Sample records for separate functional units

  1. Passive dendrites enable single neurons to compute linearly non-separable functions.

    PubMed

    Cazé, Romain Daniel; Humphries, Mark; Gutkin, Boris

    2013-01-01

    Local supra-linear summation of excitatory inputs occurring in pyramidal cell dendrites, the so-called dendritic spikes, results in independent spiking dendritic sub-units, which turn pyramidal neurons into two-layer neural networks capable of computing linearly non-separable functions, such as the exclusive OR. Other neuron classes, such as interneurons, may possess only a few independent dendritic sub-units, or only passive dendrites where input summation is purely sub-linear, and where dendritic sub-units are only saturating. To determine if such neurons can also compute linearly non-separable functions, we enumerate, for a given parameter range, the Boolean functions implementable by a binary neuron model with a linear sub-unit and either a single spiking or a saturating dendritic sub-unit. We then analytically generalize these numerical results to an arbitrary number of non-linear sub-units. First, we show that a single non-linear dendritic sub-unit, in addition to the somatic non-linearity, is sufficient to compute linearly non-separable functions. Second, we analytically prove that, with a sufficient number of saturating dendritic sub-units, a neuron can compute all functions computable with purely excitatory inputs. Third, we show that these linearly non-separable functions can be implemented with at least two strategies: one where a dendritic sub-unit is sufficient to trigger a somatic spike; another where somatic spiking requires the cooperation of multiple dendritic sub-units. We formally prove that implementing the latter architecture is possible with both types of dendritic sub-units whereas the former is only possible with spiking dendrites. Finally, we show how linearly non-separable functions can be computed by a generic two-compartment biophysical model and a realistic neuron model of the cerebellar stellate cell interneuron. Taken together our results demonstrate that passive dendrites are sufficient to enable neurons to compute linearly non-separable functions.

  2. Passive Dendrites Enable Single Neurons to Compute Linearly Non-separable Functions

    PubMed Central

    Cazé, Romain Daniel; Humphries, Mark; Gutkin, Boris

    2013-01-01

    Local supra-linear summation of excitatory inputs occurring in pyramidal cell dendrites, the so-called dendritic spikes, results in independent spiking dendritic sub-units, which turn pyramidal neurons into two-layer neural networks capable of computing linearly non-separable functions, such as the exclusive OR. Other neuron classes, such as interneurons, may possess only a few independent dendritic sub-units, or only passive dendrites where input summation is purely sub-linear, and where dendritic sub-units are only saturating. To determine if such neurons can also compute linearly non-separable functions, we enumerate, for a given parameter range, the Boolean functions implementable by a binary neuron model with a linear sub-unit and either a single spiking or a saturating dendritic sub-unit. We then analytically generalize these numerical results to an arbitrary number of non-linear sub-units. First, we show that a single non-linear dendritic sub-unit, in addition to the somatic non-linearity, is sufficient to compute linearly non-separable functions. Second, we analytically prove that, with a sufficient number of saturating dendritic sub-units, a neuron can compute all functions computable with purely excitatory inputs. Third, we show that these linearly non-separable functions can be implemented with at least two strategies: one where a dendritic sub-unit is sufficient to trigger a somatic spike; another where somatic spiking requires the cooperation of multiple dendritic sub-units. We formally prove that implementing the latter architecture is possible with both types of dendritic sub-units whereas the former is only possible with spiking dendrites. Finally, we show how linearly non-separable functions can be computed by a generic two-compartment biophysical model and a realistic neuron model of the cerebellar stellate cell interneuron. Taken together our results demonstrate that passive dendrites are sufficient to enable neurons to compute linearly non-separable functions. PMID:23468600

  3. Increased Mechanical Cost of Walking in Children with Diplegia: The Role of the Passenger Unit Cannot Be Neglected

    ERIC Educational Resources Information Center

    Van de Walle, P.; Hallemans, A.; Truijen, S.; Gosselink, R.; Heyrman, L.; Molenaers, G.; Desloovere, K.

    2012-01-01

    Gait efficiency in children with cerebral palsy is decreased. To date, most research did not include the upper body as a separate functional unit when exploring these changes in gait efficiency. Since children with spastic diplegia often experience problems with trunk control, they could benefit from separate evaluation of the so-called "passenger…

  4. Unsupervised segmentation with dynamical units.

    PubMed

    Rao, A Ravishankar; Cecchi, Guillermo A; Peck, Charles C; Kozloski, James R

    2008-01-01

    In this paper, we present a novel network to separate mixtures of inputs that have been previously learned. A significant capability of the network is that it segments the components of each input object that most contribute to its classification. The network consists of amplitude-phase units that can synchronize their dynamics, so that separation is determined by the amplitude of units in an output layer, and segmentation by phase similarity between input and output layer units. Learning is unsupervised and based on a Hebbian update, and the architecture is very simple. Moreover, efficient segmentation can be achieved even when there is considerable superposition of the inputs. The network dynamics are derived from an objective function that rewards sparse coding in the generalized amplitude-phase variables. We argue that this objective function can provide a possible formal interpretation of the binding problem and that the implementation of the network architecture and dynamics is biologically plausible.

  5. Examining the Effects of Mexican Serial Migration and Family Separations on Acculturative Stress, Depression, and Family Functioning

    ERIC Educational Resources Information Center

    Rusch, Dana; Reyes, Karina

    2013-01-01

    This study examined the role of parent-child separations during serial migration to the United States in predicting individual- and family-level outcomes in Mexican immigrant families. We assessed parents' subjective appraisals of their family's separation and reunion experiences to explore associations with self-reported acculturative stress,…

  6. The American Civil-Military Relationship: A Delicate Balance

    DTIC Science & Technology

    2008-01-01

    important Constitutional safeguards consistent with the separation of powers . The power to control appropriations to the national military...existence of a functional Constitution system prevented the emerging standing army from wresting control of the United States through the separation of powers . A

  7. Data processing for water monitoring system

    NASA Technical Reports Server (NTRS)

    Monford, L.; Linton, A. T.

    1978-01-01

    Water monitoring data acquisition system is structured about central computer that controls sampling and sensor operation, and analyzes and displays data in real time. Unit is essentially separated into two systems: computer system, and hard wire backup system which may function separately or with computer.

  8. Liquid/Gas Separator Handles Varying Loads

    NASA Technical Reports Server (NTRS)

    Mann, John

    1992-01-01

    Liquid/gas separator includes two independent motors, one for pumping mixture and other for drawing off extracted gas. Two materials moved at speeds best suited for them. Liquid expelled radially outward from separator rotor. Entrained gas released, flows axially through rotor, and leaves through fan at downstream end. Unit developed to separate air from urine in spacecraft wastewater-treatment system, also functions in normal gravity. Made largely of titanium to resist corrosion.

  9. Assessment of Severity of Ovine Smoke Inhalation Injury by Analysis of Computed Tomographic Scans

    DTIC Science & Technology

    2003-09-01

    Computerized analysis of three- dimensional reconstructed scans was also performed, based on Hounsfield unit ranges: hyperinflated, 1,000 to 900; normal...the interactive segmentation function of the software. The pulmonary parenchyma was separated into four regions based on the Hounsfield unit (HU...SII) severity. Methods: Twenty anesthetized sheep underwent graded SII: group I, no smoke; group II, 5 smoke units ; group III, 10 units ; and group IV

  10. HAL/S-FC compiler system functional specification

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The functional requirements to be met by the HAL/S-FC compiler, and the hardware and software compatibilities between the compiler system and the environment in which it operates are defined. Associated runtime facilities and the interface with the Software Development Laboratory are specified. The construction of the HAL/S-FC system as functionally separate units and the interfaces between those units is described. An overview of the system's capabilities is presented and the hardware/operating system requirements are specified. The computer-dependent aspects of the HAL/S-FC are also specified. Compiler directives are included.

  11. The Work of the Television Journalist.

    ERIC Educational Resources Information Center

    Tyrrell, Robert

    This book describes the various functions of the television journalist--in the United States and Great Britain--and supplies knowledge enabling members of a television team to work successfully as a unit. Separate chapters are devoted to discussions of (1) the world of television journalism, (2) writing for television, (3) the role of the…

  12. 20 CFR 1.6 - How were many of OWCP's current functions administered in the past?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF LABOR ORGANIZATION AND PROCEDURES PERFORMANCE OF FUNCTIONS § 1.6 How were many of OWCP's... shall deem appropriate, authorizing the performance of any of his functions by any other officer, agency, or employee of the DOL. (b) In 1972, two separate organizational units were established within the...

  13. Separation of cells from the rat anterior pituitary gland

    NASA Technical Reports Server (NTRS)

    Hymer, W. C.; Hatfield, J. Michael

    1984-01-01

    Data concerned with analyzing the cellular organization of the rat anterior pituitary gland are examined. The preparation of the cell suspensions and the methods used to separate pituitary cell types are described. Particular emphasis is given to velocity sedimentation at unit gravity, density gradient centrifugation, affinity methods, fluorescence activated cell sorting, and density gradient and continuous-flow electrophoresis. The difficulties encountered when attempting to compare data from different pituitary cell separation studies are discussed, and results from various experiments are presented. The functional capabilities of the separated cell populations can be tested in various culture systems.

  14. Complex Processes from Dynamical Architectures with Time-Scale Hierarchy

    PubMed Central

    Perdikis, Dionysios; Huys, Raoul; Jirsa, Viktor

    2011-01-01

    The idea that complex motor, perceptual, and cognitive behaviors are composed of smaller units, which are somehow brought into a meaningful relation, permeates the biological and life sciences. However, no principled framework defining the constituent elementary processes has been developed to this date. Consequently, functional configurations (or architectures) relating elementary processes and external influences are mostly piecemeal formulations suitable to particular instances only. Here, we develop a general dynamical framework for distinct functional architectures characterized by the time-scale separation of their constituents and evaluate their efficiency. Thereto, we build on the (phase) flow of a system, which prescribes the temporal evolution of its state variables. The phase flow topology allows for the unambiguous classification of qualitatively distinct processes, which we consider to represent the functional units or modes within the dynamical architecture. Using the example of a composite movement we illustrate how different architectures can be characterized by their degree of time scale separation between the internal elements of the architecture (i.e. the functional modes) and external interventions. We reveal a tradeoff of the interactions between internal and external influences, which offers a theoretical justification for the efficient composition of complex processes out of non-trivial elementary processes or functional modes. PMID:21347363

  15. Operationalizing Army Cyber

    DTIC Science & Technology

    2013-03-01

    killed just under 3,000 people and cost the U.S. economy somewhere between three and five trillion dollars. The Japanese attacked with a state... economy , and military readiness. The challenge is to design an Army Cyber force that can support the United States Cyber Command (USCYBERCOM) national...still keeps the intelligence and signal functions separate in most units today from battalion to echelon above Corps ( EAC ). There are many past reasons

  16. Methods for calculating forest ecosystem and harvested carbon with standard estimates for forest types of the United States

    Treesearch

    James E. Smith; Linda S. Heath; Kenneth E. Skog; Richard A. Birdsey

    2006-01-01

    This study presents techniques for calculating average net annual additions to carbon in forests and in forest products. Forest ecosystem carbon yield tables, representing stand-level merchantable volume and carbon pools as a function of stand age, were developed for 51 forest types within 10 regions of the United States. Separate tables were developed for...

  17. Translanguaging in the Borderlands: Language Function in Theatre for Young Audiences Written in Spanish and English in the United States

    ERIC Educational Resources Information Center

    Schildkret, Elizabeth

    2017-01-01

    In the United States, we tend to understand linguistic systems as separate and autonomous, and by this understanding, bilinguals are people who speak two different languages and switch between them. This understanding of bilingualism, however, does not reflect the reality of the way many bilinguals use language. Rather than "code-switch"…

  18. Design and Parameter Study of Integrated Microfluidic Platform for CTC Isolation and Enquiry; A Numerical Approach.

    PubMed

    Shamloo, Amir; Ahmad, Saba; Momeni, Maede

    2018-06-18

    Being the second cause of mortality across the globe, there is now a persistent effort to establish new cancer medication and therapies. Any accomplishment in treating cancers entails the existence of accurate identification systems empowering the early diagnosis. Recent studies indicate CTCs’ potential in cancer prognosis as well as therapy monitoring. The chief shortcoming with CTCs is that they are exceedingly rare cells in their clinically relevant concentration. Here, we simulated a microfluidic construct devised for immunomagnetic separation of the particles of interest from the background cells. This separation unit is integrated with a mixer subunit. The mixer is envisioned for mixing the CTC enriched stream with lysis buffer to extract the biological material of the cell. Some modification was proposed on mixing geometry improving the efficacy of the functional unit. A valuation of engaged forces was made and some forces were neglected due to their order of magnitude. The position of the magnet was also optimized by doing parametric study. For the mixer unit, the effect of applied voltage and frequency on mixing index was studied to find the optimal voltage and frequency which provides better mixing. Above-mentioned studies were done on isolated units and the effect of each functional unit on the other is not studied. As the final step, an integrated microfluidic platform composed of both functional subunits was simulated simultaneously. To ensure the independence of results from the grid, grid studies were also performed. The studies carried out on the construct reveal its potential for diagnostic application.

  19. Fabrication technology: A compilation

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A compilation is presented which supplies technical information on the assembly of diverse components into functional assemblies and subassemblies, as well as information on several fasteners and fastening techniques that join components, subassemblies, and complete assemblies to achieve a functional unit. Quick-disconnect fasteners are described, along with several devices and methods for attaching thermal insulators, and for joining and separating objects in the absence of gravity.

  20. SIM PlanetQuest Spectral Calibration Development Unit Beam Combiner

    NASA Technical Reports Server (NTRS)

    Tang, Hong

    2008-01-01

    The beam combiner of an astronomical long-baseline interferometer combines the two beams of starlight to form white-light fringes. We describe beam combiner in the SIM PlanetQuest Spectral Calibration Development Unit (SCDU). In addition to forming white light fringes, the beam combiner provides other functions such as separating the light for guiding, fringe tracking, and science measurement. It is designed to function over the optical bandpass 450-950 nm. Coating design is critical to beam combiner as residual dispersion and mismatches affect the ability to accurately measure the position of stars of varying spectral types.

  1. Nano-optical conveyor belt, part I: Theory.

    PubMed

    Hansen, Paul; Zheng, Yuxin; Ryan, Jason; Hesselink, Lambertus

    2014-06-11

    We propose a method for peristaltic transport of nanoparticles using the optical force field over a nanostructured surface. Nanostructures may be designed to produce strong near-field hot spots when illuminated. The hot spots function as optical traps, separately addressable by their resonant wavelengths and polarizations. By activating closely packed traps sequentially, nanoparticles may be handed off between adjacent traps in a peristaltic fashion. A linear repeating structure of three separately addressable traps forms a "nano-optical conveyor belt"; a unit cell with four separately addressable traps permits controlled peristaltic transport in the plane. Using specifically designed activation sequences allows particle sorting.

  2. Combustion systems and power plants incorporating parallel carbon dioxide capture and sweep-based membrane separation units to remove carbon dioxide from combustion gases

    DOEpatents

    Wijmans, Johannes G [Menlo Park, CA; Merkel, Timothy C [Menlo Park, CA; Baker, Richard W [Palo Alto, CA

    2011-10-11

    Disclosed herein are combustion systems and power plants that incorporate sweep-based membrane separation units to remove carbon dioxide from combustion gases. In its most basic embodiment, the invention is a combustion system that includes three discrete units: a combustion unit, a carbon dioxide capture unit, and a sweep-based membrane separation unit. In a preferred embodiment, the invention is a power plant including a combustion unit, a power generation system, a carbon dioxide capture unit, and a sweep-based membrane separation unit. In both of these embodiments, the carbon dioxide capture unit and the sweep-based membrane separation unit are configured to be operated in parallel, by which we mean that each unit is adapted to receive exhaust gases from the combustion unit without such gases first passing through the other unit.

  3. Optimizing management of the condensing heat and cooling of gases compression in oxy block using of a genetic algorithm

    NASA Astrophysics Data System (ADS)

    Brzęczek, Mateusz; Bartela, Łukasz

    2013-12-01

    This paper presents the parameters of the reference oxy combustion block operating with supercritical steam parameters, equipped with an air separation unit and a carbon dioxide capture and compression installation. The possibility to recover the heat in the analyzed power plant is discussed. The decision variables and the thermodynamic functions for the optimization algorithm were identified. The principles of operation of genetic algorithm and methodology of conducted calculations are presented. The sensitivity analysis was performed for the best solutions to determine the effects of the selected variables on the power and efficiency of the unit. Optimization of the heat recovery from the air separation unit, flue gas condition and CO2 capture and compression installation using genetic algorithm was designed to replace the low-pressure section of the regenerative water heaters of steam cycle in analyzed unit. The result was to increase the power and efficiency of the entire power plant.

  4. 26 CFR 1.1503-2 - Dual consolidated loss.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... tiers of separate units. If a separate unit of a domestic corporation is owned indirectly through... upper-tier separate unit were a subsidiary of the domestic corporation and the lower-tier separate unit were a lower-tier subsidiary. (4) Examples. The following examples illustrate the application of this...

  5. Airspace Complexity and its Application in Air Traffic Management

    NASA Technical Reports Server (NTRS)

    Sridhar, Banavar; Chatterji, Gano; Sheth, Kapil; Edwards, Thomas (Technical Monitor)

    1998-01-01

    The United States Air Traffic Management (ATM) system provides services to enable safe, orderly and efficient aircraft operations within the airspace over the continental United States and over large portions of the Pacific and Atlantic Oceans, and the Gulf of Mexico. It consists of two components, Air Traffic Control (ATC) and Traffic Flow Management (TFM). The ATC function ensures that the aircraft within the airspace are separated at all times while the TFM function organizes the aircraft into a flow pattern to ensure their safe and efficient movement. In order to accomplish the ATC and TFM functions, the airspace over United States is organized into 22 Air Route Traffic Control Centers (ARTCCs). The Center airspace is stratified into low-altitude, high-altitude and super-high altitude groups of Sectors. Each vertical layer is further partitioned into several horizontal Sectors. A typical ARTCC airspace is partitioned into 20 to 80 Sectors. These Sectors are the basic control units within the ATM system.

  6. Functional role of oligomerization for bacterial and plant SWEET sugar transporter family.

    PubMed

    Xuan, Yuan Hu; Hu, Yi Bing; Chen, Li-Qing; Sosso, Davide; Ducat, Daniel C; Hou, Bi-Huei; Frommer, Wolf B

    2013-09-24

    Eukaryotic sugar transporters of the MFS and SWEET superfamilies consist of 12 and 7 α-helical transmembrane domains (TMs), respectively. Structural analyses indicate that MFS transporters evolved from a series of tandem duplications of an ancestral 3-TM unit. SWEETs are heptahelical proteins carrying a tandem repeat of 3-TM separated by a single TM. Here, we show that prokaryotes have ancestral SWEET homologs with only 3-TM and that the Bradyrhizobium japonicum SemiSWEET1, like Arabidopsis SWEET11, mediates sucrose transport. Eukaryotic SWEETs most likely evolved by internal duplication of the 3-TM, suggesting that SemiSWEETs form oligomers to create a functional pore. However, it remains elusive whether the 7-TM SWEETs are the functional unit or require oligomerization to form a pore sufficiently large to allow for sucrose passage. Split ubiquitin yeast two-hybrid and split GFP assays indicate that Arabidopsis SWEETs homo- and heterooligomerize. We examined mutant SWEET variants for negative dominance to test if oligomerization is necessary for function. Mutation of the conserved Y57 or G58 in SWEET1 led to loss of activity. Coexpression of the defective mutants with functional A. thaliana SWEET1 inhibited glucose transport, indicating that homooligomerization is necessary for function. Collectively, these data imply that the basic unit of SWEETs, similar to MFS sugar transporters, is a 3-TM unit and that a functional transporter contains at least four such domains. We hypothesize that the functional unit of the SWEET family of transporters possesses a structure resembling the 12-TM MFS structure, however, with a parallel orientation of the 3-TM unit.

  7. Functional role of oligomerization for bacterial and plant SWEET sugar transporter family

    PubMed Central

    Xuan, Yuan Hu; Hu, Yi Bing; Chen, Li-Qing; Sosso, Davide; Ducat, Daniel C.; Hou, Bi-Huei; Frommer, Wolf B.

    2013-01-01

    Eukaryotic sugar transporters of the MFS and SWEET superfamilies consist of 12 and 7 α-helical transmembrane domains (TMs), respectively. Structural analyses indicate that MFS transporters evolved from a series of tandem duplications of an ancestral 3-TM unit. SWEETs are heptahelical proteins carrying a tandem repeat of 3-TM separated by a single TM. Here, we show that prokaryotes have ancestral SWEET homologs with only 3-TM and that the Bradyrhizobium japonicum SemiSWEET1, like Arabidopsis SWEET11, mediates sucrose transport. Eukaryotic SWEETs most likely evolved by internal duplication of the 3-TM, suggesting that SemiSWEETs form oligomers to create a functional pore. However, it remains elusive whether the 7-TM SWEETs are the functional unit or require oligomerization to form a pore sufficiently large to allow for sucrose passage. Split ubiquitin yeast two-hybrid and split GFP assays indicate that Arabidopsis SWEETs homo- and heterooligomerize. We examined mutant SWEET variants for negative dominance to test if oligomerization is necessary for function. Mutation of the conserved Y57 or G58 in SWEET1 led to loss of activity. Coexpression of the defective mutants with functional A. thaliana SWEET1 inhibited glucose transport, indicating that homooligomerization is necessary for function. Collectively, these data imply that the basic unit of SWEETs, similar to MFS sugar transporters, is a 3-TM unit and that a functional transporter contains at least four such domains. We hypothesize that the functional unit of the SWEET family of transporters possesses a structure resembling the 12-TM MFS structure, however, with a parallel orientation of the 3-TM unit. PMID:24027245

  8. The evolution and function of protein tandem repeats in plants.

    PubMed

    Schaper, Elke; Anisimova, Maria

    2015-04-01

    Sequence tandem repeats (TRs) are abundant in proteomes across all domains of life. For plants, little is known about their distribution or contribution to protein function. We exhaustively annotated TRs and studied the evolution of TR unit variations for all Ensembl plants. Using phylogenetic patterns of TR units, we detected conserved TRs with unit number and order preserved during evolution, and those TRs that have diverged via recent TR unit gains/losses. We correlated the mode of evolution of TRs to protein function. TR number was strongly correlated with proteome size, with about one-half of all TRs recognized as common protein domains. The majority of TRs have been highly conserved over long evolutionary distances, some since the separation of red algae and green plants c. 1.6 billion yr ago. Conversely, recurrent recent TR unit mutations were rare. Our results suggest that the first TRs by far predate the first plants, and that TR appearance is an ongoing process with similar rates across the plant kingdom. Interestingly, the few detected highly mutable TRs might provide a source of variation for rapid adaptation. In particular, such TRs are enriched in leucine-rich repeats (LRRs) commonly found in R genes, where TR unit gain/loss may facilitate resistance to emerging pathogens. © 2014 The Authors. New Phytologist © 2014 New Phytologist Trust.

  9. Gas Permeation Computations with Mathematica

    ERIC Educational Resources Information Center

    Binous, Housam

    2006-01-01

    We show a new approach, based on the utilization of Mathematica, to solve gas permeation problems using membranes. We start with the design of a membrane unit for the separation of a multicomponent mixture. The built-in Mathematica function, FindRoot, allows one to solve seven simultaneous equations instead of using the iterative approach of…

  10. Exploration of Public Service Occupations. Curriculum Guide.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Div. of Vocational Education.

    The guide contains the basic concepts and instructional materials recommended for the exploration of public service occupations at the junior high school level (grades 7-9). The materials can be used as a separate course or can be integrated into the subject areas suggested. The 17 units deal with the functioning of Federal, State, and local…

  11. Gender Segregation: Separate but Effective?

    ERIC Educational Resources Information Center

    Holthouse, David

    2010-01-01

    In 2002, only 11 public schools in the United States had gender-segregated classrooms. As of December 2009, there were more than 550. The movement is based on the hypothesis that hard-wired differences in the ways that male and female brains develop and function in childhood through adolescence require classrooms in which boys and girls are not…

  12. Carter separable electromagnetic fields

    NASA Astrophysics Data System (ADS)

    Lynden-Bell, D.

    2000-02-01

    The purely electromagnetic analogue in flat space of Kerr's metric in general relativity is only rarely considered. Here we carry out in flat space a programme similar to Carter's investigation of metrics in general relativity in which the motion of a charged particle is separable. We concentrate on the separability of the motion (be it classical, relativistic or quantum) of a charged particle in electromagnetic fields that lie in planes through an axis of symmetry. In cylindrical polar coordinates (t,R,φ,z) the four-vector potential takes the form [formmu2] is the unit toroidal vector. The forms of the functions Φ(R,z) and A(R,z) are sought that allow separable motion. This occurs for relativistic motion only when AR,Φ and A2-Φ2 are all of the separable form ζ(λ)-η(μ)]/(λ-μ), where ζ and η are arbitrary functions, and λ and μ are spheroidal coordinates or degenerations thereof. The special forms of A and Φ that allow this are deduced. They include the Kerr metric analogue, with E+iB=-∇{q[(r-ia).(r-ia)]-1/2}. Rather more general electromagnetic fields allow separation when the motion is non-relativistic. The investigation is extended to fields that lie in parallel planes. Connections to Larmor's theorem are remarked upon.

  13. A Simple Secure Hash Function Scheme Using Multiple Chaotic Maps

    NASA Astrophysics Data System (ADS)

    Ahmad, Musheer; Khurana, Shruti; Singh, Sushmita; AlSharari, Hamed D.

    2017-06-01

    The chaotic maps posses high parameter sensitivity, random-like behavior and one-way computations, which favor the construction of cryptographic hash functions. In this paper, we propose to present a novel hash function scheme which uses multiple chaotic maps to generate efficient variable-sized hash functions. The message is divided into four parts, each part is processed by a different 1D chaotic map unit yielding intermediate hash code. The four codes are concatenated to two blocks, then each block is processed through 2D chaotic map unit separately. The final hash value is generated by combining the two partial hash codes. The simulation analyses such as distribution of hashes, statistical properties of confusion and diffusion, message and key sensitivity, collision resistance and flexibility are performed. The results reveal that the proposed anticipated hash scheme is simple, efficient and holds comparable capabilities when compared with some recent chaos-based hash algorithms.

  14. Application of a hierarchical habitat unit classification system: stream habitat and salmonid distribution in Ward Creek, southeast Alaska.

    Treesearch

    M.D. Bryant; B.E. Wright; B.J. Davies

    1992-01-01

    A hierarchical classification system separating stream habitat into habitat units defined by stream morphology and hydrology was used in a pre-enhancement stream survey. The system separates habitat units into macrounits, mesounits, and micro- units and includes a separate evaluation of instream cover that also uses the hierarchical scheme. This paper presents an...

  15. Three 3D metal coordination polymers based on triazol-functionalized rigid ligand: Synthesis, topological structure and properties

    NASA Astrophysics Data System (ADS)

    Meng, Lingkun; Liu, Kang; Liang, Chen; Guo, Xiaolei; Han, Xu; Ren, Siyuan; Ma, Dingxuan; Li, Guanghua; Shi, Zhan; Feng, Shouhua

    2018-02-01

    By using a triazol-functionalized tricarboxylate, three novel metal coordination polymers, namely, [Zn2L(OH)]·0.5H2O (1), [Co2L(OH)(H2O)]·5.5H2O (2), [Cu2(HL)] (3) L = [5-(3-(4-carboxyphenyl)-5-methyl-4H-1,2,4-triazol-4-yl)isophthalate] were synthesized under hydrothermal reactions. All the compounds were characterized by element analysis, IR spectroscopy, thermogravimetric analysis, power X-ray diffrcation and single-crystal X-ray diffrcation. Structural analysis reveals that compounds 1 and 2 have 3D networks with flu topologies where rigid trizaol-functionalized ligands as 4-connected nodes and Zn4(COO)6 or Co4(COO)6 clusters serves as 8-connected secondary building units. Compound 3 has 3D network with pcu topology where Cu4(COO)4 clusters serve as 6-connected secondary building units. Gas adsorption studies reveal that desolvated compoud 1 exhibits high H2 absorption capacity at 77 K and highly selective separation abilities of CO2 and C3H8 over CH4 at room temperature. The results suggest that 1 has potential application in gas storage and separation. In addition, the magnetic properties of compound 2 were also investigated.

  16. Postreceptoral chromatic-adaptation mechanisms in the red-green and blue-yellow systems using simple reaction times

    NASA Astrophysics Data System (ADS)

    Medina, José M.; Díaz, José A.

    2006-05-01

    Simple visual-reaction times (VRT) were measured for a variety of stimuli selected along red-green (L-M axis) and blue-yellow [S-(L+M) axis] directions in the isoluminant plane under different adaptation stimuli. Data were plotted in terms of the RMS cone contrast in contrast-threshold units. For each opponent system, a modified Piéron function was fitted in each experimental configuration and on all adaptation stimuli. A single function did not account for all the data, confirming the existence of separate postreceptoral adaptation mechanisms in each opponent system under suprathreshold conditions. The analysis of the VRT-hazard functions suggested that both color-opponent mechanisms present a well-defined, transient-sustained structure at marked suprathreshold conditions. The influence of signal polarity and chromatic adaptation on each color axis proves the existence of asymmetries in the integrated hazard functions, suggesting separate detection mechanisms for each pole (red, green, blue, and yellow detectors).

  17. Evaluating the compatibility of American and Mexican national forest inventory data

    Treesearch

    Todd A. Schroeder; Sean P. Healey; Gretchen G. Moisen

    2012-01-01

    The international border region between the United States and Mexico represents a point of discontinuity in forest policy, land use management and resource utilization practices. These differences along with physical barriers which separate the two countries can interact to alter the structure and functioning of forest vegetation. One valuable source of information for...

  18. 45 CFR 302.12 - Single and separate organizational unit.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 2 2011-10-01 2011-10-01 false Single and separate organizational unit. 302.12... (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES STATE PLAN REQUIREMENTS § 302.12 Single and separate organizational unit. (a) The State...

  19. Paradox of pattern separation and adult neurogenesis: A dual role for new neurons balancing memory resolution and robustness.

    PubMed

    Johnston, Stephen T; Shtrahman, Matthew; Parylak, Sarah; Gonçalves, J Tiago; Gage, Fred H

    2016-03-01

    Hippocampal adult neurogenesis is thought to subserve pattern separation, the process by which similar patterns of neuronal inputs are transformed into distinct neuronal representations, permitting the discrimination of highly similar stimuli in hippocampus-dependent tasks. However, the mechanism by which immature adult-born dentate granule neurons cells (abDGCs) perform this function remains unknown. Two theories of abDGC function, one by which abDGCs modulate and sparsify activity in the dentate gyrus and one by which abDGCs act as autonomous coding units, are generally suggested to be mutually exclusive. This review suggests that these two mechanisms work in tandem to dynamically regulate memory resolution while avoiding memory interference and maintaining memory robustness. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Sample injection and electrophoretic separation on a simple laminated paper based analytical device.

    PubMed

    Xu, Chunxiu; Zhong, Minghua; Cai, Longfei; Zheng, Qingyu; Zhang, Xiaojun

    2016-02-01

    We described a strategy to perform multistep operations on a simple laminated paper-based separation device by using electrokinetic flow to manipulate the fluids. A laminated crossed-channel paper-based separation device was fabricated by cutting a filter paper sheet followed by lamination. Multiple function units including sample loading, sample injection, and electrophoretic separation were integrated on a single paper based analytical device for the first time, by applying potential at different reservoirs for sample, sample waste, buffer, and buffer waste. As a proof-of-concept demonstration, mixed sample solution containing carmine and sunset yellow were loaded in the sampling channel, and then injected into separation channel followed by electrophoretic separation, by adjusting the potentials applied at the four terminals of sampling and separation channel. The effects of buffer pH, buffer concentration, channel width, and separation time on resolution of electrophoretic separation were studied. This strategy may be used to perform multistep operations such as reagent dilution, sample injection, mixing, reaction, and separation on a single microfluidic paper based analytical device, which is very attractive for building micro total analysis systems on microfluidic paper based analytical devices. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Periodic activation function and a modified learning algorithm for the multivalued neuron.

    PubMed

    Aizenberg, Igor

    2010-12-01

    In this paper, we consider a new periodic activation function for the multivalued neuron (MVN). The MVN is a neuron with complex-valued weights and inputs/output, which are located on the unit circle. Although the MVN outperforms many other neurons and MVN-based neural networks have shown their high potential, the MVN still has a limited capability of learning highly nonlinear functions. A periodic activation function, which is introduced in this paper, makes it possible to learn nonlinearly separable problems and non-threshold multiple-valued functions using a single multivalued neuron. We call this neuron a multivalued neuron with a periodic activation function (MVN-P). The MVN-Ps functionality is much higher than that of the regular MVN. The MVN-P is more efficient in solving various classification problems. A learning algorithm based on the error-correction rule for the MVN-P is also presented. It is shown that a single MVN-P can easily learn and solve those benchmark classification problems that were considered unsolvable using a single neuron. It is also shown that a universal binary neuron, which can learn nonlinearly separable Boolean functions, and a regular MVN are particular cases of the MVN-P.

  2. Relaxation of Actinide Surfaces: An All Electron Study

    NASA Astrophysics Data System (ADS)

    Atta-Fynn, Raymond; Dholabhai, Pratik; Ray, Asok

    2006-10-01

    Fully relativistic full potential density functional calculations with a linearized augmented plane wave plus local orbitals basis (LAPW + lo) have been performed to investigate the relaxations of heavy actinide surfaces, namely the (111) surface of fcc δ-Pu and the (0001) surface of dhcp Am using WIEN2k. This code uses the LAPW + lo method with the unit cell divided into non-overlapping atom-centered spheres and an interstitial region. The APW+lo basis is used to describe all s, p, d, and f states and LAPW basis to describe all higher angular momentum states. Each surface was modeled by a three-layer periodic slab separated by 60 Bohr vacuum with four atoms per surface unit cell. In general, we have found a contraction of the interlayer separations for both Pu and Am. We will report, in detail, the electronic and geometric structures of the relaxed surfaces and comparisons with the respective non-relaxed surfaces.

