NASA Astrophysics Data System (ADS)
Liu, Maochang; Yang, Yang; Li, Naixu; Du, Yuanchang; Song, Dongxing; Ma, Lijing; Wang, Yi; Zheng, Yiqun; Jing, Dengwei
2017-08-01
Plasmonic Ag nanostructures have been of great interest for such applications in cancer therapy and catalysis, etc. However, the relatively week Ag-Ag interaction and spontaneous atom diffusion make it very difficult to generate concaved or branched structures in Ag nanocrystals with sizes less than 100 nm, which has been considered very favorable for plasmonic effects. Herein, by employing a cubic Pd seed and a specific reducing agent to restrict the surface diffusion of Ag atoms, Pd@Ag core-shell nanooctapod structures where Ag atoms can be selectively deposited onto the corner sites of the Pd cubes were obtained. Such selective decoration enables us to precisely control the locations for the hot spot formation during light irradiation. We find that the branched nanooctapod structure shows strong absorption in the visible-light region and generates intense hot spots around the octapod arms of Ag. As such, the photothermal conversion efficiency could be significantly improved by more than 50% with a colloid solution containing only ppm-level nanooctapods compared with pure water. The reported nanostructure is expected to find extensive applications due to its controlled formation of light-induced hot spots at certain points on the crystal surface.
Pre-cometary ice composition from hot core chemistry.
Tornow, Carmen; Kührt, Ekkehard; Motschmann, Uwe
2005-10-01
Pre-cometary ice located around star-forming regions contains molecules that are pre-biotic compounds or pre-biotic precursors. Molecular line surveys of hot cores provide information on the composition of the ice since it sublimates near these sites. We have combined a hydrostatic hot core model with a complex network of chemical reactions to calculate the time-dependent abundances of molecules, ions, and radicals. The model considers the interaction between the ice and gas phase. It is applied to the Orion hot core where high-mass star formation occurs, and to the solar-mass binary protostar system IRAS 16293-2422. Our calculations show that at the end of the hot core phase both star-forming sites produce the same prebiotic CN-bearing molecules. However, in the Orion hot core these molecules are formed in larger abundances. A comparison of the calculated values with the abundances derived from the observed line data requires a chemically unprocessed molecular cloud as the initial state of hot core evolution. Thus, it appears that these objects are formed at a much younger cloud stage than previously thought. This implies that the ice phase of the young clouds does not contain CN-bearing molecules in large abundances before the hot core has been formed. The pre-biotic molecules synthesized in hot cores cause a chemical enrichment in the gas phase and in the pre-cometary ice. This enrichment is thought to be an important extraterrestrial aspect of the formation of life on Earth and elsewhere.
NASA Astrophysics Data System (ADS)
Bayet, E.; Yates, J.; Viti, S.
2011-02-01
We present a theoretical study of CS line profiles in archetypal hot cores. We provide estimates of line fluxes from the CS(1-0) to the CS(15-14) transitions and present the temporal variation of these fluxes. We find that (1) the CS(1-0) transition is a better tracer of the Envelope of the hot core whereas the higher-J CS lines trace the ultracompact core (UCC); (2) the peak temperature of the CS transitions is a good indicator of the temperature inside the hot core; (3) in the Envelope, the older the hot core the stronger the self-absorption of CS; (4) the fractional abundance of CS is highest in the innermost parts of the UCC, confirming the CS molecule as one of the best tracers of very dense gas.
The Chandra Strong Lens Sample: Revealing Baryonic Physics In Strong Lensing Selected Clusters
NASA Astrophysics Data System (ADS)
Bayliss, Matthew
2017-08-01
We propose for Chandra imaging of the hot intra-cluster gas in a unique new sample of 29 galaxy clusters selected purely on their strong gravitational lensing signatures. This will be the first program targeting a purely strong lensing selected cluster sample, enabling new comparisons between the ICM properties and scaling relations of strong lensing and mass/ICM selected cluster samples. Chandra imaging, combined with high precision strong lens models, ensures powerful constraints on the distribution and state of matter in the cluster cores. This represents a novel angle from which we can address the role played by baryonic physics |*| the infamous |*|gastrophysics|*| in shaping the cores of massive clusters, and opens up an exciting new galaxy cluster discovery space with Chandra.
The Chandra Strong Lens Sample: Revealing Baryonic Physics In Strong Lensing Selected Clusters
NASA Astrophysics Data System (ADS)
Bayliss, Matthew
2017-09-01
We propose for Chandra imaging of the hot intra-cluster gas in a unique new sample of 29 galaxy clusters selected purely on their strong gravitational lensing signatures. This will be the first program targeting a purely strong lensing selected cluster sample, enabling new comparisons between the ICM properties and scaling relations of strong lensing and mass/ICM selected cluster samples. Chandra imaging, combined with high precision strong lens models, ensures powerful constraints on the distribution and state of matter in the cluster cores. This represents a novel angle from which we can address the role played by baryonic physics -- the infamous ``gastrophysics''-- in shaping the cores of massive clusters, and opens up an exciting new galaxy cluster discovery space with Chandra.
A new look at sulphur chemistry in hot cores and corinos
NASA Astrophysics Data System (ADS)
Vidal, Thomas H. G.; Wakelam, Valentine
2018-03-01
Sulphur-bearing species are often used to probe the evolution of hot cores because their abundances are particularly sensitive to physical and chemical variations. However, the chemistry of sulphur is not well understood in these regions, notably because observations of several hot cores have displayed a large variety of sulphur compositions, and because the reservoir of sulphur in dense clouds, in which hot cores form, is still poorly constrained. In order to help disentangle its complexity, we present a fresh comprehensive review of sulphur chemistry in hot cores along with a study of sulphur's sensibility to temperature and pre-collapse chemical composition. In parallel, we analyse the discrepencies that result from the use of two different types of models (static and dynamic) in order to highlight the sensitivity to the choice of model to be used in astrochemical studies. Our results show that the pre-collapse chemical composition is a critical parameter for sulphur chemistry in hot cores and that it could explain the different sulphur compositions observed. We also report that differences in abundances for a given species between the static and dynamic models can reach six orders of magnitude in the hot core, which reveals the key role of the choice of model in astrochemical studies.
SOFIA/EXES High Spectral Resolution Observations of the Orion Hot Core
NASA Astrophysics Data System (ADS)
Rangwala, Naseem; Colgan, Sean; Le Gal, Romane; Acharya, Kinsuk; Huang, Xinchuan; Herbst, Eric; Lee, Timothy J.; Richter, Matthew J.; Boogert, Adwin
2018-01-01
The Orion hot core has one of the richest molecular chemistries observed in the ISM. In the MIR, the Orion hot core composition is best probed by the closest, compact, bright background continuum source in this region, IRc2. We present high-spectral resolution observations from 12.96 - 13.33 μm towards Orion IRc2 using the mid-infrared spectrograph, EXES, on SOFIA, to probe the physical and chemical conditions of the Orion hot core. All ten of the rovibrational C2H2 transitions expected in our spectral coverage, are detected with high S/N, yielding continuous coverage of the R-branch lines from J=9-8 to J=18-17, including both ortho and para species. Eight of these rovibrational transitions are newly reported detections. These data show distinct ortho and para ladders towards the Orion hot core for the first time, with an ortho to para ratio (OPR) of only 0.6 - much lower than the high temperature equilibrium value of 3. A non-equilibrium OPR is a further indication of the Orion hot core being heated externally by shocks likely resulting from a well-known explosive event which occurred 500 yrs ago. The OPR conversion timescales are much longer than the 500 yr shock timescale and thus a low OPR might be a remnant from an earlier colder pre-stellar phase before the density enhancement (now the hot core) was impacted by shocks.We will also present preliminary results from an on-going SOFIA Cycle-5 impact program to use EXES to conduct an unbiased, high-S/N, continuous, molecular line survey of the Orion hot core from 12.5 - 28.3 microns. This survey is expected to be 50 times better than ISO in detecting isolated, narrow lines to (a) resolve the ro-vibrational structure of the gas phase molecules and their kinematics, (b) detect new gas phase molecules missed by ISO, and (c) provide useful constraints on the hot core chemistry and the source of Orion hot core excitation. This survey will greatly enhance the inventory of resolved line features in the MIR for hot cores, making it an invaluable reference to be used by the JWST and ALMA scientific communities.
[Hot spot mutation screening of RYR1 gene in diagnosis of congenital myopathies].
Chang, Xing-zhi; Jin, Yi-wen; Wang, Jing-min; Yuan, Yun; Xiong, Hui; Wang, Shuang; Qin, Jiong
2014-10-18
To detect hot spot mutation of RYR1 gene in 15 cases of congenital myopathy with different subtypes, and to discuss the value of RYR1 gene hot spot mutation detection in the diagnosis of the disease. Clinical data were collected in all the patients, including clinical manifestations and signs, serum creatine kinase, electromyography. Fourteen of the patients accepted the muscle biopsy. Hot spot mutation in the C-terminal of RYR1 gene (extron 96-106) had been detected in all the 15 patients. All the patients presented with motor development delay, and they could walk at the age of 1 to 3.5 years,but were always easy to fall and could not run or jump. There were no progressive deteriorations. Physical examination showed different degrees of muscle weakness and hypotonia.High arched palates were noted in 3 patients. The serum levels of creatine kinase were mildly elevated in 3 cases, and normal in 12 cases. Electromyography showed "myogenic" features in 11 patients, being normal in the other 4 patients. Muscle biopsy pathologic diagnosis was the central core disease in 3 patients, the central nuclei in 2 patients, the congenital fiber type disproportion in 2 patients, the nameline myopathy in 3 patient, the multiminicore disease in 1 patient, and nonspecific minimal changes in the other 3 patients; one patient was diagnosed with central core disease according to positive family history and gene mutation. In the family case (Patient 2) of central core disease, the c.14678G>A (p.Arg4893Gln) mutation in 102 extron of RYR1 was identified in three members of the family, which had been reported to be a pathogenic mutation. The c.14596A>G(p.Lys4866Gln) mutation in 101 extron was found in one patient with central core disease(Patient 1), and the c.14719G>A(p.Gly4907Ser) mutation in 102 extron was found in another case of the central core disease(Patient 3).The same novel mutation was verified in one of the patients' (Patient 3) asymptomatic father. Congenital myopathies in the different subtype have the similar clinical manifestations, signs, enzyme detection and electromyography changes. Muscle biopsy plays an important role in the selection of genes to be detected. Hot spot mutation in C-terminal of the RYR1 gene can only be identified in patients with central core disease, so we suggest this hot spot gene mutation screening apply to the suspicious patient with central core disease only.
THE DETECTION OF A HOT MOLECULAR CORE IN THE LARGE MAGELLANIC CLOUD WITH ALMA
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shimonishi, Takashi; Onaka, Takashi; Kawamura, Akiko
We report the first detection of a hot molecular core outside our Galaxy based on radio observations with ALMA toward a high-mass young stellar object (YSO) in a nearby low metallicity galaxy, the Large Magellanic Cloud (LMC). Molecular emission lines of CO, C{sup 17}O, HCO{sup +}, H{sup 13}CO{sup +}, H{sub 2}CO, NO, SiO, H{sub 2}CS, {sup 33}SO, {sup 32}SO{sub 2}, {sup 34}SO{sub 2}, and {sup 33}SO{sub 2} are detected from a compact region (∼0.1 pc) associated with a high-mass YSO, ST11. The temperature of molecular gas is estimated to be higher than 100 K based on rotation diagram analysis ofmore » SO{sub 2} and {sup 34}SO{sub 2} lines. The compact source size, warm gas temperature, high density, and rich molecular lines around a high-mass protostar suggest that ST11 is associated with a hot molecular core. We find that the molecular abundances of the LMC hot core are significantly different from those of Galactic hot cores. The abundances of CH{sub 3}OH, H{sub 2}CO, and HNCO are remarkably lower compared to Galactic hot cores by at least 1–3 orders of magnitude. We suggest that these abundances are characterized by the deficiency of molecules whose formation requires the hydrogenation of CO on grain surfaces. In contrast, NO shows a high abundance in ST11 despite the notably low abundance of nitrogen in the LMC. A multitude of SO{sub 2} and its isotopologue line detections in ST11 imply that SO{sub 2} can be a key molecular tracer of hot core chemistry in metal-poor environments. Furthermore, we find molecular outflows around the hot core, which is the second detection of an extragalactic protostellar outflow. In this paper, we discuss the physical and chemical characteristics of a hot molecular core in the low metallicity environment.« less
Direct Heating of a Laser-Imploded Core by Ultraintense Laser-Driven Ions
NASA Astrophysics Data System (ADS)
Kitagawa, Y.; Mori, Y.; Komeda, O.; Ishii, K.; Hanayama, R.; Fujita, K.; Okihara, S.; Sekine, T.; Satoh, N.; Kurita, T.; Takagi, M.; Watari, T.; Kawashima, T.; Kan, H.; Nishimura, Y.; Sunahara, A.; Sentoku, Y.; Nakamura, N.; Kondo, T.; Fujine, M.; Azuma, H.; Motohiro, T.; Hioki, T.; Kakeno, M.; Miura, E.; Arikawa, Y.; Nagai, T.; Abe, Y.; Ozaki, S.; Noda, A.
2015-05-01
A novel direct core heating fusion process is introduced, in which a preimploded core is predominantly heated by energetic ions driven by LFEX, an extremely energetic ultrashort pulse laser. Consequently, we have observed the D (d ,n )
Direct heating of a laser-imploded core by ultraintense laser-driven ions.
Kitagawa, Y; Mori, Y; Komeda, O; Ishii, K; Hanayama, R; Fujita, K; Okihara, S; Sekine, T; Satoh, N; Kurita, T; Takagi, M; Watari, T; Kawashima, T; Kan, H; Nishimura, Y; Sunahara, A; Sentoku, Y; Nakamura, N; Kondo, T; Fujine, M; Azuma, H; Motohiro, T; Hioki, T; Kakeno, M; Miura, E; Arikawa, Y; Nagai, T; Abe, Y; Ozaki, S; Noda, A
2015-05-15
A novel direct core heating fusion process is introduced, in which a preimploded core is predominantly heated by energetic ions driven by LFEX, an extremely energetic ultrashort pulse laser. Consequently, we have observed the D(d,n)^{3}He-reacted neutrons (DD beam-fusion neutrons) with the yield of 5×10^{8} n/4π sr. Examination of the beam-fusion neutrons verified that the ions directly collide with the core plasma. While the hot electrons heat the whole core volume, the energetic ions deposit their energies locally in the core, forming hot spots for fuel ignition. As evidenced in the spectrum, the process simultaneously excited thermal neutrons with the yield of 6×10^{7} n/4π sr, raising the local core temperature from 0.8 to 1.8 keV. A one-dimensional hydrocode STAR 1D explains the shell implosion dynamics including the beam fusion and thermal fusion initiated by fast deuterons and carbon ions. A two-dimensional collisional particle-in-cell code predicts the core heating due to resistive processes driven by hot electrons, and also the generation of fast ions, which could be an additional heating source when they reach the core. Since the core density is limited to 2 g/cm^{3} in the current experiment, neither hot electrons nor fast ions can efficiently deposit their energy and the neutron yield remains low. In future work, we will achieve the higher core density (>10 g/cm^{3}); then hot electrons could contribute more to the core heating via drag heating. Together with hot electrons, the ion contribution to fast ignition is indispensable for realizing high-gain fusion. By virtue of its core heating and ignition, the proposed scheme can potentially achieve high gain fusion.
Hot Cores in Magellanic Clouds
NASA Astrophysics Data System (ADS)
Acharyya, Kinsuk; Herbst, Eric
2018-05-01
We have studied the chemistry of molecules through complex organic molecules (COMs) in complexity in conditions resembling galactic hot molecular cores in the Large and Small Magellanic Clouds using a gas-grain network. To the best of our knowledge, there have been no previous such quantitative studies of hot core chemistry in these low metallicity, dust-poor galaxies. We utilized a physical model that consists of an initial isothermal collapse, followed by a warm-up phase to hot core conditions. Four different temperatures—10, 15, 20, and 25 K—were used for the isothermal collapse phase, considering the fact that these galaxies might have higher dust temperatures in cold regions than observed in the Milky Way. We found that for some abundant species, such as CO and water, hot core abundances are consistent with the reduced elemental abundances of the LMC and SMC. For other less abundant species, such as CH4 and HCN, the calculated abundances are larger when compared with elemental abundances, whereas for species like ammonia they are lower. Our calculations show that some COMs can also be formed in reasonable quantity for hot cores in the Magellanic Clouds when the grain temperature is lower than 25 K. Our results can be compared with recent observations of the hot cores in the high-mass young stellar object (YSO) ST11 and regions A1 and B3 of the star-forming source N113 in the LMC. Model results are in reasonable agreement with the observed abundances and upper limits.
NASA Astrophysics Data System (ADS)
Nagarajan, Satyakumar; McMillan, James P.; Burkhardt, Andrew M.; Neese, Christopher F.; De Lucia, Frank C.; Remijan, Anthony
2016-06-01
Individual spectral lines in astrophysical data are ordinarily assigned by comparison with line frequency and intensities predicted by catalogs. Here we seek to fit the spectra of specific sources within Orion KL that are first selected by ALMA's angular resolution and then by Doppler velocity class. For each molecule in this study, astrophysical reference lines are selected. Subsequent analyses of individual velocity components provide the astrophysical column density and temperature for these velocity regimes. These column densities and temperatures are then combined with results from the complete experimental spectra obtained from our laboratory spectra to model the molecule's contribution to the entire astrophysical spectrum [1]. Effects due to optical thickness and spectral overlap are included in the analyses. Examples for ethyl cyanide in the hot core and methanol in the compact ridge will be presented. [1] J. P. McMillan, S. M. Fortman, C. F. Neese, and F. C. De Lucia, "The Complete, Temperature Resolved Experi- mental Spectrum of Methanol (CH3OH) between 214.6 and 265.4 GHz," Astrophys. J., vol. 795, pp. 56(1-9), 2014.
A Survey of Large Molecules of Biological Interest toward Selected High Mass Star Forming Regions
NASA Technical Reports Server (NTRS)
Remijan, A.; Shiao, Y.-S.; Friedel, D. N.; Meier, D. S.; Snyder, L. E.
2004-01-01
We have surveyed three high mass Galactic star forming regions for interstellar methanol (CH3OH), formic acid (HCOOH), acetic acid (CH3COOH), methyl formate (HCOOCH3), methyl cyanide (CH3CN), and ethyl cyanide (CH3CH2CN) with the BIMA Array. From our observations, we have detected two new sources of interstellar HCOOH toward the hot core regions G19.61-0.23 and W75N. We have also made the first detections of CH3CH2CN and HCOOCH3 toward G19.61-0.23. The relative HCOOH/HCOOCH3 abundance ratio toward G19.61-0.23 is 0.18 which is comparable to the abundance ratios found by Liu and colleagues toward Sgr B2(N-LMH), Orion and W51(approximately 0.10). We have made the first detection of HCOOCH3 toward W75N. The relative HCOOH/HCOOCH3 abundance ratio toward W75N is 0.26 which is more than twice as large as the abundance ratios found by Liu and colleagues. Furthermore, the hot core regions around W75N show a chemical differentiation between the O and N cores similar to what is seen toward the Orion Hot Core and Compact Ridge and W3(OH) and W3(H2O). It is also apparent from our observations that the high mass star forming region G45.47+0.05 does not contain any compact hot molecular core and as a consequence its chemistry may be similar to cold dark clouds. Finally, the formation of CH3COOH appears to favor HMCs with well mixed N and O, despite the fact that CH3COOH does not contain a N atom. If proved to be true, this is an important constraint on CH3COOH formation and possibly other structurally similar biomolecules.
Process to make core-shell structured nanoparticles
Luhrs, Claudia; Phillips, Jonathan; Richard, Monique N
2014-01-07
Disclosed is a process for making a composite material that contains core-shell structured nanoparticles. The process includes providing a precursor in the form of a powder a liquid and/or a vapor of a liquid that contains a core material and a shell material, and suspending the precursor in an aerosol gas to produce an aerosol containing the precursor. In addition, the process includes providing a plasma that has a hot zone and passing the aerosol through the hot zone of the plasma. As the aerosol passes through the hot zone of the plasma, at least part of the core material and at least part of the shell material in the aerosol is vaporized. Vapor that contains the core material and the shell material that has been vaporized is removed from the hot zone of the plasma and allowed to condense into core-shell structured nanoparticles.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Juárez, Carmen; Girart, Josep M.; Zamora-Avilés, Manuel
We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s{sup −1}, converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamicmore » simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.« less
High-temperature, high-pressure bonding of nested tubular metallic components
Quinby, T.C.
A tool is described for effecting high-temperature, high-compression bonding between the confronting faces of nested, tubular, metallic components. In a typical application, the tool is used to produce tubular target assemblies for irradiation in nuclear reactors or particle accelerators. The target assembly comprising a uranum foil and an aluninum-alloy substrate. The tool is composed of graphite. It comprises a tubular restraining member in which a mechanically expandable tubular core is mounted to form an annulus. The components to be bonded are mounted in nested relation in the annulus. The expandable core is formed of individually movable, axially elongated segments whose outer faces cooperatively define a cylindrical pressing surface and whose inner faces cooperatively define two opposed, inwardly tapered, axial bores. Tapered rams extend into the bores. The loaded tool is mounted in a conventional hot-press provided with evacuation means, heaters for maintaining its interior at bonding temperature, and hydraulic cylinders for maintaining a selected inwardly directed pressure on the tapered rams. With the hot-press evacuated and the loaded tool at the desired temperature, the cylinders are actuated to apply the selected pressure to the rams. The rams in turn expand the segmented core to maintain the nested components in compression against the restraining member. These conditions are maintained until the confronting faces of the nested components are joined in a continuous, uniform bond characterized by high thermal conductivity.
High skin temperature and hypohydration impair aerobic performance.
Sawka, Michael N; Cheuvront, Samuel N; Kenefick, Robert W
2012-03-01
This paper reviews the roles of hot skin (>35°C) and body water deficits (>2% body mass; hypohydration) in impairing submaximal aerobic performance. Hot skin is associated with high skin blood flow requirements and hypohydration is associated with reduced cardiac filling, both of which act to reduce aerobic reserve. In euhydrated subjects, hot skin alone (with a modest core temperature elevation) impairs submaximal aerobic performance. Conversely, aerobic performance is sustained with core temperatures >40°C if skin temperatures are cool-warm when euhydrated. No study has demonstrated that high core temperature (∼40°C) alone, without coexisting hot skin, will impair aerobic performance. In hypohydrated subjects, aerobic performance begins to be impaired when skin temperatures exceed 27°C, and even warmer skin exacerbates the aerobic performance impairment (-1.5% for each 1°C skin temperature). We conclude that hot skin (high skin blood flow requirements from narrow skin temperature to core temperature gradients), not high core temperature, is the 'primary' factor impairing aerobic exercise performance when euhydrated and that hypohydration exacerbates this effect.
Hot flashes, core body temperature, and metabolic parameters in breast cancer survivors.
Carpenter, Janet S; Gilchrist, Janet M; Chen, Kong; Gautam, Shiva; Freedman, Robert R
2004-01-01
To examine core body temperature, energy expenditure, and respiratory quotient among breast cancer survivors experiencing hot flashes and compare these data to published studies from healthy women. In an observational study, nine breast cancer survivors with daily hot flashes who met specified criteria spent 24 hours in a temperature- and humidity-controlled whole-room indirect calorimeter (ie, metabolic room). Demographic and disease/treatment information were obtained and the following were measured: hot flashes via sternal skin conductance monitoring (sampled every second); core body temperature via an ingested radiotelemetry pill (sampled every 10 seconds); and energy expenditure and respiratory quotient via a whole-room indirect calorimeter (calculated every minute). Circadian analysis of core temperature indicated wide variability with disrupted circadian rhythm noted in all women. Core temperature began to rise 20 minutes pre-flash to 7 minutes pre-flash (0.09 degrees C increase). Increases in energy expenditure and respiratory quotient increased with each hot flash. Findings are comparable to published data from healthy women and warrant replication in larger, more diverse samples of women treated for breast cancer.
Physiological Responses and Physical Performance during Football in the Heat
Mohr, Magni; Nybo, Lars; Grantham, Justin; Racinais, Sebastien
2012-01-01
Purpose To examine the impact of hot ambient conditions on physical performance and physiological responses during football match-play. Methods Two experimental games were completed in temperate (∼21°C; CON) and hot ambient conditions (∼43°C; HOT). Physical performance was assessed by match analysis in 17 male elite players during the games and a repeated sprint test was conducted after the two game trials. Core and muscle temperature were measured and blood samples were obtained, before and after the games. Results Muscle and core temperatures were ∼1°C higher (P<0.05) in HOT (40.3±0.1 and 39.5±0.1°C, respectively) compared to CON (39.2±0.1 and 38.3±0.1°C). Average heart rate, plasma lactate concentration, body weight loss as well as post-game sprint performance were similar between the two conditions. Total game distance declined (P<0.05) by 7% and high intensity running (>14 km⋅h−1) by 26% in HOT compared to CON), but peak sprint speed was 4% higher (P<0.05) in HOT than in CON, while there were no differences in the quantity or length of sprints (>24 km⋅h−1) between CON and HOT. In HOT, success rates for passes and crosses were 8 and 9% higher (P<0.05), respectively, compared to CON. Delta increase in core temperature and absolute core temperature in HOT were correlated to total game distance in the heat (r = 0.85 and r = 0.53, respectively; P<0.05), whereas, total and high intensity distance deficit between CON and HOT were not correlated to absolute or delta changes in muscle or core temperature. Conclusion Total game distance and especially high intensity running were lower during a football game in the heat, but these changes were not directly related to the absolute or relative changes in core or muscle temperature. However, peak sprinting speed and execution of successful passes and crosses were improved in the HOT condition. PMID:22723963
Core-in-shell sorbent for hot coal gas desulfurization
Wheelock, Thomas D.; Akiti, Jr., Tetteh T.
2004-02-10
A core-in-shell sorbent is described herein. The core is reactive to the compounds of interest, and is preferably calcium-based, such as limestone for hot gas desulfurization. The shell is a porous protective layer, preferably inert, which allows the reactive core to remove the desired compounds while maintaining the desired physical characteristics to withstand the conditions of use.
Yang, Yan; Shen, Lian; Li, Juan; Shan, Wei-Guang
2017-06-01
The objective of this study was to prepare and evaluate metoprolol tartrate sustained-release pellets. Cores were prepared by hot melt extrusion and coated pellets were prepared by hot melt coating. Cores were found to exist in a single-phase state and drug in amorphous form. Plasticizers had a significant effect on torque and drug content, while release modifiers and coating level significantly affected the drug-release behavior. The mechanisms of drug release from cores and coated pellets were Fickian diffusion and diffusion-erosion. The coated pellets exhibited sustained-release properties in vitro and in vivo.
Energy efficient engine shroudless, hollow fan blade technology report
NASA Technical Reports Server (NTRS)
Michael, C. J.
1981-01-01
The Shroudless, Hollow Fan Blade Technology program was structured to support the design, fabrication, and subsequent evaluation of advanced hollow and shroudless blades for the Energy Efficient Engine fan component. Rockwell International was initially selected to produce hollow airfoil specimens employing the superplastic forming/diffusion bonding (SPF/DB) fabrication technique. Rockwell demonstrated that a titanium hollow structure could be fabricated utilizing SPF/DB manufacturing methods. However, some problems such as sharp internal cavity radii and unsatisfactory secondary bonding of the edge and root details prevented production of the required quantity of fatigue test specimens. Subsequently, TRW was selected to (1) produce hollow airfoil test specimens utilizing a laminate-core/hot isostatic press/diffusion bond approach, and (2) manufacture full-size hollow prototype fan blades utilizing the technology that evolved from the specimen fabrication effort. TRW established elements of blade design and defined laminate-core/hot isostatic press/diffusion bonding fabrication techniques to produce test specimens. This fabrication technology was utilized to produce full size hollow fan blades in which the HIP'ed parts were cambered/twisted/isothermally forged, finish machined, and delivered to Pratt & Whitney Aircraft and NASA for further evaluation.
Chemistry of the organic-rich hot core G327.3-0.6
NASA Technical Reports Server (NTRS)
Gibb, E.; Nummelin, A.; Irvine, W. M.; Whittet, D. C.; Bergman, P.; Ferris, J. P. (Principal Investigator)
2000-01-01
We present gas-phase abundances of species found in the organic-rich hot core G327.3-0.6. The data were taken with the Swedish-ESO Submillimetre Telescope (SEST). The 1-3 mm spectrum of this source is dominated by emission features of nitrile species and saturated organics, with abundances greater than those found in many other hot cores, including Sgr B2 and OMC-1. Population diagram analysis indicates that many species (CH3CN, C2H3CN, C2H5CN, CH3OH, etc.) have hot components that originate in a compact (2") region. Gas-phase chemical models cannot reproduce the high abundances of these molecules found in hot cores, and we suggest that they originate from processing and evaporation of icy grain mantle material. In addition, we report the first detection of vibrationally excited ethyl cyanide and the first detection of methyl mercaptan (CH3SH) outside the Galactic center.
High-temperature, high-pressure bonding of nested tubular metallic components
Quinby, Thomas C.
1980-01-01
This invention is a tool for effecting high-temperature, high-compression bonding between the confronting faces of nested, tubular, metallic components. In a typical application, the tool is used to produce tubular target assemblies for irradiation in nuclear reactors or particle accelerators, the target assembly comprising a uranium foil and an aluminum-alloy substrate. The tool preferably is composed throughout of graphite. It comprises a tubular restraining member in which a mechanically expandable tubular core is mounted to form an annulus with the member. The components to be bonded are mounted in nested relation in the annulus. The expandable core is formed of individually movable, axially elongated segments whose outer faces cooperatively define a cylindrical pressing surface and whose inner faces cooperatively define two opposed, inwardly tapered, axial bores. Tapered rams extend respectively into the bores. The loaded tool is mounted in a conventional hot-press provided with evacuation means, heaters for maintaining its interior at bonding temperature, and hydraulic cylinders for maintaining a selected inwardly directed pressure on the tapered rams. With the hot-press evacuated and the loaded tool at the desired temperature, the cylinders are actuated to apply the selected pressure to the rams. The rams in turn expand the segmented core to maintain the nested components in compression against the restraining member. These conditions are maintained until the confronting faces of the nested components are joined in a continuous, uniform bond characterized by high thermal conductivity.
Hot spot analysis for driving the development of hits into leads in fragment based drug discovery
Hall, David R.; Ngan, Chi Ho; Zerbe, Brandon S.; Kozakov, Dima; Vajda, Sandor
2011-01-01
Fragment based drug design (FBDD) starts with finding fragment-sized compounds that are highly ligand efficient and can serve as a core moiety for developing high affinity leads. Although the core-bound structure of a protein facilitates the construction of leads, effective design is far from straightforward. We show that protein mapping, a computational method developed to find binding hot spots and implemented as the FTMap server, provides information that complements the fragment screening results and can drive the evolution of core fragments into larger leads with a minimal loss or, in some cases, even a gain in ligand efficiency. The method places small molecular probes, the size of organic solvents, on a dense grid around the protein, and identifies the hot spots as consensus clusters formed by clusters of several probes. The hot spots are ranked based on the number of probe clusters, which predicts the binding propensity of the subsites and hence their importance for drug design. Accordingly, with a single exception the main hot spot identified by FTMap binds the core compound found by fragment screening. The most useful information is provided by the neighboring secondary hot spots, indicating the regions where the core can be extended to increase its affinity. To quantify this information, we calculate the density of probes from mapping, which describes the binding propensity at each point, and show that the change in the correlation between a ligand position and the probe density upon extending or repositioning the core moiety predicts the expected change in ligand efficiency. PMID:22145575
NASA Technical Reports Server (NTRS)
Wang, Ten-See; Foote, John; Litchford, Ron
2006-01-01
The objective of this effort is to perform design analyses for a non-nuclear hot-hydrogen materials tester, as a first step towards developing efficient and accurate multiphysics, thermo-fluid computational methodology to predict environments for hypothetical solid-core, nuclear thermal engine thrust chamber design and analysis. The computational methodology is based on a multidimensional, finite-volume, turbulent, chemically reacting, thermally radiating, unstructured-grid, and pressure-based formulation. The multiphysics invoked in this study include hydrogen dissociation kinetics and thermodynamics, turbulent flow, convective, and thermal radiative heat transfers. The goals of the design analyses are to maintain maximum hot-hydrogen jet impingement energy and to minimize chamber wall heating. The results of analyses on three test fixture configurations and the rationale for final selection are presented. The interrogation of physics revealed that reactions of hydrogen dissociation and recombination are highly correlated with local temperature and are necessary for accurate prediction of the hot-hydrogen jet temperature.
Protein binding hot spots prediction from sequence only by a new ensemble learning method.
Hu, Shan-Shan; Chen, Peng; Wang, Bing; Li, Jinyan
2017-10-01
Hot spots are interfacial core areas of binding proteins, which have been applied as targets in drug design. Experimental methods are costly in both time and expense to locate hot spot areas. Recently, in-silicon computational methods have been widely used for hot spot prediction through sequence or structure characterization. As the structural information of proteins is not always solved, and thus hot spot identification from amino acid sequences only is more useful for real-life applications. This work proposes a new sequence-based model that combines physicochemical features with the relative accessible surface area of amino acid sequences for hot spot prediction. The model consists of 83 classifiers involving the IBk (Instance-based k means) algorithm, where instances are encoded by important properties extracted from a total of 544 properties in the AAindex1 (Amino Acid Index) database. Then top-performance classifiers are selected to form an ensemble by a majority voting technique. The ensemble classifier outperforms the state-of-the-art computational methods, yielding an F1 score of 0.80 on the benchmark binding interface database (BID) test set. http://www2.ahu.edu.cn/pchen/web/HotspotEC.htm .
Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots
Wu, Zhen; Fallahi, Mohammad; Ouizem, Souad; Liu, Qin; Li, Weimin; Costi, Roberta; Roush, William R.; Bois, Philippe R. J.
2016-01-01
ABSTRACT Meiotic recombination initiates following the formation of DNA double-strand breaks (DSBs) by the Spo11 endonuclease early in prophase I, at discrete regions in the genome coined “hot spots.” In mammals, meiotic DSB site selection is directed in part by sequence-specific binding of PRDM9, a polymorphic histone H3 (H3K4Me3) methyltransferase. However, other chromatin features needed for meiotic hot spot specification are largely unknown. Here we show that the recombinogenic cores of active hot spots in mice harbor several histone H3 and H4 acetylation and methylation marks that are typical of open, active chromatin. Further, deposition of these open chromatin-associated histone marks is dynamic and is manifest at spermatogonia and/or pre-leptotene-stage cells, which facilitates PRDM9 binding and access for Spo11 to direct the formation of DSBs, which are initiated at the leptotene stage. Importantly, manipulating histone acetylase and deacetylase activities established that histone acetylation marks are necessary for both hot spot activity and crossover resolution. We conclude that there are functional roles for histone acetylation marks at mammalian meiotic recombination hot spots. PMID:27821479
NASA Astrophysics Data System (ADS)
Bonfand, M.; Belloche, A.; Menten, K. M.; Garrod, R. T.; Müller, H. S. P.
2017-08-01
Context. The Sagittarius B2 molecular cloud contains several sites forming high-mass stars. Sgr B2(N) is one of its main centers of activity. It hosts several compact and ultra-compact HII regions, as well as two known hot molecular cores (Sgr B2(N1) and Sgr B2(N2)) in the early stage of the high-mass star formation process, where complex organic molecules (COMs) are detected in the gas phase. Aims: Our goal is to use the high sensitivity of the Atacama Large Millimeter/submillimeter Array (ALMA) to characterize the hot core population in Sgr B2(N) and thereby shed new light on the star formation process in this star-forming region. Methods: We use a complete 3 mm spectral line survey conducted with ALMA to search for faint hot cores in the Sgr B2(N) region. The chemical composition of the detected sources and the column densities are derived by modeling the whole spectra under the assumption of local thermodynamic equilibrium. Population diagrams are constructed to fit rotational temperatures. Integrated intensity maps are produced to derive the peak position and fit the size of each molecule's emission distribution. The kinematic structure of the hot cores is investigated by analyzing the line wing emission of typical outflow tracers. The H2 column densities are computed from ALMA and SMA continuum emission maps. Results: We report the discovery of three new hot cores in Sgr B2(N) that we call Sgr B2(N3), Sgr B2(N4), and Sgr B2(N5). The three sources are associated with class II methanol masers, well known tracers of high-mass star formation, and Sgr B2(N5), also with a UCHII region. Their H2 column densities are found to be between approximately 16 and 36 times lower than the one of the main hot core Sgr B2(N1). The spectra of these new hot cores have spectral line densities of 11 up to 31 emission lines per GHz above the 7σ level, assigned to 22-25 molecules plus 13-20 less abundant isotopologs. We derive rotational temperatures of approximately 140-180 K for the three new hot cores and mean source sizes of 0.4″ for Sgr B2(N3) and 1.0″ for Sgr B2(N4) and Sgr B2(N5). The chemical composition of Sgr B2(N3), Sgr B2(N4), and Sgr B2(N5) is very similar, but it differs from that of Sgr B2(N2). Finally, Sgr B2(N3) and Sgr B2(N5) show high-velocity wing emission in typical outflow tracers, with a bipolar morphology in their integrated intensity maps suggesting the presence of an outflow, like in Sgr B2(N1). No sign of an outflow is found around Sgr B2(N2) and Sgr B2(N4). We derive statistical lifetimes of 4 × 104 yr for the class II methanol maser phase and 6 × 104 yr for the hot core phase in Sgr B2(N). Conclusions: The associations of the hot cores with class II methanol masers, outflows, and/or UCHII regions tentatively suggest the following age sequence: Sgr B2(N4), Sgr B2(N3), SgrB2(N5), Sgr B2(N1). The status of Sgr B2(N2) is unclear. It may contain two distinct sources, a UCHII region and a very young hot core.
ALMA Observations of the Archetypal “Hot Core” That Is Not: Orion-KL
DOE Office of Scientific and Technical Information (OSTI.GOV)
Orozco-Aguilera, M. T.; Zapata, Luis A.; Hirota, Tomoya
We present sensitive high angular resolution (∼0.″1–0.″3) continuum Atacama Large Millimeter/Submillimeter Array (ALMA) observations of the archetypal hot core located in the Orion Kleinmann-Low (KL) region. The observations were made in five different spectral bands (bands 3, 6, 7, 8, and 9) covering a very broad range of frequencies (149–658 GHz). Apart from the well-known millimeter emitting objects located in this region (Orion Source I and BN), we report the first submillimeter detection of three compact continuum sources (ALMA1–3) in the vicinities of the Orion-KL hot molecular core. These three continuum objects have spectral indices between 1.47 and 1.56, andmore » brightness temperatures between 100 and 200 K at 658 GHz, suggesting that we are seeing moderate, optically thick dust emission with possible grain growth. However, as these objects are not associated with warm molecular gas, and some of them are farther out from the molecular core, we thus conclude that they cannot heat the molecular core. This result favors the hypothesis that the hot molecular core in Orion-KL core is heated externally.« less
Preparing the optics technology to observe the hot universe
NASA Astrophysics Data System (ADS)
Bavdaz, Marcos; Wille, Eric; Wallace, Kotska; Shortt, Brian; Fransen, Sebastiaan; Collon, Maximilien; Ackermann, Marcelo; Vacanti, Giuseppe; Guenther, Ramses; Haneveld, Jeroen; Riekerink, Mark Olde; van Baren, Coen; Kampf, Dirk; Zuknik, Karl-Heinz; Christensen, Finn; Della Monica Ferreira, Desiree; Jakobsen, Anders Clemen; Krumrey, Michael; Müller, Peter; Burwitz, Vadim; Pareschi, Giovanni; Ghigo, Mauro
2014-07-01
With the selection of "The hot and energetic Universe" as science theme for ESA's second large class mission (L2) in the Cosmic Vision programme, work is focusing on the technology preparation for an advanced X-ray observatory. The core enabling technology for the high performance mirror is the Silicon Pore Optics (SPO) [1 to 23], a modular X-ray optics technology, which utilises processes and equipment developed for the semiconductor industry. The paper provides an overview of the programmatic background, the status of SPO technology and gives an outline of the development roadmap and activities undertaken and planned by ESA on optics, coatings [24 to 30] and test facilities [31, 33].
Williams-Bell, F Michael; Aisbett, Brad; Murphy, Bernadette A; Larsen, Brianna
2017-01-01
Background: The severity of wildland fires is increasing due to continually hotter and drier summers. Firefighters are required to make life altering decisions on the fireground, which requires analytical thinking, problem solving, and situational awareness. This study aimed to determine the effects of very hot (45°C; HOT) conditions on cognitive function following periods of simulated wildfire suppression work when compared to a temperate environment (18°C; CON). Methods: Ten male volunteer firefighters intermittently performed a simulated fireground task for 3 h in both the CON and HOT environments, with cognitive function tests (paired associates learning and spatial span) assessed at baseline (cog 1) and during the final 20-min of each hour (cog 2, 3, and 4). Reaction time was also assessed at cog 1 and cog 4. Pre- and post- body mass were recorded, and core and skin temperature were measured continuously throughout the protocol. Results: There were no differences between the CON and HOT trials for any of the cognitive assessments, regardless of complexity. While core temperature reached 38.7°C in the HOT (compared to only 37.5°C in the CON; p < 0.01), core temperature declined during the cognitive assessments in both conditions (at a rate of -0.15 ± 0.20°C·hr -1 and -0.63 ± 0.12°C·hr -1 in the HOT and CON trial respectively). Firefighters also maintained their pre-exercise body mass in both conditions, indicating euhydration. Conclusions: It is likely that this maintenance of euhydration and the relative drop in core temperature experienced between physical work bouts was responsible for the preservation of firefighters' cognitive function in the present study.
Williams-Bell, F. Michael; Aisbett, Brad; Murphy, Bernadette A.; Larsen, Brianna
2017-01-01
Background: The severity of wildland fires is increasing due to continually hotter and drier summers. Firefighters are required to make life altering decisions on the fireground, which requires analytical thinking, problem solving, and situational awareness. This study aimed to determine the effects of very hot (45°C; HOT) conditions on cognitive function following periods of simulated wildfire suppression work when compared to a temperate environment (18°C; CON). Methods: Ten male volunteer firefighters intermittently performed a simulated fireground task for 3 h in both the CON and HOT environments, with cognitive function tests (paired associates learning and spatial span) assessed at baseline (cog 1) and during the final 20-min of each hour (cog 2, 3, and 4). Reaction time was also assessed at cog 1 and cog 4. Pre- and post- body mass were recorded, and core and skin temperature were measured continuously throughout the protocol. Results: There were no differences between the CON and HOT trials for any of the cognitive assessments, regardless of complexity. While core temperature reached 38.7°C in the HOT (compared to only 37.5°C in the CON; p < 0.01), core temperature declined during the cognitive assessments in both conditions (at a rate of −0.15 ± 0.20°C·hr−1 and −0.63 ± 0.12°C·hr−1 in the HOT and CON trial respectively). Firefighters also maintained their pre-exercise body mass in both conditions, indicating euhydration. Conclusions: It is likely that this maintenance of euhydration and the relative drop in core temperature experienced between physical work bouts was responsible for the preservation of firefighters' cognitive function in the present study. PMID:29114230
Distribution of water in the G327.3-0.6 massive star-forming region
NASA Astrophysics Data System (ADS)
Leurini, S.; Herpin, F.; van der Tak, F.; Wyrowski, F.; Herczeg, G. J.; van Dishoeck, E. F.
2017-06-01
Aims: Following our past study of the distribution of warm gas in the G327.3-0.6 massive star-forming region, we aim here at characterizing the large-scale distribution of water in this active region of massive star formation made of individual objects in different evolutionary phases. We investigate possible variations of the water abundance as a function of evolution. Methods: We present Herschel/PACS (4'× 4') continuum maps at 89 and179 μm encompassing the whole region (Hii region and the infrared dark cloud, IRDC) and an APEX/SABOCA (2'× 2') map at 350 μm of the IRDC. New spectral Herschel/HIFI maps toward the IRDC region covering the low-energy water lines at 987 and 1113 GHz (and their H218O counterparts) are also presented and combined with HIFI pointed observations toward the G327 hot core region. We infer the physical properties of the gas through optical depth analysis and radiative transfer modeling of the HIFI lines. Results: The distribution of the continuum emission at 89 and 179 μm follows the thermal continuum emission observed at longer wavelengths, with a peak at the position of the hot core and a secondary peak in the Hii region, and an arch-like layer of hot gas west of this Hii region. The same morphology is observed in the p-H2O 111-000 line, in absorption toward all submillimeter dust condensations. Optical depths of approximately 80 and 15 are estimated and correspond to column densities of 1015 and 2 × 1014 cm-2, respectively, for the hot core and IRDC position. These values indicate an abundance of water relative to H2 of 3 × 10-8 toward the hot core, while the abundance of water does not change along the IRDC with values close to some 10-8. Infall (over at least 20″) is detected toward the hot core position with a rate of 1-1.3 × 10-2M⊙ /yr, high enough to overcome the radiation pressure that is due to the stellar luminosity. The source structure of the hot core region appears complex, with a cold outer gas envelope in expansion, situated between the outflow and the observer, extending over 0.32 pc. The outflow is seen face-on and rather centered away from the hot core. Conclusions: The distribution of water along the IRDC is roughly constant with an abundance peak in the more evolved object, that is, in the hot core. These water abundances are in agreement with previous studies in other massive objects and chemical models. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
Effects of Laser Frequency and Multiple Beams on Hot Electron Generation in Fast Ignition
NASA Astrophysics Data System (ADS)
Royle, Ryan B.
Inertial confinement fusion (ICF) is one approach to harnessing fusion power for the purpose of energy production in which a small deuterium-tritium capsule is imploded to about a thousand times solid density with ultra-intense lasers. In the fast ignition (FI) scheme, a picosecond petawatt laser pulse is used to deposit ˜10 kJ of energy in ˜10 ps into a small hot-spot at the periphery of the compressed core, igniting a fusion burn wave. FI promises a much higher energy gain over the conventional central hot-spot ignition scheme in which ignition is achieved through compression alone. Sufficient energy coupling between ignition laser and implosion core is critical for the feasibility of the FI scheme. Laser-core energy coupling is mediated by hot electrons which absorb laser energy near the critical density and propagate to the dense core, depositing their energy primarily through collisions. The hot electron energy distribution plays a large role in achieving efficient energy coupling since electrons with energy much greater than a few MeV will only deposit a small fraction of their energy into the hot-spot region due to reduced collisional cross section. It is understood that it may be necessary to use the second or third harmonic of the 1.05 mum Nd glass laser to reduce the average hot electron energy closer to the few-MeV range. Also, it is likely that multiple ignition beams will be used to achieve the required intensities. In this study, 2D particle-in-cell simulations are used to examine the effects of frequency doubling and tripling of a 1 mum laser as well as effects of using various dual-beam configurations. While the hot-electron energy spectrum is indeed shifted closer to the few-MeV range for higher frequency beams, the overall energy absorption is reduced, canceling the gain from higher efficiency. For a fixed total laser input energy, we find that the amount of hot electron energy able to be deposited into the core hot-spot is fairly insensitive to the laser configuration used. Our results hint that the more important issue at hand may be divergence and transport of the hot electrons, which tend to spray into 2pi radians due to instabilities and current filamentation present in the laser-plasma interaction region.
NASA Astrophysics Data System (ADS)
Takeda, Takeshi; Maruyama, Yu; Watanabe, Tadashi; Nakamura, Hideo
Experiments simulating PWR intermediate-break loss-of-coolant accidents (IBLOCAs) with 17% break at hot leg or cold leg were conducted in OECD/NEA ROSA-2 Project using the Large Scale Test Facility (LSTF). In the hot leg IBLOCA test, core uncovery started simultaneously with liquid level drop in crossover leg downflow-side before loop seal clearing (LSC) induced by steam condensation on accumulator coolant injected into cold leg. Water remained on upper core plate in upper plenum due to counter-current flow limiting (CCFL) because of significant upward steam flow from the core. In the cold leg IBLOCA test, core dryout took place due to rapid liquid level drop in the core before LSC. Liquid was accumulated in upper plenum, steam generator (SG) U-tube upflow-side and SG inlet plenum before the LSC due to CCFL by high velocity vapor flow, causing enhanced decrease in the core liquid level. The RELAP5/MOD3.2.1.2 post-test analyses of the two LSTF experiments were performed employing critical flow model in the code with a discharge coefficient of 1.0. In the hot leg IBLOCA case, cladding surface temperature of simulated fuel rods was underpredicted due to overprediction of core liquid level after the core uncovery. In the cold leg IBLOCA case, the cladding surface temperature was underpredicted too due to later core uncovery than in the experiment. These may suggest that the code has remaining problems in proper prediction of primary coolant distribution.
Structure-Based Design of Molecules to Reactivate Tumor-Derived p53 Mutations
2007-06-01
cluster in conserved regions or “hot spots” (Hainaut and Hollstein, 2000). Missense mutations leading to amino acid changes are the most common p53...domain stabilization compounds. Analysis of the residue-specific temperature factors of the high resolution core domain structure, coupled with a...second scoring results, 13 compounds (10 from the SPECS database and 3 from the TimTec database) were selected for further analysis using solution
NASA Astrophysics Data System (ADS)
Fuente, A.; Cernicharo, J.; Caselli, P.; McCoey, C.; Johnstone, D.; Fich, M.; van Kempen, T.; Palau, Aina; Yıldız, U. A.; Tercero, B.; López, A.
2014-08-01
Context. This paper is dedicated to the study of the chemistry of the intermediate-mass (IM) hot core NGC 7129 FIRS 2, probably the most compact warm core found in the 2-8 M⊙ stellar mass range. Aims: Our aim is to determine the chemical composition of the IM hot core NGC 7129 FIRS 2, and to provide new insights on the chemistry of hot cores in a more general context. Methods: NGC 7129 FIRS 2 (hereafter, FIRS 2) is located at a distance of 1250 pc and high spatial resolution observations are required to resolve the hot core at its center. We present a molecular survey from 218 200 MHz to 221 800 MHz carried out with the IRAM Plateau de Bure Interferometer (PdBI). These observations were complemented with a long integration single-dish spectrum taken with the IRAM 30 m telescope in Pico de Veleta (Spain). We used a local thermodynamic equilibrium (LTE) single temperature code to model the whole dataset. Results: The interferometric spectrum is crowded with a total of ≈300 lines from which a few dozen remain unidentified. The spectrum has been modeled with a total of 20 species and their isomers, isotopologues, and deuterated compounds. Complex molecules like methyl formate (CH3OCHO), ethanol (CH3CH2OH), glycolaldehyde (CH2OHCHO), acetone (CH3COCH3), dimethyl ether (CH3OCH3), ethyl cyanide (CH3CH2CN), and the aGg' conformer of ethylene glycol (aGg'-(CH2OH)2) are among the detected species. The detection of vibrationally excited lines of CH3CN, CH3OCHO, CH3OH, OCS, HC3N, and CH3CHO proves the existence of gas and dust at high temperatures. The gas kinetic temperature estimated from the vibrational lines of CH3CN, ~405-67+100 K, is similar to that measured in massive hot cores. Our data allow an extensive comparison of the chemistry in FIRS 2 and the Orion hot core. Conclusions: We find a quite similar chemistry in FIRS 2 and Orion. Most of the studied fractional molecular abundances agree within a factor of 5. Larger differences are only found for the deuterated compounds D2CO and CH2DOH and a few molecules (CH3CH2CN, SO2, HNCO and CH3CHO). Since the physical conditions are similar in both hot cores, only different initial conditions (warmer pre-collapse and collapse phase in the case of Orion) and/or different crossing times of the gas in the hot core can explain this behavior. We discuss these two scenarios. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain).Appendices are available in electronic form at http://www.aanda.orgThe interferometrid spectra of Fig. A.1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/568/A65
NASA Astrophysics Data System (ADS)
Choudhury, R.; Schilke, P.; Stéphan, G.; Bergin, E.; Möller, T.; Schmiedeke, A.; Zernickel, A.
2015-03-01
Context. Hot molecular cores (HMCs) are intermediate stages of high-mass star formation and are also known for their rich chemical reservoirs and emission line spectra at (sub-)mm wavebands. Complex organic molecules (COMs) such as methanol (CH3OH), ethanol (C2H5OH), dimethyl ether (CH3OCH3), and methyl formate (HCOOCH3) produce most of these observed lines. The observed spectral feature of HMCs such as total number of emission lines and associated line intensities are also found to vary with evolutionary stages. Aims: We aim to investigate the spectral evolution of these COMs to explore the initial evolutionary stages of high-mass star formation including HMCs. Methods: We developed various 3D models for HMCs guided by the evolutionary scenarios proposed by recent empirical and modeling studies. We then investigated the spatio-temporal variation of temperature and molecular abundances in HMCs by consistently coupling gas-grain chemical evolution with radiative transfer calculations. We explored the effects of varying physical conditions on molecular abundances including density distribution and luminosity evolution of the central protostar(s) among other parameters. Finally, we simulated the synthetic spectra for these models at different evolutionary timescales to compare with observations. Results: Temperature has a profound effect on the formation of COMs through the depletion and diffusion on grain surface to desorption and further gas-phase processing. The time-dependent temperature structure of the hot core models provides a realistic framework for investigating the spatial variation of ice mantle evaporation as a function of evolutionary timescales. We find that a slightly higher value (15 K) than the canonical dark cloud temperature (10 K) provides a more productive environment for COM formation on grain surface. With increasing protostellar luminosity, the water ice evaporation font (~100 K) expands and the spatial distribution of gas phase abundances of these COMs also spreads out. We calculated the temporal variation of the radial profiles of these COMs for different hot core models. These profiles resemble the so-called jump profiles with relative abundances higher than 10-9 within the evaporation font will furthermore be useful to model the observed spectra of hot cores. We present the simulated spectra of these COMs for different hot core models at various evolutionary timescales. A qualitative comparison of the simulated and observed spectra suggests that these self-consistent hot core models can reproduce the notable trends in hot core spectral variation within the typical hot core timescales of 105 year. These models predict that the spatial distribution of various emission line maps will also expand with evolutionary time; this feature can be used to constrain the relative desorption energies of the molecules that mainly form on the grain surface and return to the gas phase via thermal desorption. The detailed modeling of the thermal structure of hot cores with similar masses along with the characterization of the desorption energies of different molecules can be used to constrain the luminosity evolution of the central protostars. The model predictions can be compared with high resolution observation that can probe scales of a few thousand AU in high-mass star forming regions such as from Atacama Large Millimeter/submillimeter Array (ALMA). We used a spectral fitting method to analyze the simulated spectra and find that it significantly underestimates some of the physical parameters such as temperature. The coupling of chemical evolution with radiative transfer models will be particularly useful to decipher the physical structure of hot cores and also to constrain the initial evolutionary stages of high-mass star formation. Appendices are available in electronic form at http://www.aanda.org
Hot super-Earths and giant planet cores from different migration histories
NASA Astrophysics Data System (ADS)
Cossou, Christophe; Raymond, Sean N.; Hersant, Franck; Pierens, Arnaud
2014-09-01
Planetary embryos embedded in gaseous protoplanetary disks undergo Type I orbital migration. Migration can be inward or outward depending on the local disk properties but, in general, only planets more massive than several M⊕ can migrate outward. Here we propose that an embryo's migration history determines whether it becomes a hot super-Earth or the core of a giant planet. Systems of hot super-Earths (or mini-Neptunes) form when embryos migrate inward and pile up at the inner edge of the disk. Giant planet cores form when inward-migrating embryos become massive enough to switch direction and migrate outward. We present simulations of this process using a modified N-body code, starting from a swarm of planetary embryos. Systems of hot super-Earths form in resonant chains with the innermost planet at or interior to the disk inner edge. Resonant chains are disrupted by late dynamical instabilities triggered by the dispersal of the gaseous disk. Giant planet cores migrate outward toward zero-torque zones, which move inward and eventually disappear as the disk disperses. Giant planet cores migrate inward with these zones and are stranded at ~1-5 AU. Our model reproduces several properties of the observed extra-solar planet populations. The frequency of giant planet cores increases strongly when the mass in solids is increased, consistent with the observed giant exoplanet - stellar metallicity correlation. The frequency of hot super-Earths is not a function of stellar metallicity, also in agreement with observations. Our simulations can reproduce the broad characteristics of the observed super-Earth population.
NASA Astrophysics Data System (ADS)
Stevens, Adam R. H.; Lagos, Claudia del P.; Contreras, Sergio; Croton, Darren J.; Padilla, Nelson D.; Schaller, Matthieu; Schaye, Joop; Theuns, Tom
2017-05-01
We use the hydrodynamic, cosmological EAGLE simulations to investigate how the hot gas in haloes condenses to form and grow galaxies. We select haloes from the simulations that are actively cooling and study the temperature, distribution and metallicity of their hot, cold and transitioning 'cooling' gas, placing these in the context of semi-analytic models. Our selection criteria lead us to focus on Milky Way-like haloes. We find that the hot-gas density profiles of the haloes form a progressively stronger core over time, the nature of which can be captured by a β profile that has a simple dependence on redshift. In contrast, the hot gas that will cool over a time-step is broadly consistent with a singular isothermal sphere. We find that cooling gas carries a few times the specific angular momentum of the halo and is offset in spin direction from the rest of the hot gas. The gas loses ˜60 per cent of its specific angular momentum during the cooling process, generally remaining greater than that of the halo, and it precesses to become aligned with the cold gas already in the disc. We find tentative evidence that angular-momentum losses are slightly larger when gas cools on to dispersion-supported galaxies. We show that an exponential surface density profile for gas arriving on a disc remains a reasonable approximation, but a cusp containing ˜20 per cent of the mass is always present, and disc scale radii are larger than predicted by a vanilla Fall & Efstathiou model. These scale radii are still closely correlated with the halo spin parameter, for which we suggest an updated prescription for galaxy formation models.
Rhapsody-G simulations I: the cool cores, hot gas and stellar content of massive galaxy clusters
Hahn, Oliver; Martizzi, Davide; Wu, Hao -Yi; ...
2017-01-25
We present the rhapsody-g suite of cosmological hydrodynamic zoom simulations of 10 massive galaxy clusters at the M vir ~10 15 M ⊙ scale. These simulations include cooling and subresolution models for star formation and stellar and supermassive black hole feedback. The sample is selected to capture the whole gamut of assembly histories that produce clusters of similar final mass. We present an overview of the successes and shortcomings of such simulations in reproducing both the stellar properties of galaxies as well as properties of the hot plasma in clusters. In our simulations, a long-lived cool-core/non-cool-core dichotomy arises naturally, andmore » the emergence of non-cool cores is related to low angular momentum major mergers. Nevertheless, the cool-core clusters exhibit a low central entropy compared to observations, which cannot be alleviated by thermal active galactic nuclei feedback. For cluster scaling relations, we find that the simulations match well the M 500–Y 500 scaling of Planck Sunyaev–Zeldovich clusters but deviate somewhat from the observed X-ray luminosity and temperature scaling relations in the sense of being slightly too bright and too cool at fixed mass, respectively. Stars are produced at an efficiency consistent with abundance-matching constraints and central galaxies have star formation rates consistent with recent observations. In conclusion, while our simulations thus match various key properties remarkably well, we conclude that the shortcomings strongly suggest an important role for non-thermal processes (through feedback or otherwise) or thermal conduction in shaping the intracluster medium.« less
rhapsody-g simulations - I. The cool cores, hot gas and stellar content of massive galaxy clusters
NASA Astrophysics Data System (ADS)
Hahn, Oliver; Martizzi, Davide; Wu, Hao-Yi; Evrard, August E.; Teyssier, Romain; Wechsler, Risa H.
2017-09-01
We present the rhapsody-g suite of cosmological hydrodynamic zoom simulations of 10 massive galaxy clusters at the Mvir ˜ 1015 M⊙ scale. These simulations include cooling and subresolution models for star formation and stellar and supermassive black hole feedback. The sample is selected to capture the whole gamut of assembly histories that produce clusters of similar final mass. We present an overview of the successes and shortcomings of such simulations in reproducing both the stellar properties of galaxies as well as properties of the hot plasma in clusters. In our simulations, a long-lived cool-core/non-cool-core dichotomy arises naturally, and the emergence of non-cool cores is related to low angular momentum major mergers. Nevertheless, the cool-core clusters exhibit a low central entropy compared to observations, which cannot be alleviated by thermal active galactic nuclei feedback. For cluster scaling relations, we find that the simulations match well the M500-Y500 scaling of Planck Sunyaev-Zeldovich clusters but deviate somewhat from the observed X-ray luminosity and temperature scaling relations in the sense of being slightly too bright and too cool at fixed mass, respectively. Stars are produced at an efficiency consistent with abundance-matching constraints and central galaxies have star formation rates consistent with recent observations. While our simulations thus match various key properties remarkably well, we conclude that the shortcomings strongly suggest an important role for non-thermal processes (through feedback or otherwise) or thermal conduction in shaping the intracluster medium.
Correlation of Wissler Human Thermal Model Blood Flow and Shiver Algorithms
NASA Technical Reports Server (NTRS)
Bue, Grant; Makinen, Janice; Cognata, Thomas
2010-01-01
The Wissler Human Thermal Model (WHTM) is a thermal math model of the human body that has been widely used to predict the human thermoregulatory response to a variety of cold and hot environments. The model has been shown to predict core temperature and skin temperatures higher and lower, respectively, than in tests of subjects in crew escape suit working in a controlled hot environments. Conversely the model predicts core temperature and skin temperatures lower and higher, respectively, than in tests of lightly clad subjects immersed in cold water conditions. The blood flow algorithms of the model has been investigated to allow for more and less flow, respectively, for the cold and hot case. These changes in the model have yielded better correlation of skin and core temperatures in the cold and hot cases. The algorithm for onset of shiver did not need to be modified to achieve good agreement in cold immersion simulations
Advancements Toward Oil-Free Rotorcraft Propulsion
NASA Technical Reports Server (NTRS)
Howard, Samuel A.; Bruckner, Robert J.; Radil, Kevin C.
2010-01-01
NASA and the Army have been working for over a decade to advance the state-of-the-art (SOA) in Oil-Free Turbomachinery with an eye toward reduced emissions and maintenance, and increased performance and efficiency among other benefits. Oil-Free Turbomachinery is enabled by oil-free gas foil bearing technology and relatively new high-temperature tribological coatings. Rotorcraft propulsion is a likely candidate to apply oil-free bearing technology because the engine size class matches current SOA for foil bearings and because foil bearings offer the opportunity for higher speeds and temperatures and lower weight, all critical issues for rotorcraft engines. This paper describes an effort to demonstrate gas foil journal bearing use in the hot section of a full-scale helicopter engine core. A production engine hot-core location is selected as the candidate foil bearing application. Rotordynamic feasibility, bearing sizing, and load capability are assessed. The results of the program will help guide future analysis and design in this area by documenting the steps required and the process utilized for successful application of oil-free technology to a full-scale engine.
Low density bismaleimide-carbon microballoon composites. [aircraft and submarine compartment safety
NASA Technical Reports Server (NTRS)
Kourtides, D. A.; Parker, J. A. (Inventor)
1978-01-01
A process is described for constructing for a composite laminate structure which exhibits a high resistance to heat and flame provides safer interior structures for aircraft and submarine compartments. Composite laminate structures are prepared by the bismaleimide resin preimpregnation of a fiberglass cloth to form a face sheet which is bonded with a bismaleimide hot melt adhesive to a porous core structure selected from the group consisting of polyamide paper and bismaleimide-glass fabric which is filled with carbon microballoons. The carbon microballoons are prepared by pyrolyzing phenolic micro-balloons in the presence of nitrogen. A slurry of the carbon microballoons is prepared to fill the porous core structure. The porous core structure and face sheet are bonded to provide panel structures exhibiting increased mechanical capacities and lower oxygen limit values and smoke density values.
Heating mechanisms for intermittent loops in active region cores from AIA/SDO EUV observations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cadavid, A. C.; Lawrence, J. K.; Christian, D. J.
2014-11-01
We investigate intensity variations and energy deposition in five coronal loops in active region cores. These were selected for their strong variability in the AIA/SDO 94 Å intensity channel. We isolate the hot Fe XVIII and Fe XXI components of the 94 Å and 131 Å by modeling and subtracting the 'warm' contributions to the emission. HMI/SDO data allow us to focus on 'inter-moss' regions in the loops. The detailed evolution of the inter-moss intensity time series reveals loops that are impulsively heated in a mode compatible with a nanoflare storm, with a spike in the hot 131 Å signalsmore » leading and the other five EUV emission channels following in progressive cooling order. A sharp increase in electron temperature tends to follow closely after the hot 131 Å signal confirming the impulsive nature of the process. A cooler process of growing emission measure follows more slowly. The Fourier power spectra of the hot 131 Å signals, when averaged over the five loops, present three scaling regimes with break frequencies near 0.1 min{sup –1} and 0.7 min{sup –1}. The low frequency regime corresponds to 1/f noise; the intermediate indicates a persistent scaling process and the high frequencies show white noise. Very similar results are found for the energy dissipation in a 2D 'hybrid' shell model of loop magneto-turbulence, based on reduced magnetohydrodynamics, that is compatible with nanoflare statistics. We suggest that such turbulent dissipation is the energy source for our loops.« less
Heat exchanger for coal gasification process
Blasiole, George A.
1984-06-19
This invention provides a heat exchanger, particularly useful for systems requiring cooling of hot particulate solids, such as the separated fines from the product gas of a carbonaceous material gasification system. The invention allows effective cooling of a hot particulate in a particle stream (made up of hot particulate and a gas), using gravity as the motive source of the hot particulate. In a preferred form, the invention substitutes a tube structure for the single wall tube of a heat exchanger. The tube structure comprises a tube with a core disposed within, forming a cavity between the tube and the core, and vanes in the cavity which form a flow path through which the hot particulate falls. The outside of the tube is in contact with the cooling fluid of the heat exchanger.
de Kock, Leanne; Bah, Ismaël; Revil, Timothée; Bérubé, Pierre; Wu, Mona K; Sabbaghian, Nelly; Priest, John R; Ragoussis, Jiannis; Foulkes, William D
2016-10-01
Nontoxic multinodular goiter (MNG) occurs frequently, but its genetic etiology is not well established. Familial MNG and MNG occurring with ovarian Sertoli-Leydig cell tumor are associated with germline DICER1 mutations. We recently identified second somatic DICER1 ribonuclease (RNase) IIIb mutations in two MNGs. The objective of the study was to investigate the occurrence of somatic DICER1 mutations and mutational clonality in MNG. MNGs from 15 patients (10 with and five without germline DICER1 mutations) were selected based on tissue availability. Core biopsies/scrapings (n = 70) were obtained, sampling areas of follicular hyperplasia, hyperplasia within colloid pools, unremarkable thyroid parenchyma, and areas of thyroid parenchyma, not classified. After capture with a Fluidigm access array, the coding sequence of DICER1 was deep sequenced using DNA from each core/scraping. All germline DICER1-mutated cases were found to harbor at least one RNase III mutation. Specifically, we identified 12 individually distinct DICER1 RNase IIIb hot spot mutations in 32 of the follicular hyperplasia or hyperplasia within colloid pools cores/scrapings. These mutations are predicted to affect the metal-ion binding residues at positions p.Glu1705, p.Asp1709, p.Gly1809, p.Asp1810, and p.Glu1813. Somatic RNase IIIb mutations were identified in the 10 DICER1 germline mutated MNGs as follows: two cases contained one somatic mutation, five cases contained two mutations, and three cases contained three distinct somatic hot spot mutations. No RNase IIIb mutations were identified in the MNGs from individuals without germline DICER1 mutations. This study demonstrates that nodules within MNG occurring in DICER1 syndrome are associated with spatially distributed somatic DICER1 RNase IIIb mutations.
Detection of Ketenimine (CH2CNH) in SGRB2(N) Hot Cores
NASA Technical Reports Server (NTRS)
Lovas, F. J.; Hollis, J. M.; Remijan, Anthony J.; Jewell, P. R.
2006-01-01
Ketenimine (CH2CNH) has been detected in absorption toward the starforming region Sagittarius B2(N) with the 100-m Green Bank Telescope (GBT) by means of three rotational transitions: 7(sub 16)-8(sub 08) at 41.5 GHz, 8(sub 19)-9(sub 09), at 23.2 GHz, and 9(sub 18)-10(sub 0,10) at 4.9 GHz. Ketenimine has a sparse rotational spectrum below 50 GHz. From transition line strength arguments, the spectral lines found are the ones most likely to be detected and occur in spectral regions that have little possibility of confusion with other molecular species. Partially resolved hyperfine structure is apparent in the 4.9 GHz transition which has energy levels approximately 50 K above ground state level; the absorption seen in this transition appears to be emanating from gas in close proximity to the LMH hot core that has a systemic LSR velocity of +64 kilometers per second. By comparison, the 41.5 GHz and 23.2 GHz transitions have lower energy levels of approximately 33 K and approximately 41 K, respectively; and show absorption against the two star-forming SgrB2(N) hot cores with systematic LSR velocities of +64 (the LMH) and +82 kilometers per second. These ketenimine data show that the hot core at +82 kilometers per second is cooler than the hot core at +64 kilometers per second. Ketenimine is likely formed directly from its isomer methyl cyanide (CH3CN) by tautomerization driven by shocks that pervade the star-forming region.
Fuel handling system for a nuclear reactor
Saiveau, James G.; Kann, William J.; Burelbach, James P.
1986-01-01
A pool type nuclear fission reactor has a core, with a plurality of core elements and a redan which confines coolant as a hot pool at a first end of the core separated from a cold pool at a second end of the core by the redan. A fuel handling system for use with such reactors comprises a core element storage basket located outside of the redan in the cold pool. An access passage is formed in the redan with a gate for opening and closing the passage to maintain the temperature differential between the hot pool and the cold pool. A mechanism is provided for opening and closing the gate. A lifting arm is also provided for manipulating the fuel core elements through the access passage between the storage basket and the core when the redan gate is open.
Fuel handling system for a nuclear reactor
Saiveau, James G.; Kann, William J.; Burelbach, James P.
1986-12-02
A pool type nuclear fission reactor has a core, with a plurality of core elements and a redan which confines coolant as a hot pool at a first end of the core separated from a cold pool at a second end of the core by the redan. A fuel handling system for use with such reactors comprises a core element storage basket located outside of the redan in the cold pool. An access passage is formed in the redan with a gate for opening and closing the passage to maintain the temperature differential between the hot pool and the cold pool. A mechanism is provided for opening and closing the gate. A lifting arm is also provided for manipulating the fuel core elements through the access passage between the storage basket and the core when the redan gate is open.
The Complete Local-Volume Groups Sample (CLoGS): Early results from X-ray and radio observations
NASA Astrophysics Data System (ADS)
Vrtilek, Jan M.; O'Sullivan, Ewan; David, Laurence P.; Giacintucci, Simona; Kolokythas, Konstantinos
2017-08-01
Although the group environment is the dominant locus of galaxy evolution (in contrast to rich clusters, which contain only a few percent of galaxies), there has been a lack of reliable, representative group samples in the local Universe. In particular, X-ray selected samples are strongly biased in favor of the X-ray bright, centrally-concentrated cool-core systems. In response, we have designed the Complete Local-Volume Groups Sample (CLoGS), an optically-selected statistically-complete sample of 53 groups within 80 Mpc which is intended to overcome the limitations of X-ray selected samples and serve as a representative survey of groups in the local Universe. We have supplemented X-ray data from Chandra and XMM (70% complete to date, using both archival and new observations, with a 26-group high richness subsample 100% complete) with GMRT radio continuum observations (at 235 and 610 MHz, complete for the entire sample). CLoGS includes groups with a wide variety of properties in terms of galaxy population, hot gas content, and AGN power. We here describe early results from the survey, including the range of AGN activity observed in the dominant galaxies, the relative fraction of cool-core and non-cool-core groups in our sample, and the degree of disturbance observed in the IGM.
Melt infiltration of silicon carbide compacts. II - Evaluation of solidification microstructures
NASA Technical Reports Server (NTRS)
Asthana, Rajiv; Rohatgi, Pradeep K.
1993-01-01
Microstructural aspects of alloy solidification within the interstices of porous compacts of platelet-shaped single crystals of alpha-SiC, when the latter are infiltrated with a hot metal under pressure, have been described. Microstructural evidence is presented of selective reorientation of platelets and nonhomogeneous solute distribution under shear of pressurized melt, of constrained growth of primary solid within finite width zones, and of the modulation of coring due to microsegregation as a result of variations in the pore size of compacts.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Umair Siddiqui, M., E-mail: musiddiqui@wisc.edu; Hershkowitz, Noah
2014-02-15
A hot (T{sub e} ≈ 10 eV) electron population is observed in the core of a 3 mTorr argon helicon plasma source at 500 W RF power and 900 G uniform axial magnetic field strength, 12 cm from the edge of the helicon antenna. A double layer-like structure consisting of a localized axial electric field of approximately 8 V/cm over 1–2 cm is observed adjacent to the hot electron population. The potential step generated by the electric field is shown to be large enough to trap the hot electrons. To our knowledge this is the first observation of these structures in the core of amore » helicon discharge.« less
Yamaguchi, S; Igami, H; Tanaka, H; Maekawa, T
2004-07-23
Sawtooth crashes in an Ohmically heated plasma in the WT-3 tokamak have been observed by using soft x-ray computer tomography at three different poloidal cross sections around the torus. Initially, collapsing proceeds slowly with keeping the helical structure of an m = 1/n = 1 hot core around the torus. It accelerates as the helical hot structure is strongly deformed and fades away in the manner that the hot core at the high field side becomes obscure and disappears, while that at the low field side is deformed into a thin crescent aligned along the inversion circle, which survives even at the completion of the crash. Copyright 2004 The American Physical Society
The critical limiting temperature and selective brain cooling: neuroprotection during exercise?
