electronic data internet, medical supplies, health electronic record, health information system, etc., In future, continuous studies in this field, to provide the exact and regular reports of amount of using of these indicators through different countries must be necessary. PMID:24083281

Electronic health indicators in the selected countries: Are these indicators the best?

PubMed

Afshari, Somaye; Khorasani, Elahe; Yarmohammadian, Mohammad Hossein; Atighechian, Golrokh; Darab, Mohsen Ghaffari

2013-01-01

Many changes have been made in different sciences by developing and advancing information and communication technology in last two decades. E-health is a very broad term that includes many different activities related to the use of electronic devices, software as well as hardware in health organizations. The aim of this study is comparing electronic health indicators in the selected countries and discussion on the best indicators. This study has chosen 12 countries randomly based on the regional division of the WHO. The relevant numbers of health indicators and general indicators and information technology indicators are extracted of these countries. We use data from the Bitarf's comparative study, which is conducted by the Iranian Supreme Council of Information Technology in 2007. By using Pearson correlation test, the relations between health general indicators and IT indicators are studied. Data was analyzed based on the research objectives using SPSS software and in accordance with research questions Pearson correlation test were used. The findings show that there is a positive relation between indicators related to IT and "Total per capita health, healthy life expectancy, percent literacy". Furthermore, there is a mutual relation between IT indicators and "mortality indicator". This study showed differences between selective indicators among different countries. The modern world, with its technological advances, is not powerless in the face of these geographic and health disparity challenges. Researchers must not rely on the available indicators. They must consider indicators like e-business companies, electronic data internet, medical supplies, health electronic record, health information system, etc., In future, continuous studies in this field, to provide the exact and regular reports of amount of using of these indicators through different countries must be necessary.

Tissue Engineering and Regenerative Medicine 2017: A Year in Review.

PubMed

Park, Kyung Min; Shin, Young Min; Kim, Kyobum; Shin, Heungsoo

2018-04-26

In 2017, a new paradigm change caused by artificial intelligence and big data analysis resulted in innovation in each field of science and technology, and also significantly influenced progress in tissue engineering and regenerative medicine (TERM). TERM has continued to make technological advances based on interdisciplinary approaches and has contributed to the overall field of biomedical technology, including cancer biology, personalized medicine, development biology, and cell-based therapeutics. While researchers are aware that there is still a long way to go until TERM reaches the ultimate goal of patient treatment through clinical translation, the rapid progress in convergence studies led by technological improvements in TERM has been encouraging. In this review, we highlighted the significant advances made in TERM in 2017 (with an overlap of 5 months in 2016). We identified major progress in TERM in a manner similar to previous reviews published in the last few years. In addition, we carefully considered all four previous reviews during the selection process and chose main themes that minimize the duplication of the topics. Therefore, we have identified three areas that have been the focus of most journal publications in the TERM community in 2017: (i) advanced biomaterials and three-dimensional (3D) cell printing, (ii) exosomes as bioactive agents for regenerative medicine, and (iii) 3D culture in regenerative medicine.

Circulating Tumor Cells: Moving Biological Insights into Detection

PubMed Central

Chen, Lichan; Bode, Ann M; Dong, Zigang

2017-01-01

Circulating tumor cells (CTCs) have shown promising potential as liquid biopsies that facilitate early detection, prognosis, therapeutic target selection and monitoring treatment response. CTCs in most cancer patients are low in abundance and heterogeneous in morphological and phenotypic profiles, which complicate their enrichment and subsequent characterization. Several methodologies for CTC enrichment and characterization have been developed over the past few years. However, integrating recent advances in CTC biology into these methodologies and the selection of appropriate enrichment and characterization methods for specific applications are needed to improve the reliability of CTC biopsies. In this review, we summarize recent advances in the studies of CTC biology, including the mechanisms of their generation and their potential forms of existence in blood, as well as the current CTC enrichment technologies. We then critically examine the selection of methods for appropriately enriching CTCs for further investigation of their clinical applications. PMID:28819450

Immunogenomics of gastrointestinal nematode infection in ruminants - breeding for resistance to produce food sustainably and safely.

PubMed

Sweeney, T; Hanrahan, J P; Ryan, M T; Good, B

2016-09-01

Gastrointestinal nematode (GIN) infection of ruminants represents a major health and welfare challenge for livestock producers worldwide. The emergence of anthelmintic resistance in important GIN species and the associated animal welfare concerns have stimulated interest in the development of alternative and more sustainable strategies aimed at the effective management of the impact of GINs. These integrative strategies include selective breeding using genetic/genomic tools, grazing management, biological control, nutritional supplementation, vaccination and targeted selective treatment. In this review, the logic of selecting for "resistance" to GIN infection as opposed to "resilience" or "tolerance" is discussed. This is followed by a review of the potential application of immunogenomics to genetic selection for animals that have the capacity to withstand the impact of GIN infection. Advances in relevant genomic technologies are highlighted together with how these tools can be advanced to support the integration of immunogenomic information into ruminant breeding programmes. © 2016 John Wiley & Sons Ltd.

Achievement, motivation, and educational choices: A longitudinal study of expectancy and value using a multiplicative perspective.

PubMed

Guo, Jiesi; Parker, Philip D; Marsh, Herbert W; Morin, Alexandre J S

2015-08-01

Drawing on the expectancy-value model, the present study explored individual and gender differences in university entry and selection of educational pathway (e.g., science, technology, engineering, and mathematics [STEM] course selection). In particular, we examined the multiplicative effects of expectancy and task values on educational outcomes during the transition into early adulthood. Participants were from a nationally representative longitudinal sample of 15-year-old Australian youths (N = 10,370). The results suggest that (a) both math self-concept and intrinsic value interact in predicting advanced math course selection, matriculation results, entrance into university, and STEM fields of study; (b) prior reading achievement has negative effects on advanced math course selection and STEM fields through math motivational beliefs; and (c) gender differences in educational outcomes are mediated by gender differences in motivational beliefs and prior academic achievement, while the processes underlying choice of educational pathway were similar for males and females. (c) 2015 APA, all rights reserved).

Development vs. Deployment: How Mature Should a Technology be Before it is Considered for Inclusion in an Acquisition Program?

DTIC Science & Technology

2007-04-30

surface combatant. Take, for instance, the tumblehome hull design of the new Zumwalt-class destroyer. If some critical issues were to arise with the ...more aggressive target is selected, there will be a greater increase in capability for each new system deployed. However, the expected duration of...push for the most advanced technology they can get into each new system. • This behavior exacerbates the problem and leads to even longer acquisition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mutanen, K.I.

Development of fluidized bed combustion (FBC) was started both in North America and in Europe in the 1960`s. In Europe and especially in Scandinavia the major driving force behind the development was the need to find new more efficient technologies for utilization of low-grade fuels like different biomasses and wastes. Both bubbling fluidized bed (BFB) and circulating fluidized bed (CFB) technologies were under intensive R&D,D efforts and have now advanced to dominating role in industrial and district heating power plant markets in Europe. New advanced CFB designs are now entering the markets. In North America and especially in the USmore » the driving force behind the FBC development was initially the need to utilize different types of coals in a more efficient and environmentally acceptable way. The present and future markets seem to be mainly in biomass and multifuel applications where there is benefit from high combustion efficiency, high fuel flexibility and low emissions such as in the pulp and paper industry. The choice between CFB technology and BFB technology is based on selected fuels, emission requirements, plant size and on technical and economic feasibility. Based on Scandinavian experience there is vast potential in the North American industry to retrofit existing oil fired, pulverized coal fired, chemical recovery or grate fired boilers with FBC systems or to build a new FBC based boiler plant. This paper will present the status of CFB technologies and will compare technical and economic feasibility of CFB technology to CFB technology to BFB and also to other combustion methods. Power plant projects that are using advanced CFB technology e.g. Ahlstrom Pyroflow Compact technology for biomass firing and co-firing of biomass with other fuels will also be introduced.« less

Advanced Rotorcraft Transmission (ART) program-Boeing helicopters status report

NASA Technical Reports Server (NTRS)

Lenski, Joseph W., Jr.; Valco, Mark J.

1991-01-01

The Advanced Rotorcraft Transmission (ART) program is structured to incorporate key emerging material and component technologies into an advanced rotorcraft transmission with the intention of making significant improvements in the state of the art (SOA). Specific objectives of ART are: (1) Reduce transmission weight by 25 pct.; (2) Reduce transmission noise by 10 dB; and (3) Improve transmission life and reliability, while extending Mean Time Between Removal to 5000 hr. Boeing selected a transmission sized for the Tactical Tilt Rotor (TTR) aircraft which meets the Future Air Attack Vehicle (FAVV) requirements. Component development testing will be conducted to evaluate the high risk concepts prior to finalizing the advanced transmission configuration. The results of tradeoff studies and development test which were completed are summarized.

Role of long-term mechanical circulatory support in patients with advanced heart failure.

PubMed

Stokes, M B; Bergin, P; McGiffin, D

2016-05-01

Advanced heart failure represents a small proportion of patients with heart failure that possess high-risk features associated with high hospital readmission rates, significant functional impairment and mortality. Identification of those who have progressed to, or are near a state of advanced heart failure should prompt referral to a service that offers therapies in mechanical circulatory support (MCS) and cardiac transplantation. MCS has grown as a management strategy in the care of these patients, most commonly as a bridge to cardiac transplantation. The predominant utilisation of MCS is implantation of left ventricular assist devices (LVAD), which have evolved significantly in their technology and application over the past 15-20 years. The technology has evolved to such an extent that Destination Therapy is now being utilised as a strategy in management of advanced heart failure in appropriately selected patients. Complication rates have decreased with VAD implantation, but remain a significant consideration in the decision to implant a device, and in the follow up of these patients. © 2016 Royal Australasian College of Physicians.

Current state and future direction of computer systems at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Rogers, James L. (Editor); Tucker, Jerry H. (Editor)

1992-01-01

Computer systems have advanced at a rate unmatched by any other area of technology. As performance has dramatically increased there has been an equally dramatic reduction in cost. This constant cost performance improvement has precipitated the pervasiveness of computer systems into virtually all areas of technology. This improvement is due primarily to advances in microelectronics. Most people are now convinced that the new generation of supercomputers will be built using a large number (possibly thousands) of high performance microprocessors. Although the spectacular improvements in computer systems have come about because of these hardware advances, there has also been a steady improvement in software techniques. In an effort to understand how these hardware and software advances will effect research at NASA LaRC, the Computer Systems Technical Committee drafted this white paper to examine the current state and possible future directions of computer systems at the Center. This paper discusses selected important areas of computer systems including real-time systems, embedded systems, high performance computing, distributed computing networks, data acquisition systems, artificial intelligence, and visualization.

Application of Taguchi methods to dual mixture ratio propulsion system optimization for SSTO vehicles

NASA Technical Reports Server (NTRS)

Stanley, Douglas O.; Unal, Resit; Joyner, C. R.

1992-01-01

The application of advanced technologies to future launch vehicle designs would allow the introduction of a rocket-powered, single-stage-to-orbit (SSTO) launch system early in the next century. For a selected SSTO concept, a dual mixture ratio, staged combustion cycle engine that employs a number of innovative technologies was selected as the baseline propulsion system. A series of parametric trade studies are presented to optimize both a dual mixture ratio engine and a single mixture ratio engine of similar design and technology level. The effect of varying lift-off thrust-to-weight ratio, engine mode transition Mach number, mixture ratios, area ratios, and chamber pressure values on overall vehicle weight is examined. The sensitivity of the advanced SSTO vehicle to variations in each of these parameters is presented, taking into account the interaction of each of the parameters with each other. This parametric optimization and sensitivity study employs a Taguchi design method. The Taguchi method is an efficient approach for determining near-optimum design parameters using orthogonal matrices from design of experiments (DOE) theory. Using orthogonal matrices significantly reduces the number of experimental configurations to be studied. The effectiveness and limitations of the Taguchi method for propulsion/vehicle optimization studies as compared to traditional single-variable parametric trade studies is also discussed.

Alternative Fuels Data Center: Widgets

Science.gov Websites

Efficiency and Renewable Energy Get Widget Code × Widget Code Select All Close Vehicle Cost Calculator Share a tool to calculate annual fuel cost and greenhouse gas emissions for alternative fuel and advanced technology vehicles. Vehicle Cost Calculator Choose a vehicle to compare fuel cost and emissions with a

Selected Papers from the National Conference on College Teaching and Learning (6th, Jacksonville, Florida, April 5-8, 1995).

ERIC Educational Resources Information Center

Chambers, Jack A., Ed.

This collection of 18 papers covers four broad areas of teaching and learning in higher education: innovative college teaching/learning strategies; effective classroom research/assessment activities; advanced classroom technology; and developing teaching and learning centers. Titles include: (1) "African American Students' Perceptions of…

The Dichotomous Relationship between Personality Traits and Repatriation Decisions by Information Technology Workers

ERIC Educational Resources Information Center

Pearson, Marcia L. Y.

2013-01-01

Researchers have consistently documented high turnover rates among repatriated workers after overseas assignments, mainly due to post-repatriation concerns about career advancement, compensation reduction, subsequent use of overseas experience, and job security. What is unknown is a method to alleviate this problem by selecting the types of…

MGIS: Managing banana (Musa spp.) genetic resources information and high-throughput genotyping data

USDA-ARS?s Scientific Manuscript database

Unraveling genetic diversity held in genebanks on a large scale is underway, due to the advances in Next-generation sequence-based technologies that produce high-density genetic markers for a large number of samples at low cost. Genebank users should be in a position to identify and select germplasm...

The First NREL Conference on thermophotovoltaic generation of electricity: Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-08-01

This collection of abstracts from the July 1994 meeting contains various information on thermophotovoltaic (TPV) conversion and converters. Discussed topics include: the current status of TPV conversion, TPV tutorials, heat source and emitter technologies, advanced TPV devices, selective emitter theory and practice, programmatic and systems issues, device fundamentals, and device and material characterization.

Managing Complex Distance Education Projects in a Telework Environment

ERIC Educational Resources Information Center

Ally, Mohamed; Cleveland-Innes, Marti; Wiseman, Colin

2010-01-01

The advances of communication technologies have allowed professionals to work on distance education projects in a telework environment. Managers of these projects must have the skills to manage the projects from a distance. They must be able to select the appropriate team members to work on the project, orient team members, and monitor team…

An Ethnographic Approach to Syllabus Design: A Case Study of the Indian Institute of Science, Bangalore.

ERIC Educational Resources Information Center

Ramani, Esther; And Others

1988-01-01

Argues for an ethnographic reorientation to needs analysis and syllabus design in English for specific purposes in advanced postgraduate centers of science and technology. The seven-stage framework (specify learners, analyze needs, specify enabling objectives, select materials, identify teaching/learning activities, evaluate, and revise) used to…

Recent advances in understanding the role of nutrition in human genome evolution.

PubMed

Ye, Kaixiong; Gu, Zhenglong

2011-11-01

Dietary transitions in human history have been suggested to play important roles in the evolution of mankind. Genetic variations caused by adaptation to diet during human evolution could have important health consequences in current society. The advance of sequencing technologies and the rapid accumulation of genome information provide an unprecedented opportunity to comprehensively characterize genetic variations in human populations and unravel the genetic basis of human evolution. Series of selection detection methods, based on various theoretical models and exploiting different aspects of selection signatures, have been developed. Their applications at the species and population levels have respectively led to the identification of human specific selection events that distinguish human from nonhuman primates and local adaptation events that contribute to human diversity. Scrutiny of candidate genes has revealed paradigms of adaptations to specific nutritional components and genome-wide selection scans have verified the prevalence of diet-related selection events and provided many more candidates awaiting further investigation. Understanding the role of diet in human evolution is fundamental for the development of evidence-based, genome-informed nutritional practices in the era of personal genomics.

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds

PubMed Central

Poojary, Mahesha M.; Barba, Francisco J.; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A.; Juliano, Pablo

2016-01-01

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability. PMID:27879659

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds.

PubMed

Poojary, Mahesha M; Barba, Francisco J; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A; Juliano, Pablo

2016-11-22

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability.

Digital stereoscopic cinema: the 21st century

NASA Astrophysics Data System (ADS)

Lipton, Lenny

2008-02-01

Over 1000 theaters in more than a dozen countries have been outfitted with digital projectors using the Texas Instruments DLP engine equipped to show field-sequential 3-D movies using the polarized method of image selection. Shuttering eyewear and advanced anaglyph products are also being deployed for image selection. Many studios are in production with stereoscopic films, and some have committed to producing their entire output of animated features in 3-D. This is a time of technology change for the motion picture industry.