  3. Increased mechanical cost of walking in children with diplegia: the role of the passenger unit cannot be neglected.

    PubMed

    Van de Walle, P; Hallemans, A; Truijen, S; Gosselink, R; Heyrman, L; Molenaers, G; Desloovere, K

    2012-01-01

    Gait efficiency in children with cerebral palsy is decreased. To date, most research did not include the upper body as a separate functional unit when exploring these changes in gait efficiency. Since children with spastic diplegia often experience problems with trunk control, they could benefit from separate evaluation of the so-called 'passenger unit'. Therefore, the aim of the current study was to improve insights in the role of the passenger unit in decreased gait efficiency in children with diplegia. Mechanical cost of walking was investigated by calculating work by the integrated joint power approach in 18 children with diplegia and 25 age-related typical developing controls. The total mechanical work in children with diplegia was 1.5 times higher than in typical children. In children with diplegia work at the lower limbs was increased by 37% compared to typical children. Substantially higher increases, up to 222%, were noted at the passenger unit. Trunk and head were the main contributors to the increased work of the passenger unit, but the role of the arms cannot be neglected. Due to these disproportional increases in locomotor and passenger unit, the demands of the passenger unit in pathological gait can no longer be considered minor, as in typical gait. Therefore, the role of the passenger unit must be recognized in the decrease of gait efficiency in children with spastic diplegia and should be part of the evaluation of gait efficiency in clinical practice. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Room-Temperature Synthesis of Two-Dimensional Metal–Organic Frameworks with Controllable Size and Functionality for Enhanced CO 2 Sorption

    DOE PAGES

    Zha, Jie; Zhang, Xueyi

    2018-04-17

    Here, two-dimensional (2D) metal-organic frameworks (MOFs), as a newly emerged member of 2D materials, have gained extensive attention due to their great potential in gas separation, sensing, and catalysis. However, it is still challenging to synthesize 2D MOFs with controllable size and functionalities using direct and scalable approaches at mild conditions (e.g., room temperature). Herein, we demonstrated onestep, room-temperature synthesis of a series of 2D MOFs based on Cu(II) paddle-wheel units, where the intrinsically anisotropic building blocks led to the anisotropic growth of 2D MOF nanoparticles, and the pillared structure led to high surface areas. The size of 2D MOFsmore » can be adjusted by using a DMF/H 2O mixed solvent. The thinnest particles were around 3 nm, and the highest aspect ratio was up to 200. The functionalization of 2D MOFs was also achieved by selecting ligands with desired functional groups. The gas sorption results revealed that amino and nitro-functionalized 2D MOFs showed higher CO 2 sorption selectivity over CH 4 and N 2, suggesting these materials can be further applied in natural gas sweetening (CO 2/CH 4 separation) and carbon capture from flue gas (CO 2/N 2 separation).« less

  5. Room-Temperature Synthesis of Two-Dimensional Metal–Organic Frameworks with Controllable Size and Functionality for Enhanced CO 2 Sorption

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zha, Jie; Zhang, Xueyi

    Here, two-dimensional (2D) metal-organic frameworks (MOFs), as a newly emerged member of 2D materials, have gained extensive attention due to their great potential in gas separation, sensing, and catalysis. However, it is still challenging to synthesize 2D MOFs with controllable size and functionalities using direct and scalable approaches at mild conditions (e.g., room temperature). Herein, we demonstrated onestep, room-temperature synthesis of a series of 2D MOFs based on Cu(II) paddle-wheel units, where the intrinsically anisotropic building blocks led to the anisotropic growth of 2D MOF nanoparticles, and the pillared structure led to high surface areas. The size of 2D MOFsmore » can be adjusted by using a DMF/H 2O mixed solvent. The thinnest particles were around 3 nm, and the highest aspect ratio was up to 200. The functionalization of 2D MOFs was also achieved by selecting ligands with desired functional groups. The gas sorption results revealed that amino and nitro-functionalized 2D MOFs showed higher CO 2 sorption selectivity over CH 4 and N 2, suggesting these materials can be further applied in natural gas sweetening (CO 2/CH 4 separation) and carbon capture from flue gas (CO 2/N 2 separation).« less

  6. A New Approach to Detect Mover Position in Linear Motors Using Magnetic Sensors

    PubMed Central

    Paul, Sarbajit; Chang, Junghwan

    2015-01-01

    A new method to detect the mover position of a linear motor is proposed in this paper. This method employs a simple cheap Hall Effect sensor-based magnetic sensor unit to detect the mover position of the linear motor. With the movement of the linear motor, Hall Effect sensor modules electrically separated 120° along with the idea of three phase balanced condition (va + vb + vc = 0) are used to produce three phase signals. The amplitude of the sensor output voltage signals are adjusted to unit amplitude to minimize the amplitude errors. With the unit amplitude signals three to two phase transformation is done to reduce the three multiples of harmonic components. The final output thus obtained is converted to position data by the use of arctangent function. The measurement accuracy of the new method is analyzed by experiments and compared with the conventional two phase method. Using the same number of sensor modules as the conventional two phase method, the proposed method gives more accurate position information compared to the conventional system where sensors are separated by 90° electrical angles. PMID:26506348

  7. Do fungi have a role as soil stabilizers and remediators after forest fire?

    Treesearch

    Andrew W. Claridge; James M. Trappe; Karen Hansen

    2009-01-01

    The functional roles of fungi in recovery of forest ecosystems after fire remain poorly documented. We observed macrofungi soon after fire at two widely separated sites, one in the Pacific Northwest United States and the other in southeastern mainland Australia. The range of species onsite was compared against macrofungi reported after the volcanic eruption at Mount St...

  8. Morphospaces of functionally analogous traits show ecological separation between birds and pterosaurs.

    PubMed

    Chan, Nicholas R

    2017-10-25

    Birds originated and radiated in the presence of another group of flying vertebrates, the pterosaurs. Opinion is divided as to whether birds competitively displaced pterosaurs from small-body size niches or whether the two groups coexisted with little competition. Previous studies of Mesozoic birds and pterosaurs compared measurements of homologous limb bones to test these hypotheses. However, these characters probably reflect differing ancestries rather than ecologies. Here, competition and ecological separation were tested for using multivariate analyses of functionally equivalent morphological characters. As well as using characters from the fore- and hindlimbs, these analyses also included measurements of the lower jaw. The results of this study indicate that pterosaurs had relatively longer jaws, shorter metatarsals and shorter brachial regions compared with birds of similar size. Contrary to the results of previous studies, the distal wing was not important for separating the two clades in morphospace owing to the inclusion of the primary feathers in this unit. The differences found here indicate ecological separation based on differences in size, locomotory features and feeding adaptations. Thus, instead of one group displacing the other, birds and pterosaurs appear to have adopted distinctive ecological strategies throughout their period of coexistence. © 2017 The Author(s).

  9. Fresenius AS.TEC204 blood cell separator.

    PubMed

    Sugai, Mikiya

    2003-02-01

    Fresenius AS.TEC204 is a third-generation blood cell separator that incorporates the continuous centrifugal separation method and automatic control of the cell separation process. Continuous centrifugation separates cell components according to their specific gravity, and different cell components are either harvested or eliminated as needed. The interface between the red blood cell and plasma is optically detected, and the Interface Control (IFC) cooperates with different pumps, monitors and detectors to harvest required components automatically. The system is composed of three major sections; the Front Panel Unit; the Pump Unit, and the Centrifuge Unit. This unit can be used for a wide variety of clinical applications including collection of platelets, peripheral blood stem cells, bone marrow stem cells, granulocytes, mononuclear cells, and exchange of plasma or red cells, and for plasma treatment.

  10. Improving STEM Education and Workforce Development by the Inclusion of Research Experiences in the Curriculum at SWC

    DTIC Science & Technology

    2016-06-08

    server environment. While the college’s two Cisco blade -servers are located in separate buildings, these 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND...college’s two Cisco blade -servers are located in separate buildings, these units now work as one unit. Critical databases and software packages are...server environment. While the college’s two Cisco blade -servers are located in separate buildings, these units now work as one unit. Critical

  11. Capturing ultrafast photoinduced local structural distortions of BiFeO 3

    DOE PAGES

    Wen, Haidan; Sassi, Michel JPC; Luo, Zhenlin; ...

    2015-10-14

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO 3 film. The out-of-plane elongation of the unit cell is accompanied bymore » the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This uniaxial elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated nonequilibrium processes in polar materials.« less

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wen, Haidan; Sassi, Michel; Luo, Zhenlin

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO 3 film. The out-of-plane elongation of the unit cell is accompanied bymore » the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This anisotropic elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated non-equilibrium processes in polar materials.« less

  13. Capturing ultrafast photoinduced local structural distortions of BiFeO3

    PubMed Central

    Wen, Haidan; Sassi, Michel; Luo, Zhenlin; Adamo, Carolina; Schlom, Darrell G.; Rosso, Kevin M.; Zhang, Xiaoyi

    2015-01-01

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO3 film. The out-of-plane elongation of the unit cell is accompanied by the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This anisotropic elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated non-equilibrium processes in polar materials. PMID:26463128

  14. Capturing ultrafast photoinduced local structural distortions of BiFeO3.

    PubMed

    Wen, Haidan; Sassi, Michel; Luo, Zhenlin; Adamo, Carolina; Schlom, Darrell G; Rosso, Kevin M; Zhang, Xiaoyi

    2015-10-14

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO3 film. The out-of-plane elongation of the unit cell is accompanied by the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This anisotropic elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated non-equilibrium processes in polar materials.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wen, Haidan; Sassi, Michel JPC; Luo, Zhenlin

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO 3 film. The out-of-plane elongation of the unit cell is accompanied bymore » the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This uniaxial elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated nonequilibrium processes in polar materials.« less

  16. Capturing ultrafast photoinduced local structural distortions of BiFeO3

    NASA Astrophysics Data System (ADS)

    Wen, Haidan; Sassi, Michel; Luo, Zhenlin; Adamo, Carolina; Schlom, Darrell G.; Rosso, Kevin M.; Zhang, Xiaoyi

    2015-10-01

    The interaction of light with materials is an intensively studied research forefront, in which the coupling of radiation energy to selective degrees of freedom offers contact-free tuning of functionalities on ultrafast time scales. Capturing the fundamental processes and understanding the mechanism of photoinduced structural rearrangement are essential to applications such as photo-active actuators and efficient photovoltaic devices. Using ultrafast x-ray absorption spectroscopy aided by density functional theory calculations, we reveal the local structural arrangement around the transition metal atom in a unit cell of the photoferroelectric archetype BiFeO3 film. The out-of-plane elongation of the unit cell is accompanied by the in-plane shrinkage with minimal change of interaxial lattice angles upon photoexcitation. This anisotropic elastic deformation of the unit cell is driven by localized electric field as a result of photoinduced charge separation, in contrast to a global lattice constant increase and lattice angle variations as a result of heating. The finding of a photoinduced elastic unit cell deformation elucidates a microscopic picture of photocarrier-mediated non-equilibrium processes in polar materials.

  17. Predicting Multicomponent Adsorption Isotherms in Open-Metal Site Materials Using Force Field Calculations Based on Energy Decomposed Density Functional Theory.

    PubMed

    Heinen, Jurn; Burtch, Nicholas C; Walton, Krista S; Fonseca Guerra, Célia; Dubbeldam, David

    2016-12-12

    For the design of adsorptive-separation units, knowledge is required of the multicomponent adsorption behavior. Ideal adsorbed solution theory (IAST) breaks down for olefin adsorption in open-metal site (OMS) materials due to non-ideal donor-acceptor interactions. Using a density-function-theory-based energy decomposition scheme, we develop a physically justifiable classical force field that incorporates the missing orbital interactions using an appropriate functional form. Our first-principles derived force field shows greatly improved quantitative agreement with the inflection points, initial uptake, saturation capacity, and enthalpies of adsorption obtained from our in-house adsorption experiments. While IAST fails to make accurate predictions, our improved force field model is able to correctly predict the multicomponent behavior. Our approach is also transferable to other OMS structures, allowing the accurate study of their separation performances for olefins/paraffins and further mixtures involving complex donor-acceptor interactions. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Appendix to HDC 2118 design criteria 100-X reactor water plant, general description - section II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1952-03-29

    The factors responsible for the advances of 100-X compared with the older areas are: Simplification of the process, such as elimination of separate process water clearwells, by having the filtered water reservoirs perform that function. Combination of separate buildings into one building, such as combining filter pump house and process pump house. Use of electric standby. Use of higher capacity pumps and filter basins, and so fewer number of units. Centralization of control and operation. More compact arrangement of plant components. Use of waste heat for space heating, recovered from reactor effluent, backed up by steam plant.

  19. Intra- and inter-unit variation in fly ash petrography and mercury adsorption: Examples from a western Kentucky power station

    USGS Publications Warehouse

    Hower, J.C.; Finkelman, R.B.; Rathbone, R.F.; Goodman, J.

    2000-01-01

    Fly ash was collected from eight mechanical and 10 baghouse hoppers at each of the twin 150-MW wall-fired units in a western Kentucky power station. The fuel burned at that time was a blend of many low-sulfur, high-volatile bituminous Central Appalachian coals. The baghouse ash showed less variation between units than the mechanical hoppers. The mechanical fly ash, coarser than the baghouse ash, showed significant differences in the amount of total carbon and in the ratio of isotropic coke to both total carbon and total coke - the latter excluding inertinite and other unburned, uncoked coal. There was no significant variation in proportions of inorganic fly ash constituents. The inter-unit differences in the amount and forms of mechanical fly ash carbon appear to be related to differences in pulverizer efficiency, leading to greater amounts of coarse coal, therefore unburned carbon, in one of the units. Mercury capture is a function of both the total carbon content and the gas temperature at the point of fly ash separation, mercury content increasing with an increase in carbon for a specific collection system. Mercury adsorption on fly ash carbon increases at lower flue-gas temperatures. Baghouse fly ash, collected at a lower temperature than the higher-carbon mechanically separated fly ash, contains a significantly greater amount of Hg.

  20. Annular feed air breathing fuel cell stack

    DOEpatents

    Wilson, Mahlon S.

    1996-01-01

    A stack of polymer electrolyte fuel cells is formed from a plurality of unit cells where each unit cell includes fuel cell components defining a periphery and distributed along a common axis, where the fuel cell components include a polymer electrolyte membrane, an anode and a cathode contacting opposite sides of the membrane, and fuel and oxygen flow fields contacting the anode and the cathode, respectively, wherein the components define an annular region therethrough along the axis. A fuel distribution manifold within the annular region is connected to deliver fuel to the fuel flow field in each of the unit cells. In a particular embodiment, a single bolt through the annular region clamps the unit cells together. In another embodiment, separator plates between individual unit cells have an extended radial dimension to function as cooling fins for maintaining the operating temperature of the fuel cell stack.

  1. Chitosan in Molecularly-Imprinted Polymers: Current and Future Prospects.

    PubMed

    Xu, Long; Huang, Yun-An; Zhu, Qiu-Jin; Ye, Chun

    2015-08-07

    Chitosan is widely used in molecular imprinting technology (MIT) as a functional monomer or supporting matrix because of its low cost and high contents of amino and hydroxyl functional groups. The various excellent properties of chitosan, which include nontoxicity, biodegradability, biocompatibility, and attractive physical and mechanical performances, make chitosan a promising alternative to conventional functional monomers. Recently, chitosan molecularly-imprinted polymers have gained considerable attention and showed significant potential in many fields, such as curbing environmental pollution, medicine, protein separation and identification, and chiral-compound separation. These extensive applications are due to the polymers' desired selectivity, physical robustness, and thermal stability, as well as their low cost and easy preparation. Cross-linkers, which fix the functional groups of chitosan around imprinted molecules, play an important role in chitosan molecularly-imprinted polymers. This review summarizes the important cross-linkers of chitosan molecularly-imprinted polymers and illustrates the cross-linking mechanism of chitosan and cross-linkers based on the two glucosamine units. Finally, some significant attempts to further develop the application of chitosan in MIT are proposed.

  2. Homopolymer Micelles in Heterogeneous Solvent Mixtures

    PubMed Central

    Basu, Subhadeep; Vutukuri, Dharma Rao

    2008-01-01

    Amphiphilic homopolymers containing a hydrophilic and a hydrophobic functionality in each monomer unit have been shown to form polar or apolar containers depending on the solvent environment. When presented with a mixture of solvents, these polymeric containers are capable of releasing certain guest molecules. The fundamental mechanism behind these properties is investigated and the utility of these assemblies in separations has been demonstrated with an example. PMID:16316219

  3. Automated Microfluidic Instrument for Label-Free and High-Throughput Cell Separation.

    PubMed

    Zhang, Xinjie; Zhu, Zhixian; Xiang, Nan; Long, Feifei; Ni, Zhonghua

    2018-03-20

    Microfluidic technologies for cell separation were reported frequently in recent years. However, a compact microfluidic instrument enabling thoroughly automated cell separation is still rarely reported until today due to the difficult hybrid between the macrosized fluidic control system and the microsized microfluidic device. In this work, we propose a novel and automated microfluidic instrument to realize size-based separation of cancer cells in a label-free and high-throughput manner. Briefly, the instrument is equipped with a fully integrated microfluidic device and a set of robust fluid-driven and control units, and the instrument functions of precise fluid infusion and high-throughput cell separation are guaranteed by a flow regulatory chip and two cell separation chips which are the key components of the microfluidic device. With optimized control programs, the instrument is successfully applied to automatically sort human breast adenocarcinoma cell line MCF-7 from 5 mL of diluted human blood with a high recovery ratio of ∼85% within a rapid processing time of ∼23 min. We envision that our microfluidic instrument will be potentially useful in many biomedical applications, especially cell separation, enrichment, and concentration for the purpose of cell culture and analysis.

  4. Immigration Enforcement, Parent-Child Separations, and Intent to Remigrate by Central American Deportees.

    PubMed

    Amuedo-Dorantes, Catalina; Pozo, Susan; Puttitanun, Thitima

    2015-12-01

    Given the unprecedented increase in the flow of migrants from El Salvador, Guatemala, and Honduras to the United States, this article analyzes the impact of U.S. interior enforcement on parent-child separations among Central American deportees, along with its implications for deportees' intentions to remigrate to the United States. Using the EMIF sur survey data, we find that interior enforcement raises the likelihood of parent-child separations as well as the likelihood that parents forcedly separated from their young children report the intention to return to the United States, presumably without documents. By increasing parent-child separations, interior enforcement could prove counterproductive in deterring repetitive unauthorized crossings among Central American deportees.

  5. Fame and obsolescence: Disentangling growth and aging dynamics of patent citations.

    PubMed

    Higham, K W; Governale, M; Jaffe, A B; Zülicke, U

    2017-04-01

    We present an analysis of citations accrued over time by patents granted by the United States Patent and Trademark Office in 1998. In contrast to previous studies, a disaggregation by technology category is performed, and exogenously caused citation-number growth is controlled for. Our approach reveals an intrinsic citation rate that clearly separates into an-in the long run, exponentially time-dependent-aging function and a completely time-independent preferential-attachment-type growth kernel. For the general case of such a separable citation rate, we obtain the time-dependent citation distribution analytically in a form that is valid for any functional form of its aging and growth parts. Good agreement between theory and long-time characteristics of patent-citation data establishes our work as a useful framework for addressing still open questions about knowledge-propagation dynamics, such as the observed excess of citations at short times.

  6. D Visualization of a Timber Frame Historic Building: Partite Usage and its Impact on the Structural System

    NASA Astrophysics Data System (ADS)

    Günay, S.

    2017-08-01

    Throughout their lifetime, historic buildings might be altered for different kind of usage for different purposes. If this new function or new usage requires utilization of the building in separate units, this separation might affect the historic building's functionality and structure and as a result its overall condition. Yorguc Pasa Mansion conservation project was prepared as a part of the Middle East Technical University (METU) Master's Program in Documentation and Conservation of Historic Monuments and Sites for the historic Yorguc Pasa Mansion. The mansion is a 19th century Ottoman Period timber frame building in Amasya, a Black Sea Region city in Turkey that has traces from different civilizations such as Hittites, Greeks, Romans and Ottomans. This paper aims to discuss the affects of the partite usage on structural conditions of timber frame buildings with the case study of Amasya Yorguc Pasa Mansion through the 3D visualized structural systems.

  7. Fame and obsolescence: Disentangling growth and aging dynamics of patent citations

    NASA Astrophysics Data System (ADS)

    Higham, K. W.; Governale, M.; Jaffe, A. B.; Zülicke, U.

    2017-04-01

    We present an analysis of citations accrued over time by patents granted by the United States Patent and Trademark Office in 1998. In contrast to previous studies, a disaggregation by technology category is performed, and exogenously caused citation-number growth is controlled for. Our approach reveals an intrinsic citation rate that clearly separates into an—in the long run, exponentially time-dependent—aging function and a completely time-independent preferential-attachment-type growth kernel. For the general case of such a separable citation rate, we obtain the time-dependent citation distribution analytically in a form that is valid for any functional form of its aging and growth parts. Good agreement between theory and long-time characteristics of patent-citation data establishes our work as a useful framework for addressing still open questions about knowledge-propagation dynamics, such as the observed excess of citations at short times.

  8. Mapping magnetized geologic structures from space: The effect of orbital and body parameters

    NASA Technical Reports Server (NTRS)

    Schnetzler, C. C.; Taylor, P. T.; Langel, R. A.

    1984-01-01

    When comparing previous satellite magnetometer missions (such as MAGSAT) with proposed new programs (for example, Geopotential Research Mission, GRM) it is important to quantify the difference in scientific information obtained. The ability to resolve separate magnetic blocks (simulating geological units) is used as a parameter for evaluating the expected geologic information from each mission. The effect of satellite orbital altitude on the ability to resolve two magnetic blocks with varying separations is evaluated and quantified. A systematic, nonlinear, relationship exists between resolution and distance between magnetic blocks as a function of orbital altitude. The proposed GRM would provide an order-of-magnitude greater anomaly resolution than the earlier MAGSAT mission for widely separated bodies. The resolution achieved at any particular altitude varies depending on the location of the bodies and orientation.

  9. Use of a Ceramic Membrane to Improve the Performance of Two-Separate-Phase Biocatalytic Membrane Reactor.

    PubMed

    Ranieri, Giuseppe; Mazzei, Rosalinda; Wu, Zhentao; Li, Kang; Giorno, Lidietta

    2016-03-14

    Biocatalytic membrane reactors (BMR) combining reaction and separation within the same unit have many advantages over conventional reactor designs. Ceramic membranes are an attractive alternative to polymeric membranes in membrane biotechnology due to their high chemical, thermal and mechanical resistance. Another important use is their potential application in a biphasic membrane system, where support solvent resistance is highly needed. In this work, the preparation of asymmetric ceramic hollow fibre membranes and their use in a two-separate-phase biocatalytic membrane reactor will be described. The asymmetric ceramic hollow fibre membranes were prepared using a combined phase inversion and sintering technique. The prepared fibres were then used as support for lipase covalent immobilization in order to develop a two-separate-phase biocatalytic membrane reactor. A functionalization method was proposed in order to increase the density of the reactive hydroxyl groups on the surface of ceramic membranes, which were then amino-activated and treated with a crosslinker. The performance and the stability of the immobilized lipase were investigated as a function of the amount of the immobilized biocatalytst. Results showed that it is possible to immobilize lipase on a ceramic membrane without altering its catalytic performance (initial residual specific activity 93%), which remains constant after 6 reaction cycles.

  10. 26 CFR 1.985-3 - United States dollar approximate separate transactions method.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... transactions method. 1.985-3 Section 1.985-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... dollar approximate separate transactions method. (a) Scope and effective date—(1) Scope. This section describes the United States dollar (dollar) approximate separate transactions method of accounting (DASTM...

  11. Bioinspired Organic PV Cells Using Photosynthetic Pigment Complex for Energy Harvesting Materials

    DTIC Science & Technology

    2010-05-10

    ultrafast laser spectroscopy. More recently the structures of the LH2 complexes has revealed the nonameric or octameric arrangement of repeating units...Scheme 1. Compartimentalization of light harvesting and charge separation. The antenna complexes( LH2 ,LH1-RC) efficiently realize various...photosynthetic functions using cofactors (BChl a and carotenoid) assembled into the apoproteins (LH1 and LH2 ). The light-harvesting mechanisms in these

  12. Space Shuttle Orbiter auxiliary power unit status

    NASA Technical Reports Server (NTRS)

    Reck, M.; Loken, G.; Horton, J.; Lukens, W.; Scott, W.; Baughman, J.; Bauch, T.

    1991-01-01

    An overview of the United States Space Shuttle Orbiter APU, which provides power to the Orbiter vehicle hydraulic system, is presented. Three complete APU systems, each with its own separate fuel system, supply power to three dedicated hydraulic systems. These in turn provide power to all Orbiter vehicle critical flight functions including launch, orbit, reentry, and landing. The basic APU logic diagram is presented. The APU includes a hydrazine-powered turbine that drives a hydraulic pump and various accessories through a high-speed gearbox. The APU also features a sophisticated thermal management system designed to ensure safe and reliable operation in the various launch, orbit, reentry, and landing environments.

  13. Expression of 5 S rRNA genes linked to 35 S rDNA in plants, their epigenetic modification and regulatory element divergence

    PubMed Central

    2012-01-01

    Background In plants, the 5 S rRNA genes usually occur as separate tandems (S-type arrangement) or, less commonly, linked to 35 S rDNA units (L-type). The activity of linked genes remains unknown so far. We studied the homogeneity and expression of 5 S genes in several species from family Asteraceae known to contain linked 35 S-5 S units. Additionally, their methylation status was determined using bisulfite sequencing. Fluorescence in situ hybridization was applied to reveal the sub-nuclear positions of rDNA arrays. Results We found that homogenization of L-type units went to completion in most (4/6) but not all species. Two species contained major L-type and minor S-type units (termed Ls-type). The linked genes dominate 5 S rDNA expression while the separate tandems do not seem to be expressed. Members of tribe Anthemideae evolved functional variants of the polymerase III promoter in which a residing C-box element differs from the canonical angiosperm motif by as much as 30%. On this basis, a more relaxed consensus sequence of a plant C-box: (5’-RGSWTGGGTG-3’) is proposed. The 5 S paralogs display heavy DNA methylation similarly as to their unlinked counterparts. FISH revealed the close association of 35 S-5 S arrays with nucleolar periphery indicating that transcription of 5 S genes may occur in this territory. Conclusions We show that the unusual linked arrangement of 5 S genes, occurring in several plant species, is fully compatible with their expression and functionality. This extraordinary 5 S gene dynamics is manifested at different levels, such as variation in intrachromosomal positions, unit structure, epigenetic modification and considerable divergence of regulatory motifs. PMID:22716941

  14. Integrated turbomachine oxygen plant

    DOEpatents

    Anand, Ashok Kumar; DePuy, Richard Anthony; Muthaiah, Veerappan

    2014-06-17

    An integrated turbomachine oxygen plant includes a turbomachine and an air separation unit. One or more compressor pathways flow compressed air from a compressor through one or more of a combustor and a turbine expander to cool the combustor and/or the turbine expander. An air separation unit is operably connected to the one or more compressor pathways and is configured to separate the compressed air into oxygen and oxygen-depleted air. A method of air separation in an integrated turbomachine oxygen plant includes compressing a flow of air in a compressor of a turbomachine. The compressed flow of air is flowed through one or more of a combustor and a turbine expander of the turbomachine to cool the combustor and/or the turbine expander. The compressed flow of air is directed to an air separation unit and is separated into oxygen and oxygen-depleted air.

  15. 40 CFR 60.1050 - Who must submit a materials separation plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Municipal Waste Combustion Units for Which Construction is Commenced After August 30, 1999 or for Which... separation plan for your municipal waste combustion unit if you commence construction of a new small municipal waste combustion unit after December 6, 2000. (b) If you commence construction of your municipal...

  16. 40 CFR 60.1050 - Who must submit a materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Municipal Waste Combustion Units for Which Construction is Commenced After August 30, 1999 or for Which... separation plan for your municipal waste combustion unit if you commence construction of a new small municipal waste combustion unit after December 6, 2000. (b) If you commence construction of your municipal...

  17. Continuous-flow electrophoretic separator for biologicals

    NASA Technical Reports Server (NTRS)

    Mccreight, L. R.; Griffin, R. N.; Locker, R. J.

    1976-01-01

    In the near absence of gravity, a continuous-flow type of electrophoretic separator can be operated with a much thicker separation chamber than is possible under 1 g conditions. This should permit either better resolution or shorter separation time per unit of sample. An apparatus to perform experiments on sounding rockets is under development and will be described. The electrophoresis cell is 5 mm thick by 5 cm wide with 10 cm long electrodes. It is supplied with buffer, sample, and coolant at about 4 C through the use of a passive refrigerant system. UV sample detection and provision for recovery and cold storage of up to 50 sample fractions are now being added to the basic unit. A wide range of operating conditions are electronically programmable into the unit, even up to a short time before flight, and a further range of some parameters can be achieved by exchanging power supplies and by changing gears in the motor drive units of the pump. The preliminary results of some separation studies on various biological products using a commercially available electrophoretic separator are also presented.

  18. Functional Status Score for the Intensive Care Unit (FSS-ICU): An International Clinimetric Analysis of Validity, Responsiveness, and Minimal Important Difference

    PubMed Central

    Huang, Minxuan; Chan, Kitty S.; Zanni, Jennifer M.; Parry, Selina M.; Neto, Saint-Clair G. B.; Neto, Jose A. A.; da Silva, Vinicius Z. M.; Kho, Michelle E.; Needham, Dale M.

    2017-01-01

    Objective To evaluate the internal consistency, validity, responsiveness, and minimal important difference of the Functional Status Score for the Intensive Care Unit (FSS-ICU), a physical function measure designed for the intensive care unit (ICU). Design Clinimetric analysis. Settings Five international data sets from the United States, Australia, and Brazil. Patients 819 ICU patients. Intervention None. Measurements and Main Results Clinimetric analyses were initially conducted separately for each data source and time point to examine generalizability of findings, with pooled analyses performed thereafter to increase power of analyses. The FSS-ICU demonstrated good to excellent internal consistency. There was good convergent and discriminant validity, with significant and positive correlations (r = 0.30 to 0.95) between FSS-ICU and other physical function measures, and generally weaker correlations with non-physical measures (|r| = 0.01 to 0.70). Known group validity was demonstrated by significantly higher FSS-ICU scores among patients without ICU-acquired weakness (Medical Research Council sumscore ≥48 versus <48) and with hospital discharge to home (versus healthcare facility). FSS-ICU at ICU discharge predicted post-ICU hospital length of stay and discharge location. Responsiveness was supported via increased FSS-ICU scores with improvements in muscle strength. Distribution-based methods indicated a minimal important difference of 2.0 to 5.0. Conclusions The FSS-ICU has good internal consistency and is a valid and responsive measure of physical function for ICU patients. The estimated minimal important difference can be used in sample size calculations and in interpreting studies comparing the physical function of groups of ICU patients. PMID:27488220

  19. Small scale homelike special care units and traditional special care units: effects on cognition in dementia; a longitudinal controlled intervention study.

    PubMed

    Kok, Jeroen S; van Heuvelen, Marieke J G; Berg, Ina J; Scherder, Erik J A

    2016-02-16

    Evidence shows that living in small scale homelike Special Care Units (SCU) has positive effects on behavioural and psychological symptoms of patients with dementia. Effects on cognitive functioning in relation to care facilities, however, are scarcely investigated. The purpose of this study is to gain more insight into the effects of living in small scale homelike Special Care Units, compared to regular SCU's, on the course of cognitive functioning in dementia. A group of 67 patients with dementia who moved from a regular SCU to a small scale homelike SCU and a group of 48 patients with dementia who stayed in a regular SCU participated in the study. Cognitive and behavioural functioning was assessed by means of a neuropsychological test battery and observation scales one month before (baseline), as well as 3 (post) and 6 months (follow-up) after relocation. Comparing the post and follow-up measurement with the baseline measurement, no significant differences on separate measures of cognitive functioning between both groups were found. Additional analyses, however, on 'domain clusters' revealed that global cognitive functioning of the small scale homelike SCU group showed significantly less cognitive decline three months after the transfer (p < 0.05). Effect sizes (95% CI) show a tendency for better aspects of cognition in favour of the homelike small scaled SCU group, i.e., visual memory, picture recognition, cognitive decline as observed by representatives and the clustered domains episodic memory and global cognitive functioning. While there is no significant longitudinal effect on the progression of cognitive decline comparing small scaled homelike SCU's with regular SCU's for patients with dementia, analyses on the domain clusters and effect sizes cautiously suggest differences in favour of the small scaled homelike SCU for different aspects of cognition.

  20. Underpressure in Mesozoic and Paleozoic rock units in the Midcontinent of the United States

    USGS Publications Warehouse

    Nelson, Philip H.; Gianoutsos, Nicholas J.; Drake, Ronald

    2015-01-01

    Potentiometric surfaces for Paleozoic strata, based on water well levels and selected drill-stem tests, reveal the control on hydraulic head exerted by outcrops in eastern Kansas and Oklahoma. From outcrop in the east, the westward climb of hydraulic head is much less than that of the land surface, with heads falling so far below land surface that the pressure:depth ratio in eastern Colorado is less than 5.7 kPa/m (0.25 psi/ft). Permian evaporites separate the Paleozoic hydrogeologic units from a Lower Cretaceous (Dakota Group) aquifer, and a highly saline brine plume pervading Paleozoic units in central Kansas and Oklahoma is attributed to dissolution of Permian halite. Underpressure also exists in the Lower Cretaceous hydrogeologic unit in the Denver Basin, which is hydrologically separate from the Paleozoic units. The data used to construct the seven potentiometric surfaces were also used to construct seven maps of pressure:depth ratio. These latter maps are a function of the differences among hydraulic head, land-surface elevation, and formation elevation. As a consequence, maps of pressure:depth ratio reflect the interplay of three topologies that evolved independently with time. As underpressure developed, gas migrated in response to the changing pressure regime, most notably filling the Hugoton gas field in southwestern Kansas. The timing of underpressure development was determined by the timing of outcrop exposure and tilting of the Great Plains. Explorationists in western Kansas and eastern Colorado should not be surprised if a reservoir is underpressured; rather, they should be surprised if it is not.