Marino, Frank E
2011-01-01
There is wide consensus that long duration exercise in the heat is impaired compared with cooler conditions. A common observation when examining exercise tolerance in the heat in laboratory studies is the critical limiting core temperature (CLT) and the apparent attenuation in central nervous system (CNS) drive leading to premature fatigue. Selective brain cooling (SBC) purportedly confers neuroprotection during exercise heat stress by attenuating the increase in brain temperature. As the CLT is dependent on heating to invoke a reduction in efferent drive, it is thus not compatible with SBC which supposedly attenuates the rise in brain temperature. Therefore, the CLT and SBC hypotheses cannot be complimentary if the goal is to confer neuroprotection from thermal insult as it is counter-intuitive to selectively cool the brain if the purpose of rising brain temperature is to down-regulate skeletal muscle recruitment. This presents a circular model for which there is no apparent end to the ultimate physiological outcome; a 'hot brain' selectively cooled in order to reduce the CNS drive to skeletal muscle. This review will examine the postulates of the CLT and SBC with their relationship to the avoidance of a 'hot brain' which together argue for a theoretical position against neuroprotection as the key physiological strategy in exercise-induced hyperthermia.
NASA Technical Reports Server (NTRS)
dePater, I.; Hollenbach, D. J.; Charnley, S. B.
1999-01-01
In protostellar cores where the dust temperature has been raised above 100K and subsequently allowed to fall below the condensation temperature of methanol, recondensation on to cooling grains removes methanol molecules from the gas at rates.faster (about 1000 times) than those of chemical reactions. Molecular recondensation can have a profound effect on the chemical composition of hot cores. The methanol chemistry of hot cores is solved analytically and the trend in molecule binding energies required is compared with theoretical and experimental values. It is demonstrated, through a model calculation incorporating recondensation, that it yields a consistent explanation of the similarity of the CH3OH , CH3OCH3 and HCOOCH3 abundances measured in G34.3 and W3(H2O). These observations suggest that the latter molecules could not be derived from CH3OH through gas phase reactions. The manner in which molecular recondensation could affect the interpretation of hot core chemistry in general, particularly of organic molecules, is briefly discussed.
The Formation of Glycine in Hot Cores: New Gas-grain Chemical Simulations of Star-forming Regions
NASA Astrophysics Data System (ADS)
Garrod, Robin
2012-07-01
Organic molecules of increasing complexity have been detected in the warm envelopes of star-forming cores, commonly referred to as "hot cores". Spectroscopic searches at mm/sub-mm wavelengths have uncovered both amines and carboxylic acids in these regions, as well as a range of other compounds including alcohols, ethers, esters, and nitriles. However, the simplest amino acid, glycine (NH2CH2COOH), has not yet been reliably detected in the ISM. There has been much interest in this molecule, due to its importance to the formation of proteins, and to life, while the positive identification of interstellar molecules of similar or greater complexity suggests that its existence in star-forming regions is plausible. I will present the results of recent models of hot-core chemistry that simulate the formation of both simple and complex molecules on the surfaces or within the ice mantles of dust grains. I will also present results from the first gas-grain astrochemical model to approach the question of amino-acid formation in hot cores. The formation of glycine in moderate abundance is found to be as efficient as that for similarly complex species, while its sublimation from the grains occurs at somewhat higher temperatures. However, simulated emission spectra based on the model results show that the degree of compactness of high-abundance regions, and the density and temperature profiles of the cores may be the key variables affecting the future detection of glycine, as well as other amino acids, and may explain its non-detection to date.
Hydrogen isotope exchanges between water and methanol in interstellar ices
NASA Astrophysics Data System (ADS)
Faure, A.; Faure, M.; Theulé, P.; Quirico, E.; Schmitt, B.
2015-12-01
The deuterium fractionation of gas-phase molecules in hot cores is believed to reflect the composition of interstellar ices. The deuteration of methanol is a major puzzle, however, because the isotopologue ratio [CH2DOH]/[CH3OD], which is predicted to be equal to 3 by standard grain chemistry models, is much larger (~20) in low-mass hot corinos and significantly lower (~1) in high-mass hot cores. This dichotomy in methanol deuteration between low-mass and massive protostars is currently not understood. In this study, we report a simplified rate equation model of the deuterium chemistry occurring in the icy mantles of interstellar grains. We apply this model to the chemistry of hot corinos and hot cores, with IRAS 16293-2422 and the Orion KL Compact Ridge as prototypes, respectively. The chemistry is based on a statistical initial deuteration at low temperature followed by a warm-up phase during which thermal hydrogen/deuterium (H/D) exchanges occur between water and methanol. The exchange kinetics is incorporated using laboratory data. The [CH2DOH]/[CH3OD] ratio is found to scale inversely with the D/H ratio of water, owing to the H/D exchange equilibrium between the hydroxyl (-OH) functional groups of methanol and water. Our model is able to reproduce the observed [CH2DOH]/[CH3OD] ratios provided that the primitive fractionation of water ice [HDO]/[H2O] is ~2% in IRAS 16293-2422 and ~0.6% in Orion KL. We conclude that the molecular D/H ratios measured in hot cores may not be representative of the original mantles because molecules with exchangeable deuterium atoms can equilibrate with water ice during the warm-up phase.
Interferometric observations of large biologically interesting interstellar and cometary molecules
Snyder, Lewis E.
2006-01-01
Interferometric observations of high-mass regions in interstellar molecular clouds have revealed hot molecular cores that have substantial column densities of large, partly hydrogen-saturated molecules. Many of these molecules are of interest to biology and thus are labeled “biomolecules.” Because the clouds containing these molecules provide the material for star formation, they may provide insight into presolar nebular chemistry, and the biomolecules may provide information about the potential of the associated interstellar chemistry for seeding newly formed planets with prebiotic organic chemistry. In this overview, events are outlined that led to the current interferometric array observations. Clues that connect this interstellar hot core chemistry to the solar system can be found in the cometary detection of methyl formate and the interferometric maps of cometary methanol. Major obstacles to understanding hot core chemistry remain because chemical models are not well developed and interferometric observations have not been very sensitive. Differentiation in the molecular isomers glycolaldehdye, methyl formate, and acetic acid has been observed, but not explained. The extended source structure for certain sugars, aldehydes, and alcohols may require nonthermal formation mechanisms such as shock heating of grains. Major advances in understanding the formation chemistry of hot core species can come from observations with the next generation of sensitive, high-resolution arrays. PMID:16894168
Absence of a Metallicity Effect for Ultra-short-period Planets
DOE Office of Scientific and Technical Information (OSTI.GOV)
Winn, Joshua N.; Sanchis-Ojeda, Roberto; Isaacson, Howard
Ultra-short-period (USP) planets are a newly recognized class of planets with periods shorter than one day and radii smaller than about 2 R {sub ⊕}. It has been proposed that USP planets are the solid cores of hot Jupiters that have lost their gaseous envelopes due to photo-evaporation or Roche lobe overflow. We test this hypothesis by asking whether USP planets are associated with metal-rich stars, as has long been observed for hot Jupiters. We find the metallicity distributions of USP-planet and hot-Jupiter hosts to be significantly different ( p = 3 × 10{sup −4}) based on Keck spectroscopy ofmore » Kepler stars. Evidently, the sample of USP planets is not dominated by the evaporated cores of hot Jupiters. The metallicity distribution of stars with USP planets is indistinguishable from that of stars with short-period planets with sizes between 2 and 4 R {sub ⊕}. Thus, it remains possible that the USP planets are the solid cores of formerly gaseous planets that are smaller than Neptune.« less
Discovery of the Closest Hot Subdwarf Binary with White Dwarf Companion
NASA Astrophysics Data System (ADS)
Geier, S.; Marsh, T. R.; Dunlap, B. H.; Barlow, B. N.; Schaffenroth, V.; Ziegerer, E.; Heber, U.; Kupfer, T.; Maxted, P. F. L.; Miszalski, B.; Shporer, A.; Telting, J. H.; Ostensen, R. H.; O'Toole, S. J.; Gänsicke, B. T.; Napiwotzki, R.
2013-01-01
We report the discovery of an extremely close, eclipsing binary system. A white dwarf is orbited by a core He-burning compact hot subdwarf star with a period as short as ≃ 0.04987 d making this system the most compact hot subdwarf binary discovered so far. The subdwarf will start to transfer helium-rich material on short timescales of less than 50 Myr. The ignition of He-burning at the surface may trigger carbon-burning in the core although the WD is less massive than the Chandrasekhar limit (> 0.74 M⊙) making this binary a possible progenitor candidate for a supernova type Ia event.
Direct heating of a laser-imploded core using ultraintense laser LFEX
NASA Astrophysics Data System (ADS)
Kitagawa, Y.; Mori, Y.; Ishii, K.; Hanayama, R.; Nishimura, Y.; Okihara, S.; Nakayama, S.; Sekine, T.; Takagi, M.; Watari, T.; Satoh, N.; Kawashima, T.; Komeda, O.; Hioki, T.; Motohiro, T.; Azuma, H.; Sunahara, A.; Sentoku, Y.; Arikawa, Y.; Abe, Y.; Miura, E.; Ozaki, T.
2017-07-01
A CD shell was preimploded by two counter-propagating green beams from the GEKKO laser system GXII (based at the Institute of Laser Engineering, Osaka University), forming a dense core. The core was predominantly heated by energetic ions driven by the laser for fast-ignition-fusion experiment, an extremely energetic ultrashort pulse laser, that is illuminated perpendicularly to the GXII axis. Consequently, we observed the D(d, n)3 He-reacted neutrons (DD beam-fusion neutrons) at a yield of 5× {{10}8} n/4π sr. The beam-fusion neutrons verified that the ions directly collided with the core plasma. Whereas the hot electrons heated the whole core volume, the energetic ions deposited their energies locally in the core. As evidenced in the spectrum, the process simultaneously excited thermal neutrons with a yield of 6× {{10}7} n/4π sr, raising the local core temperature from 0.8 to 1.8 keV. The shell-implosion dynamics (including the beam fusion and thermal fusion initiated by fast deuterons and carbon ions) can be explained by the one-dimensional hydrocode STAR 1D. Meanwhile, the core heating due to resistive processes driven by hot electrons, and also the generation of fast ions were well-predicted by the two-dimensional collisional particle-in-cell code. Together with hot electrons, the ion contribution to fast ignition is indispensable for realizing high-gain fusion. By virtue of its core heating and ignition, the proposed scheme can potentially achieve high-gain fusion.
Girard, Olivier; Brocherie, Franck; Morin, Jean-Benoit; Millet, Grégoire P
2016-01-01
We determined if performance and mechanical running alterations during repeated treadmill sprinting differ between severely hot and hypoxic environments. Six male recreational sportsmen (team- and racket-sport background) performed five 5-s sprints with 25-s recovery on an instrumented treadmill, allowing the continuous (step-by-step) measurement of running kinetics/kinematics and spring-mass characteristics. These were randomly conducted in control (CON; 25°C/45% RH, inspired fraction of oxygen = 20.9%), hot (HOT; 38°C/21% RH, inspired fraction of oxygen = 20.9%; end-exercise core temperature: ~38.6°C) and normobaric hypoxic (HYP, 25°C/45% RH, inspired fraction of oxygen = 13.3%/simulated altitude of ~3600 m; end-exercise pulse oxygen saturation: ~84%) environments. Running distance was lower (P < 0.05) in HOT compared to CON and HYP for the first sprint but larger (P < 0.05) sprint decrement score occurred in HYP versus HOT and CON. Compared to CON, the cumulated distance covered over the five sprints was lower (P < 0.01) in HYP but not in HOT. Irrespective of the environmental condition, significant changes occurred from the first to the fifth sprint repetitions (all three conditions compounded) in selected running kinetics (mean horizontal forces, P < 0.01) or kinematics (contact and swing times, both P < 0.001; step frequency, P < 0.001) and spring-mass characteristics (vertical stiffness, P < 0.001; leg stiffness, P < 0.01). No significant interaction between sprint number and condition was found for any mechanical data. Preliminary evidence indicates that repeated-sprint ability is more impaired in hypoxia than in a hot environment, when compared to a control condition. However, as sprints are repeated, mechanical alterations appear not to be exacerbated in severe (heat, hypoxia) environmental conditions.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Emprechtinger, M.; Lis, D. C.; Monje, R. R.
2013-03-01
We present Herschel/HIFI observations of 30 transitions of water isotopologues toward the high-mass star-forming region NGC 6334 I. The line profiles of H{sup 16} {sub 2}O, H{sup 17} {sub 2}O, H{sup 18} {sub 2}O, and HDO show a complex pattern of emission and absorption components associated with the embedded hot cores, a lower-density envelope, two outflow components, and several foreground clouds, some associated with the NGC 6334 complex, others seen in projection against the strong continuum background of the source. Our analysis reveals an H{sub 2}O ortho/para ratio of 3 {+-} 0.5 in the foreground clouds, as well as themore » outflow. The water abundance varies from {approx}10{sup -8} in the foreground clouds and the outer envelope to {approx}10{sup -6} in the hot core. The hot core abundance is two orders of magnitude below the chemical model predictions for dense, warm gas, but within the range of values found in other Herschel/HIFI studies of hot cores and hot corinos. This may be related to the relatively low gas and dust temperature ({approx}100 K), or time-dependent effects, resulting in a significant fraction of water molecules still locked up in dust grain mantles. The HDO/H{sub 2}O ratio in NGC 6334 I, {approx}2 Multiplication-Sign 10{sup -4}, is also relatively low, but within the range found in other high-mass star-forming regions.« less
NASA Astrophysics Data System (ADS)
Walsh, C. A.; Chittenden, J. P.; McGlinchey, K.; Niasse, N. P. L.; Appelbe, B. D.
2017-04-01
Three-dimensional extended-magnetohydrodynamic simulations of the stagnation phase of inertial confinement fusion implosion experiments at the National Ignition Facility are presented, showing self-generated magnetic fields over 104 T . Angular high mode-number perturbations develop large magnetic fields, but are localized to the cold, dense hot-spot surface, which is hard to magnetize. When low-mode perturbations are also present, the magnetic fields are injected into the hot core, reaching significant magnetizations, with peak local thermal conductivity reductions greater than 90%. However, Righi-Leduc heat transport effectively cools the hot spot and lowers the neutron spectra-inferred ion temperatures compared to the unmagnetized case. The Nernst effect qualitatively changes the results by demagnetizing the hot-spot core, while increasing magnetizations at the edge and near regions of large heat loss.
Walsh, C A; Chittenden, J P; McGlinchey, K; Niasse, N P L; Appelbe, B D
2017-04-14
Three-dimensional extended-magnetohydrodynamic simulations of the stagnation phase of inertial confinement fusion implosion experiments at the National Ignition Facility are presented, showing self-generated magnetic fields over 10^{4} T. Angular high mode-number perturbations develop large magnetic fields, but are localized to the cold, dense hot-spot surface, which is hard to magnetize. When low-mode perturbations are also present, the magnetic fields are injected into the hot core, reaching significant magnetizations, with peak local thermal conductivity reductions greater than 90%. However, Righi-Leduc heat transport effectively cools the hot spot and lowers the neutron spectra-inferred ion temperatures compared to the unmagnetized case. The Nernst effect qualitatively changes the results by demagnetizing the hot-spot core, while increasing magnetizations at the edge and near regions of large heat loss.
HOT PLASMA FROM SOLAR ACTIVE REGION CORES: A TEST OF AC AND DC CORONAL HEATING MODELS?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schmelz, J. T.; Christian, G. M.; Dhaliwal, R. S.
2015-06-20
Direct current (DC) models of solar coronal heating invoke magnetic reconnection to convert magnetic free energy into heat, whereas alternating current (AC) models invoke wave dissipation. In both cases the energy is supplied by photospheric footpoint motions. For a given footpoint velocity amplitude, DC models predict lower average heating rates but greater temperature variability when compared to AC models. Therefore, evidence of hot plasma (T > 5 MK) in the cores of active regions could be one of the ways for current observations to distinguish between AC and DC models. We have analyzed data from the X-Ray Telescope (XRT) andmore » the Atmospheric Imaging Assembly for 12 quiescent active region cores, all of which were observed in the XRT Be-thick channel. We did Differential Emission Measure (DEM) analysis and achieved good fits for each data set. We then artificially truncated the hot plasma of the DEM model at 5 MK and examined the resulting fits to the data. For some regions in our sample, the XRT intensities continued to be well-matched by the DEM predictions, even without the hot plasma. This truncation, however, resulted in unacceptable fits for the other regions. This result indicates that the hot plasma is present in these regions, even if the precise DEM distribution cannot be determined with the data available. We conclude that reconnection may be heating the hot plasma component of these active regions.« less
NASA Astrophysics Data System (ADS)
Pillans, Luke; Harmer, Jack; Edwards, Tim; Richardson, Lee
2016-05-01
Geolocation is the process of calculating a target position based on bearing and range relative to the known location of the observer. A high performance thermal imager with integrated geolocation functions is a powerful long range targeting device. Firefly is a software defined camera core incorporating a system-on-a-chip processor running the AndroidTM operating system. The processor has a range of industry standard serial interfaces which were used to interface to peripheral devices including a laser rangefinder and a digital magnetic compass. The core has built in Global Positioning System (GPS) which provides the third variable required for geolocation. The graphical capability of Firefly allowed flexibility in the design of the man-machine interface (MMI), so the finished system can give access to extensive functionality without appearing cumbersome or over-complicated to the user. This paper covers both the hardware and software design of the system, including how the camera core influenced the selection of peripheral hardware, and the MMI design process which incorporated user feedback at various stages.
Demonstration of pharmaceutical tablet coating process by injection molding technology.
Puri, Vibha; Brancazio, David; Harinath, Eranda; Martinez, Alexander R; Desai, Parind M; Jensen, Keith D; Chun, Jung-Hoon; Braatz, Richard D; Myerson, Allan S; Trout, Bernhardt L
2018-01-15
We demonstrate the coating of tablets using an injection molding (IM) process that has advantage of being solvent free and can provide precision coat features. The selected core tablets comprising 10% w/w griseofulvin were prepared by an integrated hot melt extrusion-injection molding (HME-IM) process. Coating trials were conducted on a vertical injection mold machine. Polyethylene glycol and polyethylene oxide based hot melt extruded coat compositions were used. Tablet coating process feasibility was successfully demonstrated using different coating mold designs (with both overlapping and non-overlapping coatings at the weld) and coat thicknesses of 150 and 300 μm. The resultant coated tablets had acceptable appearance, seal at the weld, and immediate drug release profile (with an acceptable lag time). Since IM is a continuous process, this study opens opportunities to develop HME-IM continuous processes for transforming powder to coated tablets. Copyright © 2017 Elsevier B.V. All rights reserved.
How Do Earth-Sized, Short-Period Planets Form?
NASA Astrophysics Data System (ADS)
Kohler, Susanna
2017-08-01
Matching theory to observation often requires creative detective work. In a new study, scientists have used a clever test to reveal clues about the birth of speedy, Earth-sized planets.Former Hot Jupiters?Artists impression of a hot Jupiter with an evaporating atmosphere. [NASA/Ames/JPL-Caltech]Among the many different types of exoplanets weve observed, one unusual category is that of ultra-short-period planets. These roughly Earth-sized planets speed around their host stars at incredible rates, with periods of less than a day.How do planets in this odd category form? One popular theory is that they were previously hot Jupiters, especially massive gas giants orbiting very close to their host stars. The close orbit caused the planets atmospheres to be stripped away, leaving behind only their dense cores.In a new study, a team of astronomers led by Joshua Winn (Princeton University) has found a clever way to test this theory.Planetary radius vs. orbital period for the authors three statistical samples (colored markers) and the broader sample of stars in the California Kepler Survey. [Winn et al. 2017]Testing MetallicitiesStars hosting hot Jupiters have an interesting quirk: they typically have metallicities that are significantly higher than an average planet-hosting star. It is speculated that this is because planets are born from the same materials as their host stars, and hot Jupiters require the presence of more metals to be able to form.Regardless of the cause of this trend, if ultra-short-period planets are in fact the solid cores of former hot Jupiters, then the two categories of planets should have hosts with the same metallicity distributions. The ultra-short-period-planet hosts should therefore also be weighted to higher metallicities than average planet-hosting stars.To test this, the authors make spectroscopic measurements and gather data for a sample of stellar hosts split into three categories:64 ultra-short-period planets (orbital period shorter than a day)23 hot Jupiters (larger than 4 times Earths radius and orbital period shorter than 10 days)243 small hot planets (smaller than 4 times Earths radius and orbital period between 1 and 10 days)They then compare the metallicity distributions of these three groups.Back to the Drawing BoardMetallicity distributions of the three statistical samples. The hot-Jupiter hosts (orange) have different distribution than the others; it is weighted more toward higher metallicities. [Winn et al. 2017]Winn and collaborators find that hosts of ultra-short-period planets do not have the same metallicity distribution as hot-Jupiter hosts; the metallicities of hot-Jupiter hosts are significantly higher. The metallicity distributions for hosts of ultra-short-period planets and hosts of small hot planets were statistically indistinguishable, however.These results strongly suggest that the majority of ultra-short-period planets are not the cores of former hot Jupiters. Alternative options include the possibility that they are the cores of smaller planets, such as sub-Neptunes, or that they are the short-period extension of the distribution of close-in, small rocky planets that formed by core accretion.This narrowing of the options for the formation of ultra-short-period planets is certainly intriguing. We can hope to further explore possibilities in the future after the Transiting Exoplanet Survey Satellites (TESS) comes online next year; TESS is expected to discover many more ultra-short-period planets that are too faint for Kepler to detect.CitationJoshua N. Winn et al 2017 AJ 154 60. doi:10.3847/1538-3881/aa7b7c
Is What's Hot in Reading What Should Be Important for Reading Instruction?
ERIC Educational Resources Information Center
Rasinski, Timothy
2016-01-01
For years one of the most anticipated events in reading instruction has been Jack Cassidy and his colleagues' annual publication of the "What's Hot, What's Not" survey. In their present study, using longitudinal data from the What's Hot survey, Cassidy, Ortlieb, and Grote-Garcia (2016) make the case that because the Common Core Standards…
Deception of ambient and body core temperature improves self paced cycling in hot, humid conditions.
Castle, Paul C; Maxwell, Neil; Allchorn, Alan; Mauger, Alexis R; White, Danny K
2012-01-01
We used incorrect visual feedback of ambient and core temperature in the heat to test the hypothesis that deception would alleviate the decrement in cycling performance compared to a no deception trial. Seven males completed three 30 min cycling time trials in a randomised order on a Kingcycle ergometer. One time trial was in temperate, control conditions (CON: 21.8 ± 0.6°C; 43.3 ± 4.3%rh), the others in hot, humid conditions (HOT: 31.4 ± 0.3°C; 63.9 ± 4.5%rh). In one of the hot, humid conditions (31.6 ± 0.5°C; 65.4 ± 4.3%rh), participants were deceived (DEC) into thinking the ambient conditions were 26.0°C; 60.0%rh and their core temperature was 0.3°C lower than it really was. Compared to CON (16.63 ± 2.43 km) distance covered was lower in HOT (15.88 ± 2.75 km; P < 0.05), but DEC ameliorated this (16.74 ± 2.87 km; P < 0.05). Mean power output was greater in DEC (184.4 ± 60.4 W) than HOT (168.1 ± 54.1 W; P < 0.05) and no difference was observed between CON and DEC. Rectal temperature and iEMG of the vastus lateralis were not different, but RPE in the third minute was lower in DEC than HOT (P < 0.05). Deception improved performance in the heat by creating a lower RPE, evidence of a subtle mismatch between the subconscious expectation and conscious perception of the task demands.
A high-resolution study of complex organic molecules in hot cores
NASA Astrophysics Data System (ADS)
Calcutt, Hannah; Viti, Serena; Codella, Claudio; Beltrán, Maria T.; Fontani, Francesco; Woods, Paul M.
2014-10-01
We present the results of a line identification analysis using data from the IRAM Plateau de Bure Plateau de Bure Interferometer, focusing on six massive star-forming hot cores: G31.41+0.31, G29.96-0.02, G19.61-0.23, G10.62-0.38, G24.78+0.08A1 and G24.78+0.08A2. We identify several transitions of vibrationally excited methyl formate (HCOOCH3) for the first time in these objects as well as transitions of other complex molecules, including ethyl cyanide (C2H5CN), and isocyanic acid (HNCO). We also postulate a detection of one transition of glycolaldehyde (CH2(OH)CHO) in two new hot cores. We find G29.96-0.02, G19.61-0.23, G24.78+0.08A1 and G24.78+0.08A2 to be chemically very similar. G31.41+0.31, however, is chemically different: it manifests a larger chemical inventory and has significantly larger column densities. We suggest that it may represent a different evolutionary stage to the other hot cores in the sample, or it may surround a star with a higher mass. We derive column densities for methyl formate in G31.41+0.31, using the rotation diagram method, of 4 × 1017 cm-2 and a Trot of ˜170 K. For G29.96-0.02, G24.78+0.08A1 and G24.78+0.08A2, glycolaldehyde, methyl formate and methyl cyanide, all seem to trace the same material and peak at roughly the same position towards the dust emission peak. For G31.41+0.31, however, glycolaldehyde shows a different distribution to methyl formate and methyl cyanide and seems to trace the densest, most compact inner part of hot cores.
Preparation of acetaminophen capsules containing beads prepared by hot-melt direct blend coating.
Pham, Loan; Christensen, John M
2014-02-01
Twelve hydrophobic coating agents were assessed for their effects on drug release after coating sugar cores by a flexible hot-melt coating method using direct blending. Drug-containing pellets were also produced and used as cores. The cores were coated with single or double wax layers containing acetaminophen (APAP). The harder the wax, the slower the resultant drug releases from single-coated beads. Wax coating can be deposited on cores up to 28% of the beads final weight and reaching 58% with wax and drug. Carnauba-coated beads dissolved in approximately 6 h releasing 80% of the loaded drug. Applying another wax layer extended drug release over 20 h, while still delivering 80% of the loaded drug. When drug-containing pellets (33-58% drug loading) were used as cores, double wax-coated pellets exhibited a near zero-order drug release for 16 h, releasing 80% of the loaded drug delivering 18 mg/h. The simple process of hot-melt coating by direct blending of pellet-containing drug-coated formulations provides excellent options for immediate and sustained release formulations when higher lipid coating or drug loading is warranted. Predicted plasma drug concentration time profiles using convolution and in vitro drug release properties of the beads were performed for optimal formulations.
Human behavioral thermoregulation during exercise in the heat.
Flouris, A D; Schlader, Z J
2015-06-01
The human capacity to perform prolonged exercise is impaired in hot environments. To address this issue, a number of studies have investigated behavioral aspects of thermoregulation that are recognized as important factors in determining performance. In this review, we evaluated and interpreted the available knowledge regarding the voluntary control of exercise work rate in hot environments. Our analysis indicated that: (a) Voluntary reductions in exercise work rate in uncompensable heat aid thermoregulation and are, therefore, thermoregulatory behaviors. (b) Unlike thermal behavior during rest, the role of thermal comfort as the ultimate mediator of thermal behavior during exercise in the heat remains uncertain. By contrast, the rating of perceived exertion appears to be the key perceptual controller under such conditions, with thermal perception playing a more modulatory role. (c) Prior to increases in core temperature (when only skin temperature is elevated), reductions in self-selected exercise work rate in the heat are likely mediated by thermal perception (thermal comfort and sensation) and its influence on the rating of perceived exertion. (d) However, when both core and skin temperatures are elevated, factors associated with cardiovascular strain likely dictate the rate of perceived exertion response, thereby mediating such voluntary reductions in exercise work rate. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Kavanagh, Kylie; Davis, Ashely T; Jenkins, Kurt A; Flynn, D Mickey
2016-07-01
Increasing heat shock protein 70 (HSP70) in aged and/or insulin-resistant animal models confers benefits to healthspan and lifespan. Heat application to increase core temperature induces HSPs in metabolically important tissues, and preliminary human and animal data suggest that heated hydrotherapy is an effective method to achieve increased HSPs. However, safety concerns exist, particularly in geriatric medicine where organ and cardiovascular disease commonly will preexist. We evaluated young vervet monkeys compared to old, insulin-resistant vervet monkeys (Chlorocebus aethiops sabaeus) in their core temperatures, glucose tolerance, muscle HSP70 level, and selected safety biomarkers after 10 sessions of hot water immersions administered twice weekly. Hot water immersion robustly induced the heat shock response in muscles. We observed that heat-treated old and young monkeys have significantly higher muscle HSP70 than control monkeys and treatment was without significant adverse effects on organ or cardiovascular health. Heat therapy improved pancreatic responses to glucose challenge and tended to normalize glucose excursions. A trend for worsened blood pressure and glucose values in the control monkeys and improved values in heat-treated monkeys were seen to support further investigation into the safety and efficacy of this intervention for metabolic syndrome or diabetes in young or old persons unable to exercise.
Distinct Rayleigh scattering from hot spot mutant p53 proteins reveals cancer cells.
Jun, Ho Joon; Nguyen, Anh H; Kim, Yeul Hong; Park, Kyong Hwa; Kim, Doyoun; Kim, Kyeong Kyu; Sim, Sang Jun
2014-07-23
The scattering of light redirects and resonances when an electromagnetic wave interacts with electrons orbits in the hot spot core protein and oscillated electron of the gold nanoparticles (AuNP). This report demonstrates convincingly that resonant Rayleigh scattering generated from hot spot mutant p53 proteins is correspondence to cancer cells. Hot spot mutants have unique local electron density changes that affect specificity of DNA binding affinity compared with wild types. Rayleigh scattering changes introduced by hot-spot mutations were monitored by localized surface plasmon resonance (LSPR) shift changes. The LSPR λmax shift for hot-spot mutants ranged from 1.7 to 4.2 nm for mouse samples and from 0.64 nm to 2.66 nm for human samples, compared to 9.6 nm and 15 nm for wild type and mouse and human proteins, respectively with a detection sensitivity of p53 concentration at 17.9 nM. It is interesting that hot-spot mutants, which affect only interaction with DNA, launches affinitive changes as considerable as wild types. These changes propose that hot-spot mutants p53 proteins can be easily detected by local electron density alterations that disturbs the specificity of DNA binding of p53 core domain on the surface of the DNA probed-nanoplasmonic sensor. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
NASA Astrophysics Data System (ADS)
Zhang, Li; Wu, Bao-lin; Liu, Yu-lin
2017-12-01
An Al-based composite reinforced with core-shell-structured Ti/Al3Ti was fabricated through a powder metallurgy route followed by hot extrusion and was found to exhibit promising mechanical properties. The ultimate tensile strength and elongation of the composite sintered at 620°C for 5 h and extruded at a mass ratio of 12.75:1 reached 304 MPa and 14%, respectively, and its compressive deformation reached 60%. The promising mechanical properties are due to the core-shell-structured reinforcement, which is mainly composed of Al3Ti and Ti and is bonded strongly with the Al matrix, and to the reduced crack sensitivity of Al3Ti. The refined grains after hot extrusion also contribute to the mechanical properties of this composite. The mechanical properties might be further improved through regulating the relative thickness of Al-Ti intermetallics and Ti metal layers by adjusting the sintering time and the subsequent extrusion process.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Epstein, R.; Goncharov, V. N.; Marshall, F. J.
Pressure, by definition, characterizes the conditions within an isobaric implosion core at peak compression [Gus'kov et al., Nucl. Fusion 16, 957 (1976); Betti et al., Phys. Plasmas 8, 5257 (2001)] and is a key parameter in quantifying its near-ignition performance [Lawson, Proc. Phys. Soc. London, B 70, 6 (1957); Betti et al., Phys. Plasmas 17, 058102 (2010); Goncharov et al., Phys. Plasmas 21, 056315 (2014); and Glenzer et al., Phys. Plasmas 19, 056318 (2012)]. At high spectral energy, where the x-ray emission from an imploded hydrogen core is optically thin, the emissivity profile can be inferred from the spatially resolvedmore » core emission. This emissivity, which can be modeled accurately under hot-core conditions, is dependent almost entirely on the pressure when measured within a restricted spectral range matched to the temperature range anticipated for the emitting volume. In this way, the hot core pressure at the time of peak emission can be inferred from the measured free-free emissivity profile. The pressure and temperature dependences of the x-ray emissivity and the neutron-production rate explain a simple scaling of the total filtered x-ray emission as a constant power of the total neutron yield for implosions of targets of similar design over a broad range of shell implosion isentropes. This scaling behavior has been seen in implosion simulations and is confirmed by measurements of high-isentrope implosions [Sangster et al., Phys. Plasmas 20, 056317 (2013)] on the OMEGA laser system [Boehly et al., Opt. Commun. 133, 495 (1997)]. Attributing the excess emission from less-stable, low-isentrope implosions, above the level expected from this neutron-yield scaling, to the higher emissivity of shell carbon mixed into the implosion's central hot spot, the hot-spot “fuel–shell” mix mass can be inferred.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Epstein, R.; Goncharov, V. N.; Marshall, F. J.
Pressure, by definition, characterizes the conditions within an isobaric implosion core at peak compression [Gus’kov et al., Nucl. Fusion 16, 957 (1976); Betti et al., Phys. Plasmas 8, 5257 (2001)] and is a key parameter in quantifying its near-ignition performance [Lawson, Proc. Phys. Soc. London, B 70, 6 (1957); Betti et al., Phys. Plasmas 17, 058102 (2010); Goncharov et al., Phys. Plasmas 21, 056315 (2014); and Glenzer et al., Phys. Plasmas 19, 056318 (2012)]. At high spectral energy, where the x-ray emission from an imploded hydrogen core is optically thin, the emissivity profile can be inferred from the spatially resolvedmore » core emission. This emissivity, which can be modeled accurately under hot-core conditions, is dependent almost entirely on the pressure when measured within a restricted spectral range matched to the temperature range anticipated for the emitting volume. In this way, the hot core pressure at the time of peak emission can be inferred from the measured free-free emissivity profile. The pressure and temperature dependences of the x-ray emissivity and the neutron-production rate explain a simple scaling of the total filtered x-ray emission as a constant power of the total neutron yield for implosions of targets of similar design over a broad range of shell implosion isentropes. This scaling behavior has been seen in implosion simulations and is confirmed by measurements of high-isentrope implosions [Sangster et al., Phys. Plasmas 20, 056317 (2013)] on the OMEGA laser system [Boehly et al., Opt. Commun. 133, 495 (1997)]. Attributing the excess emission from less-stable, low-isentrope implosions, above the level expected from this neutron-yield scaling, to the higher emissivity of shell carbon mixed into the implosion’s central hot spot, the hot-spot “fuel–shell” mix mass can be inferred.« less
The Role of the Common Core in the Gubernatorial Elections of 2014
ERIC Educational Resources Information Center
Supovitz, Jonathan; Newman, Bobbi; Smith, Ariel
2014-01-01
After the Spring 2014 primaries, the Common Core State Standards were viewed as a political hot potato. As former Arkansas Governor Mike Huckabee said, "the Common Core has become toxic, I think it's radioactive…It has become an incredibly controversial topic on both the left and the right." Even so, the Common Core turned out to play a…
Long-period seismology on Europa: 1. Physically consistent interior models
NASA Astrophysics Data System (ADS)
Cammarano, F.; Lekic, V.; Manga, M.; Panning, M.; Romanowicz, B.
2006-12-01
In order to examine the potential of seismology to determine the interior structure and properties of Europa, it is essential to calculate seismic velocities and attenuation for the range of plausible interiors. We calculate a range of models for the physical structure of Europa, as constrained by the satellite's composition, mass, and moment of inertia. We assume a water-ice shell, a pyrolitic or a chondritic mantle, and a core composed of pure iron or iron plus 20 weight percent of sulfur. We consider two extreme mantle thermal states: hot and cold. Given a temperature and composition, we determine density, seismic velocities, and attenuation using thermodynamical models. While anelastic effects will be negligible in a cold mantle and the brittle part of the ice shell, strong dispersion and dissipation are expected in a hot convective mantle and the bulk of the ice shell. There is a strong relationship between different thermal structures and compositions. The ``hot'' mantle may maintain temperatures consistent with a liquid core made of iron plus light elements. For the ``cold scenarios,'' the possibility of a solid iron core cannot be excluded, and it may even be favored. The depths of the ocean and core-mantle boundary are determined with high precision, 10 km and 40 km, respectively, once we assume a composition and thermal structure. Furthermore, the depth of the ocean is relatively insensitive (4 km) to the core composition used.
Vaporizing particle velocimeter
NASA Technical Reports Server (NTRS)
Weinstein, Leonard M. (Inventor)
1992-01-01
A velocimeter measures flow characteristics of a flow traveling through a chamber in a given direction. Tracer particles are entrained in the flow and a source of radiant energy produces an output stream directed transversely to the chamber, having a sufficient intensity to vaporize the particles as they pass through the output stream. Each of the vaporized particles explodes to produce a shock wave and a hot core, and a flow visualization system tracks the motion of the hot cores and shock waves to measure the velocity of each tracer particle and the temperature of the flow around the tracer.
Absence of a Metallicity Effect for Ultra-short-period Planets
NASA Astrophysics Data System (ADS)
Winn, Joshua N.; Sanchis-Ojeda, Roberto; Rogers, Leslie; Petigura, Erik A.; Howard, Andrew W.; Isaacson, Howard; Marcy, Geoffrey W.; Schlaufman, Kevin C.; Cargile, Phillip; Hebb, Leslie
2017-08-01
Ultra-short-period (USP) planets are a newly recognized class of planets with periods shorter than one day and radii smaller than about 2 R ⊕. It has been proposed that USP planets are the solid cores of hot Jupiters that have lost their gaseous envelopes due to photo-evaporation or Roche lobe overflow. We test this hypothesis by asking whether USP planets are associated with metal-rich stars, as has long been observed for hot Jupiters. We find the metallicity distributions of USP-planet and hot-Jupiter hosts to be significantly different (p = 3 × 10-4) based on Keck spectroscopy of Kepler stars. Evidently, the sample of USP planets is not dominated by the evaporated cores of hot Jupiters. The metallicity distribution of stars with USP planets is indistinguishable from that of stars with short-period planets with sizes between 2 and 4 R ⊕. Thus, it remains possible that the USP planets are the solid cores of formerly gaseous planets that are smaller than Neptune. Based on observations obtained at the W. M. Keck Observatory, which is operated jointly by the University of California and the California Institute of Technology. Keck time was granted by NASA, the University of California, the California Institute of Technology, and the University of Hawaii.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Testa, Paola; Reale, Fabio, E-mail: ptesta@cfa.harvard.edu
2012-05-01
We use coronal imaging observations with the Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA), and Hinode/Extreme-ultraviolet Imaging Spectrometer (EIS) spectral data to explore the potential of narrowband EUV imaging data for diagnosing the presence of hot (T {approx}> 5 MK) coronal plasma in active regions. We analyze observations of two active regions (AR 11281, AR 11289) with simultaneous AIA imaging and EIS spectral data, including the Ca XVII line (at 192.8 A), which is one of the few lines in the EIS spectral bands sensitive to hot coronal plasma even outside flares. After careful co-alignment of the imaging and spectral data,more » we compare the morphology in a three-color image combining the 171, 335, and 94 A AIA spectral bands, with the image obtained for Ca XVII emission from the analysis of EIS spectra. We find that in the selected active regions the Ca XVII emission is strong only in very limited areas, showing striking similarities with the features bright in the 94 A (and 335 A) AIA channels and weak in the 171 A band. We conclude that AIA imaging observations of the solar corona can be used to track hot plasma (6-8 MK), and so to study its spatial variability and temporal evolution at high spatial and temporal resolution.« less
Occupational heat strain in a hot underground metal mine.
Lutz, Eric A; Reed, Rustin J; Turner, Dylan; Littau, Sally R
2014-04-01
In a hot underground metal mine, this study evaluated the relationship between job task, physical body type, work shift, and heat strain. Thirty-one miners were evaluated during 98 shifts while performing deep shaft-sinking tasks. Continuous core body temperature, heart rate, pre- and postshift urine specific gravity (USG), and body mass index were measured. Cutting and welding tasks were associated with significantly (P < 0.05) increased core body temperature, maximum heart rate, and increased postshift urine specific gravity. Miners in the obese level II and III body mass index categories, as well as those working night shift, had lower core body temperatures (P < 0.05). This study confirms that job task, body type, and shift are risk factors for heat strain.
DOT National Transportation Integrated Search
2006-01-01
This project evaluated the procedures proposed by the Mechanistic-Empirical Pavement Design Guide (MEPDG) to characterize existing hot-mix asphalt (HMA) layers for rehabilitation purposes. Thirty-three cores were extracted from nine sites in Virginia...
Firefly: A HOT camera core for thermal imagers with enhanced functionality
NASA Astrophysics Data System (ADS)
Pillans, Luke; Harmer, Jack; Edwards, Tim
2015-06-01
Raising the operating temperature of mercury cadmium telluride infrared detectors from 80K to above 160K creates new applications for high performance infrared imagers by vastly reducing the size, weight and power consumption of the integrated cryogenic cooler. Realizing the benefits of Higher Operating Temperature (HOT) requires a new kind of infrared camera core with the flexibility to address emerging applications in handheld, weapon mounted and UAV markets. This paper discusses the Firefly core developed to address these needs by Selex ES in Southampton UK. Firefly represents a fundamental redesign of the infrared signal chain reducing power consumption and providing compatibility with low cost, low power Commercial Off-The-Shelf (COTS) computing technology. This paper describes key innovations in this signal chain: a ROIC purpose built to minimize power consumption in the proximity electronics, GPU based image processing of infrared video, and a software customisable infrared core which can communicate wirelessly with other Battlespace systems.
Short-term hot-hardness characteristics of five case hardened steels
NASA Technical Reports Server (NTRS)
Anderson, N. E.; Zaretsky, E. V.
1975-01-01
Short-term hot-hardness studies were performed with carburized and hardened AISI 8620, CBS 1000, CBS 1000M, CBS 600, and Vasco X-2 steels. Case and core hardness measurements were made at temperatures from 294 to 811 K (70 to 1000 F). The data were compared with data for high-speed tool steels and AISI 52100. The materials tested can be ranked as follows in order of decreasing hot-hardness retention: (1) Vasco X-2; equivalent to through-hardened tool steels up to 644 K (700 F) above which Vasco X-2 is inferior; (2) CBS 1000, (3) CBS 1000M; (4) CBS 6000; better hardness retention at elevated temperatures than through-hardened AISI 52100; and (5) AISI 8620. For the carburized steels, the change in hardness with temperature of the case and core are similar for a given material. The short-term hot hardness of these materials can be predicted with + or - 1 point Rockwell C.
Benson, L.V.; Smoot, J.P.; Kashgarian, Michaele; Sarna-Wojcicki, A.; Burdett, J.W.
1997-01-01
Uncalibrated radiocarbon data from core PLC92B taken from Wizards Cove in the Pyramid Lake subbasin indicate that the Trego Hot Springs and Wono tephra layers were deposited 23,200 ?? 300 and 27,300 ??300 14C yr B.P. (uncorrected for reservoir effect). Sedimentological data from sites in the Pyramid Lake and Smoke Creek-Black Rock Desert subbasins indicate that the Trego Hot Springs tephra layer was deposited during a relatively dry period when Pyramid Lake was at or below its spill point (1177 m) to the Winnemucca Lake subbasin. The Wono tephra layer was deposited when lake depth was controlled by spill across Emerson Pass sill (1207 m) to the Smoke Creek-Black Rock Desert subbasin. 18O data from core PLC92B also support the concept that the Trego Hot Springs tephra fell into a relatively shallow Pyramid Lake and that the Wono tephra fell into a deeper spilling lake. ?? 1997 University of Washington.
Kimura, Hiroyuki; Ishibashi, Jun-Ichiro; Masuda, Harue; Kato, Kenji; Hanada, Satoshi
2007-04-01
International drilling projects for the study of microbial communities in the deep-subsurface hot biosphere have been expanded. Core samples obtained by deep drilling are commonly contaminated with mesophilic microorganisms in the drilling fluid, making it difficult to examine the microbial community by 16S rRNA gene clone library analysis. To eliminate mesophilic organism contamination, we previously developed a new method (selective phylogenetic analysis [SePA]) based on the strong correlation between the guanine-plus-cytosine (G+C) contents of the 16S rRNA genes and the optimal growth temperatures of prokaryotes, and we verified the method's effectiveness (H. Kimura, M. Sugihara, K. Kato, and S. Hanada, Appl. Environ. Microbiol. 72:21-27, 2006). In the present study we ascertained SePA's ability to eliminate contamination by archaeal rRNA genes, using deep-sea hydrothermal fluid (117 degrees C) and surface seawater (29.9 degrees C) as substitutes for deep-subsurface geothermal samples and drilling fluid, respectively. Archaeal 16S rRNA gene fragments, PCR amplified from the surface seawater, were denatured at 82 degrees C and completely digested with exonuclease I (Exo I), while gene fragments from the deep-sea hydrothermal fluid remained intact after denaturation at 84 degrees C because of their high G+C contents. An examination using mixtures of DNAs from the two environmental samples showed that denaturation at 84 degrees C and digestion with Exo I completely eliminated archaeal 16S rRNA genes from the surface seawater. Our method was quite useful for culture-independent community analysis of hyperthermophilic archaea in core samples recovered from deep-subsurface geothermal environments.
2015-03-26
INVESTIGATION OF THE HIGH -CYCLE FATIGUE LIFE OF SELECTIVE LASER MELTED AND HOT ISOSTATICALLY PRESSED TI-6AL-4V THESIS Kevin D. Rekedal...ENY-MS-15-M-212 INVESTIGATION OF THE HIGH -CYCLE FATIGUE LIFE OF SELECTIVE LASER MELTED AND HOT ISOSTATICALLY PRESSED TI-6AL-4V THESIS...AFIT-ENY-MS-15-M-212 INVESTIGATION OF THE HIGH -CYCLE FATIGUE LIFE OF SELECTIVE LASER MELTED AND HOT ISOSTATICALLY PRESSED TI-6AL-4V
Swiderska, Zaneta; Korzynska, Anna; Markiewicz, Tomasz; Lorent, Malgorzata; Zak, Jakub; Wesolowska, Anna; Roszkowiak, Lukasz; Slodkowska, Janina; Grala, Bartlomiej
2015-01-01
Background. This paper presents the study concerning hot-spot selection in the assessment of whole slide images of tissue sections collected from meningioma patients. The samples were immunohistochemically stained to determine the Ki-67/MIB-1 proliferation index used for prognosis and treatment planning. Objective. The observer performance was examined by comparing results of the proposed method of automatic hot-spot selection in whole slide images, results of traditional scoring under a microscope, and results of a pathologist's manual hot-spot selection. Methods. The results of scoring the Ki-67 index using optical scoring under a microscope, software for Ki-67 index quantification based on hot spots selected by two pathologists (resp., once and three times), and the same software but on hot spots selected by proposed automatic methods were compared using Kendall's tau-b statistics. Results. Results show intra- and interobserver agreement. The agreement between Ki-67 scoring with manual and automatic hot-spot selection is high, while agreement between Ki-67 index scoring results in whole slide images and traditional microscopic examination is lower. Conclusions. The agreement observed for the three scoring methods shows that automation of area selection is an effective tool in supporting physicians and in increasing the reliability of Ki-67 scoring in meningioma.
Swiderska, Zaneta; Korzynska, Anna; Markiewicz, Tomasz; Lorent, Malgorzata; Zak, Jakub; Wesolowska, Anna; Roszkowiak, Lukasz; Slodkowska, Janina; Grala, Bartlomiej
2015-01-01
Background. This paper presents the study concerning hot-spot selection in the assessment of whole slide images of tissue sections collected from meningioma patients. The samples were immunohistochemically stained to determine the Ki-67/MIB-1 proliferation index used for prognosis and treatment planning. Objective. The observer performance was examined by comparing results of the proposed method of automatic hot-spot selection in whole slide images, results of traditional scoring under a microscope, and results of a pathologist's manual hot-spot selection. Methods. The results of scoring the Ki-67 index using optical scoring under a microscope, software for Ki-67 index quantification based on hot spots selected by two pathologists (resp., once and three times), and the same software but on hot spots selected by proposed automatic methods were compared using Kendall's tau-b statistics. Results. Results show intra- and interobserver agreement. The agreement between Ki-67 scoring with manual and automatic hot-spot selection is high, while agreement between Ki-67 index scoring results in whole slide images and traditional microscopic examination is lower. Conclusions. The agreement observed for the three scoring methods shows that automation of area selection is an effective tool in supporting physicians and in increasing the reliability of Ki-67 scoring in meningioma. PMID:26240787
Space Storable Propellant Performance Gas/Liquid Like-Doublet Injector Characterization
NASA Technical Reports Server (NTRS)
Falk, A. Y.
1972-01-01
A 30-month applied research program was conducted, encompassing an analytical, design, and experimental effort to relate injector design parameters to simultaneous attainment of high performance and component (injector/thrust chamber) compatibility for gas/liquid space-storable propellants. The gas/liquid propellant combination selected for study was FLOX (82.6% F2)/ambient temperature gaseous methane. The injector pattern characterized was the like-(self)-impinging doublet. Program effort was apportioned into four basic technical tasks: injector and thrust chamber design, injector and thrust chamber fabrication, performance evaluation testing, and data evaluation and reporting. Analytical parametric combustion analyses and cold flow distribution and atomization experiments were conducted with injector segment models to support design of injector/thrust chamber combinations for hot fire evaluation. Hot fire tests were conducted to: (1) optimize performance of the injector core elements, and (2) provide design criteria for the outer zone elements so that injector/thrust chamber compatibility could be achieved with only minimal performance losses.
Maloney, Shane K; Fuller, Andrea; Meyer, Leith C R; Kamerman, Peter R; Mitchell, Graham; Mitchell, Duncan
2011-06-01
Using implanted temperature loggers, we measured core body temperature in nine western grey kangaroos every 5 min for 24 to 98 days in spring and summer. Body temperature was highest at night and decreased rapidly early in the morning, reaching a nadir at 10:00 h, after ambient temperature and solar radiation had begun to increase. On hotter days, the minimum morning body temperature was lower than on cooler days, decreasing from a mean of 36.2°C in the spring to 34.0°C in the summer. This effect correlated better with the time of the year than with proximate thermal stressors, suggesting that either season itself or some factor correlated with season, such as food availability, caused the change. Water saving has been proposed as a selective advantage of heterothermy in other large mammals, but in kangaroos the water savings would have been small and not required in a reserve with permanent standing water. We calculate that the lower core temperature could provide energy savings of nearly 7%. It is likely that the heterothermy that we observed on hot days results either from decreased energy intake during the dry season or from a seasonal pattern entrained in the kangaroos that presumably has been selected for because of decreased energy availability during the dry season.
State of the metal core in nanosecond exploding wires and related phenomena
NASA Astrophysics Data System (ADS)
Sarkisov, G. S.; Sasorov, P. V.; Struve, K. W.; McDaniel, D. H.
2004-08-01
Experiments show that an expanding metal wire core that results from a nanosecond electrical explosion in vacuum consists primarily of three different states: solid, microdrop, and gas-plasma. The state of the wire core depends both on the amount of energy deposited before the voltage breakdown and on the heating conditions. For small amounts of deposited energy (on the order of solid-stage enthalpy), the wire core remains in a solid state or is partially disintegrated. For a high level of deposited energy (more than vaporization energy) the wire core is in a gas-plasma state. For an intermediate level of deposited energy (more than melting but less than vaporization), the wire disintegrates into hot liquid microdrops or clusters of submicron size. For a wire core in the cluster state, interferometry demonstrates weak (or even absent) phaseshift. Light emission shows a "firework effect"—the long late-time radiation related to the emission by the expanding cylinder of hot microparticles. For the wire core in a gas-plasma state, interferometry demonstrates a large phaseshift and a fast reduction in light emission due to adiabatic cooling of the expanding wire core. The simulation of this firework effect agrees well with experimental data, assuming submicron size and a temperature approaching boiling for the expanded microparticles cylinder.
UV properties of hot stars in NGC 6752
NASA Technical Reports Server (NTRS)
Altner, Bruce
1990-01-01
The UV properties of hot stars found in the center of NGC 6752 are compared with those outside the core. Few, if any, faint sdB stars are found in the central region, whereas they occur in significant numbers far from the core. A statistically complete photographic survey is used to demonstrate that the faint blue stars in NGC 6752 occur in greater numbers with increasing distance form the center, and the International Ultraviolet Explorer (IUE) findings extend this result all the way to the center of the cluster. A similar phenomenon has been observed optically in other clusters, such as M15.
What's Hot: Texas and the Nation
ERIC Educational Resources Information Center
Cassidy, Jack; Ortlieb, Evan; Grote-Garcia, Stephanie
2016-01-01
For two decades the International Literacy Association (ILA) has published the "What's Hot, What's Not in Literacy Survey." In the last five years, the hottest topics featured on the lists have largely been connected to the English Language Arts Common Core State Standards (ELA CCSS)--a publication produced by the National Governors…
Asbestos and Inconel combined to form hot-gas seal
NASA Technical Reports Server (NTRS)
Wooster, C. W., Jr.
1968-01-01
Hot-gas seal prevents warpage tendencies in large flange joints exposed to high temperatures, such as those present in large space vehicle engine exhausts. Two Inconel wire mesh cores are held in place by an asbestos cloth cover that acts as a spacer to form the seal.
Vincent, Grace E; Ferguson, Sally; Larsen, Brianna; Ridgers, Nicola D; Snow, Rod; Aisbett, Brad
2018-04-06
To examine the effects of sleep restriction on firefighters' physical task performance, physical activity, and physiological and perceived exertion during simulated hot wildfire conditions. 31 firefighters were randomly allocated to either the hot (n = 18, HOT; 33 °C, 8-h sleep opportunity) or hot and sleep restricted (n = 13, HOT + SR; 33 °C, 4-h sleep opportunity) condition. Intermittent, self-paced work circuits of six firefighting tasks were performed for 3 days. Firefighters self-reported ratings of perceived exertion. Heart rate, core temperature, and physical activity were measured continuously. Fluids were consumed ad libitum, and all food and fluids consumed were recorded. Urine volume and urine specific gravity (USG) were analysed and sleep was assessed using polysomnography (PSG). There were no differences between the HOT and HOT + SR groups in firefighters' physical task performance, heart rate, core temperature, USG, or fluid intake. Ratings of perceived exertion were higher (p < 0.05) in the HOT + SR group for two of the six firefighting tasks. The HOT group spent approximately 7 min more undertaking moderate physical activity throughout the 2-h work circuits compared to the HOT + SR group. Two nights of sleep restriction did not influence firefighters' physical task performance or physiological responses during 3 days of simulated wildfire suppression. Further research is needed to explore firefighters' pacing strategies during real wildfire suppression.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brogan, C. L.; Hunter, T. R.; Indebetouw, R.
2016-12-01
We present Very Large Array and Atacama Large Millimeter/submillimeter Array imaging of the deeply embedded protostellar cluster NGC 6334I from 5 cm to 1.3 mm at angular resolutions as fine as 0.″17 (220 au). The dominant hot core MM1 is resolved into seven components at 1.3 mm, clustered within a radius of 1000 au. Four of the components have brightness temperatures >200 K, radii ∼300 au, minimum luminosities ∼10{sup 4} L {sub ⊙}, and must be centrally heated. We term this new phenomenon a “hot multi-core.” Two of these objects also exhibit compact free–free emission at longer wavelengths, consistent withmore » a hypercompact H ii region (MM1B) and a jet (MM1D). The spatial kinematics of the water maser emission centered on MM1D are consistent with it being the origin of the high-velocity bipolar molecular outflow seen in CO. The close proximity of MM1B and MM1D (440 au) suggests a proto-binary or a transient bound system. Several components of MM1 exhibit steep millimeter spectral energy distributions indicative of either unusual dust spectral properties or time variability. In addition to resolving MM1 and the other hot core (MM2) into multiple components, we detect five new millimeter and two new centimeter sources. Water masers are detected for the first time toward MM4A, confirming its membership in the protocluster. With a 1.3 mm brightness temperature of 97 K coupled with a lack of thermal molecular line emission, MM4A appears to be a highly optically thick 240 L {sub ⊙} dust core, possibly tracing a transient stage of massive protostellar evolution. The nature of the strongest water maser source CM2 remains unclear due to its combination of non-thermal radio continuum and lack of dust emission.« less
NASA Astrophysics Data System (ADS)
Brogan, C. L.; Hunter, T. R.; Cyganowski, C. J.; Chandler, C. J.; Friesen, R.; Indebetouw, R.
2016-12-01
We present Very Large Array and Atacama Large Millimeter/submillimeter Array imaging of the deeply embedded protostellar cluster NGC 6334I from 5 cm to 1.3 mm at angular resolutions as fine as 0.″17 (220 au). The dominant hot core MM1 is resolved into seven components at 1.3 mm, clustered within a radius of 1000 au. Four of the components have brightness temperatures >200 K, radii ˜300 au, minimum luminosities ˜104 L ⊙, and must be centrally heated. We term this new phenomenon a “hot multi-core.” Two of these objects also exhibit compact free-free emission at longer wavelengths, consistent with a hypercompact H II region (MM1B) and a jet (MM1D). The spatial kinematics of the water maser emission centered on MM1D are consistent with it being the origin of the high-velocity bipolar molecular outflow seen in CO. The close proximity of MM1B and MM1D (440 au) suggests a proto-binary or a transient bound system. Several components of MM1 exhibit steep millimeter spectral energy distributions indicative of either unusual dust spectral properties or time variability. In addition to resolving MM1 and the other hot core (MM2) into multiple components, we detect five new millimeter and two new centimeter sources. Water masers are detected for the first time toward MM4A, confirming its membership in the protocluster. With a 1.3 mm brightness temperature of 97 K coupled with a lack of thermal molecular line emission, MM4A appears to be a highly optically thick 240 L ⊙ dust core, possibly tracing a transient stage of massive protostellar evolution. The nature of the strongest water maser source CM2 remains unclear due to its combination of non-thermal radio continuum and lack of dust emission.
A Three-phase Chemical Model of Hot Cores: The Formation of Glycine
NASA Astrophysics Data System (ADS)
Garrod, Robin T.
2013-03-01
A new chemical model is presented that simulates fully coupled gas-phase, grain-surface, and bulk-ice chemistry in hot cores. Glycine (NH2CH2COOH), the simplest amino acid, and related molecules such as glycinal, propionic acid, and propanal, are included in the chemical network. Glycine is found to form in moderate abundance within and upon dust-grain ices via three radical-addition mechanisms, with no single mechanism strongly dominant. Glycine production in the ice occurs over temperatures ~40-120 K. Peak gas-phase glycine fractional abundances lie in the range 8 × 10-11-8 × 10-9, occurring at ~200 K, the evaporation temperature of glycine. A gas-phase mechanism for glycine production is tested and found insignificant, even under optimal conditions. A new spectroscopic radiative-transfer model is used, allowing the translation and comparison of the chemical-model results with observations of specific sources. Comparison with the nearby hot-core source NGC 6334 IRS1 shows excellent agreement with integrated line intensities of observed species, including methyl formate. The results for glycine are consistent with the current lack of a detection of this molecule toward other sources; the high evaporation temperature of glycine renders the emission region extremely compact. Glycine detection with ALMA is predicted to be highly plausible, for bright, nearby sources with narrow emission lines. Photodissociation of water and subsequent hydrogen abstraction from organic molecules by OH, and NH2, are crucial to the buildup of complex organic species in the ice. The inclusion of alternative branches within the network of radical-addition reactions appears important to the abundances of hot-core molecules; less favorable branching ratios may remedy the anomalously high abundance of glycolaldehyde predicted by this and previous models.
Planet Traps and Planetary Cores: Origins of the Planet-Metallicity Correlation
NASA Astrophysics Data System (ADS)
Hasegawa, Yasuhiro; Pudritz, Ralph E.
2014-10-01
Massive exoplanets are observed preferentially around high metallicity ([Fe/H]) stars while low-mass exoplanets do not show such an effect. This so-called planet-metallicity correlation generally favors the idea that most observed gas giants at r < 10 AU are formed via a core accretion process. We investigate the origin of this phenomenon using a semi-analytical model, wherein the standard core accretion takes place at planet traps in protostellar disks where rapid type I migrators are halted. We focus on the three major exoplanetary populations—hot Jupiters, exo-Jupiters located at r ~= 1 AU, and the low-mass planets. We show using a statistical approach that the planet-metallicity correlations are well reproduced in these models. We find that there are specific transition metallicities with values [Fe/H] = -0.2 to -0.4, below which the low-mass population dominates, and above which the Jovian populations take over. The exo-Jupiters significantly exceed the hot Jupiter population at all observed metallicities. The low-mass planets formed via the core accretion are insensitive to metallicity, which may account for a large fraction of the observed super-Earths and hot-Neptunes. Finally, a controlling factor in building massive planets is the critical mass of planetary cores (M c, crit) that regulates the onset of rapid gas accretion. Assuming the current data is roughly complete at [Fe/H] > -0.6, our models predict that the most likely value of the "mean" critical core mass of Jovian planets is langM c, critrang ~= 5 M ⊕ rather than 10 M ⊕. This implies that grain opacities in accreting envelopes should be reduced in order to lower M c, crit.
Planet traps and planetary cores: origins of the planet-metallicity correlation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hasegawa, Yasuhiro; Pudritz, Ralph E., E-mail: yasu@asiaa.sinica.edu.tw, E-mail: pudritz@physics.mcmaster.ca
2014-10-10
Massive exoplanets are observed preferentially around high metallicity ([Fe/H]) stars while low-mass exoplanets do not show such an effect. This so-called planet-metallicity correlation generally favors the idea that most observed gas giants at r < 10 AU are formed via a core accretion process. We investigate the origin of this phenomenon using a semi-analytical model, wherein the standard core accretion takes place at planet traps in protostellar disks where rapid type I migrators are halted. We focus on the three major exoplanetary populations—hot Jupiters, exo-Jupiters located at r ≅ 1 AU, and the low-mass planets. We show using a statisticalmore » approach that the planet-metallicity correlations are well reproduced in these models. We find that there are specific transition metallicities with values [Fe/H] = –0.2 to –0.4, below which the low-mass population dominates, and above which the Jovian populations take over. The exo-Jupiters significantly exceed the hot Jupiter population at all observed metallicities. The low-mass planets formed via the core accretion are insensitive to metallicity, which may account for a large fraction of the observed super-Earths and hot-Neptunes. Finally, a controlling factor in building massive planets is the critical mass of planetary cores (M {sub c,} {sub crit}) that regulates the onset of rapid gas accretion. Assuming the current data is roughly complete at [Fe/H] > –0.6, our models predict that the most likely value of the 'mean' critical core mass of Jovian planets is (M {sub c,} {sub crit}) ≅ 5 M {sub ⊕} rather than 10 M {sub ⊕}. This implies that grain opacities in accreting envelopes should be reduced in order to lower M {sub c,} {sub crit}.« less
Park, Jaeyeong; Kim, Jung-Su; Kang, Minju; Sohn, Seok Su; Cho, Won Tae; Kim, Hyoung Seop; Lee, Sunghak
2017-01-01
TWIP-cored three-layer steel sheets were newly fabricated by hot rolling of TWIP steel sheet surrounded by low-carbon (LC) or interstitial-free (IF) steel sheets. TWIP/LC or TWIP/IF interfaces were well bonded without pores or voids, while a few pearlites were thinly formed along the interfaces. The strengths and elongation of the TWIP-cored sheets increased as the volume fraction of TWIP-cored region increased, and were also well matched with the ones calculated by a rule of mixtures based on volume fraction or force fraction. According to digital image correlation and electron back-scatter diffraction analyses, very high strain hardening effect in the initial deformation stage and active twin formation in the interfacial region beneficially affected the overall homogeneous deformation in the TWIP-cored sheets without any yield point phenomenon occurring in the LC sheet and serrations occurring in the TWIP sheet, respectively. These TWIP-cored sheets can cover a wide range of yield strength, tensile strength, and ductility levels, e.g., 320~498 MPa, 545~878 MPa, and 48~54%, respectively, by controlling the volume fraction of TWIP-cored region, and thus present new applications to multi-functional automotive steel sheets requiring excellent properties. PMID:28067318
NASA Astrophysics Data System (ADS)
Park, Jaeyeong; Kim, Jung-Su; Kang, Minju; Sohn, Seok Su; Cho, Won Tae; Kim, Hyoung Seop; Lee, Sunghak
2017-01-01
TWIP-cored three-layer steel sheets were newly fabricated by hot rolling of TWIP steel sheet surrounded by low-carbon (LC) or interstitial-free (IF) steel sheets. TWIP/LC or TWIP/IF interfaces were well bonded without pores or voids, while a few pearlites were thinly formed along the interfaces. The strengths and elongation of the TWIP-cored sheets increased as the volume fraction of TWIP-cored region increased, and were also well matched with the ones calculated by a rule of mixtures based on volume fraction or force fraction. According to digital image correlation and electron back-scatter diffraction analyses, very high strain hardening effect in the initial deformation stage and active twin formation in the interfacial region beneficially affected the overall homogeneous deformation in the TWIP-cored sheets without any yield point phenomenon occurring in the LC sheet and serrations occurring in the TWIP sheet, respectively. These TWIP-cored sheets can cover a wide range of yield strength, tensile strength, and ductility levels, e.g., 320~498 MPa, 545~878 MPa, and 48~54%, respectively, by controlling the volume fraction of TWIP-cored region, and thus present new applications to multi-functional automotive steel sheets requiring excellent properties.
Park, Jaeyeong; Kim, Jung-Su; Kang, Minju; Sohn, Seok Su; Cho, Won Tae; Kim, Hyoung Seop; Lee, Sunghak
2017-01-09
TWIP-cored three-layer steel sheets were newly fabricated by hot rolling of TWIP steel sheet surrounded by low-carbon (LC) or interstitial-free (IF) steel sheets. TWIP/LC or TWIP/IF interfaces were well bonded without pores or voids, while a few pearlites were thinly formed along the interfaces. The strengths and elongation of the TWIP-cored sheets increased as the volume fraction of TWIP-cored region increased, and were also well matched with the ones calculated by a rule of mixtures based on volume fraction or force fraction. According to digital image correlation and electron back-scatter diffraction analyses, very high strain hardening effect in the initial deformation stage and active twin formation in the interfacial region beneficially affected the overall homogeneous deformation in the TWIP-cored sheets without any yield point phenomenon occurring in the LC sheet and serrations occurring in the TWIP sheet, respectively. These TWIP-cored sheets can cover a wide range of yield strength, tensile strength, and ductility levels, e.g., 320~498 MPa, 545~878 MPa, and 48~54%, respectively, by controlling the volume fraction of TWIP-cored region, and thus present new applications to multi-functional automotive steel sheets requiring excellent properties.
Lei, Fan; Kheir, Michael M.; Wang, Xin-Pei; Chai, Yu-Shuang; Yuan, Zhi-Yi; Lu, Xi; Xing, Dong-Ming; Du, Feng; Du, Li-Jun
2013-01-01
The purpose of this study was to assess the effects of berberine (BBR) on thermoregulation in mice exposed to hot (40°C) and cold (4°C) environmental conditions. Four groups of mice were assembled with three different dosages of BBR (0.2, 0.4, and 0.8 mg/kg) and normal saline (control). In room temperature, our largest dosage of BBR (0.8 mg/kg) can reduce rectal temperatures (Tc) of normal mice. In hot conditions, BBR can antagonize the increasing core body temperature and inhibit the expression of HSP70 and TNFα in mice; conversely, in cold conditions, BBR can antagonize the decreasing core body temperature and enhance the expression of TRPM8. This study demonstrates the dual ability of BBR in maintaining thermal balance, which is of great relevance to the regulation of HSP70, TNFα and TRPM8. PMID:23335996
NASA Technical Reports Server (NTRS)
Kemp, N. H.; Root, R. G.; Wu., P. K. S.; Caledonia, G. E.; Pirri, A. N.
1976-01-01
CW laser heated rocket propulsion was investigated in both the flowing core and stationary core configurations. The laser radiation considered was 10.6 micrometers, and the working gas was unseeded hydrogen. The areas investigated included initiation of a hydrogen plasma capable of absorbing laser radiation, the radiation emission properties of hot, ionized hydrogen, the flow of hot hydrogen while absorbing and radiating, the heat losses from the gas and the rocket performance. The stationary core configuration was investigated qualitatively and semi-quantitatively. It was found that the flowing core rockets can have specific impulses between 1,500 and 3,300 sec. They are small devices, whose heating zone is only a millimeter to a few centimeters long, and millimeters to centimeters in radius, for laser power levels varying from 10 to 5,000 kW, and pressure levels of 3 to 10 atm. Heat protection of the walls is a vital necessity, though the fraction of laser power lost to the walls can be as low as 10% for larger powers, making the rockets thermally efficient.
Yant, Howard W.; Stinebiser, Karl W.; Anzur, Gregory C.
1977-01-01
A nuclear reactor, particularly a liquid-metal breeder reactor, whose upper internals include outlet modules for channeling the liquid-metal coolant from selected areas of the outlet of the core vertically to the outlet plenum. The modules are composed of a highly-refractory, high corrosion-resistant alloy, for example, INCONEL-718. Each module is disposed to confine and channel generally vertically the coolant emitted from a subplurality of core-component assemblies. Each module has a grid with openings, each opening disposed to receive the coolant from an assembly of the subplurality. The grid in addition serves as a holdown for the assemblies of the corresponding subplurality preventing their excessive ejection upwardly from the core. In the region directly over the core the outlet modules are of such peripheral form that they nest forming a continuum over the core-component assemblies whose outlet coolant they confine. Each subassembly includes a chimney which confines the coolant emitted by its corresponding subassemblies to generally vertical flow between the outlet of the core and the outlet plenum. Each subplurality of assemblies whose emitted coolant is confined by an outlet module includes assemblies which emit lower-temperature coolant, for example, a control-rod assembly, or fertile assemblies, and assemblies which emit coolant of substantially higher temperature, for example, fuel-rod assemblies. The coolants of different temperatures are mixed in the chimneys reducing the effect of stripping (hot-cold temperature fluctuations) on the remainder of the upper internals which are composed typically of AISI-304 or AISI-316 stainless steel.
ALMA Observations of the IRDC Clump G34.43+00.24 MM3: Complex Organic and Deuterated Molecules
NASA Astrophysics Data System (ADS)
Sakai, Takeshi; Yanagida, Takahiro; Furuya, Kenji; Aikawa, Yuri; Sanhueza, Patricio; Sakai, Nami; Hirota, Tomoya; Jackson, James M.; Yamamoto, Satoshi
2018-04-01
We have observed complex organic molecules (COMs) and deuterated species toward a hot core/corino (HC) associated with the infrared dark cloud clump G34.43+00.24 MM3 with the Atacama Large Millimeter/submillimeter Array. We have detected six normal-COMs (CH3OH, CH3CHO, CH3CH2CN, CH3OCH3, HCOOCH3, and NH2CHO), one deuterated-COM (CH2DCN), and two deuterated fundamental molecules (D2CO and DNC) toward G34.43+00.24 MM3 HC. None of these lines, except for CH3OH, are detected toward the shocked regions in our data, which suggests that COMs do not originate in shocks. The abundance of the COMs relative to CH3OH in G34.43+00.24 MM3 HC is found to be similar to those in high-mass hot cores, rather than those in hot corinos in low-mass star-forming regions. This result suggests that the physical conditions of the warm-up phase of G34.43+00.24 MM3 HC are similar to those of high-mass sources. On the other hand, the D2CO abundance relative to CH3OH in G34.43+00.24 MM3 HC is higher than that of other hot cores, and seems to be comparable to that of hot corinos. The relatively high D2CO/CH3OH ratio of G34.43+00.24 MM3 HC implies a long cold starless phase of G34.43+00.24 MM3 HC.
Sub-mm CO Measurements of the Orion Molecular Cloud
NASA Astrophysics Data System (ADS)
Wilson, T. L.; Muders, D.; Kramer, C.; Henkel, C.
2000-05-01
Images of a >3' region around the Orion KL source have been made in the J=4-3 (461 GHz) and J=7-6 (806 GHz) lines of CO with angular resolutions of 18'' and 13'', using the 10-meter Heinrich Hertz Telescope (HHT) of the Sub-Millimeter Telescope Observatory (SMTO). This region contains a variety of objects: (1) the Hot Core (a region containing complex molecules) and Orion KL outflow (NE of the center of the 10'' diameter Hot Core, and very likely associated with the continuum source `I' (Menten & Reid 1995 ApJ 445, L157)), (2) another outflow source, Orion-S ( ~100'' south of the Hot Core (Rodriguez-Franco et al. 1999 A&A 344, L57)), (3) the ionized-neutral interface at the rear of the Orion HII region, and (4) the Orion Bar feature (an ionized-neutral interface to the SW of the HII region). Regions (3) and (4) are examples of `Photon Dominated Regions' or `PDR's'. The sub-mm CO lines are emitted from warm gas; the J=7-6 line is emitted from an energy level 156 Kelvin above the ground state. The excellent pointing and low sidelobes of the HHT allow accurate comparisons with high r! esolution CO images in lower J lines and images of other species. Our J=7-6 CO image was made with the Harvard-Smithsonian Center for Astrophysics Hot Electron Bolometer (Kawamura et al. 1999 IEEE Trans. on Appl. Superconductivity 9, 3753. The HHT is operated by the Submillimeter Telescope Observatory on behalf of the Max-Planck-Institut f. Radioastronomie and Steward Observatory of The University of Arizona. We thank the CfA receiver group for providing the Hot Electron Bolometer used to take the J=7-6 CO line data.