The Athena optics

NASA Astrophysics Data System (ADS)

Bavdaz, Marcos; Wille, Eric; Shortt, Brian; Fransen, Sebastiaan; Collon, Maximilien; Vacanti, Giuseppe; Günther, Ramses; Yanson, Alexei; Vervest, Mark; Haneveld, Jeroen; van Baren, Coen; Zuknik, Karl-Heinz; Christensen, Finn; Krumrey, Michael; Burwitz, Vadim; Pareschi, Giovanni; Valsecchi, Giuseppe

2015-09-01

The Advanced Telescope for High ENergy Astrophysics (Athena) was selected in 2014 as the second large class mission (L2) of the ESA Cosmic Vision Science Programme within the Directorate of Science and Robotic Exploration. The mission development is proceeding via the implementation of the system studies and in parallel a comprehensive series of technology preparation activities. [1-3]. The core enabling technology for the high performance mirror is the Silicon Pore Optics (SPO), a modular X-ray optics technology, which utilises processes and equipment developed for the semiconductor industry [4-31]. This paper provides an overview of the programmatic background, the status of SPO technology and give an outline of the development roadmap and activities undertaken and planned by ESA.

Propulsion Integrated Vehicle Health Management Technology Experiment (PITEX) Conducted

NASA Technical Reports Server (NTRS)

Maul, William A.; Chicatelli, Amy K.; Fulton, Christopher E.

2004-01-01

The Propulsion Integrated Vehicle Health Management (IVHM) Technology Experiment (PITEX) is a continuing NASA effort being conducted cooperatively by the NASA Glenn Research Center, the NASA Ames Research Center, and the NASA Kennedy Space Center. It was a key element of a Space Launch Initiative risk-reduction task performed by the Northrop Grumman Corporation in El Segundo, California. PITEX's main objectives are the continued maturation of diagnostic technologies that are relevant to second generation reusable launch vehicle (RLV) subsystems and the assessment of the real-time performance of the PITEX diagnostic solution. The PITEX effort has considerable legacy in the NASA IVHM Technology Experiment for X-vehicles (NITEX) that was selected to fly on the X-34 subscale RLV that was being developed by Orbital Sciences Corporation. NITEX, funded through the Future-X Program Office, was to advance the technology-readiness level of selected IVHM technologies within a flight environment and to begin the transition of these technologies from experimental status into RLV baseline designs. The experiment was to perform realtime fault detection and isolation and suggest potential recovery actions for the X-34 main propulsion system (MPS) during all mission phases by using a combination of system-level analysis and detailed diagnostic algorithms.

Exploratory Technology Research Program for electrochemical energy storage

NASA Astrophysics Data System (ADS)

Kinoshita, Kim

1994-09-01

The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV's). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the ETR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EV's. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

Exploratory Technology Research Program for electrochemical energy storage

NASA Astrophysics Data System (ADS)

Kinoshita, Kim

1994-09-01

The U.S. Department of Energy's Office of Propulsion Systems provides support for an Electrochemical Energy Storage Program, that includes research and development (R&D) on advanced rechargeable batteries and fuel cells. A major goal of this program is to develop electrochemical power sources suitable for application in electric vehicles (EV's). The program centers on advanced systems that offer the potential for high performance and low life-cycle costs, both of which are necessary to permit significant penetration into commercial markets. The DOE Electrochemical Energy Storage Program is divided into two projects: the Electric Vehicle Advanced Battery Systems (EVABS) Development Program and the Exploratory Technology Research (ETR) Program. The EVABS Program management responsibility has been assigned to Sandia National Laboratories (SNL); Lawrence Berkeley Laboratory (LBL) is responsible for management of the FIR Program. The EVABS and ETR Programs include an integrated matrix of R&D efforts designed to advance progress on selected candidate electrochemical systems. The United States Advanced Battery Consortium (USABC), a tripartite undertaking between DOE, the U.S. automobile manufacturers and the Electric Power Research Institute (EPRI), was formed in 1991 to accelerate the development of advanced batteries for consumer EV's. The role of the FIR Program is to perform supporting research on the advanced battery systems under development by the USABC and EVABS Program, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the ETR Program is to identify the most promising electrochemical technologies and transfer them to the USABC, the battery industry and/or the EVABS Program for further development and scale-up. This report summarizes the research, financial and management activities relevant to the ETR Program in CY 1993.

The coming revolution in personal care robotics: what does it mean for nurses?

PubMed

Sharts-Hopko, Nancy C

2014-01-01

The business sector provides regular reportage on the development of personal care robots to enable elders and people with disabilities to remain in their homes. Technology in this area is advancing rapidly in Asia, Europe, and North America. To date, the nursing literature has not addressed how nurses will assist these vulnerable populations in the selection and use of robotic technology or how robotics could effect nursing care and patient outcomes. This article provides an overview of development in the area of personal care robotics to address societal needs reflecting demographic trends. Selected relevant issues related to the human-robotic interface including ethical concerns are identified. Implications for nursing education and the delivery of nursing services are identified. Collaboration with engineers in the development of personal care robotic technology has the potential to contribute to the creation of products that optimally address the needs of elders and people with disabilities.

Laser technology developments in support of ESA's earth observation missions

NASA Astrophysics Data System (ADS)

Durand, Y.; Bézy, J.-L.; Meynart, R.

2008-02-01

Within the context of ESA's Living Planet Programme, the European Space Agency has selected three missions embarking lidar instruments: ADM-Aeolus (Atmospheric Dynamics Mission) planed for launch in 2009 with a Doppler Wind Lidar, ALADIN, as unique payload; EarthCARE (Earth Clouds, Aerosols, and Radiation Explorer) planed for launch in 2013 including an ATmospheric backscatter LIDar (ATLID); at last, A-SCOPE (Advanced Space Carbon and Climate Observation of Planet Earth), candidate for the 7 th Earth Explorer, relying on a CO II Total Column Differential Absorption Lidar. To mitigate the technical risks for selected missions associated with the different sorts of lidar, ESA has undertaken critical technology developments, from the transmitter to the receiver and covering both components and sub-systems development and characterization. The purpose of this paper is to present the latest results obtained in the area of laser technology that are currently ongoing in support to EarthCARE, A-SCOPE and ADM-Aeolus.

Psych-related iPhone apps.

PubMed

Harrison, Anthony Mark; Goozee, Rhianna

2014-02-01

iPhone apps are a widely utilised technology that have recently been identified as a useful medium for health research, clinical interventions and education. While some researchers have discussed advances in app technology, others promote specific apps that are not free to access. To our knowledge, no study has conducted a review of current, free iPhone apps related to psychology, psychiatry and mental health. Therefore, we conducted a pilot, web-based review exploring free iPhone apps using a replicable search strategy within the iTunes Store search function. A selection of apps were selected and subjectively assessed in terms of their usability, utility, graphics, and associated costs for the consumer. We concluded that the apps reviewed, though novel, are limited in their scope and utility. We also note a significant gap in more scientific, evidence-based app technology, and pose some pertinent ethical questions when developing future psych-related apps.

Recent Advances in the Fabrication and Application of Screen-Printed Electrochemical (Bio)Sensors Based on Carbon Materials for Biomedical, Agri-Food and Environmental Analyses

PubMed Central

Hughes, Gareth; Westmacott, Kelly; Honeychurch, Kevin C.; Crew, Adrian; Pemberton, Roy M.; Hart, John P.

2016-01-01

This review describes recent advances in the fabrication of electrochemical (bio)sensors based on screen-printing technology involving carbon materials and their application in biomedical, agri-food and environmental analyses. It will focus on the various strategies employed in the fabrication of screen-printed (bio)sensors, together with their performance characteristics; the application of these devices for the measurement of selected naturally occurring biomolecules, environmental pollutants and toxins will be discussed. PMID:27690118

Effect of broadened-specification fuels on aircraft engines and fuel systems

NASA Technical Reports Server (NTRS)

Rudey, R. A.

1979-01-01

A wide variety of studies on the potential effects of broadened-specification fuels on future aircraft engines and fuel systems are summarized. The compositions and characteristics of aircraft fuels that may be derived from current and future crude-oil sources are described, and the most critical properties that may effect aircraft engines and fuel systems are identified and discussed. The problems that are most likely to be encountered because of changes in selected fuel properties are explored; and the related effects on engine performance, component durability and maintenance, and aircraft fuel-system performance are examined. The ability of current technology to accept possible future fuel specification changes is assessed and selected technological advances that can reduce the severity of the potential problems are illustrated.

Effect of broadened-specification fuels on aircraft engines and fuel systems

NASA Technical Reports Server (NTRS)

Rudey, R. A.

1979-01-01

A wide variety of studies on the potential effects of broadened-specification fuels on future aircraft engines and fuel systems are summarized. The compositions and characteristics of aircraft fuels that may be derived from current and future crude-oil sources are described, and the most critical properties that may affect aircraft engines and fuel systems are identified and discussed. The problems that are most likely to be encountered because of changes in selected fuel properties are described; and the related effects on engine performance, component durability and maintenance, and aircraft fuel-system performance are discussed. The ability of current technology to accept possible future fuel-specification changes is discussed, and selected technological advances that can reduce the severity of the potential problems are illustrated.

Single stage, low noise, advanced technology fan. Volume 5: Fan acoustics. Section 2: One-third octave data tabulations and selected narrowband traces

NASA Technical Reports Server (NTRS)

Jutras, R. R.

1976-01-01

The raw-acoustic data corrected to standard day, from acoustic tests performed on a 0.508-scale fan vehicle of a 111,300 newton thrust, full-size engine, which has application on an advanced transport aircraft, are presented. The single-stage advanced technology fan was designed to a pressure ratio of 1.8 at a tip speed of 503 m/sec to achieve the desired pressure ratio in a single-stage fan with low radius ratio, and to maintain adequate stall margin. The two basic approaches taken in the acoustic design were: (1) minimization of noise at the source, and (2) suppression of the generated noise in the inlet and bypass exhaust duct. Suppression of the generated noise was accomplished in the inlet through use of the hybrid concept (wall acoustic treatment plus airflow acceleration suppression) and in the exhaust duct with extensive acoustic treatment including a splitter. The goal of the design was attainment of twenty effective perceived noise decibels. The suppression goal of FAR 36-20 was not reached, but improvements in the technology of both front and aft fan-noise suppression were realized.

Advanced plasma etch technologies for nanopatterning

NASA Astrophysics Data System (ADS)

Wise, Rich

2013-10-01

Advances in patterning techniques have enabled the extension of immersion lithography from 65/45 nm through 14/10 nm device technologies. A key to this increase in patterning capability has been innovation in the subsequent dry plasma etch processing steps. Multiple exposure techniques, such as litho-etch-litho-etch, sidewall image transfer, line/cut mask, and self-aligned structures, have been implemented to solution required device scaling. Advances in dry plasma etch process control across wafer uniformity and etch selectivity to both masking materials have enabled adoption of vertical devices and thin film scaling for increased device performance at a given pitch. Plasma etch processes, such as trilayer etches, aggressive critical dimension shrink techniques, and the extension of resist trim processes, have increased the attainable device dimensions at a given imaging capability. Precise control of the plasma etch parameters affecting across-design variation, defectivity, profile stability within wafer, within lot, and across tools has been successfully implemented to provide manufacturable patterning technology solutions. IBM has addressed these patterning challenges through an integrated total patterning solutions team to provide seamless and synergistic patterning processes to device and integration internal customers. We will discuss these challenges and the innovative plasma etch solutions pioneered by IBM and our alliance partners.

Advanced plasma etch technologies for nanopatterning

NASA Astrophysics Data System (ADS)

Wise, Rich

2012-03-01

Advances in patterning techniques have enabled the extension of immersion lithography from 65/45nm through 14/10nm device technologies. A key to this increase in patterning capability has been innovation in the subsequent dry plasma etch processing steps. Multiple exposure techniques such as litho-etch-litho-etch, sidewall image transfer, line/cut mask and self-aligned structures have been implemented to solution required device scaling. Advances in dry plasma etch process control, across wafer uniformity and etch selectivity to both masking materials and have enabled adoption of vertical devices and thin film scaling for increased device performance at a given pitch. Plasma etch processes such as trilayer etches, aggressive CD shrink techniques, and the extension of resist trim processes have increased the attainable device dimensions at a given imaging capability. Precise control of the plasma etch parameters affecting across design variation, defectivity, profile stability within wafer, within lot, and across tools have been successfully implemented to provide manufacturable patterning technology solutions. IBM has addressed these patterning challenges through an integrated Total Patterning Solutions team to provide seamless and synergistic patterning processes to device and integration internal customers. This paper will discuss these challenges and the innovative plasma etch solutions pioneered by IBM and our alliance partners.

Building the future an atom at a time: Realizing feynman's vision

NASA Astrophysics Data System (ADS)

Madia, William J.

2006-10-01

Since Feynman’s 1959 lecture, “There’s Plenty of Room at the Bottom,” and particularly in the last 15 years, advances in instrumentation have permitted us to observe and characterize materials at atomic scale. New and even more powerful capabilities are rapidly becoming available. At the same time, our theoretical understanding and ability to model complex systems have matured to a level that enables us to begin making useful predictions in many areas, with the promise of further progress as we approach petascale computing. Progress in making and structuring nanoscale materials in commercially useful quantities is also being made, albeit more selectively. Exploiting chemistry and biochemistry to mimic nature’s accomplishments in living systems is a promising approach that is opening new possibilities. The remarkable progress of the last few years is already producing technological advances, and more can be expected as investments in nanoscience and nanotechnology increase. Just as advances in information technology during the second half of the 20th century produced dramatic technological, economic, and societal changes, so the coming nanoscale revolution will affect virtually every aspect of life in the 21st century.

Building the future an atom at a time: Realizing Feynman's vision

NASA Astrophysics Data System (ADS)

Madia, William J.

2006-10-01

Since Feynman’s 1959 lecture, “There’s Plenty of Room at the Bottom,” and particularly in the last 15 years, advances in instrumentation have permitted us to observe and characterize materials at atomic scale. New and even more powerful capabilities are rapidly becoming available. At the same time, our theoretical understanding and ability to model complex systems have matured to a level that enables us to begin making useful predictions in many areas, with the promise of further progress as we approach petascale computing. Progress in making and structuring nanoscale materials in commercially useful quantities is also being made, albeit more selectively. Exploiting chemistry and biochemistry to mimic nature’s accomplishments in living systems is a promising approach that is opening new possibilities. The remarkable progress of the last few years is already producing technological advances, and more can be expected as investments in nanoscience and nanotechnology increase. Just as advances in information technology during the second half of the 20th century produced dramatic technological, economic, and societal changes, so the coming nanoscale revolution will affect virtually every aspect of life in the 21st century.

Energy Efficient Engine (E3) combustion system component technology performance report

NASA Technical Reports Server (NTRS)

Burrus, D. L.; Chahrour, C. A.; Foltz, H. L.; Sabla, P. E.; Seto, S. P.; Taylor, J. R.

1984-01-01

The Energy Efficient Engine (E3) combustor effort was conducted as part of the overall NASA/GE E3 Program. This effort included the selection of an advanced double-annular combustion system design. The primary intent of this effort was to evolve a design that meets the stringent emissions and life goals of the E3, as well as all of the usual performance requirements of combustion systems for modern turbofan engines. Numerous detailed design studies were conducted to define the features of the combustion system design. Development test hardware was fabricated, and an extensive testing effort was undertaken to evaluate the combustion system subcomponents in order to verify and refine the design. Technology derived from this effort was incorporated into the engine combustion hardware design. The advanced engine combustion system was then evaluated in component testing to verify the design intent. What evolved from this effort was an advanced combustion system capable of satisfying all of the combustion system design objectives and requirements of the E3.

Targeted Structural Optimization with Additive Manufacturing of Metals

NASA Technical Reports Server (NTRS)

Burt, Adam; Hull, Patrick

2015-01-01

The recent advances in additive manufacturing (AM) of metals have now improved the state-of-the-art such that traditionally non-producible parts can be readily produced in a cost-effective way. Because of these advances in manufacturing technology, structural optimization techniques are well positioned to supplement and advance this new technology. The goal of this project is to develop a structural design, analysis, and optimization framework combined with AM to significantly light-weight the interior of metallic structures while maintaining the selected structural properties of the original solid. This is a new state-of-the-art capability to significantly reduce mass, while maintaining the structural integrity of the original design, something that can only be done with AM. In addition, this framework will couple the design, analysis, and fabrication process, meaning that what has been designed directly represents the produced part, thus closing the loop on the design cycle and removing human iteration between design and fabrication. This fundamental concept has applications from light-weighting launch vehicle components to in situ resource fabrication.

Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory

NASA Technical Reports Server (NTRS)

Uhran, M. L.; Youngblood, W. W.; Georgekutty, T.; Fiske, M. R.; Wear, W. O.

1986-01-01

Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved materials having applications across the commercial spectrum. Previous studies have been performed to define from the researcher's perspective, the requirements for laboratory equipment to accommodate microgravity experiments on the space station. Functional requirements for the identified experimental apparatus and support equipment were determined. From these hardware requirements, several items were selected for concept designs and subsequent formulation of development plans. This report documents the concept designs and development plans for two items of experiment apparatus - the Combustion Tunnel and the Advanced Modular Furnace, and two items of support equipment the Laser Diagnostic System and the Integrated Electronics Laboratory. For each concept design, key technology developments were identified that are required to enable or enhance the development of the respective hardware.

Gametic embryogenesis and haploid technology as valuable support to plant breeding.