  1. Relationship Between Ktrans and K1 with Simultaneous Versus Separate MR/PET in Rabbits with VX2 Tumors.

    PubMed

    Lee, Kyung Hee; Kang, Seung Kwan; Goo, Jin Mo; Lee, Jae Sung; Cheon, Gi Jeong; Seo, Seongho; Hwang, Eui Jin

    2017-03-01

    To compare the relationship between K trans from DCE-MRI and K 1 from dynamic 13 N-NH 3 -PET, with simultaneous and separate MR/PET in the VX-2 rabbit carcinoma model. MR/PET was performed simultaneously and separately, 14 and 15 days after VX-2 tumor implantation at the paravertebral muscle. The K trans and K 1 values were estimated using an in-house software program. The relationships between K trans and K 1 were analyzed using Pearson's correlation coefficients and linear/non-linear regression function. Assuming a linear relationship, K trans and K 1 exhibited a moderate positive correlations with both simultaneous (r=0.54-0.57) and separate (r=0.53-0.69) imaging. However, while the K trans and K 1 from separate imaging were linearly correlated, those from simultaneous imaging exhibited a non-linear relationship. The amount of change in K 1 associated with a unit increase in K trans varied depending on K trans values. The relationship between K trans and K 1 may be mis-interpreted with separate MR and PET acquisition. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  2. Development of gas chromatography-flame ionization detection system with a single column and liquid nitrogen-free for measuring atmospheric C2-C12 hydrocarbons.

    PubMed

    Liu, Chengtang; Mu, Yujing; Zhang, Chenglong; Zhang, Zhibo; Zhang, Yuanyuan; Liu, Junfeng; Sheng, Jiujiang; Quan, Jiannong

    2016-01-04

    A liquid nitrogen-free GC-FID system equipped with a single column has been developed for measuring atmospheric C2-C12 hydrocarbons. The system is consisted of a cooling unit, a sampling unit and a separation unit. The cooling unit is used to meet the temperature needs of the sampling unit and the separation unit. The sampling unit includes a dehydration tube and an enrichment tube. No breakthrough of the hydrocarbons was detected when the temperature of the enrichment tube was kept at -90 °C and sampling volume was 400 mL. The separation unit is a small round oven attached on the cooling column. A single capillary column (OV-1, 30 m × 0.32 mm I.D.) was used to separate the hydrocarbons. An optimal program temperature (-60 ∼ 170 °C) of the oven was achieved to efficiently separate C2-C12 hydrocarbons. There were good linear correlations (R(2)=0.993-0.999) between the signals of the hydrocarbons and the enrichment amount of hydrocarbons, and the relative standard deviation (RSD) was less than 5%, and the method detection limits (MDLs) for the hydrocarbons were in the range of 0.02-0.10 ppbv for sampling volume of 400 mL. Field measurements were also conducted and more than 50 hydrocarbons from C2 to C12 were detected in Beijing city. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Oxy-fired boiler unit and method of operating the same

    DOEpatents

    Lou, Xinsheng; Zhang, Jundong; Joshi, Abhinaya; McCombe, James A.; Levasseur, Armand A.

    2016-12-06

    An oxy-combustion boiler unit is disclosed which includes a furnace for combusting fuel and for emitting flue gas resulting from combustion. The furnace has first, second and third combustion zones, and an air separation unit for separating oxygen gas from air and providing a first portion of the separated oxygen to a first oxidant flow, a second portion to a second oxidant flow, and a third portion of the separated oxygen gas to the first, second, and third zones of the furnace. A controller can cause the separated oxygen gas to be distributed so that the first and second oxygen flows have a desired oxygen content, and so that the first, second, and third zones of the furnace receive a desired amount of oxygen based on a combustion zone stoichiometry control.

  4. Defense Science Board 2006 Summer Study of Information Management for Net-Centric Operations. Volume 2. Operations Panel Report

    DTIC Science & Technology

    2007-04-01

    and/or time de-confliction to insure safe separation of component forces. For example, in the Vietnam era, Air Force units were employed in the Hanoi...systems and people to exploit it. For example, Accenture (Accenture.com), a $15 billion global management consulting and technology services company ...information managers (called knowledge managers) to functional specialties, such as oil, gas, insurance , and pharmaceuticals. Information managers collect

  5. Assembly of Photosynthetic Antenna Protein Complexes from Algae for Development of Nano-biodevice and Its Fuelization

    DTIC Science & Technology

    2013-05-20

    More recently the structures of the LH2 complexes has revealed the nonameric and octameric arrangement of repeating units consisting of two...Compartimentalization of light -harvesting and charge separation. The antenna complexes( LH2 ,LH1-RC) efficiently realize various photosynthetic functions...using cofactors (BChl a and carotenoid) assembled into the apoproteins (LH1 and LH2 ). The light-harvesting mechanisms in these light-harvesting

  6. Assembly of Photosynthetic Antenna Protein / Pigments Complexes from Algae and Plants for Development of Nanobiodevices

    DTIC Science & Technology

    2012-07-10

    recently the structures of the LH2 complexes has revealed the nonameric and octameric arrangement of repeating units consisting of two apoproteins and...Compartimentalization of light -harvesting and charge separation. The antenna complexes( LH2 ,LH1-RC) efficiently realize various photosynthetic functions using...cofactors (BChl a and carotenoid) assembled into the apoproteins (LH1 and LH2 ). The light-harvesting mechanisms in these light-harvesting complexes have

  7. Japanese Nationalism

    DTIC Science & Technology

    1989-06-01

    United States. The chief function of this principle is to cut--it separates all things. It classifies everything into black and white, good and bad . The...content included articles on masturbation , petting, and 99 intercourse. One of Japan’s all time best selling books in recent years, Totto-chan, is a...to the th: every Japanese will be judged by whether he celebrates this or not. That is how people will be determined to be good Japanese or bad 112

  8. Annular feed air breathing fuel cell stack

    DOEpatents

    Wilson, Mahlon S.; Neutzler, Jay K.

    1997-01-01

    A stack of polymer electrolyte fuel cells is formed from a plurality of unit cells where each unit cell includes fuel cell components defining a periphery and distributed along a common axis, where the fuel cell components include a polymer electrolyte membrane, an anode and a cathode contacting opposite sides of the membrane, and fuel and oxygen flow fields contacting the anode and the cathode, respectively, wherein the components define an annular region therethrough along the axis. A fuel distribution manifold within the annular region is connected to deliver fuel to the fuel flow field in each of the unit cells. The fuel distribution manifold is formed from a hydrophilic-like material to redistribute water produced by fuel and oxygen reacting at the cathode. In a particular embodiment, a single bolt through the annular region clamps the unit cells together. In another embodiment, separator plates between individual unit cells have an extended radial dimension to function as cooling fins for maintaining the operating temperature of the fuel cell stack.

  9. Separation of mouse testis cells on a Celsep (TM) apparatus and their usefulness as a source of high molecular weight DNA or RNA

    NASA Technical Reports Server (NTRS)

    Wolgemuth, D. J.; Gizang-Ginsberg, E.; Engelmyer, E.; Gavin, B. J.; Ponzetto, C.

    1985-01-01

    The use of a self-contained unit-gravity cell separation apparatus for separation of populations of mouse testicular cells is described. The apparatus, a Celsep (TM), maximizes the unit area over which sedimentation occurs, reduces the amount of separation medium employed, and is quite reproducible. Cells thus isolated have been good sources for isolation of DNA, and notably, high molecular weight RNA.

  10. Two separable functional domains of simian virus 40 large T antigen: carboxyl-terminal region of simian virus 40 large T antigen is required for efficient capsid protein synthesis.

    PubMed Central

    Tornow, J; Polvino-Bodnar, M; Santangelo, G; Cole, C N

    1985-01-01

    The carboxyl-terminal portion of simian virus 40 large T antigen is essential for productive infection of CV-1 and CV-1p green monkey kidney cells. Mutant dlA2459, lacking 14 base pairs at 0.193 map units, was positive for viral DNA replication, but unable to form plaques in CV-1p cells (J. Tornow and C.N. Cole, J. Virol. 47:487-494, 1983). In this report, the defect of dlA2459 is further defined. Simian virus 40 late mRNAs were transcribed, polyadenylated, spliced, and transported in dlA2459-infected cells, but the level of capsid proteins produced in infected CV-1 green monkey kidney cells was extremely low. dlA2459 large T antigen lacks those residues known to be required for adenovirus helper function, and the block to productive infection by dlA2459 occurs at the same stage of infection as the block to productive adenovirus infection of CV-1 cells. These results suggest that the adenovirus helper function is required for productive infection by simian virus 40. Mutant dlA2459 was able to grow on the Vero and BSC-1 lines of African green monkey kidney cells. Additional mutants affecting the carboxyl-terminal portion of large T were prepared. Mutant inv2408 contains an inversion of the DNA between the BamHI and BclI sites (0.144 to 0.189 map units). This inversion causes transposition of the carboxyl-terminal 26 amino acids of large T antigen and the carboxyl-terminal 18 amino acids of VP1. This mutant was viable, even though the essential information absent from dlA2459 large T antigen has been transferred to the carboxyl terminus of VP1 of inv2408. The VP1 polypeptide carrying this carboxyl-terminal portion of large T could overcome the defect of dlA2459. This indicates that the carboxyl terminus of large T antigen is a separate and separable functional domain. Images PMID:2982029

  11. Thermosyphon coil arrangement for heat pump outdoor unit

    DOEpatents

    Draper, R.

    1984-05-22

    For a heat pump, the outdoor unit is provided with a coil and a refrigerant flow arrangement there for which is such that in the heating mode of operation of the heat pump they operate in a thermosyphon fashion. The coil has a feed portion and an exit portion leading to a separator drum from which liquid refrigerant is returned through downcomer line for recirculation to the feed portion. The coil is tilted upwardly from entry to exit by the angle alpha to enhance the clearance of the two phases of refrigerant from each other in the heating mode of operation. There is no thermosyphon function in the cooling mode of operation. 9 figs.

  12. Thermosyphon coil arrangement for heat pump outdoor unit

    DOEpatents

    Draper, Robert

    1984-01-01

    For a heat pump, the outdoor unit is provided with a coil and a refrigerant flow arrangement therefor which is such that in the heating mode of operation of the heat pump they operate in a thermosyphon fashion. The coil 32 has a feed portion 30 and an exit portion 34 leading to a separator drum 36 from which liquid refrigerant is returned through downcomer line 42 for recirculation to the feed portion. The coil is tilted upwardly from entry to exit by the angle alpha to enhance the clearance of the two phases of refrigerant from each other in the heating mode of operation. There is no thermosyphon function in the cooling mode of operation.

  13. United States Air Force Summer Faculty Research Program (1987). Program Technical Report. Volume 2.

    DTIC Science & Technology

    1987-12-01

    the area of statistical inference, distribution theory and stochastic * •processes. I have taught courses in random processes and sample % j .functions...controlled phase separation of isotropic, binary mixtures, the theory of spinodal decomposition has been developed by Cahn and Hilliard.5 ,6 This theory is...peak and its initial rate of growth at a given temperature are predicted by the spinodal theory . The angle of maximum intensity is then determined by

  14. Vacuum distillation: vapor filtered-catalytic oxidation water reclamation system utilizing radioisotopes

    NASA Technical Reports Server (NTRS)

    Honegger, R. J.; Remus, G. A.; Kurg, E. K.

    1971-01-01

    The development of a functional model water reclamation system is discussed. The system produces potable water by distillation from the urine and respiration-perspiration condensate at the normal rate generated by four men. Basic processes employed are vacuum distillation, vapor filtration, vapor phase catalytic oxidation, and condensation. The system is designed to use four 75-watt isotope heaters for distillation thermal input, and one 45-watt isotope for the catalytic oxidation unit. The system is capable of collecting and storing urine, and provides for stabilizing the urine by chemical pretreatment. The functional model system is designed for operation in a weightless condition with liquid-vapor phase separators for the evaporator still, and centrifugal separators for urine collection and vapor condensation. The system provides for storing and dispensing reclaimed potable water. The system operates in a batch mode for 40 days, with urine residues accumulating in the evaporator. The evaporator still and residue are removed to storage and replaced with a fresh still for the next 40-day period.

  15. Evaluation of phase separator number in hydrodesulfurization (HDS) unit

    NASA Astrophysics Data System (ADS)

    Jayanti, A. D.; Indarto, A.

    2016-11-01

    The removal process of acid gases such as H2S in natural gas processing industry is required in order to meet sales gas specification. Hydrodesulfurization (HDS)is one of the processes in the refinery that is dedicated to reduce sulphur.InHDS unit, phase separator plays important role to remove H2S from hydrocarbons, operated at a certain pressure and temperature. Optimization of the number of separator performed on the system is then evaluated to understand the performance and economics. From the evaluation, it shows that all systems were able to meet the specifications of H2S in the desired product. However, one separator system resulted the highest capital and operational costs. The process of H2S removal with two separator systems showed the best performance in terms of both energy efficiency with the lowest capital and operating cost. The two separator system is then recommended as a reference in the HDS unit to process the removal of H2S from natural gas.

  16. Methods and apparatus for catalytic hydrothermal gasification of biomass

    DOEpatents

    Elliott, Douglas C.; Butner, Robert Scott; Neuenschwander, Gary G.; Zacher, Alan H.; Hart, Todd R.

    2012-08-14

    Continuous processing of wet biomass feedstock by catalytic hydrothermal gasification must address catalyst fouling and poisoning. One solution can involve heating the wet biomass with a heating unit to a temperature sufficient for organic constituents in the feedstock to decompose, for precipitates of inorganic wastes to form, for preheating the wet feedstock in preparation for subsequent separation of sulfur contaminants, or combinations thereof. Treatment further includes separating the precipitates out of the wet feedstock, removing sulfur contaminants, or both using a solids separation unit and a sulfur separation unit, respectively. Having removed much of the inorganic wastes and the sulfur that can cause poisoning and fouling, the wet biomass feedstock can be exposed to the heterogeneous catalyst for gasification.

  17. Alkaline battery containing a separator of a cross-linked copolymer of vinyl alcohol and unsaturated carboxylic acid

    NASA Technical Reports Server (NTRS)

    Hsu, L. C.; Philipp, W. H.; Sheibley, D. W.; Gonzalez-Sanabria, O. D. (Inventor)

    1985-01-01

    A battery separator for an alkaline battery is described. The separator comprises a cross linked copolymer of vinyl alcohol units and unsaturated carboxylic acid units. The cross linked copolymer is insoluble in water, has excellent zincate diffusion and oxygen gas barrier properties and a low electrical resistivity. Cross linking with a polyaldehyde cross linking agent is preferred.

  18. Study of limitations and attributes of microprocessor testing techniques

    NASA Technical Reports Server (NTRS)

    Mccaskill, R.; Sohl, W. E.

    1977-01-01

    All microprocessor units have a similar architecture from which a basic test philosophy can be adopted and used to develop an approach to test each module separately in order to verify the functionality of each module within the device using the input/output pins of the device and its instruction set; test for destructive interaction between functional modules; and verify all timing, status information, and interrupt operations of the device. Block and test flow diagrams are given for the 8080, 8008, 2901, 6800, and 1802 microprocessors. Manufacturers are listed and problems encountered in testing the modules are discussed. Test equipment and methods are described.

  19. Development of micropump-actuated negative pressure pinched injection for parallel electrophoresis on array microfluidic chip.

    PubMed

    Li, Bowei; Jiang, Lei; Xie, Hua; Gao, Yan; Qin, Jianhua; Lin, Bingcheng

    2009-09-01

    A micropump-actuated negative pressure pinched injection method is developed for parallel electrophoresis on a multi-channel LIF detection system. The system has a home-made device that could individually control 16-port solenoid valves and a high-voltage power supply. The laser beam is excitated and distributes to the array separation channels for detection. The hybrid Glass-PDMS microfluidic chip comprises two common reservoirs, four separation channels coupled to their respective pneumatic micropumps and two reference channels. Due to use of pressure as a driving force, the proposed method has no sample bias effect for separation. There is only one high-voltage supply needed for separation without relying on the number of channels, which is significant for high-throughput analysis, and the time for sample loading is shortened to 1 s. In addition, the integrated micropumps can provide the versatile interface for coupling with other function units to satisfy the complicated demands. The performance is verified by separation of DNA marker and Hepatitis B virus DNA samples. And this method is also expected to show the potential throughput for the DNA analysis in the field of disease diagnosis.

  20. Optimization of steam generators of NPP with WWER in operation with variable load

    NASA Astrophysics Data System (ADS)

    Parchevskii, V. M.; Shchederkina, T. E.; Gur'yanova, V. V.

    2017-11-01

    The report addresses the issue of the optimal water level in the horizontal steam generators of NPP with WWER. On the one hand, the level needs to be kept at the lower limit of the allowable range, as gravity separation, steam will have the least humidity and the turbine will operate with higher efficiency. On the other hand, the higher the level, the greater the supply of water in the steam generator, and therefore the higher the security level of the unit, because when accidents involving loss of cooling of the reactor core, the water in the steam generators, can be used for cooling. To quantitatively compare the damage from higher level to the benefit of improving the safety was assessed of the cost of one cubic meter of water in the steam generators, the formulated objective function of optimal levels control. This was used two-dimensional separation characteristics of steam generators. It is demonstrated that the security significantly shifts the optimal values of the levels toward the higher values, and this bias is greater the lower the load unit.

  1. Upgrading the SPP-500-1 moisture separators-steam reheaters used in the Leningrad NPP turbine units

    NASA Astrophysics Data System (ADS)

    Legkostupova, V. V.; Sudakov, A. V.

    2015-03-01

    The specific features of existing designs of moisture separators-steam reheaters (MSRs) and experience gained with using them at nuclear power plants are considered. Main factors causing damage to and failures of MSRs are described: nonuniform distribution of wet steam flow among the separation modules, breakthrough of moisture through the separator (and sometimes also through the steam reheater), which may lead to the occurrence of additional thermal stresses and, hence, to thermal-fatigue damage to or stress corrosion cracking of metal. MSR failure results in a less efficient operation of the turbine unit as a whole and have an adverse effect on the reliability of the low-pressure cylinder's last-stage blades. By the time the design service life of the SPP-500-1 MSRs had been exhausted in power units equipped with RBMK-1000 reactors, the number of damages inflicted to both the separation part and to the pipework and heating surface tubes was so large, that a considerable drop of MSR effectiveness and turbine unit efficiency as a whole occurred. The design of the upgraded separation part used in the SPP-500-1 MSR at the Leningrad NPP is described and its effectiveness is shown, which was confirmed by tests. First, efforts taken to achieve more uniform distribution of moisture content over the perimeter and height of steam space downstream of the separation modules and to bring it to values close to the design ones were met with success. Second, no noticeable effect of the individual specific features of separation modules on the moisture content was revealed. Recommendations on elaborating advanced designs of moisture separators-steam reheaters are given: an MSR arrangement in which the separator is placed under or on the side from the steam reheater; axial admission of wet steam for ensuring its uniform distribution among the separation modules; inlet chambers with an extended preliminary separation system and devices for uniformly distributing steam flows in the separator; separated layout of the of the separator and steam reheater; and use of transversely finned tube bundles for organizing cross flow of steam over the tubes.

  2. Compact cyclone filter train for radiological and hazardous environments

    DOEpatents

    Bench, Thomas R.

    1998-01-01

    A compact cyclone filter train for the removal of hazardous and radiologi particles from a gaseous fluid medium which permits a small cyclone separator to be used in a very small space envelope due to the arrangement of the filter housing adjacent to the separator with the cyclone separator and the filters mounted on a plate. The entire unit will have a hoist connection at the center of gravity so that the entire unit including the separator, the filters, and the base can be lifted and repositioned as desired.

  3. 40 CFR 63.961 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... access lid or hatch), or automatically operated (e.g., a spring-loaded pressure relief valve). Hard... includes hard-piping, all drains and junction boxes, together with their associated sewer lines and other... management units include containers, air flotation units, oil-water separators or organic-water separators...

  4. 40 CFR 63.961 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... access lid or hatch), or automatically operated (e.g., a spring-loaded pressure relief valve). Hard... includes hard-piping, all drains and junction boxes, together with their associated sewer lines and other... management units include containers, air flotation units, oil-water separators or organic-water separators...

  5. 40 CFR 63.961 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... access lid or hatch), or automatically operated (e.g., a spring-loaded pressure relief valve). Hard... includes hard-piping, all drains and junction boxes, together with their associated sewer lines and other... management units include containers, air flotation units, oil-water separators or organic-water separators...

  6. Developing rapid methods for analyzing upland riparian functions and values.

    PubMed

    Hruby, Thomas

    2009-06-01

    Regulators protecting riparian areas need to understand the integrity, health, beneficial uses, functions, and values of this resource. Up to now most methods providing information about riparian areas are based on analyzing condition or integrity. These methods, however, provide little information about functions and values. Different methods are needed that specifically address this aspect of riparian areas. In addition to information on functions and values, regulators have very specific needs that include: an analysis at the site scale, low cost, usability, and inclusion of policy interpretations. To meet these needs a rapid method has been developed that uses a multi-criteria decision matrix to categorize riparian areas in Washington State, USA. Indicators are used to identify the potential of the site to provide a function, the potential of the landscape to support the function, and the value the function provides to society. To meet legal needs fixed boundaries for assessment units are established based on geomorphology, the distance from "Ordinary High Water Mark" and different categories of land uses. Assessment units are first classified based on ecoregions, geomorphic characteristics, and land uses. This simplifies the data that need to be collected at a site, but it requires developing and calibrating a separate model for each "class." The approach to developing methods is adaptable to other locations as its basic structure is not dependent on local conditions.

  7. 40 CFR 63.1423 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (subpart F) Incinerator (subpart G) Major source (subpart A) Malfunction (subpart A) Oil-water separator or organic-water separator (subpart G) Open-ended valve or line (subpart H) Operating permit (subpart F... process unit consists of more than one unit operation. This collection of equipment includes purification...

  8. 40 CFR 63.1423 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (subpart F) Incinerator (subpart G) Major source (subpart A) Malfunction (subpart A) Oil-water separator or organic-water separator (subpart G) Open-ended valve or line (subpart H) Operating permit (subpart F... process unit consists of more than one unit operation. This collection of equipment includes purification...

  9. A portable system for processing donated whole blood into high quality components without centrifugation.

    PubMed

    Gifford, Sean C; Strachan, Briony C; Xia, Hui; Vörös, Eszter; Torabian, Kian; Tomasino, Taylor A; Griffin, Gary D; Lichtiger, Benjamin; Aung, Fleur M; Shevkoplyas, Sergey S

    2018-01-01

    The use of centrifugation-based approaches for processing donated blood into components is routine in the industrialized world, as disparate storage conditions require the rapid separation of 'whole blood' into distinct red blood cell (RBC), platelet, and plasma products. However, the logistical complications and potential cellular damage associated with centrifugation/apheresis manufacturing of blood products are well documented. The objective of this study was to evaluate a proof-of-concept system for whole blood processing, which does not employ electromechanical parts, is easily portable, and can be operated immediately after donation with minimal human labor. In a split-unit study (n = 6), full (~500mL) units of freshly-donated whole blood were divided, with one half processed by conventional centrifugation techniques and the other with the new blood separation system. Each of these processes took 2-3 hours to complete and were performed in parallel. Blood products generated by the two approaches were compared using an extensive panel of cellular and plasma quality metrics. Comparison of nearly all RBC parameters showed no significant differences between the two approaches, although the portable system generated RBC units with a slight but statistically significant improvement in 2,3-diphosphoglyceric acid concentration (p < 0.05). More notably, several markers of platelet damage were significantly and meaningfully higher in products generated with conventional centrifugation: the increase in platelet activation (assessed via P-selectin expression in platelets before and after blood processing) was nearly 4-fold higher for platelet units produced via centrifugation, and the release of pro-inflammatory mediators (soluble CD40-ligand, thromboxane B2) was significantly higher for centrifuged platelets as well (p < 0.01). This study demonstrated that a simple, passive system for separating donated blood into components may be a viable alternative to centrifugation-particularly for applications in remote or resource-limited settings, or for patients requiring highly functional platelet product.

  10. Implementation of acoustic demultiplexing with membrane-type metasurface in low frequency range

    NASA Astrophysics Data System (ADS)

    Chen, Xing; Liu, Peng; Hou, Zewei; Pei, Yongmao

    2017-04-01

    Wavelength division multiplexing technology, adopted to increase the information density, plays a significant role in optical communication. However, in acoustics, a similar function can be hardly implemented due to the weak dispersion in natural acoustic materials. Here, an acoustic demultiplexer, based on the concept of metasurfaces, is proposed for splitting acoustic waves and propagating along different trajectories in a low frequency range. An acoustic metasurface, containing multiple resonant units, is designed with various phase profiles for different frequencies. Originating from the highly dispersive properties, the resonant units are independent and merely work in the vicinity of their resonant frequencies. Therefore, by combing multiple resonant units appropriately, the phenomena of anomalous reflection, acoustic focusing, and acoustic wave bending can occur in different frequencies. The proposed acoustic demultiplexer has advantages on the subwavelength scale and the versatility in wave control, providing a strategy for separating acoustic waves with different Fourier components.

  11. Thermodynamic analysis of the advanced zero emission power plant

    NASA Astrophysics Data System (ADS)

    Kotowicz, Janusz; Job, Marcin

    2016-03-01

    The paper presents the structure and parameters of advanced zero emission power plant (AZEP). This concept is based on the replacement of the combustion chamber in a gas turbine by the membrane reactor. The reactor has three basic functions: (i) oxygen separation from the air through the membrane, (ii) combustion of the fuel, and (iii) heat transfer to heat the oxygen-depleted air. In the discussed unit hot depleted air is expanded in a turbine and further feeds a bottoming steam cycle (BSC) through the main heat recovery steam generator (HRSG). Flue gas leaving the membrane reactor feeds the second HRSG. The flue gas consist mainly of CO2 and water vapor, thus, CO2 separation involves only the flue gas drying. Results of the thermodynamic analysis of described power plant are presented.

  12. A new analysis of charge transfer and polarization for ligand-metal bonding - Model studies of Al4CO and Al4NH3

    NASA Technical Reports Server (NTRS)

    Bagus, P. S.; Hermann, K.; Bauschlicher, C. W., Jr.

    1984-01-01

    The nature of the bonding of CO and NH3 ligands to Al is analyzed, and the intra-unit charge polarization and inter-unit donation for the interaction of ligands with metals are studied. The consequences of metal-to-ligand and ligand-to-metal charge transfer are separately considered by performing a constrained space orbital variation (CSOV) with the electrons of the metal member of the complex in the field of frozen ligand. The electrons of the metal atoms are then frozen in the relaxed distribution given by the CSOV SCF wave function and the ligand electrons are allowed to relax. Quantitative measures of the importance of inter-unit charge transfers and intra-unit polarization are obtained using results of SCF studies of Al4CO and Al4NH3 clusters chosen to simulate the adsorption of the ligands at an on-top side of the Al(111) surface. The electrostatic attraction of the effective dipole moments of the metal and ligand units makes an important contribution to the bond.

  13. 45 CFR 302.12 - Single and separate organizational unit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Single and separate organizational unit. 302.12 Section 302.12 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND...

  14. Visualization of early events in acetic acid denaturation of HIV-1 protease: a molecular dynamics study.

    PubMed

    Borkar, Aditi Narendra; Rout, Manoj Kumar; Hosur, Ramakrishna V

    2011-01-01

    Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent. The PR dimer and monomer were simulated separately in 9 M acetic acid (9 M AcOH) solution and water to study the denaturation process of PR in acetic acid environment. Direct visualization of the denaturation dynamics that is readily available from such simulations has been presented. Our simulations in 9 M AcOH reveal that the PR denaturation begins by separation of dimer into intact monomers and it is only after this separation that the monomer units start denaturing. The denaturation of the monomers is flagged off by the loss of crucial interactions between the α-helix at C-terminal and surrounding β-strands. This causes the structure to transit from the equilibrium dynamics to random non-equilibrating dynamics. Residence time calculations indicate that denaturation occurs via direct interaction of the acetic acid molecules with certain regions of the protein in 9 M AcOH. All these observations have helped to decipher a picture of the early events in acetic acid denaturation of PR and have illustrated that the α-helix and the β-sheet at the C-terminus of a native and functional PR dimer should maintain both the stability and the function of the enzyme and thus present newer targets for blocking PR function.

  15. Conceptual design of distillation-based hybrid separation processes.

    PubMed

    Skiborowski, Mirko; Harwardt, Andreas; Marquardt, Wolfgang

    2013-01-01

    Hybrid separation processes combine different separation principles and constitute a promising design option for the separation of complex mixtures. Particularly, the integration of distillation with other unit operations can significantly improve the separation of close-boiling or azeotropic mixtures. Although the design of single-unit operations is well understood and supported by computational methods, the optimal design of flowsheets of hybrid separation processes is still a challenging task. The large number of operational and design degrees of freedom requires a systematic and optimization-based design approach. To this end, a structured approach, the so-called process synthesis framework, is proposed. This article reviews available computational methods for the conceptual design of distillation-based hybrid processes for the separation of liquid mixtures. Open problems are identified that must be addressed to finally establish a structured process synthesis framework for such processes.

  16. Modern bioanalysis of proteins by electrophoretic techniques.

    PubMed

    Krizkova, Sona; Ryvolova, Marketa; Masarik, Michal; Zitka, Ondrej; Adam, Vojtech; Hubalek, Jaromir; Eckschlager, Tomas; Kizek, Rene

    2014-01-01

    In 1957, protein rich in cysteine able to bind cadmium was isolated from horse kidney and named as metallothionein according to its structural properties. Further, this protein and metallothionein-like proteins have been found in tissues of other animal species, yeasts, fungi and plants. MT is as a potential cancer marker in the focus of interest, and its properties, functions, and behavior under various conditions are intensively studied. Our protocol describes separation of two major mammalian isoforms of MT (MT-1 and MT-2) using capillary electrophoresis (CE) coupled with UV detector. This protocol enables separation of MT isoforms and studying of their basic behavior as well as their quantification with detection limit in units of ng per μL. Sodium borate buffer (20 mM, pH 9.5) was optimized as a background electrolyte, and the separation was carried out in fused silica capillary with internal diameter of 75 μm and electric field intensity of 350 V/cm. Optimal detection wavelength was 254 nm.

  17. Pattern formation in mass conserving reaction-diffusion systems

    NASA Astrophysics Data System (ADS)

    Brauns, Fridtjof; Halatek, Jacob; Frey, Erwin

    We present a rigorous theoretical framework able to generalize and unify pattern formation for quantitative mass conserving reaction-diffusion models. Mass redistribution controls chemical equilibria locally. Separation of diffusive mass redistribution on the level of conserved species provides a general mathematical procedure to decompose complex reaction-diffusion systems into effectively independent functional units, and to reveal the general underlying bifurcation scenarios. We apply this framework to Min protein pattern formation and identify the mechanistic roles of both involved protein species. MinD generates polarity through phase separation, whereas MinE takes the role of a control variable regulating the existence of MinD phases. Hence, polarization and not oscillations is the generic core dynamics of Min proteins in vivo. This establishes an intrinsic mechanistic link between the Min system and a broad class of intracellular pattern forming systems based on bistability and phase separation (wave-pinning). Oscillations are facilitated by MinE redistribution and can be understood mechanistically as relaxation oscillations of the polarization direction.

  18. Preparation of red blood cell concentrates and plasma units from whole blood held overnight using a hollow-fibre separation system.

    PubMed

    Johnson, L; Kwok, M; Marks, D C

    2015-02-01

    The ErySep system represents an alternative to centrifuge-based whole blood (WB) separation, using gravity and filtration through hollow-fibres (0·2 µm pore size) to produce red blood cell (RBC) and plasma components. The aim of this study was to characterise the quality of ErySep RBC and plasma units compared with standard products from WB held overnight. Two ABO-compatible WB units (n = 24) were pooled and split to produce matched products. One of the WB units was separated into components using the ErySep system (ErySep; n = 12), whereas the other units were separated by centrifugation (control; n = 12). RBC units were stored at 2-6 °C and assessed for in vitro quality over 42 days of storage. Plasma was frozen at -30 °C and tested upon thawing. Processing WB with the ErySep system took longer than controls. The ErySep RBC units were of an appropriate volume (307 ± 17 mL) and contained sufficient Hb (50 ± 2 g unit(-1) ). ErySep RBC components contained more microparticles relative to controls at expiry. The plasma volume, total protein, coagulation factor activity (fibrinogen, FV, FVIII) and number of microparticles was lower in the ErySep units compared with controls. Following overnight hold of WB, the ErySep system was capable of producing RBC components that met specifications. However, the ErySep plasma components did not meet quality specifications. © 2015 British Blood Transfusion Society.

  19. Grouping in decomposition method for multi-item capacitated lot-sizing problem with immediate lost sales and joint and item-dependent setup cost

    NASA Astrophysics Data System (ADS)

    Narenji, M.; Fatemi Ghomi, S. M. T.; Nooraie, S. V. R.

    2011-03-01

    This article examines a dynamic and discrete multi-item capacitated lot-sizing problem in a completely deterministic production or procurement environment with limited production/procurement capacity where lost sales (the loss of customer demand) are permitted. There is no inventory space capacity and the production activity incurs a fixed charge linear cost function. Similarly, the inventory holding cost and the cost of lost demand are both associated with a linear no-fixed charge function. For the sake of simplicity, a unit of each item is assumed to consume one unit of production/procurement capacity. We analyse a different version of setup costs incurred by a production or procurement activity in a given period of the planning horizon. In this version, called the joint and item-dependent setup cost, an additional item-dependent setup cost is incurred separately for each produced or ordered item on top of the joint setup cost.

  20. Modality distribution of sensory neurons in the feline caudate nucleus and the substantia nigra.

    PubMed

    Márkus, Zita; Eördegh, Gabriella; Paróczy, Zsuzsanna; Benedek, G; Nagy, A

    2008-09-01

    Despite extensive analysis of the motor functions of the basal ganglia and the fact that multisensory information processing appears critical for the execution of their behavioral action, little is known concerning the sensory functions of the caudate nucleus (CN) and the substantia nigra (SN). In the present study, we set out to describe the sensory modality distribution and to determine the proportions of multisensory units within the CN and the SN. The separate single sensory modality tests demonstrated that a majority of the neurons responded to only one modality, so that they seemed to be unimodal. In contrast with these findings, a large proportion of these neurons exhibited significant multisensory cross-modal interactions. Thus, these neurons should also be classified as multisensory. Our results suggest that a surprisingly high proportion of sensory neurons in the basal ganglia are multisensory, and demonstrate that an analysis without a consideration of multisensory cross-modal interactions may strongly underrepresent the number of multisensory units. We conclude that a majority of the sensory neurons in the CN and SN process multisensory information and only a minority of these units are clearly unimodal.

  1. Compact cyclone filter train for radiological and hazardous environments

    DOEpatents

    Bench, T.R.