Summary of reactor plant conditions during L2-2 pre-LOCE maneuver
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tsang, F.Y.; Yarbrough, W.M.; Cannon, J.W.
1979-04-26
This document presents the experimental results obtained during the pre-Loss of Coolant Experiment (LOCE) manuever and the core conditions prior to the L2-2 LOCE. The peak linear heat rate prior to the blowdown was 8.04 kW/ft, the primary coolant mass flow rate was 1.539 Mlbm/hr, the hot leg temperature was 585.9/sup 0/F, and the core ..delta..T was 42/sup 0/F. These conditions satisfied the requirements specified for the L2-2 LOCE except for the hot leg temperature being 12/sup 0/F below the desired 598/sup 0/F.
OSO-8 X-ray spectra of clusters of galaxies. 2: Discussion. [hot intracluster gas structures
NASA Technical Reports Server (NTRS)
Smith, B. W.; Mushotzky, R. F.; Serlemitsos, P. J.
1978-01-01
X-ray spectral parameters obtained from 2 to 20 keV OSO-8 data on X-ray clusters and optical cluster properties were examined to obtain information for restricting models for hot intracluster gas structures. Topics discussed include the radius of the X-ray core in relation to the galaxy core radius, the viral mass of hotter clusters, and galaxy density and optical central cluster properties. A population of cool, dim X-ray clusters which have not been observed is predicted. The iron abundance determinations recently quoted for intracluster gas are uncertain by 50 to greater than 100 percent from this nonstatistical cause alone.
Tamm, Maria; Jakobson, Ainika; Havik, Merle; Burk, Andres; Timpmann, Saima; Allik, Jüri; Oöpik, Vahur; Kreegipuu, Kairi
2014-01-01
The human perception of time was observed under extremely hot conditions. Young healthy men performed a time production task repeatedly in 4 experimental trials in either a temperate (22 °C, relative humidity 35%) or a hot (42 °C, relative humidity 18%) environment and with or without a moderate-intensity treadmill exercise. Within 1 hour, the produced durations indicated a significant compression of short intervals (0.5 to 10 s) in the combination of exercising and high ambient temperature, while neither variable/condition alone was enough to yield the effect. Temporal judgement was analysed in relation to different indicators of arousal, such as critical flicker frequency (CFF), core temperature, heart rate, and subjective ratings of fatigue and exertion. The arousal-sensitive internal clock model (originally proposed by Treisman) is used to explain the temporal compression while exercising in heat. As a result, we suggest that the psychological response to heat stress, the more precisely perceived fatigue, is important in describing the relationship between core temperature and time perception. Temporal compression is related to higher core temperature, but only if a certain level of perceived fatigue is accounted for, implying the existence of a thermoemotional internal clock.
A search for interstellar CH3D: Limits to the methane abundance in Orion-KL
NASA Technical Reports Server (NTRS)
Womack, Maria; Ziurys, L. M.; Apponi, A. J.
1995-01-01
A search has been performed for interstellar CH3D via its J(K) = 1(0) - 0(0) transition at 230 GHz and its J(K) = 2(0) - l(0) and J(K) = 2(1) - 1(1) lines at 465 GHz using the NRAO 12 m and CSO 10 m telescopes towards Orion-KL. This search was done in conjunction with laboratory measurements of all three transitions of CH3D using mm/sub-mm direct absorption spectroscopy. The molecule was not detected down to a 3 sigma level of T(A) less than 0.05 K towards Orion, which suggests an upper limit to the CH3D column density of N less than 6 x 10(exp 18)/sq cm in the hot core region and a fractional abundance (with respect to H2) of less than 6 x 10(exp -6). These measurements suggest that the methane abundance in the Orion hot core is f less than 6 x 10-4, assuming D/H approximately 0.01. Such findings are in agreement with recent hot core chemical models, which suggest CH4/H2 approximately 10(exp -4).
The Detection of Hot Cores and Complex Organic Molecules in the Large Magellanic Cloud
NASA Astrophysics Data System (ADS)
Sewilo, Marta; Indebetouw, Remy; Charnley, Steven; Zahorecz, Sarolta; Oliveira, Joana M.; van Loon, Jacco Th.; Ward, Jacob L.; Chen, C.-H. Rosie; Wiseman, Jennifer; Fukui, Yasuo; Kawamura, Akiko; Meixner, Margaret; Onishi, Toshikazu; Schilke, Peter
2018-01-01
We report the detection of the complex organic molecules (COMs) dimethyl ether (CH3OCH3) and methyl formate (CH3OCHO), and their parent species methanol (CH3OH), toward the N113 star-formation region in the Large Magellanic Cloud (LMC) with the Atacama Large Millimeter/submillimeter Array (ALMA). This constitutes the first detection of CH3OCH3 and CH3OCHO outside the Milky Way. We calculated the rotational temperatures (Trot ~ 130 K) and total column densities (Nrot ~ 1016 cm-2) for two sources in N113 with the COMs detection based on multiple transitions of CH3OH, and measured abundances for all detected species. The physical and chemical properties of these sources, and the association with H2O and OH maser emission indicate that they are hot molecular cores. The fractional abundances of COMs scaled by a factor of 2.5 to account for the lower metallicity in the LMC are comparable to those found at the lower end of the range in Galactic hot cores. Our results have important implications for studies of organic chemistry at higher redshift.
The Detection of Hot Cores and Complex Organic Molecules in the Large Magellanic Cloud
NASA Astrophysics Data System (ADS)
Sewiło, Marta; Indebetouw, Remy; Charnley, Steven B.; Zahorecz, Sarolta; Oliveira, Joana M.; van Loon, Jacco Th.; Ward, Jacob L.; Chen, C.-H. Rosie; Wiseman, Jennifer; Fukui, Yasuo; Kawamura, Akiko; Meixner, Margaret; Onishi, Toshikazu; Schilke, Peter
2018-02-01
We report the first extragalactic detection of the complex organic molecules (COMs) dimethyl ether (CH3OCH3) and methyl formate (CH3OCHO) with the Atacama Large Millimeter/submillimeter Array (ALMA). These COMs, together with their parent species methanol (CH3OH), were detected toward two 1.3 mm continuum sources in the N 113 star-forming region in the low-metallicity Large Magellanic Cloud (LMC). Rotational temperatures ({T}{rot}∼ 130 K) and total column densities ({N}{rot}∼ {10}16 cm‑2) have been calculated for each source based on multiple transitions of CH3OH. We present the ALMA molecular emission maps for COMs and measured abundances for all detected species. The physical and chemical properties of two sources with COMs detection, and the association with H2O and OH maser emission, indicate that they are hot cores. The fractional abundances of COMs scaled by a factor of 2.5 to account for the lower metallicity in the LMC are comparable to those found at the lower end of the range in Galactic hot cores. Our results have important implications for studies of organic chemistry at higher redshift.
Qualification of CASMO5 / SIMULATE-3K against the SPERT-III E-core cold start-up experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Grandi, G.; Moberg, L.
SIMULATE-3K is a three-dimensional kinetic code applicable to LWR Reactivity Initiated Accidents. S3K has been used to calculate several international recognized benchmarks. However, the feedback models in the benchmark exercises are different from the feedback models that SIMULATE-3K uses for LWR reactors. For this reason, it is worth comparing the SIMULATE-3K capabilities for Reactivity Initiated Accidents against kinetic experiments. The Special Power Excursion Reactor Test III was a pressurized-water, nuclear-research facility constructed to analyze the reactor kinetic behavior under initial conditions similar to those of commercial LWRs. The SPERT III E-core resembles a PWR in terms of fuel type, moderator,more » coolant flow rate, and system pressure. The initial test conditions (power, core flow, system pressure, core inlet temperature) are representative of cold start-up, hot start-up, hot standby, and hot full power. The qualification of S3K against the SPERT III E-core measurements is an ongoing work at Studsvik. In this paper, the results for the 30 cold start-up tests are presented. The results show good agreement with the experiments for the reactivity initiated accident main parameters: peak power, energy release and compensated reactivity. Predicted and measured peak powers differ at most by 13%. Measured and predicted reactivity compensations at the time of the peak power differ less than 0.01 $. Predicted and measured energy release differ at most by 13%. All differences are within the experimental uncertainty. (authors)« less
Hot Corrosion of Inconel 625 Overlay Weld Cladding in Smelting Off-Gas Environment
NASA Astrophysics Data System (ADS)
Mohammadi Zahrani, E.; Alfantazi, A. M.
2013-10-01
Degradation mechanisms and hot corrosion behavior of weld overlay alloy 625 were studied. Phase structure, morphology, thermal behavior, and chemical composition of deposited salt mixture on the weld overlay were characterized utilizing XRD, SEM/EDX, DTA, and ICP/OES, respectively. Dilution level of Fe in the weldment, dendritic structure, and degradation mechanisms of the weld were investigated. A molten phase formed on the weld layer at the operating temperature range of the boiler, which led to the hot corrosion attack in the water wall and the ultimate failure. Open circuit potential and weight-loss measurements and potentiodynamic polarization were carried out to study the hot corrosion behavior of the weld in the simulated molten salt medium at 873 K, 973 K, and 1073 K (600 °C, 700 °C, and 800 °C). Internal oxidation and sulfidation plus pitting corrosion were identified as the main hot corrosion mechanisms in the weld and boiler tubes. The presence of a significant amount of Fe made the dendritic structure of the weld susceptible to preferential corrosion. Preferentially corroded (Mo, Nb)-depleted dendrite cores acted as potential sites for crack initiation from the surface layer. The penetration of the molten phase into the cracks accelerated the cracks' propagation mainly through the dendrite cores and further crack branching/widening.
Chandra Catches Early Phase of Cosmic Assembly
NASA Astrophysics Data System (ADS)
2004-08-01
A NASA Chandra X-ray Observatory image has revealed a complex of several intergalactic hot gas clouds in the process of merging. The superb Chandra spatial resolution made it possible to distinguish individual galaxies from the massive clouds of hot gas. One of the clouds, which that envelops hundreds of galaxies, has an extraordinarily low concentration of iron atoms, indicating that it is in the very early stages of cluster evolution. "We may be seeing hot intergalactic gas in a relatively pristine state before it has been polluted by gas from galaxies," said Q. Daniel Wang of the University of Massachusetts in Amherst, and lead author on an upcoming Astrophysical Journal article describing the study. "This discovery should provide valuable insight into how the most massive structures in the universe are assembled." 3-Panel Image of Abell 2125, Its Core & Galaxy C153 3-Panel Image of Abell 2125, Its Core & Galaxy C153 The complex, known as Abell 2125,is about 3 billion light years from Earth, and is seen at a time about 11 billion years after the Big Bang, when many galaxy clusters are believed to have formed. The Chandra Abell 2125 image shows several huge elongated clouds of multimillion degree gas coming together from different directions. These hot gas clouds, each of which contains hundreds of galaxies, appear to be in the process of merging to form a single massive galaxy cluster. Chandra, Hubble Space Telescope, and Very Large Array radio telescope data show that several galaxies in the Abell 2125 core cluster are being stripped of their gas as they fall through surrounding high-pressure hot gas. This stripping process has enriched the core cluster's gas in heavy elements such as iron. Abell 2125's Core & Galaxy C153 Abell 2125's Core & Galaxy C153 The gas in the pristine cloud, which is still several million light years away from the core cluster, is conspicuous for its lack of iron atoms. This anemic cloud must be in a very early evolutionary stage. The iron atoms produced by supernovas in the embedded galaxies must still be contained in and around the galaxies, perhaps in grains of dust not well mixed with the observed X-ray-emitting gas. Over time, as the cluster merges with the other clusters and the hot gas pressure increases, the dust grains will be driven from the galaxies, mixed with the hot gas, and destroyed, liberating the iron atoms. Building a massive galaxy cluster is a step-by-step enterprise that takes billions of years. Exactly how long it takes for such a cluster to form depends on many factors, such as the density of subclusters in the vicinity, the rate of the expansion of the universe, and the relative amounts of dark energy and dark matter. Chandra X-ray Image of Abell 2125, Low Energy Chandra X-ray Image of Abell 2125, Low Energy Cluster formation also involves complex interactions between the galaxies and the hot gas that may determine how large the galaxies in the cluster can ultimately become. These interactions determine how the galaxies maintain their gas content, the fuel for star formation. The observations of Abell 2125 provide a rare glimpse into the early steps in this process. NASA's Marshall Space Flight Center, Huntsville, Ala., manages the Chandra program for NASA's Office of Space Science, Washington. Northrop Grumman of Redondo Beach, Calif., formerly TRW, Inc., was the prime development contractor for the observatory. The Smithsonian Astrophysical Observatory controls science and flight operations from the Chandra X-ray Center in Cambridge, Mass. Additional information and images are available at: http://chandra.harvard.edu and http://chandra.nasa.gov
Combined facial heating and inhalation of hot air do not alter thermoeffector responses in humans.
Wingo, Jonathan E; Low, David A; Keller, David M; Kimura, Kenichi; Crandall, Craig G
2015-09-01
The influence of thermoreceptors in human facial skin on thermoeffector responses is equivocal; furthermore, the presence of thermoreceptors in the respiratory tract and their involvement in thermal homeostasis has not been elucidated. This study tested the hypothesis that hot air directed on the face and inhaled during whole body passive heat stress elicits an earlier onset and greater sensitivity of cutaneous vasodilation and sweating than that directed on an equal skin surface area away from the face. Six men and two women completed two trials separated by ∼1 wk. Participants were passively heated (water-perfused suit; core temperature increase ∼0.9°C) while hot air was directed on either the face or on the lower leg (counterbalanced). Skin blood flux (laser-Doppler flowmetry) and local sweat rate (capacitance hygrometry) were measured at the chest and one forearm. During hot-air heating, local temperatures of the cheek and leg were 38.4 ± 0.8°C and 38.8 ± 0.6°C, respectively (P = 0.18). Breathing hot air combined with facial heating did not affect mean body temperature onsets (P = 0.97 and 0.27 for arm and chest sites, respectively) or slopes of cutaneous vasodilation (P = 0.49 and 0.43 for arm and chest sites, respectively), or the onsets (P = 0.89 and 0.94 for arm and chest sites, respectively), or slopes of sweating (P = 0.48 and 0.65 for arm and chest sites, respectively). Based on these findings, respiratory tract thermoreceptors, if present in humans, and selective facial skin heating do not modulate thermoeffector responses during passive heat stress. Copyright © 2015 the American Physiological Society.
The "granite pump": LP/HT metamorphism and exhumation in the Montagne Nore (S-France)
NASA Astrophysics Data System (ADS)
Franke, W.; Doublier, M. P.; Doerr, W.; Stein, E.
2003-04-01
The Montagne Noire at the southern margin of the French Massif Central represents an exceptional case of a hot metamorphic core complex evolved from a thrust stack in a foreland position. The core of the structure (Zone Axiale) exposes granites and LP/HT gneisses up to anatectic grade. The hot core is encased by ENE-trending shear zones, which define a dextral pull-apart structure. Ductile extension is documented by top WSW shearing in the W, and ENE shearing in the E part of the Zone Axiale (eg, MATTE et al., 1998). Extension in ENE and reduction of the metamorphic profile are accompanied by NNW-directed contraction ("pinched pull-apart"). Palaeozoic sediments on the southern flank of the Zone Axiale exhibit only greenschist to diagenetic grades of metamorphism. Conodont alteration index (WIEDERER et al., 2002) and illite crystallinity (Doublier, this meeting) reveal a decrease of metamorphic temperature away from the hot core. Metamorphic isograds cut across the axial planes of D1 nappes. These features suggest that metamorphism was imposed by the rising hot core. Accordingly, the palaeozoic sediments show a tectonic evolution which closely resembles that of the gneissic core (extension top ENE, contraction in NNW). Structures relating to stacking (D1) have survived at the southern margin of the Montagne Noire. U-Pb studies (TIMS on single zircon and monazite) reveal peak metamorphism and magmatism already at c. 315 Ma (KLAMA et al., 2001), i.e., only <10 Ma after the end of flysch deposition in latest Visean/Early Namurian time (<= 323 Ma). The coincidence, within error, of the U-Pb ages and earlier Ar/Ar ages (MALUSKI et al., 1991) suggest rapid cooling. Synchronous granite emplacement and metamorphism is best explained by advective heating. Since granites are not generated in foreland settings, we propose derivation of the melts from areas of thickened crust adjacent to the N. Transport and emplacement of granites was essentially driven by the hydraulic gradient between the locus of melt generation in the orogenic root, and the opening pull-apart window. Such a pumping model may also be applied to other thermal anomalies in the Variscan Belt, e.g., in the SW-Bohemian Transverse Zone (FRANKE 2000), or in the Saxonian Granulites (FRANKE and STEIN 2000). Hydraulic expulsion of hot, low viscously materials has played an important role in the transport of heat for the hot Variscan root to higher and more external parts of the crust. FRANKE (2000); Geol. Soc. Spec. Publ. No. 179, 35-63. FRANKE and STEIN (2000); Geol. Soc. Spec. Publ. No. 179, 337-355. KLAMA et al. (2001); J. Conf. Abs.,6, 235. MALUSKI et al. (1991); Lithos, 26: 287-304. MATTE et al. (1998); Geodynamica Acta: 13-22. WIEDERER et al. (2002); Schweiz. Mineral. Petrogr. Mitt. 82, 393-407.
CYGNUS A: Hot Spots, Bow Shocks, Core Emission, and Exclusion of Cluster Gas by Radio Lobes
NASA Technical Reports Server (NTRS)
Harris, Daniel E.
1999-01-01
This report covers work preformed on three ROSAT projects: (1) Monitoring the X-ray Intensity of the Core and Jet of M87; (2) The radio-optical jet in 3C-120 and (3) A search for cluster emission at high redshift.
Barium titanate core--gold shell nanoparticles for hyperthermia treatments.
FarrokhTakin, Elmira; Ciofani, Gianni; Puleo, Gian Luigi; de Vito, Giuseppe; Filippeschi, Carlo; Mazzolai, Barbara; Piazza, Vincenzo; Mattoli, Virgilio
2013-01-01
The development of new tools and devices to aid in treating cancer is a hot topic in biomedical research. The practice of using heat (hyperthermia) to treat cancerous lesions has a long history dating back to ancient Greece. With deeper knowledge of the factors that cause cancer and the transmissive window of cells and tissues in the near-infrared region of the electromagnetic spectrum, hyperthermia applications have been able to incorporate the use of lasers. Photothermal therapy has been introduced as a selective and noninvasive treatment for cancer, in which exogenous photothermal agents are exploited to achieve the selective destruction of cancer cells. In this manuscript, we propose applications of barium titanate core-gold shell nanoparticles for hyperthermia treatment against cancer cells. We explored the effect of increasing concentrations of these nanoshells (0-100 μg/mL) on human neuroblastoma SH-SY5Y cells, testing the internalization and intrinsic toxicity and validating the hyperthermic functionality of the particles through near infrared (NIR) laser-induced thermoablation experiments. No significant changes were observed in cell viability up to nanoparticle concentrations of 50 μg/mL. Experiments upon stimulation with an NIR laser revealed the ability of the nanoshells to destroy human neuroblastoma cells. On the basis of these findings, barium titanate core-gold shell nanoparticles resulted in being suitable for hyperthermia treatment, and our results represent a promising first step for subsequent investigations on their applicability in clinical practice.
A New Formation Mechanism for the Hottest Horizontal-Branch Stars
NASA Technical Reports Server (NTRS)
Sweigart, Allen V.; Oegerle, William R. (Technical Monitor)
2002-01-01
Hot subluminous stars lying up to 0.7 mag below the extreme horizontal branch (EHB) are found in the ultraviolet color-magnitude diagrams (CMDs) of both omega Cen and NGC 2808. In order to investigate the origin of these subluminous stars, we have constructed a detailed set of evolutionary sequences that follow the evolution of low-mass stars continuously from the zero-age main sequence through the helium-core flash to the HB for a wide range in the mass loss along the red-giant branch (RGB). Stars with the largest mass loss evolve off the RGB to high effective temperatures before igniting helium in their cores. Our results indicate that the subluminous EHB stars, as well as the high temperature gap along the EHB of NGC 2808, can be explained if these stars undergo a late helium-core flash while descending the white-dwarf cooling curve. Under these conditions the convection zone produced by the main helium flash will penetrate into the stellar envelope, thereby mixing most, if not all, of the envelope hydrogen into the hot helium-burning interior, where it is rapidly consumed. This phenomenon is analogous to the 'born-again' scenario for producing hydrogen-deficient stars following a very late helium-shell flash. This 'flash mixing' of the envelope during a late helium-core flash greatly enhances the envelope helium and carbon abundances and, as a result, leads to a discontinuous increase in the HB effective temperature. We argue that the hot HB gap observed in NGC 2808 is associated with this theoretically predicted dichotomy in the RB properties. Using new helium- and carbon-rich stellar atmospheres, we show that the changes in the envelope abundances due to flash mixing will suppress the ultraviolet flux in the spectra of hot EHB stars. We suggest that such changes in the emergent spectral energy distribution are primarily responsible for explaining the hot subluminous EHB stars in omega Cen and NGC 2808. Moreover, we demonstrate that models without flash mixing lie, at most, only approximately 0.1 mag below the EHB, and hence fail to explain the observations.
Ultraviolet properties of individual hot stars in globular cluster cores. 1: NGC 1904 (M 79)
NASA Technical Reports Server (NTRS)
Altner, Bruce; Matilsky, Terry A.
1992-01-01
As part of an observing program using the International Ultraviolet Explorer (IUE) satellite to investigate the ultraviolet properties of stars found within the cores of galactic globular clusters with blue horizontal branches (HBs), we obtained three spectra of the cluster NGC 1904 (M 79). All three were long integration-time, short-wavelength (SWP) spectra obtained at the so called 'center of light' and all three showed evidence of sources within the IUE large aperture (21.4 in. by 10 in.). In this paper we shall describe the analysis of these spectra and present evidence that the UV sources represent individual hot stars in the post-HB stage of evolution.
NASA Astrophysics Data System (ADS)
Kawanami, Shoko; Horie, Seichi; Inoue, Jinro; Yamashita, Makiko
2012-11-01
Workers working in hot or cold environments are at risk for heat stroke and hypothermia. In Japan, 1718 people including 47 workers died of heat stroke in 2010 (Ministry of Health Labour and Welfare, Japan 2011). While the American Conference of Governmental Industrial Hygienists (ACGIH) recommendation lists the abnormal core temperature of workers as a criterion for halting work, no method has been established for reliably measuring core temperatures at workplaces. ISO 9886 (Ergonomics-evaluation of thermal strain by physiological measurements. ISO copyright office, Geneva, pp 3-14; 2004) recognizes urine temperature as an index of core temperature only at normal temperature. In this study we ascertained whether or not urine temperature could serve as an index for core temperature at temperatures above and below the ISO range. We measured urine temperature of 31 subjects (29.8 ± 11.9 years) using a thermocouple sensor placed in the toilet bowl at ambient temperature settings of 40, 20, and 5˚C, and compared them with rectal temperature. At all ambient temperature settings, urine temperature correlated closely with rectal temperature exhibiting small mean bias. Urine temperature changed in a synchronized manner with rectal temperature at 40˚C. A Bland and Altman analysis showed that the limits of agreement (mean bias ± 2SD) between rectal and urine temperatures were -0.39 to +0.15˚C at 40˚C (95%CI -0.44 to +0.20˚C) and -0.79 to +0.29˚C at 5˚C (-0.89 to +0.39˚C). Hence, urine temperature as measured by the present method is a practical surrogate index for rectal temperature and represents a highly reliable biological monitoring index for assessing hot and cold stresses of workers at actual workplaces.
NASA Astrophysics Data System (ADS)
Goddi, C.; Ginsburg, A.; Zhang, Q.
2016-05-01
Context. This paper is the third in a series of NH3 multilevel imaging studies in well-known, high-mass star-forming regions. The main goal is to characterize kinematics and physical conditions of (hot and dense) circumstellar molecular gas around O-type young stars. Aims: We want to map at subarcsecond resolution highly excited inversion lines of NH3 in the high-mass star-forming region W51 Main (distance = 5.4 kpc), which is an ideal target to constrain theoretical models of high-mass star formation. Methods: Using the Karl Jansky Very Large Array (JVLA), we mapped the hot and dense molecular gas in W51 Main with ~0.2 arcsec-0.3 arcsec angular resolution in five metastable (J = K) inversion transitions of ammonia (NH3): (J,K) = (6, 6), (7, 7), (9, 9), (10, 10), and (13, 13). These lines arise from energy levels between ~400 K and ~1700 K above the ground state. We also made maps of the (free-free) continuum emission at frequencies between 25 and 36 GHz. Results: We have identified and characterized two main centers of high-mass star formation in W51 Main, which excite hot cores and host one or multiple high-mass young stellar objects (YSOs) at their centers: the W51e2 complex and the W51e8 core (~6'' southward of W51e2). The former breaks down into three further subcores: W51e2-W, which surrounds the well-known hypercompact (HC) HII region, where hot NH3 is observed in absorption, and two additional dusty cores, W51e2-E (~0.8 arcsec to the East) and W51e2-NW (~1'' to the North), where hot NH3 is observed in emission. The velocity maps toward the HC HII region show a clear velocity gradient along the east-west in all lines. The gradient may indicate rotation, although any Keplerian motion must be on smaller scales (<1000 AU) as we do not directly observe a Keplerian velocity profile. The absence of outflow and/or maser activity and the low amount of molecular gas available for accretion (~5 M⊙, assuming [NH3]/[H2] = 10-7) with respect to the mass of the central YSO estimated from radio luminosity (>20 M⊙), both indicate that the central YSO has already accreted most of its final mass. On the other hand, the nearby W51e2-E, while not showing evidence of rotation, shows signatures of infall in a hot dense core (T ~ 170 K, nH2 ~ 5 × 107 cm-3), based on asymmetric spectral profiles (skewed toward the blueshifted component) in optically thick emission lines of NH3. The relatively large amount of hot molecular gas available for accretion (~20 M⊙ within about half an arcsecond or 2500 AU), along with strong outflow and maser activity, indicates that the main accretion center in the W51e2 complex is W51e2-E rather than W51e2-W. Finally, W51e2-NW and W51e8, although less dense (nH2 ~ 2 × 107 cm-3 and ~ 3 × 106 cm-3), are also hot cores (Tgas ~ 140 and 200 K) and contain a significant amount of molecular gas (Mgas ~ 30M⊙ and ~70 M⊙, respectively). We speculate that they may host high-mass YSOs either at a previous evolutionary stage or with a mass that is lower than W51e2-E and W51e2-W. Conclusions: Using high-angular resolution multilevel imaging of highly excited NH3 metastable lines, we characterized the physical and dynamical properties of four individual high-mass young stars forming in the W51 Main clump. The reduced NH3 data cubes as FITS files are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/589/A44
Bailey, Tom G; Cable, N Timothy; Aziz, Nabil; Dobson, Rebecca; Sprung, Victoria S; Low, David A; Jones, Helen
2016-07-01
Postmenopausal hot flushes occur due to a reduction in estrogen production causing thermoregulatory and vascular dysfunction. Exercise training enhances thermoregulatory control of sweating, skin and brain blood flow. We aimed to determine if improving thermoregulatory control and vascular function with exercise training alleviated hot flushes. Twenty-one symptomatic women completed a 7-day hot flush questionnaire and underwent brachial artery flow-mediated dilation and a cardiorespiratory fitness test. Sweat rate and skin blood flow temperature thresholds and sensitivities, and middle cerebral artery velocity (MCAv) were measured during passive heating. Women performed 16 weeks of supervised exercise training or control, and measurements were repeated. There was a greater improvement in cardiorespiratory fitness (4.45 mL/kg/min [95% CI: 1.87, 8.16]; P = 0.04) and reduced hot flush frequency (48 hot flushes/wk [39, 56]; P < 0.001) after exercise compared with control. Exercise reduced basal core temperature (0.14°C [0.01, 0.27]; P = 0.03) and increased basal MCAv (2.8 cm/s [1.0, 5.2]; P = 0.04) compared with control. Sweat rate and skin blood flow thresholds occurred approximately 0.19°C and 0.17°C earlier, alongside improved sweating sensitivity with exercise. MCAv decreased during heating (P < 0.005), but was maintained 4.5 cm/s (3.6, 5.5; P < 0.005) higher during heating after exercise compared with control (0.6 cm/s [-0.4, 1.4]). Exercise training that improves cardiorespiratory fitness reduces self-reported hot flushes. Improvements are likely mediated through greater thermoregulatory control in response to increases in core temperature and enhanced vascular function in the cutaneous and cerebral circulations.
NASA Technical Reports Server (NTRS)
Brown, Thomas M.; Sweigart, Allen V.; Lanz, Thierry; Landsman, Wayne B.; Hubeny, Ivan; Fisher, Richard R. (Technical Monitor)
2001-01-01
We present an ultraviolet color-magnitude diagram (CMD) spanning the hot horizontal branch (HB), blue straggler, and white dwarf populations of the globular cluster NGC 2808. These data, obtained with the Space Telescope Imaging Spectrograph (STIS), demonstrate that NGC 2808 harbors a significant population of hot subluminous HB stars, an anomaly only previously reported for the globular cluster omega Cen. Our theoretical modeling indicates that the location of these subluminous stars in the CMD, as well as the high temperature gap along the HB of NGC 2808, can be explained if these stars underwent a late helium-core flash while descending the white dwarf cooling curve. We show that the convective zone produced by such a late helium flash will penetrate into the hydrogen envelope, thereby mixing hydrogen into the hot helium-burning interior, where it is rapidly consumed. This phenomenon is analogous to the "born again" scenario for producing hydrogen-deficient stars following a late helium-shell flash. The flash mixing of the envelope greatly enhances the envelope helium and carbon abundances that, in turn, leads to a discontinuous increase in the HB effective temperatures. We argue that the hot HB gap is associated with this theoretically predicted dichotomy in the HB properties. Moreover, the changes in the emergent spectral energy distribution caused by these abundance changes are primarily responsible for explaining the hot subluminous HB stars. Although further evidence is needed to confirm that a late helium-core flash can account for the subluminous HB stars and the hot HB gap, we demonstrate that an understanding of these stars requires the use of appropriate theoretical models for their evolution, atmospheres, and spectra.
Thinking in New Ways and in New Times about Reading
ERIC Educational Resources Information Center
Leu, Donald J.; Maykel, Cheryl
2016-01-01
Over the years, the annual "What's Hot, What's Not" survey by Jack Cassidy has served as an important indicator for issues in the continuously changing landscape of literacy education within North America. In "Beyond the Common Core," Cassidy, Ortlieb, and GroteGarcia (2016) note the meteoric rise of the Common Core State…
NASA Astrophysics Data System (ADS)
Geier, S.
2015-06-01
Hot subdwarfs are considered to be the compact helium cores of red giants which lost almost their entire hydrogen envelope. What causes this enormous mass loss is still unclear. Binary interactions are invoked, and a significant fraction of the hot subdwarf population is indeed found in close binaries. In a large project we search for close binary sdBs with the most and the least massive companions. Significantly enhancing the known sample of close binary sdBs we performed the first comprehensive study of this population. Triggered by the discovery of two sdB binaries with close brown dwarf companions in the course of this project, we were able to show that the interaction of stars with substellar companions is an important channel to form sdB stars. Finally, we discovered a unique and very compact binary system consisting of an sdB and a massive white dwarf which qualifies as a progenitor candidate for a supernova of type Ia. In addition to that, we could connect those explosions to the class of hypervelocity hot subdwarf stars which we consider as the surviving companions of such events. Being the stripped cores of red giants, hot subdwarfs turned out to be important markers of peculiar events in stellar evolution ranging all the way from star-planet interactions to the progenitors of stellar explosions used to measure the expansion of our Universe.
NASA Astrophysics Data System (ADS)
Jetté, Maurice; Quenneville, Josée; Thoden, James; Livingstone, Sydney
1992-09-01
The effects of inspiratory resistance on prolonged work in a hot environment wearing a nuclear, bacteriological and chemical warfare (NBCW) mask and overgarment were assessed in 10 males. Subjects walked on a treadmill at 5 km/hr, 2% gradient, until their core temperature reached 39° C or for a duration of 90 min. Rectal temperature, heart rate, ventilation, oxygen consumption and rate of perceived breathing were measured. There were no differences between break-point time without the canister (62.2 ± 21 min) and with the canister (58.9 ± 17 min). Regression analysis indicated that the mean core temperature increased by 0.02° C for every minute of work performed and heart rate by 6 beats/min for every increase of 0.2° C in core temperature. Reduction in heat transfer brought about by wearing the protective overgarment and mask with or without the canister will significantly increase core temperature and limit the performance of moderate work to approximately 1 h in a moderately fit individual.
Sombrero-shaped plasmonic nanoparticles with molecular-level sensitivity and multifunctionality.
Wi, Jung-Sub; Barnard, Edward S; Wilson, Robert J; Zhang, Mingliang; Tang, Mary; Brongersma, Mark L; Wang, Shan X
2011-08-23
We demonstrate top-down synthesis of monodisperse plasmonic nanoparticles designed to contain internal Raman hot spots. Our Raman-active nanoparticles are fabricated using nanoimprint lithography and thin-film deposition and are composed of novel internal structures with sublithographic dimensions: a disk-shaped Ag core, a Petri-dish-shaped SiO(2) base whose inner surface is coated with Ag film, and a sub-10 nm scale circular gap between the core and the base. Confocal Raman measurements and electromagnetic simulations show that Raman hot spots appear at the inside perimeter of individual nanoparticles and serve as the source of a 1000-fold improvement of minimum molecular detection level that enables detection of signals from a few molecules near hot spots. A multimodality version of these nanoparticles, which includes the functionality offered by magnetic multilayers, is also demonstrated. These results illustrate the potential of direct fabrication for creating exotic monodisperse nanoparticles, which combine engineered internal nanostructures and multilayer composite materials, for use in nanoparticle-based molecular imaging and detection. © 2011 American Chemical Society
Tippet, Melissa L.; Stofan, John R.; Lacambra, Magie; Horswill, Craig A.
2011-01-01
Abstract Context: Tennis is often played in hot, humid environments, intensifying the thermoregulatory strain placed on the athletes. As a safety measure, some tennis organizations allow for a 10-minute break in play between the second and third sets when environmental conditions are extreme. However, the actual effect of these breaks in reducing core temperature is unknown. Objective: To determine change in core temperature after a 10-minute break in play and assess fluid balance in professional female tennis players during tournament matches in the heat. Design: Cross-sectional study. Setting: A Women's Tennis Association Tour–sanctioned outdoor tournament on hard courts under hot conditions (30.3°C ± 2.3°C). Patients or Other Participants: Seven professional tennis players. Main Outcome Measure(s): Change in core temperature after a 10-minute break in tournament play, fluid intake, and sweat losses during match play. Results: Core temperature was reduced from 38.92°C to 38.67°C (change of −0.25°C ± 0.20°C) when a break was taken (P = .02). Mean sweat rate during match play was 2.0 ± 0.5 L/h. During that time, mean fluid intake was 1.5 ± 0.5 L/h, resulting in a 1.2% ± 1.0% reduction in body mass. Conclusions: Female professional tennis players are subjected to high heat loads during match play in hot environments. However, a 10-minute break in play decreased core temperature in 6 of 7 players by an average of 0.25°C, indicating that the break provides practical benefits in the field. Furthermore, although mean sweat rate in this group of female tennis players was high, most athletes were still able to minimize mass loss to less than 2% of their prematch weight. PMID:21214351
Chemical segregation in hot cores with disk candidates. An investigation with ALMA
NASA Astrophysics Data System (ADS)
Allen, V.; van der Tak, F. F. S.; Sánchez-Monge, Á.; Cesaroni, R.; Beltrán, M. T.
2017-07-01
Context. In the study of high-mass star formation, hot cores are empirically defined stages where chemically rich emission is detected toward a massive YSO. It is unknown whether the physical origin of this emission is a disk, inner envelope, or outflow cavity wall and whether the hot core stage is common to all massive stars. Aims: We investigate the chemical makeup of several hot molecular cores to determine physical and chemical structure. We use high spectral and spatial resolution submillimeter observations to determine how this stage fits into the formation sequence of a high-mass star. Methods: The submillimeter interferometer ALMA (Atacama Large Millimeter Array) was used to observe the G35.20-0.74N and G35.03+0.35 hot cores at 350 GHz in Cycle 0. We analyzed spectra and maps from four continuum peaks (A, B1, B2 and B3) in G35.20-0.74N, separated by 1000-2000 AU, and one continuum peak in G35.03+0.35. We made all possible line identifications across 8 GHz of spectral windows of molecular emission lines down to a 3σ line flux of 0.5 K and determined column densities and temperatures for as many as 35 species assuming local thermodynamic equilibrium (LTE). Results: In comparing the spectra of the four continuum peaks, we find each has a distinct chemical composition expressed in over 400 different transitions. In G35.20, B1 and B2 contain oxygen- and sulfur-bearing organic and inorganic species but few nitrogen-bearing species whereas A and B3 are strong sources of O-, S-, and N-bearing organic and inorganic species (especially those with the CN bond). Column densities of vibrationally excited states are observed to be equal to or greater than the ground state for a number of species. Deuterated methyl cyanide is clearly detected in A and B3 with D/H ratios of 8 and 13%, respectively, but is much weaker at B1 and undetected at B2. No deuterated species are detected in G35.03, but similar molecular abundances to G35.20 were found in other species. We also find co-spatial emission of isocyanic acid (HNCO) and formamide (NH2CHO) in both sources indicating a strong chemical link between the two species. Conclusions: The chemical segregation between N-bearing organic species and others in G35.20 suggests the presence of multiple protostars surrounded by a disk or torus.
Passive shut-down heat removal system
Hundal, Rolv; Sharbaugh, John E.
1988-01-01
An improved shut-down heat removal system for a liquid metal nuclear reactor of the type having a vessel for holding hot and cold pools of liquid sodium is disclosed herein. Generally, the improved system comprises a redan or barrier within the reactor vessel which allows an auxiliary heat exchanger to become immersed in liquid sodium from the hot pool whenever the reactor pump fails to generate a metal-circulating pressure differential between the hot and cold pools of sodium. This redan also defines an alternative circulation path between the hot and cold pools of sodium in order to equilibrate the distribution of the decay heat from the reactor core. The invention may take the form of a redan or barrier that circumscribes the inner wall of the reactor vessel, thereby defining an annular space therebetween. In this embodiment, the bottom of the annular space communicates with the cold pool of sodium, and the auxiliary heat exchanger is placed in this annular space just above the drawn-down level that the liquid sodium assumes during normal operating conditions. Alternatively, the redan of the invention may include a pair of vertically oriented, concentrically disposed standpipes having a piston member disposed between them that operates somewhat like a pressure-sensitive valve. In both embodiments, the cessation of the pressure differential that is normally created by the reactor pump causes the auxiliary heat exchanger to be immersed in liquid sodium from the hot pool. Additionally, the redan in both embodiments forms a circulation flow path between the hot and cold pools so that the decay heat from the nuclear core is uniformly distributed within the vessel.
NASA Astrophysics Data System (ADS)
Klein, Randolf; Looney, Leslie; Henning, Thomas; Chakrabarti, Sukanya; Shenoy, Sachin
2015-08-01
Infrared Dark Clouds (IRDCs) are very good candidates for the earliest phases of massive star formation, but can only be found in regions with high infrared background. We have searched for early phases among cold and massive (M>100M⊙) cloud cores by selecting cores from millimeter continuum surveys (Faundez et al. 2004, Sridharan et al. 2005, Klein et al. 2005, Beltran et al. 2006) without associations at short wavelengths. We compared the millimeter continuum peak positions with IR and radio catalogs (2MASS, MSX, IRAS, and NVSS) and excluded cores that had sources associated with the cores' peaks. We compiled a list of 173 cores in over 117 regions that are candidates for very early phases of Massive Star Formation (MSF). Now with the Spitzer and Herschel archives, these cores can be characterized further. The GLIMPSE and MIPSGAL programs alone covered 86 of these regions. The Herschel Archive adds even longer wavelengths. We are compiling this data set to construct the complete spectral energy distribution (SED) in the mid- and far-infrared with good spatial resolution and broad spectral coverage. This allow us to disentangle the complex regions and model the SED of the deeply embedded protostars/clusters.We will be presenting the IR properties of all cores and their embedded source, attempt a characterization, and order the cores in an evolutionary sequence. The resulting properties can be compared to e.g. IRDCs, a class of objects suggested to be the earliest stages of MSF. With the relative large number of cores, we can try to answer questions like: How homogeneous or diverse are our regions in terms of their evolutionary stage? Where do our embedded sources fit in the evolutionary sequence of IRDCs, hot molecular cores, ultra-compact HII regions, etc? How is the MSF shaping the environment and vice versa? Can we extrapolate to the initial conditions of MSF using our evolutionary sequence?
Ravanelli, Nicholas; Casasola, William; English, Timothy; Edwards, Kate M; Jay, Ollie
2018-03-01
Pregnant women are advised to avoid heat stress (eg, excessive exercise and/or heat exposure) due to the risk of teratogenicity associated with maternal hyperthermia; defined as a core temperature (T core ) ≥39.0°C. However, guidelines are ambiguous in terms of critical combinations of climate and activity to avoid and may therefore unnecessarily discourage physical activity during pregnancy. Thus, the primary aim was to assess T core elevations with different characteristics defining exercise and passive heat stress (intensity, mode, ambient conditions, duration) during pregnancy relative to the critical maternal T core of ≥39.0°C. Systematic review with best evidence synthesis. EMBASE, MEDLINE, SCOPUS, CINAHL and Web of Science were searched from inception to 12 July 2017. Studies reporting the T core response of pregnant women, at any period of gestation, to exercise or passive heat stress, were included. 12 studies satisfied our inclusion criteria (n=347). No woman exceeded a T core of 39.0°C. The highest T core was 38.9°C, reported during land-based exercise. The highest mean end-trial T core was 38.3°C (95% CI 37.7°C to 38.9°C) for land-based exercise, 37.5°C (95% CI 37.3°C to 37.7°C) for water immersion exercise, 36.9°C (95% CI 36.8°C to 37.0°C) for hot water bathing and 37.6°C (95% CI 37.5°C to 37.7°C) for sauna exposure. The highest individual core temperature reported was 38.9°C. Immediately after exercise (either land based or water immersion), the highest mean core temperature was 38.3°C; 0.7°C below the proposed teratogenic threshold. Pregnant women can safely engage in: (1) exercise for up to 35 min at 80%-90% of their maximum heart rate in 25°C and 45% relative humidity (RH); (2) water immersion (≤33.4°C) exercise for up to 45 min; and (3) sitting in hot baths (40°C) or hot/dry saunas (70°C; 15% RH) for up to 20 min, irrespective of pregnancy stage, without reaching a core temperature exceeding the teratogenic threshold. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Multiple Days of Heat Exposure on Firefighters' Work Performance and Physiology.
Larsen, Brianna; Snow, Rod; Vincent, Grace; Tran, Jacqueline; Wolkow, Alexander; Aisbett, Brad
2015-01-01
This study assessed the accumulated effect of ambient heat on the performance of, and physiological and perceptual responses to, intermittent, simulated wildfire fighting tasks over three consecutive days. Firefighters (n = 36) were matched and allocated to either the CON (19°C) or HOT (33°C) condition. They performed three days of intermittent, self-paced simulated firefighting work, interspersed with physiological testing. Task repetitions were counted (and converted to distance or area) to determine work performance. Participants were asked to rate their perceived exertion and thermal sensation after each task. Heart rate, core temperature (Tc), and skin temperature (Tsk) were recorded continuously throughout the simulation. Fluids were consumed ad libitum. Urine volume was measured throughout, and urine specific gravity (USG) analysed, to estimate hydration. All food and fluid consumption was recorded. There was no difference in work output between experimental conditions. However, significant variation in performance responses between individuals was observed. All measures of thermal stress were elevated in the HOT, with core and skin temperature reaching, on average, 0.24 ± 0.08°C and 2.81 ± 0.20°C higher than the CON group. Participants' doubled their fluid intake in the HOT condition, and this was reflected in the USG scores, where the HOT participants reported significantly lower values. Heart rate was comparable between conditions at nearly all time points, however the peak heart rate reached each circuit was 7 ± 3% higher in the CON trial. Likewise, RPE was slightly elevated in the CON trial for the majority of tasks. Participants' work output was comparable between the CON and HOT conditions, however the performance change over time varied significantly between individuals. It is likely that the increased fluid replacement in the heat, in concert with frequent rest breaks and task rotation, assisted with the regulation of physiological responses (e.g., heart rate, core temperature).
Control of reactor coolant flow path during reactor decay heat removal
Hunsbedt, Anstein N.
1988-01-01
An improved reactor vessel auxiliary cooling system for a sodium cooled nuclear reactor is disclosed. The sodium cooled nuclear reactor is of the type having a reactor vessel liner separating the reactor hot pool on the upstream side of an intermediate heat exchanger and the reactor cold pool on the downstream side of the intermediate heat exchanger. The improvement includes a flow path across the reactor vessel liner flow gap which dissipates core heat across the reactor vessel and containment vessel responsive to a casualty including the loss of normal heat removal paths and associated shutdown of the main coolant liquid sodium pumps. In normal operation, the reactor vessel cold pool is inlet to the suction side of coolant liquid sodium pumps, these pumps being of the electromagnetic variety. The pumps discharge through the core into the reactor hot pool and then through an intermediate heat exchanger where the heat generated in the reactor core is discharged. Upon outlet from the heat exchanger, the sodium is returned to the reactor cold pool. The improvement includes placing a jet pump across the reactor vessel liner flow gap, pumping a small flow of liquid sodium from the lower pressure cold pool into the hot pool. The jet pump has a small high pressure driving stream diverted from the high pressure side of the reactor pumps. During normal operation, the jet pumps supplement the normal reactor pressure differential from the lower pressure cold pool to the hot pool. Upon the occurrence of a casualty involving loss of coolant pump pressure, and immediate cooling circuit is established by the back flow of sodium through the jet pumps from the reactor vessel hot pool to the reactor vessel cold pool. The cooling circuit includes flow into the reactor vessel liner flow gap immediate the reactor vessel wall and containment vessel where optimum and immediate discharge of residual reactor heat occurs.
Multiple Days of Heat Exposure on Firefighters’ Work Performance and Physiology
Larsen, Brianna; Snow, Rod; Vincent, Grace; Tran, Jacqueline; Wolkow, Alexander; Aisbett, Brad
2015-01-01
This study assessed the accumulated effect of ambient heat on the performance of, and physiological and perceptual responses to, intermittent, simulated wildfire fighting tasks over three consecutive days. Firefighters (n = 36) were matched and allocated to either the CON (19°C) or HOT (33°C) condition. They performed three days of intermittent, self-paced simulated firefighting work, interspersed with physiological testing. Task repetitions were counted (and converted to distance or area) to determine work performance. Participants were asked to rate their perceived exertion and thermal sensation after each task. Heart rate, core temperature (Tc), and skin temperature (Tsk) were recorded continuously throughout the simulation. Fluids were consumed ad libitum. Urine volume was measured throughout, and urine specific gravity (USG) analysed, to estimate hydration. All food and fluid consumption was recorded. There was no difference in work output between experimental conditions. However, significant variation in performance responses between individuals was observed. All measures of thermal stress were elevated in the HOT, with core and skin temperature reaching, on average, 0.24 ± 0.08°C and 2.81 ± 0.20°C higher than the CON group. Participants’ doubled their fluid intake in the HOT condition, and this was reflected in the USG scores, where the HOT participants reported significantly lower values. Heart rate was comparable between conditions at nearly all time points, however the peak heart rate reached each circuit was 7 ± 3% higher in the CON trial. Likewise, RPE was slightly elevated in the CON trial for the majority of tasks. Participants’ work output was comparable between the CON and HOT conditions, however the performance change over time varied significantly between individuals. It is likely that the increased fluid replacement in the heat, in concert with frequent rest breaks and task rotation, assisted with the regulation of physiological responses (e.g., heart rate, core temperature). PMID:26379284
NASA Technical Reports Server (NTRS)
Milam, S. N.; Charnley, S. B.
2011-01-01
Isotopically fractionated material is found in many solar system objects, including meteorites and comets. It is thought, in some cases, to trace interstellar material that was incorporated into the solar system without undergoing significant processing. Here, we show the results of models and observations of the nitrogen and carbon fractionation in proto-stellar cores.
Near infrared observations of S155. evidence of induced star formation?
NASA Astrophysics Data System (ADS)
Hunt, L. K.; Lisi, F.; Felli, M.; Tofani, G.
At the interface of the giant molecular cloud Cepheus OB3, S155 represents one of the most interesting examples of bright rim produced by the ionization of a nearby O-star. The interaction between the ionized HII region S155 and the hot molecular core Cepheus B may constitute the ideal site for new stars, according to the sequential star-formation theory. Past observations of molecular lines have shown the evidence of a hot spot in the cloud core, probably a compact region associated to a young stellar object. New J,H,K images recently obtained with the ARNICA array at the TIRGO telescope give evidence of stars with strong near-infrared excess, which must represent the newest generation of young stars.
MC21 analysis of the MIT PWR benchmark: Hot zero power results
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kelly Iii, D. J.; Aviles, B. N.; Herman, B. R.
2013-07-01
MC21 Monte Carlo results have been compared with hot zero power measurements from an operating pressurized water reactor (PWR), as specified in a new full core PWR performance benchmark from the MIT Computational Reactor Physics Group. Included in the comparisons are axially integrated full core detector measurements, axial detector profiles, control rod bank worths, and temperature coefficients. Power depressions from grid spacers are seen clearly in the MC21 results. Application of Coarse Mesh Finite Difference (CMFD) acceleration within MC21 has been accomplished, resulting in a significant reduction of inactive batches necessary to converge the fission source. CMFD acceleration has alsomore » been shown to work seamlessly with the Uniform Fission Site (UFS) variance reduction method. (authors)« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rabin, S.A.; Martin, M.M.; Lotts, A.L.
The fabricability of dispersion fuels using UO/sub 2/ or UC as the dispersoid and uranium combined with 10 to 15 wt% Mo as the matrix was investigated. Cores containing l7.8 wt% UO/sub 2/ dispersed in U-- 15 wt.% Mo were successfully fabricated to about 80% of theoretical density by cold pressing at 50 tsi, sintering at 1100 deg C, and cold coining at 50 tsi. Comparable results were obtained with UC as the dispersoid. Core fabrication results varied greatly with the type of matrix powder used. Occluded gases, pour density, and surface cleanliness bore important relations to the fabrication behaviormore » of powders. Suitable pressing and sintering results were obtained with prealloyed, calcium-reduced U--Mo powder and with molybdenum and calcium-reduced uranium as elemental powders. Shotted prealloyed powders were difficult to press and sinter, as were elemental and prealloyed powders prepared by hydriding. The cores containing UO/sub 2/ were picture-frame, hot-roll-clad as miniature plates. Molybdenum, Fansteel 82, and Zr--3 wt% Al were investigated as cladding materials. While each bonded well to itself, only the molybdenum-clad core, rolled at 1150 deg C to 10/1 reduction, resulted in dispersions free of ruptures and UO/sub 2/ fragmentation and in strong bonding to the core, evaluated by metallography, mechanical peel, and thermal shock tests. The matrix phase was homogeneous, but the UO/sub 2/ dispersoid showed stringering characteristic of cores worked by hot rolling. Core densities as high as 99% of theoretical were obtained. (auth)« less
NASA Astrophysics Data System (ADS)
Nunez, Luis Ernesto; Johnson, John A.
2017-01-01
Hot Jupiters are Jupiter-sized gas giant exoplanets that closely orbit their host star in periods of about 10 days or less. Early models hypothesized that these exoplanets formed away from the star, then over time drifted to their characteristically closer locations. However, new theories predict that Hot Jupiters form at their close proximity during the process of core accretion (Batygin et al. 2015). In fact, a super-Earth and a Neptune-sized exoplanet have already been detected in the Hot Jupiter-hosting star WASP-47 (Becker et al. 2015). We will present our analysis of radial velocity time series plots to determine whether low-mass, short-period planets have been previously overlooked in systems of stars which host Hot Jupiters.The SAO REU program is funded in part by the National Science Foundation REU and Department of Defense ASSURE programs under NSF Grant no. 1262851.
Investigating La Réunion Hot Spot From Crust to Core
NASA Astrophysics Data System (ADS)
Barruol, Guilhem; Sigloch, Karin
2013-06-01
Whether volcanic intraplate hot spots are underlain by deep mantle plumes continues to be debated 40 years after the hypothesis was proposed by Morgan [1972]. Arrivals of buoyant plume heads may have been among the most disruptive agents in Earth's history, initiating continental breakup, altering global climate, and triggering mass extinctions. Further, with the temporary shutdown of European air traffic in 2010 caused by the eruption of Eyjafjallajökull, a geologically routine eruption in the tail end of the presumed Iceland plume, the world witnessed an intrusion of hot spot activity into modern-day life.
Stability of hot electron plasma in the ELMO bumpy torus
NASA Astrophysics Data System (ADS)
Tsang, K. T.; Cheng, C. Z.
The stability of a hot electron plasma in the ELMO Bumpy Torus was investigated using two different models. In the first model, where the hot electron distribution function is assumed to be a delta function in the perpendicular velocity, a stability boundary in addition to those discussed by Nelson and by Van Dam and Lee is found. In the second model, where the hot electron distribution function is assumed to be a Maxwellian in the perpendicular velocity, stability boundaries significantly different from those of the first model are found. Coupling of the Nelson-Van Dam-Lee mode to the compressional Alfven mode is now possible. This leads to a higher permissible core plasma beta value for stable operation.
Mass-loss evolution of close-in exoplanets: Evaporation of hot Jupiters and the effect on population
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kurokawa, H.; Nakamoto, T., E-mail: kurokawa@nagoya-u.jp
2014-03-01
During their evolution, short-period exoplanets may lose envelope mass through atmospheric escape owing to intense X-ray and extreme ultraviolet (XUV) radiation from their host stars. Roche-lobe overflow induced by orbital evolution or intense atmospheric escape can also contribute to mass loss. To study the effects of mass loss on inner planet populations, we calculate the evolution of hot Jupiters considering mass loss of their envelopes and thermal contraction. Mass loss is assumed to occur through XUV-driven atmospheric escape and the following Roche-lobe overflow. The runaway effect of mass loss results in a dichotomy of populations: hot Jupiters that retain theirmore » envelopes and super Earths whose envelopes are completely lost. Evolution primarily depends on the core masses of planets and only slightly on migration history. In hot Jupiters with small cores (≅ 10 Earth masses), runaway atmospheric escape followed by Roche-lobe overflow may create sub-Jupiter deserts, as observed in both mass and radius distributions of planetary populations. Comparing our results with formation scenarios and observed exoplanets populations, we propose that populations of closely orbiting exoplanets are formed by capturing planets at/inside the inner edges of protoplanetary disks and subsequent evaporation of sub-Jupiters.« less
The effects of diffusion in hot subdwarf progenitors from the common envelope channel
NASA Astrophysics Data System (ADS)
Byrne, Conor M.; Jeffery, C. Simon; Tout, Christopher A.; Hu, Haili
2018-04-01
Diffusion of elements in the atmosphere and envelope of a star can drastically alter its surface composition, leading to extreme chemical peculiarities. We consider the case of hot subdwarfs, where surface helium abundances range from practically zero to almost 100 percent. Since hot subdwarfs can form via a number of different evolution channels, a key question concerns how the formation mechanism is connected to the present surface chemistry. A sequence of extreme horizontal branch star models was generated by producing post-common envelope stars from red giants. Evolution was computed with MESA from envelope ejection up to core-helium ignition. Surface abundances were calculated at the zero-age horizontal branch for models with and without diffusion. A number of simulations also included radiative levitation. The goal was to study surface chemistry during evolution from cool giant to hot subdwarf and determine when the characteristic subdwarf surface is established. Only stars leaving the giant branch close to core-helium ignition become hydrogen-rich subdwarfs at the zero-age horizontal branch. Diffusion, including radiative levitation, depletes the initial surface helium in all cases. All subdwarf models rapidly become more depleted than observations allow. Surface abundances of other elements follow observed trends in general, but not in detail. Additional physics is required.
Shuttle APS propellant thermal conditioner study
NASA Technical Reports Server (NTRS)
Fulton, D. L.
1971-01-01
The conditioner design concept selected for evaluation consists of an integral reactor and baffle-type heat exchanger. Heat exchange is accomplished by flowing reactor hot gases past a series of slotted and formed plates, through which the conditioned propellant flows. Heat transfer analysis has resulted in the selection of a reactor hot gas nominal mixture ratio of 1.0, giving a combustion temperature of 1560 F with a hydrogen inlet temperature of 275 R. Worst case conditions result in a combustion gas temperature of 2060 F, satisfying the condition of no damage to the conditioner in case of failure to flow cold fluid. In addition, evaluation of hot gas flow requirements and conditioner weight has resulted in the selection of a reactor hot gas exhaust temperature of 750 R.
Disentangling hot Jupiters formation location from their chemical composition
NASA Astrophysics Data System (ADS)
Ali-Dib, Mohamad
2017-05-01
We use a population synthesis model that includes pebbles and gas accretion, planetary migration and a simplified chemistry scheme to study the formation of hot Jupiters. Models have been proposed that these planets can either originate beyond the snowline and then move inwards via disc migration, or form 'in situ' inside the snowline. The goal of this work is to verify which of these two scenarios is more compatible with pebble accretion, and whether we can distinguish observationally between them via the resulting planetary C/O ratios and core masses. Our results show that for Solar system composition, the C/O ratios will vary but moderately between the two populations, since a significant amount of carbon and oxygen is locked up in refractories. In this case, we find a strong correlation between the carbon and oxygen abundances and core mass. The C/O ratio variations are more pronounced in the case where we assume that all carbon and oxygen are in volatiles. On average, hot Jupiters forming 'in situ' inside the snowline will have higher C/O ratios because they accrete less water ice. However, only hot Jupiters forming in situ around stars with C/O = 0.8 can have a C/O ratio higher than unity. We finally find that even with fast pebble accretion, it is significantly easier to form hot Jupiters outside of the snowline, even if forming these 'in situ' is not impossible in the limit of the simplifying assumptions made.
Soman toxicity during and after exposure to different environmental temperatures.
Wheeler, T G
1989-01-01
A systematic study has been conducted to determine physiological susceptibility to the potent anticholinesterase soman during and after exposure to different environmental temperatures. Rats were placed in an environmental chamber set at -1, 7, 15, 23, or 31 degrees C (80% relative humidity, RH) from 0000 to 0800 h. Soman injections were given subcutaneously (sc) at 0600 h (during thermal stress), or at 0810 h after removal from the chamber (injected and tested at 23 degrees C, 60% RH). The measures (taken 30 min after soman injection) included core temperature, grip strength, general state of health, and LD10 estimates (taken 2 h post injection). Soman exposure produced a dose-related effect on each measure under all thermal stress conditions. During thermal stress, soman exposure produced major changes in core temperature ranging from 26 to 41 degrees C, which were linearly related to the environmental temperature condition. After removal from the chamber, soman exposure reduced core temperature by only 1 degree C without regard to prior thermal stress temperature. Grip strength and subjective health rating were soman dose-related with only a minor chamber temperature influence. The toxicity of soman was increased during exposure to either cold or hot environments and after removal from the cold environments. The adrenal-cortical stress response to cold involves increased metabolism and oxygen requirement. The exception was the decreased toxicity observed when soman exposure occurred after removal from a hot environment, exacerbated by a failure in the respiratory system due to anticholinesterase exposure. The increased toxicity of soman while in or after removal from a cold environment is believed to be due to a generalized adrenal-cortical stress response. The increased soman toxicity while in a hot environment, but decreased toxicity after removal from the hot environment, provides an interesting subject for further research.
Horizontal baffle for nuclear reactors
Rylatt, John A.
1978-01-01
A horizontal baffle disposed in the annulus defined between the core barrel and the thermal liner of a nuclear reactor thereby physically separating the outlet region of the core from the annular area below the horizontal baffle. The horizontal baffle prevents hot coolant that has passed through the reactor core from thermally damaging apparatus located in the annulus below the horizontal baffle by utilizing the thermally induced bowing of the horizontal baffle to enhance sealing while accommodating lateral motion of the baffle base plate.
Nielsen, Patricia Switten; Riber-Hansen, Rikke; Schmidt, Henrik; Steiniche, Torben
2016-04-09
Staging of melanoma includes quantification of a proliferation index, i.e., presumed melanocytic mitoses of H&E stains are counted manually in hot spots. Yet, its reproducibility and prognostic impact increases by immunohistochemical dual staining for phosphohistone H3 (PHH3) and MART1, which also may enable fully automated quantification by image analysis. To ensure manageable workloads and repeatable measurements in modern pathology, the study aimed to present an automated quantification of proliferation with automated hot-spot selection in PHH3/MART1-stained melanomas. Formalin-fixed, paraffin-embedded tissue from 153 consecutive stage I/II melanoma patients was immunohistochemically dual-stained for PHH3 and MART1. Whole slide images were captured, and the number of PHH3/MART1-positive cells was manually and automatically counted in the global tumor area and in a manually and automatically selected hot spot, i.e., a fixed 1-mm(2) square. Bland-Altman plots and hypothesis tests compared manual and automated procedures, and the Cox proportional hazards model established their prognostic impact. The mean difference between manual and automated global counts was 2.9 cells/mm(2) (P = 0.0071) and 0.23 cells per hot spot (P = 0.96) for automated counts in manually and automatically selected hot spots. In 77 % of cases, manual and automated hot spots overlapped. Fully manual hot-spot counts yielded the highest prognostic performance with an adjusted hazard ratio of 5.5 (95 % CI, 1.3-24, P = 0.024) as opposed to 1.3 (95 % CI, 0.61-2.9, P = 0.47) for automated counts with automated hot spots. The automated index and automated hot-spot selection were highly correlated to their manual counterpart, but altogether their prognostic impact was noticeably reduced. Because correct recognition of only one PHH3/MART1-positive cell seems important, extremely high sensitivity and specificity of the algorithm is required for prognostic purposes. Thus, automated analysis may still aid and improve the pathologists' detection of mitoses in melanoma and possibly other malignancies.
ALMA Images of the Orion Hot Core at 349 GHz
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wright, M. C. H.; Plambeck, R. L., E-mail: wright@astro.berkeley.edu
We present ALMA images of the dust and molecular line emission in the Orion Hot Core at 349 GHz. At 0.″2 angular resolution the images reveal multiple clumps in an arc ∼1″ east of Orion Source I, the protostar at the center of the Kleinmann–Low Nebula, and another chain of peaks from IRc7 toward the southwest. The molecular line images show narrow filamentary structures at velocities >10 km s{sup −1} away from the heavily resolved ambient cloud velocity ∼5 km s{sup −1}. Many of these filaments trace the SiO outflow from Source I, and lie along the edges of themore » dust emission. Molecular line emission at excitation temperatures 300–2000 K, and velocities >10 km s{sup −1} from the ambient cloud, suggest that the Hot Core may be heated in shocks by the outflow from Source I or from the Becklin–Neugebauer (BN)/SrcI explosion. The spectral line observations also reveal a remarkable molecular ring, ∼2″ south of SrcI, with a diameter ∼600 au. The ring is seen in high-excitation transitions of HC{sub 3}N, HCN v 2 = 1, and SO{sub 2}. An impact of ejecta from the BN/SrcI explosion with a dense dust clump could result in the observed ring of shocked material.« less
The hottest lavas of the Phanerozoic from a reservoir at the core-mantle boundary
NASA Astrophysics Data System (ADS)
Gazel, E.; Trela, J.; Sobolev, A. V.; Bizimis, M.; Jicha, B. R.; Batanova, V. G.
2017-12-01
Petrologic models suggest that modern plume-derived melts generate at high mantle temperatures (>1500 °C) relative to those produced at ambient mid-ocean ridge conditions ( 1350 °C). Earth's mantle has cooled during its history due to heat loss and decrease in radioactive heat production, thus the temperatures of these modern-day basalts are substantially lower than those produced during the Archean (>2.5 Ga), as recorded by komatiites (>1700 °C). Surprisingly, we discovered that the 90 Ma Galapagos-related Tortugal Suite accreted in Costa Rica not only records mantle potential temperatures as high as ancient Archean komatiites ( 1800 °C), but also the highest olivine-spinel crystallization temperatures ever reported ( 1600 °C). These new results from Tortugal (and other anomalously hot Phanerozoic locations) imply that if the mantle is still producing melts as hot as during the Archean, then there must exist reservoirs that preserve Archean temperatures at the base of the lower mantle. These anomalously hot reservoirs could be sustained over time by the steady-state temperature conditions at the core-mantle boundary buffered by the crystallization of Earth's core. Although our results suggest that even modern plumes can produce melts at similar P-T conditions as inferred during the Archean, these occurrences are not common as plumes will likely interact with the cooler ambient mantle.
METHOD FOR MAKING FUEL ELEMENTS
Kates, L.W.; Campbell, R.W.; Heartel, R.H.W.
1960-08-01
A method is given for making zirconium-clad uranium wire. A tube of zirconium is closed with a zirconium plug, after which a chilled uranium core is inserted in the tube to rest against the plug. Additional plugs and cores are inserted alternately as desired. The assembly is then sheathed with iron, hot worked to the desired size, and the iron sheath removed.
Black pepper constituent piperine: genotoxicity studies in vitro and in vivo.
Thiel, Anette; Buskens, Carin; Woehrle, Tina; Etheve, Stéphane; Schoenmakers, Ankie; Fehr, Markus; Beilstein, Paul
2014-04-01
Piperine is responsible for the hot taste of black pepper. Publications on genotoxicity of piperine are reported: negative Ames Tests and one in vitro micronucleus test (MNT). In vivo tests were mainly negative. In the majority of the data the administered dose levels did not follow the dose selection requirements of regulatory guidelines of having dose levels up to the maximum tolerated dose (MTD). The only oral high dose studies were a positive in vivo MNT in mice in contrast to a negative in vivo chromosome aberration test in rats. Thus, conflicting results in genotoxicity testing are published. To investigate this further, we administered piperine to mice up to the MTD and determined micronuclei-frequency. Piperine reduces core body temperature and interferes with blood cells both being known to result in irrelevant positive in vivo MNTs. Therefore we added mechanistic endpoints: core body temperature, haematology, erythropoietin level, and organ weights. Additionally an in vitro MNT in Chinese hamster ovary cells was performed. Piperine was negative in the in vitro MNT. It caused significant reduction of core body temperature, decrease of white blood cells and spleen weights but no increase in the micronucleus-frequency. Thus, in our studies piperine was not genotoxic. Copyright © 2014 Elsevier Ltd. All rights reserved.
Galaxy And Mass Assembly (GAMA): the effect of galaxy group environment on active galactic nuclei
NASA Astrophysics Data System (ADS)
Gordon, Yjan A.; Pimbblet, Kevin A.; Owers, Matt S.; Bland-Hawthorn, Joss; Brough, Sarah; Brown, Michael J. I.; Cluver, Michelle E.; Croom, Scott M.; Holwerda, Benne W.; Loveday, Jonathan; Mahajan, Smriti; Wang, Lingyu
2018-04-01
In galaxy clusters, efficiently accreting active galactic nuclei (AGNs) are preferentially located in the infall regions of the cluster projected phase-space, and are rarely found in the cluster core. This has been attributed to both an increase in triggering opportunities for infalling galaxies, and a reduction of those mechanisms in the hot, virialized, cluster core. Exploiting the depth and completeness (98 per cent at r < 19.8 mag) of the Galaxy And Mass Assembly survey (GAMA), we probe down the group halo mass function to assess whether AGNs are found in the same regions in groups as they are in clusters. We select 451 optical AGNs from 7498 galaxies with log10(M*/M⊙) > 9.9 in 695 groups with 11.53 ≤ log10(M200/M⊙) ≤ 14.56 at z < 0.15. By analysing the projected phase-space positions of these galaxies, we demonstrate that when split both radially, and into physically derived infalling and core populations, AGN position within group projected phase-space is dependent on halo mass. For groups with log10(M200/M⊙) > 13.5, AGNs are preferentially found in the infalling galaxy population with 3.6σ confidence. At lower halo masses, we observe no difference in AGN fraction between core and infalling galaxies. These observations support a model where a reduced number of low-speed interactions, ram pressure stripping and intra-group/cluster medium temperature, the dominance of which increase with halo mass, work to inhibit AGN in the cores of groups and clusters with log10(M200/M⊙) > 13.5, but do not significantly affect nuclear activity in cores of less massive structures.
Plasma Heating and Flow in an Auroral Arc
NASA Technical Reports Server (NTRS)
Moore, T. E.; Chandler, M. O.; Pollock, C. J.; Reasoner, D. L.; Arnoldy, R. L.; Austin, B.; Kintner, P. M.; Bonnell, J.
1996-01-01
We report direct observations of the three-dimensional velocity distribution of selected topside ionospheric ion species in an auroral context between 500 and 550 km altitude. We find heating transverse to the local magnetic field in the core plasma, with significant heating of 0(+), He(+), and H(+), as well as tail heating events that occur independently of the core heating. The 0(+) velocity distribution departs from bi-Maxwellian, at one point exhibiting an apparent ring-like shape. However, these observations are shown to be aliased within the auroral arc by temporal variations that arc not well-resolved by the core plasma instrument. The dc electric field measurements reveal superthermal plasma drifts that are consistent with passage of the payload through a series of vortex structures or a larger scale circularly polarized hydromagnetic wave structure within the auroral arc. The dc electric field also shows that impulsive solitary structures, with a frequency spectrum in the ion cyclotron frequency range, occur in close correlation with the tail heating events. The drift and core heating observations lend support to the idea that core ion heating is driven at low altitudes by rapid convective motions imposed by the magnetosphere. Plasma wave emissions at ion frequencies and parallel heating of the low-energy electron plasma are observed in conjunction with this auroral form; however, the conditions are much more complex than those typically invoked in previous theoretical treatments of superthermal frictional heating. The observed ion heating within the arc clearly exceeds that expected from frictional heating for the light ion species H(+) and He(+), and the core distributions also contain hot transverse tails, indicating an anomalous transverse heat source.
Evolution Models of Helium White Dwarf–Main-sequence Star Merger Remnants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Xianfei; Bi, Shaolan; Hall, Philip D.
It is predicted that orbital decay by gravitational-wave radiation and tidal interaction will cause some close binary stars to merge within a Hubble time. The merger of a helium-core white dwarf with a main-sequence (MS) star can produce a red giant branch star that has a low-mass hydrogen envelope when helium is ignited and thus become a hot subdwarf. Because detailed calculations have not been made, we compute post-merger models with a stellar evolution code. We find the evolutionary paths available to merger remnants and find the pre-merger conditions that lead to the formation of hot subdwarfs. We find thatmore » some such mergers result in the formation of stars with intermediate helium-rich surfaces. These stars later develop helium-poor surfaces owing to diffusion. Combining our results with a model population and comparing to observed stars, we find that some observed intermediate helium-rich hot subdwarfs can be explained as the remnants of the mergers of helium-core white dwarfs with low-mass MS stars.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hussain, Azam; Zhao, Zhenling; Xie, Jinlin, E-mail: jlxie@ustc.edu.cn
The spatial and temporal evolutions of compound sawteeth were directly observed using 2D electron cyclotron emission imaging on experimental advanced superconducting tokamak. The compound sawtooth consists of partial and full collapses. After partial collapse, the hot core survives as only a small amount of heat disperses outwards, whereas in the following full collapse a large amount of heat is released and the hot core dissipates. The presence of two q = 1 surfaces was not observed. Instead, the compound sawtooth occurs mainly at the beginning of an ion cyclotron resonant frequency heating pulse and during the L-H transition phase, which may bemore » related to heat transport suppression caused by a decrease in electron heat diffusivity.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fan, Lulu; Gao, Ying; Zhang, Dandan
Previous studies have shown that Wide-field Infrared Survey Explorer -selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ∼ 3 using Hubble Space Telescope /WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, whichmore » suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (∼10{sup 14} L {sub ⊙}) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.« less
A feature-based approach to modeling protein-protein interaction hot spots.
Cho, Kyu-il; Kim, Dongsup; Lee, Doheon
2009-05-01
Identifying features that effectively represent the energetic contribution of an individual interface residue to the interactions between proteins remains problematic. Here, we present several new features and show that they are more effective than conventional features. By combining the proposed features with conventional features, we develop a predictive model for interaction hot spots. Initially, 54 multifaceted features, composed of different levels of information including structure, sequence and molecular interaction information, are quantified. Then, to identify the best subset of features for predicting hot spots, feature selection is performed using a decision tree. Based on the selected features, a predictive model for hot spots is created using support vector machine (SVM) and tested on an independent test set. Our model shows better overall predictive accuracy than previous methods such as the alanine scanning methods Robetta and FOLDEF, and the knowledge-based method KFC. Subsequent analysis yields several findings about hot spots. As expected, hot spots have a larger relative surface area burial and are more hydrophobic than other residues. Unexpectedly, however, residue conservation displays a rather complicated tendency depending on the types of protein complexes, indicating that this feature is not good for identifying hot spots. Of the selected features, the weighted atomic packing density, relative surface area burial and weighted hydrophobicity are the top 3, with the weighted atomic packing density proving to be the most effective feature for predicting hot spots. Notably, we find that hot spots are closely related to pi-related interactions, especially pi . . . pi interactions.
