Distinct behavioural profiles in frontotemporal dementia and semantic dementia

PubMed Central

Snowden, J; Bathgate, D; Varma, A; Blackshaw, A; Gibbons, Z; Neary, D

2001-01-01

OBJECTIVE—To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change.
METHODS—An informant based semistructured behavioural interview, covering the domains of basic and social emotions, social and personal behaviour, sensory behaviour, eating and oral behaviour, repetitive behaviours, rituals, and compulsions, was administered to carers of 41 patients with semantic dementia and with apathetic (FTD-A) and disinhibited (FTD-D) forms of frontotemporal dementia.
RESULTS—Consistent with prediction, emotional changes differentiated FTD from semantic dementia. Whereas lack of emotional response was pervasive in FTD, it was more selective in semantic dementia, affecting particularly the capacity to show fear. Social avoidance occurred more often in FTD and social seeking in semantic dementia. Patients with FTD showed reduced response to pain, whereas patients with semantic dementia more often showed exaggerated reactions to sensory stimuli. Gluttony and indiscriminate eating were characteristic of FTD, whereas patients with semantic dementia were more likely to exhibit food fads. Hyperorality, involving inedible objects, was unrelated to gluttony, indicating different underlying mechanisms. Repetitive behaviours were common in both FTD and semantic dementia, but had a more compulsive quality in semantic dementia. Behavioural differences were greater between semantic dementia and FTD-A than FTD-D. A logistic regression analysis indicated that emotional and repetitive, compulsive behaviours discriminated FTD from semantic dementia with 97% accuracy.
CONCLUSION—The findings confirm predictions regarding behavioural differences in frontotemporal and semantic dementia and point to differential roles of the frontal and temporal lobes in affect, social functioning, eating, and compulsive behaviour.

 PMID:11181853

Neural differentiation of lexico-syntactic categories or semantic features? event-related potential evidence for both.

PubMed

Kellenbach, Marion L; Wijers, Albertus A; Hovius, Marjolijn; Mulder, Juul; Mulder, Gijsbertus

2002-05-15

Event-related potentials (ERPs) were used to investigate whether processing differences between nouns and verbs can be accounted for by the differential salience of visual-perceptual and motor attributes in their semantic specifications. Three subclasses of nouns and verbs were selected, which differed in their semantic attribute composition (abstract, high visual, high visual and motor). Single visual word presentation with a recognition memory task was used. While multiple robust and parallel ERP effects were observed for both grammatical class and attribute type, there were no interactions between these. This pattern of effects provides support for lexical-semantic knowledge being organized in a manner that takes account both of category-based (grammatical class) and attribute-based distinctions.

Attitudes toward Younger and Older Adults: The German Aging Semantic Differential

ERIC Educational Resources Information Center

Gluth, Sebastian; Ebner, Natalie C.; Schmiedek, Florian

2010-01-01

The present study used the German Aging Semantic Differential (ASD) to assess attitudes toward younger and older adults in a heterogeneous sample of n = 151 younger and n = 143 older adults. The questionnaire was administered in two versions, one referring to the evaluation of younger adults, the other to the evaluation of older adults.…

The Case for the Semantic Differential in Organizational and Business Research

ERIC Educational Resources Information Center

Piotrowski, Chris; Guyette, Roger W., Jr.

2010-01-01

Attitude measurement has been and continues to be a central component in the field of social psychology. The semantic differential technique has proven to be a well-respected measuring device of attitudes since the 1960s, particularly in the social sciences. Given the importance of attitudes in the business world with reference to preferences in…

Levels of Processing and the Cue-Dependent Nature of Recollection

ERIC Educational Resources Information Center

Mulligan, Neil W.; Picklesimer, Milton

2012-01-01

Dual-process models differentiate between two bases of memory, recollection and familiarity. It is routinely claimed that deeper, semantic encoding enhances recollection relative to shallow, non-semantic encoding, and that recollection is largely a product of semantic, elaborative rehearsal. The present experiments show that this is not always the…

The Relationship Between Responses to Science Concepts on a Semantic Differential Instrument and Achievement in Freshman Physics and Chemistry.

ERIC Educational Resources Information Center

Rothman, Arthur Israel

Students taking freshman physics and freshman chemistry at The State University of New York at Buffalo (SUNYAB) were administered a science-related semantic differential instrument. This same test was administered to physics and chemistry graduate students from SUNYAB and the University of Rochester. A scoring procedure was developed which…

The Use of the Semantic Differential Method in Assessing Attitudes and Predicting Final Grades in a Gross Anatomy Course.

ERIC Educational Resources Information Center

Lee, Mickey M.; And Others

Whether a change in dental students' attitudes toward three preselected concepts would occur as a result of a traditionally difficult dental education course as measured by the semantic differential method is determined. This study attempted to determine the predictive value of a student's attitudes in determining his/her final grade. The sample…

Attention to Distinct Goal-relevant Features Differentially Guides Semantic Knowledge Retrieval.

PubMed

Hanson, Gavin K; Chrysikou, Evangelia G

2017-07-01

A critical aspect of conceptual knowledge is the selective activation of goal-relevant aspects of meaning. Although the contributions of ventrolateral prefrontal and posterior temporal areas to semantic cognition are well established, the precise role of posterior parietal cortex in semantic control remains unknown. Here, we examined whether this region modulates attention to goal-relevant features within semantic memory according to the same principles that determine the salience of task-relevant object properties during visual attention. Using multivoxel pattern analysis, we decoded attentional referents during a semantic judgment task, in which participants matched an object cue to a target according to concrete (i.e., color, shape) or abstract (i.e., function, thematic context) semantic features. The goal-relevant semantic feature participants attended to (e.g., color or shape, function or theme) could be decoded from task-associated cortical activity with above-chance accuracy, a pattern that held for both concrete and abstract semantic features. A Bayesian confusion matrix analysis further identified differential contributions to representing attentional demands toward specific object properties across lateral prefrontal, posterior temporal, and inferior parietal regions, with the dorsolateral pFC supporting distinctions between higher-order properties and the left intraparietal sulcus being the only region supporting distinctions across all semantic features. These results are the first to demonstrate that patterns of neural activity in the parietal cortex are sensitive to which features of a concept are attended to, thus supporting the contributions of posterior parietal cortex to semantic control.

Design-Based Guidelines for the Semantic Perception of Emergency Signs

ERIC Educational Resources Information Center

Chang, Chin-Wei; Hsiao, Hung-Yi; Tang, Chieh-Hsin; Chuang, Ying-Ji; Lin, Ching-Yuan

2010-01-01

The current study applies semantic differential to explore the semantic perception of emergency signs, in an attempt to analyze the meanings of emergency signs in regard to the psychological exigencies of the general public. The results indicate that problems concerning recognition accuracy have been observed, but also that the evaluation of the…

An Analysis of Perceptions and Attitudes Toward the Concepts "Disabled" and "Handicapped" and the Effects of Pre-Structured Definition Upon the Concepts.

ERIC Educational Resources Information Center

Ianacone, Robert N.; Stodden, Robert A.

The semantic differential technique was used in a study involving 40 undergraduate trainees in the area of special education to analyze the concepts "disabled" and "handicapped" and the effects of structured knowledge or definition on the participants' perceptions of and attitudes toward the concepts. The Semantic differential consisted of bipolar…

Preliminary Exploration of the Chromatic Differential: The Measurement of the Meaning of Color.

ERIC Educational Resources Information Center

Johnson, Edward A.

A study investigated the reciprocal relationship between colors and semantic terms--just as certain semantic terms elicit thoughts of particular colors, so those colors may also elicit their reciprocal semantic terms. Twenty-six students were each shown 18 words: 3 each of bipolar pairs that expressed evaluation, activity, or potency. The students…

Complexity and Hemispheric Abilities: Evidence for a Differential Impact on Semantics and Phonology

ERIC Educational Resources Information Center

Tremblay, Tania; Monetta, Laura; Joanette, Yves

2009-01-01

The main goal of this study was to determine whether the phonological and semantic processing of words are similarly influenced by an increase in processing complexity. Thirty-six French-speaking young adults performed both semantic and phonological word judgment tasks, using a divided visual field procedure. The phonological complexity of words…

Differential pattern of semantic memory organization between bipolar I and II disorders.

PubMed

Chang, Jae Seung; Choi, Sungwon; Ha, Kyooseob; Ha, Tae Hyon; Cho, Hyun Sang; Choi, Jung Eun; Cha, Boseok; Moon, Eunsoo

2011-06-01

Semantic cognition is one of the key factors in psychosocial functioning. The aim of this study was to explore the differences in pattern of semantic memory organization between euthymic patients with bipolar I and II disorders using the category fluency task. Study participants included 23 euthymic subjects with bipolar I disorder, 23 matched euthymic subjects with bipolar II disorder and 23 matched control subjects. All participants were assessed for verbal learning, recall, learning strategies, and fluency. The combined methods of hierarchical clustering and multidimensional scaling were used to compare the pattern of semantic memory organization among the three groups. Quantitative measures of verbal learning, recall, learning strategies, and fluency did not differ between the three groups. A two-cluster structure of semantic memory organization was identified for the three groups. Semantic structure was more disorganized in the bipolar I disorder group compared to the bipolar II disorder. In addition, patients with bipolar II disorder used less elaborate strategies of semantic memory organization than those of controls. Compared to healthy controls, strategies for categorization in semantic memory appear to be less knowledge-based in patients with bipolar disorders. A differential pattern of semantic memory organization between bipolar I and II disorders indicates a higher risk of cognitive abnormalities in patients with bipolar I disorder compared to patients with bipolar II disorder. Exploring qualitative nature of neuropsychological domains may provide an explanatory insight into the characteristic behaviors of patients with bipolar disorders. Copyright © 2011 Elsevier Inc. All rights reserved.

A systematic approach to advanced cockpit warning systems for air transport operations: Line pilot preferences

NASA Technical Reports Server (NTRS)

Williams, D. H.; Simpson, C. A.

1976-01-01

Line pilots (fifty captains, first officers, and flight engineers) from 8 different airlines were administered a structured questionnaire relating to future warning system design and solutions to current warning system problems. This was followed by a semantic differential to obtain a factor analysis of 18 different cockpit warning signals on scales such as informative/distracting, annoying/soothing. Half the pilots received a demonstration of the experimental text and voice synthesizer warning systems before answering the questionnaire and the semantic differential. A control group answered the questionnaire and the semantic differential first, thus providing a check for the stability of pilot preferences with and without actual exposure to experimental systems. Generally, the preference data obtained revealed much consistency and strong agreement among line pilots concerning advance cockpit warning system design.

Differential Phonological and Semantic Modulation of Neurophysiological Responses to Visual Word Recognition.

PubMed

Drakesmith, Mark; El-Deredy, Wael; Welbourne, Stephen

2015-01-01

Reading words for meaning relies on orthographic, phonological and semantic processing. The triangle model implicates a direct orthography-to-semantics pathway and a phonologically mediated orthography-to-semantics pathway, which interact with each other. The temporal evolution of processing in these routes is not well understood, although theoretical evidence predicts early phonological processing followed by interactive phonological and semantic processing. This study used electroencephalography-event-related potential (ERP) analysis and magnetoencephalography (MEG) source localisation to identify temporal markers and the corresponding neural generators of these processes in early (∼200 ms) and late (∼400 ms) neurophysiological responses to visual words, pseudowords and consonant strings. ERP showed an effect of phonology but not semantics in both time windows, although at ∼400 ms there was an effect of stimulus familiarity. Phonological processing at ~200 ms was localised to the left occipitotemporal cortex and the inferior frontal gyrus. At 400 ms, there was continued phonological processing in the inferior frontal gyrus and additional semantic processing in the anterior temporal cortex. There was also an area in the left temporoparietal junction which was implicated in both phonological and semantic processing. In ERP, the semantic response at ∼400 ms appeared to be masked by concurrent processes relating to familiarity, while MEG successfully differentiated these processes. The results support the prediction of early phonological processing followed by an interaction of phonological and semantic processing during word recognition. Neuroanatomical loci of these processes are consistent with previous neuropsychological and functional magnetic resonance imaging studies. The results also have implications for the classical interpretation of N400-like responses as markers for semantic processing.

Semantic Differential as One of the Research Tools Suitable for Establishing the Attitudes of Pupils to Old Age and Seniors

ERIC Educational Resources Information Center

Divilová, Sona

2016-01-01

The paper presents the results of the pre-research conducted under the project entitled "Seniors in the Eyes of Children". The main objective of the project was to create and test a research tool in order to establish what the attitudes of pupils to old age and seniors were. Semantic differential was chosen for these purposes. Semantic…

Dementias show differential physiological responses to salient sounds.

PubMed

Fletcher, Phillip D; Nicholas, Jennifer M; Shakespeare, Timothy J; Downey, Laura E; Golden, Hannah L; Agustus, Jennifer L; Clark, Camilla N; Mummery, Catherine J; Schott, Jonathan M; Crutch, Sebastian J; Warren, Jason D

2015-01-01

Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals, looming sounds, in canonical dementia syndromes. We manipulated tones using intensity cues to create percepts of salient approaching ("looming") or less salient withdrawing sounds. Pupil dilatation responses and behavioral rating responses to these stimuli were compared in patients fulfilling consensus criteria for dementia syndromes (semantic dementia, n = 10; behavioral variant frontotemporal dementia, n = 16, progressive nonfluent aphasia, n = 12; amnestic Alzheimer's disease, n = 10) and a cohort of 26 healthy age-matched individuals. Approaching sounds were rated as more salient than withdrawing sounds by healthy older individuals but this behavioral response to salience did not differentiate healthy individuals from patients with dementia syndromes. Pupil responses to approaching sounds were greater than responses to withdrawing sounds in healthy older individuals and in patients with semantic dementia: this differential pupil response was reduced in patients with progressive nonfluent aphasia and Alzheimer's disease relative both to the healthy control and semantic dementia groups, and did not correlate with nonverbal auditory semantic function. Autonomic responses to auditory salience are differentially affected by dementias and may constitute a novel biomarker of these diseases.

Dementias show differential physiological responses to salient sounds

PubMed Central

Fletcher, Phillip D.; Nicholas, Jennifer M.; Shakespeare, Timothy J.; Downey, Laura E.; Golden, Hannah L.; Agustus, Jennifer L.; Clark, Camilla N.; Mummery, Catherine J.; Schott, Jonathan M.; Crutch, Sebastian J.; Warren, Jason D.

2015-01-01

Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals, looming sounds, in canonical dementia syndromes. We manipulated tones using intensity cues to create percepts of salient approaching (“looming”) or less salient withdrawing sounds. Pupil dilatation responses and behavioral rating responses to these stimuli were compared in patients fulfilling consensus criteria for dementia syndromes (semantic dementia, n = 10; behavioral variant frontotemporal dementia, n = 16, progressive nonfluent aphasia, n = 12; amnestic Alzheimer's disease, n = 10) and a cohort of 26 healthy age-matched individuals. Approaching sounds were rated as more salient than withdrawing sounds by healthy older individuals but this behavioral response to salience did not differentiate healthy individuals from patients with dementia syndromes. Pupil responses to approaching sounds were greater than responses to withdrawing sounds in healthy older individuals and in patients with semantic dementia: this differential pupil response was reduced in patients with progressive nonfluent aphasia and Alzheimer's disease relative both to the healthy control and semantic dementia groups, and did not correlate with nonverbal auditory semantic function. Autonomic responses to auditory salience are differentially affected by dementias and may constitute a novel biomarker of these diseases. PMID:25859194

Frontal lobe damage impairs process and content in semantic memory: evidence from category-specific effects in progressive non-fluent aphasia.

PubMed

Reilly, Jamie; Rodriguez, Amy D; Peelle, Jonathan E; Grossman, Murray

2011-06-01

Portions of left inferior frontal cortex have been linked to semantic memory both in terms of the content of conceptual representation (e.g., motor aspects in an embodied semantics framework) and the cognitive processes used to access these representations (e.g., response selection). Progressive non-fluent aphasia (PNFA) is a neurodegenerative condition characterized by progressive atrophy of left inferior frontal cortex. PNFA can, therefore, provide a lesion model for examining the impact of frontal lobe damage on semantic processing and content. In the current study we examined picture naming in a cohort of PNFA patients across a variety of semantic categories. An embodied approach to semantic memory holds that sensorimotor features such as self-initiated action may assume differential importance for the representation of manufactured artifacts (e.g., naming hand tools). Embodiment theories might therefore predict that patients with frontal damage would be differentially impaired on manufactured artifacts relative to natural kinds, and this prediction was borne out. We also examined patterns of naming errors across a wide range of semantic categories and found that naming error distributions were heterogeneous. Although PNFA patients performed worse overall on naming manufactured artifacts, there was no reliable relationship between anomia and manipulability across semantic categories. These results add to a growing body of research arguing against a purely sensorimotor account of semantic memory, suggesting instead a more nuanced balance of process and content in how the brain represents conceptual knowledge. Copyright © 2010 Elsevier Srl. All rights reserved.

The Influence of rTMS over Prefrontal and Motor Areas in a Morphological Task: Grammatical vs. Semantic Effects

ERIC Educational Resources Information Center

LoGerfo, Emanuele; Oliveri, Massimiliano; Torriero, Sara; Salerno, Silvia; Koch, Giacomo; Caltagirone, Carlo

2008-01-01

We investigated the differential role of two frontal regions in the processing of grammatical and semantic knowledge. Given the documented specificity of the prefrontal cortex for the grammatical class of verbs, and of the primary motor cortex for the semantic class of action words, we sought to investigate whether the prefrontal cortex is also…

Differential cognitive processing of Kanji and Kana words: do orthographic and semantic codes function in parallel in word matching task.

PubMed

Kawakami, A; Hatta, T; Kogure, T

2001-12-01

Relative engagements of the orthographic and semantic codes in Kanji and Hiragana word recognition were investigated. In Exp. 1, subjects judged whether the pairs of Kanji words (prime and target) presented sequentially were physically identical to each other in the word condition. In the sentence condition, subjects decided whether the target word was valid for the prime sentence presented in advance. The results showed that the response times to the target swords orthographically similar (to the prime) were significantly slower than to semantically related target words in the word condition and that this was also the case in the sentence condition. In Exp. 2, subjects judged whether the target word written in Hiragana was physically identical to the prime word in the word condition. In the sentence condition, subjects decided if the target word was valid for the previously presented prime sentence. Analysis indicated that response times to orthographically similar words were slower than to semantically related words in the word condition but not in the sentence condition wherein the response times to the semantically and orthographically similar words were largely the same. Based on these results, differential contributions of orthographic and semantic codes in cognitive processing of Japanese Kanji and Hiragana words was discussed.

The word processing deficit in semantic dementia: all categories are equal, but some categories are more equal than others.

PubMed

Pulvermüller, Friedemann; Cooper-Pye, Elisa; Dine, Clare; Hauk, Olaf; Nestor, Peter J; Patterson, Karalyn

2010-09-01

It has been claimed that semantic dementia (SD), the temporal variant of fronto-temporal dementia, is characterized by an across-the-board deficit affecting all types of conceptual knowledge. We here confirm this generalized deficit but also report differential degrees of impairment in processing specific semantic word categories in a case series of SD patients (N = 11). Within the domain of words with strong visually grounded meaning, the patients' lexical decision accuracy was more impaired for color-related than for form-related words. Likewise, within the domain of action verbs, the patients' performance was worse for words referring to face movements and speech acts than for words semantically linked to actions performed with the hand and arm. Psycholinguistic properties were matched between the stimulus groups entering these contrasts; an explanation for the differential degrees of impairment must therefore involve semantic features of the words in the different conditions. Furthermore, this specific pattern of deficits cannot be captured by classic category distinctions such as nouns versus verbs or living versus nonliving things. Evidence from previous neuroimaging research indicates that color- and face/speech-related words, respectively, draw most heavily on anterior-temporal and inferior-frontal areas, the structures most affected in SD. Our account combines (a) the notion of an anterior-temporal amodal semantic "hub" to explain the profound across-the-board deficit in SD word processing, with (b) a semantic topography model of category-specific circuits whose cortical distributions reflect semantic features of the words and concepts represented.

The Semantic Network at Work and Rest: Differential Connectivity of Anterior Temporal Lobe Subregions.

PubMed

Jackson, Rebecca L; Hoffman, Paul; Pobric, Gorana; Lambon Ralph, Matthew A

2016-02-03

The anterior temporal lobe (ATL) makes a critical contribution to semantic cognition. However, the functional connectivity of the ATL and the functional network underlying semantic cognition has not been elucidated. In addition, subregions of the ATL have distinct functional properties and thus the potential differential connectivity between these subregions requires investigation. We explored these aims using both resting-state and active semantic task data in humans in combination with a dual-echo gradient echo planar imaging (EPI) paradigm designed to ensure signal throughout the ATL. In the resting-state analysis, the ventral ATL (vATL) and anterior middle temporal gyrus (MTG) were shown to connect to areas responsible for multimodal semantic cognition, including bilateral ATL, inferior frontal gyrus, medial prefrontal cortex, angular gyrus, posterior MTG, and medial temporal lobes. In contrast, the anterior superior temporal gyrus (STG)/superior temporal sulcus was connected to a distinct set of auditory and language-related areas, including bilateral STG, precentral and postcentral gyri, supplementary motor area, supramarginal gyrus, posterior temporal cortex, and inferior and middle frontal gyri. Complementary analyses of functional connectivity during an active semantic task were performed using a psychophysiological interaction (PPI) analysis. The PPI analysis highlighted the same semantic regions suggesting a core semantic network active during rest and task states. This supports the necessity for semantic cognition in internal processes occurring during rest. The PPI analysis showed additional connectivity of the vATL to regions of occipital and frontal cortex. These areas strongly overlap with regions found to be sensitive to executively demanding, controlled semantic processing. Previous studies have shown that semantic cognition depends on subregions of the anterior temporal lobe (ATL). However, the network of regions functionally connected to these subregions has not been demarcated. Here, we show that these ventrolateral anterior temporal subregions form part of a network responsible for semantic processing during both rest and an explicit semantic task. This demonstrates the existence of a core functional network responsible for multimodal semantic cognition regardless of state. Distinct connectivity is identified in the superior ATL, which is connected to auditory and language areas. Understanding the functional connectivity of semantic cognition allows greater understanding of how this complex process may be performed and the role of distinct subregions of the anterior temporal cortex. Copyright © 2016 Jackson et al.

The Semantic Network at Work and Rest: Differential Connectivity of Anterior Temporal Lobe Subregions

PubMed Central

Jackson, Rebecca L.; Hoffman, Paul; Pobric, Gorana

2016-01-01

The anterior temporal lobe (ATL) makes a critical contribution to semantic cognition. However, the functional connectivity of the ATL and the functional network underlying semantic cognition has not been elucidated. In addition, subregions of the ATL have distinct functional properties and thus the potential differential connectivity between these subregions requires investigation. We explored these aims using both resting-state and active semantic task data in humans in combination with a dual-echo gradient echo planar imaging (EPI) paradigm designed to ensure signal throughout the ATL. In the resting-state analysis, the ventral ATL (vATL) and anterior middle temporal gyrus (MTG) were shown to connect to areas responsible for multimodal semantic cognition, including bilateral ATL, inferior frontal gyrus, medial prefrontal cortex, angular gyrus, posterior MTG, and medial temporal lobes. In contrast, the anterior superior temporal gyrus (STG)/superior temporal sulcus was connected to a distinct set of auditory and language-related areas, including bilateral STG, precentral and postcentral gyri, supplementary motor area, supramarginal gyrus, posterior temporal cortex, and inferior and middle frontal gyri. Complementary analyses of functional connectivity during an active semantic task were performed using a psychophysiological interaction (PPI) analysis. The PPI analysis highlighted the same semantic regions suggesting a core semantic network active during rest and task states. This supports the necessity for semantic cognition in internal processes occurring during rest. The PPI analysis showed additional connectivity of the vATL to regions of occipital and frontal cortex. These areas strongly overlap with regions found to be sensitive to executively demanding, controlled semantic processing. SIGNIFICANCE STATEMENT Previous studies have shown that semantic cognition depends on subregions of the anterior temporal lobe (ATL). However, the network of regions functionally connected to these subregions has not been demarcated. Here, we show that these ventrolateral anterior temporal subregions form part of a network responsible for semantic processing during both rest and an explicit semantic task. This demonstrates the existence of a core functional network responsible for multimodal semantic cognition regardless of state. Distinct connectivity is identified in the superior ATL, which is connected to auditory and language areas. Understanding the functional connectivity of semantic cognition allows greater understanding of how this complex process may be performed and the role of distinct subregions of the anterior temporal cortex. PMID:26843633

Potential role of monkey inferior parietal neurons coding action semantic equivalences as precursors of parts of speech.

PubMed

Yamazaki, Yumiko; Yokochi, Hiroko; Tanaka, Michio; Okanoya, Kazuo; Iriki, Atsushi

2010-01-01

The anterior portion of the inferior parietal cortex possesses comprehensive representations of actions embedded in behavioural contexts. Mirror neurons, which respond to both self-executed and observed actions, exist in this brain region in addition to those originally found in the premotor cortex. We found that parietal mirror neurons responded differentially to identical actions embedded in different contexts. Another type of parietal mirror neuron represents an inverse and complementary property of responding equally to dissimilar actions made by itself and others for an identical purpose. Here, we propose a hypothesis that these sets of inferior parietal neurons constitute a neural basis for encoding the semantic equivalence of various actions across different agents and contexts. The neurons have mirror neuron properties, and they encoded generalization of agents, differentiation of outcomes, and categorization of actions that led to common functions. By integrating the activities of these mirror neurons with various codings, we further suggest that in the ancestral primates' brains, these various representations of meaningful action led to the gradual establishment of equivalence relations among the different types of actions, by sharing common action semantics. Such differential codings of the components of actions might represent precursors to the parts of protolanguage, such as gestural communication, which are shared among various members of a society. Finally, we suggest that the inferior parietal cortex serves as an interface between this action semantics system and other higher semantic systems, through common structures of action representation that mimic language syntax.

Potential role of monkey inferior parietal neurons coding action semantic equivalences as precursors of parts of speech

PubMed Central

Yamazaki, Yumiko; Yokochi, Hiroko; Tanaka, Michio; Okanoya, Kazuo; Iriki, Atsushi

2010-01-01

The anterior portion of the inferior parietal cortex possesses comprehensive representations of actions embedded in behavioural contexts. Mirror neurons, which respond to both self-executed and observed actions, exist in this brain region in addition to those originally found in the premotor cortex. We found that parietal mirror neurons responded differentially to identical actions embedded in different contexts. Another type of parietal mirror neuron represents an inverse and complementary property of responding equally to dissimilar actions made by itself and others for an identical purpose. Here, we propose a hypothesis that these sets of inferior parietal neurons constitute a neural basis for encoding the semantic equivalence of various actions across different agents and contexts. The neurons have mirror neuron properties, and they encoded generalization of agents, differentiation of outcomes, and categorization of actions that led to common functions. By integrating the activities of these mirror neurons with various codings, we further suggest that in the ancestral primates' brains, these various representations of meaningful action led to the gradual establishment of equivalence relations among the different types of actions, by sharing common action semantics. Such differential codings of the components of actions might represent precursors to the parts of protolanguage, such as gestural communication, which are shared among various members of a society. Finally, we suggest that the inferior parietal cortex serves as an interface between this action semantics system and other higher semantic systems, through common structures of action representation that mimic language syntax. PMID:20119879

Language Networks Associated with Computerized Semantic Indices

PubMed Central

Pakhomov, Serguei V. S.; Jones, David T.; Knopman, David S.

2014-01-01

Tests of generative semantic verbal fluency are widely used to study organization and representation of concepts in the human brain. Previous studies demonstrated that clustering and switching behavior during verbal fluency tasks is supported by multiple brain mechanisms associated with semantic memory and executive control. Previous work relied on manual assessments of semantic relatedness between words and grouping of words into semantic clusters. We investigated a computational linguistic approach to measuring the strength of semantic relatedness between words based on latent semantic analysis of word co-occurrences in a subset of a large online encyclopedia. We computed semantic clustering indices and compared them to brain network connectivity measures obtained with task-free fMRI in a sample consisting of healthy participants and those differentially affected by cognitive impairment. We found that semantic clustering indices were associated with brain network connectivity in distinct areas including fronto-temporal, fronto-parietal and fusiform gyrus regions. This study shows that computerized semantic indices complement traditional assessments of verbal fluency to provide a more complete account of the relationship between brain and verbal behavior involved organization and retrieval of lexical information from memory. PMID:25315785

Buckets: Aggregative, Intelligent Agents for Publishing

NASA Technical Reports Server (NTRS)

Nelson, Michael L.; Maly, Kurt; Shen, Stewart N. T.; Zubair, Mohammad

1998-01-01

Buckets are an aggregative, intelligent construct for publishing in digital libraries. The goal of research projects is to produce information. This information is often instantiated in several forms, differentiated by semantic types (report, software, video, datasets, etc.). A given semantic type can be further differentiated by syntactic representations as well (PostScript version, PDF version, Word version, etc.). Although the information was created together and subtle relationships can exist between them, different semantic instantiations are generally segregated along currently obsolete media boundaries. Reports are placed in report archives, software might go into a software archive, but most of the data and supporting materials are likely to be kept in informal personal archives or discarded altogether. Buckets provide an archive-independent container construct in which all related semantic and syntactic data types and objects can be logically grouped together, archived, and manipulated as a single object. Furthermore, buckets are active archival objects and can communicate with each other, people, or arbitrary network services.

Development of an Instrument for Measuring Clinicians’ Power Perceptions in the Workplace

PubMed Central

Bartos, Christa E.; Fridsma, Douglas B.; Butler, Brian S.; Penrod, Louis E.; Becich, Michael J.; Crowley, Rebecca S.

2008-01-01

We report on the development of an instrument to measure clinicians’ perceptions of their personal power in the workplace in relation to resistance to computerized physician order entry (CPOE). The instrument is based on French and Raven’s six bases of social power and uses a semantic differential methodology. A measurement study was conducted to determine the reliability and validity of the survey. The survey was administered online and distributed via a URL by email to 19 physicians, nurses, and health unit coordinators from a university hospital. Acceptable reliability was achieved by removing or moving some semantic differential word pairs used to represent the six power bases (alpha range from 0.76–0.89). The Semantic Differential Power Perception (SDPP) survey validity was tested against an already validated instrument and found to be acceptable (correlation range from 0.51–0.81). The SDPP survey instrument was determined to be both reliable and valid. PMID:18375189

Semantic dementia Brazilian study of nineteen cases

PubMed Central

Senaha, Mirna Lie Hosogi; Caramelli, Paulo; Porto, Claudia Sellitto; Nitrini, Ricardo

2007-01-01

The term semantic dementia was devised by Snowden et al. in 1989 and nowadays, the semantic dementia syndrome is recognized as one of the clinical forms of frontotemporal lobar degeneration (FTLD) and is characterized by a language semantic disturbance associated to non-verbal semantic memory impairment. Objectives The aim of this study was to describe a Brazilian sample of 19 semantic dementia cases, emphasizing the clinical characteristics important for differential diagnosis of this syndrome. Methods Nineteen cases with semantic dementia were evaluated between 1999 and 2007. All patients were submitted to neurological evaluation, neuroimaging exams and cognitive, language and semantic memory evaluation. Results All patients presented fluent spontaneous speech, preservation of syntactic and phonological aspects of the language, word-finding difficulty, semantic paraphasias, word comprehension impairment, low performance in visual confrontation naming tasks, impairment on tests of non-verbal semantic memory and preservation of autobiographical memory and visuospatial skills. Regarding radiological investigations, temporal lobe atrophy and/or hypoperfusion were found in all patients. Conclusions The cognitive, linguistic and of neuroimaging data in our case series corroborate other studies showing that semantic dementia constitutes a syndrome with well defined clinical characteristics associated to temporal lobe atrophy. PMID:29213413

Premorbid expertise produces category-specific impairment in a domain-general semantic disorder.

PubMed

Jefferies, Elizabeth; Rogers, Timothy T; Ralph, Matthew A Lambon

2011-10-01

For decades, category-specific semantic impairment - i.e., better comprehension of items from one semantic category than another - has been the driving force behind many claims about the organisation of conceptual knowledge in the brain. Double dissociations between patients with category-specific disorders are widely interpreted as showing that different conceptual domains are necessarily supported by functionally independent systems. We show that, to the contrary, even strong or classical dissociations can also arise from individual differences in premorbid expertise. We examined two patients with global and progressive semantic degradation who, unusually, had known areas of premorbid expertise. Patient 1, a former automotive worker, showed selective preservation of car knowledge, whereas Patient 2, a former botanist, showed selective preservation of information about plants. In non-expert domains, these patients showed the typical pattern: i.e., an inability to differentiate between highly similar concepts (e.g., rose and daisy), but retention of broader distinctions (e.g., between rose and cat). Parallel distributed processing (PDP) models of semantic cognition show that expertise in a particular domain increases the differentiation of specific-level concepts, such that the semantic distance between these items resembles non-expert basic-level distinctions. We propose that these structural changes interact with global semantic degradation, particularly when expert knowledge is acquired early and when exposure to expert concepts continues during disease progression. Therefore, category-specific semantic impairment can arise from at least two distinct mechanisms: damage to representations that are critical for a particular category (e.g., knowledge of hand shape and action for the category 'tools') and differences in premorbid experience. Copyright © 2011 Elsevier Ltd. All rights reserved.

Event Congruency and Episodic Encoding: A Developmental fMRI Study

ERIC Educational Resources Information Center

Maril, Anat; Avital, Rinat; Reggev, Niv; Zuckerman, Maya; Sadeh, Talya; Sira, Liat Ben; Livneh, Neta

2011-01-01

A known contributor to adults' superior memory performance compared to children is their differential reliance on an existing knowledge base. Compared to those of adults, children's semantic networks are less accessible and less established, a difference that is also thought to contribute to children's relative resistance to semantically related…

Differential Lexical Predictors of Reading Comprehension in Fourth Graders

ERIC Educational Resources Information Center

Swart, Nicole M.; Muijselaar, Marloes M. L.; Steenbeek-Planting, Esther G.; Droop, Mienke; de Jong, Peter F.; Verhoeven, L.

2017-01-01

The mental lexicon plays a central role in reading comprehension (Perfetti & Stafura, 2014). It encompasses the number of lexical entries in spoken and written language (vocabulary breadth), the semantic quality of these entries (vocabulary depth), and the connection strength between lexical representations (semantic relatedness); as such, it…

Development of Category-based Induction and Semantic Knowledge

ERIC Educational Resources Information Center

Fisher, Anna V.; Godwin, Karrie E.; Matlen, Bryan J.; Unger, Layla

2015-01-01

Category-based induction is a hallmark of mature cognition; however, little is known about its origins. This study evaluated the hypothesis that category-based induction is related to semantic development. Computational studies suggest that early on there is little differentiation among concepts, but learning and development lead to increased…

Differential Processing of Thematic and Categorical Conceptual Relations in Spoken Word Production

ERIC Educational Resources Information Center

de Zubicaray, Greig I.; Hansen, Samuel; McMahon, Katie L.

2013-01-01

Studies of semantic context effects in spoken word production have typically distinguished between categorical (or taxonomic) and associative relations. However, associates tend to confound semantic features or morphological representations, such as whole-part relations and compounds (e.g., BOAT-anchor, BEE-hive). Using a picture-word interference…

Developing a semantic web model for medical differential diagnosis recommendation.

PubMed

Mohammed, Osama; Benlamri, Rachid

2014-10-01

In this paper we describe a novel model for differential diagnosis designed to make recommendations by utilizing semantic web technologies. The model is a response to a number of requirements, ranging from incorporating essential clinical diagnostic semantics to the integration of data mining for the process of identifying candidate diseases that best explain a set of clinical features. We introduce two major components, which we find essential to the construction of an integral differential diagnosis recommendation model: the evidence-based recommender component and the proximity-based recommender component. Both approaches are driven by disease diagnosis ontologies designed specifically to enable the process of generating diagnostic recommendations. These ontologies are the disease symptom ontology and the patient ontology. The evidence-based diagnosis process develops dynamic rules based on standardized clinical pathways. The proximity-based component employs data mining to provide clinicians with diagnosis predictions, as well as generates new diagnosis rules from provided training datasets. This article describes the integration between these two components along with the developed diagnosis ontologies to form a novel medical differential diagnosis recommendation model. This article also provides test cases from the implementation of the overall model, which shows quite promising diagnostic recommendation results.

Language networks associated with computerized semantic indices.

PubMed

Pakhomov, Serguei V S; Jones, David T; Knopman, David S

2015-01-01

Tests of generative semantic verbal fluency are widely used to study organization and representation of concepts in the human brain. Previous studies demonstrated that clustering and switching behavior during verbal fluency tasks is supported by multiple brain mechanisms associated with semantic memory and executive control. Previous work relied on manual assessments of semantic relatedness between words and grouping of words into semantic clusters. We investigated a computational linguistic approach to measuring the strength of semantic relatedness between words based on latent semantic analysis of word co-occurrences in a subset of a large online encyclopedia. We computed semantic clustering indices and compared them to brain network connectivity measures obtained with task-free fMRI in a sample consisting of healthy participants and those differentially affected by cognitive impairment. We found that semantic clustering indices were associated with brain network connectivity in distinct areas including fronto-temporal, fronto-parietal and fusiform gyrus regions. This study shows that computerized semantic indices complement traditional assessments of verbal fluency to provide a more complete account of the relationship between brain and verbal behavior involved organization and retrieval of lexical information from memory. Copyright © 2014 Elsevier Inc. All rights reserved.

The semantic distance task: Quantifying semantic distance with semantic network path length.

PubMed

Kenett, Yoed N; Levi, Effi; Anaki, David; Faust, Miriam

2017-09-01

Semantic distance is a determining factor in cognitive processes, such as semantic priming, operating upon semantic memory. The main computational approach to compute semantic distance is through latent semantic analysis (LSA). However, objections have been raised against this approach, mainly in its failure at predicting semantic priming. We propose a novel approach to computing semantic distance, based on network science methodology. Path length in a semantic network represents the amount of steps needed to traverse from 1 word in the network to the other. We examine whether path length can be used as a measure of semantic distance, by investigating how path length affect performance in a semantic relatedness judgment task and recall from memory. Our results show a differential effect on performance: Up to 4 steps separating between word-pairs, participants exhibit an increase in reaction time (RT) and decrease in the percentage of word-pairs judged as related. From 4 steps onward, participants exhibit a significant decrease in RT and the word-pairs are dominantly judged as unrelated. Furthermore, we show that as path length between word-pairs increases, success in free- and cued-recall decreases. Finally, we demonstrate how our measure outperforms computational methods measuring semantic distance (LSA and positive pointwise mutual information) in predicting participants RT and subjective judgments of semantic strength. Thus, we provide a computational alternative to computing semantic distance. Furthermore, this approach addresses key issues in cognitive theory, namely the breadth of the spreading activation process and the effect of semantic distance on memory retrieval. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Mechanisms of masked evaluative priming: task sets modulate behavioral and electrophysiological priming for picture and words differentially

PubMed Central

Liegel, Nathalie; Zovko, Monika; Wentura, Dirk

2017-01-01

Abstract Research with the evaluative priming paradigm has shown that affective evaluation processes reliably influence cognition and behavior, even when triggered outside awareness. However, the precise mechanisms underlying such subliminal evaluative priming effects, response activation vs semantic processing, are matter of a debate. In this study, we determined the relative contribution of semantic processing and response activation to masked evaluative priming with pictures and words. To this end, we investigated the modulation of masked pictorial vs verbal priming by previously activated perceptual vs semantic task sets and assessed the electrophysiological correlates of priming using event-related potential (ERP) recordings. Behavioral and electrophysiological effects showed a differential modulation of pictorial and verbal subliminal priming by previously activated task sets: Pictorial priming was only observed during the perceptual but not during the semantic task set. Verbal priming, in contrast, was found when either task set was activated. Furthermore, only verbal priming was associated with a modulation of the N400 ERP component, an index of semantic processing, whereas a priming-related modulation of earlier ERPs, indexing visuo-motor S-R activation, was found for both picture and words. The results thus demonstrate that different neuro-cognitive processes contribute to unconscious evaluative priming depending on the stimulus format. PMID:27998994

Differential Prefrontal and Frontotemporal Oxygenation Patterns during Phonemic and Semantic Verbal Fluency

ERIC Educational Resources Information Center

Tupak, Sara V.; Badewien, Meike; Dresler, Thomas; Hahn, Tim; Ernst, Lena H.; Herrmann, Martin J.; Fallgatter, Andreas J.; Ehlis, Ann-Christine

2012-01-01

Movement artifacts are still considered a problematic issue for imaging research on overt language production. This motion-sensitivity can be overcome by functional near-infrared spectroscopy (fNIRS). In the present study, 50 healthy subjects performed a combined phonemic and semantic overt verbal fluency task while frontal and temporal cortex…

Dynamic switching between semantic and episodic memory systems.

PubMed

Kompus, Kristiina; Olsson, Carl-Johan; Larsson, Anne; Nyberg, Lars

2009-09-01

It has been suggested that episodic and semantic long-term memory systems interact during retrieval. Here we examined the flexibility of memory retrieval in an associative task taxing memories of different strength, assumed to differentially engage episodic and semantic memory. Healthy volunteers were pre-trained on a set of 36 face-name pairs over a 6-week period. Another set of 36 items was shown only once during the same time period. About 3 months after the training period all items were presented in a randomly intermixed order in an event-related fMRI study of face-name memory. Once presented items differentially activated anterior cingulate cortex and a right prefrontal region that previously have been associated with episodic retrieval mode. High-familiar items were associated with stronger activation of posterior cortices and a left frontal region. These findings fit a model of memory retrieval by which early processes determine, on a trial-by-trial basis, if the task can be solved by the default semantic system. If not, there is a dynamic shift to cognitive control processes that guide retrieval from episodic memory.

Form and meaning in early morphological processing: Comment on Feldman, O'Connor, and Moscoso del Prado Martin (2009).

PubMed

Davis, Matthew H; Rastle, Kathleen

2010-10-01

Feldman, O'Connor, and Moscoso del Prado Martín (2009) reported evidence for differential priming of semantically transparent (talker-talk) and semantically opaque (corner-corn) morphological pairs under masked presentation conditions. The present commentary argues that these data should not call into question the theory that morphologically structured words undergo a segmentation process based solely on form, because (1) these results do not contradict existing evidence for morpho-orthographic segmentation, (2) funnel plots suggest that the lack of priming observed for semantically opaque items in this study is inconsistent with findings in the existing literature, and (3) orthographic characteristics of the semantically opaque pairs in this study (rather than semantic factors) are the most likely explanation for these discrepant results.

An investigation into semantic and phonological processing in individuals with Williams syndrome.

PubMed

Lee, Cheryl S; Binder, Katherine S

2014-02-01

The current study examined semantic and phonological processing in individuals with Williams syndrome (WS). Previous research in language processing in individuals with WS suggests a complex linguistic system characterized by "deviant" semantic organization and differential phonological processing. Two experiments explored these representations in individuals with WS. The first experiment analyzed the relative typicality and frequency of participants' responses to a semantic and phonological fluency task. The second experiment tapped into online language processing through a semantic priming task and an online sentence reading task measuring the effects of word frequency. Thirteen participants with WS were matched to a group of participants on reading grade level and a group of participants on chronological age. The results of the semantic fluency task, semantic priming task, and word frequency task suggest that semantic organization in individuals with WS appears commensurate with their reading level rather than deviant. The pattern of results suggests that individuals with WS do not appear to have deviant semantic organization, while confirming that online tasks that tap into these processes are a promising direction in investigations that include atypically developing populations. These findings for the phonological tasks warrant further research into phonological processing in individuals with WS.

An Attribute-Treatment Interaction Study: Lexical-Set versus Semantically-Unrelated Vocabulary Instruction

ERIC Educational Resources Information Center

Hashemi, Mohammad Reza; Gowdasiaei, Farah

2005-01-01

The purpose of the current study was (a) to assess the effectiveness of the lexical-set (LS) and the semantically-unrelated (SU) vocabulary instruction, separately and relative to each other, and (b) to assess the differential effects of the two methods for students of lower and upper English proficiency levels. Two intact EFL classes were…

The Construct Validity of Higher Order Factors Emphasizing Symbolic and Semantic Content Abilities.

ERIC Educational Resources Information Center

Khattab, Ali-Maher

This study investigates the extent to which the higher order factors of symbolic and semantic content are differentiated. The main concern is an expository description of the use of confirmatory factor analysis in establishing factorial validity. Reanalyzed data originally collected in 1968 involved a sample of 197 tenth, eleventh and twelfth…

The Local Geometry of Multiattribute Tradeoff Preferences

PubMed Central

McGeachie, Michael; Doyle, Jon

2011-01-01

Existing representations for multiattribute ceteris paribus preference statements have provided useful treatments and clear semantics for qualitative comparisons, but have not provided similarly clear representations or semantics for comparisons involving quantitative tradeoffs. We use directional derivatives and other concepts from elementary differential geometry to interpret conditional multiattribute ceteris paribus preference comparisons that state bounds on quantitative tradeoff ratios. This semantics extends the familiar economic notion of marginal rate of substitution to multiple continuous or discrete attributes. The same geometric concepts also provide means for interpreting statements about the relative importance of different attributes. PMID:21528018

Acoustic and semantic interference effects in words and pictures.

PubMed

Dhawan, M; Pellegrino, J W

1977-05-01

Interference effects for pictures and words were investigated using a probe-recall task. Word stimuli showed acoustic interference effects for items at the end of the list and semantic interference effects for items at the beginning of the list, similar to results of Kintsch and Buschke (1969). Picture stimuli showed large semantic interference effects at all list positions with smaller acoustic interference effects. The results were related to latency data on picture-word processing and interpreted in terms of the differential order, probability, and/or speed of access to acoustic and semantic levels of processing. A levels of processing explanation of picture-word retention differences was related to dual coding theory. Both theoretical positions converge on an explanation of picture-word retention differences as a function of the relative capacity for semantic or associative processing.

Mechanisms of masked evaluative priming: task sets modulate behavioral and electrophysiological priming for picture and words differentially.

PubMed

Kiefer, Markus; Liegel, Nathalie; Zovko, Monika; Wentura, Dirk

2017-04-01

Research with the evaluative priming paradigm has shown that affective evaluation processes reliably influence cognition and behavior, even when triggered outside awareness. However, the precise mechanisms underlying such subliminal evaluative priming effects, response activation vs semantic processing, are matter of a debate. In this study, we determined the relative contribution of semantic processing and response activation to masked evaluative priming with pictures and words. To this end, we investigated the modulation of masked pictorial vs verbal priming by previously activated perceptual vs semantic task sets and assessed the electrophysiological correlates of priming using event-related potential (ERP) recordings. Behavioral and electrophysiological effects showed a differential modulation of pictorial and verbal subliminal priming by previously activated task sets: Pictorial priming was only observed during the perceptual but not during the semantic task set. Verbal priming, in contrast, was found when either task set was activated. Furthermore, only verbal priming was associated with a modulation of the N400 ERP component, an index of semantic processing, whereas a priming-related modulation of earlier ERPs, indexing visuo-motor S-R activation, was found for both picture and words. The results thus demonstrate that different neuro-cognitive processes contribute to unconscious evaluative priming depending on the stimulus format. © The Author (2016). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

When the Wedding March becomes sad: Semantic memory impairment for music in the semantic variant of primary progressive aphasia.

PubMed

Macoir, Joël; Berubé-Lalancette, Sarah; Wilson, Maximiliano A; Laforce, Robert; Hudon, Carol; Gravel, Pierre; Potvin, Olivier; Duchesne, Simon; Monetta, Laura

2016-12-01

Music can induce particular emotions and activate semantic knowledge. In the semantic variant of primary progressive aphasia (svPPA), semantic memory is impaired as a result of anterior temporal lobe (ATL) atrophy. Semantics is responsible for the encoding and retrieval of factual knowledge about music, including associative and emotional attributes. In the present study, we report the performance of two individuals with svPPA in three experiments. NG with bilateral ATL atrophy and ND with atrophy largely restricted to the left ATL. Experiment 1 assessed the recognition of musical excerpts and both patients were unimpaired. Experiment 2 studied the emotions conveyed by music and only NG showed impaired performance. Experiment 3 tested the association of semantic concepts to musical excerpts and both patients were impaired. These results suggest that the right ATL seems essential for the recognition of emotions conveyed by music and that the left ATL is involved in binding music to semantics. They are in line with the notion that the ATLs are devoted to the binding of different modality-specific properties and suggest that they are also differentially involved in the processing of factual and emotional knowledge associated with music.

Personal semantics: Is it distinct from episodic and semantic memory? An electrophysiological study of memory for autobiographical facts and repeated events in honor of Shlomo Bentin.

PubMed

Renoult, Louis; Tanguay, Annick; Beaudry, Myriam; Tavakoli, Paniz; Rabipour, Sheida; Campbell, Kenneth; Moscovitch, Morris; Levine, Brian; Davidson, Patrick S R

2016-03-01

Declarative memory is thought to consist of two independent systems: episodic and semantic. Episodic memory represents personal and contextually unique events, while semantic memory represents culturally-shared, acontextual factual knowledge. Personal semantics refers to aspects of declarative memory that appear to fall somewhere in between the extremes of episodic and semantic. Examples include autobiographical knowledge and memories of repeated personal events. These two aspects of personal semantics have been studied little and rarely compared to both semantic and episodic memory. We recorded the event-related potentials (ERPs) of 27 healthy participants while they verified the veracity of sentences probing four types of questions: general (i.e., semantic) facts, autobiographical facts, repeated events, and unique (i.e., episodic) events. Behavioral results showed equivalent reaction times in all 4 conditions. True sentences were verified faster than false sentences, except for unique events for which no significant difference was observed. Electrophysiological results showed that the N400 (which is classically associated with retrieval from semantic memory) was maximal for general facts and the LPC (which is classically associated with retrieval from episodic memory) was maximal for unique events. For both ERP components, the two personal semantic conditions (i.e., autobiographical facts and repeated events) systematically differed from semantic memory. In addition, N400 amplitudes also differentiated autobiographical facts from unique events. Autobiographical facts and repeated events did not differ significantly from each other but their corresponding scalp distributions differed from those associated with general facts. Our results suggest that the neural correlates of personal semantics can be distinguished from those of semantic and episodic memory, and may provide clues as to how unique events are transformed to semantic memory. Copyright © 2015 Elsevier Ltd. All rights reserved.

Distinct neural substrates for semantic knowledge and naming in the temporoparietal network.

PubMed

Gesierich, Benno; Jovicich, Jorge; Riello, Marianna; Adriani, Michela; Monti, Alessia; Brentari, Valentina; Robinson, Simon D; Wilson, Stephen M; Fairhall, Scott L; Gorno-Tempini, Maria Luisa

2012-10-01

Patients with anterior temporal lobe (ATL) lesions show semantic and lexical retrieval deficits, and the differential role of this area in the 2 processes is debated. Functional neuroimaging in healthy individuals has not clarified the matter because semantic and lexical processes usually occur simultaneously and automatically. Furthermore, the ATL is a region challenging for functional magnetic resonance imaging (fMRI) due to susceptibility artifacts, especially at high fields. In this study, we established an optimized ATL-sensitive fMRI acquisition protocol at 4 T and applied an event-related paradigm to study the identification (i.e., association of semantic biographical information) of celebrities, with and without the ability to retrieve their proper names. While semantic processing reliably activated the ATL, only more posterior areas in the left temporal and temporal-parietal junction were significantly modulated by covert lexical retrieval. These results suggest that within a temporoparietal network, the ATL is relatively more important for semantic processing, and posterior language regions are relatively more important for lexical retrieval.

Differential patterns of contextual organization of memory in first-episode psychosis.

PubMed

Murty, Vishnu P; McKinney, Rachel A; DuBrow, Sarah; Jalbrzikowski, Maria; Haas, Gretchen L; Luna, Beatriz

2018-02-15

Contextual information is used to support and organize episodic memory. Prior research has reliably shown memory deficits in psychosis; however, little research has characterized how this population uses contextual information during memory recall. We employed an approach founded in a computational framework of free recall to quantify how individuals with first episode of psychosis (FEP, N = 97) and controls (CON, N = 55) use temporal and semantic context to organize memory recall. Free recall was characterized using the Hopkins Verbal Learning Test-Revised (HVLT-R). We compared FEP and CON on three measures of free recall: proportion recalled, temporal clustering, and semantic clustering. Measures of temporal/semantic clustering quantified how individuals use contextual information to organize memory recall. We also assessed to what extent these measures relate to antipsychotic use and differentiated between different types of psychosis. We also explored the relationship between these measures and intelligence. In comparison to CON, FEP had reduced recall and less temporal clustering during free recall (p < 0.05, Bonferroni-corrected), and showed a trend towards greater semantic clustering (p = 0.10, Bonferroni-corrected). Within FEP, antipsychotic use and diagnoses did not differentiate between free recall accuracy or contextual organization of memory. IQ was related to free recall accuracy, but not the use of contextual information during recall in either group (p < 0.05, Bonferroni-corrected). These results show that in addition to deficits in memory recall, FEP differed in how they organize memories compared to CON.

A Developmental Study of Conceptual, Semantic Differential, and Acoustical Dimensions as Encoding Categories in Short-Term Memory. Final Report.

ERIC Educational Resources Information Center

Pender, Nola J.

The purpose of this research was to investigate developmental changes in encoding processes. It attempted to determine the extent to which children of varying ages utilize semantic (denotative or connotative) and acoustical encoding categories in a short-term memory task. It appears to be a reasonable assumption that as associational hierarchies…

Phonological fluency strategy of switching differentiates relapsing-remitting and secondary progressive multiple sclerosis patients.

PubMed

Messinis, L; Kosmidis, M H; Vlahou, C; Malegiannaki, A C; Gatzounis, G; Dimisianos, N; Karra, A; Kiosseoglou, G; Gourzis, P; Papathanasopoulos, P

2013-01-01

The strategies used to perform a verbal fluency task appear to be reflective of cognitive abilities necessary for successful daily functioning. In the present study, we explored potential differences in verbal fluency strategies (switching and clustering) used to maximize word production by patients with relapsing-remitting multiple sclerosis (RRMS) versus patients with secondary progressive multiple sclerosis (SPMS). We further assessed impairment rates and potential differences in the sensitivity and specificity of phonological versus semantic verbal fluency tasks in discriminating between those with a diagnosis of MS and healthy adults. We found that the overall rate of impaired verbal fluency in our MS sample was consistent with that in other studies. However, we found no differences between types of MS (SPMS, RRMS), on semantic or phonological fluency word production, or the strategies used to maximize semantic fluency. In contrast, we found that the number of switches differed significantly in the phonological fluency task between the SPMS and RRMS subtypes. The clinical utility of semantic versus phonological fluency in discriminating MS patients from healthy controls did not indicate any significant differences. Further, the strategies used to maximize performance did not differentiate MS subgroups or MS patients from healthy controls.

A Semantic Labeling of the Environment Based on What People Do.

PubMed

Crespo, Jonathan; Gómez, Clara; Hernández, Alejandra; Barber, Ramón

2017-01-29

In this work, a system is developed for semantic labeling of locations based on what people do. This system is useful for semantic navigation of mobile robots. The system differentiates environments according to what people do in them. Background sound, number of people in a room and amount of movement of those people are items to be considered when trying to tell if people are doing different actions. These data are sampled, and it is assumed that people behave differently and perform different actions. A support vector machine is trained with the obtained samples, and therefore, it allows one to identify the room. Finally, the results are discussed and support the hypothesis that the proposed system can help to semantically label a room.

Inducing and assessing differentiated emotion-feeling states in the laboratory.

PubMed

Philippot, P

1993-03-01

Two questions are addressed. The first question pertains to the capacity of film segments to induce emotional states that are: (a) as comparable as possible to naturally occurring emotions; (b) similar across individuals; and (c) clearly differentiated across the intended emotions. The second question concerns the discriminant capacity of self-report questionnaires of emotion-feeling states differing in their theoretical assumptions. Subjects viewed six short film segments and rated the strength of their responses on one of three kinds of questionnaires. The questionnaires were: (1) the Differential Emotions Scale that postulates category-based distinctions between emotions; (2) the Semantic Differential that postulates that emotions are distinguished along bipolar dimensions; and (3) free labelling of their feelings by the subjects (control condition with no theoretical a priori). Overall, results indicate that film segments can elicit a diversity of predictable emotions, in the same way, in a majority of individuals. In the present procedure, the Differential Emotions Scale yielded a better discrimination between emotional states than the Semantic Differential. Implications for emotion research and theories of the cognitive structure of emotion are discussed.

Differential interference effects of negative emotional states on subsequent semantic and perceptual processing

PubMed Central

Gorlick, Marissa A.; Mather, Mara

2012-01-01

Past studies have revealed that encountering negative events interferes with cognitive processing of subsequent stimuli. The present study investigated whether negative events affect semantic and perceptual processing differently. Presentation of negative pictures produced slower reaction times than neutral or positive pictures in tasks that require semantic processing, such as natural/man-made judgments about drawings of objects, commonness judgments about objects, and categorical judgments about pairs of words. In contrast, negative picture presentation did not slow down judgments in subsequent perceptual processing (e.g., color judgments about words, and size judgments about objects). The subjective arousal level of negative pictures did not modulate the interference effects on semantic/perceptual processing. These findings indicate that encountering negative emotional events interferes with semantic processing of subsequent stimuli more strongly than perceptual processing, and that not all types of subsequent cognitive processing are impaired by negative events. PMID:22142207

On the influence of affective states on intuitive coherence judgements.

PubMed

Balas, Robert; Sweklej, Joanna; Pochwatko, Grzegorz; Godlewska, Malgorzata

2012-01-01

Recent research has shown that coherence judgements of semantically related word triads are facilitated by a subtle positive response triggered by their increased fluency of processing. Such positive affective response serves as a cue indicating semantic coherence. However, we argue that the fluency of processing is not the only source of affective response that can influence intuitive judgements. The present study investigated differential influences of mood and affective valence of solution words on intuitive coherence judgements. We show that affective cues resulting from processing fluency can be strengthened or weakened by inducing positive or negative affective response through the activation of solutions to semantically coherent triads. Also, mood is shown to impact the breadth of activated associations therefore affecting not only judgements of semantic coherence but also solvability of word triads. We discuss the implications of our findings for how people might form intuitive judgements of semantic coherence.

Differential interference effects of negative emotional states on subsequent semantic and perceptual processing.

PubMed

Sakaki, Michiko; Gorlick, Marissa A; Mather, Mara

2011-12-01

Past studies have revealed that encountering negative events interferes with cognitive processing of subsequent stimuli. The present study investigates whether negative events affect semantic and perceptual processing differently. Presentation of negative pictures produced slower reaction times than neutral or positive pictures in tasks that require semantic processing, such as natural or man-made judgments about drawings of objects, commonness judgments about objects, and categorical judgments about pairs of words. In contrast, negative picture presentation did not slow down judgments in subsequent perceptual processing (e.g., color judgments about words, size judgments about objects). The subjective arousal level of negative pictures did not modulate the interference effects on semantic or perceptual processing. These findings indicate that encountering negative emotional events interferes with semantic processing of subsequent stimuli more strongly than perceptual processing, and that not all types of subsequent cognitive processing are impaired by negative events. (c) 2011 APA, all rights reserved.

Semantic Differential Scale Method Can Reveal Multi-Dimensional Aspects of Mind Perception.

PubMed

Takahashi, Hideyuki; Ban, Midori; Asada, Minoru

2016-01-01

As humans, we tend to perceive minds in both living and non-living entities, such as robots. From a questionnaire developed in a previous mind perception study, authors found that perceived minds could be located on two dimensions "experience" and "agency." This questionnaire allowed the assessment of how we perceive minds of various entities from a multi-dimensional point of view. In this questionnaire, subjects had to evaluate explicit mental capacities of target characters (e.g., capacity to feel hunger). However, we sometimes perceive minds in non-living entities, even though we cannot attribute these evidently biological capacities to the entity. In this study, we performed a large-scale web survey to assess mind perception by using the semantic differential scale method. We revealed that two mind dimensions "emotion" and "intelligence," respectively, corresponded to the two mind dimensions (experience and agency) proposed in a previous mind perception study. We did this without having to ask about specific mental capacities. We believe that the semantic differential scale is a useful method to assess the dimensions of mind perception especially for non-living entities that are hard to be attributed to biological capacities.

Semantic and episodic memory in children with temporal lobe epilepsy: do they relate to literacy skills?

PubMed

Lah, Suncica; Smith, Mary Lou

2014-01-01

Children with temporal lobe epilepsy are at risk for deficits in new learning (episodic memory) and literacy skills. Semantic memory deficits and double dissociations between episodic and semantic memory have recently been found in this patient population. In the current study we investigate whether impairments of these 2 distinct memory systems relate to literacy skills. 57 children with unilateral temporal lobe epilepsy completed tests of verbal memory (episodic and semantic) and literacy skills (reading and spelling accuracy, and reading comprehension). For the entire group, semantic memory explained over 30% of variance in each of the literacy domains. Episodic memory explained a significant, but rather small proportion (< 10%) of variance in reading and spelling accuracy, but not in reading comprehension. Moreover, when children with opposite patterns of specific memory impairments (intact semantic/impaired episodic, intact episodic/impaired semantic) were compared, significant reductions in literacy skills were evident only in children with semantic memory impairments, but not in children with episodic memory impairments relative to the norms and to children with temporal lobe epilepsy who had intact memory. Our study provides the first evidence for differential relations between episodic and semantic memory impairments and literacy skills in children with temporal lobe epilepsy. As such, it highlights the urgent need to consider semantic memory deficits in management of children with temporal lobe epilepsy and undertake further research into the nature of reading difficulties of children with semantic memory impairments.

Automatic Semantic Facilitation in Anterior Temporal Cortex Revealed through Multimodal Neuroimaging

PubMed Central

Gramfort, Alexandre; Hämäläinen, Matti S.; Kuperberg, Gina R.

2013-01-01

A core property of human semantic processing is the rapid, facilitatory influence of prior input on extracting the meaning of what comes next, even under conditions of minimal awareness. Previous work has shown a number of neurophysiological indices of this facilitation, but the mapping between time course and localization—critical for separating automatic semantic facilitation from other mechanisms—has thus far been unclear. In the current study, we used a multimodal imaging approach to isolate early, bottom-up effects of context on semantic memory, acquiring a combination of electroencephalography (EEG), magnetoencephalography (MEG), and functional magnetic resonance imaging (fMRI) measurements in the same individuals with a masked semantic priming paradigm. Across techniques, the results provide a strikingly convergent picture of early automatic semantic facilitation. Event-related potentials demonstrated early sensitivity to semantic association between 300 and 500 ms; MEG localized the differential neural response within this time window to the left anterior temporal cortex, and fMRI localized the effect more precisely to the left anterior superior temporal gyrus, a region previously implicated in semantic associative processing. However, fMRI diverged from early EEG/MEG measures in revealing semantic enhancement effects within frontal and parietal regions, perhaps reflecting downstream attempts to consciously access the semantic features of the masked prime. Together, these results provide strong evidence that automatic associative semantic facilitation is realized as reduced activity within the left anterior superior temporal cortex between 300 and 500 ms after a word is presented, and emphasize the importance of multimodal neuroimaging approaches in distinguishing the contributions of multiple regions to semantic processing. PMID:24155321

The differential contributions of pFC and temporo-parietal cortex to multimodal semantic control: exploring refractory effects in semantic aphasia.

PubMed

Gardner, Hannah E; Lambon Ralph, Matthew A; Dodds, Naomi; Jones, Theresa; Ehsan, Sheeba; Jefferies, Elizabeth

2012-04-01

Aphasic patients with multimodal semantic impairment following pFC or temporo-parietal (TP) cortex damage (semantic aphasia [SA]) have deficits characterized by poor control of semantic activation/retrieval, as opposed to loss of semantic knowledge per se. In line with this, SA patients show "refractory effects"; that is, declining accuracy in cyclical word-picture matching tasks when semantically related sets are presented rapidly and repeatedly. This is argued to follow a build-up of competition between targets and distractors. However, the link between poor semantic control and refractory effects is still controversial for two reasons. (1) Some theories propose that refractory effects are specific to verbal or auditory tasks, yet SA patients show poor control over semantic processing in both word and picture semantic tasks. (2) SA can result from lesions to either the left pFC or TP cortex, yet previous work suggests that refractory effects are specifically linked to the left inferior frontal cortex. For the first time, verbal, visual, and nonverbal auditory refractory effects were explored in nine SA patients who had pFC (pFC+) or TP cortex (TP-only) lesions. In all modalities, patient accuracy declined significantly over repetitions. This refractory effect at the group level was driven by pFC+ patients and was not shown by individuals with TP-only lesions. These findings support the theory that SA patients have reduced control over multimodal semantic retrieval and, additionally, suggest there may be functional specialization within the posterior versus pFC elements of the semantic control network.

Autobiographical memory for the differential diagnosis of cognitive pathology in aging.

PubMed

Meléndez, Juan C; Redondo, Rita; Torres, Marta; Mayordomo, Teresa; Sales, Alicia

2016-11-01

The present study distinguishes three memory stages across the lifespan, and aims to compare episodic and semantic autobiographical memory in healthy older adults, with amnesic mild cognitive impairment, and with Alzheimer's disease. This information can offer evidence about the way semantic and episodic autobiographical memory work, and how the disease affects them. The sample was composed of 56 people, all aged over 60 years; 15 with amnestic mild cognitive impairment, 12 with Alzheimer's disease and 29 healthy older people. Participants were evaluated with the Autobiographical Memory Interview. A mixed anova showed significant main effects of memory and time-period, and significant interactions of memory × group, time-period × group and memory × time × group. Assessment of autobiographical memory provides information to differentiate amnestic mild cognitive impairment patients from Alzheimer's disease patients. Although the decline in episodic memory starts with the onset of the disease, semantic memory is maintained until moderate stages of dementia. Geriatr Gerontol Int 2016; 16:1220-1225. © 2015 Japan Geriatrics Society.