    1998-04-28

    A compact cyclone filter train is disclosed for the removal of hazardous and radiological particles from a gaseous fluid medium. This filter train permits a small cyclone separator to be used in a very small space envelope due to the arrangement of the filter housing adjacent to the separator with the cyclone separator and the filters mounted on a plate. The entire unit will have a hoist connection at the center of gravity so that the entire unit including the separator, the filters, and the base can be lifted and repositioned as desired. 3 figs.

  2. Design for multipurpose use: an application of DfE concept in a developing economy

    NASA Astrophysics Data System (ADS)

    Dunmade, Israel

    2004-12-01

    Design for Environment (DfE) has been defined as the systematic integration of environmental considerations into product and process design. And it has been discovered that material and space can be saved when several functions are integrated into a single product by taking advantage of common components. In this design and development project, a multipurpose thresher was designed based on an integrated concept of design for modularity, disassembly, demanufacturing and remanufacturing. The machine can be used to thresh various types of farm produce such as rice, sorghum, cowpea and rye by changing the concave and the cylinder (threshing drum). The configuration of the machine enables access to most of the component parts without changing the tools needed for disassembly because the same type of fasteners was used. Furthermore, the functional units (the shelling unit, the separation unit and the grading unit) were assembled into modules such that only the faulty part needs to be replaced if necessary. The design was so simplified that the operator can make the changes for different uses without any difficulty. The machine has been successfully tested with a number of these products and it is scheduled for tests with other produce like corn and peanuts. The modularity of the functional unit will facilitate multi-lifecycle use of machine and/or its component parts. The uniformity of the liaisons and simplification of the configuration will reduce both the disassembly times and maintenance cost. By this integration, the material requirements for four different machines are conserved, environmental emissions that would be associated with the manufacture, transportation and disposal of four machines are eliminated while the capital requirements by farmers for machinery are reduced to about a quarter. Consequently the total lifecycle cost is kept minimum while the eco-efficiency is maximized.

  3. 45 CFR 1321.55 - Organization and staffing of the area agency.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS... purpose is to administer programs for older persons; or (2) A separate organizational unit within a multi... agency on aging designates, as an area agency on aging, a separate organizational unit of a multipurpose...

  4. 45 CFR 1321.55 - Organization and staffing of the area agency.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS... purpose is to administer programs for older persons; or (2) A separate organizational unit within a multi... agency on aging designates, as an area agency on aging, a separate organizational unit of a multipurpose...

  5. 40 CFR 63.1567 - What are my requirements for inorganic HAP emissions from catalytic reforming units?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... different reactors in the catalytic reforming unit are regenerated in separate regeneration systems, then these emission limitations apply to each separate regeneration system. These emission limitations apply... catalyst rejuvenation operations during coke burn-off and catalyst regeneration. You can choose from the...

  6. 40 CFR 63.1567 - What are my requirements for inorganic HAP emissions from catalytic reforming units?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... different reactors in the catalytic reforming unit are regenerated in separate regeneration systems, then these emission limitations apply to each separate regeneration system. These emission limitations apply... catalyst rejuvenation operations during coke burn-off and catalyst regeneration. You can choose from the...

  7. 40 CFR 63.1567 - What are my requirements for inorganic HAP emissions from catalytic reforming units?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... different reactors in the catalytic reforming unit are regenerated in separate regeneration systems, then these emission limitations apply to each separate regeneration system. These emission limitations apply... catalyst rejuvenation operations during coke burn-off and catalyst regeneration. You can choose from the...

  8. Impact of the reduced vertical separation minimum on the domestic United States

    DOT National Transportation Integrated Search

    2009-01-31

    Aviation regulatory bodies have enacted the reduced vertical separation minimum standard over most of the globe. The reduced vertical separation minimum is a technique that reduces the minimum vertical separation distance between aircraft from 2000 t...

  9. Characterization of the Adult Head Transcriptome and Identification of Migration and Olfaction Genes in the Oriental Armyworm Mythimna separate.

    PubMed

    Bian, Hai-Xu; Ma, Hong-Fang; Zheng, Xi-Xi; Peng, Ming-Hui; Li, Yu-Ping; Su, Jun-Fang; Wang, Huan; Li, Qun; Xia, Run-Xi; Liu, Yan-Qun; Jiang, Xing-Fu

    2017-05-24

    The oriental armyworm Mythimna separate is an economically important insect with a wide distribution and strong migratory activity. However, knowledge about the molecular mechanisms regulating the physiological and behavioural responses of the oriental armyworm is scarce. In the present study, we took a transcriptomic approach to characterize the gene network in the adult head of M. separate. The sequencing and de novo assembly yielded 63,499 transcripts, which were further assembled into 46,459 unigenes with an N50 of 1,153 bp. In the head transcriptome data, unigenes involved in the 'signal transduction mechanism' are the most abundant. In total, 937 signal transduction unigenes were assigned to 22 signalling pathways. The circadian clock, melanin synthesis, and non-receptor protein of olfactory gene families were then identified, and phylogenetic analyses were performed with these M. separate genes, the model insect Bombyx mori and other insects. Furthermore, 1,372 simple sequence repeats of 2-6 bp in unit length were identified. The transcriptome data represent a comprehensive molecular resource for the adult head of M. separate, and these identified genes can be valid targets for further gene function research to address the molecular mechanisms regulating the migratory and olfaction genes of the oriental armyworm.

  10. 17 CFR 230.485 - Effective date of post-effective amendments filed by certain registered investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-end management investment company, unit investment trust or separate account as defined in section 2(a... Commission, having due regard to the public interest and the protection of investors, may declare an... by a registered open-end management investment company, unit investment trust or separate account as...

  11. 40 CFR 63.1567 - What are my requirements for inorganic HAP emissions from catalytic reforming units?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... reactors in the catalytic reforming unit are regenerated in separate regeneration systems, then these emission limitations apply to each separate regeneration system. These emission limitations apply to... rejuvenation operations during coke burn-off and catalyst regeneration. You can choose from the two options in...

  12. To Segregate or to Separate? Special Education Expansion and Divergence in the United States and Germany

    ERIC Educational Resources Information Center

    Powell, Justin J. W.

    2009-01-01

    Over the past two hundred years in the United States and Germany, special educational systems have been institutionalized to facilitate access to learning opportunities for children with disabilities, difficulties, and disadvantages. Originally heralded as innovative, the positive views of these mainly segregating and separating educational…

  13. Reduce oil and grease content in wastewater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Capps, R.W.; Matelli, G.N.; Bradford, M.L.

    Poor water quality is often blamed on biological oxidation unit malfunction. However, poorly treated water entering the bio-unit is more often the problem. At the microscopic level, oil/water-separation dynamics are influenced by pH, fluid velocity, temperature, and unit volumes. Oily water's physical and chemical properties affect pretreatment systems such as API separators, corrugated plate interception (CPI) separators, air flotation and equalization systems. A better understanding of pretreatment systems' limits and efficiencies can improve wastewater quality before it upsets the biological oxidation (BIOX). Oil contamination in refinery wastewater originates from desalting, steam stripping, product treating, tank drains, sample drains and equipmentmore » washdown. The largest volumetric contributors are cooling tower blowdowns and contaminated stormwater. The paper describes the BIOX process; oil/water separation; oil/water emulsions and colloidal solutions; air flotation; surfactants; DAF (dissolved air flotation) process; IAF (induced air flotation) process; equalization; load factors; salts; and system design.« less

  14. Effect of preoperative oral midazolam sedation on separation anxiety and emergence delirium among children undergoing dental treatment under general anesthesia.

    PubMed

    El Batawi, Hisham Yehia

    2015-01-01

    To investigate the possible effects of preoperative oral Midazolam on parental separation anxiety, emergence delirium, and post-anesthesia care unit time on children undergoing dental rehabilitation under general anesthesia. Randomized, prospective, double-blind study. Seventy-eight American Society of Anesthesiology (ASA) I children were divided into two groups of 39 each. Children of the first group were premedicated with oral Midazolam 0.5 mg/kg, while children of the control group were premedicated with a placebo. Scores for parental separation, mask acceptance, postoperative emergence delirium, and time spent in the post-anesthesia care unit were compared statistically. The test group showed significantly lower parental separation scores and high acceptance rate for anesthetic mask. There was no significant difference between the two groups regarding emergence delirium and time spent in post-anesthesia care unit. Preoperative oral Midazolam could be a useful adjunct in anxiety management for children suffering dental anxiety. The drug may not reduce the incidence of postoperative emergence delirium. The suggested dose does not seem to affect the post-anesthesia care unit time.

  15. Evaluation of target efficiencies for solid-liquid separation steps in biofuels production.

    PubMed

    Kochergin, Vadim; Miller, Keith

    2011-01-01

    Development of liquid biofuels has entered a new phase of large scale pilot demonstration. A number of plants that are in operation or under construction face the task of addressing the engineering challenges of creating a viable plant design, scaling up and optimizing various unit operations. It is well-known that separation technologies account for 50-70% of both capital and operating cost. Additionally, reduction of environmental impact creates technological challenges that increase project cost without adding to the bottom line. Different technologies vary in terms of selection of unit operations; however, solid-liquid separations are likely to be a major contributor to the overall project cost. Despite the differences in pretreatment approaches, similar challenges arise for solid-liquid separation unit operations. A typical process for ethanol production from biomass includes several solid-liquid separation steps, depending on which particular stream is targeted for downstream processing. The nature of biomass-derived materials makes it either difficult or uneconomical to accomplish complete separation in a single step. Therefore, setting realistic efficiency targets for solid-liquid separations is an important task that influences overall process recovery and economics. Experimental data will be presented showing typical characteristics for pretreated cane bagasse at various stages of processing into cellulosic ethanol. Results of generic material balance calculations will be presented to illustrate the influence of separation target efficiencies on overall process recoveries and characteristics of waste streams.

  16. Turbulent boundary layer separation over a rearward facing ramp and its control through mechanical excitation

    NASA Technical Reports Server (NTRS)

    Mckinzie, Daniel J., Jr.

    1991-01-01

    A vane oscillating about a fixed point at the inlet to a two-dimensional 20 degree rearward facing ramp has proven effective in delaying the separation of a turbulent boundary layer. Measurements of the ramp surface static pressure coefficient obtained under the condition of vane oscillation and constant inlet velocity revealed that two different effects occurred with surface distance along the ramp. In the vicinity of the oscillating vane, the pressure coefficients varied as a negative function of the vane's trailing edge rms velocity; the independent variable on which the rms velocity depends are the vane's oscillation frequency and its displacement amplitude. From a point downstream of the vane to the exit of the ramp; however, the pressure coefficient varied as a more complex function of the two independent variables. That is, it was found to vary as a function of the vane's oscillation frequency throughout the entire range of frequencies covered during the test, but over only a limited range of the trailing edge displacement amplitudes covered. More specifically, the value of the pressure coefficient was independent of increases in the vane's displacement amplitude above approximately 35 inner wall units of the boundary layer. Below this specific amplitude it varied as a function of the vane's trailing edge rms velocity. This height is close to the upper limit of the buffer layer. A parametric study was made to determine the variation of the maximum static pressure recovery as a function of the vane's oscillation frequency, for several ramp inlet velocities and a constant displacement amplitude of the vane's trailing edge. The results indicate that the phenomenon producing the optimum delay of separation may be Strouhal number dependent. Corona anemometer measurements obtained in the inner wall regions of the boundary layer for the excited case reveal a large range of unsteadiness in the local velocities. These measurements imply the existence of inflections in the profiles, which provide a mechanism for resulting inviscid flow instabilities to produce turbulence in the near wall region, thereby delaying separation of the boundary layer.

  17. Selenium and rutin alone or in combination do not have stronger protective effects than their separate effects against cadmium-induced renal damage.

    PubMed

    Abarikwu, Sunny O; Adebayo, Olusegun L; Otuechere, Chiagoziem A; Iserhienrhien, Blessing O; Badejo, Temitope A

    2016-01-01

    Selenium (Se) and rutin (RUT) are antioxidants that protect against tissue damage. In this study, the separate and combine protective effects of RUT and Se against cadmium (Cd)-induced renal damage were evaluated in rats. Wistar rats were treated by gavage to RUT (30 mg/kg) or Se (0.15 ppm) or Cd (200 ppm) in drinking water alone or in combination (30 mg/kg RUT +0.15 ppm Se + 200 ppm Cd). Corn oil was used as vehicle (2 mL/kg). After a 5-week treatment period, rat kidneys were removed for biochemical assays and histopathological examination. Se and Cd levels were evaluated by flame atomic absorption spectrophotometry. The malondialdehyde and glutathione levels as well as superoxide dismutase and catalase activities in the Cd-treated animals were increased compared with control values (0.056 ± 0.0003 versus 0.011 ± 0.0005 μmol/mg; 0.005 ± 0.0006 versus 0.00085 ± 0.0002 μg/mg; 1.62 ± 0.09 versus 0.48 ± 0.12 units/mg; 650 ± 25 versus 361.89 ± 31 μmol H2O2/mg, respectively). Cd treatment was also associated with decreased renal Se concentration (4.19 ± 0.92 versus 7.73 ± 0.7 μg/g dry weight), increased alkaline phosphatase (0.07 ± 0.0015 versus 0.033 ± 0.0019 unit/mg), acid phosphatase (0.029 ± 0.0021 versus 0.015 ± 0.0016 unit/mg), and lactate dehydrogenase (0.032 ± 0.004 versus 0.014 ± 0.0027 unit/mg) activities, respectively, and with evidence of severe renal damage. The combination of RUT and Se or their separate effects prevented the Cd-induced oxidative renal damage. However, their combine effects do not have stronger effects than their separate effect against Cd-induced renal damage. RUT and Se function as potent antioxidant in the protection of renal damage induced by Cd.

  18. High-Pressure Open-Channel On-Chip Electroosmotic Pump for Nanoflow High Performance Liquid Chromatography

    PubMed Central

    2015-01-01

    Here, we construct an open-channel on-chip electroosmotic pump capable of generating pressures up to ∼170 bar and flow rates up to ∼500 nL/min, adequate for high performance liquid chromatographic (HPLC) separations. A great feature of this pump is that a number of its basic pump units can be connected in series to enhance its pumping power; the output pressure is directly proportional to the number of pump units connected. This additive nature is excellent and useful, and no other pumps can work in this fashion. We demonstrate the feasibility of using this pump to perform nanoflow HPLC separations; tryptic digests of bovine serum albumin (BSA), transferrin factor (TF), and human immunoglobulins (IgG) are utilized as exemplary samples. We also compare the performance of our electroosmotic (EO)-driven HPLC with Agilent 1200 HPLC; comparable efficiencies, resolutions, and peak capacities are obtained. Since the pump is based on electroosmosis, it has no moving parts. The common material and process also allow this pump to be integrated with other microfabricated functional components. Development of this high-pressure on-chip pump will have a profound impact on the advancement of lab-on-a-chip devices. PMID:24495233

  19. An optimized top contact design for solar cell concentrators

    NASA Technical Reports Server (NTRS)

    Desalvo, Gregory C.; Barnett, Allen M.

    1985-01-01

    A new grid optimization scheme is developed for point focus solar cell concentrators which employs a separated grid and busbar concept. Ideally, grid lines act as the primary current collectors and receive all of the current from the semiconductor region. Busbars are the secondary collectors which pick up current from the grids and carry it out of the active region of the solar cell. This separation of functions leads to a multithickness metallization design, where the busbars are made larger in cross section than the grids. This enables the busbars to carry more current per unit area of shading, which is advantageous under high solar concentration where large current densities are generated. Optimized grid patterns using this multilayer concept can provide a 1.6 to 20 percent increase in output power efficiency over optimized single thickness grids.

  20. Skylab Rescue Space Vehicle OAT No. 1 Plugs in Test

    NASA Technical Reports Server (NTRS)

    Jevitt, S. J.

    1973-01-01

    A test is described which demonstrates the compatibility of the Skylab Rescue Space Vehicle systems, the ground support equipment, and off-site support facilities by proceeding through a simulated launch countdown, liftoff, and flight. The functions of propellant loading, umbilical ejection, holddown arm release, service arm retraction, liftoff, and inflight separation are simulated. An external power source supplies transfer power to internal, and instrument unit commands are simulated by the digital command system. The test outline is presented along with a list of references, intercommunications information, radio frequency matrix, and interface control chart.

  1. Analytical study of electrical disconnect system for use on manned and unmanned missions

    NASA Technical Reports Server (NTRS)

    Rosener, A. A.; Lenda, J. A.; Trummer, R. O.; Jonkoniec, T. G.

    1977-01-01

    The program to survey existing electrical connector availability, and establish an optimum connector design for maintainable spacecraft substation interfaces is reported. Functional and operational requirements are given along with the results of the documentation survey, which disclosed that the MSFC series connectors have the preferred features of current connector technology. Optimum design concepts for EVA tasks, modules serviced by manipulators, and for manipulators independent of other servicing units are presented. It is concluded that separate connector designs are required for spacecraft replaceable modules, and for crewman EVA.

  2. Inorganic nanotubes and fullerenes . Structure and properties of hypothetical phosphorus fullerenes

    NASA Astrophysics Data System (ADS)

    Seifert, G.; Heine, T.; Fowler, P. W.

    The possibility of stable non-carbon fullerenes is discussed for the case of phosphorus fullerene-like cage structures. On the basis of Density Functional Tight Binding calculations it is shown that many such cages correspond to metastable structures, but with increasing nuclearity become less stable with respect to separate molecular P4 units. Stability rules, known for carbon fullerenes, such as the ``isolated pentagon rule'', do not reflect the different electronic and steric requirements of the phosphorus atom. The computational results tend to rule out phosphorus fullerenes.

  3. In situ self cross-linking of polyvinyl alcohol battery separators

    NASA Technical Reports Server (NTRS)

    Philipp, W. H.; Hsu, L. C.; Sheibley, D. W. (Inventor)

    1979-01-01

    A battery separator was produced from a polyvinyl alcohol sheet structure which was subjected to an in situ, self crosslinking process by selective oxidation of the 1,2 diol units present in the polyvinyl alcohol sheet structure. The 1,2 diol units were cleaved to form aldehyde end groups which subsequently crosslink through acetalization of the 1,3 diol units of the polyvinyl alcohol. Selective oxidation was achieved using a solution of a suitable oxidizing agent such as periodic acid or lead tetraacetate.

  4. Microbial and Functional Diversity within the Phyllosphere of Espeletia Species in an Andean High-Mountain Ecosystem.

    PubMed

    Ruiz-Pérez, Carlos A; Restrepo, Silvia; Zambrano, María Mercedes

    2016-01-08

    Microbial populations residing in close contact with plants can be found in the rhizosphere, in the phyllosphere as epiphytes on the surface, or inside plants as endophytes. Here, we analyzed the microbiota associated with Espeletia plants, endemic to the Páramo environment of the Andes Mountains and a unique model for studying microbial populations and their adaptations to the adverse conditions of high-mountain neotropical ecosystems. Communities were analyzed using samples from the rhizosphere, necromass, and young and mature leaves, the last two analyzed separately as endophytes and epiphytes. The taxonomic composition determined by performing sequencing of the V5-V6 region of the 16S rRNA gene indicated differences among populations of the leaf phyllosphere, the necromass, and the rhizosphere, with predominance of some phyla but only few shared operational taxonomic units (OTUs). Functional profiles predicted on the basis of taxonomic affiliations differed from those obtained by GeoChip microarray analysis, which separated community functional capacities based on plant microenvironment. The identified metabolic pathways provided insight regarding microbial strategies for colonization and survival in these ecosystems. This study of novel plant phyllosphere microbiomes and their putative functional ecology is also the first step for future bioprospecting studies in search of enzymes, compounds, or microorganisms relevant to industry or for remediation efforts. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  5. Microbial and Functional Diversity within the Phyllosphere of Espeletia Species in an Andean High-Mountain Ecosystem

    PubMed Central

    Restrepo, Silvia

    2016-01-01

    Microbial populations residing in close contact with plants can be found in the rhizosphere, in the phyllosphere as epiphytes on the surface, or inside plants as endophytes. Here, we analyzed the microbiota associated with Espeletia plants, endemic to the Páramo environment of the Andes Mountains and a unique model for studying microbial populations and their adaptations to the adverse conditions of high-mountain neotropical ecosystems. Communities were analyzed using samples from the rhizosphere, necromass, and young and mature leaves, the last two analyzed separately as endophytes and epiphytes. The taxonomic composition determined by performing sequencing of the V5-V6 region of the 16S rRNA gene indicated differences among populations of the leaf phyllosphere, the necromass, and the rhizosphere, with predominance of some phyla but only few shared operational taxonomic units (OTUs). Functional profiles predicted on the basis of taxonomic affiliations differed from those obtained by GeoChip microarray analysis, which separated community functional capacities based on plant microenvironment. The identified metabolic pathways provided insight regarding microbial strategies for colonization and survival in these ecosystems. This study of novel plant phyllosphere microbiomes and their putative functional ecology is also the first step for future bioprospecting studies in search of enzymes, compounds, or microorganisms relevant to industry or for remediation efforts. PMID:26746719

  6. Single chain technology: Toward the controlled synthesis of polymer nanostructures

    NASA Astrophysics Data System (ADS)

    Lyon, Christopher

    A technique for fabricating advanced polymer nanostructures enjoying recent popularity is the collapse or folding of single polymer chains in highly dilute solution mediated by intramolecular cross-linking. We term the resultant structures single-chain nanoparticles (SCNP). This technique has proven particularly valuable in the synthesis of nanomaterials on the order of 5 -- 20 nm. Many different types of covalent and non-covalent chemistries have been used to this end. This dissertation investigates the use of so-called single-chain technology to synthesize nanoparticles using modular techniques that allow for easy incorporation of functionality or special structural or characteristic features. Specifically, the synthesis of linear polymers functionalized with pendant monomer units and the subsequent intramolecular polymerization of these monomer units is discussed. In chapter 2, the synthesis of SCNP using alternating radical polymerization is described. Polymers functionalized with pendant styrene and stilbene groups are synthesized via a modular post-polymerization Wittig reaction. These polymers were exposed to radical initiators in the presence (and absence) of maleic anhydride and other electron deficient monomers in order to form intramolecular cross-links. Chapter 3 discusses templated acyclic diene metathesis (ADMET) polymerization using single-chain technology, starting with the controlled ring-opening polymerization of a glycidyl ether functionalized with an ADMET monomer. This polymer was then exposed to Grubbs' catalyst to polymerize the ADMET monomer units. The ADMET polymer was hydrolytically cleaved from the template and separated. Upon characterization, it was found that the daughter ADMET polymer had a similar degree of polymerization, but did not retain the low dispersity of the template. Chapter 4 details the synthesis of aldehyde- and diol-functionalized polymers toward the synthesis of SCNP containing dynamic, acid-degradable acetal cross-links. SCNP fabrication with these materials is beyond the scope of this dissertation.

  7. SEM analysis of ionizing radiation effects in an analog to digital converter /AD571/

    NASA Technical Reports Server (NTRS)

    Gauthier, M. K.; Perret, J.; Evans, K. C.

    1981-01-01

    The considered investigation is concerned with the study of the total-dose degradation mechanisms in an IIL analog to digital (A/D) converter. The A/D converter is a 10 digit device having nine separate functional units on the chip which encompass several hundred transistors and circuit elements. It was the objective of the described research to find the radiation sensitive elements by a systematic search of the devices on the LSI chip. The employed technique using a scanning electron microscope to determine the functional blocks of an integrated circuit which are sensitive to ionizing radiation and then progressively zeroing in on the soft components within those blocks, proved extremely successful on the AD571. Four functional blocks were found to be sensitive to radiation, including the Voltage Reference, DAC, IIL Clock, and IIL SAR.

  8. Aggregation in complex triacylglycerol oils: coarse-grained models, nanophase separation, and predicted x-ray intensities.

    PubMed

    Quinn, Bonnie; Peyronel, Fernanda; Gordon, Tyler; Marangoni, Alejandro; Hanna, Charles B; Pink, David A

    2014-11-19

    Triacylglycerols (TAGs) are biologically important molecules which form crystalline nanoplatelets (CNPs) and, ultimately, fat crystal networks in edible oils. Characterizing the self-assembled hierarchies of these networks is important to understanding their functionality and oil binding capacity. We have modelled CNPs in multicomponent oils and studied their aggregation. The oil comprises (a) a liquid component, and (b) components which phase separately on a nano-scale (nano-phase separation) to coat the surfaces of the CNPs impenetrably, either isotropically or anisotropically, with either liquid-like coatings or crystallites, forming a coating of thickness ?. We modelled three cases: (i) liquid?liquid nano-phase separation, (ii) solid?liquid nano-phase separation, with CNPs coated isotropically, and (iii) CNPs coated anisotropically. The models were applied to mixes of tristearin and triolein with fully hydrogenated canola oil, shea butter with high oleic sunflower oil, and cotton seed oil. We performed Monte Carlo simulations, computed structure functions and concluded: (1) three regimes arose: (a) thin coating regime, Δ < 0.0701 u (b) transition regime, 0.0701 u ≤ Δ ≤ 0.0916 u and (c) thick coating regime, Δ > 0.0916 u. (arbitrary units, u) (2) The thin coating regime exhibits 1D TAGwoods, which aggregate, via DLCA/RLCA, into fractal structures which are uniformly distributed in space. (3) In the thick coating regime, for an isotropic coating, TAGwoods are not formed and coated CNPs will not aggregate but will be uniformly distributed in space. For anisotropic coating, TAGwoods can be formed and might form 1D strings but will not form DLCA/RLCA clusters. (4) The regimes are, approximately: thin coating, 0 < Δ < 7.0 nm transition regime, 7.0 < Δ < 9.2 nm and thick coating, Δ > 9.2 nm (5) The minimum minority TAG concentration required to undergo nano-phase separation is, approximately, 0.29% (thin coatings) and 0.94% (thick coatings). Minority components can have substantial effects upon aggregation for concentrations less than 1%.

  9. Threshold setting by the surround of cat retinal ganglion cells.

    PubMed

    Barlow, H B; Levick, W R

    1976-08-01

    1. The slope of curves relating the log increment threshold to log background luminance in cat retinal ganglion cells is affected by the area and duration of the test stimulus, as it is in human pyschophysical experiments. 2. Using large area, long duration stimuli the slopes average 0-82 and approach close to 1 (Weber's Law) in the steepest cases. Small stimuli gave an average of 0-53 for on-centre units using brief stimuli, and 0-56 for off-centre units, using long stimuli. Slopes under 0-5 (square root law) were not found over an extended range of luminances. 3. On individual units the slope was generally greater for larger and longer test stimulus, but no unit showed the full extent of change from slope of 0-5 to slope of 1. 4. The above differences hold for objective measures of quantum/spike ratio, as well as for thresholds either judged by ear or assessed by calculation. 5. The steeper slope of the curves for large area, long duration test stimuli compared with small, long duration stimuli, is associated with the increased effectiveness of antagonism from the surround at high backgrounds. This change may be less pronounced in off-centre units, one of which (probably transient Y-type) showed no difference of slope, and gave parallel area-threshold curves at widely separated background luminances, confirming the importance of differential surround effectiveness in changing the slope of the curves. 6. In on-centre units, the increased relative effectiveness of the surround is associated with the part of the raised background light that falls on the receptive field centre. 7. It is suggested that the variable surround functions as a zero-offset control that sets the threshold excitation required for generating impulses, and that this is separate from gain-setting adaptive mechanisms. This may be how ganglion cells maintain high incremental sensitivity in spite of a strong maintained excitatory drive that would otherwise cause compressive response non-linearities.

  10. 24 CFR 884.122 - Separate project requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... separate ACC List and ACC Part I and shall be assigned a separate project number. All new construction... construction projects where: (1) The units are placed under ACC on the same date; and (2) Such consolidation is...

  11. 24 CFR 884.122 - Separate project requirement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... separate ACC List and ACC Part I and shall be assigned a separate project number. All new construction... construction projects where: (1) The units are placed under ACC on the same date; and (2) Such consolidation is...

  12. Interventional Radiation Oncology (IRO): Transition of a magnetic resonance simulator to a brachytherapy suite.

    PubMed

    Anderson, Roberta; Armour, Elwood; Beeckler, Courtney; Briner, Valerie; Choflet, Amanda; Cox, Andrea; Fader, Amanda N; Hannah, Marie N; Hobbs, Robert; Huang, Ellen; Kiely, Marilyn; Lee, Junghoon; Morcos, Marc; McMillan, Paige E; Miller, Dave; Ng, Sook Kien; Prasad, Rashmi; Souranis, Annette; Thomsen, Robert; DeWeese, Theodore L; Viswanathan, Akila N

    As a core component of a new gynecologic cancer radiation program, we envisioned, structured, and implemented a novel Interventional Radiation Oncology (IRO) unit and magnetic resonance (MR)-brachytherapy environment in an existing MR simulator. We describe the external and internal processes required over a 6-8 month time frame to develop a clinical and research program for gynecologic brachytherapy and to successfully convert an MR simulator into an IRO unit. Support of the institution and department resulted in conversion of an MR simulator to a procedural suite. Development of the MR gynecologic brachytherapy program required novel equipment, staffing, infrastructural development, and cooperative team development with anesthetists, nurses, therapists, physicists, and physicians to ensure a safe and functional environment. Creation of a separate IRO unit permitted a novel billing structure. The creation of an MR-brachytherapy environment in an MR simulator is feasible. Developing infrastructure includes several collaborative elements. Unique to the field of radiation oncology, formalizing the space as an Interventional Radiation Oncology unit permits a sustainable financial structure. Copyright © 2018 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  13. Comparison of Separation Shock for Explosive and Nonexplosive Release Actuators on a Small Spacecraft Panel

    NASA Technical Reports Server (NTRS)

    Lucy, M. H.; Buehrle, R. D.; Woolley, J. P.

    1996-01-01

    Functional shock, safety, overall system costs, and emergence of new technologies, have raised concerns regarding continued use of pyrotechnics on spacecraft. NASA Headquarters-Office of Chief Engineer requested Langley Research Center (LaRC) study pyrotechnic alternatives using non-explosive actuators (NEA's), and LARC participated with Lockheed Martin Missile and Space Co. (LMMSC)-Sunnyvale, CA in objectively evaluating applicability of some NEA mechanisms to reduce small spacecraft and booster separation event shock. Comparative tests were conducted on a structural simulator using five different separation nut mechanisms, consisting of three pyrotechnics from OEA-Aerospace and Hi-Shear Technology and two NEA's from G&H Technology and Lockheed Martin Astronautics (LMA)-Denver, CO. Multiple actuations were performed with preloads up to 7000 pounds, 7000 being the comparison standard. All devices except LMA's NEA rotary flywheel-nut concept were available units with no added provisions to attenuate shock. Accelerometer measurements were recorded, reviewed, processed into Shock Response Spectra (SRS), and comparisons performed. For the standard preload, pyrotechnics produced the most severe and the G&H NEA the least severe functional shock levels. Comparing all results, the LMA concept produced the lowest levels, with preload limited to approximately 4200 pounds. Testing this concept over a range of 3000 to 4200 pounds indicated no effect of preload on shock response levels. This report presents data from these tests and the comparative results.

  14. Microphase separation of comb copolymers with two different lengths of side chains

    NASA Astrophysics Data System (ADS)

    Aliev, M. A.; Kuzminyh, N. Yu.

    2009-10-01

    The phase behavior of the monodisperse AB comb copolymer melt contained the macromolecules of special architecture is discussed. Each macromolecule is assumed to be composed of two comb blocks which differ in numbers of side chains and numbers of monomer units in these chains. It is shown (by analysis of the structure factor of the melt) that microphase separation at two different length scales in the melt is possible. The large and small length scales correspond to separation between comb blocks and separation between monomer units in repeating fragments of blocks, respectively. The classification diagrams indicated which length scale is favored for a given parameters of chemical structure of macromolecules are constructed.

  15. Towards improved estimation of the unsaturated soil hydraulic conductivity in the near saturated range by a fully automated, pressure controlled unit gradient experiment.

    NASA Astrophysics Data System (ADS)

    Werisch, Stefan; Müller, Marius

    2017-04-01

    Determination of soil hydraulic properties has always been an important part of soil physical research and model applications. While several experiments are available to measure the water retention of soil samples, the determination of the unsaturated hydraulic conductivity is often more complicated, bound to strong assumption and time consuming. Although, the application of unit gradient experiments is recommended since the middle of the last century, as one method towards a (assumption free) direct measurement of the unsaturated hydraulic conductivity, data from unit gradient experiments is seldom to never reported in literature. We developed and build a fully automated, pressure controlled, unit gradient experiment, which allows a precise determination of the unsaturated soil hydraulic conductivity K(h) and water retention VWC(h), especially in the highly dynamic near saturated range. The measurement apparatus applies the concept of hanging water columns and imposes the required soil water pressure by dual porous plates. This concepts allows the simultaneous and direct measurement of water retention and hydraulic conductivity. Moreover, this approach results in a technically less demanding experiment than related flux controlled experiments, and virtually any flux can be measured. Thus, both soil properties can be measured in mm resolution, for wetting and drying processes, between saturation and field capacity for all soil types. Our results show, that it is important to establish separate measurements of the unsaturated hydraulic conductivity in the near saturated range, as the shape of the retention function and hydraulic conductivity curve do not necessarily match. Consequently, the prediction of the hydraulic conductivity curve from measurements of the water retention behavior in combination with a value for the saturated hydraulic conductivity can be misleading. Thus, separate parameterizations of the individual functions might be necessary and are possible with this approach. Furthermore, the apparatus allows a convenient quantification of temperature effects on both hydraulic properties and first results demonstrate impressively the important role of temperature on hydraulic conductivity, which is notoriously underestimated.

  16. The Evolution of the Multiplicity of Embedded Protostars. II. Binary Separation Distribution and Analysis

    NASA Astrophysics Data System (ADS)

    Connelley, Michael S.; Reipurth, Bo; Tokunaga, Alan T.