Aerodynamics inside a rapid compression machine
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mittal, Gaurav; Sung, Chih-Jen
2006-04-15
The aerodynamics inside a rapid compression machine after the end of compression is investigated using planar laser-induced fluorescence (PLIF) of acetone. To study the effect of reaction chamber configuration on the resulting aerodynamics and temperature field, experiments are conducted and compared using a creviced piston and a flat piston under varying conditions. Results show that the flat piston design leads to significant mixing of the cold vortex with the hot core region, which causes alternate hot and cold regions inside the combustion chamber. At higher pressures, the effect of the vortex is reduced. The creviced piston head configuration is demonstratedmore » to result in drastic reduction of the effect of the vortex. Experimental conditions are also simulated using the Star-CD computational fluid dynamics package. Computed results closely match with experimental observation. Numerical results indicate that with a flat piston design, gas velocity after compression is very high and the core region shrinks quickly due to rapid entrainment of cold gases. Whereas, for a creviced piston head design, gas velocity after compression is significantly lower and the core region remains unaffected for a long duration. As a consequence, for the flat piston, adiabatic core assumption can significantly overpredict the maximum temperature after the end of compression. For the creviced piston, the adiabatic core assumption is found to be valid even up to 100 ms after compression. This work therefore experimentally and numerically substantiates the importance of piston head design for achieving a homogeneous core region inside a rapid compression machine. (author)« less
Antifreeze in the hot core of Orion. First detection of ethylene glycol in Orion-KL
NASA Astrophysics Data System (ADS)
Brouillet, N.; Despois, D.; Lu, X.-H.; Baudry, A.; Cernicharo, J.; Bockelée-Morvan, D.; Crovisier, J.; Biver, N.
2015-04-01
Context. Ices are present in comets and in the mantles of interstellar grains. Their chemical composition has been indirectly derived by observing molecules released in the gas phase, when comets approach the sun and when ice mantles are sublimated or destroyed, e.g. in the hot cores present in high-mass, star-forming regions. Comparison of these chemical compositions sheds light on the formation of comets and on the evolution of interstellar matter from the molecular cloud to a protoplanetary disk, and it shows, to first order, a good agreement between the cometary and interstellar abundances. However, a complex O-bearing organic molecule, ethylene glycol (CH2OH)2, seems to depart from this correlation because it was not easily detected in the interstellar medium (Sgr B2) although it proved to be rather abundant with respect to other O-bearing species in comet C/1995 O1 (Hale-Bopp). Ethylene glycol thus appears, together with the closely related molecules glycolaldehyde CH2OHCHO and ethanol CH3CH2OH, as a key species in the comparison of interstellar and cometary ices as well as in any discussion on the formation of cometary matter. Aims: It is important to measure the molecular abundances in various hot cores to see if the observed differences between the interstellar medium and the comets are general. We focus here on the analysis of ethylene glycol in the nearest and best studied hot core-like region, Orion-KL. Methods: We use ALMA interferometric data because high spatial resolution observations allow us to reduce the line confusion problem with respect to single-dish observations since different molecules are expected to exhibit different spatial distributions. Furthermore, a large spectral bandwidth is needed because many individual transitions are required to securely detect large organic molecules. Confusion and continuum subtraction are major issues and have been handled with care. Results: We have detected the aGg' conformer of ethylene glycol in Orion-KL. The emission is compact and peaks towards the hot core close to the main continuum peak, about 2″ to the south-west; this distribution is notably different from other O-bearing species. Assuming optically thin lines and local thermodynamic equilibrium, we derive a rotational temperature of 145 ± 30 K and a column density of 4.6 ± 0.8 × 1015 cm-2. The limit on the column density of the gGg' conformer is five times lower. Based on observations carried out with ALMA and the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).Appendix A is available in electronic form at http://www.aanda.org
NASA Astrophysics Data System (ADS)
Losso, C.; Arizzi Novelli, A.; Picone, M.; Marchetto, D.; Pessa, G.; Molinaroli, E.; Ghetti, P. F.; Volpi Ghirardini, A.
2004-11-01
Toxic hazard in sites with varying types and levels of contamination in the Lagoon of Venice was estimated by means of toxicity bioassays based on the early life-stages of the autochthonous sea urchin Paracentrotus lividus. Elutriate was chosen as the test matrix, due to its ability to highlight potential toxic effects towards sensitive biological components of the water column caused by sediment resuspension phenomena affecting the Lagoon. Surficial sediments (core-top 5 cm deep), directly influenced by resuspension/redeposition processes, and core sediments (core 20 cm deep), recording time-mediated contamination, were sampled in some sites located in the lagoonal area most greatly influenced by anthropogenic activities. Particle size, organic matter and water content were also analysed. In two sites, the results of physical parameters showed that the core-top sediments were coarser than the 20-cm core sediments. Sperm cell toxicity test results showed the negligible acute toxicity of elutriates from all investigated sites. The embryo toxicity test demonstrated a short-term chronic toxicity gradient for elutriates from the 20-cm core sediments, in general agreement both with the expected contamination gradient and with results of the Microtox® solid-phase test. Elutriates of the core-top 5-cm sediments revealed a totally inverted gradient, in comparison with that for the 20-cm core sediments, and the presence of a "hot spot" of contamination in the site chosen as a possible reference. Investigations on ammonia and sulphides as possible confounding factors excluded their contribution to this "hot spot". Integrated physico-chemical and toxicity results on sediments at various depths demonstrated the presence of disturbed sediments in the central basin of the Lagoon of Venice.
Planet traps and first planets: The critical metallicity for gas giant formation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hasegawa, Yasuhiro; Hirashita, Hiroyuki, E-mail: yasu@asiaa.sinica.edu.tw, E-mail: hirashita@asiaa.sinica.edu.tw
2014-06-10
The ubiquity of planets poses an interesting question: when are first planets formed in galaxies? We investigate this by adopting a theoretical model where planet traps are combined with the standard core accretion scenario in which the efficiency of forming planetary cores directly relates to the metallicity ([Fe/H]) in disks. Three characteristic exoplanetary populations are examined: hot Jupiters, exo-Jupiters around 1 AU, and low-mass planets in tight orbits, such as super-Earths. We statistically compute planet formation frequencies (PFFs), as well as the orbital radius (〈R{sub rapid}〉) within which gas accretion becomes efficient enough to form Jovian planets, as a functionmore » of metallicity (–2 ≤ [Fe/H] ≤–0.6). We show that the total PFFs for these three populations increase steadily with metallicity. This is the direct outcome of the core accretion picture. For the metallicity range considered here, the population of low-mass planets dominates Jovian planets. The Jovian planets contribute to the PFFs above [Fe/H] ≅ –1. We find that the hot Jupiters form more efficiently than the exo-Jupiters at [Fe/H] ≲ –0.7. This arises from the slower growth of planetary cores and their more efficient radial inward transport by the host traps in lower metallicity disks. We show that the critical metallicity for forming Jovian planets is [Fe/H] ≅ –1.2 by comparing 〈R{sub rapid}〉 of hot Jupiters and low-mass planets. The comparison intrinsically links to the different gas accretion efficiency between these two types of planets. Therefore, this study implies that important physical processes in planet formation may be tested by exoplanet observations around metal-poor stars.« less
Application of induction coil measurements to the study of superalloy hot corrosion and oxidation
NASA Technical Reports Server (NTRS)
Deadmore, D. L.
1984-01-01
The assessment of the degree of hot corrosion attack on nickel based alloys is a difficult task, especially when the definition specifies that it must be in terms of metal consumed and even more difficult if the measurement must be nondestructive. The inductance of a solenoid coil responds to changes in volume of fill and composition of metal cores, therefore, it may be used for nondestructive measurement of hot corrosion. The hot corrosion of U700 was studied at 900 C in a Mach 0.3 flame doped with 0.85 wppm of sodium. The change of inductance was found to define the known corrosion behavior and to suggest its use as a tool with predictive capabilities. Sufficient sensitivity exists to detect oxidation of this alloy at 900 C.
Han, Wooseok; Menezes, Daniel L; Xu, Yongjin; Knapp, Mark S; Elling, Robert; Burger, Matthew T; Ni, Zhi-Jie; Smith, Aaron; Lan, Jiong; Williams, Teresa E; Verhagen, Joelle; Huh, Kay; Merritt, Hanne; Chan, John; Kaufman, Susan; Voliva, Charles F; Pecchi, Sabina
2016-02-01
Alterations in PI3K/AKT signaling are known to be implicated with tumorigenesis. The PI3 kinases family of lipid kinases has been an attractive therapeutic target for cancer treatment. Imidazopyridine compound 1, a potent, selective, and orally available pan-PI3K inhibitor, identified by scaffold morphing of a benzothiazole hit, was further optimized in order to achieve efficacy in a PTEN-deleted A2780 ovarian cancer mouse xenograft model. With a hypothesis that a planar conformation between the core and the 6-heteroaryl ring will allow for the accommodation of larger 5'-substituents in a hydrophobic area under P-loop, SAR efforts focused on 5'-alkoxy heteroaryl rings at the 6-position of imidazopyridine and imidazopyridazine cores that have the same dihedral angle of zero degrees. 6'-Alkoxy 5'-aminopyrazines in the imidazopyridine series were identified as the most potent compounds in the A2780 cell line. Compound 14 with 1,1,1-trifluoroisopropoxy group at 6'-position demonstrated excellent potency and selectivity, good oral exposure in rats and in vivo efficacy in A2780 tumor-bearing mouse. Also, we disclose the X-ray co-crystal structure of one enantiomer of compound 14 in PI3Kα, confirming that the trifluoromethyl group fits nicely in the hydrophobic hot spot under P-loop. Copyright © 2016 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Han, Wooseok; Menezes, Daniel L.; Xu, Yongjin
Alterations in PI3K/AKT signaling are known to be implicated with tumorigenesis. The PI3 kinases family of lipid kinases has been an attractive therapeutic target for cancer treatment. Imidazopyridine compound 1, a potent, selective, and orally available pan-PI3K inhibitor, identified by scaffold morphing of a benzothiazole hit, was further optimized in order to achieve efficacy in a PTEN-deleted A2780 ovarian cancer mouse xenograft model. With a hypothesis that a planar conformation between the core and the 6-heteroaryl ring will allow for the accommodation of larger 5'-substituents in a hydrophobic area under P-loop, SAR efforts focused on 5'-alkoxy heteroaryl rings at themore » 6-position of imidazopyridine and imidazopyridazine cores that have the same dihedral angle of zero degrees. 6'-Alkoxy 5'-aminopyrazines in the imidazopyridine series were identified as the most potent compounds in the A2780 cell line. Compound 14 with 1,1,1-trifluoroisopropoxy group at 6'-position demonstrated excellent potency and selectivity, good oral exposure in rats and in vivo efficacy in A2780 tumor-bearing mouse. Also, we disclose the X-ray co-crystal structure of one enantiomer of compound 14 in PI3Kα, confirming that the trifluoromethyl group fits nicely in the hydrophobic hot spot under P-loop.« less
Cause and Effect of Feedback: Multiphase Gas in Cluster Cores Heated by AGN Jets
NASA Astrophysics Data System (ADS)
Gaspari, M.; Ruszkowski, M.; Sharma, P.
2012-02-01
Multiwavelength data indicate that the X-ray-emitting plasma in the cores of galaxy clusters is not cooling catastrophically. To a large extent, cooling is offset by heating due to active galactic nuclei (AGNs) via jets. The cool-core clusters, with cooler/denser plasmas, show multiphase gas and signs of some cooling in their cores. These observations suggest that the cool core is locally thermally unstable while maintaining global thermal equilibrium. Using high-resolution, three-dimensional simulations we study the formation of multiphase gas in cluster cores heated by collimated bipolar AGN jets. Our key conclusion is that spatially extended multiphase filaments form only when the instantaneous ratio of the thermal instability and free-fall timescales (t TI/t ff) falls below a critical threshold of ≈10. When this happens, dense cold gas decouples from the hot intracluster medium (ICM) phase and generates inhomogeneous and spatially extended Hα filaments. These cold gas clumps and filaments "rain" down onto the central regions of the core, forming a cold rotating torus and in part feeding the supermassive black hole. Consequently, the self-regulated feedback enhances AGN heating and the core returns to a higher entropy level with t TI/t ff > 10. Eventually, the core reaches quasi-stable global thermal equilibrium, and cold filaments condense out of the hot ICM whenever t TI/t ff <~ 10. This occurs despite the fact that the energy from AGN jets is supplied to the core in a highly anisotropic fashion. The effective spatial redistribution of heat is enabled in part by the turbulent motions in the wake of freely falling cold filaments. Increased AGN activity can locally reverse the cold gas flow, launching cold filamentary gas away from the cluster center. Our criterion for the condensation of spatially extended cold gas is in agreement with observations and previous idealized simulations.
NASA Astrophysics Data System (ADS)
López-Sepulcre, A.; Sakai, N.; Neri, R.; Imai, M.; Oya, Y.; Ceccarelli, C.; Higuchi, A. E.; Aikawa, Y.; Bottinelli, S.; Caux, E.; Hirota, T.; Kahane, C.; Lefloch, B.; Vastel, C.; Watanabe, Y.; Yamamoto, S.
2017-10-01
Context. Hot corinos are extremely rich in complex organic molecules (COMs). Accurate abundance measurements of COMs in such objects are crucial to constrain astrochemical models. In the particular case of close binary systems this can only be achieved through high angular resolution imaging. Aims: We aim to perform an interferometric study of multiple COMs in NGC 1333 IRAS 4A, which is a protostellar binary hosting hot corino activity, at an angular resolution that is sufficient to distinguish easily the emission from the two cores separated by 1.8''. Methods: We used the Atacama Large (sub-)Millimeter Array (ALMA) in its 1.2 mm band and the IRAM Plateau de Bure Interferometer (PdBI) at 2.7 mm to image, with an angular resolution of 0.5'' (120 au) and 1'' (235 au), respectively, the emission from 11 different organic molecules in IRAS 4A. This allowed us to clearly disentangle A1 and A2, the two protostellar cores. For the first time, we were able to derive the column densities and fractional abundances simultaneously for the two objects, allowing us to analyse the chemical differences between them. Results: Molecular emission from organic molecules is concentrated exclusively in A2, while A1 appears completely devoid of COMs or even simpler organic molecules, such as HNCO, even though A1 is the strongest continuum emitter. The protostellar core A2 displays typical hot corino abundances and its deconvolved size is 70 au. In contrast, the upper limits we placed on COM abundances for A1 are extremely low, lying about one order of magnitude below prestellar values. The difference in the amount of COMs present in A1 and A2 ranges between one and two orders of magnitude. Our results suggest that the optical depth of dust emission at these wavelengths is unlikely to be sufficiently high to completely hide a hot corino in A1 similar in size to that in A2. Thus, the significant contrast in molecular richness found between the two sources is most probably real. We estimate that the size of a hypothetical hot corino in A1 should be less than 12 au. Conclusions: Our results favour a scenario in which the protostar in A2 is either more massive and/or subject to a higher accretion rate than A1, as a result of inhomogeneous fragmentation of the parental molecular clump. This naturally explains the smaller current envelope mass in A2 with respect to A1 along with its molecular richness. The extremely low abundances of organic molecules in A1 with respect to those in A2 demonstrate that the dense inner regions of a young protostellar core lacking hot corino activity may be poorer in COMs than the outer protostellar envelope. The reduced datacube is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/606/A121
ALCHEMIC: Advanced time-dependent chemical kinetics
NASA Astrophysics Data System (ADS)
Semenov, Dmitry A.
2017-08-01
ALCHEMIC solves chemical kinetics problems, including gas-grain interactions, surface reactions, deuterium fractionization, and transport phenomena and can model the time-dependent chemical evolution of molecular clouds, hot cores, corinos, and protoplanetary disks.
Finfrock, Christopher B.; Exil, Andrea; Carroll, Jay D.; ...
2018-06-06
AlSi10Mg tensile bars were additively manufactured using the powder-bed selective laser melting process. Samples were subjected to stress relief annealing and hot isostatic pressing. Tensile samples built using fresh, stored, and reused powder feedstock were characterized for microstructure, porosity, and mechanical properties. Fresh powder exhibited the best mechanical properties and lowest porosity while stored and reused powder exhibited inferior mechanical properties and higher porosity. The microstructure of stress relieved samples was fine and exhibited (001) texture in the z-build direction. Microstructure for hot isostatic pressed samples was coarsened with fainter (001) texture. To investigate surface and interior defects, scanning electronmore » microscopy, optical fractography, and laser scanning microscopy techniques were employed. Hot isostatic pressing eliminated internal pores and reduced the size of surface porosity associated with the selective laser melting process. Hot isostatic pressing tended to increase ductility at the expense of decreasing strength. Furthermore, scatter in ductility of hot isostatic pressed parts suggests that the presence of unclosed surface porosity facilitated fracture with crack propagation inward from the surface of the part.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Finfrock, Christopher B.; Exil, Andrea; Carroll, Jay D.
AlSi10Mg tensile bars were additively manufactured using the powder-bed selective laser melting process. Samples were subjected to stress relief annealing and hot isostatic pressing. Tensile samples built using fresh, stored, and reused powder feedstock were characterized for microstructure, porosity, and mechanical properties. Fresh powder exhibited the best mechanical properties and lowest porosity while stored and reused powder exhibited inferior mechanical properties and higher porosity. The microstructure of stress relieved samples was fine and exhibited (001) texture in the z-build direction. Microstructure for hot isostatic pressed samples was coarsened with fainter (001) texture. To investigate surface and interior defects, scanning electronmore » microscopy, optical fractography, and laser scanning microscopy techniques were employed. Hot isostatic pressing eliminated internal pores and reduced the size of surface porosity associated with the selective laser melting process. Hot isostatic pressing tended to increase ductility at the expense of decreasing strength. Furthermore, scatter in ductility of hot isostatic pressed parts suggests that the presence of unclosed surface porosity facilitated fracture with crack propagation inward from the surface of the part.« less
A feature-based approach to modeling protein–protein interaction hot spots
Cho, Kyu-il; Kim, Dongsup; Lee, Doheon
2009-01-01
Identifying features that effectively represent the energetic contribution of an individual interface residue to the interactions between proteins remains problematic. Here, we present several new features and show that they are more effective than conventional features. By combining the proposed features with conventional features, we develop a predictive model for interaction hot spots. Initially, 54 multifaceted features, composed of different levels of information including structure, sequence and molecular interaction information, are quantified. Then, to identify the best subset of features for predicting hot spots, feature selection is performed using a decision tree. Based on the selected features, a predictive model for hot spots is created using support vector machine (SVM) and tested on an independent test set. Our model shows better overall predictive accuracy than previous methods such as the alanine scanning methods Robetta and FOLDEF, and the knowledge-based method KFC. Subsequent analysis yields several findings about hot spots. As expected, hot spots have a larger relative surface area burial and are more hydrophobic than other residues. Unexpectedly, however, residue conservation displays a rather complicated tendency depending on the types of protein complexes, indicating that this feature is not good for identifying hot spots. Of the selected features, the weighted atomic packing density, relative surface area burial and weighted hydrophobicity are the top 3, with the weighted atomic packing density proving to be the most effective feature for predicting hot spots. Notably, we find that hot spots are closely related to π–related interactions, especially π · · · π interactions. PMID:19273533
NASA Astrophysics Data System (ADS)
Udintsev, V. S.; Ottaviani, M.; Maget, P.; Giruzzi, G.; Ségui, J.-L.; Aniel, T.; Artaud, J. F.; Clairet, F.; Goniche, M.; Hoang, G. T.; Huysmans, G. T. A.; Imbeaux, F.; Joffrin, E.; Mazon, D.; Pecquet, A. L.; Sabot, R.; Sirinelli, A.; Vermare, L.; Tore Supra Team; Krämer-Flecken, A.; Koslowski, H. R.; TEXTOR Team; Donné, A. J. H.; Schüller, F. C.; Domier, C. W.; Luhmann, N. C., Jr.; Mirnov, S. V.
2005-08-01
To shed some light on the development of the fast m/n = 1/1 precursor to the sawtooth crash and its influence on plasma transport properties in the vicinity of the q = 1 surface, series of dedicated experiments have been conducted on the Tore Supra and TEXTOR tokamaks. It has been concluded that, before a crash, the hot core gets displaced with respect to the magnetic axis, drifts outwards by as much as 8-10 cm and may change its shape. Observation of the magnetic reconnection process has been made by means of electron cyclotron emission diagnostics. The heat pulse is seen far outside the inversion radius. The colder plasma develops a magnetic island on the former magnetic axis, after the hot core expulsion. Different kinds of behaviour of the m = 1 precursor before the crash, with respect to the displacement of the hot core and the duration of the oscillating phase, have been observed. An ideal kink model alone cannot be used for explanation; therefore, resistive effects play an important role in the mode development. Possible mechanisms that lead an m = 1 mode to such behaviour, and their links to the change in the central q-profile, are discussed. Results have been discussed in the light of various theoretical models of the sawtooth. This is an extended version of the paper presented at the 31st EPS Conf. on Plasma Physics (London, 28 June-2 July 2004).
Spin-orbit coupling and tidal dissipation in hot Jupiter systems
NASA Astrophysics Data System (ADS)
Shabaltas, Natalia Igorevna
Hot Jupiters are giant planets located extremely close to their host stars, with orbital periods less than 5 days. Many aspects of hot Jupiter (HJ) formation remain unclear, but several clues, such as the observed misalignment between their orbital axes and their hosts' spin axes, point to a dynamical origin. In the first portion of this work we explore the stellar spin-orbit dynamics of one such dynamical formation channel, the Lidov-Kozai mechanism. We show that the coupling between the stellar spin and the planet orbit can lead to complex, and sometimes chaotic, behavior of the stellar spin vector. Many features of this behavior arise due to a set of resonances between the stellar spin axis precession timescale and the Lidov-Kozai timescale. Under the assumption that the stellar quadrupole does not induce precession in the planet's orbit, given a system with a set of initial parameters, we show that it is possible to predict whether the system can attain high spin-orbit misalignments. In the second portion of this work, we discuss tidal dissipation in giant planets, another aspect that is crucial to dynamical HJ formation theories. We show that tidal dissipation in the cores of giant planets can be significant, and can help reconcile inconsistencies in the tidal dissipation efficiencies inferred from observations of Jupiter's moons and from high-eccentricity HJ migration theories. Finally, we improve upon existing core tidal dissipation theories by presenting semi-analytical formulae for dissipation in a core surrounded by a polytropic n = 1 envelope.
Complex organic molecules and star formation
NASA Astrophysics Data System (ADS)
Bacmann, A.; Faure, A.
2014-12-01
Star forming regions are characterised by the presence of a wealth of chemical species. For the past two to three decades, ever more complex organic species have been detected in the hot cores of protostars. The evolution of these molecules in the course of the star forming process is still uncertain, but it is likely that they are partially incorporated into protoplanetary disks and then into planetesimals and the small bodies of planetary systems. The complex organic molecules seen in star forming regions are particularly interesting since they probably make up building blocks for prebiotic chemistry. Recently we showed that these species were also present in the cold gas in prestellar cores, which represent the very first stages of star formation. These detections question the models which were until now accepted to account for the presence of complex organic molecules in star forming regions. In this article, we shortly review our current understanding of complex organic molecule formation in the early stages of star formation, in hot and cold cores alike and present new results on the formation of their likely precursor radicals.
Asteroseismic Constraints on the Models of Hot B Subdwarfs: Convective Helium-Burning Cores
NASA Astrophysics Data System (ADS)
Schindler, Jan-Torge; Green, Elizabeth M.; Arnett, W. David
2017-10-01
Asteroseismology of non-radial pulsations in Hot B Subdwarfs (sdB stars) offers a unique view into the interior of core-helium-burning stars. Ground-based and space-borne high precision light curves allow for the analysis of pressure and gravity mode pulsations to probe the structure of sdB stars deep into the convective core. As such asteroseismological analysis provides an excellent opportunity to test our understanding of stellar evolution. In light of the newest constraints from asteroseismology of sdB and red clump stars, standard approaches of convective mixing in 1D stellar evolution models are called into question. The problem lies in the current treatment of overshooting and the entrainment at the convective boundary. Unfortunately no consistent algorithm of convective mixing exists to solve the problem, introducing uncertainties to the estimates of stellar ages. Three dimensional simulations of stellar convection show the natural development of an overshooting region and a boundary layer. In search for a consistent prescription of convection in one dimensional stellar evolution models, guidance from three dimensional simulations and asteroseismological results is indispensable.
DOT National Transportation Integrated Search
2009-01-01
This report summarizes research presented in separate technical reports, papers, and journal articles that collectively document the development of a systematic process to aid in the selection of appropriate bituminous hot-poured sealants for pavemen...
NASA Astrophysics Data System (ADS)
Hogan, M. T.; McNamara, B. R.; Pulido, F. A.; Nulsen, P. E. J.; Vantyghem, A. N.; Russell, H. R.; Edge, A. C.; Babyk, Iu.; Main, R. A.; McDonald, M.
2017-12-01
We present accurate mass and thermodynamic profiles for 57 galaxy clusters observed with the Chandra X-ray Observatory. We investigate the effects of local gravitational acceleration in central cluster galaxies, and explore the role of the local free-fall time ({t}{ff}) in thermally unstable cooling. We find that the radially averaged cooling time ({t}{cool}) is as effective an indicator of cold gas, traced through its nebular emission, as the ratio {t}{cool}/{t}{ff}. Therefore, {t}{cool} primarily governs the onset of thermally unstable cooling in hot atmospheres. The location of the minimum {t}{cool}/{t}{ff}, a thermodynamic parameter that many simulations suggest is key in driving thermal instability, is unresolved in most systems. Consequently, selection effects bias the value and reduce the observed range in measured {t}{cool}/{t}{ff} minima. The entropy profiles of cool-core clusters are characterized by broken power laws down to our resolution limit, with no indication of isentropic cores. We show, for the first time, that mass isothermality and the K\\propto {r}2/3 entropy profile slope imply a floor in {t}{cool}/{t}{ff} profiles within central galaxies. No significant departures of {t}{cool}/{t}{ff} below 10 are found. This is inconsistent with models that assume thermally unstable cooling ensues from linear perturbations at or near this threshold. We find that the inner cooling times of cluster atmospheres are resilient to active galactic nucleus (AGN)-driven change, suggesting gentle coupling between radio jets and atmospheric gas. Our analysis is consistent with models in which nonlinear perturbations, perhaps seeded by AGN-driven uplift of partially cooled material, lead to cold gas condensation.
Aubriot, Xavier; Lowry, Porter P; Cruaud, Corinne; Couloux, Arnaud; Haevermans, Thomas
2013-01-01
The island of Madagascar is a key hot spot for the genus Euphorbia, with at least 170 native species, almost all endemic. Threatened by habitat loss and illegal collection of wild plants, nearly all Malagasy Euphorbia are listed in CITES Appendices I and II. The absence of a reliable taxonomic revision makes it particularly difficult to identify these plants, even when fertile, and thereby compromises the application of CITES regulations. DNA barcoding, which can facilitate species-level identification irrespective of developmental stage and the presence of flowers or fruits, may be a promising tool for monitoring and controlling trade involving threatened species. In this study, we test the potential value of barcoding on 41 Euphorbia species representative of the genus in Madagascar, using the two widely adopted core barcode markers (matK and rbcL), along with two additional DNA regions, nuclear internal transcribed spacer (ITS) and the chloroplastic intergenic spacer psbA-trnH. For each marker and for selected marker combinations, inter- and intraspecific distance estimates and species discrimination rates are calculated. Results using just the 'official' barcoding markers yield overlapping inter- and intraspecific ranges and species discrimination rates below 60%. When ITS is used, whether alone or in combination with the core markers, species discrimination increases to nearly 100%, whereas the addition of psbA-trnH produces less satisfactory results. This study, the first ever to test barcoding on the large, commercially important genus Euphorbia shows that this method could be developed into a powerful identification tool and thereby contribute to more effective application of CITES regulations. © 2012 Blackwell Publishing Ltd.
An astrophysics data program investigation of cluster evolution
NASA Technical Reports Server (NTRS)
Kellogg, Edwin M.
1990-01-01
A preliminary status report is given on studies using the Einstein x ray observations of distant clusters of galaxies that are also candidates for gravitational lenses. The studies will determine the location and surface brightness distribution of the x ray emission from clusters associated with selected gravitational lenses. The x ray emission comes from hot gas that traces out the total gravitational potential in the cluster, so its distribution is approximately the same as the mass distribution causing gravitational lensing. Core radii and x ray virial masses can be computed for several of the brighter Einstein sources, and preliminary results are presented on A2218. Preliminary status is also reported on a study of the optical data from 0024+16. A provisional value of 1800 to 2200 km/s for the equivalent velocity dispersion is obtained. The ultimate objective is to extract the mass of the gravitational lens, and perhaps more detailed information on the distribution of matter as warranted. A survey of the Einstein archive shows that the clusters A520, A1704, 3C295, A2397, A1722, SC5029-247, A3186 and A370 have enough x ray counts observed to warrant more detailed optical observations of arcs for comparison. Mass estimates for these clusters can therefore be obtained from three independent sources: the length scale (core radius) that characterizes the density dropoff of the x ray emitting hot gas away from its center, the velocity dispersion of the galaxies moving in the cluster potential, and gravitational bending of light by the total cluster mass. This study will allow the comparison of these three techniques and ultimately improve the knowledge of cluster masses.
EDF experience with {open_quotes}hot spot{close_quotes} management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Guio, J.M. de
1995-03-01
During the past few years, {open_quotes}hot spots{close_quotes} due to the presence of particles of metal activated during their migration through the reactor core, have been detected at several French pressurized water reactor (PWR) units. These {open_quotes}hot spots,{close_quotes} which generate very high dose rates (from about 10 Gy/h to 200 G/h) are a significant factor in increase occupational exposures during outrates. Of particular concern are the difficult cases which prolong outage duration and increase the volume of radiological waste. Confronted with this situation, Electricite de France (EDF) has set up a national research group, as part of its ALARA program, tomore » establish procedures and techniques to avoid, detect, and eliminate of hot spots. In particular, specific processes have been developed to eliminate these hot spots which are most costly in terms of occupational exposure due to the need for reactor maintenance. This paper sets out the general approach adopted at EDF so far to cope with the problem of hot spots, illustrated by experience at Blayais 3 and 4.« less
Simulator test to study hot-flow problems related to a gas cooled reactor
NASA Technical Reports Server (NTRS)
Poole, J. W.; Freeman, M. P.; Doak, K. W.; Thorpe, M. L.
1973-01-01
An advance study of materials, fuel injection, and hot flow problems related to the gas core nuclear rocket is reported. The first task was to test a previously constructed induction heated plasma GCNR simulator above 300 kW. A number of tests are reported operating in the range of 300 kW at 10,000 cps. A second simulator was designed but not constructed for cold-hot visualization studies using louvered walls. A third task was a paper investigation of practical uranium feed systems, including a detailed discussion of related problems. The last assignment resulted in two designs for plasma nozzle test devices that could be operated at 200 atm on hydrogen.
Simulations of electron transport and ignition for direct-drive fast-ignition targets
NASA Astrophysics Data System (ADS)
Solodov, A. A.; Anderson, K. S.; Betti, R.; Gotcheva, V.; Myatt, J.; Delettrez, J. A.; Skupsky, S.; Theobald, W.; Stoeckl, C.
2008-11-01
The performance of high-gain, fast-ignition fusion targets is investigated using one-dimensional hydrodynamic simulations of implosion and two-dimensional (2D) hybrid fluid-particle simulations of hot-electron transport, ignition, and burn. The 2D/3D hybrid-particle-in-cell code LSP [D. R. Welch et al., Nucl. Instrum. Methods Phys. Res. A 464, 134 (2001)] and the 2D fluid code DRACO [P. B. Radha et al., Phys. Plasmas 12, 056307 (2005)] are integrated to simulate the hot-electron transport and heating for direct-drive fast-ignition targets. LSP simulates the transport of hot electrons from the place where they are generated to the dense fuel core where their energy is absorbed. DRACO includes the physics required to simulate compression, ignition, and burn of fast-ignition targets. The self-generated resistive magnetic field is found to collimate the hot-electron beam, increase the coupling efficiency of hot electrons with the target, and reduce the minimum energy required for ignition. Resistive filamentation of the hot-electron beam is also observed. The minimum energy required for ignition is found for hot electrons with realistic angular spread and Maxwellian energy-distribution function.
Estradiol alters body temperature regulation in the female mouse.
Krajewski-Hall, Sally J; Blackmore, Elise M; McMinn, Jessi R; Rance, Naomi E
2018-01-01
Hot flushes are due to estrogen withdrawal and characterized by the episodic activation of heat dissipation effectors. Recent studies (in humans and rats) have implicated neurokinin 3 (NK 3 ) receptor signaling in the genesis of hot flushes. Although transgenic mice are increasingly used for biomedical research, there is limited information on how 17β-estradiol and NK 3 receptor signaling alters thermoregulation in the mouse. In this study, a method was developed to measure tail skin temperature (T SKIN ) using a small data-logger attached to the surface of the tail, which, when combined with a telemetry probe for core temperature (T CORE ), allowed us to monitor thermoregulation in freely-moving mice over long durations. We report that estradiol treatment of ovariectomized mice reduced T CORE during the light phase (but not the dark phase) while having no effect on T SKIN or activity. Estradiol also lowered T CORE in mice exposed to ambient temperatures ranging from 20 to 36°C. Unlike previous studies in the rat, estradiol treatment of ovariectomized mice did not reduce T SKIN during the dark phase. Subcutaneous injections of an NK 3 receptor agonist (senktide) in ovariectomized mice caused an acute increase in T SKIN and a reduction in T CORE , consistent with the activation of heat dissipation effectors. These changes were reduced by estradiol, suggesting that estradiol lowers the sensitivity of central thermoregulatory pathways to NK 3 receptor activation. Overall, we show that estradiol treatment of ovariectomized mice decreases T CORE during the light phase, reduces the thermoregulatory effects of senktide and modulates thermoregulation differently than previously described in the rat.
NASA Astrophysics Data System (ADS)
Cai, Chao; Song, Bo; Wei, Qingsong; Yan, Wu; Xue, Pengju; Shi, Yusheng
2017-01-01
For the net-shape hot isostatic pressing (HIP) process, control of the internal surface roughness of as-HIPped parts remains a challenge for practical engineering. To reveal the evolution mechanism of the internal surface of the parts during the HIP process, the effect of different tooling materials (H13, T8, Cr12 steel, and graphite) as internal cores on the interfacial diffusion and surface roughness was systematically studied.
A Study of the Effects of Insulation Gaps on Building Heat Loss
1980-04-01
the Guarded Hot Box. Figure 4, taken from ASTM C-236, shows the essential details of the Guarded Hot Box Test Apparatus. Details of the Johns - Manville Research...The walls are 1-3/- inches thick and are of sandwich construction, with a core of 2 pcf polyvinyl-chloride foam ( Johns - Manville Vinylcel) with faces...Council of Canada (NRC) ane at the Johns - Manville Research Center, was installed and tested as a wall. The test history of that pane] is shown in Table 3
Imaging of High-Z doped, Imploded Capsule Cores
NASA Astrophysics Data System (ADS)
Prisbrey, Shon T.; Edwards, M. John; Suter, Larry J.
2006-10-01
The ability to correctly ascertain the shape of imploded fusion capsules is critical to be able to achieve the spherical symmetry needed to maximize the energy yield of proposed fusion experiments for the National Ignition Facility. Implosion of the capsule creates a hot, dense core. The introduction of a high-Z dopant into the gas-filled core of the capsule increases the amount of bremsstrahlung radiation produced in the core and should make the imaging of the imploded core easier. Images of the imploded core can then be analyzed to ascertain the symmetry of the implosion. We calculate that the addition of Ne gas into a deuterium gas core will increase the amount of radiation emission while preserving the surrogacy of the radiation and hydrodynamics in the indirect drive NIF hohlraum in the proposed cryogenic hohlraums. The increased emission will more easily enable measurement of asymmetries and tuning of the implosion.
Extending fullwave core ICRF simulation to SOL and antenna regions using FEM solver
NASA Astrophysics Data System (ADS)
Shiraiwa, S.; Wright, J. C.
2016-10-01
A full wave simulation approach to solve a driven RF waves problem including hot core, SOL plasmas and possibly antenna is presented. This approach allows for exploiting advantages of two different way of representing wave field, namely treating spatially dispersive hot conductivity in a spectral solver and handling complicated geometry in SOL/antenna region using an unstructured mesh. Here, we compute a mode set in each region with the RF electric field excitation on the connecting boundary between core and edge regions. A mode corresponding to antenna excitation is also computed. By requiring the continuity of tangential RF electric and magnetic fields, the solution is obtained as unique superposition of these modes. In this work, TORIC core spectral solver is modified to allow for mode excitation, and the edge region of diverted Alcator C-Mod plasma is modeled using COMSOL FEM package. The reconstructed RF field is similar in the core region to TORIC stand-alone simulation. However, it contains higher poloidal modes near the edge and captures a wave bounced and propagating in the poloidal direction near the vacuum-plasma boundary. These features could play an important role when the single power pass absorption is modest. This new capability will enable antenna coupling calculations with a realistic load plasma, including collisional damping in realistic SOL plasma and other loss mechanisms such as RF sheath rectification. USDoE Awards DE-FC02-99ER54512, DE-FC02-01ER54648.
Vynckier, A-K; De Beer, M; Monteyne, T; Voorspoels, J; De Beer, T; Remon, J P; Vervaet, C
2015-08-01
In this study hot-melt co-extrusion is used as processing technique to manufacture a fixed-dose combination product providing enteric protection to naproxen incorporated in the core and immediate release to esomeprazole magnesium embedded in the coat. The plasticizing effect of naproxen and triethyl citrate (TEC) was tested on the enteric polymers investigated (Eudragit(®) L100-55, HPMC-AS-LF and HPMCP-HP-50). Core matrix formulations containing HPMC-AS-LF, TEC and a naproxen load of 15, 30 and 50% were processed and characterized. The in vitro naproxen release in 0.1N HCl was prevented for 2h for all formulations. The physicochemical state of the drug in the extrudates was determined and a stability study was performed. Intermolecular interactions between naproxen and polymer were identified using attenuated total reflection Fourier-transform infrared (ATR FT-IR) spectroscopy. When esomeprazole magnesium was formulated in a polyethylene oxide 100K:polyethylene glycol 4K (1:1) matrix, separated from the naproxen-containing layer, the formulation could be easily processed and complete in vitro drug release was observed after 45 min. When co-extruding the core/coat dosage form it was observed that a third layer of polymer, separating the naproxen loaded enteric formulation in the core from the coat, is required to prevent degradation of the acid-labile esomeprazole magnesium at the core/coat interface. Copyright © 2015 Elsevier B.V. All rights reserved.
Acupuncture as treatment of hot flashes and the possible role of calcitonin gene-related Peptide.
Spetz Holm, Anna-Clara E; Frisk, Jessica; Hammar, Mats L
2012-01-01
The mechanisms behind hot flashes in menopausal women are not fully understood. The flashes in women are probably preceded by and actually initiated by a sudden downward shift in the set point for the core body temperature in the thermoregulatory center that is affected by sex steroids, β-endorphins, and other central neurotransmitters. Treatments that influence these factors may be expected to reduce hot flashes. Since therapy with sex steroids for hot flashes has appeared to cause a number of side effects and risks and women with hot flashes and breast cancer as well as men with prostate cancer and hot flashes are prevented from sex steroid therapy there is a great need for alternative therapies. Acupuncture affecting the opioid system has been suggested as an alternative treatment option for hot flashes in menopausal women and castrated men. The heat loss during hot flashes may be mediated by the potent vasodilator and sweat gland activator calcitonin gene-related peptide (CGRP) the concentration of which increases in plasma during flashes in menopausal women and, according to one study, in castrated men with flushes. There is also evidence for connections between the opioid system and the release of CGRP. In this paper we discuss acupuncture as a treatment alternative for hot flashes and the role of CGRP in this context.
Evaluation of physiological strain in hot work areas using thermal imagery.
Holm, Clint A; Pahler, Leon; Thiese, Matthew S; Handy, Rodney
2016-10-01
Monitoring core body temperature to identify heat strain in workers engaged in hot work in heat stress environments is intrusive and expensive. Nonintrusive, inexpensive methods are needed to calculate individual Physiological Strain Index (PSI). Thermal imaging and heart rate monitoring were used in this study to calculate Physiological Strain Index (PSI) from thermal imaging temperatures of human subjects wearing thermal protective garments during recovery from hot work. Ten male subjects were evaluated for physiological strain while participating in hot work. Thermal images of the head and neck were captured with a high-resolution thermal imaging camera concomitant with measures of gastrointestinal and skin temperature. Lin's concordance correlation coefficient (rho_c), Pearson's coefficient (r) and bias correction factor (C-b) were calculated to compare thermal imaging based temperatures to gastrointestinal temperatures. Calculations of PSI based thermal imaging recorded temperatures were compared to gastrointestinal based PSI. Participants reached a peak PSI of 5.2, indicating moderate heat strain. Sagittal measurements showed low correlation (rho_c=0.133), moderate precision (r=0.496) and low accuracy (C_b=0.269) with gastrointestinal temperature. Bland-Altman plots of imaging measurements showed increasing agreement as gastrointestinal temperature rose; however, the Limits of Agreement (LoA) fell outside the ±0.25C range of clinical significance. Bland-Altman plots of PSI calculated from imaging measurements showed increasing agreement as gastrointestinal temperature rose; however, the LoA fell outside the ±0.5 range of clinical significance. Results of this study confirmed previous research showing thermal imagery is not highly correlated to body core temperature during recovery from moderate heat strain in mild ambient conditions. Measurements display a trend toward increasing correlation at higher body core temperatures. Accuracy was not sufficient at mild to moderate heat strain to allow calculation of individual physiological stress. Copyright © 2016 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hasegawa, Yasuhiro; Pudritz, Ralph E., E-mail: yasu@asiaa.sinica.edu.tw, E-mail: pudritz@physics.mcmaster.ca
2013-11-20
The rapid growth of observed exoplanets has revealed the existence of several distinct planetary populations in the mass-period diagram. Two of the most surprising are (1) the concentration of gas giants around 1 AU and (2) the accumulation of a large number of low-mass planets with tight orbits, also known as super-Earths and hot Neptunes. We have recently shown that protoplanetary disks have multiple planet traps that are characterized by orbital radii in the disks and halt rapid type I planetary migration. By coupling planet traps with the standard core accretion scenario, we showed that one can account for themore » positions of planets in the mass-period diagram. In this paper, we demonstrate quantitatively that most gas giants formed at planet traps tend to end up around 1 AU, with most of these being contributed by dead zones and ice lines. We also show that a large fraction of super-Earths and hot Neptunes are formed as 'failed' cores of gas giants—this population being constituted by comparable contributions from dead zone and heat transition traps. Our results are based on the evolution of forming planets in an ensemble of disks where we vary only the lifetimes of disks and their mass accretion rates onto the host star. We show that a statistical treatment of the evolution of a large population of planetary cores caught in planet traps accounts for the existence of three distinct exoplanetary populations—the hot Jupiters, the more massive planets around r = 1 AU, and the short-period super-Earths and hot Neptunes. There are very few populations that feed into the large orbital radii characteristic of the imaged Jovian planet, which agrees with recent surveys. Finally, we find that low-mass planets in tight orbits become the dominant planetary population for low-mass stars (M {sub *} ≤ 0.7 M {sub ☉}).« less
Investigation of Abnormal Heat Transfer and Flow in a VHTR Reactor Core
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kawaji, Masahiro; Valentin, Francisco I.; Artoun, Narbeh
2015-12-21
The main objective of this project was to identify and characterize the conditions under which abnormal heat transfer phenomena would occur in a Very High Temperature Reactor (VHTR) with a prismatic core. High pressure/high temperature experiments have been conducted to obtain data that could be used for validation of VHTR design and safety analysis codes. The focus of these experiments was on the generation of benchmark data for design and off-design heat transfer for forced, mixed and natural circulation in a VHTR core. In particular, a flow laminarization phenomenon was intensely investigated since it could give rise to hot spotsmore » in the VHTR core.« less
Krull, Ashley A; Larsen, Sarah A; Clifton, Donald K; Neal-Perry, Genevieve; Steiner, Robert A
2017-10-01
Vasomotor symptoms (VMS; or hot flashes) plague millions of reproductive-aged men and women who have natural or iatrogenic loss of sex steroid production. Many affected individuals are left without treatment options because of contraindications to hormone replacement therapy and the lack of equally effective nonhormonal alternatives. Moreover, development of safer, more effective therapies has been stymied by the lack of an animal model that recapitulates the hot-flash phenomenon and enables direct testing of hypotheses regarding the pathophysiology underlying hot flashes. To address these problems, we developed a murine model for hot flashes and a comprehensive method for measuring autonomic and behavioral thermoregulation in mice. We designed and constructed an instrument called a thermocline that produces a thermal gradient along which mice behaviorally adapt to a thermal challenge to their core body temperature set point while their thermal preference over time is tracked and recorded. We tested and validated this murine model for VMS by administration of a TRPV1 agonist and a neurokinin B receptor agonist, capsaicin and senktide, respectively, to unrestrained mice and observed their autonomic and behavioral responses. Following both treatments, the mice exhibited a VMS-like response characterized by a drop in core body temperature and cold-seeking behavior on the thermocline. Senktide also caused a rise in tail skin temperature and increased Fos expression in the median preoptic area, a hypothalamic temperature control center. This dynamic model may be used to fully explore the cellular and molecular bases for VMS and to develop and test new therapeutic options. Copyright © 2017 Endocrine Society.
The effect of prolonged light intensity exercise in the heat on executive function.
Parker, Sarah M; Erin, Jennifer R; Pryor, Riana R; Khorana, Priya; Suyama, Joe; Guyette, Frank X; Reis, Steven E; Hostler, David
2013-09-01
When people are involved in outdoor activities, it is important to be able to assess a situation and make rational decisions. The goal of this study is to determine the effects of 90 minutes of light-intensity exercise in a hot environment on executive functioning capabilities of healthy individuals. In this prospective laboratory study, 40 healthy male and female subjects 18 to 45 years of age performed treadmill exercise while wearing athletic clothing and a backpack in either a hot or temperate environment. Vital signs, core and skin temperature, and perceptual measures (thermal sensation, sweating, comfort, and perceived exertion) were measured before, during, and after the treadmill test. Cognitive function was measured before and after the treadmill test using the Wisconsin Card Sorting Test (WCST) and a Psychomotor Vigilance Test (PVT). Subjects in the hot condition reached a similar core temp of 38.2° ± 0.5°C vs 37.7° ± 0.3°C (P = .325) in the temperate group but had a higher heart rate (P < .001) and skin temperature (P < .001). Hot and normal temperature groups did not differ in their PVT performance. There were more correct responses (P < .001), fewer errors (P < .001), and more conceptual responses (P = .001) on the WCST after exertion in both the hot room and normal temperature room conditions. Perseverations and perseverative errors (P = .002) decreased in both groups after exertion. Conditions of mild heat stress coupled with modest rehydration and short hiking treks do not appear to negatively affect executive function or vigilance. Copyright © 2013 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.
A selective estrogen receptor modulator for the treatment of hot flushes.
Wallace, Owen B; Lauwers, Kenneth S; Dodge, Jeffrey A; May, Scott A; Calvin, Joel R; Hinklin, Ronald; Bryant, Henry U; Shetler, Pamela K; Adrian, Mary D; Geiser, Andrew G; Sato, Masahiko; Burris, Thomas P
2006-02-09
A selective estrogen receptor modulator (SERM) for the potential treatment of hot flushes is described. (R)-(+)-7,9-difluoro-5-[4-(2-piperidin-1-ylethoxy)phenyl]-5H-6-oxachrysen-2-ol, LSN2120310, potently binds ERalpha and ERbeta and is an antagonist in MCF-7 breast adenocarcinoma and Ishikawa uterine cancer cell lines. The compound is a potent estrogen antagonist in the rat uterus. In ovariectomized rats, the compound lowers cholesterol, maintains bone mineral density, and is efficacious in a morphine dependent rat model of hot flush efficacy.
NASA Astrophysics Data System (ADS)
Klahr, Hubert; Brandner, Wolfgang
2011-02-01
1. Historical notes on planet formation Bodenheimer; 2. The formation and evolution of planetary systems Bouwman et al.; 3. Destruction of protoplanetary disks by photoevaporation Richling, Hollenbach and Yorke; 4. Turbulence in protoplanetary accretion disks Klahr, Rozyczka, Dziourkevitch, Wunsch and Johansen; 5. The origin of solids in the early solar system Trieloff and Palme; 6. Experiments on planetesimal formation Wurm and Blum; 7. Dust coagulation in protoplanetary disks Henning, Dullemond, Wolf and Dominik; 8. The accretion of giant planet cores Thommes and Duncan; 9. Planetary transits: direct vision of extrasolar planets Lecavelier des Etangs and Vidal-Madjar; 10. The core accretion - gas capture model Hubickyj; 11. Properties of exoplanets Marcy, Fischer, Butler and Vogt; 12. Giant planet formation: theories meet observations Boss; 13. From hot Jupiters to hot Neptures … and below Lovis, Mayor and Udry; 14. Disk-planet interaction and migration Masset and Kley; 15. The Brown Dwarf - planet relation Bate; 16. From astronomy to astrobiology Brandner; 17. Overview and prospective Lin.
Natural Circulation Level Optimization and the Effect during ULOF Accident in the SPINNOR Reactors
NASA Astrophysics Data System (ADS)
Abdullah, Ade Gafar; Su'ud, Zaki; Kurniadi, Rizal; Kurniasih, Neny; Yulianti, Yanti
2010-12-01
Natural circulation level optimization and the effect during loss of flow accident in the 250 MWt MOX fuelled small Pb-Bi Cooled non-refueling nuclear reactors (SPINNOR) have been performed. The simulation was performed using FI-ITB safety code which has been developed in ITB. The simulation begins with steady state calculation of neutron flux, power distribution and temperature distribution across the core, hot pool and cool pool, and also steam generator. When the accident is started due to the loss of pumping power the power distribution and the temperature distribution of core, hot pool and cool pool, and steam generator change. Then the feedback reactivity calculation is conducted, followed by kinetic calculation. The process is repeated until the optimum power distribution is achieved. The results show that the SPINNOR reactor has inherent safety capability against this accident.
Unveiling Deeply Embedded Sources by Near-Infrared Polarimetric Imaging
NASA Astrophysics Data System (ADS)
Yao, Yongqiang; Ishii, Miki; Nagata, Tetsuya; Nakaya, Hidehiko; Sato, Shuji
2000-10-01
Near-infrared polarimetric images are presented for six molecular outflow sources: IRAS 20050+2720, IRAS 20126+4104, IRAS 20188+3928, S233, AFGL 5180, and AFGL 6366S. All the regions are found to exhibit reflection nebulae and to be associated with massive and clustered star formation. By inspecting polarimetric patterns in the nebulae, we have identified six deeply embedded sources (DESs) which illuminate circumstellar nebulosity but are not detectable in wavelengths shorter than 2 μm. While the DES in IRAS 20050 coincides with an infrared source in a previous, longer wavelength observation and the one in IRAS 20126 with a hot molecular core, the nature of the other newly discovered DESs is not known. From the compilation of the observations of DESs over a large wavelength range, we suspect that the DESs possess characteristics similar to hot molecular cores and are likely to be in the pre-ultracompact H II region phase of massive star formation.
NASA Astrophysics Data System (ADS)
Schmid-Burgk, J.; Densing, R.; Krugel, E.; Nett, H.; Roser, H. P.; Schafer, F.; Schwaab, G.; van der Wal, P.; Wattenbach, R.
1989-05-01
Observations of a 6 x 8-arcmin region at the core of Orion molecular cloud 1 are reported. Data obtained in the 806-GHz line of CO using the NASA Kuiper Airborne Observatory on September 15 and 17, 1986 are presented graphically and analyzed in detail. The results indicate a region of density 10,000/cu cm or greater and temperature of about 50 K extending several arcmin from the core; the total luminosities due to CO (J = 7-6) and to dust are estimated as 10 and 100,000 solar luminosities, respectively. Particular attention is given to the dust-embedded IR cluster BN-KL (with high-velocity outflow suggesting small optical depths) and a second more prominent feature about 2 arcmin to the south (with outflow of about 1 solar mass of material at 500-1000 K, radiating about 0.25 solar luminosity in CO 7-6).
Smalyuk, V A; Tipton, R E; Pino, J E; Casey, D T; Grim, G P; Remington, B A; Rowley, D P; Weber, S V; Barrios, M; Benedetti, L R; Bleuel, D L; Bradley, D K; Caggiano, J A; Callahan, D A; Cerjan, C J; Clark, D S; Edgell, D H; Edwards, M J; Frenje, J A; Gatu-Johnson, M; Glebov, V Y; Glenn, S; Haan, S W; Hamza, A; Hatarik, R; Hsing, W W; Izumi, N; Khan, S; Kilkenny, J D; Kline, J; Knauer, J; Landen, O L; Ma, T; McNaney, J M; Mintz, M; Moore, A; Nikroo, A; Pak, A; Parham, T; Petrasso, R; Sayre, D B; Schneider, M B; Tommasini, R; Town, R P; Widmann, K; Wilson, D C; Yeamans, C B
2014-01-17
We present the first results from an experimental campaign to measure the atomic ablator-gas mix in the deceleration phase of gas-filled capsule implosions on the National Ignition Facility. Plastic capsules containing CD layers were filled with tritium gas; as the reactants are initially separated, DT fusion yield provides a direct measure of the atomic mix of ablator into the hot spot gas. Capsules were imploded with x rays generated in hohlraums with peak radiation temperatures of ∼294 eV. While the TT fusion reaction probes conditions in the central part (core) of the implosion hot spot, the DT reaction probes a mixed region on the outer part of the hot spot near the ablator-hot-spot interface. Experimental data were used to develop and validate the atomic-mix model used in two-dimensional simulations.
Analysis of Material Sample Heated by Impinging Hot Hydrogen Jet in a Non-Nuclear Tester
NASA Technical Reports Server (NTRS)
Wang, Ten-See; Foote, John; Litchford, Ron
2006-01-01
A computational conjugate heat transfer methodology was developed and anchored with data obtained from a hot-hydrogen jet heated, non-nuclear materials tester, as a first step towards developing an efficient and accurate multiphysics, thermo-fluid computational methodology to predict environments for hypothetical solid-core, nuclear thermal engine thrust chamber. The computational methodology is based on a multidimensional, finite-volume, turbulent, chemically reacting, thermally radiating, unstructured-grid, and pressure-based formulation. The multiphysics invoked in this study include hydrogen dissociation kinetics and thermodynamics, turbulent flow, convective and thermal radiative, and conjugate heat transfers. Predicted hot hydrogen jet and material surface temperatures were compared with those of measurement. Predicted solid temperatures were compared with those obtained with a standard heat transfer code. The interrogation of physics revealed that reactions of hydrogen dissociation and recombination are highly correlated with local temperature and are necessary for accurate prediction of the hot-hydrogen jet temperature.
Accretion of Rocky Planets by Hot Jupiters
NASA Astrophysics Data System (ADS)
Ketchum, Jacob A.; Adams, Fred C.; Bloch, Anthony M.
2011-11-01
The observed population of Hot Jupiters displays a stunning variety of physical properties, including a wide range of densities and core sizes for a given planetary mass. Motivated by the observational sample, this Letter studies the accretion of rocky planets by Hot Jupiters, after the Jovian planets have finished their principal migration epoch and become parked in ~4 day orbits. In this scenario, rocky planets form later and then migrate inward due to torques from the remaining circumstellar disk, which also damps the orbital eccentricity. This mechanism thus represents one possible channel for increasing the core masses and metallicities of Hot Jupiters. This Letter determines probabilities for the possible end states for the rocky planet: collisions with the Jovian planets, accretion onto the star, ejection from the system, and long-term survival of both planets. These probabilities depend on the mass of the Jovian planet and its starting orbital eccentricity, as well as the eccentricity damping rate for the rocky planet. Since these systems are highly chaotic, a large ensemble (N ~ 103) of simulations with effectively equivalent starting conditions is required. Planetary collisions are common when the eccentricity damping rate is sufficiently low, but are rare otherwise. For systems that experience planetary collisions, this work determines the distributions of impact velocities—both speeds and impact parameters—for the collisions. These velocity distributions help determine the consequences of the impacts, e.g., where energy and heavy elements are deposited within the giant planets.
Content-based analysis of Ki-67 stained meningioma specimens for automatic hot-spot selection.
Swiderska-Chadaj, Zaneta; Markiewicz, Tomasz; Grala, Bartlomiej; Lorent, Malgorzata
2016-10-07
Hot-spot based examination of immunohistochemically stained histological specimens is one of the most important procedures in pathomorphological practice. The development of image acquisition equipment and computational units allows for the automation of this process. Moreover, a lot of possible technical problems occur in everyday histological material, which increases the complexity of the problem. Thus, a full context-based analysis of histological specimens is also needed in the quantification of immunohistochemically stained specimens. One of the most important reactions is the Ki-67 proliferation marker in meningiomas, the most frequent intracranial tumour. The aim of our study is to propose a context-based analysis of Ki-67 stained specimens of meningiomas for automatic selection of hot-spots. The proposed solution is based on textural analysis, mathematical morphology, feature ranking and classification, as well as on the proposed hot-spot gradual extinction algorithm to allow for the proper detection of a set of hot-spot fields. The designed whole slide image processing scheme eliminates such artifacts as hemorrhages, folds or stained vessels from the region of interest. To validate automatic results, a set of 104 meningioma specimens were selected and twenty hot-spots inside them were identified independently by two experts. The Spearman rho correlation coefficient was used to compare the results which were also analyzed with the help of a Bland-Altman plot. The results show that most of the cases (84) were automatically examined properly with two fields of view with a technical problem at the very most. Next, 13 had three such fields, and only seven specimens did not meet the requirement for the automatic examination. Generally, the Automatic System identifies hot-spot areas, especially their maximum points, better. Analysis of the results confirms the very high concordance between an automatic Ki-67 examination and the expert's results, with a Spearman rho higher than 0.95. The proposed hot-spot selection algorithm with an extended context-based analysis of whole slide images and hot-spot gradual extinction algorithm provides an efficient tool for simulation of a manual examination. The presented results have confirmed that the automatic examination of Ki-67 in meningiomas could be introduced in the near future.
Fiber-optic anemometer based on single-walled carbon nanotube coated tilted fiber Bragg grating.
Zhang, Yang; Wang, Fang; Liu, Zigeng; Duan, Zhihui; Cui, Wenli; Han, Jie; Gu, Yiying; Wu, Zhenlin; Jing, Zhenguo; Sun, Changsen; Peng, Wei
2017-10-02
In this work, a novel and simple optical fiber hot-wire anemometer based on single-walled carbon nanotubes (SWCNTs) coated tilted fiber Bragg grating (TFBG) is proposed and demonstrated. For the hot-wire wind speed sensor design, TFBG is an ideal in-fiber sensing structure due to its unique features. It is utilized as both light coupling and temperature sensing element without using any geometry-modified or uncommon fiber, which simplifies the sensor structure. To further enhance the thermal conversion capability, SWCNTs are coated on the surface of the TFBG instead of traditional metallic materials, which have excellent thermal characteristics. When a laser light is pumped into the sensor, the pump light propagating in the core will be easily coupled into cladding of the fiber via the TFBG and strongly absorbed by the SWCNTs thin film. This absorption acts like a hot-wire raising the local temperature of the fiber, which is accurately detected by the TFBG resonance shift. In the experiments, the sensor's performances were investigated and controlled by adjusting the inherent angle of the TFBG, the thickness of SWCNTs film, and the input power of the pump laser. It was demonstrated that the developed anemometer exhibited significant light absorption efficiency up to 93%, and the maximum temperature of the local area on the fiber was heated up to 146.1°C under the relatively low pump power of 97.76 mW. The sensitivity of -0.3667 nm/(m/s) at wind speed of 1.0 m/s was measured with the selected 12° TFBG and 1.6 μm film.
NuSTAR Observations of WISE J1036+0449, a Galaxy at z~1 Obscured by Hot Dust
NASA Astrophysics Data System (ADS)
Ricci, C.; Assef, R. J.; Stern, D.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A. W.; Boggs, S.; Boorman, P. G.; Brandt, W. N.; Brightman, M.; Chang, C. S.; Chen, C.-T. J.; Christensen, F. E.; Comastri, A.; Craig, W. W.; Díaz-Santos, T.; Eisenhardt, P. R.; Farrah, D.; Gandhi, P.; Hailey, C. J.; Harrison, F. A.; Jun, H. D.; Koss, M. J.; LaMassa, S.; Lansbury, G. B.; Markwardt, C. B.; Stalevski, M.; Stanley, F.; Treister, E.; Tsai, C.-W.; Walton, D. J.; Wu, J. W.; Zappacosta, L.; Zhang, W. W.
2017-01-01
Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer’s all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z> 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z˜ 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 ({L}{Bol}≃ 8× {10}46 {erg} {{{s}}}-1). We find evidence of a broadened component in Mg II, which would imply a black hole mass of {M}{BH}≃ 2× {10}8 {M}⊙ and an Eddington ratio of {λ }{Edd}≃ 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of {N}{{H}}≃ (2{--}15)× {10}23 {{cm}}-2. The source has an intrinsic 2-10 keV luminosity of ˜ 6× {10}44 {erg} {{{s}}}-1, a value significantly lower than that expected from the mid-infrared/X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z≲ 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.
NuSTAR Observations of WISE J1036+0449, A Galaxy at Z Approx. 1 Obscured by Hot Dust
NASA Technical Reports Server (NTRS)
Ricci, C.; Assef, R. J.; Stern, D.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A. W.; Boggs, S.;
2017-01-01
Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer's all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z > 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z approx. 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (L(BOL) approx. = 8 x 10(exp 46) erg/s). We find evidence of a broadened component in Mg II, which would imply a black hole mass of M(BH) approx. = 2 x 10(exp 8) Stellar Mass and an Eddington ratio of lambda(Edd) approx. = 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of N(H) approx. = (2-15) x 10(exp 23)/sq cm. The source has an intrinsic 2-10 keV luminosity of approx. 6 x 10(exp 44) erg/s, a value significantly lower than that expected from the mid-infrared X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z < or approx. 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.
NuSTAR Observations of WISE J1036+0449, A Galaxy at zeta approx 1 Obscured by Hot Dust
NASA Technical Reports Server (NTRS)
Ricci, C.; Assef, R. J.; Stern, Daniel K.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A.W.; Zhang, William W.;
2017-01-01
Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer's all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z > 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z approx. 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (L(sub BOL) approx. = 8 x 10(exp 46) erg/s). We find evidence of a broadened component in Mg II, which would imply a black hole mass of M(BH) approx. = 2 x 10(exp 8) Stellar Mass and an Eddington ratio of lambda(sub Edd) approx. = 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of N(sub H) approx. = (2-15) x 10(exp 23)/sq cm. The source has an intrinsic 2-10 keV luminosity of approx. 6 x 10(exp 44) erg/s, a value significantly lower than that expected from the mid-infrared X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z < or approx. 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.
Conceptual Design and Feasibility of Foil Bearings for Rotorcraft Engines: Hot Core Bearings
NASA Technical Reports Server (NTRS)
Howard, Samuel A.
2007-01-01
Recent developments in gas foil bearing technology have led to numerous advanced high-speed rotating system concepts, many of which have become either commercial products or experimental test articles. Examples include oil-free microturbines, motors, generators and turbochargers. The driving forces for integrating gas foil bearings into these high-speed systems are the benefits promised by removing the oil lubrication system. Elimination of the oil system leads to reduced emissions, increased reliability, and decreased maintenance costs. Another benefit is reduced power plant weight. For rotorcraft applications, this would be a major advantage, as every pound removed from the propulsion system results in a payload benefit.. Implementing foil gas bearings throughout a rotorcraft gas turbine engine is an important long-term goal that requires overcoming numerous technological hurdles. Adequate thrust bearing load capacity and potentially large gearbox applied radial loads are among them. However, by replacing the turbine end, or hot section, rolling element bearing with a gas foil bearing many of the above benefits can be realized. To this end, engine manufacturers are beginning to explore the possibilities of hot section gas foil bearings in propulsion engines. This overview presents a logical follow-on activity by analyzing a conceptual rotorcraft engine to determine the feasibility of a foil bearing supported core. Using a combination of rotordynamic analyses and a load capacity model, it is shown to be reasonable to consider a gas foil bearing core section. In addition, system level foil bearing testing capabilities at NASA Glenn Research Center are presented along with analysis work being conducted under NRA Cooperative Agreements.
OT1_ebergin_5: A Systematic Survery of the Water D to H Ratio in Hot Molecular Cores
NASA Astrophysics Data System (ADS)
Bergin, E.
2010-07-01
The D/H ratio of water and the enrichment of HDO relative to H2O in comets, oceans, and interstellar water vapor, has been posited as one of the primary links between chemistry in the cold (T = 10-20 K) dense interstellar medium (ISM) and chemistry in the Solar Nebula. However, there are only ~10 measurements of HDO/H2O, even in hot (T > 100 K) molecular cores, which have the most favorable chemistry (due to fossil evaporation of D-enriched ices) and excitation. In addition the existing measurements have a wide range of uncertainty, making it impossible to discern the presence of source-to-source variations, which could hint at the origin of deuterium enrichments in the dense ISM. We propose here to change this statistic with a systematic survey of HDO and H2O in a sample of 20 hot molecular cores spanning a two order of magnitude range in mass and luminosity. This will increase the number of known water D/H ratios by ~200%. This program is unique in scope for Herschel and requires the uniformity in calibration and high spectral resolution offered by the HIFI instrument. With the stability of HIFI we will be able to derive D/H ratios with significantly less uncertainty. Our observations will be combined with theoretical chemical models to explore the statistics offered by this sample. By looking at a large number of objects with a range of conditions we aim to unlock the secrets of water deuteration in the interstellar space.
Kim, Tae Hoon; Kim, Eun-Hye; Cho, Hwi-young
2015-07-01
To investigate the effects of the CORE programme on pain at rest, movement-induced pain, secondary pain, active range of motion, and proprioception deficits in female office workers with chronic low back pain. Randomized controlled trial. Rehabilitation clinics. A total of 53 participants with chronic low back pain were randomized into the CORE group and the control group. CORE group participants underwent the 30-minute CORE programme, five times per week, for eight weeks, with additional use of hot-packs and transcutaneous electrical nerve stimulation, while the control group used only hot-packs and transcutaneous electrical nerve stimulation. Participants were evaluated pretest, posttest, and two months after the intervention period to measure resting and movement-induced pain, pressure pain as secondary pain, active range of pain-free motion, and trunk proprioception. Pain intensity at rest (35.6 ±5.9 mm) and during movement (39.4 ±9.1 mm) was significantly decreased in the CORE group following intervention compared with the control group. There were significant improvements in pressure pain thresholds (quadratus lumborum: 2.2 ±0.7 kg/cm(2); sacroiliac joint: 2.0 ±0.7 kg/cm(2)), active range of motion (flexion: 30.8 ±14.3°; extension: 6.6 ±2.5°), and proprioception (20° flexion: 4.3 ±2.4°; 10° extension: 3.1 ±2.0°) in the CORE group following intervention (all p < 0.05). These improvements were maintained at the two-month follow-up. The control group did not show significant improvements in any measured parameter. The CORE programme is an effective intervention for reducing pain at rest and movement-induced pain, and for improving the active range of motion and trunk proprioception in female office workers with chronic low back pain. © The Author(s) 2014.
48 CFR 925.7000 - Scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7000 Scope of subpart. This subpart prescribes policies for selection for contract award of nuclear hot cell services when one of the competitors is a foreign company. This subpart does not apply to the acquisition and use of nuclear hot cell...
48 CFR 925.7000 - Scope of subpart.
Code of Federal Regulations, 2012 CFR
2012-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7000 Scope of subpart. This subpart prescribes policies for selection for contract award of nuclear hot cell services when one of the competitors is a foreign company. This subpart does not apply to the acquisition and use of nuclear hot cell...
48 CFR 925.7000 - Scope of subpart.
Code of Federal Regulations, 2013 CFR
2013-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7000 Scope of subpart. This subpart prescribes policies for selection for contract award of nuclear hot cell services when one of the competitors is a foreign company. This subpart does not apply to the acquisition and use of nuclear hot cell...
48 CFR 925.7000 - Scope of subpart.
Code of Federal Regulations, 2014 CFR
2014-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7000 Scope of subpart. This subpart prescribes policies for selection for contract award of nuclear hot cell services when one of the competitors is a foreign company. This subpart does not apply to the acquisition and use of nuclear hot cell...
48 CFR 925.7000 - Scope of subpart.
Code of Federal Regulations, 2011 CFR
2011-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7000 Scope of subpart. This subpart prescribes policies for selection for contract award of nuclear hot cell services when one of the competitors is a foreign company. This subpart does not apply to the acquisition and use of nuclear hot cell...
Nuclear reactor removable radial shielding assembly having a self-bowing feature
Pennell, William E.; Kalinowski, Joseph E.; Waldby, Robert N.; Rylatt, John A.; Swenson, Daniel V.
1978-01-01
A removable radial shielding assembly for use in the periphery of the core of a liquid-metal-cooled fast-breeder reactor, for closing interassembly gaps in the reactor core assembly load plane prior to reactor criticality and power operation to prevent positive reactivity insertion. The assembly has a lower nozzle portion for inserting into the core support and a flexible heat-sensitive bimetallic central spine surrounded by blocks of shielding material. At refueling temperature and below the spine is relaxed and in a vertical position so that the tolerances permitted by the interassembly gaps allow removal and replacement of the various reactor core assemblies. During an increase in reactor temperature from refueling to hot standby, the bimetallic spine expands, bowing the assembly toward the core center line, exerting a radially inward gap-closing-force on the above core load plane of the reactor core assembly, closing load plane interassembly gaps throughout the core prior to startup and preventing positive reactivity insertion.
Scheduler for multiprocessor system switch with selective pairing
Gara, Alan; Gschwind, Michael Karl; Salapura, Valentina
2015-01-06
System, method and computer program product for scheduling threads in a multiprocessing system with selective pairing of processor cores for increased processing reliability. A selective pairing facility is provided that selectively connects, i.e., pairs, multiple microprocessor or processor cores to provide one highly reliable thread (or thread group). The method configures the selective pairing facility to use checking provide one highly reliable thread for high-reliability and allocate threads to corresponding processor cores indicating need for hardware checking. The method configures the selective pairing facility to provide multiple independent cores and allocate threads to corresponding processor cores indicating inherent resilience.
Self-defrosting recuperative air-to-air heat exchanger
Drake, Richard L.
1993-01-01
A heat exchanger includes a stationary spirally or concentrically wound heat exchanger core with rotating baffles on upper and lower ends thereof. The rotating baffles include rotating inlets and outlets which are in communication with respective fixed inlets and outlets via annuli. The rotation of the baffles causes a concurrent rotation of the temperature distribution within the stationary exchanger core, thereby preventing frost build-up in some applications and preventing the formation of hot spots in other applications.
Massive Infrared-Quiet Dense Cores: Unveiling the Initial Conditions of High-Mass Star Formation
NASA Astrophysics Data System (ADS)
Motte, F.; Bontemps, S.; Schneider, N.; Schilke, P.; Menten, K. M.
2008-05-01
As Th. Henning said at the conference, cold precursors of high-mass stars are now ``hot topics''. We here propose some observational criteria to identify massive infrared-quiet dense cores which can host the high-mass analogs of Class~0 protostars and pre-stellar condensations. We also show how far-infrared to millimeter imaging surveys of entire complexes forming OB stars are starting to unveil the initial conditions of high-mass star formation.
Studies of a plasma with a hot dense core in LAPD
NASA Astrophysics Data System (ADS)
van Compernolle, Bart; Gekelman, Walter; Pribyl, Patrick; Cooper, Chris
2009-11-01
Recently, considerable effort in the LArge Plasma Device at UCLA (LAPD) has gone into the study of large cathodes which would enable higher discharge currents and higher densities. The new cathode is made out of Lanthanum HexaBoride (LaB6). LaB6 has a low work function and has higher emissivity than Barium oxide coated cathodes. The operating temperature of LaB6 cathodes lies above 1600 degrees Celsius. Tests of this cathode in the Enormous Toroidal Plasma Device (ETPD) showed that densities in excess of 2 10^13 cm-3 and electron temperatures of 12 eV are feasible. Small LaB6 cathodes (3mm - 2cm) have been used before in LAPD in several experiments on heat transport and on magnetized flux ropes. The cathode presented in this paper has a 8 cm diameter, and can be positioned at different radial locations. The cathode will be pulsed into the standard background plasma (ne= 2 10^12 cm-3, .25 <=Te<=6 eV, dia = 60 cm, L = 18 m) creating a plasma with a hot dense core. We present the characterization of the core plasma at different conditions. Studies of the heat transport and density spreading at the interface between the core plasma and background plasma will be done by use of a variety of probes (Langmuir, magnetic, Mach, emissive) as well as fast photography.
Improving hot region prediction by parameter optimization of density clustering in PPI.