Distinct loci of lexical and semantic access deficits in aphasia: Evidence from voxel-based lesion-symptom mapping and diffusion tensor imaging.

PubMed

Harvey, Denise Y; Schnur, Tatiana T

2015-06-01

Naming pictures and matching words to pictures belonging to the same semantic category negatively affects language production and comprehension. By most accounts, semantic interference arises when accessing lexical representations in naming (e.g., Damian, Vigliocco, & Levelt, 2001) and semantic representations in comprehension (e.g., Forde & Humphreys, 1997). Further, damage to the left inferior frontal gyrus (LIFG), a region implicated in cognitive control, results in increasing semantic interference when items repeat across cycles in both language production and comprehension (Jefferies, Baker, Doran, & Lambon Ralph, 2007). This generates the prediction that the LIFG via white matter connections supports resolution of semantic interference arising from different loci (lexical vs semantic) in the temporal lobe. However, it remains unclear whether the cognitive and neural mechanisms that resolve semantic interference are the same across tasks. Thus, we examined which gray matter structures [using whole brain and region of interest (ROI) approaches] and white matter connections (using deterministic tractography) when damaged impact semantic interference and its increase across cycles when repeatedly producing and understanding words in 15 speakers with varying lexical-semantic deficits from left hemisphere stroke. We found that damage to distinct brain regions, the posterior versus anterior temporal lobe, was associated with semantic interference (collapsed across cycles) in naming and comprehension, respectively. Further, those with LIFG damage compared to those without exhibited marginally larger increases in semantic interference across cycles in naming but not comprehension. Lastly, the inferior fronto-occipital fasciculus, connecting the LIFG with posterior temporal lobe, related to semantic interference in naming, whereas the inferior longitudinal fasciculus (ILF), connecting posterior with anterior temporal regions related to semantic interference in comprehension. These neuroanatomical-behavioral findings have implications for models of the lexical-semantic language network by demonstrating that semantic interference in language production and comprehension involves different representations which differentially recruit a cognitive control mechanism for interference resolution. Copyright © 2015 Elsevier Ltd. All rights reserved.

Differential Medial Temporal Lobe and Parietal Cortical Contributions to Real-world Autobiographical Episodic and Autobiographical Semantic Memory.

PubMed

Brown, Thackery I; Rissman, Jesse; Chow, Tiffany E; Uncapher, Melina R; Wagner, Anthony D

2018-04-18

Autobiographical remembering can depend on two forms of memory: episodic (event) memory and autobiographical semantic memory (remembering personally relevant semantic knowledge, independent of recalling a specific experience). There is debate about the degree to which the neural signals that support episodic recollection relate to or build upon autobiographical semantic remembering. Pooling data from two fMRI studies of memory for real-world personal events, we investigated whether medial temporal lobe (MTL) and parietal subregions contribute to autobiographical episodic and semantic remembering. During scanning, participants made memory judgments about photograph sequences depicting past events from their life or from others' lives, and indicated whether memory was based on episodic or semantic knowledge. Results revealed several distinct functional patterns: activity in most MTL subregions was selectively associated with autobiographical episodic memory; the hippocampal tail, superior parietal lobule, and intraparietal sulcus were similarly engaged when memory was based on retrieval of an autobiographical episode or autobiographical semantic knowledge; and angular gyrus demonstrated a graded pattern, with activity declining from autobiographical recollection to autobiographical semantic remembering to correct rejections of novel events. Collectively, our data offer insights into MTL and parietal cortex functional organization, and elucidate circuitry that supports different forms of real-world autobiographical memory.

How are 'Barack Obama' and 'President Elect' differentially stored in the brain? An ERP investigation on the processing of proper and common noun pairs.

PubMed

Proverbio, Alice Mado; Mariani, Serena; Zani, Alberto; Adorni, Roberta

2009-09-23

One of the most debated issues in the cognitive neuroscience of language is whether distinct semantic domains are differentially represented in the brain. Clinical studies described several anomic dissociations with no clear neuroanatomical correlate. Neuroimaging studies have shown that memory retrieval is more demanding for proper than common nouns in that the former are purely arbitrary referential expressions. In this study a semantic relatedness paradigm was devised to investigate neural processing of proper and common nouns. 780 words (arranged in pairs of Italian nouns/adjectives and the first/last names of well known persons) were presented. Half pairs were semantically related ("Woody Allen" or "social security"), while the others were not ("Sigmund Parodi" or "judicial cream"). All items were balanced for length, frequency, familiarity and semantic relatedness. Participants were to decide about the semantic relatedness of the two items in a pair. RTs and N400 data suggest that the task was more demanding for common nouns. The LORETA neural generators for the related-unrelated contrast (for proper names) included the left fusiform gyrus, right medial temporal gyrus, limbic and parahippocampal regions, inferior parietal and inferior frontal areas, which are thought to be involved in the conjoined processing a familiar face with the relevant episodic information. Person name was more emotional and sensory vivid than common noun semantic access. When memory retrieval is not required, proper name access (conspecifics knowledge) is not more demanding. The neural generators of N400 to unrelated items (unknown persons and things) did not differ as a function of lexical class, thus suggesting that proper and common nouns are not treated differently as belonging to different grammatical classes.

How Are ‘Barack Obama’ and ‘President Elect’ Differentially Stored in the Brain? An ERP Investigation on the Processing of Proper and Common Noun Pairs

PubMed Central

Proverbio, Alice Mado; Mariani, Serena; Zani, Alberto; Adorni, Roberta

2009-01-01

Background One of the most debated issues in the cognitive neuroscience of language is whether distinct semantic domains are differentially represented in the brain. Clinical studies described several anomic dissociations with no clear neuroanatomical correlate. Neuroimaging studies have shown that memory retrieval is more demanding for proper than common nouns in that the former are purely arbitrary referential expressions. In this study a semantic relatedness paradigm was devised to investigate neural processing of proper and common nouns. Methodology/Principal Findings 780 words (arranged in pairs of Italian nouns/adjectives and the first/last names of well known persons) were presented. Half pairs were semantically related (“Woody Allen” or “social security”), while the others were not (“Sigmund Parodi” or “judicial cream”). All items were balanced for length, frequency, familiarity and semantic relatedness. Participants were to decide about the semantic relatedness of the two items in a pair. RTs and N400 data suggest that the task was more demanding for common nouns. The LORETA neural generators for the related-unrelated contrast (for proper names) included the left fusiform gyrus, right medial temporal gyrus, limbic and parahippocampal regions, inferior parietal and inferior frontal areas, which are thought to be involved in the conjoined processing a familiar face with the relevant episodic information. Person name was more emotional and sensory vivid than common noun semantic access. Conclusions/Significance When memory retrieval is not required, proper name access (conspecifics knowledge) is not more demanding. The neural generators of N400 to unrelated items (unknown persons and things) did not differ as a function of lexical class, thus suggesting that proper and common nouns are not treated differently as belonging to different grammatical classes. PMID:19774070

Episodic, but not semantic, autobiographical memory is reduced in amnestic mild cognitive impairment.

PubMed

Murphy, Kelly J; Troyer, Angela K; Levine, Brian; Moscovitch, Morris

2008-11-01

Amnestic mild cognitive impairment (aMCI) is characterized by decline in anterograde memory as measured by the ability to learn and remember new information. We investigated whether retrograde memory for autobiographical information was affected by aMCI. Eighteen control (age 66-84 years) and 17 aMCI (age 66-84 years) participants described a personal event from each of the five periods across the lifespan. These events were transcribed and scored according to procedures that separate episodic (specific happenings) from semantic (general knowledge) elements of autobiographical memory. Although both groups generated protocols of similar length, the composition of autobiographical recall differentiated the groups. The aMCI group protocols were characterized by reduced episodic and increased semantic information relative to the control group. Both groups showed a similar pattern of recall across time periods, with no evidence that the aMCI group had more difficulty recalling recent, rather than remote, life events. These results indicate that episodic and semantic autobiographical memories are differentially affected by the early brain changes associated with aMCI. Reduced autobiographical episodic memories in aMCI may be the result of medial temporal lobe dysfunction, consistent with multiple trace theory, or alternatively, could be related to dysfunction of a wider related network of neocortical structures. In contrast, the preservation of autobiographical semantic memories in aMCI suggests neural systems, such as lateral temporal cortex, that support these memories, may remain relatively intact.

The semantic component of the evoked potential of differentiation.

PubMed

Izmailov, Chingis A; Korshunova, Svetlana G; Sokolov, Yevgeniy N

2008-05-01

This work analyzes data from recordings of (occipital and temporal) cortical evoked potentials (called evoked potentials of differentiation (EPD) occurring in humans in response to an abrupt substitution of stimuli. As stimuli we used three groups of words: the names of the ten basic colors taken from Newton's color circle; the names of seven basic emotions forming Shlossberg's circle of emotions; and seven nonsense words comprised of random combinations of letters. Within each group of word stimuli we constructed a matrix of the differences between the amplitudes of mid-latency components of EPD for each pair of words. This matrix was analyzed using the method of multidimensional scaling. As a result of this analysis we were able to distinguish the semantic and configurational components of EPD amplitude. The semantic component of EPD amplitude was evaluated by comparing structure of the data obtained to the circular structures of emotion and color names. The configurational component was evaluated on the basis of the attribute of word length (number of letters). It was demonstrated that the semantic component of the EPD can only be detected in the left occipital lead at an interpeak amplitude of P120-N180. The configurational component is reflected in the occipital and temporal leads to an identical extent, but only in the amplitude of a later (N180-P230) component of the EPD. The results obtained are discussed in terms of the coding of categorized, configurational, and semantic attributes of a visual stimulus.

Pedophiles' ratings of adult and child photographs using a semantic differential.

PubMed

Hambridge, J A

1994-03-01

Recent knowledge of the widespread extent of child sexual abuse and its consequences has led to an increasing interest in the understanding and treatment of perpetrators. This study examined a group of pedophiles in an English Special Hospital to determine possible characteristics that make children attractive and adults unattractive to them, using Repertory Grid technique and Semantic Differential. A small number of significant findings suggest that pedophiles may perceive some children and women in an unusual way. The large number of insignificant findings are discussed with reference to the sensitivity of the instrument; the pedophiles' desire to give socially acceptable answers; and subject characteristics of low IQ and "psychopathic disorder." Future directions for research are suggested.

Application of a methodology for categorizing and differentiating urban soundscapes using acoustical descriptors and semantic-differential attributes.

PubMed

Torija, Antonio J; Ruiz, Diego P; Ramos-Ridao, A F

2013-07-01

A subjective and physical categorization of an ambient sound is the first step to evaluate the soundscape and provides a basis for designing or adapting this ambient sound to match people's expectations. For this reason, the main goal of this work is to develop a categorization and differentiation analysis of soundscapes on the basis of acoustical and perceptual variables. A hierarchical cluster analysis, using 15 semantic-differential attributes and acoustical descriptors to include an equivalent sound-pressure level, maximum-minimum sound-pressure level, impulsiveness of the sound-pressure level, sound-pressure level time course, and spectral composition, was conducted to classify soundscapes into different typologies. This analysis identified 15 different soundscape typologies. Furthermore, based on a discriminant analysis the acoustical descriptors, the crest factor (impulsiveness of the sound-pressure level), and the sound level at 125 Hz were found to be the acoustical variables with the highest impact in the differentiation of the recognized types of soundscapes. Finally, to determine how the different soundscape typologies differed from each other, both subjectively and acoustically, a study was performed.

Dissociating the effects of semantic grouping and rehearsal strategies on event-related brain potentials.

PubMed

Schleepen, T M J; Markus, C R; Jonkman, L M

2014-12-01

The application of elaborative encoding strategies during learning, such as grouping items on similar semantic categories, increases the likelihood of later recall. Previous studies have suggested that stimuli that encourage semantic grouping strategies had modulating effects on specific ERP components. However, these studies did not differentiate between ERP activation patterns evoked by elaborative working memory strategies like semantic grouping and more simple strategies like rote rehearsal. Identification of neurocognitive correlates underlying successful use of elaborative strategies is important to understand better why certain populations, like children or elderly people, have problems applying such strategies. To compare ERP activation during the application of elaborative versus more simple strategies subjects had to encode either four semantically related or unrelated pictures by respectively applying a semantic category grouping or a simple rehearsal strategy. Another goal was to investigate if maintenance of semantically grouped vs. ungrouped pictures modulated ERP-slow waves differently. At the behavioral level there was only a semantic grouping benefit in terms of faster responding on correct rejections (i.e. when the memory probe stimulus was not part of the memory set). At the neural level, during encoding semantic grouping only had a modest specific modulatory effect on a fronto-central Late Positive Component (LPC), emerging around 650 ms. Other ERP components (i.e. P200, N400 and a second Late Positive Component) that had been earlier related to semantic grouping encoding processes now showed stronger modulation by rehearsal than by semantic grouping. During maintenance semantic grouping had specific modulatory effects on left and right frontal slow wave activity. These results stress the importance of careful control of strategy use when investigating the neural correlates of elaborative encoding. Copyright © 2014 Elsevier B.V. All rights reserved.

Semantic embodiment, disembodiment or misembodiment? In search of meaning in modules and neuron circuits.

PubMed

Pulvermüller, Friedemann

2013-10-01

"Embodied" proposals claim that the meaning of at least some words, concepts and constructions is grounded in knowledge about actions and objects. An alternative "disembodied" position locates semantics in a symbolic system functionally detached from sensorimotor modules. This latter view is not tenable theoretically and has been empirically falsified by neuroscience research. A minimally-embodied approach now claims that action-perception systems may "color", but not represent, meaning; however, such minimal embodiment (misembodiment?) still fails to explain why action and perception systems exert causal effects on the processing of symbols from specific semantic classes. Action perception theory (APT) offers neurobiological mechanisms for "embodied" referential, affective and action semantics along with "disembodied" mechanisms of semantic abstraction, generalization and symbol combination, which draw upon multimodal brain systems. In this sense, APT suggests integrative-neuromechanistic explanations of why both sensorimotor and multimodal areas of the human brain differentially contribute to specific facets of meaning and concepts. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.

Data-driven classification of patients with primary progressive aphasia.

PubMed

Hoffman, Paul; Sajjadi, Seyed Ahmad; Patterson, Karalyn; Nestor, Peter J

2017-11-01

Current diagnostic criteria classify primary progressive aphasia into three variants-semantic (sv), nonfluent (nfv) and logopenic (lv) PPA-though the adequacy of this scheme is debated. This study took a data-driven approach, applying k-means clustering to data from 43 PPA patients. The algorithm grouped patients based on similarities in language, semantic and non-linguistic cognitive scores. The optimum solution consisted of three groups. One group, almost exclusively those diagnosed as svPPA, displayed a selective semantic impairment. A second cluster, with impairments to speech production, repetition and syntactic processing, contained a majority of patients with nfvPPA but also some lvPPA patients. The final group exhibited more severe deficits to speech, repetition and syntax as well as semantic and other cognitive deficits. These results suggest that, amongst cases of non-semantic PPA, differentiation mainly reflects overall degree of language/cognitive impairment. The observed patterns were scarcely affected by inclusion/exclusion of non-linguistic cognitive scores. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Are all judgments created equal? An fMRI study of semantic and episodic metamemory predictions.

PubMed

Reggev, Niv; Zuckerman, Maya; Maril, Anat

2011-04-01

Metamemory refers to the ability of individuals to monitor and control their own memory performance. Although little theoretical consideration of the possible differences between the monitoring of episodic and of semantic knowledge has been published, results from patient and drug studies that used the "feeling of knowing" (FOK) paradigm show a selective impairment in the accuracy of episodic monitoring but not in its semantic counterpart. Similarly, neuroimaging studies provide indirect evidence for separate patterns of activation during episodic or semantic FOKs. However, the semantic-episodic distinction hypothesis has not been directly addressed. In the current event-related fMRI study, we used a within-subject, within-experiment comparison of the monitoring of semantic and episodic content. Whereas the common neural correlates of episodic and semantic FOKs observed in this study generally replicate the previous neuroimaging findings, several regions were found to be differentially associated with each task. Activity of the right inferior frontal gyrus was modulated by the semantic-episodic factor only during the negative predictions of retrieval, suggesting that negative predictions are based on partially distinct mechanisms during each task. A posterior midline network, known to be activated during episodic retrieval, was activated during episodic and not semantic monitoring, suggesting that episodic FOKs rely, to some extent, on common episodic retrieval processes. These findings suggest that theoretical accounts of the etiology and function of FOKs may benefit from incorporating the prediction directionality (positive/negative) and the memory domain (semantic/episodic) distinctions. Copyright © 2011 Elsevier Ltd. All rights reserved.

Explicit semantic tasks are necessary to study semantic priming effects with high rates of repetition.

PubMed

Renoult, Louis; Wang, Xiaoxiao; Mortimer, Jennifer; Debruille, J Bruno

2012-04-01

The purpose of the present study was to clarify in which experimental conditions the semantic processing of repeated words is preserved. We contrasted a short (250 ms) and a long (1000 ms) stimulus onset asynchrony (SOA) in two different experiments, using a relatively low proportion of related words (30%). One group of participants performed a lexical decision task (LDT) and a second group performed an explicit semantic matching task with the same words (except for pseudowords) and the same task parameters. In both tasks, word stimuli consisted solely of two prime and two target words repeated throughout the experiment. The effects of semantic priming on reaction time (RT) and the amplitude of the N400 ERP were absent for both the short and the long SOA in the LDT. In contrast, in the explicit semantic task, these effects were significant. In this task, the activity of N400 generators in the left superior temporal gyrus and the inferior parietal cortex significantly differentiated primed and unprimed trials but this effect did not interact with SOA. Our results indicate that task instruction is critical to preserve semantic processing with repeated presentations. Using explicit semantic designs, it may be possible to study associative or categorical relations between individual concepts. Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Memory for pictures and words as a function of level of processing: Depth or dual coding?

PubMed

D'Agostino, P R; O'Neill, B J; Paivio, A

1977-03-01

The experiment was designed to test differential predictions derived from dual-coding and depth-of-processing hypotheses. Subjects under incidental memory instructions free recalled a list of 36 test events, each presented twice. Within the list, an equal number of events were assigned to structural, phonemic, and semantic processing conditions. Separate groups of subjects were tested with a list of pictures, concrete words, or abstract words. Results indicated that retention of concrete words increased as a direct function of the processing-task variable (structural < phonemic

Recognition and identification of famous faces in patients with unilateral temporal lobe epilepsy.

PubMed

Seidenberg, Michael; Griffith, Randall; Sabsevitz, David; Moran, Maria; Haltiner, Alan; Bell, Brian; Swanson, Sara; Hammeke, Thomas; Hermann, Bruce

2002-01-01

We examined the performance of 21 patients with unilateral temporal lobe epilepsy (TLE) and hippocampal damage (10 lefts, and 11 rights) and 10 age-matched controls on the recognition and identification (name and occupation) of well-known faces. Famous face stimuli were selected from four time periods; 1970s, 1980s, 1990-1994, and 1995-1996. Differential patterns of performance were observed for the left and right TLE group across distinct face processing components. The left TLE group showed a selective impairment in naming famous faces while they performed similar to the controls in face recognition and semantic identification (i.e. occupation). In contrast, the right TLE group was impaired across all components of face memory; face recognition, semantic identification, and face naming. Face naming impairment in the left TLE group was characterized by a temporal gradient with better naming performance for famous faces from more distant time periods. Findings are discussed in terms of the role of the temporal lobe system for the acquisition, retention, and retrieval of face semantic networks, and the differential effects of lateralized temporal lobe lesions in this process.

Semantic word impressions expressed by hue.

PubMed

Shinomori, Keizo; Komatsu, Honami

2018-04-01

We investigated the possibility of whether impressions of semantic words showing complex concepts could be stably expressed by hues. Using a paired comparison method, we asked ten subjects to select from a pair of hues the one that more suitably matched a word impression. We employed nine Japanese semantic words and used twelve hues from vivid tones in the practical color coordinate system. As examples of the results, for the word "vigorous" the most frequently selected color was yellow and the least selected was blue to purple; for "tranquil" the most selected was yellow to green and the least selected was red. Principal component analysis of the selection data indicated that the cumulative contribution rate of the first two components was 94.6%, and in the two-dimensional space of the components, all hues were distributed as a hue-circle shape. In addition, comparison with additional data of color impressions measured by a semantic differential method suggested that most semantic word impressions can be stably expressed by hue, but the impression of some words, such as "magnificent" cannot. These results suggest that semantic word impression can be expressed reasonably well by color, and that hues are treated as impressions from the hue circle, not from color categories.

Categorizing words through semantic memory navigation

NASA Astrophysics Data System (ADS)

Borge-Holthoefer, J.; Arenas, A.

2010-03-01

Semantic memory is the cognitive system devoted to storage and retrieval of conceptual knowledge. Empirical data indicate that semantic memory is organized in a network structure. Everyday experience shows that word search and retrieval processes provide fluent and coherent speech, i.e. are efficient. This implies either that semantic memory encodes, besides thousands of words, different kind of links for different relationships (introducing greater complexity and storage costs), or that the structure evolves facilitating the differentiation between long-lasting semantic relations from incidental, phenomenological ones. Assuming the latter possibility, we explore a mechanism to disentangle the underlying semantic backbone which comprises conceptual structure (extraction of categorical relations between pairs of words), from the rest of information present in the structure. To this end, we first present and characterize an empirical data set modeled as a network, then we simulate a stochastic cognitive navigation on this topology. We schematize this latter process as uncorrelated random walks from node to node, which converge to a feature vectors network. By doing so we both introduce a novel mechanism for information retrieval, and point at the problem of category formation in close connection to linguistic and non-linguistic experience.

Neural correlates of successful semantic processing during propofol sedation.

PubMed

Adapa, Ram M; Davis, Matthew H; Stamatakis, Emmanuel A; Absalom, Anthony R; Menon, David K

2014-07-01

Sedation has a graded effect on brain responses to auditory stimuli: perceptual processing persists at sedation levels that attenuate more complex processing. We used fMRI in healthy volunteers sedated with propofol to assess changes in neural responses to spoken stimuli. Volunteers were scanned awake, sedated, and during recovery, while making perceptual or semantic decisions about nonspeech sounds or spoken words respectively. Sedation caused increased error rates and response times, and differentially affected responses to words in the left inferior frontal gyrus (LIFG) and the left inferior temporal gyrus (LITG). Activity in LIFG regions putatively associated with semantic processing, was significantly reduced by sedation despite sedated volunteers continuing to make accurate semantic decisions. Instead, LITG activity was preserved for words greater than nonspeech sounds and may therefore be associated with persistent semantic processing during the deepest levels of sedation. These results suggest functionally distinct contributions of frontal and temporal regions to semantic decision making. These results have implications for functional imaging studies of language, for understanding mechanisms of impaired speech comprehension in postoperative patients with residual levels of anesthetic, and may contribute to the development of frameworks against which EEG based monitors could be calibrated to detect awareness under anesthesia. Copyright © 2013 Wiley Periodicals, Inc.

Influence of aging on the neural correlates of autobiographical, episodic, and semantic memory retrieval.

PubMed

St-Laurent, Marie; Abdi, Hervé; Burianová, Hana; Grady, Cheryl L

2011-12-01

We used fMRI to assess the neural correlates of autobiographical, semantic, and episodic memory retrieval in healthy young and older adults. Participants were tested with an event-related paradigm in which retrieval demand was the only factor varying between trials. A spatio-temporal partial least square analysis was conducted to identify the main patterns of activity characterizing the groups across conditions. We identified brain regions activated by all three memory conditions relative to a control condition. This pattern was expressed equally in both age groups and replicated previous findings obtained in a separate group of younger adults. We also identified regions whose activity differentiated among the different memory conditions. These patterns of differentiation were expressed less strongly in the older adults than in the young adults, a finding that was further confirmed by a barycentric discriminant analysis. This analysis showed an age-related dedifferentiation in autobiographical and episodic memory tasks but not in the semantic memory task or the control condition. These findings suggest that the activation of a common memory retrieval network is maintained with age, whereas the specific aspects of brain activity that differ with memory content are more vulnerable and less selectively engaged in older adults. Our results provide a potential neural mechanism for the well-known age differences in episodic/autobiographical memory, and preserved semantic memory, observed when older adults are compared with younger adults.

Overlap in the functional neural systems involved in semantic and episodic memory retrieval.

PubMed

Rajah, M N; McIntosh, A R

2005-03-01

Neuroimaging and neuropsychological data suggest that episodic and semantic memory may be mediated by distinct neural systems. However, an alternative perspective is that episodic and semantic memory represent different modes of processing within a single declarative memory system. To examine whether the multiple or the unitary system view better represents the data we conducted a network analysis using multivariate partial least squares (PLS ) activation analysis followed by covariance structural equation modeling (SEM) of positron emission tomography data obtained while healthy adults performed episodic and semantic verbal retrieval tasks. It is argued that if performance of episodic and semantic retrieval tasks are mediated by different memory systems, then there should differences in both regional activations and interregional correlations related to each type of retrieval task, respectively. The PLS results identified brain regions that were differentially active during episodic retrieval versus semantic retrieval. Regions that showed maximal differences in regional activity between episodic retrieval tasks were used to construct separate functional models for episodic and semantic retrieval. Omnibus tests of these functional models failed to find a significant difference across tasks for both functional models. The pattern of path coefficients for the episodic retrieval model were not different across tasks, nor were the path coefficients for the semantic retrieval model. The SEM results suggest that the same memory network/system was engaged across tasks, given the similarities in path coefficients. Therefore, activation differences between episodic and semantic retrieval may ref lect variation along a continuum of processing during task performance within the context of a single memory system.

Combining Temporal and Spectral Information with Spatial Mapping to Identify Differences between Phonological and Semantic Networks: A Magnetoencephalographic Approach.

PubMed

McNab, Fiona; Hillebrand, Arjan; Swithenby, Stephen J; Rippon, Gina

2012-01-01

Early, lesion-based models of language processing suggested that semantic and phonological processes are associated with distinct temporal and parietal regions respectively, with frontal areas more indirectly involved. Contemporary spatial brain mapping techniques have not supported such clear-cut segregation, with strong evidence of activation in left temporal areas by both processes and disputed evidence of involvement of frontal areas in both processes. We suggest that combining spatial information with temporal and spectral data may allow a closer scrutiny of the differential involvement of closely overlapping cortical areas in language processing. Using beamforming techniques to analyze magnetoencephalography data, we localized the neuronal substrates underlying primed responses to nouns requiring either phonological or semantic processing, and examined the associated measures of time and frequency in those areas where activation was common to both tasks. Power changes in the beta (14-30 Hz) and gamma (30-50 Hz) frequency bands were analyzed in pre-selected time windows of 350-550 and 500-700 ms In left temporal regions, both tasks elicited power changes in the same time window (350-550 ms), but with different spectral characteristics, low beta (14-20 Hz) for the phonological task and high beta (20-30 Hz) for the semantic task. In frontal areas (BA10), both tasks elicited power changes in the gamma band (30-50 Hz), but in different time windows, 500-700 ms for the phonological task and 350-550 ms for the semantic task. In the left inferior parietal area (BA40), both tasks elicited changes in the 20-30 Hz beta frequency band but in different time windows, 350-550 ms for the phonological task and 500-700 ms for the semantic task. Our findings suggest that, where spatial measures may indicate overlapping areas of involvement, additional beamforming techniques can demonstrate differential activation in time and frequency domains.

Autobiographically significant concepts: more episodic than semantic in nature? An electrophysiological investigation of overlapping types of memory.

PubMed

Renoult, Louis; Davidson, Patrick S R; Schmitz, Erika; Park, Lillian; Campbell, Kenneth; Moscovitch, Morris; Levine, Brian

2015-01-01

A common assertion is that semantic memory emerges from episodic memory, shedding the distinctive contexts associated with episodes over time and/or repeated instances. Some semantic concepts, however, may retain their episodic origins or acquire episodic information during life experiences. The current study examined this hypothesis by investigating the ERP correlates of autobiographically significant (AS) concepts, that is, semantic concepts that are associated with vivid episodic memories. We inferred the contribution of semantic and episodic memory to AS concepts using the amplitudes of the N400 and late positive component, respectively. We compared famous names that easily brought to mind episodic memories (high AS names) against equally famous names that did not bring such recollections to mind (low AS names) on a semantic task (fame judgment) and an episodic task (recognition memory). Compared with low AS names, high AS names were associated with increased amplitude of the late positive component in both tasks. Moreover, in the recognition task, this effect of AS was highly correlated with recognition confidence. In contrast, the N400 component did not differentiate the high versus low AS names but, instead, was related to the amount of general knowledge participants had regarding each name. These results suggest that semantic concepts high in AS, such as famous names, have an episodic component and are associated with similar brain processes to those that are engaged by episodic memory. Studying AS concepts may provide unique insights into how episodic and semantic memory interact.

[Evaluation of temporality semantic knowledge in normal aging and in mild and moderate stages of Alzheimer's disease].

PubMed

Rivasseau Jonveaux, T; Batt, M; Empereur, F; Braun, M; Trognon, A

2015-04-01

Episodic and semantic processes are involved in temporality used in daily life. Episodic memory permits one to place an event on the time axis, while semantic memory makes us aware of the time segmentation and its symbolic representation. Memory of the knowledge connected to the passing of time is materialized on the calendar and can be seen symbolically on the dial of a clock. In AD, semantic memory processes are preserved longer than processes related to episodic memory. We wonder whether the specific field of knowledge about time is altered during AD. We validated a specific evaluation with a control group (354 healthy subjects). Then we applied this battery to assess AD patients to appreciate the feasibility of this tool for this population. We then compared 22 AD patients with a control group matched for age, sex and educational level. Our clinical scale of temporal semantic knowledge consists of four parts: (a) hour reading with a.m. and p.m. hours; (b) using a clock: 12 clock faces with the hour numbers already placed: the patient draws hour and minute hands for various hours; (c) temporal segmentation: exploration of the knowledge on daytime scale and of the calendar; (d) time duration estimation: calculate how long the interview has lasted after indicating the time of its beginning and its end, then the time between 10.40 to 12.00. While age and educational level had an influence on all the scores, in the two groups control and patients, gender did not. Temporal segmentation, independent of the cultural level, revealed the best acquired knowledge in our control population. All the scores differentiated patients from control subjects. The temporal semantic knowledge correlated with the AD severity seemed to be correlated with the attention, verbal comprehension, and some components of executive functions, but was not related to the clock drawing test result. Depression did not have any influence on this scale in our AD group. The temporal semantic knowledge clinical scale shows differential alterations, notably in hour reading and using a clock, and less in temporal segmentation. Temporal semantic knowledge is altered in AD. The diagnosis and follow-up of these alterations allow professionals and caregivers to consider adaptations of the patient's environment according to their needs. Copyright © 2013 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

Electrophysiological evidence for effects of color knowledge in object recognition.

PubMed

Lu, Aitao; Xu, Guiping; Jin, Hua; Mo, Lei; Zhang, Jijia; Zhang, John X

2010-01-29

Knowledge about the typical colors associated with familiar everyday objects (i.e., strawberries are red) is well-known to be represented in the conceptual semantic system. Evidence that such knowledge may also play a role in early perceptual processes for object recognition is scant. In the present ERP study, participants viewed a list of object pictures and detected infrequent stimulus repetitions. Results show that shortly after stimulus onset, ERP components indexing early perceptual processes, including N1, P2, and N2, differentiated between objects in their appropriate or congruent color from these objects in an inappropriate or incongruent color. Such congruence effect also occurred in N3 associated with semantic processing of pictures but not in N4 for domain-general semantic processing. Our results demonstrate a clear effect of color knowledge in early object recognition stages and support the following proposal-color as a surface property is stored in a multiple-memory system where pre-semantic perceptual and semantic conceptual representations interact during object recognition. (c) 2009 Elsevier Ireland Ltd. All rights reserved.

Neural dynamics associated with semantic and episodic memory for faces: evidence from multiple frequency bands.

PubMed

Zion-Golumbic, Elana; Kutas, Marta; Bentin, Shlomo

2010-02-01

Prior semantic knowledge facilitates episodic recognition memory for faces. To examine the neural manifestation of the interplay between semantic and episodic memory, we investigated neuroelectric dynamics during the creation (study) and the retrieval (test) of episodic memories for famous and nonfamous faces. Episodic memory effects were evident in several EEG frequency bands: theta (4-8 Hz), alpha (9-13 Hz), and gamma (40-100 Hz). Activity in these bands was differentially modulated by preexisting semantic knowledge and by episodic memory, implicating their different functional roles in memory. More specifically, theta activity and alpha suppression were larger for old compared to new faces at test regardless of fame, but were both larger for famous faces during study. This pattern of selective semantic effects suggests that the theta and alpha responses, which are primarily associated with episodic memory, reflect utilization of semantic information only when it is beneficial for task performance. In contrast, gamma activity decreased between the first (study) and second (test) presentation of a face, but overall was larger for famous than nonfamous faces. Hence, the gamma rhythm seems to be primarily related to activation of preexisting neural representations that may contribute to the formation of new episodic traces. Taken together, these data provide new insights into the complex interaction between semantic and episodic memory for faces and the neural dynamics associated with mnemonic processes.

Neuroanatomic substrates of semantic memory impairment in Alzheimer’s disease: Patterns of functional MRI activation

PubMed Central

SAYKIN, ANDREW J.; FLASHMAN, LAURA A.; FRUTIGER, SALLY A.; JOHNSON, STERLING C.; MAMOURIAN, ALEXANDER C.; MORITZ, CHAD H.; O’JILE, JUDITH R.; RIORDAN, HENRY J.; SANTULLI, ROBERT B.; SMITH, CYNTHIA A.; WEAVER, JOHN B.

2015-01-01

Impairment in semantic processing occurs early in Alzheimer’s disease (AD) and differential impact on subtypes of semantic relations have been reported, yet there is little data on the neuroanatomic basis of these deficits. Patients with mild AD and healthy controls underwent 3 functional MRI auditory stimulation tasks requiring semantic or phonological decisions (match–mismatch) about word pairs (category–exemplar, category–function, pseudoword). Patients showed a significant performance deficit only on the exemplar task. On voxel-based fMRI activation analyses, controls showed a clear activation focus in the left superior temporal gyrus for the phonological task; patients showed additional foci in the left dorsolateral prefrontal and bilateral cingulate areas. On the semantic tasks, predominant activation foci were seen in the inferior and middle frontal gyrus (left greater than right) in both groups but patients showed additional activation suggesting compensatory recruitment of locally expanded foci and remote regions, for example, right frontal activation during the exemplar task. Covariance analyses indicated that exemplar task performance was strongly related to signal increase in bilateral medial prefrontal cortex. The authors conclude that fMRI can reveal similarities and differences in functional neuroanatomical processing of semantic and phonological information in mild AD compared to healthy elderly, and can help to bridge cognitive and neural investigations of the integrity of semantic networks in AD. PMID:10439584

The Abilities and Differential Difficulties of Children with Autism Spectrum Disorder and Children with Specific Language Impairment to Use Semantic and Social Contexts to Infer and Recall Novel Words

ERIC Educational Resources Information Center

Goldman, Melody R.

2010-01-01

Two studies assessed the ability of 12 pre-school children with Autism Spectrum Disorder (ASD; N = 7) or Specific Language Impairment (SLI; N = 5) to use semantic context and eye gaze to infer the meanings of novel nouns, and to recall those meanings after a 24-hour delay. In Experiment 1, the children heard statements containing a familiar,…

(Pea)nuts and bolts of visual narrative: Structure and meaning in sequential image comprehension

PubMed Central

Cohn, Neil; Paczynski, Martin; Jackendoff, Ray; Holcomb, Phillip J.; Kuperberg, Gina R.

2012-01-01

Just as syntax differentiates coherent sentences from scrambled word strings, the comprehension of sequential images must also use a cognitive system to distinguish coherent narrative sequences from random strings of images. We conducted experiments analogous to two classic studies of language processing to examine the contributions of narrative structure and semantic relatedness to processing sequential images. We compared four types of comic strips: 1) Normal sequences with both structure and meaning, 2) Semantic Only sequences (in which the panels were related to a common semantic theme, but had no narrative structure), 3) Structural Only sequences (narrative structure but no semantic relatedness), and 4) Scrambled sequences of randomly-ordered panels. In Experiment 1, participants monitored for target panels in sequences presented panel-by-panel. Reaction times were slowest to panels in Scrambled sequences, intermediate in both Structural Only and Semantic Only sequences, and fastest in Normal sequences. This suggests that both semantic relatedness and narrative structure offer advantages to processing. Experiment 2 measured ERPs to all panels across the whole sequence. The N300/N400 was largest to panels in both the Scrambled and Structural Only sequences, intermediate in Semantic Only sequences and smallest in the Normal sequences. This implies that a combination of narrative structure and semantic relatedness can facilitate semantic processing of upcoming panels (as reflected by the N300/N400). Also, panels in the Scrambled sequences evoked a larger left-lateralized anterior negativity than panels in the Structural Only sequences. This localized effect was distinct from the N300/N400, and appeared despite the fact that these two sequence types were matched on local semantic relatedness between individual panels. These findings suggest that sequential image comprehension uses a narrative structure that may be independent of semantic relatedness. Altogether, we argue that the comprehension of visual narrative is guided by an interaction between structure and meaning. PMID:22387723

Semantic word category processing in semantic dementia and posterior cortical atrophy.

PubMed

Shebani, Zubaida; Patterson, Karalyn; Nestor, Peter J; Diaz-de-Grenu, Lara Z; Dawson, Kate; Pulvermüller, Friedemann

2017-08-01

There is general agreement that perisylvian language cortex plays a major role in lexical and semantic processing; but the contribution of additional, more widespread, brain areas in the processing of different semantic word categories remains controversial. We investigated word processing in two groups of patients whose neurodegenerative diseases preferentially affect specific parts of the brain, to determine whether their performance would vary as a function of semantic categories proposed to recruit those brain regions. Cohorts with (i) Semantic Dementia (SD), who have anterior temporal-lobe atrophy, and (ii) Posterior Cortical Atrophy (PCA), who have predominantly parieto-occipital atrophy, performed a lexical decision test on words from five different lexico-semantic categories: colour (e.g., yellow), form (oval), number (seven), spatial prepositions (under) and function words (also). Sets of pseudo-word foils matched the target words in length and bi-/tri-gram frequency. Word-frequency was matched between the two visual word categories (colour and form) and across the three other categories (number, prepositions, and function words). Age-matched healthy individuals served as controls. Although broad word processing deficits were apparent in both patient groups, the deficit was strongest for colour words in SD and for spatial prepositions in PCA. The patterns of performance on the lexical decision task demonstrate (a) general lexicosemantic processing deficits in both groups, though more prominent in SD than in PCA, and (b) differential involvement of anterior-temporal and posterior-parietal cortex in the processing of specific semantic categories of words. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Asymptotically Optimal and Private Statistical Estimation

NASA Astrophysics Data System (ADS)

Smith, Adam

Differential privacy is a definition of "privacy" for statistical databases. The definition is simple, yet it implies strong semantics even in the presence of an adversary with arbitrary auxiliary information about the database.

Aesthetic perception of visual textures: a holistic exploration using texture analysis, psychological experiment, and perception modeling.

PubMed

Liu, Jianli; Lughofer, Edwin; Zeng, Xianyi

2015-01-01

Modeling human aesthetic perception of visual textures is important and valuable in numerous industrial domains, such as product design, architectural design, and decoration. Based on results from a semantic differential rating experiment, we modeled the relationship between low-level basic texture features and aesthetic properties involved in human aesthetic texture perception. First, we compute basic texture features from textural images using four classical methods. These features are neutral, objective, and independent of the socio-cultural context of the visual textures. Then, we conduct a semantic differential rating experiment to collect from evaluators their aesthetic perceptions of selected textural stimuli. In semantic differential rating experiment, eights pairs of aesthetic properties are chosen, which are strongly related to the socio-cultural context of the selected textures and to human emotions. They are easily understood and connected to everyday life. We propose a hierarchical feed-forward layer model of aesthetic texture perception and assign 8 pairs of aesthetic properties to different layers. Finally, we describe the generation of multiple linear and non-linear regression models for aesthetic prediction by taking dimensionality-reduced texture features and aesthetic properties of visual textures as dependent and independent variables, respectively. Our experimental results indicate that the relationships between each layer and its neighbors in the hierarchical feed-forward layer model of aesthetic texture perception can be fitted well by linear functions, and the models thus generated can successfully bridge the gap between computational texture features and aesthetic texture properties.

User Evaluation of Neonatology Ward Design.

PubMed

Trujillo, Juan Luis Higuera; Aviñó, Antoni Montañana I; Millán, Carmen Llinares

2017-01-01

The object of this article is to identify the set of affective and emotional factors behind users' assessments of a space in a neonatology unit and to propose design guidelines based on these. The importance of the neonatology service and the variety of users place great demands on the space at all levels. Despite the repercussions, the emotional aspects of the environment have received less attention. To avoid incurring limitations in the user mental scheme, this study uses two complementary methodologies: focus group and semantic differential. The (qualitative) focus group methodology provides exploratory information and concepts. The (quantitative) semantic differential methodology then uses these concepts to extract the conceptual structures that users employ in their assessment of the space. Of the total 175 subjects, 31 took part in focus groups and 144 in semantic differential. Five independent concepts were identified: privacy, functionality and professional nature, spaciousness, lighting, and cleanliness. In relation to the importance of the overall positive assessment of the space, the perception of privacy and sensations of dominance and pleasure are fundamental. Six relevant design aspects were also identified: provide spacious surroundings, facilitate sufficient separation between the different posts or cots, use different colors from those usually found in health-care centers, as some aversion was found to white and especially green, design areas with childhood themes, use warm artificial light, and choose user-friendly equipment. Results provide design recommendations of interest and show the possibilities offered by combining both systems to analyze user response.

Neural Substrates of Semantic Prospection – Evidence from the Dementias

PubMed Central

Irish, Muireann; Eyre, Nadine; Dermody, Nadene; O’Callaghan, Claire; Hodges, John R.; Hornberger, Michael; Piguet, Olivier

2016-01-01

The ability to envisage personally relevant events at a future time point represents an incredibly sophisticated cognitive endeavor and one that appears to be intimately linked to episodic memory integrity. Far less is known regarding the neurocognitive mechanisms underpinning the capacity to envisage non-personal future occurrences, known as semantic future thinking. Moreover the degree of overlap between the neural substrates supporting episodic and semantic forms of prospection remains unclear. To this end, we sought to investigate the capacity for episodic and semantic future thinking in Alzheimer’s disease (n = 15) and disease-matched behavioral-variant frontotemporal dementia (n = 15), neurodegenerative disorders characterized by significant medial temporal lobe (MTL) and frontal pathology. Participants completed an assessment of past and future thinking across personal (episodic) and non-personal (semantic) domains, as part of a larger neuropsychological battery investigating episodic and semantic processing, and their performance was contrasted with 20 age- and education-matched healthy older Controls. Participants underwent whole-brain T1-weighted structural imaging and voxel-based morphometry analysis was conducted to determine the relationship between gray matter integrity and episodic and semantic future thinking. Relative to Controls, both patient groups displayed marked future thinking impairments, extending across episodic and semantic domains. Analyses of covariance revealed that while episodic future thinking deficits could be explained solely in terms of episodic memory proficiency, semantic prospection deficits reflected the interplay between episodic and semantic processing. Distinct neural correlates emerged for each form of future simulation with differential involvement of prefrontal, lateral temporal, and medial temporal regions. Notably, the hippocampus was implicated irrespective of future thinking domain, with the suggestion of lateralization effects depending on the type of information being simulated. Whereas episodic future thinking related to right hippocampal integrity, semantic future thinking was found to relate to left hippocampal integrity. Our findings support previous observations of significant MTL involvement for semantic forms of prospection and point to distinct neurocognitive mechanisms which must be functional to support future-oriented forms of thought across personal and non-personal contexts. PMID:27252632

One declarative memory system or two? The relationship between episodic and semantic memory in children with temporal lobe epilepsy.

PubMed

Smith, Mary Lou; Lah, Suncica

2011-09-01

This study explored verbal semantic and episodic memory in children with unilateral temporal lobe epilepsy to determine whether they had impairments in both or only 1 aspect of memory, and to examine relations between performance in the 2 domains. Sixty-six children and adolescents (37 with seizures of left temporal lobe onset, 29 with right-sided onset) were given 4 tasks assessing different aspects of semantic memory (picture naming, fluency, knowledge of facts, knowledge of word meanings) and 2 episodic memory tasks (story recall, word list recall). High rates of impairments were observed across tasks, and no differences were found related to the laterality of the seizures. Individual patient analyses showed that there was a double dissociation between the 2 aspects of memory in that some children were impaired on episodic but not semantic memory, whereas others showed intact episodic but impaired semantic memory. This double dissociation suggests that these 2 memory systems may develop independently in the context of temporal lobe pathology, perhaps related to differential effects of dysfunction in the lateral and mesial temporal lobe structures. PsycINFO Database Record (c) 2011 APA, all rights reserved.

Building a biomedical semantic network in Wikipedia with Semantic Wiki Links

PubMed Central

Good, Benjamin M.; Clarke, Erik L.; Loguercio, Salvatore; Su, Andrew I.

2012-01-01

Wikipedia is increasingly used as a platform for collaborative data curation, but its current technical implementation has significant limitations that hinder its use in biocuration applications. Specifically, while editors can easily link between two articles in Wikipedia to indicate a relationship, there is no way to indicate the nature of that relationship in a way that is computationally accessible to the system or to external developers. For example, in addition to noting a relationship between a gene and a disease, it would be useful to differentiate the cases where genetic mutation or altered expression causes the disease. Here, we introduce a straightforward method that allows Wikipedia editors to embed computable semantic relations directly in the context of current Wikipedia articles. In addition, we demonstrate two novel applications enabled by the presence of these new relationships. The first is a dynamically generated information box that can be rendered on all semantically enhanced Wikipedia articles. The second is a prototype gene annotation system that draws its content from the gene-centric articles on Wikipedia and exposes the new semantic relationships to enable previously impossible, user-defined queries. Database URL: http://en.wikipedia.org/wiki/Portal:Gene_Wiki PMID:22434829

Building a biomedical semantic network in Wikipedia with Semantic Wiki Links.

PubMed

Good, Benjamin M; Clarke, Erik L; Loguercio, Salvatore; Su, Andrew I

2012-01-01

Wikipedia is increasingly used as a platform for collaborative data curation, but its current technical implementation has significant limitations that hinder its use in biocuration applications. Specifically, while editors can easily link between two articles in Wikipedia to indicate a relationship, there is no way to indicate the nature of that relationship in a way that is computationally accessible to the system or to external developers. For example, in addition to noting a relationship between a gene and a disease, it would be useful to differentiate the cases where genetic mutation or altered expression causes the disease. Here, we introduce a straightforward method that allows Wikipedia editors to embed computable semantic relations directly in the context of current Wikipedia articles. In addition, we demonstrate two novel applications enabled by the presence of these new relationships. The first is a dynamically generated information box that can be rendered on all semantically enhanced Wikipedia articles. The second is a prototype gene annotation system that draws its content from the gene-centric articles on Wikipedia and exposes the new semantic relationships to enable previously impossible, user-defined queries. DATABASE URL: http://en.wikipedia.org/wiki/Portal:Gene_Wiki.

Brain connections of words, perceptions and actions: A neurobiological model of spatio-temporal semantic activation in the human cortex.

PubMed

Tomasello, Rosario; Garagnani, Max; Wennekers, Thomas; Pulvermüller, Friedemann

2017-04-01

Neuroimaging and patient studies show that different areas of cortex respectively specialize for general and selective, or category-specific, semantic processing. Why are there both semantic hubs and category-specificity, and how come that they emerge in different cortical regions? Can the activation time-course of these areas be predicted and explained by brain-like network models? In this present work, we extend a neurocomputational model of human cortical function to simulate the time-course of cortical processes of understanding meaningful concrete words. The model implements frontal and temporal cortical areas for language, perception, and action along with their connectivity. It uses Hebbian learning to semantically ground words in aspects of their referential object- and action-related meaning. Compared with earlier proposals, the present model incorporates additional neuroanatomical links supported by connectivity studies and downscaled synaptic weights in order to control for functional between-area differences purely due to the number of in- or output links of an area. We show that learning of semantic relationships between words and the objects and actions these symbols are used to speak about, leads to the formation of distributed circuits, which all include neuronal material in connector hub areas bridging between sensory and motor cortical systems. Therefore, these connector hub areas acquire a role as semantic hubs. By differentially reaching into motor or visual areas, the cortical distributions of the emergent 'semantic circuits' reflect aspects of the represented symbols' meaning, thus explaining category-specificity. The improved connectivity structure of our model entails a degree of category-specificity even in the 'semantic hubs' of the model. The relative time-course of activation of these areas is typically fast and near-simultaneous, with semantic hubs central to the network structure activating before modality-preferential areas carrying semantic information. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Combining Temporal and Spectral Information with Spatial Mapping to Identify Differences between Phonological and Semantic Networks: A Magnetoencephalographic Approach

PubMed Central

McNab, Fiona; Hillebrand, Arjan; Swithenby, Stephen J.; Rippon, Gina

2012-01-01

Early, lesion-based models of language processing suggested that semantic and phonological processes are associated with distinct temporal and parietal regions respectively, with frontal areas more indirectly involved. Contemporary spatial brain mapping techniques have not supported such clear-cut segregation, with strong evidence of activation in left temporal areas by both processes and disputed evidence of involvement of frontal areas in both processes. We suggest that combining spatial information with temporal and spectral data may allow a closer scrutiny of the differential involvement of closely overlapping cortical areas in language processing. Using beamforming techniques to analyze magnetoencephalography data, we localized the neuronal substrates underlying primed responses to nouns requiring either phonological or semantic processing, and examined the associated measures of time and frequency in those areas where activation was common to both tasks. Power changes in the beta (14–30 Hz) and gamma (30–50 Hz) frequency bands were analyzed in pre-selected time windows of 350–550 and 500–700 ms In left temporal regions, both tasks elicited power changes in the same time window (350–550 ms), but with different spectral characteristics, low beta (14–20 Hz) for the phonological task and high beta (20–30 Hz) for the semantic task. In frontal areas (BA10), both tasks elicited power changes in the gamma band (30–50 Hz), but in different time windows, 500–700 ms for the phonological task and 350–550 ms for the semantic task. In the left inferior parietal area (BA40), both tasks elicited changes in the 20–30 Hz beta frequency band but in different time windows, 350–550 ms for the phonological task and 500–700 ms for the semantic task. Our findings suggest that, where spatial measures may indicate overlapping areas of involvement, additional beamforming techniques can demonstrate differential activation in time and frequency domains. PMID:22908001

The influence of rTMS over prefrontal and motor areas in a morphological task: grammatical vs. semantic effects.

PubMed

Gerfo, Emanuele Lo; Oliveri, Massimiliano; Torriero, Sara; Salerno, Silvia; Koch, Giacomo; Caltagirone, Carlo

2008-01-31

We investigated the differential role of two frontal regions in the processing of grammatical and semantic knowledge. Given the documented specificity of the prefrontal cortex for the grammatical class of verbs, and of the primary motor cortex for the semantic class of action words, we sought to investigate whether the prefrontal cortex is also sensitive to semantic effects, and whether the motor cortex is also sensitive to grammatical class effects. We used repetitive transcranial magnetic stimulation (rTMS) to suppress the excitability of a portion of left prefontal cortex (first experiment) and of the motor area (second experiment). In the first experiment we found that rTMS applied to the left prefrontal cortex delays the processing of action verbs' retrieval, but is not critical for retrieval of state verbs and state nouns. In the second experiment we found that rTMS applied to the left motor cortex delays the processing of action words, both name and verbs, while it is not critical for the processing of state words. These results support the notion that left prefrontal and motor cortex are involved in the process of action word retrieval. Left prefrontal cortex subserves processing of both grammatical and semantic information, whereas motor cortex contributes to the processing of semantic representation of action words without any involvement in the representation of grammatical categories.

Handedness and language learning disability differentially distribute in progressive aphasia variants.

PubMed

Miller, Zachary A; Mandelli, Maria Luisa; Rankin, Katherine P; Henry, Maya L; Babiak, Miranda C; Frazier, Darvis T; Lobach, Iryna V; Bettcher, Brianne M; Wu, Teresa Q; Rabinovici, Gil D; Graff-Radford, Neill R; Miller, Bruce L; Gorno-Tempini, Maria Luisa

2013-11-01

Primary progressive aphasia is a neurodegenerative clinical syndrome that presents in adulthood with an isolated, progressive language disorder. Three main clinical/anatomical variants have been described, each associated with distinctive pathology. A high frequency of neurodevelopmental learning disability in primary progressive aphasia has been reported. Because the disorder is heterogeneous with different patterns of cognitive, anatomical and biological involvement, we sought to identify whether learning disability had a predilection for one or more of the primary progressive aphasia subtypes. We screened the University of California San Francisco Memory and Aging Center's primary progressive aphasia cohort (n = 198) for history of language-related learning disability as well as hand preference, which has associations with learning disability. The study included logopenic (n = 48), non-fluent (n = 54) and semantic (n = 96) variant primary progressive aphasias. We investigated whether the presence of learning disability or non-right-handedness was associated with differential effects on demographic, neuropsychological and neuroimaging features of primary progressive aphasia. We showed that a high frequency of learning disability was present only in the logopenic group (χ(2) = 15.17, P < 0.001) and (χ(2) = 11.51, P < 0.001) compared with semantic and non-fluent populations. In this group, learning disability was associated with earlier onset of disease, more isolated language symptoms, and more focal pattern of left posterior temporoparietal atrophy. Non-right-handedness was instead over-represented in the semantic group, at nearly twice the prevalence of the general population (χ(2) = 6.34, P = 0.01). Within semantic variant primary progressive aphasia the right-handed and non-right-handed cohorts appeared homogeneous on imaging, cognitive profile, and structural analysis of brain symmetry. Lastly, the non-fluent group showed no increase in learning disability or non-right-handedness. Logopenic variant primary progressive aphasia and developmental dyslexia both manifest with phonological disturbances and posterior temporal involvement. Learning disability might confer vulnerability of this network to early-onset, focal Alzheimer's pathology. Left-handedness has been described as a proxy for atypical brain hemispheric lateralization. As non-right-handedness was increased only in the semantic group, anomalous lateralization mechanisms might instead be related to frontotemporal lobar degeneration with abnormal TARDBP. Taken together, this study suggests that neurodevelopmental signatures impart differential trajectories towards neurodegenerative disease.

Perceptions of Family Dependence by the Physically Disabled

ERIC Educational Resources Information Center

Thomas, Kenneth R.; Britton, Jean O.

1973-01-01

The ralationship between six demographic characteristics and perceptions of family dependence were investigated for 170 physically disabled adults using Osgood's semantic differential technique. Implications of these findings for rehabilitation practice and further research are presented. (Author)

A pilot study measuring changes in student impressions before and after clinical training using a questionnaire based on the semantic differential technique.

PubMed

Tamura, Naomi; Terashita, Takayoshi; Ogasawara, Katsuhiko

2013-01-01

Students with a positive impression of their studies can become more motivated. This study measured the learning impact of clinical training by comparing student impressions before and after clinical training. The study included 32 students of radiological technology in their final year with the Division of Radiological Science and Technology, Department of Health Sciences, School of Medicine, Hokkaido University. To measure student impressions of x-ray examination training, we developed a questionnaire using the semantic differential technique. The resulting factor analysis identified 2 factors that accounted for 44.9% of the 10 bipolar adjective scales. Factor 1 represented a "resistance" impression of x-ray examination training, and factor 2 represented a "responsibility" impression. The differences in factor scores before and after the clinical training suggest that student impressions are affected by clinical training.

Comparing nouns and verbs in a lexical task.

PubMed

Cordier, Françoise; Croizet, Jean-Claude; Rigalleau, François

2013-02-01

We analyzed the differential processing of nouns and verbs in a lexical decision task. Moderate and high-frequency nouns and verbs were compared. The characteristics of our material were specified at the formal level (number of letters and syllables, number of homographs, orthographic neighbors, frequency and age of acquisition), and at the semantic level (imagery, number and strength of associations, number of meanings, context dependency). A regression analysis indicated a classical frequency effect and a word-type effect, with latencies for verbs being slower than for nouns. The regression analysis did not permit the conclusion that semantic effects were involved (particularly imageability). Nevertheless, the semantic opposition between nouns as prototypical representations of objects, and verbs as prototypical representation of actions was not tested in this experiment and remains a good candidate explanation of the response time discrepancies between verbs and nouns.

A meta-analysis of fMRI studies on Chinese orthographic, phonological, and semantic processing.

PubMed

Wu, Chiao-Yi; Ho, Moon-Ho Ringo; Chen, Shen-Hsing Annabel

2012-10-15

A growing body of neuroimaging evidence has shown that Chinese character processing recruits differential activation from alphabetic languages due to its unique linguistic features. As more investigations on Chinese character processing have recently become available, we applied a meta-analytic approach to summarize previous findings and examined the neural networks for orthographic, phonological, and semantic processing of Chinese characters independently. The activation likelihood estimation (ALE) method was used to analyze eight studies in the orthographic task category, eleven in the phonological and fifteen in the semantic task categories. Converging activation among three language-processing components was found in the left middle frontal gyrus, the left superior parietal lobule and the left mid-fusiform gyrus, suggesting a common sub-network underlying the character recognition process regardless of the task nature. With increasing task demands, the left inferior parietal lobule and the right superior temporal gyrus were specialized for phonological processing, while the left middle temporal gyrus was involved in semantic processing. Functional dissociation was identified in the left inferior frontal gyrus, with the posterior dorsal part for phonological processing and the anterior ventral part for semantic processing. Moreover, bilateral involvement of the ventral occipito-temporal regions was found for both phonological and semantic processing. The results provide better understanding of the neural networks underlying Chinese orthographic, phonological, and semantic processing, and consolidate the findings of additional recruitment of the left middle frontal gyrus and the right fusiform gyrus for Chinese character processing as compared with the universal language network that has been based on alphabetic languages. Copyright © 2012 Elsevier Inc. All rights reserved.

Neural underpinnings for model-oriented therapy of aphasic word production.

PubMed

Abel, Stefanie; Weiller, Cornelius; Huber, Walter; Willmes, Klaus

2014-05-01

Model-oriented therapies of aphasic word production have been shown to be effective, with item-specific therapy effects being larger than generalisation effects for untrained items. However, it remains unclear whether semantic versus phonological therapy lead to differential effects, depending on type of lexical impairment. Functional imaging studies revealed that mainly left-hemisphere, perisylvian brain areas were involved in successful therapy-induced recovery of aphasic word production. However, the neural underpinnings for model-oriented therapy effects have not received much attention yet. We aimed at identifying brain areas indicating (1) general therapy effects using a naming task measured by functional magnetic resonance imaging (fMRI) in 14 patients before and after a 4-week naming therapy, which comprised increasing semantic and phonological cueing-hierarchies. We also intended to reveal differential effects (2) of training versus generalisation, (3) of therapy methods, and (4) of type of impairment as assessed by the connectionist Dell model. Training effects were stronger than generalisation effects, even though both were significant. Furthermore, significant impairment-specific therapy effects were observed for patients with phonological disorders (P-patients). (1) Left inferior frontal gyrus, pars opercularis (IFGoper), was a positive predictor of therapy gains while the right caudate was a negative predictor. Moreover, less activation decrease due to therapy in left-hemisphere temporo-parietal language areas was positively correlated with therapy gains. (2) Naming of trained compared to untrained words yielded less activation decrease in left superior temporal gyrus (STG) and precuneus, bilateral thalamus, and right caudate due to therapy. (3) Differential therapy effects could be detected in the right superior parietal lobule for the semantic method, and in regions involving bilateral anterior and mid cingulate, right precuneus, and left middle/superior frontal gyrus for the phonological method. (4) Impairment-specific changes of activation were found for P-patients in left IFGoper. Patients with semantic disorders (S-patients) relied on right frontal areas involving IFG, pars triangularis. After therapy, they revealed less activation decrease in areas involving left STG, caudate, paracentral lobule, and right rolandic operculum. Regarding naming performance, the present study corroborates previous findings on training and generalisation effects and reveals differential therapy effects for P-patients. Moreover, brain imaging results confirm a predominance of (1) general effects in the left brain hemisphere. (2) Brain regions related to visual strategy, monitoring/feedback, and articulatory patterns were characteristic for the familiar trained items. (3) Distinct regions associated with strategies, monitoring capacities, and linguistic information indicate the specific therapeutic influence on word retrieval. (4) While P-patients relied more on preserved phonological functions in the left hemisphere, S-patients revealed right-sided compensation of semantic processing as well as increased strategic efforts in both hemispheres. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

The semantics of prosody: acoustic and perceptual evidence of prosodic correlates to word meaning.

PubMed

Nygaard, Lynne C; Herold, Debora S; Namy, Laura L

2009-01-01

This investigation examined whether speakers produce reliable prosodic correlates to meaning across semantic domains and whether listeners use these cues to derive word meaning from novel words. Speakers were asked to produce phrases in infant-directed speech in which novel words were used to convey one of two meanings from a set of antonym pairs (e.g., big/small). Acoustic analyses revealed that some acoustic features were correlated with overall valence of the meaning. However, each word meaning also displayed a unique acoustic signature, and semantically related meanings elicited similar acoustic profiles. In two perceptual tests, listeners either attempted to identify the novel words with a matching meaning dimension (picture pair) or with mismatched meaning dimensions. Listeners inferred the meaning of the novel words significantly more often when prosody matched the word meaning choices than when prosody mismatched. These findings suggest that speech contains reliable prosodic markers to word meaning and that listeners use these prosodic cues to differentiate meanings. That prosody is semantic suggests a reconceptualization of traditional distinctions between linguistic and nonlinguistic properties of spoken language. Copyright © 2009 Cognitive Science Society, Inc.

Disorganised schizotypy is selectively associated with poorer semantic processing in non-clinical individuals.

PubMed

Tan, Eric Josiah; Rossell, Susan Lee

2017-10-01

The nature and severity of semantic memory (SM) impairments in schizophrenia has been related to symptoms, mainly formal thought disorder (FTD), and other clinical factors like length of illness. Symptom-related studies in schizophrenia are often confounded by clinical factors, for example medication and hospitalisations. We completed a schizotypy analogue study to examine the relationship between SM processing and FTD using an analogue schizotypy score referred to as cognitive disorganisation. Sixty individuals without a history of mental illness (M=22.92, SD=2.70) completed a schizotypy questionnaire and three semantic tasks - naming pictures, category fluency and semantic priming. Only decreasing fluency was associated with increasing cognitive disorganisation scores (p=0.029). In line with the prevailing dyssemantic theories, the results highlight that cognitive disorganisation is associated with some difficulties in SM processes, though not all. The observed differential relationships of SM processes to disorganised schizotypy are discussed in relation to previous work, and in terms of potential developmental trajectories for SM impairment in schizophrenia. Copyright © 2017 Elsevier B.V. All rights reserved.

I see/hear what you mean: semantic activation in visual word recognition depends on perceptual attention.

PubMed

Connell, Louise; Lynott, Dermot

2014-04-01

How does the meaning of a word affect how quickly we can recognize it? Accounts of visual word recognition allow semantic information to facilitate performance but have neglected the role of modality-specific perceptual attention in activating meaning. We predicted that modality-specific semantic information would differentially facilitate lexical decision and reading aloud, depending on how perceptual attention is implicitly directed by each task. Large-scale regression analyses showed the perceptual modalities involved in representing a word's referent concept influence how easily that word is recognized. Both lexical decision and reading-aloud tasks direct attention toward vision, and are faster and more accurate for strongly visual words. Reading aloud additionally directs attention toward audition and is faster and more accurate for strongly auditory words. Furthermore, the overall semantic effects are as large for reading aloud as lexical decision and are separable from age-of-acquisition effects. These findings suggest that implicitly directing perceptual attention toward a particular modality facilitates representing modality-specific perceptual information in the meaning of a word, which in turn contributes to the lexical decision or reading-aloud response.

Semantic relations differentially impact associative recognition memory: electrophysiological evidence.

PubMed

Kriukova, Olga; Bridger, Emma; Mecklinger, Axel

2013-10-01

Though associative recognition memory is thought to rely primarily on recollection, recent research indicates that familiarity might also make a substantial contribution when to-be-learned items are integrated into a coherent structure by means of an existing semantic relation. It remains unclear how different types of semantic relations, such as categorical (e.g., dancer-singer) and thematic (e.g., dancer-stage) relations might affect associative recognition, however. Using event-related potentials (ERPs), we addressed this question by manipulating the type of semantic link between paired words in an associative recognition memory experiment. An early midfrontal old/new effect, typically linked to familiarity, was observed across the relation types. In contrast, a robust left parietal old/new effect was found in the categorical condition only, suggesting a clear contribution of recollection to associative recognition for this kind of pairs. One interpretation of this pattern is that familiarity was sufficiently diagnostic for associative recognition of thematic relations, which could result from the integrative nature of the thematic relatedness compared to the similarity-based nature of categorical pairs. The present study suggests that the extent to which recollection and familiarity are involved in associative recognition is at least in part determined by the properties of semantic relations between the paired associates. Copyright © 2013 Elsevier Inc. All rights reserved.