PubMed

Germanà, Maria Antonietta

2011-05-01

Plant breeding is focused on continuously increasing crop production to meet the needs of an ever-growing world population, improving food quality to ensure a long and healthy life and address the problems of global warming and environment pollution, together with the challenges of developing novel sources of biofuels. The breeders' search for novel genetic combinations, with which to select plants with improved traits to satisfy both farmers and consumers, is endless. About half of the dramatic increase in crop yield obtained in the second half of the last century has been achieved thanks to the results of genetic improvement, while the residual advance has been due to the enhanced management techniques (pest and disease control, fertilization, and irrigation). Biotechnologies provide powerful tools for plant breeding, and among these ones, tissue culture, particularly haploid and doubled haploid technology, can effectively help to select superior plants. In fact, haploids (Hs), which are plants with gametophytic chromosome number, and doubled haploids (DHs), which are haploids that have undergone chromosome duplication, represent a particularly attractive biotechnological method to accelerate plant breeding. Currently, haploid technology, making possible through gametic embryogenesis the single-step development of complete homozygous lines from heterozygous parents, has already had a huge impact on agricultural systems of many agronomically important crops, representing an integral part in their improvement programmes. The aim of this review was to provide some background, recent advances, and future prospective on the employment of haploid technology through gametic embryogenesis as a powerful tool to support plant breeding.

Fusion technologies for Laser Inertial Fusion Energy (LIFE)

NASA Astrophysics Data System (ADS)

Kramer, K. J.; Latkowski, J. F.; Abbott, R. P.; Anklam, T. P.; Dunne, A. M.; El-Dasher, B. S.; Flowers, D. L.; Fluss, M. J.; Lafuente, A.; Loosmore, G. A.; Morris, K. R.; Moses, E.; Reyes, S.

2013-11-01

The Laser Inertial Fusion-based Energy (LIFE) engine design builds upon on going progress at the National Ignition Facility (NIF) and offers a near-term pathway to commercial fusion. Fusion technologies that are critical to success are reflected in the design of the first wall, blanket and tritium separation subsystems. The present work describes the LIFE engine-related components and technologies. LIFE utilizes a thermally robust indirect-drive target and a chamber fill gas. Coolant selection and a large chamber solid-angle coverage provide ample tritium breeding margin and high blanket gain. Target material selection eliminates the need for aggressive chamber clearing, while enabling recycling. Demonstrated tritium separation and storage technologies limit the site tritium inventory to attractive levels. These key technologies, along with the maintenance and advanced materials qualification program have been integrated into the LIFE delivery plan. This describes the development of components and subsystems, through prototyping and integration into a First Of A Kind power plant. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

A Study of the Utilization of Advanced Composites in Fuselage Structures of Commercial Aircraft

NASA Technical Reports Server (NTRS)

Watts, D. J.; Sumida, P. T.; Bunin, B. L.; Janicki, G. S.; Walker, J. V.; Fox, B. R.

1985-01-01

A study was conducted to define the technology and data needed to support the introduction of advanced composites in the future production of fuselage structure in large transport aircraft. Fuselage structures of six candidate airplanes were evaluated for the baseline component. The MD-100 was selected on the basis of its representation of 1990s fuselage structure, an available data base, its impact on the schedule and cost of the development program, and its availability and suitability for flight service evaluation. Acceptance criteria were defined, technology issues were identified, and a composite fuselage technology development plan, including full-scale tests, was identified. The plan was based on composite materials to be available in the mid to late 1980s. Program resources required to develop composite fuselage technology are estimated at a rough order of magnitude to be 877 man-years exclusive of the bird strike and impact dynamic test components. A conceptual composite fuselage was designed, retaining the basic MD-100 structural arrangement for doors, windows, wing, wheel wells, cockpit enclosure, major bulkheads, etc., resulting in a 32 percent weight savings.

2007 Research and Technology

NASA Technical Reports Server (NTRS)

Riddlebaugh, Stephen M. (Editor)

2008-01-01

The NASA Glenn Research Center is pushing the envelope of research and technology in aeronautics, space exploration, science, and space operations. Our research in aeropropulsion, structures and materials, and instrumentation and controls is enabling next-generation transportation systems that are faster, more environmentally friendly, more fuel efficient, and safer. Our research and development of space flight systems is enabling advanced power, propulsion, communications, and human health systems that will advance the exploration of our solar system. This report selectively summarizes NASA Glenn Research Center s research and technology accomplishments for fiscal year 2007. Comprising 104 short articles submitted by the staff scientists and engineers, the report is organized into six major sections: Aeropropulsion, Power and Space Propulsion, Communications, Space Processes and Experiments, Instrumentation and Controls, and Structures and Materials. It is not intended to be a comprehensive summary of all the research and technology work done over the past fiscal year; most of the work is reported in Glenn-published technical reports, journal articles, and presentations. For each article in this report, a Glenn contact person has been identified, and where possible, a reference document is listed so that additional information can be easily obtained.

High temperature, harsh environment sensors for advanced power generation systems

NASA Astrophysics Data System (ADS)

Ohodnicki, P. R.; Credle, S.; Buric, M.; Lewis, R.; Seachman, S.

2015-05-01

One mission of the Crosscutting Technology Research program at the National Energy Technology Laboratory is to develop a suite of sensors and controls technologies that will ultimately increase efficiencies of existing fossil-fuel fired power plants and enable a new generation of more efficient and lower emission power generation technologies. The program seeks to accomplish this mission through soliciting, managing, and monitoring a broad range of projects both internal and external to the laboratory which span sensor material and device development, energy harvesting and wireless telemetry methodologies, and advanced controls algorithms and approaches. A particular emphasis is placed upon harsh environment sensing for compatibility with high temperature, erosive, corrosive, and highly reducing or oxidizing environments associated with large-scale centralized power generation. An overview of the full sensors and controls portfolio is presented and a selected set of current and recent research successes and on-going projects are highlighted. A more detailed emphasis will be placed on an overview of the current research thrusts and successes of the in-house sensor material and device research efforts that have been established to support the program.

App Factory: A flexible approach to rehabilitation engineering in an era of rapid technology advancement.

PubMed

Jones, Michael; Mueller, James; Morris, John

2017-01-01

This article describes a flexible and effective approach to research and development in an era of rapid technological advancement. The approach relies on secondary dispersal of grant funds to commercial developers through a competitive selection process. This "App Factory" model balances the practical reliance on multi-year funding needed to sustain a rehabilitation engineering research center (RERC), with the need for agility and adaptability of development efforts undertaken in a rapidly changing technology environment. This approach also allows us to take advantage of technical expertise needed to accomplish a particular development task, and provides incentives to deliver successful products in a cost-effective manner. In this article, we describe the App Factory structure, process, and results achieved to date; and we discuss the lessons learned and the potential relevance of this approach for other grant-funded research and development efforts. Data presented on the direct costs and number of downloads of the 16 app development projects funded in the App Factory's first 3 years show that it can be an effective means for supporting focused, short-term assistive technology development projects.

Technology Solutions Case Study: Stud Walls with Continuous Exterior Insulation for Factory Built Housing

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research — stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Assessment of research needs for laser technologies applied to advanced spectroscopic methods

NASA Astrophysics Data System (ADS)

1990-01-01

The Department of Energy (DOE) recognizes that new developments in laser technology and laser spectroscopy can substantially improve the ability to carry out the mission of its Office of Health and Environmental Research (OHER). In brief, the mission of OHER is to support programs of research which allow DOE to understand and anticipate long term effects upon human health and the environment from the production and utilization of alternate forms of energy, and to apply the department's unique capabilities to solve numerous problems in biology and medicine. A DOE study was managed by Consultec Scientific, Inc. who furnished from its staff the Principal Investigator who, in turn, coordinated the enthusiastic efforts of a group of consultants consisting of some of the world's best scientists. The panel made six specific recommendations which dealt with three important areas. First the panel recommends that OHER closely monitor and be prepared to use the advances now being made in solid-state laser technology. These advances, comparable in nature to the revolution which began during the 1950's in solid-state electronics, will radically improve present-day laser technology. Secondly, the panel addressed the use of this advanced technology to maintain the preeminent position which OHER has already created for itself in the development of selective and sensitive instruments for the analysis of atomic and molecular substances and to extend the use of these to measure chemical pollutants in air, soil, and water. Finally, another area of the recommendations dealt with the use of lasers to determine structural and dynamical features of macromolecules and especially to develop x ray lasers and other imaging techniques, including holographic ones, for sequencing DNA and the human genome.

Phosphorus removal from Everglades agricultural area runoff by submerged aquatic vegetation/limerock treatment technology: an overview of research.

PubMed

Gu, B; DeBusk, T A; Dierberg, F E; Chimney, M J; Pietro, K C; Aziz, T

2001-01-01

The 1994 Everglades Forever Act mandates the South Florida Water Management District and the Florida Department of Environmental Protection to evaluate a series of advanced treatment technologies to reduce total phosphorus (TP) in Everglades Agricultural Area runoff to a threshold target level. A submerged aquatic vegetation/limerock (SAV/LR) treatment system is one of the technologies selected for evaluation. The research program consists of two phases. Phase I examined the efficiency of SAV/LR treatment system for TP removal at the mesocosm scale. Preliminary results demonstrate that this technology is capable of reducing effluent TP to as low as 10 microg/L under constant flows. The SAV component removes the majority of the influent soluble reactive P, while the limerock component removes a portion of the particulate P. Phase II is a multi-scale project (i.e., microcosms, mesocosms, test cells and full-size wetlands). Experiments and field investigations using various environmental scenarios are designed to (1) identify key P removal processes; (2) provide management and operational criteria for basin-scale implementation; and (3) provide scientific data for a standardized comparison of performance among advanced treatment technologies.

Materials for advanced rocket engine turbopump turbine blades

NASA Technical Reports Server (NTRS)

Chandler, W. T.

1985-01-01

A study program was conducted to identify those materials that will provide the greatest benefits as turbine blades for advanced liquid propellant rocket engine turbines and to prepare technology plans for the development of those materials for use in the 1990 through 1995 period. The candidate materials were selected from six classes of materials: single-crystal (SC) superalloys, oxide dispersion-strengthened (ODS) superalloys, rapid solidification processed (RSP) superalloys, directionally solidified eutectic (DSE) superalloys, fiber-reinforced superalloy (FRS) composites, and ceramics. Properties of materials from the six classes were compiled and evaluated and property improvements were projected approximately 5 years into the future for advanced versions of materials in each of the six classes.

Advances in Mid-Infrared Spectroscopy for Chemical Analysis

NASA Astrophysics Data System (ADS)

Haas, Julian; Mizaikoff, Boris

2016-06-01

Infrared spectroscopy in the 3-20 μm spectral window has evolved from a routine laboratory technique into a state-of-the-art spectroscopy and sensing tool by benefitting from recent progress in increasingly sophisticated spectra acquisition techniques and advanced materials for generating, guiding, and detecting mid-infrared (MIR) radiation. Today, MIR spectroscopy provides molecular information with trace to ultratrace sensitivity, fast data acquisition rates, and high spectral resolution catering to demanding applications in bioanalytics, for example, and to improved routine analysis. In addition to advances in miniaturized device technology without sacrificing analytical performance, selected innovative applications for MIR spectroscopy ranging from process analysis to biotechnology and medical diagnostics are highlighted in this review.

Technical and economic assessment of processes for the production of butanol and acetone. Phase two: analysis of research advances. Energy Conversion and Utilization Technologies Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1984-08-01

The initial objective of this work was to develop a methodology for analyzing the impact of technological advances as a tool to help establish priorities for R and D options in the field of biocatalysis. As an example of a biocatalyzed process, butanol/acetone fermentation (ABE process) was selected as the specific topic of study. A base case model characterizing the technology and economics associated with the ABE process was developed in the previous first phase of study. The project objectives were broadened in this second phase of work to provide parametric estimates of the economic and energy impacts of amore » variety of research advances in the hydrolysis, fermentation and purification sections of the process. The research advances analyzed in this study were based on a comprehensive literature review. The six process options analyzed were: continuous ABE fermentaton; vacuum ABE fermentation; Baelene solvent extraction; HRI's Lignol process; improved prehydrolysis/dual enzyme hydrolysis; and improved microorganism tolerance to butanol toxicity. Of the six options analyzed, only improved microorganism tolerance to butanol toxicity had a significant positive effect on energy efficiency and economics. This particular process option reduced the base case production cost (including 10% DCF return) by 20% and energy consumption by 16%. Figures and tables.« less

Communicating the Future: Best Practices for Communication of Science and Technology to the Public

DOE Office of Scientific and Technical Information (OSTI.GOV)

Porter, Gail

To advance the state of the art in science and technology communication to the public a conference was held March 6-8, 2002 at the National Institute of Standards and Technology in Gaithersburg, MD. This report of the conference proceedings includes a summary statement by the conference steering committee, transcripts or other text summarizing the remarks of conference speakers, and abstracts for 48 "best practice" communications programs selected by the steering committee through an open competition and a formal peer review process. Additional information about the 48 best practice programs is available on the archival conference Web site at www.nist.gov/bestpractices.

Selecting Advanced Software Technology in Two Small Manufacturing Enterprises

DTIC Science & Technology

2004-05-01

improving workflow to further reduce delivery times, enhance customer service, and obtain a competitive advantage . The company wanted help... environment , stakeholders’ needs, ecommerce , shop floor visualization, and collaboration capability. These statements are not significantly different...for the purpose of describing a software environment . This identification does not imply any recommendation or endorsement by NIST, the SEI, CMU, or

Trends Impacting One Public School Program for Students Who Are Deaf or Hard-of-Hearing

ERIC Educational Resources Information Center

Miller, Kevin J.

2014-01-01

This article reflects on the author's experience supervising a public school program for students who are deaf or hard-of-hearing, specifically addressing national, regional, and local trends affecting it. These trends included teacher efficacy, changes in educational service delivery, advances in technology, the selection of the listening and…

How Can We Use Corpus Wordlists for Language Learning? Interfaces between Computer Corpora and Expert Intervention

ERIC Educational Resources Information Center

Chen, Yu-Hua; Bruncak, Radovan

2015-01-01

With the advances in technology, wordlists retrieved from computer corpora have become increasingly popular in recent years. The lexical items in those wordlists are usually selected, according to a set of robust frequency and dispersion criteria, from large corpora of authentic and naturally occurring language. Corpus wordlists are of great value…

Modeling large-scale winter recreation terrain selection with implications for recreation management and wildlife

Treesearch

Lucretia E. Olson; John R. Squires; Elizabeth K. Roberts; Aubrey D. Miller; Jacob S. Ivan; Mark Hebblewhite

2017-01-01

Winter recreation is a rapidly growing activity, and advances in technology make it possible for increasing numbers of people to access remote backcountry terrain. Increased winter recreation may lead to more frequent conflict between recreationists, as well as greater potential disturbance to wildlife. To better understand the environmental characteristics favored by...

E-Books in Academic Libraries: Challenges for Acquisition and Collection Management

ERIC Educational Resources Information Center

Walters, William H.

2013-01-01

This bibliographic essay examines the difficulties associated with the selection, licensing, acquisition, and management of e-books in academic libraries. The potential advantages of e-book technology are likely to be realized only to the extent that they advance the economic goals of e-book suppliers and are consistent with the legal framework…

Application of Polarimetric-Interferometric Phase Coherence Optimization (PIPCO) Procedure to SIR-C/X-SAR Tien-Shan Tracks 122.20(94 Oct. 08)/154.20(94 Oct. 09) Repeat-Orbit C/L-Band Pol-D-InSAR Imag

NASA Technical Reports Server (NTRS)

Boerner, W. M.; Mott, H.; Verdi, J.; Darizhapov, D.; Dorjiev, B.; Tsybjito, T.; Korsunov, V.; Tatchkov, G.; Bashkuyev, Y.; Cloude, S.;

Selected Papers from the National Conference on College Teaching and Learning (5th, Jacksonville, Florida, April 6-9, 1994).

ERIC Educational Resources Information Center

Chambers, Jack A., Ed.

This collection of 18 papers covers four broad areas of teaching and learning in higher education: innovative college teaching/learning strategies; effective classroom research/assessment activities; advanced classroom technology; and developing teaching and learning centers. Papers also address the question of how the college classroom is…

The Use of Software in Academic Stream High School Mathematics Teaching

ERIC Educational Resources Information Center

Clay, Simon; Fotou, Nikolaos; Monaghan, John

2017-01-01

This paper reports on classroom observations of senior high school mathematics lessons with a focus on the use of digital technology. The observations were of teachers enrolled in an in-service course, Teaching Advanced Mathematics. The paper reports selected results and comments on: software that was observed to have been used; the use (or not)…

Construction and Analysis of Educational Tests Using Abductive Machine Learning

ERIC Educational Resources Information Center

El-Alfy, El-Sayed M.; Abdel-Aal, Radwan E.

2008-01-01

Recent advances in educational technologies and the wide-spread use of computers in schools have fueled innovations in test construction and analysis. As the measurement accuracy of a test depends on the quality of the items it includes, item selection procedures play a central role in this process. Mathematical programming and the item response…

Induced mutation and epigenetics modification in plants for crop improvement by targeting CRISPR/Cas9 technology.