Hu, Jing; Zhang, Xiaolong
2016-11-01
This paper proposed an optimized algorithm which combines density clustering of parameter selection with feature-based classification for hot region prediction. First, all the residues are classified by SVM to remove non-hot spot residues, then density clustering of parameter selection is used to find hot regions. In the density clustering, this paper studies how to select input parameters. There are two parameters radius and density in density-based incremental clustering. We firstly fix density and enumerate radius to find a pair of parameters which leads to maximum number of clusters, and then we fix radius and enumerate density to find another pair of parameters which leads to maximum number of clusters. Experiment results show that the proposed method using both two pairs of parameters provides better prediction performance than the other method, and compare these two predictive results, the result by fixing radius and enumerating density have slightly higher prediction accuracy than that by fixing density and enumerating radius. Copyright © 2016. Published by Elsevier Inc.
NASA Astrophysics Data System (ADS)
Dirpan, Andi
2018-05-01
This research was intended to select the best handling methods or postharvest technologies that can be used to maintain the quality of citrus fruit in Selayar, South Sulawesi, Indonesia among (1) modified atmosphere packaging (MAP (2) Controlled atmosphere storage (CAS) (3) coatings (4) hot water treatment (5) Hot Calcium Dip (HCD) by using combination between an analytic hierarchy process (AHP) and TOPSIS. Improving quality, applicability, increasing shelf life and reducing cost are used as the criteria to determine the best postharvest technologies. The results show that the most important criteria for selecting postharvest technology is improving quality followed by increasing shelf life, reducing cost and applicability. Furthermore, by using TOPSIS, it is clear that the postharvest technology that had the lowest rangking is modified atmosphere packaging (MAP), followed by controlled atmosphere storage (CAS), coatings, hot calcium dip (HCD) and hot water treatment (HWT). Therefore, it can be concluded that the best postharvest technology method for Selayar citrus is modified atmosphere packaging (MAP).
Swiderska, Zaneta; Markiewicz, Tomasz; Grala, Bartlomiej; Slodkowska, Janina
2015-01-01
The paper presents a combined method for an automatic hot-spot areas selection based on penalty factor in the whole slide images to support the pathomorphological diagnostic procedure. The studied slides represent the meningiomas and oligodendrogliomas tumor on the basis of the Ki-67/MIB-1 immunohistochemical reaction. It allows determining the tumor proliferation index as well as gives an indication to the medical treatment and prognosis. The combined method based on mathematical morphology, thresholding, texture analysis and classification is proposed and verified. The presented algorithm includes building a specimen map, elimination of hemorrhages from them, two methods for detection of hot-spot fields with respect to an introduced penalty factor. Furthermore, we propose localization concordance measure to evaluation localization of hot spot selection by the algorithms in respect to the expert's results. Thus, the results of the influence of the penalty factor are presented and discussed. It was found that the best results are obtained for 0.2 value of them. They confirm effectiveness of applied approach.
Effect of antiperspirants on whole body sweat rate and thermoregulation.
Burry, J S; Evans, R L; Rawlings, A V; Shiu, J
2003-08-01
It is well established that the evaporation of sweat from the human body surface is the main mechanism by which heat balance is maintained following a rise in body core temperature. Since the introduction of the first brand name antiperspirant in the United States during the early 1900s, antiperspirant products designed to control underarm wetness have grown to represent one of the largest cosmetic categories in most global markets. However, although axillary sweating only constitutes less than 1% of whole body sweat rate, consumers, particularly in hot countries, have begun to articulate the concern that antiperspirants may interfere with the body's natural cooling process. To investigate this, we undertook carefully designed experiments that measured the effects of axillary antiperspirant application on whole body sweat rate and body core temperature, following a regimen of exercise-induced heat stress in a hot environment in human volunteers. Our data show clearly that although antiperspirant prevents sweat production in the axillary area, this does not impact the ability of the body to thermoregulate following a rise in body core temperature. Thus, recent consumer questioning over this aspect of antiperspirant use appears to be unwarranted.
Influence of smooth temperature variation on hotspot ignition
NASA Astrophysics Data System (ADS)
Reinbacher, Fynn; Regele, Jonathan David
2018-01-01
Autoignition in thermally stratified reactive mixtures originates in localised hotspots. The ignition behaviour is often characterised using linear temperature gradients and more recently constant temperature plateaus combined with temperature gradients. Acoustic timescale characterisation of plateau regions has been successfully used to characterise the type of mechanical disturbance that will be created from a plateau core ignition. This work combines linear temperature gradients with superelliptic cores in order to more accurately account for a local temperature maximum of finite size and the smooth temperature variation contained inside realistic hotspot centres. A one-step Arrhenius reaction is used to model a H2-air reactive mixture. Using the superelliptic approach a range of behaviours for temperature distributions are investigated by varying the temperature profile between the gradient only and plateau and gradient bounding cases. Each superelliptic case is compared to a respective plateau and gradient case where simple acoustic timescale characterisation may be performed. It is shown that hot spots equivalent with excitation-to-acoustic timescale ratios sufficiently greater than unity exhibit behaviour very similar to a simple plateau-gradient model. However, for larger hot spots with timescale ratios sufficiently less than unity the reaction behaviour is highly dependent on the smooth temperature profile contained within the core region.
NASA Technical Reports Server (NTRS)
Collinson, G. A.; Sibeck, David Gary; Boardsen, Scott A.; Moore, Tom; Barabash, S.; Masters, A.; Shane, N.; Slavin, J.A.; Coates, A.J.; Zhang, T. L.;
2012-01-01
We present a multi-instrument study of a hot flow anomaly (HFA) observed by the Venus Express spacecraft in the Venusian foreshock, on 22 March 2008, incorporating both Venus Express Magnetometer and Analyzer of Space Plasmas and Energetic Atoms (ASPERA) plasma observations. Centered on an interplanetary magnetic field discontinuity with inward convective motional electric fields on both sides, with a decreased core field strength, ion observations consistent with a flow deflection, and bounded by compressive heated edges, the properties of this event are consistent with those of HFAs observed at other planets within the solar system.
Porosity and Permeability Evolution Accompanying Hot fluid Injection into Diatomite, SUPRI TR-123
DOE Office of Scientific and Technical Information (OSTI.GOV)
Diabira, I.; Castanier, L.M.; Kovscek, A.R.
2001-04-19
An experimental study of silica dissolution was performed to probe the evolution of permeability and porosity in siliceous diatomite during hot fluid injection such as water or steam flooding. Two competing mechanisms were identified. Silica solubility in water at elevated temperature causes rock dissolution thereby increasing permeability; however, the rock is mechanically weak leading to compressing of the solid matrix during injection. Permeability and porosity can decrease at the onset of fluid flow. A laboratory flow apparatus was designed and built to examine these processes in diatomite core samples.
Fabrication and characterization of tapered graphite/epoxy box beams
NASA Astrophysics Data System (ADS)
Yen, S.-C.; Gopal, P.; Dharani, L. R.
1993-04-01
Graphite/epoxy (T300/934) prepreg is used to fabricate tapered box beams with a taper angle of 2 deg between the top and bottom walls. The prepreg is cured on a segmented steel core using a hot-press. A screw arrangement is used to apply curing pressure in the horizontal direction, while the platens of the hot-press apply pressure in the vertical direction. The inplane bending stiffness of the beam is determined by 3-point bend test and is found to be in agreement with theory.
IRAS 23385 & 6053: A Prototype Massive Class O Object
NASA Technical Reports Server (NTRS)
Molinari, S.; Testi, L.; Brand, J.; Cesaroni, R.; Palla, F.
1998-01-01
The last few years have seen a rapid growth in observations aimed at identifying intermediate and high-mass star forming sites in a wide range of evolutionary stages ranging from Hot Cores to ultracompact regions, to proto-Ae/Be stars.
Hot hollow cathode gun assembly
Zeren, J.D.
1983-11-22
A hot hollow cathode deposition gun assembly includes a hollow body having a cylindrical outer surface and an end plate for holding an adjustable heat sink, the hot hollow cathode gun, two magnets for steering the plasma from the gun into a crucible on the heat sink, and a shutter for selectively covering and uncovering the crucible.
Developing a virtual community for health sciences library book selection: Doody's Core Titles.
Shedlock, James; Walton, Linda J
2006-01-01
The purpose of this article is to describe Doody's Core Titles in the Health Sciences as a new selection guide and a virtual community based on an effective use of online systems and to describe its potential impact on library collection development. The setting is the availability of health sciences selection guides. Participants include Doody Enterprise staff, Doody's Library Board of Advisors, content specialists, and library selectors. Resources include the online system used to create Doody's Core Titles along with references to complementary databases. Doody's Core Titles is described and discussed in relation to the literature of selection guides, especially in comparison to the Brandon/Hill selected lists that were published from 1965 to 2003. Doody's Core Titles seeks to fill the vacuum created when the Brandon/Hill lists ceased publication. Doody's Core Titles is a unique selection guide based on its method of creating an online community of experts to identify and score a core list of titles in 119 health sciences specialties and disciplines. The result is a new selection guide, now available annually, that will aid health sciences librarians in identifying core titles for local collections. Doody's Core Titles organizes the evaluation of core titles that are identified and recommended by content specialists associated with Doody's Book Review Service and library selectors. A scoring mechanism is used to create the selection of core titles, similar to the star rating system employed in other Doody Enterprise products and services.
48 CFR 925.7003 - Requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7003 Requirements. (a) For the acquisition of nuclear hot cell services under the conditions in paragraph (b) of this section, the selection...
48 CFR 925.7003 - Requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7003 Requirements. (a) For the acquisition of nuclear hot cell services under the conditions in paragraph (b) of this section, the selection...
48 CFR 925.7003 - Requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7003 Requirements. (a) For the acquisition of nuclear hot cell services under the conditions in paragraph (b) of this section, the selection...
48 CFR 925.7003 - Requirements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7003 Requirements. (a) For the acquisition of nuclear hot cell services under the conditions in paragraph (b) of this section, the selection...
48 CFR 925.7003 - Requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... FOREIGN ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7003 Requirements. (a) For the acquisition of nuclear hot cell services under the conditions in paragraph (b) of this section, the selection...
Qualification of APOLLO2 BWR calculation scheme on the BASALA mock-up
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vaglio-Gaudard, C.; Santamarina, A.; Sargeni, A.
2006-07-01
A new neutronic APOLLO2/MOC/SHEM/CEA2005 calculation scheme for BWR applications has been developed by the French 'Commissariat a l'Energie Atomique'. This scheme is based on the latest calculation methodology (accurate mutual and self-shielding formalism, MOC treatment of the transport equation) and the recent JEFF3.1 nuclear data library. This paper presents the experimental validation of this new calculation scheme on the BASALA BWR mock-up The BASALA programme is devoted to the measurements of the physical parameters of high moderation 100% MOX BWR cores, in hot and cold conditions. The experimental validation of the calculation scheme deals with core reactivity, fission rate maps,more » reactivity worth of void and absorbers (cruciform control blades and Gd pins), as well as temperature coefficient. Results of the analysis using APOLLO2/MOC/SHEM/CEA2005 show an overestimation of the core reactivity by 600 pcm for BASALA-Hot and 750 pcm for BASALA-Cold. Reactivity worth of gadolinium poison pins and hafnium or B{sub 4}C control blades are predicted by APOLLO2 calculation within 2% accuracy. Furthermore, the radial power map is well predicted for every core configuration, including Void configuration and Hf / B{sub 4}C configurations: fission rates in the central assembly are calculated within the {+-}2% experimental uncertainty for the reference cores. The C/E bias on the isothermal Moderator Temperature Coefficient, using the CEA2005 library based on JEFF3.1 file, amounts to -1.7{+-}03 pcm/ deg. C on the range 10 deg. C-80 deg. C. (authors)« less
Bruce, Caroline D; Fegely, Kurt A; Rajabi-Siahboomi, Ali R; McGinity, James W
2010-02-01
This study investigated the effect of aqueous film coating on the recrystallization of guaifenesin from acrylic, hot-melt extruded matrix tablets. After hot-melt extrusion, matrix tablets were film-coated with either hypromellose or ethylcellulose. The effects of the coating polymer, curing and storage conditions, polymer weight gain, and core guaifenesin concentration on guaifenesin recrystallization were investigated. The presence of either film coating on the guaifenesin-containing tablets was found to prolong the onset time of drug crystallization. The coating polymer was the most important factor determining the delay in the onset of crystallization, with the more hydrophilic polymer, hypromellose, having a higher solubilization potential for the guaifenesin and delaying crystallization for longer period (3 or 6 months in tablets stored at 40 degrees C or 25 degrees C, respectively) than the more hydrophobic ethylcellulose, which displayed a lower solubilization potential for guaifenesin (crystal growth on tablets cured for 2 hours at 60 degrees C occurred within 3 weeks, whereas uncoated tablets displayed surface crystal growth after 30 minutes). Crystal morphology was also affected by the film coating. Elevated temperatures during both curing and storage, incomplete film coalescence, and high core drug concentrations all contributed to an earlier onset of crystal growth.
Daniels, F.
1957-10-15
Gas-cooled solid-moderator type reactors wherein the fissionable fuel and moderator materials are each in the form of solid pebbles, or discrete particles, and are substantially homogeneously mixed in the proper proportion and placed within the core of the reactor are described. The shape of these discrete particles must be such that voids are present between them when mixed together. Helium enters the bottom of the core and passes through the voids between the fuel and moderator particles to absorb the heat generated by the chain reaction. The hot helium gas is drawn off the top of the core and may be passed through a heat exchanger to produce steam.
Code of Federal Regulations, 2010 CFR
2010-10-01
... ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7002 Policy. In selecting offer(s) for award of contracts for nuclear hot cell services, costs related to the decommissioning of nuclear facilities and...
Code of Federal Regulations, 2014 CFR
2014-10-01
... ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7002 Policy. In selecting offer(s) for award of contracts for nuclear hot cell services, costs related to the decommissioning of nuclear facilities and...
Code of Federal Regulations, 2012 CFR
2012-10-01
... ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7002 Policy. In selecting offer(s) for award of contracts for nuclear hot cell services, costs related to the decommissioning of nuclear facilities and...
Code of Federal Regulations, 2011 CFR
2011-10-01
... ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7002 Policy. In selecting offer(s) for award of contracts for nuclear hot cell services, costs related to the decommissioning of nuclear facilities and...
Code of Federal Regulations, 2013 CFR
2013-10-01
... ACQUISITION Acquisition of Nuclear Hot Cell Services 925.7002 Policy. In selecting offer(s) for award of contracts for nuclear hot cell services, costs related to the decommissioning of nuclear facilities and...
1987-12-01
developed for a large percentage of the participants in the Summer Faculty Research Program in 1979-1983 period through an AFOSR Minigrant Program . On 1...Analysis of a Bimodal Nuclear Rocket Core by Dav,, C. Carpenter ABSTRACT The framework for a general purpose finite element analysis code was developed ...to study the 2-D temperature distribution in a hot-channel S hexagonal fuel element in the core of a bimodal nuclear’ rocket. Prelim- inary thermal
CCC7-119 Reactive Molecular Dynamics Simulations of Hot Spot Growth in Shocked Energetic Materials
DOE Office of Scientific and Technical Information (OSTI.GOV)
Thompson, Aidan P.
2015-03-01
The purpose of this work is to understand how defects control initiation in energetic materials used in stockpile components; Sequoia gives us the core-count to run very large-scale simulations of up to 10 million atoms and; Using an OpenMP threaded implementation of the ReaxFF package in LAMMPS, we have been able to get good parallel efficiency running on 16k nodes of Sequoia, with 1 hardware thread per core.
Review of coaxial flow gas core nuclear rocket fluid mechanics
NASA Technical Reports Server (NTRS)
Weinstein, H.
1976-01-01
Almost all of the fluid mechanics research associated with the coaxial flow gas core reactor ended abruptly with the interruption of NASA's space nuclear program because of policy and budgetary considerations in 1973. An overview of program accomplishments is presented through a review of the experiments conducted and the analyses performed. Areas are indicated where additional research is required for a fuller understanding of cavity flow and of the factors which influence cold and hot flow containment. A bibliography is included with graphic material.
Self-defrosting recuperative air-to-air heat exchanger
Drake, R.L.
1993-12-28
A heat exchanger is described which includes a stationary spirally or concentrically wound heat exchanger core with rotating baffles on upper and lower ends thereof. The rotating baffles include rotating inlets and outlets which are in communication with respective fixed inlets and outlets via annuli. The rotation of the baffles causes a concurrent rotation of the temperature distribution within the stationary exchanger core, thereby preventing frost build-up in some applications and preventing the formation of hot spots in other applications. 3 figures.
In situ recovery of water from dormant comet cores and CI carbonaceous chondrites
NASA Astrophysics Data System (ADS)
Kuck, David L.
A model is presented for the derivation of water and volatiles from drill holes in dormant comet cores and class CI or CM asteroids, as in the Frasch process applied to sulfur mines. Hot gas is injected to melt ice, as well as to blow water and/or steam from the hole; heating to over 393 K removes six of the seven water molecules from epsomite, and melts elemental sulfur; a temperature above 573 K can drive water from hydrated phylosilicates.
NASA Astrophysics Data System (ADS)
Ronald, Terence M. F.
1991-12-01
Structural materials for the NASP X-30 experimental vehicle are briefly reviewed including titanium alloys, titanium-based metal-matrix composites, carbon-carbon composites, ceramic-matrix composites, and copper-matrix composites. Areas of application of these materials include the airframe where these materials would be used as lightweight skin panels for honeycomb-core, truss-core, or integrally stiffened thin sheet configuration; and the engine, where they would be used in the hot gas path of the ramjet/scramjet, and in the inlet and nozzle areas.
DOT National Transportation Integrated Search
2013-11-01
Current roadway quality control and quality acceptance (QC/QA) procedures for the Louisiana Department of Transportation and : Development (LADOTD) include coring for thickness, density, and air voids in hot mix asphalt (HMA) pavements and thickness ...
The Helix Nebula: Unraveling at the Seams
2012-10-03
This image from NASA Spitzer and GALEX shows the Helix nebula, a dying star throwing a cosmic tantrum. In death, the star dusty outer layers are unraveling into space, glowing from the intense UV radiation being pumped out by the hot stellar core.
Hot-Electron-Induced Device Degradation during Gate-Induced Drain Leakage Stress
NASA Astrophysics Data System (ADS)
Kim, Kwang-Soo; Han, Chang-Hoon; Lee, Jun-Ki; Kim, Dong-Soo; Kim, Hyong-Joon; Shin, Joong-Shik; Lee, Hea-Beoum; Choi, Byoung-Deog
2012-11-01
We studied the interface state generation and electron trapping by hot electrons under gate-induced drain leakage (GIDL) stress in p-type metal oxide semiconductor field-effect transistors (P-MOSFETs), which are used as the high-voltage core circuit of flash memory devices. When negative voltage was applied to a drain in the off-state, a GIDL current was generated, but when high voltage was applied to the drain, electrons had a high energy. The hot electrons produced the interface state and electron trapping. As a result, the threshold voltage shifted and the off-state leakage current (trap-assisted drain junction leakage current) increased. On the other hand, electron trapping mitigated the energy band bending near the drain and thus suppressed the GIDL current generation.
Developing a virtual community for health sciences library book selection: Doody's Core Titles
Shedlock, James; Walton, Linda J.
2006-01-01
Purpose: The purpose of this article is to describe Doody's Core Titles in the Health Sciences as a new selection guide and a virtual community based on an effective use of online systems and to describe its potential impact on library collection development. Setting/Participants/Resources: The setting is the availability of health sciences selection guides. Participants include Doody Enterprise staff, Doody's Library Board of Advisors, content specialists, and library selectors. Resources include the online system used to create Doody's Core Titles along with references to complementary databases. Brief Description: Doody's Core Titles is described and discussed in relation to the literature of selection guides, especially in comparison to the Brandon/Hill selected lists that were published from 1965 to 2003. Doody's Core Titles seeks to fill the vacuum created when the Brandon/Hill lists ceased publication. Doody's Core Titles is a unique selection guide based on its method of creating an online community of experts to identify and score a core list of titles in 119 health sciences specialties and disciplines. Results/Outcome: The result is a new selection guide, now available annually, that will aid health sciences librarians in identifying core titles for local collections. Evaluation Method: Doody's Core Titles organizes the evaluation of core titles that are identified and recommended by content specialists associated with Doody's Book Review Service and library selectors. A scoring mechanism is used to create the selection of core titles, similar to the star rating system employed in other Doody Enterprise products and services. PMID:16404471
NASA Astrophysics Data System (ADS)
de Luca, Massimo
The primary goal of the PRISMAS Herschel key program is the spectroscopic study of key molecular lines towards bright Galactic star-forming regions and the diffuse interstellar clouds distributed along the lines of sight. Models of the source emission and absorption spectra have been constructed with CASSIS, based on 1) observational evidence in comparable environments, 2) warm-up chemical models with gas-grain networks, and 3) ground-based spectra of various molecules in the target sources obtained at the IRAM 30m telescope. These models include contributions from the hot core, its parental molecular cloud and the foreground diffuse inter-stellar matter. The considerable complexity of the hot core chemistry, together with the huge amount of information buried in the spectra, often prevents a straightforward interpretation of the data without the help simulations. This is particularly true for the largely unexplored wavelength range of HIFI. In this contribution, we compare HIFI and IRAM observations to our models, in order to either consolidate present day assumptions and knowledge of these environments, or to highlight the model limitations, poorly understood physical and chemical conditions or unexpected abundances. We pay particular attention to the ground state tran-sitions of the most important hydrides, which the PRISMAS program has been designed for, though the HIFI spectra are expected to be rich in other molecules as well. List of Authors De Luca, M., Observatoire de Paris, Ecole Normale Supérieure and CNRS, FRANCE; Bell, T., CalTech, UNITED STATES; Coutens, A., CESR, FRANCE; Godard, B., IAS, FRANCE; Gupta, H., JPL, UNITED STATES; Mook-erjea, B., Tata Institute for Fundamental Research, INDIA; and the PRISMAS consortium, PRISMAS, FRANCE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sakai, Yusuke; Kobayashi, Kaori; Hirota, Tomoya, E-mail: kaori@sci.u-toyama.ac.jp, E-mail: tomoya.hirota@nao.ac.jp
2015-04-20
We recently reported the first identification of rotational transitions of methyl formate (HCOOCH{sub 3}) in the second torsionally excited state toward Orion Kleinmann-Low (KL), observed with the Nobeyama 45 m telescope. In combination with the identified transitions of methyl formate in the ground state and the first torsional excited state, it was found that there is a difference in rotational temperature and vibrational temperature, where the latter is higher. In this study, high spatial resolution analysis by using Atacama Large Millimeter/Submillimeter Array (ALMA) science verification data was carried out to verify and understand this difference. Toward the Compact Ridge, two differentmore » velocity components at 7.3 and 9.1 km s{sup −1} were confirmed, while a single component at 7.3 km s{sup −1} was identified toward the Hot Core. The intensity maps in the ground, first, and second torsional excited states have quite similar distributions. Using extensive ALMA data, we determined the rotational and vibrational temperatures for the Compact Ridge and Hot Core by the conventional rotation diagram method. The rotational temperature and vibrational temperatures agree for the Hot Core and for one component of the Compact Ridge. At the 7.3 km s{sup −1} velocity component for the Compact Ridge, the rotational temperature was found to be higher than the vibrational temperature. This is different from what we obtained from the results by using the single-dish observation. The difference might be explained by the beam dilution effect of the single-dish data and/or the smaller number of observed transitions within the limited range of energy levels (≤30 K) of E{sub u} in the previous study.« less
NASA Technical Reports Server (NTRS)
Wilson, R. B.; Banerjee, P. K.
1987-01-01
This Annual Status Report presents the results of work performed during the third year of the 3-D Inelastic Analysis Methods for Hot Sections Components program (NASA Contract NAS3-23697). The objective of the program is to produce a series of computer codes that permit more accurate and efficient three-dimensional analyses of selected hot section components, i.e., combustor liners, turbine blades, and turbine vanes. The computer codes embody a progression of mathematical models and are streamlined to take advantage of geometrical features, loading conditions, and forms of material response that distinguish each group of selected components.
Xia, Junfeng; Yue, Zhenyu; Di, Yunqiang; Zhu, Xiaolei; Zheng, Chun-Hou
2016-01-01
The identification of hot spots, a small subset of protein interfaces that accounts for the majority of binding free energy, is becoming more important for the research of drug design and cancer development. Based on our previous methods (APIS and KFC2), here we proposed a novel hot spot prediction method. For each hot spot residue, we firstly constructed a wide variety of 108 sequence, structural, and neighborhood features to characterize potential hot spot residues, including conventional ones and new one (pseudo hydrophobicity) exploited in this study. We then selected 3 top-ranking features that contribute the most in the classification by a two-step feature selection process consisting of minimal-redundancy-maximal-relevance algorithm and an exhaustive search method. We used support vector machines to build our final prediction model. When testing our model on an independent test set, our method showed the highest F1-score of 0.70 and MCC of 0.46 comparing with the existing state-of-the-art hot spot prediction methods. Our results indicate that these features are more effective than the conventional features considered previously, and that the combination of our and traditional features may support the creation of a discriminative feature set for efficient prediction of hot spots in protein interfaces. PMID:26934646
Electron-Phonon Coupling and Resonant Relaxation from 1D and 1P States in PbS Quantum Dots.
Kennehan, Eric R; Doucette, Grayson S; Marshall, Ashley R; Grieco, Christopher; Munson, Kyle T; Beard, Matthew C; Asbury, John B
2018-05-31
Observations of the hot-phonon bottleneck, which is predicted to slow the rate of hot carrier cooling in quantum confined nanocrystals, have been limited to date for reasons that are not fully understood. We used time-resolved infrared spectroscopy to directly measure higher energy intraband transitions in PbS colloidal quantum dots. Direct measurements of these intraband transitions permitted detailed analysis of the electronic overlap of the quantum confined states that may influence their relaxation processes. In smaller PbS nanocrystals, where the hot-phonon bottleneck is expected to be most pronounced, we found that relaxation of parity selection rules combined with stronger electron-phonon coupling led to greater spectral overlap of transitions among the quantum confined states. This created pathways for fast energy transfer and relaxation that may bypass the predicted hot-phonon bottleneck. In contrast, larger, but still quantum confined nanocrystals did not exhibit such relaxation of the parity selection rules and possessed narrower intraband states. These observations were consistent with slower relaxation dynamics that have been measured in larger quantum confined systems. These findings indicated that, at small radii, electron-phonon interactions overcome the advantageous increase in energetic separation of the electronic states for PbS quantum dots. Selection of appropriately sized quantum dots, which minimize spectral broadening due to electron-phonon interactions while maximizing electronic state separation, is necessary to observe the hot-phonon bottleneck. Such optimization may provide a framework for achieving efficient hot carrier collection and multiple exciton generation.
Evolution of high-mass star-forming regions .
NASA Astrophysics Data System (ADS)
Giannetti, A.; Leurini, S.; Wyrowski, F.; Urquhart, J.; König, C.; Csengeri, T.; Güsten, R.; Menten, K. M.
Observational identification of a coherent evolutionary sequence for high-mass star-forming regions is still missing. We use the progressive heating of the gas caused by the feedback of high-mass young stellar objects to prove the statistical validity of the most common schemes used to observationally define an evolutionary sequence for high-mass clumps, and identify which physical process dominates in the different phases. From the spectroscopic follow-ups carried out towards the TOP100 sample between 84 and 365 km s^-1 giga hertz, we selected several multiplets of CH3CN, CH3CCH, and CH3OH lines to derive the physical properties of the gas in the clumps along the evolutionary sequence. We demonstrate that the evolutionary sequence is statistically valid, and we define intervals in L/M separating the compression, collapse and accretion, and disruption phases. The first hot cores and ZAMS stars appear at L/M≈10usk {L_ȯ}msun-1
Resolving hot spot microstructure using x-ray penumbral imaging (invited)
NASA Astrophysics Data System (ADS)
Bachmann, B.; Hilsabeck, T.; Field, J.; Masters, N.; Reed, C.; Pardini, T.; Rygg, J. R.; Alexander, N.; Benedetti, L. R.; Döppner, T.; Forsman, A.; Izumi, N.; LePape, S.; Ma, T.; MacPhee, A. G.; Nagel, S.; Patel, P.; Spears, B.; Landen, O. L.
2016-11-01
We have developed and fielded x-ray penumbral imaging on the National Ignition Facility in order to enable sub-10 μm resolution imaging of stagnated plasma cores (hot spots) of spherically shock compressed spheres and shell implosion targets. By utilizing circular tungsten and tantalum apertures with diameters ranging from 20 μm to 2 mm, in combination with image plate and gated x-ray detectors as well as imaging magnifications ranging from 4 to 64, we have demonstrated high-resolution imaging of hot spot plasmas at x-ray energies above 5 keV. Here we give an overview of the experimental design criteria involved and demonstrate the most relevant influences on the reconstruction of x-ray penumbral images, as well as mitigation strategies of image degrading effects like over-exposed pixels, artifacts, and photon limited source emission. We describe experimental results showing the advantages of x-ray penumbral imaging over conventional Fraunhofer and photon limited pinhole imaging and showcase how internal hot spot microstructures can be resolved.
Body temperature modulates the antioxidant and acute immune responses to exercise.
Mestre-Alfaro, Antonia; Ferrer, Miguel D; Banquells, Montserrat; Riera, Joan; Drobnic, Franchek; Sureda, Antoni; Tur, Josep A; Pons, Antoni
2012-06-01
The aim of this study was to determine the effects of whole body heat in combination with exercise on the oxidative stress and acute phase immune response. Nine male endurance-trained athletes voluntarily performed two running bouts of 45 minutes at 75-80% of VO(2max) in a climatic chamber in two conditions: cold and hot humid environment. Leukocyte, neutrophil and basophil counts significantly rose after exercise in both environments; it was significantly greater in the hot environment. Lymphocyte and neutrophil antioxidant enzyme activities and carbonyl index significantly increased or decreased after exercise only in the hot environment, respectively. The lymphocytes expression of catalase, Hsp72 and CuZn-superoxide dismutase was increased in the hot environment and Sirt3 in the cold environment, mainly during recovery. In conclusion, the increased core body temperature results in the acute phase immune response associated to intense exercise and in the immune cell adaptations to counteract the oxidative stress situation.
Kelley Hot Spring Geothermal Project: Kelly Hot Spring Agricultural Center conceptual design
DOE Office of Scientific and Technical Information (OSTI.GOV)
Longyear, A.B.
1980-06-01
The proposed core activity in the Kelly Hot Spring Agricultural Center is a nominal 1200 sow swine raising complex. The swine raising is to be a totally confined operation for producing premium pork in controlled environment facilities that utilize geothermal energy. The complex will include a feedmill for producing the various feed formulae required for the animals from breeding through gestation, farrowing, nursery, growing and finishing. The market animals are shipped live by truck to slaughter in Modesto, California. A complete waste management facility will include manure collection from all raising areas, transport via a water flush sysem to methanemore » (biogas) generators, manure separation, settling ponds and disposition of the surplus agricultural quality water. The design is based upon the best commercial practices in confined swine raising in the US today. The most unique feature of the facility is the utilization of geothermal hot water for space heating and process energy throughout the complex.« less
Hot Gas and AGN Feedback in Galaxies and Nearby Groups
NASA Astrophysics Data System (ADS)
Jones, Christine; Forman, William; Bogdan, Akos; Randall, Scott; Kraft, Ralph; Churazov, Eugene
2013-07-01
Massive galaxies harbor a supermassive black hole at their centers. At high redshifts, these galaxies experienced a very active quasar phase, when, as their black holes grew by accretion, they produced enormous amounts of energy. At the present epoch, these black holes still undergo occasional outbursts, although the mode of their energy release is primarily mechanical rather than radiative. The energy from these outbursts can reheat the cooling gas in the galaxy cores and maintain the red and dead nature of the early-type galaxies. These outbursts also can have dramatic effects on the galaxy-scale hot coronae found in the more massive galaxies. We describe research in three areas related to the hot gas around galaxies and their supermassive black holes. First we present examples of galaxies with AGN outbursts that have been studied in detail. Second, we show that X-ray emitting low-luminosity AGN are present in 80% of the galaxies studied. Third, we discuss the first examples of extensive hot gas and dark matter halos in optically faint galaxies.
Resolving hot spot microstructure using x-ray penumbral imaging (invited).
Bachmann, B; Hilsabeck, T; Field, J; Masters, N; Reed, C; Pardini, T; Rygg, J R; Alexander, N; Benedetti, L R; Döppner, T; Forsman, A; Izumi, N; LePape, S; Ma, T; MacPhee, A G; Nagel, S; Patel, P; Spears, B; Landen, O L
2016-11-01
We have developed and fielded x-ray penumbral imaging on the National Ignition Facility in order to enable sub-10 μm resolution imaging of stagnated plasma cores (hot spots) of spherically shock compressed spheres and shell implosion targets. By utilizing circular tungsten and tantalum apertures with diameters ranging from 20 μm to 2 mm, in combination with image plate and gated x-ray detectors as well as imaging magnifications ranging from 4 to 64, we have demonstrated high-resolution imaging of hot spot plasmas at x-ray energies above 5 keV. Here we give an overview of the experimental design criteria involved and demonstrate the most relevant influences on the reconstruction of x-ray penumbral images, as well as mitigation strategies of image degrading effects like over-exposed pixels, artifacts, and photon limited source emission. We describe experimental results showing the advantages of x-ray penumbral imaging over conventional Fraunhofer and photon limited pinhole imaging and showcase how internal hot spot microstructures can be resolved.
Managing Hot Flushes in Menopausal Women: A Review.
Mallhi, Tauqeer Hussain; Khan, Yusra Habib; Khan, Amer Hayat; Mahmood, Qaisar; Khalid, Syed Haroon; Saleem, Mohammad
2018-06-01
Hot flushes during menopause are distressing for women and result in poor quality of life. Purpose of the current review was to evaluate the available treatment modalities that should be utilised for the management of hot flushes. Menopause refers to last menses of women life and can be declared after amenorrhea of 12 months. Vasomotor symptoms including hot flushes and night sweats are common after menopause, affecting almost 50 - 85% women older than 45 years. The mean increment in core body and skin temperature is 0.5°C and 0.25 - 3°C during a hot flush attack. Low level of estrogen during menopause and its association in triggering episodes of hot flushes, is still under debate. The most accepted hypothesis is a narrowing of the thermoneutral zone (TNZ) triggered by estrogen fluctuations. Although, hormone replacement therapy (HRT) remains the standard treatment for the alleviation of such symptoms, incidence of life threatening side effects restrained medical professionals from its use. Complications associated with the use of HRT can be avoided by appropriate evaluation of patients before initiating therapy. Several guidelines have also recommended HRT (estrogen and progesterone) to be safe for up to a period of seven years. Both hormonal and non-hormonal treatments are used for the management of hot flushes. Since hot flushes are the least appreciated and neglected complication of menopause, current review provides detailed information on its background, pathophysiology and management, and emphasises the need of its treatment.
NASA Astrophysics Data System (ADS)
Li, F.; Zhang, C.; Wang, S.; Klotz, M. G.; Dong, H.; Li, W.
2013-12-01
Branched glycerol dialkyl glycerol tetraethers (bGDGTs) are considered to be produced by bacteria that are predominantly found in soils and peat bogs. Recently, however, in situ production of bGDGTs is reported from a terrestrial hot spring in the Great Basin. In this study, we analyzed water chemistry, bacterial lipids, and pyrosequencing data from 37 Tibetan hot springs in order to evaluate the linkage between biological sources, metabolic processes and the distribution of bGDGTs. Analyses of absolute and relative concentrations of intact polar- and core bGDGTs (IP-bGDGTs and C-bGDGTs) suggest that the bGDGTs are predominantly produced in situ in Tibetan hot springs. Cluster analysis separated the hot spring samples into three major groups, which showed significant relationships between bGDGTs and concentrations of ammonia, nitrite or nitrate. The nirS gene abundance also correlated significantly with bGDGTs. These results indicate that the bGDGT-producing organisms may be involved in nitrogen metabolism in the Tibetan hot springs. Pyrosequencing analysis identified eight phyla of Bacteria (Acidobacteria, Bacteroidetes, Chlorobi, Firmicutes, Nitrospirae, Proteobacteria, Verrucomicrobia and Spirochetes) that may be potential sources of bGDGTs based on significant correlations of these organisms with the distribution of different bGDGTs. Representatives of these phyla have been implicated in nitrogen oxide transformations in many diverse environments including hot springs. Overall, our results suggest that bacteria producing bGDGTs may play an important role in nitrogen cycle in the Tibetan hot springs.
DOT National Transportation Integrated Search
2013-11-01
Current roadway quality control and quality acceptance (QC/QA) procedures for the Louisiana Department of Transportation and Development : (LADOTD) include coring for thickness, density, and air voids in hot mix asphalt (HMA) pavements and thickness ...
NASA Technical Reports Server (NTRS)
Mehta, Manish; Seaford, Mark; Kovarik, Brian; Dufrene, Aaron; Solly, Nathan; Kirchner, Robert; Engel, Carl D.
2014-01-01
The Space Launch System (SLS) base heating test is broken down into two test programs: (1) Pathfinder and (2) Main Test. The Pathfinder Test Program focuses on the design, development, hot-fire test and performance analyses of the 2% sub-scale SLS core-stage and booster element propulsion systems. The core-stage propulsion system is composed of four gaseous oxygen/hydrogen RS-25D model engines and the booster element is composed of two aluminum-based model solid rocket motors (SRMs). The first section of the paper discusses the motivation and test facility specifications for the test program. The second section briefly investigates the internal flow path of the design. The third section briefly shows the performance of the model RS-25D engines and SRMs for the conducted short duration hot-fire tests. Good agreement is observed based on design prediction analysis and test data. This program is a challenging research and development effort that has not been attempted in 40+ years for a NASA vehicle.
Magneto-plasmonic Au-Coated Co nanoparticles synthesized via hot-injection method
NASA Astrophysics Data System (ADS)
Souza, João B., Jr.; Varanda, Laudemir C.
2018-02-01
A synthetic procedure is described for the obtaining of superparamagnetic Co nanoparticles (NPs) via hot-injection method in the presence of sodium borohydride. The Co NPs obtained have an average diameter of 5.3 nm and saturation magnetization of 115 emu g-1. A modified Langevin equation is fitted to the magnetization curves using a log-normal distribution for the particle diameter and an effective field to account for dipolar interactions. The calculated magnetic diameter of the Co NPs is 0.6 nm smaller than TEM-derived values, implying a magnetic dead layer of 0.3 nm. The magnetic core is coated with Au to prevent oxidation, resulting in water-stable magneto-plasmonic Co/Au core/shell NPs with saturation of 71.6 emu g-1. The coating adds a localized surface plasmon resonance property with absorbance in the so-called ‘therapeutic window’ (690-900 nm), suitable for biomedical applications. It is suggested that these multifunctional NPs are distinguished as a potential platform for applied and fundamental research.
The Origin of Molecular Clouds in Central Galaxies
NASA Astrophysics Data System (ADS)
Pulido, F. A.; McNamara, B. R.; Edge, A. C.; Hogan, M. T.; Vantyghem, A. N.; Russell, H. R.; Nulsen, P. E. J.; Babyk, I.; Salomé, P.
2018-02-01
We present an analysis of 55 central galaxies in clusters and groups with molecular gas masses and star formation rates lying between {10}8 {and} {10}11 {M}ȯ and 0.5 and 270 {M}ȯ {{yr}}-1, respectively. Molecular gas mass is correlated with star formation rate, Hα line luminosity, and central atmospheric gas density. Molecular gas is detected only when the central cooling time or entropy index of the hot atmosphere falls below ∼1 Gyr or ∼35 keV cm2, respectively, at a (resolved) radius of 10 kpc. These correlations indicate that the molecular gas condensed from hot atmospheres surrounding the central galaxies. We explore the origins of thermally unstable cooling by evaluating whether molecular gas becomes prevalent when the minimum of the cooling to free-fall time ratio ({t}{cool}/{t}{ff}) falls below ∼10. We find that (1) molecular gas-rich systems instead lie between 10< \\min ({t}{cool}/{t}{ff})< 25, where {t}{cool}/{t}{ff}=25 corresponds approximately to cooling time and entropy thresholds of 1 Gyr and 35 {keV} {{cm}}2, respectively; (2) \\min ({t}{cool}/{t}{ff}) is uncorrelated with molecular gas mass and jet power; and (3) the narrow range 10< \\min ({t}{cool}/{t}{ff})< 25 can be explained by an observational selection effect, although a real physical effect cannot be excluded. These results and the absence of isentropic cores in cluster atmospheres are in tension with models that assume thermal instability ensues from linear density perturbations in hot atmospheres when {t}{cool}/{t}{ff}≲ 10. Some of the molecular gas may instead have condensed from atmospheric gas lifted outward by buoyantly rising X-ray bubbles or by dynamically induced uplift (e.g., mergers, sloshing).
Phosphine-free synthesis and characterization of type-II ZnSe/CdS core-shell quantum dots
NASA Astrophysics Data System (ADS)
Ghasemzadeh, Roghayyeh; Armanmehr, Mohammad Hasan; Abedi, Mohammad; Fateh, Davood Sadeghi; Bahreini, Zaker
2018-01-01
A phosphine-free route for synthesis of type-II ZnSe/CdS core-shell quantum dots, using green, low cost and environmentally friendly reagents and phosphine-free solvents such as 1-octadecene (ODE) and liquid paraffin has been reported. Hot-injection technique has been used for the synthesis of ZnSe core quantum dots. The CdS shell quantum dots prepared by reaction of CdO precursor and S powder in 1-octadecene (ODE). The ZnSe/CdS core-shell quantum dots were synthesized via successive ion layer adsorption and reaction (SILAR) technique. The characterization of produced quantum dots were performed by absorption and fluorescence spectroscopy, X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDX) and transmission electron microscopy (TEM). The results showed the formation of type-II ZnSe/CdS core-shell quantum dots with FWHM 32 nm and uniform size distribution.
Core assembly storage structure
Jones, Jr., Charles E.; Brunings, Jay E.
1988-01-01
A structure for the storage of core assemblies from a liquid metal-cooled nuclear reactor. The structure comprises an enclosed housing having a substantially flat horizontal top plate, a bottom plate and substantially vertical wall members extending therebetween. A plurality of thimble members extend downwardly through the top plate. Each thimble member is closed at its bottom end and has an open end adjacent said top plate. Each thimble member has a length and diameter greater than that of the core assembly to be stored therein. The housing is provided with an inlet duct for the admission of cooling air and an exhaust duct for the discharge of air therefrom, such that when hot core assemblies are placed in the thimbles, the heat generated will by convection cause air to flow from the inlet duct around the thimbles and out the exhaust duct maintaining the core assemblies at a safe temperature without the necessity of auxiliary powered cooling equipment.
The Origin of Hot Subluminous Horizontal-Branch Stars in (omega) Centauri and NGC 2808
NASA Technical Reports Server (NTRS)
Sweigart, Allen V.; Brown, Thomas M.; Lanz, Thierry; Landsman, Wayne B.; Hubeny, Ivan
2001-01-01
Hot subluminous stars lying up to 0.7 mag below the extreme horizontal branch (EHB) are found in the ultraviolet (UV) color magnitude diagrams of both (omega) Cen and NGC 2808. In order to explore the evolutionary status of these subluminous stars, we have evolved a set of low-mass stars continuously from the main sequence through the helium-core flash to the HB (horizontal branch) for a wide range in the mass loss along the red-giant branch (RGB). Stars with the largest mass loss evolve off the RGB to high effective temperatures before igniting helium in their cores. Our results indicate that the subluminous EHB stars, as well as the gap within the EHB of NGC 2808, can be explained if these stars undergo a late helium-core flash while descending the white-dwarf cooling curve. Under these conditions the convection zone produced by the helium flash will penetrate into the stellar envelope, thereby mixing most, if not all, of the envelope hydrogen into the hot helium-burning interior, where it is rapidly consumed. This phenomenon is analogous to the 'born-again' scenario for producing hydrogen-deficient stars following a very late helium-shell flash. This 'flash mixing' of the stellar envelope greatly enhances the envelope helium and carbon abundances and, as a result, leads to a discontinuous jump in the HB effective temperature. We argue that the EHB gap in NGC 2808 is associated with this theoretically predicted dichotomy in the HB morphology. Using new helium- and carbon-rich stellar atmospheres, we show that these changes in the envelope abundances of the flash-mixed stars will suppress the UV flux by the amount needed to explain the hot subluminous EHB stars in (omega) Cen and NGC 2808. Moreover, we demonstrate that models without flash mixing lie, at most, only approximately 0.1 mag below the EHB, and hence fail to explain the observations. Flash mixing may also provide a new evolutionary channel for producing the high gravity, helium-rich sdO and sdB stars.
Dark Matter Core Defies Explanation
2017-12-08
NASA image release March 2, 2012 This composite image shows the distribution of dark matter, galaxies, and hot gas in the core of the merging galaxy cluster Abell 520, formed from a violent collision of massive galaxy clusters. The natural-color image of the galaxies was taken with NASA's Hubble Space Telescope and with the Canada-France-Hawaii Telescope in Hawaii. Superimposed on the image are "false-colored" maps showing the concentration of starlight, hot gas, and dark matter in the cluster. Starlight from galaxies, derived from observations by the Canada-France-Hawaii Telescope, is colored orange. The green-tinted regions show hot gas, as detected by NASA's Chandra X-ray Observatory. The gas is evidence that a collision took place. The blue-colored areas pinpoint the location of most of the mass in the cluster, which is dominated by dark matter. Dark matter is an invisible substance that makes up most of the universe's mass. The dark-matter map was derived from the Hubble Wide Field Planetary Camera 2 observations, by detecting how light from distant objects is distorted by the cluster galaxies, an effect called gravitational lensing. The blend of blue and green in the center of the image reveals that a clump of dark matter resides near most of the hot gas, where very few galaxies are found. This finding confirms previous observations of a dark-matter core in the cluster. The result could present a challenge to basic theories of dark matter, which predict that galaxies should be anchored to dark matter, even during the shock of a collision. Abell 520 resides 2.4 billion light-years away. To read more go to: www.nasa.gov/mission_pages/hubble/science/dark-matter-cor... Credit: NASA, ESA, CFHT, CXO, M.J. Jee (University of California, Davis), and A. Mahdavi (San Francisco State University) NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
ATLASGAL-selected massive clumps in the inner Galaxy. V. Temperature structure and evolution
NASA Astrophysics Data System (ADS)
Giannetti, A.; Leurini, S.; Wyrowski, F.; Urquhart, J.; Csengeri, T.; Menten, K. M.; König, C.; Güsten, R.
2017-07-01
Context. Observational identification of a solid evolutionary sequence for high-mass star-forming regions is still missing. Spectroscopic observations give the opportunity to test possible schemes and connect the phases identified to physical processes. Aims: We aim to use the progressive heating of the gas caused by the feedback of high-mass young stellar objects to prove the statistical validity of the most common schemes used to observationally define an evolutionary sequence for high-mass clumps, and characterise the sensitivity of different tracers to this process. Methods: From the spectroscopic follow-ups carried out towards submillimeter continuum (dust) emission-selected massive clumps (the ATLASGAL TOP100 sample) with the IRAM 30 m, Mopra, and APEX telescopes between 84 GHz and 365 GHz, we selected several multiplets of CH3CN, CH3CCH, and CH3OH emission lines to derive and compare the physical properties of the gas in the clumps along the evolutionary sequence, fitting simultaneously the large number of lines that these molecules have in the observed band. Our findings are compared with results obtained from optically thin CO isotopologues, dust, and ammonia from previous studies on the same sample. Results: The chemical properties of each species have a major role on the measured physical properties. Low temperatures are traced by ammonia, methanol, and CO (in the early phases), the warm and dense envelope can be probed with CH3CN, CH3CCH, and, in evolved sources where CO is abundant in the gas phase, via its optically thin isotopologues. CH3OH and CH3CN are also abundant in the hot cores, and we suggest that their high-excitation transitions are good tools to study the kinematics in the hot gas associated with the inner envelope surrounding the young stellar objects that these clumps are hosting. All tracers show, to different degrees according to their properties, progressive warming with evolution. The relation between gas temperature and the luminosity-to-mass (L/M) ratio is reproduced by a simple toy model of a spherical, internally heated clump. Conclusions: The evolutionary sequence defined for the clumps is statistically valid and we could identify the physical processes dominating in different intervals of L/M. For L/M ≾ 2 L⊙M⊙-1 a large quantity of the gas is still accumulated and compressed at the bottom of the potential well. Between 2 L⊙M⊙-1 ≾ L/M ≾ 40 L⊙M⊙-1 the young stellar objects gain mass and increase in luminosity; the first hot cores hosting intermediate- or high-mass ZAMS stars appear around L/M 10 L⊙M⊙-1. Finally, for L/M ≳ 40 L⊙M⊙-1 Hii regions become common, showing that dissipation of the parental clump dominates. Tables from A.1 to A.8 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/603/A33
NASA Astrophysics Data System (ADS)
Kalenskii, S. V.; Shchurov, M. A.
2016-04-01
The results of spectral observations of the region of massive star formation L379IRS1 (IRAS18265-1517) are presented. The observations were carried out with the 30-m Pico Veleta radio telescope (Spain) at seven frequencies in the 1-mm, 2-mm, and 3-mm wavelength bands. Lines of 24 molecules were detected, from simple diatomic or triatomic species to complex eight- or nine-atom compounds such as CH3OCHO or CH3OCH3. Rotation diagrams constructed from methanol andmethyl cyanide lines were used to determine the temperature of the quiescent gas in this region, which is about 40-50 K. In addition to this warm gas, there is a hot component that is revealed through high-energy lines of methanol and methyl cyanide, molecular lines arising in hot regions, and the presence of H2O masers and Class II methanol masers at 6.7 GHz, which are also related to hot gas. One of the hot regions is probably a compact hot core, which is located near the southern submillimeter peak and is related to a group of methanol masers at 6.7 GHz. High-excitation lines at other positions may be associated with other hot cores or hot post-shock gas in the lobes of bipolar outflows. The rotation diagrams can be use to determine the column densities and abundances of methanol (10-9) and methyl cyanide (about 10-11) in the quiescent gas. The column densities of A- and E-methanol in L379IRS1 are essentually the same. The column densities of other observedmolecules were calculated assuming that the ratios of the molecular level abundances correspond to a temperature of 40 K. The molecular composition of the quiescent gas is close to that in another region of massive star formation, DR21(OH). The only appreciable difference is that the column density of SO2 in L379IRS1 is at least a factor of 20 lower than the value in DR21(OH). The SO2/CS and SO2/OCS abundance ratios, which can be used as chemical clocks, are lower in L379IRS1 than in DR21(OH), suggesting that L379IRS1 is probably younger than DR21(OH).
Hot spot-based design of small-molecule inhibitors for protein-protein interactions.
Guo, Wenxing; Wisniewski, John A; Ji, Haitao
2014-06-01
Protein-protein interactions (PPIs) are important targets for the development of chemical probes and therapeutic agents. From the initial discovery of the existence of hot spots at PPI interfaces, it has been proposed that hot spots might provide the key for developing small-molecule PPI inhibitors. However, there has been no review on the ways in which the knowledge of hot spots can be used to achieve inhibitor design, nor critical examination of successful examples. This Digest discusses the characteristics of hot spots and the identification of druggable hot spot pockets. An analysis of four examples of hot spot-based design reveals the importance of this strategy in discovering potent and selective PPI inhibitors. A general procedure for hot spot-based design of PPI inhibitors is outlined. Copyright © 2014 Elsevier Ltd. All rights reserved.
Head-out immersion in hot water increases serum BDNF in healthy males.
Kojima, Daisuke; Nakamura, Takeshi; Banno, Motohiko; Umemoto, Yasunori; Kinoshita, Tokio; Ishida, Yuko; Tajima, Fumihiro
2017-11-20
Brain-derived neurotrophic factor (BDNF) is an important neurotrophin. The present study investigated the effects of head-out water immersion (HOI) on serum BDNF concentrations. Eight healthy men performed 20 min head-out water immersion at 42 °C (hot-HOI) and 35 °C (neutral-HOI). These experimental trials were administered in a randomised order separated by at least 7 days. Venous blood samples were withdrawn at rest, immediately after the 20-min HOI, as well as at 15 and 30 min after the end of the HOI. Serum BDNF and S100β, plasma cortisol, platelet and monocyte counts, and core body temperature (T cb ) were measured. T cb was higher at the end of the hot-HOI and 15 min after hot-HOI (p < 0.01), but recovered to pre-HOI level at 30 min after hot-HOI. No change in T cb was recorded during neutral-HOI. BDNF level was higher (p < 0.05) at the end of the hot-HOI and at 15 min after the end of hot-HOI, and returned to the baseline at 30 min after hot-HOI. S100β, platelet count and monocyte count remained stable throughout the study. Cortisol level was lower at the end of the hot-HOI and returned to pre-HOI level during the recovery period. BDNF and S100β, cortisol, and platelet and monocyte counts did not change throughout the neutral-HOI study. The present findings suggested that the increase in BDNF during 20-min hot-HOI was induced by hyperthermia through enhanced production, rather than by changes in permeability of the blood-brain barrier (BBB), platelet clotting mechanisms or secretion from monocytes.
FROM HOT JUPITERS TO SUPER-EARTHS VIA ROCHE LOBE OVERFLOW
DOE Office of Scientific and Technical Information (OSTI.GOV)
Valsecchi, Francesca; Rasio, Frederic A.; Steffen, Jason H.
2014-09-20
Through tidal dissipation in a slowly spinning host star, the orbits of many hot Jupiters may decay down to the Roche limit. We expect that the ensuing mass transfer will be stable in most cases. Using detailed numerical calculations, we find that this evolution is quite rapid, potentially leading to the complete removal of the gaseous envelope in a few gigayears, and leaving behind an exposed rocky core (a {sup h}ot super-Earth{sup )}. Final orbital periods are quite sensitive to the details of the planet's mass-radius relation and to the effects of irradiation and photo-evaporation, but could be as shortmore » as a few hours or as long as several days. Our scenario predicts the existence of planets with intermediate masses ({sup h}ot Neptunes{sup )} that should be found precisely at their Roche limit and in the process of losing mass through Roche lobe overflow. The observed excess of small single-planet candidate systems observed by Kepler may also be the result of this process. If so, the properties of their host stars should track those of the hot Jupiters. Moreover, the number of systems that produced hot Jupiters could be two to three times larger than one would infer from contemporary observations.« less
Influence of smooth temperature variation on hotspot ignition
Reinbacher, Fynn; Regele, Jonathan David
2017-10-06
Autoignition in thermally stratified reactive mixtures originates in localised hotspots. The ignition behaviour is often characterised using linear temperature gradients and more recently constant temperature plateaus combined with temperature gradients. Acoustic timescale characterisation of plateau regions has been successfully used to characterise the type of mechanical disturbance that will be created from a plateau core ignition. This work combines linear temperature gradients with superelliptic cores in order to more accurately account for a local temperature maximum of finite size and the smooth temperature variation contained inside realistic hotspot centres. A one-step Arrhenius reaction is used to model a H 2–airmore » reactive mixture. Using the superelliptic approach a range of behaviours for temperature distributions are investigated by varying the temperature profile between the gradient only and plateau and gradient bounding cases. Each superelliptic case is compared to a respective plateau and gradient case where simple acoustic timescale characterisation may be performed. It is shown that hot spots equivalent with excitation-to-acoustic timescale ratios sufficiently greater than unity exhibit behaviour very similar to a simple plateau-gradient model. Furthermore, for larger hot spots with timescale ratios sufficiently less than unity the reaction behaviour is highly dependent on the smooth temperature profile contained within the core region.« less
Preparation of a novel lipid-core micelle using a low-energy emulsification method.
Fritz, Hans F; Ortiz, Andrea C; Velaga, Sitaram P; Morales, Javier O
2018-04-16
High-energy methods for the manufacturing of nanomedicines are widely used; however, interest in low-energy methods is increasing due to their simplicity, better control over the process, and energy-saving characteristics during upscaling. Here, we developed a novel lipid-core micelle (LCM) as a nanocarrier to encapsulate a poorly water-soluble drug, nifedipine (NFD), by hot-melt emulsification, a low-energy method. LCMs are self-assembling colloidal particles composed of a hydrophobic core and a hydrophilic shell. Hybrid materials, such as Gelucire 44/14, are thus excellent candidates for their preparation. We characterized the obtained nanocarriers for their colloidal properties, drug loading and encapsulation efficiency, liquid state, stability, and drug release. The low-energy method hot-melt emulsification was successfully adapted for the manufacturing of small and narrowly dispersed LCMs. The obtained LCMs had a small average size of ~ 11 nm and a narrow polydispersity index (PDI) of 0.228. These nanocarriers were able to increase the amount of NFD dispersible in water more than 700-fold. Due to their sustained drug release profile and the PEGylation of Gelucire 44/14, these nanocarriers represent an excellent starting point for the development of drug delivery systems designed for long circulation times and passive targeting.
Externally Heated Protostellar Cores in the Ophiuchus Star-Forming Region
NASA Technical Reports Server (NTRS)
Lindberg, Johan E.; Charnley, Steven B.; Jorgensen, Jes K.; Cordiner, Martin A.; Bjerkeli, Per
2017-01-01
We present APEX 218 GHz observations of molecular emission in a complete sample of embedded protostars in the Ophiuchus star-forming region. To study the physical properties of the cores, we calculate H2CO and c-C3H2 rotational temperatures, both of which are good tracers of the kinetic temperature of the molecular gas. We find that the H2CO temperatures range between 16K and 124K, with the highest H2CO temperatures toward the hot corino source IRAS 16293-2422 (69-124 K) and the sources in the rho Oph A cloud (23-49 K) located close to the luminous Herbig Be star S1, which externally irradiates the rho Oph A cores. On the other hand, the c-C3H2 rotational temperature is consistently low (7-17 K) in all sources. Our results indicate that the c-C3H2 emission is primarily tracing more shielded parts of the envelope whereas the H2CO emission (at the angular scale of the APEX beam; 3600 au in Ophiuchus) mainly traces the outer irradiated envelopes, apart from in IRAS?16293-2422, where the hot corino emission dominates. In some sources, a secondary velocity component is also seen, possibly tracing the molecular outflow.
Influence of smooth temperature variation on hotspot ignition
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reinbacher, Fynn; Regele, Jonathan David
Autoignition in thermally stratified reactive mixtures originates in localised hotspots. The ignition behaviour is often characterised using linear temperature gradients and more recently constant temperature plateaus combined with temperature gradients. Acoustic timescale characterisation of plateau regions has been successfully used to characterise the type of mechanical disturbance that will be created from a plateau core ignition. This work combines linear temperature gradients with superelliptic cores in order to more accurately account for a local temperature maximum of finite size and the smooth temperature variation contained inside realistic hotspot centres. A one-step Arrhenius reaction is used to model a H 2–airmore » reactive mixture. Using the superelliptic approach a range of behaviours for temperature distributions are investigated by varying the temperature profile between the gradient only and plateau and gradient bounding cases. Each superelliptic case is compared to a respective plateau and gradient case where simple acoustic timescale characterisation may be performed. It is shown that hot spots equivalent with excitation-to-acoustic timescale ratios sufficiently greater than unity exhibit behaviour very similar to a simple plateau-gradient model. Furthermore, for larger hot spots with timescale ratios sufficiently less than unity the reaction behaviour is highly dependent on the smooth temperature profile contained within the core region.« less
Spin morphologies and heat dissipation in spherical assemblies of magnetic nanoparticles
NASA Astrophysics Data System (ADS)
Anand, Manish; Carrey, Julian; Banerjee, Varsha
2016-09-01
Aggregates of magnetic nanoparticles (MNPs) exhibit unusual properties due to the interplay of small system size and long-range dipole-dipole interactions. Using the micromagnetic simulation software oommf, we study the spin morphologies and heat dissipation in micron-size spherical assemblies of MNPs. In particular, we examine the sensitivity of these properties to the dipolar strength, manipulated by the interparticle separation. As oommf is not designed for such a study, we have incorporated a novel scaling protocol for this purpose. We believe that it is essential for all studies where volume fractions are varied. Our main results are as follows: (i) Dense assemblies exhibit strong dipolar effects which yield local magnetic order in the core but not on the surface, where moments are randomly oriented. (ii) The probability distribution of ground-state energy exhibits a long high-energy tail for surface spins in contrast to small tails for the core spins. Consequently, there is a wide variation in the energy of surface spins but not the core spins. (iii) There is strong correlation between ground-state energy and heating properties on application of an oscillating magnetic field h (t ) =hocos2 π f t : the particles in the core heat uniformly, while those on the surface exhibit a wide range from cold to intensely hot. (iv) Specific choices of ho and f yield characteristic spatial heat distributions, e.g., hot surface and cold core, or vice versa. (iv) For all values of ho and f that we consider, heating was maximum at a specific volume fraction. These results are especially relevant in the context of contemporary applications such as hyperthermia and chemotherapy, and also for novel materials such as smart polymer beads and superspin glasses.
NASA Astrophysics Data System (ADS)
Mori, Yoshitaka; Hanayama, Ryohei; Ishii, Katsuhiro; Kitagawa, Yoneyoshi; Sekine, Takashi; Takeuchi, Yasuki; Kurita, Takashi; Katoh, Yoshinori; Satoh, Nakahiro; Kurita, Norio; Kawashima, Toshiyuki; Komeda, Osamu; Hioki, Tatsumi; Motohiro, Tomoyoshi; Sunahara, Atsushi; Sentoku, Yasuhiko; Miura, Eisuke; Iwamoto, Akifumi; Sakagami, Hitoshi
2017-10-01
Fast ignition (FI) is a form of inertial confinement fusion in which the ignition step and the compression step are separate processes resulting in a reduction of the symmetry requirement for hot spot generation. One of the problems of FI so far are the accessibility of an ignition laser pulse into the assembled core in which the driver energy is converted into relativistic electrons produced in the laser-plasma interaction. We have experimentally demonstrated that a tailored-pulse-assembled core with a diameter of 70 μ m, originally a deuterated polystyrene spherical shell of 500 μ m diameter, is flashed by directly counter irradiating 0.8 J/110 fs laser pulses [Y. MORI et al., PRL 2016]. This result indicates that once the assembled core is squeezed into the target center, the heating lasers can access the core's; edges and deposit their energy into the core. In this talk, we will discuss the heating effects in relation to formation of the assembled core.
Slow cooling and highly efficient extraction of hot carriers in colloidal perovskite nanocrystals.
Li, Mingjie; Bhaumik, Saikat; Goh, Teck Wee; Kumar, Muduli Subas; Yantara, Natalia; Grätzel, Michael; Mhaisalkar, Subodh; Mathews, Nripan; Sum, Tze Chien
2017-02-08
Hot-carrier solar cells can overcome the Schottky-Queisser limit by harvesting excess energy from hot carriers. Inorganic semiconductor nanocrystals are considered prime candidates. However, hot-carrier harvesting is compromised by competitive relaxation pathways (for example, intraband Auger process and defects) that overwhelm their phonon bottlenecks. Here we show colloidal halide perovskite nanocrystals transcend these limitations and exhibit around two orders slower hot-carrier cooling times and around four times larger hot-carrier temperatures than their bulk-film counterparts. Under low pump excitation, hot-carrier cooling mediated by a phonon bottleneck is surprisingly slower in smaller nanocrystals (contrasting with conventional nanocrystals). At high pump fluence, Auger heating dominates hot-carrier cooling, which is slower in larger nanocrystals (hitherto unobserved in conventional nanocrystals). Importantly, we demonstrate efficient room temperature hot-electrons extraction (up to ∼83%) by an energy-selective electron acceptor layer within 1 ps from surface-treated perovskite NCs thin films. These insights enable fresh approaches for extremely thin absorber and concentrator-type hot-carrier solar cells.
DOT National Transportation Integrated Search
2009-07-01
Current roadway quality control and quality acceptance (QC/QA) procedures : for Louisiana include coring for thickness, density, and air void checks in hot : mix asphalt (HMA) pavements and thickness and compressive strength for : Portland cement con...
NASA Astrophysics Data System (ADS)
Rivilla, V. M.; Beltrán, M. T.; Martín-Pintado, J.; Fontani, F.; Caselli, P.; Cesaroni, R.
2017-03-01
Context. In recent years, the detection of organic molecules with increasing complexity and potential biological relevance is opening the possibility to understand the formation of the building blocks of life in the interstellar medium. One of the families of molecules of substantial astrobiological interest are the esters. The simplest ester, methyl formate (CH3OCHO), is rather abundant in star-forming regions. The next step in the chemical complexity of esters is ethyl formate, C2H5OCHO. Despite the increase in sensitivity of current telescopes, the detection of complex molecules with more than ten atoms such as C2H5OCHO is still a challenge. Only two detections of this species have been reported so far, which strongly limits our understanding of how complex molecules are formed in the interstellar medium. New detections towards additional sources with a wide range of physical conditions are crucial to differentiate between competing chemical models based on dust grain surface and gas-phase chemistry. Aims: We have searched for ethyl formate towards the W51 e2 hot molecular core, one of the most chemically rich sources in the Galaxy and one of the most promising regions to study prebiotic chemistry, especially after the recent discovery of the P-O bond, key in the formation of DNA. Methods: We have analyzed a spectral line survey towards the W51 e2 hot molecular core, which covers 44 GHz in the 1, 2 and 3 mm bands, carried out with the IRAM 30 m telescope. Results: We report the detection of the trans and gauche conformers of ethyl formate. A local thermodynamic equilibrium analysis indicates that the excitation temperature is 78 ± 10 K and that the two conformers have similar source-averaged column densities of (2.0 ± 0.3) × 10-16 cm-2 and an abundance of 10-8. We compare for the first time the observed molecular abundances of ethyl formate with different competing chemical models based on grain surface and gas-phase chemistry. Conclusions: We propose that grain-surface chemistry may have a dominant role in the formation of ethyl formate (and other complex organic molecules) in hot molecular cores, rather than reactions in the gas phase. Based on observations carried out with the IRAM 30 m Telescope. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).
Development of poloxamer gel formulations via hot-melt extrusion technology.
Mendonsa, Nicole S; Murthy, S Narasimha; Hashemnejad, Seyed Meysam; Kundu, Santanu; Zhang, Feng; Repka, Michael A
2018-02-15
Poloxamer gels are conventionally prepared by the "hot" or the "cold" process. But these techniques have some disadvantages such as high energy consumption, requires expensive equipment and often have scale up issues. Therefore, the objective of this work was to develop poloxamer gels by hot-melt extrusion technology. The model drug selected was ketoprofen. The formulations developed were 30% and 40% poloxamer gels. Of these formulations, the 30% poloxamer gels were selected as ideal gels. DSC and XRD studies showed an amorphous nature of the drug after extrusion. It was observed from the permeation studies that with increasing poloxamer concentration, a decrease in drug permeation was obtained. Other studies conducted for the formulations included in-vitro release studies, texture analysis, rheological studies and pH measurements. In conclusion, the hot-melt extrusion technology could be successfully employed to develop poloxamer gels by overcoming the drawbacks associated with the conventional techniques. Published by Elsevier B.V.
Effect of Heat on Space-Time Correlations in Jets
NASA Technical Reports Server (NTRS)
Bridges, James
2006-01-01
Measurements of space-time correlations of velocity, acquired in jets from acoustic Mach number 0.5 to 1.5 and static temperature ratios up to 2.7 are presented and analyzed. Previous reports of these experiments concentrated on the experimental technique and on validating the data. In the present paper the dataset is analyzed to address the question of how space-time correlations of velocity are different in cold and hot jets. The analysis shows that turbulent kinetic energy intensities, lengthscales, and timescales are impacted by the addition of heat, but by relatively small amounts. This contradicts the models and assumptions of recent aeroacoustic theory trying to predict the noise of hot jets. Once the change in jet potential core length has been factored out, most one- and two-point statistics collapse for all hot and cold jets.
NASA Astrophysics Data System (ADS)
El Diasty, W. Sh.; El Beialy, S. Y.; Anwari, T. A.; Batten, D. J.
2017-06-01
A detailed organic geochemical study of 20 core and cuttings samples collected from the Silurian Tanezzuft Formation, Murzuq Basin, in the south-western part of Libya has demonstrated the advantages of pyrolysis geochemical methods for evaluating the source-rock potential of this geological unit. Rock-Eval pyrolysis results indicate a wide variation in source richness and quality. The basal Hot Shale samples proved to contain abundant immature to early mature kerogen type II/III (oil-gas prone) that had been deposited in a marine environment under terrigenous influence, implying good to excellent source rocks. Strata above the Hot Shale yielded a mixture of terrigenous and marine type III/II kerogen (gas-oil prone) at the same maturity level as the Hot Shale, indicating the presence of only poor to fair source rocks.
Poon, Kean
2017-01-01
Despite significant theoretical advancement in the area of child neuropsychology, limited attention has been paid to the developmental features of adolescence. The present study intends to address this issue in relation to executive function (EF). EF refers to the psychological processes that underlie goal-directed behavior; recent studies separate cool EF (psychological process involves pure logic and critical analysis) and hot EF (psychological process driven by emotion). Although neurological findings suggest that adolescence is a sensitive period for EF development, data on comparing the developmental progression in hot or cool EFs is highly missing. Moreover, while evidence has confirmed the relationships between EF and day-to-day functioning, whether and how hot and cool EFs contribute to core developmental outcomes in adolescence is still remained unknown. The current study aims to enhance our understanding of the development and impacts of hot and cool EFs in adolescence. A total of 136 typically developing adolescents from age 12 to 17 completed four cool EF tasks including Backward digit span, Contingency naming test, Stockings of Cambridge, and Stroop Color and Word test, and one hot task on Cambridge gambling task. Data on academic performance and psychological adjustment was also collected. Results showed that cool and hot EF exhibited different patterns of age-related growth in adolescence. Specifically, cool EF ascended with age while hot EF showed a bell-shaped development. Moreover, there were correlations among cool EF measures but no association between cool and hot EFs. Further, cool EF was a better predictor of academic performance, while hot EF uniquely related to emotional problems. The results provide evidence for the association among cool EF tests and the differentiation of hot and cool EFs. The bell-shaped development of hot EF might suggest a period of heightened risk-taking propensity in middle adolescence. Given the plastic nature of EF, especially over adolescence, the current findings may have practical implications for future EF identification and training.
Poon, Kean
2018-01-01
Despite significant theoretical advancement in the area of child neuropsychology, limited attention has been paid to the developmental features of adolescence. The present study intends to address this issue in relation to executive function (EF). EF refers to the psychological processes that underlie goal-directed behavior; recent studies separate cool EF (psychological process involves pure logic and critical analysis) and hot EF (psychological process driven by emotion). Although neurological findings suggest that adolescence is a sensitive period for EF development, data on comparing the developmental progression in hot or cool EFs is highly missing. Moreover, while evidence has confirmed the relationships between EF and day-to-day functioning, whether and how hot and cool EFs contribute to core developmental outcomes in adolescence is still remained unknown. The current study aims to enhance our understanding of the development and impacts of hot and cool EFs in adolescence. A total of 136 typically developing adolescents from age 12 to 17 completed four cool EF tasks including Backward digit span, Contingency naming test, Stockings of Cambridge, and Stroop Color and Word test, and one hot task on Cambridge gambling task. Data on academic performance and psychological adjustment was also collected. Results showed that cool and hot EF exhibited different patterns of age-related growth in adolescence. Specifically, cool EF ascended with age while hot EF showed a bell-shaped development. Moreover, there were correlations among cool EF measures but no association between cool and hot EFs. Further, cool EF was a better predictor of academic performance, while hot EF uniquely related to emotional problems. The results provide evidence for the association among cool EF tests and the differentiation of hot and cool EFs. The bell-shaped development of hot EF might suggest a period of heightened risk-taking propensity in middle adolescence. Given the plastic nature of EF, especially over adolescence, the current findings may have practical implications for future EF identification and training. PMID:29367850
Detecting Hotspot Information Using Multi-Attribute Based Topic Model
Wang, Jing; Li, Li; Tan, Feng; Zhu, Ying; Feng, Weisi
2015-01-01
Microblogging as a kind of social network has become more and more important in our daily lives. Enormous amounts of information are produced and shared on a daily basis. Detecting hot topics in the mountains of information can help people get to the essential information more quickly. However, due to short and sparse features, a large number of meaningless tweets and other characteristics of microblogs, traditional topic detection methods are often ineffective in detecting hot topics. In this paper, we propose a new topic model named multi-attribute latent dirichlet allocation (MA-LDA), in which the time and hashtag attributes of microblogs are incorporated into LDA model. By introducing time attribute, MA-LDA model can decide whether a word should appear in hot topics or not. Meanwhile, compared with the traditional LDA model, applying hashtag attribute in MA-LDA model gives the core words an artificially high ranking in results meaning the expressiveness of outcomes can be improved. Empirical evaluations on real data sets demonstrate that our method is able to detect hot topics more accurately and efficiently compared with several baselines. Our method provides strong evidence of the importance of the temporal factor in extracting hot topics. PMID:26496635
Lundgren, Karin; Kuklane, Kalev; Venugopal, Vidhya
2014-01-01
Heat stress is a major occupational problem in India that can cause adverse health effects and reduce work productivity. This paper explores this problem and its impacts in selected workplaces, including industrial, service, and agricultural sectors in Chennai, India. Quantitative measurements of heat stress, workload estimations, and clothing testing, and qualitative information on health impacts, productivity loss, etc., were collected. Heat strain and associated impacts on labour productivity between the seasons were assessed using the International Standard ISO 7933:2004, which applies the Predicted Heat Strain (PHS) model. All workplaces surveyed had very high heat exposure in the hot season (Wet Bulb Globe Temperature =29.7), often reaching the international standard safe work values (ISO 7243:1989). Most workers had moderate to high workloads (170-220 W/m2), with some exposed to direct sun. Clothing was found to be problematic, with high insulation values in relation to the heat exposure. Females were found to be more vulnerable because of the extra insulation added from wearing a protective shirt on top of traditional clothing (0.96 clo) while working. When analysing heat strain--in terms of core temperature and dehydration--and associated productivity loss in the PHS model, the parameters showed significant impacts that affected productivity in all workplaces, apart from the laundry facility, especially during the hot season. For example, in the canteen, the core temperature limit of 38°C predicted by the model was reached in only 64 min for women. With the expected increases in temperature due to climate change, additional preventive actions have to be implemented to prevent further productivity losses and adverse health impacts. Overall, this study presented insight into using a thermo-physiological model to estimate productivity loss due to heat exposure in workplaces. This is the first time the PHS model has been used for this purpose. An exploratory approach was taken for further development of the model.