Event Congruency Enhances Episodic Memory Encoding through Semantic Elaboration and Relational Binding

PubMed Central

Staresina, Bernhard P.; Gray, James C.

2009-01-01

Behavioral research consistently shows that congruous events, that is, events whose constituent elements match along some specific dimension, are better remembered than incongruous events. Although it has been speculated that this “congruency subsequent memory effect” (cSME) results from enhanced semantic elaboration, empirical evidence for this account is lacking. Here, we report a set of behavioral and neuroimaging experiments demonstrating that congruous events engage regions along the left inferior frontal gyrus (LIFG)—consistently related to semantic elaboration—to a significantly greater degree than incongruous events, providing evidence in favor of this hypothesis. Critically, we additionally report 3 novel findings in relation to event congruency: First, congruous events yield superior memory not only for a given study item but also for associated source details. Second, the cSME is evident not only for events that matched a semantic context but also for those that matched a subjective aesthetic schema. Finally, functional magnetic resonance imaging brain/behavior correlation analysis reveals a strong link between 1) across-subject variation in the magnitude of the cSME and 2) differential right hippocampal activation, suggesting that episodic memory for congruous events is effectively bolstered by the extent to which semantic associations are generated and relationally integrated via LIFG-hippocampal–encoding mechanisms. PMID:18820289

Lexical Semantics and Irregular Inflection

PubMed Central

Huang, Yi Ting; Pinker, Steven

2010-01-01

Whether a word has an irregular inflection does not depend on its sound alone: compare lie-lay (recline) and lie-lied (prevaricate). Theories of morphology, particularly connectionist and symbolic models, disagree on which nonphonological factors are responsible. We test four possibilities: (1) Lexical effects, in which two lemmas differ in whether they specify an irregular form; (2) Semantic effects, in which the semantic features of a word become associated with regular or irregular forms; (3) Morphological structure effects, in which a word with a headless structure (e.g., a verb derived from a noun) blocks access to a stored irregular form; (4) Compositionality effects, in which the stored combination of an irregular word’s meaning (e.g., the verb’s inherent aspect) with the meaning of the inflection (e.g., pastness) doesn’t readily transfer to new senses with different combinations of such meanings. In four experiments, speakers were presented with existing and novel verbs and asked to rate their past-tense forms, semantic similarities, grammatical structure, and aspectual similarities. We found (1) an interaction between semantic and phonological similarity, coinciding with reported strategies of analogizing to known verbs and implicating lexical effects; (2) weak and inconsistent effects of semantic similarity; (3) robust effects of morphological structure, and (4) robust effects of aspectual compositionality. Results are consistent with theories of language that invoke lexical entries and morphological structure, and which differentiate the mode of storage of regular and irregular verbs. They also suggest how psycholinguistic processes have shaped vocabulary structure over history. PMID:21151703

Priming deficiency in male subjects at risk for alcoholism: the N4 during a lexical decision task.

PubMed

Roopesh, Bangalore N; Rangaswamy, Madhavi; Kamarajan, Chella; Chorlian, David B; Stimus, Arthur; Bauer, Lance O; Rohrbaugh, John; O'Connor, Sean J; Kuperman, Samuel; Schuckit, Marc; Porjesz, Bernice

2009-12-01

While there is extensive literature on the relationship between the P3 component of event-related potentials (ERPs) and risk for alcoholism, there are few published studies regarding other potentially important ERP components. One important candidate is the N4(00) component in the context of semantic processing, as abnormalities in this component have been reported for adult alcoholics. A semantic priming task was administered to nonalcohol dependent male offspring (18 to 25 years) of alcoholic fathers [high risk (HR) n = 23] and nonalcoholic fathers [low risk (LR) n = 28] to study whether the 2 groups differ in terms of the N4 component. Subjects were presented with 150 words and 150 nonwords. Among the words, 50 words (primed) were preceded by their antonyms (prime, n = 50), whereas the remaining 50 words were unprimed. For the analysis, N4 amplitude and latency as well as behavioral measures for the primed and unprimed words were considered. A significant interaction effect was observed between semantic condition and group, where HR subjects did not show N4 attenuation for primed stimuli. The lack of N4 attenuation to primed stimuli and/or inability to differentiate between primed and unprimed stimuli, without latency and reaction time being affected, suggest deficits in semantic priming, especially in semantic expectancy and/or postlexical semantic processing in HR male offspring. Further, it indicates that it might be an electrophysiological endophenotype that reflects genetic vulnerability to develop alcoholism.

Electrophysiological signatures of event words: Dissociating syntactic and semantic category effects in lexical processing.

PubMed

Lapinskaya, Natalia; Uzomah, Uchechukwu; Bedny, Marina; Lau, Ellen

2016-12-01

Numerous theories have been proposed regarding the brain's organization and retrieval of lexical information. Neurophysiological dissociations in processing different word classes, particularly nouns and verbs, have been extensively documented, supporting the contribution of grammatical class to lexical organization. However, the contribution of semantic properties to these processing differences is still unresolved. We aim to isolate this contribution by comparing ERPs to verbs (e.g. wade), object nouns (e.g. cookie), and event nouns (e.g. concert) in a paired similarity judgment task, as event nouns share grammatical category with object nouns but some semantic properties with verbs. We find that event nouns pattern with verbs in eliciting a more positive response than object nouns across left anterior electrodes 300-500ms after word presentation. This time-window has been strongly linked to lexical-semantic access by prior electrophysiological work. Thus, the similarity of the response to words referring to concepts with more complex participant structure and temporal continuity extends across grammatical class (event nouns and verbs), and contrasts with the words that refer to objects (object nouns). This contrast supports a semantic, as well as syntactic, contribution to the differential neural organization and processing of lexical items. We also observed a late (500-800ms post-stimulus) posterior positivity for object nouns relative to event nouns and verbs at the second word of each pair, which may reflect the impact of semantic properties on the similarity judgment task. Copyright © 2016 Elsevier Ltd. All rights reserved.

Research in Human Sexuality Education

ERIC Educational Resources Information Center

Carmichael, Joan; And Others

1977-01-01

Medical students' attitudes towards concepts in sexuality before and after a five-day sexuality course were tested at the University of Miami School of Medicine and evaluated with Osgood's Semantic Differential. Concepts rated were "my sexuality,""masturbation,""homosexuality," and "my role in understanding…

The use of semantic- and phonological-based feature approaches to treat naming deficits in aphasia.

PubMed

Hashimoto, Naomi

2012-06-01

The aim of the study was to compare approaches highlighting either semantic or phonological features to treat naming deficits in aphasia. Treatment focused on improving picture naming. An alternating treatments design was used with a multiple baseline design across stimuli to examine effects of both approaches in two participants with varying degrees of anomia. The features approaches were modified in that three, rather than six, features were used. Significant differential effects were found across participants; this appeared to be a function of each participant's strengths or preferences over the course of treatment. Modest generalization effects were obtained for one participant. Naming error analyses revealed patterns suggestive of increased lexical access for both participants. These findings provide evidence that using a modified features-based protocol can improve naming when incorporating both semantic and phonological feature cues. Naming error patterns can provide additional evidence of improved naming during treatment.

Levels of word processing and incidental memory: dissociable mechanisms in the temporal lobe.

PubMed

Castillo, E M; Simos, P G; Davis, R N; Breier, J; Fitzgerald, M E; Papanicolaou, A C

2001-11-16

Word recall is facilitated when deep (e.g. semantic) processing is applied during encoding. This fact raises the question of the existence of specific brain mechanisms supporting different levels of information processing that can modulate incidental memory performance. In this study we obtained spatiotemporal brain activation profiles, using magnetic source imaging, from 10 adult volunteers as they performed a shallow (phonological) processing task and a deep (semantic) processing task. When phonological analysis of the word stimuli into their constituent phonemes was required, activation was largely restricted to the posterior portion of the left superior temporal gyrus (area 22). Conversely, when access to lexical/semantic representations was required, activation was found predominantly in the left middle temporal gyrus and medial temporal cortex. The differential engagement of each mechanism during word encoding was associated with dramatic changes in subsequent incidental memory performance.

Elucidating semantic disorganisation from a word comprehension task: do patients with schizophrenia and bipolar disorder show differential processing of nouns, verbs and adjectives?

PubMed

Rossell, Susan L; Batty, Rachel A

2008-07-01

Memory deficits have been reported in schizophrenia and bipolar disorder. However, the precise impact of semantic memory deficits on word comprehension, particularly across grammatical categories, has not been adequately investigated in these disorders. Furthermore, previous studies examining semantic memory have predominantly been designed so that most healthy controls perform at ceiling, questioning the validity of observed differences between patient and control groups. A new word definition task examined word comprehension across grammatical categories, i.e. nouns, verbs and adjectives, and was designed to overcome the ceiling effect. It was administered to 32 schizophrenia patients, 28 bipolar disorder patients and 32 matched healthy controls. Schizophrenia patients had a global impairment on the task but bipolar patients were only impaired on a recognition memory component. Word comprehension, however, across grammatical categories was comparable across groups.

Serial position effects in semantic memory: reconstructing the order of verses of hymns.

PubMed

Maylor, Elizabeth A

2002-12-01

Serial position effects (primacy and recency) have been consistently demonstrated in both short- and long-term episodic memory tasks. The search for corresponding effects in semantic memory tasks (e.g., reconstructing the order of U.S. presidents) has been confounded by factors such as differential exposure to stimuli. In the present study, the stimuli were six-verse hymns that would have been sung from the first to the last verse by churchgoers on numerous occasions. Participants were presented with the verses of each hymn in random order and were required to reconstruct the correct order. Primacy and recency effects were significantly more evident for churchgoers than for nonchurchgoers. Moreover, error gradients were steeper than chance for churchgoers but not for nonchurchgoers; in other words, churchgoers' errors were more likely to be close to the correct position than further away. These findings provide the first unequivocal demonstration of serial position effects in semantic memory.

Memory and emotion processing performance contributes to the diagnosis of non-semantic primary progressive aphasia syndromes.

PubMed

Piguet, Olivier; Leyton, Cristian E; Gleeson, Liam D; Hoon, Chris; Hodges, John R

2015-01-01

The two non-semantic variants of primary progressive aphasia (PPA), nonfluent/agrammatic PPA (nfv-PPA) and logopenic variant PPA (lv-PPA), share language features despite their different underlying pathology, and may be difficult to distinguish for non-language experts. To improve diagnostic accuracy of nfv-PPA and lv-PPA using tasks measuring non-language cognition and emotion processing. Thirty-eight dementia patients meeting diagnostic criteria for PPA (nfv-PPA 20, lv-PPA 18) and 21 matched healthy Controls underwent a comprehensive assessment of cognition and emotion processing, as well as a high-resolution structural MRI and a PiB-PET scan, a putative biomarker of Alzheimer's disease. Task performances were compared between the groups and those found to differ significantly were entered into a logistic regression analysis. Analyses revealed a double dissociation between nfv-PPA and lv-PPA. nfv-PPA exhibited significant emotion processing disturbance compared to lv-PPA and Controls. In contrast, only the lv-PPA group was significantly impaired on tasks of episodic memory. Logistic regression analyses showed that 87% of patients were correctly classified using emotion processing and episodic memory composite scores, together with a measure of visuospatial ability. Non-language presenting features can help differentiate between the two non-semantic PPA syndromes, with a double dissociation observed on tasks of episodic memory and emotion processing. Based on performance on these tasks, we propose a decision tree as a complementary method to differentiate between the two non-semantic variants. These findings have important clinical implications, with identification of patients who may potentially benefit existing therapeutic interventions currently available for Alzheimer's disease.

Naive Physics, Event Perception, Lexical Semantics, and Language Acquisition

DTIC Science & Technology

1993-04-01

settings within a framework of universal grammar. His central claim is that children use primarily unembedded material as evidence for the parameter...differentiate embedded from unembedded material. Deriving such structural information requires that the learner determine constituent order prior io ot her

The Development and Evaluation of Industrial Case Studies to Support a New Laboratory Course in Electrical Engineering.

ERIC Educational Resources Information Center

Bolton, B.; Adderley, K. J.

1978-01-01

After viewing videotaped case studies indicating the relevance of electrical laboratory work to professional engineers, student attitudes showed a positive improvement toward laboratory work. Semantic differential tests, questionnaires, and interviews were used. (Author/MH)

DIMENSIONS OF TEACHER'S ATTITUDES TOWARD INSTRUCTIONAL MEDIA.

ERIC Educational Resources Information Center

TOBIAS, SIGMUND

TEACHERS' RATINGS ON SIX 7-POINT SEMANTIC DIFFERENTIAL SCALES (GOOD-BAD, WORTHLESS-VALUABLE, FAIR-UNFAIR, MEANINGLESS-MEANINGFUL, WISE-FOOLISH, DISREPUTABLE-REPUTABLE) WERE OBTAINED FOR THE FOLLOWING TERMS--AUTOMATED INSTRUCTION, SELF-INSTRUCTIONAL PROGRAM, TEACHING MACHINE, MECHANIZED TUTOR, PROGRAMED TEST, PROGRAMED INSTRUCTION, TUTOR TEXT, WORK…

Measuring environmental attitudes of elementary school students

Treesearch

John C. Benjamin; George H. Moeller; Douglas A. Morrison

1977-01-01

A modified semantic differential was developed to measure environmental attitudes of sixth-graders. Classes were selected to represent different socioeconomic and residence backgrounds and degrees of previous exposure to structured environmental programs. Results indicate that: exposure to environmental education fosters favorable environmental attitudes; socioeconomic...

Patient-Therapist Identification in Relation to Both Patient and Therapist Variables and Therapy Outcome

ERIC Educational Resources Information Center

Melnick, Barry

1972-01-01

The results of the study confirmed the hypothesis that greater patient identification with the therapist, as defined by increased similarity between the patient's and therapist's semantic differential ratings, moderately correlated with more successful therapy outcome. (Author)

Multimodal Feature Integration in the Angular Gyrus during Episodic and Semantic Retrieval

PubMed Central

Bonnici, Heidi M.; Richter, Franziska R.; Yazar, Yasemin

2016-01-01

Much evidence from distinct lines of investigation indicates the involvement of angular gyrus (AnG) in the retrieval of both episodic and semantic information, but the region's precise function and whether that function differs across episodic and semantic retrieval have yet to be determined. We used univariate and multivariate fMRI analysis methods to examine the role of AnG in multimodal feature integration during episodic and semantic retrieval. Human participants completed episodic and semantic memory tasks involving unimodal (auditory or visual) and multimodal (audio-visual) stimuli. Univariate analyses revealed the recruitment of functionally distinct AnG subregions during the retrieval of episodic and semantic information. Consistent with a role in multimodal feature integration during episodic retrieval, significantly greater AnG activity was observed during retrieval of integrated multimodal episodic memories compared with unimodal episodic memories. Multivariate classification analyses revealed that individual multimodal episodic memories could be differentiated in AnG, with classification accuracy tracking the vividness of participants' reported recollections, whereas distinct unimodal memories were represented in sensory association areas only. In contrast to episodic retrieval, AnG was engaged to a statistically equivalent degree during retrieval of unimodal and multimodal semantic memories, suggesting a distinct role for AnG during semantic retrieval. Modality-specific sensory association areas exhibited corresponding activity during both episodic and semantic retrieval, which mirrored the functional specialization of these regions during perception. The results offer new insights into the integrative processes subserved by AnG and its contribution to our subjective experience of remembering. SIGNIFICANCE STATEMENT Using univariate and multivariate fMRI analyses, we provide evidence that functionally distinct subregions of angular gyrus (AnG) contribute to the retrieval of episodic and semantic memories. Our multivariate pattern classifier could distinguish episodic memory representations in AnG according to whether they were multimodal (audio-visual) or unimodal (auditory or visual) in nature, whereas statistically equivalent AnG activity was observed during retrieval of unimodal and multimodal semantic memories. Classification accuracy during episodic retrieval scaled with the trial-by-trial vividness with which participants experienced their recollections. Therefore, the findings offer new insights into the integrative processes subserved by AnG and how its function may contribute to our subjective experience of remembering. PMID:27194327

Multimodal Feature Integration in the Angular Gyrus during Episodic and Semantic Retrieval.

PubMed

Bonnici, Heidi M; Richter, Franziska R; Yazar, Yasemin; Simons, Jon S

2016-05-18

Much evidence from distinct lines of investigation indicates the involvement of angular gyrus (AnG) in the retrieval of both episodic and semantic information, but the region's precise function and whether that function differs across episodic and semantic retrieval have yet to be determined. We used univariate and multivariate fMRI analysis methods to examine the role of AnG in multimodal feature integration during episodic and semantic retrieval. Human participants completed episodic and semantic memory tasks involving unimodal (auditory or visual) and multimodal (audio-visual) stimuli. Univariate analyses revealed the recruitment of functionally distinct AnG subregions during the retrieval of episodic and semantic information. Consistent with a role in multimodal feature integration during episodic retrieval, significantly greater AnG activity was observed during retrieval of integrated multimodal episodic memories compared with unimodal episodic memories. Multivariate classification analyses revealed that individual multimodal episodic memories could be differentiated in AnG, with classification accuracy tracking the vividness of participants' reported recollections, whereas distinct unimodal memories were represented in sensory association areas only. In contrast to episodic retrieval, AnG was engaged to a statistically equivalent degree during retrieval of unimodal and multimodal semantic memories, suggesting a distinct role for AnG during semantic retrieval. Modality-specific sensory association areas exhibited corresponding activity during both episodic and semantic retrieval, which mirrored the functional specialization of these regions during perception. The results offer new insights into the integrative processes subserved by AnG and its contribution to our subjective experience of remembering. Using univariate and multivariate fMRI analyses, we provide evidence that functionally distinct subregions of angular gyrus (AnG) contribute to the retrieval of episodic and semantic memories. Our multivariate pattern classifier could distinguish episodic memory representations in AnG according to whether they were multimodal (audio-visual) or unimodal (auditory or visual) in nature, whereas statistically equivalent AnG activity was observed during retrieval of unimodal and multimodal semantic memories. Classification accuracy during episodic retrieval scaled with the trial-by-trial vividness with which participants experienced their recollections. Therefore, the findings offer new insights into the integrative processes subserved by AnG and how its function may contribute to our subjective experience of remembering. Copyright © 2016 Bonnici, Richter, et al.

Patterns of brain activity during a semantic task differentiate normal aging from early Alzheimer's disease.

PubMed

McGeown, William Jonathan; Shanks, Michael Fraser; Forbes-McKay, Katrina Elaine; Venneri, Annalena

2009-09-30

In a study of the effects of normal and pathological aging on semantic-related brain activity, 29 patients with Alzheimer's disease (AD) and 19 controls subjects (10 young and 9 older controls) performed a version of the Pyramids and Palm Trees Test that had been adapted for use during functional magnetic resonance imaging (fMRI). Young and older controls activated the left inferior and middle frontal gyri, precuneus and superior parietal lobule. Right frontal and left temporal cortices were activated only in the young. The AD group activated only the left prefrontal and cingulate cortex. Separate analyses of high- and low-performing AD subgroups showed a similar pattern of activation in the left frontal lobe, although activiation was more widespread in low performers. High performers significantly deactivated anterior midline frontal structures, however, while low performers did not. When the older adult and AD groups were combined, there was a significant positive correlation between left frontal and parietal activation and Mini-Mental State Examination (MMSE) score (covarying for age), suggesting a disease effect. A significant negative correlation between activation in the left temporal cortex and age (covarying for MMSE score) reflected a possible age effect. These differential effects suggest that semantic activation paradigms might aid diagnosis in those cases for whom conventional assessments lack the necessary sensitivity to detect subtle changes.

Divergent Human Cortical Regions for Processing Distinct Acoustic-Semantic Categories of Natural Sounds: Animal Action Sounds vs. Vocalizations

PubMed Central

Webster, Paula J.; Skipper-Kallal, Laura M.; Frum, Chris A.; Still, Hayley N.; Ward, B. Douglas; Lewis, James W.

2017-01-01

A major gap in our understanding of natural sound processing is knowledge of where or how in a cortical hierarchy differential processing leads to categorical perception at a semantic level. Here, using functional magnetic resonance imaging (fMRI) we sought to determine if and where cortical pathways in humans might diverge for processing action sounds vs. vocalizations as distinct acoustic-semantic categories of real-world sound when matched for duration and intensity. This was tested by using relatively less semantically complex natural sounds produced by non-conspecific animals rather than humans. Our results revealed a striking double-dissociation of activated networks bilaterally. This included a previously well described pathway preferential for processing vocalization signals directed laterally from functionally defined primary auditory cortices to the anterior superior temporal gyri, and a less well-described pathway preferential for processing animal action sounds directed medially to the posterior insulae. We additionally found that some of these regions and associated cortical networks showed parametric sensitivity to high-order quantifiable acoustic signal attributes and/or to perceptual features of the natural stimuli, such as the degree of perceived recognition or intentional understanding. Overall, these results supported a neurobiological theoretical framework for how the mammalian brain may be fundamentally organized to process acoustically and acoustic-semantically distinct categories of ethologically valid, real-world sounds. PMID:28111538

Action-semantic and syntactic deficits in subjects at risk for Huntington's disease.

PubMed

García, Adolfo M; Bocanegra, Yamile; Herrera, Eduar; Pino, Mariana; Muñoz, Edinson; Sedeño, Lucas; Ibáñez, Agustín

2017-03-11

Frontostriatal networks play critical roles in grounding action semantics and syntactic skills. Indeed, their atrophy distinctively disrupts both domains, as observed in patients with Huntington's disease (HD) and Parkinson's disease, even during early disease stages. However, frontostriatal degeneration in these conditions may begin up to 15 years before the onset of clinical symptoms, opening avenues for pre-clinical detection via sensitive tasks. Such a mission is particularly critical in HD, given that patients' children have 50% chances of inheriting the disease. Against this background, we assessed whether deficits in the above-mentioned domains emerge in subjects at risk to develop HD. We administered tasks tapping action semantics, object semantics, and two forms of syntactic processing to 18 patients with HD, 19 asymptomatic first-degree relatives, and sociodemographically matched controls for each group. The patients evinced significant deficits in all tasks, but only those in the two target domains were independent of overall cognitive state. More crucially, relative to controls, the asymptomatic relatives were selectively impaired in action semantics and in the more complex syntactic task, with both patterns emerging irrespective of the subjects' overall cognitive state. Our findings highlight the relevance of these dysfunctions as potential prodromal biomarkers of HD. Moreover, they offer theoretical insights into the differential contributions of frontostriatal hubs to both domains while paving the way for innovations in diagnostic procedures. © 2017 The British Psychological Society.

The Stigma of Dying: Attitudes Toward the Terminally Ill

ERIC Educational Resources Information Center

Epley, Rita J.; McCaghy, Charles H.

1978-01-01

Using a range of semantic differential adjectives, 233 college students indicated attitudes toward young and old people who were healthy, ill, or terminally ill. Attitudes toward each state of health category separate into three factors: attitudes toward healthy, ill, and dying persons. (Author)

User Authentication from Web Browsing Behavior

DTIC Science & Technology

2013-05-01

ourselves with a cognitive personal fingerprint. Attribution is broadly defined as the assignment of an ef- fect to a cause. We differentiate between...reusable patterns of behavior. We encode the semantic and stylistic content Figure 4: Burstiness profile below 1 min aggregated across all sessions for

Naming and verbal learning in adults with Alzheimer's disease, mild cognitive impairment and in healthy aging, with low educational levels.

PubMed

Hübner, Lilian Cristine; Loureiro, Fernanda; Tessaro, Bruna; Siqueira, Ellen Cristina Gerner; Jerônimo, Gislaine Machado; Gomes, Irênio; Schilling, Lucas Porcello

2018-02-01

Language assessment seems to be an effective tool to differentiate healthy and cognitively impaired aging groups. This article discusses the impact of educational level on a naming task, on a verbal learning with semantic cues task and on the MMSE in healthy aging adults at three educational levels (very low, low and high) as well as comparing two clinical groups of very low (0-3 years) and low education (4-7 years) patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) with healthy controls. The participants comprised 101 healthy controls, 17 patients with MCI and 19 with AD. Comparisons between the healthy groups showed an education effect on the MMSE, but not on naming and verbal learning. However, the clinical groups were differentiated in both the naming and verbal learning assessment. The results support the assumption that the verbal learning with semantic cues task is a valid tool to diagnose MCI and AD patients, with no influence from education.

Semantic processing in connected speech at a uniformly early stage of autopsy-confirmed Alzheimer's disease.

PubMed

Ahmed, Samrah; de Jager, Celeste A; Haigh, Anne-Marie; Garrard, Peter

2013-01-01

The aim of the present study was to quantify the semantic content of connected speech produced by patients at a uniformly early stage of pathologically proven Alzheimer's disease (AD). A secondary aim was to establish whether semantic units were reduced globally, or whether there was a disproportionate reduction of specific classes of information. Discourse samples were obtained from 18 AD patients and 18 matched controls, all pathologically confirmed. Semantic unit identification was scored overall and for four subclasses: subjects, locations, objects, and actions. Idea density and efficiency were calculated. AD transcripts showed significantly reduced units overall, particularly actions and subjects, as well as reduced efficiency. Total semantic units and a combination of subject-, location-, and object-related units ("noun" units) correlated with the Expression subscore on the Cambridge Cognitive Examination (CAMCOG). Subject related units correlated with the CAMCOG Abstract Thinking scale. Logistic regression analyses confirmed that all measures that were lower in AD than controls were predictive of group membership. An exploratory comparison between units expressed mainly using nouns and those mainly using verbs showed that the latter was the stronger of these two predictors. The present study adds a lexico-semantic dimension to the linguistic profile based on discourse analysis in typical AD, recently described by the same authors. 2012, 83(11): 1056-1062). The suggestion of differential importance of verb and noun use in the present study may be related to the reduction in syntactic complexity that was reported, using the same set of discourse samples, in the earlier study.

Material specific lateralization of medial temporal lobe function: An fMRI investigation.

PubMed

Dalton, Marshall A; Hornberger, Michael; Piguet, Olivier

2016-03-01

The theory of material specific lateralization of memory function posits that left and right MTL regions are asymmetrically involved in mnemonic processing of verbal and nonverbal material respectively. Lesion and functional imaging (fMRI) studies provide robust evidence for a left MTL asymmetry in the verbal memory domain. Evidence for a right MTL/nonverbal asymmetry is not as robust. A handful of fMRI studies have investigated this issue but have generally utilised nonverbal stimuli which are amenable to semantic elaboration. This fMRI study aimed to investigate the neural correlates of recognition memory processing in 20 healthy young adults (mean age = 26 years) for verbal stimuli and nonverbal stimuli that were specifically designed to minimize verbalisation. Analyses revealed that the neural correlates of recognition memory processing for verbal and nonverbal stimuli were differentiable and asymmetrically recruited the left and right MTL respectively. The right perirhinal cortex and hippocampus were preferentially involved in successful recognition memory of items devoid of semantic information. In contrast, the left anterior hippocampus was preferentially involved in successful recognition memory of stimuli which contained semantic meaning. These results suggest that the left MTL is preferentially involved in mnemonic processing of verbal/semantic information. In contrast, the right MTL is preferentially involved in visual/non-semantic mnemonic processing. We propose that during development, the left MTL becomes specialised for verbal mnemonic processing due to its proximity with left lateralised cortical language processing areas while visual/non-semantic mnemonic processing gets 'crowded out' to become predominantly, but not completely, the domain of the right MTL. © 2015 Wiley Periodicals, Inc.

BOLD response to semantic and syntactic processing during hypoglycemia is load-dependent.

PubMed

Schafer, Robin J; Page, Kathleen A; Arora, Jagriti; Sherwin, Robert; Constable, R Todd

2012-01-01

This study investigates how syntactic and semantic load factors impact sentence comprehension and BOLD signal under moderate hypoglycemia. A dual session, whole brain fMRI study was conducted on 16 healthy participants using the glucose clamp technique. In one session, they experienced insulin-induced hypoglycemia (plasma glucose at ∼50mg/dL); in the other, plasma glucose was maintained at euglycemic levels (∼100mg/dL). During scans subjects were presented with sentences of contrasting syntactic (embedding vs. conjunction) and semantic (reversibility vs. irreversibility) load. Semantic factors dominated the overall load effects on both performance (p<0.001) and BOLD response (p<0.01, corrected). Differential BOLD signal was observed in frontal, temporal, temporo-parietal and medio-temporal regions. Hypoglycemia and syntactic factors significantly impacted performance (p=0.002) and BOLD response (p<0.01, corrected) in the reversible clause conditions, more extensively in reversible-embedded than in reversible-conjoined clauses. Hypoglycemia resulted in a robust decrease in performance on reversible clauses and exerted attenuating effects on BOLD unselectively across cortical circuits. The dominance of reversibility in all measures underscores the distinction between the syntactic and semantic contrasts. The syntactic is based in a quantitative difference in algorithms interpreting embedded and conjoined structures. We suggest that the semantic is based in a qualitative difference between algorithmic mapping of arguments in reversible clauses and heuristic linking in irreversible clauses. Because heuristics drastically reduce resource demand, the operations they support would resist the load-dependent cognitive consequences of hypoglycemia. © 2011 Elsevier Inc. All rights reserved.

Olfactory memory in the old and very old: relations to episodic and semantic memory and APOE genotype.

PubMed

Larsson, Maria; Hedner, Margareta; Papenberg, Goran; Seubert, Janina; Bäckman, Lars; Laukka, Erika J

2016-02-01

The neuroanatomical organization that underlies olfactory memory is different from that of other memory types. The present work examines olfactory memory in an elderly population-based sample (Swedish National Study on Aging and Care in Kungsholmen) aged 60-100 years (n = 2280). We used structural equation modeling to investigate whether olfactory memory in old age is best conceptualized as a distinct category, differentiated from episodic and semantic memory. Further, potential olfactory dedifferentiation and genetic associations (APOE) to olfactory function in late senescence were investigated. Results are in support of a 3-factor solution where olfactory memory, as indexed by episodic odor recognition and odor identification, is modeled separately from episodic and semantic memory for visual and verbal information. Increasing age was associated with poorer olfactory memory performance, and observed age-related deficits were further exacerbated for carriers of the APOE ε4 allele; these effects tended to be larger for olfactory memory compared to episodic and semantic memory pertaining to other sensory systems (vision, auditory). Finally, stronger correlations between olfactory and episodic memory, indicating dedifferentiation, were observed in the older age groups. Copyright © 2016 Elsevier Inc. All rights reserved.

Further differentiating item and order information in semantic memory: students' recall of words from the "CU Fight Song", Harry Potter book titles, and Scooby Doo theme song.

PubMed

Overstreet, Michael F; Healy, Alice F; Neath, Ian

2017-01-01

University of Colorado (CU) students were tested for both order and item information in their semantic memory for the "CU Fight Song". Following an earlier study by Overstreet and Healy [(2011). Item and order information in semantic memory: Students' retention of the "CU fight song" lyrics. Memory & Cognition, 39, 251-259. doi: 10.3758/s13421-010-0018-3 ], a symmetrical bow-shaped serial position function (with both primacy and recency advantages) was found for reconstructing the order of the nine lines in the song, whereas a function with no primacy advantage was found for recalling a missing word from each line. This difference between order and item information was found even though students filled in missing words without any alternatives provided and missing words came from the beginning, middle, or end of each line. Similar results were found for CU students' recall of the sequence of Harry Potter book titles and the lyrics of the Scooby Doo theme song. These findings strengthen the claim that the pronounced serial position function in semantic memory occurs largely because of the retention of order, rather than item, information.

Dissociation between Semantic Representations for Motion and Action Verbs: Evidence from Patients with Left Hemisphere Lesions

PubMed Central

Taylor, Lawrence J.; Evans, Carys; Greer, Joanna; Senior, Carl; Coventry, Kenny R.; Ietswaart, Magdalena

2017-01-01

This multiple single case study contrasted left hemisphere stroke patients (N = 6) to healthy age-matched control participants (N = 15) on their understanding of action (e.g., holding, clenching) and motion verbs (e.g., crumbling, flowing). The tasks required participants to correctly identify the matching verb or associated picture. Dissociations on action and motion verb content depending on lesion site were expected. As predicted for verbs containing an action and/or motion content, modified t-tests confirmed selective deficits in processing motion verbs in patients with lesions involving posterior parietal and lateral occipitotemporal cortex. In contrast, deficits in verbs describing motionless actions were found in patients with more anterior lesions sparing posterior parietal and lateral occipitotemporal cortex. These findings support the hypotheses that semantic representations for action and motion are behaviorally and neuro-anatomically dissociable. The findings clarify the differential and critical role of perceptual and motor regions in processing modality-specific semantic knowledge as opposed to a supportive but not necessary role. We contextualize these results within theories from both cognitive psychology and cognitive neuroscience that make claims over the role of sensory and motor information in semantic representation. PMID:28261070

Patterns of linguistic and numerical performance in aphasia.

PubMed

Rath, Dajana; Domahs, Frank; Dressel, Katharina; Claros-Salinas, Dolores; Klein, Elise; Willmes, Klaus; Krinzinger, Helga

2015-02-04

Empirical research on the relationship between linguistic and numerical processing revealed inconsistent results for different levels of cognitive processing (e.g., lexical, semantic) as well as different stimulus materials (e.g., Arabic digits, number words, letters, non-number words). Information of dissociation patterns in aphasic patients was used in order to investigate the dissociability of linguistic and numerical processes. The aim of the present prospective study was a comprehensive, specific, and systematic investigation of relationships between linguistic and numerical processing, considering the impact of asemantic vs. semantic processing and the type of material employed (numbers compared to letters vs. words). A sample of aphasic patients (n = 60) was assessed with a battery of linguistic and numerical tasks directly comparable for their cognitive processing levels (e.g., perceptual, morpho-lexical, semantic). Mean performance differences and frequencies of (complementary) dissociations in individual patients revealed the most prominent numerical advantage for asemantic tasks when comparing the processing of numbers vs. letters, whereas the least numerical advantage was found for semantic tasks when comparing the processing of numbers vs. words. Different patient subgroups showing differential dissociation patterns were further analysed and discussed. A comprehensive model of linguistic and numerical processing should take these findings into account.

Auditory semantic processing in dichotic listening: effects of competing speech, ear of presentation, and sentential bias on N400s to spoken words in context.

PubMed

Carey, Daniel; Mercure, Evelyne; Pizzioli, Fabrizio; Aydelott, Jennifer

2014-12-01

The effects of ear of presentation and competing speech on N400s to spoken words in context were examined in a dichotic sentence priming paradigm. Auditory sentence contexts with a strong or weak semantic bias were presented in isolation to the right or left ear, or with a competing signal presented in the other ear at a SNR of -12 dB. Target words were congruent or incongruent with the sentence meaning. Competing speech attenuated N400s to both congruent and incongruent targets, suggesting that the demand imposed by a competing signal disrupts the engagement of semantic comprehension processes. Bias strength affected N400 amplitudes differentially depending upon ear of presentation: weak contexts presented to the le/RH produced a more negative N400 response to targets than strong contexts, whereas no significant effect of bias strength was observed for sentences presented to the re/LH. The results are consistent with a model of semantic processing in which the RH relies on integrative processing strategies in the interpretation of sentence-level meaning. Copyright © 2014 Elsevier Ltd. All rights reserved.

Computational Cognitive Neuroscience of Early Memory Development

ERIC Educational Resources Information Center

Munakata, Yuko

2004-01-01

Numerous brain areas work in concert to subserve memory, with distinct memory functions relying differentially on distinct brain areas. For example, semantic memory relies heavily on posterior cortical regions, episodic memory on hippocampal regions, and working memory on prefrontal cortical regions. This article reviews relevant findings from…

Changes in Vision: Teachers Engaging in Action Research

ERIC Educational Resources Information Center

Warren, Susan; Doorn, Dan; Green, James

2008-01-01

This investigation explored the effects of action research on teachers in a graduate education program. Mixed methods were utilized, combining a semantic differential study of student attitudes with qualitative analysis of students' perceptions of their experience as action researchers. Results indicate that participants perceived themselves as…

Stereotypes of Middle-Aged and Elderly Professionals.

ERIC Educational Resources Information Center

Decker, Wayne H.

1983-01-01

Used the semantic differential technique to examine attitudes of 115 business students toward middle-aged and older professionals. Results showed older persons were rated lower in all professions and on all attitudinal dimensions (autonomy, effectiveness, personal acceptability). Ratings of professionals were higher than ratings of the average…

Attitudes to Normalisation and Inclusive Education

ERIC Educational Resources Information Center

Sanagi, Tomomi

2016-01-01

The purpose of this paper was to clarify the features of teachers' image on normalisation and inclusive education. The participants of the study were both mainstream teachers and special teachers. One hundred and thirty-eight questionnaires were analysed. (1) Teachers completed the questionnaire of SD (semantic differential) images on…

Cognitive Differences in Pictorial Reasoning between High-Functioning Autism and Asperger's Syndrome

ERIC Educational Resources Information Center

Sahyoun, Cherif P.; Soulieres, Isabelle; Belliveau, John W.; Mottron, Laurent; Mody, Maria

2009-01-01

We investigated linguistic and visuospatial processing during pictorial reasoning in high-functioning autism (HFA), Asperger's syndrome (ASP), and age and IQ-matched typically developing participants (CTRL), using three conditions designed to differentially engage linguistic mediation or visuospatial processing (visuospatial, V; semantic, S;…

Integrating Conceptual Knowledge within and across Representational Modalities

ERIC Educational Resources Information Center

McNorgan, Chris; Reid, Jackie; McRae, Ken

2011-01-01

Research suggests that concepts are distributed across brain regions specialized for processing information from different sensorimotor modalities. Multimodal semantic models fall into one of two broad classes differentiated by the assumed hierarchy of convergence zones over which information is integrated. In shallow models, communication within-…

SU30. Long-Term Memory Deficits in Schizophrenia: Are All Things Equal?

PubMed Central

Rossell, Susan

2017-01-01

Abstract Background: Kraepelin and Bleulernoted that patients with schizophrenia had significant cognitive deficits over a century ago; however, their observations with regard to long-term memory have not born out within empirical studies. They reported that episodic memory was intact but indicated that organization of memories, or semantic memory, was disordered. This study aimed to synthesize a century of research in the 2 long-term memory processes of episodic and semantic memory across the psychosis continuum: chronic patients, first-episode patients, high risk for psychosis cohorts, and persons with high schizotypy. Methods: A systematic review and meta-analysis was completed within the 2 domains of long-term memory across the psychosis continuum. Search terms included long-term memory, episodic, semantic, and derivations of these terms. The data were synthesized independently for episodic and semantic memory. Four independent populations were investigated: chronic patients, first-episode patients, high risk for psychosis cohorts, and persons with high schizotypy. Our approach followed the PRISMA guidelines. Thus, the pooled mean effect sizes are reported for 8 analyses. These effect sizes represent case cohort in comparison to a healthy control cohort. Results: The results were as follows, for episodic memory: chronic patients d = 1.12, first-episode patients d = 1.12, high risk d = 1.14, and high schizotypy d = 0.13. Thus, establishing that there is poor evidence of episodic memory deficits in persons with high schizotypy. For semantic memory, the literature showed a different pattern: chronic patients d = 1.2, first-episode patients d = 1.08, high risk d = 1.16, and high schizotypy d = 0.95. Thus, a consistent degree of semantic memory deficits across the continuum. Conclusion: The literature suggests a dissociated pattern of long-term memory deficits; whereby semantic memory abnormalities are more likely to be considered endophenotypes or cognitive markers for schizophrenia than episodic memory deficits. Differential patterns of semantic memory organization are argued to be present prior to the onset of the disorder. There is additional evidence to suggest that idiosyncratic storage of semantic material underlies the development of the usual beliefs and speech patterns present in the forms of delusions and formal thought disorder. Consequently, semantic memory might be a useful target for cognitive remediation.

An Attempt at Assessing Preferences for Natural Landscapes

ERIC Educational Resources Information Center

Calvin, James S.; And Others

1972-01-01

Investigation of ways in which man makes a psychological assessment of his environment. Concerned with variables in the environment itself, fifteen photographs of natural landscape scenes were rated on each of twenty-one semantic differential scales by college students. Two major dimensions emerged: natural scenic beauty and a natural force…

The Application of Operations Research Techniques to the Evaluation of Military Management Information Systems.

DTIC Science & Technology

systems such as management information systems . To provide a methodology yielding quantitative results which may assist a commander and his staff in...this analysis, it is proposed that management information systems be evaluated as a whole by a technique defined as the semantic differential. Each

Measuring perception of elements in outdoor environments

Treesearch

George H. Moeller; Robert MacLachlan; Douglas A. Morrison

1974-01-01

The meanings of 10 concepts that describe elements of natural outdoor environments were measured with the semantic differential technique. Each concept was evaluated on three factors of meaning - evaluation, potency, and activity. Sixty recreationists were surveyed from each of three user groups - campers, picnickers, and wilderness hikers. Similarities and differences...

Brain Responses Differ to Faces of Mothers and Fathers

ERIC Educational Resources Information Center

Arsalidou, Marie; Barbeau, Emmanuel J.; Bayless, Sarah J.; Taylor, Margot J.

2010-01-01

We encounter many faces each day but relatively few are personally familiar. Once faces are familiar, they evoke semantic and social information known about the person. Neuroimaging studies demonstrate differential brain activity to familiar and non-familiar faces; however, brain responses related to personally familiar faces have been more rarely…

A Comparison of Colour and Black and White T. V.

ERIC Educational Resources Information Center

Reich, Carol; Meisner, Alan

The relative educational effectiveness of color vs. black and white television has not been exhaustively explored. While previous studies have concentrated on the factual retention of subject matter--bypassing the subjective attitudes--this study was designed to thoroughly analyze both areas. Using Osgood's Semantic Differential and the Liking…

Listeners' Perceptions of Speech and Language Disorders

ERIC Educational Resources Information Center

Allard, Emily R.; Williams, Dale F.

2008-01-01

Using semantic differential scales with nine trait pairs, 445 adults rated five audio-taped speech samples, one depicting an individual without a disorder and four portraying communication disorders. Statistical analyses indicated that the no disorder sample was rated higher with respect to the trait of employability than were the articulation,…

Temporal Persistence of Attitudes Induced Through Required Training

ERIC Educational Resources Information Center

Tansik, David A.; Driskill, John D.

1977-01-01

A posttest-only control group design procedure was used with a semantic differential questionnaire to examine the persistence of changes in racial attitudes induced via a required training course for supervisors at a large military installation. There was an immediate, small, positive change which decayed, and a short "sleeper effect". (Author)

The Connotative Dimensions of Selected Display Typefaces.

ERIC Educational Resources Information Center

Benton, Camille L.

The semantic differential ratings of ten typefaces given by a group of 24 subjects were factor analyzed to discover what connotative meanings laypeople applied to typefaces and how these meanings compared with those of professional typographers. The typefaces, five from general categories and five from novelty categories of display typefaces, were…

Experiential Learning about the Elderly: The Geriatric Medication Game.

ERIC Educational Resources Information Center

Oliver, Carol H.; And Others

1995-01-01

An active learning simulation game designed to increase pharmacy students' awareness of the physical, psychological, and financial difficulties of the ambulatory elderly in handling their medication is described. Questionnaires before and after the game, including a semantic differential tool, indicate that the program is successful in increasing…

Semantic features of 'stepped' versus 'continuous' contours in German intonation.

PubMed

Dombrowski, Ernst

2013-01-01

This study analyses the meaning spaces of German pitch contours using two modes of melodic movement: continuous or in steps of sustained pitch. Both the continuous and stepped movements are represented by a set of five basic patterns, the latter being derived from the former. Thirty-six German native speakers judged the pattern sets on a 12-scale semantic differential. The semantic profiles confirm that stepped contours can be conceived of as stylized intonation, in a formal as well as in a functional sense. On the one hand, continuous (non-stylized) and stepped (stylized) contours are assigned different overall meanings (especially on the scales astonished - commonplace and interested - not interested). On the other hand, listeners organize the two contour sets in a similar fashion, which speaks in favour of parallel pattern inventories of continuous and stepped movement, respectively. However, the meaning space of the stylized patterns is affected by formal restrictions, for instance in the step transformation of continuous rises. © 2014 S. Karger AG, Basel.

What is said or how it is said makes a difference: role of the right fronto-parietal operculum in emotional prosody as revealed by repetitive TMS.

PubMed

van Rijn, Sophie; Aleman, André; van Diessen, Eric; Berckmoes, Celine; Vingerhoets, Guy; Kahn, René S

2005-06-01

Emotional signals in spoken language can be conveyed by semantic as well as prosodic cues. We investigated the role of the fronto-parietal operculum, a somatosensory area where the lips, tongue and jaw are represented, in the right hemisphere to detection of emotion in prosody vs. semantics. A total of 14 healthy volunteers participated in the present experiment, which involved transcranial magnetic stimulation (TMS) in combination with frameless stereotaxy. As predicted, compared with sham stimulation, TMS over the right fronto-parietal operculum differentially affected the reaction times for detection of emotional prosody vs. emotional semantics, showing that there is a dissociation at a neuroanatomical level. Detection of withdrawal emotions (fear and sadness) in prosody was delayed significantly by TMS. No effects of TMS were observed for approach emotions (happiness and anger). We propose that the right fronto-parietal operculum is not globally involved in emotion evaluation, but sensitive to specific forms of emotional discrimination and emotion types.

Autobiographical narratives relate to Alzheimer's disease biomarkers in older adults.

PubMed

Buckley, Rachel F; Saling, Michael M; Irish, Muireann; Ames, David; Rowe, Christopher C; Villemagne, Victor L; Lautenschlager, Nicola T; Maruff, Paul; Macaulay, S Lance; Martins, Ralph N; Szoeke, Cassandra; Masters, Colin L; Rainey-Smith, Stephanie R; Rembach, Alan; Savage, Greg; Ellis, Kathryn A

2014-10-01

Autobiographical memory (ABM), personal semantic memory (PSM), and autonoetic consciousness are affected in individuals with mild cognitive impairment (MCI) but their relationship with Alzheimer's disease (AD) biomarkers are unclear. Forty-five participants (healthy controls (HC) = 31, MCI = 14) completed the Episodic ABM Interview and a battery of memory tests. Thirty-one (HC = 22, MCI = 9) underwent β-amyloid positron emission tomography (PET) and magnetic resonance (MR) imaging. Fourteen participants (HC = 9, MCI = 5) underwent one imaging modality. Unlike PSM, ABM differentiated between diagnostic categories but did not relate to AD biomarkers. Personal semantic memory was related to neocortical β-amyloid burden after adjusting for age and apolipoprotein E (APOE) ɛ4. Autonoetic consciousness was not associated with AD biomarkers, and was not impaired in MCI. Autobiographical memory was impaired in MCI participants but was not related to neocortical amyloid burden, suggesting that personal memory systems are impacted by differing disease mechanisms, rather than being uniformly underpinned by β-amyloid. Episodic and semantic ABM impairment represent an important AD prodrome.

Emotional connotations of words related to authority and community.

PubMed

Schauenburg, Gesche; Ambrasat, Jens; Schröder, Tobias; von Scheve, Christian; Conrad, Markus

2015-09-01

We present a database of 858 German words from the semantic fields of authority and community, which represent core dimensions of human sociality. The words were selected on the basis of co-occurrence profiles of representative keywords for these semantic fields. All words were rated along five dimensions, each measured by a bipolar semantic-differential scale: Besides the classic dimensions of affective meaning (valence, arousal, and potency), we collected ratings of authority and community with newly developed scales. The results from cluster, correlational, and multiple regression analyses on the rating data suggest a robust negativity bias for authority valuation among German raters recruited via university mailing lists, whereas community ratings appear to be rather unrelated to the well-established affective dimensions. Furthermore, our data involve a strong overall negative correlation-rather than the classical U-shaped distribution-between valence and arousal for socially relevant concepts. Our database provides a valuable resource for research questions at the intersection of cognitive neuroscience and social psychology. It can be downloaded as supplemental materials with this article.

Functional Fixedness in Creative Thinking Tasks Depends on Stimulus Modality.

PubMed

Chrysikou, Evangelia G; Motyka, Katharine; Nigro, Cristina; Yang, Song-I; Thompson-Schill, Sharon L

2016-11-01

Pictorial examples during creative thinking tasks can lead participants to fixate on these examples and reproduce their elements even when yielding suboptimal creative products. Semantic memory research may illuminate the cognitive processes underlying this effect. Here, we examined whether pictures and words differentially influence access to semantic knowledge for object concepts depending on whether the task is close- or open-ended. Participants viewed either names or pictures of everyday objects, or a combination of the two, and generated common, secondary, or ad hoc uses for them. Stimulus modality effects were assessed quantitatively through reaction times and qualitatively through a novel coding system, which classifies creative output on a continuum from top-down-driven to bottom-up-driven responses. Both analyses revealed differences across tasks. Importantly, for ad hoc uses, participants exposed to pictures generated more top-down-driven responses than those exposed to object names. These findings have implications for accounts of functional fixedness in creative thinking, as well as theories of semantic memory for object concepts.

Functional Fixedness in Creative Thinking Tasks Depends on Stimulus Modality

PubMed Central

Chrysikou, Evangelia G.; Motyka, Katharine; Nigro, Cristina; Yang, Song-I; Thompson-Schill, Sharon L.

2015-01-01

Pictorial examples during creative thinking tasks can lead participants to fixate on these examples and reproduce their elements even when yielding suboptimal creative products. Semantic memory research may illuminate the cognitive processes underlying this effect. Here, we examined whether pictures and words differentially influence access to semantic knowledge for object concepts depending on whether the task is close- or open-ended. Participants viewed either names or pictures of everyday objects, or a combination of the two, and generated common, secondary, or ad hoc uses for them. Stimulus modality effects were assessed quantitatively through reaction times and qualitatively through a novel coding system, which classifies creative output on a continuum from top-down-driven to bottom-up-driven responses. Both analyses revealed differences across tasks. Importantly, for ad hoc uses, participants exposed to pictures generated more top-down-driven responses than those exposed to object names. These findings have implications for accounts of functional fixedness in creative thinking, as well as theories of semantic memory for object concepts. PMID:28344724

Neural division of labor in reading is constrained by culture: A training study of reading Chinese characters

PubMed Central

Zhao, Jingjing; Wang, Xiaoyi; Frost, Stephen J.; Sun, Wan; Fang, Shin-Yi; Mencl, W. Einar; Pugh, Kenneth R.; Shu, Hua; Rueckl, Jay G.

2014-01-01

Word reading in alphabetic language involves a cortical system with multiple components whose division of labor depends on the transparency of the writing system. To gain insight about the division of labor between phonology and semantics subserving word reading in Chinese, a deep non-alphabetic writing system, fMRI was used to investigate the effects of phonological and semantic training on the cortical circuitry for oral naming of Chinese characters. In a training study, we examined whether a training task that differentially focused readers' attention on the phonological or semantic properties of a Chinese character changes the patterns of cortical activation that was evoked by that character in a subsequent naming task. Our imaging results corroborate that the cortical regions underlying reading in Chinese largely overlaps the left-hemisphere reading system responsible for reading in alphabetic languages, with some cortical regions in the left-hemisphere uniquely recruited for reading in Chinese. However, in contrast to findings from studies of English word naming, we observed considerable overlap in the neural activation patterns associated with phonological and semantic training on naming Chinese characters, which we suggest may reflect a balanced neural division of labor between phonology and semantics in Chinese character reading. The equitable division of labor for Chinese reading might be driven by the special statistical structure of the writing system, which includes equally systematic mappings in the correspondences between written forms and their pronunciations and meanings. PMID:24607883

Apathy, not depressive symptoms, as a predictor of semantic and phonemic fluency task performance in stroke and transient ischemic attack.

PubMed

Fishman, Keera N; Ashbaugh, Andrea R; Lanctôt, Krista L; Cayley, Megan L; Herrmann, Nathan; Murray, Brian J; Sicard, Michelle; Lien, Karen; Sahlas, Demetrios J; Swartz, Richard H

2018-06-01

This study examined the relationship between apathy and cognition in patients with cerebrovascular disease. Apathy may result from damage to frontal subcortical circuits causing dysexecutive syndromes, but apathy is also related to depression. We assessed the ability of apathy to predict phonemic fluency and semantic fluency performance after controlling for depressive symptoms in 282 individuals with stroke and/or transient ischemic attack. Participants (N = 282) completed the Phonemic Fluency Test, Semantic Fluency Test, Center for Epidemiologic Studies Depression Scale, and Apathy Evaluation Scale. A cross-sectional correlational design was utilized. Using hierarchical linear regressions, apathy scores significantly predicted semantic fluency performance (β = -.159, p = .020), but not phonemic fluency performance (β = -.112, p = .129) after scaling scores by age and years of education and controlling for depressive symptoms. Depressive symptoms entered into the first step of both hierarchical linear regressions did not predict semantic fluency (β = -.035, p = .554) or phonemic fluency (β = -.081, p = .173). Apathy and depressive symptoms were moderately correlated, r(280) = .58, p < .001. The results of this study are consistent with research supporting a differentiation between phonemic and semantic fluency tasks, whereby phonemic fluency tasks primarily involve frontal regions, and semantic fluency tasks involve recruitment of more extended networks. The results also highlight a distinction between apathy and depressive symptoms and suggest that apathy may be a more reliable predictor of cognitive deficits than measures of mood in individuals with cerebrovascular disease. Apathy may also be more related to cognition due to overlapping motivational and cognitive frontal subcortical circuitry. Future research should explore whether treatments for apathy could be a novel target for improving cognitive outcomes after stroke.

Lung cancer signature biomarkers: tissue specific semantic similarity based clustering of digital differential display (DDD) data.

PubMed

Srivastava, Mousami; Khurana, Pankaj; Sugadev, Ragumani

2012-11-02

The tissue-specific Unigene Sets derived from more than one million expressed sequence tags (ESTs) in the NCBI, GenBank database offers a platform for identifying significantly and differentially expressed tissue-specific genes by in-silico methods. Digital differential display (DDD) rapidly creates transcription profiles based on EST comparisons and numerically calculates, as a fraction of the pool of ESTs, the relative sequence abundance of known and novel genes. However, the process of identifying the most likely tissue for a specific disease in which to search for candidate genes from the pool of differentially expressed genes remains difficult. Therefore, we have used 'Gene Ontology semantic similarity score' to measure the GO similarity between gene products of lung tissue-specific candidate genes from control (normal) and disease (cancer) sets. This semantic similarity score matrix based on hierarchical clustering represents in the form of a dendrogram. The dendrogram cluster stability was assessed by multiple bootstrapping. Multiple bootstrapping also computes a p-value for each cluster and corrects the bias of the bootstrap probability. Subsequent hierarchical clustering by the multiple bootstrapping method (α = 0.95) identified seven clusters. The comparative, as well as subtractive, approach revealed a set of 38 biomarkers comprising four distinct lung cancer signature biomarker clusters (panel 1-4). Further gene enrichment analysis of the four panels revealed that each panel represents a set of lung cancer linked metastasis diagnostic biomarkers (panel 1), chemotherapy/drug resistance biomarkers (panel 2), hypoxia regulated biomarkers (panel 3) and lung extra cellular matrix biomarkers (panel 4). Expression analysis reveals that hypoxia induced lung cancer related biomarkers (panel 3), HIF and its modulating proteins (TGM2, CSNK1A1, CTNNA1, NAMPT/Visfatin, TNFRSF1A, ETS1, SRC-1, FN1, APLP2, DMBT1/SAG, AIB1 and AZIN1) are significantly down regulated. All down regulated genes in this panel were highly up regulated in most other types of cancers. These panels of proteins may represent signature biomarkers for lung cancer and will aid in lung cancer diagnosis and disease monitoring as well as in the prediction of responses to therapeutics.

Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imaging.

PubMed

Kiehl, Kent A; Smith, Andra M; Mendrek, Adrianna; Forster, Bruce B; Hare, Robert D; Liddle, Peter F

2004-04-30

We tested the hypothesis that psychopathy is associated with abnormalities in semantic processing of linguistic information. Functional magnetic resonance imaging (fMRI) was used to elucidate and characterize the neural architecture underlying lexico-semantic processes in criminal psychopathic individuals and in a group of matched control participants. Participants performed a lexical decision task in which blocks of linguistic stimuli alternated with a resting baseline condition. In each lexical decision block, the stimuli were either concrete words and pseudowords or abstract words and pseudowords. Consistent with our hypothesis, psychopathic individuals, relative to controls, showed poorer behavioral performance for processing abstract words. Analysis of the fMRI data for both groups indicated that processing of word stimuli, compared with the resting baseline condition, was associated with neural activation in bilateral fusiform gyrus, anterior cingulate, left middle temporal gyrus, right posterior superior temporal gyrus, and left and right inferior frontal gyrus. Analyses confirmed our prediction that psychopathic individuals would fail to show the appropriate neural differentiation between abstract and concrete stimuli in the right anterior temporal gyrus and surrounding cortex. The results are consistent with other studies of semantic processing in psychopathy and support the theory that psychopathy is associated with right hemisphere abnormalities for processing conceptually abstract material.

Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imaging.

PubMed

Kiehl, Kent A; Smith, Andra M; Mendrek, Adrianna; Forster, Bruce B; Hare, Robert D; Liddle, Peter F

2004-01-15

We tested the hypothesis that psychopathy is associated with abnormalities in semantic processing of linguistic information. Functional magnetic resonance imaging (fMRI) was used to elucidate and characterize the neural architecture underlying lexico-semantic processes in criminal psychopathic individuals and in a group of matched control participants. Participants performed a lexical decision task in which blocks of linguistic stimuli alternated with a resting baseline condition. In each lexical decision block, the stimuli were either concrete words and pseudowords or abstract words and pseudowords. Consistent with our hypothesis, psychopathic individuals, relative to controls, showed poorer behavioral performance for processing abstract words. Analysis of the fMRI data for both groups indicated that processing of word stimuli, compared with the resting baseline condition, was associated with neural activation in bilateral fusiform gyrus, anterior cingulate, left middle temporal gyrus, right posterior superior temporal gyrus, and left and right inferior frontal gyrus. Analyses confirmed our prediction that psychopathic individuals would fail to show the appropriate neural differentiation between abstract and concrete stimuli in the right anterior temporal gyrus and surrounding cortex. The results are consistent with other studies of semantic processing in psychopathy and support the theory that psychopathy is associated with right hemisphere abnormalities for processing conceptually abstract material.

Abnormal dynamics of language in schizophrenia.

PubMed

Stephane, Massoud; Kuskowski, Michael; Gundel, Jeanette

2014-05-30

Language could be conceptualized as a dynamic system that includes multiple interactive levels (sub-lexical, lexical, sentence, and discourse) and components (phonology, semantics, and syntax). In schizophrenia, abnormalities are observed at all language elements (levels and components) but the dynamic between these elements remains unclear. We hypothesize that the dynamics between language elements in schizophrenia is abnormal and explore how this dynamic is altered. We, first, investigated language elements with comparable procedures in patients and healthy controls. Second, using measures of reaction time, we performed multiple linear regression analyses to evaluate the inter-relationships among language elements and the effect of group on these relationships. Patients significantly differed from controls with respect to sub-lexical/lexical, lexical/sentence, and sentence/discourse regression coefficients. The intercepts of the regression slopes increased in the same order above (from lower to higher levels) in patients but not in controls. Regression coefficients between syntax and both sentence level and discourse level semantics did not differentiate patients from controls. This study indicates that the dynamics between language elements is abnormal in schizophrenia. In patients, top-down flow of linguistic information might be reduced, and the relationship between phonology and semantics but not between syntax and semantics appears to be altered. Published by Elsevier Ireland Ltd.

Interactions between mood and the structure of semantic memory: event-related potentials evidence

PubMed Central

Pinheiro, Ana P.; del Re, Elisabetta; Nestor, Paul G; McCarley, Robert W.; Gonçalves, Óscar F.

2013-01-01

Recent evidence suggests that affect acts as modulator of cognitive processes and in particular that induced mood has an effect on the way semantic memory is used on-line. We used event-related potentials (ERPs) to examine affective modulation of semantic information processing under three different moods: neutral, positive and negative. Fifteen subjects read 324 pairs of sentences, after mood induction procedure with 30 pictures of neutral, 30 pictures of positive and 30 pictures of neutral valence: 108 sentences were read in each mood induction condition. Sentences ended with three word types: expected words, within-category violations, and between-category violations. N400 amplitude was measured to the three word types under each mood induction condition. Under neutral mood, a congruency (more negative N400 amplitude for unexpected relative to expected endings) and a category effect (more negative N400 amplitude for between- than to within-category violations) were observed. Also, results showed differences in N400 amplitude for both within- and between-category violations as a function of mood: while positive mood tended to facilitate the integration of unexpected but related items, negative mood made their integration as difficult as unexpected and unrelated items. These findings suggest the differential impact of mood on access to long-term semantic memory during sentence comprehension. PMID:22434931

Interactions between mood and the structure of semantic memory: event-related potentials evidence.

PubMed

Pinheiro, Ana P; del Re, Elisabetta; Nestor, Paul G; McCarley, Robert W; Gonçalves, Óscar F; Niznikiewicz, Margaret

2013-06-01

Recent evidence suggests that affect acts as modulator of cognitive processes and in particular that induced mood has an effect on the way semantic memory is used on-line. We used event-related potentials (ERPs) to examine affective modulation of semantic information processing under three different moods: neutral, positive and negative. Fifteen subjects read 324 pairs of sentences, after mood induction procedure with 30 pictures of neutral, 30 pictures of positive and 30 pictures of neutral valence: 108 sentences were read in each mood induction condition. Sentences ended with three word types: expected words, within-category violations, and between-category violations. N400 amplitude was measured to the three word types under each mood induction condition. Under neutral mood, a congruency (more negative N400 amplitude for unexpected relative to expected endings) and a category effect (more negative N400 amplitude for between- than to within-category violations) were observed. Also, results showed differences in N400 amplitude for both within- and between-category violations as a function of mood: while positive mood tended to facilitate the integration of unexpected but related items, negative mood made their integration as difficult as unexpected and unrelated items. These findings suggest the differential impact of mood on access to long-term semantic memory during sentence comprehension.

The Topology of a Discussion: The #Occupy Case.

PubMed

Gargiulo, Floriana; Bindi, Jacopo; Apolloni, Andrea

2015-01-01

We analyse a large sample of the Twitter activity that developed around the social movement 'Occupy Wall Street', to study the complex interactions between the human communication activity and the semantic content of a debate. We use a network approach based on the analysis of the bipartite graph @Users-#Hashtags and of its projections: the 'semantic network', whose nodes are hashtags, and the 'users interest network', whose nodes are users. In the first instance, we find out that discussion topics (#hashtags) present a high structural heterogeneity, with a relevant role played by the semantic hubs that are responsible to guarantee the continuity of the debate. In the users' case, the self-organisation process of users' activity, leads to the emergence of two classes of communicators: the 'professionals' and the 'amateurs'. Both the networks present a strong community structure, based on the differentiation of the semantic topics, and a high level of structural robustness when certain sets of topics are censored and/or accounts are removed. By analysing the characteristics of the dynamical networks we can distinguish three phases of the discussion about the movement. Each phase corresponds to a specific moment of the movement: from declaration of intent, organisation and development and the final phase of political reactions. Each phase is characterised by the presence of prototypical #hashtags in the discussion.

Classification deficits in Alzheimer's disease with special reference to living and nonliving things.

PubMed

Montanes, P; Goldblum, M C; Boller, F

1996-08-01

The present study was conducted to assess the hypothesis that visual similarity between exemplars within a semantic category may affect differentially the recognition process of living and nonliving things, according to task demands, in patients with semantic memory disorders. Thirty-nine Alzheimer's patients and 39 normal elderly subjects were presented with a task in which they had to classify pictures and words, depicting either living or nonliving things, at two levels of classification: subordinate (e.g., mammals versus birds or tools versus vehicles) and attribute (e.g., wild versus domestic animals or fast versus slow vehicles). Contrary to previous results (Montañes, Goldblum, & Boller, 1995) in a naming task, but as expected, living things were better classified than nonliving ones by both controls and patients. As expected, classifications at the subordinate level also gave rise to better performance than classifications at the attribute level. Although (and somewhat unexpectedly) no advantage of picture over word classification emerged, some effects consistent with the hypothesis that visual similarity affects picture classification emerged, in particular within a subgroup of patients with predominant verbal deficits and the most severe semantic memory disorders. This subgroup obtained a better score on classification of pictures than of words depicting living items (that share many visual features) when classification is at the subordinate level (for which visual similarity is a reliable clue to classification), but met with major difficulties when classifying those pictures at the attribute level (for which shared visual features are not reliable clues to classification). These results emphasize the fact that some "normal" effects specific to items in living and nonliving categories have to be considered among the factors causing selective category-specific deficits in patients, as well as their relevance in achieving tasks which require either differentiation between competing exemplars in the same semantic category (naming) or detection of resemblance between those exemplars (categorization).

Lexical learning in mild aphasia: gesture benefit depends on patholinguistic profile and lesion pattern.