    2008-06-01

    We present the Class I protostellar binary separation distribution based on the data tabulated in a companion paper. We verify the excess of Class I binary stars over solar-type main-sequence stars in the separation range from 500 AU to 4500 AU. Although our sources are in nearby star-forming regions distributed across the entire sky (including Orion), none of our objects are in a high stellar density environment. A log-normal function, used by previous authors to fit the main-sequence and T Tauri binary separation distributions, poorly fits our data, and we determine that a log-uniform function is a better fit. Our observations show that the binary separation distribution changes significantly during the Class I phase, and that the binary frequency at separations greater than 1000 AU declines steadily with respect to spectral index. Despite these changes, the binary frequency remains constant until the end of the Class I phase, when it drops sharply. We propose a scenario to account for the changes in the Class I binary separation distribution. This scenario postulates that a large number of companions with a separation greater than ~1000 AU were ejected during the Class 0 phase, but remain gravitationally bound due to the significant mass of the Class I envelope. As the envelope dissipates, these companions become unbound and the binary frequency at wide separations declines. Circumstellar and circumbinary disks are expected to play an important role in the orbital evolution at closer separations. This scenario predicts that a large number of Class 0 objects should be non-hierarchical multiple systems, and that many Class I young stellar objects (YSOs) with a widely separated companion should also have a very close companion. We also find that Class I protostars are not dynamically pristine, but have experienced dynamical evolution before they are visible as Class I objects. Our analysis shows that the Class I binary frequency and the binary separation distribution strongly depend on the star-forming environment. The Infrared Telescope Facility is operated by the University of Hawaii under Cooperative Agreement no. NCC 5-538 with the National Aeronautics and Space Administration, Science Mission Directorate, Planetary Astronomy Program. The United Kingdom Infrared Telescope is operated by the Joint Astronomy Centre on behalf of the Science and Technology Facilities Council of the U.K. Based in part on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

  17. Desegregation of Public Schools. Testimony before the Subcommittee on Separation of Powers, Committee on the Judiciary, United States Senate.

    ERIC Educational Resources Information Center

    Reynolds, William Bradford

    This testimony was delivered by William Bradford Reynolds, the Assistant Attorney General of the Civil Rights Division, before the Subcommttee on Separation of Powers, Committee on the Judiciary of the United States Senate. Reynold states that compulsory busing of students is not an acceptable remedy to achieve racial balance. He emphasizes the…

  18. 26 CFR 1.614-8 - Elections with respect to separate operating mineral interests for taxable years beginning after...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Natural Resources § 1.614-8 Elections with respect to... interests, participates in a unit or pool, such part shall, for the period of its participation in the unit or pool, be treated for purposes of this section as being separate from the nonparticipating portion...

  19. 26 CFR 1.614-8 - Elections with respect to separate operating mineral interests for taxable years beginning after...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Natural Resources § 1.614-8 Elections with respect to... interests, participates in a unit or pool, such part shall, for the period of its participation in the unit or pool, be treated for purposes of this section as being separate from the nonparticipating portion...

  20. Effect of preoperative oral midazolam sedation on separation anxiety and emergence delirium among children undergoing dental treatment under general anesthesia

    PubMed Central

    El Batawi, Hisham Yehia

    2015-01-01

    Aim: To investigate the possible effects of preoperative oral Midazolam on parental separation anxiety, emergence delirium, and post-anesthesia care unit time on children undergoing dental rehabilitation under general anesthesia. Methods: Randomized, prospective, double-blind study. Seventy-eight American Society of Anesthesiology (ASA) I children were divided into two groups of 39 each. Children of the first group were premedicated with oral Midazolam 0.5 mg/kg, while children of the control group were premedicated with a placebo. Scores for parental separation, mask acceptance, postoperative emergence delirium, and time spent in the post-anesthesia care unit were compared statistically. Results: The test group showed significantly lower parental separation scores and high acceptance rate for anesthetic mask. There was no significant difference between the two groups regarding emergence delirium and time spent in post-anesthesia care unit. Conclusions: Preoperative oral Midazolam could be a useful adjunct in anxiety management for children suffering dental anxiety. The drug may not reduce the incidence of postoperative emergence delirium. The suggested dose does not seem to affect the post-anesthesia care unit time. PMID:25992332

  1. High-performance dual-speed CCD camera system for scientific imaging

    NASA Astrophysics Data System (ADS)

    Simpson, Raymond W.

    1996-03-01

    Traditionally, scientific camera systems were partitioned with a `camera head' containing the CCD and its support circuitry and a camera controller, which provided analog to digital conversion, timing, control, computer interfacing, and power. A new, unitized high performance scientific CCD camera with dual speed readout at 1 X 106 or 5 X 106 pixels per second, 12 bit digital gray scale, high performance thermoelectric cooling, and built in composite video output is described. This camera provides all digital, analog, and cooling functions in a single compact unit. The new system incorporates the A/C converter, timing, control and computer interfacing in the camera, with the power supply remaining a separate remote unit. A 100 Mbyte/second serial link transfers data over copper or fiber media to a variety of host computers, including Sun, SGI, SCSI, PCI, EISA, and Apple Macintosh. Having all the digital and analog functions in the camera made it possible to modify this system for the Woods Hole Oceanographic Institution for use on a remote controlled submersible vehicle. The oceanographic version achieves 16 bit dynamic range at 1.5 X 105 pixels/second, can be operated at depths of 3 kilometers, and transfers data to the surface via a real time fiber optic link.

  2. Identification of different geologic units using fuzzy constrained resistivity tomography

    NASA Astrophysics Data System (ADS)

    Singh, Anand; Sharma, S. P.

    2018-01-01

    Different geophysical inversion strategies are utilized as a component of an interpretation process that tries to separate geologic units based on the resistivity distribution. In the present study, we present the results of separating different geologic units using fuzzy constrained resistivity tomography. This was accomplished using fuzzy c means, a clustering procedure to improve the 2D resistivity image and geologic separation within the iterative minimization through inversion. First, we developed a Matlab-based inversion technique to obtain a reliable resistivity image using different geophysical data sets (electrical resistivity and electromagnetic data). Following this, the recovered resistivity model was converted into a fuzzy constrained resistivity model by assigning the highest probability value of each model cell to the cluster utilizing fuzzy c means clustering procedure during the iterative process. The efficacy of the algorithm is demonstrated using three synthetic plane wave electromagnetic data sets and one electrical resistivity field dataset. The presented approach shows improvement on the conventional inversion approach to differentiate between different geologic units if the correct number of geologic units will be identified. Further, fuzzy constrained resistivity tomography was performed to examine the augmentation of uranium mineralization in the Beldih open cast mine as a case study. We also compared geologic units identified by fuzzy constrained resistivity tomography with geologic units interpreted from the borehole information.

  3. The clinical anatomy of the insertion of the rotator cuff tendons.

    PubMed

    Vosloo, M; Keough, N; De Beer, M A

    2017-04-01

    The rotator cuff (RC) insertions according to most anatomical texts are described as being separate from one another. However, clear fusion of the RC tendon fibres exists with prior studies showing this interdigitation forming a common, continuous insertion onto and around the lesser and greater tubercles (LT and GT) of the humerus. Current surgical repair methods (especially arthroscopic techniques) rarely mention or consider these connections during repair and suture anchor implantation. The general principles of RC surgery remain a controversial subject, due to various available techniques, surgeon experience and preference, and the contradicting success rates. This results from old-fashioned knowledge of the anatomy of the RC complex and its functional aspects. Therefore, the purpose of this project was to visualise and define the RC footprint and extension insertions with the aim of enhancing and improving knowledge of the basic anatomy in the hopes that this will be considered during orthopaedic repair. Twenty shoulders (16 cadaveric and 4 fresh) were used in the study. The fresh shoulders were received from the National Tissue Bank, and ethical clearance was obtained (239/2015). Reverse dissection was performed to better visualise the RC unit exposing the interdigitated rotator hood (extension insertions), as well as the complete RC unit (tendons + internal capsule) separated from the scapula and humerus. Once the insertions were exposed and documented, the RC muscle footprint (articular surface area) was measured and recorded, using AutoCAD 2016. No statistical significant difference between left and right (p = 0.424) was noted, but a significant difference between males and females (p = 0.000) was. Collectively, these findings indicate and strengthen evidence towards the notion that the RC muscles/tendons and the internal capsule are one complete and inseparable unit/complex. The fact that the RC unit is more complex in its structure and attachment places importance on the biomechanical stresses encountered after repair. Functions of one RC muscle are not necessarily isolated but instead can be influenced by surrounding muscles as well. In addition to providing greater understanding of the basic anatomy of the RC unit, these findings also provide clarity for surgeons with the goal of improving and enhancing surgical methods for better post-operative patient outcome.

  4. Discovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response

    PubMed Central

    Potyrailo, Radislav A.; Starkey, Timothy A.; Vukusic, Peter; Ghiradella, Helen; Vasudev, Milana; Bunning, Timothy; Naik, Rajesh R.; Tang, Zhexiong; Larsen, Michael; Deng, Tao; Zhong, Sheng; Palacios, Manuel; Grande, James C.; Zorn, Gilad; Goddard, Gregory; Zalubovsky, Sergey

    2013-01-01

    For almost a century, the iridescence of tropical Morpho butterfly scales has been known to originate from 3D vertical ridge structures of stacked periodic layers of cuticle separated by air gaps. Here we describe a biological pattern of surface functionality that we have found in these photonic structures. This pattern is a gradient of surface polarity of the ridge structures that runs from their polar tops to their less-polar bottoms. This finding shows a biological pattern design that could stimulate numerous technological applications ranging from photonic security tags to self-cleaning surfaces, gas separators, protective clothing, sensors, and many others. As an important first step, this biomaterial property and our knowledge of its basis has allowed us to unveil a general mechanism of selective vapor response observed in the photonic Morpho nanostructures. This mechanism of selective vapor response brings a multivariable perspective for sensing, where selectivity is achieved within a single chemically graded nanostructured sensing unit, rather than from an array of separate sensors. PMID:24019497

  5. Chiral separation of terbutaline and non-steroidal anti-inflammatory drugs by using a new lysine-bridged hemispherodextrin in capillary electrophoresis.

    PubMed

    Cucinotta, V; Messina, M; Contino, A; Maccarrone, G; Orlandini, S; Giuffrida, A

    2017-10-25

    A method for the separation of a mixture of terbutaline and non-steroidal anti-inflammatory drugs was developed using capillary electrophoresis with a new hemispherodextrin, ad hoc designed, the lysine - bridged hemispherodextrin (THLYSH). The use of lysine residues to bridge the trehalose capping unit moiety to the cyclodextrin cavity gives rise to a receptor with two long chains with amine nitrogen atoms, whose charge can be easily tuned as a function of the solution pH. The new hemispherodextrin was accurately characterised by ESI-MS and NMR spectroscopy, also highlighting its protonation behaviour. Circular dichroism and ESR spectroscopy measurements were also carried out to test its inclusion ability towards anthraquinone-3-sulfonate and its metal coordination ability towards copper(II) ion, respectively. Analogously to the other hemispherodextrins, the main skill of this new derivative lies in its chiral selector properties, as shown by the separation of the enantiomeric pairs of terbutaline and ibuprofen, flurbiprofen, suprofen and tiaprofenic acid by capillary electrophoresis. The focused use of the solution equilibria involved in the separations made it possible to understand the phenomena occurring in solution, and to finely tune the charge status of the receptor. In this way the chiral separation of the racemic mixture was successfully obtained, even if the receptor was individually used, differently by the other hemispherodextrins previously studied whose chiral separation capabilities are present only if used as binary mixtures. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Motor unit number estimation and quantitative needle electromyography in stroke patients.

    PubMed

    Kouzi, Ioanna; Trachani, Eftichia; Anagnostou, Evangelos; Rapidi, Christina-Anastasia; Ellul, John; Sakellaropoulos, George C; Chroni, Elisabeth

    2014-12-01

    To evaluate the effect of upper motor neuron damage upon motor units' function by means of two separate and supplementary electrophysiological methods. The abductor digiti minimi muscle of the non-paretic and the paretic side was studied in forty-six stroke patients with (a) motor unit number estimation (MUNE) - adapted multiple point stimulation method and (b) computerized quantitative needle electromyography (EMG) assessing the configuration of voluntary recruited motor unit potentials. Main outcome comparisons were focused on differences between non-paretic and paretic side. On the affected hands mean MUNE value was significantly lower and mean area of the surface recorded single motor unit potentials was significantly larger than the corresponding ones on the non-paretic hands. EMG findings did not reveal remarkable differences between the two sides. Neither severity nor chronicity of stroke was related to MUNE or EMG parameters. MUNE results, which suggested reduced motor unit numbers in stroke patients, in conjunction with the normal EMG features in these same muscles has given rise to different interpretations. In a clinical setting, reinnervation type changes in the EMG similar to that occurring in neuronopathies or axonal neuropathies should not be expected in muscles with central neurogenic lesion. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Compact CFB: The next generation CFB boiler

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Utt, J.

    1996-12-31

    The next generation of compact circulating fluidized bed (CFB) boilers is described in outline form. The following topics are discussed: compact CFB = pyroflow + compact separator; compact CFB; compact separator is a breakthrough design; advantages of CFB; new design with substantial development history; KUHMO: successful demo unit; KUHMO: good performance over load range with low emissions; KOKKOLA: first commercial unit and emissions; KOKKOLA: first commercial unit and emissions; compact CFB installations; next generation CFB boiler; grid nozzle upgrades; cast segmented vortex finders; vortex finder installation; ceramic anchors; pre-cast vertical bullnose; refractory upgrades; and wet gunning.

  8. Alternative meiotic chromatid segregation in the holocentric plant Luzula elegans

    PubMed Central

    Heckmann, Stefan; Jankowska, Maja; Schubert, Veit; Kumke, Katrin; Ma, Wei; Houben, Andreas

    2014-01-01

    Holocentric chromosomes occur in a number of independent eukaryotic lineages. They form holokinetic kinetochores along the entire poleward chromatid surfaces, and owing to this alternative chromosome structure, species with holocentric chromosomes cannot use the two-step loss of cohesion during meiosis typical for monocentric chromosomes. Here we show that the plant Luzula elegans maintains a holocentric chromosome architecture and behaviour throughout meiosis, and in contrast to monopolar sister centromere orientation, the unfused holokinetic sister centromeres behave as two distinct functional units during meiosis I, resulting in sister chromatid separation. Homologous non-sister chromatids remain terminally linked after metaphase I, by satellite DNA-enriched chromatin threads, until metaphase II. They then separate at anaphase II. Thus, an inverted sequence of meiotic sister chromatid segregation occurs. This alternative meiotic process is most likely one possible adaptation to handle a holocentric chromosome architecture and behaviour during meiosis. PMID:25296379

  9. 10 CFR 2.348 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Separation of functions. 2.348 Section 2.348 Energy... Adjudicatory Hearings § 2.348 Separation of functions. (a) In any proceeding under this part, any NRC officer or employee engaged in the performance of any investigative or litigating function in the proceeding...

  10. 20 CFR 404.1220 - Identification numbers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... numbers for payroll record units. SSA assigns, at a State's request, unit numbers to payroll record units within a State or political subdivision. When a State requests separate payroll record unit numbers, it must furnish the following: (1) The name of each payroll record unit for the coverage group; and (2...

  11. KSC-97pc655

    NASA Image and Video Library

    1997-04-16

    An oxygen generator destined to replace a malfunctioning unit on the Russian Mir Space Station is the object of much curiosity during preflight preparations in the SPACEHAB Payload Processing Facility. A SPACEHAB Double Module on the Space Shuttle Atlantis will carry the oxygen generator to Mir during STS-84, the sixth Shuttle-Mir docking. The nearly 300-pound generator, manufactured by RSC Energia in Russia, will replace one of two Mir units that have been malfunctioning recently. The generator functions by electrolysis, which separates water into its oxygen and hydrogen components. The hydrogen is vented and the oxygen is used for breathing by the Mir crew. The generator is 4.2 feet in length and 1.4 feet in diameter. STS-84, which is planned to include a Mir crew exchange of astronaut C. Michael Foale for Jerry M. Linenger, is targeted for a May 15 liftoff

  12. [Improvement of controlling system by a separated medical unit of special purpose].

    PubMed

    Shelepov, A M; Savchenko, I F; Zhidik, V V; Gogolevskiĭ, A S

    2009-11-01

    The article presents a variant securing of field treatment institutes by mobile command points in combination with creation of automated system of control of a separated medical unit of special purpose and improvement of communications devices, computing and relaying of data. Such improvement of system of control permits to solve governmental tasks and make decision more effective, spending less time.

  13. 26 CFR 1.6013-6 - Election to treat nonresident alien individual as resident of the United States.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reason of the individual's domicile, residence, or citizenship. Under article 4 (1) of the treaty, W is a... both the United States and country X by reason of article 4 (1), the individual shall be deemed to be a... spouses legally separate under a degree of divorce or of separate maintenance. An election that terminates...

  14. Electrodeionization method

    DOEpatents

    Lin, YuPo J.; Hestekin, Jamie; Arora, Michelle; St. Martin, Edward J.

    2004-09-28

    An electrodeionization method for continuously producing and or separating and/or concentrating ionizable organics present in dilute concentrations in an ionic solution while controlling the pH to within one to one-half pH unit method for continuously producing and or separating and/or concentrating ionizable organics present in dilute concentrations in an ionic solution while controlling the pH to within one to one-half pH unit.

  15. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  16. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  17. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  18. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  19. 40 CFR 60.1065 - What must I include in my draft materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false What must I include in my draft... Requirements: Materials Separation Plan § 60.1065 What must I include in my draft materials separation plan? (a) You must prepare and submit a draft materials separation plan for your municipal waste combustion unit...

  20. Maximising profits for an EPQ model with unreliable machine and rework of random defective items

    NASA Astrophysics Data System (ADS)

    Pal, Brojeswar; Sankar Sana, Shib; Chaudhuri, Kripasindhu

    2013-03-01

    This article deals with an economic production quantity (EPQ) model in an imperfect production system. The production system may undergo in 'out-of-control' state from 'in-control' state, after a certain time that follows a probability density function. The density function varies with reliability of the machinery system that may be controlled by new technologies, investing more costs. The defective items produced in 'out-of-control' state are reworked at a cost just after the regular production time. Occurrence of the 'out-of-control' state during or after regular production-run time is analysed and also graphically illustrated separately. Finally, an expected profit function regarding the inventory cost, unit production cost and selling price is maximised analytically. Sensitivity analysis of the model with respect to key parameters of the system is carried out. Two numerical examples are considered to test the model and one of them is illustrated graphically.

  1. Differential Effect of Left vs. Right White Matter Hyperintensity Burden on Functional Decline: The Northern Manhattan Study.

    PubMed

    Dhamoon, Mandip S; Cheung, Ying-Kuen; Bagci, Ahmet; Alperin, Noam; Sacco, Ralph L; Elkind, Mitchell S V; Wright, Clinton B

    2017-01-01

    Asymmetry of brain dysfunction may disrupt brain network efficiency. We hypothesized that greater left-right white matter hyperintensity volume (WMHV) asymmetry was associated with functional trajectories. Methods: In the Northern Manhattan Study, participants underwent brain MRI with axial T1, T2, and fluid attenuated inversion recovery sequences, with baseline interview and examination. Volumetric WMHV distribution across 14 brain regions was determined separately by combining bimodal image intensity distribution and atlas based methods. Participants had annual functional assessments with the Barthel index (BI, range 0-100) over a mean of 7.3 years. Generalized estimating equations (GEE) models estimated associations of regional WMHV and regional left-right asymmetry with baseline BI and change over time, adjusted for baseline medical risk factors, sociodemographics, and cognition, and stroke and myocardial infarction during follow-up. Results: Among 1,195 participants, greater WMHV asymmetry in the parietal lobes (-8.46 BI points per unit greater WMHV on the right compared to left, 95% CI -3.07, -13.86) and temporal lobes (-2.48 BI points, 95% CI -1.04, -3.93) was associated with lower overall function. Greater WMHV asymmetry in the parietal lobes (-1.09 additional BI points per year per unit greater WMHV on the left compared to right, 95% CI -1.89, -0.28) was independently associated with accelerated functional decline. Conclusions: In this large population-based study with long-term repeated measures of function, greater regional WMHV asymmetry was associated with lower function and functional decline. In addition to global WMHV, WHMV asymmetry may be an important predictor of long-term functional status.

  2. Separation of In-Vitro-Derived Megakaryocytes and Platelets Using Spinning-Membrane Filtration

    PubMed Central

    Schlinker, Alaina C.; Radwanski, Katherine; Wegener, Christopher; Min, Kyungyoon; Miller, William M.

    2015-01-01

    In-vitro-derived platelets (PLTs) could potentially overcome problems associated with donated PLTs, including contamination and alloimmunization. Although several groups have produced functional PLTs from stem cells in vitro, the challenge of developing this technology to yield transfusable PLT units has yet to be addressed. The asynchronous nature of in vitro PLT generation makes a single harvest point infeasible for collecting PLTs as soon as they are formed. The current standard of performing manual centrifugations to separate PLTs from nucleated cells at multiple points during culture is labor-intensive, imprecise, and difficult to standardize in accordance with current Good Manufacturing Practices (cGMP). In an effort to develop a more effective method, we adapted a commercially-available, spinning-membrane filtration device to separate in-vitro-derived PLTs from nucleated cells and recover immature megakaryocytes (MKs), the precursor cells to PLTs, for continued culture. Processing a mixture of in-vitro-derived MKs and PLTs on the adapted device yielded a pure PLT population and did not induce PLT pre-activation. MKs recovered from the separation process were unaffected with respect to viability and ploidy, and were able to generate PLTs after reseeding in culture. Being able to efficiently harvest in-vitro-derived PLTs brings this technology one step closer to clinical relevance. PMID:25312394

  3. Effects of flow separation and cove leakage on pressure and heat-transfer distributions along a wing-cove-elevon configuration at Mach 6.9. [Langley 8-ft high temperature tunnel test

    NASA Technical Reports Server (NTRS)

    Deveikis, W. D.

    1983-01-01

    External and internal pressure and cold-wall heating-rate distributions were obtained in hypersonic flow on a full-scale heat-sink representation of the space shuttle orbiter wing-elevon-cove configuration in an effort to define effects of flow separation on cove aerothermal environment as a function of cove seal leak area, ramp angle, and free-stream unit Reynolds number. Average free-stream Mach number from all tests was 6.9; average total temperature from all tests was 3360 R; free-stream dynamic pressure ranged from about 2 to 9 psi; and wing angle of attack was 5 deg (flow compression). For transitional and turbulent flow separation, increasing cove leakage progressively increased heating rates in the cove. When ingested mass flow was sufficient to force large reductions in extent of separation, increasing cove leakage reduced heating rates in the cove to those for laminar attached flow. Cove heating-rate distributions calculated with a method that assumed laminar developing channel flow agreed with experimentally obtained distributions within root-mean-square differences that varied between 11 and 36 percent where cove walls were parallel for leak areas of 50 and 100 percent.

  4. Vortex tube can increase liquid hydrocarbon recovery at plant inlet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hajdik, B.; Lorey, M.; Steinle, J.

    1997-09-08

    Use of a vortex-tube device yields improved inlet gas-liquid separation, when compared with a Joule-Thomson system, but is less costly and complex than a true isentropic system, such as a turboexpander. Because the vortex-tube unit provides separation as well as pressure reduction, the capital cost of a Joule-Thomson system with valve and separator will be similar to that of the vortex-tube system. Future applications of vortex-tube units will be concentrated where performance improvements over Joule-Thomson units, at low capital cost, are required. The operating characteristics of a vortex tube permit gas, in part, to be reduced in temperature to lessmore » than that normally achievable through isenthalpic expansion. The following three examples show how vortex technology can be applied to achieve these aims.« less

  5. Moisture Separator Reheater for NPP Turbines

    NASA Astrophysics Data System (ADS)

    Manabe, Jun; Kasahara, Jiro

    This paper introduces the development of the current model Moisture Separator Reheater (MSR) for nuclear power plant (NPP) turbines, commercially placed in service in the period 1984-1997, focusing on the mist separation performance of the MSR along with drainage from heat exchanger tubes. A method of predicting the mist separation performance was devised first based on the observation of mist separation behaviors under an air-water test. Then the method was developed for the application to predict under the steam conditions, followed by the verification in comparison with the actual results of a steam condition test. The instability of tube drainage associated with both sub-cooling and temperature oscillation might adversely affect the seal welding of tubes to tube sheet due to thermal fatigue. The instability was measured on an existing unit to clarify behaviors and the development of a method to suppress them. Both methods were applied to newly constructed units and the effectiveness of the methods was demonstrated.

  6. Functional mapping of the pelvic floor and sphincter muscles from high-density surface EMG recordings.

    PubMed

    Peng, Yun; He, Jinbao; Khavari, Rose; Boone, Timothy B; Zhang, Yingchun

    2016-11-01

    Knowledge of the innervation of pelvic floor and sphincter muscles is of great importance to understanding the pathophysiology of female pelvic floor dysfunctions. This report presents our high-density intravaginal and intrarectal electromyography (EMG) probes and a comprehensive innervation zone (IZ) imaging technique based on high-density EMG readings to characterize the IZ distribution. Both intravaginal and intrarectal probes are covered with a high-density surface electromyography electrode grid (8 × 8). Surface EMG signals were acquired in ten healthy women performing maximum voluntary contractions of their pelvic floor. EMG decomposition was performed to separate motor-unit action potentials (MUAPs) and then localize their IZs. High-density surface EMG signals were successfully acquired over the vaginal and rectal surfaces. The propagation patterns of muscle activity were clearly visualized for multiple muscle groups of the pelvic floor and anal sphincter. During each contraction, up to 218 and 456 repetitions of motor units were detected by the vaginal and rectal probes, respectively. MUAPs were separated with their IZs identified at various orientations and depths. The proposed probes are capable of providing a comprehensive mapping of IZs of the pelvic floor and sphincter muscles. They can be employed as diagnostic and preventative tools in clinical practices.

  7. Extremal values of the sojourn time

    NASA Astrophysics Data System (ADS)

    Astaburuaga, M. A.; Cortés, V. H.; Duclos, P.

    2010-11-01

    Consider a self-adjoint operator H on a separable Hilbert space \\ {H} with non-trivial absolutely continuous component. We study the general properties of the real-valued functional, \\tau _{H}(\\psi )=\\int _{{\\ R}}|(e^{-itH}\\psi,\\psi )|^2\\,dt, which in quantum mechanics represents the sojourn time (or life time) of an initial state \\psi \\in \\ {H}. We characterize the critical points of the sojourn time, τX, of the operator multiplication by x in L^2({\\ R}), and prove that it attains a global maximum in the unit sphere of the Sobolev space \\ {W}^{1,2}({\\ R}).

  8. Brainstem origins for cortical 'what' and 'where' pathways in the auditory system.

    PubMed

    Kraus, Nina; Nicol, Trent

    2005-04-01

    We have developed a data-driven conceptual framework that links two areas of science: the source-filter model of acoustics and cortical sensory processing streams. The source-filter model describes the mechanics behind speech production: the identity of the speaker is carried largely in the vocal cord source and the message is shaped by the ever-changing filters of the vocal tract. Sensory processing streams, popularly called 'what' and 'where' pathways, are well established in the visual system as a neural scheme for separately carrying different facets of visual objects, namely their identity and their position/motion, to the cortex. A similar functional organization has been postulated in the auditory system. Both speaker identity and the spoken message, which are simultaneously conveyed in the acoustic structure of speech, can be disentangled into discrete brainstem response components. We argue that these two response classes are early manifestations of auditory 'what' and 'where' streams in the cortex. This brainstem link forges a new understanding of the relationship between the acoustics of speech and cortical processing streams, unites two hitherto separate areas in science, and provides a model for future investigations of auditory function.

  9. Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions.

    PubMed

    Czuba, Ewelina; Steliga, Aleksandra; Lietzau, Grażyna; Kowiański, Przemysław

    2017-08-01

    The brain, demanding constant level of cholesterol, precisely controls its synthesis and homeostasis. The brain cholesterol pool is almost completely separated from the rest of the body by the functional blood-brain barrier (BBB). Only a part of cholesterol pool can be exchanged with the blood circulation in the form of the oxysterol metabolites such, as 27-hydroxycholesterol (27-OHC) and 24S-hydroxycholesterol (24S-OHC). Not only neurons but also blood vessels and neuroglia, constituting neurovascular unit (NVU), are crucial for the brain cholesterol metabolism and undergo precise regulation by numerous modulators, metabolites and signal molecules. In physiological conditions maintaining the optimal cholesterol concentration is important for the energetic metabolism, composition of cell membranes and myelination. However, a growing body of evidence indicates the consequences of the cholesterol homeostasis dysregulation in several pathophysiological processes. There is a causal relationship between hypercholesterolemia and 1) development of type 2 diabetes due to long-term high-fat diet consumption, 2) significance of the oxidative stress consequences for cerebral amyloid angiopathy and neurodegenerative diseases, 3) insulin resistance on progression of the neurodegenerative brain diseases. In this review, we summarize the current state of knowledge concerning the cholesterol influence upon functioning of the NVU under physiological and pathological conditions.

  10. Effects of Clown Doctors on Child and Caregiver Anxiety at the Entrance to the Surgery Care Unit and Separation from Caregivers

    ERIC Educational Resources Information Center

    Arriaga, Patrícia; Pacheco, Catarina

    2016-01-01

    This study investigated the effects of hospital Clown Doctors intervention on child and caregiver preoperative anxiety at the entrance to the surgery care unit and separation from caregivers. A total of 88 children (aged 4-12 years) were assigned to one of the following two groups: Clown Doctors intervention or control group (standard care).…

  11. Chameleon-like elastomers with molecularly encoded strain-adaptive stiffening and coloration

    NASA Astrophysics Data System (ADS)

    Vatankhah-Varnosfaderani, Mohammad; Keith, Andrew N.; Cong, Yidan; Liang, Heyi; Rosenthal, Martin; Sztucki, Michael; Clair, Charles; Magonov, Sergei; Ivanov, Dimitri A.; Dobrynin, Andrey V.; Sheiko, Sergei S.

    2018-03-01

    Active camouflage is widely recognized as a soft-tissue feature, and yet the ability to integrate adaptive coloration and tissuelike mechanical properties into synthetic materials remains elusive. We provide a solution to this problem by uniting these functions in moldable elastomers through the self-assembly of linear-bottlebrush-linear triblock copolymers. Microphase separation of the architecturally distinct blocks results in physically cross-linked networks that display vibrant color, extreme softness, and intense strain stiffening on par with that of skin tissue. Each of these functional properties is regulated by the structure of one macromolecule, without the need for chemical cross-linking or additives. These materials remain stable under conditions characteristic of internal bodily environments and under ambient conditions, neither swelling in bodily fluids nor drying when exposed to air.

  12. A Spatiotemporal-Chaos-Based Cryptosystem Taking Advantage of Both Synchronous and Self-Synchronizing Schemes

    NASA Astrophysics Data System (ADS)

    Lü, Hua-Ping; Wang, Shi-Hong; Li, Xiao-Wen; Tang, Guo-Ning; Kuang, Jin-Yu; Ye, Wei-Ping; Hu, Gang

    2004-06-01

    Two-dimensional one-way coupled map lattices are used for cryptography where multiple space units produce chaotic outputs in parallel. One of the outputs plays the role of driving for synchronization of the decryption system while the others perform the function of information encoding. With this separation of functions the receiver can establish a self-checking and self-correction mechanism, and enjoys the advantages of both synchronous and self-synchronizing schemes. A comparison between the present system with the system of advanced encryption standard (AES) is presented in the aspect of channel noise influence. Numerical investigations show that our system is much stronger than AES against channel noise perturbations, and thus can be better used for secure communications with large channel noise.

  13. A Small-Scale Low-Cost Gas Chromatograph

    ERIC Educational Resources Information Center

    Gros, Natasa; Vrtacnik, Margareta

    2005-01-01

    The design and application of a small-scale portable gas chromatograph for learning of the basic concepts of chromatography is described. The apparatus consists of two basic separable units, which includes a chromatographic unit and an electronic unit.

  14. Prospective Prediction of Functional Difficulties among Recently Separated Veterans

    DTIC Science & Technology

    2014-01-01

    while factors following separation from the military have a primary role in predicting functional difficulties during reintegration into civilian...and protective factors for functional difficulties among Veterans. In a sample of recently separated Marines, we used stepwise logistic and multiple...military, posttraumatic stress disorder, prospective, PTSD, reintegration, risk factors , Veterans, work functioning . INTRODUCTION Studies suggest that Iraq

  15. 40 CFR 63.1561 - Am I subject to this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Standards for Hazardous Air Pollutants for Petroleum Refineries: Catalytic Cracking Units, Catalytic..., and fuel oils), or lubricants; (ii) Separating petroleum; or (iii) Separating, cracking, reacting, or...

  16. 40 CFR 63.1561 - Am I subject to this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for Hazardous Air Pollutants for Petroleum Refineries: Catalytic Cracking Units, Catalytic..., and fuel oils), or lubricants; (ii) Separating petroleum; or (iii) Separating, cracking, reacting, or...

  17. The effects of common medical interventions on pain, back function, and work resumption in patients with chronic low back pain: A prospective 2-year cohort study in six countries.

    PubMed

    Hansson, T H; Hansson, E K

    2000-12-01

    A prospective cohort study with identical questionnaires and inclusion criteria was performed. To compare in six different countries the frequencies and effects of the common medical interventions used for patients with low back pain who are work incapacitated. Low back pain is a huge problem with increasing costs for health care, industry, and society. Cohorts of employed men and women ages 18 to 59 years who had been sick-listed (100%) for a minimum of 90 days because of low back pain were recruited in Denmark, Germany, Israel, Sweden, the Netherlands, and the United States. The subjects received three separate questionnaires with identical questions after 90 days, 1 year, and 2 years. The questionnaires included separate questions about background factors, treatment, and the like, as well as validated scales such as the Hannover Activities of Daily Living, von Korff pain score, Short Form-36, and Karasek-Theorell. Working status was obtained from registers. Main outcome measures were working/not working, back function, and pain. All three questionnaires were completed by 2080 subjects in the six countries. With few exceptions, there were great similarities in the appointments, examinations, and treatments in the different countries. Considerable differences were found between the back surgery rates, which ranged from 6% in Sweden to 32% in the United States during the first 90 days of the study. Very few of the interventions had any noticeable positive effects on work resumption, pain, or back function. Back surgery in Sweden was a striking exception, positively affecting all three outcome measures. The frequencies of work resumption within the first year ranged from 73% in the Netherlands to 32% in Denmark. Almost none of the commonly occurring and frequently practiced medical interventions for patients who are sick-listed because of low back pain had any positive effects on either the recorded health measures or work resumption.

  18. 6 CFR 13.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Separation of functions. 13.14 Section 13.14 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.14 Separation of functions. (a) The Investigating Official, the Reviewing Official, and any...

  19. 22 CFR 521.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Separation of functions. 521.14 Section 521.14 Foreign Relations BROADCASTING BOARD OF GOVERNORS IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 521.14 Separation of functions. (a) The investigating official, the reviewing official, and any...

  20. 22 CFR 224.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Separation of functions. 224.14 Section 224.14 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.14 Separation of functions. (a) The investigating official, the reviewing official, and any...