PubMed

Khan, Muhammad Hafeez Ullah; Khan, Shahid U; Muhammad, Ali; Hu, Limin; Yang, Yang; Fan, Chuchuan

2018-06-01

Clustered regularly interspaced palindromic repeats associated protein Cas9 (CRISPR-Cas9), originally an adaptive immunity system of prokaryotes, is revolutionizing genome editing technologies with minimal off-targets in the present era. The CRISPR/Cas9 is now highly emergent, advanced, and highly specific tool for genome engineering. The technology is widely used to animal and plant genomes to achieve desirable results. The present review will encompass how CRISPR-Cas9 is revealing its beneficial role in characterizing plant genetic functions, genomic rearrangement, how it advances the site-specific mutagenesis, and epigenetics modification in plants to improve the yield of field crops with minimal side-effects. The possible pitfalls of using and designing CRISPR-Cas9 for plant genome editing are also discussed for its more appropriate applications in plant biology. Therefore, CRISPR/Cas9 system has multiple benefits that mostly scientists select for genome editing in several biological systems. © 2017 Wiley Periodicals, Inc.

Technology advances needed for photovoltaics to achieve widespread grid price parity: Widespread grid price parity for photovoltaics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones-Albertus, Rebecca; Feldman, David; Fu, Ran

2016-04-20

To quantify the potential value of technological advances to the photovoltaics (PV) sector, this paper examines the impact of changes to key PV module and system parameters on the levelized cost of energy (LCOE). The parameters selected include module manufacturing cost, efficiency, degradation rate, and service lifetime. NREL's System Advisor Model (SAM) is used to calculate the lifecycle cost per kilowatt-hour (kWh) for residential, commercial, and utility scale PV systems within the contiguous United States, with a focus on utility scale. Different technological pathways are illustrated that may achieve the Department of Energy's SunShot goal of PV electricity that ismore » at grid price parity with conventional electricity sources. In addition, the impacts on the 2015 baseline LCOE due to changes to each parameter are shown. These results may be used to identify research directions with the greatest potential to impact the cost of PV electricity.« less

Progress and Challenges in Macroencapsulation Approaches for Type 1 Diabetes (T1D) Treatment: Cells, Biomaterials, and Devices

PubMed Central

Song, Shang; Roy, Shuvo

2018-01-01

Macroencapsulation technology has been an attractive topic in the field of treatment for Type 1 diabetes due to mechanical stability, versatility, and retrievability of the macrocapsule design. Macro-capsules can be categorized into extravascular and intravascular devices, in which solute transport relies either on diffusion or convection, respectively. Failure of macroencapsulation strategies can be due to limited regenerative capacity of the encased insulin-producing cells, sub-optimal performance of encapsulation biomaterials, insufficient immunoisolation, excessive blood thrombosis for vascular perfusion devices, and inadequate modes of mass transfer to support cell viability and function. However, significant technical advancements have been achieved in macroencapsulation technology, namely reducing diffusion distance for oxygen and nutrients, using pro-angiogenic factors to increase vascularization for islet engraftment, and optimizing membrane permeability and selectivity to prevent immune attacks from host’s body. This review presents an overview of existing macroencapsulation devices and discusses the advances based on tissue-engineering approaches that will stimulate future research and development of macroencapsulation technology. PMID:26615050

Developing a Free-Piston Stirling Convertor for advanced radioisotope space power systems

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Augenblick, John E.; White, Maurice A.; Peterson, Allen A.; Redinger, Darin L.; Petersen, Stephen L.

2002-01-01

The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. This paper provides a description of the Flight Prototype (FP) Stirling convertor design as compared to the previous TDC design. The initial flight prototype units are already undergoing performance tuning at STC. The new design will be hermetically scaled and will provide a weight reduction from approximately 4.8 kg to approximately 3.9 kg. .

Teaching of anatomical sciences: A blended learning approach.

PubMed

Khalil, Mohammed K; Abdel Meguid, Eiman M; Elkhider, Ihsan A

2018-04-01

Blended learning is the integration of different learning approaches, new technologies, and activities that combine traditional face-to-face teaching methods with authentic online methodologies. Although advances in educational technology have helped to expand the selection of different pedagogies, the teaching of anatomical sciences has been challenged by implementation difficulties and other limitations. These challenges are reported to include lack of time, costs, and lack of qualified teachers. Easy access to online information and advances in technology make it possible to resolve these limitations by adopting blended learning approaches. Blended learning strategies have been shown to improve students' academic performance, motivation, attitude, and satisfaction, and to provide convenient and flexible learning. Implementation of blended learning strategies has also proved cost effective. This article provides a theoretical foundation for blended learning and proposes a validated framework for the design of blended learning activities in the teaching and learning of anatomical sciences. Clin. Anat. 31:323-329, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

ARMD Strategic Thrust 6: Assured Autonomy for Aviation Transformation

NASA Technical Reports Server (NTRS)

Ballin, Mark; Holbrook, Jon; Sharma, Shivanjli

2016-01-01

In collaboration with the external community and other government agencies, NASA will develop enabling technologies, standards, and design guidelines to support cost-effective applications of automation and limited autonomy for individual components of aviation systems. NASA will also provide foundational knowledge and methods to support the next epoch. Research will address issues of verification and validation, operational evaluation, national policy, and societal cost-benefit. Two research and development approaches to aviation autonomy will advance in parallel. The Increasing Autonomy (IA) approach will seek to advance knowledge and technology through incremental increases in machine-based support of existing human-centered tasks, leading to long-term reallocation of functions between humans and machines. The Autonomy as a New Technology (ANT) approach seeks advances by developing technology to achieve goals that are not currently possible using human-centered concepts of operation. IA applications are mission-enhancing, and their selection will be based on benefits achievable relative to existing operations. ANT applications are mission-enabling, and their value will be assessed based on societal benefit resulting from a new capability. The expected demand for small autonomous unmanned aircraft systems (UAS) provides an opportunity for development of ANT applications. Supervisory autonomy may be implemented as an expansion of the number of functions or systems that may be controlled by an individual human operator. Convergent technology approaches, such as the use of electronic flight bags and existing network servers, will be leveraged to the maximum extent possible.

When technology, science and culture meet: insights from ancient Chinese technology

NASA Astrophysics Data System (ADS)

Lee, Yeung Chung

2017-10-01

This paper draws together two important agendas in science education. The first is making science education more inclusive such that students from non-Western or indigenous cultures can benefit from culturally relevant curricula. The second is integrating technology into the curriculum under the umbrella of Science-Technology-Society (STS) education to embrace the social aspects of science, with technology serving as a bridge. The advancement of the first agenda is hindered by the pursuance by both Western and non-Western societies of narrow cultural and practical goals without considering the development of science and technology from a cross-cultural perspective. The second agenda is limited by the misconception that technology is applied science, leading to the exclusion from STS discussions of pre-science or indigenous technologies developed by non-Western cultures. Through selected case studies of the evolution of Chinese traditional technologies and their interaction with science, this paper offers a perspective from the Far East, and argues for situating culturally responsive science education in broader historical and cross-cultural contexts to acknowledge the multi-cultural contributions to science and technology. A form of cross-cultural STS education is advanced, encompassing the cultural basis of technological developments, technology diffusion, interactions of traditional technology with science, and the potential development of traditional or indigenous technologies. This approach provides a bridge between the existing universal science education paradigm promoted in the West and the different forms of multi-cultural education advocated by indigenous science educators. To translate theory into practice, a conceptual framework is proposed in which the essential transdisciplinary knowledge base, curricular goals, and pedagogical approaches are embedded.

ETX-I: First-generation single-shaft electric propulsion system program. Volume 2: Battery

NASA Astrophysics Data System (ADS)

1988-06-01

The overall objective of this research and development program was to advance ac powertrain technology for electric vehicles (EV). The program focused on the design, build, test, and refinement of an experimental advanced electric vehicle powertrain suitable for packaging in a Ford Escort or equivalent-size vehicle. A Mercury LN7 was subsequently selected for the test bed vehicle. Although not part of the initial contract, the scope of the ETX-I Program was expanded in 1983 to encompass the development of advanced electric vehicle batteries compatible with the ETX-I powertrain and vehicle test bed. The intent of the battery portion of the ETX-I Program was to apply the best available battery technology based on existing battery developments. The battery effort was expected to result in a practical scale-up of base battery technologies to the vehicle battery subsystem level. With the addition of the battery activity, the ETX-I Program became a complete proof-of-concept ac propulsion system technology development program. In this context, the term propulsion system is defined as all components and subsystems (from the driver input to the vehicle wheels) that are required to store energy on board the vehicle and, using that energy, to provide controlled motive power to the vehicle. This report, Volume 2, describes the battery portion of the ETX-I Program. The powertrain effort is reported in Volume 1.

Two-stage, low noise advanced technology fan. 5: Acoustic final report

NASA Technical Reports Server (NTRS)

Sofrin, T. G.; Riloff, N., Jr.

1975-01-01

The NASA Q2S(quiet two-stage) fan is a 0.836m (32.9 in.) diameter model of the STF 433 engine fan, selected in a 1972 study for an Advanced Technology Transport (ATT) airplane. Noise-control features include: low tip speed, moderate stage pressure rise, large blade-vane spacings, no inlet guide vanes, and optimum blade and vane numbers. Tests were run on the baseline Q2S fan with standard inlet and discharge ducts. Further tests were made of a translating centerbody sonic inlet device and treated discharge ducts. Results were scaled to JT8D and JT3D engine fan size for comparison with current two-stage fans, and were also scaled to STF 433 fan size to compare calculated ATT flyover noise with FAR 36 limits. Baseline Q2S results scaled to JT8D and JT3D engine fan sizes showed substantial noise reductions. Calculated unsuppressed baseline ATT flyovers averaged about 2.5 EPNdB below FAR 36 limits. Using measured sonic inlet results, scaled baseline Q2S fan results, and calculated attenuations for a 1975 technology duct liner, projected flyover noise calculations for the ATT averaged about FAR 36 limits minus 10 EPNdB. Advances in suppression technology required to meet the 1985 goal of FAR 36 limits minus 20 EPNdB are discussed.

ISS ECLSS Technology Evolution for Exploration

NASA Technical Reports Server (NTRS)

Carrasquillo, Robyn L.

2005-01-01

The baseline environmental control and life support systems (ECLSS) currently deployed on the International Space Station (ISS) and the regenerative oxygen generation and water reclamation systems to be added in 2008 are based on technologies selected during the early 1990's. While they are generally meeting, or exceeding requirements for supporting the ISS crew, lessons learned from hardware development and on orbit experience, together with advances in technology state of the art, and the unique requirements for future manned exploration missions prompt consideration of the next steps to be taken to evolve these technologies to improve robustness and reliability, enhance performance, and reduce resource requirements such as power and logistics upmass. This paper discusses the current state of ISS ECLSS technology and identifies possible areas for evolutionary enhancement or improvement.

Fiber optic control system integration

NASA Technical Reports Server (NTRS)

Poppel, G. L.; Glasheen, W. M.; Russell, J. C.

1987-01-01

A total fiber optic, integrated propulsion/flight control system concept for advanced fighter aircraft is presented. Fiber optic technology pertaining to this system is identified and evaluated for application readiness. A fiber optic sensor vendor survey was completed, and the results are reported. The advantages of centralized/direct architecture are reviewed, and the concept of the protocol branch is explained. Preliminary protocol branch selections are made based on the F-18/F404 application. Concepts for new optical tools are described. Development plans for the optical technology and the described system are included.

Technical Transformation of Biodefense Vaccines

PubMed Central

Lu, Shan; Wang, Shixia

2013-01-01

Biodefense vaccines are developed against a diverse group of pathogens. Vaccines were developed for some of these pathogens a long time ago but they are facing new challenges to move beyond the old manufacturing technologies. New vaccines to be developed against other pathogens have to determine whether to follow traditional vaccination strategies or to seek new approaches. Advances in basic immunology and recombinant DNA technology have fundamentally transformed the process of formulating a vaccine concept, optimizing protective antigens, and selecting the most effective vaccine delivery approach for candidate biodefense vaccines. PMID:19837293

BRITE/EURAM: Third Technological Days for the Basic Research in Industrial Technologies in Europe/European Research in Advanced Materials 1990, Held in Brussels, Belgium on May 21-22, 1990

DTIC Science & Technology

1990-06-29

characterized by a end, and a risk assessment. multifaceted midsurface of varying thickness. Briefly, the ideal BRITE/EURAM project solves a A specific...sists of selecting, at the outset, a well-behaved mesh strengthens all participants, yet preserves their identity. covering the whole midsurface . During...developing sion in the gar direction, heat advection in the midsurface software for the manufacturing industry. The company is dirccltin, and viscous

Advances in refrigeration and heat transfer engineering

DOE PAGES

Bansal, Pradeep; Cremaschi, Prof. Lorenzo

2015-05-13

This special edition of Science and Technology for the Built Environment (STBE) presents selected high quality papers that were presented at the 15th International Refrigeration and Air Conditioning Conference held at Purdue University during July 14-17 2014. All papers went through the additional review before being finally accepted for publication in this special issue of Science and Technology and the Built Environment. Altogether 20 papers made to this special issue that cover a wide range of topics, including advancements in alternative refrigerants, heat exchangers/heat transfer, nano-fluids, systems design and optimization and modeling approaches. Although CO 2 may perhaps have beenmore » the most researched and popular refrigerant in the past decade, R32 is being seriously considered lately as an alternative and environmentally friendly refrigerant for small systems due to its low Global Warming Potential (GWP).« less

Advances in refrigeration and heat transfer engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bansal, Pradeep; Cremaschi, Prof. Lorenzo

This special edition of Science and Technology for the Built Environment (STBE) presents selected high quality papers that were presented at the 15th International Refrigeration and Air Conditioning Conference held at Purdue University during July 14-17 2014. All papers went through the additional review before being finally accepted for publication in this special issue of Science and Technology and the Built Environment. Altogether 20 papers made to this special issue that cover a wide range of topics, including advancements in alternative refrigerants, heat exchangers/heat transfer, nano-fluids, systems design and optimization and modeling approaches. Although CO 2 may perhaps have beenmore » the most researched and popular refrigerant in the past decade, R32 is being seriously considered lately as an alternative and environmentally friendly refrigerant for small systems due to its low Global Warming Potential (GWP).« less

Addressing the human factors issues associated with control room modifications

DOE Office of Scientific and Technical Information (OSTI.GOV)

O`Hara, J.; Stubler, W.; Kramer, J.

1998-03-01

Advanced human-system interface (HSI) technology is being integrated into existing nuclear plants as part of plant modifications and upgrades. The result of this trend is that hybrid HSIs are created, i.e., HSIs containing a mixture of conventional (analog) and advanced (digital) technology. The purpose of the present research is to define the potential effects of hybrid HSIs on personnel performance and plant safety and to develop human factors guidance for safety reviews of them where necessary. In support of this objective, human factors issues associated with hybrid HSIs were identified. The issues were evaluated for their potential significance to plantmore » safety, i.e., their human performance concerns have the potential to compromise plant safety. The issues were then prioritized and a subset was selected for design review guidance development.« less

Genetic Modification of Short Rotation Poplar Biomass Feedstock for Efficient Conversion to Ethanol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dinus, R.J.

2000-08-30

The Bioenergy Feedstock Development Program, Environmental Sciences Division, Oak Ridge National Laboratory is developing poplars (Populus species and hybrids) as sources of renewable energy, i.e., ethanol. Notable increases in adaptability, volume productivity, and pest/stress resistance have been achieved via classical selection and breeding and intensified cultural practices. Significant advances have also been made in the efficiencies of harvesting and handling systems. Given these and anticipated accomplishments, program leaders are considering shifting some attention to genetically modifying feedstock physical and chemical properties, so as to improve the efficiency with which feedstocks can be converted to ethanol. This report provides an in-depthmore » review and synthesis of opportunities for and feasibilities of genetically modifying feedstock qualities via classical selection and breeding, marker-aided selection and breeding, and genetic transformation. Information was collected by analysis of the literature, with emphasis on that published since 1995, and interviews with prominent scientists, breeders, and growers. Poplar research is well advanced, and literature is abundant. The report therefore primarily reflects advances in poplars, but data from other species, particularly other shortrotation hardwoods, are incorporated to fill gaps. An executive summary and recommendations for research, development, and technology transfer are provided immediately after the table of contents. The first major section of the report describes processes most likely to be used for conversion of poplar biomass to ethanol, the various physical and chemical properties of poplar feedstocks, and how such properties are expected to affect process efficiency. The need is stressed for improved understanding of the impact of change on both overall process and individual process step efficiencies. The second part documents advances in trait measurement instrumentation and methodology. The importance of these and future developments is emphasized, since trait measurement constitutes the largest cost associated with adding additional traits to improvement efforts, regardless of genetic approach. In subsequent sections, recent and projected advances in classical selection and breeding, marker-aided selection, and genetic transformation are documented and used to evaluate the feasibility of individual approaches. Interviews with specialists engaged in research and development on each approach were given particular emphasis in gauging feasibilities and defining future needs and directions. Summaries of important findings and major conclusions are presented at the end of individual sections. Closing portions describe the targeted workshop, conducted in December 1999 and list interviewees and literature cited in the text. Information obtained at the workshop was used to improve accuracy, refine conclusions, and recommend priorities for future research, development, and technology transfer.« less

A Study on Advanced Lithium-Based Battery Cell Chemistries to Enhance Lunar Exploration Missions

NASA Technical Reports Server (NTRS)

Reid, Concha M.; Bennett, William R.