PubMed

Kroenke, Klaus-Martin; Kraft, Indra; Regenbrecht, Frank; Obrig, Hellmuth

2013-01-01

Gestures accompany speech and enrich human communication. When aphasia interferes with verbal abilities, gestures become even more relevant, compensating for and/or facilitating verbal communication. However, small-scale clinical studies yielded diverging results with regard to a therapeutic gesture benefit for lexical retrieval. Based on recent functional neuroimaging results, delineating a speech-gesture integration network for lexical learning in healthy adults, we hypothesized that the commonly observed variability may stem from differential patholinguistic profiles in turn depending on lesion pattern. Therefore we used a controlled novel word learning paradigm to probe the impact of gestures on lexical learning, in the lesioned language network. Fourteen patients with chronic left hemispheric lesions and mild residual aphasia learned 30 novel words for manipulable objects over four days. Half of the words were trained with gestures while the other half were trained purely verbally. For the gesture condition, rootwords were visually presented (e.g., Klavier, [piano]), followed by videos of the corresponding gestures and the auditory presentation of the novel words (e.g., /krulo/). Participants had to repeat pseudowords and simultaneously reproduce gestures. In the verbal condition no gesture-video was shown and participants only repeated pseudowords orally. Correlational analyses confirmed that gesture benefit depends on the patholinguistic profile: lesser lexico-semantic impairment correlated with better gesture-enhanced learning. Conversely largely preserved segmental-phonological capabilities correlated with better purely verbal learning. Moreover, structural MRI-analysis disclosed differential lesion patterns, most interestingly suggesting that integrity of the left anterior temporal pole predicted gesture benefit. Thus largely preserved semantic capabilities and relative integrity of a semantic integration network are prerequisites for successful use of the multimodal learning strategy, in which gestures may cause a deeper semantic rooting of the novel word-form. The results tap into theoretical accounts of gestures in lexical learning and suggest an explanation for the diverging effect in therapeutical studies advocating gestures in aphasia rehabilitation. Copyright © 2013 Elsevier Ltd. All rights reserved.

A Semantic Differential Evaluation of Attitudinal Outcomes of Introductory Physical Science.

ERIC Educational Resources Information Center

Hecht, Alfred Roland

This study was designed to assess the attitudinal outcomes of Introductory Physical Science (IPS) curriculum materials used in schools. Random samples of 240 students receiving IPS instruction and 240 non-science students were assigned to separate Solomon four-group designs with non-equivalent control groups. Random samples of 60 traditional…

Semantic Differential Comparisons of Attributions and Dimensions among Seven Nations.

ERIC Educational Resources Information Center

Chandler, Theodore A.; Spies, Carl J.

The classifications of 11 attributions according to dimensions of locus, stability, controllability, predictability, and globality by participants in 7 countries (China, France, Germany, Hong Kong, Israel, Spain, and the United States) were compared in a cross-cultural study. The attributions were: (1) bias; (2) help; (3) luck; (4) ability; (5)…

The Development and Validation of a Behaviorally Defined Interest Instrument for Science.

ERIC Educational Resources Information Center

Butzow, John W., Jr.

A semantic differential (SD) instrument, modified by replacing words or noun phrases with phrases describing a behavior, was administered to male freshmen students. Six items discriminated between two groups, 97 science majors and 161 non-science majors, on three axes, labelled as evaluation, potency, and activity. To test whether the instrument…

Adolescents' Perceptions of Foreign-Made Products: Implications for Advertising Strategy.

ERIC Educational Resources Information Center

Reid, Leonard N.; Vanden Bergh, Bruce G.

A five-point, seven-item semantic differential scale was used to collect data from 130 high school students about their perceptions of foreign-made products and the relation of national stereotypes to product stereotypes. To assure consistency, the same product classes (all products, automobiles, cameras, and mechanical toys) and foreign countries…

Standardization of Selected Semantic Differential Scales with Secondary School Children.

ERIC Educational Resources Information Center

Evans, G. T.

A basic assumption of this study is that the meaning continuum registered by an adjective pair remains relatively constant over a large universe of concepts and over subjects within a relatively homogeneous population. An attempt was made to validate this assumption by showing the invariance of the factor structure across different types of…

Can Racial Attitudes Be Changed? Synopis.

ERIC Educational Resources Information Center

Ijaz, M. Ahmed

The attitudes of white Canadian fifth and sixth graders toward blacks and East Indians were examined by means of a semantic differential measure, a social distance scale, and a contact questionnaire. No significant differences in attitudes were found between students in schools with a high and low proportion of black and East Indian students.…

High School Students' Affective Reaction to English Speaking Activities

ERIC Educational Resources Information Center

Jorquera Torres, Oliver Camilo; Mendoza Zapata, Jhon Eliot; Díaz Larenas, Claudio Heraldo

2017-01-01

This study aims to measure fifty-two high school students' affective reactions after doing individual and pair-based speaking activities then completing a semantic differential scale of nine bipolar adjectives. Results do not show significant statistical differences between the two types of activities or the schools involved in this study, but…

Student Attitudes toward Nuclear Power Plants: A Classroom Experiment in the Field of Environmental Psychology.

ERIC Educational Resources Information Center

Spada, Hans; And Others

1977-01-01

As part of a senior high school physics unit on nuclear power, changes in student attitudes toward nuclear power plants and problems of energy supply were analyzed. Tests included a situational test, semantic differentials, knowledge or achievement, and a final questionnaire. The results are discussed. (CTM)

The Effects of Priming on Children's Attitudes toward Older Individuals

ERIC Educational Resources Information Center

Hoe, Sony; Davidson, Denise

2002-01-01

The purpose of the present research was to examine younger (7-years-old) and older (10-years-old) children's attitudes toward older individuals following one type of five primes: positive prime, negative prime, elderly prime, grandparent prime, or neutral prime. Overall, children's attitudes on three tests--Apperception, Semantic Differential, and…

The Parochial Education of Menominee Indian Children: A Study of One School.

ERIC Educational Resources Information Center

Sherarts, I. Karon; And Others

During May 1969 fieldwork for the National Study of American Indian Education was conducted at a Catholic school in Menominee County, Wisconsin. Data were collected by draw-a-man, student questionnaires, semantic differential, achievement test data, and interviews for 78 Menominee Indian students (55% female; 44% male). This report discussed…

Exploring the Utility of a School-Age Narrative Microstructure Index: Proportion of Restricted Utterances

ERIC Educational Resources Information Center

Jerger, Sara; Thorne, John C.

2016-01-01

Purpose: This research attempted to replicate Hoffman's 2009 finding that the proportion of narrative utterances with semantic or syntactic errors (i.e., = 14% "restricted utterances") can differentiate school-age children with typical development from those with language impairment with a sensitivity of 83% and specificity of 88%.…

There Is Something about Grammatical Category in Chinese Visual Word Recognition

ERIC Educational Resources Information Center

Kwong, Oi Yee

2016-01-01

The differential processing of nouns and verbs has been attributed to a combination of morphological, syntactic and semantic factors which are often intertwined with other general lexical properties. This study tested the noun-verb difference with Chinese disyllabic words controlled on various lexical parameters. As Chinese words are free from…

Changes in Perception of Selected Concepts That Accompany Differing Leadership Treatments.

ERIC Educational Resources Information Center

Callan, Laurence Brian

A study was made of effects of two different leadership treatments on perception of nonverbal stimuli relating to concepts of leaders, authority, and cohesion as measured by changes in the Semantic Differential Scale. Subjects (28 Yaqui Indian and Mexican-American members of the Neighborhood Youth Corps) were randomly assigned to an autocratic…

Words Matter: A Semantic Differential Study of Recreation, Leisure, Play, Activity, and Sport

ERIC Educational Resources Information Center

Schlag, Paul A.; Yoder, Daniel G.; Sheng, Zhaohui

2015-01-01

Beyond the standard definitions found in the dictionary, words commonly used in the recreation field have subtle, yet powerful connotations of which senders and receivers of information may not be consciously aware. These words elicit different conscious and subconscious reactions that likely bear significant consequences for recreation agencies…

The Effects of Two Types of Exposure on Attitudes toward Aspects of Juvenile Delinquency.

ERIC Educational Resources Information Center

LeUnes, Arnold; And Others

1996-01-01

Tracks the attitude changes of a group of abnormal psychology students following a tour of a juvenile correctional facility and a presentation by four of the inmates. A 25-item semantic differential scale revealed a noticeable improvement in the students' attitudes towards juvenile delinquents after the visit. (MJP)

76 FR 77203 - Notice of Intent To Seek Approval To Collect Information

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... Web pages created and maintained by component organizations of the NAL. On average, 2 million people... interest collections have established a Web presence with a home page and links to sub-pages that provide... Semantic Differential Scale or multiple choice questions, and no more than 4 open-ended response questions...

82 FR 58411 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2017-12-12

... be in the form of a web page for a fictitious drug targeted toward consumers who have chronic pain or... prescription drug information in multiple formats--including print, television, web, and other modes--would be... framed items. Moreover, the slider questions referenced by the commenter are semantic differentials...

The Differential Role of Phonological and Distributional Cues in Grammatical Categorisation

ERIC Educational Resources Information Center

Monaghan, P.; Chater, N.; Christiansen, M.H.

2005-01-01

Recognising the grammatical categories of words is a necessary skill for the acquisition of syntax and for on-line sentence processing. The syntactic and semantic context of the word contribute as cues for grammatical category assignment, but phonological cues, too, have been implicated as important sources of information. The value of…

Marathon Group Counseling with Illicit Drug Abusers: Effects on Self-Perceptions.

ERIC Educational Resources Information Center

Page, Richard C.; And Others

1987-01-01

Compared effects, for illicit drug abusers, of five 16-hour unstructured marathon groups, and five matched, randomly selected control groups. Used semantic differential consisting of the specific adjective pairs and the evaluative scale of the concept My Real Self. Marathon group members rated some adjective pairs differently and rated the…

Blond is Beautiful: Status and Preference by Hair Color.

ERIC Educational Resources Information Center

Clayson, Dennis E.; Maughan, Micol R.

Three studies were conducted to investigate stereotypes of men of various hair colors by middle-class Anglo college students. Study 1 found an increase of perceived blondness with status, while lack of status was associated with red hair. Study 2, using semantic differentials (after Osgood), found blonde males to be significantly more beautiful,…

Using Life Histories to Individualize Nursing Home Staff Attitudes toward Residents.

ERIC Educational Resources Information Center

Pietrukowicz, Mary E.; Johnson, Mitzi M. S.

1991-01-01

Nurse's aides (n=43) at two institutions answered questions about their experience and knowledge of aging and rated nursing home residents on a semantic differential (attitude) scale. Results indicated including a brief life history in a routine medical chart caused aides to perceive residents in a more positive manner. (Author/ABL)

Differential processing of thematic and categorical conceptual relations in spoken word production.

PubMed

de Zubicaray, Greig I; Hansen, Samuel; McMahon, Katie L

2013-02-01

Studies of semantic context effects in spoken word production have typically distinguished between categorical (or taxonomic) and associative relations. However, associates tend to confound semantic features or morphological representations, such as whole-part relations and compounds (e.g., BOAT-anchor, BEE-hive). Using a picture-word interference paradigm and functional magnetic resonance imaging (fMRI), we manipulated categorical (COW-rat) and thematic (COW-pasture) TARGET-distractor relations in a balanced design, finding interference and facilitation effects on naming latencies, respectively, as well as differential patterns of brain activation compared with an unrelated distractor condition. While both types of distractor relation activated the middle portion of the left middle temporal gyrus (MTG) consistent with retrieval of conceptual or lexical representations, categorical relations involved additional activation of posterior left MTG, consistent with retrieval of a lexical cohort. Thematic relations involved additional activation of the left angular gyrus. These results converge with recent lesion evidence implicating the left inferior parietal lobe in processing thematic relations and may indicate a potential role for this region during spoken word production. 2013 APA, all rights reserved

Cross-cultural examination of the semantic dimensions of body postures.

PubMed

Kudoh, T; Matsumoto, D

1985-06-01

In two studies, we examined the cross-cultural validity of the dimensional structures with which postures are judged. In Study 1, 686 Japanese subjects rated 40 posture expressions on sixteen 5-point semantic differential scale items. Subjects inferred an encoder's attitude towards oneself (i.e., the decoding subject) in hypothetical dyadic situations. A principal-component factor analysis yielded evidence for three independent dimensions resembling those proposed by Schlosberg (1954), Osgood (1966), and Williams and Sundene (1965). These three factors were named self-fulfillment, interpersonal positiveness, and interpersonal consciousness. In Study 2, 336 Japanese students again rated the 40 posture expressions on the sixteen 5-point differential items, but an attempt was made to control for the status of the hypothetical encoder. The results of this study essentially replicated those of Study 1. One interesting finding was that although we found the same factors as those found in studies conducted in the West, the order of the factors in our studies was the reverse of the order found in these previous studies. The findings are discussed in terms of proposed cultural differences in the maintenance of human relations.

Human alteration of the rural landscape: Variations in visual perception

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cloquell-Ballester, Vicente-Agustin, E-mail: cloquell@dpi.upv.es; Carmen Torres-Sibille, Ana del; Cloquell-Ballester, Victor-Andres

2012-01-15

The objective of this investigation is to evaluate how visual perception varies as the rural landscape is altered by human interventions of varying character. An experiment is carried out using Semantic Differential Analysis to analyse the effect of the character and the type of the intervention on perception. Interventions are divided into elements of 'permanent industrial character', 'elements of permanent rural character' and 'elements of temporary character', and these categories are sub-divided into smaller groups according to the type of development. To increase the reliability of the results, the Intraclass Correlation Coefficient tool, is applied to validate the semantic spacemore » of the perceptual responses and to determine the number of subjects required for a reliable evaluation of the scenes.« less

Medical Image Databases

PubMed Central

Tagare, Hemant D.; Jaffe, C. Carl; Duncan, James

1997-01-01

Abstract Information contained in medical images differs considerably from that residing in alphanumeric format. The difference can be attributed to four characteristics: (1) the semantics of medical knowledge extractable from images is imprecise; (2) image information contains form and spatial data, which are not expressible in conventional language; (3) a large part of image information is geometric; (4) diagnostic inferences derived from images rest on an incomplete, continuously evolving model of normality. This paper explores the differentiating characteristics of text versus images and their impact on design of a medical image database intended to allow content-based indexing and retrieval. One strategy for implementing medical image databases is presented, which employs object-oriented iconic queries, semantics by association with prototypes, and a generic schema. PMID:9147338

The Effect of Signal-to-Noise Ratio on Linguistic Processing in a Semantic Judgment Task: An Aging Study.

PubMed

Stanley, Nicholas; Davis, Tara; Estis, Julie

2017-03-01

Aging effects on speech understanding in noise have primarily been assessed through speech recognition tasks. Recognition tasks, which focus on bottom-up, perceptual aspects of speech understanding, intentionally limit linguistic and cognitive factors by asking participants to only repeat what they have heard. On the other hand, linguistic processing tasks require bottom-up and top-down (linguistic, cognitive) processing skills and are, therefore, more reflective of speech understanding abilities used in everyday communication. The effect of signal-to-noise ratio (SNR) on linguistic processing ability is relatively unknown for either young (YAs) or older adults (OAs). To determine if reduced SNRs would be more deleterious to the linguistic processing of OAs than YAs, as measured by accuracy and reaction time in a semantic judgment task in competing speech. In the semantic judgment task, participants indicated via button press whether word pairs were a semantic Match or No Match. This task was performed in quiet, as well as, +3, 0, -3, and -6 dB SNR with two-talker speech competition. Seventeen YAs (20-30 yr) with normal hearing sensitivity and 17 OAs (60-68 yr) with normal hearing sensitivity or mild-to-moderate sensorineural hearing loss within age-appropriate norms. Accuracy, reaction time, and false alarm rate were measured and analyzed using a mixed design analysis of variance. A decrease in SNR level significantly reduced accuracy and increased reaction time in both YAs and OAs. However, poor SNRs affected accuracy and reaction time of Match and No Match word pairs differently. Accuracy for Match pairs declined at a steeper rate than No Match pairs in both groups as SNR decreased. In addition, reaction time for No Match pairs increased at a greater rate than Match pairs in more difficult SNRs, particularly at -3 and -6 dB SNR. False-alarm rates indicated that participants had a response bias to No Match pairs as the SNR decreased. Age-related differences were limited to No Match pair accuracies at -6 dB SNR. The ability to correctly identify semantically matched word pairs was more susceptible to disruption by a poor SNR than semantically unrelated words in both YAs and OAs. The effect of SNR on this semantic judgment task implies that speech competition differentially affected the facilitation of semantically related words and the inhibition of semantically incompatible words, although processing speed, as measured by reaction time, remained faster for semantically matched pairs. Overall, the semantic judgment task in competing speech elucidated the effect of a poor listening environment on the higher order processing of words. American Academy of Audiology

Neural division of labor in reading is constrained by culture: a training study of reading Chinese characters.

PubMed

Zhao, Jingjing; Wang, Xiaoyi; Frost, Stephen J; Sun, Wan; Fang, Shin-Yi; Mencl, W Einar; Pugh, Kenneth R; Shu, Hua; Rueckl, Jay G

2014-04-01

Word reading in alphabetic language involves a cortical system with multiple components whose division of labor depends on the transparency of the writing system. To gain insight about the neural division of labor between phonology and semantics subserving word reading in Chinese, a deep non-alphabetic writing system, functional magnetic resonance imaging (fMRI) was used to investigate the effects of phonological and semantic training on the cortical circuitry for oral naming of Chinese characters. In a training study, we examined whether a training task that differentially focused readers' attention on the phonological or semantic properties of a Chinese character changes the patterns of cortical activation that was evoked by that character in a subsequent naming task. Our imaging results corroborate that the cortical regions underlying reading in Chinese largely overlap the left-hemisphere reading system responsible for reading in alphabetic languages, with some cortical regions in the left-hemisphere uniquely recruited for reading in Chinese. However, in contrast to findings from studies of English word naming, we observed considerable overlap in the neural activation patterns associated with phonological and semantic training on naming Chinese characters, which we suggest may reflect a balanced neural division of labor between phonology and semantics in Chinese character reading. The equitable division of labor for Chinese reading might be driven by the special statistical structure of the writing system, which includes equally systematic mappings in the correspondences between written forms and their pronunciations and meanings. Copyright © 2014 Elsevier Ltd. All rights reserved.

Lost for emotion words: What motor and limbic brain activity reveals about autism and semantic theory

PubMed Central

Moseley, Rachel L.; Shtyrov, Yury; Mohr, Bettina; Lombardo, Michael V.; Baron-Cohen, Simon; Pulvermüller, Friedemann

2015-01-01

Autism spectrum conditions (ASC) are characterised by deficits in understanding and expressing emotions and are frequently accompanied by alexithymia, a difficulty in understanding and expressing emotion words. Words are differentially represented in the brain according to their semantic category and these difficulties in ASC predict reduced activation to emotion-related words in limbic structures crucial for affective processing. Semantic theories view ‘emotion actions’ as critical for learning the semantic relationship between a word and the emotion it describes, such that emotion words typically activate the cortical motor systems involved in expressing emotion actions such as facial expressions. As ASC are also characterised by motor deficits and atypical brain structure and function in these regions, motor structures would also be expected to show reduced activation during emotion-semantic processing. Here we used event-related fMRI to compare passive processing of emotion words in comparison to abstract verbs and animal names in typically-developing controls and individuals with ASC. Relatively reduced brain activation in ASC for emotion words, but not matched control words, was found in motor areas and cingulate cortex specifically. The degree of activation evoked by emotion words in the motor system was also associated with the extent of autistic traits as revealed by the Autism Spectrum Quotient. We suggest that hypoactivation of motor and limbic regions for emotion word processing may underlie difficulties in processing emotional language in ASC. The role that sensorimotor systems and their connections might play in the affective and social-communication difficulties in ASC is discussed. PMID:25278250

Speaking two "Languages" in America: A semantic space analysis of how presidential candidates and their supporters represent abstract political concepts differently.

PubMed

Li, Ping; Schloss, Benjamin; Follmer, D Jake

2017-10-01

In this article we report a computational semantic analysis of the presidential candidates' speeches in the two major political parties in the USA. In Study One, we modeled the political semantic spaces as a function of party, candidate, and time of election, and findings revealed patterns of differences in the semantic representation of key political concepts and the changing landscapes in which the presidential candidates align or misalign with their parties in terms of the representation and organization of politically central concepts. Our models further showed that the 2016 US presidential nominees had distinct conceptual representations from those of previous election years, and these patterns did not necessarily align with their respective political parties' average representation of the key political concepts. In Study Two, structural equation modeling demonstrated that reported political engagement among voters differentially predicted reported likelihoods of voting for Clinton versus Trump in the 2016 presidential election. Study Three indicated that Republicans and Democrats showed distinct, systematic word association patterns for the same concepts/terms, which could be reliably distinguished using machine learning methods. These studies suggest that given an individual's political beliefs, we can make reliable predictions about how they understand words, and given how an individual understands those same words, we can also predict an individual's political beliefs. Our study provides a bridge between semantic space models and abstract representations of political concepts on the one hand, and the representations of political concepts and citizens' voting behavior on the other.

To predict or not to predict: influences of task and strategy on the processing of semantic relations.

PubMed

Roehm, Dietmar; Bornkessel-Schlesewsky, Ina; Rösler, Frank; Schlesewsky, Matthias

2007-08-01

We report a series of event-related potential experiments designed to dissociate the functionally distinct processes involved in the comprehension of highly restricted lexical-semantic relations (antonyms). We sought to differentiate between influences of semantic relatedness (which are independent of the experimental setting) and processes related to predictability (which differ as a function of the experimental environment). To this end, we conducted three ERP studies contrasting the processing of antonym relations (black-white) with that of related (black-yellow) and unrelated (black-nice) word pairs. Whereas the lexical-semantic manipulation was kept constant across experiments, the experimental environment and the task demands varied: Experiment 1 presented the word pairs in a sentence context of the form The opposite of X is Y and used a sensicality judgment. Experiment 2 used a word pair presentation mode and a lexical decision task. Experiment 3 also examined word pairs, but with an antonymy judgment task. All three experiments revealed a graded N400 response (unrelated > related > antonyms), thus supporting the assumption that semantic associations are processed automatically. In addition, the experiments revealed that, in highly constrained task environments, the N400 gradation occurs simultaneously with a P300 effect for the antonym condition, thus leading to the superficial impression of an extremely "reduced" N400 for antonym pairs. Comparisons across experiments and participant groups revealed that the P300 effect is not only a function of stimulus constraints (i.e., sentence context) and experimental task, but that it is also crucially influenced by individual processing strategies used to achieve successful task performance.

Generation Y, wine and alcohol. A semantic differential approach to consumption analysis in Tuscany.

PubMed

Marinelli, Nicola; Fabbrizzi, Sara; Alampi Sottini, Veronica; Sacchelli, Sandro; Bernetti, Iacopo; Menghini, Silvio

2014-04-01

The aim of the study is the elicitation of the consumer's semantic perception of different alcoholic beverages in order to provide information for the definition of communication strategies for both the private sector (and specifically the wine industry) and the public decision maker. Such information can be seen as the basis of a wider social marketing construct aimed at the promotion of responsible drinking among young consumers. The semantic differential approach was used in this study. The data collection was based on a survey to 430 consumers between 18 and 35years old in Tuscany, Italy. The database was organized in a three-way structure, indexing the data in a multiway matrix. The data were processed using a Multiple Factor Analysis (MFA). Moreover, homogeneous clusters of consumers were identified using a Hierarchical Clustering on Principal Components (HCPC) approach. The results of the study highlight that beer and spirits are mainly perceived as "Young", "Social", "Euphoric", "Happy", "Appealing" and "Trendy" beverages, while wine is associated mostly with terms such as "Pleasure", "Quality" and "Comfortable". Furthermore, the cluster analysis allowed for the identification of three groups of individuals with different approaches to alcohol drinking. The results of the study supply a useful information framework for the elaboration of specific communication strategies that, based on the drinking habits of young consumers and their perception of different beverages, can use a language that is very close to the consumer typologies. Such information can be helpful for both private and public communication strategies. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

No grammatical gender effect on affective ratings: evidence from Italian and German languages.

PubMed

Montefinese, Maria; Ambrosini, Ettore; Roivainen, Eka

2018-06-06

In this study, we tested the linguistic relativity hypothesis by studying the effect of grammatical gender (feminine vs. masculine) on affective judgments of conceptual representation in Italian and German. In particular, we examined the within- and cross-language grammatical gender effect and its interaction with participants' demographic characteristics (such as, the raters' age and sex) on semantic differential scales (affective ratings of valence, arousal and dominance) in Italian and German speakers. We selected the stimuli and the relative affective measures from Italian and German adaptations of the ANEW (Affective Norms for English Words). Bayesian and frequentist analyses yielded evidence for the absence of within- and cross-languages effects of grammatical gender and sex- and age-dependent interactions. These results suggest that grammatical gender does not affect judgments of affective features of semantic representation in Italian and German speakers, since an overt coding of word grammar is not required. Although further research is recommended to refine the impact of the grammatical gender on properties of semantic representation, these results have implications for any strong view of the linguistic relativity hypothesis.

Dissociating linguistic and non-linguistic gesture processing: electrophysiological evidence from American Sign Language.

PubMed

Grosvald, Michael; Gutierrez, Eva; Hafer, Sarah; Corina, David

2012-04-01

A fundamental advance in our understanding of human language would come from a detailed account of how non-linguistic and linguistic manual actions are differentiated in real time by language users. To explore this issue, we targeted the N400, an ERP component known to be sensitive to semantic context. Deaf signers saw 120 American Sign Language sentences, each consisting of a "frame" (a sentence without the last word; e.g. BOY SLEEP IN HIS) followed by a "last item" belonging to one of four categories: a high-close-probability sign (a "semantically reasonable" completion to the sentence; e.g. BED), a low-close-probability sign (a real sign that is nonetheless a "semantically odd" completion to the sentence; e.g. LEMON), a pseudo-sign (phonologically legal but non-lexical form), or a non-linguistic grooming gesture (e.g. the performer scratching her face). We found significant N400-like responses in the incongruent and pseudo-sign contexts, while the gestures elicited a large positivity. Copyright © 2012 Elsevier Inc. All rights reserved.

Foveal splitting causes differential processing of Chinese orthography in the male and female brain.

PubMed

Hsiao, Janet Hui-Wen; Shillcock, Richard

2005-10-01

Chinese characters contain separate phonetic and semantic radicals. A dominant character type exists in which the semantic radical is on the left and the phonetic radical on the right; an opposite, minority structure also exists, with the semantic radical on the right and the phonetic radical on the left. We show that, when asked to pronounce isolated tokens of these two character types, males responded significantly faster when the phonetic information was on the right, whereas females showed a non-significant tendency in the opposite direction. Recent research on foveal structure and reading suggests that the two halves of a centrally fixated character are initially processed in different hemispheres. The male brain typically relies more on the left hemisphere for phonological processing compared with the female brain, causing this gender difference to emerge. This interaction is predicted by an implemented computational model. This study supports the existence of a gender difference in phonological processing, and shows that the effects of foveal splitting in reading extend far enough into word recognition to interact with the gender of the reader in a naturalistic reading task.

Individual differences in children's memory and reading comprehension: an investigation of semantic and inhibitory deficits.

PubMed

Cain, Kate

2006-07-01

Three experiments compared the verbal memory skills of children with poor reading comprehension with that of same-age good comprehenders. The aims were to determine if semantic and/or inhibitory deficits explained comprehenders' problems on measures of verbal short-term memory and verbal working memory. In Experiment 1 there were no group differences on word- and number-based measures of short-term storage and no evidence that semantic knowledge mediated word recall. In Experiment 2 poor comprehenders were impaired on word- and number-based assessments of working memory, the greatest deficit found on the word-based task. Error analysis of both word-based tasks revealed that poor comprehenders were more likely to recall items that should have been inhibited than were good comprehenders. Experiment 3 extended this finding: Poor comprehenders were less able to inhibit information that was no longer relevant. Together, these findings suggest that individual differences in inhibitory processing influence the ability to regulate the contents of working memory, which may contribute to the differential memory performance of good and poor comprehenders.

Depth of Processing and Age Differences.

PubMed

Kheirzadeh, Shiela; Pakzadian, Sarah Sadat

2016-10-01

The present article is aimed to investigate whether there are any differences between youngsters and adults in their working and long-term memory functioning. The theory of Depth of Processing (Craik and Lockhart in J Verbal Learning Verbal Behav 11:671-684, 1972) discusses the varying degrees of strengths of memory traces as the result of differential levels of processing on the retrieved input. Additionally, they claim that there are three levels of visual, auditory and semantic processes applied on the stimuli in the short-term memory leading to discrepancy in the durability of the memory traces and the later ease of recall and retrieval. In the present article, it is tried to demonstrate if there are evidences of more durable memory traces formed after semantic, visual and auditory processions of the incoming language data in two groups of (a) children in their language learning critical age and (b) youngsters who have passed the critical age period. The comparisons of the results made using two-way ANOVAs revealed the superiority of semantic processing for both age groups in recall, retention and consequently recognition of the new English vocabularies by EFL learners.

Dissociating linguistic and non-linguistic gesture processing: Electrophysiological evidence from American Sign Language

PubMed Central

Grosvald, Michael; Gutierrez, Eva; Hafer, Sarah; Corina, David

2012-01-01

A fundamental advance in our understanding of human language would come from a detailed account of how non-linguistic and linguistic manual actions are differentiated in real time by language users. To explore this issue, we targeted the N400, an ERP component known to be sensitive to semantic context. Deaf signers saw 120 American Sign Language sentences, each consisting of a “frame” (a sentence without the last word; e.g. BOY SLEEP IN HIS) followed by a “last item” belonging to one of four categories: a high-cloze-probability sign (a “semantically reasonable” completion to the sentence; e.g. BED), a low-cloze-probability sign (a real sign that is nonetheless a “semantically odd” completion to the sentence; e.g. LEMON), a pseudo-sign (phonologically legal but non-lexical form), or a non-linguistic grooming gesture (e.g. the performer scratching her face). We found significant N400-like responses in the incongruent and pseudo-sign contexts, while the gestures elicited a large positivity. PMID:22341555

Semantic evaluations of noise with tonal components in Japan, France, and Germany: a cross-cultural comparison.

PubMed

Hansen, Hans; Weber, Reinhard

2009-02-01

An evaluation of tonal components in noise using a semantic differential approach yields several perceptual and connotative factors. This study investigates the effect of culture on these factors with the aid of equivalent listening tests carried out in Japan (n=20), France (n=23), and Germany (n=20). The data's equivalence level is determined by a bias analysis. This analysis gives insight in the cross-cultural validity of the scales used for sound character determination. Three factors were extracted by factor analysis in all cultural subsamples: pleasant, metallic, and power. By employing appropriate target rotations of the factor spaces, the rotated factors were compared and they yield high similarities between the different cultural subsamples. To check cross-cultural differences in means, an item bias analysis was conducted. The a priori assumption of unbiased scales is rejected; the differences obtained are partially linked to bias effects. Acoustical sound descriptors were additionally tested for the semantic dimensions. The high agreement in judgments between the different cultural subsamples contrast the moderate success of the signal parameters to describe the dimensions.

Measurements and Analyses of Science Interest in a School District.

ERIC Educational Resources Information Center

Bauman, Daniel Joseph

Reported is a study to investigate the relationship of science interest with three instrument formats: scaled rating, block, and card sort. The scaled rating format was the same form as that used in Likert instruments. The block format was the graphic form used in the typical semantic differential where a single stem or concept is followed by…

Prototypical Images in Condom Scripts among AIDS-Bereaved Adolescents

ERIC Educational Resources Information Center

Reich, Warren A.; Rubin, Rachel M.

2007-01-01

Twenty-five HIV-negative late adolescents (13 women and 12 men) who had lost a parent to AIDS generated vignettes in which the characters were deciding whether to use a condom (condom scripts). Two clinically trained judges rated the interpersonal tone of the condom scripts on 17 semantic differential scales. Three other clinically trained raters…

Comparison of the Effects of Episodic Organizers and Traditional Notetaking on Story Recall. Final Report.

ERIC Educational Resources Information Center

Denner, Peter R.

Since the precise nature of the effects of notetaking encoding has not been clearly specified, a study involving 111 suburban seventh graders (southeastern Idaho) explored the differential effects of traditional notetaking and of episodic organizers (a type of semantic web or map) on the encoding of complex narrative passages. Subjects were…

Processing Biological Gender and Number Information during Chinese Pronoun Resolution: ERP Evidence for Functional Differentiation

ERIC Educational Resources Information Center

Xu, Xiaodong; Jiang, Xiaoming; Zhou, Xiaolin

2013-01-01

There have been a number of behavioral and neural studies on the processing of syntactic gender and number agreement information, marked by different morpho-syntactic features during sentence comprehension. By using the event-related potential (ERP) technique, the present study investigated whether the processing of semantic gender information and…

Six Differentiated Strategies for ESL Literacy for Birth to Third Grade Developmentally Disabled and Normal Students of Hispanic Heritage

ERIC Educational Resources Information Center

Jaramillo, James; Jaramillo, Olga

2013-01-01

When one effectively employs the strategies of exploratory-learning, wait-time, intervention, guided reading, meaning, and phonological-morphological-syntactical awareness-for infants and on up-to 3rd grade students-all-in a Montessori-like-learning-literacy-setting replete with semantical interactions with phonology, syllabology, morphology, and…

An Evaluation of the Experimental Anthropology Program at Magee Secondary School During the Spring Semester of 1973.

ERIC Educational Resources Information Center

Moodie, Allan G.; And Others

This study was performed to examine the effectiveness of an experimental anthropology program conducted in a secondary school. A semantic differential scale consisting of ten pairs of bipolar adjectives was administered in pre- and post-test sessions to anthropology students to measure their attitudes toward the following concepts: Culture,…

An Investigation of Differential Encoding and Retrieval in Older Adult College Students.

ERIC Educational Resources Information Center

Shaughnessy, Michael F.; Reif, Laurie

Three experiments were conducted in order to clarify the encoding/retrieval dilemma in older adult students; and the recognition/recall test issue was also explored. First, a mnemonic technique based on the "key word" method of Funk and Tarshis was used; secondly, a semantic processing task was tried; and lastly, a repetition task, based…

Effects of Age, Gender, and Causality on Perceptions of Persons with Mental Retardation

ERIC Educational Resources Information Center

Panek, Paul E.; Jungers, Melissa K.

2008-01-01

The present study examined the effects of age, gender, and causality on the perceptions of persons with mental retardation. Participants rated individuals with mental retardation using a semantic differential scale with three factors: activity, evaluation, and potency. Target individuals in each scenario varied on the variables of age (8, 20, 45),…

Attitudes of Business Students on the TARP Program: A Semantic Differential Analysis

ERIC Educational Resources Information Center

Piotrowski, Chris; Guyette, Roger W., Jr.

2011-01-01

The TARP program, a federal response to the 2008 financial crisis, has generated much debate both inside and outside of academia. Since business ethics, corporate responsibility, and public policy form the basic educational framework of the undergraduate business school curriculum, we investigated attitudes toward the TARP in the Spring of 2009.…

The Effects of 16 Hour Long Marathon Groups on the Ways that Female Drug Users Perceive Women.

ERIC Educational Resources Information Center

Page, Richard C.

1984-01-01

Evaluated the effectiveness of three 16-hour-long unstructured marathon groups composed of female illicit drug users in a woman's prison (N=78), using evaluative adjective pairs of the semantic differential concept Women. Marathon groups rated women as more successful and more pleasurable than did controls. (JAC)

Alumni Attitudes: Men and Women's Descriptions of Their College Experience, Present Work, and Present Recreational Activities.

ERIC Educational Resources Information Center

Jaynes, William E.; And Others

Alumni attitudes concerning their college experience, present work, and present recreational activities were analyzed in relation to the time in college, using a semantic differential format. Four items were used for each type of rating, one evaluative, another activity-oriented, and two potency oriented. The evaluation dimension concerns the…

The role of medial temporal lobe in retrieving spatial and nonspatial relations from episodic and semantic memory.

PubMed

Ryan, Lee; Lin, Chun-Yu; Ketcham, Katie; Nadel, Lynn

2010-01-01

This study examined the involvement of medial temporal lobe, especially the hippocampus, in processing spatial and nonspatial relations using episodic and semantic versions of a relational judgment task. Participants studied object arrays and were tested on different types of relations between pairs of objects. Three prevalent views of hippocampal function were considered. Cognitive map theory (O'Keefe and Nadel (1978) The Hippocampus as a Cognitive Map. USA: Oxford University Press) emphasizes hippocampal involvement in spatial relational tasks. Multiple trace theory (Nadel and Moscovitch (1997) Memory consolidation, retrograde amnesia and the hippocampal complex Curr Opin Neurobiol 7:217-227) emphasizes hippocampal involvement in episodic tasks. Eichenbaum and Cohen's ((2001) From Conditioning to Conscious Recollection: Memory Systems of the Brain. USA: Oxford University Press) relational theory predicts equivalent hippocampal involvement in all relational tasks within both semantic and episodic memory. The fMRI results provided partial support for all three theories, though none of them fit the data perfectly. We observed hippocampal activation during all relational tasks, with increased activation for spatial compared to nonspatial relations, and for episodic compared to semantic relations. The placement of activation along the anterior-posterior axis of the hippocampus also differentiated the conditions. We suggest a view of hippocampal function in memory that incorporates aspects of all three theories. Copyright 2009 Wiley-Liss, Inc.

The eyes reveal uncertainty about object distinctions in semantic variant primary progressive aphasia.

PubMed

Faria, Andreia V; Race, David; Kim, Kevin; Hillis, Argye E

2018-06-01

At least three distinct variants of primary progressive aphasia (PPA) have been described, but they are difficult to distinguish early in the course, when individuals experience primarily anomia. People with svPPA are often the hardest to care for, because they have impaired comprehension of words and objects and often have negative changes in comportment. We sought to identify an early marker of semantic variant primary progressive aphasia (svPPA) and to enhance the understanding of the semantic deficit in svPPA. We hypothesized that the pattern of eye tracking in a word picture matching task can differentiate svPPA from other variants and can predict which participants with unclassifiable PPA will progress to svPPA. We tested 19 individuals with PPA on a word picture matching task with eye tracking. We found that individuals with svPPA were less accurate than other variants when the foils were semantic coordinates (horse-cow) or schematically related (horse-saddle), but not when they were thematically related (saw-horse) or unrelated. Moreover, even in the condition in which they were highly accurate (unrelated foils) they looked much more often to the foils and for longer, than other variants or controls. Unclassifiable PPA participants who eventually developed svPPA showed the same pattern. This abnormal pattern was associated with atrophy in bilateral temporal poles. Copyright © 2018. Published by Elsevier Ltd.

Famous faces and voices: Differential profiles in early right and left semantic dementia and in Alzheimer's disease.

PubMed

Luzzi, Simona; Baldinelli, Sara; Ranaldi, Valentina; Fabi, Katia; Cafazzo, Viviana; Fringuelli, Fabio; Silvestrini, Mauro; Provinciali, Leandro; Reverberi, Carlo; Gainotti, Guido

2017-01-08

Famous face and voice recognition is reported to be impaired both in semantic dementia (SD) and in Alzheimer's Disease (AD), although more severely in the former. In AD a coexistence of perceptual impairment in face and voice processing has also been reported and this could contribute to the altered performance in complex semantic tasks. On the other hand, in SD both face and voice recognition disorders could be related to the prevalence of atrophy in the right temporal lobe (RTL). The aim of the present study was twofold: (1) to investigate famous faces and voices recognition in SD and AD to verify if the two diseases show a differential pattern of impairment, resulting from disruption of different cognitive mechanisms; (2) to check if face and voice recognition disorders prevail in patients with atrophy mainly affecting the RTL. To avoid the potential influence of primary perceptual problems in face and voice recognition, a pool of patients suffering from early SD and AD were administered a detailed set of tests exploring face and voice perception. Thirteen SD (8 with prevalence of right and 5 with prevalence of left temporal atrophy) and 25 CE patients, who did not show visual and auditory perceptual impairment, were finally selected and were administered an experimental battery exploring famous face and voice recognition and naming. Twelve SD patients underwent cerebral PET imaging and were classified in right and left SD according to the onset modality and to the prevalent decrease in FDG uptake in right or left temporal lobe respectively. Correlation of PET imaging and famous face and voice recognition was performed. Results showed a differential performance profile in the two diseases, because AD patients were significantly impaired in the naming tests, but showed preserved recognition, whereas SD patients were profoundly impaired both in naming and in recognition of famous faces and voices. Furthermore, face and voice recognition disorders prevailed in SD patients with RTL atrophy, who also showed a conceptual impairment on the Pyramids and Palm Trees test more important in the pictorial than in the verbal modality. Finally, in 12SD patients in whom PET was available, a strong correlation between FDG uptake and face-to-name and voice-to-name matching data was found in the right but not in the left temporal lobe. The data support the hypothesis of a different cognitive basis for impairment of face and voice recognition in the two dementias and suggest that the pattern of impairment in SD may be due to a loss of semantic representations, while a defect of semantic control, with impaired naming and preserved recognition might be hypothesized in AD. Furthermore, the correlation between face and voice recognition disorders and RTL damage are consistent with the hypothesis assuming that in the RTL person-specific knowledge may be mainly based upon non-verbal representations. Copyright © 2016 Elsevier Ltd. All rights reserved.

Cognitive Differences in Pictorial Reasoning between High-Functioning Autism and Asperger’s Syndrome

PubMed Central

Sahyoun, Cherif P.; Soulières, Isabelle; Belliveau, John W.; Mottron, Laurent; Mody, Maria

2013-01-01

We investigated linguistic and visuospatial processing during pictorial reasoning in high-functioning autism (HFA), Asperger’s syndrome (ASP), and age and IQ-matched typically developing participants (CTRL), using three conditions designed to differentially engage linguistic mediation or visuospatial processing (Visuospatial, V; Semantic, S; Visuospatial+Semantic, V+S). The three groups did not differ in accuracy, but showed different response time profiles. ASP and CTRL participants were fastest on V+S, amenable to both linguistic and nonlinguistic mediation, whereas HFA participants were equally fast on V and V+S, where visuospatial strategies were available, and slowest on S. HFA participants appeared to favor visuospatial over linguistic mediation. The results support the use of linguistic vs. visuospatial tasks for characterizing subtypes on the autism spectrum. PMID:19267190

The role of episodic memory in controlled evaluative judgments about attitudes: an event-related potential study.

PubMed

Johnson, Ray; Simon, Elizabeth J; Henkell, Heather; Zhu, John

2011-04-01

Event-related potentials (ERPs) are unique in their ability to provide information about the timing of activity in the neural networks that perform complex cognitive processes. Given the dearth of extant data from normal controls on the question of whether attitude representations are stored in episodic or semantic memory, the goal here was to study the nature of the memory representations used during conscious attitude evaluations. Thus, we recorded ERPs while participants performed three tasks: attitude evaluations (i.e., agree/disagree), autobiographical cued recall (i.e., You/Not You) and semantic evaluations (i.e., active/inactive). The key finding was that the parietal episodic memory (EM) effect, a well-established correlate of episodic recollection, was elicited by both attitude evaluations and autobiographical retrievals. By contrast, semantic evaluations of the same attitude items elicited less parietal activity, like that elicited by Not You cues, which only access semantic memory. In accord with hemodynamic results, attitude evaluations and autobiographical retrievals also produced overlapping patterns of slow potential (SP) activity from 500 to 900ms preceding the response over left and right inferior frontal, anterior medial frontal and occipital brain areas. Significantly different patterns of SP activity were elicited in these locations for semantic evaluations and Not You cues. Taken together, the results indicate that attitude representations are stored in episodic memory. Retrieval timing varied as a function of task, with earlier retrievals in both evaluation conditions relative to those in the autobiographical condition. The differential roles and timing of memory retrieval in evaluative judgment and memory retrieval tasks are discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

Semantic relation vs. surprise: the differential effects of related and unrelated co-verbal gestures on neural encoding and subsequent recognition.

PubMed

Straube, Benjamin; Meyer, Lea; Green, Antonia; Kircher, Tilo

2014-06-03

Speech-associated gesturing leads to memory advantages for spoken sentences. However, unexpected or surprising events are also likely to be remembered. With this study we test the hypothesis that different neural mechanisms (semantic elaboration and surprise) lead to memory advantages for iconic and unrelated gestures. During fMRI-data acquisition participants were presented with video clips of an actor verbalising concrete sentences accompanied by iconic gestures (IG; e.g., circular gesture; sentence: "The man is sitting at the round table"), unrelated free gestures (FG; e.g., unrelated up down movements; same sentence) and no gestures (NG; same sentence). After scanning, recognition performance for the three conditions was tested. Videos were evaluated regarding semantic relation and surprise by a different group of participants. The semantic relationship between speech and gesture was rated higher for IG (IG>FG), whereas surprise was rated higher for FG (FG>IG). Activation of the hippocampus correlated with subsequent memory performance of both gesture conditions (IG+FG>NG). For the IG condition we found activation in the left temporal pole and middle cingulate cortex (MCC; IG>FG). In contrast, for the FG condition posterior thalamic structures (FG>IG) as well as anterior and posterior cingulate cortices were activated (FG>NG). Our behavioral and fMRI-data suggest different mechanisms for processing related and unrelated co-verbal gestures, both of them leading to enhanced memory performance. Whereas activation in MCC and left temporal pole for iconic co-verbal gestures may reflect semantic memory processes, memory enhancement for unrelated gestures relies on the surprise response, mediated by anterior/posterior cingulate cortex and thalamico-hippocampal structures. Copyright © 2014 Elsevier B.V. All rights reserved.

The Differential Contributions of Conceptual Representation Format and Language Structure to Levels of Semantic Abstraction Capacity.

PubMed

Gainotti, Guido

2017-06-01

This paper reviews some controversies concerning the original and revised versions of the 'hub-and-spoke' model of conceptual representations and their implication for abstraction capacity levels. The 'hub-and-spoke' model, which is based on data gathered in patients with semantic dementia (SD), is the most authoritative model of conceptual knowledge. Patterson et al.'s (Nature Reviews Neuroscience, 8(12), 976-987, 2007) classical version of this model maintained that conceptual representations are stored in a unitary 'amodal' format in the right and left anterior temporal lobes (ATLs), because in SD the semantic disorder cuts across modalities and categories. Several authors questioned the unitary nature of these representations. They showed that the semantic impairment is 'multi-modal'only in the advanced stages of SD, when atrophy affects the ATLs bilaterally, but that impariments can be modality-specific in lateralised (early) stages of the disease. In these cases, SD mainly affects lexical-semantic knowledge when atrophy predominates on the left side and pictorial representations when atrophy prevails on the right side. Some aspects of the model (i.e. the importance of spokes, the multimodal format of representations and the graded convergence of modalities within the ATLs), which had already been outlined by Rogers et al. (Psychological Review, 111(1), 205-235, 2004) in a computational model of SD, were strengthened by these results. The relevance of these theoretical problems and of empirical data concerning the neural substrate of concrete and abstract words is discussed critically. The conclusion of the review is that the highest levels of abstraction are due more to the structuring influence of language than to the format of representations.

Biomarker validation of a decline in semantic processing in preclinical Alzheimer's disease.

PubMed

Papp, Kathryn V; Mormino, Elizabeth C; Amariglio, Rebecca E; Munro, Catherine; Dagley, Alex; Schultz, Aaron P; Johnson, Keith A; Sperling, Reisa A; Rentz, Dorene M

2016-07-01

Differentially worse performance on category versus letter fluency suggests greater semantic versus retrieval difficulties. This discrepancy, combined with reduced episodic memory, has widespread clinical utility in diagnosing Alzheimer's disease (AD). Our objective was to investigate whether changes in semantic processing, as measured by the discrepancy between category and letter fluency, was detectable in preclinical AD: in clinically normal older adults with abnormal β-amyloid (Aβ) deposition on positron emission tomography (PET) neuroimaging. Clinically normal older adults (mean Mini Mental State Exam (MMSE) score = 29) were classified as Aβ+ (n = 70) or Aβ- (n = 205) using Pittsburgh Compound B-(PET) imaging. Participants completed letter fluency (FAS; word generation to letters F-A-S) and category fluency (CAT; word generation to animals, vegetables, fruits) annually (mean follow-up = 2.42 years). The effect of Aβ status on fluency over time was examined using linear mixed models controlling for age, sex, and education. To dissociate effects related to semantic (CAT) versus retrieval processes (CAT and FAS), we repeated models predicting CAT over time, controlling for FAS and likewise for CAT controlling for FAS. At baseline, the Aβ+ group performed better on FAS compared with the Aβ- group but comparably on CAT. Longitudinally, the Aβ+ group demonstrated greater decline on CAT compared with the Aβ- group (p = .0011). This finding remained significant even when covarying for FAS (p = .0107). Aβ+ participants similarly declined compared with Aβ- participants on FAS (p = .0112), but this effect became insignificant when covarying for CAT (p = .1607). These findings provide biomarker validation for the greater specificity of declines in category versus letter fluency to underlying AD pathology. Our results also suggest that changes in semantic processing occur earlier in the AD trajectory than previously hypothesized. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

The processing of semantic relatedness in the brain: Evidence from associative and categorical false recognition effects following transcranial direct current stimulation of the left anterior temporal lobe.

PubMed

Díez, Emiliano; Gómez-Ariza, Carlos J; Díez-Álamo, Antonio M; Alonso, María A; Fernandez, Angel

2017-08-01

A dominant view of the role of the anterior temporal lobe (ATL) in semantic memory is that it serves as an integration hub, specialized in the processing of semantic relatedness by way of mechanisms that bind together information from different brain areas to form coherent amodal representations of concepts. Two recent experiments, using brain stimulation techniques along with the Deese-Roediger-McDermott (DRM) paradigm, have found a consistent false memory reduction effect following stimulation of the ATL, pointing to the importance of the ATL in semantic/conceptual processing. To more precisely identify the specific process being involved, we conducted a DRM experiment in which transcranial direct current stimulation (anode/cathode/sham) was applied over the participants' left ATL during the study of lists of words that were associatively related to their non-presented critical words (e.g., rotten, worm, red, tree, liqueur, unripe, cake, food, eden, peel, for the critical item apple) or categorically related (e.g., pear, banana, peach, orange, cantaloupe, watermelon, strawberry, cherry, kiwi, plum, for the same critical item apple). The results showed that correct recognition was not affected by stimulation. However, an interaction between stimulation condition and type of relation for false memories was found, explained by a significant false recognition reduction effect in the anodal condition for associative lists that was not observed for categorical lists. Results are congruent with previous findings and, more importantly, they help to clarify the nature and locus of false memory reduction effects, suggesting a differential role of the left ATL, and providing critical evidence for understanding the creation of semantic relatedness-based memory illusions. Copyright © 2017 Elsevier Ltd. All rights reserved.

An Attenuation of the "Normal" Category Effect in Patients with Alzheimer's Disease: A Review and Bootstrap Analysis

ERIC Educational Resources Information Center

Moreno-Martinez, F. Javier; Laws, Kieth R.

2007-01-01

There is a consensus that Alzheimer's disease (AD) impairs semantic information, with one of the first markers being anomia i.e. an impaired ability to name items. Doubts remain, however, about whether this naming impairment differentially affects items from the living and nonliving knowledge domains. Most studies have reported an impairment for…

Are Women Evaluated More Favorably than Men? An Analysis of Attitudes, Beliefs, and Emotions.

ERIC Educational Resources Information Center

Eagly, Alice H.; And Others

This study examined men's and women's attitudes toward the sexes, underlie these attitudes, and the ambivalence of this evaluative content. Male (N=162) and female (N=162) college students evaluated the social category of women or men on several types of measures: a semantic differential measure of attitudes, a free-response measure of beliefs, a…

Do Self Concept Tests Test Self Concept? An Evaluation of the Validity of Items on the Piers Harris and Coopersmith Measures.

ERIC Educational Resources Information Center

Lynch, Mervin D.; Chaves, John

Items from Peirs-Harris and Coopersmith self-concept tests were evaluated against independent measures on three self-constructs, idealized, empathic, and worth. Construct measurements were obtained with the semantic differential and D statistic. Ratings were obtained from 381 children, grades 4-6. For each test, item ratings and construct measures…

Diagnosing Changes in Attitude in First-Year College Chemistry Students with a Shortened Version of Bauer's Semantic Differential

ERIC Educational Resources Information Center

Brandriet, Alexandra R.; Xu, Xiaoying; Bretz, Stacey Lowery; Lewis, Jennifer E.

2011-01-01

In this quantitative study, a shortened version of the Attitude toward the Subject of Chemistry Inventory (ASCI) created by Bauer (2008) was used to identify the chemistry attitudes of two populations of general chemistry students at two universities. The ASCIv2 contained just two factors from the original instrument. These factors measured…

Snapshots of Children's Changing Biases during Language Development: Differential Weighting of Perceptual and Linguistic Factors Predicts Noun Age of Acquisition

ERIC Educational Resources Information Center

Ramey, Christopher H.; Chrysikou, Evangelia G.; Reilly, Jamie

2013-01-01

Word learning is a lifelong activity constrained by cognitive biases that people possess at particular points in development. Age of acquisition (AoA) is a psycholinguistic variable that may prove useful toward gauging the relative weighting of different phonological, semantic, and morphological factors at different phases of language acquisition…

The Use of Semantic Differential to Assess the Perceptions and Attitudes of Preservice and Advanced Degree Candidates Toward Various Exceptionalities.

ERIC Educational Resources Information Center

Stodden, Robert A.; Ianacone, Robert N.

The perceptions of three groups (n=30) of bachelor level special education majors and doctoral candidates in education toward the mentally retarded and various other exceptionalities were measured after exposure to three types of treatment. Of the three groups, the control group received no treatment, experimental group I received negative…

A Comparison of High School and College Student Attitudes toward Recreationally-Used Drugs.

ERIC Educational Resources Information Center

Minder, Carolyn; And Others

Research has shown that drug use tends to increase during the college years, implying that college students have a more favorable view of drug use than high school students. To compare the attitudes of high school (N=367) and college students (N=260) toward nine recreationally used drugs, a semantic differential technique was used. Statistically…

Perception of a Communication Source: An Examination of the Ideal Supervisor and Subordinate within a Military Organization.

ERIC Educational Resources Information Center

Hellweg, Susan A.

A study was designed to examine an underlying assumption regarding the use of the semantic differential in measuring the credibility and homophily of a communicator, namely, that responses to an ideal source position themselves at one extreme end of the scale, reflecting the monotonic function of the instrument such that the highest response…

Dissociating Linguistic and Non-Linguistic Gesture Processing: Electrophysiological Evidence from American Sign Language

ERIC Educational Resources Information Center

Grosvald, Michael; Gutierrez, Eva; Hafer, Sarah; Corina, David

2012-01-01

A fundamental advance in our understanding of human language would come from a detailed account of how non-linguistic and linguistic manual actions are differentiated in real time by language users. To explore this issue, we targeted the N400, an ERP component known to be sensitive to semantic context. Deaf signers saw 120 American Sign Language…

Clinical Study: Change in Outlook Towards Birth After a Midwife Led Antenatal Education Programme Versus Hypnoreflexogenous Self-Hypnosis Training for Childbirth

PubMed Central

Streibert, L. A.; Reinhard, J.; Yuan, J.; Schiermeier, S.; Louwen, F.

2015-01-01

Aim: To compare the change of maternal outlook towards birth due to a midwife led antenatal education programme versus hypnoreflexogenous self-hypnosis training for childbirth. Method: Before beginning of the classes and after the last class maternal perception on birth was evaluated using Osgood semantic differential questionnaire. The Gießen personality score was evaluated once. Results: 213 patients were enrolled in this study. 155 were in the midwife led education programme and 58 in the self-hypnosis training programme. There was no statistically significant difference between the two groups in regard of participantsʼ characteristics, Gießen personality score and initial Osgood semantic differential scores. After the midwife led course childbirth was emotionally more negatively scored (displeasure, tarnishing, dimension evaluation [p < 0.05]), whereas after the hypnosis course childbirth was emotionally more positively evaluated (pleasure, harmony, dimension evaluation [p < 0.01] and brightness [p < 0.05]). Summary: In this study hypnoreflexogenous self-hypnosis training resulted in a positive maternal outlook towards childbirth, in comparison to the midwife led course. Further prospective randomised studies are required to test these initial results. PMID:26719600

Differentiation and displacement: Unpicking the relationship between accounts of illness and social structure

PubMed Central

Gibson, Barry J; Paul, Ninu R

2014-01-01

This article seeks to unpack the relationship between social structure and accounts of illness. Taking dentine hypersensitivity as an example, this article explores the perspective that accounts of illness are sense-making processes that draw on a readily available pool of meaning. This pool of meaning is composed of a series of distinctions that make available a range of different lines of communication and action about such conditions. Such lines of communication are condensed and preserved over time and are often formed around a concept and its counter concept. The study of such processes is referred to as semantic analysis and involves drawing on the tools and techniques of conceptual history. This article goes on to explore how the semantics of dentine hypersensitivity developed. It illustrates how processes of social differentiation led to the concept being separated from the more dominant concept of dentine sensitivity and how it was medicalised, scientised and economised. In short, this study seeks to present the story of how society has developed a specific language for communicating about sensitivity and hypersensitivity in teeth. In doing so, it proposes that accounts of dentine hypersensitivity draw on lines of communication that society has preserved over time. PMID:25197262

Development of a Bone-Conducted Ultrasonic Hearing Aid for the Profoundly Deaf: Evaluation of Sound Quality Using a Semantic Differential Method

NASA Astrophysics Data System (ADS)

Nakagawa, Seiji; Fujiyuki, Chika; Kagomiya, Takayuki

2013-07-01

Bone-conducted ultrasound (BCU) is perceived even by the profoundly sensorineural deaf. A novel hearing aid using the perception of amplitude-modulated BCU (BCU hearing aid: BCUHA) has been developed. However, there is room for improvement particularly in terms of sound quality. BCU speech is accompanied by a strong high-pitched tone and contain some distortion. In this study, the sound quality of BCU speech with several types of amplitude modulation [double-sideband with transmitted carrier (DSB-TC), double-sideband with suppressed carrier (DSB-SC), and transposed modulations] and air-conducted (AC) speech was quantitatively evaluated using semantic differential and factor analysis. The results showed that all the types of BCU speech had higher metallic and lower esthetic factor scores than AC speech. On the other hand, transposed speech was closer than the other types of BCU speech to AC speech generally; the transposed speech showed a higher powerfulness factor score than the other types of BCU speech and a higher esthetic factor score than DSB-SC speech. These results provide useful information for further development of the BCUHA.

Is it advisable to include negative attributes to assess the stereotype content? Yes, but only in the morality dimension.

PubMed

Sayans-Jiménez, Pablo; Rojas Tejada, Antonio José; Cuadrado Guirado, Isabel

2017-04-01

Competence, morality and sociability dimensions have shown to be essential to measure stereotypes. Theoretically, the attributes associated with the negative pole of morality are more reliable and have shown to have higher evaluative weight. However, the current research usually employs only positive attributes to measure each dimension. Since the advantages of the inclusion of negative morality are clear it would be interesting to know about the effects of the inclusion of such type of attributes (i.e., it is good or bad for the measurement). The purpose of this study is to examine if the addition of negative items makes possible to improve the stereotype content measures. This study compares the differences between scales with various compositions of positive and negative items of stereotypes to predict three related variables: anger, fear and a semantic differential of evaluation. The study was carried out with a sample of 550 Spaniards. The data found highlights the importance of using attributes of the negative pole of morality in studying stereotypes. Their use was able to explain the intergroup emotional responses and the semantic differential more efficiently. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Objects and categories: feature statistics and object processing in the ventral stream.

PubMed

Tyler, Lorraine K; Chiu, Shannon; Zhuang, Jie; Randall, Billi; Devereux, Barry J; Wright, Paul; Clarke, Alex; Taylor, Kirsten I

2013-10-01

Recognizing an object involves more than just visual analyses; its meaning must also be decoded. Extensive research has shown that processing the visual properties of objects relies on a hierarchically organized stream in ventral occipitotemporal cortex, with increasingly more complex visual features being coded from posterior to anterior sites culminating in the perirhinal cortex (PRC) in the anteromedial temporal lobe (aMTL). The neurobiological principles of the conceptual analysis of objects remain more controversial. Much research has focused on two neural regions-the fusiform gyrus and aMTL, both of which show semantic category differences, but of different types. fMRI studies show category differentiation in the fusiform gyrus, based on clusters of semantically similar objects, whereas category-specific deficits, specifically for living things, are associated with damage to the aMTL. These category-specific deficits for living things have been attributed to problems in differentiating between highly similar objects, a process that involves the PRC. To determine whether the PRC and the fusiform gyri contribute to different aspects of an object's meaning, with differentiation between confusable objects in the PRC and categorization based on object similarity in the fusiform, we carried out an fMRI study of object processing based on a feature-based model that characterizes the degree of semantic similarity and difference between objects and object categories. Participants saw 388 objects for which feature statistic information was available and named the objects at the basic level while undergoing fMRI scanning. After controlling for the effects of visual information, we found that feature statistics that capture similarity between objects formed category clusters in fusiform gyri, such that objects with many shared features (typical of living things) were associated with activity in the lateral fusiform gyri whereas objects with fewer shared features (typical of nonliving things) were associated with activity in the medial fusiform gyri. Significantly, a feature statistic reflecting differentiation between highly similar objects, enabling object-specific representations, was associated with bilateral PRC activity. These results confirm that the statistical characteristics of conceptual object features are coded in the ventral stream, supporting a conceptual feature-based hierarchy, and integrating disparate findings of category responses in fusiform gyri and category deficits in aMTL into a unifying neurocognitive framework.

Tracing the time course of picture--word processing.

PubMed

Smith, M C; Magee, L E

1980-12-01

A number of independent lines of research have suggested that semantic and articulatory information become available differentially from pictures and words. The first of the experiments reported here sought to clarify the time course by which information about pictures and words becomes available by considering the pattern of interference generated when incongruent pictures and words are presented simultaneously in a Stroop-like situation. Previous investigators report that picture naming is easily disrupted by the presence of a distracting word but that word naming is relatively immune to interference from an incongruent picture. Under the assumption that information available from a completed process may disrupt an ongoing process, these results suggest that words access articulatory information more rapidly than do pictures. Experiment 1 extended this paradigm by requiring subjects to verify the category of the target stimulus. In accordance with the hypothesis that picture access the semantic code more rapidly than words, there was a reversal in the interference pattern: Word categorization suffered considerable disruption, whereas picture categorization was minimally affected by the presence of an incongruent word. Experiment 2 sought to further test the hypothesis that access to semantic and articulatory codes is different for pictures and words by examining memory for those items following naming or categorization. Categorized words were better recognized than named words, whereas the reverse was true for pictures, a result which suggests that picture naming involves more extensive processing than picture categorization. Experiment 3 replicated this result under conditions in which viewing time was held constant. The last experiment extended the investigation of memory differences to a situation in which subjects were required to generate the superordinate category name. Here, memory for categorized pictures was as good as memory for named pictures. Category generation also influenced memory for words, memory performance being superior to that following a yes--no verification of category membership. These experiments suggest a model of information access whereby pictures access semantic information were readily than name information, with the reverse being true for words. Memory for both pictures and words was a function of the amount of processing required to access a particular type of information as well as the extent of response differentiation necessitated by the task.

Patterns of neural activity predict picture-naming performance of a patient with chronic aphasia.

PubMed

Lee, Yune Sang; Zreik, Jihad T; Hamilton, Roy H

2017-01-08

Naming objects represents a substantial challenge for patients with chronic aphasia. This could be in part because the reorganized compensatory language networks of persons with aphasia may be less stable than the intact language systems of healthy individuals. Here, we hypothesized that the degree of stability would be instantiated by spatially differential neural patterns rather than either increased or diminished amplitudes of neural activity within a putative compensatory language system. We recruited a chronic aphasic patient (KL; 66 year-old male) who exhibited a semantic deficit (e.g., often said "milk" for "cow" and "pillow" for "blanket"). Over the course of four behavioral sessions involving a naming task performed in a mock scanner, we identified visual objects that yielded an approximately 50% success rate. We then conducted two fMRI sessions in which the patient performed a naming task for multiple exemplars of those objects. Multivoxel pattern analysis (MVPA) searchlight revealed differential activity patterns associated with correct and incorrect trials throughout intact brain regions. The most robust and largest cluster was found in the right occipito-temporal cortex encompassing fusiform cortex, lateral occipital cortex (LOC), and middle occipital cortex, which may account for the patient's propensity for semantic naming errors. None of these areas were found by a conventional univariate analysis. By using an alternative approach, we extend current evidence for compensatory naming processes that operate through spatially differential patterns within the reorganized language system. Copyright © 2016 Elsevier Ltd. All rights reserved.

iPixel: a visual content-based and semantic search engine for retrieving digitized mammograms by using collective intelligence.

PubMed

Alor-Hernández, Giner; Pérez-Gallardo, Yuliana; Posada-Gómez, Rubén; Cortes-Robles, Guillermo; Rodríguez-González, Alejandro; Aguilar-Laserre, Alberto A

2012-09-01

Nowadays, traditional search engines such as Google, Yahoo and Bing facilitate the retrieval of information in the format of images, but the results are not always useful for the users. This is mainly due to two problems: (1) the semantic keywords are not taken into consideration and (2) it is not always possible to establish a query using the image features. This issue has been covered in different domains in order to develop content-based image retrieval (CBIR) systems. The expert community has focussed their attention on the healthcare domain, where a lot of visual information for medical analysis is available. This paper provides a solution called iPixel Visual Search Engine, which involves semantics and content issues in order to search for digitized mammograms. iPixel offers the possibility of retrieving mammogram features using collective intelligence and implementing a CBIR algorithm. Our proposal compares not only features with similar semantic meaning, but also visual features. In this sense, the comparisons are made in different ways: by the number of regions per image, by maximum and minimum size of regions per image and by average intensity level of each region. iPixel Visual Search Engine supports the medical community in differential diagnoses related to the diseases of the breast. The iPixel Visual Search Engine has been validated by experts in the healthcare domain, such as radiologists, in addition to experts in digital image analysis.