  1. Article separation apparatus and method for unit operations

    DOEpatents

    Pardini, Allan F.; Gervais, Kevin L.; Mathews, Royce A.; Hockey, Ronald L.

    2010-06-22

    An apparatus and method are disclosed for separating articles from a group of articles. The apparatus includes a container for containing one or more articles coupled to a suitable fluidizer for suspending articles within the container and transporting articles to an induction tube. A portal in the induction tube introduces articles singly into the induction tube. A vacuum pulls articles through the induction tube separating the articles from the group of articles in the container. The apparatus and method can be combined with one or more unit operations or modules, e.g., for inspecting articles, assessing quality of articles, or ascertaining material properties and/or parameters of articles, including layers thereof.

  2. Simulation of a Novel Single-column Cryogenic Air Separation Process Using LNG Cold Energy

    NASA Astrophysics Data System (ADS)

    Jieyu, Zheng; Yanzhong, Li; Guangpeng, Li; Biao, Si

    In this paper, a novel single-column air separation process is proposed with the implementation of heat pump technique and introduction of LNG coldenergy. The proposed process is verifiedand optimized through simulation on the Aspen Hysys® platform. Simulation results reveal that thepower consumption per unit mass of liquid productis around 0.218 kWh/kg, and the total exergy efficiency of the systemis 0.575. According to the latest literatures, an energy saving of 39.1% is achieved compared with those using conventional double-column air separation units.The introduction of LNG cold energy is an effective way to increase the system efficiency.

  3. 8 CFR 215.1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... is not a citizen or national of the United States. (b) The term Commissioner means the Commissioner... Alaska and Hawaii. (g) The term geographical part of the United States means: (1) The continental United... for any foreign place, or (2) from one geographical part of the United States for a separate...

  4. 8 CFR 215.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... is not a citizen or national of the United States. (b) The term Commissioner means the Commissioner... Alaska and Hawaii. (g) The term geographical part of the United States means: (1) The continental United... for any foreign place, or (2) from one geographical part of the United States for a separate...

  5. 8 CFR 215.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... is not a citizen or national of the United States. (b) The term Commissioner means the Commissioner... Alaska and Hawaii. (g) The term geographical part of the United States means: (1) The continental United... for any foreign place, or (2) from one geographical part of the United States for a separate...

  6. Lung function, atopy, specific hypersensitivity, and smoking of workers in the enzyme detergent industry over 11 years.

    PubMed

    Flood, D F; Blofeld, R E; Bruce, C F; Hewitt, J I; Juniper, C P; Roberts, D M

    1985-01-01

    A study of 2800 workers employed in three factories of the two major manufacturers of enzymatic products in the United Kingdom covering 11 years of operation from 1969 to 1980 showed that 2344 workers had sufficient lung function data to meet the operational criteria and these were analysed in three separate groups by factory locations. Spirometry and prick tests for specific skin reactions to standardised enzyme were performed at six monthly intervals for the first six years of the study and then annually. Factory enzyme dust and total dust measurements were made to determine the degree of dust exposure of the subjects. The lung function of the factory groups was analysed for the effects of working in the detergent industry, the degree of exposure to enzymes, skin prick test positivity to enzymes, atopicity, and smoking. The 4.5% of workers who had experienced respiratory effects from enzymes were analysed separately. Exposure to the enzyme allergen has had no significant long term effect on the lung function of the detergent workers. A higher proportion of atopics than non-atopics became skin test positive to the allergen and more smokers than non-smokers were sensitised. The overall lung function of detergent workers showed 39 ml/year loss in FEV1 on the 11 year longitudinal study and 51 ml/year loss on the lateral (cross sectional) analysis with better lung function in the south east than the north west of England. In the development of the methodology for the study several potential problems were discovered that could remain unrecognised in a cross sectional analysis performed in isolation.

  7. Centrifugal Sieve for Gravity-Level-Independent Size Segregation of Granular Materials

    NASA Technical Reports Server (NTRS)

    Walton, Otis R.; Dreyer, Christopher; Riedel, Edward

    2013-01-01

    Conventional size segregation or screening in batch mode, using stacked vibrated screens, is often a time-consuming process. Utilization of centrifugal force instead of gravity as the primary body force can significantly shorten the time to segregate feedstock into a set of different-sized fractions. Likewise, under reduced gravity or microgravity, a centrifugal sieve system would function as well as it does terrestrially. When vibratory and mechanical blade sieving screens designed for terrestrial conditions were tested under lunar gravity conditions, they did not function well. The centrifugal sieving design of this technology overcomes the issues that prevented sieves designed for terrestrial conditions from functioning under reduced gravity. These sieves feature a rotating outer (cylindrical or conical) screen wall, rotating fast enough for the centrifugal forces near the wall to hold granular material against the rotating screen. Conventional centrifugal sieves have a stationary screen and rapidly rotating blades that shear the granular solid near the stationary screen, and effect the sieving process assisted by the airflow inside the unit. The centrifugal sieves of this new design may (or may not) have an inner blade or blades, moving relative to the rotating wall screen. Some continuous flow embodiments would have no inner auger or blades, but achieve axial motion through vibration. In all cases, the shearing action is gentler than conventional centrifugal sieves, which have very high velocity differences between the stationary outer screen and the rapidly rotating blades. The new design does not depend on airflow in the sieving unit, so it will function just as well in vacuum as in air. One advantage of the innovation for batch sieving is that a batch-mode centrifugal sieve may accomplish the same sieving operation in much less time than a conventional stacked set of vibrated screens (which utilize gravity as the primary driving force for size separation). In continuous mode, the centrifugal sieves can provide steady streams of fine and coarse material separated from a mixed feedstock flow stream. The centrifugal sieves can be scaled to any desired size and/or mass flow rate. Thus, they could be made in sizes suitable for small robotic exploratory missions, or for semi-permanent processing of regolith for extraction of volatiles of minerals. An advantage of the continuous-mode system is that it can be made with absolutely no gravity flow components for feeding material into, or for extracting the separated size streams from, the centrifugal sieve. Thus, the system is capable of functioning in a true microgravity environment. Another advantage of the continuous-mode system is that some embodiments of the innovation have no internal blades or vanes, and thus, can be designed to handle a very wide range of feedstock sizes, including occasional very large oversized pieces, without jamming or seizing up.

  8. Nomenclature of regional hydrogeologic units of the Southeastern Coastal Plain aquifer system

    USGS Publications Warehouse

    Miller, J.A.; Renken, R.A.

    1988-01-01

    Clastic sediments of the Southeastern Coastal Plain aquifer system can be divided into four regional aquifers separated by three regional confining units. The four regional aquifers have been named for major rivers that cut across their outcrop areas and expose the aquifer materials. From youngest to oldest, the aquifers are called the Chickasawhay River, Pearl River, Chattahoochee River, and Black Warrior River aquifers, and the regional confining units separating them are given the same name as the aquifer they overlie. Most of the regional hydrogeologic units are subdivided within each of the four States that comprise the study area. Correlation of regional units is good with hydrogeologic units delineated by a similar regional study to the west and southwest. Because of complexity created by a major geologic structure to the northeast of the study area and dramatic facies change from clastic to carbonate strata to the southeast, correlation of regional hydrogeologic units is poor in these directions. (Author 's abstract)

  9. Long-Range Intramolecular Electronic Communication in a Trinuclear Ruthenium Tropolonate Complex.

    PubMed

    Yoshida, Jun; Kuwahara, Kyohei; Suzuki, Kota; Yuge, Hidetaka

    2017-02-20

    Dinuclear and trinuclear ruthenium complexes, [Ru(trop) 2 (C 2 trop)Ru(dppe)Cp] [2b; trop = tropolonato, C 2 trop = ethynyltropolonato, dppe = 1,2-bis(diphenylphosphino)ethane] and [Ru(trop){(C 2 trop)Ru(dppe)Cp} 2 ] (3), were synthesized, and their electronic and electrochemical properties were investigated in comparison with our previously reported complex [Ru(acac) 2 (C 2 trop)Ru(dppe)Cp] (2a). The electron-donating Ru II (dppe)Cp unit and electron-accepting Ru III O 6 unit are connected by C 2 trop in these complexes. 2a incorporates acetylacetonate as an ancillary ligand, while 2b and 3 incorporate tropolonate as an ancillary ligand. Every complex, 2a, 2b, and 3, exhibits similar UV-vis-near-IR (NIR) absorption spectra, demonstrating the lack of explicit intramolecular electronic communication between the units at least in the neutral state. The weak NIR absorption in 2a further diminished upon electrochemical oxidation, indicating almost no electronic communication between the units. In contrast, 2b and 3 exhibit broad NIR absorptions upon oxidation. Additionally, 3 exhibits four stepwise redox couples in the electrochemical study, which are formally attributed to [Ru II (trop) 3 ] - /[Ru III (trop) 3 ], two [Ru II (dppe)Cp]/[Ru III (dppe)Cp] + , and [Ru III (trop) 3 ]/[Ru IV (trop) 3 ] + couples. Clear separation of the redox couples attributed to the two terminal [Ru(dppe)Cp] units demonstrates the thermodynamic stability of the intermediate oxidation states with respect to disproportionation. Further electrochemical studies using an electrolyte including perfluorinated weakly coordinating anions and density functional theory/time-dependent density functional theory calculations confirmed the effect of ancillary ligands, acetylacetonate and tropolonate. In the case of 2a, electronic delocalization over the whole complex, especially over the [Ru(acac) 2 (trop)] unit, appears to be small. In contrast, the electronic communication between [Ru(dppe)Cp] and [Ru(trop) 3 ] units in 3 seems to be enhanced upon oxidation, resulting in the long-range intramolecular electronic communication.

  10. Carbon Dioxide Separation Using Thermally Optimized Membranes

    NASA Astrophysics Data System (ADS)

    Young, J. S.; Jorgensen, B. S.; Espinoza, B. F.; Weimer, M. W.; Jarvinen, G. D.; Greenberg, A.; Khare, V.; Orme, C. J.; Wertsching, A. K.; Peterson, E. S.; Hopkins, S. D.; Acquaviva, J.

    2002-05-01

    The purpose of this project is to develop polymeric-metallic membranes for carbon dioxide separations that operate under a broad range of industrially relevant conditions not accessible with present membrane units. The last decade has witnessed a dramatic increase in the use of polymer membranes as an effective, economic and flexible tool for many commercial gas separations including air separation, the recovery of hydrogen from nitrogen, carbon monoxide, and methane mixtures, and the removal of carbon dioxide from natural gas. In each of these applications, high fluxes and excellent selectivities have relied on glassy polymer membranes which separate gases based on both size and solubility differences. To date, however, this technology has focused on optimizing materials for near ambient conditions. The development of polymeric materials that achieve the important combination of high selectivity, high permeability, and mechanical stability at temperatures significantly above 25oC and pressures above 10 bar, respectively, has been largely ignored. Consequently, there is a compelling rationale for the exploration of a new realm of polymer membrane separations. Indeed, the development of high temperature polymeric-metallic composite membranes for carbon dioxide separation at temperatures of 100-450 oC and pressures of 10-150 bar would provide a pivotal contribution with both economic and environmental benefits. Progress to date includes the first ever fabrication of a polymeric-metallic membrane that is selective from room temperature to 370oC. This achievement represents the highest demonstrated operating temperature at which a polymeric based membrane has successfully functioned. Additionally, we have generated the first polybenzamidizole silicate molecular composites. Finally, we have developed a technique that has enabled the first-ever simultaneous measurements of gas permeation and membrane compaction at elevated temperatures. This technique provides a unique approach to the optimization of long-term membrane performance under challenging operating conditions.

  11. 33 CFR 20.206 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Separation of functions. 20.206 Section 20.206 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL RULES... Administrative Law Judges § 20.206 Separation of functions. (a) No ALJ may be responsible to, or supervised or...

  12. 34 CFR 33.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Separation of functions. 33.14 Section 33.14 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.14 Separation of functions. (a) The investigating official, the reviewing official, and any employee or agent of the...

  13. 10 CFR 13.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Separation of functions. 13.14 Section 13.14 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.14 Separation of functions. (a) The investigating official, the reviewing official, and any employee or agent of the authority who takes part in...

  14. 10 CFR 13.14 - Separation of functions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Separation of functions. 13.14 Section 13.14 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.14 Separation of functions. (a) The investigating official, the reviewing official, and any employee or agent of the authority who takes part in...

  15. 22 CFR 35.14 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Separation of functions. 35.14 Section 35.14 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.14 Separation of functions. (a) The investigating official, the reviewing official, and any employee or agent of...

  16. Rapid pupil-based assessment of glaucomatous damage.

    PubMed

    Chen, Yanjun; Wyatt, Harry J; Swanson, William H; Dul, Mitchell W

    2008-06-01

    To investigate the ability of a technique employing pupillometry and functionally-shaped stimuli to assess loss of visual function due to glaucomatous optic neuropathy. Pairs of large stimuli, mirror images about the horizontal meridian, were displayed alternately in the upper and lower visual field. Pupil diameter was recorded and analyzed in terms of the "contrast balance" (relative sensitivity to the upper and lower stimuli), and the pupil constriction amplitude to upper and lower stimuli separately. A group of 40 patients with glaucoma was tested twice in a first session, and twice more in a second session, 1 to 3 weeks later. A group of 40 normal subjects was tested with the same protocol. Results for the normal subjects indicated functional symmetry in upper/lower retina, on average. Contrast balance results for the patients with glaucoma differed from normal: half the normal subjects had contrast balance within 0.06 log unit of equality and 80% had contrast balance within 0.1 log unit. Half the patients had contrast balances more than 0.1 log unit from equality. Patient contrast balances were moderately correlated with predictions from perimetric data (r = 0.37, p < 0.00001). Contrast balances correctly classified visual field damage in 28 patients (70%), and response amplitudes correctly classified 24 patients (60%). When contrast balance and response amplitude were combined, receiver operating characteristic area for discriminating glaucoma from normal was 0.83. Pupillary evaluation of retinal asymmetry provides a rapid method for detecting and classifying visual field defects. In this patient population, classification agreed with perimetry in 70% of eyes.

  17. Rapid Pupil-Based Assessment of Glaucomatous Damage

    PubMed Central

    Chen, Yanjun; Wyatt, Harry J.; Swanson, William H.; Dul, Mitchell W.

    2010-01-01

    Purpose To investigate the ability of a technique employing pupillometry and functionally-shaped stimuli to assess loss of visual function due to glaucomatous optic neuropathy. Methods Pairs of large stimuli, mirror images about the horizontal meridian, were displayed alternately in the upper and lower visual field. Pupil diameter was recorded and analyzed in terms of the “contrast balance” (relative sensitivity to the upper and lower stimuli), and the pupil constriction amplitude to upper and lower stimuli separately. A group of 40 patients with glaucoma was tested twice in a first session, and twice more in a second session, 1 to 3 weeks later. A group of 40 normal subjects was tested with the same protocol. Results Results for the normal subjects indicated functional symmetry in upper/lower retina, on average. Contrast balance results for the patients with glaucoma differed from normal: half the normal subjects had contrast balance within 0.06 log unit of equality and 80% had contrast balance within 0.1 log unit. Half the patients had contrast balances more than 0.1 log unit from equality. Patient contrast balances were moderately correlated with predictions from perimetric data (r = 0.37, p < 0.00001). Contrast balances correctly classified visual field damage in 28 patients (70%), and response amplitudes correctly classified 24 patients (60%). When contrast balance and response amplitude were combined, receiver operating characteristic area for discriminating glaucoma from normal was 0.83. Conclusions Pupillary evaluation of retinal asymmetry provides a rapid method for detecting and classifying visual field defects. In this patient population, classification agreed with perimetry in 70% of eyes. PMID:18521026

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huskey, A.; Bowen, A.; Jager, D.

    This test was conducted as part of the U.S. Department of Energy's (DOE) Independent Testing project. This project was established to help reduce the barriers to wind energy expansion by providing independent testing results for small wind turbines (SWT). In total, five turbines were tested at the National Wind Technology Center (NWTC) as a part of this project. Safety and function testing is one of up to five tests performed on the turbines, including power performance, duration, noise, and power-quality tests. NWTC testing results provide manufacturers with reports that may be used to meet part of small wind turbine certificationmore » requirements. The test equipment includes a Mariah Windspire wind turbine mounted on a monopole tower. L&E Machine manufactured the turbine in the United States. The inverter was manufactured separately by Technology Driven Products in the United States. The system was installed by the NWTC site operations group with guidance and assistance from Mariah Power.« less

  19. Functional subdivisions in low-frequency primary auditory cortex (AI).

    PubMed

    Wallace, M N; Palmer, A R

    2009-04-01

    We wished to test the hypothesis that there are modules in low-frequency AI that can be identified by their responsiveness to communication calls or particular regions of space. Units were recorded in anaesthetised guinea pig AI and stimulated with conspecific vocalizations and a virtual motion stimulus (binaural beats) presented via a closed sound system. Recording tracks were mainly oriented orthogonally to the cortical surface. Some of these contained units that were all time-locked to the structure of the chutter call (14/22 tracks) and/or the purr call (12/22 tracks) and/or that had a preference for stimuli from a particular region of space (8/20 tracks with four contralateral, two ipsilateral and two midline), or where there was a strong asymmetry in the response to beats of different direction (two tracks). We conclude that about half of low-frequency AI is organized into modules that are consistent with separate "what" and "where" pathways.

  20. Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes.

    PubMed

    Li, Qian; Chen, Jun; Li, Ti; Liu, Chengmei; Zhai, Yuxin; McClements, David Julian; Liu, Jiyan

    2015-12-01

    Bioactive proanthocyanidins were isolated from the peel of Choerospondias axillaris fruit, which is a waste product of the food processing industry. Compositional analysis indicated that the proanthocyanidins had extension units mainly consisting of epicatechin gallate or epicatechin, and terminal units mainly consisting of catechin. Numerous polymeric forms of the molecules were detected, including monomers, dimers, and trimers. Certain fractions exhibited strong α-amylase or α-glucosidase inhibition in a dose-dependent manner. Furthermore, their inhibitory activities depended on their degree of polymerization and galloylation. For example, the most bioactive fraction had α-amylase and α-glucosidase inhibitory activities (IC50 values) of 541 and 3.1 μg mL(-1), respectively. This study demonstrates that proanthocyanidins from C. axillaris peels can inhibit carbohydrate digestive enzymes in vitro and may therefore serve as antidiabetic ingredients in functional or medical foods.

  1. Spacesuit guidebook

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This guidebook is designed to supplement the Spacesuit wall chart (WAL-114) published by the Education Affairs Division, January 1990. The wall chart depicts Astronaut Bruce McCandless on his historic first untethered spacewalk using the manned maneuvering unit. He flew on Shuttle mission 41-B, and ventured 100 meters for the Shuttle's cargo bay and returned safely. This guidebook explains in depth the elements depicted on the wall chart in see-through and cut-away perspectives. Together the wall chart and guidebook show as well as explain the inside workings of the spacesuit and its various components. Forty separate elements are identified with an accompanying numerical legend. Those elements are further explained in this guidebook along with their functions and how they work in relation to other elements. Additional chapters discuss essential components of the spacesuit such as the primary life support system and the manned maneuvering unit, and the method for donning the spacesuit.

  2. STS-84 oxygen generator for Mir on display at SPACEHAB

    NASA Technical Reports Server (NTRS)

    1997-01-01

    An oxygen generator destined to replace a malfunctioning unit on the Russian Mir Space Station is the object of much curiosity during preflight preparations in the SPACEHAB Payload Processing Facility. A SPACEHAB Double Module on the Space Shuttle Atlantis will carry the oxygen generator to Mir during STS-84, the sixth Shuttle-Mir docking. The nearly 300-pound generator, manufactured by RSC Energia in Russia, will replace one of two Mir units that have been malfunctioning recently. The generator functions by electrolysis, which separates water into its oxygen and hydrogen components. The hydrogen is vented and the oxygen is used for breathing by the Mir crew. The generator is 4.2 feet in length and 1.4 feet in diameter. STS-84, which is planned to include a Mir crew exchange of astronaut C. Michael Foale for Jerry M. Linenger, is targeted for a May 15 liftoff.

  3. The contribution of cluster and discriminant analysis to the classification of complex aquifer systems.

    PubMed

    Panagopoulos, G P; Angelopoulou, D; Tzirtzilakis, E E; Giannoulopoulos, P

    2016-10-01

    This paper presents an innovated method for the discrimination of groundwater samples in common groups representing the hydrogeological units from where they have been pumped. This method proved very efficient even in areas with complex hydrogeological regimes. The proposed method requires chemical analyses of water samples only for major ions, meaning that it is applicable to most of cases worldwide. Another benefit of the method is that it gives a further insight of the aquifer hydrogeochemistry as it provides the ions that are responsible for the discrimination of the group. The procedure begins with cluster analysis of the dataset in order to classify the samples in the corresponding hydrogeological unit. The feasibility of the method is proven from the fact that the samples of volcanic origin were separated into two different clusters, namely the lava units and the pyroclastic-ignimbritic aquifer. The second step is the discriminant analysis of the data which provides the functions that distinguish the groups from each other and the most significant variables that define the hydrochemical composition of the aquifer. The whole procedure was highly successful as the 94.7 % of the samples were classified to the correct aquifer system. Finally, the resulted functions can be safely used to categorize samples of either unknown or doubtful origin improving thus the quality and the size of existing hydrochemical databases.

  4. Split WHO in two: strengthening political decision-making and securing independent scientific advice.

    PubMed

    Hoffman, Steven J; Røttingen, John-Arne

    2014-02-01

    The World Health Organization (WHO) has never fulfilled its original mission of simultaneously serving as the world's pre-eminent public health authority and intergovernmental platform for global health negotiations. While WHO's secretariat works hard to fulfill both functions, it is undermined by an institutional design that mixes technical and political mandates. This forces staff to walk uncomfortably along many fine lines: advising but never directing; guiding but never governing; leading but never advocating; evaluating but never judging. The result is mediocrity on both fronts. Instead, WHO should be split in two, separating its technical and political stewardship functions into separate entities, with collaboration in areas of overlap. The Executive Board and secretariat would be bifurcated, with technical units reporting to a Technical Board and political units reporting to a Political Board. Both boards would report to the World Health Assembly where all member states would continue to provide ultimate oversight. Such bold changes can be implemented either by revising WHO's constitution or through simpler mechanisms. Either way, structural governance reforms would need to be accompanied by complementary changes in culture that support strengthened political decision-making and scientific independence. States' inability to act on WHO's institutional design challenges will only lead them and non-state actors to continue bypassing the organization through the creation of new entities as they have done over the last 15 years. The key will be to mobilize those advocates and decision-makers who have the audacity to demand more from WHO and convince member states to elevate their ambitions in current WHO reform efforts. Continued progress in global health depends on it. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  5. Interspecific variation in the tetradactyl manus of modern tapirs (Perissodactyla: Tapirus) exposed using geometric morphometrics.

    PubMed

    MacLaren, Jamie A; Nauwelaerts, Sandra

    2017-11-01

    The distal forelimb (autopodium) of quadrupedal mammals is a key morphological unit involved in locomotion, body support, and interaction with the substrate. The manus of the tapir (Perissodactyla: Tapirus) is unique within modern perissodactyls, as it retains the plesiomorphic tetradactyl (four-toed) condition also exhibited by basal equids and rhinoceroses. Tapirs are known to exhibit anatomical mesaxonic symmetry in the manus, although interspecific differences and biomechanical mesaxony have yet to be rigorously tested. Here, we investigate variation in the manus morphology of four modern tapir species (Tapirus indicus, Tapirus bairdii, Tapirus pinchaque, and Tapirus terrestris) using a geometric morphometric approach. Autopodial bones were laser scanned to capture surface shape and morphology was quantified using 3D-landmark analysis. Landmarks were aligned using Generalised Procrustes Analysis, with discriminant function and partial least square analyses performed on aligned coordinate data to identify features that significantly separate tapir species. Overall, our results support the previously held hypothesis that T. indicus is morphologically separate from neotropical tapirs; however, previous conclusions regarding function from morphological differences are shown to require reassessment. We find evidence indicating that T. bairdii exhibits reduced reliance on the lateral fifth digit compared to other tapirs. Morphometric assessment of the metacarpophalangeal joint and the morphology of the distal facets of the lunate lend evidence toward high loading on the lateral digits of both the large T. indicus (large body mass) and the small, long limbed T. pinchaque (ground impact). Our results support other recent studies on T. pinchaque, suggesting subtle but important adaptations to a compliant but inclined habitat. In conclusion, we demonstrate further evidence that the modern tapir forelimb is a variable locomotor unit with a range of interspecific features tailored to habitual and biomechanical needs of each species. © 2017 Wiley Periodicals, Inc.

  6. A meta-GGA level screened range-separated hybrid functional by employing short range Hartree-Fock with a long range semilocal functional.

    PubMed

    Jana, Subrata; Samal, Prasanjit

    2018-03-28

    The range-separated hybrid density functionals are very successful in describing a wide range of molecular and solid-state properties accurately. In principle, such functionals are designed from spherically averaged or system averaged as well as reverse engineered exchange holes. In the present attempt, the screened range-separated hybrid functional scheme has been applied to the meta-GGA rung by using the density matrix expansion based semilocal exchange hole (or functional). The hybrid functional proposed here utilizes the spherically averaged density matrix expansion based exchange hole in the range separation scheme. For slowly varying density correction the range separation scheme is employed only through the local density approximation based exchange hole coupled with the corresponding fourth order gradient approximate Tao-Mo enhancement factor. The comprehensive testing and performance of the newly constructed functional indicates its applicability in describing several molecular properties. The most appealing feature of this present screened hybrid functional is that it will be practically very useful in describing solid-state properties at the meta-GGA level.

  7. Fraction-storage unit for drug-identification system

    NASA Technical Reports Server (NTRS)

    Campen, C. F.; Stuart, J. L.

    1976-01-01

    Device, connecting outputs of all gas chromatographs to single, relatively inexpensive IR spectrometer, reduces costs of system. Storage unit provides buffer storage of samples until infrared spectrometer is ready to accept them. Storage unit can be used to separate overlapping peaks.

  8. Bipartite units of nonlocality

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forster, Manuel; Wolf, Stefan

    Imagine a task in which a group of separated players aim to simulate a statistic that violates a Bell inequality. Given measurement choices the players shall announce an output based solely on the results of local operations--which they can discuss before the separation--on shared random data and shared copies of a so-called unit correlation. In the first part of this paper we show that in such a setting the simulation of any bipartite correlation, not containing the possibility of signaling, can be made arbitrarily accurate by increasing the number of shared Popescu-Rohrlich (PR) boxes. This establishes the PR box asmore » a simple asymptotic unit of bipartite nonlocality. In the second part we study whether this property extends to the multipartite case. More generally, we ask if it is possible for separated players to asymptotically reproduce any nonsignaling statistic by local operations on bipartite unit correlations. We find that nonadaptive strategies are limited by a constant accuracy and that arbitrary strategies on n resource correlations make a mistake with a probability greater or equal to c/n, for some constant c.« less

  9. Reproducibility, temporal stability, and functional correlation of diffusion MR measurements within the spinal cord in patients with asymptomatic cervical stenosis or cervical myelopathy.

    PubMed

    Ellingson, Benjamin M; Salamon, Noriko; Woodworth, Davis C; Yokota, Hajime; Holly, Langston T

    2018-05-01

    OBJECTIVE The purpose of this study was to quantify the reproducibility, temporal stability, and functional correlation of diffusion MR characteristics in the spinal cord in patients with cervical stenosis with or without myelopathy. The association between longitudinal diffusion tensor imaging (DTI) measurements and serial neurological function assessment was explored at both the group and individual level. METHODS Sixty-six nonoperatively treated patients with cervical stenosis were prospectively followed (3 months to > 5 years) using synchronous serial MRI and functional outcome assessment. A total of 183 separate MRI examinations were performed, separated by at least 3 months, and each patient had a minimum of 2 MRI scans (range 2-5 scans). Anatomical and DTI measurements were performed within the spinal cord at the C1-2 region as well as at the area of highest compression. Coefficients of variance (COVs) were compared across measurements in both reference tissue and areas of compression for anatomical measurements, fractional anisotropy (FA), and mean diffusivity (MD). The correlation between diffusion MR measures at the site of compression and evaluations of neurological function assessed using the modified Japanese Orthopaedic Association (mJOA) scale at multiple time points was evaluated. RESULTS The COVs for anatomical measurements (Torg ratio and canal diameter) were between 7% and 10%. The median COV for FA measurements at the site of compression was 9%, and for reference tissue at C1-2 it was 6%. The median COV for MD at the site of compression was approximately 12%, and for reference tissue at C1-2 it was 10%. The FA and MD measurements of C1-2 averaged 0.61 and 0.91 μm 2 /msec, respectively, whereas the FA and MD measurements at the site of compression averaged 0.51 and 1.26 μm 2 /msec, respectively. Both FA (slope = 0.037; R 2 = 0.3281, p < 0.0001) and MD (slope = -0.074; R 2 = 0.1101, p = 0.0084) were significantly correlated with the mJOA score. The FA decreased by approximately 0.032 units per mJOA unit decrease (R 2 = 0.2037, p < 0.0001), whereas the MD was increased by approximately 0.084 μm 2 /msec for every mJOA unit decrease (R 2 = 0.1016, p < 0.0001). CONCLUSIONS Quantitative DTI measurements of the spinal cord in patients with cervical stenosis with or without myelopathy have a median COV of 5%-10%, similar to anatomical measurements. The reproducibility of these measurements and significant correlation with functional outcome status suggest a potential role in the evaluation and longitudinal surveillance of nonoperatively treated patients. With respect to the specific DTI measurements, FA within the spinal cord appears slightly more sensitive to neurological function and more stable than measures of MD. Therefore, DTI of the spinal cord may be a clinically feasible imaging technique for longitudinally monitoring patients with cervical spondylotic myelopathy.

  10. Aggregation in complex triacylglycerol oils: coarse-grained models, nanophase separation, and predicted x-ray intensities

    NASA Astrophysics Data System (ADS)

    Quinn, Bonnie; Peyronel, Fernanda; Gordon, Tyler; Marangoni, Alejandro; Hanna, Charles B.; Pink, David A.

    2014-11-01

    Triacylglycerols (TAGs) are biologically important molecules which form crystalline nanoplatelets (CNPs) and, ultimately, fat crystal networks in edible oils. Characterizing the self-assembled hierarchies of these networks is important to understanding their functionality and oil binding capacity. We have modelled CNPs in multicomponent oils and studied their aggregation. The oil comprises (a) a liquid componentt, and (b) components which phase separately on a nano-scale (nano-phase separation) to coat the surfaces of the CNPs impenetrably, either isotropically or anisotropically, with either liquid-like coatings or crystallites, forming a coating of thickness Δ. We modelled three cases: (i) liquid-liquid nano-phase separation, (ii) solid-liquid nano-phase separation, with CNPs coated isotropically, and (iii) CNPs coated anisotropically. The models were applied to mixes of tristearin and triolein with fully hydrogenated canola oil, shea butter with high oleic sunflower oil, and cotton seed oil. We performed Monte Carlo simulations, computed structure functions and concluded: (1) three regimes arose: (a) thin coating regime, Δ \\lt 0.0701 u (b) transition regime, 0.0701 u≤slant Δ ≤slant 0.0916 u and (c) thick coating regime, Δ \\gt 0.0916 u . (arbitrary units, u) (2) The thin coating regime exhibits 1D TAGwoods, which aggregate, via DLCA/RLCA, into fractal structures which are uniformly distributed in space. (3) In the thick coating regime, for an isotropic coating, TAGwoods are not formed and coated CNPs will not aggregate but will be uniformly distributed in space. For anisotropic coating, TAGwoods can be formed and might form 1D strings but will not form DLCA/RLCA clusters. (4) The regimes are, approximately: thin coating, 0\\lt Δ \\lt 7.0 \\text{nm} transition regime, 7.0\\ltΔ \\lt 9.2 \\text{nm} and thick coating, Δ \\gt 9.2 \\text{nm} (5) The minimum minority TAG concentration required to undergo nano-phase separation is, approximately, 0.29% (thin coatings) and 0.94% (thick coatings). Minority components can have substantial effects upon aggregation for concentrations less than 1%.

  11. Development of a new photocatalytic oxidation air filter for aircraft cabin.

    PubMed

    Ginestet, A; Pugnet, D; Rowley, J; Bull, K; Yeomans, H

    2005-10-01

    A new photocatalytic oxidation air filter (PCO unit) has been designed for aircraft cabin applications. The PCO unit is designed as a regenerable VOC removal system in order to improve the quality of the recirculated air entering the aircraft cabin. The PCO was designed to be a modular unit, with four UV lamps sandwiched between two interchangeable titanium dioxide coated panels. Performances of the PCO unit has been measured in a single pass mode test rig in order to show the ability of the unit to decrease the amount of VOCs (toluene, ethanol, and acetone) entering it (VOCs are fed separately), and in a multipass mode test rig in order to measure the ability of the unit to clean the air of an experimental room polluted with the same VOCs (fed separately). Triangular cell panels have been chosen instead of the wire mesh panels because they have higher efficiency. The efficiency of the PCO unit depends on the type of VOCs that challenges it, toluene being the most difficult one to oxidise. The efficiency of the PCO unit decreases when the air flow rate increases. The multipass mode test results show that the VOCs are oxidized but additional testing time would be necessary in order to show if they can be fully oxidized. The intermediate reaction products are mainly acetaldehyde and formaldehyde whose amount depends on the challenge VOC. The intermediate reaction products are also oxidized and additional testing time would be necessary in order to show if they can be fully oxidized. The development of this new photocatalytic air filter is still going on. The VOC/odor removing adsorbers are available for only a small proportion of aircraft currently in service. The photocatalytic oxidation (PCO) technique has appeared to be a promising solution to odors problems met in aircraft. This article reports the test results of a new photocatalytic oxidation air filter (PCO unit) designed for aircraft cabin applications. The overall efficiency of the PCO unit is function of the compound (toluene, ethanol, and acetone) that challenges the unit and toluene appears to be the most difficult compound to oxidize. Test results have shown the influence of the design of the PCO unit, the air flow rate and the type of UV on the efficiency of the PCO unit. The results obtained in this study represent a first attempt on the way to design a filter for VOC removal in cabin aircraft applications. The PCO technique used by the tested prototype unit is able to partially oxidized the challenge VOCs but one has to be aware that some harmful intermediate reaction products (mainly formaldehyde and acetaldehyde) are produced during the oxidation process before being partially oxidized too.