2010-01-01

NASAs Exploration Technology Development Program (ETDP) Energy Storage Project conducted an advanced lithium-based battery chemistry feasibility study to determine the best advanced chemistry to develop for the Altair Lunar Lander and the Extravehicular Activities (EVA) advanced Lunar surface spacesuit. These customers require safe, reliable batteries with extremely high specific energy as compared to state-of-the-art. The specific energy goals for the development project are 220 watt-hours per kilogram (Wh/kg) delivered at the battery-level at 0 degrees Celsius ( C) at a C/10 discharge rate. Continuous discharge rates between C/5 and C/2, operation between 0 and 30 C and 200 cycles are targeted. Electrode materials that were considered include layered metal oxides, spinel oxides, and olivine-type cathode materials, and lithium metal, lithium alloy, and silicon-based composite anode materials. Advanced cell chemistry options were evaluated with respect to multiple quantitative and qualitative attributes while considering their projected performance at the end of the available development timeframe. Following a rigorous ranking process, a chemistry that combines a lithiated nickel manganese cobalt oxide Li(LiNMC)O2 cathode with a silicon-based composite anode was selected as the technology that can potentially offer the best combination of safety, specific energy, energy density, and likelihood of success.

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

10 CFR 611.202 - Advanced Technology Vehicle Manufacturing Facility Award Program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Advanced Technology Vehicle Manufacturing Facility Award... TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Facility/Funding Awards § 611.202 Advanced Technology Vehicle Manufacturing Facility Award Program. DOE may issue, under the Advanced Technology Vehicle...

Furthering the reliable and valid measurement of mental health screening, diagnoses, treatment and outcomes through health information technology.

PubMed

Haberer, Jessica E; Trabin, Tom; Klinkman, Michael

2013-01-01

Measurement of mental health is challenging; however, many solutions may be found through the use of health information technology. This article reviews current approaches to measuring mental health, focusing on screening, diagnosis, treatment, and outcomes. It then identifies several key areas in which health information technology may advance the field and provide reliable and valid measurements that are readily available to and manageable for providers, as well as acceptable, feasible, and sustainable for selected populations. Although new technologies must overcome many challenges, including privacy, efficiency, cost, and scalability, it is an exciting and fast-growing field with many potential applications and clinical benefit. Copyright © 2013 Elsevier Inc. All rights reserved.

Advanced organic composite materials for aircraft structures: Future program

NASA Technical Reports Server (NTRS)

1987-01-01

Revolutionary advances in structural materials have been responsible for revolutionary changes in all fields of engineering. These advances have had and are still having a significant impact on aircraft design and performance. Composites are engineered materials. Their properties are tailored through the use of a mix or blend of different constituents to maximize selected properties of strength and/or stiffness at reduced weights. More than 20 years have passed since the potentials of filamentary composite materials were identified. During the 1970s much lower cost carbon filaments became a reality and gradually designers turned from boron to carbon composites. Despite progress in this field, filamentary composites still have significant unfulfilled potential for increasing aircraft productivity; the rendering of advanced organic composite materials into production aircraft structures was disappointingly slow. Why this is and research and technology development actions that will assist in accelerating the application of advanced organic composites to production aircraft is discussed.

Technology readiness levels and technology status for selected long term/high payoff technologies on the RLV program

NASA Technical Reports Server (NTRS)

Rosmait, Russell L.

1996-01-01

The development of a new space transportation system in a climate of constant budget cuts and staff reductions can be and is a difficult task. It is no secret that NASA's current launching system consumes a very large portion of NASA funding and requires a large army of people to operate & maintain the system. The new Reusable Launch Vehicle (RLV) project and it's programs are faced with a monumental task of making the cost of access to space dramatically lower and more efficient than NASA's current system. With pressures from congressional budget cutters and also increased competition and loss of market share from international agencies RLV's first priority is to develop a 'low-cost, reliable transportation to earth orbit.' One of the RLV's major focus in achieving low-cost, reliable transportation to earth orbit is to rely on the maturing of advanced technologies. The technologies for the RLV are numerous and varied. Trying to assess their current status, within the RLV development program is paramount. There are several ways to assess these technologies. One way is through the use of Technology Readiness Levels (TRL's). This project focused on establishing current (summer 95) 'worst case' TRL's for six selected technologies that are under consideration for use within the RLV program. The six technologies evaluated were Concurrent Engineering, Embedded Sensor Technology, Rapid Prototyping, Friction Stir Welding, Thermal Spray Coatings, and VPPA Welding.

A survey of advanced battery systems for space applications

NASA Technical Reports Server (NTRS)

Attia, Alan I.

1989-01-01

The results of a survey on advanced secondary battery systems for space applications are presented. The objectives were: to identify advanced battery systems capable of meeting the requirements of various types of space missions, with significant advantages over currently available batteries, to obtain an accurate estimate of the anticipated improvements of these advanced systems, and to obtain a consensus for the selection of systems most likely to yield the desired improvements. Few advanced systems are likely to exceed a specific energy of 150 Wh/kg and meet the additional requirements of safety and reliability within the next 15 years. The few that have this potential are: (1) regenerative fuel cells, both alkaline and solid polymer electrolyte (SPE) types for large power systems; (2) lithium-intercalatable cathodes, particularly the metal ozides intercalatable cathodes (MnO2 or CoO2), with applications limited to small spacecrafts requiring limited cycle life and low power levels; (3) lithium molten salt systems (e.g., LiAl-FeS2); and (4) Na/beta Alumina/Sulfur or metal chlorides cells. Likely technological advances that would enhance the performance of all the above systems are also identified, in particular: improved bifunctional oxygen electrodes; improved manufacturing technology for thin film lithium electrodes in combination with polymeric electrolytes; improved seals for the lithium molten salt cells; and improved ceramics for sodium/solid electrolyte cells.

The impact of biotechnological advances on the future of US bioenergy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davison, Brian H.; Brandt, Craig C.; Guss, Adam M.

Modern biotechnology has the potential to substantially advance the feasibility, structure, and efficiency of future biofuel supply chains. Advances might be direct or indirect. A direct advance would be improving the efficiency of biochemical conversion processes and feedstock production. Direct advances in processing may involve developing improved enzymes and bacteria to convert lignocellulosic feedstocks to ethanol. Progress in feedstock production could include enhancing crop yields via genetic modification or the selection of specific natural variants and breeds. Other direct results of biotechnology might increase the production of fungible biofuels and bioproducts, which would impact the supply chain. Indirect advances mightmore » include modifications to dedicated bioenergy crops that enable them to grow on marginal lands rather than land needed for food production. This study assesses the feasibility and advantages of near-future (10-year) biotechnological developments for a US biomass-based supply chain for bioenergy production. We assume a simplified supply chain of feedstock, logistics and land use, conversion, and products and utilization. The primary focus is how likely developments in feedstock production and conversion technologies will impact bioenergy and biofuels in the USA; a secondary focus is other innovative uses of biotechnologies in the energy arenas. The assessment addresses near-term biofuels based on starch, sugar, and cellulosic feedstocks and considers some longer-term options, such as oil-crop and algal technologies.« less

The impact of biotechnological advances on the future of US bioenergy

DOE PAGES

Davison, Brian H.; Brandt, Craig C.; Guss, Adam M.; ...

2015-05-14

Modern biotechnology has the potential to substantially advance the feasibility, structure, and efficiency of future biofuel supply chains. Advances might be direct or indirect. A direct advance would be improving the efficiency of biochemical conversion processes and feedstock production. Direct advances in processing may involve developing improved enzymes and bacteria to convert lignocellulosic feedstocks to ethanol. Progress in feedstock production could include enhancing crop yields via genetic modification or the selection of specific natural variants and breeds. Other direct results of biotechnology might increase the production of fungible biofuels and bioproducts, which would impact the supply chain. Indirect advances mightmore » include modifications to dedicated bioenergy crops that enable them to grow on marginal lands rather than land needed for food production. This study assesses the feasibility and advantages of near-future (10-year) biotechnological developments for a US biomass-based supply chain for bioenergy production. We assume a simplified supply chain of feedstock, logistics and land use, conversion, and products and utilization. The primary focus is how likely developments in feedstock production and conversion technologies will impact bioenergy and biofuels in the USA; a secondary focus is other innovative uses of biotechnologies in the energy arenas. The assessment addresses near-term biofuels based on starch, sugar, and cellulosic feedstocks and considers some longer-term options, such as oil-crop and algal technologies.« less

Considerations for a Next Generation UV/Optical Space Telescope

NASA Technical Reports Server (NTRS)

Nein, M. E.; Morgan, S. H.

1989-01-01

During the past 25 years, a remarkable scientific revolution, has occurred in astrophysics as a result of convergence on two advancing fronts. First, instruments and telescopes have been developed to make sensitive measurements throughout the entire electromagnetic spectrum. Secondly, access to space has permitted observations above the obscuring and distorting "dirty window" of our atmosphere. Beginning around the middle of the next decade, a third major path - the availability of the permanently manned Space Station Freedom - will join with the earlier two capabilities, to not only continue this revolution, but to accelerate the quest for answers about the universe that have puzzled mankind for centuries. Beyond Earth-orbit, NASA is actively studying the possibility of a return to the Moon, which would provide a valuable platform for astrophysics observations during the next century. The studies discussed in this paper indicate that the technology requirements associated with the transportation to orbit and the assembly of these telescopes in orbit are major driving forces in the selection of generic design concepts. Ultimately, optical advances which are now becoming available through advanced manufacturing must be matched by technology advances in orbital operations, system modularization, and assembly by man and machine.

System design impacts on optimization of the advanced radioisotope power system (ARPS) AMTEC cell

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendricks, T.J.; Huang, C.

1998-07-01

Several NASA deep space missions require Advanced Radioisotope Power Systems (ARPS) to supply spacecraft power for various internal functions and mission instruments and experiments. AMTEC (Alkali-Metal Thermal-Electric Conversion) power conversion is the DOE-selected technology for an advanced, next- generation RPS to power these spacecraft. Advanced Modular Power Systems, Inc. (AMPS) has begun investigating the design of an AMTEC-based ARPS using the General Purpose Heat Source (GPHS) and the latest PX-5 AMTEC cell technology with refractory materials in critical components. This paper presents and discusses the system design methodology, and results of important system design tradeoffs and system design impacts onmore » the ARPS AMTEC cell design. This work investigated dual 2-GPHS system configurations and 4-GPHS system configurations with 16 side-mounted AMTEC cells operating at beginning-of-mission (BOM) and end-of-mission (EOM) GPHS heat dissipation conditions. Current design studies indicate using a refractory material AMTEC cell with 8-BASE tubes, 5.0 inches long, and 1.75 inches diameter in the 4-GPHS system configuration is the strongest design candidate to satisfy system performance requirements.« less

Medical sociology and technology: critical engagements.

PubMed

Casper, Monica J; Morrison, Daniel R

2010-01-01

In this selective review of the literature on medical sociology's engagement with technology, we outline the concurrent developments of the American Sociological Association section on medicine and advances in medical treatment. We then describe theoretical and epistemological issues with scholars' treatment of technology in medicine. Using symbolic interactionist concepts, as well as work from the interdisciplinary field of science and technology studies, we review and synthesize critical connections in and across sociology's intellectual relationship with medical technology. Next, we discuss key findings in these literatures, noting a shift from a focus on the effects of technology on practice to a reconfiguration of human bodies. We also look toward the future, focusing on connections between technoscientific identities and embodied health movements. Finally, we call for greater engagement by medical sociologists in studying medical technology and the process of policy-making--two areas central to debates in health economics and public policy.

Youth, Technology and HIV: Recent Advances and Future Directions

PubMed Central

Hightow-Weidman, Lisa B.; Muessig, Kathryn E.; Bauermeister, Jose; Zhang, Chen; LeGrand, Sara

2015-01-01

Technology, including mobile technologies and social media, offers powerful tools to reach, engage, and retain youth and young adults in HIV prevention and care interventions both in the United States and globally. In this report we focus on HIV, technology, and youth, presenting a synthesis of recently published (Jan 2014-May 2015) observational and experimental studies relevant for understanding and intervening on HIV risk, prevention and care. We present findings from a selection of the 66 relevant citations identified, highlighting studies that demonstrate a novel approach to technology interventions among youth in regard to content, delivery, target population or public health impact. We discuss current trends globally and in the US in how youth are using technology, as well as emergent research issues in this field – including the need for new theories for developing technology-based HIV interventions and new metrics of engagement, exposure, and evaluation. PMID:26385582

Variable-cycle engines for supersonic cruising aircraft

NASA Technical Reports Server (NTRS)

Willis, E. A.; Welliver, A. D.

1976-01-01

The paper reviews the evolution and current status of selected recent variable-cycle engine (VCE) studies and describes how the results are influenced by airplane requirements. The engine/airplane studies are intended to identify promising VCE concepts, simplify their designs and identify the potential benefits in terms of aircraft performance. This includes range, noise, emissions, and the time and effort it may require to ensure technical readiness of sufficient depth to satisfy reasonable economic, performance, and environmental constraints. A brief overview of closely-related, on-going technology programs in acoustics and exhaust emissions is presented. It is shown that realistic technology advancements in critical areas combined with well matched aircraft and selected VCE concepts can lead to significantly improved economic and environmental performance relative to first-generation SST predictions.

Optical coating technology for the EUV

NASA Technical Reports Server (NTRS)

Osantowski, J. F.; Keski-Kuha, R. A. M.; Herzig, H.; Toft, A. R.; Gum, J. S.; Fleetwood, C. M.

1991-01-01

Advances in optical coating and materials technology are one of the key motivators for the development of missions such as the Far Ultraviolet Spectroscopic Explorer recently selected by NASA for an Explorer class mission in the mid 1990's. The performance of a range of candidate coatings are reviewed for normal-incidence and glancing-incidence applications, and attention is given to strengths and problem areas for their use in space. The importance of recent developments in multilayer films, chemical-vapor deposited SiC (CVD-SiC) mirrors, and SiC films are discussed in the context of EUV instrumentation design. For example, the choice of optical coatings is a design driver for the selection of the average glancing angle for the FUSE telescope, and impacts efficiency, short-wavelength cut-off, and physical size.

A Review of Biorefinery Separations for Bioproduct Production via Thermocatalytic Processing.

PubMed

Nguyen, Hannah; DeJaco, Robert F; Mittal, Nitish; Siepmann, J Ilja; Tsapatsis, Michael; Snyder, Mark A; Fan, Wei; Saha, Basudeb; Vlachos, Dionisios G

2017-06-07

With technological advancement of thermocatalytic processes for valorizing renewable biomass carbon, development of effective separation technologies for selective recovery of bioproducts from complex reaction media and their purification becomes essential. The high thermal sensitivity of biomass intermediates and their low volatility and high reactivity, along with the use of dilute solutions, make the bioproducts separations energy intensive and expensive. Novel separation techniques, including solvent extraction in biphasic systems and reactive adsorption using zeolite and carbon sorbents, membranes, and chromatography, have been developed. In parallel with experimental efforts, multiscale simulations have been reported for predicting solvent selection and adsorption separation. We discuss various separations that are potentially valuable to future biorefineries and the factors controlling separation performance. Particular emphasis is given to current gaps and opportunities for future development.

Recovery of Rare Earths, Precious Metals and Other Critical Materials from Geothermal Waters with Advanced Sorbent Structures

DOE Data Explorer

Pamela M. Kinsey

2015-09-30

The work evaluates, develops and demonstrates flexible, scalable mineral extraction technology for geothermal brines based upon solid phase sorbent materials with a specific focus upon rare earth elements (REEs). The selected organic and inorganic sorbent materials demonstrated high performance for collection of trace REEs, precious and valuable metals. The nanostructured materials typically performed better than commercially available sorbents. Data contains organic and inorganic sorbent removal efficiency, Sharkey Hot Springs (Idaho) water chemsitry analysis, and rare earth removal efficiency from select sorbents.

Payload crew interface design criteria and techniques. Task 1: Inflight operations and training for payloads. [space shuttles

NASA Technical Reports Server (NTRS)

Carmean, W. D.; Hitz, F. R.

1976-01-01

Guidelines are developed for use in control and display panel design for payload operations performed on the aft flight deck of the orbiter. Preliminary payload procedures are defined. Crew operational concepts are developed. Payloads selected for operational simulations were the shuttle UV optical telescope (SUOT), the deep sky UV survey telescope (DUST), and the shuttle UV stellar spectrograph (SUSS). The advanced technology laboratory payload consisting of 11 experiments was selected for a detailed evaluation because of the availability of operational data and its operational complexity.