VizieR Online Data Catalog: Rapidly pulsating sdB stars search with GALEX (Boudreaux+, 2017)
NASA Astrophysics Data System (ADS)
Boudreaux, T. M.; Barlow, B. N.; Fleming, S. W.; Soto, A. V.; Million, C.; Reichart, D. E.; Haislip, J. B.; Linder, T. R.; Moore, J. P.
2018-04-01
Here we present a search for short-period hot subdwarf B (sdB) pulsations in the archived GALEX data set using gPhoton (Million+ 2016ApJ...833..292M). An initial sample of 5613 hot subdwarfs (Geier+ 2017, J/A+A/600/A50), which represents a good approximation of all cataloged hot subdwarf stars, was down-selected based on magnitudes, coordinates, and total exposure time available in the gPhoton database, described fully in Section 2. These selection criteria yielded 1881 targets upon which we focused our investigation. Calibrated light curves with time bins of 30s were generated for each target using gPhoton. (4 data files).
Thiolate-Capped CdSe/ZnS Core-Shell Quantum Dots for the Sensitive Detection of Glucose.
Abd Rahman, Samsulida; Ariffin, Nurhayati; Yusof, Nor Azah; Abdullah, Jaafar; Mohammad, Faruq; Ahmad Zubir, Zuhana; Nik Abd Aziz, Nik Mohd Azmi
2017-07-01
A semiconducting water-soluble core-shell quantum dots (QDs) system capped with thiolated ligand was used in this study for the sensitive detection of glucose in aqueous samples. The QDs selected are of CdSe-coated ZnS and were prepared in house based on a hot injection technique. The formation of ZnS shell at the outer surface of CdSe core was made via a specific process namely, SILAR (successive ionic layer adsorption and reaction). The distribution, morphology, and optical characteristics of the prepared core-shell QDs were assessed by transmission electron microscopy (TEM) and spectrofluorescence, respectively. From the analysis, the results show that the mean particle size of prepared QDs is in the range of 10-12 nm and that the optimum emission condition was displayed at 620 nm. Further, the prepared CdSe/ZnS core shell QDs were modified by means of a room temperature ligand-exchange method that involves six organic ligands, L -cysteine, L -histidine, thio-glycolic acid (TGA or mercapto-acetic acid, MAA), mercapto-propionic acid (MPA), mercapto-succinic acid (MSA), and mercapto-undecanoic acid (MUA). This process was chosen in order to maintain a very dense water solubilizing environment around the QDs surface. From the analysis, the results show that the CdSe/ZnS capped with TGA (CdSe/ZnS-TGA) exhibited the strongest fluorescence emission as compared to others; hence, it was tested further for the glucose detection after their treatment with glucose oxidase (GOx) and horseradish peroxidase (HRP) enzymes. Here in this study, the glucose detection is based on the fluorescence quenching effect of the QDs, which is correlated to the oxidative reactions occurred between the conjugated enzymes and glucose. From the analysis of results, it can be inferred that the resultant GOx:HRP/CdSe/ZnS-TGA QDs system can be a suitable platform for the fluorescence-based determination of glucose in the real samples.
Chandra X-Ray Observatory Image of Eta Carinae
NASA Technical Reports Server (NTRS)
1999-01-01
This Chandra X-Ray Observatory image of the mysterious superstar Eta Carinae reveals a surprising hot irner core, creating more questions than answers for astronomers. The image shows three distinct structures: An outer, horseshoe shaped ring about 2 light-years in diameter, a hot inner core about 3 light-months in diameter, and a hot central source less than a light-month in diameter which may contain the superstar. In 1 month, light travels a distance of approximately 489 billion miles (about 788 billion kilometers). All three structures are thought to represent shock waves produced by matter rushing away from the superstar at supersonic speeds. The temperature of the shock-heated gas ranges from 60 million degrees Kelvin in the central regions to 7 million degrees Kelvin on the outer structure. Eta Carinae is one of the most enigmatic and intriguing objects in our galaxy. Between 1837 and 1856, it increased dramatically in brightness to become the most prominent star in the sky except for Sirius, even through it is 7,500 light-years away, more than 80 times the distance to Sirius. This 'Great Eruption,' as it is called, had an energy comparable to a supernova, yet did not destroy the star, which faded to become a dim star, invisible to the naked eye. Since 1940, Eta Carinae has begun to brighten again, becoming visible to the naked eye. Photo credit: NASA/CXC/SAO
NASA Astrophysics Data System (ADS)
Altürk, Bahadır; Konukcu, Fatih
2017-04-01
Agricultural lands that supply food, energy and ecosystem services for human life have been lost due to anthropogenic activities such as construction of roads, urban and industry areas. The significant reasons for the increase of artificial surfaces were poorly planned economic decisions by the government and internal migration due to this poorly planning. Unplanned urban sprawl also give rise to land fragmentation. Fragmentation of agricultural land affects both the agricultural production capacity and rural sustainable employment. In this study: i) Land use changes between 1990-2014 period were assessed using remotely sensed data and ii) Spatial and temporal agricultural land fragmentation were investigated using landscape pattern indice (effective mesh size), Morphological Spatial Pattern Analysis (MSPA) and Entropy method for 25 years period. The selected"hot spot" study area is located on east Thrace region of Turkey, being the service and industrial development zone where agricultural activities, water resources and natural habitat have been damaged due to rapid urban and industrial development for about 25 years. The results showed that agricultural lands decreased 6.44%, urban areas increased 111.68% and industry areas increased 251.19% during this 25 years period. Additionally, fragmentation analyses demonstrated that core agricultural areas sharply decreased and relative fragmentation (effective mesh size) increased from 50.68% to 56.77% during 1990 and 2014.
Ma, T.; Chen, H.; Patel, P. K.; ...
2016-08-18
The electron temperature at stagnation of an ICF implosion can be measured from the emission spectrum of high-energy x-rays that pass through the cold material surrounding the hot stagnating core. We describe a platform developed on the National Ignition Facility where trace levels of a mid-Z dopant (krypton) are added to the fuel gas of a symcap (symmetry surrogate) implosion to allow for the use of x-ray spectroscopy of the krypton line emission.Published by AIP Publishing
Ma, T; Chen, H; Patel, P K; Schneider, M B; Barrios, M A; Casey, D T; Chung, H-K; Hammel, B A; Berzak Hopkins, L F; Jarrott, L C; Khan, S F; Lahmann, B; Nora, R; Rosenberg, M J; Pak, A; Regan, S P; Scott, H A; Sio, H; Spears, B K; Weber, C R
2016-11-01
The electron temperature at stagnation of an ICF implosion can be measured from the emission spectrum of high-energy x-rays that pass through the cold material surrounding the hot stagnating core. Here we describe a platform developed on the National Ignition Facility where trace levels of a mid-Z dopant (krypton) are added to the fuel gas of a symcap (symmetry surrogate) implosion to allow for the use of x-ray spectroscopy of the krypton line emission.
Proceedings of the NSW Thermal Workshop, Held in Virginia Beach, Virginia on 16-17 September 1991
1992-09-01
average of only 1.2 ’C over the 4- and 6-hour trials. HOT/DRY STRESS PHYSIOLOGICAL RESPONSES Heat stroke: we see a rapid rise in core temperature to...protective measurement? And yet, my data will show an average low core temperature for all the "guys." Say these two guys are average or got to 350 C. 125...nations. LARRY W. LAUGHLIN CAPT, MC, USN Commanding Officer Naval Medical Research institute SJUpl’rtfV StIICAICION Oi iMi PACA REPORT DOCUMENTATION
NASA Astrophysics Data System (ADS)
Ma, T.; Chen, H.; Patel, P. K.; Schneider, M. B.; Barrios, M. A.; Casey, D. T.; Chung, H.-K.; Hammel, B. A.; Berzak Hopkins, L. F.; Jarrott, L. C.; Khan, S. F.; Lahmann, B.; Nora, R.; Rosenberg, M. J.; Pak, A.; Regan, S. P.; Scott, H. A.; Sio, H.; Spears, B. K.; Weber, C. R.
2016-11-01
The electron temperature at stagnation of an ICF implosion can be measured from the emission spectrum of high-energy x-rays that pass through the cold material surrounding the hot stagnating core. Here we describe a platform developed on the National Ignition Facility where trace levels of a mid-Z dopant (krypton) are added to the fuel gas of a symcap (symmetry surrogate) implosion to allow for the use of x-ray spectroscopy of the krypton line emission.
Hot subluminous stars: On the Search for Chemical Signatures of their Genesis
NASA Astrophysics Data System (ADS)
Hirsch, Heiko Andreas
2009-10-01
This thesis deals with the hot subluminous stars of spectral class O. Although the name suggests otherwise, these stars are still 10 to 1000 times more luminous than the sun, they emit most of their radiation energy in the ultraviolet range. First stars of this type have been categorized in the 1950ies. Since they are blue objects like Quasars they often are discovered in surveys at high Galactic latitudes aiming at Quasars and other extragalactic objects. The hot subluminous stars can be divided into two classes, the subluminous O and subluminous B stars, or short sdO and sdB. The sdOs and sdBs play an important role in astronomy, as many old stellar populations, e.g. globular clusters and elliptical galaxies, have strong UV fluxes. UV bright regions often are "stellar nurseries", where new stars are born. Globular clusters and elliptical galaxies, however, do not experience star formation. This UV excess can be explained by population models that include the hot subluminous stars. Many sdB stars show short-period, multiperiodic light variations, which are due to radial and nonradial pulsations. Asteroseismology can explore the inner structure of stars and estimate e.g. the stellar mass, a variable that can only determine in very lucky circumstances (eclipsing binaries). These stars are also important for cosmology because they qualify as supernova Ia progenitors. The nature of the sdO stars is less well understood than that of their cooler and more numerous siblings, the sdBs. The connection of the sdBs to the horizontal branch is established for many years now, accordingly they are old helium core burning objects after their red giant phase. More precisely, they are on the extended horizontal branch (EHB), the hot end of the horizontal branch. EHB stars are characterized by a very low envelope mass, i.e. we see more or less directly the hot helium burning core. Strong mass loss in the RGB phase is regarded as responsible for this phenomenon, the exact mechanism, however, is still under debate. While the cooler sdBs can be analyzed with relatively simple LTE model atmospheres, the hot sdOs require much more sophisticated NLTE calculations. The large effort required for sdO analyses resulted in a relatively low number of paper on the subject, when compared with the numerous publications on sdB stars. Besides a few detailed studies of individuell objects, the ≈ 50 stars analyzed by Ströer et al. (2007) is the only extensive work on sdOs. They explained the helium poor sdOs as progeny of the sdB stars. But for the helium enriched sdOs, no definite statement about their evolutionary status could be found. In order to get a large sample of sdOs, this work made use of the Sloan Digital Sky Survey (SDSS), one of the most extensive photometric and spectroscopic surveys in astronomy. About 14000 spectra were classified by visual inspection by means of easily recognizable spectral features. We now have a large database with classificatons of hot stars. The majority of the spectra were classified as white dwarfs, among them a number of previously unknown magnetic white dwarfs. 1500 objects were identified as hot subluminous stars, about 200 of them are sdOs. We determined effective temperatures, surface gravities and atmospheric helium abundances for these objects. Two evolutionary scenarios remain valid options for the sdOs' origin: The merging of two helium white dwarfs and the delayed helium flash of a red giant star ("late hot flasher"). In the first scenario, two low mass white dwarfs in short period orbits lose orbital energy by radiation of gravitational waves. As their orbit shrinks, the less massive one will fill its Roche lobe and get disrupted and accreted on the companion. Unfortunately no detailed calculations of the explosive nucleosynthesis exist for this scenario. The late hot flashers are stars that do not experience the helium core flash until they leave their red giant phase and already evolve towards the white dwarfs. Miller Bertolami et al. (2008) published detailed theoretical calculations for this scenario. They predict a strong enrichment with carbon and in some cases with nitrogen by mixing processes. A differentiation between both scenarios was not possible so far, as we only determined helium abundances. The creation of new NLTE model atmospheres which include carbon and nitrogen enabled us to measure their abundances in three dozen sdOs. Effective temperatures did not change much with the application of the new models, but the surface gravity was found about 0.2 dex lower than in previous analyses. This provides a solution for a handful of stars that until now were situated below the helium main sequence, which would not allow stable helium core burning. On the other hand, the whole distribution is shifted towards lower gravities while the theoretical calculations predict an accumulation of stars at higher surface gravities, near the helium main sequence. The measured carbon abundances reveal a bimodal distribution: half of the objects has carbon enriched up to 10 times the solar value, a clear indication of 3α processed material mixed from the core into the envelope, the other half shows carbon strongly depleted. With some exceptions, nitrogen is above solar abundances, up to a factor of ten. Stars with very low carbon content cannot have experienced mixing of matter from the core into the envelope, only CNO-processed matter is exposed. Three stars with high carbon abundances are found that have a very low nitrogen content. These stars are not easily understood: matter from the core must have been brought into the envelope, but not the CNO-processed matter. A surprising correlation is found for the rotational velocites with abundances: nearly all stars with high carbon abundances also have high projected rotational velocities vrot sin i = 10 . . . 30 km s-1. Because the sdB stars are very slow rotating with vrot sin i < 10 km s-1 (unless spun up by tidal iteraction in close binary systems), this disqualifies any evolutionary connection between sdBs and the carbon rich sdOs. Those stars without carbon on the other hand show no significant rotational broadening in their line profiles. Altogether eight stars can be considered as compatible with having experienced a delayed helium flash. Those stars with high nitrogen abundances but only very little atmospheric carbon are not predicted by any late hot flasher calculation. They are considered candidates for the white dwarf merging scenario, which we cannot yet verify due to missing calculations. Another remaining problem are the three stars with high carbon, but very low nitrogen abundances. One possible explanation would be a very metal poor (halo) origin for these objects, which could be verified in the future by a quantitative analysis of the heavier metals. Alternatively the examinations of the kinematic properties of the stars could provide clues concerning their membership to the halo population.
Selection of a turbine cooling system applying multi-disciplinary design considerations.
Glezer, B
2001-05-01
The presented paper describes a multi-disciplinary cooling selection approach applied to major gas turbine engine hot section components, including turbine nozzles, blades, discs, combustors and support structures, which maintain blade tip clearances. The paper demonstrates benefits of close interaction between participating disciplines starting from early phases of the hot section development. The approach targets advancements in engine performance and cost by optimizing the design process, often requiring compromises within individual disciplines.
Ping, Wong Chee; Keong, Chen Chee; Bandyopadhyay, Amit
2010-07-01
Athletes in Malaysia need to perform in a hot and humid climate. Chronic supplementation of caffeine on endurance performance have been studied extensively in different populations. However, concurrent research on the effects of acute supplementation of caffeine on cardiorespiratory responses during endurance exercise in the Malaysian context especially in a hot and humid environment is unavailable. Nine heat adapted recreational Malaysian male runners (aged: 25.4+/-6.9 yr) who were nonusers of caffeine (23.7+/-12.6 mg per day) were recruited in this placebo--controlled double--blind randomized study. Caffeine (5 mg per kg of body weight) or placebo was ingested in the form of a capsule one hour prior to the running exercise trial at 70 per cent of VO2max on a motorised treadmill in a heat-controlled laboratory (31 degrees C, 70% relative humidity). Subjects drank 3 ml of cool water per kg of body weight every 20 min during the running trials to avoid the adverse effects of dehydration. Heart rate, core body temperature and rate of perceived exertion (RPE) were recorded at intervals of 10 min, while oxygen consumption was measured at intervals of 20 min. Running time to exhaustion was significantly (P<0.05) higher in the caffeine trial compared to the placebo trial. Heart rate, core body temperature, oxygen uptake and RPE did not show any significant variation between the trials but it increased significantly during exercise from their respective resting values in both trials (P<0.001). Our study showed that ingestion of 5 mg of caffeine per kg of body weight improved the endurance running performance but did not impose any significant effect on other individual cardiorespiratory parameters of heat-acclimated recreational runners in hot and humid conditions.
TIDALLY DRIVEN ROCHE-LOBE OVERFLOW OF HOT JUPITERS WITH MESA
DOE Office of Scientific and Technical Information (OSTI.GOV)
Valsecchi, Francesca; Rasio, Frederic A.; Rappaport, Saul
2015-11-10
Many exoplanets have now been detected in orbits with ultra-short periods very close to the Roche limit. Building upon our previous work, we study the possibility that mass loss through Roche lobe overflow (RLO) may affect the evolution of these planets, and could possibly transform a hot Jupiter into a lower-mass planet (hot Neptune or super-Earth). We focus here on systems in which the mass loss occurs slowly (“stable mass transfer” in the language of binary star evolution) and we compute their evolution in detail with the binary evolution code Modules for Experiments in Stellar Astrophysics. We include the effectsmore » of tides, RLO, irradiation, and photo-evaporation (PE) of the planet, as well as the stellar wind and magnetic braking. Our calculations all start with a hot Jupiter close to its Roche limit, in orbit around a Sun-like star. The initial orbital decay and onset of RLO are driven by tidal dissipation in the star. We confirm that such a system can indeed evolve to produce lower-mass planets in orbits of a few days. The RLO phase eventually ends and, depending on the details of the mass transfer and on the planetary core mass, the orbital period can remain around a few days for several Gyr. The remnant planets have rocky cores and some amount of envelope material, which is slowly removed via PE at a nearly constant orbital period; these have properties resembling many of the observed super-Earths and sub-Neptunes. For these remnant planets, we also predict an anti-correlation between mass and orbital period; very low-mass planets (M{sub pl} ≲ 5 M{sub ⊕}) in ultra-short periods (P{sub orb} < 1 day) cannot be produced through this type of evolution.« less
The crime prevention value of hot spots policing.
Braga, Anthony A
2006-08-01
This paper reviews the available research evidence on the effectiveness of hot spots policing programs in reducing crime and disorder. The research identified five randomized controlled experiments and four non-equivalent control group quasi-experiments evaluating the effects of hot spots policing interventions on crime. Seven of nine selected evaluations reported noteworthy crime and disorder reductions. Meta-analyses of the randomized experiments revealed statistically significant mean effect sizes favoring hot spots policing interventions in reducing citizen calls for service in treatment places relative to control places. When immediate spatial displacement was measured, it was very limited and unintended crime prevention benefits were associated with the hot spots policing programs. The results of this review suggest that hot spots policing is an effective crime prevention strategy.
Evaluation of hot in-place recycle.
DOT National Transportation Integrated Search
2010-06-01
This report documents the construction of hot in-place recycled (HIPR) pavement on SR 542. : HIPR is a process by which rehabilitation of the existing HMA pavement occurs on site in one : operation. HIPR project selection, mix design, construction an...
The Role of “Vortical” Hot Towers in the Formation of Tropical Cyclone Diana (1984).
NASA Astrophysics Data System (ADS)
Hendricks, Eric A.; Montgomery, Michael T.; Davis, Christopher A.
2004-06-01
A high-resolution (3-km horizontal grid spacing) near-cloud-resolving numerical simulation of the formation of Hurricane Diana (1984) is used to examine the contribution of deep convective processes to tropical cyclone formation. This study is focused on the 3-km horizontal grid spacing simulation because this simulation was previously found to furnish an accurate forecast of the later stages of the observed storm life cycle. The numerical simulation reveals the presence of vortical hot towers, or cores of deep cumulonimbus convection possessing strong vertical vorticity, that arise from buoyancy-induced stretching of local absolute vertical vorticity in a vorticity-rich prehurricane environment.At near-cloud-resolving scales, these vortical hot towers are the preferred mode of convection. They are demonstrated to be the most important influence to the formation of the tropical storm via a two-stage evolutionary process: (i) preconditioning of the local environment via diabatic production of multiple small-scale lower-tropospheric cyclonic potential vorticity (PV) anomalies, and (ii) multiple mergers and axisymmetrization of these low-level PV anomalies. The local warm-core formation and tangential momentum spinup are shown to be dominated by the organizational process of the diabatically generated PV anomalies; the former process being accomplished by the strong vertical vorticity in the hot tower cores, which effectively traps the latent heat from moist convection. In addition to the organizational process of the PV anomalies, the cyclogenesis is enhanced by the aggregate diabatic heating associated with the vortical hot towers, which produces a net influx of low-level mean angular momentum throughout the genesis.Simpler models are examined to elucidate the underlying dynamics of tropical cyclogenesis in this case study. Using the Sawyer Eliassen balanced vortex model to diagnose the macroscale evolution, the cyclogenesis of Diana is demonstrated to proceed in approximate gradient and hydrostatic balance at many instances, where local radial and vertical accelerations are small. Using a shallow water primitive equation model, a characteristic “moist” (diabatic) vortex merger in the cloud-resolving numerical simulation is captured in a large part by the barotropic model. Since a moist merger results in a stronger vortex and occurs twice as fast as a dry merger, it is inferred (consistent with related work) that a net low-level convergence can accelerate and intensify the merger process in the real atmosphere.Although the findings reported herein are based on a sole case study and thus cannot yet be generalized, it is believed the results are sufficiently interesting to warrant further idealized simulations of this nature.
In-place voids monitoring of hot mix asphalt pavements : follow-up.
DOT National Transportation Integrated Search
2014-01-01
In order to validate the policy of allowing the adjustment of the asphalt cement to reduce the laboratory : air voids up to one percent, cores were taken over a period of four years on 19 paving projects and : tested for air voids. After being compac...
The Unrelenting Search for a Quick Fix
ERIC Educational Resources Information Center
Marinak, Barbara A.
2016-01-01
Cassidy, Ortlieb, and Grote-Garcia (2016) have penned an important and insightful article. This reflection on the impact of the Common Core State Standards (CCSS; National Governors Association [NGA] Center for Best Practices & Council of Chief State School Officers [CCSSO], 2010) through the lens of "What's Hot, What's Not" for two…
DOT National Transportation Integrated Search
2000-10-01
This report reviews Manitoba's and Minnesota's Specific Pavement Studies (SPS-5) projects. The studies focus on investigating the performance of hot mix asphalt (HMA) overlays on HMA pavements and involve nine core test sections. The SPS-5 design var...
Primary atomization of liquid jets issuing from rocket engine coaxial injectors
NASA Astrophysics Data System (ADS)
Woodward, Roger D.
1993-01-01
The investigation of liquid jet breakup and spray development is critical to the understanding of combustion phenomena in liquid-propellant rocket engines. Much work has been done to characterize low-speed liquid jet breakup and dilute sprays, but atomizing jets and dense sprays have yielded few quantitative measurements due to their optical opacity. This work focuses on a characteristic of the primary breakup process of round liquid jets, namely the length of the intact liquid core. The specific application considered is that of shear-coaxial type rocket engine injectors. Real-time x-ray radiography, capable of imaging through the dense two-phase region surrounding the liquid core, has been used to make the measurements. Nitrogen and helium were employed as the fuel simulants while an x-ray absorbing potassium iodide aqueous solution was used as the liquid oxygen (LOX) simulant. The intact-liquid-core length data have been obtained and interpreted to illustrate the effects of chamber pressure (gas density), injected-gas and liquid velocities, and cavitation. The results clearly show that the effect of cavitation must be considered at low chamber pressures since it can be the dominant breakup mechanism. A correlation of intact core length in terms of gas-to-liquid density ratio, liquid jet Reynolds number, and Weber number is suggested. The gas-to-liquid density ratio appears to be the key parameter for aerodynamic shear breakup in this study. A small number of hot-fire, LOX/hydrogen tests were also conducted to attempt intact-LOX-core measurements under realistic conditions in a single-coaxial-element rocket engine. The tests were not successful in terms of measuring the intact core, but instantaneous imaging of LOX jets suggests that LOX jet breakup is qualitatively similar to that of cold-flow, propellant-simulant jets. The liquid oxygen jets survived in the hot-fire environment much longer than expected, and LOX was even visualized exiting the chamber nozzle under some conditions. This may be an effect of the single element configuration.
Wang, Qing; Qiu, Jingwen; Li, Yang; Shen, Fei
2015-10-01
In order to explore the possibility of Jerusalem artichoke stalk for bioenergy conversion, we analyzed the main composition of whole stalk, pitch, and core of the stalk. Meanwhile, these parts were pretreated with different NaOH concentrations at 121 degrees C. Afterwards, enzymatic hydrolysis was performed to evaluate the pretreatment efficiency. Jerusalem artichoke stalk was characterized by relatively high lignin content (32.0%) compared with traditional crop stalks. The total carbohydrate content was close to that of crop stalks, but with higher cellulose content (40.5%) and lower hemicellulose (19.6%) than those of traditional crop stalks. After pretreatment, the lignin content in the whole stalk, pitch, and core decreased by 13.1%-13.4%, 8.3%-13.5%, and 19.9%-27.2%, respectively, compared with the unpretreated substrates. The hemicellulose content in the whole stalk, pitch, and core decreased 87.8%-96.9%, 87.6%-95.0%, and 74.0%-90.2%, respectively. Correspondingly, the cellulose content in the pretreated whole stalk, pitch, and core increased by 56.5%-60.2%, 52.2%-55.4%, and 62.7%-73.2%, respectively. Moreover, increase of NaOH concentration for pretreatment could improve the enzymatic hydrolysis of the whole stalk and pitch by 2.3-2.6 folds and 10.3-18.5 folds, respectively. The hydrolysis of pretreated stalk core decreased significantly as 2.0 mol/L NaOH was employed, although the increased NaOH concentration can also improve its hydrolysis performance. Based on these results, hot-NaOH can be regarded as an option for Jerusalem artichoke stalk pretreatment. Increasing NaOH concentration was beneficial to hemicellulose and lignin removal, and consequently improved sugar conversion. However, the potential decrease of sugar conversion of the pretreated core by higher NaOH concentration suggested further optimization on the pretreatment conditions should be performed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Qin, Sheng-Li; Schilke, Peter; Sánchez-Monge, Álvaro
2015-04-10
We report on the Submillimeter Array (SMA) observations of molecular lines at 270 GHz toward the W3(OH) and W3(H{sub 2}O) complex. Although previous observations already resolved the W3(H{sub 2}O) into two or three sub-components, the physical and chemical properties of the two sources are not well constrained. Our SMA observations clearly resolved the W3(OH) and W3(H{sub 2}O) continuum cores. Taking advantage of the line fitting tool XCLASS, we identified and modeled a rich molecular spectrum in this complex, including multiple CH{sub 3}CN and CH{sub 3}OH transitions in both cores. HDO, C{sub 2}H{sub 5}CN, O{sup 13}CS, and vibrationally excited lines ofmore » HCN, CH{sub 3}CN, and CH{sub 3}OCHO were only detected in W3(H{sub 2}O). We calculate gas temperatures and column densities for both cores. The results show that W3(H{sub 2}O) has higher gas temperatures and larger column densities than W3(OH) as previously observed, suggesting physical and chemical differences between the two cores. We compare the molecular abundances in W3(H{sub 2}O) to those in the Sgr B2(N) hot core, the Orion KL hot core, and the Orion Compact Ridge, and discuss the chemical origin of specific species. An east–west velocity gradient is seen in W3(H{sub 2}O), and the extension is consistent with the bipolar outflow orientation traced by water masers and radio jets. A north–south velocity gradient across W3(OH) is also observed. However, with current observations we cannot be assured whether the velocity gradients are caused by rotation, outflow, or radial velocity differences of the sub-components of W3(OH)« less
Chandra Discovers Elusive "Hot Bubble" in Planetary Nebula
NASA Astrophysics Data System (ADS)
2000-06-01
NASA's Chandra X-ray Observatory has imaged for the first time a "hot bubble" of gas surrounding a dying, Sun-like star. This large region of very hot gas in the planetary nebula BD+30 3639 has a peculiar shape and contains elements produced in the core of the dying star. "The new Chandra image offers conclusive proof for the existence of the "hot bubble" that theorists have long predicted," said Professor Joel Kastner, of the Chester F. Carlson Center of Imaging Science at the Rochester Institute of Technology. Kastner leads a team of scientists who reported on this observation at the 196th national meeting of the American Astronomical Society in Rochester, New York. The Chandra image shows a region of 3 million degree Celsius gas that appears to fit inside the shell of ionized gas seen by the Hubble Space Telescope. The optical and X-ray emitting regions of BD+30 3639, which lies between 5000 and 8000 light years away, are roughly one million times the volume of our solar system. A planetary nebula (so called because it looks like a planet when viewed with a small telescope) is formed when a dying red giant star puffs off its outer layer, leaving behind a hot core that will eventually collapse to form a dense star called a white dwarf. According to theory, a "hot bubble" is formed when a new, two million mile per hour wind emanating from the hot core rams into the ejected atmosphere, producing energetic shocks and heating the interaction region to temperatures of millions of degrees. Previous X-ray observations hinted that X rays might be coming from a region larger than the central star but it remained for Chandra to provide definite proof. The shape of the X-ray emission was a surprise to the researchers. "This suggests that the red giant atmosphere was not ejected symmetrically,"said Kastner. "It might be pointing to an unseen companion star," The spectrum shows a large abundance of neon in the X-ray-emitting gas. This indicates that gas contained in the hot bubble gas was dredged up from the deepest layers of the central star, where nuclear fusion altered the chemical composition of the gas prior to its being ejected. Thus the Chandra data may offer new insight into the process whereby dying stars enrich the Milky Way in fusion products. The observation was made in March 2000 using the Advanced CCD Imaging Spectrometer (ACIS). Kastner's collaborators on the project are Prof. Noam Soker of the University of Haifa, Israel; Prof. Saul Rappaport of MIT; Dr. Ruth Knill-Dgani of the University of Texas, Austin; and Dr. Saeqa Vrtilek of the Harvard-Smithsonian Center for Astrophysics. The ACIS instrument was built for NASA by the Massachusetts Institute of Technology, Cambridge, and Pennsylvania State University, University Park. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program. TRW, Inc., Redondo Beach, Calif., is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass. High resolution digital versions of the X-ray image (JPG, 300 dpi TIFF ) and other information associated with this release are available on the Internet at: http://chandra.harvard.edu AND http://chandra.nasa.gov
A cost-comparison methodology for selecting appropriate hot-mix asphalt materials.
DOT National Transportation Integrated Search
2007-01-01
The Virginia Department of Transportation's (VDOT) Road and Bridge Specifications lists 9 dense-graded hot-mix asphalt (HMA) surface mixes (three aggregate gradations x three binder types) that could be used on Virginia's highways. VDOT's Special Pro...
Use of roadway attributes in hot spot identification and analysis.
DOT National Transportation Integrated Search
2015-10-01
This research focuses on the addition of roadway attributes in the selection and analysis of hot spots. This : is in conjunction with the framework for highway safety mitigation in Utah with its six primary steps: network : screening, diagnosis...
Enose, Arno A.; Dasan, Priya K.; Sivaramakrishnan, H.; Shah, Sanket M.
2014-01-01
Solid dispersion is molecular dispersion of drug in a polymer matrix which leads to improved solubility and hence better bioavailability. Solvent evaporation technique was employed to prepare films of different combinations of polymers, plasticizer, and a modal drug sulindac to narrow down on a few polymer-plasticizer-sulindac combinations. The sulindac-polymer-plasticizer combination that was stable with good film forming properties was processed by hot melt mixing, a technique close to hot melt extrusion, to predict its behavior in a hot melt extrusion process. Hot melt mixing is not a substitute to hot melt extrusion but is an aid in predicting the formation of molecularly dispersed form of a given set of drug-polymer-plasticizer combination in a hot melt extrusion process. The formulations were characterized by advanced techniques like optical microscopy, differential scanning calorimetry, hot stage microscopy, dynamic vapor sorption, and X-ray diffraction. Subsequently, the best drug-polymer-plasticizer combination obtained by hot melt mixing was subjected to hot melt extrusion process to validate the usefulness of hot melt mixing as a predictive tool in hot melt extrusion process. PMID:26556187
The NASA thermionic-conversion (TEC-ART) program
NASA Technical Reports Server (NTRS)
Morris, J. F.
1977-01-01
The current emphasis is on out-of-core thermionic conversion (TEC). The additional degrees of freedom offer new potentialities, but high-temperature material effects determine the level and lifetime of TEC performance: New electrodes not only raise power outputs but also maintain them regardless of emitter-vapor deposition on collectors. In addition, effective electrodes serve compatibly with hot-shell alloys. Space TEC withstands external and internal high-temperature vaporization problems, and terrestrial TEC tolerates hot corrosive atmospheres outside and near-vacuum inside. Finally, reduction of losses between converter electrodes is essential even though rather demanding geometries appear to be required for some modes of enhanced operation.
Nonvalidity of I-Love-Q Relations for Hot White Dwarf Stars
NASA Astrophysics Data System (ADS)
Boshkayev, K.; Quevedo, H.
2018-05-01
The equilibrium configurations of uniformly rotating white dwarfs at finite temperatures are investigated, exploiting the Chandrasekhar equation of state for different isothermal cores. The Hartle-Thorne formalism is applied to construct white dwarf configurations in the framework of Newtonian physics. The equations of structure are considered in the slow rotation approximation and all basic parameters of rotating hot white dwarfs are computed to test the so-called moment of inertia, tidal Love number and quadrupole moment (I-Love-Q) relations. It is shown that even within the same equation of state the I-Love-Q relations are not universal for white dwarfs at finite temperatures.
Arc-Heater Facility for Hot Hydrogen Exposure of Nuclear Thermal Rocket Materials
NASA Technical Reports Server (NTRS)
Litchford, Ron J.; Foote, John P.; Wang,Ten-See; Hickman, Robert; Panda, Binayak; Dobson, Chris; Osborne, Robin; Clifton, Scooter
2006-01-01
A hyper-thermal environment simulator is described for hot hydrogen exposure of nuclear thermal rocket material specimens and component development. This newly established testing capability uses a high-power, multi-gas, segmented arc-heater to produce high-temperature pressurized hydrogen flows representative of practical reactor core environments and is intended to serve. as a low cost test facility for the purpose of investigating and characterizing candidate fueUstructura1 materials and improving associated processing/fabrication techniques. Design and development efforts are thoroughly summarized, including thermal hydraulics analysis and simulation results, and facility operating characteristics are reported, as determined from a series of baseline performance mapping tests.
Miyazawa, Taiki; Kawabata, Takashi; Okazaki, Kazunobu; Suzuki, Takashi; Imai, Daiki; Hamamoto, Takeshi; Matsumura, Shinya; Miyagawa, Toshiaki
2012-02-29
Central administration of γ-amino butyric acid (GABA) induces lower body temperature in animals in hot ambient air. However, it is still unknown whether oral GABA administration affects temperature regulation at rest in a hot environment in humans. Therefore, in the present study, we specifically hypothesized that systemic administration of GABA in humans would induce hypothermia in a hot environment and that this response would be observed in association with decreased heat production. Eight male participants drank a 200-ml sports drink with 1 g of GABA (trial G) or without GABA (trial C), then rested for 30 minutes in a sitting position in a hot environment (ambient air temperature 33°C, relative humidity 50%). We found that changes in esophageal temperature from before drinking the sports drink were lower in trial G than in trial C (-0.046 ± 0.079°C vs 0.001 ± 0.063°C; P < 0.05), with lower heat production calculated by oxygen consumption (41 ± 5 W/m2 vs 47 ± 8 W/m2; P < 0.05). In this study, we have demonstrated that a single oral administration of GABA induced a larger decrease in body core temperature compared to a control condition during rest in a hot environment and that this response was concomitant with a decrease in total heat production.
Slow cooling and highly efficient extraction of hot carriers in colloidal perovskite nanocrystals
Li, Mingjie; Bhaumik, Saikat; Goh, Teck Wee; Kumar, Muduli Subas; Yantara, Natalia; Grätzel, Michael; Mhaisalkar, Subodh; Mathews, Nripan; Sum, Tze Chien
2017-01-01
Hot-carrier solar cells can overcome the Shockley-Queisser limit by harvesting excess energy from hot carriers. Inorganic semiconductor nanocrystals are considered prime candidates. However, hot-carrier harvesting is compromised by competitive relaxation pathways (for example, intraband Auger process and defects) that overwhelm their phonon bottlenecks. Here we show colloidal halide perovskite nanocrystals transcend these limitations and exhibit around two orders slower hot-carrier cooling times and around four times larger hot-carrier temperatures than their bulk-film counterparts. Under low pump excitation, hot-carrier cooling mediated by a phonon bottleneck is surprisingly slower in smaller nanocrystals (contrasting with conventional nanocrystals). At high pump fluence, Auger heating dominates hot-carrier cooling, which is slower in larger nanocrystals (hitherto unobserved in conventional nanocrystals). Importantly, we demonstrate efficient room temperature hot-electrons extraction (up to ∼83%) by an energy-selective electron acceptor layer within 1 ps from surface-treated perovskite NCs thin films. These insights enable fresh approaches for extremely thin absorber and concentrator-type hot-carrier solar cells. PMID:28176882
NASA Technical Reports Server (NTRS)
Nakazawa, S.
1988-01-01
This annual status report presents the results of work performed during the fourth year of the 3-D Inelastic Analysis Methods for Hot Section Components program (NASA Contract NAS3-23697). The objective of the program is to produce a series of new computer codes permitting more accurate and efficient 3-D analysis of selected hot section components, i.e., combustor liners, turbine blades and turbine vanes. The computer codes embody a progression of math models and are streamlined to take advantage of geometrical features, loading conditions, and forms of material response that distinguish each group of selected components. Volume 1 of this report discusses the special finite element models developed during the fourth year of the contract.
Summary of the thermal evaluation of LWBR (LWBR Development Program)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lerner, S.; McWilliams, K.D.; Stout, J.W.
1980-03-01
This report describes the thermal evaluation of the core for the Shippingport Light Water Breeder Reactor. This core contains unique thermal-hydraulic features such as (1) close rod-to-rod proximity, (2) an open-lattice array of fuel rods with two different diameters and rod-to-rod spacings in the same flow region, (3) triplate orifices located at both the entrance and exit of fuel modules and (4) a hydraulically-balanced movable-fuel system coupled with (5) axial-and-radial fuel zoning for reactivity control. Performance studies used reactor thermal principles such as the hot-and-nominal channel concept and related nuclear/engineering design allowances. These were applied to models of three-dimensional roddedmore » arrays comprising the core fuel regions.« less
Beyond the Core: The Hot Topic(al) Alternative to the Survey-Based Introduction to Sociology Course.
Schwartz, Michael; Smith, R Tyson
2010-10-01
In the following paper we argue that the conventional "Introduction to Sociology" survey course should be restructured because such courses try to survey an unsurveyable body of knowledge and they do not teach the application of sociological research. The conventional intro course should be replaced with an intro course that surveys the types of social dynamics that sociologists typically research and the methods they use to do so. We propose a semester-long intro course with four case study learning-units that are chosen for their coverage of the underlying sociological dynamics, methods, and core concepts. We contend that case study learning-units which concentrate on topical issues and core sociological concepts are better suited for an introduction course.
A ventilation cooling shirt worn during office work in a hot climate: cool or not?
Zhao, Mengmeng; Kuklane, Kalev; Lundgren, Karin; Gao, Chuansi; Wang, Faming
2015-01-01
The aim of the study was to identify whether a ventilation cooling shirt was effective in reducing heat strain in a hot climate. Eight female volunteers were exposed to heat (38 °C, 45% relative humidity) for 2 h with simulated office work. In the first hour they were in normal summer clothes (total thermal insulation 0.8 clo); in the second hour a ventilation cooling shirt was worn on top. After the shirt was introduced for 1 h, the skin temperatures at the scapula and the chest were significantly reduced (p < 0.05). The mean skin and core temperatures were not reduced. The subjects felt cooler and more comfortable by wearing the shirt, but the cooling effect was most conspicuous only during the initial 10 min. The cooling efficiency of the ventilation shirt was not very effective under the low physical activity in this hot climate.
Morphology of a Hot Coronal Cavity Core as Observed by Hinode/XRT
NASA Technical Reports Server (NTRS)
Reeves, K. K.; Gibson, S. E.; Kucera, T. A.; Hudson, H. S.
2010-01-01
We follow a coronal cavity that was observed by Hinode/XRT during the summer of 2008. This cavity has a persistent area of relatively bright X-ray emission in its center. We use multifilter data from XRT to study the thermal emission from this cavity, and find that the bright center is hotter than the surrounding cavity plasma with temperatures of about 1.6 MK. We follow the morphology of this hot feature as the cavity structure rotates over the limb during the several days between July 19 - 23 2008. We find that the hot structure at first looks fairly circular, then appears to expand and elongate, and then shrinks again to a compact circular shape. We interpret this apparent change in shape as being due to the morphology of the filament channel associated with the cavity, and the change in viewing angle as the structure rotates over the limb of the Sun.
Long-term performance of a hot in-place recycling project final report.
DOT National Transportation Integrated Search
2016-08-01
This report documents the construction and long-term performance of a hot in-place recycled (HIPR) : project on SR 542. HIPR project selection, mix design, construction and testing are described. It was shown that : the HIPR process successfully reha...
NASA Astrophysics Data System (ADS)
Heber, U.
2016-08-01
Hot subluminous stars of spectral type B and O are core helium-burning stars at the blue end of the horizontal branch or have evolved even beyond that stage. Most hot subdwarf stars are chemically highly peculiar and provide a laboratory to study diffusion processes that cause these anomalies. The most obvious anomaly lies with helium, which may be a trace element in the atmosphere of some stars (sdB, sdO) while it may be the dominant species in others (He-sdB, He-sdO). Strikingly, the distribution in the Hertzsprung-Russell diagram of He-rich versus He-poor hot subdwarf stars of the globular clusters ω Cen and NGC 2808 differ from that of their field counterparts. The metal-abundance patterns of hot subdwarfs are typically characterized by strong deficiencies of some lighter elements as well as large enrichments of heavy elements. A large fraction of sdB stars are found in close binaries with white dwarf or very low-mass main sequence companions, which must have gone through a common-envelope (CE) phase of evolution. Because the binaries are detached they provide a clean-cut laboratory to study this important but yet poorly understood phase of stellar evolution. Hot subdwarf binaries with sufficiently massive white dwarf companions are viable candidate progenitors of type Ia supernovae both in the double degenerate as well as in the single degenerate scenario as helium donors for double detonation supernovae. The hyper-velocity He-sdO star US 708 may be the surviving donor of such a double detonation supernova. Substellar companions to sdB stars have also been found. For HW Vir systems the companion mass distribution extends from the stellar into the brown dwarf regime. A giant planet to the acoustic-mode pulsator V391 Peg was the first discovery of a planet that survived the red giant evolution of its host star. Evidence for Earth-size planets to two pulsating sdB stars have been reported and circumbinary giant planets or brown dwarfs have been found around HW Vir systems from eclipse timings. The high incidence of circumbinary substellar objects suggests that most of the planets are formed from the remaining CE material (second generation planets). Several types of pulsating star have been discovered among hot subdwarf stars, the most common are the gravity-mode sdB pulsators (V1093 Her) and their hotter siblings, the p-mode pulsating V361 Hya stars. Another class of multi-periodic pulsating hot subdwarfs has been found in the globular cluster ω Cen that is unmatched by any field star. Asteroseismology has advanced enormously thanks to the high-precision Kepler photometry and allowed stellar rotation rates to be determined, the interior structure of gravity-mode pulsators to be probed and stellar ages to be estimated. Rotation rates turned out to be unexpectedly slow calling for very efficient angular momentum loss on the red giant branch or during the helium core flash. The convective cores were found to be larger than predicted by standard stellar evolution models requiring very efficient angular momentum transport on the red giant branch. The masses of hot subdwarf stars, both single or in binaries, are the key to understand the stars’ evolution. A few pulsating sdB stars in eclipsing binaries have been found that allow both techniques to be applied for mass determination. The results, though few, are in good agreement with predictions from binary population synthesis calculations. New classes of binaries, hosting so-called extremely low mass (ELM) white dwarfs (M < 0.3 M ⊙), have recently been discovered, filling a gap in the mosaic of binary stellar evolution. Like most sdB stars the ELM white dwarfs are the stripped cores of red giants, the known companions are either white dwarfs, neutron stars (pulsars) or F- or A-type main sequence stars (“EL CVn” stars). In the near future, the Gaia mission will provide high-precision astrometry for a large sample of subdwarf stars to disentangle the different stellar populations in the field and to compare the field subdwarf population with the globular clusters’ hot subdwarfs. New fast-moving subdwarfs will allow the mass of the Galactic dark matter halo to be constrained and additional unbound hyper-velocity stars may be discovered. Subdwarf O/B stars and extremely low mass white dwarfs: atmospheric parameters and abundances, formation and evolution, binaries, planetary companions, pulsation, and kinematics.
DEVELOPMENT OF A CALCIUM-BASED SORBENT FOR HOT GAS CLEANUP
DOE Office of Scientific and Technical Information (OSTI.GOV)
T.D. Wheelock; L.K. Doraiswamy; K. Constant
1999-10-01
The development and testing of potential calcium-based sorbents for hot gas cleanup continued. One of the most promising materials combines powdered limestone and a calcium aluminate cement by two step pelletization followed by steam curing. Reasonably strong pellets are produced with good adsorption characteristics by incorporating 20 wt.% cement in the core and 40 wt.% cement in the shell. The resulting 4.76 mm diameter pellets are capable of withstanding a crushing force approaching 11.5 N/mm before breaking and are also capable of removing H{sub 2}S from dilute, hot gas streams. The pellets are also regenerable and reusable. Another promising materialmore » combines calcium carbonate powder and finely ground calcined alumina in tablet form. The small tablets are prepared by mixing the materials with water to form a thick paste which is then molded and dried. The tablets are hardened by calcining at either 1000 to 1100 C. The resulting tablets are strong and capable of removing H{sub 2}S from a dilute, hot gas stream.« less
NASA Technical Reports Server (NTRS)
Moehler, S.; Sweigart, Allan V.; Landsman, W. B.; Dreizler, S.; Rabin, Douglas M. (Technical Monitor)
2002-01-01
(Omega) Cen contains the largest population of very hot horizontal branch (HB) stars known in a globular cluster. Recent UV observations (Whitney et al. 1998; D'Cruz et al. 2000) show a significant population of hot stars below the zero-age horizontal branch ("blue hook" stars), which cannot be explained by canonical stellar evolution. Stars which suffer unusually large mass loss on the red giant branch and thus experience the helium core flash while descending the white dwarf cooling curve could populate this region. Theory predicts that these "late hot flashers" should show higher temperatures than the hottest canonical HB stars and should have helium- and carbon-rich atmospheres. We obtained and analysed medium resolution spectra of a sample of blue hook stars to derive their atmospheric parameters. The blue hook stars are indeed both hotter (T(sub eff)>35,000 K) and more helium-rich than classical extreme HB stars. In addition we find indications for a large enhancement of the carbon abundance relative to the cluster abundance.
Weum, Sven; Mercer, James B; de Weerd, Louis
2016-07-15
The current gold standard for preoperative perforator mapping in breast reconstruction with a DIEP flap is CT angiography (CTA). Dynamic infrared thermography (DIRT) is an imaging method that does not require ionizing radiation or contrast injection. We evaluated if DIRT could be an alternative to CTA in perforator mapping. Twenty-five patients scheduled for secondary breast reconstruction with a DIEP flap were included. Preoperatively, the lower abdomen was examined with hand-held Doppler, DIRT and CTA. Arterial Doppler sound locations were marked on the skin. DIRT examination involved rewarming of the abdominal skin after a mild cold challenge. The locations of hot spots on DIRT were compared with the arterial Doppler sound locations. The rate and pattern of rewarming of the hot spots were analyzed. Multiplanar CT reconstructions were used to see if hot spots were related to perforators on CTA. All flaps were based on the perforator selected with DIRT and the surgical outcome was analyzed. First appearing hot spots were always associated with arterial Doppler sounds and clearly visible perforators on CTA. The hot spots on DIRT images were always slightly laterally located in relation to the exit points of the associated perforators through the rectus abdominis fascia on CTA. Some periumbilical perforators were not associated with hot spots and showed communication with the superficial inferior epigastric vein on CTA. The selected perforators adequately perfused all flaps. This study confirms that perforators selected with DIRT have arterial Doppler sound, are clearly visible on CTA and provide adequate perfusion for DIEP breast reconstruction. Retrospectively registered at ClinicalTrials.gov with identifier NCT02806518 .
Speedometry: A Vehicle for Promoting Interest and Engagement through Integrated STEM Instruction
ERIC Educational Resources Information Center
Sinatra, Gale M.; Mukhopadhyay, Ananya; Allbright, Taylor N.; Marsh, Julie A.; Polikoff, Morgan S.
2017-01-01
The curriculum, Hot Wheels Speedometry (Mattel, El Segundo, CA, USA), was designed to align with the Next Generation Science Standards for science and the Common Core State Standards for mathematics. Our objective was to develop, implement, and evaluate the impact of this integrated science, technology, engineering, and mathematics (STEM)…
Hot and Cool Executive Function: Foundations for Learning and Healthy Development
ERIC Educational Resources Information Center
Meuwissen, Alyssa S.; Zelazo, Philip David
2014-01-01
Executive function (EF) refers to the set of core self-regulatory skills required for deliberate, goal-directed problem solving. These skills, which are exercised when children pause and reflect before reacting, provide a foundation for learning in a classroom context. They make it possible to pay attention, think flexibly, keep information in…
Organic geochemistry of core samples from an ultradeep hot well (300°C, 7 km)
Price, Leigh C.
1982-01-01
Concepts prevelant among petroleum organic geochemists concerning the thermal fate of hydrocarbons, with subsequent graphite formation, and greenschist metamorphism, are in sharp contradiction to these data. Conventional concepts of the distribution of heavy hydrocarbons with increasing temperature and depth apparently require further review and revision.
Variation in Local-Scale Edge Effects: Mechanisms and landscape Context
Therese M. Donovan; Peter W. Jones; Elizabeth M. Annand; Frank R. Thompson III
1997-01-01
Ecological processes near habitat edges often differ from processes away from edges. Yet, the generality of "edge effects" has been hotly debated because results vary tremendously. To understand the factors responsible for this variation, we described nest predation and cowbird distribution patterns in forest edge and forest core habitats on 36 randomly...
Chemical evolution of molecular clouds
NASA Technical Reports Server (NTRS)
Prasad, Sheo S.; Tarafdar, Sankar P.; Villere, Karen R.; Huntress, Wesley T., Jr.
1987-01-01
The principles behind the coupled chemical-dynamical evolution of molecular clouds are described. Particular attention is given to current problems involving the simplest species (i.e., C. CO, O2, and H2) in quiescent clouds. The results of a comparison made between the molecular abundances in the Orion ridge and the hot core (Blake, 1986) are presented.
How One State Established School Library/Technology Standards
ERIC Educational Resources Information Center
Bartow, Colet
2009-01-01
Educational standards continue to be hot topics of discussion for this year and, no doubt, beyond. The Council of Chief State School Officials (CCSSO) and the National Governors' Association Center for Best Practices (NGA Center) has initiated a study based on "Common Core" English/Language Arts and Mathematics Standards. The release of…
Service-Learning: A Tool to Develop Employment Competencies for College Students
ERIC Educational Resources Information Center
Ramson, Amy J.
2014-01-01
College students will face a workplace transformed even from the one that existed five years ago. Public and private organizations presently require employees to possess highly developed core competencies. This shift in expectations, exacerbated by high unemployment among recent college graduates, has made accountability a hot issue for higher…
Is It Hot in Here? Thermoregulation and Homeostasis through an Exercise Activity
ERIC Educational Resources Information Center
Dean, Lewis G.; Breslin, Angela; Ross, Emma Z.
2014-01-01
Homeostasis, the control of an internal environment to maintain stable, relatively constant conditions, is a key concept in physiology. In endothermic species, including humans ("Homo sapiens"), the control of body temperature is fundamental to the control of a suitable internal environment. To help regulate core body temperature, the…
Does Wyoming's Core Area Policy Protect Winter Habitats for Greater Sage-Grouse?
Smith, Kurt T; Beck, Jeffrey L; Pratt, Aaron C
2016-10-01
Conservation reserves established to protect important habitat for wildlife species are used world-wide as a wildlife conservation measure. Effective reserves must adequately protect year-round habitats to maintain wildlife populations. Wyoming's Sage-Grouse Core Area policy was established to protect breeding habitats for greater sage-grouse (Centrocercus urophasianus). Protecting only one important seasonal habitat could result in loss or degradation of other important habitats and potential declines in local populations. The purpose of our study was to identify the timing of winter habitat use, the extent which individuals breeding in Core Areas used winter habitats, and develop resource selection functions to assess effectiveness of Core Areas in conserving sage-grouse winter habitats in portions of 5 Core Areas in central and north-central Wyoming during winters 2011-2015. We found that use of winter habitats occured over a longer period than current Core Area winter timing stipulations and a substantial amount of winter habitat outside of Core Areas was used by individuals that bred in Core Areas, particularly in smaller Core Areas. Resource selection functions for each study area indicated that sage-grouse were selecting habitats in response to landscapes dominated by big sagebrush and flatter topography similar to other research on sage-grouse winter habitat selection. The substantial portion of sage-grouse locations and predicted probability of selection during winter outside small Core Areas illustrate that winter requirements for sage-grouse are not adequately met by existing Core Areas. Consequently, further considerations for identifying and managing important winter sage-grouse habitats under Wyoming's Core Area Policy are warranted.
Leal-Acosta, María Luisa; Shumilin, Evgueni; Mirlean, Nicolai; Baturina, Elena Lounejeva; Sánchez-Rodríguez, Ignacio; Delgadillo-Hinojosa, Francisco; Borges-Souza, José
2018-03-01
We investigated the influence of the intertidal geothermal hot spring (GHS) on the biogeochemistry of trace elements in Santispac Bight, Bahía Concepción (Gulf of California). The geothermal fluids were enriched in As and Hg mainly in ionic form. The suspended particulate matter of the GHS had elevated enrichment factor (EF) >1 of As, Bi, Cd, Co, Cu, Mn, Mo, Sb, Sn, Sr, Ti, U and Zn. The sediment core from GHS1 had high concentration of As, Hg, C org , S, V, Mo, and U and the extremely high EF of these elements at 8cm of the core. The maximum bioaccumulation of As and Hg was in seaweeds Sargassum sinicola collected near the GHS2. The results confirm the input of trace elements to the coastal zone in Bahía Concepción from geothermal fluids and the evident modification of the chemical composition of the adjacent marine environment. Copyright © 2018 Elsevier Ltd. All rights reserved.
Unveiling the Hot Molecular Core in the Ultracompact H II Region with Extended Emission G12.21-0.10
NASA Astrophysics Data System (ADS)
de la Fuente, E.; Trinidad, M. A.; Porras, A.; Rodríguez-Rico, C.; Araya, E. D.; Kurtz, S.; Hofner, P.; Nigoche-Netro, A.
2018-04-01
We present a multiwavelength study of the cometary H II region G12.21-0.10 using the VLA and OVRO. Both radio continuum (0.3, 0.7, 2 and 3.6 cm) and spectral lines of H41α, 13CS(2-1) & (1-0), and NH3(2,2) & (4,4) observations are included. We find two 3 mm continuum peaks toward G12.21-0.10; one of them is spatially coincident with the UC H II region, while the other coincides spatially with a molecular clump. We also find that the 0.7, 2 and 3.6 cm continuum and H41α line are only detected toward the UC H II region, while the 13CS, and NH3 are spatially associated with the molecular clump. Based on the morphology, kinetic temperature (≍86 K), volumetric density (≍1.5×106 cm-3) and linear size (≍0.22 pc) of the molecular clump, we suggest this source is consistent with a hot molecular core.
a Search for Interstellar Urea with Carma
NASA Astrophysics Data System (ADS)
Kuo, H.-L.; Snyder, L. E.; Friedel, D. N.; Looney, L. W.; McCall, B. J.; Remijan, A. J.; Lovas, F. J.; Hollis, J. M.
2009-06-01
Urea, a molecule discovered in human urine by H. M Rouelle in 1773, also plays a significant role in prebiotic chemistry. Previous BIMA observations have suggested that interstellar urea [(NH_2)_2CO] is a compact hot core molecule such as the other large molecules methyl formate and acetic acid (2008, 63rd OSU Symposium On Molecular Spectroscopy, RF11). We have conducted an extensive search for urea toward the high mass hot molecular core Sgr B2(N-LMH) using the CARMA array. The resolution at 1 mm enables favorable coupling of source size and synthesized beam size, which was found to be essential for flux measurements and detection limits of weak signals. The 2.5^''×2^'' synthesized beam of CARMA significantly resolves out the extended emission and reveals the weak lines that were previously blended with nearby transitions. Our analysis indicates that these lines are likely to be urea since they are now less contaminated, the resulting observed line frequencies are coincident with a set of overlapping connecting urea lines, and the observed line intensities are consistent with expected line strengths of urea.
Sprint performance under heat stress: A review.
Girard, O; Brocherie, F; Bishop, D J
2015-06-01
Training and competition in major track-and-field events, and for many team or racquet sports, often require the completion of maximal sprints in hot (>30 °C) ambient conditions. Enhanced short-term (<30 s) power output or single-sprint performance, resulting from transient heat exposure (muscle temperature rise), can be attributed to improved muscle contractility. Under heat stress, elevations in skin/core temperatures are associated with increased cardiovascular and metabolic loads in addition to decreasing voluntary muscle activation; there is also compelling evidence to suggest that large performance decrements occur when repeated-sprint exercise (consisting of brief recovery periods between sprints, usually <60 s) is performed in hot compared with cool conditions. Conversely, poorer intermittent-sprint performance (recovery periods long enough to allow near complete recovery, usually 60-300 s) in hotter conditions is solely observed when exercise induces marked hyperthermia (core temperature >39 °C). Here we also discuss strategies (heat acclimatization, precooling, hydration strategies) employed by "sprint" athletes to mitigate the negative influence of higher environmental temperatures. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Revealing Thermal Instabilities in the Core of the Phoenix Cluster
NASA Astrophysics Data System (ADS)
McDonald, Michael
2017-08-01
The Phoenix cluster is the most relaxed cluster known, and hosts the strongest cool core of any cluster yet discovered. At the center of this cluster is a massive starburst galaxy, with a SFR of 500-1000 Msun/yr, seemingly satisfying the early cooling flow predictions, despite the presence of strong AGN feedback from the central supermassive black hole. Here we propose deep narrow-band imaging of the central 120 kpc of the cluster, to map the warm (10^4K) ionized gas via the [O II] emission line. In low-z clusters, such as Perseus and Abell 1795, the warm, ionized phase is of critical importance to map out thermal instabilities in the hot gas, and maps of Halpha and [O II] have been used for decades to understand how (and how not) cooling proceeds in the intracluster medium. The data proposed for here, combined with deep ALMA data, a recently-approved Large Chandra Program, and recently-approved multi-frequency JVLA data, will allow us to probe the cooling ICM, the cool, filamentary gas, the cold molecular gas, the star-forming population, and the AGN jets all on scales of <10 kpc. This multi-observatory campaign, focusing on the most extreme cooling cluster, will lead to a more complete understanding of how and why thermal instabilities develop in the hot ICM of cool core clusters.
NASA Astrophysics Data System (ADS)
Bose, A.; Betti, R.; Mangino, D.; Woo, K. M.; Patel, D.; Christopherson, A. R.; Gopalaswamy, V.; Mannion, O. M.; Regan, S. P.; Goncharov, V. N.; Edgell, D. H.; Forrest, C. J.; Frenje, J. A.; Gatu Johnson, M.; Yu Glebov, V.; Igumenshchev, I. V.; Knauer, J. P.; Marshall, F. J.; Radha, P. B.; Shah, R.; Stoeckl, C.; Theobald, W.; Sangster, T. C.; Shvarts, D.; Campbell, E. M.
2018-06-01
This paper describes a technique for identifying trends in performance degradation for inertial confinement fusion implosion experiments. It is based on reconstruction of the implosion core with a combination of low- and mid-mode asymmetries. This technique was applied to an ensemble of hydro-equivalent deuterium-tritium implosions on OMEGA which achieved inferred hot-spot pressures ≈56 ± 7 Gbar [Regan et al., Phys. Rev. Lett. 117, 025001 (2016)]. All the experimental observables pertaining to the core could be reconstructed simultaneously with the same combination of low and mid-modes. This suggests that in addition to low modes, which can cause a degradation of the stagnation pressure, mid-modes are present which reduce the size of the neutron and x-ray producing volume. The systematic analysis shows that asymmetries can cause an overestimation of the total areal density in these implosions. It is also found that an improvement in implosion symmetry resulting from correction of either the systematic mid or low modes would result in an increase in the hot-spot pressure from 56 Gbar to ≈ 80 Gbar and could produce a burning plasma when the implosion core is extrapolated to an equivalent 1.9 MJ symmetric direct illumination [Bose et al., Phys. Rev. E 94, 011201(R) (2016)].
Bose, A.; Betti, R.; Mangino, D.; ...
2018-05-29
This paper describes a technique for identifying trends in performance degradation for inertial con finement fusion implosion experiments. It is based on reconstruction of the implosion core with a combination of low- and mid-mode asymmetries. This technique was applied to an ensemble of hydro-equivalent deuterium-tritium implosions on OMEGA that achieved inferred hot-spot pressures ≈56 ± 7 Gbar [S. Regan et al., Phys. Rev. Lett. 117, 025001 (2016)]. All the experimental observables pertaining to the core could be reconstructed simultaneously with the same combination of low and mid modes. This suggests that in addition to low modes, that can cause amore » degradation of the stagnation pressure, mid modes are present that reduce the size of the neutron and x-ray producing volume. The systematic analysis shows that asymmetries can cause an overestimation of the total areal density in these implosions. Finally, it is also found that an improvement in implosion symmetry resulting from correction of either the systematic mid or low modes would result in an increase of the hot-spot pressure from 56 Gbar to ≈ 80 Gbar and could produce a burning plasma when the implosion core is extrapolated to an equivalent 1.9 MJ symmetric direct illumination [A. Bose et al., Phys. Rev. E 94, 011201(R) (2016)].« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bose, A.; Betti, R.; Mangino, D.
This paper describes a technique for identifying trends in performance degradation for inertial con finement fusion implosion experiments. It is based on reconstruction of the implosion core with a combination of low- and mid-mode asymmetries. This technique was applied to an ensemble of hydro-equivalent deuterium-tritium implosions on OMEGA that achieved inferred hot-spot pressures ≈56 ± 7 Gbar [S. Regan et al., Phys. Rev. Lett. 117, 025001 (2016)]. All the experimental observables pertaining to the core could be reconstructed simultaneously with the same combination of low and mid modes. This suggests that in addition to low modes, that can cause amore » degradation of the stagnation pressure, mid modes are present that reduce the size of the neutron and x-ray producing volume. The systematic analysis shows that asymmetries can cause an overestimation of the total areal density in these implosions. Finally, it is also found that an improvement in implosion symmetry resulting from correction of either the systematic mid or low modes would result in an increase of the hot-spot pressure from 56 Gbar to ≈ 80 Gbar and could produce a burning plasma when the implosion core is extrapolated to an equivalent 1.9 MJ symmetric direct illumination [A. Bose et al., Phys. Rev. E 94, 011201(R) (2016)].« less
Current Sheet Structures Observed by the TESIS EUV Telescope during a Flux Rope Eruption on the Sun
NASA Astrophysics Data System (ADS)
Reva, A. A.; Ulyanov, A. S.; Kuzin, S. V.
2016-11-01
We use the TESIS EUV telescope to study the current sheet signatures observed during flux rope eruption. The special feature of the TESIS telescope was its ability to image the solar corona up to a distance of 2 {R}⊙ from the Sun’s center in the Fe 171 Å line. The Fe 171 Å line emission illuminates the magnetic field lines, and the TESIS images reveal the coronal magnetic structure at high altitudes. The analyzed coronal mass ejection (CME) had a core with a spiral—flux rope—structure. The spiral shape indicates that the flux rope radius varied along its length. The flux rope had a complex temperature structure: cold legs (70,000 K, observed in He 304 Å line) and a hotter core (0.7 MK, observed in Fe 171 Å line). Such a structure contradicts the common assumption that the CME core is a cold prominence. When the CME impulsively accelerated, a dark double Y-structure appeared below the flux rope. The Y-structure timing, location, and morphology agree with the previously performed MHD simulations of the current sheet. We interpreted the Y-structure as a hot envelope of the current sheet and hot reconnection outflows. The Y-structure had a thickness of 6.0 Mm. Its length increased over time from 79 Mm to more than 411 Mm.
EXTERNALLY HEATED PROTOSTELLAR CORES IN THE OPHIUCHUS STAR-FORMING REGION
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lindberg, Johan E.; Charnley, Steven B.; Cordiner, Martin A.
We present APEX 218 GHz observations of molecular emission in a complete sample of embedded protostars in the Ophiuchus star-forming region. To study the physical properties of the cores, we calculate H{sub 2}CO and c -C{sub 3}H{sub 2} rotational temperatures, both of which are good tracers of the kinetic temperature of the molecular gas. We find that the H{sub 2}CO temperatures range between 16 K and 124 K, with the highest H{sub 2}CO temperatures toward the hot corino source IRAS 16293-2422 (69–124 K) and the sources in the ρ Oph A cloud (23–49 K) located close to the luminous Herbigmore » Be star S1, which externally irradiates the ρ Oph A cores. On the other hand, the c -C{sub 3}H{sub 2} rotational temperature is consistently low (7–17 K) in all sources. Our results indicate that the c -C{sub 3}H{sub 2} emission is primarily tracing more shielded parts of the envelope whereas the H{sub 2}CO emission (at the angular scale of the APEX beam; 3600 au in Ophiuchus) mainly traces the outer irradiated envelopes, apart from in IRAS 16293-2422, where the hot corino emission dominates. In some sources, a secondary velocity component is also seen, possibly tracing the molecular outflow.« less
Exploring Manycore Multinode Systems for Irregular Applications with FPGA Prototyping
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ceriani, Marco; Palermo, Gianluca; Secchi, Simone
We present a prototype of a multi-core architecture implemented on FPGA, designed to enable efficient execution of irregular applications on distributed shared memory machines, while maintaining high performance on regular workloads. The architecture is composed of off-the-shelf soft-core cores, local interconnection and memory interface, integrated with custom components that optimize it for irregular applications. It relies on three key elements: a global address space, multithreading, and fine-grained synchronization. Global addresses are scrambled to reduce the formation of network hot-spots, while the latency of the transactions is covered by integrating an hardware scheduler within the custom load/store buffers to take advantagemore » from the availability of multiple executions threads, increasing the efficiency in a transparent way to the application. We evaluated a dual node system irregular kernels showing scalability in the number of cores and threads.« less
Hot melt adhesive attachment pad
NASA Technical Reports Server (NTRS)
Fox, R. L.; Frizzill, A. W.; Little, B. D.; Progar, D. J.; Coultrip, R. H.; Couch, R. H.; Gleason, J. R.; Stein, B. A.; Buckley, J. D.; St.clair, T. L. (Inventor)
1984-01-01
A hot melt adhesive attachment pad for releasably securing distinct elements together is described which is particularly useful in the construction industry or a spatial vacuum environment. The attachment pad consists primarily of a cloth selectively impregnated with a charge of hot melt adhesive, a thermo-foil heater, and a thermo-cooler. These components are securely mounted in a mounting assembly. In operation, the operator activates the heating cycle transforming the hot melt adhesive to a substantially liquid state, positions the pad against the attachment surface, and activates the cooling cycle solidifying the adhesive and forming a strong, releasable bond.
DOT National Transportation Integrated Search
1999-11-01
Connecticut Department of Transportation personnel used an infrared camera to observe thermal segregation of hot mix asphalt during pavement construction. Several sites were selected for study from ongoing paving projects. During paving operations, t...
Solar Space and Water Heating for Hospital --Charlottesville, Virginia
NASA Technical Reports Server (NTRS)
1982-01-01
Solar heating system described in an 86-page report consists of 88 single-glazed selectively-coated baseplate collector modules, hot-water coils in air ducts, domestic-hot-water preheat tank, 3,000 Gallon (11,350-1) concrete urethane-insulated storage tank and other components.
Mean Streets and Mental Health: Depression and Post-Traumatic Stress Disorder at Crime Hot Spots.
Weisburd, David; Cave, Breanne; Nelson, Matthew; White, Clair; Haviland, Amelia; Ready, Justin; Lawton, Brian; Sikkema, Kathleen
2018-03-07
This study explores the relationship between mental health and place at microgeographic units of analysis. We examine self-reported symptomology for depression and PTSD for 2,724 survey respondents interviewed in three types of randomly selected street segments: violent crime hot spots, cool spots, and cold spots. We find that the mean symptomology score is 61% higher for depression in violent crime hot spots than cold spots, and 85% higher for PTSD. Overall, we estimate that 14.8% of residents of violent crime hot spots meet thresholds for moderate depression or a diagnosis of PTSD. This can be compared to only 6.5% of residents at the cold spots. Using PSM and weighted negative binomial regression approaches we show that observable selection factors are not responsible for the relationships identified. Examining geographic influences, we find an important area effect of violent crime for both mental health measures, and an additional impact of the specific street of residence for PTSD. © Society for Community Research and Action 2018.
Mihiretu, Gezahegn T; Brodin, Malin; Chimphango, Annie F; Øyaas, Karin; Hoff, Bård H; Görgens, Johann F
2017-10-01
The viability of single-step microwave-induced pressurized hot water conditions for co-production of xylan-based biopolymers and bioethanol from aspenwood sawdust and sugarcane trash was investigated. Extraction of hemicelluloses was conducted using microwave-assisted pressurized hot water system. The effects of temperature and time on extraction yield and enzymatic digestibility of resulting solids were determined. Temperatures between 170-200°C for aspenwood and 165-195°C for sugarcane trash; retention times between 8-22min for both feedstocks, were selected for optimization purpose. Maximum xylan extraction yields of 66 and 50%, and highest cellulose digestibilities of 78 and 74%, were attained for aspenwood and sugarcane trash respectively. Monomeric xylose yields for both feedstocks were below 7%, showing that the xylan extracts were predominantly in non-monomeric form. Thus, single-step microwave-assisted hot water method is viable biorefinery approach to extract xylan from lignocelluloses while rendering the solid residues sufficiently digestible for ethanol production. Copyright © 2017 Elsevier Ltd. All rights reserved.