  12. Dynamics of active sites in biological macromolecules using a Green-function approach: An application to heme vibrational dynamics in myoglobin

    NASA Astrophysics Data System (ADS)

    Rai, Brajesh; Prohofsky, Earl

    2003-03-01

    Dynamics of functionally active regions of biological macromolecules can be studied using a Green-function technique. This approach uses the fact that in most cases one has a good set of force constants for active sites, and rather poorly defined force field parameters for other regions of the macromolecule. The Green-function method is applied to study the iron vibrational modes of the heme active site in myoglobin. In this approach, the heme active site is viewed as a system interacting with surrounding globin, which acts as an excitation bath. The normal modes of heme and globin are separately calculated using the best available force fields for the two entities. The iron vibrational spectrum of myoglobin is then obtained using the solutions of the heme and globin, and by considering physically meaningful interactions between the two units. The refinement of the Green-function calculations to the experimental data from an x-ray synchrotron-based Nuclear Resonance Vibrational Spectroscopy provides important insights into the character of iron normal modes of myoglobin.

  13. 21 CFR 13.15 - Separation of functions; ex parte communications; administrative support.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Separation of functions; ex parte communications... HUMAN SERVICES GENERAL PUBLIC HEARING BEFORE A PUBLIC BOARD OF INQUIRY General Provisions § 13.15 Separation of functions; ex parte communications; administrative support. (a) The proceeding of a Board are...

  14. 21 CFR 10.55 - Separation of functions; ex parte communications.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... concerning the matter in the hearing. All communications are to be public communications, as witness or... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Separation of functions; ex parte communications... Separation of functions; ex parte communications. (a) This section applies to any matter subject by statute...

  15. 21 CFR 10.55 - Separation of functions; ex parte communications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... concerning the matter in the hearing. All communications are to be public communications, as witness or... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Separation of functions; ex parte communications... Separation of functions; ex parte communications. (a) This section applies to any matter subject by statute...

  16. 21 CFR 10.55 - Separation of functions; ex parte communications.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... concerning the matter in the hearing. All communications are to be public communications, as witness or... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Separation of functions; ex parte communications... Separation of functions; ex parte communications. (a) This section applies to any matter subject by statute...

  17. 21 CFR 10.55 - Separation of functions; ex parte communications.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... concerning the matter in the hearing. All communications are to be public communications, as witness or... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Separation of functions; ex parte communications... Separation of functions; ex parte communications. (a) This section applies to any matter subject by statute...

  18. 21 CFR 10.55 - Separation of functions; ex parte communications.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... concerning the matter in the hearing. All communications are to be public communications, as witness or... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Separation of functions; ex parte communications... Separation of functions; ex parte communications. (a) This section applies to any matter subject by statute...

  19. 45 CFR 302.20 - Separation of cash handling and accounting functions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Separation of cash handling and accounting... accounting functions. The State plan shall provide that the following requirements and criteria to separate the cash handling and accounting functions are in effect. (a) IV-D responsibility. The IV-D agency...

  20. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this section...

  1. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this section...

  2. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this section...

  3. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this section...

  4. Solid Waste/Energy Curriculum.

    ERIC Educational Resources Information Center

    Vivan, V. Eugene; And Others

    Provided are solid waste/energy curriculum materials for grades K-2, 3-4, 5-6, 7-9, and 10-12. Separate folders containing units of study (focusing on trash, litter, and recycling) are provided for kindergarten (four units), grade 1 (two units), and grade 2 (two units). Folders contain teachers' directions and activity cards which include picture…

  5. 8 CFR 1215.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) The term alien means any person who is not a citizen or national of the United States. (b) The term... Hawaii. (g) The term geographical part of the United States means: (1) The continental United States, (2... place, or (2) from one geographical part of the United States for a separate geographical part of the...

  6. 8 CFR 1215.1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) The term alien means any person who is not a citizen or national of the United States. (b) The term... Hawaii. (g) The term geographical part of the United States means: (1) The continental United States, (2... place, or (2) from one geographical part of the United States for a separate geographical part of the...

  7. Space Station Water Processor Mostly Liquid Separator (MLS)

    NASA Technical Reports Server (NTRS)

    Lanzarone, Anthony

    1995-01-01

    This report presents the results of the development testing conducted under this contract to the Space Station Water Processor (WP) Mostly Liquid Separator (MLS). The MLS units built and modified during this testing demonstrated acceptable air/water separation results in a variety of water conditions with inlet flow rates ranging from 60 - 960 LB/hr.

  8. Supra-domains: evolutionary units larger than single protein domains.

    PubMed

    Vogel, Christine; Berzuini, Carlo; Bashton, Matthew; Gough, Julian; Teichmann, Sarah A

    2004-02-20

    Domains are the evolutionary units that comprise proteins, and most proteins are built from more than one domain. Domains can be shuffled by recombination to create proteins with new arrangements of domains. Using structural domain assignments, we examined the combinations of domains in the proteins of 131 completely sequenced organisms. We found two-domain and three-domain combinations that recur in different protein contexts with different partner domains. The domains within these combinations have a particular functional and spatial relationship. These units are larger than individual domains and we term them "supra-domains". Amongst the supra-domains, we identified some 1400 (1203 two-domain and 166 three-domain) combinations that are statistically significantly over-represented relative to the occurrence and versatility of the individual component domains. Over one-third of all structurally assigned multi-domain proteins contain these over-represented supra-domains. This means that investigation of the structural and functional relationships of the domains forming these popular combinations would be particularly useful for an understanding of multi-domain protein function and evolution as well as for genome annotation. These and other supra-domains were analysed for their versatility, duplication, their distribution across the three kingdoms of life and their functional classes. By examining the three-dimensional structures of several examples of supra-domains in different biological processes, we identify two basic types of spatial relationships between the component domains: the combined function of the two domains is such that either the geometry of the two domains is crucial and there is a tight constraint on the interface, or the precise orientation of the domains is less important and they are spatially separate. Frequently, the role of the supra-domain becomes clear only once the three-dimensional structure is known. Since this is the case for only a quarter of the supra-domains, we provide a list of the most important unknown supra-domains as potential targets for structural genomics projects.

  9. Examining the Hospital Elder Life Program in a rehabilitation setting: a pilot feasibility study.

    PubMed

    Huson, Kelsey; Stolee, Paul; Pearce, Nancy; Bradfield, Corrie; Heckman, George A

    2016-07-18

    The Hospital Elder Life Program (HELP) has been shown to effectively prevent delirium and functional decline in older patients in acute care, but has not been examined in a rehabilitation setting. This pilot study examined potential successes and implementation factors of the HELP in a post-acute rehabilitation hospital setting. A mixed methods (quantitative and qualitative) evaluation, incorporating a repeated measures design, was used. A total of 100 patients were enrolled; 58 on the pilot intervention unit and 42 on a usual care unit. Group comparisons were made using change scores (pre-post intervention) on outcome measures between pilot unit patients and usual care patients (separate analyses compared usual care patients with pilot unit patients who did or did not receive the HELP). Qualitative data were collected using focus group and individual interviews, and analyzed using emergent coding procedures. Delirium prevalence reduced from 10.9 % (n = 6) to 2.5 % (n = 1) in the intervention group, while remaining the same in the usual care group (2.5 % at both measurement points). Those who received the HELP showed greater improvement on cognitive and functional outcomes, particularly short-term memory and recall, and a shorter average length of stay than patients who did not. Participant groups discussed perceived barriers, benefits, and recommendations for further implementation of the HELP in a rehabilitation setting. This study adds to the limited research on delirium and the effectiveness of the HELP in post-acute rehabilitation settings. The HELP was found to be feasible and have potential benefits for reduced delirium and improved outcomes among rehabilitation patients.

  10. Caustic Recycling Pilot Unit to Separate Sodium from LLW at Hanford Site - 12279

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pendleton, Justin; Bhavaraju, Sai; Priday, George

    As part of the Department of Energy (DOE) sponsored Advanced Remediation Technologies initiative, a scheme was developed to combine Continuous Sludge Leaching (CSL), Near-Tank Cesium Removal (NTCR), and Caustic Recycling Unit (CRU) using Ceramatec technology, into a single system known as the Pilot Near-Tank Treatment System (PNTTS). The Cesium (Cs) decontaminated effluent from the NTCR process will be sent to the caustic recycle process for recovery of the caustic which will be reused in another cycle of caustic leaching in the CSL process. Such an integrated mobile technology demonstration will give DOE the option to insert this process for sodiummore » management at various sites in Hanford, and will minimize the addition of further sodium into the waste tanks. This allows for recycling of the caustic used to remove aluminum during sludge washing as a pretreatment step in the vitrification of radioactive waste which will decrease the Low Level Waste (LLW) volume by as much as 39%. The CRU pilot process was designed to recycle sodium in the form of pure sodium hydroxide. The basis for the design of the 1/4 scale pilot caustic recycling unit was to demonstrate the efficient operation of a larger scale system to recycle caustic from the NTCR effluent stream from the Parsons process. The CRU was designed to process 0.28 liter/minute of NTCR effluent, and generate 10 M concentration of 'usable' sodium hydroxide. The proposed process operates at 40 deg. C to provide additional aluminum solubility and then recover the sodium hydroxide to the point where the aluminum is saturated at 40 deg. C. A system was developed to safely separate and vent the gases generated during operation of the CRU with the production of 10 M sodium hydroxide. Caustic was produced at a rate between 1.9 to 9.3 kg/hr. The CRU was located inside an ISO container to allow for moving of the unit close to tank locations to process the LLW stream. Actual tests were conducted with the NTCR effluent simulant from the Parsons process in the CRU. The modular CRU is easily scalable as a standalone system for caustic recycling, or for NTTS integration or for use as an In-Tank Treatment System to process sodium bearing waste to meet LLW processing needs at the Hanford site. The standalone pilot operation of the CRU to recycle sodium from NTCR effluent places the technology demonstration at TRL level 6. Multiple operations were performed with the CRU to process up to 500 gallons of the NTCR effluent and demonstrate an efficient separation of up to 70 % of the sodium without solids precipitation while producing 10 M caustic. Batch mode operation was conducted to study the effects of chemistry variation, establish the processing rate, and optimize the process operating conditions to recycle caustic from the NTCR effluent. The performance of the CRU was monitored by tracking the density parameter to control the concentration of caustic produced. Different levels of sodium were separated in tests from the effluent at a fixed operating current density and temperature. The voltage of the modules remained stable during the unit operation which demonstrated steady operation to separate sodium from the NTCR effluent. The sodium transfer current efficiency was measured in testing based on the concentration of caustic produced. Measurements showed a current efficiency of 99.8% for sodium transfer from the NTCR effluent to make sodium hydroxide. The sodium and hydroxide contents of the anolyte (NTCR feed) and catholyte (caustic product) were measured before and after each batch test. In two separate batch tests, samples were taken at different levels of sodium separation and analyzed to determine the stability of the NTCR effluent after sodium separation. The stability characteristics and changes in physical and chemical properties of the NTCR effluent chemistry after separation of sodium hydroxide as a function of storage time were evaluated. Parameters such as level of precipitated alumina, total alkalinity, analysis of Al, Na, K, Cs, Fe, OH, nitrate, nitrite, total dissolved and undissolved solids, viscosity, density, and other parameters of the NTCR effluent were measured. Changes in rheology and properties of NTCR stream to support downstream handling of the effluent after sodium separation was the basis for the analysis. The results show that the NTCR effluent is stable without the precipitation of aluminum hydroxide after 70% of the sodium was separated from the effluent. (authors)« less

  11. Maternal depression in the United States: nationally representative rates and risks.

    PubMed

    Ertel, Karen A; Rich-Edwards, Janet W; Koenen, Karestan C

    2011-11-01

    To examine the public health burden of major depressive disorder (MDD) among mothers: its prevalence and sociodemographic patterns; associated functioning, comorbidities, and adversities; and racial/ethnic disparities. This was a cross-sectional analysis of 8916 mothers in the National Epidemiologic Survey of Alcohol and Related Conditions, a nationally representative survey of the civilian U.S. population in 2001?2002. Past-year MDD was assessed with a structured interview protocol. Ten percent of mothers experienced depression in the past year. White and Native American women, those with low education or income, and those not married had high rates of depression. Depression was not strongly patterned by number of or age of children. Depressed mothers experienced more adversities (poverty, separation or divorce, unemployment, financial difficulties) and had worse functioning. Half of depressed mothers received services for their depression. Black and Hispanic depressed mothers were more likely to experience multiple adversities and less likely to receive services than white depressed mothers. Maternal depression is a major public health problem in the United States, with an estimated 1 in 10 children experiencing a depressed mother in any given year. Professionals who work with mothers and children should be aware of its prevalence and its detrimental effects.

  12. Self-Assembled Polystyrene Beads for Templated Covalent Functionalization of Graphitic Substrates Using Diazonium Chemistry.

    PubMed

    Van Gorp, Hans; Walke, Peter; Bragança, Ana M; Greenwood, John; Ivasenko, Oleksandr; Hirsch, Brandon E; De Feyter, Steven

    2018-04-11

    A network of self-assembled polystyrene beads was employed as a lithographic mask during covalent functionalization reactions on graphitic surfaces to create nanocorrals for confined molecular self-assembly studies. The beads were initially assembled into hexagonal arrays at the air-liquid interface and then transferred to the substrate surface. Subsequent electrochemical grafting reactions involving aryl diazonium molecules created covalently bound molecular units that were localized in the void space between the nanospheres. Removal of the bead template exposed hexagonally arranged circular nanocorrals separated by regions of chemisorbed molecules. Small molecule self-assembly was then investigated inside the resultant nanocorrals using scanning tunneling microscopy to highlight localized confinement effects. Overall, this work illustrates the utility of self-assembly principles to transcend length scale gaps in the development of hierarchically patterned molecular materials.

  13. Geometric multiaxial representation of N -qubit mixed symmetric separable states

    NASA Astrophysics Data System (ADS)

    SP, Suma; Sirsi, Swarnamala; Hegde, Subramanya; Bharath, Karthik

    2017-08-01

    The study of N -qubit mixed symmetric separable states is a longstanding challenging problem as no unique separability criterion exists. In this regard, we take up the N -qubit mixed symmetric separable states for a detailed study as these states are of experimental importance and offer an elegant mathematical analysis since the dimension of the Hilbert space is reduced from 2N to N +1 . Since there exists a one-to-one correspondence between the spin-j system and an N -qubit symmetric state, we employ Fano statistical tensor parameters for the parametrization of the spin-density matrix. Further, we use a geometric multiaxial representation (MAR) of the density matrix to characterize the mixed symmetric separable states. Since the separability problem is NP-hard, we choose to study it in the continuum limit where mixed symmetric separable states are characterized by the P -distribution function λ (θ ,ϕ ) . We show that the N -qubit mixed symmetric separable states can be visualized as a uniaxial system if the distribution function is independent of θ and ϕ . We further choose a distribution function to be the most general positive function on a sphere and observe that the statistical tensor parameters characterizing the N -qubit symmetric system are the expansion coefficients of the distribution function. As an example for the discrete case, we investigate the MAR of a uniformly weighted two-qubit mixed symmetric separable state. We also observe that there exists a correspondence between the separability and classicality of states.

  14. 40 CFR 60.1055 - What is a materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Waste Combustion Units for Which Construction is Commenced After August 30, 1999 or for Which... separating certain components of municipal solid waste for a given service area prior to waste combustion and...

  15. 40 CFR 60.1055 - What is a materials separation plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Waste Combustion Units for Which Construction is Commenced After August 30, 1999 or for Which... separating certain components of municipal solid waste for a given service area prior to waste combustion and...

  16. Non-urban mobile radio market demand forecast

    NASA Technical Reports Server (NTRS)

    Castruccio, P. A.; Cooper, J.

    1982-01-01

    A national nonmetropolitan land mobile traffic model for 1990-2000 addresses user classes, density classes, traffic mix statistics, distance distribution, geographic distribution, price elasticity, and service quality elasticity. Traffic demands for business, special industrial, and police were determined on the basis of surveys in 73 randomly selected nonurban counties. The selected services represent 69% of total demand. The results were extrapolated to all services in the non-SMSA areas of the contiguous United States. Radiotelephone services were considered separately. Total non-SMSA mobile radio demand (one way) estimates are given. General functional requirements include: hand portability, privacy, reduction of blind spots, two way data transmission, position location, slow scan imagery.

  17. Analysis of thermodynamics of two-fuel power unit integrated with a carbon dioxide separation plant

    NASA Astrophysics Data System (ADS)

    Kotowicz, Janusz; Bartela, Łukasz; Mikosz, Dorota

    2014-12-01

    The article presents the results of thermodynamic analysis of the supercritical coal-fired power plant with gross electrical output of 900 MW and a pulverized coal boiler. This unit is integrated with the absorption-based CO2 separation installation. The heat required for carrying out the desorption process, is supplied by the system with the gas turbine. Analyses were performed for two variants of the system. In the first case, in addition to the gas turbine there is an evaporator powered by exhaust gases from the gas turbine expander. The second expanded variant assumes the application of gas turbine combined cycle with heat recovery steam generator and backpressure steam turbine. The way of determining the efficiency of electricity generation and other defined indicators to assess the energy performance of the test block was showed. The size of the gas turbine system was chosen because of the need for heat for the desorption unit, taking the value of the heat demand 4 MJ/kg CO2. The analysis results obtained for the both variants of the installation with integrated CO2 separation plant were compared with the results of the analysis of the block where the separation is not conducted.

  18. Urethral pressure reflectometry during intra-abdominal pressure increase-an improved technique to characterize the urethral closure function in continent and stress urinary incontinent women.

    PubMed

    Saaby, Marie-Louise; Klarskov, Niels; Lose, Gunnar

    2013-11-01

    to assess the urethral closure function by urethral pressure reflectometry (UPR) during intra-abdominal pressure-increase in SUI and continent women. Twenty-five urodynamically proven SUI women and eight continent volunteer women were assessed by ICIQ-SF, pad-weighing test, incontinence diary, and UPR. UPR was conducted during resting and increased intra-abdominal pressure (P(Abd)) by straining. Related values of P(Abd) and urethral opening pressure (P(o)) were plotted into an abdomino-urethral pressuregram. Linear regression of the values was conducted, and the slope of the line ("APIR") and the intercept with the y-axis found. By the equation of the line, Po was calculated for various values of P(Abd), for example, 50 cm H2O (P(o-Abd 50)). The resting P(o) (P(o-rest)) and APIR, respectively, significantly differed in SUI and continent women but could not separate the two groups. The urethral closure equation (UCE) based on P(o-rest) and APIR provided a more detailed characterization of a woman's closure function based on the permanent closure forces (primarily generated by the urethral sphincteric unit) and the adjunctive closure forces (primarily generated by the support system). P(o-Abd 50) and UCE, respectively, which express the combined permanent and adjunctive closure forces and estimate the efficiency of the closure function, separated SUI and continent women and were highly significantly negatively correlated with ICIQ-SF, pad test, and the number of incontinence episodes. New parameters for characterization of the urethral closure function and possible dysfunctions and its efficiency were provided. P(o-Abd 50) and UCE may be used as diagnostic tests and severity measures. © 2013 Wiley Periodicals, Inc.

  19. ENVIRONMENTAL TECHNOLOGY VERIFICATION: JOINT (NSF-EPA) VERIFICATION STATEMENT AND REPORT: BROME AGRI SALES, LTD., MAXIMIZER SEPARATOR, MODEL MAX 1016 - 03/01/WQPC-SWP

    EPA Science Inventory

    Verification testing of the Brome Agri Sales Ltd. Maximizer Separator, Model MAX 1016 (Maximizer) was conducted at the Lake Wheeler Road Field Laboratory Swine Educational Unit in Raleigh, North Carolina. The Maximizer is an inclined screen solids separator that can be used to s...

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: STORMWATER SOURCE AREA TREATMENT DEVICE — BAYSAVER TECHNOLOGIES, INC. BAYSAVER SEPARATION SYSTEM, MODEL 10K

    EPA Science Inventory

    Verification testing of the BaySaver Separation System, Model 10K was conducted on a 10 acre drainage basin near downtown Griffin, Georgia. The system consists of two water tight pre-cast concrete manholes and a high-density polyethylene BaySaver Separator Unit. The BaySaver Mod...

  1. 75 FR 5788 - Notice of Availability of Draft National Pollutant Discharge Elimination System (NPDES) General...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... Discharge Elimination System (NPDES) General Permits for Small Municipal Separate Storm Sewer Systems (MS4... at 40 CFR 122.26(b)(16) define a small municipal separate storm sewer system as ``* * * all separate storm sewers that are: (1) Owned or operated by the United States, a State, city, town, borough, county...

  2. Basis convergence of range-separated density-functional theory.

    PubMed

    Franck, Odile; Mussard, Bastien; Luppi, Eleonora; Toulouse, Julien

    2015-02-21

    Range-separated density-functional theory (DFT) is an alternative approach to Kohn-Sham density-functional theory. The strategy of range-separated density-functional theory consists in separating the Coulomb electron-electron interaction into long-range and short-range components and treating the long-range part by an explicit many-body wave-function method and the short-range part by a density-functional approximation. Among the advantages of using many-body methods for the long-range part of the electron-electron interaction is that they are much less sensitive to the one-electron atomic basis compared to the case of the standard Coulomb interaction. Here, we provide a detailed study of the basis convergence of range-separated density-functional theory. We study the convergence of the partial-wave expansion of the long-range wave function near the electron-electron coalescence. We show that the rate of convergence is exponential with respect to the maximal angular momentum L for the long-range wave function, whereas it is polynomial for the case of the Coulomb interaction. We also study the convergence of the long-range second-order Møller-Plesset correlation energy of four systems (He, Ne, N2, and H2O) with cardinal number X of the Dunning basis sets cc - p(C)V XZ and find that the error in the correlation energy is best fitted by an exponential in X. This leads us to propose a three-point complete-basis-set extrapolation scheme for range-separated density-functional theory based on an exponential formula.

  3. Deep Ensemble Learning for Monaural Speech Separation

    DTIC Science & Technology

    2015-02-01

    cse.ohio- state.edu). typically predict the ideal binary mask (IBM) or ideal ratio mask ( IRM ). For the IBM [21], a T-F unit is assigned 1, if the signal...dominance. For the IRM [17], a T- F unit is assigned some ratio of target energy and mixture energy. Kim et al. [15] used Gaussian mixture models (GMM...significantly outperforms earlier separation methods. Subsequently, Wang et al. [23] examined a number of training targets and suggested that the IRM should be

  4. Evaluation of BAUER High Pressure Breathing Air P-2 Purification System

    DTIC Science & Technology

    1991-08-01

    and is a coalescing type separator that removes oil and water vapors suspended in the compressed air . The molecular sieve is made to adsorb oil and...filtering, moisture separation, and prevents compressed air return from the charged air storage flasks to the compressor during unit shutdown. A manual...1111111111111 1111 IE IH fil91i C NAVY EXPERIMENTAL DIVING UNIT REPORT NO. 10-91 EVALUATION OF BAUER HIGH PRESSURE BREATHING AIR P-2 PURIFICATION SYSTEM GEORGE D

  5. Process for removing an organic compound from water

    DOEpatents

    Baker, Richard W.; Kaschemekat, Jurgen; Wijmans, Johannes G.; Kamaruddin, Henky D.

    1993-12-28

    A process for removing organic compounds from water is disclosed. The process involves gas stripping followed by membrane separation treatment of the stripping gas. The stripping step can be carried out using one or multiple gas strippers and using air or any other gas as stripping gas. The membrane separation step can be carried out using a single-stage membrane unit or a multistage unit. Apparatus for carrying out the process is also disclosed. The process is particularly suited for treatment of contaminated groundwater or industrial wastewater.

  6. Space Separatism: Degree of Differentiation

    DTIC Science & Technology

    2014-12-01

    Separate Service” (Norfolk, VA: Joint Forces Staff College, 6 September 2002); MAJ William S. Moncrief , “Building a United States Space Force,” Army Space...unclassified b. ABSTRACT unclassified c . THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 November–December 2014 Air...FY14_Green_Book.pdf. 32. Story, “Separate Space Force,” 2–5. 33. Moncrief , “Building a United States Space Force,” 34–38. 34. DODD 3100.10, Space Policy, 3. 35. Lt

  7. Peak capacity and peak capacity per unit time in capillary and microchip zone electrophoresis.

    PubMed

    Foley, Joe P; Blackney, Donna M; Ennis, Erin J

    2017-11-10

    The origins of the peak capacity concept are described and the important contributions to the development of that concept in chromatography and electrophoresis are reviewed. Whereas numerous quantitative expressions have been reported for one- and two-dimensional separations, most are focused on chromatographic separations and few, if any, quantitative unbiased expressions have been developed for capillary or microchip zone electrophoresis. Making the common assumption that longitudinal diffusion is the predominant source of zone broadening in capillary electrophoresis, analytical expressions for the peak capacity are derived, first in terms of migration time, diffusion coefficient, migration distance, and desired resolution, and then in terms of the remaining underlying fundamental parameters (electric field, electroosmotic and electrophoretic mobilities) that determine the migration time. The latter expressions clearly illustrate the direct square root dependence of peak capacity on electric field and migration distance and the inverse square root dependence on solute diffusion coefficient. Conditions that result in a high peak capacity will result in a low peak capacity per unit time and vice-versa. For a given symmetrical range of relative electrophoretic mobilities for co- and counter-electroosmotic species (cations and anions), the peak capacity increases with the square root of the electric field even as the temporal window narrows considerably, resulting in a significant reduction in analysis time. Over a broad relative electrophoretic mobility interval [-0.9, 0.9], an approximately two-fold greater amount of peak capacity can be generated for counter-electroosmotic species although it takes about five-fold longer to do so, consistent with the well-known bias in migration time and resolving power for co- and counter-electroosmotic species. The optimum lower bound of the relative electrophoretic mobility interval [μ r,Z , μ r,A ] that provides the maximum peak capacity per unit time is a simple function of the upper bound, but its direct application is limited to samples with analytes whose electrophoretic mobilities can be varied independently of electroosmotic flow. For samples containing both co- and counter-electroosmotic ions whose electrophoretic mobilities cannot be easily manipulated, comparable levels of peak capacity and peak capacity per unit time for all ions can be obtained by adjusting the EOF to devote the same amount of time to the separation of each class of ions; this corresponds to μ r,Z =-0.5. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. 14 CFR 25.1331 - Instruments using a power supply.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... or more physically separate units or components connected together (such as a remote indicating gyroscopic direction indicator that includes a magnetic sensing element, a gyroscopic unit, an amplifier and...

  9. 14 CFR 25.1331 - Instruments using a power supply.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... or more physically separate units or components connected together (such as a remote indicating gyroscopic direction indicator that includes a magnetic sensing element, a gyroscopic unit, an amplifier and...

  10. Implementation of European standards of care for cystic fibrosis--control and treatment of infection.

    PubMed

    Elborn, J S; Hodson, M; Bertram, C

    2009-05-01

    Several guidelines on infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable. Adherence to European Consensus Guidelines for CF was studied by sending surveys to named healthcare professionals in 487 European CF centres/units. Qualitative data analysis was performed. A total of 177/547 (32%) surveys were returned. Infection control policies were implemented by most (77%) respondents. Separation of patients with Burkholderia cepacia was more common in adults (95%) than children (9%), and was implemented by 53% of respondents for Pseudomonas aeruginosa. Nebulised colistin plus oral ciprofloxacin was the most common (43%) therapy for P. aeruginosa infection. First infections of P. aeruginosa were usually treated with inhaled tobramycin; 41% of repondents did not intervene until lung function deteriorated. Most exacerbations were treated for less than the recommended period. European Consensus Guidelines are widely adhered to. Areas for improvement include: initiating therapy for exacerbations early, separating infected patients and optimising duration of antibiotic therapy.

  11. Hierarchical CaCO3 chromatography: a stationary phase based on biominerals.

    PubMed

    Sato, Kosuke; Oaki, Yuya; Takahashi, Daisuke; Toshima, Kazunobu; Imai, Hiroaki

    2015-03-23

    In biomineralization, acidic macromolecules play important roles for the growth control of crystals through a specific interaction. Inspired by this interaction, we report on an application of the hierarchical structures in CaCO3 biominerals to a stationary phase of chromatography. The separation and purification of acidic small organic molecules are achieved by thin-layer chromatography and flash chromatography using the powder of biominerals as the stationary phase. The unit nanocrystals and their oriented assembly, the hierarchical structure, are suitable for the adsorption site of the target organic molecules and the flow path of the elution solvents, respectively. The separation mode is ascribed to the specific adsorption of the acidic molecules on the crystal face and the coordination of the functional groups to the calcium ions. The results imply that a new family of stationary phase of chromatography can be developed by the fine tuning of hierarchical structures in CaCO3 materials. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Continuous flow electrophoretic separation of proteins and cells from mammalian tissues

    NASA Technical Reports Server (NTRS)

    Hymer, W. C.; Barlow, Grant H.; Blaisdell, Steven J.; Cleveland, Carolyn; Farrington, Mary Ann; Feldmeier, Mary; Hatfield, J. Michael; Lanham, J. Wayne; Grindeland, Richard; Snyder, Robert S.

    1987-01-01

    This paper describes an apparatus for continuous flow electrophoresis (CFE), designed to separate macromolecules and cells at conditions of microgravity. In this CFE, buffer flows upward in a 120-cm long flow chamber, which is 16-cm wide x 3.0-mm thick in the microgravity version (and 6-cm wide x 1.5-mm thick in the unit-gravity laboratory version). Ovalbumin and rat serum albumin were separated in space (flight STS-4) with the same resolution of the two proteins achieved at 25 percent total w/v concentration that was obtained in the laboratory at 0.2 percent w/v concentration. Rat anterior pituitary cells, cultured human embryonic kidney cells, and canine Langerhans cells were separated into subpopulations (flight STS-8) more effectively than in unit gravity, with comparable resolution having been achieved at 100 times the concentration possible on earth.

  13. Application of independent component analysis for speech-music separation using an efficient score function estimation

    NASA Astrophysics Data System (ADS)

    Pishravian, Arash; Aghabozorgi Sahaf, Masoud Reza

    2012-12-01

    In this paper speech-music separation using Blind Source Separation is discussed. The separating algorithm is based on the mutual information minimization where the natural gradient algorithm is used for minimization. In order to do that, score function estimation from observation signals (combination of speech and music) samples is needed. The accuracy and the speed of the mentioned estimation will affect on the quality of the separated signals and the processing time of the algorithm. The score function estimation in the presented algorithm is based on Gaussian mixture based kernel density estimation method. The experimental results of the presented algorithm on the speech-music separation and comparing to the separating algorithm which is based on the Minimum Mean Square Error estimator, indicate that it can cause better performance and less processing time

  14. Centrifugal microfluidic platforms: advanced unit operations and applications.

    PubMed

    Strohmeier, O; Keller, M; Schwemmer, F; Zehnle, S; Mark, D; von Stetten, F; Zengerle, R; Paust, N

    2015-10-07

    Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic companies either have products on the market or are currently evaluating centrifugal microfluidics for product development. The fields of application are widespread and include clinical chemistry, immunodiagnostics and protein analysis, cell handling, molecular diagnostics, as well as food, water, and soil analysis. Nevertheless, new fluidic functions and applications that expand the possibilities of centrifugal microfluidics are being introduced at a high pace. In this review, we first present an up-to-date comprehensive overview of centrifugal microfluidic unit operations. Then, we introduce the term "process chain" to review how these unit operations can be combined for the automation of laboratory workflows. Such aggregation of basic functionalities enables efficient fluidic design at a higher level of integration. Furthermore, we analyze how novel, ground-breaking unit operations may foster the integration of more complex applications. Among these are the storage of pneumatic energy to realize complex switching sequences or to pump liquids radially inward, as well as the complete pre-storage and release of reagents. In this context, centrifugal microfluidics provides major advantages over other microfluidic actuation principles: the pulse-free inertial liquid propulsion provided by centrifugal microfluidics allows for closed fluidic systems that are free of any interfaces to external pumps. Processed volumes are easily scalable from nanoliters to milliliters. Volume forces can be adjusted by rotation and thus, even for very small volumes, surface forces may easily be overcome in the centrifugal gravity field which enables the efficient separation of nanoliter volumes from channels, chambers or sensor matrixes as well as the removal of any disturbing bubbles. In summary, centrifugal microfluidics takes advantage of a comprehensive set of fluidic unit operations such as liquid transport, metering, mixing and valving. The available unit operations cover the entire range of automated liquid handling requirements and enable efficient miniaturization, parallelization, and integration of assays.