Setting semantics: conceptual set can determine the physical properties that capture attention.

PubMed

Goodhew, Stephanie C; Kendall, William; Ferber, Susanne; Pratt, Jay

2014-08-01

The ability of a stimulus to capture visuospatial attention depends on the interplay between its bottom-up saliency and its relationship to an observer's top-down control set, such that stimuli capture attention if they match the predefined properties that distinguish a searched-for target from distractors (Folk, Remington, & Johnston, Journal of Experimental Psychology: Human Perception & Performance, 18, 1030-1044 1992). Despite decades of research on this phenomenon, however, the vast majority has focused exclusively on matches based on low-level physical properties. Yet if contingent capture is indeed a "top-down" influence on attention, then semantic content should be accessible and able to determine which physical features capture attention. Here we tested this prediction by examining whether a semantically defined target could create a control set for particular features. To do this, we had participants search to identify a target that was differentiated from distractors by its meaning (e.g., the word "red" among color words all written in black). Before the target array, a cue was presented, and it was varied whether the cue appeared in the physical color implied by the target word. Across three experiments, we found that cues that embodied the meaning of the word produced greater cuing than cues that did not. This suggests that top-down control sets activate content that is semantically associated with the target-defining property, and this content in turn has the ability to exogenously orient attention.

Preliminary Development of a Multidimensional Semantic Patient Experience Measurement Questionnaire.

PubMed

Kleiss, James A

2016-10-01

The purpose of this research was to assess the utility and reliability of a multidimensional patient experience measurement questionnaire in a clinical setting. Patient experience has emerged as an important metric for quality of healthcare. A number of separate concepts have been used to measure patient experience, but psychological research suggests that subjective experience is actually a composite of several independent concepts including: (a) evaluation/valence, (b) potency/control, (c) activity/arousal, and (d) novelty. The present research evaluates the reliability of a multidimensional patient experience measurement questionnaire in a clinical setting. A multidimensional semantic differential questionnaire was developed to measure the four underlying semantic dimensions of patient experience mentioned above. A group of 60 patients used the questionnaire to assess prescan expectations and postscan experience of a magnetic resonance scan. Data for one patient were deleted because their scan was interrupted. Results revealed more positive evaluation/valence, higher potency/control, and lower activity/arousal for postscan ratings compared to prescan expectations. Ratings of novelty were neutral in both the prescan and the postscan conditions. Subsequent analysis suggested that internal consistency for some concepts could be improved by replacing several specific rating scales. Present results provide evidence of the utility and reliability of a multidimensional semantic questionnaire for measuring patient experience in an actual clinical setting. Recommendations to improve internal consistency for the concepts potency/control, activity/arousal, and novelty were also provided. © The Author(s) 2016.

The canonical semantic network supports residual language function in chronic post-stroke aphasia

PubMed Central

Griffis, Joseph C.; Nenert, Rodolphe; Allendorfer, Jane B.; Vannest, Jennifer; Holland, Scott; Dietz, Aimee; Szaflarski, Jerzy P.

2016-01-01

Current theories of language recovery after stroke are limited by a reliance on small studies. Here, we aimed to test predictions of current theory and resolve inconsistencies regarding right hemispheric contributions to long-term recovery. We first defined the canonical semantic network in 43 healthy controls. Then, in a group of 43 patients with chronic post-stroke aphasia, we tested whether activity in this network predicted performance on measures of semantic comprehension, naming, and fluency while controlling for lesion volume effects. Canonical network activation accounted for 22–33% of the variance in language test scores. Whole-brain analyses corroborated these findings, and revealed a core set of regions showing positive relationships to all language measures. We next evaluated the relationship between activation magnitudes in left and right hemispheric portions of the network, and characterized how right hemispheric activation related to the extent of left hemispheric damage. Activation magnitudes in each hemispheric network were strongly correlated, but four right frontal regions showed heightened activity in patients with large lesions. Activity in two of these regions (inferior frontal gyrus pars opercularis and supplementary motor area) was associated with better language abilities in patients with larger lesions, but poorer language abilities in patients with smaller lesions. Our results indicate that bilateral language networks support language processing after stroke, and that right hemispheric activations related to extensive left hemisphere damage occur outside of the canonical semantic network and differentially relate to behavior depending on the extent of left hemispheric damage. PMID:27981674

It Takes Time to Prime: Semantic Priming in the Ocular Lexical Decision Task

PubMed Central

Hoedemaker, Renske S.; Gordon, Peter C.

2014-01-01

Two eye-tracking experiments were conducted in which the manual response mode typically used in lexical decision tasks (LDT) was replaced with an eye-movement response through a sequence of three words. This ocular LDT combines the explicit control of task goals found in LDTs with the highly practiced ocular response used in reading text. In Experiment 1, forward saccades indicated an affirmative LD on each word in the triplet. In Experiment 2, LD responses were delayed until all three letter strings had been read. The goal of the study was to evaluate the contribution of task goals and response mode to semantic priming. Semantic priming is very robust in tasks that involve recognition of words in isolation, such as LDT, while limited during text reading as measured using eye movements. Gaze durations in both experiments showed robust semantic priming even though ocular response times were much shorter than manual LDs for the same words in the English Lexicon Project. Ex-Gaussian distribution fits revealed that the priming effect was concentrated in estimates of τ, meaning that priming was most pronounced in the slow tail of the distribution. This pattern shows differential use of the prime information, which may be more heavily recruited in cases where the LD is difficult as indicated by longer response times. Compared to the manual LD responses, ocular LDs provide a more sensitive measure of this task-related influence on word recognition as measured by the LDT. PMID:25181368

Music Recognition in Frontotemporal Lobar Degeneration and Alzheimer Disease

PubMed Central

Johnson, Julene K; Chang, Chiung-Chih; Brambati, Simona M; Migliaccio, Raffaella; Gorno-Tempini, Maria Luisa; Miller, Bruce L; Janata, Petr

2013-01-01

Objective To compare music recognition in patients with frontotemporal dementia, semantic dementia, Alzheimer disease, and controls and to evaluate the relationship between music recognition and brain volume. Background Recognition of familiar music depends on several levels of processing. There are few studies about how patients with dementia recognize familiar music. Methods Subjects were administered tasks that assess pitch and melody discrimination, detection of pitch errors in familiar melodies, and naming of familiar melodies. Results There were no group differences on pitch and melody discrimination tasks. However, patients with semantic dementia had considerable difficulty naming familiar melodies and also scored the lowest when asked to identify pitch errors in the same melodies. Naming familiar melodies, but not other music tasks, was strongly related to measures of semantic memory. Voxel-based morphometry analysis of brain MRI showed that difficulty in naming songs was associated with the bilateral temporal lobes and inferior frontal gyrus, whereas difficulty in identifying pitch errors in familiar melodies correlated with primarily the right temporal lobe. Conclusions The results support a view that the anterior temporal lobes play a role in familiar melody recognition, and that musical functions are affected differentially across forms of dementia. PMID:21617528

Algorithmic Classification of Five Characteristic Types of Paraphasias.

PubMed

Fergadiotis, Gerasimos; Gorman, Kyle; Bedrick, Steven

2016-12-01

This study was intended to evaluate a series of algorithms developed to perform automatic classification of paraphasic errors (formal, semantic, mixed, neologistic, and unrelated errors). We analyzed 7,111 paraphasias from the Moss Aphasia Psycholinguistics Project Database (Mirman et al., 2010) and evaluated the classification accuracy of 3 automated tools. First, we used frequency norms from the SUBTLEXus database (Brysbaert & New, 2009) to differentiate nonword errors and real-word productions. Then we implemented a phonological-similarity algorithm to identify phonologically related real-word errors. Last, we assessed the performance of a semantic-similarity criterion that was based on word2vec (Mikolov, Yih, & Zweig, 2013). Overall, the algorithmic classification replicated human scoring for the major categories of paraphasias studied with high accuracy. The tool that was based on the SUBTLEXus frequency norms was more than 97% accurate in making lexicality judgments. The phonological-similarity criterion was approximately 91% accurate, and the overall classification accuracy of the semantic classifier ranged from 86% to 90%. Overall, the results highlight the potential of tools from the field of natural language processing for the development of highly reliable, cost-effective diagnostic tools suitable for collecting high-quality measurement data for research and clinical purposes.

Statistics and dynamics of attractor networks with inter-correlated patterns

NASA Astrophysics Data System (ADS)

Kropff, E.

2007-02-01

In an embodied feature representation view, the semantic memory represents concepts in the brain by the associated activation of the features that describe it, each one of them processed in a differentiated region of the cortex. This system has been modeled with a Potts attractor network. Several studies of feature representation show that the correlation between patterns plays a crucial role in semantic memory. The present work focuses on two aspects of the effect of correlations in attractor networks. In first place, it assesses how a Potts network can store a set of patterns with non-trivial correlations between them. This is done through a simple and biologically plausible modification to the classical learning rule. In second place, it studies the complexity of latching transitions between attractor states, and how this complexity can be controlled.

Perceptions of National Identity: How Adolescents in the United States and Norway View Their Own and Other Countries

ERIC Educational Resources Information Center

Zevin, Jack

2003-01-01

During the spring and summer 1999, to increase his understanding of the mental pictures that young adolescents hold of their own nation and other nations, the author interviewed students from four sociologically similar urban-area New York schools and students in a junior high school class in Oslo, Norway. He used a semantic differential survey…

The Relationship among Receptive and Expressive Vocabulary, Listening Comprehension, Pre-Reading Skills, Word Identification Skills, and Reading Comprehension by Children with Reading Disabilities

ERIC Educational Resources Information Center

Wise, Justin C.; Sevcik, Rose A.; Morris, Robin D.; Lovett, Maureen W.; Wolf, Maryanne

2007-01-01

Purpose: Some researchers (F. R. Vellutino, F. M. Scanlon, & M. S. Tanzman, 1994) have argued that the different domains comprising language (e.g., phonology, semantics, and grammar) may influence reading development in a differential manner and at different developmental periods. The purpose of this study was to examine proposed causal…

An Analysis of Differential Response Patterns on the Peabody Picture Vocabulary Test-IIIB in Struggling Adult Readers and Third-Grade Children

ERIC Educational Resources Information Center

Pae, Hye K.; Greenberg, Daphne; Williams, Rihana S.

2012-01-01

This study examines the Peabody Picture Vocabulary Test-IIIB (PPVT-IIIB) performance of 130 adults identified as struggling readers, in comparison to 175 third-grade children. Response patterns to the items on the PPVT-IIIB by these two groups were investigated, focusing on items, semantic categories, and lexical features, including word length,…

Differential contribution of left and right prefrontal cortex to associative cued-recall memory: a parametric PET study.

PubMed

Lepage, Martin

2004-03-01

Several brain imaging studies have implicated prefrontal regions bilaterally during cued-recall memory tasks and yet the functional significance of these regions remains poorly understood. Using PET, we examined the neural activity in prefrontal regions of 15 subjects while they performed three cued-recall tasks differing in pre-experimental semantic associations between cues and targets. This manipulation produced varying levels of retrieval performance when one member (a semantic category name) of the triad was used as a cue for the retrieval of the other two members. The percentage of items correctly recalled was 10, 46, and 70 in the low, medium, and high cued-recall conditions, respectively. Linear contrast analyses of the PET data identified brain regions where neural activity varied with the number of items retrieved from memory. A left lateral prefrontal region showed maximal activity during the high cued-recall condition, which likely reflects processes involved in retrieval success and possibly in the generation of memory responses. Three right prefrontal regions (anterior and dorsolateral) showed maximal activity during the low cued-recall condition, which likely reflects processes involved in memory search/monitoring. These findings add further support for a bilateral prefrontal contribution to memory cued-recall tasks and point to differential roles of the two hemispheres.

Semantic Classical Conditioning and Brain-Computer Interface Control: Encoding of Affirmative and Negative Thinking

PubMed Central

Ruf, Carolin A.; De Massari, Daniele; Furdea, Adrian; Matuz, Tamara; Fioravanti, Chiara; van der Heiden, Linda; Halder, Sebastian; Birbaumer, Niels

2013-01-01

The aim of the study was to investigate conditioned electroencephalography (EEG) responses to factually correct and incorrect statements in order to enable binary communication by means of a brain-computer interface (BCI). In two experiments with healthy participants true and false statements (serving as conditioned stimuli, CSs) were paired with two different tones which served as unconditioned stimuli (USs). The features of the USs were varied and tested for their effectiveness to elicit differentiable conditioned reactions (CRs). After acquisition of the CRs, these CRs to true and false statements were classified offline using a radial basis function kernel support vector machine. A mean single-trial classification accuracy of 50.5% was achieved for differentiating conditioned “yes” versus “no” thinking and mean accuracies of 65.4% for classification of “yes” and 68.8% for “no” thinking (both relative to baseline) were found using the best US. Analysis of the area under the curve of the conditioned EEG responses revealed significant differences between conditioned “yes” and “no” answers. Even though improvements are necessary, these first results indicate that the semantic conditioning paradigm could be a useful basis for further research regarding BCI communication in patients in the complete locked-in state. PMID:23471568

Emotional Complexity and the Neural Representation of Emotion in Motion

PubMed Central

Barnard, Philip J.; Lawrence, Andrew D.

2011-01-01

According to theories of emotional complexity, individuals low in emotional complexity encode and represent emotions in visceral or action-oriented terms, whereas individuals high in emotional complexity encode and represent emotions in a differentiated way, using multiple emotion concepts. During functional magnetic resonance imaging, participants viewed valenced animated scenarios of simple ball-like figures attending either to social or spatial aspects of the interactions. Participant’s emotional complexity was assessed using the Levels of Emotional Awareness Scale. We found a distributed set of brain regions previously implicated in processing emotion from facial, vocal and bodily cues, in processing social intentions, and in emotional response, were sensitive to emotion conveyed by motion alone. Attention to social meaning amplified the influence of emotion in a subset of these regions. Critically, increased emotional complexity correlated with enhanced processing in a left temporal polar region implicated in detailed semantic knowledge; with a diminished effect of social attention; and with increased differentiation of brain activity between films of differing valence. Decreased emotional complexity was associated with increased activity in regions of pre-motor cortex. Thus, neural coding of emotion in semantic vs action systems varies as a function of emotional complexity, helping reconcile puzzling inconsistencies in neuropsychological investigations of emotion recognition. PMID:20207691

Probing the links between language and mathematical conceptualisation

NASA Astrophysics Data System (ADS)

Bell, Garry; Woo, Jeong Ho

1998-04-01

Although it is well known that the number-naming grammars of some Asian languages affect the number conceptualisation and operational capacity of the young children who use them, language structure in other fields of the mathematical register appears to have been underemphasised in explanations of the differential mathematical attainment of East Asian and western students. This study probed the conceptual structures which samples of Year 9 students in Korea and Australia had constructed for various geometrical terms. The two samples of students exhibited major differences in definition ranking preferences on angle, and in semantic profiles for parallelogram, triangle, square, circle, cylinder, trapezium and line. It is hypothesised that these differences may be due in part to the noun phrase grammar differences between Korean and English, and to the syntax and semantic transparency of some Korean geometrical names. Results indicated reinforcement for the Vygotskian view that culturally imposed language structures directly influence the cognitive development of the learner.

The role of semantic memory in short-term recall: effect of strategic retrieval ability in an elderly population.

PubMed

Larigauderie, Pascale; Michaud, Aurelie; Vicente, Siobhan

2011-03-01

The present paper examines the relationship between two classic phenomena: semantic effects in short-term recall (STR) tasks, which are interpreted as indicating the involvement of long-term memory (LTM) in the functioning of short-term memory, on the one hand, and the existence of individual differences amongst elderly people in strategic retrieval ability (i.e., the ability to activate representations in LTM in a controlled way) on the other hand. Forty elderly participants completed a STR task under four different conditions which were thought to differentially involve LTM representations. Several executive functions, among which the strategic retrieval ability, were evaluated. The results showed that the participants who obtained the best performances in terms of strategic retrieval ability, and only in this executive ability, also exhibited better performances in the STR task, in particular when this task was performed under conditions which favored the use of LTM.

Differential lexical and semantic spreading activation in Alzheimer's disease.

PubMed

Foster, Paul S; Drago, Valeria; Yung, Raegan C; Pearson, Jaclyn; Stringer, Kristi; Giovannetti, Tania; Libon, David; Heilman, Kenneth M

2013-08-01

Alzheimer's disease (AD) is known to be associated with disruption in semantic networks. Previous studies examining changes in spreading activation in AD have used a lexical decision task paradigm. We have used a paradigm based on average word frequencies obtained from the words generated on the Controlled Oral Word Association Test (COWAT) and the Animal Naming (AN) test. The COWAT and AN tests were administered to a group of 25 patients with AD and 20 control participants. We predicted that the patients with AD would have higher average word frequencies on the COWAT and AN tests than the control participants. The results indicated that the AD group generated words with a higher average word frequency on the AN test but a lower average word frequency on the COWAT. The reasons for the discrepancy in average word frequencies on the AN test and COWAT are discussed.

Event-related brain potentials that distinguish false memory for events that occurred only seconds in the past.

PubMed

Chen, Hong; Voss, Joel L; Guo, Chunyan

2012-07-30

False memory often involves retrieving events from the distant past that did not actually happen. However, recent evidence obtained using the Deese/Roediger-McDermott (DRM) paradigm for eliciting false memory experiences suggests that individuals can falsely believe that events occurred mere seconds in the past when they in fact did not. Subjects in these experiments endorsed unstudied critical lure words as having been studied, despite the fact that word lists were studied just moments before. We identified event-related brain potential (ERP) correlates of this experience, and included a repetition priming manipulation to better assess the functional significance of these ERPs. Behavioral and ERP data were collected from 21 Capital Normal University students using a short-term DRM task. Two categories of effects were identified that distinguished true from false short-term memory: (1) early semantic priming effects from 300 to 500 ms and (2) later retrieval and retrieval-monitoring effects after 500 ms. The repetition priming manipulation had distinct influences on these effects, consistent with their differential associations with semantic priming versus episodic retrieval. Characterization of ERPs related to semantic priming and episodic retrieval provides important information regarding the mechanisms of short-term false memory. In contrast, most studies examining false memory in standard long-delay DRM paradigms identify ERP effects related only to retrieval monitoring. These findings highlight the neural processing involved in illusions of memory after very brief delays and highlight the role of semantic processing in short-term false memory.

Event-related brain potentials that distinguish false memory for events that occurred only seconds in the past

PubMed Central

2012-01-01

Background False memory often involves retrieving events from the distant past that did not actually happen. However, recent evidence obtained using the Deese/Roediger-McDermott (DRM) paradigm for eliciting false memory experiences suggests that individuals can falsely believe that events occurred mere seconds in the past when they in fact did not. Subjects in these experiments endorsed unstudied critical lure words as having been studied, despite the fact that word lists were studied just moments before. We identified event-related brain potential (ERP) correlates of this experience, and included a repetition priming manipulation to better assess the functional significance of these ERPs. Methods Behavioral and ERP data were collected from 21 Capital Normal University students using a short-term DRM task. Results Two categories of effects were identified that distinguished true from false short-term memory: (1) early semantic priming effects from 300 to 500 ms and (2) later retrieval and retrieval-monitoring effects after 500 ms. The repetition priming manipulation had distinct influences on these effects, consistent with their differential associations with semantic priming versus episodic retrieval. Conclusion Characterization of ERPs related to semantic priming and episodic retrieval provides important information regarding the mechanisms of short-term false memory. In contrast, most studies examining false memory in standard long-delay DRM paradigms identify ERP effects related only to retrieval monitoring. These findings highlight the neural processing involved in illusions of memory after very brief delays and highlight the role of semantic processing in short-term false memory. PMID:22846189

Early Childhood Stuttering and Electrophysiological Indices of Language Processing

PubMed Central

Weber-Fox, Christine; Wray, Amanda Hampton; Arnold, Hayley

2013-01-01

We examined neural activity mediating semantic and syntactic processing in 27 preschool-age children who stutter (CWS) and 27 preschool-age children who do not stutter (CWNS) matched for age, nonverbal IQ and language abilities. All participants displayed language abilities and nonverbal IQ within the normal range. Event-related brain potentials (ERPs) were elicited while participants watched a cartoon video and heard naturally spoken sentences that were either correct or contained semantic or syntactic (phrase structure) violations. ERPs in CWS, compared to CWNS, were characterized by longer N400 peak latencies elicited by semantic processing. In the CWS, syntactic violations elicited greater negative amplitudes for the early time window (150–350 ms) over medial sites compared to CWNS. Additionally, the amplitude of the P600 elicited by syntactic violations relative to control words was significant over the left hemisphere for the CWNS but showed the reverse pattern in CWS, a robust effect only over the right hemisphere. Both groups of preschoolage children demonstrated marked and differential effects for neural processes elicited by semantic and phrase structure violations; however, a significant proportion of young CWS exhibit differences in the neural functions mediating language processing compared to CWNS despite normal language abilities. These results are the first to show that differences in event-related brain potentials reflecting language processing occur as early as the preschool years in CWS and provide the first evidence that atypical lateralization of hemispheric speech/language functions previously observed in the brains of adults who stutter begin to emerge near the onset of developmental stuttering. PMID:23773672

Common and differential electrophysiological mechanisms underlying semantic object memory retrieval probed by features presented in different stimulus types.

PubMed

Chiang, Hsueh-Sheng; Eroh, Justin; Spence, Jeffrey S; Motes, Michael A; Maguire, Mandy J; Krawczyk, Daniel C; Brier, Matthew R; Hart, John; Kraut, Michael A

2016-08-01

How the brain combines the neural representations of features that comprise an object in order to activate a coherent object memory is poorly understood, especially when the features are presented in different modalities (visual vs. auditory) and domains (verbal vs. nonverbal). We examined this question using three versions of a modified Semantic Object Retrieval Test, where object memory was probed by a feature presented as a written word, a spoken word, or a picture, followed by a second feature always presented as a visual word. Participants indicated whether each feature pair elicited retrieval of the memory of a particular object. Sixteen subjects completed one of the three versions (N=48 in total) while their EEG were recorded simultaneously. We analyzed EEG data in four separate frequency bands (delta: 1-4Hz, theta: 4-7Hz; alpha: 8-12Hz; beta: 13-19Hz) using a multivariate data-driven approach. We found that alpha power time-locked to response was modulated by both cross-modality (visual vs. auditory) and cross-domain (verbal vs. nonverbal) probing of semantic object memory. In addition, retrieval trials showed greater changes in all frequency bands compared to non-retrieval trials across all stimulus types in both response-locked and stimulus-locked analyses, suggesting dissociable neural subcomponents involved in binding object features to retrieve a memory. We conclude that these findings support both modality/domain-dependent and modality/domain-independent mechanisms during semantic object memory retrieval. Copyright © 2016 Elsevier B.V. All rights reserved.

BeeSpace Navigator: exploratory analysis of gene function using semantic indexing of biological literature.

PubMed

Sen Sarma, Moushumi; Arcoleo, David; Khetani, Radhika S; Chee, Brant; Ling, Xu; He, Xin; Jiang, Jing; Mei, Qiaozhu; Zhai, ChengXiang; Schatz, Bruce

2011-07-01

With the rapid decrease in cost of genome sequencing, the classification of gene function is becoming a primary problem. Such classification has been performed by human curators who read biological literature to extract evidence. BeeSpace Navigator is a prototype software for exploratory analysis of gene function using biological literature. The software supports an automatic analogue of the curator process to extract functions, with a simple interface intended for all biologists. Since extraction is done on selected collections that are semantically indexed into conceptual spaces, the curation can be task specific. Biological literature containing references to gene lists from expression experiments can be analyzed to extract concepts that are computational equivalents of a classification such as Gene Ontology, yielding discriminating concepts that differentiate gene mentions from other mentions. The functions of individual genes can be summarized from sentences in biological literature, to produce results resembling a model organism database entry that is automatically computed. Statistical frequency analysis based on literature phrase extraction generates offline semantic indexes to support these gene function services. The website with BeeSpace Navigator is free and open to all; there is no login requirement at www.beespace.illinois.edu for version 4. Materials from the 2010 BeeSpace Software Training Workshop are available at www.beespace.illinois.edu/bstwmaterials.php.

Amnesia and the organization of the hippocampal system.

PubMed

Mishkin, M; Vargha-Khadem, F; Gadian, D G

1998-01-01

Early hippocampal injury in humans has been found to result in a limited form of global anterograde amnesia. At issue is whether the limitation is qualitative, with the amnesia reflecting substantially greater impairment in episodic than in semantic memory, or only quantitative, with both episodic and semantic memory being partially and equivalently impaired. Evidence from neuroanatomical and lesion studies in animals suggests that the hippocampus and subhippocampal cortices form a hierarchically organized system, such that the greatest convergence of information (and, by implication, the richest amount of association) takes place within the hippocampus, located at the top of the hierarchy. On the one hand, this evidence is consistent with the view that selective hippocampal damage produces a differential impairment in context-rich episodic memory as compared with context-free semantic memory, because only the latter can be supported by the subhippocampal cortices. On the other hand, given the system's hierarchical form of organization, this dissociation of deficits is difficult to prove, because a quantitatively limited deficit will nearly always be a viable alternative. A final choice between the alternative views is therefore likely to depend less on further evidence gathered in brain-injured patients than on which view accounts for more of the data gathered from converging approaches to the problem.

The language of future-thought: an fMRI study of embodiment and tense processing.

PubMed

Gilead, Michael; Liberman, Nira; Maril, Anat

2013-01-15

The ability to comprehend and represent the temporal properties of an occurrence is a crucial aspect of human language and cognition. Despite advances in neurolinguistic research into semantic processing, surprisingly little is known regarding the mechanisms which support the comprehension of temporal semantics. We used fMRI to investigate neural activity associated with processing of concrete and abstract sentences across the three temporal categories: past, present, and future. Theories of embodied cognition predict that concreteness-related activity would be evident in sensory and motor areas regardless of tense. Contrastingly, relying upon construal level theory we hypothesized that: (1) the neural markers associated with concrete language processing would appear for past and present tense sentences, but not for future sentences; (2) future tense sentences would activate intention-processing areas. Consistent with our first prediction, the results showed that activation in the parahippocampal gyrus differentiated between concrete and abstract sentences for past and present tense sentences, but not for future sentences. Not consistent with our second prediction, future tense sentences did not activate most of the regions that are implicated in the processing of intentions, but only activated the vmPFC. We discuss the implications of the current results to theories of embodied cognition and tense semantics. Copyright © 2012 Elsevier Inc. All rights reserved.

Beneficial effects of semantic memory support on older adults' episodic memory: Differential patterns of support of item and associative information.

PubMed

Mohanty, Praggyan Pam; Naveh-Benjamin, Moshe; Ratneshwar, Srinivasan

2016-02-01

The effects of two types of semantic memory support-meaningfulness of an item and relatedness between items-in mitigating age-related deficits in item and associative, memory are examined in a marketing context. In Experiment 1, participants studied less (vs. more) meaningful brand logo graphics (pictures) paired with meaningful brand names (words) and later were assessed by item (old/new) and associative (intact/recombined) memory recognition tests. Results showed that meaningfulness of items eliminated age deficits in item memory, while equivalently boosting associative memory for older and younger adults. Experiment 2, in which related and unrelated brand logo graphics and brand name pairs served as stimuli, revealed that relatedness between items eliminated age deficits in associative memory, while improving to the same degree item memory in older and younger adults. Experiment 2 also provided evidence for a probable boundary condition that could reconcile seemingly contradictory extant results. Overall, these experiments provided evidence that although the two types of semantic memory support can improve both item and associative memory in older and younger adults, older adults' memory deficits can be eliminated when the type of support provided is compatible with the type of information required to perform well on the test. (c) 2016 APA, all rights reserved).

Dynamics of human categorization in a collaborative tagging system: How social processes of semantic stabilization shape individual sensemaking.

PubMed

Ley, Tobias; Seitlinger, Paul

2015-10-01

We study how categories form and develop over time in a sensemaking task by groups of students employing a collaborative tagging system. In line with distributed cognition theories, we look at both the tags students use and their strength of representation in memory. We hypothesize that categories get more differentiated over time as students learn, and that semantic stabilization on the group level (i.e. the convergence in the use of tags) mediates this relationship. Results of a field experiment that tested the impact of topic study duration on the specificity of tags confirms these hypotheses, although it was not study duration that produced this effect, but rather the effectiveness of the collaborative taxonomy the groups built. In the groups with higher levels of semantic stabilization, we found use of more specific tags and better representation in memory. We discuss these findings with regard to the important role of the information value of tags that would drive both the convergence on the group level as well as a shift to more specific levels of categorization. We also discuss the implication for cognitive science research by highlighting the importance of collaboratively built artefacts in the process of how knowledge is acquired, and implications for educational applications of collaborative tagging environments.

Dynamics of human categorization in a collaborative tagging system: How social processes of semantic stabilization shape individual sensemaking

PubMed Central

Ley, Tobias; Seitlinger, Paul

2015-01-01

We study how categories form and develop over time in a sensemaking task by groups of students employing a collaborative tagging system. In line with distributed cognition theories, we look at both the tags students use and their strength of representation in memory. We hypothesize that categories get more differentiated over time as students learn, and that semantic stabilization on the group level (i.e. the convergence in the use of tags) mediates this relationship. Results of a field experiment that tested the impact of topic study duration on the specificity of tags confirms these hypotheses, although it was not study duration that produced this effect, but rather the effectiveness of the collaborative taxonomy the groups built. In the groups with higher levels of semantic stabilization, we found use of more specific tags and better representation in memory. We discuss these findings with regard to the important role of the information value of tags that would drive both the convergence on the group level as well as a shift to more specific levels of categorization. We also discuss the implication for cognitive science research by highlighting the importance of collaboratively built artefacts in the process of how knowledge is acquired, and implications for educational applications of collaborative tagging environments. PMID:26566299

The Investigation of Attitude Changes of Elementary Preservice Teachers in a Competency-Based, Field-Oriented Science Methods Course and Attitude Changes of Classroom Teachers Cooperating with the Field Component.

ERIC Educational Resources Information Center

Piper, Martha K.

Thirty-six students enrolled in an elementary science methods course were randomly selected and given an instrument using Osgood's semantic differential approach the first week of class, the sixth week on campus prior to field experiences, and the thirteenth week following field experiences. The elementary teachers who had observed the university…

Hemispheric encoding/retrieval asymmetry in episodic memory: positron emission tomography findings.

PubMed Central

Tulving, E; Kapur, S; Craik, F I; Moscovitch, M; Houle, S

1994-01-01

Data are reviewed from positron emission tomography studies of encoding and retrieval processes in episodic memory. These data suggest a hemispheric encoding/retrieval asymmetry model of prefrontal involvement in encoding and retrieval of episodic memory. According to this model, the left and right prefrontal lobes are part of an extensive neuronal network that subserves episodic remembering, but the two prefrontal hemispheres play different roles. Left prefrontal cortical regions are differentially more involved in retrieval of information from semantic memory and in simultaneously encoding novel aspects of the retrieved information into episodic memory. Right prefrontal cortical regions, on the other hand, are differentially more involved in episodic memory retrieval. PMID:8134342

Vocal reaction times to unilaterally presented concrete and abstract words: towards a theory of differential right hemispheric semantic processing.

PubMed

Rastatter, M; Dell, C W; McGuire, R A; Loren, C

1987-03-01

Previous studies investigating hemispheric organization for processing concrete and abstract nouns have provided conflicting results. Using manual reaction time tasks some studies have shown that the right hemisphere is capable of analyzing concrete words but not abstract. Others, however, have inferred that the left hemisphere is the sole analyzer of both types of lexicon. The present study tested these issues further by measuring vocal reaction times of normal subjects to unilaterally presented concrete and abstract items. Results were consistent with a model of functional localization which suggests that the minor hemisphere is capable of differentially processing both types of lexicon in the presence of a dominant left hemisphere.

Perceptions of submissiveness: implications for victimization.

PubMed

Richards, L; Rollerson, B; Phillips, J

1991-07-01

Some researchers have suggested that a precondition of affective submissiveness may increase the likelihood of female victimization in sexual assault, whereas others have suggested that criminal offenders use perceptions of vulnerability when selecting a victim. In this study, based on American college students, men (decoders) rated videotaped women (encoders) dominant versus submissive using a semantic differential instrument. Cue evaluators analyzed the body language and appearance of the videotaped women using a Likert instrument. The results suggest that (a) men form differentiated perceptions of dominant versus submissive women, (b) such perceptions substantially rely on nonverbal cues, (c) dominant and submissive women display visually different behaviors and appearances, and (d) men tend to select submissive females for exploitation.

Medial perirhinal cortex disambiguates confusable objects

PubMed Central

Tyler, Lorraine K.; Monsch, Andreas U.; Taylor, Kirsten I.

2012-01-01

Our brain disambiguates the objects in our cluttered visual world seemingly effortlessly, enabling us to understand their significance and to act appropriately. The role of anteromedial temporal structures in this process, particularly the perirhinal cortex, is highly controversial. In some accounts, the perirhinal cortex is necessary for differentiating between perceptually and semantically confusable objects. Other models claim that the perirhinal cortex neither disambiguates perceptually confusable objects nor plays a unique role in semantic processing. One major hurdle to resolving this central debate is the fact that brain damage in human patients typically encompasses large portions of the anteromedial temporal lobe, such that the identification of individual substructures and precise neuroanatomical locus of the functional impairments has been difficult. We tested these competing accounts in patients with Alzheimer’s disease with varying degrees of atrophy in anteromedial structures, including the perirhinal cortex. To assess the functional contribution of each anteromedial temporal region separately, we used a detailed region of interest approach. From each participant, we obtained magnetic resonance imaging scans and behavioural data from a picture naming task that contrasted naming performance with living and non-living things as a way of manipulating perceptual and semantic confusability; living things are more similar to one another than non-living things, which have more distinctive features. We manually traced neuroanatomical regions of interest on native-space cortical surface reconstructions to obtain mean thickness estimates for the lateral and medial perirhinal cortex and entorhinal cortex. Mean cortical thickness in each region of interest, and hippocampal volume, were submitted to regression analyses predicting naming performance. Importantly, atrophy of the medial perirhinal cortex, but not lateral perirhinal cortex, entorhinal cortex or hippocampus, significantly predicted naming performance on living relative to non-living things. These findings indicate that one specific anteromedial temporal lobe region—the medial perirhinal cortex—is necessary for the disambiguation of perceptually and semantically confusable objects. Taken together, these results support a hierarchical account of object processing, whereby the perirhinal cortex at the apex of the ventral object processing system is required to bind properties of not just perceptually, but also semantically confusable objects together, enabling their disambiguation from other similar objects and thus comprehension. Significantly, this model combining a hierarchical object processing architecture with a semantic feature statistic account explains why category-specific semantic impairments for living things are associated with anteromedial temporal lobe damage, and pinpoints the root of this syndrome to perirhinal cortex damage. PMID:23250887

A unified representation of findings in clinical radiology using the UMLS and DICOM.

PubMed

Bertaud, Valérie; Lasbleiz, Jérémy; Mougin, Fleur; Burgun, Anita; Duvauferrier, Régis

2008-09-01

Collecting and analyzing findings constitute the basis of medical activity. Computer assisted medical activity raises the problem of modelling findings. We propose a unified representation of findings integrating the representations of findings in the GAMUTS in Radiology [M.M. Reeder, B. Felson, GAMUTS in radiology Comprehensive lists of roentgen differential diagnosis, fourth ed., 2003], the Unified Medical Language System (UMLS), and the Digital Imaging and Communication in Medicine Structured Report (DICOM-SR). Starting from a corpus of findings in bone and joint radiology [M.M. Reeder, B. Felson, GAMUTS in Radiology comprehensive lists of roentgen differential diagnosis, fourth ed., 2003] (3481 words), an automated mapping to the UMLS was performed with the Metamap Program. The resulting UMLS terms and Semantic Types were analyzed in order to find a generic template in accordance with DICOM-SR structure. UMLS Concepts were missing for 45% of the GAMUTS findings. Three kinds of regularities were observed in the way the Semantic Types were combined: "pathological findings", "physiological findings" and "anatomical findings". A generic and original DICOM-SR template modelling finding was proposed. It was evaluated for representing GAMUTS jaws findings. 21% missing terms had to be picked up from Radlex (5%) or created (16%). This article shows that it is possible to represent findings using the UMLS and the DICOM SR formalism with a semi-automated method. The Metamap program helped to find a model to represent the semantic structure of free texts with standardized terms (UMLS Concepts). Nevertheless, the coverage of the UMLS is not comprehensive. This study shows that the UMLS should include more technical concepts and more concepts regarding findings, signs and symptoms to be suitable for radiology representation. The semi-automated translation of the whole GAMUTS using the UMLS concepts and the DICOM SR relations could help to create or supplement the DCMR Templates and Context Groups pertaining to the description of imaging findings.

The Semantic Distance Task: Quantifying Semantic Distance with Semantic Network Path Length

ERIC Educational Resources Information Center

Kenett, Yoed N.; Levi, Effi; Anaki, David; Faust, Miriam

2017-01-01

Semantic distance is a determining factor in cognitive processes, such as semantic priming, operating upon semantic memory. The main computational approach to compute semantic distance is through latent semantic analysis (LSA). However, objections have been raised against this approach, mainly in its failure at predicting semantic priming. We…

On the Antecedents of an Electrophysiological Signature of Retrieval Mode.

PubMed

Williams, Angharad N; Evans, Lisa H; Herron, Jane E; Wilding, Edward L

2016-01-01

It has been proposed that people employ a common set of sustained operations (retrieval mode) when preparing to remember different kinds of episodic information. In two experiments, however, there was no evidence for the pattern of brain activity commonly assumed to index these operations. In both experiments event-related potentials (ERPs) were recorded time-locked to alternating preparatory cues signalling that participants should prepare for different retrieval tasks. One cue signalled episodic retrieval: remember the location where the object was presented in a prior study phase. The other signalled semantic retrieval: identify the location where the object is most commonly found (Experiment 1) or identify the typical size of the object (Experiment 2). In both experiments, only two trials of the same task were completed in succession. This enabled ERP contrasts between 'repeat' trials (the cue on the preceding trial signalled the same retrieval task), and 'switch' trials (the cue differed from the preceding trial). There were differences between the ERPs elicited by the preparatory task cues in Experiment 1 only: these were evident only on switch trials and comprised more positive-going activity over right-frontal scalp for the semantic than for the episodic task. These findings diverge from previous outcomes where the activity differentiating cues signalling preparation for episodic or semantic retrieval has been restricted to right-frontal scalp sites, comprising more positive-going activity for the episodic than for the semantic task. While these findings are consistent with the view that there is not a common set of operations engaged when people prepare to remember different kinds of episodic information, an alternative account is offered here, which is that these outcomes are a consequence of structural and temporal components of the experiment designs.

Inborn and experience-dependent models of categorical brain organization. A position paper

PubMed Central

Gainotti, Guido

2015-01-01

The present review aims to summarize the debate in contemporary neuroscience between inborn and experience-dependent models of conceptual representations that goes back to the description of category-specific semantic disorders for biological and artifact categories. Experience-dependent models suggest that categorical disorders are the by-product of the differential weighting of different sources of knowledge in the representation of biological and artifact categories. These models maintain that semantic disorders are not really category-specific, because they do not respect the boundaries between different categories. They also argue that the brain structures which are disrupted in a given type of category-specific semantic disorder should correspond to the areas of convergence of the sensory-motor information which play a major role in the construction of that category. Furthermore, they provide a simple interpretation of gender-related categorical effects and are supported by studies assessing the importance of prior experience in the cortical representation of objects On the other hand, inborn models maintain that category-specific semantic disorders reflect the disruption of innate brain networks, which are shaped by natural selection to allow rapid identification of objects that are very relevant for survival. From the empirical point of view, these models are mainly supported by observations of blind subjects, which suggest that visual experience is not necessary for the emergence of category-specificity in the ventral stream of visual processing. The weight of the data supporting experience-dependent and inborn models is thoroughly discussed, stressing the fact observations made in blind subjects are still the subject of intense debate. It is concluded that at the present state of knowledge it is not possible to choose between experience-dependent and inborn models of conceptual representations. PMID:25667570

Modulation of the semantic system by word imageability.

PubMed

Sabsevitz, D S; Medler, D A; Seidenberg, M; Binder, J R

2005-08-01

A prevailing neurobiological theory of semantic memory proposes that part of our knowledge about concrete, highly imageable concepts is stored in the form of sensory-motor representations. While this theory predicts differential activation of the semantic system by concrete and abstract words, previous functional imaging studies employing this contrast have provided relatively little supporting evidence. We acquired event-related functional magnetic resonance imaging (fMRI) data while participants performed a semantic similarity judgment task on a large number of concrete and abstract noun triads. Task difficulty was manipulated by varying the degree to which the words in the triad were similar in meaning. Concrete nouns, relative to abstract nouns, produced greater activation in a bilateral network of multimodal and heteromodal association areas, including ventral and medial temporal, posterior-inferior parietal, dorsal prefrontal, and posterior cingulate cortex. In contrast, abstract nouns produced greater activation almost exclusively in the left hemisphere in superior temporal and inferior frontal cortex. Increasing task difficulty modulated activation mainly in attention, working memory, and response monitoring systems, with almost no effect on areas that were modulated by imageability. These data provide critical support for the hypothesis that concrete, imageable concepts activate perceptually based representations not available to abstract concepts. In contrast, processing abstract concepts makes greater demands on left perisylvian phonological and lexical retrieval systems. The findings are compatible with dual coding theory and less consistent with single-code models of conceptual representation. The lack of overlap between imageability and task difficulty effects suggests that once the neural representation of a concept is activated, further maintenance and manipulation of that information in working memory does not further increase neural activation in the conceptual store.

The Impact of Age, Background Noise, Semantic Ambiguity, and Hearing Loss on Recognition Memory for Spoken Sentences.

PubMed

Koeritzer, Margaret A; Rogers, Chad S; Van Engen, Kristin J; Peelle, Jonathan E

2018-03-15

The goal of this study was to determine how background noise, linguistic properties of spoken sentences, and listener abilities (hearing sensitivity and verbal working memory) affect cognitive demand during auditory sentence comprehension. We tested 30 young adults and 30 older adults. Participants heard lists of sentences in quiet and in 8-talker babble at signal-to-noise ratios of +15 dB and +5 dB, which increased acoustic challenge but left the speech largely intelligible. Half of the sentences contained semantically ambiguous words to additionally manipulate cognitive challenge. Following each list, participants performed a visual recognition memory task in which they viewed written sentences and indicated whether they remembered hearing the sentence previously. Recognition memory (indexed by d') was poorer for acoustically challenging sentences, poorer for sentences containing ambiguous words, and differentially poorer for noisy high-ambiguity sentences. Similar patterns were observed for Z-transformed response time data. There were no main effects of age, but age interacted with both acoustic clarity and semantic ambiguity such that older adults' recognition memory was poorer for acoustically degraded high-ambiguity sentences than the young adults'. Within the older adult group, exploratory correlation analyses suggested that poorer hearing ability was associated with poorer recognition memory for sentences in noise, and better verbal working memory was associated with better recognition memory for sentences in noise. Our results demonstrate listeners' reliance on domain-general cognitive processes when listening to acoustically challenging speech, even when speech is highly intelligible. Acoustic challenge and semantic ambiguity both reduce the accuracy of listeners' recognition memory for spoken sentences. https://doi.org/10.23641/asha.5848059.

Functional magnetic resonance imaging of neural activity related to orthographic, phonological, and lexico-semantic judgments of visually presented characters and words.

PubMed

Fujimaki, N; Miyauchi, S; Pütz, B; Sasaki, Y; Takino, R; Sakai, K; Tamada, T

1999-01-01

Functional magnetic resonance imaging was used to investigate neural activity during the judgment of visual stimuli in two groups of experiments using seven and five normal subjects. The subjects were given tasks designed differentially to involve orthographic (more generally, visual form), phonological, and lexico-semantic processes. These tasks included the judgments of whether a line was horizontal, whether a pseudocharacter or pseudocharacter string included a horizontal line, whether a Japanese katakana (phonogram) character or character string included a certain vowel, or whether a character string was meaningful (noun or verb) or meaningless. Neural activity related to the visual form process was commonly observed during judgments of both single real-characters and single pseudocharacters in lateral extrastriate visual cortex, the posterior ventral or medial occipito-temporal area, and the posterior inferior temporal area of both hemispheres. In contrast, left-lateralized activation was observed in the latter two areas during judgments of real- and pseudo-character strings. These results show that there is no katakana "word form center" whose activity is specific to real words. Activation related to the phonological process was observed, in Broca's area, the insula, the supramarginal gyrus, and the posterior superior temporal area, with greater activation in the left hemisphere. These activation foci for visual form and phonological processes of katakana also were reported for the English alphabet in previous studies. The present activation showed no additional areas for contrasts of noun judgment with other conditions and was similar between noun and verb judgment tasks, suggesting two possibilities: no strong semantic activation was produced, or the semantic process shared activation foci with the phonological process.

Mapping the Multiple Graded Contributions of the Anterior Temporal Lobe Representational Hub to Abstract and Social Concepts: Evidence from Distortion-corrected fMRI.

PubMed

Binney, Richard J; Hoffman, Paul; Lambon Ralph, Matthew A

2016-09-06

A growing body of recent convergent evidence indicates that the anterior temporal lobe (ATL) has connectivity-derived graded differences in semantic function: the ventrolateral region appears to be the transmodal, omni-category center-point of the hub whilst secondary contributions come from the peripheries of the hub in a manner that reflects their differential connectivity to different input/output modalities. One of the key challenges for this neurocognitive theory is how different types of concept, especially those with less reliance upon external sensory experience (such as abstract and social concepts), are coded across the graded ATL hub. We were able to answer this key question by using distortion-corrected fMRI to detect functional activations across the entire ATL region and thus to map the neural basis of social and psycholinguistically-matched abstract concepts. Both types of concept engaged a core left-hemisphere semantic network, including the ventrolateral ATL, prefrontal regions and posterior MTG. Additionally, we replicated previous findings of weaker differential activation of the superior and polar ATL for the processing of social stimuli, in addition to the stronger, omni-category activation observed in the vATL. These results are compatible with the view of the ATL as a graded transmodal substrate for the representation of coherent concepts. © The Author 2016. Published by Oxford University Press.

Mapping the Multiple Graded Contributions of the Anterior Temporal Lobe Representational Hub to Abstract and Social Concepts: Evidence from Distortion-corrected fMRI

PubMed Central

Binney, Richard J.; Hoffman, Paul; Lambon Ralph, Matthew A.

2016-01-01

A growing body of recent convergent evidence indicates that the anterior temporal lobe (ATL) has connectivity-derived graded differences in semantic function: the ventrolateral region appears to be the transmodal, omni-category center-point of the hub whilst secondary contributions come from the peripheries of the hub in a manner that reflects their differential connectivity to different input/output modalities. One of the key challenges for this neurocognitive theory is how different types of concept, especially those with less reliance upon external sensory experience (such as abstract and social concepts), are coded across the graded ATL hub. We were able to answer this key question by using distortion-corrected fMRI to detect functional activations across the entire ATL region and thus to map the neural basis of social and psycholinguistically-matched abstract concepts. Both types of concept engaged a core left-hemisphere semantic network, including the ventrolateral ATL, prefrontal regions and posterior MTG. Additionally, we replicated previous findings of weaker differential activation of the superior and polar ATL for the processing of social stimuli, in addition to the stronger, omni-category activation observed in the vATL. These results are compatible with the view of the ATL as a graded transmodal substrate for the representation of coherent concepts. PMID:27600844

Differentiating primary progressive aphasias in a brief sample of connected speech

PubMed Central

Evans, Emily; O'Shea, Jessica; Powers, John; Boller, Ashley; Weinberg, Danielle; Haley, Jenna; McMillan, Corey; Irwin, David J.; Rascovsky, Katya; Grossman, Murray

2013-01-01

Objective: A brief speech expression protocol that can be administered and scored without special training would aid in the differential diagnosis of the 3 principal forms of primary progressive aphasia (PPA): nonfluent/agrammatic PPA, logopenic variant PPA, and semantic variant PPA. Methods: We used a picture-description task to elicit a short speech sample, and we evaluated impairments in speech-sound production, speech rate, lexical retrieval, and grammaticality. We compared the results with those obtained by a longer, previously validated protocol and further validated performance with multimodal imaging to assess the neuroanatomical basis of the deficits. Results: We found different patterns of impaired grammar in each PPA variant, and additional language production features were impaired in each: nonfluent/agrammatic PPA was characterized by speech-sound errors; logopenic variant PPA by dysfluencies (false starts and hesitations); and semantic variant PPA by poor retrieval of nouns. Strong correlations were found between this brief speech sample and a lengthier narrative speech sample. A composite measure of grammaticality and other measures of speech production were correlated with distinct regions of gray matter atrophy and reduced white matter fractional anisotropy in each PPA variant. Conclusions: These findings provide evidence that large-scale networks are required for fluent, grammatical expression; that these networks can be selectively disrupted in PPA syndromes; and that quantitative analysis of a brief speech sample can reveal the corresponding distinct speech characteristics. PMID:23794681

Individual perception of bees: Between perceived danger and willingness to protect.

PubMed

Schönfelder, Mona Lisa; Bogner, Franz Xaver

2017-01-01

The current loss of biodiversity has found its way into the media. Especially the loss of bees as pollinators has recently received much attention aiming to increase public awareness about the consequence of pollinator loss and strategies for protection. However, pollinating insects like bees often prompt considerable anxiety. Negative emotions such as fear and disgust often lead to lack of support for conservation and appropriate initiatives for protection. Our study monitored perceptions of bees in the contexts of conservation and danger bees possibly represent by applying a semantic differential using contrasting adjectives under the heading "I think bees are…". Additionally, open questions were applied to examine individual perceptions of danger and conservation of bees. Respondents were students from primary school, secondary school and university. We compared these novices (n = 499) to experts (beekeepers, n = 153). An exploratory factor analysis of the semantic differential responses yielded three major oblique factors: Interest, Danger and Conservation & Usefulness. The inter-correlations of these factors were significant. Although all subgroups showed an overall high willingness to protect bees, the perception of danger scored medium. The individual experience of bee stings was the most prevalent reason for expressing fear. Educational programs focusing on pollinator conservation may reduce the perceived danger through removing misinformation, and supporting interest in the species. Based on the overall positive attitude toward bees, we suggest introducing bees (e.g., Apis mellifera) as a flagship species for pollinator conservation.

[Development of an attitude-measurement questionnaire using the semantic differential technique: defining the attitudes of radiological technology students toward X-ray examination].

PubMed

Tamura, Naomi; Terashita, Takayoshi; Ogasawara, Katsuhiko

2014-03-01

In general, it is difficult to objectively evaluate the results of an educational program. The semantic differential (SeD) technique, a methodology used to measure the connotative meaning of objects, words, and concepts, can, however, be applied to the evaluation of students' attitudes. In this study, we aimed to achieve an objective evaluation of the effects of radiological technology education. We therefore investigated the attitude of radiological students using the SeD technique. We focused on X-ray examinations in the field of radiological technology science. Bipolar adjective scales were used for the SeD questionnaire. To create the questionnaire, appropriate adjectives were selected from past reports of X-ray examination practice. The participants were 32 senior students at Hokkaido University at the Division of Radiological Technology at the School of Medicine's Department of Health Sciences. All the participants completed the questionnaire. The study was conducted in early June 2012. Attitudes toward X-ray examination were identified using a factor analysis of 11 adjectives. The factor analysis revealed the following three attitudes: feelings of expectation, responsibility, and resistance. Knowledge regarding the attitudes that students have toward X-ray examination will prove useful for evaluating the effects of educational intervention. In this study, a sampling bias may have occurred due to the small sample size; however, no other biases were observed.

Semantic Memory in the Clinical Progression of Alzheimer Disease.

PubMed

Tchakoute, Christophe T; Sainani, Kristin L; Henderson, Victor W

2017-09-01

Semantic memory measures may be useful in tracking and predicting progression of Alzheimer disease. We investigated relationships among semantic memory tasks and their 1-year predictive value in women with Alzheimer disease. We conducted secondary analyses of a randomized clinical trial of raloxifene in 42 women with late-onset mild-to-moderate Alzheimer disease. We assessed semantic memory with tests of oral confrontation naming, category fluency, semantic recognition and semantic naming, and semantic density in written narrative discourse. We measured global cognition (Alzheimer Disease Assessment Scale, cognitive subscale), dementia severity (Clinical Dementia Rating sum of boxes), and daily function (Activities of Daily Living Inventory) at baseline and 1 year. At baseline and 1 year, most semantic memory scores correlated highly or moderately with each other and with global cognition, dementia severity, and daily function. Semantic memory task performance at 1 year had worsened one-third to one-half standard deviation. Factor analysis of baseline test scores distinguished processes in semantic and lexical retrieval (semantic recognition, semantic naming, confrontation naming) from processes in lexical search (semantic density, category fluency). The semantic-lexical retrieval factor predicted global cognition at 1 year. Considered separately, baseline confrontation naming and category fluency predicted dementia severity, while semantic recognition and a composite of semantic recognition and semantic naming predicted global cognition. No individual semantic memory test predicted daily function. Semantic-lexical retrieval and lexical search may represent distinct aspects of semantic memory. Semantic memory processes are sensitive to cognitive decline and dementia severity in Alzheimer disease.

Differential Hemispheric Predilection of Microstructural White Matter and Functional Connectivity Abnormalities between Respectively Semantic and Behavioral Variant Frontotemporal Dementia.

PubMed

Meijboom, Rozanna; Steketee, Rebecca M E; Ham, Leontine S; van der Lugt, Aad; van Swieten, John C; Smits, Marion

2017-01-01

Semantic dementia (SD) and behavioral variant frontotemporal dementia (bvFTD), subtypes of frontotemporal dementia, are characterized by distinct clinical symptoms and neuroimaging features, with predominant left temporal grey matter (GM) atrophy in SD and bilateral or right frontal GM atrophy in bvFTD. Such differential hemispheric predilection may also be reflected by other neuroimaging features, such as brain connectivity. This study investigated white matter (WM) microstructure and functional connectivity differences between SD and bvFTD, focusing on the hemispheric predilection of these differences. Eight SD and 12 bvFTD patients, and 17 controls underwent diffusion tensor imaging and resting state functional MRI at 3T. Whole-brain WM microstructure was assessed to determine distinct WM tracts affected in SD and bvFTD. For these tracts, diffusivity measures and lateralization indices were calculated. Functional connectivity was established for GM regions affected in early stage SD or bvFTD. Results of a direct comparison between SD and bvFTD are reported. Whole-brain WM microstructure abnormalities were more pronounced in the left hemisphere in SD and bilaterally- with a slight predilection for the right- in bvFTD. Lateralization of tract-specific abnormalities was seen in SD only, toward the left hemisphere. Functional connectivity of disease-specific regions was mainly decreased bilaterally in SD and in the right hemisphere in bvFTD. SD and bvFTD show WM microstructure and functional connectivity abnormalities in different regions, that are respectively more pronounced in the left hemisphere in SD and in the right hemisphere in bvFTD. This indicates differential hemispheric predilection of brain connectivity abnormalities between SD and bvFTD.

Category specific deficits in Alzheimer's disease: fact or artefact?

PubMed

Tippett, Lynette J; Meier, Sandra L; Blackwood, Kirsty; Diaz-Asper, Catherine

2007-10-01

Impairments in semantic memory commonly occur in Alzheimer's Disease (AD) but do these occur along category-specific lines? We administered a confrontation naming task comprising living and nonliving items to 68 individuals with AD and 59 age-matched control participants, in a study designed to address some of the methodological issues affecting investigation of category effects. In Experiment 1, stimuli were matched for familiarity and word frequency and also visual complexity, and the AD group showed a differential deficit in nonliving things. In Experiment 2, however, living and nonliving stimuli were matched for age-of-acquisition, name agreement, word frequency, and naming accuracy of elderly controls and there was no categorical impairment in the AD group. The AD group was subdivided first into mild and moderate AD, and then into normal or impaired overall naming groups and performance was reanalysed, but there was still no significant category deficit in any group. Converging evidence was provided by hierarchical regressions across items, as age-of-acquisition, name agreement and word frequency were significant predictors of naming performance in mild and moderate AD groups, but category was not. In Experiment 3, stimulus items were matched for familiarity and naming accuracy of elderly controls when their performance was off-ceiling, and again no differential effect of category was found. When we reduced slightly how closely matched stimuli were for familiarity we then found a differential impairment in living things in the AD group. When reviewing the changing pattern of results from use of different stimulus sets, we concluded that the main determinant of whether or not a categorical impairment of either sort is found in AD is which stimulus properties are controlled during stimulus selection. We conclude that AD does not generally lead to a selective category loss in semantic knowledge.

Mining heart disease risk factors in clinical text with named entity recognition and distributional semantic models.

PubMed

Urbain, Jay

2015-12-01

We present the design, and analyze the performance of a multi-stage natural language processing system employing named entity recognition, Bayesian statistics, and rule logic to identify and characterize heart disease risk factor events in diabetic patients over time. The system was originally developed for the 2014 i2b2 Challenges in Natural Language in Clinical Data. The system's strengths included a high level of accuracy for identifying named entities associated with heart disease risk factor events. The system's primary weakness was due to inaccuracies when characterizing the attributes of some events. For example, determining the relative time of an event with respect to the record date, whether an event is attributable to the patient's history or the patient's family history, and differentiating between current and prior smoking status. We believe these inaccuracies were due in large part to the lack of an effective approach for integrating context into our event detection model. To address these inaccuracies, we explore the addition of a distributional semantic model for characterizing contextual evidence of heart disease risk factor events. Using this semantic model, we raise our initial 2014 i2b2 Challenges in Natural Language of Clinical data F1 score of 0.838 to 0.890 and increased precision by 10.3% without use of any lexicons that might bias our results. Copyright © 2015 Elsevier Inc. All rights reserved.

Dictionary Pruning with Visual Word Significance for Medical Image Retrieval

PubMed Central

Zhang, Fan; Song, Yang; Cai, Weidong; Hauptmann, Alexander G.; Liu, Sidong; Pujol, Sonia; Kikinis, Ron; Fulham, Michael J; Feng, David Dagan; Chen, Mei

2016-01-01

Content-based medical image retrieval (CBMIR) is an active research area for disease diagnosis and treatment but it can be problematic given the small visual variations between anatomical structures. We propose a retrieval method based on a bag-of-visual-words (BoVW) to identify discriminative characteristics between different medical images with Pruned Dictionary based on Latent Semantic Topic description. We refer to this as the PD-LST retrieval. Our method has two main components. First, we calculate a topic-word significance value for each visual word given a certain latent topic to evaluate how the word is connected to this latent topic. The latent topics are learnt, based on the relationship between the images and words, and are employed to bridge the gap between low-level visual features and high-level semantics. These latent topics describe the images and words semantically and can thus facilitate more meaningful comparisons between the words. Second, we compute an overall-word significance value to evaluate the significance of a visual word within the entire dictionary. We designed an iterative ranking method to measure overall-word significance by considering the relationship between all latent topics and words. The words with higher values are considered meaningful with more significant discriminative power in differentiating medical images. We evaluated our method on two public medical imaging datasets and it showed improved retrieval accuracy and efficiency. PMID:27688597

Dictionary Pruning with Visual Word Significance for Medical Image Retrieval.

PubMed

Zhang, Fan; Song, Yang; Cai, Weidong; Hauptmann, Alexander G; Liu, Sidong; Pujol, Sonia; Kikinis, Ron; Fulham, Michael J; Feng, David Dagan; Chen, Mei

2016-02-12

Content-based medical image retrieval (CBMIR) is an active research area for disease diagnosis and treatment but it can be problematic given the small visual variations between anatomical structures. We propose a retrieval method based on a bag-of-visual-words (BoVW) to identify discriminative characteristics between different medical images with Pruned Dictionary based on Latent Semantic Topic description. We refer to this as the PD-LST retrieval. Our method has two main components. First, we calculate a topic-word significance value for each visual word given a certain latent topic to evaluate how the word is connected to this latent topic. The latent topics are learnt, based on the relationship between the images and words, and are employed to bridge the gap between low-level visual features and high-level semantics. These latent topics describe the images and words semantically and can thus facilitate more meaningful comparisons between the words. Second, we compute an overall-word significance value to evaluate the significance of a visual word within the entire dictionary. We designed an iterative ranking method to measure overall-word significance by considering the relationship between all latent topics and words. The words with higher values are considered meaningful with more significant discriminative power in differentiating medical images. We evaluated our method on two public medical imaging datasets and it showed improved retrieval accuracy and efficiency.

Production of Verb Tense in Agrammatic Aphasia: A Meta-Analysis and Further Data

PubMed Central

Faroqi-Shah, Yasmeen; Friedman, Laura

2015-01-01

In a majority of languages, the time of an event is expressed by marking tense on the verb. There is substantial evidence that the production of verb tense in sentences is more severely impaired than other functional categories in persons with agrammatic aphasia. The underlying source of this verb tense impairment is less clear, particularly in terms of the relative contribution of conceptual-semantic and processing demands. This study aimed to provide a more precise characterization of verb tense impairment by examining if there is dissociation within tenses (due to conceptual-semantic differences) and an effect of experimental task (mediated by processing limitations). Two sources of data were used: a meta-analysis of published research (which yielded 143 datasets) and new data from 16 persons with agrammatic aphasia. Tensed verbs were significantly more impaired than neutral (nonfinite) verbs, but there were no consistent differences between past, present, and future tenses. Overall, tense accuracy was mediated by task, such that picture description task was the most challenging, relative to sentence completion, sentence production priming, and grammaticality judgment. An interaction between task and tense revealed a past tense disadvantage for a sentence production priming task. These findings indicate that verb tense impairment is exacerbated by processing demands of the elicitation task and the conceptual-semantic differences between tenses are too subtle to show differential performance in agrammatism. PMID:26457004

New comparison of psychological meaning of colors in samples and objects with semantic ratings

NASA Astrophysics Data System (ADS)

Lee, Tien-Rein

2002-06-01

In color preference and color-meaning research, color chips are widely used as stimuli. Are meanings of isolated color chips generalizeable to contextualized colors? According to Taft (1996), few significant differences exist between chip and object ratings for the same color. A similar survey was performed on 192 college students. This article reports the results of the study comparing semantic rating of color applied to a variety of familiar objects. The objects were a cup, T-shirt, sofa, car, notebook, and MP3 player, all images that represent daily life familiar objects. Subjects rated a set of 16 color chips, against 6 bipolar, 7-step semantic differential scales. The scales consisted of beautiful-ugly, soft-hard, warm-cool, elegant-vulgar, loud- discreet, and masculine-feminine. Analyses performed on the data indicated that unlike Taft's findings on 1996, significant differences existed between chip and object rating for the same color in every scale. The results of the study have implications for the use of color chips in color planning which suggest they are not compatible with the generality of results of the earlier color meaning research. Generally, a color judged to be beautiful, elegant and warm when presented as a chip does not equal beautiful, elegant, and warm when applied to the surface of an object such as a cup, T-shirt, sofa, car.

The effect of word length and other sublexical, lexical, and semantic variables on developmental reading deficits.

PubMed

De Luca, Maria; Barca, Laura; Burani, Cristina; Zoccolotti, Pierluigi

2008-12-01

To examine the effect of word length and several sublexical, and lexico-semantic variables on the reading of Italian children with a developmental reading deficit. Previous studies indicated the role of word length in transparent orthographies. However, several factors that may interact with word length were not controlled for. Seventeen impaired and 34 skilled sixth-grade readers were presented words of different lengths, matched for initial phoneme, bigram frequency, word frequency, age of acquisition, and imageability. Participants were asked to read aloud, as quickly and as accurately as possible. Reaction times at the onset of pronunciation and mispronunciations were recorded. Impaired readers' reaction times indicated a marked effect of word length; in skilled readers, there was no length effect for short words but, rather, a monotonic increase from 6-letter words on. Regression analyses confirmed the role of word length and indicated the influence of word frequency (similar in impaired and skilled readers). No other variables predicted reading latencies. Word length differentially influenced word recognition in impaired versus skilled readers, irrespective of the action of (potentially interfering) sublexical, lexical, and semantic variables. It is proposed that the locus of the length effect is at a perceptual level of analysis. The independent influence of word frequency on the reading performance of both groups of participants indicates the sparing of lexical activation in impaired readers.

Integrating Conceptual Knowledge Within and Across Representational Modalities

PubMed Central

McNorgan, Chris; Reid, Jackie; McRae, Ken

2011-01-01

Research suggests that concepts are distributed across brain regions specialized for processing information from different sensorimotor modalities. Multimodal semantic models fall into one of two broad classes differentiated by the assumed hierarchy of convergence zones over which information is integrated. In shallow models, communication within- and between-modality is accomplished using either direct connectivity, or a central semantic hub. In deep models, modalities are connected via cascading integration sites with successively wider receptive fields. Four experiments provide the first direct behavioral tests of these models using speeded tasks involving feature inference and concept activation. Shallow models predict no within-modal versus cross-modal difference in either task, whereas deep models predict a within-modal advantage for feature inference, but a cross-modal advantage for concept activation. Experiments 1 and 2 used relatedness judgments to tap participants’ knowledge of relations for within- and cross-modal feature pairs. Experiments 3 and 4 used a dual feature verification task. The pattern of decision latencies across Experiments 1 to 4 is consistent with a deep integration hierarchy. PMID:21093853

Event-related brain potentials to violations of arithmetic syntax represented by place value structure.