Action Memorandum for Decommissioning of TAN-607 Hot Shop Area
DOE Office of Scientific and Technical Information (OSTI.GOV)
M. A. Pinzel
The Department of Energy is documenting the selection of an alternative for the TAN-607 Hot Shop Area using a Comprehensive Environmental Response, Compensation, and Liability Act non-time-critical removal action (NTCRA). The scope of the removal action is limited to TAN-607 Hot Shop Area. An engineering evaluation/cost analysis (EE/CA) has assisted the Department of Energy Idaho Operations Office in identifuomg the most effective method for performing the decommissioning of this structure whose mission has ended. TAN-607 Hot Shop Area is located at Test Area North Technical Support Facility within the Idaho National Laboratory Site. The selected alternative consists of demolishing themore » TAN-607 aboveground structures and components, removing belowground noninert components (e.g. wood products), and removing the radiologically contaminated debris that does not meet remedial action objectives (RAOs), as defined in the Record of Decision Amendment for the V-Tanks and Explanation of Significant Differences for the PM-2A Tanks at Test Area North, Operable Unit 1-10.« less
Thiophene-Core Estrogen Receptor Ligands Having Superagonist Activity
Min, Jian; Wang, Pengcheng; Srinivasan, Sathish; Nwachukwu, Jerome C.; Guo, Pu; Huang, Minjian; Carlson, Kathryn E.; Katzenellenbogen, John A.; Nettles, Kendall W.; Zhou, Hai-Bing
2013-01-01
To probe the importance of the heterocyclic core of estrogen receptor (ER) ligands, we prepared a series of thiophene-core ligands by Suzuki cross-coupling of aryl boronic acids with bromo-thiophenes, and we assessed their receptor binding and cell biological activities. The disposition of the phenol substituents on the thiophene core, at alternate or adjacent sites, and the nature of substituents on these phenols all contribute to binding affinity and subtype selectivity. Most of the bis(hydroxyphenyl)-thiophenes were ERβ selective, whereas the tris(hydroxyphenyl)-thiophenes were ERα selective; analogous furan-core compounds generally have lower affinity and less selectivity. Some diarylthiophenes show distinct superagonist activity in reporter gene assays, giving maximal activities 2–3 times that of estradiol, and modeling suggests that these ligands have a different interaction with a hydrogen-bonding residue in helix-11. Ligand-core modification may be a new strategy for developing ER ligands whose selectivity is based on having transcriptional activity greater than that of estradiol. PMID:23586645
NORTH PORTAL-HOT WATER CIRCULATION PUMP CALCULATION-SHOP BUILDING #5006
DOE Office of Scientific and Technical Information (OSTI.GOV)
R. Blackstone
1996-01-25
The purpose of this design analysis and calculation is to size a circulating pump for the service hot water system in the Shop Building 5006, in accordance with the Uniform Plumbing Code (Section 4.4.1) and U.S. Department of Energy Order 6430.1A-1540 (Section 4.4.2). The method used for the calculation is based on Reference 5.2. This consists of determining the total heat transfer from the service hot water system piping to the surrounding environment. The heat transfer is then used to define the total pumping capacity based on a given temperature change in the circulating hot water as it flows throughmore » the closed loop piping system. The total pumping capacity is used to select a pump model from manufacturer's literature. This established the head generation for that capacity and particular pump model. The total length of all hot water supply and return piping including fittings is then estimated from the plumbing drawings which defines the pipe friction losses that must fit within the available pump head. Several iterations may be required before a pump can be selected that satisfies the head-capacity requirements.« less
Vermette, C J; Henrikson, Z A; Schwean-Lardner, K V; Crowe, T G
2017-09-01
The influence of hot conditions on 12-week-old turkey hens and 16-week-old toms while crated at transport density was evaluated. Forty-eight hens and 48 toms (8 birds per flock × 3 flocks × 2 humidity levels) were used in neutral treatments (trt; 20°C), and 16 hens and 16 toms (8 birds per flock × 1 flock × 2 humidity levels) were used in the hot trt (35°C). Birds were placed in crates at a transport stocking density of approximately 83 kg/m2, then inside a pre-conditioned chamber for 8 hours. Live shrink, core body temperature (CBT), heterophil/lymphocyte (H/L) ratio, and breast and thigh pH and color were recorded. Differences were declared significant at P ≤ 0.05. Live shrink after exposure to the 35°C trt (4.92%) was greater (P < 0.0001) than when birds were exposed to 20°C (1.48%). The 35°C trt (P < 0.0001) had higher Δ CBT (final minus initial) compared to the 20°C trt. The 35°C trt also caused higher (P < 0.0001) H/L ratio, 4.07 vs. 1.57 for the 20°C trt. Breast (P = 0.0110) and thigh pH levels (P < 0.0001) measured 27 h postmortem were lower for the 35°C trt at 5.64 and 5.73 compared to the 20°C trt at 5.70 and 5.92, respectively. Breast meat from birds exposed to 35°C was darker (P < 0.0001), while the color of thigh meat was unaffected. Toms quickly became distressed in the hot conditions, forcing those tests to be aborted. Only CBT data were analyzed. The CBT increased at a mean rate of 0.09°C/min for hens at both RH levels, while the CBT of toms increased at 0.12 and 0.18°C/min when exposed to 35°C, 30%; and 35°C, 80%, respectively. Exposure to hot temperatures caused higher CBT, greater live shrink, and greater H/L ratio. Toms were more greatly affected than hens to the hot trt, with CBT increasing at a greater rate. © 2017 Poultry Science Association Inc.
NASA Astrophysics Data System (ADS)
O'Sullivan, Ewan; Ponman, Trevor J.; Kolokythas, Konstantinos; Raychaudhury, Somak; Babul, Arif; Vrtilek, Jan M.; David, Laurence P.; Giacintucci, Simona; Gitti, Myriam; Haines, Chris P.
2017-12-01
We present the Complete Local-Volume Groups Sample (CLoGS), a statistically complete optically selected sample of 53 groups within 80 Mpc. Our goal is to combine X-ray, radio and optical data to investigate the relationship between member galaxies, their active nuclei and the hot intra-group medium (IGM). We describe sample selection, define a 26-group high-richness subsample of groups containing at least four optically bright (log LB ≥ 10.2 LB⊙) galaxies, and report the results of XMM-Newton and Chandra observations of these systems. We find that 14 of the 26 groups are X-ray bright, possessing a group-scale IGM extending at least 65 kpc and with luminosity >1041 erg s-1, while a further three groups host smaller galaxy-scale gas haloes. The X-ray bright groups have masses in the range M500 ≃ 0.5-5 × 1013 M⊙, based on system temperatures of 0.4-1.4 keV, and X-ray luminosities in the range 2-200 × 1041 erg s-1. We find that ∼53-65 per cent of the X-ray bright groups have cool cores, a somewhat lower fraction than found by previous archival surveys. Approximately 30 per cent of the X-ray bright groups show evidence of recent dynamical interactions (mergers or sloshing), and ∼35 per cent of their dominant early-type galaxies host active galactic nuclei with radio jets. We find no groups with unusually high central entropies, as predicted by some simulations, and confirm that CLoGS is in principle capable of detecting such systems. We identify three previously unrecognized groups, and find that they are either faint (LX, R500 < 1042 erg s-1) with no concentrated cool core, or highly disturbed. This leads us to suggest that ∼20 per cent of X-ray bright groups in the local universe may still be unidentified.
Kato, Hiroshi; Nakagawa, Kan-Ichi
2010-01-01
Core carrier techniques are unique among the various root canal filling techniques for delivering and compacting gutta-percha in the prepared root canal system. Thermafil (TF), considered the major core carrier device, is provided as an obturator consisting of a master core coated with thermoplasticized gutta-percha. We have devised a thermoplasticized gutta-percha filling technique using a polypropylene core, FlexPoint® NEO (FP), which was developed as a canal filling material that can be sterilized in an autoclave. Therefore, FP can be coated onto thermoplasticized gutta-percha and inserted into the prepared canal as a core carrier. The FP core carrier technique offers many advantages over the TF system: the core can be tested in the root canal and verified radiographically; the core can be adjusted to fit and surplus material easily removed; furthermore the core can be easily removed for retreatment. The clinical procedure of the FP core carrier technique is simple, and similar that with the TF system. Thermoplasticized gutta-percha in a syringe is heated in an oven and extruded onto the FP core carrier after a trial insertion. The FP core carrier is inserted into the root canal to the working length. Excess FP is then removed with a red-hot plastic instrument at the orifice of the root canal. The FP core carrier technique incorporates the clinical advantages of the existing TF system while minimizing the disadvantages. Hence the FP core carrier technique is very useful in clinical practice. This paper describes the FP core carrier technique as a new core based method.
Vincent, Grace E; Aisbett, Brad; Larsen, Brianna; Ridgers, Nicola D; Snow, Rod; Ferguson, Sally A
2017-02-12
This study was designed to examine the effects of ambient heat on firefighters' physical task performance, and physiological and perceptual responses when sleep restricted during simulated wildfire conditions. Thirty firefighters were randomly allocated to the sleep restricted ( n = 17, SR; 19 °C, 4-h sleep opportunity) or hot and sleep restricted ( n = 13, HOT + SR; 33 °C, 4-h sleep opportunity) condition. Firefighters performed two days of simulated, intermittent, self-paced work circuits comprising six firefighting tasks. Heart rate, and core temperature were measured continuously. After each task, firefighters reported their rating of perceived exertion and thermal sensation. Effort sensation was also reported after each work circuit. Fluids were consumed ad libitum. Urine volume and urine specific gravity were analysed. Sleep was monitored using polysomnography. There were no differences between the SR and HOT + SR groups in firefighters' physiological responses, hydration status, ratings of perceived exertion, motivation, and four of the six firefighting tasks (charged hose advance, rake, hose rolling, static hose hold). Black out hose and lateral repositioning were adversely affected in the HOT + SR group. Working in hot conditions did not appear to consistently impair firefighters work performance, physiology, and perceptual responses. Future research should determine whether such findings remain true when individual tasks are performed over longer durations.
Hot subdwarfs formed from the merger of two He white dwarfs
NASA Astrophysics Data System (ADS)
Schwab, Josiah
2018-06-01
We perform stellar evolution calculations of the remnant of the merger of two He white dwarfs (WDs). Our initial conditions are taken from hydrodynamic simulations of double WD mergers and the viscous disc phase that follows. We evolve these objects from shortly after the merger into their core He-burning phase, when they appear as hot subdwarf stars. We use our models to quantify the amount of H that survives the merger, finding that it is difficult for ≳ 10^{-4} M_{⊙} of H to survive, with even less being concentrated in the surface layers of the object. We also study the rotational evolution of these merger remnants. We find that mass-loss over the {˜ } 10^4 yr following the merger can significantly reduce the angular momentum of these objects. As hot subdwarfs, our models have moderate surface rotation velocities of 30-100 km s-1. The properties of our models are not representative of many apparently isolated hot subdwarfs, suggesting that those objects may form via other channels or that our modelling is incomplete. However, a sub-population of hot subdwarfs are moderate-to-rapid rotators and/or have He-rich atmospheres. Our models help to connect the observed properties of these objects to their progenitor systems.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Labrousse, M.; Lerouge, B.; Dupuy, G.
1978-04-01
THERMOS is a water reactor designed to provide hot water up to 120/sup 0/C for district heating or for desalination applications. It is a 100-MW reactor based on proven technology: oxide fuel plate elements, integrated primary circuit, and reactor vessel located in the bottom of a pool. As in swimming pool reactors, the pool is used for biological shielding, emergency core cooling, and fission product filtering (in case of an accident). Before economics, safety is the main characteristic of the concept: no fuel failure admitted, core under water in any accidental configuration, inspection of every ''nuclear'' component, and double-wall containment.
Protective claddings for high strength chromium alloys
NASA Technical Reports Server (NTRS)
Collins, J. F.
1971-01-01
The application of a Cr-Y-Hf-Th alloy as a protective cladding for a high strength chromium alloy was investigated for its effectiveness in inhibiting nitrogen embrittlement of a core alloy. Cladding was accomplished by a combination of hot gas pressure bonding and roll cladding techniques. Based on bend DBTT, the cladding alloy was effective in inhibiting nitrogen embrittlement of the chromium core alloy for up to 720 ks (200hours) in air at 1422 K (2100 F). A significant increase in the bend DBTT occurred with longer time exposures at 1422 K or short time exposures at 1589 K (2400 F).
Core formation and core composition from coupled geochemical and geophysical constraints
Badro, James; Brodholt, John P.; Piet, Helene; ...
2015-09-21
The formation of Earth’s core left behind geophysical and geochemical signatures in both the core and mantle that remain to this day. Seismology requires that the core be lighter than pure iron and therefore must contain light elements, and the geochemistry of mantle-derived rocks reveals extensive siderophile element depletion and fractionation. Both features are inherited from metal–silicate differentiation in primitive Earth and depend upon the nature of physiochemical conditions that prevailed during core formation. To date, core formation models have only attempted to address the evolution of core and mantle compositional signatures separately, rather than seeking a joint solution. Heremore » we combine experimental petrology, geochemistry, mineral physics and seismology to constrain a range of core formation conditions that satisfy both constraints. We find that core formation occurred in a hot (liquidus) yet moderately deep magma ocean not exceeding 1,800 km depth, under redox conditions more oxidized than present-day Earth. This new scenario, at odds with the current belief that core formation occurred under reducing conditions, proposes that Earth’s magma ocean started oxidized and has become reduced through time, by oxygen incorporation into the core. As a result, this core formation model produces a core that contains 2.7–5% oxygen along with 2–3.6% silicon, with densities and velocities in accord with radial seismic models, and leaves behind a silicate mantle that matches the observed mantle abundances of nickel, cobalt, chromium, and vanadium.« less
Core formation and core composition from coupled geochemical and geophysical constraints
DOE Office of Scientific and Technical Information (OSTI.GOV)
Badro, James; Brodholt, John P.; Piet, Helene
The formation of Earth’s core left behind geophysical and geochemical signatures in both the core and mantle that remain to this day. Seismology requires that the core be lighter than pure iron and therefore must contain light elements, and the geochemistry of mantle-derived rocks reveals extensive siderophile element depletion and fractionation. Both features are inherited from metal–silicate differentiation in primitive Earth and depend upon the nature of physiochemical conditions that prevailed during core formation. To date, core formation models have only attempted to address the evolution of core and mantle compositional signatures separately, rather than seeking a joint solution. Heremore » we combine experimental petrology, geochemistry, mineral physics and seismology to constrain a range of core formation conditions that satisfy both constraints. We find that core formation occurred in a hot (liquidus) yet moderately deep magma ocean not exceeding 1,800 km depth, under redox conditions more oxidized than present-day Earth. This new scenario, at odds with the current belief that core formation occurred under reducing conditions, proposes that Earth’s magma ocean started oxidized and has become reduced through time, by oxygen incorporation into the core. As a result, this core formation model produces a core that contains 2.7–5% oxygen along with 2–3.6% silicon, with densities and velocities in accord with radial seismic models, and leaves behind a silicate mantle that matches the observed mantle abundances of nickel, cobalt, chromium, and vanadium.« less
Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment
Kim, E-S; Elbeltagy, A R; Aboul-Naga, A M; Rischkowsky, B; Sayre, B; Mwacharo, J M; Rothschild, M F
2016-01-01
Goats and sheep are versatile domesticates that have been integrated into diverse environments and production systems. Natural and artificial selection have shaped the variation in the two species, but natural selection has played the major role among indigenous flocks. To investigate signals of natural selection, we analyzed genotype data generated using the caprine and ovine 50K SNP BeadChips from Barki goats and sheep that are indigenous to a hot arid environment in Egypt's Coastal Zone of the Western Desert. We identify several candidate regions under selection that spanned 119 genes. A majority of the genes were involved in multiple signaling and signal transduction pathways in a wide variety of cellular and biochemical processes. In particular, selection signatures spanning several genes that directly or indirectly influenced traits for adaptation to hot arid environments, such as thermo-tolerance (melanogenesis) (FGF2, GNAI3, PLCB1), body size and development (BMP2, BMP4, GJA3, GJB2), energy and digestive metabolism (MYH, TRHDE, ALDH1A3), and nervous and autoimmune response (GRIA1, IL2, IL7, IL21, IL1R1) were identified. We also identified eight common candidate genes under selection in the two species and a shared selection signature that spanned a conserved syntenic segment to bovine chromosome 12 on caprine and ovine chromosomes 12 and 10, respectively, providing, most likely, the evidence for selection in a common environment in two different but closely related species. Our study highlights the importance of indigenous livestock as model organisms for investigating selection sweeps and genome-wide association mapping. PMID:26555032
High Spectral Resolution SOFIA/EXES Observations of C2H2 toward Orion IRc2
NASA Astrophysics Data System (ADS)
Rangwala, Naseem; Colgan, Sean W. J.; Le Gal, Romane; Acharyya, Kinsuk; Huang, Xinchuan; Lee, Timothy J.; Herbst, Eric; deWitt, Curtis; Richter, Matt; Boogert, Adwin; McKelvey, Mark
2018-03-01
We present high spectral resolution observations from 12.96 to 13.33 microns toward Orion IRc2 using the mid-infrared spectrograph, Echelon-Cross-Echelle Spectrograph (EXES), at Stratospheric Observatory for Infrared Astronomy (SOFIA). These observations probe the physical and chemical conditions of the Orion hot core, which is sampled by a bright, compact, mid-infrared background continuum source in the region, IRc2. All 10 of the rovibrational C2H2 transitions expected in our spectral coverage are detected with high signal-to-noise ratios (S/Ns), yielding continuous coverage of the R-branch lines from J = 9–8 to J = 18–17, including both ortho and para species. Eight of these rovibrational transitions are newly reported detections. The isotopologue, 13CCH2, is clearly detected with a high S/N. This enabled a direct measurement of the 12C/13C isotopic ratio for the Orion hot core of 14 ± 1 and an estimated maximum value of 21. We also detected several HCN rovibrational lines. The ortho and para C2H2 ladders are clearly separate, and tracing two different temperatures, 226 K and 164 K, respectively, with a non-equilibrium ortho to para ratio (OPR) of 1.7 ± 0.1. Additionally, the ortho and para V LSR values differ by about 1.8 ± 0.2 km s‑1, while the mean line widths differ by 0.7 ± 0.2 km s‑1, suggesting that these species are not uniformly mixed along the line of sight to IRc2. We propose that the abnormally low C2H2 OPR could be a remnant from an earlier, colder phase, before the density enhancement (now the hot core) was impacted by shocks generated from an explosive event 500 years ago.
Active and passive heat stress similarly compromise tolerance to a simulated hemorrhagic challenge.
Pearson, J; Lucas, R A I; Schlader, Z J; Zhao, J; Gagnon, D; Crandall, C G
2014-10-01
Passive heat stress increases core and skin temperatures and reduces tolerance to simulated hemorrhage (lower body negative pressure; LBNP). We tested whether exercise-induced heat stress reduces LBNP tolerance to a greater extent relative to passive heat stress, when skin and core temperatures are similar. Eight participants (6 males, 32 ± 7 yr, 176 ± 8 cm, 77.0 ± 9.8 kg) underwent LBNP to presyncope on three separate and randomized occasions: 1) passive heat stress, 2) exercise in a hot environment (40°C) where skin temperature was moderate (36°C, active 36), and 3) exercise in a hot environment (40°C) where skin temperature was matched relative to that achieved during passive heat stress (∼38°C, active 38). LBNP tolerance was quantified using the cumulative stress index (CSI). Before LBNP, increases in core temperature from baseline were not different between trials (1.18 ± 0.20°C; P > 0.05). Also before LBNP, mean skin temperature was similar between passive heat stress (38.2 ± 0.5°C) and active 38 (38.2 ± 0.8°C; P = 0.90) trials, whereas it was reduced in the active 36 trial (36.6 ± 0.5°C; P ≤ 0.05 compared with passive heat stress and active 38). LBNP tolerance was not different between passive heat stress and active 38 trials (383 ± 223 and 322 ± 178 CSI, respectively; P = 0.12), but both were similarly reduced relative to active 36 (516 ± 147 CSI, both P ≤ 0.05). LBNP tolerance is not different between heat stresses induced either passively or by exercise in a hot environment when skin temperatures are similarly elevated. However, LBNP tolerance is influenced by the magnitude of the elevation in skin temperature following exercise induced heat stress. Copyright © 2014 the American Physiological Society.
Abundances of ethylene oxide and acetaldehyde in hot molecular cloud cores
NASA Technical Reports Server (NTRS)
Nummelin, A.; Dickens, J. E.; Bergman, P.; Hjalmarson, A.; Irvine, W. M.; Ikeda, M.; Ohishi, M.
1998-01-01
We have searched for millimetre-wave line emission from ethylene oxide (c-C2H4O) and its structural isomer acetaldehyde (CH3CHO) in 11 molecular clouds using SEST. Ethylene oxide and acetaldehyde were detected through multiple lines in the hot cores NGC 6334F, G327.3-0.6, G31.41+0.31, and G34.3+0.2. Acetaldehyde was also detected towards G10.47+0.03, G322.2+0.6, and Orion 3'N, and one ethylene oxide line was tentatively detected in G10.47+0.03. Column densities and rotational excitation temperatures were derived using a procedure which fits the observed line intensifies by finding the minimum chi 2-value. The resulting rotational excitation temperatures of ethylene oxide and acetaldehyde are in the range 16-38 K, indicating that these species are excited in the outer, cooler parts of the hot cores or that the excitation is significantly subthermal. For an assumed source size of 20", the deduced column densities are (0.6-1)x10(14) cm-2 for ethylene oxide and (2-5)x10(14) cm-2 for acetaldehyde. The fractional abundances with respect to H2 are X[c-C2H4O]=(2-6)xl0(-10), and X[CH3CHO]=(0.8-3)x10(-9). The ratio X[CH3CHO]/X[c-C2H4O] varies between 2.6 (NGC 6334F) and 8.5 (G327.3-0.6). We also detected and analysed multiple transitions of CH3OH, CH3OCH3, C2H5OH, and HCOOH. The chemical, and possibly evolutionary, states of NGC 6334F, G327.3-0.6, G31.41+0.31, and G34.3+0.2 seem to be very similar.
NASA Astrophysics Data System (ADS)
Fan, Lulu; Han, Yunkun; Nikutta, Robert; Drouart, Guillaume; Knudsen, Kirsten K.
2016-06-01
We utilize a Bayesian approach to fit the observed mid-IR-to-submillimeter/millimeter spectral energy distributions (SEDs) of 22 WISE-selected and submillimeter-detected, hyperluminous hot dust-obscured galaxies (Hot DOGs), with spectroscopic redshift ranging from 1.7 to 4.6. We compare the Bayesian evidence of a torus plusgraybody (Torus+GB) model with that of a torus-only (Torus) model and find that the Torus+GB model has higher Bayesian evidence for all 22 Hot DOGs than the torus-only model, which presents strong evidence in favor of the Torus+GB model. By adopting the Torus+GB model, we decompose the observed IR SEDs of Hot DOGs into torus and cold dust components. The main results are as follows. (1) Hot DOGs in our submillimeter-detected sample are hyperluminous ({L}{IR}≥slant {10}13{L}⊙ ), with torus emission dominating the IR energy output. However, cold dust emission is non-negligible, contributing on average ˜ 24% of total IR luminosity. (2) Compared to QSO and starburst SED templates, the median SED of Hot DOGs shows the highest luminosity ratio between mid-IR and submillimeter at rest frame, while it is very similar to that of QSOs at ˜ 10{--}50 μ {{m}}, suggesting that the heating sources of Hot DOGs should be buried AGNs. (3) Hot DOGs have high dust temperatures ({T}{dust}˜ 72 K) and high IR luminosity of cold dust. The {T}{dust}{--}{L}{IR} relation of Hot DOGs suggests that the increase in IR luminosity for Hot DOGs is mostly due to the increase of the dust temperature, rather than dust mass. Hot DOGs have lower dust masses than submillimeter galaxies (SMGs) and QSOs within a similar redshift range. Both high IR luminosity of cold dust and relatively low dust mass in Hot DOGs can be expected by their relatively high dust temperatures. (4) Hot DOGs have high dust-covering factors (CFs), which deviate from the previously proposed trend of the dust CF decreasing with increasing bolometric luminosity. Finally, we can reproduce the observed properties in Hot DOGs by employing a physical model of galaxy evolution. This result suggests that Hot DOGs may lie at or close to peaks of both star formation and black hole growth histories, and represent a transit phase during the evolutions of massive galaxies, transforming them from the dusty starburst-dominated phase to the optically bright QSO phase.
Laser patterning of diamond films
NASA Astrophysics Data System (ADS)
Narayan, J.; Chen, X.
1992-04-01
Selective deposition and fine-scale patterning of hot filament deposited diamond films by the use of pulsed laser irradiation on silicon and copper substrates are reported. The substrates were abraded with diamond and alumina powders before hot-filament chemical vapor deposition. A drastic enhancement in diamond nucleation (using hot-filament chemical vapor deposition) was observed on specimens treated with diamond powder, whereas enhancement on specimens pretreated with alumina powder was relatively insignificant. It is found that the seeding of diamond crystals was substantially reduced by pulsed laser annealing/melting which removes the plastic damage as well as the seed crystals introduced by diamond powder pretreatment. The selective deposition or fine-scale patterning of diamond films was achieved either by a shadow masking or by scanning a focused laser beam to generate desired patterns. The nucleation can also be enhanced by laser deposition of thin films, such as diamond-like carbon and tungsten carbide (WC), and selective deposition and patterning achieved by controlled removal or deposition of the above films.
Seismic Line Location Map Hot Pot Project, Humboldt County, Nevada 2010
Lane, Michael
2010-01-01
Seismic Line Location Map Hot Pot Project, Humboldt County, Nevada 2010. ArcGIS map package containing topographic base map, Township and Range layer, Oski BLM and private leases at time of survey, and locations, with selected shot points, of the five seismic lines.
Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting
Biegon, Anat
2018-05-30
The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.
Research on Estrogen and Behavior Is a "Hot Topic" at the 2011 Society for Neuroscience Meeting
DOE Office of Scientific and Technical Information (OSTI.GOV)
Biegon, Anat
The Society for Neuroscience has selected recent research on estrogen and its effect on behavior conducted at BNL for its "hot topics" book distributed to reporters attending the society's 2011 meeting in Washington, D.C., November 12-16.
GenoCore: A simple and fast algorithm for core subset selection from large genotype datasets.
Jeong, Seongmun; Kim, Jae-Yoon; Jeong, Soon-Chun; Kang, Sung-Taeg; Moon, Jung-Kyung; Kim, Namshin
2017-01-01
Selecting core subsets from plant genotype datasets is important for enhancing cost-effectiveness and to shorten the time required for analyses of genome-wide association studies (GWAS), and genomics-assisted breeding of crop species, etc. Recently, a large number of genetic markers (>100,000 single nucleotide polymorphisms) have been identified from high-density single nucleotide polymorphism (SNP) arrays and next-generation sequencing (NGS) data. However, there is no software available for picking out the efficient and consistent core subset from such a huge dataset. It is necessary to develop software that can extract genetically important samples in a population with coherence. We here present a new program, GenoCore, which can find quickly and efficiently the core subset representing the entire population. We introduce simple measures of coverage and diversity scores, which reflect genotype errors and genetic variations, and can help to select a sample rapidly and accurately for crop genotype dataset. Comparison of our method to other core collection software using example datasets are performed to validate the performance according to genetic distance, diversity, coverage, required system resources, and the number of selected samples. GenoCore selects the smallest, most consistent, and most representative core collection from all samples, using less memory with more efficient scores, and shows greater genetic coverage compared to the other software tested. GenoCore was written in R language, and can be accessed online with an example dataset and test results at https://github.com/lovemun/Genocore.
TOWARD CHEMICAL CONSTRAINTS ON HOT JUPITER MIGRATION
DOE Office of Scientific and Technical Information (OSTI.GOV)
Madhusudhan, Nikku; Amin, Mustafa A.; Kennedy, Grant M., E-mail: nmadhu@ast.cam.ac.uk
The origin of hot Jupiters—gas giant exoplanets orbiting very close to their host stars—is a long-standing puzzle. Planet formation theories suggest that such planets are unlikely to have formed in situ but instead may have formed at large orbital separations beyond the snow line and migrated inward to their present orbits. Two competing hypotheses suggest that the planets migrated either through interaction with the protoplanetary disk during their formation, or by disk-free mechanisms such as gravitational interactions with a third body. Observations of eccentricities and spin-orbit misalignments of hot Jupiter systems have been unable to differentiate between the two hypotheses.more » In the present work, we suggest that chemical depletions in hot Jupiter atmospheres might be able to constrain their migration mechanisms. We find that sub-solar carbon and oxygen abundances in Jovian-mass hot Jupiters around Sun-like stars are hard to explain by disk migration. Instead, such abundances are more readily explained by giant planets forming at large orbital separations, either by core accretion or gravitational instability, and migrating to close-in orbits via disk-free mechanisms involving dynamical encounters. Such planets also contain solar or super-solar C/O ratios. On the contrary, hot Jupiters with super-solar O and C abundances can be explained by a variety of formation-migration pathways which, however, lead to solar or sub-solar C/O ratios. Current estimates of low oxygen abundances in hot Jupiter atmospheres may be indicative of disk-free migration mechanisms. We discuss open questions in this area which future studies will need to investigate.« less
Exterior Companions to Hot Jupiters Orbiting Cool Stars Are Coplanar
NASA Astrophysics Data System (ADS)
Becker, Juliette C.; Vanderburg, Andrew; Adams, Fred C.; Khain, Tali; Bryan, Marta
2017-12-01
The existence of hot Jupiters has challenged theories of planetary formation since the first extrasolar planets were detected. Giant planets are generally believed to form far from their host stars, where volatile materials like water exist in their solid phase, making it easier for giant planet cores to accumulate. Several mechanisms have been proposed to explain how giant planets can migrate inward from their birth sites to short-period orbits. One such mechanism, called Kozai-Lidov migration, requires the presence of distant companions in orbits inclined by more than ˜40° with respect to the plane of the hot Jupiter’s orbit. The high occurrence rate of wide companions in hot-Jupiter systems lends support to this theory for migration. However, the exact orbital inclinations of these detected planetary and stellar companions is not known, so it is not clear whether the mutual inclination of these companions is large enough for the Kozai-Lidov process to operate. This paper shows that in systems orbiting cool stars with convective outer layers, the orbits of most wide planetary companions to hot Jupiters must be well aligned with the orbits of the hot Jupiters and the spins of the host stars. For a variety of possible distributions for the inclination of the companion, the width of the distribution must be less than ˜20° to recreate the observations with good fidelity. As a result, the companion orbits are likely well aligned with those of the hot Jupiters, and the Kozai-Lidov mechanism does not enforce migration in these systems.
Shukla, Harish; Singh, Sudhir Kumar; Singh, Amit Kumar; Mitra, Kalyan; Akhtar, Md Sohail
2015-09-23
The bacteriophage encoded hyaluronate lyases (HylP and HylP2) degrade hyaluronan and other glycosaminoglycans. HylP2 forms a functional fibril under acidic conditions in which its N-terminus is proposed to form the fibrillar core, leading to nucleation and acceleration of fibril formation. Here we report the presence of a hot spot region (A144GVVVY149) towards the carboxy terminus of HylP2, essential for the acceleration of fibril formation. The 'hot spot' is observed to be inherently mutated for valines (A178AMVMY183) in case of HylP. The N- terminal swapped chimeras between these phage HLs ((N)HylP2(C)HylP and (N)HylP(C)HylP2) or HylP did not form fibrils at acidic pH. However, seeding of prefibrils of HylP2 recompensed nucleation and led to fibrillation in (N)HylP(C)HylP2. The V147A mutation in the 'hot spot' region abolished fibril formation in HylP2. The M179V and M181V double mutations in the 'hot spot' region of HylP led to fibrillation with the seeding of prefibrils. It appears that fibrillation in HylP2 even though is initiated by the N-terminus, is accelerated by the conserved 'hot spot' region in the C-terminus. A collagenous (Gly-X-Y)10 motif in the N-terminus and a mutated 'hot spot' region in the C-terminus of HylP affect fibrillar nucleation and acceleration respectively.
Shukla, Harish; Singh, Sudhir Kumar; Singh, Amit Kumar; Mitra, Kalyan; Akhtar, Md. Sohail
2015-01-01
The bacteriophage encoded hyaluronate lyases (HylP and HylP2) degrade hyaluronan and other glycosaminoglycans. HylP2 forms a functional fibril under acidic conditions in which its N-terminus is proposed to form the fibrillar core, leading to nucleation and acceleration of fibril formation. Here we report the presence of a hot spot region (A144GVVVY149) towards the carboxy terminus of HylP2, essential for the acceleration of fibril formation. The ‘hot spot’ is observed to be inherently mutated for valines (A178AMVMY183) in case of HylP. The N- terminal swapped chimeras between these phage HLs (NHylP2CHylP and NHylPCHylP2) or HylP did not form fibrils at acidic pH. However, seeding of prefibrils of HylP2 recompensed nucleation and led to fibrillation in NHylPCHylP2. The V147A mutation in the ‘hot spot’ region abolished fibril formation in HylP2. The M179V and M181V double mutations in the ‘hot spot’ region of HylP led to fibrillation with the seeding of prefibrils. It appears that fibrillation in HylP2 even though is initiated by the N-terminus, is accelerated by the conserved ‘hot spot’ region in the C-terminus. A collagenous (Gly-X-Y)10 motif in the N-terminus and a mutated ‘hot spot’ region in the C-terminus of HylP affect fibrillar nucleation and acceleration respectively. PMID:26395159
Modeling of Texture Evolution During Hot Forging of Alpha/Beta Titanium Alloys (Preprint)
2007-06-01
treatment. The approach was validated via an industrial -scale trail comprising hot pancake forging of Ti- 6Al-4V. 15. SUBJECT TERMS titanium... industrial -scale trial comprising hot pancake forging of Ti-6Al-4V. Keywords: Titanium, Texture, Modeling, Strain Partitioning, Variant Selection... industrial -scale forging of Ti- 6Al-4V. 2. Background A brief review of pertinent previous efforts in the area of texture modeling is presented below
NASA Astrophysics Data System (ADS)
Knapik, Maciej
2018-02-01
The article presents an economic analysis and comparison of selected (district heating, natural gas, heat pump with renewable energy sources) methods for the preparation of domestic hot water in a building with low energy demand. In buildings of this type increased demand of energy for domestic hot water preparation in relation to the total energy demand can be observed. As a result, the proposed solutions allow to further lower energy demand by using the renewable energy sources. This article presents the results of numerical analysis and calculations performed mainly in MATLAB software, based on typical meteorological years. The results showed that system with heat pump and renewable energy sources Is comparable with district heating system.
Arima, Nobuyuki; Nishimura, Reiki; Osako, Tomofumi; Nishiyama, Yasuyuki; Fujisue, Mamiko; Okumura, Yasuhiro; Nakano, Masahiro; Tashima, Rumiko; Toyozumi, Yasuo
2016-01-01
In this case-control study, we investigated the most suitable cell counting area and the optimal cutoff point of the Ki-67 index. Thirty recurrent cases were selected among hormone receptor (HR)-positive/HER2-negative breast cancer patients. As controls, 90 nonrecurrent cases were randomly selected by allotting 3 controls to each recurrent case based on the following criteria: age, nodal status, tumor size, and adjuvant endocrine therapy alone. Both the hot spot and the average area of the tumor were evaluated on a Ki-67 immunostaining slide. The median Ki-67 index value at the hot spot and average area were 25.0 and 14.5%, respectively. Irrespective of the area counted, the Ki-67 index value was significantly higher in all of the recurrent cases (p < 0.0001). The multivariate analysis revealed that the Ki-67 index value of 20% at the hot spot was the most suitable cutoff point for predicting recurrence. Moreover, higher x0394;Ki-67 index value (the difference between the hot spot and the average area, ≥10%) and lower progesterone receptor expression (<20%) were significantly correlated with recurrence. A higher Ki-67 index value at the hot spot strongly correlated with recurrence, and the optimal cutoff point was found to be 20%. © 2015 S. Karger AG, Basel.
MnDOT thin whitetopping selection procedures : final report.
DOT National Transportation Integrated Search
2017-06-01
This report provides an integrated selection procedure for evaluating whether an existing hot-mix asphalt (HMA) pavement is an appropriate candidate for a bonded concrete overlay of asphalt (BCOA). The selection procedure includes (1) a desk review, ...
Electron Microscopy and Image Analysis for Selected Materials
NASA Technical Reports Server (NTRS)
Williams, George
1999-01-01
This particular project was completed in collaboration with the metallurgical diagnostics facility. The objective of this research had four major components. First, we required training in the operation of the environmental scanning electron microscope (ESEM) for imaging of selected materials including biological specimens. The types of materials range from cyanobacteria and diatoms to cloth, metals, sand, composites and other materials. Second, to obtain training in surface elemental analysis technology using energy dispersive x-ray (EDX) analysis, and in the preparation of x-ray maps of these same materials. Third, to provide training for the staff of the metallurgical diagnostics and failure analysis team in the area of image processing and image analysis technology using NIH Image software. Finally, we were to assist in the sample preparation, observing, imaging, and elemental analysis for Mr. Richard Hoover, one of NASA MSFC's solar physicists and Marshall's principal scientist for the agency-wide virtual Astrobiology Institute. These materials have been collected from various places around the world including the Fox Tunnel in Alaska, Siberia, Antarctica, ice core samples from near Lake Vostoc, thermal vents in the ocean floor, hot springs and many others. We were successful in our efforts to obtain high quality, high resolution images of various materials including selected biological ones. Surface analyses (EDX) and x-ray maps were easily prepared with this technology. We also discovered and used some applications for NIH Image software in the metallurgical diagnostics facility.
Thermal Characterization of Epoxy Adhesive by Hotfire Testing
NASA Technical Reports Server (NTRS)
Spomer, Ken A.; Haddock, M. Reed; McCool, Alex (Technical Monitor)
2001-01-01
This paper describes subscale solid-rocket motor hot-fire testing of epoxy adhesives in flame surface bondlines to evaluate heat-affected depth, char depth and ablation rate. Hot-fire testing is part of an adhesive down-selection program on the Space Shuttle Solid Rocket Motor Nozzle to provide additional confidence in the down-selected adhesives. The current nozzle structural adhesive bond system is being replaced due to obsolescence. Prior to hot-fire testing, adhesives were tested for chemical, physical and mechanical properties, which resulted in the selection of two potential replacement adhesives, Resin Technology Group's TIGA 321 and 3M's EC2615XLW. Hot-fire testing consisted of four forty-pound charge (FPC) motors fabricated in configurations that would allow side-by-side comparison testing of the candidate replacement adhesives with the current RSRM adhesives. Results of the FPC motor testing show that: 1) the phenolic char depths on radial bondlines is approximately the same and vary depending on the position in the blast tube regardless of which adhesive was used, 2) the replacement candidate adhesive char depths are equivalent to the char depths of the current adhesives, 3) the heat-affected depths of the candidate and current adhesives are equivalent, and 4) the ablation rates for both replacement adhesives were equivalent to the current adhesives.
Lefébure, Tristan; Stanhope, Michael J
2007-01-01
Background The genus Streptococcus is one of the most diverse and important human and agricultural pathogens. This study employs comparative evolutionary analyses of 26 Streptococcus genomes to yield an improved understanding of the relative roles of recombination and positive selection in pathogen adaptation to their hosts. Results Streptococcus genomes exhibit extreme levels of evolutionary plasticity, with high levels of gene gain and loss during species and strain evolution. S. agalactiae has a large pan-genome, with little recombination in its core-genome, while S. pyogenes has a smaller pan-genome and much more recombination of its core-genome, perhaps reflecting the greater habitat, and gene pool, diversity for S. agalactiae compared to S. pyogenes. Core-genome recombination was evident in all lineages (18% to 37% of the core-genome judged to be recombinant), while positive selection was mainly observed during species differentiation (from 11% to 34% of the core-genome). Positive selection pressure was unevenly distributed across lineages and biochemical main role categories. S. suis was the lineage with the greatest level of positive selection pressure, the largest number of unique loci selected, and the largest amount of gene gain and loss. Conclusion Recombination is an important evolutionary force in shaping Streptococcus genomes, not only in the acquisition of significant portions of the genome as lineage specific loci, but also in facilitating rapid evolution of the core-genome. Positive selection, although undoubtedly a slower process, has nonetheless played an important role in adaptation of the core-genome of different Streptococcus species to different hosts. PMID:17475002
Brown, Cameron S.; Zhang, Hongbin; Kucukboyaci, Vefa; ...
2016-09-07
VERA-CS (Virtual Environment for Reactor Applications, Core Simulator) is a coupled neutron transport and thermal-hydraulics subchannel code under development by the Consortium for Advanced Simulation of Light Water Reactors (CASL). VERA-CS was used to simulate a typical pressurized water reactor (PWR) full core response with 17x17 fuel assemblies for a main steam line break (MSLB) accident scenario with the most reactive rod cluster control assembly stuck out of the core. The accident scenario was initiated at the hot zero power (HZP) at the end of the first fuel cycle with return to power state points that were determined by amore » system analysis code and the most limiting state point was chosen for core analysis. The best estimate plus uncertainty (BEPU) analysis method was applied using Wilks’ nonparametric statistical approach. In this way, 59 full core simulations were performed to provide the minimum departure from nucleate boiling ratio (MDNBR) at the 95/95 (95% probability with 95% confidence level) tolerance limit. The results show that this typical PWR core remains within MDNBR safety limits for the MSLB accident.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brown, Cameron S.; Zhang, Hongbin; Kucukboyaci, Vefa
VERA-CS (Virtual Environment for Reactor Applications, Core Simulator) is a coupled neutron transport and thermal-hydraulics subchannel code under development by the Consortium for Advanced Simulation of Light Water Reactors (CASL). VERA-CS was used to simulate a typical pressurized water reactor (PWR) full core response with 17x17 fuel assemblies for a main steam line break (MSLB) accident scenario with the most reactive rod cluster control assembly stuck out of the core. The accident scenario was initiated at the hot zero power (HZP) at the end of the first fuel cycle with return to power state points that were determined by amore » system analysis code and the most limiting state point was chosen for core analysis. The best estimate plus uncertainty (BEPU) analysis method was applied using Wilks’ nonparametric statistical approach. In this way, 59 full core simulations were performed to provide the minimum departure from nucleate boiling ratio (MDNBR) at the 95/95 (95% probability with 95% confidence level) tolerance limit. The results show that this typical PWR core remains within MDNBR safety limits for the MSLB accident.« less
Gas Hydrate Exploration, Mid Chilean Coast; Geochemical-Geophysical Survey
2006-12-27
design for the piston core provided a more safe core delivery and retrieval protocol with changes in the messenger weight and triggering mechanism ...selection of samples that were analyzed onboard depended on key data needed to assist in sample station selection and the ability to transport and...weight and triggering mechanism . Through the cruise there were 17 piston coring attempts resulting in 15 successful cores. Failures in the core
Beyond the Core: The Hot Topic(al) Alternative to the Survey-Based Introduction to Sociology Course
Smith, R. Tyson
2011-01-01
In the following paper we argue that the conventional “Introduction to Sociology” survey course should be restructured because such courses try to survey an unsurveyable body of knowledge and they do not teach the application of sociological research. The conventional intro course should be replaced with an intro course that surveys the types of social dynamics that sociologists typically research and the methods they use to do so. We propose a semester-long intro course with four case study learning-units that are chosen for their coverage of the underlying sociological dynamics, methods, and core concepts. We contend that case study learning-units which concentrate on topical issues and core sociological concepts are better suited for an introduction course. PMID:21709825
Thermal baffle for fast-breeder reacton
Rylatt, John A.
1977-01-01
A liquid-metal-cooled fast-breeder reactor includes a bridge structure for separating hot outlet coolant from relatively cool inlet coolant consisting of an annular stainless steel baffle plate extending between the core barrel surrounding the core and the thermal liner associated with the reactor vessel and resting on ledges thereon, there being inner and outer circumferential webs on the lower surface of the baffle plate and radial webs extending between the circumferential webs, a stainless steel insulating plate completely covering the upper surface of the baffle plate and flex seals between the baffle plate and the ledges on which the baffle plate rests to prevent coolant from washing through the gaps therebetween. The baffle plate is keyed to the core barrel for movement therewith and floating with respect to the thermal liner and reactor vessel.
Pan, Yuliang; Wang, Zixiang; Zhan, Weihua; Deng, Lei
2018-05-01
Identifying RNA-binding residues, especially energetically favored hot spots, can provide valuable clues for understanding the mechanisms and functional importance of protein-RNA interactions. Yet, limited availability of experimentally recognized energy hot spots in protein-RNA crystal structures leads to the difficulties in developing empirical identification approaches. Computational prediction of RNA-binding hot spot residues is still in its infant stage. Here, we describe a computational method, PrabHot (Prediction of protein-RNA binding hot spots), that can effectively detect hot spot residues on protein-RNA binding interfaces using an ensemble of conceptually different machine learning classifiers. Residue interaction network features and new solvent exposure characteristics are combined together and selected for classification with the Boruta algorithm. In particular, two new reference datasets (benchmark and independent) have been generated containing 107 hot spots from 47 known protein-RNA complex structures. In 10-fold cross-validation on the training dataset, PrabHot achieves promising performances with an AUC score of 0.86 and a sensitivity of 0.78, which are significantly better than that of the pioneer RNA-binding hot spot prediction method HotSPRing. We also demonstrate the capability of our proposed method on the independent test dataset and gain a competitive advantage as a result. The PrabHot webserver is freely available at http://denglab.org/PrabHot/. leideng@csu.edu.cn. Supplementary data are available at Bioinformatics online.
Projected mortality from climate change-driven impacts on extremely hot and cold days increases significantly over the 21st century in a large group of United States Metropolitan Statistical Areas. Increases in projected mortality from more hot days are greater than decreases in ...
USDA-ARS?s Scientific Manuscript database
Surface energy fluxes, especially the latent heat flux from evapotranspiration (ET), determine exchanges of energy and mass between the hydrosphere, atmosphere, and biosphere. There are numerous remote sensing-based energy balance approaches such as METRIC and SEBAL that use hot and cold pixels from...
Fast saturation of the two-plasmon-decay instability for shock-ignition conditions
NASA Astrophysics Data System (ADS)
Weber, S.; Riconda, C.; Klimo, O.; Héron, A.; Tikhonchuk, V. T.
2012-01-01
Two-plasmon-decay (TPD) instability is investigated for conditions relevant for the shock-ignition (SI) scheme of inertial confinement fusion. Two-dimensional particle-in-cell simulations show that in a hot, large-scale plasma, TPD develops in concomitance with stimulated Raman scattering (SRS). It is active only during the first picosecond of interaction, and then it is rapidly saturated due to plasma cavitation. TPD-excited plasma waves extend to small wavelengths, above the standard Landau cutoff. The hot electron spectrum created by SRS and TPD is relatively soft, limited to energies below 100 keV, which should not be a danger for the fuel core preheat in the SI scenario.
NASA Astrophysics Data System (ADS)
Zaghloul, Mofreh R.
2018-03-01
We present estimates of the critical properties, thermodynamic functions, and principal shock Hugoniot of hot dense aluminum fluid as predicted from a chemical model for the equation-of-state of hot dense, partially ionized and partially degenerate plasma. The essential features of strongly coupled plasma of metal vapors, such as multiple ionization, Coulomb interactions among charged particles, partial degeneracy, and intensive short range hard core repulsion are taken into consideration. Internal partition functions of neutral, excited, and multiply ionized species are carefully evaluated in a statistical-mechanically consistent way. Results predicted from the present model are presented, analyzed and compared with available experimental measurements and other theoretical predictions in the literature.
Long Duration Hot Hydrogen Exposure of Nuclear Thermal Rocket Materials
NASA Technical Reports Server (NTRS)
Litchford, Ron J.; Foote, John P.; Hickman, Robert; Dobson, Chris; Clifton, Scooter
2007-01-01
An arc-heater driven hyper-thermal convective environments simulator was recently developed and commissioned for long duration hot hydrogen exposure of nuclear thermal rocket materials. This newly established non-nuclear testing capability uses a high-power, multi-gas, wall-stabilized constricted arc-heater to .produce high-temperature pressurized hydrogen flows representative of nuclear reactor core environments, excepting radiation effects, and is intended to serve as a low cost test facility for the purpose of investigating and characterizing candidate fuel/structural materials and improving associated processing/fabrication techniques. Design and engineering development efforts are fully summarized, and facility operating characteristics are reported as determined from a series of baseline performance mapping runs and long duration capability demonstration tests.
Resurrecting hot dark matter - Large-scale structure from cosmic strings and massive neutrinos
NASA Technical Reports Server (NTRS)
Scherrer, Robert J.
1988-01-01
These are the results of a numerical simulation of the formation of large-scale structure from cosmic-string loops in a universe dominated by massive neutrinos (hot dark matter). This model has several desirable features. The final matter distribution contains isolated density peaks embedded in a smooth background, producing a natural bias in the distribution of luminous matter. Because baryons can accrete onto the cosmic strings before the neutrinos, the galaxies will have baryon cores and dark neutrino halos. Galaxy formation in this model begins much earlier than in random-phase models. On large scales the distribution of clustered matter visually resembles the CfA survey, with large voids and filaments.
Red and nebulous objects in dark clouds - A survey
NASA Technical Reports Server (NTRS)
Cohen, M.
1980-01-01
A search on the NGS-PO Sky Survey photographs has revealed 150 interesting nebulous and/or red objects, mostly lying in dark clouds and not previously catalogued. Spectral classifications are presented for 55 objects. These indicate a small number of new members of the class of Herbig-Haro objects, a significant number of new T Tauri stars, and a few emission-line hot stars. It is argued that hot, high-mass stars form preferentially in the dense cores of dark clouds. The possible symbiosis of high and low mass stars is considered. A new morphology class is defined for cometary nebulae, in which a star lies on the periphery of a nebulous ring.
Bohlin, Jon; Eldholm, Vegard; Pettersson, John H O; Brynildsrud, Ola; Snipen, Lars
2017-02-10
The core genome consists of genes shared by the vast majority of a species and is therefore assumed to have been subjected to substantially stronger purifying selection than the more mobile elements of the genome, also known as the accessory genome. Here we examine intragenic base composition differences in core genomes and corresponding accessory genomes in 36 species, represented by the genomes of 731 bacterial strains, to assess the impact of selective forces on base composition in microbes. We also explore, in turn, how these results compare with findings for whole genome intragenic regions. We found that GC content in coding regions is significantly higher in core genomes than accessory genomes and whole genomes. Likewise, GC content variation within coding regions was significantly lower in core genomes than in accessory genomes and whole genomes. Relative entropy in coding regions, measured as the difference between observed and expected trinucleotide frequencies estimated from mononucleotide frequencies, was significantly higher in the core genomes than in accessory and whole genomes. Relative entropy was positively associated with coding region GC content within the accessory genomes, but not within the corresponding coding regions of core or whole genomes. The higher intragenic GC content and relative entropy, as well as the lower GC content variation, observed in the core genomes is most likely associated with selective constraints. It is unclear whether the positive association between GC content and relative entropy in the more mobile accessory genomes constitutes signatures of selection or selective neutral processes.
Song, Wenfang; Wang, Faming
2016-08-01
This study aimed to examine the effectiveness of a hybrid personal cooling system (PCS) in mitigating body heat stain while exercising in a hot environment. Eight subjects underwent two trials: PCS and CON (i.e. no cooling). All trials were conducted at an air temperature of 36 ± 0.5 °C and RH = 59 ± 5%. The key findings demonstrated that the PCS could significantly reduce the core temperature, mean skin temperature, heart rate and physiological strain index during both exercise and recovery periods (p < 0.05). Subjective perceptions were also significantly alleviated in PCS at the end of the exercise and during the recovery (p < 0.05). Besides, the PCS could also bring remarkable benefits in lowering local skin temperatures and in improving perceptual sensations in both upper and lower body during both exercise and recovery periods (p < 0.05). It was thus concluded that the hybrid PCS is effective in mitigating body heat strain while exercising in a hot environment. Practitioner Summary: In hot and humid environments, body heat dissipation through sweating is greatly restricted. Our newly developed hybrid PCS could effectively alleviate heat strain while exercising in hot environments. The findings contribute to the body of knowledge in improving the health and well-being of sportsmen while exercising in hot environments.
Symmetric cumulants as a probe of the proton substructure at LHC energies
NASA Astrophysics Data System (ADS)
Albacete, Javier L.; Petersen, Hannah; Soto-Ontoso, Alba
2018-03-01
We present a systematic study of the normalized symmetric cumulants, NSC(n,m), at the eccentricity level in proton-proton interactions at √{ s } = 13TeV within a wounded hot spot approach. We focus our attention on the influence of spatial correlations between the proton constituents, in our case gluonic hot spots, on this observable. We notice that the presence of short-range repulsive correlations between the hot spots systematically decreases the values of NSC (2 , 3) and NSC (2 , 4) in mid- to ultra-central collisions while increases them in peripheral interactions. In the case of NSC (2 , 3) we find that, as suggested by data, an anti-correlation of ε2 and ε3 in ultra-central collisions, i.e. NSC (2 , 3) < 0, is possible within the correlated scenario while it never occurs without correlations when the number of gluonic hot spots is set to three. We attribute this fact to the decisive role of correlations on enlarging the probability of interaction topologies that reduce the value of NSC (2 , 3) and, eventually, make it negative. Further, we explore the dependence of our conclusions on the number of hot spots, the values of the hot spot radius and the repulsive core distance. Our results add evidence to the idea that considering spatial correlations between the subnucleonic degrees of freedom of the proton may have a strong impact on the initial state properties of proton-proton interactions [1].
The quiescent intracluster medium in the core of the Perseus cluster.
2016-07-07
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffuse hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling--a process known as active galactic nucleus feedback. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30-60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.
The quiescent intracluster medium in the core of the Perseus cluster
Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; ...
2016-07-06
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. In this paper, we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. Finally, we infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less
The quiescent intracluster medium in the core of the Perseus cluster
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. In this paper, we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. Finally, we infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less
The quiescent intracluster medium in the core of the Perseus cluster
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie
2016-07-06
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes1 of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffusemore » hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback2, 3, 4, 5, 6. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30–60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.« less
The quiescent intracluster medium in the core of the Perseus cluster
NASA Astrophysics Data System (ADS)
Hitomi Collaboration; Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; Allen, Steven W.; Anabuki, Naohisa; Angelini, Lorella; Arnaud, Keith; Audard, Marc; Awaki, Hisamitsu; Axelsson, Magnus; Bamba, Aya; Bautz, Marshall; Blandford, Roger; Brenneman, Laura; Brown, Gregory V.; Bulbul, Esra; Cackett, Edward; Chernyakova, Maria; Chiao, Meng; Coppi, Paolo; Costantini, Elisa; de Plaa, Jelle; den Herder, Jan-Willem; Done, Chris; Dotani, Tadayasu; Ebisawa, Ken; Eckart, Megan; Enoto, Teruaki; Ezoe, Yuichiro; Fabian, Andrew C.; Ferrigno, Carlo; Foster, Adam; Fujimoto, Ryuichi; Fukazawa, Yasushi; Furuzawa, Akihiro; Galeazzi, Massimiliano; Gallo, Luigi; Gandhi, Poshak; Giustini, Margherita; Goldwurm, Andrea; Gu, Liyi; Guainazzi, Matteo; Haba, Yoshito; Hagino, Kouichi; Hamaguchi, Kenji; Harrus, Ilana; Hatsukade, Isamu; Hayashi, Katsuhiro; Hayashi, Takayuki; Hayashida, Kiyoshi; Hiraga, Junko; Hornschemeier, Ann; Hoshino, Akio; Hughes, John; Iizuka, Ryo; Inoue, Hajime; Inoue, Yoshiyuki; Ishibashi, Kazunori; Ishida, Manabu; Ishikawa, Kumi; Ishisaki, Yoshitaka; Itoh, Masayuki; Iyomoto, Naoko; Kaastra, Jelle; Kallman, Timothy; Kamae, Tuneyoshi; Kara, Erin; Kataoka, Jun; Katsuda, Satoru; Katsuta, Junichiro; Kawaharada, Madoka; Kawai, Nobuyuki; Kelley, Richard; Khangulyan, Dmitry; Kilbourne, Caroline; King, Ashley; Kitaguchi, Takao; Kitamoto, Shunji; Kitayama, Tetsu; Kohmura, Takayoshi; Kokubun, Motohide; Koyama, Shu; Koyama, Katsuji; Kretschmar, Peter; Krimm, Hans; Kubota, Aya; Kunieda, Hideyo; Laurent, Philippe; Lebrun, François; Lee, Shiu-Hang; Leutenegger, Maurice; Limousin, Olivier; Loewenstein, Michael; Long, Knox S.; Lumb, David; Madejski, Grzegorz; Maeda, Yoshitomo; Maier, Daniel; Makishima, Kazuo; Markevitch, Maxim; Matsumoto, Hironori; Matsushita, Kyoko; McCammon, Dan; McNamara, Brian; Mehdipour, Missagh; Miller, Eric; Miller, Jon; Mineshige, Shin; Mitsuda, Kazuhisa; Mitsuishi, Ikuyuki; Miyazawa, Takuya; Mizuno, Tsunefumi; Mori, Hideyuki; Mori, Koji; Moseley, Harvey; Mukai, Koji; Murakami, Hiroshi; Murakami, Toshio; Mushotzky, Richard; Nagino, Ryo; Nakagawa, Takao; Nakajima, Hiroshi; Nakamori, Takeshi; Nakano, Toshio; Nakashima, Shinya; Nakazawa, Kazuhiro; Nobukawa, Masayoshi; Noda, Hirofumi; Nomachi, Masaharu; O'Dell, Steve; Odaka, Hirokazu; Ohashi, Takaya; Ohno, Masanori; Okajima, Takashi; Ota, Naomi; Ozaki, Masanobu; Paerels, Frits; Paltani, Stephane; Parmar, Arvind; Petre, Robert; Pinto, Ciro; Pohl, Martin; Porter, F. Scott; Pottschmidt, Katja; Ramsey, Brian; Reynolds, Christopher; Russell, Helen; Safi-Harb, Samar; Saito, Shinya; Sakai, Kazuhiro; Sameshima, Hiroaki; Sato, Goro; Sato, Kosuke; Sato, Rie; Sawada, Makoto; Schartel, Norbert; Serlemitsos, Peter; Seta, Hiromi; Shidatsu, Megumi; Simionescu, Aurora; Smith, Randall; Soong, Yang; Stawarz, Lukasz; Sugawara, Yasuharu; Sugita, Satoshi; Szymkowiak, Andrew; Tajima, Hiroyasu; Takahashi, Hiromitsu; Takahashi, Tadayuki; Takeda, Shin'Ichiro; Takei, Yoh; Tamagawa, Toru; Tamura, Keisuke; Tamura, Takayuki; Tanaka, Takaaki; Tanaka, Yasuo; Tanaka, Yasuyuki; Tashiro, Makoto; Tawara, Yuzuru; Terada, Yukikatsu; Terashima, Yuichi; Tombesi, Francesco; Tomida, Hiroshi; Tsuboi, Yohko; Tsujimoto, Masahiro; Tsunemi, Hiroshi; Tsuru, Takeshi; Uchida, Hiroyuki; Uchiyama, Hideki; Uchiyama, Yasunobu; Ueda, Shutaro; Ueda, Yoshihiro; Ueno, Shiro; Uno, Shin'Ichiro; Urry, Meg; Ursino, Eugenio; de Vries, Cor; Watanabe, Shin; Werner, Norbert; Wik, Daniel; Wilkins, Dan; Williams, Brian; Yamada, Shinya; Yamaguchi, Hiroya; Yamaoka, Kazutaka; Yamasaki, Noriko Y.; Yamauchi, Makoto; Yamauchi, Shigeo; Yaqoob, Tahir; Yatsu, Yoichi; Yonetoku, Daisuke; Yoshida, Atsumasa; Yuasa, Takayuki; Zhuravleva, Irina; Zoghbi, Abderahmen
2016-07-01
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes of cosmological parameters and many astrophysical processes. However, knowledge of the dynamics of the pervasive hot gas, the mass of which is much larger than the combined mass of all the stars in the cluster, is lacking. Such knowledge would enable insights into the injection of mechanical energy by the central supermassive black hole and the use of hydrostatic equilibrium for determining cluster masses. X-rays from the core of the Perseus cluster are emitted by the 50-million-kelvin diffuse hot plasma filling its gravitational potential well. The active galactic nucleus of the central galaxy NGC 1275 is pumping jetted energy into the surrounding intracluster medium, creating buoyant bubbles filled with relativistic plasma. These bubbles probably induce motions in the intracluster medium and heat the inner gas, preventing runaway radiative cooling—a process known as active galactic nucleus feedback. Here we report X-ray observations of the core of the Perseus cluster, which reveal a remarkably quiescent atmosphere in which the gas has a line-of-sight velocity dispersion of 164 ± 10 kilometres per second in the region 30-60 kiloparsecs from the central nucleus. A gradient in the line-of-sight velocity of 150 ± 70 kilometres per second is found across the 60-kiloparsec image of the cluster core. Turbulent pressure support in the gas is four per cent of the thermodynamic pressure, with large-scale shear at most doubling this estimate. We infer that a total cluster mass determined from hydrostatic equilibrium in a central region would require little correction for turbulent pressure.
Post-irradiation-examination of irradiated fuel outside the hot cell
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dawn E. Janney; Adam B. Robinson; Thomas P. O'Holleran
Because of their high radioactivity, irradiated fuels are commonly examined in a hot cell. However, the Idaho National Laboratory (INL) has recently investigated irradiated U-Mo-Al metallic fuel from the Reduced Enrichment for Research and Test Reactors (RERTR) project using a conventional unshielded scanning electron microscope outside a hot cell. This examination was possible because of a two-step sample-preparation approach in which a small volume of fuel was isolated in a hot cell and shielding was introduced during later stages of sample preparation. The resulting sample contained numerous sample-preparation artifacts but allowed analysis of microstructures from selected areas.
Transition to turbulence and noise radiation in heated coaxial jet flows
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gloor, Michael, E-mail: gloor@ifd.mavt.ethz.ch; Bühler, Stefan; Kleiser, Leonhard
2016-04-15
Laminar-turbulent transition and noise radiation of a parametrized set of subsonic coaxial jet flows with a hot primary (core) stream are investigated numerically by Large-Eddy Simulation (LES) and direct noise computation. This study extends our previous research on local linear stability of heated coaxial jet flows by analyzing the nonlinear evolution of initially laminar flows disturbed by a superposition of small-amplitude unstable eigenmodes. First, a baseline configuration is studied to shed light on the flow dynamics of coaxial jet flows. Subsequently, LESs are performed for a range of Mach and Reynolds numbers to systematically analyze the influences of the temperaturemore » and the velocity ratios between the primary and the secondary (bypass) stream. The results provide a basis for a detailed analysis of fundamental flow-acoustic phenomena in the considered heated coaxial jet flows. Increasing the primary-jet temperature leads to an increase of fluctuation levels and to an amplification of far-field noise, especially at low frequencies. Strong mixing between the cold bypass stream and the hot primary stream as well as the intermittent character of the flow field at the end of the potential core lead to a pronounced noise radiation at an aft angle of approximately 35{sup ∘}. The velocity ratio strongly affects the shear-layer development and therefore also the noise generation mechanisms. Increasing the secondary-stream velocity amplifies the dominance of outer shear-layer perturbations while the disturbance growth rates in the inner shear layer decrease. Already for r{sub mic} > 40R{sub 1}, where r{sub mic} is the distance from the end of the potential core and R{sub 1} is the core-jet radius, a perfect 1/r{sub mic} decay of the sound pressure amplitudes is observed. The potential-core length increases for higher secondary-stream velocities which leads to a shift of the center of the dominant acoustic radiation in the downstream direction.« less
Firefighter feedback during active cooling: a useful tool for heat stress management?
Savage, Robbie J; Lord, Cara; Larsen, Brianna L; Knight, Teagan L; Langridge, Peter D; Aisbett, Brad
2014-12-01
Monitoring an individual's thermic state in the workplace requires reliable feedback of their core temperature. However, core temperature measurement technology is expensive, invasive and often impractical in operational environments, warranting investigation of surrogate measures which could be used to predict core temperature. This study examines an alternative measure of an individual's thermic state, thermal sensation, which presents a more manageable and practical solution for Australian firefighters operating on the fireground. Across three environmental conditions (cold, warm, hot & humid), 49 Australian volunteer firefighters performed a 20-min fire suppression activity, immediately followed by 20 min of active cooling using hand and forearm immersion techniques. Core temperature (Tc) and thermal sensation (TS) were measured across the rehabilitation period at five minute intervals. Despite the decline in Tc and TS throughout the rehabilitation period, there was little similarity in the magnitude or rate of decline between each measure in any of the ambient conditions. Moderate to strong correlations existed between Tc and TS in the cool (0.41, p<0.05) and hot & humid (0.57, p<0.05) conditions, however this was resultant in strong correlation during the earlier stages of rehabilitation (first five minutes), which were not evident in the latter stages. Linear regression revealed TS to be a poor predictor of Tc in all conditions (SEE=0.45-0.54°C) with a strong trend for TS to over-predict Tc (77-80% of the time). There is minimal evidence to suggest that ratings of thermal sensation, which represent a psychophysical assessment of an individual's thermal comfort, are an accurate reflection of the response of an individual's core temperature. Ratings of thermal sensation can be highly variable amongst individuals, likely moderated by local skin temperature. In account of these findings, fire managers require a more reliable source of information to guide decisions of heat stress management. Copyright © 2014 Elsevier Ltd. All rights reserved.
Thermal stress in North Western Australian iron ore mining staff.
Peiffer, Jeremiah J; Abbiss, Chris R
2013-05-01
Demand for Australian mined iron ore has increased employment within this sector, thus exposing increased numbers of workers to the harsh Australian climate. This study examined the influence of hot (>30°C wet bulb globe temperature) environmental temperatures, consistent with working in North Western Australia, on iron ore mining staff. Core temperature, hydration status, perceived exertion, mood, and fatigue state were measured in 77 participants at three time points (pre-, mid-, and post-shift) during a normal 12-h shift at an open-cut iron ore mining/processing site (n = 31; Site1) and an iron ore processing/shipping site (n = 46; Site2). A significant effect for time was observed for core temperature with greater mean core temperatures measured mid-shift (37.5±0.4°C) and post-shift (37.6±0.3°C) compared with pre-shift values (37.0±0.5°C). All mean core temperature measures were lower than ISO7933 thresholds (38°C) for thermal safety. Mean hydration measures [urine-specific gravity (USG)] were greater at Site1 (1.029±0.006) compared with those at Site2 (1.021±0.007). Furthermore, both pre- and post-shift measures from Site1 and the post-shift measures from Site2 were greater than the threshold for dehydration (USG = 1.020). No differences were observed for mood or perceived exertion over time; however, measures of fatigue state were greater post-shift compared with pre- and mid-shift values for both sites. Our findings indicate that the majority of mine workers in North Western Australia are able to regulate work rate in hot environments to maintain core temperatures below ISO safety guidelines; however, 22% of workers reached or exceeded the safety guidelines, warranting further investigation. Furthermore, hydration practices, especially when off-work, appear inadequate and could endanger health and safety.
High-mass Star Formation through Filamentary Collapse and Clump-fed Accretion in G22
NASA Astrophysics Data System (ADS)
Yuan, Jinghua; Li, Jin-Zeng; Wu, Yuefang; Ellingsen, Simon P.; Henkel, Christian; Wang, Ke; Liu, Tie; Liu, Hong-Li; Zavagno, Annie; Ren, Zhiyuan; Huang, Ya-Fang
2018-01-01
How mass is accumulated from cloud-scale down to individual stars is a key open question in understanding high-mass star formation. Here, we present the mass accumulation process in a hub-filament cloud G22 that is composed of four supercritical filaments. Velocity gradients detected along three filaments indicate that they are collapsing with a total mass infall rate of about 440 M ⊙ Myr‑1, suggesting the hub mass would be doubled in six free-fall times, adding up to ∼2 Myr. A fraction of the masses in the central clumps C1 and C2 can be accounted for through large-scale filamentary collapse. Ubiquitous blue profiles in HCO+ (3–2) and 13CO (3–2) spectra suggest a clump-scale collapse scenario in the most massive and densest clump C1. The estimated infall velocity and mass infall rate are 0.31 km s‑1 and 7.2 × 10‑4 M ⊙ yr‑1, respectively. In clump C1, a hot molecular core (SMA1) is revealed by the Submillimeter Array observations and an outflow-driving high-mass protostar is located at the center of SMA1. The mass of the protostar is estimated to be 11–15 M ⊙ and it is still growing with an accretion rate of 7 × 10‑5 M ⊙ yr‑1. The coexistent infall in filaments, clump C1, and the central hot core in G22 suggests that pre-assembled mass reservoirs (i.e., high-mass starless cores) may not be required to form high-mass stars. In the course of high-mass star formation, the central protostar, the core, and the clump can simultaneously grow in mass via core-fed/disk accretion, clump-fed accretion, and filamentary/cloud collapse.
Multichannel temperature controller for hot air solar house
NASA Technical Reports Server (NTRS)
Currie, J. R.
1979-01-01
This paper describes an electronic controller that is optimized to operate a hot air solar system. Thermal information is obtained from copper constantan thermocouples and a wall-type thermostat. The signals from the thermocouples are processed through a single amplifier using a multiplexing scheme. The multiplexing reduces the component count and automatically calibrates the thermocouple amplifier. The processed signals connect to some simple logic that selects one of the four operating modes. This simple, inexpensive, and reliable scheme is well suited to control hot air solar systems.
NASA Astrophysics Data System (ADS)
Song, Woo-Seuk; Lee, Hye-Seung; Lee, Ju Chul; Jang, Dong Seon; Choi, Yoonyoung; Choi, Moongoo; Yang, Heesun
2013-06-01
High-quality, Cd-free InP quantum dots (QDs) have been conventionally synthesized by exclusively selecting tris(trimethylsilyl)phosphine (P(TMS)3) as a phosphorus (P) precursor, which is problematic from the standpoint of green and economic chemistry. Thus, other synthetic chemistries adopting alternative P sources to P(TMS)3 have been introduced, however, they could not guarantee the production of satisfactorily fluorescence-efficient, color-pure InP QDs. In this study, the unprecedented controlled synthesis of a series of band-gap-tuned InP QDs is demonstrated through a hot-injection of a far safer and cheaper tris(dimethylamino)phosphine in the presence of a key coordinating solvent of oleylamine that enables successful QD nucleation/growth. Effects of the co-existence of Zn additive, the core growth temperature, and the amount of P source injected on the growth behaviors of InP QD are investigated. After ZnS overcoating by a successive injection of 1-dodecanethiol only, high-fluorescence-quality, green-to-red color emission-tunable core/shell QDs of InP/ZnS are obtained. The fluorescent characteristics of different color-emitting QDs desirably exhibit little fluctuations in quantum yield and emission bandwidth, specifically ranging 51-53 % and 60-64 nm, respectively. Lastly, the utility of the introduction of a secondary shelling process in rendering the QDs are more bright, photostable is also proved.
Laboratory evaluation of thermal protective clothing performance upon hot liquid splash.
Gholamreza, Farzan; Song, Guowen
2013-07-01
This study provides an understanding of heat and mass transfer through materials exposed to hot liquid splash, a relatively unexplored hazard in the safety clothing industry. Selected fabrics and layered systems were exposed to three hot liquids to study the effects of hot liquids and configuration. To explore the energy transfer mechanisms, a modified apparatus (based on ASTM F 2701-08) was developed to assess the protection performance provided by a fabric when exposed to a hot liquid. The modified test method allows measurement of the energy absorbed by the sensor, and with the use of a skin model, the time required to produce a second-degree burn injury was predicted. The preliminary testing demonstrated that mass transfer of the hot liquid through the fabric is the main factor contributing to burn injury. Key factors that determine the level of protection that a fabric system provides are summarized.
Plasmonic hot electron transport drives nano-localized chemistry
Cortés, Emiliano; Xie, Wei; Cambiasso, Javier; Jermyn, Adam S.; Sundararaman, Ravishankar; Narang, Prineha; Schlücker, Sebastian; Maier, Stefan A.
2017-01-01
Nanoscale localization of electromagnetic fields near metallic nanostructures underpins the fundamentals and applications of plasmonics. The unavoidable energy loss from plasmon decay, initially seen as a detriment, has now expanded the scope of plasmonic applications to exploit the generated hot carriers. However, quantitative understanding of the spatial localization of these hot carriers, akin to electromagnetic near-field maps, has been elusive. Here we spatially map hot-electron-driven reduction chemistry with 15 nm resolution as a function of time and electromagnetic field polarization for different plasmonic nanostructures. We combine experiments employing a six-electron photo-recycling process that modify the terminal group of a self-assembled monolayer on plasmonic silver nanoantennas, with theoretical predictions from first-principles calculations of non-equilibrium hot-carrier transport in these systems. The resulting localization of reactive regions, determined by hot-carrier transport from high-field regions, paves the way for improving efficiency in hot-carrier extraction science and nanoscale regio-selective surface chemistry. PMID:28348402
Dinkins, Jonathan B; Smith, Kurt T; Beck, Jeffrey L; Kirol, Christopher P; Pratt, Aaron C; Conover, Michael R
2016-01-01
The purpose of our study was to identify microhabitat characteristics of greater sage-grouse (Centrocercus urophasianus) nest site selection and survival to determine the quality of sage-grouse habitat in 5 regions of central and southwest Wyoming associated with Wyoming's Core Area Policy. Wyoming's Core Area Policy was enacted in 2008 to reduce human disturbance near the greatest densities of sage-grouse. Our analyses aimed to assess sage-grouse nest selection and success at multiple micro-spatial scales. We obtained microhabitat data from 928 sage-grouse nest locations and 819 random microhabitat locations from 2008-2014. Nest success was estimated from 924 nests with survival data. Sage-grouse selected nests with greater sagebrush cover and height, visual obstruction, and number of small gaps between shrubs (gap size ≥0.5 m and <1.0 m), while selecting for less bare ground and rock. With the exception of more small gaps between shrubs, we did not find any differences in availability of these microhabitat characteristics between locations within and outside of Core Areas. In addition, we found little supporting evidence that sage-grouse were selecting different nest sites in Core Areas relative to areas outside of Core. The Kaplan-Meier nest success estimate for a 27-day incubation period was 42.0% (95% CI: 38.4-45.9%). Risk of nest failure was negatively associated with greater rock and more medium-sized gaps between shrubs (gap size ≥2.0 m and <3.0 m). Within our study areas, Wyoming's Core Areas did not have differing microhabitat quality compared to outside of Core Areas. The close proximity of our locations within and outside of Core Areas likely explained our lack of finding differences in microhabitat quality among locations within these landscapes. However, the Core Area Policy is most likely to conserve high quality habitat at larger spatial scales, which over decades may have cascading effects on microhabitat quality available between areas within and outside of Core Areas.
Bargar, K.E.