Microalgal process-monitoring based on high-selectivity spectroscopy tools: status and future perspectives.

PubMed

Podevin, Michael; Fotidis, Ioannis A; Angelidaki, Irini

2018-08-01

Microalgae are well known for their ability to accumulate lipids intracellularly, which can be used for biofuels and mitigate CO 2 emissions. However, due to economic challenges, microalgae bioprocesses have maneuvered towards the simultaneous production of food, feed, fuel, and various high-value chemicals in a biorefinery concept. On-line and in-line monitoring of macromolecules such as lipids, proteins, carbohydrates, and high-value pigments will be more critical to maintain product quality and consistency for downstream processing in a biorefinery to maintain and valorize these markets. The main contribution of this review is to present current and prospective advances of on-line and in-line process analytical technology (PAT), with high-selectivity - the capability of monitoring several analytes simultaneously - in the interest of improving product quality, productivity, and process automation of a microalgal biorefinery. The high-selectivity PAT under consideration are mid-infrared (MIR), near-infrared (NIR), and Raman vibrational spectroscopies. The current review contains a critical assessment of these technologies in the context of recent advances in software and hardware in order to move microalgae production towards process automation through multivariate process control (MVPC) and software sensors trained on "big data". The paper will also include a comprehensive overview of off-line implementations of vibrational spectroscopy in microalgal research as it pertains to spectral interpretation and process automation to aid and motivate development.

Coal without carbon: an investment plan for federal action

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pettus, A.; Tatsutani, M.

2009-09-15

This study examines several technologies for CCS that are not currently receiving adequate development support but that could - in the right policy environment - provide the kind of significant cost reductions (and significant improvements in efficiency) that could greatly accelerate broad, economically attractive CCS deployment. Clean Air Task Force selected these technology areas (though not the technologies themselves) and solicited reports from experts in each field to explore how these technologies might fit into a broader CCS deployment strategy. Each expert was asked to develop a research, development, and demonstration (RD&D) 'road map' that could efficiently move each technologymore » from the laboratory into the commercial mainstream. Because the chapter authors are either technical experts or commercial players and are not, for the most part, energy policy experts, subsequent work will translate their RD&D recommendations into actionable policy proposals. The heart of this report consists of four chapters on advanced coal and CCS technologies: underground coal gasification (UCG), written by Julio Friedmann at Lawrence Livermore National Laboratory; Next generation coal gasification (surface-based gasification) led by Eric Redman at Summit Power Group; Advanced technologies for post-combustion capture (PCC) of CO{sub 2}, led by Howard Herzog at Massachusetts Institute of Technology; and RD&D to speed commercialization of geological CO{sub 2} sequestration (GCS), led by Julio Friedmann. 12 refs., 5 figs., 2 tabs.« less

Aptamer-Functionalized Nanoparticles for Medical Applications: Challenges and Opportunities

PubMed Central

Xiao, Zeyu; Farokhzad, Omid C.

2012-01-01

With advances in aptamer selection technologies and nanomedicine, aptamer-functionalized nanoparticles are being explored as promising platforms for targeted therapeutic and diagnostic applications. In this Perspective, we outline recent progress in this field, as exemplified by Bamrungsap et al. in this issue of ACS Nano. Furthermore, we highlight the challenges and opportunities in translating current proof-of-concept designs into in vivo applications, with emphasis on the intrinsic properties of aptamers and their interplay with nanoparticles. With continuous efforts, we expect aptamer-functionalized nanoparticles to advance from preclinical into clinical development for further evaluation. PMID:22574989

Comparison of alternate fuels for aircraft

NASA Technical Reports Server (NTRS)

Witcofski, R. D.

1979-01-01

A comparison of candidate alternate fuels for aircraft is presented. The fuels discussed include liquid hydrogen, liquid methane, and synthetic aviation kerosene. Each fuel is evaluated from the standpoint of production, transmission, airport storage and distribution facilities, and use in aircraft. Technology deficient areas for cryogenic fuels, which should be advanced prior to the introduction of the fuels into the aviation industry, are identified, as are the cost and energy penalties associated with not achieving those advances. Environmental emissions and safety aspects of fuel selection are discussed. A detailed description of the various fuel production and liquefaction processes and their efficiencies and economics is given.

CFD Analysis in Advance of the NASA Juncture Flow Experiment

NASA Technical Reports Server (NTRS)

Lee, H. C.; Pulliam, T. H.; Neuhart, D. H.; Kegerise, M. A.

2017-01-01

NASA through its Transformational Tools and Technologies Project (TTT) under the Advanced Air Vehicle Program, is supporting a substantial effort to investigate the formation and origin of separation bubbles found on wing-body juncture zones. The flow behavior in these regions is highly complex, difficult to measure experimentally, and challenging to model numerically. Multiple wing configurations were designed and evaluated using Computational Fluid Dynamics (CFD), and a series of wind tunnel risk reduction tests were performed to further down-select the candidates for the final experiment. This paper documents the CFD analysis done in conjunction with the 6 percent scale risk reduction experiment performed in NASA Langley's 14- by 22-Foot Subsonic Tunnel. The combined CFD and wind tunnel results ultimately helped the Juncture Flow committee select the wing configurations for the final experiment.

Monitoring Of Landslide Hazard In Selected Areas Of Uzbekistan

NASA Astrophysics Data System (ADS)

Lazecky, Milan; Balaha, Pavel; Khasankhanova, Gulchekhra; Minchenko, Venscelas

2013-12-01

Republic of Uzbekistan is situated in the heart of Central Asia. Dangerous phenomena such as drought, flooding, mud flows, landslides and others, that are becoming frequent in conditions of climate changes, increase instability of an agricultural production, and threaten rural livelihoods. In connection with weather and climate natural disasters, these phenomena become reasons of declining food production, water contamination, and economical damages. Within the Project granted by NATO: Science for Peace and Security programme, modern advanced remote sensing technologies will be applied to perform large scale monitoring of (early) slope deformations, including Satellite SAR Interferometry (InSAR) techniques, Ground Laser Scanning for in-situ refinement of detected movements or Multibeam Echosounding for monitoring slope deformation advancement into water objects. First results involving InSAR processing of selected sites in Uzbekistan are presented within this contribution.

Computer Game

NASA Technical Reports Server (NTRS)

1992-01-01

Using NASA studies of advanced lunar exploration and colonization, KDT Industries, Inc. and Wesson International have developed MOONBASE, a computer game. The player, or team commander, must build and operate a lunar base using NASA technology. He has 10 years to explore the surface, select a site and assemble structures brought from Earth into an efficient base. The game was introduced in 1991 by Texas Space Grant Consortium.

Proceedings of the 1994 international meeting on reduced enrichment for research and test reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-08-01

This meeting brought together participants in the international effort to minimize and eventually eliminate the use of highly enriched uranium in civilian nuclear programs. Papers cover the following topics: National programs; fuel cycle; nuclear fuels; analyses; advanced reactors; and reactor conversions. Selected papers have been indexed separately for inclusion to the Energy Science and Technology Database.

Design study of test models of maneuvering aircraft configurations for the National Transonic Facility (NTF)

NASA Technical Reports Server (NTRS)

Griffin, S. A.; Madsen, A. P.; Mcclain, A. A.

1984-01-01

The feasibility of designing advanced technology, highly maneuverable, fighter aircraft models to achieve full scale Reynolds number in the National Transonic Facility (NTF) is examined. Each of the selected configurations are tested for aeroelastic effects through the use of force and pressure data. A review of materials and material processes is also included.

Selecting Effective Indicators. College Readiness Indicator Systems (CRIS) Resource Series

ERIC Educational Resources Information Center

University of Chicago Consortium on Chicago School Research, 2014

2014-01-01

The use of data to inform decisionmaking and practice at the school and district levels is now a common feature of reform efforts. Advances in districts' technological capacities have produced data systems that allow a flow of data to and from schools, often to the point of creating an overwhelming flood of information. To make the flow of…

Analyzing the glass ceiling effect among radiologic technologists.

PubMed

Belinsky, Susan B; Blagg, James D

2011-01-01

The literature has suggested that advancement within politics, academia and the health professions is influenced by gender. Purpose The authors conducted a survey to determine whether advancement was equal by gender in the radiologic science disciplines of nuclear medicine technology, radiation therapy and radiography. The survey was mailed to 900 subjects, 300 from each discipline. The discipline groups were further stratified by initial year of American Registry of Radiologic Technology certification; the authors selected 100 subjects from each discipline who initially were certified in 1978, 100 in 1988 and 100 in 1998. Approximately 33% of those selected responded. The findings of the study provided no evidence that men are promoted differentially than women. Women perceived that men were paid more for the same work. It appears that gender bias is pervasive outside of promotion decisions and, indeed, that some illegal actions (eg, sexual harassment, inappropriate gender-related interview questions) take place in radiologic science clinical settings. It is hoped that this study will set a baseline for future research on whether there is a glass ceiling effect in radiologic clinical practice and stimulate discussion of the importance of equal opportunity regardless of gender.

Effects of advanced selection methods on sperm quality and ART outcome.

PubMed

Yetunde, I; Vasiliki, M

2013-10-01

In assisted reproductive technology (ART), the role of spermatozoa has evolved over the years. In the past, early methods of selecting sperm for ART only focused on selecting motile and morphologically normal appearing sperm. It has become evident that these methods are inefficient in identifying the most suitable sperm for fertilization. Novel methods have thus been created to identify highly motile, morphologically normal, viable non-apoptotic spermatozoa with intact membranes and high DNA integrity for use in ART. These advanced methods of selection utilize our knowledge of unique characteristics of sperm, such as sperm surface charge, the presence of hyaluronic acid binding sites on sperm, sperm ultramorphology, markers of apoptosis and zona pellucida binding on sperm. These methods have shown potential promise in improving ART outcomes. Future developments may include Raman spectroscopy, confocal light absorption and scattering spectroscopic microscopy, and polarization microscopy. While these novel techniques have potential, they come with a cost burden and further studies are required to demonstrate their impact on ART outcomes. Furthermore, clinicians and human reproductive scientists need to continue to gather knowledge about human fertilization and determine the most physiological methods of sperm selection.

Stimulating Innovation and Accelerating the Development of Complex and Slowly Maturing Technologies Through Advanced Technology Prize Competitions

DTIC Science & Technology

2007-06-15

technology prize competitions have been used since the 18th century to spur innovation and advance the development of complex and slowly maturing disruptive ... technologies The Defense Advanced Research Projects Agency (DARPA) has used advanced technology competitions in 2004 and 2005 to rapidly accelerate the

System Architecture Modeling for Technology Portfolio Management using ATLAS

NASA Technical Reports Server (NTRS)

Thompson, Robert W.; O'Neil, Daniel A.

2006-01-01

Strategic planners and technology portfolio managers have traditionally relied on consensus-based tools, such as Analytical Hierarchy Process (AHP) and Quality Function Deployment (QFD) in planning the funding of technology development. While useful to a certain extent, these tools are limited in the ability to fully quantify the impact of a technology choice on system mass, system reliability, project schedule, and lifecycle cost. The Advanced Technology Lifecycle Analysis System (ATLAS) aims to provide strategic planners a decision support tool for analyzing technology selections within a Space Exploration Architecture (SEA). Using ATLAS, strategic planners can select physics-based system models from a library, configure the systems with technologies and performance parameters, and plan the deployment of a SEA. Key parameters for current and future technologies have been collected from subject-matter experts and other documented sources in the Technology Tool Box (TTB). ATLAS can be used to compare the technical feasibility and economic viability of a set of technology choices for one SEA, and compare it against another set of technology choices or another SEA. System architecture modeling in ATLAS is a multi-step process. First, the modeler defines the system level requirements. Second, the modeler identifies technologies of interest whose impact on an SEA. Third, the system modeling team creates models of architecture elements (e.g. launch vehicles, in-space transfer vehicles, crew vehicles) if they are not already in the model library. Finally, the architecture modeler develops a script for the ATLAS tool to run, and the results for comparison are generated.

Preliminary Framework for Human-Automation Collaboration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oxstrand, Johanna Helene; Le Blanc, Katya Lee; Spielman, Zachary Alexander

The Department of Energy’s Advanced Reactor Technologies Program sponsors research, development and deployment activities through its Next Generation Nuclear Plant, Advanced Reactor Concepts, and Advanced Small Modular Reactor (aSMR) Programs to promote safety, technical, economical, and environmental advancements of innovative Generation IV nuclear energy technologies. The Human Automation Collaboration (HAC) Research Project is located under the aSMR Program, which identifies developing advanced instrumentation and controls and human-machine interfaces as one of four key research areas. It is expected that the new nuclear power plant designs will employ technology significantly more advanced than the analog systems in the existing reactor fleetmore » as well as utilizing automation to a greater extent. Moving towards more advanced technology and more automation does not necessary imply more efficient and safer operation of the plant. Instead, a number of concerns about how these technologies will affect human performance and the overall safety of the plant need to be addressed. More specifically, it is important to investigate how the operator and the automation work as a team to ensure effective and safe plant operation, also known as the human-automation collaboration (HAC). The focus of the HAC research is to understand how various characteristics of automation (such as its reliability, processes, and modes) effect an operator’s use and awareness of plant conditions. In other words, the research team investigates how to best design the collaboration between the operators and the automated systems in a manner that has the greatest positive impact on overall plant performance and reliability. This report addresses the Department of Energy milestone M4AT-15IN2302054, Complete Preliminary Framework for Human-Automation Collaboration, by discussing the two phased development of a preliminary HAC framework. The framework developed in the first phase was used as the basis for selecting topics to be investigated in more detail. The results and insights gained from the in-depth studies conducted during the second phase were used to revise the framework. This report describes the basis for the framework developed in phase 1, the changes made to the framework in phase 2, and the basis for the changes. Additional research needs are identified and presented in the last section of the report.« less

GRC Supporting Technology for NASA's Advanced Stirling Radioisotope Generator (ASRG)

NASA Technical Reports Server (NTRS)

Schreiber, Jeffrey G.; Thieme, Lanny G.

2008-01-01

From 1999 to 2006, the NASA Glenn Research Center (GRC) supported a NASA project to develop a high-efficiency, nominal 110-We Stirling Radioisotope Generator (SRG110) for potential use on NASA missions. Lockheed Martin was selected as the System Integration Contractor for the SRG110, under contract to the Department of Energy (DOE). The potential applications included deep space missions, and Mars rovers. The project was redirected in 2006 to make use of the Advanced Stirling Convertor (ASC) that was being developed by Sunpower, Inc. under contract to GRC, which would reduce the mass of the generator and increase the power output. This change would approximately double the specific power and result in the Advanced Stirling Radioisotope Generator (ASRG). The SRG110 supporting technology effort at GRC was replanned to support the integration of the Sunpower convertor and the ASRG. This paper describes the ASRG supporting technology effort at GRC and provides details of the contributions in some of the key areas. The GRC tasks include convertor extended-operation testing in air and in thermal vacuum environments, heater head life assessment, materials studies, permanent magnet characterization and aging tests, structural dynamics testing, electromagnetic interference and electromagnetic compatibility characterization, evaluation of organic materials, reliability studies, and analysis to support controller development.

A new vision of the post-NIST civil infrastructure program: the challenges of next-generation construction materials and processes

NASA Astrophysics Data System (ADS)

Wu, H. Felix; Wan, Yan

2014-03-01

Our nation's infrastructural systems are crumbling. The deteriorating process grows over time. The physical aging of these vital facilities and the remediation of their current critical state pose a key societal challenge to the United States. Current sensing technologies, while well developed in controlled laboratory environments, have not yet yielded tools for producing real-time, in-situ data that are adequately comprehensible for infrastructure decision-makers. The need for advanced sensing technologies is national because every municipality and state in the nation faces infrastructure management challenges. The need is critical because portions of infrastructure are reaching the end of their life-spans and there are few cost-effective means to monitor infrastructure integrity and to prioritize the renovation and replacement of infrastructure elements. New advanced sensing technologies that produce cost-effective inspection and real-time monitoring data, and that can also help or aid in meaningful interpretation of the acquired data, therefore will enhance the safety in regard to the public on structural integrity by issuing timely and accurate alert data for effective maintenance to avoid disasters happening. New advanced sensing technologies also allow more informed management of infrastructural investments by avoiding premature replacement of infrastructure and identifying those structures in need of immediate action to prevent from catastrophic failure. Infrastructure management requires that once a structural defect is detected, an economical and efficient repair be made. Advancing the technologies of repairing infrastructure elements in contact with water, road salt, and subjected to thermal changes requires innovative research to significantly extend the service life of repairs, lower the costs of repairs, and provide repair technologies that are suitable for a wide range of conditions. All these new technologies will provide increased lifetimes, security, and safety of elements of critical infrastructure for the Nation's already deteriorating civil infrastructure. It is envisioned that the Nation should look far beyond: not only should we efficiently and effectively address current problems of the aging infrastructure, but we must also further develop next-generation construction materials and processes for new construction. To accomplish this ambitious goal, we must include process efficiency that will help select the most reliable and cost-effective materials in construction processes; performance and cost will be the prime consideration for selections construction materials based on life-cycle cost and materials performance; energy efficiency will drive reduced energy consumption from current levels by 50 % per unit of output; and environmental responsiveness will achieve net-zero waste from construction materials and its constituents. Should it be successfully implemented, we will transform the current 21st century infrastructure systems to enable the vital functioning of society and improve competitiveness of the economy to ensure that our quality of life remains high.