PubMed

Szucs, Dénes; Soltész, Fruzsina

2010-05-01

We dissociated ERP markers of semantic (numerical distance) vs. syntactic (place value) incongruence in the domain of arithmetic. Participants verified additions with four-digit numbers. Semantic incongruencies elicited the N400 ERP effect. A centro-parietal (putative P600) effect to place value violations was not related to arithmetic syntax. Rather, this effect was an enlarged P3b reflecting different surprise values of place value vs. non-place value violations. This potential confound should be considered in numerical cognition experiments. The latency of the N400 and P3a effects were differentially affected by place value analysis. The amplitude of the P3a and that of a fronto-central positive effect (FP600) was sensitive to place value analysis and digit content. Results suggest that ERPs can index the syntactical analysis of multi-digit numbers. Both ERP and behavioral data confirmed that multi-digit numbers were decomposed into their constituent digits, rather than evaluated holistically. Copyright 2010 Elsevier B.V. All rights reserved.

Effects of plausibility on structural priming.

PubMed

Christianson, Kiel; Luke, Steven G; Ferreira, Fernanda

2010-03-01

We report a replication and extension of Ferreira (2003), in which it was observed that native adult English speakers misinterpret passive sentences that relate implausible but not impossible semantic relationships (e.g., The angler was caught by the fish) significantly more often than they do plausible passives or plausible or implausible active sentences. In the experiment reported here, participants listened to the same plausible and implausible passive and active sentences as in Ferreira (2003), answered comprehension questions, and then orally described line drawings of simple transitive actions. The descriptions were analyzed as a measure of structural priming (Bock, 1986). Question accuracy data replicated Ferreira (2003). Production data yielded an interaction: Passive descriptions were produced more often after plausible passives and implausible actives. We interpret these results as indicative of a language processor that proceeds along differentiated morphosyntactic and semantic routes. The processor may end up adjudicating between conflicting outputs from these routes by settling on a "good enough" representation that is not completely faithful to the input.

Ambivalent sexism and attitudes toward women in different stages of reproductive life: a semantic, cross-cultural approach.

PubMed

Chrisler, Joan C; Gorman, Jennifer A; Marván, Maria Luisa; Johnston-Robledo, Ingrid

2014-01-01

College students in southeastern Mexico (n = 185) and the northeastern United States (n = 96) utilized a semantic differential scale to rate subtypes of women: a menstruating woman, a menopausal woman, a pregnant woman, a premenstrual woman, a woman with a hysterectomy, a teenage girl, a woman in love, and a woman with a young baby. Americans reported significantly more negative attitudes than Mexicans did toward a menstruating woman, a premenstrual woman, a teenage girl, and a pregnant woman. Participants chose more positive words to describe a teenage girl, a woman in love, a pregnant woman, and a woman with a young baby, which is suggestive of a pronatal bias. Participants also completed the Ambivalent Sexism Inventory (ASI). Men scored significantly higher than women on hostile sexism. Mexicans scored significantly higher than Americans on both hostile and benevolent sexism. Sexism scores are related to attitudes toward premenstrual, menstruating, and menopausal women; women with a hysterectomy; and women with a young baby.

Masked priming and ERPs dissociate maturation of orthographic and semantic components of visual word recognition in children

PubMed Central

Eddy, Marianna D.; Grainger, Jonathan; Holcomb, Phillip J.; Mitra, Priya; Gabrieli, John D. E.

2014-01-01

This study examined the time-course of reading single words in children and adults using masked repetition priming and the recording of event-related potentials. The N250 and N400 repetition priming effects were used to characterize form- and meaning-level processing, respectively. Children had larger amplitude N250 effects than adults for both shorter and longer duration primes. Children did not differ from adults on the N400 effect. The difference on the N250 suggests that automaticity for form processing is still maturing in children relative to adults, while the lack of differentiation on the N400 effect suggests that meaning processing is relatively mature by late childhood. The overall similarity in the children’s repetition priming effects to adults’ effects is in line with theories of reading acquisition, according to which children rapidly transition to an orthographic strategy for fast access to semantic information from print. PMID:24313638

Creative thinking as orchestrated by semantic processing vs. cognitive control brain networks.

PubMed

Abraham, Anna

2014-01-01

Creativity is primarily investigated within the neuroscientific perspective as a unitary construct. While such an approach is beneficial when trying to infer the general picture regarding creativity and brain function, it is insufficient if the objective is to uncover the information processing brain mechanisms by which creativity occurs. As creative thinking emerges through the dynamic interplay between several cognitive processes, assessing the neural correlates of these operations would enable the development and characterization of an information processing framework from which to better understand this complex ability. This article focuses on two aspects of creative cognition that are central to generating original ideas. "Conceptual expansion" refers to the ability to widen one's conceptual structures to include unusual or novel associations, while "overcoming knowledge constraints" refers to our ability to override the constraining influence imposed by salient or pertinent knowledge when trying to be creative. Neuroimaging and neuropsychological evidence is presented to illustrate how semantic processing and cognitive control networks in the brain differentially modulate these critical facets of creative cognition.

Over-the-counter pharmaceuticals: exploratory research of consumer preference toward solid oral dosage forms.

PubMed

Reisenwitz, T H; Wimbish, G J

1996-01-01

The capsule dosage form in nonprescription pharmaceuticals persists as being one of the most vulnerable to product tampering. This study examines consumer preference toward three solid oral dosage forms (capsules, caplets, and tablets) in nonprescription products. Thirteen independent variables representing dosage form attributes are measured on semantic differential scales. The data are analyzed using analysis of variance (ANOVA) and factor analysis. Implications for the pharmaceutical marketer are noted. Future directions for research are also outlined.

A Joint Investigation of Semantic Facilitation and Semantic Interference in Continuous Naming

ERIC Educational Resources Information Center

Scaltritti, Michele; Peressotti, Francesca; Navarrete, Eduardo

2017-01-01

When speakers name multiple semantically related items, opposing effects can be found. Semantic facilitation is found when naming 2 semantically related items in a row. In contrast, semantic interference is found when speakers name semantically related items separated by 1 or more intervening unrelated items. This latter form of interference is…

Testing the attentional boundary conditions of subliminal semantic priming: the influence of semantic and phonological task sets

PubMed Central

Adams, Sarah C.; Kiefer, Markus

2012-01-01

Recent studies challenged the classical notion of automaticity and indicated that even unconscious automatic semantic processing is under attentional control to some extent. In line with our attentional sensitization model, these data suggest that a sensitization of semantic pathways by a semantic task set is necessary for subliminal semantic priming to occur while non-semantic task sets attenuate priming. In the present study, we tested whether masked semantic priming is also reduced by phonological task sets using the previously developed induction task paradigm. This would substantiate the notion that attention to semantics is necessary for eliciting unconscious semantic priming. Participants first performed semantic and phonological induction tasks that should either activate a semantic or a phonological task set. Subsequent to the induction task, a masked prime word, either associated or non-associated with the following lexical decision target word, was presented. Across two experiments, we varied the nature of the phonological induction task (word phonology vs. letter phonology) to assess whether the attentional focus on the entire word vs. single letters modulates subsequent masked semantic priming. In both experiments, subliminal semantic priming was only found subsequent to the semantic induction task, but was attenuated following either phonological induction task. These results indicate that attention to phonology attenuates subsequent semantic processing of unconsciously presented primes whether or not attention is directed to the entire word or to single letters. The present findings therefore substantiate earlier evidence that an attentional orientation toward semantics is necessary for subliminal semantic priming to be elicited. PMID:22952461

Getting connected: Both associative and semantic links structure semantic memory for newly learned persons.

PubMed

Wiese, Holger; Schweinberger, Stefan R

2015-01-01

The present study examined whether semantic memory for newly learned people is structured by visual co-occurrence, shared semantics, or both. Participants were trained with pairs of simultaneously presented (i.e., co-occurring) preexperimentally unfamiliar faces, which either did or did not share additionally provided semantic information (occupation, place of living, etc.). Semantic information could also be shared between faces that did not co-occur. A subsequent priming experiment revealed faster responses for both co-occurrence/no shared semantics and no co-occurrence/shared semantics conditions, than for an unrelated condition. Strikingly, priming was strongest in the co-occurrence/shared semantics condition, suggesting additive effects of these factors. Additional analysis of event-related brain potentials yielded priming in the N400 component only for combined effects of visual co-occurrence and shared semantics, with more positive amplitudes in this than in the unrelated condition. Overall, these findings suggest that both semantic relatedness and visual co-occurrence are important when novel information is integrated into person-related semantic memory.

A pool of pairs of related objects (POPORO) for investigating visual semantic integration: behavioral and electrophysiological validation.

PubMed

Kovalenko, Lyudmyla Y; Chaumon, Maximilien; Busch, Niko A

2012-07-01

Semantic processing of verbal and visual stimuli has been investigated in semantic violation or semantic priming paradigms in which a stimulus is either related or unrelated to a previously established semantic context. A hallmark of semantic priming is the N400 event-related potential (ERP)--a deflection of the ERP that is more negative for semantically unrelated target stimuli. The majority of studies investigating the N400 and semantic integration have used verbal material (words or sentences), and standardized stimulus sets with norms for semantic relatedness have been published for verbal but not for visual material. However, semantic processing of visual objects (as opposed to words) is an important issue in research on visual cognition. In this study, we present a set of 800 pairs of semantically related and unrelated visual objects. The images were rated for semantic relatedness by a sample of 132 participants. Furthermore, we analyzed low-level image properties and matched the two semantic categories according to these features. An ERP study confirmed the suitability of this image set for evoking a robust N400 effect of semantic integration. Additionally, using a general linear modeling approach of single-trial data, we also demonstrate that low-level visual image properties and semantic relatedness are in fact only minimally overlapping. The image set is available for download from the authors' website. We expect that the image set will facilitate studies investigating mechanisms of semantic and contextual processing of visual stimuli.

A Semantic Analysis Method for Scientific and Engineering Code

NASA Technical Reports Server (NTRS)

Stewart, Mark E. M.

1998-01-01

This paper develops a procedure to statically analyze aspects of the meaning or semantics of scientific and engineering code. The analysis involves adding semantic declarations to a user's code and parsing this semantic knowledge with the original code using multiple expert parsers. These semantic parsers are designed to recognize formulae in different disciplines including physical and mathematical formulae and geometrical position in a numerical scheme. In practice, a user would submit code with semantic declarations of primitive variables to the analysis procedure, and its semantic parsers would automatically recognize and document some static, semantic concepts and locate some program semantic errors. A prototype implementation of this analysis procedure is demonstrated. Further, the relationship between the fundamental algebraic manipulations of equations and the parsing of expressions is explained. This ability to locate some semantic errors and document semantic concepts in scientific and engineering code should reduce the time, risk, and effort of developing and using these codes.

The Role of Simple Semantics in the Process of Artificial Grammar Learning.

PubMed

Öttl, Birgit; Jäger, Gerhard; Kaup, Barbara

2017-10-01

This study investigated the effect of semantic information on artificial grammar learning (AGL). Recursive grammars of different complexity levels (regular language, mirror language, copy language) were investigated in a series of AGL experiments. In the with-semantics condition, participants acquired semantic information prior to the AGL experiment; in the without-semantics control condition, participants did not receive semantic information. It was hypothesized that semantics would generally facilitate grammar acquisition and that the learning benefit in the with-semantics conditions would increase with increasing grammar complexity. Experiment 1 showed learning effects for all grammars but no performance difference between conditions. Experiment 2 replicated the absence of a semantic benefit for all grammars even though semantic information was more prominent during grammar acquisition as compared to Experiment 1. Thus, we did not find evidence for the idea that semantics facilitates grammar acquisition, which seems to support the view of an independent syntactic processing component.

Lexical-semantic processing in the semantic priming paradigm in aphasic patients.

PubMed

Salles, Jerusa Fumagalli de; Holderbaum, Candice Steffen; Parente, Maria Alice Mattos Pimenta; Mansur, Letícia Lessa; Ansaldo, Ana Inès

2012-09-01

There is evidence that the explicit lexical-semantic processing deficits which characterize aphasia may be observed in the absence of implicit semantic impairment. The aim of this article was to critically review the international literature on lexical-semantic processing in aphasia, as tested through the semantic priming paradigm. Specifically, this review focused on aphasia and lexical-semantic processing, the methodological strengths and weaknesses of the semantic paradigms used, and recent evidence from neuroimaging studies on lexical-semantic processing. Furthermore, evidence on dissociations between implicit and explicit lexical-semantic processing reported in the literature will be discussed and interpreted by referring to functional neuroimaging evidence from healthy populations. There is evidence that semantic priming effects can be found both in fluent and in non-fluent aphasias, and that these effects are related to an extensive network which includes the temporal lobe, the pre-frontal cortex, the left frontal gyrus, the left temporal gyrus and the cingulated cortex.

Semantic Networks and Social Networks

ERIC Educational Resources Information Center

Downes, Stephen

2005-01-01

Purpose: To illustrate the need for social network metadata within semantic metadata. Design/methodology/approach: Surveys properties of social networks and the semantic web, suggests that social network analysis applies to semantic content, argues that semantic content is more searchable if social network metadata is merged with semantic web…

An individual differences approach to semantic cognition: Divergent effects of age on representation, retrieval and selection.

PubMed

Hoffman, Paul

2018-05-25

Semantic cognition refers to the appropriate use of acquired knowledge about the world. This requires representation of knowledge as well as control processes which ensure that currently-relevant aspects of knowledge are retrieved and selected. Although these abilities can be impaired selectively following brain damage, the relationship between them in healthy individuals is unclear. It is also commonly assumed that semantic cognition is preserved in later life, because older people have greater reserves of knowledge. However, this claim overlooks the possibility of decline in semantic control processes. Here, semantic cognition was assessed in 100 young and older adults. Despite having a broader knowledge base, older people showed specific impairments in semantic control, performing more poorly than young people when selecting among competing semantic representations. Conversely, they showed preserved controlled retrieval of less salient information from the semantic store. Breadth of semantic knowledge was positively correlated with controlled retrieval but was unrelated to semantic selection ability, which was instead correlated with non-semantic executive function. These findings indicate that three distinct elements contribute to semantic cognition: semantic representations that accumulate throughout the lifespan, processes for controlled retrieval of less salient semantic information, which appear age-invariant, and mechanisms for selecting task-relevant aspects of semantic knowledge, which decline with age and may relate more closely to domain-general executive control.

Individual perception of bees: Between perceived danger and willingness to protect

PubMed Central

Bogner, Franz Xaver

2017-01-01

The current loss of biodiversity has found its way into the media. Especially the loss of bees as pollinators has recently received much attention aiming to increase public awareness about the consequence of pollinator loss and strategies for protection. However, pollinating insects like bees often prompt considerable anxiety. Negative emotions such as fear and disgust often lead to lack of support for conservation and appropriate initiatives for protection. Our study monitored perceptions of bees in the contexts of conservation and danger bees possibly represent by applying a semantic differential using contrasting adjectives under the heading “I think bees are…”. Additionally, open questions were applied to examine individual perceptions of danger and conservation of bees. Respondents were students from primary school, secondary school and university. We compared these novices (n = 499) to experts (beekeepers, n = 153). An exploratory factor analysis of the semantic differential responses yielded three major oblique factors: Interest, Danger and Conservation & Usefulness. The inter-correlations of these factors were significant. Although all subgroups showed an overall high willingness to protect bees, the perception of danger scored medium. The individual experience of bee stings was the most prevalent reason for expressing fear. Educational programs focusing on pollinator conservation may reduce the perceived danger through removing misinformation, and supporting interest in the species. Based on the overall positive attitude toward bees, we suggest introducing bees (e.g., Apis mellifera) as a flagship species for pollinator conservation. PMID:28662124

A biopsychosocial investigation of changes in self-concept on the Head Injury Semantic Differential Scale.

PubMed

Reddy, Avneel; Ownsworth, Tamara; King, Joshua; Shields, Cassandra

2017-12-01

This study aimed to investigate the influence of the "good-old-days" bias, neuropsychological functioning and cued recall of life events on self-concept change. Forty seven adults with TBI (70% male, 1-5 years post-injury) and 47 matched controls rated their past and present self-concept on the Head Injury Semantic Differential Scale (HISD) III. TBI participants also completed a battery of neuropsychological tests. The matched control group of 47 were from a sample of 78 uninjured participants who were randomised to complete either the Social Readjustment Rating Scale-Revised (cued recall) or HISD (non-cued recall) first. Consistent with the good-old-days bias, participants with TBI rated their pre-injury self-concept as more positive than their present self-concept and the present self-concept of controls (p < .05). More positive pre-injury self-concept ratings were related to lower estimated premorbid IQ and poorer verbal fluency and delayed memory (p < .05). For uninjured participants, cued recall, life events and event appraisals each accounted for unique variance in self-concept change (p < .01) after controlling for negative affect. The cued recall group rated their past self-concept as significantly more negative than the non-cued group (p < .01). Overall, the good-old-days bias, neuropsychological functioning and cued recall influenced reports of self-concept change by affecting retrospective ratings of past self-concept. Further research is needed to investigate the impact of contextual cues on self-concept change after TBI.

Basic Sciences Fertilizing Clinical Microbiology and Infection Management

PubMed Central

2017-01-01

Abstract Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of “practice deconstruction” might reveal basic questions, as in de-differentiation of tissue cells. Basic sciences, microbiology, infectious diseases, and public health constitute an epistemological gradient that should also be an investigational continuum. The coexistence of all these interests and their cross-fertilization should be favored by interdisciplinary, integrative research organizations working simultaneously in the analytical and synthetic dimensions of scientific knowledge. PMID:28859345

Semantics, Pragmatics, and the Nature of Semantic Theories

ERIC Educational Resources Information Center

Spewak, David Charles, Jr.

2013-01-01

The primary concern of this dissertation is determining the distinction between semantics and pragmatics and how context sensitivity should be accommodated within a semantic theory. I approach the question over how to distinguish semantics from pragmatics from a new angle by investigating what the objects of a semantic theory are, namely…

Modulation of task demands suggests that semantic processing interferes with the formation of episodic associations

PubMed Central

Long, Nicole M.; Kahana, Michael J.

2016-01-01

Although episodic and semantic memory share overlapping neural mechanisms, it remains unclear how our pre-existing semantic associations modulate the formation of new, episodic associations. When freely recalling recently studied words, people rely on both episodic and semantic associations, shown through temporal and semantic clustering of responses. We asked whether orienting participants toward semantic associations interferes with or facilitates the formation of episodic associations. We compared electroencephalographic (EEG) activity recorded during the encoding of subsequently recalled words that were either temporally or semantically clustered. Participants studied words with or without a concurrent semantic orienting task. We identified a neural signature of successful episodic association formation whereby high frequency EEG activity (HFA, 44 – 100 Hz) overlying left prefrontal regions increased for subsequently temporally clustered words, but only for those words studied without a concurrent semantic orienting task. To confirm that this disruption in the formation of episodic associations was driven by increased semantic processing, we measured the neural correlates of subsequent semantic clustering. We found that HFA increased for subsequently semantically clustered words only for lists with a concurrent semantic orienting task. This dissociation suggests that increased semantic processing of studied items interferes with the neural processes that support the formation of novel episodic associations. PMID:27617775

Modulation of task demands suggests that semantic processing interferes with the formation of episodic associations.

PubMed

Long, Nicole M; Kahana, Michael J

2017-02-01

Although episodic and semantic memory share overlapping neural mechanisms, it remains unclear how our pre-existing semantic associations modulate the formation of new, episodic associations. When freely recalling recently studied words, people rely on both episodic and semantic associations, shown through temporal and semantic clustering of responses. We asked whether orienting participants toward semantic associations interferes with or facilitates the formation of episodic associations. We compared electroencephalographic (EEG) activity recorded during the encoding of subsequently recalled words that were either temporally or semantically clustered. Participants studied words with or without a concurrent semantic orienting task. We identified a neural signature of successful episodic association formation whereby high-frequency EEG activity (HFA, 44-100 Hz) overlying left prefrontal regions increased for subsequently temporally clustered words, but only for those words studied without a concurrent semantic orienting task. To confirm that this disruption in the formation of episodic associations was driven by increased semantic processing, we measured the neural correlates of subsequent semantic clustering. We found that HFA increased for subsequently semantically clustered words only for lists with a concurrent semantic orienting task. This dissociation suggests that increased semantic processing of studied items interferes with the neural processes that support the formation of novel episodic associations. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Semantic memory in object use.

PubMed

Silveri, Maria Caterina; Ciccarelli, Nicoletta

2009-10-01

We studied five patients with semantic memory disorders, four with semantic dementia and one with herpes simplex virus encephalitis, to investigate the involvement of semantic conceptual knowledge in object use. Comparisons between patients who had semantic deficits of different severity, as well as the follow-up, showed that the ability to use objects was largely preserved when the deficit was mild but progressively decayed as the deficit became more severe. Naming was generally more impaired than object use. Production tasks (pantomime execution and actual object use) and comprehension tasks (pantomime recognition and action recognition) as well as functional knowledge about objects were impaired when the semantic deficit was severe. Semantic and unrelated errors were produced during object use, but actions were always fluent and patients performed normally on a novel tools task in which the semantic demand was minimal. Patients with severe semantic deficits scored borderline on ideational apraxia tasks. Our data indicate that functional semantic knowledge is crucial for using objects in a conventional way and suggest that non-semantic factors, mainly non-declarative components of memory, might compensate to some extent for semantic disorders and guarantee some residual ability to use very common objects independently of semantic knowledge.

Semantic memory is impaired in patients with unilateral anterior temporal lobe resection for temporal lobe epilepsy.

PubMed

Lambon Ralph, Matthew A; Ehsan, Sheeba; Baker, Gus A; Rogers, Timothy T

2012-01-01

Contemporary clinical and basic neuroscience studies have increasingly implicated the anterior temporal lobe regions, bilaterally, in the formation of coherent concepts. Mounting convergent evidence for the importance of the anterior temporal lobe in semantic memory is found in patients with bilateral anterior temporal lobe damage (e.g. semantic dementia), functional neuroimaging and repetitive transcranial magnetic stimulation studies. If this proposal is correct, then one might expect patients with anterior temporal lobe resection for long-standing temporal lobe epilepsy to be semantically impaired. Such patients, however, do not present clinically with striking comprehension deficits but with amnesia and variable anomia, leading some to conclude that semantic memory is intact in resection for temporal lobe epilepsy and thus casting doubt over the conclusions drawn from semantic dementia and linked basic neuroscience studies. Whilst there is a considerable neuropsychological literature on temporal lobe epilepsy, few studies have probed semantic memory directly, with mixed results, and none have undertaken the same type of systematic investigation of semantic processing that has been conducted with other patient groups. In this study, therefore, we investigated the semantic performance of 20 patients with resection for chronic temporal lobe epilepsy with a full battery of semantic assessments, including more sensitive measures of semantic processing. The results provide a bridge between the current clinical observations about resection for temporal lobe epilepsy and the expectations from semantic dementia and other neuroscience findings. Specifically, we found that on simple semantic tasks, the patients' accuracy fell in the normal range, with the exception that some patients with left resection for temporal lobe epilepsy had measurable anomia. Once the semantic assessments were made more challenging, by probing specific-level concepts, lower frequency/more abstract items or measuring reaction times on semantic tasks versus those on difficulty-matched non-semantic assessments, evidence of a semantic impairment was found in all individuals. We conclude by describing a unified, computationally inspired framework for capturing the variable degrees of semantic impairment found across different patient groups (semantic dementia, temporal lobe epilepsy, glioma and stroke) as well as semantic processing in neurologically intact participants.

Semantic memory is impaired in patients with unilateral anterior temporal lobe resection for temporal lobe epilepsy

PubMed Central

Ehsan, Sheeba; Baker, Gus A.; Rogers, Timothy T.

2012-01-01

Contemporary clinical and basic neuroscience studies have increasingly implicated the anterior temporal lobe regions, bilaterally, in the formation of coherent concepts. Mounting convergent evidence for the importance of the anterior temporal lobe in semantic memory is found in patients with bilateral anterior temporal lobe damage (e.g. semantic dementia), functional neuroimaging and repetitive transcranial magnetic stimulation studies. If this proposal is correct, then one might expect patients with anterior temporal lobe resection for long-standing temporal lobe epilepsy to be semantically impaired. Such patients, however, do not present clinically with striking comprehension deficits but with amnesia and variable anomia, leading some to conclude that semantic memory is intact in resection for temporal lobe epilepsy and thus casting doubt over the conclusions drawn from semantic dementia and linked basic neuroscience studies. Whilst there is a considerable neuropsychological literature on temporal lobe epilepsy, few studies have probed semantic memory directly, with mixed results, and none have undertaken the same type of systematic investigation of semantic processing that has been conducted with other patient groups. In this study, therefore, we investigated the semantic performance of 20 patients with resection for chronic temporal lobe epilepsy with a full battery of semantic assessments, including more sensitive measures of semantic processing. The results provide a bridge between the current clinical observations about resection for temporal lobe epilepsy and the expectations from semantic dementia and other neuroscience findings. Specifically, we found that on simple semantic tasks, the patients’ accuracy fell in the normal range, with the exception that some patients with left resection for temporal lobe epilepsy had measurable anomia. Once the semantic assessments were made more challenging, by probing specific-level concepts, lower frequency/more abstract items or measuring reaction times on semantic tasks versus those on difficulty-matched non-semantic assessments, evidence of a semantic impairment was found in all individuals. We conclude by describing a unified, computationally inspired framework for capturing the variable degrees of semantic impairment found across different patient groups (semantic dementia, temporal lobe epilepsy, glioma and stroke) as well as semantic processing in neurologically intact participants. PMID:22287382

Semantic control and modality: an input processing deficit in aphasia leading to deregulated semantic cognition in a single modality.

PubMed

Thompson, Hannah E; Jefferies, Elizabeth

2013-08-01

Research suggests that semantic memory deficits can occur in at least three ways. Patients can (1) show amodal degradation of concepts within the semantic store itself, such as in semantic dementia (SD), (2) have difficulty in controlling activation within the semantic system and accessing appropriate knowledge in line with current goals or context, as in semantic aphasia (SA) and (3) experience a semantic deficit in only one modality following degraded input from sensory cortex. Patients with SA show deficits of semantic control and access across word and picture tasks, consistent with the view that their problems arise from impaired modality-general control processes. However, there are a few reports in the literature of patients with semantic access problems restricted to auditory-verbal materials, who show decreasing ability to retrieve concepts from words when they are presented repeatedly with closely related distractors. These patients challenge the notion that semantic control processes are modality-general and suggest instead a separation of 'access' to auditory-verbal and non-verbal semantic systems. We had the rare opportunity to study such a case in detail. Our aims were to examine the effect of manipulations of control demands in auditory-verbal semantic, non-verbal semantic and non-semantic tasks, allowing us to assess whether such cases always show semantic control/access impairments that follow a modality-specific pattern, or whether there are alternative explanations. Our findings revealed: (1) deficits on executive tasks, unrelated to semantic demands, which were more evident in the auditory modality than the visual modality; (2) deficits in executively-demanding semantic tasks which were accentuated in the auditory-verbal domain compared with the visual modality, but still present on non-verbal tasks, and (3) a coupling between comprehension and executive control requirements, in that mild impairment on single word comprehension was greatly increased on more demanding, associative judgements across modalities. This pattern of results suggests that mild executive-semantic impairment, paired with disrupted connectivity from auditory input, may give rise to semantic 'access' deficits affecting only the auditory modality. Copyright © 2013 Elsevier Ltd. All rights reserved.

Selective Short-Term Memory Deficits Arise from Impaired Domain-General Semantic Control Mechanisms

ERIC Educational Resources Information Center

Hoffman, Paul; Jefferies, Elizabeth; Ehsan, Sheeba; Hopper, Samantha; Lambon Ralph, Matthew A.

2009-01-01

Semantic short-term memory (STM) patients have a reduced ability to retain semantic information over brief delays but perform well on other semantic tasks; this pattern suggests damage to a dedicated buffer for semantic information. Alternatively, these difficulties may arise from mild disruption to domain-general semantic processes that have…

Linguistic and Non-Linguistic Semantic Processing in Individuals with Autism Spectrum Disorders: An ERP Study.

PubMed

Coderre, Emily L; Chernenok, Mariya; Gordon, Barry; Ledoux, Kerry

2017-03-01

Individuals with autism spectrum disorders (ASD) experience difficulties with language, particularly higher-level functions like semantic integration. Yet some studies indicate that semantic processing of non-linguistic stimuli is not impaired, suggesting a language-specific deficit in semantic processing. Using a semantic priming task, we compared event-related potentials (ERPs) in response to lexico-semantic processing (written words) and visuo-semantic processing (pictures) in adults with ASD and adults with typical development (TD). The ASD group showed successful lexico-semantic and visuo-semantic processing, indicated by similar N400 effects between groups for word and picture stimuli. However, differences in N400 latency and topography in word conditions suggested different lexico-semantic processing mechanisms: an expectancy-based strategy for the TD group but a controlled post-lexical integration strategy for the ASD group.

Exploiting Recurring Structure in a Semantic Network

NASA Technical Reports Server (NTRS)

Wolfe, Shawn R.; Keller, Richard M.

2004-01-01

With the growing popularity of the Semantic Web, an increasing amount of information is becoming available in machine interpretable, semantically structured networks. Within these semantic networks are recurring structures that could be mined by existing or novel knowledge discovery methods. The mining of these semantic structures represents an interesting area that focuses on mining both for and from the Semantic Web, with surprising applicability to problems confronting the developers of Semantic Web applications. In this paper, we present representative examples of recurring structures and show how these structures could be used to increase the utility of a semantic repository deployed at NASA.

Introduction to geospatial semantics and technology workshop handbook

USGS Publications Warehouse

Varanka, Dalia E.

2012-01-01

The workshop is a tutorial on introductory geospatial semantics with hands-on exercises using standard Web browsers. The workshop is divided into two sections, general semantics on the Web and specific examples of geospatial semantics using data from The National Map of the U.S. Geological Survey and the Open Ontology Repository. The general semantics section includes information and access to publicly available semantic archives. The specific session includes information on geospatial semantics with access to semantically enhanced data for hydrography, transportation, boundaries, and names. The Open Ontology Repository offers open-source ontologies for public use.

Mimicking aphasic semantic errors in normal speech production: evidence from a novel experimental paradigm.

PubMed

Hodgson, Catherine; Lambon Ralph, Matthew A

2008-01-01

Semantic errors are commonly found in semantic dementia (SD) and some forms of stroke aphasia and provide insights into semantic processing and speech production. Low error rates are found in standard picture naming tasks in normal controls. In order to increase error rates and thus provide an experimental model of aphasic performance, this study utilised a novel method- tempo picture naming. Experiment 1 showed that, compared to standard deadline naming tasks, participants made more errors on the tempo picture naming tasks. Further, RTs were longer and more errors were produced to living items than non-living items a pattern seen in both semantic dementia and semantically-impaired stroke aphasic patients. Experiment 2 showed that providing the initial phoneme as a cue enhanced performance whereas providing an incorrect phonemic cue further reduced performance. These results support the contention that the tempo picture naming paradigm reduces the time allowed for controlled semantic processing causing increased error rates. This experimental procedure would, therefore, appear to mimic the performance of aphasic patients with multi-modal semantic impairment that results from poor semantic control rather than the degradation of semantic representations observed in semantic dementia [Jefferies, E. A., & Lambon Ralph, M. A. (2006). Semantic impairment in stoke aphasia vs. semantic dementia: A case-series comparison. Brain, 129, 2132-2147]. Further implications for theories of semantic cognition and models of speech processing are discussed.

Activation of semantic information at the sublexical level during handwriting production: Evidence from inhibition effects of Chinese semantic radicals in the picture-word interference paradigm.

PubMed

Chen, Xuqian; Liao, Yuanlan; Chen, Xianzhe

2017-08-01

Using a non-alphabetic language (e.g., Chinese), the present study tested a novel view that semantic information at the sublexical level should be activated during handwriting production. Over 80% of Chinese characters are phonograms, in which semantic radicals represent category information (e.g., 'chair,' 'peach,' 'orange' are related to plants) while phonetic radicals represent phonetic information (e.g., 'wolf,' 'brightness,' 'male,' are all pronounced /lang/). Under different semantic category conditions at the lexical level (semantically related in Experiment 1; semantically unrelated in Experiment 2), the orthographic relatedness and semantic relatedness of semantic radicals in the picture name and its distractor were manipulated under different SOAs (i.e., stimulus onset asynchrony, the interval between the onset of the picture and the onset of the interference word). Two questions were addressed: (1) Is it possible that semantic information could be activated in the sublexical level conditions? (2) How are semantic and orthographic information dynamically accessed in word production? Results showed that both orthographic and semantic information were activated under the present picture-word interference paradigm, dynamically under different SOAs, which supported our view that discussions on semantic processes in the writing modality should be extended to the sublexical level. The current findings provide possibility for building new orthography-phonology-semantics models in writing. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Semantic encoding and retrieval in the left inferior prefrontal cortex: a functional MRI study of task difficulty and process specificity.

PubMed

Demb, J B; Desmond, J E; Wagner, A D; Vaidya, C J; Glover, G H; Gabrieli, J D

1995-09-01

Prefrontal cortical function was examined during semantic encoding and repetition priming using functional magnetic resonance imaging (fMRI), a noninvasive technique for localizing regional changes in blood oxygenation, a correlate of neural activity. Words studied in a semantic (deep) encoding condition were better remembered than words studied in both easier and more difficult nonsemantic (shallow) encoding conditions, with difficulty indexed by response time. The left inferior prefrontal cortex (LIPC) (Brodmann's areas 45, 46, 47) showed increased activation during semantic encoding relative to nonsemantic encoding regardless of the relative difficulty of the nonsemantic encoding task. Therefore, LIPC activation appears to be related to semantic encoding and not task difficulty. Semantic encoding decisions are performed faster the second time words are presented. This represents semantic repetition priming, a facilitation in semantic processing for previously encoded words that is not dependent on intentional recollection. The same LIPC area activated during semantic encoding showed decreased activation during repeated semantic encoding relative to initial semantic encoding of the same words. This decrease in activation during repeated encoding was process specific; it occurred when words were semantically reprocessed but not when words were nonsemantically reprocessed. The results were apparent in both individual and averaged functional maps. These findings suggest that the LIPC is part of a semantic executive system that contributes to the on-line retrieval of semantic information.

Cognitive correlates of verbal memory and verbal fluency in schizophrenia, and differential effects of various clinical symptoms between male and female patients.

PubMed

Brébion, Gildas; Villalta-Gil, Victoria; Autonell, Jaume; Cervilla, Jorge; Dolz, Montserrat; Foix, Alexandrina; Haro, Josep Maria; Usall, Judith; Vilaplana, Miriam; Ochoa, Susana

2013-06-01

Impairment of higher cognitive functions in patients with schizophrenia might stem from perturbation of more basic functions, such as processing speed. Various clinical symptoms might affect cognitive efficiency as well. Notably, previous research has revealed the role of affective symptoms on memory performance in this population, and suggested sex-specific effects. We conducted a post-hoc analysis of an extensive neuropsychological study of 88 patients with schizophrenia. Regression analyses were conducted on verbal memory and verbal fluency data to investigate the contribution of semantic organisation and processing speed to performance. The role of negative and affective symptoms and of attention disorders in verbal memory and verbal fluency was investigated separately in male and female patients. Semantic clustering contributed to verbal recall, and a measure of reading speed contributed to verbal recall as well as to phonological and semantic fluency. Negative symptoms affected verbal recall and verbal fluency in the male patients, whereas attention disorders affected these abilities in the female patients. Furthermore, depression affected verbal recall in women, whereas anxiety affected it in men. These results confirm the association of processing speed with cognitive efficiency in patients with schizophrenia. They also confirm the previously observed sex-specific associations of depression and anxiety with memory performance in these patients, and suggest that negative symptoms and attention disorders likewise are related to cognitive efficiency differently in men and women. Copyright © 2013 Elsevier B.V. All rights reserved.

Creative constraints: Brain activity and network dynamics underlying semantic interference during idea production.

PubMed

Beaty, Roger E; Christensen, Alexander P; Benedek, Mathias; Silvia, Paul J; Schacter, Daniel L

2017-03-01

Functional neuroimaging research has recently revealed brain network interactions during performance on creative thinking tasks-particularly among regions of the default and executive control networks-but the cognitive mechanisms related to these interactions remain poorly understood. Here we test the hypothesis that the executive control network can interact with the default network to inhibit salient conceptual knowledge (i.e., pre-potent responses) elicited from memory during creative idea production. Participants studied common noun-verb pairs and were given a cued-recall test with corrective feedback to strengthen the paired association in memory. They then completed a verb generation task that presented either a previously studied noun (high-constraint) or an unstudied noun (low-constraint), and were asked to "think creatively" while searching for a novel verb to relate to the presented noun. Latent Semantic Analysis of verbal responses showed decreased semantic distance values in the high-constraint (i.e., interference) condition, which corresponded to increased neural activity within regions of the default (posterior cingulate cortex and bilateral angular gyri), salience (right anterior insula), and executive control (left dorsolateral prefrontal cortex) networks. Independent component analysis of intrinsic functional connectivity networks extended this finding by revealing differential interactions among these large-scale networks across the task conditions. The results suggest that interactions between the default and executive control networks underlie response inhibition during constrained idea production, providing insight into specific neurocognitive mechanisms supporting creative cognition. Copyright © 2017 Elsevier Inc. All rights reserved.

The emotion potential of words and passages in reading Harry Potter--an fMRI study.

PubMed

Hsu, Chun-Ting; Jacobs, Arthur M; Citron, Francesca M M; Conrad, Markus

2015-03-01

Previous studies suggested that the emotional connotation of single words automatically recruits attention. We investigated the potential of words to induce emotional engagement when reading texts. In an fMRI experiment, we presented 120 text passages from the Harry Potter book series. Results showed significant correlations between affective word (lexical) ratings and passage ratings. Furthermore, affective lexical ratings correlated with activity in regions associated with emotion, situation model building, multi-modal semantic integration, and Theory of Mind. We distinguished differential influences of affective lexical, inter-lexical, and supra-lexical variables: differential effects of lexical valence were significant in the left amygdala, while effects of arousal-span (the dynamic range of arousal across a passage) were significant in the left amygdala and insula. However, we found no differential effect of passage ratings in emotion-associated regions. Our results support the hypothesis that the emotion potential of short texts can be predicted by lexical and inter-lexical affective variables. Copyright © 2015 Elsevier Inc. All rights reserved.

Evidence of semantic processing impairments in behavioural variant frontotemporal dementia and Parkinson's disease.

PubMed

Cousins, Katheryn A Q; Grossman, Murray

2017-12-01

Category-specific impairments caused by brain damage can provide important insights into how semantic concepts are organized in the brain. Recent research has demonstrated that disease to sensory and motor cortices can impair perceptual feature knowledge important to the representation of semantic concepts. This evidence supports the grounded cognition theory of semantics, the view that lexical knowledge is partially grounded in perceptual experience and that sensory and motor regions support semantic representations. Less well understood, however, is how heteromodal semantic hubs work to integrate and process semantic information. Although the majority of semantic research to date has focused on how sensory cortical areas are important for the representation of semantic features, new research explores how semantic memory is affected by neurodegeneration in regions important for semantic processing. Here, we review studies that demonstrate impairments to abstract noun knowledge in behavioural variant frontotemporal degeneration (bvFTD) and to action verb knowledge in Parkinson's disease, and discuss how these deficits relate to disease of the semantic selection network. Findings demonstrate that semantic selection processes are supported by the left inferior frontal gyrus (LIFG) and basal ganglia, and that disease to these regions in bvFTD and Parkinson's disease can lead to categorical impairments for abstract nouns and action verbs, respectively.

Type-specific proactive interference in patients with semantic and phonological STM deficits.

PubMed

Harris, Lara; Olson, Andrew; Humphreys, Glyn

2014-01-01

Prior neuropsychological evidence suggests that semantic and phonological components of short-term memory (STM) are functionally and neurologically distinct. The current paper examines proactive interference (PI) from semantic and phonological information in two STM-impaired patients, DS (semantic STM deficit) and AK (phonological STM deficit). In Experiment 1 probe recognition tasks with open and closed sets of stimuli were used. Phonological PI was assessed using nonword items, and semantic and phonological PI was assessed using words. In Experiment 2 phonological and semantic PI was elicited by an item recognition probe test with stimuli that bore phonological and semantic relations to the probes. The data suggested heightened phonological PI for the semantic STM patient, and exaggerated effects of semantic PI in the phonological STM case. The findings are consistent with an account of extremely rapid decay of activated type-specific representations in cases of severely impaired phonological and semantic STM.

Integrated Japanese Dependency Analysis Using a Dialog Context

NASA Astrophysics Data System (ADS)

Ikegaya, Yuki; Noguchi, Yasuhiro; Kogure, Satoru; Itoh, Toshihiko; Konishi, Tatsuhiro; Kondo, Makoto; Asoh, Hideki; Takagi, Akira; Itoh, Yukihiro

This paper describes how to perform syntactic parsing and semantic analysis in a dialog system. The paper especially deals with how to disambiguate potentially ambiguous sentences using the contextual information. Although syntactic parsing and semantic analysis are often studied independently of each other, correct parsing of a sentence often requires the semantic information on the input and/or the contextual information prior to the input. Accordingly, we merge syntactic parsing with semantic analysis, which enables syntactic parsing taking advantage of the semantic content of an input and its context. One of the biggest problems of semantic analysis is how to interpret dependency structures. We employ a framework for semantic representations that circumvents the problem. Within the framework, the meaning of any predicate is converted into a semantic representation which only permits a single type of predicate: an identifying predicate "aru". The semantic representations are expressed as sets of "attribute-value" pairs, and those semantic representations are stored in the context information. Our system disambiguates syntactic/semantic ambiguities of inputs referring to the attribute-value pairs in the context information. We have experimentally confirmed the effectiveness of our approach; specifically, the experiment confirmed high accuracy of parsing and correctness of generated semantic representations.

Observer Bias: An Interaction of Temperament Traits with Biases in the Semantic Perception of Lexical Material

PubMed Central

Trofimova, Ira

2014-01-01

The lexical approach is a method in differential psychology that uses people's estimations of verbal descriptors of human behavior in order to derive the structure of human individuality. The validity of the assumptions of this method about the objectivity of people's estimations is rarely questioned. Meanwhile the social nature of language and the presence of emotionality biases in cognition are well-recognized in psychology. A question remains, however, as to whether such an emotionality-capacities bias is strong enough to affect semantic perception of verbal material. For the lexical approach to be valid as a method of scientific investigations, such biases should not exist in semantic perception of the verbal material that is used by this approach. This article reports on two studies investigating differences between groups contrasted by 12 temperament traits (i.e. by energetic and other capacities, as well as emotionality) in the semantic perception of very general verbal material. Both studies contrasted the groups by a variety of capacities: endurance, lability and emotionality separately in physical, social-verbal and mental aspects of activities. Hypotheses of “background emotionality” and a “projection through capacities” were supported. Non-evaluative criteria for categorization (related to complexity, organization, stability and probability of occurrence of objects) followed the polarity of evaluative criteria, and did not show independence from this polarity. Participants with stronger physical or social endurance gave significantly more positive ratings to a variety of concepts, and participants with faster physical tempo gave more positive ratings to timing-related concepts. The results suggest that people's estimations of lexical material related to human behavior have emotionality, language- and dynamical capacities-related biases and therefore are unreliable. This questions the validity of the lexical approach as a method for the objective study of stable individual differences. PMID:24475048

Knowledge Evolution in Distributed Geoscience Datasets and the Role of Semantic Technologies

NASA Astrophysics Data System (ADS)

Ma, X.

2014-12-01

Knowledge evolves in geoscience, and the evolution is reflected in datasets. In a context with distributed data sources, the evolution of knowledge may cause considerable challenges to data management and re-use. For example, a short news published in 2009 (Mascarelli, 2009) revealed the geoscience community's concern that the International Commission on Stratigraphy's change to the definition of Quaternary may bring heavy reworking of geologic maps. Now we are in the era of the World Wide Web, and geoscience knowledge is increasingly modeled and encoded in the form of ontologies and vocabularies by using semantic technologies. Accordingly, knowledge evolution leads to a consequence called ontology dynamics. Flouris et al. (2008) summarized 10 topics of general ontology changes/dynamics such as: ontology mapping, morphism, evolution, debugging and versioning, etc. Ontology dynamics makes impacts at several stages of a data life cycle and causes challenges, such as: the request for reworking of the extant data in a data center, semantic mismatch among data sources, differentiated understanding of a same piece of dataset between data providers and data users, as well as error propagation in cross-discipline data discovery and re-use (Ma et al., 2014). This presentation will analyze the best practices in the geoscience community so far and summarize a few recommendations to reduce the negative impacts of ontology dynamics in a data life cycle, including: communities of practice and collaboration on ontology and vocabulary building, link data records to standardized terms, and methods for (semi-)automatic reworking of datasets using semantic technologies. References: Flouris, G., Manakanatas, D., Kondylakis, H., Plexousakis, D., Antoniou, G., 2008. Ontology change: classification and survey. The Knowledge Engineering Review 23 (2), 117-152. Ma, X., Fox, P., Rozell, E., West, P., Zednik, S., 2014. Ontology dynamics in a data life cycle: Challenges and recommendations from a Geoscience Perspective. Journal of Earth Science 25 (2), 407-412. Mascarelli, A.L., 2009. Quaternary geologists win timescale vote. Nature 459, 624.

Explaining semantic short-term memory deficits: Evidence for the critical role of semantic control

PubMed Central

Hoffman, Paul; Jefferies, Elizabeth; Lambon Ralph, Matthew A.

2011-01-01

Patients with apparently selective short-term memory (STM) deficits for semantic information have played an important role in developing multi-store theories of STM and challenge the idea that verbal STM is supported by maintaining activation in the language system. We propose that semantic STM deficits are not as selective as previously thought and can occur as a result of mild disruption to semantic control processes, i.e., mechanisms that bias semantic processing towards task-relevant aspects of knowledge and away from irrelevant information. We tested three semantic STM patients with tasks that tapped four aspects of semantic control: (i) resolving ambiguity between word meanings, (ii) sensitivity to cues, (iii) ignoring irrelevant information and (iv) detecting weak semantic associations. All were impaired in conditions requiring more semantic control, irrespective of the STM demands of the task, suggesting a mild, but task-general, deficit in regulating semantic knowledge. This mild deficit has a disproportionate effect on STM tasks because they have high intrinsic control demands: in STM tasks, control is required to keep information active when it is no longer available in the environment and to manage competition between items held in memory simultaneously. By re-interpreting the core deficit in semantic STM patients in this way, we are able to explain their apparently selective impairment without the need for a specialised STM store. Instead, we argue that semantic STM patients occupy the mildest end of spectrum of semantic control disorders. PMID:21195105

[Schizophrenia and semantic priming effects].

PubMed

Lecardeur, L; Giffard, B; Eustache, F; Dollfus, S

2006-01-01

This article is a review of studies using the semantic priming paradigm to assess the functioning of semantic memory in schizophrenic patients. Semantic priming describes the phenomenon of increasing the speed with which a string of letters (the target) is recognized as a word (lexical decision task) by presenting to the subject a semantically related word (the prime) prior to the appearance of the target word. This semantic priming is linked to both automatic and controlled processes depending on experimental conditions (stimulus onset asynchrony (SOA), percentage of related words and explicit memory instructions). Automatic process observed with short SOA, low related word percentage and instructions asking only to process the target, could be linked to the "automatic spreading activation" through the semantic network. Controlled processes involve "semantic matching" (the number of related and unrelated pairs influences the subjects decision) and "expectancy" (the prime leads the subject to generate an expectancy set of potential target to the prime). These processes can be observed whatever the SOA for the former and with long SOA for the later, but both with only high related word percentage and explicit memory instructions. Studies evaluating semantic priming effects in schizophrenia show conflicting results: schizophrenic patients can present hyperpriming (semantic priming effect is larger in patients than in controls), hypopriming (semantic priming effect is lower in patients than in controls) or equal semantic priming effects compared to control subjects. These results could be associated to a global impairment of controlled processes in schizophrenia, essentially to a dysfunction of semantic matching process. On the other hand, efficiency of semantic automatic spreading activation process is controversial. These discrepancies could be linked to the different experimental conditions used (duration of SOA, proportion of related pairs and instructions), which influence on the degree of involvement of controlled processes and therefore prevent to really assess its functioning. In addition, manipulations of the relation between prime and target (semantic distance, type of semantic relation and strength of semantic relation) seem to influence reaction times. However, the relation between prime and target (mediated priming) frequently used could not be the most relevant relation to understand the way of spreading of activation in semantic network in patients with schizophrenia. Finally, patients with formal thought disorders present particularly high priming effects relative to controls. These abnormal semantic priming effects could reflect a dysfunction of automatic spreading activation process and consequently an exaggerated diffusion of activation in the semantic network. In the future, the inclusion of different groups schizophrenic subjects could allow us to determine whether semantic memory disorders are pathognomonic or specific of a particular group of patients with schizophrenia.

Wernicke's Aphasia Reflects a Combination of Acoustic-Phonological and Semantic Control Deficits: A Case-Series Comparison of Wernicke's Aphasia, Semantic Dementia and Semantic Aphasia

ERIC Educational Resources Information Center

Robson, Holly; Sage, Karen; Lambon Ralph, Matthew A.

2012-01-01

Wernicke's aphasia (WA) is the classical neurological model of comprehension impairment and, as a result, the posterior temporal lobe is assumed to be critical to semantic cognition. This conclusion is potentially confused by (a) the existence of patient groups with semantic impairment following damage to other brain regions (semantic dementia and…

Semantator: semantic annotator for converting biomedical text to linked data.

PubMed

Tao, Cui; Song, Dezhao; Sharma, Deepak; Chute, Christopher G

2013-10-01

More than 80% of biomedical data is embedded in plain text. The unstructured nature of these text-based documents makes it challenging to easily browse and query the data of interest in them. One approach to facilitate browsing and querying biomedical text is to convert the plain text to a linked web of data, i.e., converting data originally in free text to structured formats with defined meta-level semantics. In this paper, we introduce Semantator (Semantic Annotator), a semantic-web-based environment for annotating data of interest in biomedical documents, browsing and querying the annotated data, and interactively refining annotation results if needed. Through Semantator, information of interest can be either annotated manually or semi-automatically using plug-in information extraction tools. The annotated results will be stored in RDF and can be queried using the SPARQL query language. In addition, semantic reasoners can be directly applied to the annotated data for consistency checking and knowledge inference. Semantator has been released online and was used by the biomedical ontology community who provided positive feedbacks. Our evaluation results indicated that (1) Semantator can perform the annotation functionalities as designed; (2) Semantator can be adopted in real applications in clinical and transactional research; and (3) the annotated results using Semantator can be easily used in Semantic-web-based reasoning tools for further inference. Copyright © 2013 Elsevier Inc. All rights reserved.

The cognitive and neural expression of semantic memory impairment in mild cognitive impairment and early Alzheimer's disease.

PubMed

Joubert, Sven; Brambati, Simona M; Ansado, Jennyfer; Barbeau, Emmanuel J; Felician, Olivier; Didic, Mira; Lacombe, Jacinthe; Goldstein, Rachel; Chayer, Céline; Kergoat, Marie-Jeanne

2010-03-01

Semantic deficits in Alzheimer's disease have been widely documented, but little is known about the integrity of semantic memory in the prodromal stage of the illness. The aims of the present study were to: (i) investigate naming abilities and semantic memory in amnestic mild cognitive impairment (aMCI), early Alzheimer's disease (AD) compared to healthy older subjects; (ii) investigate the association between naming and semantic knowledge in aMCI and AD; (iii) examine if the semantic impairment was present in different modalities; and (iv) study the relationship between semantic performance and grey matter volume using voxel-based morphometry. Results indicate that both naming and semantic knowledge of objects and famous people were impaired in aMCI and early AD groups, when compared to healthy age- and education-matched controls. Item-by-item analyses showed that anomia in aMCI and early AD was significantly associated with underlying semantic knowledge of famous people but not with semantic knowledge of objects. Moreover, semantic knowledge of the same concepts was impaired in both the visual and the verbal modalities. Finally, voxel-based morphometry analyses revealed that semantic impairment in aMCI and AD was associated with cortical atrophy in the anterior temporal lobe (ATL) region as well as in the inferior prefrontal cortex (IPC), some of the key regions of the semantic cognition network. These findings suggest that the semantic impairment in aMCI may result from a breakdown of semantic knowledge of famous people and objects, combined with difficulties in the selection, manipulation and retrieval of this knowledge. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

Rule-based support system for multiple UMLS semantic type assignments

PubMed Central

Geller, James; He, Zhe; Perl, Yehoshua; Morrey, C. Paul; Xu, Julia

2012-01-01

Background When new concepts are inserted into the UMLS, they are assigned one or several semantic types from the UMLS Semantic Network by the UMLS editors. However, not every combination of semantic types is permissible. It was observed that many concepts with rare combinations of semantic types have erroneous semantic type assignments or prohibited combinations of semantic types. The correction of such errors is resource-intensive. Objective We design a computational system to inform UMLS editors as to whether a specific combination of two, three, four, or five semantic types is permissible or prohibited or questionable. Methods We identify a set of inclusion and exclusion instructions in the UMLS Semantic Network documentation and derive corresponding rule-categories as well as rule-categories from the UMLS concept content. We then design an algorithm adviseEditor based on these rule-categories. The algorithm specifies rules for an editor how to proceed when considering a tuple (pair, triple, quadruple, quintuple) of semantic types to be assigned to a concept. Results Eight rule-categories were identified. A Web-based system was developed to implement the adviseEditor algorithm, which returns for an input combination of semantic types whether it is permitted, prohibited or (in a few cases) requires more research. The numbers of semantic type pairs assigned to each rule-category are reported. Interesting examples for each rule-category are illustrated. Cases of semantic type assignments that contradict rules are listed, including recently introduced ones. Conclusion The adviseEditor system implements explicit and implicit knowledge available in the UMLS in a system that informs UMLS editors about the permissibility of a desired combination of semantic types. Using adviseEditor might help accelerate the work of the UMLS editors and prevent erroneous semantic type assignments. PMID:23041716

Word recognition in Alzheimer's disease: Effects of semantic degeneration.

PubMed

Cuetos, Fernando; Arce, Noemí; Martínez, Carmen; Ellis, Andrew W

2017-03-01

Impairments of word recognition in Alzheimer's disease (AD) have been less widely investigated than impairments affecting word retrieval and production. In particular, we know little about what makes individual words easier or harder for patients with AD to recognize. We used a lexical selection task in which participants were shown sets of four items, each set consisting of one word and three non-words. The task was simply to point to the word on each trial. Forty patients with mild-to-moderate AD were significantly impaired on this task relative to matched controls who made very few errors. The number of patients with AD able to recognize each word correctly was predicted by the frequency, age of acquisition, and imageability of the words, but not by their length or number of orthographic neighbours. Patient Mini-Mental State Examination and phonological fluency scores also predicted the number of words recognized. We propose that progressive degradation of central semantic representations in AD differentially affects the ability to recognize low-imageability, low-frequency, late-acquired words, with the same factors affecting word recognition as affecting word retrieval. © 2015 The British Psychological Society.

Integrating conceptual knowledge within and across representational modalities.

PubMed

McNorgan, Chris; Reid, Jackie; McRae, Ken

2011-02-01

Research suggests that concepts are distributed across brain regions specialized for processing information from different sensorimotor modalities. Multimodal semantic models fall into one of two broad classes differentiated by the assumed hierarchy of convergence zones over which information is integrated. In shallow models, communication within- and between-modality is accomplished using either direct connectivity, or a central semantic hub. In deep models, modalities are connected via cascading integration sites with successively wider receptive fields. Four experiments provide the first direct behavioral tests of these models using speeded tasks involving feature inference and concept activation. Shallow models predict no within-modal versus cross-modal difference in either task, whereas deep models predict a within-modal advantage for feature inference, but a cross-modal advantage for concept activation. Experiments 1 and 2 used relatedness judgments to tap participants' knowledge of relations for within- and cross-modal feature pairs. Experiments 3 and 4 used a dual-feature verification task. The pattern of decision latencies across Experiments 1-4 is consistent with a deep integration hierarchy. Copyright © 2010 Elsevier B.V. All rights reserved.

OntoPop: An Ontology Population System for the Semantic Web

NASA Astrophysics Data System (ADS)

Thongkrau, Theerayut; Lalitrojwong, Pattarachai

The development of ontology at the instance level requires the extraction of the terms defining the instances from various data sources. These instances then are linked to the concepts of the ontology, and relationships are created between these instances for the next step. However, before establishing links among data, ontology engineers must classify terms or instances from a web document into an ontology concept. The tool for help ontology engineer in this task is called ontology population. The present research is not suitable for ontology development applications, such as long time processing or analyzing large or noisy data sets. OntoPop system introduces a methodology to solve these problems, which comprises two parts. First, we select meaningful features from syntactic relations, which can produce more significant features than any other method. Second, we differentiate feature meaning and reduce noise based on latent semantic analysis. Experimental evaluation demonstrates that the OntoPop works well, significantly out-performing the accuracy of 49.64%, a learning accuracy of 76.93%, and executes time of 5.46 second/instance.

Neural correlates of cognitive dysfunction in Lewy body diseases and tauopathies: combined assessment with FDG-PET and the CERAD test battery.

PubMed

Hellwig, Sabine; Frings, Lars; Bormann, Tobias; Kreft, Annabelle; Amtage, Florian; Spehl, Timo S; Weiller, Cornelius; Tüscher, Oliver; Meyer, Philipp T

2013-11-01

We investigated disease-specific cognitive profiles and their neural correlates in Lewy-body diseases (LBD) and tauopathies by CERAD assessment and FDG-PET. Analyses revealed a significant interaction between reduced semantic fluency in tauopathies and impaired verbal learning in LBD. Semantic fluency discriminated between groups with high accuracy (83%). Compared to LBD, tauopathy patients showed bilateral hypometabolism of midbrain, thalamus, middle cingulate gyrus and supplementary motor/premotor cortex. In the reverse contrast, LBD patients exhibited bilateral hypometabolism in posterior parietal cortex, precuneus and inferior temporal gyrus extending into occipital and frontal cortices. In diagnosis-independent voxel-based analyses, verbal learning/memory correlated with left temporal and right parietal metabolism, while fluency was coupled to bilateral striatal and frontal metabolism. Naming correlated with left frontal metabolism and drawing with metabolism in bilateral temporal and left frontal regions. In line with disease-specific patterns of regional glucose metabolism, tauopathies and LBD show distinct cognitive profiles, which may assist clinical differentiation. Copyright © 2013 Elsevier Inc. All rights reserved.

Creative thinking as orchestrated by semantic processing vs. cognitive control brain networks

PubMed Central

Abraham, Anna

2014-01-01

Creativity is primarily investigated within the neuroscientific perspective as a unitary construct. While such an approach is beneficial when trying to infer the general picture regarding creativity and brain function, it is insufficient if the objective is to uncover the information processing brain mechanisms by which creativity occurs. As creative thinking emerges through the dynamic interplay between several cognitive processes, assessing the neural correlates of these operations would enable the development and characterization of an information processing framework from which to better understand this complex ability. This article focuses on two aspects of creative cognition that are central to generating original ideas. “Conceptual expansion” refers to the ability to widen one’s conceptual structures to include unusual or novel associations, while “overcoming knowledge constraints” refers to our ability to override the constraining influence imposed by salient or pertinent knowledge when trying to be creative. Neuroimaging and neuropsychological evidence is presented to illustrate how semantic processing and cognitive control networks in the brain differentially modulate these critical facets of creative cognition. PMID:24605098

An investigation of time course of category and semantic priming.

PubMed

Ray, Suchismita

2008-04-01

Low semantically similar exemplars in a category demonstrate the category-priming effect through priming of the category (i.e., exemplar-category-exemplar), whereas high semantically similar exemplars in the same category demonstrate the semantic-priming effect (i.e., direct activation of one high semantically similar exemplar by another). The author asked whether the category- and semantic-priming effects are based on a common memory process. She examined this question by testing the time courses of category- and semantic-priming effects. She tested participants on either category- or semantic-priming paradigm at 2 different time intervals (6 min and 42 min) by using a lexical decision task using exemplars from categories. Results showed that the time course of category priming was different from that of semantic priming. The author concludes that these 2 priming effects are based on 2 separate memory processes.

Varieties of semantic ‘access’ deficit in Wernicke’s aphasia and semantic aphasia

PubMed Central

Robson, Holly; Lambon Ralph, Matthew A.; Jefferies, Elizabeth

2015-01-01

Comprehension deficits are common in stroke aphasia, including in cases with (i) semantic aphasia, characterized by poor executive control of semantic processing across verbal and non-verbal modalities; and (ii) Wernicke’s aphasia, associated with poor auditory–verbal comprehension and repetition, plus fluent speech with jargon. However, the varieties of these comprehension problems, and their underlying causes, are not well understood. Both patient groups exhibit some type of semantic ‘access’ deficit, as opposed to the ‘storage’ deficits observed in semantic dementia. Nevertheless, existing descriptions suggest that these patients might have different varieties of ‘access’ impairment—related to difficulty resolving competition (in semantic aphasia) versus initial activation of concepts from sensory inputs (in Wernicke’s aphasia). We used a case series design to compare patients with Wernicke’s aphasia and those with semantic aphasia on Warrington’s paradigmatic assessment of semantic ‘access’ deficits. In these verbal and non-verbal matching tasks, a small set of semantically-related items are repeatedly presented over several cycles so that the target on one trial becomes a distractor on another (building up interference and eliciting semantic ‘blocking’ effects). Patients with Wernicke’s aphasia and semantic aphasia were distinguished according to lesion location in the temporal cortex, but in each group, some individuals had additional prefrontal damage. Both of these aspects of lesion variability—one that mapped onto classical ‘syndromes’ and one that did not—predicted aspects of the semantic ‘access’ deficit. Both semantic aphasia and Wernicke’s aphasia cases showed multimodal semantic impairment, although as expected, the Wernicke’s aphasia group showed greater deficits on auditory-verbal than picture judgements. Distribution of damage in the temporal lobe was crucial for predicting the initially ‘beneficial’ effects of stimulus repetition: cases with Wernicke’s aphasia showed initial improvement with repetition of words and pictures, while in semantic aphasia, semantic access was initially good but declined in the face of competition from previous targets. Prefrontal damage predicted the ‘harmful’ effects of repetition: the ability to reselect both word and picture targets in the face of mounting competition was linked to left prefrontal damage in both groups. Therefore, patients with semantic aphasia and Wernicke’s aphasia have partially distinct impairment of semantic ‘access’ but, across these syndromes, prefrontal lesions produce declining comprehension with repetition in both verbal and non-verbal tasks. PMID:26454668

Varieties of semantic 'access' deficit in Wernicke's aphasia and semantic aphasia.

PubMed

Thompson, Hannah E; Robson, Holly; Lambon Ralph, Matthew A; Jefferies, Elizabeth

2015-12-01

Comprehension deficits are common in stroke aphasia, including in cases with (i) semantic aphasia, characterized by poor executive control of semantic processing across verbal and non-verbal modalities; and (ii) Wernicke's aphasia, associated with poor auditory-verbal comprehension and repetition, plus fluent speech with jargon. However, the varieties of these comprehension problems, and their underlying causes, are not well understood. Both patient groups exhibit some type of semantic 'access' deficit, as opposed to the 'storage' deficits observed in semantic dementia. Nevertheless, existing descriptions suggest that these patients might have different varieties of 'access' impairment-related to difficulty resolving competition (in semantic aphasia) versus initial activation of concepts from sensory inputs (in Wernicke's aphasia). We used a case series design to compare patients with Wernicke's aphasia and those with semantic aphasia on Warrington's paradigmatic assessment of semantic 'access' deficits. In these verbal and non-verbal matching tasks, a small set of semantically-related items are repeatedly presented over several cycles so that the target on one trial becomes a distractor on another (building up interference and eliciting semantic 'blocking' effects). Patients with Wernicke's aphasia and semantic aphasia were distinguished according to lesion location in the temporal cortex, but in each group, some individuals had additional prefrontal damage. Both of these aspects of lesion variability-one that mapped onto classical 'syndromes' and one that did not-predicted aspects of the semantic 'access' deficit. Both semantic aphasia and Wernicke's aphasia cases showed multimodal semantic impairment, although as expected, the Wernicke's aphasia group showed greater deficits on auditory-verbal than picture judgements. Distribution of damage in the temporal lobe was crucial for predicting the initially 'beneficial' effects of stimulus repetition: cases with Wernicke's aphasia showed initial improvement with repetition of words and pictures, while in semantic aphasia, semantic access was initially good but declined in the face of competition from previous targets. Prefrontal damage predicted the 'harmful' effects of repetition: the ability to reselect both word and picture targets in the face of mounting competition was linked to left prefrontal damage in both groups. Therefore, patients with semantic aphasia and Wernicke's aphasia have partially distinct impairment of semantic 'access' but, across these syndromes, prefrontal lesions produce declining comprehension with repetition in both verbal and non-verbal tasks. © The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain.

Semantic-gap-oriented active learning for multilabel image annotation.

PubMed

Tang, Jinhui; Zha, Zheng-Jun; Tao, Dacheng; Chua, Tat-Seng

2012-04-01

User interaction is an effective way to handle the semantic gap problem in image annotation. To minimize user effort in the interactions, many active learning methods were proposed. These methods treat the semantic concepts individually or correlatively. However, they still neglect the key motivation of user feedback: to tackle the semantic gap. The size of the semantic gap of each concept is an important factor that affects the performance of user feedback. User should pay more efforts to the concepts with large semantic gaps, and vice versa. In this paper, we propose a semantic-gap-oriented active learning method, which incorporates the semantic gap measure into the information-minimization-based sample selection strategy. The basic learning model used in the active learning framework is an extended multilabel version of the sparse-graph-based semisupervised learning method that incorporates the semantic correlation. Extensive experiments conducted on two benchmark image data sets demonstrated the importance of bringing the semantic gap measure into the active learning process.