1991-01-01
The Platanares geothermal area in western Honduras consists of more than 100 hot springs that issue from numerous hot-spring groups along the banks or within the streambed of the Quebrada de Agua Caliente (brook of hot water). Evaluation of this geothermal area included drilling a 650-m deep PLTG-1 drill hole which penetrated a surface mantling of stream terrace deposits, about 550 m of Tertiary andesitic lava flows, and Cretaceous to lower Tertiary sedimentary rocks in the lower 90 m of the drill core. Fractures and cavities in the drill core are partly to completely filled by hydrothermal minerals that include quartz, kaolinite, mixed-layer illite-smectite, barite, fluorite, chlorite, calcite, laumontite, biotite, hematite, marcasite, pyrite, arsenopyrite, stibnite, and sphalerite; the most common open-space fillings are calcite and quartz. Biotite from 138.9-m depth, dated at 37.41 Ma by replicate 40Ar/39 Ar analyses using a continuous laser system, is the earliest hydrothermal mineral deposited in the PLTG-1 drill core. This mid-Tertiary age indicates that at least some of the hydrothermal alteration encountered in the PLTG-1 drill core occured in the distant past and is unrelated to the present geothermal system. Furthermore, homogenization temperatures (Th) and melting-point temperatures (Tm) for fluid inclusions in two of the later-formed hydrothermal minerals, calcite and barite, suggest that the temperatures and concentration of dissolved solids of the fluids present at the time these fluid inclusions formed were very different from the present temperatures and fluid chemistry measured in the drill hole. Liquid-rich secondary fluid inclusions in barite and caicite from drill hole PLTG-1 have Th values that range from about 20??C less than the present measured temperature curve at 590.1-m depth to as much as 90??C higher than the temperature curve at 46.75-m depth. Many of the barite Th measurements (ranging between 114?? and 265??C) plot above the reference surface boiling-point curve for pure water assuming hydrostatic conditions; however, the absence of evidence for boiling in the fluid inclusions indicates that at the time the minerals formed, the ground surface must have been at least 80 m higher than at present and underwent stream erosion to the current elevation. Near-surface mixed-layer illite-smectite is closely associated with barite and appears to have formed at about the same temperature range (about 120?? to 200??C) as the fluid-inclusion Th values for barite. Fluid-inclusion Th values for calcite range between about 136?? and 213??C. Several of the calcite Th values are significantly lower than the present measured temperature curve. The melting-point temperatures (Tm) of fluid-inclusion ice yield calculated salinities, ranging from near zero to as much as 5.4 wt. % NaCl equivalent, which suggest that much of the barite and calcite precipitated from fluids of significantly greater salinity than the present low salinity Platanares hot-spring water or water produced from the drill hole. ?? 1991.
Development of lightweight graphite/polyimide honeycomb. Phase 1: Materials selection
NASA Technical Reports Server (NTRS)
Poesch, J. G.
1971-01-01
The materials selected for the production of extremely lightweight honeycomb sandwich panels are discussed. The resin selected for the first core and face sheet fabrication was Monsanto RS6234 polyimide. The fiber selected for core manufacture was Hercules HT-S, and for face sheets, Hercules HM-S; these selections are discussed.
NASA Technical Reports Server (NTRS)
Nakazawa, S.
1987-01-01
This Annual Status Report presents the results of work performed during the third year of the 3-D Inelastic Analysis Methods for Hot Section Components program (NASA Contract NAS3-23697). The objective of the program is to produce a series of new computer codes that permit more accurate and efficient three-dimensional analysis of selected hot section components, i.e., combustor liners, turbine blades, and turbine vanes. The computer codes embody a progression of mathematical models and are streamlined to take advantage of geometrical features, loading conditions, and forms of material response that distinguish each group of selected components. This report is presented in two volumes. Volume 1 describes effort performed under Task 4B, Special Finite Element Special Function Models, while Volume 2 concentrates on Task 4C, Advanced Special Functions Models.
Eddington-limited Accretion in z ∼ 2 WISE-selected Hot, Dust-obscured Galaxies
NASA Astrophysics Data System (ADS)
Wu, Jingwen; Jun, Hyunsung D.; Assef, Roberto J.; Tsai, Chao-Wei; Wright, Edward L.; Eisenhardt, Peter R. M.; Blain, Andrew; Stern, Daniel; Díaz-Santos, Tanio; Denney, Kelly D.; Hayden, Brian T.; Perlmutter, Saul; Aldering, Greg; Boone, Kyle; Fagrelius, Parker
2018-01-01
Hot, dust-obscured galaxies, or “Hot DOGs,” are a rare, dusty, hyperluminous galaxy population discovered by the WISE mission. Predominantly at redshifts 2–3, they include the most luminous known galaxies in the universe. Their high luminosities likely come from accretion onto highly obscured supermassive black holes (SMBHs). We have conducted a pilot survey to measure the SMBH masses of five z∼ 2 Hot DOGs via broad Hα emission lines, using Keck/MOSFIRE and Gemini/FLAMINGOS-2. We detect broad Hα emission in all five Hot DOGs. We find substantial corresponding SMBH masses for these Hot DOGs (∼ {10}9 {M}ȯ ), and their derived Eddington ratios are close to unity. These z∼ 2 Hot DOGs are the most luminous active galactic nuclei for their BH masses, suggesting that they are accreting at the maximum rates for their BHs. A similar property is found for known z∼ 6 quasars. Our results are consistent with scenarios in which Hot DOGs represent a transitional, high-accretion phase between obscured and unobscured quasars. Hot DOGs may mark a special evolutionary stage before the red quasar and optical quasar phases, and they may be present at other cosmic epochs.
Hot-start Giant Planets Form with Radiative Interiors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berardo, David; Cumming, Andrew, E-mail: david.berardo@mcgill.ca, E-mail: andrew.cumming@mcgill.ca
In the hot-start core accretion formation model for gas giants, the interior of a planet is usually assumed to be fully convective. By calculating the detailed internal evolution of a planet assuming hot-start outer boundary conditions, we show that such a planet will in fact form with a radially increasing internal entropy profile, so that its interior will be radiative instead of convective. For a hot outer boundary, there is a minimum value for the entropy of the internal adiabat S {sub min} below which the accreting envelope does not match smoothly onto the interior, but instead deposits high entropymore » material onto the growing interior. One implication of this would be to at least temporarily halt the mixing of heavy elements within the planet, which are deposited by planetesimals accreted during formation. The compositional gradient this would impose could subsequently disrupt convection during post-accretion cooling, which would alter the observed cooling curve of the planet. However, even with a homogeneous composition, for which convection develops as the planet cools, the difference in cooling timescale will change the inferred mass of directly imaged gas giants.« less
Hot subdwarfs in (eclipsing) binaries with brown dwarf or low-mass main-sequence companions
NASA Astrophysics Data System (ADS)
Schaffenroth, Veronika; Geier, Stephan; Heber, Uli
2014-09-01
The formation of hot subdwarf stars (sdBs), which are core helium-burning stars located on the extended horizontal branch, is not yet understood. Many of the known hot subdwarf stars reside in close binary systems with short orbital periods of between a few hours and a few days, with either M-star or white-dwarf companions. Common-envelope ejection is the most probable formation channel. Among these, eclipsing systems are of special importance because it is possible to constrain the parameters of both components tightly by combining spectroscopic and light-curve analyses. They are called HW Virginis systems. Soker (1998) proposed that planetary or brown-dwarf companions could cause the mass loss necessary to form an sdB. Substellar objects with masses greater than >10 M_J were predicted to survive the common-envelope phase and end up in a close orbit around the stellar remnant, while planets with lower masses would entirely evaporate. This raises the question if planets can affect stellar evolution. Here we report on newly discovered eclipsing or not eclipsing hot subdwarf binaries with brown-dwarf or low-mass main-sequence companions and their spectral and photometric analysis to determine the fundamental parameters of both components.
Plasmonic Heterodimers with Binding Site-Dependent Hot Spot for Surface-Enhanced Raman Scattering.
Tian, Yuanyuan; Shuai, Zhenhua; Shen, Jingjing; Zhang, Lei; Chen, Shufen; Song, Chunyuan; Zhao, Baomin; Fan, Quli; Wang, Lianhui
2018-06-01
A novel plasmonic heterodimer nanostructure with a controllable self-assembled hot spot is fabricated by the conjugation of individual Au@Ag core-shell nanocubes (Au@Ag NCs) and varisized gold nanospheres (GNSs) via the biotin-streptavidin interaction from the ensemble to the single-assembly level. Due to their featured configurations, three types of heterogeneous nanostructures referred to as Vertice, Vicinity, and Middle are proposed and a single hot spot forms between the nanocube and nanosphere, which exhibits distinct diversity in surface plasmon resonance effect. Herein, the calculated surface-enhanced Raman scattering enhancement factors of the three types of heterodimers show a narrow distribution and can be tuned in orders of magnitude by controlling the size of GNSs onto individual Au@Ag NCs. Particularly, the Vertice heterodimer with unique configuration can provide extraordinary enhancement of the electric field for the single hot spot region due to the collaborative interaction of lightning rod effect and interparticle plasmon coupling effect. This established relationship between the architecture and the corresponding optical properties of the heterodimers provides the basis for creating controllable platforms which can be exploited in the applications of plasmonic devices, electronics, and biodetection. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
NASA Astrophysics Data System (ADS)
Vollmer, R.; Palm, C.
2017-09-01
The increasing number of hot stamped parts in the automotive industry is challenging different process areas. This paper presents a method how to improve the production rates over the whole life cycle of a hot forming part. In the core element of a hot forming line, the hydraulic press, mainly two processing steps are performed. Forming and quenching of the sheet metal part. In addition to the forming operation, it is inevitable to optimize the quenching condition in the bottom dead centre in order to reach a fully martensitic structure and tight geometrical tolerances of the part. Deviations in the blank thickness, tool wear, polishing of classical tools impair the quenching condition and therefore the part quality over the time. A new press and tool design has been developed to counter this effect by providing homogenous contact pressure over the whole die. Especially with a multi cavity tool, the new method is advantageous. Test series have shown that the new tool and press concept can produce parts with a blank thickness of 1.0 mm within 8.0 s cycle time. The so called PCH flex principle makes it possible to produce such high output rates under reliable conditions.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-30
... Steel Flat Products From India: Rescission of Antidumping Duty Administrative Review AGENCY: Import... certain hot- rolled carbon steel flat products from India for the period December 1, 2010, through... Products from India: Customs and Border Protection Data for Selection of Respondents for Individual Review...
Hot-spot heating susceptibility due to reverse bias operating conditions
NASA Technical Reports Server (NTRS)
Gonzalez, C. C.
1985-01-01
Because of field experience (indicating that cell and module degradation could occur as a result of hot spot heating), a laboratory test was developed at JPL to determine hot spot susceptibility of modules. The initial hot spot testing work at JPL formed a foundation for the test development. Test parameters are selected as follows. For high shunt resistance cells, the applied back bias test current is set equal to the test cell current at maximum power. For low shunt resistance cells, the test current is set equal to the cell short circuit current. The shadow level is selected to conform to that which would lead to maximum back bias voltage under the appropriate test current level. The test voltage is determined by the bypass diode frequency. The test conditions are meant to simulate the thermal boundary conditions for 100 mW/sq cm, 40C ambient environment. The test lasts 100 hours. A key assumption made during the development of the test is that no current imbalance results from the connecting of multiparallel cell strings. Therefore, the test as originally developed was applicable for single string case only.
The Overdense Environments of WISE-selected, ultra-luminous, high-redshift AGN in the submillimetre
NASA Astrophysics Data System (ADS)
Jones, Suzy F.
2017-11-01
The environments around WISE-selected hot dust obscured galaxies (Hot DOGs) and WISE/radio-selected active galactic nuclei (AGNs) at average redshifts of z = 2.7 and z = 1.7, respectively, were found to have overdensities of companion submillimetre-selected sources. The overdensities were of ˜ 2 - 3 and ˜ 5 - 6 , respectively, compared with blank field submm surveys. The space densities in both samples were found to be overdense compared to normal star-forming galaxies and submillimetre galaxies (SMGs). All of the companion sources have consistent mid-IR colours and mid-IR to submm ratios to SMGs. Monte Carlo simulations show no angular correlation, which could indicate protoclusters on scales larger than the SCUBA-2 1.5 arcmin scale maps. WISE-selected AGNs appear to be good indicators of overdense areas of active galaxies at high redshift.
Multiprocessor switch with selective pairing
Gara, Alan; Gschwind, Michael K; Salapura, Valentina
2014-03-11
System, method and computer program product for a multiprocessing system to offer selective pairing of processor cores for increased processing reliability. A selective pairing facility is provided that selectively connects, i.e., pairs, multiple microprocessor or processor cores to provide one highly reliable thread (or thread group). Each paired microprocessor or processor cores that provide one highly reliable thread for high-reliability connect with a system components such as a memory "nest" (or memory hierarchy), an optional system controller, and optional interrupt controller, optional I/O or peripheral devices, etc. The memory nest is attached to a selective pairing facility via a switch or a bus
Influence of environmental temperature on 40 km cycling time-trial performance.
Peiffer, Jeremiah J; Abbiss, Chris R
2011-06-01
The purpose of this study was to examine the effect of environmental temperature on variability in power output, self-selected pacing strategies, and performance during a prolonged cycling time trial. Nine trained male cyclists randomly completed four 40 km cycling time trials in an environmental chamber at 17°C, 22°C, 27°C, and 32°C (40% RH). During the time trials, heart rate, core body temperature, and power output were recorded. The variability in power output was assessed with the use of exposure variation analysis. Mean 40 km power output was significantly lower during 32°C (309 ± 35 W) compared with 17°C (329 ± 31 W), 22°C (324 ± 34 W), and 27°C (322 ± 32 W). In addition, greater variability in power production was observed at 32°C compared with 17°C, as evidenced by a lower (P = .03) standard deviation of the exposure variation matrix (2.9 ± 0.5 vs 3.5 ± 0.4 units, respectively). Core temperature was greater (P < .05) at 32°C compared with 17°C and 22°C from 30 to 40 km, and the rate of rise in core temperature throughout the 40 km time trial was greater (P < .05) at 32°C (0.06 ± 0.04°C·km-1) compared with 17°C (0.05 ± 0.05°C·km-1). This study showed that time-trial performance is reduced under hot environmental conditions, and is associated with a shift in the composition of power output. These finding provide insight into the control of pacing strategies during exercise in the heat.
Development of sustained and dual drug release co-extrusion formulations for individual dosing.
Laukamp, Eva Julia; Vynckier, An-Katrien; Voorspoels, Jody; Thommes, Markus; Breitkreutz, Joerg
2015-01-01
In personalized medicine and patient-centered medical treatment individual dosing of medicines is crucial. The Solid Dosage Pen (SDP) allows for an individual dosing of solid drug carriers by cutting them into tablet-like slices. The aim of the present study was the development of sustained release and dual release formulations with carbamazepine (CBZ) via hot-melt co-extrusion for the use in the SDP. The selection of appropriate coat- and core-formulations was performed by adapting the mechanical properties (like tensile strength and E-modulus) for example. By using different excipients (polyethyleneglycols, poloxamers, white wax, stearic acid, and carnauba wax) and drug loadings (30-50%) tailored dissolution kinetics was achieved showing cube root or zero order release mechanisms. Besides a biphasic drug release, the dose-dependent dissolution characteristics of sustained release formulations were minimized by a co-extruded wax-coated formulation. The dissolution profiles of the co-extrudates were confirmed during short term stability study (six months at 21.0 ± 0.2 °C, 45%r.h.). Due to a good layer adhesion of core and coat and adequate mechanical properties (maximum cutting force of 35.8 ± 2.0 N and 26.4 ± 2.8 N and E-modulus of 118.1 ± 8.4 and 33.9 ± 4.5 MPa for the dual drug release and the wax-coated co-extrudates, respectively) cutting off doses via the SDP was precise. While differences of the process parameters (like the barrel temperature) between the core- and the coat-layer resulted in unsatisfying content uniformities for the wax-coated co-extrudates, the content uniformity of the dual drug release co-extrudates was found to be in compliance with pharmacopoeial specification. Copyright © 2015 Elsevier B.V. All rights reserved.
Acute acetaminophen (paracetamol) ingestion improves time to exhaustion during exercise in the heat.
Mauger, Alexis R; Taylor, Lee; Harding, Christopher; Wright, Benjamin; Foster, Josh; Castle, Paul C
2014-01-01
Acetaminophen (paracetamol) is a commonly used over-the-counter analgesic and antipyretic and has previously been shown to improve exercise performance through a reduction in perceived pain. This study sought to establish whether its antipyretic action may also improve exercise capacity in the heat by moderating the increase in core temperature. On separate days, 11 recreationally active participants completed two experimental time-to-exhaustion trials on a cycle ergometer in hot conditions (30°C, 50% relative humidity) after ingesting a placebo control or an oral dose of acetaminophen in a randomized, double-blind design. Following acetaminophen ingestion, participants cycled for a significantly longer period of time (acetaminophen, 23 ± 15 min versus placebo, 19 ± 13 min; P = 0.005; 95% confidence interval = 90-379 s), and this was accompanied by significantly lower core (-0.15°C), skin (-0.47°C) and body temperatures (0.19°C; P < 0.05). In the acetaminophen condition, participants also reported significantly lower ratings of thermal sensation (-0.39; P = 0.015), but no significant change in heart rate was observed (P > 0.05). This is the first study to demonstrate that an acute dose of acetaminophen can improve cycling capacity in hot conditions, and that this may be due to the observed reduction in core, skin and body temperature and the subjective perception of thermal comfort. These findings suggest that acetaminophen may reduce the thermoregulatory strain elicited from exercise, thus improving time to exhaustion.
Method for manufacturing magnetohydrodynamic electrodes
Killpatrick, D.H.; Thresh, H.R.
1980-06-24
A method of manufacturing electrodes for use in a magnetohydrodynamic (MHD) generator is described comprising the steps of preparing a billet having a core of a first metal, a tubular sleeve of a second metal, and an outer sheath of an extrusile metal; evacuating the space between the parts of the assembled billet; extruding the billet; and removing the outer jacket. The extruded bar may be made into electrodes by cutting and bending to the shape required for an MHD channel frame. The method forms a bond between the first metal of the core and the second metal of the sleeve strong enough to withstand a hot and corrosive environment.
Correlation of reaction sites during the chlorine extraction by hydrogen atom from Cl /Si(100)-2×1
NASA Astrophysics Data System (ADS)
Hsieh, Ming-Feng; Chung, Jen-Yang; Lin, Deng-Sung; Tsay, Shiow-Fon
2007-07-01
The Cl abstraction by gas-phase H atoms from a Cl-terminated Si(100) surface was investigated by scanning tunneling microscopy (STM), high-resolution core level photoemission spectroscopy, and computer simulation. The core level measurements indicate that some additional reactions occur besides the removal of Cl. The STM images show that the Cl-extracted sites disperse randomly in the initial phase of the reaction, but form small clusters as more Cl is removed, indicating a correlation between Cl-extracted sites. These results suggest that the hot-atom process may occur during the atom-adatom collision.
NASA Astrophysics Data System (ADS)
Leite, Ivo T.; Turtaev, Sergey; Jiang, Xin; Šiler, Martin; Cuschieri, Alfred; Russell, Philip St. J.; Čižmár, Tomáš
2018-01-01
Holographic optical tweezers (HOT) hold great promise for many applications in biophotonics, allowing the creation and measurement of minuscule forces on biomolecules, molecular motors and cells. Geometries used in HOT currently rely on bulk optics, and their exploitation in vivo is compromised by the optically turbid nature of tissues. We present an alternative HOT approach in which multiple three-dimensional (3D) traps are introduced through a high-numerical-aperture multimode optical fibre, thus enabling an equally versatile means of manipulation through channels having cross-section comparable to the size of a single cell. Our work demonstrates real-time manipulation of 3D arrangements of micro-objects, as well as manipulation inside otherwise inaccessible cavities. We show that the traps can be formed over fibre lengths exceeding 100 mm and positioned with nanometric resolution. The results provide the basis for holographic manipulation and other high-numerical-aperture techniques, including advanced microscopy, through single-core-fibre endoscopes deep inside living tissues and other complex environments.
X-ray penumbral imaging diagnostic developments at the National Ignition Facility
NASA Astrophysics Data System (ADS)
Bachmann, B.; Abu-Shawareb, H.; Alexander, N.; Ayers, J.; Bailey, C. G.; Bell, P.; Benedetti, L. R.; Bradley, D.; Collins, G.; Divol, L.; Döppner, T.; Felker, S.; Field, J.; Forsman, A.; Galbraith, J. D.; Hardy, C. M.; Hilsabeck, T.; Izumi, N.; Jarrot, C.; Kilkenny, J.; Kramer, S.; Landen, O. L.; Ma, T.; MacPhee, A.; Masters, N.; Nagel, S. R.; Pak, A.; Patel, P.; Pickworth, L. A.; Ralph, J. E.; Reed, C.; Rygg, J. R.; Thorn, D. B.
2017-08-01
X-ray penumbral imaging has been successfully fielded on a variety of inertial confinement fusion (ICF) capsule implosion experiments on the National Ignition Facility (NIF). We have demonstrated sub-5 μm resolution imaging of stagnated plasma cores (hot spots) at x-ray energies from 6 to 30 keV. These measurements are crucial for improving our understanding of the hot deuterium-tritium fuel assembly, which can be affected by various mechanisms, including complex 3-D perturbations caused by the support tent, fill tube or capsule surface roughness. Here we present the progress on several approaches to improve x-ray penumbral imaging experiments on the NIF. We will discuss experimental setups that include penumbral imaging from multiple lines-of-sight, target mounted penumbral apertures and variably filtered penumbral images. Such setups will improve the signal-to-noise ratio and the spatial imaging resolution, with the goal of enabling spatially resolved measurements of the hot spot electron temperature and material mix in ICF implosions.
Visual information without thermal energy may induce thermoregulatory-like cardiovascular responses
2013-01-01
Background Human core body temperature is kept quasi-constant regardless of varying thermal environments. It is well known that physiological thermoregulatory systems are under the control of central and peripheral sensory organs that are sensitive to thermal energy. If these systems wrongly respond to non-thermal stimuli, it may disturb human homeostasis. Methods Fifteen participants viewed video images evoking hot or cold impressions in a thermally constant environment. Cardiovascular indices were recorded during the experiments. Correlations between the ‘hot-cold’ impression scores and cardiovascular indices were calculated. Results The changes of heart rate, cardiac output, and total peripheral resistance were significantly correlated with the ‘hot-cold’ impression scores, and the tendencies were similar to those in actual thermal environments corresponding to the impressions. Conclusions The present results suggest that visual information without any thermal energy can affect physiological thermoregulatory systems at least superficially. To avoid such ‘virtual’ environments disturbing human homeostasis, further study and more attention are needed. PMID:24373765
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bachmann, B., E-mail: bachmann2@llnl.gov; Field, J.; Masters, N.
We have developed and fielded x-ray penumbral imaging on the National Ignition Facility in order to enable sub-10 μm resolution imaging of stagnated plasma cores (hot spots) of spherically shock compressed spheres and shell implosion targets. By utilizing circular tungsten and tantalum apertures with diameters ranging from 20 μm to 2 mm, in combination with image plate and gated x-ray detectors as well as imaging magnifications ranging from 4 to 64, we have demonstrated high-resolution imaging of hot spot plasmas at x-ray energies above 5 keV. Here we give an overview of the experimental design criteria involved and demonstrate themore » most relevant influences on the reconstruction of x-ray penumbral images, as well as mitigation strategies of image degrading effects like over-exposed pixels, artifacts, and photon limited source emission. We describe experimental results showing the advantages of x-ray penumbral imaging over conventional Fraunhofer and photon limited pinhole imaging and showcase how internal hot spot microstructures can be resolved.« less
Experimental and numerical study of physiological responses in hot environments.
Yang, Jie; Weng, Wenguo; Zhang, Baoting
2014-10-01
This paper proposed a multi-node human thermal model to predict human thermal responses in hot environments. The model was extended based on the Tanabe's work by considering the effects of high temperature on heat production, blood flow rate, and heat exchange coefficients. Five healthy men dressed in shorts were exposed in thermal neutral (29 °C) and high temperature (45 °C) environments. The rectal temperatures and skin temperatures of seven human body segments were continuously measured during the experiment. Validation of this model was conducted with experimental data. The results showed that the current model could accurately predict the skin and core temperatures in terms of the tendency and absolute values. In the human body segments expect calf and trunk, the temperature differences between the experimental data and the predicted results in high temperature environment were smaller than those in the thermally neutral environment conditions. The extended model was proved to be capable of predicting accurately human physiological responses in hot environments. Copyright © 2014 Elsevier Ltd. All rights reserved.
Encapsulated nano-heat-sinks for thermal management of heterogeneous chemical reactions.
Zhang, Minghui; Hong, Yan; Ding, Shujiang; Hu, Jianjun; Fan, Yunxiao; Voevodin, Andrey A; Su, Ming
2010-12-01
This paper describes a new way to control temperatures of heterogeneous exothermic reactions such as heterogeneous catalytic reaction and polymerization by using encapsulated nanoparticles of phase change materials as thermally functional additives. Silica-encapsulated indium nanoparticles and silica encapsulated paraffin nanoparticles are used to absorb heat released in catalytic reaction and to mitigate gel effect of polymerization, respectively. The local hot spots that are induced by non-homogenous catalyst packing, reactant concentration fluctuation, and abrupt change of polymerization rate lead to solid to liquid phase change of nanoparticle cores so as to avoid thermal runaway by converting energies from exothermic reactions to latent heat of fusion. By quenching local hot spots at initial stage, reaction rates do not rise significantly because the thermal energy produced in reaction is isothermally removed. Nanoparticles of phase change materials will open a new dimension for thermal management of exothermic reactions to quench local hot spots, prevent thermal runaway of reaction, and change product distribution.
INITIATION PROCESSES FOR THE 2013 MAY 13 X1.7 LIMB FLARE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shen, Jinhua; Wang, Ya; Zhou, Tuanhui
2017-01-20
For the X1.7 class flare on 2013 May 13 (SOL2013-05-13T01:53), its initiation process was well observed by the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamic Observatory and the Extreme UltraViolet Imager (EUVI) on board STEREO-B . The initiation process incorporates the following phenomena: an X-ray precursor that started ∼9 minutes before flare onset, two hot magnetic loops (as seen with AIA hot channels) forming a sigmoidal core magnetic structure (as seen with the EUVI), a rapidly formed magnetic flux rope (MFR) that expands outward, and a flare loop that contracts inward. The two hot magnetic loops were activatedmore » after the occurrence of the X-ray precursor. After activation, magnetic reconnection occurred between the two hot magnetic loops (inside the sigmoid structure), which produced the expanding MFR and the contracting flare loop (CFL). The MFR and CFL can only be seen with AIA hot and cool channels, respectively. For this flare, the real initiation time can be regarded as being from the starting time of the precursor, and its impulsive phase started when the MFR began its fast expansion. In addition, the CFL and the growing postflare magnetic loops are different loop systems, and the CFL was the product of magnetic reconnection between sheared magnetic fields that also produced the MFR.« less
Vincent, Grace E.; Aisbett, Brad; Larsen, Brianna; Ridgers, Nicola D.; Snow, Rod; Ferguson, Sally A.
2017-01-01
This study was designed to examine the effects of ambient heat on firefighters’ physical task performance, and physiological and perceptual responses when sleep restricted during simulated wildfire conditions. Thirty firefighters were randomly allocated to the sleep restricted (n = 17, SR; 19 °C, 4-h sleep opportunity) or hot and sleep restricted (n = 13, HOT + SR; 33 °C, 4-h sleep opportunity) condition. Firefighters performed two days of simulated, intermittent, self-paced work circuits comprising six firefighting tasks. Heart rate, and core temperature were measured continuously. After each task, firefighters reported their rating of perceived exertion and thermal sensation. Effort sensation was also reported after each work circuit. Fluids were consumed ad libitum. Urine volume and urine specific gravity were analysed. Sleep was monitored using polysomnography. There were no differences between the SR and HOT + SR groups in firefighters’ physiological responses, hydration status, ratings of perceived exertion, motivation, and four of the six firefighting tasks (charged hose advance, rake, hose rolling, static hose hold). Black out hose and lateral repositioning were adversely affected in the HOT + SR group. Working in hot conditions did not appear to consistently impair firefighters work performance, physiology, and perceptual responses. Future research should determine whether such findings remain true when individual tasks are performed over longer durations. PMID:28208688
Boiling water neutronic reactor incorporating a process inherent safety design
Forsberg, C.W.
1985-02-19
A boiling-water reactor core is positioned within a prestressed concrete reactor vessel of a size which will hold a supply of coolant water sufficient to submerge and cool the reactor core by boiling for a period of at least one week after shutdown. Separate volumes of hot, clean (nonborated) water for cooling during normal operation and cool highly borated water for emergency cooling and reactor shutdown are separated by an insulated wall during normal reactor operation with contact between the two water volumes being maintained at interfaces near the top and bottom ends of the reactor vessel. Means are provided for balancing the pressure of the two water volumes at the lower interface zone during normal operation to prevent entry of the cool borated water into the reactor core region, for detecting the onset of excessive power to coolant flow conditions in the reactor core and for detecting low water levels of reactor coolant. Cool borated water is permitted to flow into the reactor core when low reactor coolant levels or excessive power to coolant flow conditions are encountered.
Boiling water neutronic reactor incorporating a process inherent safety design
Forsberg, Charles W.
1987-01-01
A boiling-water reactor core is positioned within a prestressed concrete reactor vessel of a size which will hold a supply of coolant water sufficient to submerge and cool the reactor core by boiling for a period of at least one week after shutdown. Separate volumes of hot, clean (non-borated) water for cooling during normal operation and cool highly borated water for emergency cooling and reactor shutdown are separated by an insulated wall during normal reactor operation with contact between the two water volumes being maintained at interfaces near the top and bottom ends of the reactor vessel. Means are provided for balancing the pressure of the two volumes at the lower interface zone during normal operation to prevent entry of the cool borated water into the reactor core region, for detecting the onset of excessive power to coolant flow conditions in the reactor core and for detecting low water levels of reactor coolant. Cool borated water is permitted to flow into the reactor core when low reactor coolant levels or excessive power to coolant flow conditions are encountered.
Search for complex organic molecules in space
NASA Astrophysics Data System (ADS)
Ohishi, Masatoshi
2016-07-01
It was 1969 when the first organic molecule in space, H2CO, was discovered. Since then many organic molecules were discovered by using the NRAO 11 m (upgraded later to 12 m), Nobeyama 45 m, IRAM 30 m, and other highly sensitive radio telescopes as a result of close collaboration between radio astronomers and microwave spectroscopists. It is noteworthy that many famous organic molecules such as CH3OH, C2H5OH, (CH3)2O and CH3NH2 were detected by 1975. Organic molecules were found in so-called hot cores where molecules were thought to form on cold dust surfaces and then to evaporate by the UV photons emitted from the central star. These days organic molecules are known to exist not only in hot cores but in hot corinos (a warm, compact molecular clump found in the inner envelope of a class 0 protostar) and even protoplanetary disks. As was described above, major organic molecules were known since 1970s. It was very natural that astronomers considered a relationship between organic molecules in space and the origin of life. Several astronomers challenged to detect glycine and other prebiotic molecules without success. ALMA is expected to detect such important materials to further consider the gexogenous deliveryh hypothesis. In this paper I summarize the history in searching for complex organic molecules together with difficulties in observing very weak signals from larger species. The awfully long list of references at the end of this article may be the most useful part for readers who want to feel the exciting discovery stories.
Effects of solar radiation on endurance exercise capacity in a hot environment.
Otani, Hidenori; Kaya, Mitsuharu; Tamaki, Akira; Watson, Phillip; Maughan, Ronald J
2016-04-01
The present study investigated the effects of variations in solar radiation on endurance exercise capacity and thermoregulatory responses in a hot environment. Eight male volunteers performed four cycle exercise trials at 70 % maximum oxygen uptake until exhaustion in an environmental chamber maintained at 30 °C and 50 % relative humidity. Volunteers were tested under four solar radiation conditions: 800, 500, 250 and 0 W/m(2). Exercise time to exhaustion was less on the 800 W/m(2) trial (23 ± 4 min) than on all the other trials (500 W/m(2) 30 ± 7 min; P < 0.05, 250 W/m(2) 43 ± 10 min; P < 0.001, 0 W/m(2) 46 ± 10 min; P < 0.001), and on the 500 W/m(2) trial than the 250 W/m(2) (P < 0.05) and 0 W/m(2) (P < 0.01) trials. There were no differences in core (rectal) temperature, total sweat loss, heart rate, skin blood flow, cutaneous vascular conductance and percentage changes in plasma volume between trials (P > 0.05). Mean skin temperature was higher on the 800 W/m(2) trial than the 250 and 0 W/m(2) trials (P < 0.05), and on the 500 W/m(2) trial than the 0 W/m(2) trial (P < 0.05). The core-to-skin temperature gradient was narrower on the 800 W/m(2) trial than the 250 and 0 W/m(2) trials (P < 0.05). The present study demonstrates that endurance exercise capacity in a hot environment falls progressively as solar radiation increases.
NASA Astrophysics Data System (ADS)
Guo, Juan; Zhou, Xun; Wang, Lidong; Zhang, Yuqi; Shen, Xiaowei; Zhou, Haiyan; Ye, Shen; Fang, Bin
2018-06-01
Natural springs have the potential to provide important information on hydrogeochemical processes within aquifers. This study used traditional and classic technical methods and procedures to determine the characteristics and evolution of springs to gain further knowledge on the differences between hot saline springs and cold fresh springs. In a short river segment near Wenquanzhen in the eastern Sichuan Basin, southwest China, several natural springs coexist with total dissolved solids (TDS) ranging from less than 1 to 15 g/L and temperatures from 15 to 40 °C. The springs emanate from the outcropping Lower and Middle Triassic carbonates in the river valley cutting the core of an anticline. The cold springs are of Cl·HCO3-Na·Ca and Cl·SO4-Na types, and the hot saline springs are mainly of Cl-Na type. The chemistry of the springs has undergone some changes with time. The stable hydrogen and oxygen isotopes indicate that the spring waters are of a meteoric origin. The salinity of the springs originates from dissolution of minerals, including halite, gypsum, calcite and dolomite. The evolution of the springs involves the following mechanisms: the groundwater receives recharge from infiltration of precipitation, then undergoes deep circulation in the core of the anticline (incongruent dissolution of the salt-bearing strata occurs), and emerges in the river valley in the form of hot springs with high TDS. Groundwater also undergoes shallow circulation in the northern and southern flanks of the anticline and appears in the river valley in the form of cold springs with low TDS.
NASA Astrophysics Data System (ADS)
Guo, Juan; Zhou, Xun; Wang, Lidong; Zhang, Yuqi; Shen, Xiaowei; Zhou, Haiyan; Ye, Shen; Fang, Bin
2017-12-01
Natural springs have the potential to provide important information on hydrogeochemical processes within aquifers. This study used traditional and classic technical methods and procedures to determine the characteristics and evolution of springs to gain further knowledge on the differences between hot saline springs and cold fresh springs. In a short river segment near Wenquanzhen in the eastern Sichuan Basin, southwest China, several natural springs coexist with total dissolved solids (TDS) ranging from less than 1 to 15 g/L and temperatures from 15 to 40 °C. The springs emanate from the outcropping Lower and Middle Triassic carbonates in the river valley cutting the core of an anticline. The cold springs are of Cl·HCO3-Na·Ca and Cl·SO4-Na types, and the hot saline springs are mainly of Cl-Na type. The chemistry of the springs has undergone some changes with time. The stable hydrogen and oxygen isotopes indicate that the spring waters are of a meteoric origin. The salinity of the springs originates from dissolution of minerals, including halite, gypsum, calcite and dolomite. The evolution of the springs involves the following mechanisms: the groundwater receives recharge from infiltration of precipitation, then undergoes deep circulation in the core of the anticline (incongruent dissolution of the salt-bearing strata occurs), and emerges in the river valley in the form of hot springs with high TDS. Groundwater also undergoes shallow circulation in the northern and southern flanks of the anticline and appears in the river valley in the form of cold springs with low TDS.
Assessment of Effectiveness of Cool Coat in Reducing Heat Strain among Workers in Steel Industry.
Parameswarappa, S B; Narayana, J
2017-01-01
A research study was conducted to assess the effectiveness of cool coat in reducing heat strain among workers exposed to heat in a steel plant located in south India. The study consists of assessing heat strain of workers exposed to heat in a steel plant by measuring physiological reactions of workers such as pulse rate and core body temperature with and without cool coat. The coal coat taken for this study was procured from M/s Yamuna Industries, Noida. Out of 140 employees exposed to heat hazard, 101 employees were examined in this study. Study was done in important production units in steel plant having heat hazard. Workers were interviewed and examined and information regarding thermal comfort was collected. First, the heat strain was assessed when the workers were not using cool coats. The air temperature was measured at all hot zone workplaces and found in the range of 34 0 C to 39.4 0 C (Mean: 36.54 0 C & S.D: 1.54). Physiological response such as core body temperature, pulse rate and blood pressure of workers exposed to heat hazard were measured before & after work to know the heat strain sustained by workers when they were working. Maximum core body temperature after work was found to be 39.3 0 C (Mean; 38.52 & S.D; 0.7). Maximum pulse rate of workers after work was found to be 120 beats/minute (Mean; 94.96 beats/minute, S.D: 13.11). The study indicate core body temperature of workers was found more than the permissible exposure limit prescribed by ACGIH, indicating the heat strain sustained by workers is significant, whereas the pulse rate and blood pressure was found normal & not exceeded the limits. Second, with cool coat, the heat strain was assessed among 10 workers selected from the 101 employees. Core body temperature was measured before and soon after work, The core body temperature recorded soon after work was in the range of 35.5 - 37.20C (Mean 36.36, SD= 0.52), indicating a drop in the core body temperature. In this study, a core body temperature rise in the range of 1 0 -1.4 0 C was noticed when the employees were not wearing cool coats. Whereas, with the usage of cool coat a rise in core body temperature was not found and in many coat wearing workers a drop in core body temperature (0.2 to 0.9 0 C) was noticed. Employees revealed that the cool coats was comfortable to use and provided the thermal comforts. The study concluded that the cool coat taken for this study was found effective in reducing the heat strain.
Assessment of Effectiveness of Cool Coat in Reducing Heat Strain among Workers in Steel Industry
Parameswarappa, S. B.; Narayana, J.
2017-01-01
A research study was conducted to assess the effectiveness of cool coat in reducing heat strain among workers exposed to heat in a steel plant located in south India. The study consists of assessing heat strain of workers exposed to heat in a steel plant by measuring physiological reactions of workers such as pulse rate and core body temperature with and without cool coat. The coal coat taken for this study was procured from M/s Yamuna Industries, Noida. Out of 140 employees exposed to heat hazard, 101 employees were examined in this study. Study was done in important production units in steel plant having heat hazard. Workers were interviewed and examined and information regarding thermal comfort was collected. First, the heat strain was assessed when the workers were not using cool coats. The air temperature was measured at all hot zone workplaces and found in the range of 34 0 C to 39.4 0 C (Mean: 36.54 0 C & S.D: 1.54). Physiological response such as core body temperature, pulse rate and blood pressure of workers exposed to heat hazard were measured before & after work to know the heat strain sustained by workers when they were working. Maximum core body temperature after work was found to be 39.3 0 C (Mean; 38.52 & S.D; 0.7). Maximum pulse rate of workers after work was found to be 120 beats/minute (Mean; 94.96 beats/minute, S.D: 13.11). The study indicate core body temperature of workers was found more than the permissible exposure limit prescribed by ACGIH, indicating the heat strain sustained by workers is significant, whereas the pulse rate and blood pressure was found normal & not exceeded the limits. Second, with cool coat, the heat strain was assessed among 10 workers selected from the 101 employees. Core body temperature was measured before and soon after work, The core body temperature recorded soon after work was in the range of 35.5 - 37.20C (Mean 36.36, SD= 0.52), indicating a drop in the core body temperature. In this study, a core body temperature rise in the range of 1 0 -1.4 0 C was noticed when the employees were not wearing cool coats. Whereas, with the usage of cool coat a rise in core body temperature was not found and in many coat wearing workers a drop in core body temperature (0.2 to 0.9 0 C) was noticed. Employees revealed that the cool coats was comfortable to use and provided the thermal comforts. The study concluded that the cool coat taken for this study was found effective in reducing the heat strain. PMID:29391745
Coupled Neutronics Thermal-Hydraulic Solution of a Full-Core PWR Using VERA-CS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Clarno, Kevin T; Palmtag, Scott; Davidson, Gregory G
2014-01-01
The Consortium for Advanced Simulation of Light Water Reactors (CASL) is developing a core simulator called VERA-CS to model operating PWR reactors with high resolution. This paper describes how the development of VERA-CS is being driven by a set of progression benchmark problems that specify the delivery of useful capability in discrete steps. As part of this development, this paper will describe the current capability of VERA-CS to perform a multiphysics simulation of an operating PWR at Hot Full Power (HFP) conditions using a set of existing computer codes coupled together in a novel method. Results for several single-assembly casesmore » are shown that demonstrate coupling for different boron concentrations and power levels. Finally, high-resolution results are shown for a full-core PWR reactor modeled in quarter-symmetry.« less
Removal of heavy metal ions from aqueous solutions using lignocellulosic fibers
Beom-Goo Lee; Roger M. Rowell
2004-01-01
Spruce, coconut coir, sugarcane bagasse, kenaf bast, kenaf core, and cotton were tested for their ability to remove copper, nickel and zinc ions from aqueous-solutions as a function of their lignin content. The fibers were analyzed for sugar and lignin content and extracted with diethyl ether, ethyl alcohol. hot water, or 1% sodium hydroxide. The order of lignin...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bitter, M.; von Goeler, S.; Horton, R.
1979-01-29
Ion-temperature results are deduced from Doppler-broadening measurements of the K..cap alpha.. (1s-2p) resonance line emitted from heliumlike iron impurity ions in the hot central core of PLT (Princeton Large Torus) tokamak discharges. The measurements were performed using a high-resolution Bragg-crystal spectrometer with a multiwire proportional counter.
Pressing of three-layer, dry-formed MDF with binderless hardboard faces
Otto Suchsland; George E. Woodson; Charles W. McMillin
1986-01-01
Severely cooked Masonite pulp was used as face material in three-layer experimental medium-density fiberboard (MDF). The core layer consisted of conventional MDF furnish with resin binder added. The faces were formed absolutely dry without additives of any kind. The three-layer mat was hot-pressed to overall densities ranging from 44 to 56 pcf. The faces had hardboard-...
Beyond the Core: The Hot Topic(al) Alternative to the Survey-Based Introduction to Sociology Course
ERIC Educational Resources Information Center
Schwartz, Michael; Smith, R. Tyson
2010-01-01
In the following paper we argue that the conventional "Introduction to Sociology" survey course should be restructured because such courses try to survey an unsurveyable body of knowledge and they do not teach the application of sociological research. The conventional intro course should be replaced with an intro course that surveys the types of…
Radial distribution of metals in the hot intra-cluster medium as observed by XMM-Newton
NASA Astrophysics Data System (ADS)
Mernier, F.; de Plaa, J.; Kaastra, J.; Zhang, Y.; Akamatsu, H.; Gu, L.; Mao, J.; Pinto, C.; Reiprich, T.; Sanders, J.
2017-10-01
The hot intra-cluster medium (ICM), which accounts for ˜80% of the baryonic content in galaxy clusters, is rich in heavy elements. Since these metals have been produced by stars and supernovae before enriching the ICM, measuring metal abundance distributions in galaxy clusters and groups provides essential clues to determine the main astrophysical source(s) and epoch(s) of the ICM enrichment. In this work, we present radial abundance profiles averaged over 44 nearby cool-core galaxy clusters, groups, and massive ellipticals (the CHEERS sample) measured with XMM-Newton EPIC. While most of the Fe of the Universe is thought to be synthesised by Type Ia supernovae (SNIa), lighter elements, such as O, Mg, Si or S, are mostly produced by core-collapse supernovae (SNcc). The derived average radial profiles of the O, Mg, Si, S, Ar, Ca, Fe, and Ni abundances out to ˜ 0.5 r_{500} allows us to accurately compare the distributions of SNIa and SNcc products in clusters and groups. By comparing our results with recent chemo-dynamical simulations, we discuss the interpretation of the profiles in the context of early and late ICM enrichments.
Surface states in the photoionization of high-quality CdSe core/shell nanocrystals.
Li, Shu; Steigerwald, Michael L; Brus, Louis E
2009-05-26
We use electric force microscopy (EFM) to study single nanocrystal photoionization in two classes of high-quality nanocrystals whose exciton luminescence quantum yields approach unity in solution. The CdSe/CdS/ZnS core/shell nanocrystals do not photoionize, while the CdSe/CdS nanocrystals do show substantial photoionization. This verifies the theoretical prediction that the ZnS shell confines the excited electron within the nanocrystal. Despite the high luminescence quantum yield, photoionization varies substantially among the CdSe/CdS nanocrystals. We have studied the nanocrystal photoionization with both UV (396 nm) and green (532 nm) light, and we have found that the magnitude of the charge due to photoionization per absorbed photon is greater for UV excitation than for green excitation. A fraction of the photoionization occurs directly via a "hot electron" process, using trap states that are either on the particle surface, within the ligand sphere, or within the silicon oxide layer. This must occur without relaxation to the thermalized, lowest-energy, emitting exciton. We discuss the occurrence of hot carrier processes that are common to photoionization, luminescence blinking, and the fast transient optical absorption that is associated with multiple exciton generation MEG studies.
Subgrid Modeling of AGN-driven Turbulence in Galaxy Clusters
NASA Astrophysics Data System (ADS)
Scannapieco, Evan; Brüggen, Marcus
2008-10-01
Hot, underdense bubbles powered by active galactic nuclei (AGNs) are likely to play a key role in halting catastrophic cooling in the centers of cool-core galaxy clusters. We present three-dimensional simulations that capture the evolution of such bubbles, using an adaptive mesh hydrodynamic code, FLASH3, to which we have added a subgrid model of turbulence and mixing. While pure hydro simulations indicate that AGN bubbles are disrupted into resolution-dependent pockets of underdense gas, proper modeling of subgrid turbulence indicates that this is a poor approximation to a turbulent cascade that continues far beyond the resolution limit. Instead, Rayleigh-Taylor instabilities act to effectively mix the heated region with its surroundings, while at the same time preserving it as a coherent structure, consistent with observations. Thus, bubbles are transformed into hot clouds of mixed material as they move outward in the hydrostatic intracluster medium (ICM), much as large airbursts lead to a distinctive "mushroom cloud" structure as they rise in the hydrostatic atmosphere of Earth. Properly capturing the evolution of such clouds has important implications for many ICM properties. In particular, it significantly changes the impact of AGNs on the distribution of entropy and metals in cool-core clusters such as Perseus.
A Search for Interstellar Oxiranecarbonitrile (C3H3NO)
NASA Technical Reports Server (NTRS)
Dicken, J. E.; Irvine, W. M.; Ohishi, M.; Arrhenius, G.; Bauder, A.; Mueller, F.; Eschenmoser, A.
1996-01-01
We report a search in cold, quiescent and in 'hot core' type interstellar molecular clouds for the small cyclic molecule oxiranecarbonitrile (C3H3NO), which has been suggested as a precursor of important prebiotic molecules. We have determined upper limits to the column density and fractional abundance for the observed sources and find that, typically, the fractional abundance by number relative to molecular hydrogen Of C3H3NO is less than a few times 10(exp -10). This limit is one to two orders of magnitude less than the measured abundance of such similarly complex species as CH3CH2CN and HCOOCH3 in well-studied hot cores. A number of astrochemical discoveries were made, including the first detection of the species CH3CH2CN in the massive star-forming clouds G34.3+0.2 and W51M and the first astronomical detections of some eight rotational transitions of CH3CH2CN, CH3CCH, and HCOOCH3. In addition, we found 8 emission lines in the 89 GHz region and 18 in the 102 GHz region which we were unable to assign.
Chemical modelling of glycolaldehyde and ethylene glycol in star-forming regions
NASA Astrophysics Data System (ADS)
Coutens, A.; Viti, S.; Rawlings, J. M. C.; Beltrán, M. T.; Holdship, J.; Jiménez-Serra, I.; Quénard, D.; Rivilla, V. M.
2018-04-01
Glycolaldehyde (HOCH2CHO) and ethylene glycol ((CH2OH)2) are two complex organic molecules detected in the hot cores and hot corinos of several star-forming regions. The ethylene glycol/glycolaldehyde abundance ratio seems to show an increase with the source luminosity. In the literature, several surface-chemistry formation mechanisms have been proposed for these two species. With the UCLCHEM chemical code, we explored the different scenarios and compared the predictions for a range of sources of different luminosities with the observations. None of the scenarios reproduce perfectly the trend. A better agreement is, however, found for a formation through recombination of two HCO radicals followed by successive hydrogenations. The reaction between HCO and CH2OH could also contribute to the formation of glycolaldehyde in addition to the hydrogenation pathway. The predictions are improved when a trend of decreasing H2 density within the core region with T≥100 K as a function of luminosity is included in the model. Destruction reactions of complex organic molecules in the gas phase would also need to be investigated, since they can affect the abundance ratios once the species have desorbed in the warm inner regions of the star-forming regions.
Thermophysiological responses caused by ballistic bullet-proof vests.
Lehmacher, E J; Jansing, P; Küpper, T
2007-01-01
Little data is available concerning the heat stress experienced by members of staff who wear bullet-proof vests in a warm or hot environment. For this reason, knowledge is limited and, consequently, preventative advice on how to avoid heat sickness or hyperthermia is required. Skin and body temperatures, fluid loss and the heart rate of 30 persons (15 test persons versus 15 control persons) were measured in three situations typical of the test participants' job situations. Environmental data (wind velocity, air humidity, air temperature) were measured during the tests as well. Whereas there was a significant increase in skin temperatures, there was no difference in the core body temperatures of both groups. Maximum core body temperature remained well below 38 degrees C in all subjects. Test persons wearing vests showed a fluid loss of 1.1 l on average (non-vest wearers in the control group 1.0 l). There is no increased risk of heat stroke or hyperthermia for employees wearing bullet-proof vests in comparison with employees who do not wear them. Both groups, however, should be advised to ensure an adequate intake of fluid to maintain a healthy body fluid balance when working in hot environments.
Saturation scanning of ubiquitin variants reveals a common hot spot for binding to USP2 and USP21.
Leung, Isabel; Dekel, Ayelet; Shifman, Julia M; Sidhu, Sachdev S
2016-08-02
A detailed understanding of the molecular mechanisms whereby ubiquitin (Ub) recognizes enzymes in the Ub proteasome system is crucial for understanding the biological function of Ub. Many structures of Ub complexes have been solved and, in most cases, reveal a large structural epitope on a common face of the Ub molecule. However, owing to the generally weak nature of these interactions, it has been difficult to map in detail the functional contributions of individual Ub side chains to affinity and specificity. Here we took advantage of Ub variants (Ubvs) that bind tightly to particular Ub-specific proteases (USPs) and used phage display and saturation scanning mutagenesis to comprehensively map functional epitopes within the structural epitopes. We found that Ubvs that bind to USP2 or USP21 contain a remarkably similar core functional epitope, or "hot spot," consisting mainly of positions that are conserved as the wild type sequence, but also some positions that prefer mutant sequences. The Ubv core functional epitope contacts residues that are conserved in the human USP family, and thus it is likely important for the interactions of Ub across many family members.
Molecular interfaces for plasmonic hot electron photovoltaics
NASA Astrophysics Data System (ADS)
Pelayo García de Arquer, F.; Mihi, Agustín; Konstantatos, Gerasimos
2015-01-01
The use of self-assembled monolayers (SAMs) to improve and tailor the photovoltaic performance of plasmonic hot-electron Schottky solar cells is presented. SAMs allow the simultaneous control of open-circuit voltage, hot-electron injection and short-circuit current. To that end, a plurality of molecule structural parameters can be adjusted: SAM molecule's length can be adjusted to control plasmonic hot electron injection. Modifying SAMs dipole moment allows for a precise tuning of the open-circuit voltage. The functionalization of the SAM can also be selected to modify short-circuit current. This allows the simultaneous achievement of high open-circuit voltages (0.56 V) and fill-factors (0.58), IPCE above 5% at the plasmon resonance and maximum power-conversion efficiencies of 0.11%, record for this class of devices.The use of self-assembled monolayers (SAMs) to improve and tailor the photovoltaic performance of plasmonic hot-electron Schottky solar cells is presented. SAMs allow the simultaneous control of open-circuit voltage, hot-electron injection and short-circuit current. To that end, a plurality of molecule structural parameters can be adjusted: SAM molecule's length can be adjusted to control plasmonic hot electron injection. Modifying SAMs dipole moment allows for a precise tuning of the open-circuit voltage. The functionalization of the SAM can also be selected to modify short-circuit current. This allows the simultaneous achievement of high open-circuit voltages (0.56 V) and fill-factors (0.58), IPCE above 5% at the plasmon resonance and maximum power-conversion efficiencies of 0.11%, record for this class of devices. Electronic supplementary information (ESI) available: Contact-potential differentiometry measurements, FTIR characterization, performance statistics and gold devices. See DOI: 10.1039/c4nr06356b
New steps in testing the Tidal Downsizing hypothesis for planet formation
NASA Astrophysics Data System (ADS)
Nayakshin, S.
2013-09-01
Broadly speaking, there are two opposite views on how planet formation proceeds. The first of these is the Core Accretion (CA), a well established theory in which assembly of all planets occurs in the bottom-up direction. The second one is a modified gravitational disc in- stability model, which originally was thought to form only giant gaseous planets at large distances from the tar (e.g., Rafikov 2005). Now it emerges that migrating gaseous clumps may form not only giant planets but also terrestrial-like planets if dust sediments into the cores and the clumps' gas is removed by tidal disruption (Boley et al 2010, Nayakshin 2010; also reviewed in the upcoming PPVI by Helled et al 2013). This top-down scenario is referred to as "Tidal Downsizing" (TD) hypothesis. While TD hypothesis may potentially explain all of planet populations at any separation from the parent star (as planets migrate from 100 AU all the way to their disruption at ˜0.1 AU; Nayakshin and Lodato 2012), this scenario is currently in the embryonic state and needs further detailed calculations. Here we present several new calculations aimed at testing the theory with observations of exoplanets and young accreting stars possibly in the process of planet formation. (1) Nayakshin (2011) proposed that young massive "hot jupiters" may actually be tidally disrupted by the gravity of their parent stars if they migrate inward too quickly. If a significant fraction of dust grains managed to sediment into the centres of these gas clumps before they are disrupted, the solid cores are left behind as hot super-Earths and "hot neptunes". The discplanet interaction before and during planet disruption was modelled in detail by Nayakshin and Lodato (2012), who showed that the process of tidal disruption produces FU-Ori like accretion events onto the parent star. This model thus may account for both the hot planets observed and episodic accretion of young stars (Dunham and Vorobyov 2012). Another crucial prediction of our model is that giant young proto-planets, in addition to interrupting accretion flows by creating deep gaps, can also feed their protostars by "restarting" the accretion flows. Since dust sediments and is locked in the solid cores, the envelopes of these proto-planets are dust-poor. Therefore, in Nayakshin (2013) we proposed that the observed transition discs with large inner holes, accreting gas but not dust, may in fact be exactly the systems accreting dust-poor envelopes of giant planets being in the process of "downsizing". We shall also discuss whether this model can acount for some of the most challenging exoplanetary systems found by Kepler, such as the densly packed multiplanet worlds Kepler 36 and Kepler 11. The obvious challenge is that bringing in a massive giant planet could destabilise the orbits of the inner lower mass planets. (2) Whether the massive young protoplanets born by gravitational instability at 100 AU migrate rapidly inward (which is the key assumption of TD) or stay behind and accrete gas rapidly to become Brown Dwarfs is a key issue for both planet and low mass binary companion formation fields. Population synthesis models based on analytical estimates of the process (Forgan and Rice, 2013) show that only a few percent of their theoretical discs are in the TD regime; most produce BDs and low mass stars, as previously found by Stamattelos and Whitworth (2009). Nayakshin and Cha (2013; MNRAS accepted) study the effect of radiative preheating from growing giant planets on their immediate disc environment. It is found that gas in vicinity of the protostar is significantly hotter than found in simulations and analytical estimates that neglect the preheating effect. Clumps less massive than 6 Jupiter masses are found to build massive hot radiative atmospheres around them, "protecting" them from further gas accretion. These clumps rapidly migrate in and are in the TD regime, in whereas clumps more massive than 10 Jupiter masses indeed form BDs or more massive stars. We believe he preheating effect discussed here must be incorporated in simulations of gravitationally unstable discs to reliably predict the outcome. Most current simulations of such discs over-predict the population of BDs and low mass stellar companions. (3) We shall also present our ongoing work to calculate chemical composition of the solid cores formed in the TD hypothesis. We show that it is vertually impossible to form water-dominated massive solid cores since the compressional heat and rapid radiative cooling of the clumps preclude sedimentation of water ice (except for a very low density, small mass gas clumps). As the result TD predicts that composition of "hot" sub-jovian exoplanets should be dominated by rock/Fe and H/He mixes.
A new class of g-modes in neutron stars
NASA Technical Reports Server (NTRS)
Reisenegger, Andreas; Goldreich, Peter
1992-01-01
Because a neutron star is born hot, its internal composition is close to chemical equilibrium. In the fluid core, this implies that the ratio of the number densities of charged particles (protons and electrons) to neutrons is an increasing function of the mass density. This composition gradient stably stratifies the matter giving rise to a Brunt-Vaisala frequency N of about 500/s. Consequently, a neutron star core provides a cavity that supports gravity modes (g-modes). These g-modes are distinct from those previously identified with the thermal stratification of the surface layers and the chemical stratification of the crust. We compute the lowest-order, quadrupolar, g-modes for cold, Newtonian, neutron star models with M/solar M = 0.581 and M/solar M = 1.405, and show that the crustal and core g-modes have similar periods. We also discuss damping mechanisms and estimate damping rates for the core g-modes. Particular attention is paid to damping due to the emission of gravitational radiation.
Fiorini, D; Boarelli, M C
2016-07-01
When hydrogen is used as carrier gas, carbon-carbon double bonds may be hydrogenated in the hot gas chromatograph (GC) injector if introduced by solid-phase microextraction (SPME). SPME fibers coated with polydimethylsiloxane (PDMS)/carboxen/divinylbenzene (DVB), PDMS/carboxen, polyacrylate, PDMS/DVB and PDMS on fused silica, stableflex or metal alloy core have been tested with fatty acid methyl esters (FAMEs) from olive oil. Using coatings containing DVB, hydrogenation took place with high conversion rates (82.0-92.9%) independently of the core material. With all fibers having a metal core, hydrogenation was observed to a certain extent (27.4-85.3%). PDMS, PDMS/carboxen and polyacrylate coated fibers with a fused silica or stableflex core resulted in negligible hydrogenation (0.2-2.5%). The occurrence of hydrogenation was confirmed also with other substances containing carbon-carbon double bonds (n-alkenes, alkenoic acids, mono- and polyunsaturated fatty acid methyl and ethyl esters). Copyright © 2016 Elsevier B.V. All rights reserved.
Conductivity tensor for anisotropic plasma in gyrokinetic theory
Porazik, Peter; Johnson, Jay R.
2017-05-18
Comprehensive non-invasive spectroscopic techniques and electrical measurements of the carbon arc revealed two distinguishable plasma synthesis regions in the radial direction normal to the arc axis. These regions, which are defined as the arc core and the arc periphery, are shown to have very different compositions of carbon species with different densities and temperatures. The colder arc periphery is dominated by carbon diatomic molecules (C-2), which are in the minority in the composition of the hot arc core. These differences are due to a highly non-uniform distribution of the arc current, which is mainly conducted through the arc core populatedmore » with carbon atoms and ions. Therefore, the ablation of the graphite anode is governed by the arc core, while the formation of carbon molecules occurs in the colder arc periphery. This result is consistent with previous predictions that the plasma environment in the arc periphery is suitable for synthesis of carbon nanotubes.« less
Conductivity tensor for anisotropic plasma in gyrokinetic theory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Porazik, Peter; Johnson, Jay R.
Comprehensive non-invasive spectroscopic techniques and electrical measurements of the carbon arc revealed two distinguishable plasma synthesis regions in the radial direction normal to the arc axis. These regions, which are defined as the arc core and the arc periphery, are shown to have very different compositions of carbon species with different densities and temperatures. The colder arc periphery is dominated by carbon diatomic molecules (C-2), which are in the minority in the composition of the hot arc core. These differences are due to a highly non-uniform distribution of the arc current, which is mainly conducted through the arc core populatedmore » with carbon atoms and ions. Therefore, the ablation of the graphite anode is governed by the arc core, while the formation of carbon molecules occurs in the colder arc periphery. This result is consistent with previous predictions that the plasma environment in the arc periphery is suitable for synthesis of carbon nanotubes.« less
NEUTRONIC REACTOR OPERATIONAL METHOD AND CORE SYSTEM
Winters, C.E.; Graham, C.B.; Culver, J.S.; Wilson, R.H.
1960-07-19
Homogeneous neutronic reactor systems are described wherein an aqueous fuel solution is continuously circulated through a spherical core tank. The pumped fuel solution-is injected tangentially into the hollow spherical interior, thereby maintaining vigorous rotation of the solution within the tank in the form of a vortex; gaseous radiolytic decomposition products concentrate within the axial vortex cavity. The evolved gas is continuously discharged through a gas- outlet port registering with an extremity of the vortex cavity. and the solution stream is discharged through an annular liquid outlet port concentrically encircling the gas outlet by virtue of which the vortex and its cavity are maintained precisely axially aligned with the gas outlet. A primary heat exchanger extracts useful heat from the hot effluent fuel solution before its recirculation into the core tank. Hollow cylinders and other alternative core- tank configurations defining geometric volumes of revolution about a principal axis are also covered. AEC's Homogeneous Reactor Experiment No. 1 is a preferred embodiment.
Overdensities of SMGs around WISE-selected, ultraluminous, high-redshift AGNs
NASA Astrophysics Data System (ADS)
Jones, Suzy F.; Blain, Andrew W.; Assef, Roberto J.; Eisenhardt, Peter; Lonsdale, Carol; Condon, James; Farrah, Duncan; Tsai, Chao-Wei; Bridge, Carrie; Wu, Jingwen; Wright, Edward L.; Jarrett, Tom
2017-08-01
We investigate extremely luminous dusty galaxies in the environments around Wide-field Infrared Survey Explorer (WISE)-selected hot dust-obscured galaxies (Hot DOGs) and WISE/radio-selected active galactic nuclei (AGNs) at average redshifts of z = 2.7 and 1.7, respectively. Previous observations have detected overdensities of companion submillimetre-selected sources around 10 Hot DOGs and 30 WISE/radio AGNs, with overdensities of ˜2-3 and ˜5-6, respectively. We find that the space densities in both samples to be overdense compared to normal star-forming galaxies and submillimetre galaxies (SMGs) in the Submillimetre Common-User Bolometer Array 2 (SCUBA-2) Cosmology Legacy Survey (S2CLS). Both samples of companion sources have consistent mid-infrared (mid-IR) colours and mid-IR to submm ratios as SMGs. The brighter population around WISE/radio AGNs could be responsible for the higher overdensity reported. We also find that the star formation rate densities are higher than the field, but consistent with clusters of dusty galaxies. WISE-selected AGNs appear to be good signposts for protoclusters at high redshift on arcmin scales. The results reported here provide an upper limit to the strength of angular clustering using the two-point correlation function. Monte Carlo simulations show no angular correlation, which could indicate protoclusters on scales larger than the SCUBA-2 1.5-arcmin scale maps.
Lundgren, Karin; Kuklane, Kalev; Venugopal, Vidhya
2014-01-01
Background Heat stress is a major occupational problem in India that can cause adverse health effects and reduce work productivity. This paper explores this problem and its impacts in selected workplaces, including industrial, service, and agricultural sectors in Chennai, India. Design Quantitative measurements of heat stress, workload estimations, and clothing testing, and qualitative information on health impacts, productivity loss, etc., were collected. Heat strain and associated impacts on labour productivity between the seasons were assessed using the International Standard ISO 7933:2004, which applies the Predicted Heat Strain (PHS) model. Results and conclusions All workplaces surveyed had very high heat exposure in the hot season (Wet Bulb Globe Temperature x¯ =29.7), often reaching the international standard safe work values (ISO 7243:1989). Most workers had moderate to high workloads (170–220 W/m2), with some exposed to direct sun. Clothing was found to be problematic, with high insulation values in relation to the heat exposure. Females were found to be more vulnerable because of the extra insulation added from wearing a protective shirt on top of traditional clothing (0.96 clo) while working. When analysing heat strain – in terms of core temperature and dehydration – and associated productivity loss in the PHS model, the parameters showed significant impacts that affected productivity in all workplaces, apart from the laundry facility, especially during the hot season. For example, in the canteen, the core temperature limit of 38°C predicted by the model was reached in only 64 min for women. With the expected increases in temperature due to climate change, additional preventive actions have to be implemented to prevent further productivity losses and adverse health impacts. Overall, this study presented insight into using a thermo-physiological model to estimate productivity loss due to heat exposure in workplaces. This is the first time the PHS model has been used for this purpose. An exploratory approach was taken for further development of the model. PMID:25373413
Our Galactic Neighbor Hosts Complex Organic Molecules
NASA Astrophysics Data System (ADS)
Hensley, Kerry
2018-03-01
For the first time, data from the Atacama Large Millimeter/submillimeter Array (ALMA) reveal the presence of methyl formate and dimethyl ether in a star-forming region outside our galaxy. This discovery has important implications for the formation and survival of complex organic compounds importantfor the formation of life in low-metallicity galaxies bothyoung and old.No Simple Picture of Complex Molecule FormationALMA, pictured here with the Magellanic Clouds above, has observed organic molecules in our Milky Way Galaxy and beyond. [ESO/C. Malin]Complex organic molecules (those with at least six atoms, one or more of which must be carbon) are the precursors to the building blocks of life. Knowing how and where complex organic molecules can form is a key part of understanding how life came to be on Earth and how it might arise elsewhere in the universe. From exoplanet atmospheres to interstellar space, complex organic molecules are ubiquitous in the Milky Way.In our galaxy, complex organic molecules are often found in the intense environments of hot cores clumps of dense molecular gas surrounding the sites of star formation. However, its not yet fully understood how the complex organic molecules found in hot cores come to be. One possibility is that the compounds condense onto cold dust grains long before the young stars begin heating their natal shrouds. Alternatively, they might assemble themselves from the hot, dense gas surrounding the blazing protostars.Composite infrared and optical image of the N 113 star-forming region in the LMC. The ALMA coverage is indicated by the gray line. Click to enlarge. [Sewio et al. 2018]Detecting Complexity, a Galaxy AwayUsing ALMA, a team of researchers led by Marta Sewio (NASA Goddard Space Flight Center) recently detected two complex organic molecules methyl formate and dimethyl ether for the first time in our neighboring galaxy, the Large Magellanic Cloud (LMC). Previous searches for organic molecules in the LMC detected small amounts of methanol, the parentmolecule of the two newly-discovered compounds. By revealing the spectral signatures of dimethyl ether and methyl formate, Sewio and collaboratorsfurther prove thatorganic chemistry is hard at work in hot cores in the LMC.This discovery is momentous because dwarf galaxies like theLMC tend to have a lower abundance of the heavy elements that make up complex organic molecules most importantly, oxygen, carbon, and nitrogen. Beyond lacking the raw materials necessary to create complex molecules, the gas of low-metallicity galaxies does a poorer job preventing the penetration of high-energy photons. The impinging photons warm dust grains, resulting in a lower probability of forming and maintaining complex organic molecules. Despite this, organic molecules appear to beable todevelop and persist which has exciting implications for organic chemistry in low-metallicity environments.ALMA observation of emission by methyl formate in a hot core in the LMC.[Adapted from Sewio et al. 2018]A Lens into the PastIn the early universe, before the budding galaxies have had time to upcycle their abundant hydrogen into heavier elements, organic chemistry is thought to proceed slowly or not at all. The discovery of complex organic molecules in a nearby low-metallicity galaxy upends this theory and propels us toward a better understanding of the organic chemistry in the early universe.CitationMarta Sewio et al 2018ApJL853L19. doi:10.3847/2041-8213/aaa079
Are menopausal hot flashes an evolutionary byproduct of postpartum warming?
Sievert, Lynnette Leidy; Masley, Allison
2015-04-01
Hot flashes are commonly associated with menopause, and some researchers have questioned whether the widespread phenomenon may somehow be adaptive. It has been hypothesized that hot flashes were selected to occur during the hypoestrogenic postpartum period as a mechanism to warm infants. The purpose of this study was to test whether postpartum hot flashes are similar to hot flashes associated with menopause and whether postpartum hot flashes are concordant with breast-feeding episodes. Women who gave birth within the past year (n = 20) and a comparison group of women who had not given birth in the past 2 years (n = 14) participated in interviews and anthropometric measures. All wore ambulatory skin conductance monitors for a mean of 6.5 hours during afternoons and early evenings. New mothers also recorded breast-feeding episodes. Objectively measured and subjectively reported hot flashes were compared between groups and in relation to breast-feeding and other variables. Age of infants ranged from 4 days to 11 months. New mothers were more likely to report feeling warmer than the comparison group (100% vs 7%) but were not significantly more likely to demonstrate hot flashes (35% vs 50%) or to report hot flashes (30% vs 21%) during the study period. Of 75 breast-feeding episodes, only 4% were concurrent with an objective hot flash, and only 9% were concurrent with a subjective hot flash. This study does not support the hypothesis that menopausal-like hot flashes evolved to warm infants during the postpartum period.
Hot spots, indicator taxa, complementarity and optimal networks of taiga.
Virolainen, K M; Ahlroth, P; Hyvärinen, E; Korkeamäki, E; Mattila, J; Päiivinen, J; Rintala, T; Suomi, T; Suhonen, J
2000-01-01
If hot spots for different taxa coincide, priority-setting surveys in a region could be carried out more cheaply by focusing on indicator taxa. Several previous studies show that hot spots of different taxa rarely coincide. However, in tropical areas indicator taxa may be used in selecting complementary networks to represent biodiversity as a whole. We studied beetles (Coleoptera), Heteroptera, polypores or bracket fungi (Polyporaceae) and vascular plants of old growth boreal taiga forests. Optimal networks for Heteroptera maximized the high overall species richness of beetles and vascular plants, but these networks were least favourable options for polypores. Polypores are an important group indicating the conservation value of old growth taiga forests. Random selection provided a better option. Thus, certain groups may function as good indicators for maximizing the overall species richness of some taxonomic groups, but all taxa should be examined separately. PMID:10885520
NASA Astrophysics Data System (ADS)
Gao, Rui; Ge, Wen-jun; Miao, Shu; Zhang, Tao; Wang, Xian-ping; Fang, Qian-feng
2016-03-01
The grain morphology, nano-oxide particles and mechanical properties of oxide dispersion strengthened (ODS)-316L austenitic steel synthesized by electron beam selective melting (EBSM) technique with different post-working processes, were explored in this study. The ODS-316L austenitic steel with superfine nano-sized oxide particles of 30-40 nm exhibits good tensile strength (412 MPa) and large total elongation (about 51%) due to the pinning effect of uniform distributed oxide particles on dislocations. After hot rolling, the specimen exhibits a higher tensile strength of 482 MPa, but the elongation decreases to 31.8% owing to the introduction of high-density dislocations. The subsequent heat treatment eliminates the grain defects induced by hot rolling and increases the randomly orientated grains, which further improves the strength and ductility of EBSM ODS-316L steel.
NASA Astrophysics Data System (ADS)
Jehl, Zacharie; Suchet, Daniel; Julian, Anatole; Bernard, Cyril; Miyashita, Naoya; Gibelli, Francois; Okada, Yoshitaka; Guillemolles, Jean-Francois
2017-02-01
Double resonant tunneling barriers are considered for an application as energy selective contacts in hot carrier solar cells. Experimental symmetric and asymmetric double resonant tunneling barriers are realized by molecular beam epitaxy and characterized by temperature dependent current-voltage measurements. The negative differential resistance signal is enhanced for asymmetric heterostructures, and remains unchanged between low- and room-temperatures. Within Tsu-Esaki description of the tunnel current, this observation can be explained by the voltage dependence of the tunnel transmission amplitude, which presents a resonance under finite bias for asymmetric structures. This effect is notably discussed with respect to series resistance. Different parameters related to the electronic transmission of the structure and the influence of these parameters on the current voltage characteristic are investigated, bringing insights on critical processes to optimize in double resonant tunneling barriers applied to hot carrier solar cells.
Capsicum annuum dehydrin, an osmotic-stress gene in hot pepper plants.
Chung, Eunsook; Kim, Soo-Yong; Yi, So Young; Choi, Doil
2003-06-30
Osmotic stress-related genes were selected from an EST database constructed from 7 cDNA libraries from different tissues of the hot pepper. A full-length cDNA of Capsicum annuum dehydrin (Cadhn), a late embryogenesis abundant (lea) gene, was selected from the 5' single pass sequenced cDNA clones and sequenced. The deduced polypeptide has 87% identity with potato dehydrin C17, but very little identity with the dehydrin genes of other organisms. It contains a serine-tract (S-segment) and 3 conserved lysine-rich domains (K-segments). Southern blot analysis showed that 2 copies are present in the hot pepper genome. Cadhn was induced by osmotic stress in leaf tissues as well as by the application of abscisic acid. The RNA was most abundant in green fruit. The expression of several osmotic stress-related genes was examined and Cadhn proved to be the most abundantly expressed of these in response to osmotic stress.
Maner, Jonathon A; Mauney, Daniel T; Duncan, Michael A
2015-11-19
Ag(+)(benzene) complexes are generated in the gas phase by laser vaporization and mass selected in a time-of-flight spectrometer. UV laser excitation at either 355 or 266 nm results in dissociative charge transfer (DCT), leading to neutral silver atom and benzene cation products. Kinetic energy release in translationally hot benzene cations is detected using a new instrument designed for photofragment imaging of mass-selected ions. Velocity-map imaging and slice imaging techniques are employed. In addition to the expected translational energy release, DCT of Ag(+)(benzene) produces a distribution of internally hot benzene cations. Compared with experiments at 355 nm, 266 nm excitation produces only slightly higher translational excitation and a much greater fraction of internally hot benzene ions. The maximum kinetic energy release in the photodissociation sets an upper limit on the Ag(+)(benzene) dissociation energy of 32.8 (+1.4/-1.5) kcal/mol.