Development of an automated ammunition processing system for battlefield use

DOE Office of Scientific and Technical Information (OSTI.GOV)

Speaks, D.M.; Chesser, J.B.; Lloyd, P.D.

1995-03-01

The Future Armored Resupply Vehicle (FARV) will be the companion ammunition resupply vehicle to the Advanced Field Artillery System (AFAS). These systems are currently being investigated by the US Army for future acquisition. The FARV will sustain the AFAS with ammunition and fuel and will significantly increase capabilities over current resupply vehicles. Currently ammunition is transferred to field artillery almost entirely by hand. The level of automation to be included into the FARV is still under consideration. At the request of the US Army`s Project Manager, AFAS/FARV, Oak Ridge National Laboratory (ORNL) identified and evaluated various concepts for the automatedmore » upload, processing, storage, and delivery equipment for the FARV. ORNL, working with the sponsor, established basic requirements and assumptions for concept development and the methodology for concept selection. A preliminary concept has been selected, and the associated critical technologies have been identified. ORNL has provided technology demonstrations of many of these critical technologies. A technology demonstrator which incorporates all individual components into a total process demonstration is planned for late FY 1995.« less

Regenerative Fuel Cell Power Systems for Lunar and Martian Surface Exploration

NASA Technical Reports Server (NTRS)

Guzik, Monica C.; Jakupca, Ian J.; Gilligan, Ryan P.; Bennett, William R.; Smith, Phillip J.; Fincannon, James

2017-01-01

This paper presents the preliminary results of a recent National Aeronautics and Space Administration (NASA) study funded under the Advanced Exploration Systems (AES) Modular Power Systems (AMPS) project. This study evaluated multiple surface locations on both the Moon and Mars, with the goal of establishing a common approach towards technology development and system design for surface power systems that use Regenerative Fuel Cell (RFC) energy storage methods. One RFC design may not be applicable to all surface locations; however, AMPS seeks to find a unified architecture, or series of architectures, that leverages a single development approach to answer the technology need for RFC systems. Early system trades were performed to select the most effective fuel cell and electrolyzer architectures based on current state-of-the-art technology, whereas later trades will establish a detailed system design to enable a near-term ground (non-flight) demonstration. This paper focuses on the initial trade studies, presents the selected fuel cell and electrolyzer architectures for follow-on system design studies, and suggests areas for further technology investment.

Stirling convertor performance mapping test results

NASA Astrophysics Data System (ADS)

Qiu, Songgang; Peterson, Allen A.; White, Maurice A.; Faultersack, Franklyn; Redinger, Darin L.; Petersen, Stephen L.

2002-01-01

The Department of Energy (DOE) has selected Free-Piston Stirling Convertors as a technology for future advanced radioisotope space power systems. In August 2000, DOE awarded competitive Phase I, Stirling Radioisotope Generator (SRG) power system integration contracts to three major aerospace contractors, resulting in SRG conceptual designs in February 2001. All three contractors based their designs on the Technology Demonstration Convertor (TDC) developed by Stirling Technology Company (STC) for DOE. The contract award to a single system integration contractor for Phases II and III of the SRG program is anticipated in late 2001. The first potential SRG mission is targeted for a Mars rover. Recent TDC performance data are provided in this paper, together with predictions from Stirling simulation models. .

Sandia technology engineering and science accomplishments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-01

Sandia is a DOE multiprogram engineering and science laboratory with major facilities at Albuquerque, New Mexico, and Livermore, California, and a test range near Tonapah, Nevada. We have major research and development responsibilities for nuclear weapons, arms control, energy, the environment, economic competitiveness, and other areas of importance to the needs of the nation. Our principal mission is to support national defense policies by ensuring that the nuclear weapon stockpile meets the highest standards of safety, reliability, security, use control, and military performance. Selected unclassified technical activities and accomplishments are reported here. Topics include advanced manufacturing technologies, intelligent machines, computationalmore » simulation, sensors and instrumentation, information management, energy and environment, and weapons technology.« less

Research and technology, 1990

NASA Technical Reports Server (NTRS)

1990-01-01

Selected research and technology activities at Ames Research Center, including the Moffett Field site and the Dryden Flight Research Facility, are summarized. These accomplishments exemplify the Center's varied and highly productive research efforts for 1990. The activities addressed are under the directories of: (1) aerospace systems which contains aircraft technology, full-scale aerodynamics research, information sciences, aerospace human factors research, and flight systems and simulation research divisions; (2) Dryden flight research facility which contains research engineering division; (3) aerophysics which contains aerodynamics, fluid dynamics, and thermosciences divisions; and (4) space research which contains advanced life support, space projects, earth system science, life science, and space science divisions, and search for extraterrestrial intelligence and space life sciences payloads offices.

Equivalent Mass versus Life Cycle Cost for Life Support Technology Selection

NASA Technical Reports Server (NTRS)

Jones, Harry

2003-01-01

The decision to develop a particular life support technology or to select it for flight usually depends on the cost to develop and fly it. Other criteria such as performance, safety, reliability, crew time, and technical and schedule risk are considered, but cost is always an important factor. Because launch cost would account for much of the cost of a future planetary mission, and because launch cost is directly proportional to the mass launched, equivalent mass has been used instead of cost to select advanced life support technology. The equivalent mass of a life support system includes the estimated mass of the hardware and of the spacecraft pressurized volume, power supply, and cooling system that the hardware requires. The equivalent mass of a system is defined as the total payload launch mass needed to provide and support the system. An extension of equivalent mass, Equivalent System Mass (ESM), has been established for use in the Advanced Life Support project. ESM adds a mass-equivalent of crew time and possibly other cost factors to equivalent mass. Traditional equivalent mass is strictly based on flown mass and reflects only the launch cost. ESM includes other important cost factors, but it complicates the simple flown mass definition of equivalent mass by adding a non-physical mass penalty for crew time that may exceed the actual flown mass. Equivalent mass is used only in life support analysis. Life Cycle Cost (LCC) is much more commonly used. LCC includes DDT&E, launch, and operations costs. For Earth orbit rather than planetary missions, the launch cost is less than the cost of Design, Development, Test, and Evaluation (DDTBE). LCC is a more inclusive cost estimator than equivalent mass. The relative costs of development, launch, and operations vary depending on the mission destination and duration. Since DDTBE or operations may cost more than launch, LCC gives a more accurate relative cost ranking than equivalent mass. To select the lowest cost technology for a particular application we should use LCC rather than equivalent mass.

Environmental and economic comparisons of the satellite power system and six alternative energy technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitfield, R.G.; Habegger, L.J.; Levine, E.P.

1981-04-01

The objective of the comparative assessment is to provide an initial, traceable and consistent comparison of the SPS and selected current, near-term, and advanced energy technologies. Terrestrial alternatives were selected, and their cost, performance, and environmental and societal attributes were specified for use in the comparison with the SPS in the post-2000 era. The framework for comparisons was established. The SPS was compared with alternative systems in terms of key issues such as life-cycle cost and environmental impacts. The results of the assessments were assembled and integrated into a consistent comparative assessment. Environmental and economic effects are evaluated, which weremore » subdivided into the following issue areas: human health and safety, environmental welfare, resources (land, materials, energy, water, labor), macroeconomics, socioeconomics, and institutional. These evaluations were based on technology characterization data and alternative futures scenarios, which were developed as part of CDEP by supporting studies. The technologies and the scenarios are described. An additional major issue area concerned the cost and performance of the SPS and the alternative technologies: results in this area provided part of the basis of the macroeconomic analyses. 159 references.« less

Changing the Landscape of Civil Aviation

NASA Technical Reports Server (NTRS)

Russo, Carol J.

1997-01-01

NASA is undertaking several bold new initiatives to develop revolutionary technologies for civil aviation. These technologies span the civil aviation fleet from general aviation to large subsonic and supersonic aircraft and promise to bring a new era of new aircraft, lower operation costs, faster more direct flight capabilities, more environmentally friendly aircraft, and safer airline operations. These initiatives have specific quantified goals that require technologies well beyond those currently being developed creating a bold new vision for aeronautics. Revolutionary propulsion systems are enabling for these advancements. This paper gives an overview of the new national aeronautics goals and explores for a selected subset of goals some of the revolutionary technologies will be required to meet some of these goals. The focus of the paper is on the pivotal role propulsion and icing technologies will play in changing the landscape of civil aviation.

Endoscopic and keyhole endoscope-assisted neurosurgical approaches: a qualitative survey on technical challenges and technological solutions.

PubMed

Marcus, Hani J; Cundy, Thomas P; Hughes-Hallett, Archie; Yang, Guang-Zhong; Darzi, Ara; Nandi, Dipankar

2014-10-01

The literature reflects a resurgence of interest in endoscopic and keyhole endoscope-assisted neurosurgical approaches as alternatives to conventional microsurgical approaches in carefully selected cases. The aim of this study was to assess the technical challenges of neuroendoscopy, and the scope for technological innovations to overcome these barriers. All full members of the Society of British Neurosurgeons (SBNS) were electronically invited to participate in an online survey. The open-ended structured survey asked three questions; firstly, whether the surgeon presently utilises or has experience with endoscopic or endoscope-assisted approaches; secondly, what they consider to be the major technical barriers to adopting such approaches; and thirdly, what technological advances they foresee improving safety and efficacy in the field. Responses were subjected to a qualitative research method of multi-rater emergent theme analysis. Three clear themes emerged: 1) surgical approach and better integration with image-guidance systems (20%), 2) intra-operative visualisation and improvements in neuroendoscopy (49%), and 3) surgical manipulation and improvements in instruments (74%). The analysis of responses to our open-ended survey revealed that although opinion was varied three major themes could be identified. Emerging technological advances such as augmented reality, high-definition stereo-endoscopy, and robotic joint-wristed instruments may help overcome the technical difficulties associated with neuroendoscopic approaches. Results of this qualitative survey provide consensus amongst the technology end-user community such that unambiguous goals and priorities may be defined. Systems integrating these advances could improve the safety and efficacy of endoscopic and endoscope-assisted neurosurgical approaches.

Pathfinding the Flight Advanced Stirling Convertor Design with the ASC-E3

NASA Technical Reports Server (NTRS)

Wong, Wayne A.; Wilson, Kyle; Smith, Eddie; Collins, Josh

2012-01-01

The Advanced Stirling Convertor (ASC) was initially developed by Sunpower, Inc. under contract to NASA Glenn Research Center (GRC) as a technology development project. The ASC technology fulfills NASA's need for high efficiency power convertors for future Radioisotope Power Systems (RPS). Early successful technology demonstrations between 2003 to 2005 eventually led to the expansion of the project including the decision in 2006 to use the ASC technology on the Advanced Stirling Radioisotope Generator (ASRG). Sunpower has delivered 22 ASC convertors of progressively mature designs to date to GRC. Currently, Sunpower with support from GRC, Lockheed Martin Space System Company (LMSSC), and the Department of Energy (DOE) is developing the flight ASC-F in parallel with the ASC-E3 pathfinders. Sunpower will deliver four pairs of ASC-E3 convertors to GRC which will be used for extended operation reliability assessment, independent validation and verification testing, system interaction tests, and to support LMSSC controller verification. The ASC-E3 and -F convertors are being built to the same design and processing documentation and the same product specification. The initial two pairs of ASC-E3 are built before the flight units and will validate design and processing changes prior to implementation on the ASC-F flight convertors. This paper provides a summary on development of the ASC technology and the status of the ASC-E3 build and how they serve the vital pathfinder role ahead of the flight build for ASRG. The ASRG is part of two of the three candidate missions being considered for selection for the Discovery 12 mission.

The application of advanced oxidation technologies to the treatment of effluents from the pulp and paper industry: a review.

PubMed

Hermosilla, Daphne; Merayo, Noemí; Gascó, Antonio; Blanco, Ángeles

2015-01-01

The paper industry is adopting zero liquid effluent technologies to reduce freshwater use and meet environmental regulations, which implies closure of water circuits and the progressive accumulation of pollutants that must be removed before water reuse and final wastewater discharge. The traditional water treatment technologies that are used in paper mills (such as dissolved air flotation or biological treatment) are not able to remove recalcitrant contaminants. Therefore, advanced water treatment technologies, such as advanced oxidation processes (AOPs), are being included in industrial wastewater treatment chains aiming to either improve water biodegradability or its final quality. A comprehensive review of the current state of the art regarding the use of AOPs for the treatment of the organic load of effluents from the paper industry is herein addressed considering mature and emerging treatments for a sustainable water use in this sector. Wastewater composition, which is highly dependent on the raw materials being used in the mills, the selected AOP itself, and its combination with other technologies, will determine the viability of the treatment. In general, all AOPs have been reported to achieve good organic removal efficiencies (COD removal >40%, and about an extra 20% if AOPs are combined with biological stages). Particularly, ozonation has been the most extensively reported and successfully implemented AOP at an industrial scale for effluent treatment or reuse within pulp and paper mills, although Fenton processes (photo-Fenton particularly) have actually addressed better oxidative results (COD removal ≈ 65-75%) at a lab scale, but still need further development at a large scale.

Endoscopic and Keyhole Endoscope-assisted Neurosurgical Approaches: A Qualitative Survey on Technical Challenges and Technological Solutions

PubMed Central

Marcus, Hani J; Cundy, Thomas P; Hughes-Hallett, Archie; Yang, Guang-Zhong; Darzi, Ara; Nandi, Dipankar

2014-01-01

Introduction The literature reflects a resurgence of interest in endoscopic and keyhole endoscope-assisted neurosurgical approaches as alternatives to conventional microsurgical approaches in carefully selected cases. The aim of this study was to assess the technical challenges of neuroendoscopy, and the scope for technological innovations to overcome these barriers. Materials and Methods All full members of the Society of British Neurosurgeons (SBNS) were electronically invited to participate in an online survey. The open-ended structured survey asked three questions; firstly, whether the surgeon presently utilises or has experience with endoscopic or endoscope-assisted approaches; secondly, what they consider to be the major technical barriers to adopting such approaches; and thirdly, what technological advances they foresee improving safety and efficacy in the field. Responses were subjected to a qualitative research method of multi-rater emergent themes analysis. Results Three clear themes emerged: 1) surgical approach and better integration with image-guidance systems (20%), 2) intra-operative visualisation and improvements in neuroendoscopy (49%), and 3) surgical manipulation and improvements in instruments (74%). Discussion The analysis of responses to our open-ended survey revealed that although opinion was varied three major themes could be identified. Emerging technological advances such as augmented reality, high-definition stereo-endoscopy, and robotic joint-wristed instruments may help overcome the technical difficulties associated with neuroendoscopic approaches. Conclusions Results of this qualitative survey provide consensus amongst the technology end-user community such that unambiguous goals and priorities may be defined. Systems integrating these advances could improve the safety and efficacy of endoscopic and endoscope-assisted neurosurgical approaches. PMID:24533591

Correlation study between vibrational environmental and failure rates of civil helicopter components

NASA Technical Reports Server (NTRS)

Alaniz, O.

1979-01-01

An investigation of two selected helicopter types, namely, the Models 206A/B and 212, is reported. An analysis of the available vibration and reliability data for these two helicopter types resulted in the selection of ten components located in five different areas of the helicopter and consisting primarily of instruments, electrical components, and other noncritical flight hardware. The potential for advanced technology in suppressing vibration in helicopters was assessed. The are still several unknowns concerning both the vibration environment and the reliability of helicopter noncritical flight components. Vibration data for the selected components were either insufficient or inappropriate. The maintenance data examined for the selected components were inappropriate due to variations in failure mode identification, inconsistent reporting, or inaccurate informaton.

Current advancement in radiation therapy for uterine cervical cancer.

PubMed

Nakano, Takashi; Ohno, Tatsuya; Ishikawa, Hitoshi; Suzuki, Yoshiyuki; Takahashi, Takeo

2010-01-01

Radiation therapy is one of the effective curative treatments for uterine cervical cancer. However poor clinical results for the advanced stages require further improvement of the treatment. Intensive studies on basic and clinical research have been made to improve local control, primarily important for long term survival in radiation therapy. Regarding current advancement in radiation therapy for uterine cervical cancer, the following three major subjects are pointed out; technological development to improve dose distribution by image guided radiation therapy technology, the concomitant anticancer chemotherapy with combination of radiation therapy, and radiation biological assessment of the radiation resistance of tumors. The biological factors overviewed in this article include hypoxia relating factors of HIF-1alpha, SOD, cell cycle parameters of pMI, proliferation factors of Ki67, EGFR, cerbB2, COX-2, cycle regulation proteins p53, p21, apoptosis regulation proteins Bcl2 and Bax and so on. Especially, the variety of these radiation biological factors is important for the selection of an effective treatment method for each patient to maximize the treatment benefit.