The semantic anatomical network: Evidence from healthy and brain-damaged patient populations.

PubMed

Fang, Yuxing; Han, Zaizhu; Zhong, Suyu; Gong, Gaolang; Song, Luping; Liu, Fangsong; Huang, Ruiwang; Du, Xiaoxia; Sun, Rong; Wang, Qiang; He, Yong; Bi, Yanchao

2015-09-01

Semantic processing is central to cognition and is supported by widely distributed gray matter (GM) regions and white matter (WM) tracts. The exact manner in which GM regions are anatomically connected to process semantics remains unknown. We mapped the semantic anatomical network (connectome) by conducting diffusion imaging tractography in 48 healthy participants across 90 GM "nodes," and correlating the integrity of each obtained WM edge and semantic performance across 80 brain-damaged patients. Fifty-three WM edges were obtained whose lower integrity associated with semantic deficits and together with their linked GM nodes constitute a semantic WM network. Graph analyses of this network revealed three structurally segregated modules that point to distinct semantic processing components and identified network hubs and connectors that are central in the communication across the subnetworks. Together, our results provide an anatomical framework of human semantic network, advancing the understanding of the structural substrates supporting semantic processing. © 2015 Wiley Periodicals, Inc.

Episodic representations support early semantic learning: evidence from midazolam induced amnesia.

PubMed

Merritt, Paul; Hirshman, Elliot; Zamani, Shane; Hsu, John; Berrigan, Michael

2006-07-01

Current controversy exists regarding the role of episodic representations in the formation of long-term semantic memories. Using the drug midazolam to induce temporary amnesia we tested participants' memories for newly learned facts in a semantic cue condition or an episodic and semantic cue condition. Following midazolam administration, memory performance was superior in the episodic and semantic condition, suggesting early semantic learning is supported by episodic representations.

Auditing the Assignments of Top-Level Semantic Types in the UMLS Semantic Network to UMLS Concepts

PubMed Central

He, Zhe; Perl, Yehoshua; Elhanan, Gai; Chen, Yan; Geller, James; Bian, Jiang

2018-01-01

The Unified Medical Language System (UMLS) is an important terminological system. By the policy of its curators, each concept of the UMLS should be assigned the most specific Semantic Types (STs) in the UMLS Semantic Network (SN). Hence, the Semantic Types of most UMLS concepts are assigned at or near the bottom (leaves) of the UMLS Semantic Network. While most ST assignments are correct, some errors do occur. Therefore, Quality Assurance efforts of UMLS curators for ST assignments should concentrate on automatically detected sets of UMLS concepts with higher error rates than random sets. In this paper, we investigate the assignments of top-level semantic types in the UMLS semantic network to concepts, identify potential erroneous assignments, define four categories of errors, and thus provide assistance to curators of the UMLS to avoid these assignments errors. Human experts analyzed samples of concepts assigned 10 of the top-level semantic types and categorized the erroneous ST assignments into these four logical categories. Two thirds of the concepts assigned these 10 top-level semantic types are erroneous. Our results demonstrate that reviewing top-level semantic type assignments to concepts provides an effective way for UMLS quality assurance, comparing to reviewing a random selection of semantic type assignments. PMID:29375930

Auditing the Assignments of Top-Level Semantic Types in the UMLS Semantic Network to UMLS Concepts.

PubMed

He, Zhe; Perl, Yehoshua; Elhanan, Gai; Chen, Yan; Geller, James; Bian, Jiang

2017-11-01

The Unified Medical Language System (UMLS) is an important terminological system. By the policy of its curators, each concept of the UMLS should be assigned the most specific Semantic Types (STs) in the UMLS Semantic Network (SN). Hence, the Semantic Types of most UMLS concepts are assigned at or near the bottom (leaves) of the UMLS Semantic Network. While most ST assignments are correct, some errors do occur. Therefore, Quality Assurance efforts of UMLS curators for ST assignments should concentrate on automatically detected sets of UMLS concepts with higher error rates than random sets. In this paper, we investigate the assignments of top-level semantic types in the UMLS semantic network to concepts, identify potential erroneous assignments, define four categories of errors, and thus provide assistance to curators of the UMLS to avoid these assignments errors. Human experts analyzed samples of concepts assigned 10 of the top-level semantic types and categorized the erroneous ST assignments into these four logical categories. Two thirds of the concepts assigned these 10 top-level semantic types are erroneous. Our results demonstrate that reviewing top-level semantic type assignments to concepts provides an effective way for UMLS quality assurance, comparing to reviewing a random selection of semantic type assignments.

Wernicke's aphasia reflects a combination of acoustic-phonological and semantic control deficits: a case-series comparison of Wernicke's aphasia, semantic dementia and semantic aphasia.

PubMed

Robson, Holly; Sage, Karen; Ralph, Matthew A Lambon

2012-01-01

Wernicke's aphasia (WA) is the classical neurological model of comprehension impairment and, as a result, the posterior temporal lobe is assumed to be critical to semantic cognition. This conclusion is potentially confused by (a) the existence of patient groups with semantic impairment following damage to other brain regions (semantic dementia and semantic aphasia) and (b) an ongoing debate about the underlying causes of comprehension impairment in WA. By directly comparing these three patient groups for the first time, we demonstrate that the comprehension impairment in Wernicke's aphasia is best accounted for by dual deficits in acoustic-phonological analysis (associated with pSTG) and semantic cognition (associated with pMTG and angular gyrus). The WA group were impaired on both nonverbal and verbal comprehension assessments consistent with a generalised semantic impairment. This semantic deficit was most similar in nature to that of the semantic aphasia group suggestive of a disruption to semantic control processes. In addition, only the WA group showed a strong effect of input modality on comprehension, with accuracy decreasing considerably as acoustic-phonological requirements increased. These results deviate from traditional accounts which emphasise a single impairment and, instead, implicate two deficits underlying the comprehension disorder in WA. Copyright © 2011 Elsevier Ltd. All rights reserved.

Different Loci of Semantic Interference in Picture Naming vs. Word-Picture Matching Tasks.

PubMed

Harvey, Denise Y; Schnur, Tatiana T

2016-01-01

Naming pictures and matching words to pictures belonging to the same semantic category impairs performance relative to when stimuli come from different semantic categories (i.e., semantic interference). Despite similar semantic interference phenomena in both picture naming and word-picture matching tasks, the locus of interference has been attributed to different levels of the language system - lexical in naming and semantic in word-picture matching. Although both tasks involve access to shared semantic representations, the extent to which interference originates and/or has its locus at a shared level remains unclear, as these effects are often investigated in isolation. We manipulated semantic context in cyclical picture naming and word-picture matching tasks, and tested whether factors tapping semantic-level (generalization of interference to novel category items) and lexical-level processes (interactions with lexical frequency) affected the magnitude of interference, while also assessing whether interference occurs at a shared processing level(s) (transfer of interference across tasks). We found that semantic interference in naming was sensitive to both semantic- and lexical-level processes (i.e., larger interference for novel vs. old and low- vs. high-frequency stimuli), consistent with a semantically mediated lexical locus. Interference in word-picture matching exhibited stable interference for old and novel stimuli and did not interact with lexical frequency. Further, interference transferred from word-picture matching to naming. Together, these experiments provide evidence to suggest that semantic interference in both tasks originates at a shared processing stage (presumably at the semantic level), but that it exerts its effect at different loci when naming pictures vs. matching words to pictures.

Different Loci of Semantic Interference in Picture Naming vs. Word-Picture Matching Tasks

PubMed Central

Harvey, Denise Y.; Schnur, Tatiana T.

2016-01-01

Naming pictures and matching words to pictures belonging to the same semantic category impairs performance relative to when stimuli come from different semantic categories (i.e., semantic interference). Despite similar semantic interference phenomena in both picture naming and word-picture matching tasks, the locus of interference has been attributed to different levels of the language system – lexical in naming and semantic in word-picture matching. Although both tasks involve access to shared semantic representations, the extent to which interference originates and/or has its locus at a shared level remains unclear, as these effects are often investigated in isolation. We manipulated semantic context in cyclical picture naming and word-picture matching tasks, and tested whether factors tapping semantic-level (generalization of interference to novel category items) and lexical-level processes (interactions with lexical frequency) affected the magnitude of interference, while also assessing whether interference occurs at a shared processing level(s) (transfer of interference across tasks). We found that semantic interference in naming was sensitive to both semantic- and lexical-level processes (i.e., larger interference for novel vs. old and low- vs. high-frequency stimuli), consistent with a semantically mediated lexical locus. Interference in word-picture matching exhibited stable interference for old and novel stimuli and did not interact with lexical frequency. Further, interference transferred from word-picture matching to naming. Together, these experiments provide evidence to suggest that semantic interference in both tasks originates at a shared processing stage (presumably at the semantic level), but that it exerts its effect at different loci when naming pictures vs. matching words to pictures. PMID:27242621

Semantic Typicality Effects in Acquired Dyslexia: Evidence for Semantic Impairment in Deep Dyslexia.

PubMed

Riley, Ellyn A; Thompson, Cynthia K

2010-06-01

BACKGROUND: Acquired deep dyslexia is characterized by impairment in grapheme-phoneme conversion and production of semantic errors in oral reading. Several theories have attempted to explain the production of semantic errors in deep dyslexia, some proposing that they arise from impairments in both grapheme-phoneme and lexical-semantic processing, and others proposing that such errors stem from a deficit in phonological production. Whereas both views have gained some acceptance, the limited evidence available does not clearly eliminate the possibility that semantic errors arise from a lexical-semantic input processing deficit. AIMS: To investigate semantic processing in deep dyslexia, this study examined the typicality effect in deep dyslexic individuals, phonological dyslexic individuals, and controls using an online category verification paradigm. This task requires explicit semantic access without speech production, focusing observation on semantic processing from written or spoken input. METHODS #ENTITYSTARTX00026; PROCEDURES: To examine the locus of semantic impairment, the task was administered in visual and auditory modalities with reaction time as the primary dependent measure. Nine controls, six phonological dyslexic participants, and five deep dyslexic participants completed the study. OUTCOMES #ENTITYSTARTX00026; RESULTS: Controls and phonological dyslexic participants demonstrated a typicality effect in both modalities, while deep dyslexic participants did not demonstrate a typicality effect in either modality. CONCLUSIONS: These findings suggest that deep dyslexia is associated with a semantic processing deficit. Although this does not rule out the possibility of concomitant deficits in other modules of lexical-semantic processing, this finding suggests a direction for treatment of deep dyslexia focused on semantic processing.

Lack of semantic priming effects in famous person recognition in Mild Cognitive Impairment.

PubMed

Brambati, Simona M; Peters, Frédéric; Belleville, Sylvie; Joubert, Sven

2012-04-01

Growing evidence indicates that individuals with Mild Cognitive Impairment (MCI) manifest semantic deficits that are often more severe for items that are characterized by a unique semantic and lexical association, such as famous people and famous buildings, than common concepts, such as objects. However, it is still controversial whether the semantic deficits observed in MCI are determined by a degradation of semantic information or by a deficit in intentional access to semantic knowledge. Here we used a semantic priming task in order to assess the integrity of the semantic system without requiring explicit access to this system. This paradigm may provide new insights in clarifying the nature of the semantic deficits in MCI. We assessed the semantic and repetition priming effect in 13 individuals with MCI and 13 age-matched controls who engaged in a familiarity judgment task of famous names. In the semantic priming condition, the prime was the name of a member of the same occupation category as the target (Tom Cruise-Brad Pitt), while in the repetition priming condition the prime was the same name as the target (Charlie Chaplin-Charlie Chaplin). The results showed a defective priming effect in MCI in the semantic but not in the repetition priming condition. Specifically, when compared to controls, MCI patients did not show a facilitation effect in responding to the same occupation prime-target pairs, but they showed an equivalent facilitation effect when the target was the same name as the prime. The present results provide support to the hypothesis that the semantic impairments observed in MCI cannot be uniquely ascribed to a deficit in intentional access to semantic information. Instead, these findings point to the semantic nature of these deficits and, in particular, to a degraded representation of semantic information concerning famous people. Copyright © 2011 Elsevier Srl. All rights reserved.

A Semantic Graph Query Language

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaplan, I L

2006-10-16

Semantic graphs can be used to organize large amounts of information from a number of sources into one unified structure. A semantic query language provides a foundation for extracting information from the semantic graph. The graph query language described here provides a simple, powerful method for querying semantic graphs.

SSWAP: A Simple Semantic Web Architecture and Protocol for Semantic Web Services

USDA-ARS?s Scientific Manuscript database

SSWAP (Simple Semantic Web Architecture and Protocol) is an architecture, protocol, and platform for using reasoning to semantically integrate heterogeneous disparate data and services on the web. SSWAP is the driving technology behind the Virtual Plant Information Network, an NSF-funded semantic w...

A neuropsychologic profile of homosexual and heterosexual men and women.

PubMed

Wegesin, D J

1998-02-01

To examine the applicability of psychosexual differentiation theory to the development of sexual orientation, heterosexual (HT) women, HT men, lesbians, and gay men (20 per group) completed a lexical-decision/semantic monitoring task (LD/SM) to assess verbal ability, as well as a Water Level Task (WLT) and two Mental Rotation (MR) Tasks designed to assess spatial ability. All tests have been shown to differentiate HT men and women. Results replicated previously reported sex differences between the HT men and women. Further, gay men performed akin to HT women on the verbal task and the MR tasks, but not in the WLT. Lesbians, however, primarily performed in a sex-typical manner. The dissociation in sex-atypicality between lesbians and gay men is discussed in relation to neurobiological factors related to the development of both sex-dimorphic cognitive ability and sexual orientation.

A Qualitative Analysis of Power Differentials in Ethical Situations in Academia

PubMed Central

Gibson, Carter; Medeiros, Kelsey E.; Giorgini, Vincent; Mecca, Jensen T.; Devenport, Lynn D.; Connelly, Shane; Mumford, Michael D.

2014-01-01

Power and organizational hierarchies are ubiquitous to social institutions that form the foundation of modern society. Power differentials may act to constrain or enhance people's ability to make good ethical decisions. However, little scholarly work has examined perceptions of this important topic. The present effort seeks to address this issue by interviewing academics about hypothetical ethical problems that involve power differences among those involved. Academics discussed what they would do in these scenarios, often drawing on their own experiences. Using a think-aloud protocol, participants were prompted to discuss their reasoning and thinking behind their ethical decisions. These interview data were content analyzed using a semantic analysis program that identified a number of distinct ways that academics think about power differences and abuses in ethical situations. Implications of these findings are discussed. PMID:25356066

Semantic Priming for Coordinate Distant Concepts in Alzheimer's Disease Patients

ERIC Educational Resources Information Center

Perri, R.; Zannino, G. D.; Caltagirone, C.; Carlesimo, G. A.

2011-01-01

Semantic priming paradigms have been used to investigate semantic knowledge in patients with Alzheimer's disease (AD). While priming effects produced by prime-target pairs with associative relatedness reflect processes at both lexical and semantic levels, priming effects produced by words that are semantically related but not associated should…

Semantic Categories and Context in L2 Vocabulary Learning

ERIC Educational Resources Information Center

Bolger, Patrick; Zapata, Gabriela

2011-01-01

This article extends recent findings that presenting semantically related vocabulary simultaneously inhibits learning. It does so by adding story contexts. Participants learned 32 new labels for known concepts from four different semantic categories in stories that were either semantically related (one category per story) or semantically unrelated…

The Semantics of Plurals: A Defense of Singularism

ERIC Educational Resources Information Center

Florio, Salvatore

2010-01-01

In this dissertation, I defend "semantic singularism", which is the view that syntactically plural terms, such as "they" or "Russell and Whitehead", are semantically singular. A semantically singular term is a term that denotes a single entity. Semantic singularism is to be distinguished from "syntactic singularism", according to which…

Semantic Priming Effects in Normal versus Poor Readers

ERIC Educational Resources Information Center

Assink, Egbert M. H.; Van Bergen, Floor; Van Teeseling, Heleen; Knuijt, Paul P. N. A.

2004-01-01

The authors studied sensitivity to semantic priming, as distinct from semantic judgment, in poor readers. Association strength (high vs. low semantic association) was manipulated factorially with semantic association type (categoric vs. thematic association). Participants were 11-year-old poor readers (n = 15) who were matched with a group of…

Mapping the Structure of Semantic Memory

ERIC Educational Resources Information Center

Morais, Ana Sofia; Olsson, Henrik; Schooler, Lael J.

2013-01-01

Aggregating snippets from the semantic memories of many individuals may not yield a good map of an individual's semantic memory. The authors analyze the structure of semantic networks that they sampled from individuals through a new snowball sampling paradigm during approximately 6 weeks of 1-hr daily sessions. The semantic networks of individuals…

Representations for Semantic Learning Webs: Semantic Web Technology in Learning Support

ERIC Educational Resources Information Center

Dzbor, M.; Stutt, A.; Motta, E.; Collins, T.

2007-01-01

Recent work on applying semantic technologies to learning has concentrated on providing novel means of accessing and making use of learning objects. However, this is unnecessarily limiting: semantic technologies will make it possible to develop a range of educational Semantic Web services, such as interpretation, structure-visualization, support…

Individual Variability in the Semantic Processing of English Compound Words

ERIC Educational Resources Information Center

Schmidtke, Daniel; Van Dyke, Julie A.; Kuperman, Victor

2018-01-01

Semantic transparency effects during compound word recognition provide critical insight into the organization of semantic knowledge and the nature of semantic processing. The past 25 years of psycholinguistic research on compound semantic transparency has produced discrepant effects, leaving the existence and nature of its influence unresolved. In…

A Defense of Semantic Minimalism

ERIC Educational Resources Information Center

Kim, Su

2012-01-01

Semantic Minimalism is a position about the semantic content of declarative sentences, i.e., the content that is determined entirely by syntax. It is defined by the following two points: "Point 1": The semantic content is a complete/truth-conditional proposition. "Point 2": The semantic content is useful to a theory of…

Semantic distance effects on object and action naming.

PubMed

Vigliocco, Gabriella; Vinson, David P; Damian, Markus F; Levelt, Willem

2002-10-01

Graded interference effects were tested in a naming task, in parallel for objects and actions. Participants named either object or action pictures presented in the context of other pictures (blocks) that were either semantically very similar, or somewhat semantically similar or semantically dissimilar. We found that naming latencies for both object and action words were modulated by the semantic similarity between the exemplars in each block, providing evidence in both domains of graded semantic effects.

An Experiment in Scientific Code Semantic Analysis

NASA Technical Reports Server (NTRS)

Stewart, Mark E. M.

1998-01-01

This paper concerns a procedure that analyzes aspects of the meaning or semantics of scientific and engineering code. This procedure involves taking a user's existing code, adding semantic declarations for some primitive variables, and parsing this annotated code using multiple, distributed expert parsers. These semantic parser are designed to recognize formulae in different disciplines including physical and mathematical formulae and geometrical position in a numerical scheme. The parsers will automatically recognize and document some static, semantic concepts and locate some program semantic errors. Results are shown for a subroutine test case and a collection of combustion code routines. This ability to locate some semantic errors and document semantic concepts in scientific and engineering code should reduce the time, risk, and effort of developing and using these codes.

The benefits of sensorimotor knowledge: body-object interaction facilitates semantic processing.

PubMed

Siakaluk, Paul D; Pexman, Penny M; Sears, Christopher R; Wilson, Kim; Locheed, Keri; Owen, William J

2008-04-05

This article examined the effects of body-object interaction (BOI) on semantic processing. BOI measures perceptions of the ease with which a human body can physically interact with a word's referent. In Experiment 1, BOI effects were examined in 2 semantic categorization tasks (SCT) in which participants decided if words are easily imageable. Responses were faster and more accurate for high BOI words (e.g., mask) than for low BOI words (e.g., ship). In Experiment 2, BOI effects were examined in a semantic lexical decision task (SLDT), which taps both semantic feedback and semantic processing. The BOI effect was larger in the SLDT than in the SCT, suggesting that BOI facilitates both semantic feedback and semantic processing. The findings are consistent with the embodied cognition perspective (e.g., Barsalou's, 1999, Perceptual Symbols Theory), which proposes that sensorimotor interactions with the environment are incorporated in semantic knowledge. 2008 Cognitive Science Society, Inc.

Effects of semantic relatedness on recall of stimuli preceding emotional oddballs.

PubMed

Smith, Ryan M; Beversdorf, David Q

2008-07-01

Semantic and episodic memory networks function as highly interconnected systems, both relying on the hippocampal/medial temporal lobe complex (HC/MTL). Episodic memory encoding triggers the retrieval of semantic information, serving to incorporate contextual relationships between the newly acquired memory and existing semantic representations. While emotional material augments episodic memory encoding at the time of stimulus presentation, interactions between emotion and semantic memory that contribute to subsequent episodic recall are not well understood. Using a modified oddball task, we examined the modulatory effects of negative emotion on semantic interactions with episodic memory by measuring the free-recall of serially presented neutral or negative words varying in semantic relatedness. We found increased free-recall for words related to and preceding emotionally negative oddballs, suggesting that negative emotion can indirectly facilitate episodic free-recall by enhancing semantic contributions during encoding. Our findings demonstrate the ability of emotion and semantic memory to interact to mutually enhance free-recall.

Natural speech reveals the semantic maps that tile human cerebral cortex

PubMed Central

Huth, Alexander G.; de Heer, Wendy A.; Griffiths, Thomas L.; Theunissen, Frédéric E.; Gallant, Jack L.

2016-01-01

The meaning of language is represented in regions of the cerebral cortex collectively known as the “semantic system”. However, little of the semantic system has been mapped comprehensively, and the semantic selectivity of most regions is unknown. Here we systematically map semantic selectivity across the cortex using voxel-wise modeling of fMRI data collected while subjects listened to hours of narrative stories. We show that the semantic system is organized into intricate patterns that appear consistent across individuals. We then use a novel generative model to create a detailed semantic atlas. Our results suggest that most areas within the semantic system represent information about specific semantic domains, or groups of related concepts, and our atlas shows which domains are represented in each area. This study demonstrates that data-driven methods—commonplace in studies of human neuroanatomy and functional connectivity—provide a powerful and efficient means for mapping functional representations in the brain. PMID:27121839

Linked data scientometrics in semantic e-Science

NASA Astrophysics Data System (ADS)

Narock, Tom; Wimmer, Hayden

2017-03-01

The Semantic Web is inherently multi-disciplinary and many domains have taken advantage of semantic technologies. Yet, the geosciences are one of the fields leading the way in Semantic Web adoption and validation. Astronomy, Earth science, hydrology, and solar-terrestrial physics have seen a noteworthy amount of semantic integration. The geoscience community has been willing early adopters of semantic technologies and have provided essential feedback to the broader semantic web community. Yet, there has been no systematic study of the community as a whole and there exists no quantitative data on the impact and status of semantic technologies in the geosciences. We explore the applicability of Linked Data to scientometrics in the geosciences. In doing so, we gain an initial understanding of the breadth and depth of the Semantic Web in the geosciences. We identify what appears to be a transitionary period in the applicability of these technologies.

From Data to Semantic Information

NASA Astrophysics Data System (ADS)

Floridi, Luciano

2003-06-01

There is no consensus yet on the definition of semantic information. This paper contributes to the current debate by criticising and revising the Standard Definition of semantic Information (SDI) as meaningful data, in favour of the Dretske-Grice approach: meaningful and well-formed data constitute semantic information only if they also qualify as contingently truthful. After a brief introduction, SDI is criticised for providing necessary but insufficient conditions for the definition of semantic information. SDI is incorrect because truth-values do not supervene on semantic information, and misinformation (that is, false semantic information) is not a type of semantic information, but pseudo-information, that is not semantic information at all. This is shown by arguing that none of the reasons for interpreting misinformation as a type of semantic information is convincing, whilst there are compelling reasons to treat it as pseudo-information. As a consequence, SDI is revised to include a necessary truth-condition. The last section summarises the main results of the paper and indicates the important implications of the revised definition for the analysis of the deflationary theories of truth, the standard definition of knowledge and the classic, quantitative theory of semantic information.

Visual and semantic processing of living things and artifacts: an FMRI study.

PubMed

Zannino, Gian Daniele; Buccione, Ivana; Perri, Roberta; Macaluso, Emiliano; Lo Gerfo, Emanuele; Caltagirone, Carlo; Carlesimo, Giovanni A

2010-03-01

We carried out an fMRI study with a twofold purpose: to investigate the relationship between networks dedicated to semantic and visual processing and to address the issue of whether semantic memory is subserved by a unique network or by different subsystems, according to semantic category or feature type. To achieve our goals, we administered a word-picture matching task, with within-category foils, to 15 healthy subjects during scanning. Semantic distance between the target and the foil and semantic domain of the target-foil pairs were varied orthogonally. Our results suggest that an amodal, undifferentiated network for the semantic processing of living things and artifacts is located in the anterolateral aspects of the temporal lobes; in fact, activity in this substrate was driven by semantic distance, not by semantic category. By contrast, activity in ventral occipito-temporal cortex was driven by category, not by semantic distance. We interpret the latter finding as the effect exerted by systematic differences between living things and artifacts at the level of their structural representations and possibly of their lower-level visual features. Finally, we attempt to reconcile contrasting data in the neuropsychological and functional imaging literature on semantic substrate and category specificity.

Preservation of Person-Specific Semantic Knowledge in Semantic Dementia: Does Direct Personal Experience Have a Specific Role?

PubMed Central

Péron, Julie A.; Piolino, Pascale; Moal-Boursiquot, Sandrine Le; Biseul, Isabelle; Leray, Emmanuelle; Bon, Laetitia; Desgranges, Béatrice; Eustache, Francis; Belliard, Serge

2015-01-01

Semantic dementia patients seem to have better knowledge of information linked to the self. More specifically, despite having severe semantic impairment, these patients show that they have more general information about the people they know personally by direct experience than they do about other individuals they know indirectly. However, the role of direct personal experience remains debated because of confounding factors such as frequency, recency of exposure, and affective relevance. We performed an exploratory study comparing the performance of five semantic dementia patients with that of 10 matched healthy controls on the recognition (familiarity judgment) and identification (biographic information recall) of personally familiar names vs. famous names. As expected, intergroup comparisons indicated a semantic breakdown in semantic dementia patients as compared with healthy controls. Moreover, unlike healthy controls, the semantic dementia patients recognized and identified personally familiar names better than they did famous names. This pattern of results suggests that direct personal experience indeed plays a specific role in the relative preservation of person-specific semantic meaning in semantic dementia. We discuss the role of direct personal experience on the preservation of semantic knowledge and the potential neurophysiological mechanisms underlying these processes. PMID:26635578

Verbal and non-verbal semantic impairment: From fluent primary progressive aphasia to semantic dementia

PubMed Central

Senaha, Mirna Lie Hosogi; Caramelli, Paulo; Porto, Claudia Sellitto; Nitrini, Ricardo

2007-01-01

Selective disturbances of semantic memory have attracted the interest of many investigators and the question of the existence of single or multiple semantic systems remains a very controversial theme in the literature. Objectives To discuss the question of multiple semantic systems based on a longitudinal study of a patient who presented semantic dementia from fluent primary progressive aphasia. Methods A 66 year-old woman with selective impairment of semantic memory was examined on two occasions, undergoing neuropsychological and language evaluations, the results of which were compared to those of three paired control individuals. Results In the first evaluation, physical examination was normal and the score on the Mini-Mental State Examination was 26. Language evaluation revealed fluent speech, anomia, disturbance in word comprehension, preservation of the syntactic and phonological aspects of the language, besides surface dyslexia and dysgraphia. Autobiographical and episodic memories were relatively preserved. In semantic memory tests, the following dissociation was found: disturbance of verbal semantic memory with preservation of non-verbal semantic memory. Magnetic resonance of the brain revealed marked atrophy of the left anterior temporal lobe. After 14 months, the difficulties in verbal semantic memory had become more severe and the semantic disturbance, limited initially to the linguistic sphere, had worsened to involve non-verbal domains. Conclusions Given the dissociation found in the first examination, we believe there is sufficient clinical evidence to refute the existence of a unitary semantic system. PMID:29213389

Relations between Short-term Memory Deficits, Semantic Processing, and Executive Function

PubMed Central

Allen, Corinne M.; Martin, Randi C.; Martin, Nadine

2012-01-01

Background Previous research has suggested separable short-term memory (STM) buffers for the maintenance of phonological and lexical-semantic information, as some patients with aphasia show better ability to retain semantic than phonological information and others show the reverse. Recently, researchers have proposed that deficits to the maintenance of semantic information in STM are related to executive control abilities. Aims The present study investigated the relationship of executive function abilities with semantic and phonological short-term memory (STM) and semantic processing in such patients, as some previous research has suggested that semantic STM deficits and semantic processing abilities are critically related to specific or general executive function deficits. Method and Procedures 20 patients with aphasia and STM deficits were tested on measures of short-term retention, semantic processing, and both complex and simple executive function tasks. Outcome and Results In correlational analyses, we found no relation between semantic STM and performance on simple or complex executive function tasks. In contrast, phonological STM was related to executive function performance in tasks that had a verbal component, suggesting that performance in some executive function tasks depends on maintaining or rehearsing phonological codes. Although semantic STM was not related to executive function ability, performance on semantic processing tasks was related to executive function, perhaps due to similar executive task requirements in both semantic processing and executive function tasks. Conclusions Implications for treatment and interpretations of executive deficits are discussed. PMID:22736889

Principal semantic components of language and the measurement of meaning.

PubMed

Samsonovich, Alexei V; Samsonovic, Alexei V; Ascoli, Giorgio A

2010-06-11

Metric systems for semantics, or semantic cognitive maps, are allocations of words or other representations in a metric space based on their meaning. Existing methods for semantic mapping, such as Latent Semantic Analysis and Latent Dirichlet Allocation, are based on paradigms involving dissimilarity metrics. They typically do not take into account relations of antonymy and yield a large number of domain-specific semantic dimensions. Here, using a novel self-organization approach, we construct a low-dimensional, context-independent semantic map of natural language that represents simultaneously synonymy and antonymy. Emergent semantics of the map principal components are clearly identifiable: the first three correspond to the meanings of "good/bad" (valence), "calm/excited" (arousal), and "open/closed" (freedom), respectively. The semantic map is sufficiently robust to allow the automated extraction of synonyms and antonyms not originally in the dictionaries used to construct the map and to predict connotation from their coordinates. The map geometric characteristics include a limited number ( approximately 4) of statistically significant dimensions, a bimodal distribution of the first component, increasing kurtosis of subsequent (unimodal) components, and a U-shaped maximum-spread planar projection. Both the semantic content and the main geometric features of the map are consistent between dictionaries (Microsoft Word and Princeton's WordNet), among Western languages (English, French, German, and Spanish), and with previously established psychometric measures. By defining the semantics of its dimensions, the constructed map provides a foundational metric system for the quantitative analysis of word meaning. Language can be viewed as a cumulative product of human experiences. Therefore, the extracted principal semantic dimensions may be useful to characterize the general semantic dimensions of the content of mental states. This is a fundamental step toward a universal metric system for semantics of human experiences, which is necessary for developing a rigorous science of the mind.

Creativity and positive symptoms in schizophrenia revisited: Structural connectivity analysis with diffusion tensor imaging.

PubMed

Son, Shuraku; Kubota, Manabu; Miyata, Jun; Fukuyama, Hidenao; Aso, Toshihiko; Urayama, Shin-ichi; Murai, Toshiya; Takahashi, Hidehiko

2015-05-01

Both creativity and schizotypy are suggested to be manifestations of the hyperactivation of unusual or remote concepts/words. However, the results of studies on creativity in schizophrenia are diverse, possibly due to the multifaceted aspects of creativity and difficulties of differentiating adaptive creativity from pathological schizotypy/positive symptoms. To date, there have been no detailed studies comprehensively investigating creativity, positive symptoms including delusions, and their neural bases in schizophrenia. In this study, we investigated 43 schizophrenia and 36 healthy participants using diffusion tensor imaging. We used idea, design, and verbal (semantic and phonological) fluency tests as creativity scores and Peters Delusions Inventory as delusion scores. Subsequently, we investigated group differences in every psychological score, correlations between fluency and delusions, and relationships between these scores and white matter integrity using tract-based spatial statistics (TBSS). In schizophrenia, idea and verbal fluency were significantly lower in general, and delusion score was higher than in healthy controls, whereas there were no group differences in design fluency. We also found positive correlation between phonological fluency and delusions in schizophrenia. By correlation analyses using TBSS, we found that the anterior part of corpus callosum was the substantially overlapped area, negatively correlated with both phonological fluency and delusion severity. Our results suggest that the anterior interhemispheric dysconnectivity might be associated with executive dysfunction, and disinhibited automatic spreading activation in the semantic network was manifested as uncontrollable phonological fluency or delusions. This dysconnectivity could be one possible neural basis that differentiates pathological positive symptoms from adaptive creativity. Copyright © 2015 Elsevier B.V. All rights reserved.

Virtual patients to explore and develop clinical case summary statement skills amongst Japanese resident physicians: a mixed methods study.

PubMed

Heist, Brian S; Kishida, Naoki; Deshpande, Gautam; Hamaguchi, Sugihiro; Kobayashi, Hiroyuki

2016-02-01

In Western clinical training, formulation of a summary statement (SS) is a core exercise for articulation, evaluation, and improvement of clinical reasoning (CR). In Japanese clinical training, structured guidance in developing CR, including opportunity for SS practice, is uncommon, and the present status of case summarization skills is unclear. We used Virtual Patients (VPs) to explore Japanese junior residents' SS styles and the effectiveness of VPs on improving SS quality. All first-year junior resident physicians at 4 residency programs (n = 54) were assigned randomized sequences of 5 VP modules, rolled out at 6 day intervals. During each module, participants free-texted a case summary and then reviewed a model summary. Thematic analysis was used to identify SS styles and each SS was categorized accordingly. Frequency of SS styles, and SS CR quality determined by 1) an internally developed Key Feature rubric and 2) demonstration of semantic qualification, were compared across modules. Four SS styles were identified: numbered features matched to differential diagnoses, differential diagnoses with supportive comments, feature listing, and narrative summarization. From module #1 to #5, significant increases in the narrative summarization SS style (p = 0.016), SS CR quality score (p = 0.021) and percentage of semantically driven SS (p = 0.003) were observed. Our study of Japanese junior residents identified distinct clinical case summary statement styles, and observed adoption of the narrative summarization style and improvement in the CR quality of summary statements during a series of VP cases.

Linguistic and Non-Linguistic Semantic Processing in Individuals with Autism Spectrum Disorders: An ERP Study

ERIC Educational Resources Information Center

Coderre, Emily L.; Chernenok, Mariya; Gordon, Barry; Ledoux, Kerry

2017-01-01

Individuals with autism spectrum disorders (ASD) experience difficulties with language, particularly higher-level functions like semantic integration. Yet some studies indicate that semantic processing of non-linguistic stimuli is not impaired, suggesting a language-specific deficit in semantic processing. Using a semantic priming task, we…

"Pre-Semantic" Cognition Revisited: Critical Differences between Semantic Aphasia and Semantic Dementia

ERIC Educational Resources Information Center

Jefferies, Elizabeth; Rogers, Timothy T.; Hopper, Samantha; Lambon Ralph, Matthew A.

2010-01-01

Patients with semantic dementia show a specific pattern of impairment on both verbal and non-verbal "pre-semantic" tasks, e.g., reading aloud, past tense generation, spelling to dictation, lexical decision, object decision, colour decision and delayed picture copying. All seven tasks are characterised by poorer performance for items that are…

Shared Features Dominate Semantic Richness Effects for Concrete Concepts

ERIC Educational Resources Information Center

Grondin, Ray; Lupker, Stephen J.; McRae, Ken

2009-01-01

When asked to list semantic features for concrete concepts, participants list many features for some concepts and few for others. Concepts with many semantic features are processed faster in lexical and semantic decision tasks [Pexman, P. M., Lupker, S. J., & Hino, Y. (2002). "The impact of feedback semantics in visual word recognition:…

Modulation of Task Demands Suggests That Semantic Processing Interferes with the Formation of Episodic Associations

ERIC Educational Resources Information Center

Long, Nicole M.; Kahana, Michael J.

2017-01-01

Although episodic and semantic memory share overlapping neural mechanisms, it remains unclear how our pre-existing semantic associations modulate the formation of new, episodic associations. When freely recalling recently studied words, people rely on both episodic and semantic associations, shown through temporal and semantic clustering of…

Verb Production during Action Naming in Semantic Dementia

ERIC Educational Resources Information Center

Meligne, D.; Fossard, M.; Belliard, S.; Moreaud, O.; Duvignau, K.; Demonet, J.-F.

2011-01-01

In contrast with widely documented deficits of semantic knowledge relating to object concepts and the corresponding nouns in semantic dementia (SD), little is known about action semantics and verb production in SD. The degradation of action semantic knowledge was studied in 5 patients with SD compared with 17 matched control participants in an…

The Function of Semantics in Automated Language Processing.

ERIC Educational Resources Information Center

Pacak, Milos; Pratt, Arnold W.

This paper is a survey of some of the major semantic models that have been developed for automated semantic analysis of natural language. Current approaches to semantic analysis and logical interference are based mainly on models of human cognitive processes such as Quillian's semantic memory, Simmon's Protosynthex III and others. All existing…

Attractor Dynamics and Semantic Neighborhood Density: Processing Is Slowed by Near Neighbors and Speeded by Distant Neighbors

ERIC Educational Resources Information Center

Mirman, Daniel; Magnuson, James S.

2008-01-01

The authors investigated semantic neighborhood density effects on visual word processing to examine the dynamics of activation and competition among semantic representations. Experiment 1 validated feature-based semantic representations as a basis for computing semantic neighborhood density and suggested that near and distant neighbors have…

The Masked Semantic Priming Effect Is Task Dependent: Reconsidering the Automatic Spreading Activation Process

ERIC Educational Resources Information Center

de Wit, Bianca; Kinoshita, Sachiko

2015-01-01

Semantic priming effects are popularly explained in terms of an automatic spreading activation process, according to which the activation of a node in a semantic network spreads automatically to interconnected nodes, preactivating a semantically related word. It is expected from this account that semantic priming effects should be routinely…

Interpreting semantic clustering effects in free recall.

PubMed

Manning, Jeremy R; Kahana, Michael J

2012-07-01

The order in which participants choose to recall words from a studied list of randomly selected words provides insights into how memories of the words are represented, organised, and retrieved. One pervasive finding is that when a pair of semantically related words (e.g., "cat" and "dog") is embedded in the studied list, the related words are often recalled successively. This tendency to successively recall semantically related words is termed semantic clustering (Bousfield, 1953; Bousfield & Sedgewick, 1944; Cofer, Bruce, & Reicher, 1966). Measuring semantic clustering effects requires making assumptions about which words participants consider to be similar in meaning. However, it is often difficult to gain insights into individual participants' internal semantic models, and for this reason researchers typically rely on standardised semantic similarity metrics. Here we use simulations to gain insights into the expected magnitudes of semantic clustering effects given systematic differences between participants' internal similarity models and the similarity metric used to quantify the degree of semantic clustering. Our results provide a number of useful insights into the interpretation of semantic clustering effects in free recall.

Past, present, and prospects: Reflections 40 years on from the selective impairment of semantic memory (Warrington, 1975).

PubMed

McCarthy, Rosaleen A; Warrington, Elizabeth K

2016-10-01

We summarize the main findings and conclusions of Warrington's (1975) paper, The Selective Impairment of Semantic memory, a neuropsychological paper that described three cases with degenerative neurological conditions [Warrington, E. K. (1975). The selective impairment of semantic memory. The Quarterly Journal of Experimental Psychology, 27, 635-657]. We consider the developments that have followed from its publication and give a selective overview of the field in 2014. The initial impact of the paper was on neuropsychological investigations of semantic loss followed some 14 years later by the identification of Semantic Dementia (the condition shown by the original cases) as a distinctive form of degenerative disease with unique clinical and pathological characteristics. We discuss the distinction between disorders of semantic storage and refractory semantic access, the evidence for category- and modality-specific impairments of semantics, and the light that has been shed on the structure and organization of semantic memory. Finally we consider the relationship between semantic memory and the skills of reading and writing, phonological processing, and autobiographical memory.

Multi-talker background and semantic priming effect

PubMed Central

Dekerle, Marie; Boulenger, Véronique; Hoen, Michel; Meunier, Fanny

2014-01-01

The reported studies have aimed to investigate whether informational masking in a multi-talker background relies on semantic interference between the background and target using an adapted semantic priming paradigm. In 3 experiments, participants were required to perform a lexical decision task on a target item embedded in backgrounds composed of 1–4 voices. These voices were Semantically Consistent (SC) voices (i.e., pronouncing words sharing semantic features with the target) or Semantically Inconsistent (SI) voices (i.e., pronouncing words semantically unrelated to each other and to the target). In the first experiment, backgrounds consisted of 1 or 2 SC voices. One and 2 SI voices were added in Experiments 2 and 3, respectively. The results showed a semantic priming effect only in the conditions where the number of SC voices was greater than the number of SI voices, suggesting that semantic priming depended on prime intelligibility and strategic processes. However, even if backgrounds were composed of 3 or 4 voices, reducing intelligibility, participants were able to recognize words from these backgrounds, although no semantic priming effect on the targets was observed. Overall this finding suggests that informational masking can occur at a semantic level if intelligibility is sufficient. Based on the Effortfulness Hypothesis, we also suggest that when there is an increased difficulty in extracting target signals (caused by a relatively high number of voices in the background), more cognitive resources were allocated to formal processes (i.e., acoustic and phonological), leading to a decrease in available resources for deeper semantic processing of background words, therefore preventing semantic priming from occurring. PMID:25400572

The role of the right hemisphere in semantic control: A case-series comparison of right and left hemisphere stroke

PubMed Central

Thompson, Hannah E.; Henshall, Lauren; Jefferies, Elizabeth

2016-01-01

Semantic control processes guide conceptual retrieval so that we are able to focus on non-dominant associations and features when these are required for the task or context, yet the neural basis of semantic control is not fully understood. Neuroimaging studies have emphasised the role of left inferior frontal gyrus (IFG) in controlled retrieval, while neuropsychological investigations of semantic control deficits have almost exclusively focussed on patients with left-sided damage (e.g., patients with semantic aphasia, SA). Nevertheless, activation in fMRI during demanding semantic tasks typically extends to right IFG. To investigate the role of the right hemisphere (RH) in semantic control, we compared nine RH stroke patients with 21 left-hemisphere SA patients, 11 mild SA cases and 12 healthy, aged-matched controls on semantic and executive tasks, plus experimental tasks that manipulated semantic control in paradigms particularly sensitive to RH damage. RH patients had executive deficits to parallel SA patients but they performed well on standard semantic tests. Nevertheless, multimodal semantic control deficits were found in experimental tasks involving facial emotions and the ‘summation’ of meaning across multiple items. On these tasks, RH patients showed effects similar to those in SA cases – multimodal deficits that were sensitive to distractor strength and cues and miscues, plus increasingly poor performance in cyclical matching tasks which repeatedly probed the same set of concepts. Thus, despite striking differences in single-item comprehension, evidence presented here suggests semantic control is bilateral, and disruption of this component of semantic cognition can be seen following damage to either hemisphere. PMID:26945505

The association of personal semantic memory to identity representations: insight into higher-order networks of autobiographical contents.

PubMed

Grilli, Matthew D

2017-11-01

Identity representations are higher-order knowledge structures that organise autobiographical memories on the basis of personality and role-based themes of one's self-concept. In two experiments, the extent to which different types of personal semantic content are reflected in these higher-order networks of memories was investigated. Healthy, young adult participants generated identity representations that varied in remoteness of formation and verbally reflected on these themes in an open-ended narrative task. The narrative responses were scored for retrieval of episodic, experience-near personal semantic and experience-far (i.e., abstract) personal semantic contents. Results revealed that to reflect on remotely formed identity representations, experience-far personal semantic contents were retrieved more than experience-near personal semantic contents. In contrast, to reflect on recently formed identity representations, experience-near personal semantic contents were retrieved more than experience-far personal semantic contents. Although episodic memory contents were retrieved less than both personal semantic content types to reflect on remotely formed identity representations, this content type was retrieved at a similar frequency as experience-far personal semantic content to reflect on recently formed identity representations. These findings indicate that the association of personal semantic content to identity representations is robust and related to time since acquisition of these knowledge structures.

The structure of semantic person memory: evidence from semantic priming in person recognition.

PubMed

Wiese, Holger

2011-11-01

This paper reviews research on the structure of semantic person memory as examined with semantic priming. In this experimental paradigm, a familiarity decision on a target face or written name is usually faster when it is preceded by a related as compared to an unrelated prime. This effect has been shown to be relatively short lived and susceptible to interfering items. Moreover, semantic priming can cross stimulus domains, such that a written name can prime a target face and vice versa. However, it remains controversial whether representations of people are stored in associative networks based on co-occurrence, or in more abstract semantic categories. In line with prominent cognitive models of face recognition, which explain semantic priming by shared semantic information between prime and target, recent research demonstrated that priming could be obtained from purely categorically related, non-associated prime/target pairs. Although strategic processes, such as expectancy and retrospective matching likely contribute, there is also evidence for a non-strategic contribution to priming, presumably related to spreading activation. Finally, a semantic priming effect has been demonstrated in the N400 event-related potential (ERP) component, which may reflect facilitated access to semantic information. It is concluded that categorical relatedness is one organizing principle of semantic person memory. ©2011 The British Psychological Society.

Measuring effectiveness of semantic cues in degraded English sentences in non-native listeners.

PubMed

Shi, Lu-Feng

2014-01-01

This study employed Boothroyd and Nittrouer's k (1988) to directly quantify effectiveness in native versus non-native listeners' use of semantic cues. Listeners were presented speech-perception-in-noise sentences processed at three levels of concurrent multi-talker babble and reverberation. For each condition, 50 sentences with multiple semantic cues and 50 with minimum semantic cues were randomly presented. Listeners verbally reported and wrote down the target words. The metric, k, was derived from percent-correct scores for sentences with and without semantics. Ten native and 33 non-native listeners participated. The presence of semantics increased recognition benefit by over 250% for natives, but access to semantics remained limited for non-native listeners (90-135%). The k was comparable across conditions for native listeners, but level-dependent for non-natives. The k for non-natives was significantly different from 1 in all conditions, suggesting semantic cues, though reduced in importance in difficult conditions, were helpful for non-natives. Non-natives as a group were not as effective in using semantics to facilitate English sentence recognition as natives. Poor listening conditions were particularly adverse to the use of semantics in non-natives, who may rely on clear acoustic-phonetic cues before benefitting from semantic cues when recognizing connected speech.

Semantic error patterns on the Boston Naming Test in normal aging, amnestic mild cognitive impairment, and mild Alzheimer's disease: is there semantic disruption?

PubMed

Balthazar, Marcio Luiz Figueredo; Cendes, Fernando; Damasceno, Benito Pereira

2008-11-01

Naming difficulty is common in Alzheimer's disease (AD), but the nature of this problem is not well established. The authors investigated the presence of semantic breakdown and the pattern of general and semantic errors in patients with mild AD, patients with amnestic mild cognitive impairment (aMCI), and normal controls by examining their spontaneous answers on the Boston Naming Test (BNT) and verifying whether they needed or were benefited by semantic and phonemic cues. The errors in spontaneous answers were classified in four mutually exclusive categories (semantic errors, visual paragnosia, phonological errors, and omission errors), and the semantic errors were further subclassified as coordinate, superordinate, and circumlocutory. Patients with aMCI performed normally on the BNT and needed fewer semantic and phonemic cues than patients with mild AD. After semantic cues, subjects with aMCI and control subjects gave more correct answers than patients with mild AD, but after phonemic cues, there was no difference between the three groups, suggesting that the low performance of patients with AD cannot be completely explained by semantic breakdown. Patterns of spontaneous naming errors and subtypes of semantic errors were similar in the three groups, with decreasing error frequency from coordinate to superordinate to circumlocutory subtypes.

No one way ticket from orthography to semantics in recognition memory: N400 and P200 effects of associations.

PubMed

Stuellein, Nicole; Radach, Ralph R; Jacobs, Arthur M; Hofmann, Markus J

2016-05-15

Computational models of word recognition already successfully used associative spreading from orthographic to semantic levels to account for false memories. But can they also account for semantic effects on event-related potentials in a recognition memory task? To address this question, target words in the present study had either many or few semantic associates in the stimulus set. We found larger P200 amplitudes and smaller N400 amplitudes for old words in comparison to new words. Words with many semantic associates led to larger P200 amplitudes and a smaller N400 in comparison to words with a smaller number of semantic associations. We also obtained inverted response time and accuracy effects for old and new words: faster response times and fewer errors were found for old words that had many semantic associates, whereas new words with a large number of semantic associates produced slower response times and more errors. Both behavioral and electrophysiological results indicate that semantic associations between words can facilitate top-down driven lexical access and semantic integration in recognition memory. Our results support neurophysiologically plausible predictions of the Associative Read-Out Model, which suggests top-down connections from semantic to orthographic layers. Copyright © 2016 Elsevier B.V. All rights reserved.

Intrusive effects of semantic information on visual selective attention.

PubMed

Malcolm, George L; Rattinger, Michelle; Shomstein, Sarah

2016-10-01

Every object is represented by semantic information in extension to its low-level properties. It is well documented that such information biases attention when it is necessary for an ongoing task. However, whether semantic relationships influence attentional selection when they are irrelevant to the ongoing task remains an open question. The ubiquitous nature of semantic information suggests that it could bias attention even when these properties are irrelevant. In the present study, three objects appeared on screen, two of which were semantically related. After a varying time interval, a target or distractor appeared on top of each object. The objects' semantic relationships never predicted the target location. Despite this, a semantic bias on attentional allocation was observed, with an initial, transient bias to semantically related objects. Further experiments demonstrated that this effect was contingent on the objects being attended: if an object never contained the target, it no longer exerted a semantic influence. In a final set of experiments, we demonstrated that the semantic bias is robust and appears even in the presence of more predictive cues (spatial probability). These results suggest that as long as an object is attended, its semantic properties bias attention, even if it is irrelevant to an ongoing task and if more predictive factors are available.

Semantic attributes are encoded in human electrocorticographic signals during visual object recognition.

PubMed

Rupp, Kyle; Roos, Matthew; Milsap, Griffin; Caceres, Carlos; Ratto, Christopher; Chevillet, Mark; Crone, Nathan E; Wolmetz, Michael

2017-03-01

Non-invasive neuroimaging studies have shown that semantic category and attribute information are encoded in neural population activity. Electrocorticography (ECoG) offers several advantages over non-invasive approaches, but the degree to which semantic attribute information is encoded in ECoG responses is not known. We recorded ECoG while patients named objects from 12 semantic categories and then trained high-dimensional encoding models to map semantic attributes to spectral-temporal features of the task-related neural responses. Using these semantic attribute encoding models, untrained objects were decoded with accuracies comparable to whole-brain functional Magnetic Resonance Imaging (fMRI), and we observed that high-gamma activity (70-110Hz) at basal occipitotemporal electrodes was associated with specific semantic dimensions (manmade-animate, canonically large-small, and places-tools). Individual patient results were in close agreement with reports from other imaging modalities on the time course and functional organization of semantic processing along the ventral visual pathway during object recognition. The semantic attribute encoding model approach is critical for decoding objects absent from a training set, as well as for studying complex semantic encodings without artificially restricting stimuli to a small number of semantic categories. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Considering the role of semantic memory in episodic future thinking: evidence from semantic dementia.

PubMed

Irish, Muireann; Addis, Donna Rose; Hodges, John R; Piguet, Olivier

2012-07-01

Semantic dementia is a progressive neurodegenerative condition characterized by the profound and amodal loss of semantic memory in the context of relatively preserved episodic memory. In contrast, patients with Alzheimer's disease typically display impairments in episodic memory, but with semantic deficits of a much lesser magnitude than in semantic dementia. Our understanding of episodic memory retrieval in these cohorts has greatly increased over the last decade, however, we know relatively little regarding the ability of these patients to imagine and describe possible future events, and whether episodic future thinking is mediated by divergent neural substrates contingent on dementia subtype. Here, we explored episodic future thinking in patients with semantic dementia (n=11) and Alzheimer's disease (n=11), in comparison with healthy control participants (n=10). Participants completed a battery of tests designed to probe episodic and semantic thinking across past and future conditions, as well as standardized tests of episodic and semantic memory. Further, all participants underwent magnetic resonance imaging. Despite their relatively intact episodic retrieval for recent past events, the semantic dementia cohort showed significant impairments for episodic future thinking. In contrast, the group with Alzheimer's disease showed parallel deficits across past and future episodic conditions. Voxel-based morphometry analyses confirmed that atrophy in the left inferior temporal gyrus and bilateral temporal poles, regions strongly implicated in semantic memory, correlated significantly with deficits in episodic future thinking in semantic dementia. Conversely, episodic future thinking performance in Alzheimer's disease correlated with atrophy in regions associated with episodic memory, namely the posterior cingulate, parahippocampal gyrus and frontal pole. These distinct neuroanatomical substrates contingent on dementia group were further qualified by correlational analyses that confirmed the relation between semantic memory deficits and episodic future thinking in semantic dementia, in contrast with the role of episodic memory deficits and episodic future thinking in Alzheimer's disease. Our findings demonstrate that semantic knowledge is critical for the construction of novel future events, providing the necessary scaffolding into which episodic details can be integrated. Further research is necessary to elucidate the precise contribution of semantic memory to future thinking, and to explore how deficits in self-projection manifest on behavioural and social levels in different dementia subtypes.

SSWAP: A Simple Semantic Web Architecture and Protocol for semantic web services

PubMed Central

Gessler, Damian DG; Schiltz, Gary S; May, Greg D; Avraham, Shulamit; Town, Christopher D; Grant, David; Nelson, Rex T

2009-01-01

Background SSWAP (Simple Semantic Web Architecture and Protocol; pronounced "swap") is an architecture, protocol, and platform for using reasoning to semantically integrate heterogeneous disparate data and services on the web. SSWAP was developed as a hybrid semantic web services technology to overcome limitations found in both pure web service technologies and pure semantic web technologies. Results There are currently over 2400 resources published in SSWAP. Approximately two dozen are custom-written services for QTL (Quantitative Trait Loci) and mapping data for legumes and grasses (grains). The remaining are wrappers to Nucleic Acids Research Database and Web Server entries. As an architecture, SSWAP establishes how clients (users of data, services, and ontologies), providers (suppliers of data, services, and ontologies), and discovery servers (semantic search engines) interact to allow for the description, querying, discovery, invocation, and response of semantic web services. As a protocol, SSWAP provides the vocabulary and semantics to allow clients, providers, and discovery servers to engage in semantic web services. The protocol is based on the W3C-sanctioned first-order description logic language OWL DL. As an open source platform, a discovery server running at (as in to "swap info") uses the description logic reasoner Pellet to integrate semantic resources. The platform hosts an interactive guide to the protocol at , developer tools at , and a portal to third-party ontologies at (a "swap meet"). Conclusion SSWAP addresses the three basic requirements of a semantic web services architecture (i.e., a common syntax, shared semantic, and semantic discovery) while addressing three technology limitations common in distributed service systems: i.e., i) the fatal mutability of traditional interfaces, ii) the rigidity and fragility of static subsumption hierarchies, and iii) the confounding of content, structure, and presentation. SSWAP is novel by establishing the concept of a canonical yet mutable OWL DL graph that allows data and service providers to describe their resources, to allow discovery servers to offer semantically rich search engines, to allow clients to discover and invoke those resources, and to allow providers to respond with semantically tagged data. SSWAP allows for a mix-and-match of terms from both new and legacy third-party ontologies in these graphs. PMID:19775460

Effectiveness of Semantic Therapy for Word-Finding Difficulties in Pupils with Persistent Language Impairments: A Randomized Control Trial

ERIC Educational Resources Information Center

Ebbels, Susan H.; Nicoll, Hilary; Clark, Becky; Eachus, Beth; Gallagher, Aoife L.; Horniman, Karen; Jennings, Mary; McEvoy, Kate; Nimmo, Liz; Turner, Gail

2012-01-01

Background: Word-finding difficulties (WFDs) in children have been hypothesized to be caused at least partly by poor semantic knowledge. Therefore, improving semantic knowledge should decrease word-finding errors. Previous studies of semantic therapy for WFDs are inconclusive. Aims: To investigate the effectiveness of semantic therapy for…

The Influence of Semantic Neighbours on Visual Word Recognition

ERIC Educational Resources Information Center

Yates, Mark

2012-01-01

Although it is assumed that semantics is a critical component of visual word recognition, there is still much that we do not understand. One recent way of studying semantic processing has been in terms of semantic neighbourhood (SN) density, and this research has shown that semantic neighbours facilitate lexical decisions. However, it is not clear…

Structure Discovery in Large Semantic Graphs Using Extant Ontological Scaling and Descriptive Statistics

DOE Office of Scientific and Technical Information (OSTI.GOV)

al-Saffar, Sinan; Joslyn, Cliff A.; Chappell, Alan R.

As semantic datasets grow to be very large and divergent, there is a need to identify and exploit their inherent semantic structure for discovery and optimization. Towards that end, we present here a novel methodology to identify the semantic structures inherent in an arbitrary semantic graph dataset. We first present the concept of an extant ontology as a statistical description of the semantic relations present amongst the typed entities modeled in the graph. This serves as a model of the underlying semantic structure to aid in discovery and visualization. We then describe a method of ontological scaling in which themore » ontology is employed as a hierarchical scaling filter to infer different resolution levels at which the graph structures are to be viewed or analyzed. We illustrate these methods on three large and publicly available semantic datasets containing more than one billion edges each. Keywords-Semantic Web; Visualization; Ontology; Multi-resolution Data Mining;« less

Co-occurrence frequency evaluated with large language corpora boosts semantic priming effects.

PubMed

Brunellière, Angèle; Perre, Laetitia; Tran, ThiMai; Bonnotte, Isabelle

2017-09-01

In recent decades, many computational techniques have been developed to analyse the contextual usage of words in large language corpora. The present study examined whether the co-occurrence frequency obtained from large language corpora might boost purely semantic priming effects. Two experiments were conducted: one with conscious semantic priming, the other with subliminal semantic priming. Both experiments contrasted three semantic priming contexts: an unrelated priming context and two related priming contexts with word pairs that are semantically related and that co-occur either frequently or infrequently. In the conscious priming presentation (166-ms stimulus-onset asynchrony, SOA), a semantic priming effect was recorded in both related priming contexts, which was greater with higher co-occurrence frequency. In the subliminal priming presentation (66-ms SOA), no significant priming effect was shown, regardless of the related priming context. These results show that co-occurrence frequency boosts pure semantic priming effects and are discussed with reference to models of semantic network.

Concept-oriented indexing of video databases: toward semantic sensitive retrieval and browsing.

PubMed

Fan, Jianping; Luo, Hangzai; Elmagarmid, Ahmed K

2004-07-01

Digital video now plays an important role in medical education, health care, telemedicine and other medical applications. Several content-based video retrieval (CBVR) systems have been proposed in the past, but they still suffer from the following challenging problems: semantic gap, semantic video concept modeling, semantic video classification, and concept-oriented video database indexing and access. In this paper, we propose a novel framework to make some advances toward the final goal to solve these problems. Specifically, the framework includes: 1) a semantic-sensitive video content representation framework by using principal video shots to enhance the quality of features; 2) semantic video concept interpretation by using flexible mixture model to bridge the semantic gap; 3) a novel semantic video-classifier training framework by integrating feature selection, parameter estimation, and model selection seamlessly in a single algorithm; and 4) a concept-oriented video database organization technique through a certain domain-dependent concept hierarchy to enable semantic-sensitive video retrieval and browsing.

Syntactic and semantic processing of Chinese middle sentences: evidence from event-related potentials.

PubMed

Zeng, Tao; Mao, Wen; Lu, Qing

2016-05-25

Scalp-recorded event-related potentials are known to be sensitive to particular aspects of sentence processing. The N400 component is widely recognized as an effect closely related to lexical-semantic processing. The absence of an N400 effect in participants performing tasks in Indo-European languages has been considered evidence that failed syntactic category processing appears to block lexical-semantic integration and that syntactic structure building is a prerequisite of semantic analysis. An event-related potential experiment was designed to investigate whether such syntactic primacy can be considered to apply equally to Chinese sentence processing. Besides correct middles, sentences with either single semantic or single syntactic violation as well as double syntactic and semantic anomaly were used in the present research. Results showed that both purely semantic and combined violation induced a broad negativity in the time window 300-500 ms, indicating the independence of lexical-semantic integration. These findings provided solid evidence that lexical-semantic parsing plays a crucial role in Chinese sentence comprehension.

Semantic richness effects in lexical decision: The role of feedback.

PubMed

Yap, Melvin J; Lim, Gail Y; Pexman, Penny M

2015-11-01

Across lexical processing tasks, it is well established that words with richer semantic representations are recognized faster. This suggests that the lexical system has access to meaning before a word is fully identified, and is consistent with a theoretical framework based on interactive and cascaded processing. Specifically, semantic richness effects are argued to be produced by feedback from semantic representations to lower-level representations. The present study explores the extent to which richness effects are mediated by feedback from lexical- to letter-level representations. In two lexical decision experiments, we examined the joint effects of stimulus quality and four semantic richness dimensions (imageability, number of features, semantic neighborhood density, semantic diversity). With the exception of semantic diversity, robust additive effects of stimulus quality and richness were observed for the targeted dimensions. Our results suggest that semantic feedback does not typically reach earlier levels of representation in lexical decision, and further reinforces the idea that task context modulates the processing dynamics of early word recognition processes.

Dissociating the semantic function of two neighbouring subregions in the left lateral anterior temporal lobe

PubMed Central

Sanjuán, Ana; Hope, Thomas M.H.; Parker Jones, 'Ōiwi; Prejawa, Susan; Oberhuber, Marion; Guerin, Julie; Seghier, Mohamed L.; Green, David W.; Price, Cathy J.

2015-01-01

We used fMRI in 35 healthy participants to investigate how two neighbouring subregions in the lateral anterior temporal lobe (LATL) contribute to semantic matching and object naming. Four different levels of processing were considered: (A) recognition of the object concepts; (B) search for semantic associations related to object stimuli; (C) retrieval of semantic concepts of interest; and (D) retrieval of stimulus specific concepts as required for naming. During semantic association matching on picture stimuli or heard object names, we found that activation in both subregions was higher when the objects were semantically related (mug–kettle) than unrelated (car–teapot). This is consistent with both LATL subregions playing a role in (C), the successful retrieval of amodal semantic concepts. In addition, one subregion was more activated for object naming than matching semantically related objects, consistent with (D), the retrieval of a specific concept for naming. We discuss the implications of these novel findings for cognitive models of semantic processing and left anterior temporal lobe function. PMID:25496810

Causal Evidence for a Mechanism of Semantic Integration in the Angular Gyrus as Revealed by High-Definition Transcranial Direct Current Stimulation

PubMed Central

Peelle, Jonathan E.; Bonner, Michael F.; Grossman, Murray

2016-01-01

A defining aspect of human cognition is the ability to integrate conceptual information into complex semantic combinations. For example, we can comprehend “plaid” and “jacket” as individual concepts, but we can also effortlessly combine these concepts to form the semantic representation of “plaid jacket.” Many neuroanatomic models of semantic memory propose that heteromodal cortical hubs integrate distributed semantic features into coherent representations. However, little work has specifically examined these proposed integrative mechanisms and the causal role of these regions in semantic integration. Here, we test the hypothesis that the angular gyrus (AG) is critical for integrating semantic information by applying high-definition transcranial direct current stimulation (tDCS) to an fMRI-guided region-of-interest in the left AG. We found that anodal stimulation to the left AG modulated semantic integration but had no effect on a letter-string control task. Specifically, anodal stimulation to the left AG resulted in faster comprehension of semantically meaningful combinations like “tiny radish” relative to non-meaningful combinations, such as “fast blueberry,” when compared to the effects observed during sham stimulation and stimulation to a right-hemisphere control brain region. Moreover, the size of the effect from brain stimulation correlated with the degree of semantic coherence between the word pairs. These findings demonstrate that the left AG plays a causal role in the integration of lexical-semantic information, and that high-definition tDCS to an associative cortical hub can selectively modulate integrative processes in semantic memory. SIGNIFICANCE STATEMENT A major goal of neuroscience is to understand the neural basis of behaviors that are fundamental to human intelligence. One essential behavior is the ability to integrate conceptual knowledge from semantic memory, allowing us to construct an almost unlimited number of complex concepts from a limited set of basic constituents (e.g., “leaf” and “wet” can be combined into the more complex representation “wet leaf”). Here, we present a novel approach to studying integrative processes in semantic memory by applying focal brain stimulation to a heteromodal cortical hub implicated in semantic processing. Our findings demonstrate a causal role of the left angular gyrus in lexical-semantic integration and provide motivation for novel therapeutic applications in patients with lexical-semantic deficits. PMID:27030767

Causal Evidence for a Mechanism of Semantic Integration in the Angular Gyrus as Revealed by High-Definition Transcranial Direct Current Stimulation.

PubMed

Price, Amy Rose; Peelle, Jonathan E; Bonner, Michael F; Grossman, Murray; Hamilton, Roy H

2016-03-30

A defining aspect of human cognition is the ability to integrate conceptual information into complex semantic combinations. For example, we can comprehend "plaid" and "jacket" as individual concepts, but we can also effortlessly combine these concepts to form the semantic representation of "plaid jacket." Many neuroanatomic models of semantic memory propose that heteromodal cortical hubs integrate distributed semantic features into coherent representations. However, little work has specifically examined these proposed integrative mechanisms and the causal role of these regions in semantic integration. Here, we test the hypothesis that the angular gyrus (AG) is critical for integrating semantic information by applying high-definition transcranial direct current stimulation (tDCS) to an fMRI-guided region-of-interest in the left AG. We found that anodal stimulation to the left AG modulated semantic integration but had no effect on a letter-string control task. Specifically, anodal stimulation to the left AG resulted in faster comprehension of semantically meaningful combinations like "tiny radish" relative to non-meaningful combinations, such as "fast blueberry," when compared to the effects observed during sham stimulation and stimulation to a right-hemisphere control brain region. Moreover, the size of the effect from brain stimulation correlated with the degree of semantic coherence between the word pairs. These findings demonstrate that the left AG plays a causal role in the integration of lexical-semantic information, and that high-definition tDCS to an associative cortical hub can selectively modulate integrative processes in semantic memory. A major goal of neuroscience is to understand the neural basis of behaviors that are fundamental to human intelligence. One essential behavior is the ability to integrate conceptual knowledge from semantic memory, allowing us to construct an almost unlimited number of complex concepts from a limited set of basic constituents (e.g., "leaf" and "wet" can be combined into the more complex representation "wet leaf"). Here, we present a novel approach to studying integrative processes in semantic memory by applying focal brain stimulation to a heteromodal cortical hub implicated in semantic processing. Our findings demonstrate a causal role of the left angular gyrus in lexical-semantic integration and provide motivation for novel therapeutic applications in patients with lexical-semantic deficits. Copyright © 2016 the authors 0270-6474/16/363829-10$15.00/0.

Naming unique entities in the semantic variant of primary progressive aphasia and Alzheimer's disease: Towards a better understanding of the semantic impairment.

PubMed

Montembeault, M; Brambati, S M; Joubert, S; Boukadi, M; Chapleau, M; Laforce, R Jr; Wilson, M A; Macoir, J; Rouleau, I

2017-01-27

While the semantic variant of primary progressive aphasia (svPPA) is characterized by a predominant semantic memory impairment, episodic memory impairments are the clinical hallmark of Alzheimer's disease (AD). However, AD patients also present with semantic deficits, which are more severe for semantically unique entities (e.g. a famous person) than for common concepts (e.g. a beaver). Previous studies in these patient populations have largely focused on famous-person naming. Therefore, we aimed to evaluate if these impairments also extend to other semantically unique entities such as famous places and famous logos. In this study, 13 AD patients, 9 svPPA patients, and 12 cognitively unimpaired elderly subjects (CTRL) were tested with a picture-naming test of non-unique entities (Boston Naming Test) and three experimental tests of semantically unique entities assessing naming of famous persons, places, and logos. Both clinical groups were overall more impaired at naming semantically unique entities than non-unique entities. Naming impairments in AD and svPPA extended to the other types of semantically unique entities, since a CTRL>AD>svPPA pattern was found on the performance of all naming tests. Naming famous places and famous persons appeared to be most impaired in svPPA, and both specific and general semantic knowledge for these entities were affected in these patients. Although AD patients were most significantly impaired on famous-person naming, only their specific semantic knowledge was impaired, while general knowledge was preserved. Post-hoc neuroimaging analyses also showed that famous-person naming impairments in AD correlated with atrophy in the temporo-parietal junction, a region functionally associated with lexical access. In line with previous studies, svPPA patients' impairment in both naming and semantic knowledge suggest a more profound semantic impairment, while naming impairments in AD may arise to a greater extent from impaired lexical access, even though semantic impairment for specific knowledge is also present. These results highlight the critical importance of developing and using a variety of semantically-unique-entity naming tests in neuropsychological assessments of patients with neurodegenerative diseases, which may unveil different patterns of lexical-semantic deficits. Copyright © 2016 Elsevier Ltd. All rights reserved.

Neural dynamics of speech act comprehension: an MEG study of naming and requesting.

PubMed

Egorova, Natalia; Pulvermüller, Friedemann; Shtyrov, Yury

2014-05-01

The neurobiological basis and temporal dynamics of communicative language processing pose important yet unresolved questions. It has previously been suggested that comprehension of the communicative function of an utterance, i.e. the so-called speech act, is supported by an ensemble of neural networks, comprising lexico-semantic, action and mirror neuron as well as theory of mind circuits, all activated in concert. It has also been demonstrated that recognition of the speech act type occurs extremely rapidly. These findings however, were obtained in experiments with insufficient spatio-temporal resolution, thus possibly concealing important facets of the neural dynamics of the speech act comprehension process. Here, we used magnetoencephalography to investigate the comprehension of Naming and Request actions performed with utterances controlled for physical features, psycholinguistic properties and the probability of occurrence in variable contexts. The results show that different communicative actions are underpinned by a dynamic neural network, which differentiates between speech act types very early after the speech act onset. Within 50-90 ms, Requests engaged mirror-neuron action-comprehension systems in sensorimotor cortex, possibly for processing action knowledge and intentions. Still, within the first 200 ms of stimulus onset (100-150 ms), Naming activated brain areas involved in referential semantic retrieval. Subsequently (200-300 ms), theory of mind and mentalising circuits were activated in medial prefrontal and temporo-parietal areas, possibly indexing processing of intentions and assumptions of both communication partners. This cascade of stages of processing information about actions and intentions, referential semantics, and theory of mind may underlie dynamic and interactive speech act comprehension.

The Layer-Oriented Approach to Declarative Languages for Biological Modeling

PubMed Central

Raikov, Ivan; De Schutter, Erik

2012-01-01

We present a new approach to modeling languages for computational biology, which we call the layer-oriented approach. The approach stems from the observation that many diverse biological phenomena are described using a small set of mathematical formalisms (e.g. differential equations), while at the same time different domains and subdomains of computational biology require that models are structured according to the accepted terminology and classification of that domain. Our approach uses distinct semantic layers to represent the domain-specific biological concepts and the underlying mathematical formalisms. Additional functionality can be transparently added to the language by adding more layers. This approach is specifically concerned with declarative languages, and throughout the paper we note some of the limitations inherent to declarative approaches. The layer-oriented approach is a way to specify explicitly how high-level biological modeling concepts are mapped to a computational representation, while abstracting away details of particular programming languages and simulation environments. To illustrate this process, we define an example language for describing models of ionic currents, and use a general mathematical notation for semantic transformations to show how to generate model simulation code for various simulation environments. We use the example language to describe a Purkinje neuron model and demonstrate how the layer-oriented approach can be used for solving several practical issues of computational neuroscience model development. We discuss the advantages and limitations of the approach in comparison with other modeling language efforts in the domain of computational biology and outline some principles for extensible, flexible modeling language design. We conclude by describing in detail the semantic transformations defined for our language. PMID:22615554

The layer-oriented approach to declarative languages for biological modeling.

PubMed

Raikov, Ivan; De Schutter, Erik

2012-01-01

We present a new approach to modeling languages for computational biology, which we call the layer-oriented approach. The approach stems from the observation that many diverse biological phenomena are described using a small set of mathematical formalisms (e.g. differential equations), while at the same time different domains and subdomains of computational biology require that models are structured according to the accepted terminology and classification of that domain. Our approach uses distinct semantic layers to represent the domain-specific biological concepts and the underlying mathematical formalisms. Additional functionality can be transparently added to the language by adding more layers. This approach is specifically concerned with declarative languages, and throughout the paper we note some of the limitations inherent to declarative approaches. The layer-oriented approach is a way to specify explicitly how high-level biological modeling concepts are mapped to a computational representation, while abstracting away details of particular programming languages and simulation environments. To illustrate this process, we define an example language for describing models of ionic currents, and use a general mathematical notation for semantic transformations to show how to generate model simulation code for various simulation environments. We use the example language to describe a Purkinje neuron model and demonstrate how the layer-oriented approach can be used for solving several practical issues of computational neuroscience model development. We discuss the advantages and limitations of the approach in comparison with other modeling language efforts in the domain of computational biology and outline some principles for extensible, flexible modeling language design. We conclude by describing in detail the semantic transformations defined for our language.

Semantically Interoperable XML Data

PubMed Central

Vergara-Niedermayr, Cristobal; Wang, Fusheng; Pan, Tony; Kurc, Tahsin; Saltz, Joel

2013-01-01

XML is ubiquitously used as an information exchange platform for web-based applications in healthcare, life sciences, and many other domains. Proliferating XML data are now managed through latest native XML database technologies. XML data sources conforming to common XML schemas could be shared and integrated with syntactic interoperability. Semantic interoperability can be achieved through semantic annotations of data models using common data elements linked to concepts from ontologies. In this paper, we present a framework and software system to support the development of semantic interoperable XML based data sources that can be shared through a Grid infrastructure. We also present our work on supporting semantic validated XML data through semantic annotations for XML Schema, semantic validation and semantic authoring of XML data. We demonstrate the use of the system for a biomedical database of medical image annotations and markups. PMID:25298789

Grammatical markers switch roles and elicit different electrophysiological responses under shallow and deep semantic requirements.

PubMed

Soshi, Takahiro; Nakajima, Heizo; Hagiwara, Hiroko

2016-10-01

Static knowledge about the grammar of a natural language is represented in the cortico-subcortical system. However, the differences in dynamic verbal processing under different cognitive conditions are unclear. To clarify this, we conducted an electrophysiological experiment involving a semantic priming paradigm in which semantically congruent or incongruent word sequences (prime nouns-target verbs) were randomly presented. We examined the event-related brain potentials that occurred in response to congruent and incongruent target words that were preceded by primes with or without grammatical case markers. The two participant groups performed either the shallow (lexical judgment) or deep (direct semantic judgment) semantic tasks. We hypothesized that, irrespective of the case markers, the congruent targets would reduce centro-posterior N400 activities under the deep semantic condition, which induces selective attention to the semantic relatedness of content words. However, the same congruent targets with correct case markers would reduce lateralized negativity under the shallow semantic condition because grammatical case markers are related to automatic structural integration under semantically unattended conditions. We observed that congruent targets (e.g., 'open') that were preceded by primes with congruent case markers (e.g., 'shutter-object case') reduced lateralized negativity under the shallow semantic condition. In contrast, congruent targets, irrespective of case markers, consistently yielded N400 reductions under the deep semantic condition. To summarize, human neural verbal processing differed in response to the same grammatical markers in the same verbal expressions under semantically attended or unattended conditions.

Subliminal semantic priming in speech.

PubMed

Daltrozzo, Jérôme; Signoret, Carine; Tillmann, Barbara; Perrin, Fabien

2011-01-01

Numerous studies have reported subliminal repetition and semantic priming in the visual modality. We transferred this paradigm to the auditory modality. Prime awareness was manipulated by a reduction of sound intensity level. Uncategorized prime words (according to a post-test) were followed by semantically related, unrelated, or repeated target words (presented without intensity reduction) and participants performed a lexical decision task (LDT). Participants with slower reaction times in the LDT showed semantic priming (faster reaction times for semantically related compared to unrelated targets) and negative repetition priming (slower reaction times for repeated compared to semantically related targets). This is the first report of semantic priming in the auditory modality without conscious categorization of the prime.

Subliminal Semantic Priming in Speech

PubMed Central

Tillmann, Barbara; Perrin, Fabien

2011-01-01

Numerous studies have reported subliminal repetition and semantic priming in the visual modality. We transferred this paradigm to the auditory modality. Prime awareness was manipulated by a reduction of sound intensity level. Uncategorized prime words (according to a post-test) were followed by semantically related, unrelated, or repeated target words (presented without intensity reduction) and participants performed a lexical decision task (LDT). Participants with slower reaction times in the LDT showed semantic priming (faster reaction times for semantically related compared to unrelated targets) and negative repetition priming (slower reaction times for repeated compared to semantically related targets). This is the first report of semantic priming in the auditory modality without conscious categorization of the prime. PMID:21655277

Graph-Theoretic Properties of Networks Based on Word Association Norms: Implications for Models of Lexical Semantic Memory

ERIC Educational Resources Information Center

Gruenenfelder, Thomas M.; Recchia, Gabriel; Rubin, Tim; Jones, Michael N.

2016-01-01

We compared the ability of three different contextual models of lexical semantic memory (BEAGLE, Latent Semantic Analysis, and the Topic model) and of a simple associative model (POC) to predict the properties of semantic networks derived from word association norms. None of the semantic models were able to accurately predict all of the network…

Knowledge of the human body: a distinct semantic domain.

PubMed

Coslett, H Branch; Saffran, Eleanor M; Schwoebel, John

2002-08-13

Patients with selective deficits in the naming and comprehension of animals, plants, and artifacts have been reported. These descriptions of specific semantic category deficits have contributed substantially to the understanding of the architecture of semantic representations. This study sought to further understanding of the organization of the semantic system by demonstrating that another semantic category, knowledge of the human body, may be selectively preserved. The performance of a patient with semantic dementia was compared with the performance of healthy controls on a variety of tasks assessing distinct types of body representations, including the body schema, body image, and body structural description. Despite substantial deficits on tasks involving language and knowledge of the world generally, the patient performed normally on all tests of body knowledge except body part naming; even in this naming task, however, her performance with body parts was significantly better than on artifacts. The demonstration that body knowledge may be preserved despite substantial semantic deficits involving other types of semantic information argues that body knowledge is a distinct and dissociable semantic category. These data are interpreted as support for a model of semantics that proposes that knowledge is distributed across different cortical regions reflecting the manner in which the information was acquired.

The semantic pathfinder: using an authoring metaphor for generic multimedia indexing.

PubMed

Snoek, Cees G M; Worring, Marcel; Geusebroek, Jan-Mark; Koelma, Dennis C; Seinstra, Frank J; Smeulders, Arnold W M

2006-10-01

This paper presents the semantic pathfinder architecture for generic indexing of multimedia archives. The semantic pathfinder extracts semantic concepts from video by exploring different paths through three consecutive analysis steps, which we derive from the observation that produced video is the result of an authoring-driven process. We exploit this authoring metaphor for machine-driven understanding. The pathfinder starts with the content analysis step. In this analysis step, we follow a data-driven approach of indexing semantics. The style analysis step is the second analysis step. Here, we tackle the indexing problem by viewing a video from the perspective of production. Finally, in the context analysis step, we view semantics in context. The virtue of the semantic pathfinder is its ability to learn the best path of analysis steps on a per-concept basis. To show the generality of this novel indexing approach, we develop detectors for a lexicon of 32 concepts and we evaluate the semantic pathfinder against the 2004 NIST TRECVID video retrieval benchmark, using a news archive of 64 hours. Top ranking performance in the semantic concept detection task indicates the merit of the semantic pathfinder for generic indexing of multimedia archives.

Semantic processing during morphological priming: an ERP study.

PubMed

Beyersmann, Elisabeth; Iakimova, Galina; Ziegler, Johannes C; Colé, Pascale

2014-09-04

Previous research has yielded conflicting results regarding the onset of semantic processing during morphological priming. The present study was designed to further explore the time-course of morphological processing using event-related potentials (ERPs). We conducted a primed lexical decision study comparing a morphological (LAVAGE - laver [washing - wash]), a semantic (LINGE - laver [laundry - wash]), an orthographic (LAVANDE - laver [lavender - wash]), and an unrelated control condition (HOSPICE - laver [nursing home - wash]), using the same targets across the four priming conditions. The behavioral data showed significant effects of morphological and semantic priming, with the magnitude of morphological priming being significantly larger than the magnitude of semantic priming. The ERP data revealed significant morphological but no semantic priming at 100-250 ms. Furthermore, a reduction of the N400 amplitude in the morphological condition compared to the semantic and orthographic condition demonstrates that the morphological priming effect was not entirely due to the semantic or orthographic overlap between the prime and the target. The present data reflect an early process of semantically blind morphological decomposition, and a later process of morpho-semantic decomposition, which we discuss in the context of recent morphological processing theories. Copyright © 2014 Elsevier B.V. All rights reserved.

Semantic-based crossmodal processing during visual suppression.

PubMed

Cox, Dustin; Hong, Sang Wook

2015-01-01

To reveal the mechanisms underpinning the influence of auditory input on visual awareness, we examine, (1) whether purely semantic-based multisensory integration facilitates the access to visual awareness for familiar visual events, and (2) whether crossmodal semantic priming is the mechanism responsible for the semantic auditory influence on visual awareness. Using continuous flash suppression, we rendered dynamic and familiar visual events (e.g., a video clip of an approaching train) inaccessible to visual awareness. We manipulated the semantic auditory context of the videos by concurrently pairing them with a semantically matching soundtrack (congruent audiovisual condition), a semantically non-matching soundtrack (incongruent audiovisual condition), or with no soundtrack (neutral video-only condition). We found that participants identified the suppressed visual events significantly faster (an earlier breakup of suppression) in the congruent audiovisual condition compared to the incongruent audiovisual condition and video-only condition. However, this facilitatory influence of semantic auditory input was only observed when audiovisual stimulation co-occurred. Our results suggest that the enhanced visual processing with a semantically congruent auditory input occurs due to audiovisual crossmodal processing rather than semantic priming, which may occur even when visual information is not available to visual awareness.

Semantic framework for mapping object-oriented model to semantic web languages

PubMed Central

Ježek, Petr; Mouček, Roman

2015-01-01

The article deals with and discusses two main approaches in building semantic structures for electrophysiological metadata. It is the use of conventional data structures, repositories, and programming languages on one hand and the use of formal representations of ontologies, known from knowledge representation, such as description logics or semantic web languages on the other hand. Although knowledge engineering offers languages supporting richer semantic means of expression and technological advanced approaches, conventional data structures and repositories are still popular among developers, administrators and users because of their simplicity, overall intelligibility, and lower demands on technical equipment. The choice of conventional data resources and repositories, however, raises the question of how and where to add semantics that cannot be naturally expressed using them. As one of the possible solutions, this semantics can be added into the structures of the programming language that accesses and processes the underlying data. To support this idea we introduced a software prototype that enables its users to add semantically richer expressions into a Java object-oriented code. This approach does not burden users with additional demands on programming environment since reflective Java annotations were used as an entry for these expressions. Moreover, additional semantics need not to be written by the programmer directly to the code, but it can be collected from non-programmers using a graphic user interface. The mapping that allows the transformation of the semantically enriched Java code into the Semantic Web language OWL was proposed and implemented in a library named the Semantic Framework. This approach was validated by the integration of the Semantic Framework in the EEG/ERP Portal and by the subsequent registration of the EEG/ERP Portal in the Neuroscience Information Framework. PMID:25762923

Reproducibility and discriminability of brain patterns of semantic categories enhanced by congruent audiovisual stimuli.

PubMed

Li, Yuanqing; Wang, Guangyi; Long, Jinyi; Yu, Zhuliang; Huang, Biao; Li, Xiaojian; Yu, Tianyou; Liang, Changhong; Li, Zheng; Sun, Pei

2011-01-01

One of the central questions in cognitive neuroscience is the precise neural representation, or brain pattern, associated with a semantic category. In this study, we explored the influence of audiovisual stimuli on the brain patterns of concepts or semantic categories through a functional magnetic resonance imaging (fMRI) experiment. We used a pattern search method to extract brain patterns corresponding to two semantic categories: "old people" and "young people." These brain patterns were elicited by semantically congruent audiovisual, semantically incongruent audiovisual, unimodal visual, and unimodal auditory stimuli belonging to the two semantic categories. We calculated the reproducibility index, which measures the similarity of the patterns within the same category. We also decoded the semantic categories from these brain patterns. The decoding accuracy reflects the discriminability of the brain patterns between two categories. The results showed that both the reproducibility index of brain patterns and the decoding accuracy were significantly higher for semantically congruent audiovisual stimuli than for unimodal visual and unimodal auditory stimuli, while the semantically incongruent stimuli did not elicit brain patterns with significantly higher reproducibility index or decoding accuracy. Thus, the semantically congruent audiovisual stimuli enhanced the within-class reproducibility of brain patterns and the between-class discriminability of brain patterns, and facilitate neural representations of semantic categories or concepts. Furthermore, we analyzed the brain activity in superior temporal sulcus and middle temporal gyrus (STS/MTG). The strength of the fMRI signal and the reproducibility index were enhanced by the semantically congruent audiovisual stimuli. Our results support the use of the reproducibility index as a potential tool to supplement the fMRI signal amplitude for evaluating multimodal integration.

The role of the right hemisphere in semantic control: A case-series comparison of right and left hemisphere stroke.

PubMed

Thompson, Hannah E; Henshall, Lauren; Jefferies, Elizabeth

2016-05-01

Semantic control processes guide conceptual retrieval so that we are able to focus on non-dominant associations and features when these are required for the task or context, yet the neural basis of semantic control is not fully understood. Neuroimaging studies have emphasised the role of left inferior frontal gyrus (IFG) in controlled retrieval, while neuropsychological investigations of semantic control deficits have almost exclusively focussed on patients with left-sided damage (e.g., patients with semantic aphasia, SA). Nevertheless, activation in fMRI during demanding semantic tasks typically extends to right IFG. To investigate the role of the right hemisphere (RH) in semantic control, we compared nine RH stroke patients with 21 left-hemisphere SA patients, 11 mild SA cases and 12 healthy, aged-matched controls on semantic and executive tasks, plus experimental tasks that manipulated semantic control in paradigms particularly sensitive to RH damage. RH patients had executive deficits to parallel SA patients but they performed well on standard semantic tests. Nevertheless, multimodal semantic control deficits were found in experimental tasks involving facial emotions and the 'summation' of meaning across multiple items. On these tasks, RH patients showed effects similar to those in SA cases - multimodal deficits that were sensitive to distractor strength and cues and miscues, plus increasingly poor performance in cyclical matching tasks which repeatedly probed the same set of concepts. Thus, despite striking differences in single-item comprehension, evidence presented here suggests semantic control is bilateral, and disruption of this component of semantic cognition can be seen following damage to either hemisphere. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Reproducibility and Discriminability of Brain Patterns of Semantic Categories Enhanced by Congruent Audiovisual Stimuli

PubMed Central

Long, Jinyi; Yu, Zhuliang; Huang, Biao; Li, Xiaojian; Yu, Tianyou; Liang, Changhong; Li, Zheng; Sun, Pei

2011-01-01

One of the central questions in cognitive neuroscience is the precise neural representation, or brain pattern, associated with a semantic category. In this study, we explored the influence of audiovisual stimuli on the brain patterns of concepts or semantic categories through a functional magnetic resonance imaging (fMRI) experiment. We used a pattern search method to extract brain patterns corresponding to two semantic categories: “old people” and “young people.” These brain patterns were elicited by semantically congruent audiovisual, semantically incongruent audiovisual, unimodal visual, and unimodal auditory stimuli belonging to the two semantic categories. We calculated the reproducibility index, which measures the similarity of the patterns within the same category. We also decoded the semantic categories from these brain patterns. The decoding accuracy reflects the discriminability of the brain patterns between two categories. The results showed that both the reproducibility index of brain patterns and the decoding accuracy were significantly higher for semantically congruent audiovisual stimuli than for unimodal visual and unimodal auditory stimuli, while the semantically incongruent stimuli did not elicit brain patterns with significantly higher reproducibility index or decoding accuracy. Thus, the semantically congruent audiovisual stimuli enhanced the within-class reproducibility of brain patterns and the between-class discriminability of brain patterns, and facilitate neural representations of semantic categories or concepts. Furthermore, we analyzed the brain activity in superior temporal sulcus and middle temporal gyrus (STS/MTG). The strength of the fMRI signal and the reproducibility index were enhanced by the semantically congruent audiovisual stimuli. Our results support the use of the reproducibility index as a potential tool to supplement the fMRI signal amplitude for evaluating multimodal integration. PMID:21750692

Semantic framework for mapping object-oriented model to semantic web languages.

PubMed

Ježek, Petr; Mouček, Roman

2015-01-01

The article deals with and discusses two main approaches in building semantic structures for electrophysiological metadata. It is the use of conventional data structures, repositories, and programming languages on one hand and the use of formal representations of ontologies, known from knowledge representation, such as description logics or semantic web languages on the other hand. Although knowledge engineering offers languages supporting richer semantic means of expression and technological advanced approaches, conventional data structures and repositories are still popular among developers, administrators and users because of their simplicity, overall intelligibility, and lower demands on technical equipment. The choice of conventional data resources and repositories, however, raises the question of how and where to add semantics that cannot be naturally expressed using them. As one of the possible solutions, this semantics can be added into the structures of the programming language that accesses and processes the underlying data. To support this idea we introduced a software prototype that enables its users to add semantically richer expressions into a Java object-oriented code. This approach does not burden users with additional demands on programming environment since reflective Java annotations were used as an entry for these expressions. Moreover, additional semantics need not to be written by the programmer directly to the code, but it can be collected from non-programmers using a graphic user interface. The mapping that allows the transformation of the semantically enriched Java code into the Semantic Web language OWL was proposed and implemented in a library named the Semantic Framework. This approach was validated by the integration of the Semantic Framework in the EEG/ERP Portal and by the subsequent registration of the EEG/ERP Portal in the Neuroscience Information Framework.

Semantic e-Learning: Next Generation of e-Learning?

NASA Astrophysics Data System (ADS)

Konstantinos, Markellos; Penelope, Markellou; Giannis, Koutsonikos; Aglaia, Liopa-Tsakalidi

Semantic e-learning aspires to be the next generation of e-learning, since the understanding of learning materials and knowledge semantics allows their advanced representation, manipulation, sharing, exchange and reuse and ultimately promote efficient online experiences for users. In this context, the paper firstly explores some fundamental Semantic Web technologies and then discusses current and potential applications of these technologies in e-learning domain, namely, Semantic portals, Semantic search, personalization, recommendation systems, social software and Web 2.0 tools. Finally, it highlights future research directions and open issues of the field.

The contribution of executive control to semantic cognition: Convergent evidence from semantic aphasia and executive dysfunction.

PubMed

Thompson, Hannah E; Almaghyuli, Azizah; Noonan, Krist A; Barak, Ohr; Lambon Ralph, Matthew A; Jefferies, Elizabeth

2018-01-03

Semantic cognition, as described by the controlled semantic cognition (CSC) framework (Rogers et al., , Neuropsychologia, 76, 220), involves two key components: activation of coherent, generalizable concepts within a heteromodal 'hub' in combination with modality-specific features (spokes), and a constraining mechanism that manipulates and gates this knowledge to generate time- and task-appropriate behaviour. Executive-semantic goal representations, largely supported by executive regions such as frontal and parietal cortex, are thought to allow the generation of non-dominant aspects of knowledge when these are appropriate for the task or context. Semantic aphasia (SA) patients have executive-semantic deficits, and these are correlated with general executive impairment. If the CSC proposal is correct, patients with executive impairment should not only exhibit impaired semantic cognition, but should also show characteristics that align with those observed in SA. This possibility remains largely untested, as patients selected on the basis that they show executive impairment (i.e., with 'dysexecutive syndrome') have not been extensively tested on tasks tapping semantic control and have not been previously compared with SA cases. We explored conceptual processing in 12 patients showing symptoms consistent with dysexecutive syndrome (DYS) and 24 SA patients, using a range of multimodal semantic assessments which manipulated control demands. Patients with executive impairments, despite not being selected to show semantic impairments, nevertheless showed parallel patterns to SA cases. They showed strong effects of distractor strength, cues and miscues, and probe-target distance, plus minimal effects of word frequency on comprehension (unlike semantic dementia patients with degradation of conceptual knowledge). This supports a component process account of semantic cognition in which retrieval is shaped by control processes, and confirms that deficits in SA patients reflect difficulty controlling semantic retrieval. © 2018 The Authors. Journal of Neuropsychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

Hippocampal activation during retrieval of spatial context from episodic and semantic memory.

PubMed

Hoscheidt, Siobhan M; Nadel, Lynn; Payne, Jessica; Ryan, Lee

2010-10-15

The hippocampus, a region implicated in the processing of spatial information and episodic memory, is central to the debate concerning the relationship between episodic and semantic memory. Studies of medial temporal lobe amnesic patients provide evidence that the hippocampus is critical for the retrieval of episodic but not semantic memory. On the other hand, recent neuroimaging studies of intact individuals report hippocampal activation during retrieval of both autobiographical memories and semantic information that includes historical facts, famous faces, and categorical information, suggesting that episodic and semantic memory may engage the hippocampus during memory retrieval in similar ways. Few studies have matched episodic and semantic tasks for the degree to which they include spatial content, even though spatial content may be what drives hippocampal activation during semantic retrieval. To examine this issue, we conducted a functional magnetic resonance imaging (fMRI) study in which retrieval of spatial and nonspatial information was compared during an episodic and semantic recognition task. Results show that the hippocampus (1) participates preferentially in the retrieval of episodic memories; (2) is also engaged by retrieval of semantic memories, particularly those that include spatial information. These data suggest that sharp dissociations between episodic and semantic memory may be overly simplistic and that the hippocampus plays a role in the retrieval of spatial content whether drawn from a memory of one's own life experiences or real-world semantic knowledge. Published by Elsevier B.V.

Semantic information mediates visual attention during spoken word recognition in Chinese: Evidence from the printed-word version of the visual-world paradigm.

PubMed

Shen, Wei; Qu, Qingqing; Li, Xingshan

2016-07-01

In the present study, we investigated whether the activation of semantic information during spoken word recognition can mediate visual attention's deployment to printed Chinese words. We used a visual-world paradigm with printed words, in which participants listened to a spoken target word embedded in a neutral spoken sentence while looking at a visual display of printed words. We examined whether a semantic competitor effect could be observed in the printed-word version of the visual-world paradigm. In Experiment 1, the relationship between the spoken target words and the printed words was manipulated so that they were semantically related (a semantic competitor), phonologically related (a phonological competitor), or unrelated (distractors). We found that the probability of fixations on semantic competitors was significantly higher than that of fixations on the distractors. In Experiment 2, the orthographic similarity between the spoken target words and their semantic competitors was manipulated to further examine whether the semantic competitor effect was modulated by orthographic similarity. We found significant semantic competitor effects regardless of orthographic similarity. Our study not only reveals that semantic information can affect visual attention, it also provides important new insights into the methodology employed to investigate the semantic processing of spoken words during spoken word recognition using the printed-word version of the visual-world paradigm.

Semantic and phonological information in sentence recall: converging psycholinguistic and neuropsychological evidence.

PubMed

Schweppe, Judith; Rummer, Ralf; Bormann, Tobias; Martin, Randi C

2011-12-01

We present one experiment and a neuropsychological case study to investigate to what extent phonological and semantic representations contribute to short-term sentence recall. We modified Potter and Lombardi's (1990) intrusion paradigm, in which retention of a list interferes with sentence recall such that on the list a semantically related lure is presented, which is expected to intrude into sentence recall. In our version, lure words are either semantically related to target words in the sentence or semantically plus phonologically related. With healthy participants, intrusions are more frequent when lure and target overlap phonologically in addition to semantically than when they solely overlap semantically. When this paradigm is applied to a patient with a phonological short-term memory impairment, both lure types induce the same amount of intrusions. These findings indicate that usually phonological information is retained in sentence recall in addition to semantic information.

SemanticOrganizer: A Customizable Semantic Repository for Distributed NASA Project Teams

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Berrios, Daniel C.; Carvalho, Robert E.; Hall, David R.; Rich, Stephen J.; Sturken, Ian B.; Swanson, Keith J.; Wolfe, Shawn R.

2004-01-01

SemanticOrganizer is a collaborative knowledge management system designed to support distributed NASA projects, including diverse teams of scientists, engineers, and accident investigators. The system provides a customizable, semantically structured information repository that stores work products relevant to multiple projects of differing types. SemanticOrganizer is one of the earliest and largest semantic web applications deployed at NASA to date, and has been used in diverse contexts ranging from the investigation of Space Shuttle Columbia's accident to the search for life on other planets. Although the underlying repository employs a single unified ontology, access control and ontology customization mechanisms make the repository contents appear different for each project team. This paper describes SemanticOrganizer, its customization facilities, and a sampling of its applications. The paper also summarizes some key lessons learned from building and fielding a successful semantic web application across a wide-ranging set of domains with diverse users.

Semantic memory and depressive symptoms in patients with subjective cognitive decline, mild cognitive impairment, and Alzheimer's disease.

PubMed

Lehrner, J; Coutinho, G; Mattos, P; Moser, D; Pflüger, M; Gleiss, A; Auff, E; Dal-Bianco, P; Pusswald, G; Stögmann, E

2017-07-01

Semantic memory may be impaired in clinically recognized states of cognitive impairment. We investigated the relationship between semantic memory and depressive symptoms (DS) in patients with cognitive impairment. 323 cognitively healthy controls and 848 patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia were included. Semantic knowledge for famous faces, world capitals, and word vocabulary was investigated. Compared to healthy controls, we found a statistically significant difference of semantic knowledge in the MCI groups and the AD group, respectively. Results of the SCD group were mixed. However, two of the three semantic memory measures (world capitals and word vocabulary) showed a significant association with DS. We found a difference in semantic memory performance in MCI and AD as well as an association with DS. Results suggest that the difference in semantic memory is due to a storage loss rather than to a retrieval problem.

Localising semantic and syntactic processing in spoken and written language comprehension: an Activation Likelihood Estimation meta-analysis.

PubMed

Rodd, Jennifer M; Vitello, Sylvia; Woollams, Anna M; Adank, Patti

2015-02-01

We conducted an Activation Likelihood Estimation (ALE) meta-analysis to identify brain regions that are recruited by linguistic stimuli requiring relatively demanding semantic or syntactic processing. We included 54 functional MRI studies that explicitly varied the semantic or syntactic processing load, while holding constant demands on earlier stages of processing. We included studies that introduced a syntactic/semantic ambiguity or anomaly, used a priming manipulation that specifically reduced the load on semantic/syntactic processing, or varied the level of syntactic complexity. The results confirmed the critical role of the posterior left Inferior Frontal Gyrus (LIFG) in semantic and syntactic processing. These results challenge models of sentence comprehension highlighting the role of anterior LIFG for semantic processing. In addition, the results emphasise the posterior (but not anterior) temporal lobe for both semantic and syntactic processing. Crown Copyright © 2014. Published by Elsevier Inc. All rights reserved.

Semantic Richness and Aging: The Effect of Number of Features in the Lexical Decision Task

ERIC Educational Resources Information Center

Robert, Christelle; Rico Duarte, Liliana

2016-01-01

The aim of this study was to examine whether the effect of semantic richness in visual word recognition (i.e., words with a rich semantic representation are faster to recognize than words with a poorer semantic representation), is changed with aging. Semantic richness was investigated by manipulating the number of features of words (NOF), i.e.,…

Won't Get Fooled Again: An Event-Related Potential Study of Task and Repetition Effects on the Semantic Processing of Items without Semantics

ERIC Educational Resources Information Center

Laszlo, Sarah; Stites, Mallory; Federmeier, Kara D.

2012-01-01

A growing body of evidence suggests that semantic access is obligatory. Several studies have demonstrated that brain activity associated with semantic processing, measured in the N400 component of the event-related brain potential (ERP), is elicited even by meaningless, orthographically illegal strings, suggesting that semantic access is not gated…

The Use of a Context-Based Information Retrieval Technique

DTIC Science & Technology

2009-07-01

provided in context. Latent Semantic Analysis (LSA) is a statistical technique for inferring contextual and structural information, and previous studies...WAIS). 10 DSTO-TR-2322 1.4.4 Latent Semantic Analysis LSA, which is also known as latent semantic indexing (LSI), uses a statistical and...1.4.6 Language Models In contrast, natural language models apply algorithms that combine statistical information with semantic information. Semantic

What role does the anterior temporal lobe play in sentence-level processing? Neural correlates of syntactic processing in semantic variant primary progressive aphasia.

PubMed

Wilson, Stephen M; DeMarco, Andrew T; Henry, Maya L; Gesierich, Benno; Babiak, Miranda; Mandelli, Maria Luisa; Miller, Bruce L; Gorno-Tempini, Maria Luisa

2014-05-01

Neuroimaging and neuropsychological studies have implicated the anterior temporal lobe (ATL) in sentence-level processing, with syntactic structure-building and/or combinatorial semantic processing suggested as possible roles. A potential challenge to the view that the ATL is involved in syntactic aspects of sentence processing comes from the clinical syndrome of semantic variant primary progressive aphasia (semantic PPA; also known as semantic dementia). In semantic PPA, bilateral neurodegeneration of the ATLs is associated with profound lexical semantic deficits, yet syntax is strikingly spared. The goal of this study was to investigate the neural correlates of syntactic processing in semantic PPA to determine which regions normally involved in syntactic processing are damaged in semantic PPA and whether spared syntactic processing depends on preserved functionality of intact regions, preserved functionality of atrophic regions, or compensatory functional reorganization. We scanned 20 individuals with semantic PPA and 24 age-matched controls using structural MRI and fMRI. Participants performed a sentence comprehension task that emphasized syntactic processing and minimized lexical semantic demands. We found that, in controls, left inferior frontal and left posterior temporal regions were modulated by syntactic processing, whereas anterior temporal regions were not significantly modulated. In the semantic PPA group, atrophy was most severe in the ATLs but extended to the posterior temporal regions involved in syntactic processing. Functional activity for syntactic processing was broadly similar in patients and controls; in particular, whole-brain analyses revealed no significant differences between patients and controls in the regions modulated by syntactic processing. The atrophic left ATL did show abnormal functionality in semantic PPA patients; however, this took the unexpected form of a failure to deactivate. Taken together, our findings indicate that spared syntactic processing in semantic PPA depends on preserved functionality of structurally intact left frontal regions and moderately atrophic left posterior temporal regions, but no functional reorganization was apparent as a consequence of anterior temporal atrophy and dysfunction. These results suggest that the role of the ATL in sentence processing is less likely to relate to syntactic structure-building and more likely to relate to higher-level processes such as combinatorial semantic processing.

The analysis of professional competencies of a lecturer in adult education.

PubMed

Žeravíková, Iveta; Tirpáková, Anna; Markechová, Dagmar

2015-01-01

In this article, we present the andragogical research project and evaluation of its results using nonparametric statistical methods and the semantic differential method. The presented research was realized in the years 2012-2013 in the dissertation of I. Žeravíková: Analysis of professional competencies of lecturer and creating his competence profile (Žeravíková 2013), and its purpose was based on the analysis of work activities of a lecturer to identify his most important professional competencies and to create a suggestion of competence profile of a lecturer in adult education.

Self-others perception in a clinical sample of obese women.

PubMed

Molinari, E; Riva, G

1995-06-01

The purpose of this research, using correspondence analysis on responses to semantic differential scores, was both to examine self-perception in a clinical sample of 120 obese women and to compare this with their attitudes toward obese, thin, and normal persons. Analyses allow us to conclude that, if obese women, as reported previously, consider obesity as a largely negative condition, they have an ambivalent attitude towards themselves. Even though they share the negative connotations socially attributed to obesity, emotionally these obese women not only tend not to recognize their "abnormality" but strongly desire it.

Lesion correlates of patholinguistic profiles in chronic aphasia: comparisons of syndrome-, modality- and symptom-level assessment.

PubMed

Henseler, Ilona; Regenbrecht, Frank; Obrig, Hellmuth

2014-03-01

One way to investigate the neuronal underpinnings of language competence is to correlate patholinguistic profiles of aphasic patients to corresponding lesion sites. Constituting the beginnings of aphasiology and neurolinguistics over a century ago, this approach has been revived and refined in the past decade by statistical approaches mapping continuous variables (providing metrics that are not simply categorical) on voxel-wise lesion information (voxel-based lesion-symptom mapping). Here we investigate whether and how voxel-based lesion-symptom mapping allows us to delineate specific lesion patterns for differentially fine-grained clinical classifications. The latter encompass 'classical' syndrome-based approaches (e.g. Broca's aphasia), more symptom-oriented descriptions (e.g. agrammatism) and further refinement to linguistic sub-functions (e.g. lexico-semantic deficits for inanimate versus animate items). From a large database of patients treated for aphasia of different aetiologies (n = 1167) a carefully selected group of 102 first ever ischaemic stroke patients with chronic aphasia (∅ 12 months) were included in a VLSM analysis. Specifically, we investigated how performance in the Aachen Aphasia Test-the standard clinical test battery for chronic aphasia in German-relates to distinct brain lesions. The Aachen Aphasia Test evaluates aphasia on different levels: a non-parametric discriminant procedure yields probabilities for the allocation to one of the four 'standard' syndromes (Broca, Wernicke, global and amnestic aphasia), whereas standardized subtests target linguistic modalities (e.g. repetition), or even more specific symptoms (e.g. phoneme repetition). Because some subtests of the Aachen Aphasia Test (e.g. for the linguistic level of lexico-semantics) rely on rather coarse and heterogeneous test items we complemented the analysis with a number of more detailed clinically used tests in selected mostly mildly affected subgroups of patients. Our results indicate that: (i) Aachen Aphasia Test-based syndrome allocation allows for an unexpectedly concise differentiation between 'Broca's' and 'Wernicke's' aphasia corresponding to non-overlapping anterior and posterior lesion sites; whereas (ii) analyses for modalities and specific symptoms yielded more circumscribed but partially overlapping lesion foci, often cutting across the above syndrome territories; and (iii) especially for lexico-semantic capacities more specialized clinical test-batteries are required to delineate precise lesion patterns at this linguistic level. In sum this is the first report on a successful lesion-delineation of syndrome-based aphasia classification highlighting the relevance of vascular distribution for the syndrome level while confirming and extending a number of more linguistically motivated differentiations, based on clinically used tests. We consider such a comprehensive view reaching from the syndrome to a fine-grained symptom-oriented assessment mandatory to converge neurolinguistic, patholinguistic and clinical-therapeutic knowledge on language-competence and impairment.

Semantic knowledge fractionations: verbal propositions vs. perceptual input? Evidence from a child with Klinefelter syndrome.

PubMed

Robinson, Sally J; Temple, Christine M

2013-04-01

This paper addresses the relative independence of different types of lexical- and factually-based semantic knowledge in JM, a 9-year-old boy with Klinefelter syndrome (KS). JM was matched to typically developing (TD) controls on the basis of chronological age. Lexical-semantic knowledge was investigated for common noun (CN) and mathematical vocabulary items (MV). Factually-based semantic knowledge was investigated for general and number facts. For CN items, JM's lexical stores were of a normal size but the volume of correct 'sensory feature' semantic knowledge he generated within verbal item descriptions was significantly reduced. He was also significantly impaired at naming item descriptions and pictures, particularly for fruit and vegetables. There was also weak object decision for fruit and vegetables. In contrast, for MV items, JM's lexical stores were elevated, with no significant difference in the amount and type of correct semantic knowledge generated within verbal item descriptions and normal naming. JM's fact retrieval accuracy was normal for all types of factual knowledge. JM's performance indicated a dissociation between the representation of CN and MV vocabulary items during development. JM's preserved semantic knowledge of facts in the face of impaired semantic knowledge of vocabulary also suggests that factually-based semantic knowledge representation is not dependent on normal lexical-semantic knowledge during development. These findings are discussed in relation to the emergence of distinct semantic knowledge representations during development, due to differing degrees of dependency upon the acquisition and representation of semantic knowledge from verbal propositions and perceptual input.

When fruits lose to animals: Disorganized search of semantic memory in Parkinson's disease.

PubMed

Tagini, Sofia; Seyed-Allaei, Shima; Scarpina, Federica; Toraldo, Alessio; Mauro, Alessandro; Cherubini, Paolo; Reverberi, Carlo

2018-04-16

The semantic fluency task is widely used in both clinical and research settings to assess both the integrity of the semantic store and the effectiveness of the search through it. Our aim was to investigate whether nondemented Parkinson's disease (PD) patients show an impairment in the strategic exploration of the semantic store and whether the tested semantic category has an impact on multiple measures of performance. We compared 74 nondemented PD patients with 254 healthy subjects in a semantic fluency test using relatively small (fruits) and large (animals) semantic categories. Number of words produced, number of explored semantic subcategories, and degree of order in the produced sequences were computed as dependent variables. PD patients produced fewer words than healthy subjects did, regardless of the category. Number of subcategories was also lower in PD patients than in healthy subjects, without a significant difference between categories. Critically, PD patients' sequences were less semantically organized than were those of controls, but this effect appeared in only the smaller category (fruits), thus pointing to a lack of strategy in exploring the semantic store. Our results show that the semantic fluency deficit in PD patients has a strategic component, even though that may not be the only cause of the impaired performance. Furthermore, our evidence suggests that the semantic category used in the test influences performance, hence providing an explanation for the failure by previous studies, which often used large categories such as animals, to detect strategy deficits in PD. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

The inferior, anterior temporal lobes and semantic memory clarified: novel evidence from distortion-corrected fMRI.

PubMed

Visser, M; Embleton, K V; Jefferies, E; Parker, G J; Ralph, M A Lambon

2010-05-01

The neural basis of semantic memory generates considerable debate. Semantic dementia results from bilateral anterior temporal lobe (ATL) atrophy and gives rise to a highly specific impairment of semantic memory, suggesting that this region is a critical neural substrate for semantic processing. Recent rTMS experiments with neurologically-intact participants also indicate that the ATL are a necessary substrate for semantic memory. Exactly which regions within the ATL are important for semantic memory are difficult to detect from these methods (because the damage in SD covers a large part of the ATL). Functional neuroimaging might provide important clues about which specific areas exhibit activation that correlates with normal semantic performance. Neuroimaging studies, however, have not consistently found anterior temporal lobe activation in semantic tasks. A recent meta-analysis indicates that this inconsistency may be due to a collection of technical limitations associated with previous studies, including a reduced field-of-view and magnetic susceptibility artefacts associated with standard gradient echo fMRI. We conducted an fMRI study of semantic memory using a combination of techniques which improve sensitivity to ATL activations whilst preserving whole-brain coverage. As expected from SD patients and ATL rTMS experiments, this method revealed bilateral temporal activation extending from the inferior temporal lobe along the fusiform gyrus to the anterior temporal regions, bilaterally. We suggest that the inferior, anterior temporal lobe region makes a crucial contribution to semantic cognition and utilising this version of fMRI will enable further research on the semantic role of the ATL. 2010 Elsevier Ltd. All rights reserved.

Modelling Metamorphism by Abstract Interpretation

NASA Astrophysics Data System (ADS)

Dalla Preda, Mila; Giacobazzi, Roberto; Debray, Saumya; Coogan, Kevin; Townsend, Gregg M.

Metamorphic malware apply semantics-preserving transformations to their own code in order to foil detection systems based on signature matching. In this paper we consider the problem of automatically extract metamorphic signatures from these malware. We introduce a semantics for self-modifying code, later called phase semantics, and prove its correctness by showing that it is an abstract interpretation of the standard trace semantics. Phase semantics precisely models the metamorphic code behavior by providing a set of traces of programs which correspond to the possible evolutions of the metamorphic code during execution. We show that metamorphic signatures can be automatically extracted by abstract interpretation of the phase semantics, and that regular metamorphism can be modelled as finite state automata abstraction of the phase semantics.

A Tri-network Model of Human Semantic Processing

PubMed Central

Xu, Yangwen; He, Yong; Bi, Yanchao

2017-01-01

Humans process the meaning of the world via both verbal and nonverbal modalities. It has been established that widely distributed cortical regions are involved in semantic processing, yet the global wiring pattern of this brain system has not been considered in the current neurocognitive semantic models. We review evidence from the brain-network perspective, which shows that the semantic system is topologically segregated into three brain modules. Revisiting previous region-based evidence in light of these new network findings, we postulate that these three modules support multimodal experiential representation, language-supported representation, and semantic control. A tri-network neurocognitive model of semantic processing is proposed, which generates new hypotheses regarding the network basis of different types of semantic processes. PMID:28955266

SSWAP: A Simple Semantic Web Architecture and Protocol for semantic web services.

PubMed

Gessler, Damian D G; Schiltz, Gary S; May, Greg D; Avraham, Shulamit; Town, Christopher D; Grant, David; Nelson, Rex T

2009-09-23

SSWAP (Simple Semantic Web Architecture and Protocol; pronounced "swap") is an architecture, protocol, and platform for using reasoning to semantically integrate heterogeneous disparate data and services on the web. SSWAP was developed as a hybrid semantic web services technology to overcome limitations found in both pure web service technologies and pure semantic web technologies. There are currently over 2400 resources published in SSWAP. Approximately two dozen are custom-written services for QTL (Quantitative Trait Loci) and mapping data for legumes and grasses (grains). The remaining are wrappers to Nucleic Acids Research Database and Web Server entries. As an architecture, SSWAP establishes how clients (users of data, services, and ontologies), providers (suppliers of data, services, and ontologies), and discovery servers (semantic search engines) interact to allow for the description, querying, discovery, invocation, and response of semantic web services. As a protocol, SSWAP provides the vocabulary and semantics to allow clients, providers, and discovery servers to engage in semantic web services. The protocol is based on the W3C-sanctioned first-order description logic language OWL DL. As an open source platform, a discovery server running at http://sswap.info (as in to "swap info") uses the description logic reasoner Pellet to integrate semantic resources. The platform hosts an interactive guide to the protocol at http://sswap.info/protocol.jsp, developer tools at http://sswap.info/developer.jsp, and a portal to third-party ontologies at http://sswapmeet.sswap.info (a "swap meet"). SSWAP addresses the three basic requirements of a semantic web services architecture (i.e., a common syntax, shared semantic, and semantic discovery) while addressing three technology limitations common in distributed service systems: i.e., i) the fatal mutability of traditional interfaces, ii) the rigidity and fragility of static subsumption hierarchies, and iii) the confounding of content, structure, and presentation. SSWAP is novel by establishing the concept of a canonical yet mutable OWL DL graph that allows data and service providers to describe their resources, to allow discovery servers to offer semantically rich search engines, to allow clients to discover and invoke those resources, and to allow providers to respond with semantically tagged data. SSWAP allows for a mix-and-match of terms from both new and legacy third-party ontologies in these graphs.

Insights from child development on the relationship between episodic and semantic memory.

PubMed

Robertson, Erin K; Köhler, Stefan

2007-11-05

The present study was motivated by a recent controversy in the neuropsychological literature on semantic dementia as to whether episodic encoding requires semantic processing or whether it can proceed solely based on perceptual processing. We addressed this issue by examining the effect of age-related limitations in semantic competency on episodic memory in 4-6-year-old children (n=67). We administered three different forced-choice recognition memory tests for pictures previously encountered in a single study episode. The tests varied in the degree to which access to semantically encoded information was required at retrieval. Semantic competency predicted recognition performance regardless of whether access to semantic information was required. A direct relation between picture naming at encoding and subsequent recognition was also found for all tests. Our findings emphasize the importance of semantic encoding processes even in retrieval situations that purportedly do not require access to semantic information. They also highlight the importance of testing neuropsychological models of memory in different populations, healthy and brain damaged, at both ends of the developmental continuum.

The effects of associative and semantic priming in the lexical decision task.

PubMed

Perea, Manuel; Rosa, Eva

2002-08-01

Four lexical decision experiments were conducted to examine under which conditions automatic semantic priming effects can be obtained. Experiments 1 and 2 analyzed associative/semantic effects at several very short stimulus-onset asynchronies (SOAs), whereas Experiments 3 and 4 used a single-presentation paradigm at two response-stimulus intervals (RSIs). Experiment 1 tested associatively related pairs from three semantic categories (synonyms, antonyms, and category coordinates). The results showed reliable associative priming effects at all SOAs. In addition, the correlation between associative strength and magnitude of priming was significant only at the shortest SOA (66 ms). When prime-target pairs were semantically but not associatively related (Experiment 2), reliable priming effects were obtained at SOAs of 83 ms and longer. Using the single-presentation paradigm with a short RSI (200 ms, Experiment 3), the priming effect was equal in size for associative + semantic and for semantic-only pairs (a 21-ms effect). When the RSI was set much longer (1,750 ms, Experiment 4), only the associative + semantic pairs showed a reliable priming effect (23 ms). The results are interpreted in the context of models of semantic memory.

Investigating Correlation between Protein Sequence Similarity and Semantic Similarity Using Gene Ontology Annotations.

PubMed

Ikram, Najmul; Qadir, Muhammad Abdul; Afzal, Muhammad Tanvir

2018-01-01

Sequence similarity is a commonly used measure to compare proteins. With the increasing use of ontologies, semantic (function) similarity is getting importance. The correlation between these measures has been applied in the evaluation of new semantic similarity methods, and in protein function prediction. In this research, we investigate the relationship between the two similarity methods. The results suggest absence of a strong correlation between sequence and semantic similarities. There is a large number of proteins with low sequence similarity and high semantic similarity. We observe that Pearson's correlation coefficient is not sufficient to explain the nature of this relationship. Interestingly, the term semantic similarity values above 0 and below 1 do not seem to play a role in improving the correlation. That is, the correlation coefficient depends only on the number of common GO terms in proteins under comparison, and the semantic similarity measurement method does not influence it. Semantic similarity and sequence similarity have a distinct behavior. These findings are of significant effect for future works on protein comparison, and will help understand the semantic similarity between proteins in a better way.

Semantic Processing Impairment in Patients with Temporal Lobe Epilepsy

PubMed Central

Jaimes-Bautista, Amanda G.; Rodríguez-Camacho, Mario; Martínez-Juárez, Iris E.; Rodríguez-Agudelo, Yaneth

2015-01-01

The impairment in episodic memory system is the best-known cognitive deficit in patients with temporal lobe epilepsy (TLE). Recent studies have shown evidence of semantic disorders, but they have been less studied than episodic memory. The semantic dysfunction in TLE has various cognitive manifestations, such as the presence of language disorders characterized by defects in naming, verbal fluency, or remote semantic information retrieval, which affects the ability of patients to interact with their surroundings. This paper is a review of recent research about the consequences of TLE on semantic processing, considering neuropsychological, electrophysiological, and neuroimaging findings, as well as the functional role of the hippocampus in semantic processing. The evidence from these studies shows disturbance of semantic memory in patients with TLE and supports the theory of declarative memory of the hippocampus. Functional neuroimaging studies show an inefficient compensatory functional reorganization of semantic networks and electrophysiological studies show a lack of N400 effect that could indicate that the deficit in semantic processing in patients with TLE could be due to a failure in the mechanisms of automatic access to lexicon. PMID:26257956

The special status of verbal knowledge in semantic memory: evidence from performance of semantically impaired subjects on verbalizable and non-verbalizable versions of the object decision task.

PubMed

Zannino, Gian Daniele; Perri, Roberta; Monaco, Marco; Caltagirone, Carlo; Luzzi, Simona; Carlesimo, Giovanni A

2014-01-01

According to the semantic hub hypothesis, a supramodal semantic hub is equally needed to deal with verbal and extraverbal "surface" representations. Damage to the supramodal hub is thought to underlie the crossmodal impairment observed in selective semantic deficits. In the present paper, we provide evidence supporting an alternative view: we hold that semantic impairment is not equal across domains but affects verbal behavior disproportionately. We investigated our hypothesis by manipulating the verbal load in an object decision task. Two pathological groups showing different levels of semantic impairment were enrolled together with their normal controls. The severe group included 10 subjects with semantic dementia and the mild group 10 subjects with Alzheimer's disease. In keeping with our hypothesis, when shifting from the low verbal load to the high verbal load condition, brain-damaged individuals, as compared to controls, showed a disproportionate impairment as a function of the severity of their semantic deficit. Copyright © 2013 Elsevier Inc. All rights reserved.

Biomedical semantics in the Semantic Web

PubMed Central

2011-01-01

The Semantic Web offers an ideal platform for representing and linking biomedical information, which is a prerequisite for the development and application of analytical tools to address problems in data-intensive areas such as systems biology and translational medicine. As for any new paradigm, the adoption of the Semantic Web offers opportunities and poses questions and challenges to the life sciences scientific community: which technologies in the Semantic Web stack will be more beneficial for the life sciences? Is biomedical information too complex to benefit from simple interlinked representations? What are the implications of adopting a new paradigm for knowledge representation? What are the incentives for the adoption of the Semantic Web, and who are the facilitators? Is there going to be a Semantic Web revolution in the life sciences? We report here a few reflections on these questions, following discussions at the SWAT4LS (Semantic Web Applications and Tools for Life Sciences) workshop series, of which this Journal of Biomedical Semantics special issue presents selected papers from the 2009 edition, held in Amsterdam on November 20th. PMID:21388570

Trust estimation of the semantic web using semantic web clustering

NASA Astrophysics Data System (ADS)

Shirgahi, Hossein; Mohsenzadeh, Mehran; Haj Seyyed Javadi, Hamid

2017-05-01

Development of semantic web and social network is undeniable in the Internet world these days. Widespread nature of semantic web has been very challenging to assess the trust in this field. In recent years, extensive researches have been done to estimate the trust of semantic web. Since trust of semantic web is a multidimensional problem, in this paper, we used parameters of social network authority, the value of pages links authority and semantic authority to assess the trust. Due to the large space of semantic network, we considered the problem scope to the clusters of semantic subnetworks and obtained the trust of each cluster elements as local and calculated the trust of outside resources according to their local trusts and trust of clusters to each other. According to the experimental result, the proposed method shows more than 79% Fscore that is about 11.9% in average more than Eigen, Tidal and centralised trust methods. Mean of error in this proposed method is 12.936, that is 9.75% in average less than Eigen and Tidal trust methods.

Biomedical semantics in the Semantic Web.

PubMed

Splendiani, Andrea; Burger, Albert; Paschke, Adrian; Romano, Paolo; Marshall, M Scott

2011-03-07

The Semantic Web offers an ideal platform for representing and linking biomedical information, which is a prerequisite for the development and application of analytical tools to address problems in data-intensive areas such as systems biology and translational medicine. As for any new paradigm, the adoption of the Semantic Web offers opportunities and poses questions and challenges to the life sciences scientific community: which technologies in the Semantic Web stack will be more beneficial for the life sciences? Is biomedical information too complex to benefit from simple interlinked representations? What are the implications of adopting a new paradigm for knowledge representation? What are the incentives for the adoption of the Semantic Web, and who are the facilitators? Is there going to be a Semantic Web revolution in the life sciences?We report here a few reflections on these questions, following discussions at the SWAT4LS (Semantic Web Applications and Tools for Life Sciences) workshop series, of which this Journal of Biomedical Semantics special issue presents selected papers from the 2009 edition, held in Amsterdam on November 20th.

Language experience differentiates prefrontal and subcortical activation of the cognitive control network in novel word learning

PubMed Central

King, Kelly E.; Hernandez, Arturo E.

2012-01-01

The purpose of this study was to examine the cognitive control mechanisms in adult English speaking monolinguals compared to early sequential Spanish-English bilinguals during the initial stages of novel word learning. Functional magnetic resonance imaging during a lexico-semantic task after only two hours of exposure to novel German vocabulary flashcards showed that monolinguals activated a broader set of cortical control regions associated with higher-level cognitive processes, including the supplementary motor area (SMA), anterior cingulate (ACC), and dorsolateral prefrontal cortex (DLPFC), as well as the caudate, implicated in cognitive control of language. However, bilinguals recruited a more localized subcortical network that included the putamen, associated more with motor control of language. These results suggest that experience managing multiple languages may differentiate the learning strategy and subsequent neural mechanisms of cognitive control used by bilinguals compared to monolinguals in the early stages of novel word learning. PMID:23194816

Basic Sciences Fertilizing Clinical Microbiology and Infection Management.

PubMed

Baquero, Fernando

2017-08-15

Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of "practice deconstruction" might reveal basic questions, as in de-differentiation of tissue cells. Basic sciences, microbiology, infectious diseases, and public health constitute an epistemological gradient that should also be an investigational continuum. The coexistence of all these interests and their cross-fertilization should be favored by interdisciplinary, integrative research organizations working simultaneously in the analytical and synthetic dimensions of scientific knowledge. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

Brain responses differ to faces of mothers and fathers.

PubMed

Arsalidou, Marie; Barbeau, Emmanuel J; Bayless, Sarah J; Taylor, Margot J

2010-10-01

We encounter many faces each day but relatively few are personally familiar. Once faces are familiar, they evoke semantic and social information known about the person. Neuroimaging studies demonstrate differential brain activity to familiar and non-familiar faces; however, brain responses related to personally familiar faces have been more rarely studied. We examined brain activity with fMRI in adults in response to faces of their mothers and fathers compared to faces of celebrities and strangers. Overall, faces of mothers elicited more activity in core and extended brain regions associated with face processing, compared to fathers, celebrity or stranger faces. Fathers' faces elicited activity in the caudate, a deep brain structure associated with feelings of love. These new findings of differential brain responses elicited by faces of mothers and fathers are consistent with psychological research on attachment, evident even during adulthood. 2010 Elsevier Inc. All rights reserved.

On developing a knowledge base in infancy.

PubMed

Mandler, J M; McDonough, L

1998-11-01

The development of conceptual categories from 7 to 11 months of age was explored in 5 experiments using an object-examination task. Infants in this age range categorized the global domains of animals, vehicles, and furniture. Plants and kitchen utensils were tested at 11 months, and these domains were also categorized. When 9-month-olds were tested on kitchen utensils, they did not categorize them. Subdivisions within the animal and furniture domains were also examined. Infants did not show any subcategorization of furniture. In the animal domain both 9- and 11-month-olds responded to the life-form distinction between dogs and birds, but they did not differentiate the mammal categories of dogs and cats until 11 months. This early organization of the conceptual system into global domains that become increasingly differentiated is discussed in relation to the adult conceptual system and its breakdown in semantic dementia.

How Semantic Radicals in Chinese characters Facilitate Hierarchical Category-Based Induction.

PubMed

Wang, Xiaoxi; Ma, Xie; Tao, Yun; Tao, Yachen; Li, Hong

2018-04-03

Prior studies indicate that the semantic radical in Chinese characters contains category information that can support the independent retrieval of category information through the lexical network to the conceptual network. Inductive reasoning relies on category information; thus, semantic radicals may influence inductive reasoning. As most natural concepts are hierarchically structured in the human brain, this study examined how semantic radicals impact inductive reasoning for hierarchical concepts. The study used animal and plant nouns, organized in basic, superordinate, and subordinate levels; half had a semantic radical and half did not. Eighteen participants completed an inductive reasoning task. Behavioural and event-related potential (ERP) data were collected. The behavioural results showed that participants reacted faster and more accurately in the with-semantic-radical condition than in the without-semantic-radical condition. For the ERPs, differences between the conditions were found, and these differences lasted from the very early cognitive processing stage (i.e., the N1 time window) to the relatively late processing stages (i.e., the N400 and LPC time windows). Semantic radicals can help to distinguish the hierarchies earlier (in the N400 period) than characters without a semantic radical (in the LPC period). These results provide electrophysiological evidence that semantic radicals may improve sensitivity to distinguish between hierarchical concepts.

Somatotopic Semantic Priming and Prediction in the Motor System

PubMed Central

Grisoni, Luigi; Dreyer, Felix R.; Pulvermüller, Friedemann

2016-01-01

The recognition of action-related sounds and words activates motor regions, reflecting the semantic grounding of these symbols in action information; in addition, motor cortex exerts causal influences on sound perception and language comprehension. However, proponents of classic symbolic theories still dispute the role of modality-preferential systems such as the motor cortex in the semantic processing of meaningful stimuli. To clarify whether the motor system carries semantic processes, we investigated neurophysiological indexes of semantic relationships between action-related sounds and words. Event-related potentials revealed that action-related words produced significantly larger stimulus-evoked (Mismatch Negativity-like) and predictive brain responses (Readiness Potentials) when presented in body-part-incongruent sound contexts (e.g., “kiss” in footstep sound context; “kick” in whistle context) than in body-part-congruent contexts, a pattern reminiscent of neurophysiological correlates of semantic priming. Cortical generators of the semantic relatedness effect were localized in areas traditionally associated with semantic memory, including left inferior frontal cortex and temporal pole, and, crucially, in motor areas, where body-part congruency of action sound–word relationships was indexed by a somatotopic pattern of activation. As our results show neurophysiological manifestations of action-semantic priming in the motor cortex, they prove semantic processing in the motor system and thus in a modality-preferential system of the human brain. PMID:26908635

Auditing Associative Relations across Two Knowledge Sources

PubMed Central

Vizenor, Lowell T.; Bodenreider, Olivier; McCray, Alexa T.

2009-01-01

Objectives This paper proposes a novel semantic method for auditing associative relations in biomedical terminologies. We tested our methodology on two Unified Medical Language System (UMLS) knowledge sources. Methods We use the UMLS semantic groups as high-level representations of the domain and range of relationships in the Metathesaurus and in the Semantic Network. A mapping created between Metathesaurus relationships and Semantic Network relationships forms the basis for comparing the signatures of a given Metathesaurus relationship to the signatures of the semantic relationship to which it is mapped. The consistency of Metathesaurus relations is studied for each relationship. Results Of the 177 associative relationships in the Metathesaurus, 84 (48%) exhibit a high degree of consistency with the corresponding Semantic Network relationships. Overall, 63% of the 1.8M associative relations in the Metathesaurus are consistent with relations in the Semantic Network. Conclusion The semantics of associative relationships in biomedical terminologies should be defined explicitly by their developers. The Semantic Network would benefit from being extended with new relationships and with new relations for some existing relationships. The UMLS editing environment could take advantage of the correspondence established between relationships in the Metathesaurus and the Semantic Network. Finally, the auditing method also yielded useful information for refining the mapping of associative relationships between the two sources. PMID:19475724