Advanced composites in Japan

NASA Technical Reports Server (NTRS)

Diefendorf, R. Judd; Hillig, William G.; Grisaffe, Salvatore J.; Pipes, R. Byron; Perepezko, John H.; Sheehan, James E.

1994-01-01

The JTEC Panel on Advanced Composites surveyed the status and future directions of Japanese high-performance ceramic and carbon fibers and their composites in metal, intermetallic, ceramic, and carbon matrices. Because of a strong carbon and fiber industry, Japan is the leader in carbon fiber technology. Japan has initiated an oxidation-resistant carbon/carbon composite program. With its outstanding technical base in carbon technology, Japan should be able to match present technology in the U.S. and introduce lower-cost manufacturing methods. However, the panel did not see any innovative approaches to oxidation protection. Ceramic and especially intermetallic matrix composites were not yet receiving much attention at the time of the panel's visit. There was a high level of monolithic ceramic research and development activity. High temperature monolithic intermetallic research was just starting, but notable products in titanium aluminides had already appeared. Matrixless ceramic composites was one novel approach noted. Technologies for high temperature composites fabrication existed, but large numbers of panels or parts had not been produced. The Japanese have selected aerospace as an important future industry. Because materials are an enabling technology for a strong aerospace industry, Japan initiated an ambitious long-term program to develop high temperature composites. Although just starting, its progress should be closely monitored in the U.S.

Laser Science & Technology Program Annual Report - 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, H-L

2001-03-20

The Laser Science and Technology (LS&T) Program Annual Report 2001 provides documentation of the achievements of the LLNL LS&T Program during the April 2001 to March 2002 period using three formats: (1) an Overview that is a narrative summary of important results for the year; (2) brief summaries of research and development activity highlights within the four Program elements: Advanced Lasers and Components (AL&C), Laser Optics and Materials (LO&M), Short Pulse Laser Applications and Technologies (SPLAT), and High-Energy Laser System and Tests (HELST); and (3) a compilation of selected articles and technical reports published in reputable scientific or technology journalsmore » in this period. All three elements (Annual Overview, Activity Highlights, and Technical Reports) are also on the Web: http://laser.llnl.gov/lasers/pubs/icfq.html. The underlying mission for the LS&T Program is to develop advanced lasers, optics, and materials technologies and applications to solve problems and create new capabilities of importance to the Laboratory and the nation. This mission statement has been our guide for defining work appropriate for our Program. A major new focus of LS&T beginning this past year has been the development of high peak power short-pulse capability for the National Ignition Facility (NIF). LS&T is committed to this activity.« less

Stud Walls With Continuous Exterior Insulation for Factory Built Housing: New York, New York (Fact Sheet), NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The Advanced Envelope Research effort will provide factory homebuilders with high performance, cost-effective alternative envelope designs. In the near term, these technologies will play a central role in meeting stringent energy code requirements. For manufactured homes, the thermal requirements, last updated by statute in 1994, will move up to the more rigorous IECC 2012 levels in 2013, the requirements of which are consistent with site built and modular housing. This places added urgency on identifying envelope technologies that the industry can implement in the short timeframe. The primary goal of this research is to develop wall designs that meet themore » thermal requirements based on 2012 IECC standards. Given the affordable nature of manufactured homes, impact on first cost is a major consideration in developing the new envelope technologies. This work is part of a four-phase, multi-year effort. Phase 1 identified seven envelope technologies and provided a preliminary assessment of three selected methods for building high performance wall systems. Phase 2 focused on the development of viable product designs, manufacturing strategies, addressing code and structural issues, and cost analysis of the three selected options. An industry advisory committee helped critique and select the most viable solution to move further in the research - stud walls with continuous exterior insulation. Phase 3, the subject of the current report, focused on the design development of the selected wall concept and explored variations on the use of exterior foam insulation. The scope also included material selection, manufacturing and cost analysis, and prototyping and testing.« less

Length of stay following percutaneous coronary intervention: An expert consensus document update from the society for cardiovascular angiography and interventions.

PubMed

Seto, Arnold H; Shroff, Adhir; Abu-Fadel, Mazen; Blankenship, James C; Boudoulas, Konstantinos Dean; Cigarroa, Joaquin E; Dehmer, Gregory J; Feldman, Dmitriy N; Kolansky, Daniel M; Lata, Kusum; Swaminathan, Rajesh V; Rao, Sunil V

2018-04-24

Since the publication of the 2009 SCAI Expert Consensus Document on Length of Stay Following percutaneous coronary intervention (PCI), advances in vascular access techniques, stent technology, and antiplatelet pharmacology have facilitated changes in discharge patterns following PCI. Additional clinical studies have demonstrated the safety of early and same day discharge in selected patients with uncomplicated PCI, while reimbursement policies have discouraged unnecessary hospitalization. This consensus update: (1) clarifies clinical and reimbursement definitions of discharge strategies, (2) reviews the technological advances and literature supporting reduced hospitalization duration and risk assessment, and (3) describes changes to the consensus recommendations on length of stay following PCI (Supporting Information Table S1). These recommendations are intended to support reasonable clinical decision making regarding postprocedure length of stay for a broad spectrum of patients undergoing PCI, rather than prescribing a specific period of observation for individual patients. © 2018 Wiley Periodicals, Inc.

Potential crashworthiness benefits to general aviation from Indianapolis Motor Speedway technology.

PubMed

Jennings, R T; Mohler, S R

1988-01-01

General aviation crashworthiness can potentially benefit from certain advances being accomplished by the automobile industry. Progressive improvements in crash protection technology, as documented by a dramatic reduction in crash injuries and fatalities at the Indianapolis Motor Speedway, reflect improved crashworthiness. The speeds of survivable general aviation aircraft impacts are in the range of the Indianapolis Motor Speedway crashes (200-220 mph). This paper relates the declining crash death rates at Indy by decade versus the increase in speeds. The continuous rise in speeds has prompted the development of new crashworthy designs and driver protection equipment. Crashworthiness improvements include crushable surrounding structures, high-grade restraint systems, protective head gear, fire resistant clothing, break-away structural components, and a "protective cocoon" concept. Adaptation of selected advances in crashworthiness design and operations accomplished at the Indianapolis Motor Speedway to the next generation of general aviation aircraft should provide significant dividends in survival of air crashes.

Moon Express Media Event

NASA Image and Video Library

2014-11-03

Rob Mueller, NASA senior technologist in the Surface Systems Office in Kennedy Space Center's Engineering and Technology Directorate, demonstrates the Regolith Advanced Surface System Operations Robot, or RASSOR, during a media event at Kennedy's automated landing and hazard avoidance technology, or ALHAT, hazard field at the north end of the Shuttle Landing Facility. The event was held to announce Moon Express Inc., of Moffett Field, California is selected to utilize Kennedy facilities for NASA's Lunar Cargo Transportation and Landing by Soft Touchdown, or Lunar CATALYST, initiative. Moon Express is developing a lander with capabilities that will enable delivery of payloads to the surface of the moon, as well as new science and exploration missions of interest to NASA and scientific and academic communities. Moon Express will base its activities at Kennedy and utilize the Morpheus ALHAT field and a hangar nearby for CATALYST testing. The Advanced Exploration Systems Division of NASA's Human Exploration and Operations Mission Directorate manages Lunar CATALYST.

Left Ventricular Assist Devices: The Adolescence of a Disruptive Technology.

PubMed

Pinney, Sean P

2015-10-01

Clinical outcomes for patients with advanced heart failure receiving left ventricular assist devices are driven by appropriate patient selection, refined surgical technique, and coordinated medical care. Perhaps even more important is innovative pump design. The introduction and widespread adoption of continuous-flow ventricular assist devices has led to a paradigm shift within the field of mechanical circulatory support, making the promise of lifetime device therapy closer to reality. The disruption caused by this new technology, on the one hand, produced meaningful improvements in patient survival and quality of life, but also introduced new clinical challenges, such as bleeding, pump thrombosis, and acquired valvular heart disease. Further evolution within this field will require financial investment to sustain innovation leading to a fully implantable, durable, and cost-effective pump for a larger segment of patients with advanced heart failure. Copyright © 2015 Elsevier Inc. All rights reserved.

New and Advanced Picosecond Lasers for Tattoo Removal.

PubMed

Adatto, Maurice A; Amir, Ruthie; Bhawalkar, Jayant; Sierra, Rafael; Bankowski, Richard; Rozen, Doran; Dierickx, Christine; Lapidoth, Moshe

2017-01-01

Early methods of tattoo removal ultimately resulted in unacceptable cosmetic outcomes. While the introduction of laser technology was an improvement over the existing chemical, mechanical, and surgical procedures, the use of nonselective tattoo removal with carbon dioxide and argon lasers led to scarring. Q-switched lasers with nanosecond (10-9) pulse domains were considered to have revolutionized tattoo treatment, by selectively heating the tattoo particles, while reducing the adverse sequelae to adjacent normal skin. Theoretical considerations of restricting pulse duration, to heat tattoo particles to higher temperatures, proposed the use of sub-nanosecond pulses to target particles with thermal relaxation times lower than the nanosecond pulses in Q-switched lasers. Initial studies demonstrated that picosecond (10-12) pulses were more effective than nanosecond pulses in clearing black tattoos. Advances in picosecond technology led to the development of commercially available lasers, incorporating several different wavelengths, to further refine pigment targeting. © 2017 S. Karger AG, Basel.

Fabrication technologies and sensing applications of graphene-based composite films: Advances and challenges.

PubMed

Yu, Xiaoqing; Zhang, Wensi; Zhang, Panpan; Su, Zhiqiang

2017-03-15

Graphene (G)-based composite materials have been widely explored for the sensing applications ascribing to their atom-thick two-dimensional conjugated structures, high conductivity, large specific surface areas and controlled modification. With the enormous advantages of film structure, G-based composite films (GCFs), prepared by combining G with different functional nanomaterials (noble metals, metal compounds, carbon materials, polymer materials, etc.), show unique optical, mechanical, electrical, chemical, and catalytic properties. Therefore, great quantities of sensors with high sensitivity, selectivity, and stability have been created in recent years. In this review, we focus on the recent advances in the fabrication technologies of GCFs and their specific sensing applications. In addition, the relationship between the properties of GCFs and sensing performance is concentrated on. Finally, the personal perspectives and key challenges of GCFs are mentioned in the hope to shed a light on their potential future research directions. Copyright © 2016 Elsevier B.V. All rights reserved.

Mission applications for advanced photovoltaic solar arrays

NASA Technical Reports Server (NTRS)

Stella, Paul M.; West, John L.; Chave, Robert G.; Mcgee, David P.; Yen, Albert S.

1990-01-01

The suitability of the Advanced Photovoltaic Solar Array (APSA) for future space missions was examined by considering the impact on the spacecraft system in general. The lightweight flexible blanket array system was compared to rigid arrays and a radio-isotope thermoelectric generator (RTG) static power source for a wide range of assumed future earth orbiting and interplanetary mission applications. The study approach was to establish assessment criteria and a rating scheme, identify a reference mission set, perform the power system assessment for each mission, and develop conclusions and recommendations to guide future APSA technology development. The authors discuss the three selected power sources, the assessment criteria and rating definitions, and the reference missions. They present the assessment results in a convenient tabular format. It is concluded that the three power sources examined, APSA, conventional solar arrays, and RTGs, can be considered to complement each other. Each power technology has its own range of preferred applications.

Avionics Architectures for Exploration: Building a Better Approach for (Human) Spaceflight Avionics

NASA Technical Reports Server (NTRS)

Goforth, Montgomery B.; Ratliff, James E.; Hames, Kevin L.; Vitalpur, Sharada V.

2014-01-01

The field of Avionics is advancing far more rapidly in terrestrial applications than in space flight applications. Spaceflight Avionics are not keeping pace with expectations set by terrestrial experience, nor are they keeping pace with the need for increasingly complex automation and crew interfaces as we move beyond Low Earth Orbit. NASA must take advantage of the strides being made by both space-related and terrestrial industries to drive our development and sustaining costs down. This paper describes ongoing efforts by the Avionics Architectures for Exploration (AAE) project chartered by NASA's Advanced Exploration Systems (AES) Program to evaluate new avionic architectures and technologies, provide objective comparisons of them, and mature selected technologies for flight and for use by other AES projects. Results from the AAE project's FY13 efforts are discussed, along with the status of FY14 efforts and future plans.

Challenges faced in long term ventricular assist device support.

PubMed

Ikegami, Hirohisa; Kurlansky, Paul; Takeda, Koji; Naka, Yoshifumi

2016-08-01

The development of ventricular assist device (VAD) has been one of the revolutionary advancements in end-stage heart failure management. Although the device has developed and improved significantly over the last few decades, we still face multiple challenges. This review will discuss quality of life, survival, and clinically encountered complications in patients with VAD support. The literature was extensively reviewed for studies describing the above topic area. We describe the impact of major challenges faced in VAD support and discuss their future and expectations. Expert commentary: The technological advancement of VADs has contributed to major improvement of overall survival, enhancement of quality of life and decrease of incidence of complications. It is expected that technologies will continue to evolve. At the same time, the indications for and timing of device implantation, and selection of device type are continuously important in clinical practice setting.

Study of metallic structural design concepts for an arrow wing supersonic cruise configuration

NASA Technical Reports Server (NTRS)

Turner, M. J.; Grande, D. L.

1977-01-01

A structural design study was made, to assess the relative merits of various metallic structural concepts and materials for an advanced supersonic aircraft cruising at Mach 2.7. Preliminary studies were made to ensure compliance of the configuration with general design criteria, integrate the propulsion system with the airframe, select structural concepts and materials, and define an efficient structural arrangement. An advanced computerized structural design system was used, in conjunction with a relatively large, complex finite element model, for detailed analysis and sizing of structural members to satisfy strength and flutter criteria. A baseline aircraft design was developed for assessment of current technology. Criteria, analysis methods, and results are presented. The effect on design methods of using the computerized structural design system was appraised, and recommendations are presented concerning further development of design tools, development of materials and structural concepts, and research on basic technology.

Aquila field: Advanced contracting strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-04-01

Aquila oil field, in 2,800 ft of water, is in the middle of the Otranto Channel in the Mediterranean Sea, approximately 28 miles offshore southern Italy, and is subject to difficult sea and weather conditions. The many difficulties, caused mainly by water depth, requires the use of advanced technology that can be obtained only through the direct association with contractor companies. This solution safeguards the technological reliability and allows for maximum control of time and cost. The selection of a floating production, storage, and offloading (FPSO) system resulted from a feasibility study that indicated this solution was the only methodmore » that would provide economical exploitation of the Aquila field. The system includes flowlines and control lines. The ship, FPSO Agip Firenze, has been specially redesigned to manage the field development. Agip will provide the subsea production system, the Christmas tree, control system, and artificial lift.« less

Visualising reacting single atoms under controlled conditions: Advances in atomic resolution in situ Environmental (Scanning) Transmission Electron Microscopy (E(S)TEM)

NASA Astrophysics Data System (ADS)

Boyes, Edward D.; Gai, Pratibha L.

2014-02-01

Advances in atomic resolution Environmental (Scanning) Transmission Electron Microscopy (E(S)TEM) for probing gas-solid catalyst reactions in situ at the atomic level under controlled reaction conditions of gas environment and temperature are described. The recent development of the ESTEM extends the capability of the ETEM by providing the direct visualisation of single atoms and the atomic structure of selected solid state heterogeneous catalysts in their working states in real-time. Atomic resolution E(S)TEM provides a deeper understanding of the dynamic atomic processes at the surface of solids and their mechanisms of operation. The benefits of atomic resolution-E(S)TEM to science and technology include new knowledge leading to improved technological processes with substantial economic benefits, improved healthcare, reductions in energy needs and the management of environmental waste generation. xml:lang="fr"

Advanced display object selection methods for enhancing user-computer productivity

NASA Technical Reports Server (NTRS)

Osga, Glenn A.

1993-01-01

The User-Interface Technology Branch at NCCOSC RDT&E Division has been conducting a series of studies to address the suitability of commercial off-the-shelf (COTS) graphic user-interface (GUI) methods for efficiency and performance in critical naval combat systems. This paper presents an advanced selection algorithm and method developed to increase user performance when making selections on tactical displays. The method has also been applied with considerable success to a variety of cursor and pointing tasks. Typical GUI's allow user selection by: (1) moving a cursor with a pointing device such as a mouse, trackball, joystick, touchscreen; and (2) placing the cursor on the object. Examples of GUI objects are the buttons, icons, folders, scroll bars, etc. used in many personal computer and workstation applications. This paper presents an improved method of selection and the theoretical basis for the significant performance gains achieved with various input devices tested. The method is applicable to all GUI styles and display sizes, and is particularly useful for selections on small screens such as notebook computers. Considering the amount of work-hours spent pointing and clicking across all styles of available graphic user-interfaces, the cost/benefit in applying this method to graphic user-interfaces is substantial, with the potential for increasing productivity across thousands of users and applications.