  15. Failure Analysis Results and Corrective Actions Implemented for the Extravehicular Mobility Unit 3011 Water in the Helmet Mishap

    NASA Technical Reports Server (NTRS)

    Steele, John; Metselaar, Carol; Peyton, Barbara; Rector, Tony; Rossato, Robert; Macias, Brian; Weigel, Dana; Holder, Don

    2015-01-01

    Water entered the Extravehicular Mobility Unit (EMU) helmet during extravehicular activity (EVA) no. 23 aboard the International Space Station on July 16, 2013, resulting in the termination of the EVA approximately 1 hour after it began. It was estimated that 1.5 liters of water had migrated up the ventilation loop into the helmet, adversely impacting the astronaut's hearing, vision, and verbal communication. Subsequent on-board testing and ground-based test, tear-down, and evaluation of the affected EMU hardware components determined that the proximate cause of the mishap was blockage of all water separator drum holes with a mixture of silica and silicates. The blockages caused a failure of the water separator degassing function, which resulted in EMU cooling water spilling into the ventilation loop, migrating around the circulating fan, and ultimately pushing into the helmet. The root cause of the failure was determined to be ground-processing shortcomings of the Airlock Cooling Loop Recovery (ALCLR) Ion Filter Beds, which led to various levels of contaminants being introduced into the filters before they left the ground. Those contaminants were thereafter introduced into the EMU hardware on-orbit during ALCLR scrubbing operations. This paper summarizes the failure analysis results along with identified process, hardware, and operational corrective actions that were implemented as a result of findings from this investigation.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaminski, Michael

    The Irreversible Wash Aid Additive process has been under development by the U.S. Environmental Protection Agency (EPA) and Argonne National Laboratory (Argonne). This process for radioactive cesium mitigation consists of a solution to wash down contaminated structures, roadways, and vehicles and a sequestering agent to bind the radionuclides from the wash water and render them environmentally immobile. The purpose of this process is to restore functionality to basic services and immediately reduce the consequences of a radiologically-contaminated urban environment. Research and development have resulted in a down-selection of technologies for integration and demonstration at the pilot-scale level as part ofmore » the Wide Area Recovery and Resiliency Program (WARRP) under the Department of Homeland Security and the Denver Urban Area Security Initiative. As part of developing the methods for performing a pilot-scale demonstration at the WARRP conference in Denver in 2012, Argonne conducted small-scale field experiments at Separmatic Systems. The main purpose of these experiments was to refine the wash water collection and separations systems and demonstrate key unit operations to help in planning for the large scale demonstration in Denver. Since the purpose of these tests was to demonstrate the operations of the system, we used no radioactive materials. After a brief set of experiments with the LAKOS unit to familiarize ourselves with its operation, two experiments were completed on two separate dates with the Separmatic systems.« less

  17. Microgravity Passive Phase Separator

    NASA Technical Reports Server (NTRS)

    Paragano, Matthew; Indoe, William; Darmetko, Jeffrey

    2012-01-01

    A new invention disclosure discusses a structure and process for separating gas from liquids in microgravity. The Microgravity Passive Phase Separator consists of two concentric, pleated, woven stainless- steel screens (25-micrometer nominal pore) with an axial inlet, and an annular outlet between both screens (see figure). Water enters at one end of the center screen at high velocity, eventually passing through the inner screen and out through the annular exit. As gas is introduced into the flow stream, the drag force exerted on the bubble pushes it downstream until flow stagnation or until it reaches an equilibrium point between the surface tension holding bubble to the screen and the drag force. Gas bubbles of a given size will form a front that is moved further down the length of the inner screen with increasing velocity. As more bubbles are added, the front location will remain fixed, but additional bubbles will move to the end of the unit, eventually coming to rest in the large cavity between the unit housing and the outer screen (storage area). Owing to the small size of the pores and the hydrophilic nature of the screen material, gas does not pass through the screen and is retained within the unit for emptying during ground processing. If debris is picked up on the screen, the area closest to the inlet will become clogged, so high-velocity flow will persist farther down the length of the center screen, pushing the bubble front further from the inlet of the inner screen. It is desired to keep the velocity high enough so that, for any bubble size, an area of clean screen exists between the bubbles and the debris. The primary benefits of this innovation are the lack of any need for additional power, strip gas, or location for venting the separated gas. As the unit contains no membrane, the transport fluid will not be lost due to evaporation in the process of gas separation. Separation is performed with relatively low pressure drop based on the large surface area of the separating screen. Additionally, there are no moving parts, and there are no failure modes that involve fluid loss. A patent application has been filed.

  18. Covalently functionalized carbon nanostructures and methods for their separation

    DOEpatents

    Wang, YuHuang; Brozena, Alexandra H; Deng, Shunliu; Zhang, Yin

    2015-03-17

    The present invention is directed to carbon nanostructures, e.g., carbon nanotubes, methods of covalently functionalizing carbon nanostructures, and methods of separating and isolating covalently functionalized carbon. In some embodiments, carbon nanotubes are reacted with alkylating agents to provide water soluble covalently functionalized carbon nanotubes. In other embodiments, carbon nanotubes are reacted with a thermally-responsive agent and exposed to light in order to separate carbon nanotubes of a specific chirality from a mixture of carbon nanotubes.

  19. Gravity's Smoking Gun?

    NASA Astrophysics Data System (ADS)

    Gaztañaga, Enrique; Juszkiewicz, Roman

    2001-09-01

    We present a new constraint on the biased galaxy formation picture. Gravitational instability theory predicts that the two-point mass density correlation function, ξ(r), has an inflection point at the separation r=r0, corresponding to the boundary between the linear and nonlinear regime of clustering, ξ~=1. We show how this feature can be used to constrain the biasing parameter b2≡ξg(r)/ξ(r) on scales r~=r0, where ξg is the galaxy-galaxy correlation function, which is allowed to differ from ξ. We apply our method to real data: the ξg(r), estimated from the Automatic Plate Measuring (APM) galaxy survey. Our results suggest that the APM galaxies trace the mass at separations r>~5 h-1 Mpc, where h is the Hubble constant in units of 100 km s-1 Mpc-1. The present results agree with earlier studies, based on comparing higher order correlations in the APM with weakly nonlinear perturbation theory. Both approaches constrain the b factor to be within 20% of unity. If the existence of the feature that we identified in the APM ξg(r)-the inflection point near ξg=1-is confirmed by more accurate surveys, we may have discovered gravity's smoking gun: the long-awaited ``shoulder'' in ξ, predicted by Gott and Rees 25 years ago.

  20. Energy transfer in light-adapted photosynthetic membranes: from active to saturated photosynthesis.

    PubMed

    Fassioli, Francesca; Olaya-Castro, Alexandra; Scheuring, Simon; Sturgis, James N; Johnson, Neil F

    2009-11-04

    In bacterial photosynthesis light-harvesting complexes, LH2 and LH1 absorb sunlight energy and deliver it to reaction centers (RCs) with extraordinarily high efficiency. Submolecular resolution images have revealed that both the LH2:LH1 ratio, and the architecture of the photosynthetic membrane itself, adapt to light intensity. We investigate the functional implications of structural adaptations in the energy transfer performance in natural in vivo low- and high-light-adapted membrane architectures of Rhodospirillum photometricum. A model is presented to describe excitation migration across the full range of light intensities that cover states from active photosynthesis, where all RCs are available for charge separation, to saturated photosynthesis where all RCs are unavailable. Our study outlines three key findings. First, there is a critical light-energy density, below which the low-light adapted membrane is more efficient at absorbing photons and generating a charge separation at RCs, than the high-light-adapted membrane. Second, connectivity of core complexes is similar in both membranes, suggesting that, despite different growth conditions, a preferred transfer pathway is through core-core contacts. Third, there may be minimal subareas on the membrane which, containing the same LH2:LH1 ratio, behave as minimal functional units as far as excitation transfer efficiency is concerned.

  1. Gaseous isotope separation using solar wind phenomena.

    PubMed

    Wang, C G

    1980-12-01

    A large evacuated drum-like chamber fitted with supersonic nozzles in the center, with the chamber and the nozzles corotating, can separate gaseous fluids according to their molecular weights. The principle of separation is essentially the same as that of the solar wind propagation, in which components of the plasma fluid are separated due to their difference in the time-of-flight. The process can inherently be very efficient, serving as a pump as well as a separator, and producing well over 10(5) separative work units (kg/year) for the hydrogen/deuterium mixture at high-velocity flows.

  2. Evaluation of a New Remote Handling Design for High Throughput Annular Centrifugal Contactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David H. Meikrantz; Troy G. Garn; Jack D. Law

    2009-09-01

    Advanced designs of nuclear fuel recycling plants are expected to include more ambitious goals for aqueous based separations including; higher separations efficiency, high-level waste minimization, and a greater focus on continuous processes to minimize cost and footprint. Therefore, Annular Centrifugal Contactors (ACCs) are destined to play a more important role for such future processing schemes. Previous efforts defined and characterized the performance of commercial 5 cm and 12.5 cm single-stage ACCs in a “cold” environment. The next logical step, the design and evaluation of remote capable pilot scale ACCs in a “hot” or radioactive environment was reported earlier. This reportmore » includes the development of remote designs for ACCs that can process the large throughput rates needed in future nuclear fuel recycling plants. Novel designs were developed for the remote interconnection of contactor units, clean-in-place and drain connections, and a new solids removal collection chamber. A three stage, 12.5 cm diameter rotor module has been constructed and evaluated for operational function and remote handling in highly radioactive environments. This design is scalable to commercial CINC ACC models from V-05 to V-20 with total throughput rates ranging from 20 to 650 liters per minute. The V-05R three stage prototype was manufactured by the commercial vendor for ACCs in the U.S., CINC mfg. It employs three standard V-05 clean-in-place (CIP) units modified for remote service and replacement via new methods of connection for solution inlets, outlets, drain and CIP. Hydraulic testing and functional checks were successfully conducted and then the prototype was evaluated for remote handling and maintenance suitability. Removal and replacement of the center position V-05R ACC unit in the three stage prototype was demonstrated using an overhead rail mounted PaR manipulator. This evaluation confirmed the efficacy of this innovative design for interconnecting and cleaning individual stages while retaining the benefits of commercially reliable ACC equipment for remote applications in the nuclear industry. Minor modifications and suggestions for improved manual remote servicing by the remote handling specialists were provided but successful removal and replacement was demonstrated in the first prototype.« less

  3. DNA Dendrimer: An Efficient Nanocarrier of Functional Nucleic Acids for Intracellular Molecular Sensing

    PubMed Central

    2015-01-01

    Functional nucleic acid (FNA)-based sensing systems have been developed for efficient detection of a wide range of biorelated analytes by employing DNAzymes or aptamers as recognition units. However, their intracellular delivery has always been a concern, mainly in delivery efficiency, kinetics, and the amount of delivered FNAs. Here we report a DNA dendrimer scaffold as an efficient nanocarrier to deliver FNAs and to conduct in situ monitoring of biological molecules in living cells. A histidine-dependent DNAzyme and an anti-ATP aptamer were chosen separately as the model FNAs to make the FNA dendrimer. The FNA-embedded DNA dendrimers maintained the catalytic activity of the DNAzyme or the aptamer recognition function toward ATP in the cellular environment, with no change in sensitivity or specificity. Moreover, these DNA dendrimeric nanocarriers show excellent biocompatibility, high intracellular delivery efficiency, and sufficient stability in a cellular environment. This FNA dendrimeric nanocarrier may find a broad spectrum of applications in biomedical diagnosis and therapy. PMID:24806614

  4. Attenuation - The Ugly Stepsister of Velocity in the Noise Correlation Family

    NASA Astrophysics Data System (ADS)

    Lawrence, J. F.; Prieto, G.; Denolle, M.; Seats, K. J.

    2012-12-01

    Noise correlation functions and noise transfer functions have shown in practice to preserve the relative amplitude information, despite the challenge to reliably resolve it compared to phase information. Yet amplitude contains important information about wavefield interactions with the subsurface structure, including focusing/defocusing and seismic attenuation. To focus on the anelastic effects, or attenuation, we measure amplitude decay with increased station separation (distance). We present numerical results showing that the noise correlation functions (NCFs) preserve the relative amplitude information and properly retrieve seismic attenuation for sufficient noise source distribution and appropriate processing. Attenuation is only preserved through the relative decay of distinct waves from multiple simultaneous source locations. With appropriate whitening (and no time domain normalization), the coherency preserves correlation amplitudes proportional to the relative decay expected with all the inter-station spacing. We present new attenuation results for the United States, and particularly the Yellowstone region that illustrate lateral variations that strongly correlate with known geological features such as sedimentary basins, crustal blocks and active volcanism.

  5. [Erectile function and ablative surgery of penile tumors].

    PubMed

    Pisani, E; Austoni, E; Trinchieri, A; Ceresoli, A; Mantovani, F; Colombo, F; Mastromarino, G; Vecchio, D; Canclini, L; Fenice, O

    1994-02-01

    The Authors try to show the possibility to combine radical excision with minimal invasiveness in the surgery of penile cancer. The focal point of every therapeutic decision is correct clinical staging. Unfortunately there's some confusion in the two international staging systems (TNM and Jackson's classification). In fact it's not clear the anatomical difference between epithelioma of the glans infiltrating corpus spongiosum and subcoronary epithelioma of the shaft infiltrating the corpora cavernosa. It's obvious that the infiltration of the corpora cavernosa is a far more aggressive oncological manifestation than that of tumour infiltrating the corpus spongiosum. So we consider Jackson's classification more congenial. In terms of surgery this anatomical independence makes it easy to consider the corpora cavernosa as a distinct entity, so they remain perfectly functional when separated from the glandulo-spongio-urethral unit with its vasculo-nervous bundle. This makes conservation of the erectile function, when clinical staging show us that the tumour is not infiltrating the corpora cavernosa. The Authors show their results, which seem to be rather good.

  6. Early life stress and physical and psychosocial functioning in late adulthood.

    PubMed

    Alastalo, Hanna; von Bonsdorff, Mikaela B; Räikkönen, Katri; Pesonen, Anu-Katriina; Osmond, Clive; Barker, David J P; Heinonen, Kati; Kajantie, Eero; Eriksson, Johan G

    2013-01-01

    Severe stress experienced in early life may have long-term effects on adult physiological and psychological health and well-being. We studied physical and psychosocial functioning in late adulthood in subjects separated temporarily from their parents in childhood during World War II. The 1803 participants belong to the Helsinki Birth Cohort Study, born 1934-44. Of them, 267 (14.8%) had been evacuated abroad in childhood during WWII and the remaining subjects served as controls. Physical and psychosocial functioning was assessed with the Short Form 36 scale (SF-36) between 2001 and 2004. A test for trends was based on linear regression. All analyses were adjusted for age at clinical examination, social class in childhood and adulthood, smoking, alcohol intake, physical activity, body mass index, cardiovascular disease and diabetes. Physical functioning in late adulthood was lower among the separated men compared to non-separated men (b = -0.40, 95% confidence interval [95% CI]: -0.71 to -0.08). Those men separated in school age (>7 years) and who were separated for a duration over 2 years had the highest risk for lower physical functioning (b = -0.89, 95% CI: -1.58 to -0.20) and (b = -0.65, 95% CI: -1.25 to -0.05), respectively). Men separated for a duration over 2 years also had lower psychosocial functioning (b = -0.70, 95% CI: -1.35 to -0.06). These differences in physical and psychosocial functioning were not observed among women. Early life stress may increase the risk for impaired physical functioning in late adulthood among men. Timing and duration of the separation influenced the physical and psychosocial functioning in late adulthood.

  7. Managing Lost and Missing Books

    ERIC Educational Resources Information Center

    Sewell, Bethany Badgett; Miller, Andrew Jonathan

    2008-01-01

    The University of Denver's Penrose Library's Stacks Maintenance unit is a separately managed unit that works in collaboration with all library departments to ensure complete access to the library's print collections. This unit takes advantage of a variety of techniques and tools to fulfill its mission, including a fine-tuned tracer system for…

  8. 40 CFR 60.1105 - How do I submit my final materials separation plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for Small Municipal Waste Combustion Units for Which Construction is Commenced After August 30, 1999... part of the notice of construction for the municipal waste combustion unit. Preconstruction...

  9. Flexible separator for alkaline batteries

    NASA Technical Reports Server (NTRS)

    Sheibley, D. W.

    1977-01-01

    Device is fabricated from low-cost readily-available commercial-materials by automated methods utilizing conventional paper coating processes. Flexibility of unit prevents cracking and disintegration caused by electrode warpage and dendrite growth, major causes of early battery failure with present separators.

  10. Single Wall Nanotube Type-Specific Functionalization and Separation

    NASA Technical Reports Server (NTRS)

    Boul, Peter; Nikolaev, Pavel; Sosa, Edward; Arepalli, Sivaram; Yowell, Leonard

    2008-01-01

    Metallic single-wall carbon nanotubes were selectively solubilized in THF and separated from semiconducting nanotubes. Once separated, the functionalized metallic tubes were de-functionalized to restore their metallic band structure. Absorption and Raman spectroscopy of the enriched samples support conclusions of the enrichment of nanotube samples by metallic type. A scalable method for enriching nanotube conductive type has been developed. Raman and UV-Vis data indicate SWCNT reaction with dodecylbenzenediazonium results in metallic enrichment. It is expected that further refinement of this techniques will lead to more dramatic separations of types and diameters.

  11. The Exoplanet Mass-Ratio Function From the MOA-II Survey: Discovery of a Break and Likely Peak at a Neptune Mass

    NASA Technical Reports Server (NTRS)

    Suzuki, D.; Bennett, D. P.; Sumi, T.; Bond, I. A.; Rogers, L. A.; Abe, F.; Asakura, Y.; Bhattacharya, A.; Donachie, M.; Freeman, M.; hide

    2016-01-01

    We report the results of the statistical analysis of planetary signals discovered in MOA-II microlensing survey alert system events from 2007 to 2012. We determine the survey sensitivity as a function of planet star mass ratio, q, and projected planet star separation, s, in Einstein radius units. We find that the mass-ratio function is not a single power law, but has a change in slope at q approx.10(exp -4), corresponding to approx. 20 Stellar Mass for the median host-star mass of approx. 0.6 M. We find significant planetary signals in 23 of the 1474 alert events that are well-characterized by the MOA-II survey data alone. Data from other groups are used only to characterize planetary signals that have been identified in the MOA data alone. The distribution of mass ratios and separations of the planets found in our sample are well fit by a broken power-law model. We also combine this analysis with the previous analyses of Gould et al. and Cassan et al., bringing the total sample to 30 planets. The unbroken power-law model is disfavored with a p-value of 0.0022, which corresponds to a Bayes factor of 27 favoring the broken power-law model. These results imply that cold Neptunes are likely to be the most common type of planets beyond the snow line.

  12. Anemonefish oxygenate their anemone hosts at night.

    PubMed

    Szczebak, Joseph T; Henry, Raymond P; Al-Horani, Fuad A; Chadwick, Nanette E

    2013-03-15

    Many stony coral-dwelling fishes exhibit adaptations to deal with hypoxia among the branches of their hosts; however, no information exists on the respiratory ecophysiology of obligate fish associates of non-coral organisms such as sea anemones and sponges. This study investigated metabolic and behavioral interactions between two-band anemonefish (Amphiprion bicinctus) and bulb-tentacle sea anemones (Entacmaea quadricolor) at night. We measured the net dark oxygen uptake ( , μmol O2 h(-1)) of fish-anemone pairs when partners were separate from each other, together as a unit, and together as a unit but separated by a mesh screen that prevented physical contact. We also measured the effects of water current on sea anemone and quantified the nocturnal behaviors of fish in the absence and presence of host anemones in order to discern the impacts of anemone presence on fish behavior. Net of united pairs was significantly higher than that of both separated pairs and united pairs that were separated by a mesh screen. Anemone increased with flow rate from 0.5 to 2.0 cm s(-1), after which remained constant up to a water flow rate of 8.0 cm s(-1). Furthermore, the percentage time and bout frequency of flow-modulating behaviors by fish increased significantly when anemones were present. We conclude that physical contact between anemonefish and sea anemones elevates the of at least one of the partners at night, and anemonefish behavior at night appears to oxygenate sea anemone hosts and to augment the metabolism of both partners.

  13. Methods for selective functionalization and separation of carbon nanotubes

    NASA Technical Reports Server (NTRS)

    Strano, Michael S. (Inventor); Usrey, Monica (Inventor); Barone, Paul (Inventor); Dyke, Christopher A. (Inventor); Tour, James M. (Inventor); Kittrell, W. Carter (Inventor); Hauge, Robert H (Inventor); Smalley, Richard E. (Inventor); Marek, legal representative, Irene Marie (Inventor)

    2011-01-01

    The present invention is directed toward methods of selectively functionalizing carbon nanotubes of a specific type or range of types, based on their electronic properties, using diazonium chemistry. The present invention is also directed toward methods of separating carbon nanotubes into populations of specific types or range(s) of types via selective functionalization and electrophoresis, and also to the novel compositions generated by such separations.

  14. Electronic wave function and binding effects in M-shell ionization of gold by protons

    NASA Astrophysics Data System (ADS)

    Pajek, M.; Banaś, D.; Jabłoński, Ł.; Mukoyama, T.

    2018-02-01

    The measured M-X-ray production cross sections for protons, which are used in the particle induced X-ray emission (PIXE) technique, are systematically underestimated for low impact energies by the ECPSSR and ECUSAR theories. These theories, which are based on the plane wave Born approximation (PWBA) and use the screened hydrogenic wave functions, include corrections for the projectile Coulomb deflection and electron relativistic and binding effects. In the present paper, in order to interpret the observed disagreement at low impact energies, the systematic calculations of the M-shell ionization cross sections for gold were performed using the semiclassical (SCA) and the binary encounter (BEA) approximations in order to identify a role of the electronic wave function and electron binding effects. In these calculations the different wave functions, from nonrelativistic hydrogenic to selfconsistent Dirac-Hartree-Fock, were considered and the binding effect was treated within extreme separated- (SA) and united-atoms (UA) limits. The results are discussed in details and the observed discrepancies are attributed to inadequate description of the electron binding effect at the lowest impact energies for which the molecular approach is required.

  15. A unique chromatin complex occupies young α-satellite arrays of human centromeres

    PubMed Central

    Henikoff, Jorja G.; Thakur, Jitendra; Kasinathan, Sivakanthan; Henikoff, Steven

    2015-01-01

    The intractability of homogeneous α-satellite arrays has impeded understanding of human centromeres. Artificial centromeres are produced from higher-order repeats (HORs) present at centromere edges, although the exact sequences and chromatin conformations of centromere cores remain unknown. We use high-resolution chromatin immunoprecipitation (ChIP) of centromere components followed by clustering of sequence data as an unbiased approach to identify functional centromere sequences. We find that specific dimeric α-satellite units shared by multiple individuals dominate functional human centromeres. We identify two recently homogenized α-satellite dimers that are occupied by precisely positioned CENP-A (cenH3) nucleosomes with two ~100–base pair (bp) DNA wraps in tandem separated by a CENP-B/CENP-C–containing linker, whereas pericentromeric HORs show diffuse positioning. Precise positioning is largely maintained, whereas abundance decreases exponentially with divergence, which suggests that young α-satellite dimers with paired ~100-bp particles mediate evolution of functional human centromeres. Our unbiased strategy for identifying functional centromeric sequences should be generally applicable to tandem repeat arrays that dominate the centromeres of most eukaryotes. PMID:25927077

  16. 75 FR 67960 - Notice of Availability of Draft National Pollutant Discharge Elimination System (NPDES) General...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    ... Discharge Elimination System (NPDES) General Permits for Small Municipal Separate Storm Sewer Systems (MS4... requirements of the CWA. The regulations at 40 CFR 122.26(b)(16) define a small municipal separate storm sewer system as ``* * * all separate storm sewers that are: (1) Owned or operated by the United States, a State...

  17. Deployment Support - Strength through Partnership

    DTIC Science & Technology

    2006-04-01

    Families are aware of and have access to relevant programs and services designed to help them manage CF- related separation and reunion...crises before, during and after periods of separation. • Families manage the challenges and circumstances associated with separation and reunion... business and the Personnel Support Program provides the family and the ship or unit with activities, refreshments and psychological supports. Families

  18. Proconsuls and CINCs from the Roman Republic to the Republic of the United States of America: Lessons for the Pax Americana

    DTIC Science & Technology

    2001-05-01

    find the best that foreign lands had to offer in constitutional theory. They found separation of powers within a mixed constitution. 60 The Greek...many of the Founding Fathers indeed knew Polybius, especially his passages on the Roman Constitution, and the separation of powers .”61 The separation ...lead 60 Marshall D. Lloyd, "Polybius and the Founding Fathers: the separation of powers ." Database on

  19. Basis convergence of range-separated density-functional theory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Franck, Odile, E-mail: odile.franck@etu.upmc.fr; Mussard, Bastien, E-mail: bastien.mussard@upmc.fr; CNRS, UMR 7616, Laboratoire de Chimie Théorique, F-75005 Paris

    2015-02-21

    Range-separated density-functional theory (DFT) is an alternative approach to Kohn-Sham density-functional theory. The strategy of range-separated density-functional theory consists in separating the Coulomb electron-electron interaction into long-range and short-range components and treating the long-range part by an explicit many-body wave-function method and the short-range part by a density-functional approximation. Among the advantages of using many-body methods for the long-range part of the electron-electron interaction is that they are much less sensitive to the one-electron atomic basis compared to the case of the standard Coulomb interaction. Here, we provide a detailed study of the basis convergence of range-separated density-functional theory. Wemore » study the convergence of the partial-wave expansion of the long-range wave function near the electron-electron coalescence. We show that the rate of convergence is exponential with respect to the maximal angular momentum L for the long-range wave function, whereas it is polynomial for the case of the Coulomb interaction. We also study the convergence of the long-range second-order Møller-Plesset correlation energy of four systems (He, Ne, N{sub 2}, and H{sub 2}O) with cardinal number X of the Dunning basis sets cc − p(C)V XZ and find that the error in the correlation energy is best fitted by an exponential in X. This leads us to propose a three-point complete-basis-set extrapolation scheme for range-separated density-functional theory based on an exponential formula.« less

  20. A Review of Function Allocation and En Route Separation Assurance

    NASA Technical Reports Server (NTRS)

    Lewis, Timothy A.; Aweiss, Arwa S.; Guerreiro, Nelson M.; Daiker, Ronald J.

    2016-01-01

    Today's air traffic control system has reached a limit to the number of aircraft that can be safely managed at the same time. This air traffic capacity bottleneck is a critical problem along the path to modernization for air transportation. The design of the next separation assurance system to address this problem is a cornerstone of air traffic management research today. This report reviews recent work by NASA and others in the areas of function allocation and en route separation assurance. This includes: separation assurance algorithms and technology prototypes; concepts of operations and designs for advanced separation assurance systems; and specific investigations into air-ground and human-automation function allocation.

  1. Activity and social factors affect cohesion among individuals in female Japanese macaques: A simultaneous focal-follow study.

    PubMed

    Nishikawa, Mari; Suzuki, Mariko; Sprague, David S

    2014-07-01

    Understanding cohesion among individuals within a group is necessary to reveal the social system of group-living primates. Japanese macaques (Macaca fuscata) are female-philopatric primates that reside in social groups. We investigated whether individual activity and social factors can affect spatio-temporal cohesion in wild female Japanese macaques. We conducted behavioral observation on a group, which contained 38 individuals and ranged over ca. 60 ha during the study period. Two observers carried out simultaneous focal-animal sampling of adult female pairs during full-day follows using global positioning system which enabled us to quantify interindividual distances (IIDs), group members within visual range (i.e., visual unit), and separation duration beyond visual range as indicators of cohesion among individuals. We found considerable variation in spatio-temporal group cohesion. The overall mean IID was 99.9 m (range = 0-618.2 m). The percentage of IIDs within visual range was 23.1%, within auditory range was 59.8%, and beyond auditory range was 17.1%. IIDs varied with activity; they were shorter during grooming and resting, and longer during foraging and traveling. Low-ranking females showed less cohesion than high-ranking ones. Kin females stayed nearly always within audible range. The macaques were weakly cohesive with small mean visual unit size (3.15 counting only adults, 5.99 counting all individuals). Both-sex units were the most frequently observed visual unit type when they were grooming/resting. Conversely, female units were the most frequently observed visual unit type when they were foraging. The overall mean visual separation duration was 25.7 min (range = 3-513 min). Separation duration was associated with dominance rank. These results suggest that Japanese macaques regulate cohesion among individuals depending on their activity and on social relationships; they were separated to adapt food distribution and aggregated to maintain social interactions. © 2014 Wiley Periodicals, Inc.

  2. Quantifying the physical demands of collision sports: does microsensor technology measure what it claims to measure?

    PubMed

    Gabbett, Tim J

    2013-08-01

    The physical demands of rugby league, rugby union, and American football are significantly increased through the large number of collisions players are required to perform during match play. Because of the labor-intensive nature of coding collisions from video recordings, manufacturers of wearable microsensor (e.g., global positioning system [GPS]) units have refined the technology to automatically detect collisions, with several sport scientists attempting to use these microsensors to quantify the physical demands of collision sports. However, a question remains over the validity of these microtechnology units to quantify the contact demands of collision sports. Indeed, recent evidence has shown significant differences in the number of "impacts" recorded by microtechnology units (GPSports) and the actual number of collisions coded from video. However, a separate study investigated the validity of a different microtechnology unit (minimaxX; Catapult Sports) that included GPS and triaxial accelerometers, and also a gyroscope and magnetometer, to quantify collisions. Collisions detected by the minimaxX unit were compared with video-based coding of the actual events. No significant differences were detected in the number of mild, moderate, and heavy collisions detected via the minimaxX units and those coded from video recordings of the actual event. Furthermore, a strong correlation (r = 0.96, p < 0.01) was observed between collisions recorded via the minimaxX units and those coded from video recordings of the event. These findings demonstrate that only one commercially available and wearable microtechnology unit (minimaxX) can be considered capable of offering a valid method of quantifying the contact loads that typically occur in collision sports. Until such validation research is completed, sport scientists should be circumspect of the ability of other units to perform similar functions.

  3. A general multiscale framework for the emergent effective elastodynamics of metamaterials

    NASA Astrophysics Data System (ADS)

    Sridhar, A.; Kouznetsova, V. G.; Geers, M. G. D.

    2018-02-01

    This paper presents a general multiscale framework towards the computation of the emergent effective elastodynamics of heterogeneous materials, to be applied for the analysis of acoustic metamaterials and phononic crystals. The generality of the framework is exemplified by two key characteristics. First, the underlying formalism relies on the Floquet-Bloch theorem to derive a robust definition of scales and scale separation. Second, unlike most homogenization approaches that rely on a classical volume average, a generalized homogenization operator is defined with respect to a family of particular projection functions. This yields a generalized macro-scale continuum, instead of the classical Cauchy continuum. This enables (in a micromorphic sense) to homogenize the rich dispersive behavior resulting from both Bragg scattering and local resonance. For an arbitrary unit cell, the homogenization projection functions are constructed using the Floquet-Bloch eigenvectors obtained in the desired frequency regime at select high symmetry points, which effectively resolves the emergent phenomena dominating that regime. Furthermore, a generalized Hill-Mandel condition is proposed that ensures power consistency between the homogenized and full-scale model. A high-order spatio-temporal gradient expansion is used to localize the multiscale problem leading to a series of recursive unit cell problems giving the appropriate micro-mechanical corrections. The developed multiscale method is validated against standard numerical Bloch analysis of the dispersion spectra of example unit cells encompassing multiple high-order branches generated by local resonance and/or Bragg scattering.

  4. Centralized versus distributed propulsion

    NASA Technical Reports Server (NTRS)

    Clark, J. P.

    1982-01-01

    The functions and requirements of auxiliary propulsion systems are reviewed. None of the three major tasks (attitude control, stationkeeping, and shape control) can be performed by a collection of thrusters at a single central location. If a centralized system is defined as a collection of separated clusters, made up of the minimum number of propulsion units, then such a system can provide attitude control and stationkeeping for most vehicles. A distributed propulsion system is characterized by more numerous propulsion units in a regularly distributed arrangement. Various proposed large space systems are reviewed and it is concluded that centralized auxiliary propulsion is best suited to vehicles with a relatively rigid core. These vehicles may carry a number of flexible or movable appendages. A second group, consisting of one or more large flexible flat plates, may need distributed propulsion for shape control. There is a third group, consisting of vehicles built up from multiple shuttle launches, which may be forced into a distributed system because of the need to add additional propulsion units as the vehicles grow. The effects of distributed propulsion on a beam-like structure were examined. The deflection of the structure under both translational and rotational thrusts is shown as a function of the number of equally spaced thrusters. When two thrusters only are used it is shown that location is an important parameter. The possibility of using distributed propulsion to achieve minimum overall system weight is also examined. Finally, an examination of the active damping by distributed propulsion is described.

  5. Interrelated chemical-microstructural-nanomechanical variations in the structural units of the cuttlebone of Sepia officinalis

    NASA Astrophysics Data System (ADS)

    North, L.; Labonte, D.; Oyen, M. L.; Coleman, M. P.; Caliskan, H. B.; Johnston, R. E.

    2017-11-01

    "Cuttlebone," the internalized shell found in all members of the cephalopod family Sepiidae, is a sophisticated buoyancy device combining high porosity with considerable strength. Using a complementary suite of characterization tools, we identified significant structural, chemical, and mechanical variations across the different structural units of the cuttlebone: the dorsal shield consists of two stiff and hard layers with prismatic mineral organization which encapsulate a more ductile and compliant layer with a lamellar structure, enriched with organic matter. A similar organization is found in the chambers, which are separated by septa, and supported by meandering plates ("pillars"). Like the dorsal shield, septa contain two layers with lamellar and prismatic organization, respectively, which differ significantly in their mechanical properties: layers with prismatic organization are a factor of three stiffer and up to a factor of ten harder than those with lamellar organization. The combination of stiff and hard, and compliant and ductile components may serve to reduce the risk of catastrophic failure, and reflect the role of organic matter for the growth process of the cuttlebone. Mechanically "weaker" units may function as sacrificial structures, ensuring a stepwise failure of the individual chambers in cases of overloading, allowing the animals to retain near-neutral buoyancy even with partially damaged cuttlebones. Our findings have implications for our understanding of the structure-property-function relationship of cuttlebone, and may help to identify novel bioinspired design strategies for light-weight yet high-strength foams.

  6. 33 CFR 328.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 CFR 423.11(m) which also meet the criteria of this definition) are not waters of the United States... neighboring. Wetlands separated from other waters of the United States by man-made dikes or barriers, natural...

  7. Direct condensation refrigerant recovery and restoration system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grant, D.C.H.

    1992-03-10

    This patent describes a refrigerant recovery and purification system for removing gaseous refrigerant from a disabled refrigeration unit, cleaning the refrigerant of contaminants, and converting the gaseous refrigerant to a liquid state for storage. It comprises a low pressure inlet section; a high pressure storage section; the low pressure inlet section comprising: an oil and refrigerant gas separator, including a separated oil removal means, first conduit means for connecting an inlet of the separator to the disabled refrigerant unit, a slack-sided accumulator, second conduit means connecting the separator to the slack-sided accumulator, a reclaim condenser, third conduit means connecting themore » separator and the reclaim condenser in series, an evaporator coil in the reclaim condenser connectable to a conventional operating refrigeration system for receiving a liquid refrigerant under pressure for expansion therein, the evaporator coil forming a condensing surface for condensing the refrigerant gas at near atmospheric pressure in the condenser, a liquid receiver, a reclaimed refrigerant storage tank, fourth conduit means further connecting the liquid receiver in series with the reclaim condenser, downstream thereof, means between the reclaim condenser and the liquid receiver.« less

  8. Living Together Apart in France and the United States

    PubMed Central

    Martin, Claude; Cherlin, Andrew; Cross-Barnet, Caitlin

    2014-01-01

    Union formation involves a number of stages, as does union dissolution, and new couples often spend an initial period in a non-cohabiting intimate relationship. Yet while certain couples never share the same dwelling, “living apart together”1 has not developed widely as a long-term lifestyle option. Claude Martin in France, and Andrew Cherlin and Caitlin Cross-Barnet in the United States have studied a symmetrical phenomenon, that of couples who continue to live together while considering themselves to be separated. In this article, they draw together their analyses to describe an arrangement which, while marginal, reveals situations where residential separation is not possible, either because of the need to keep up appearances, often for the children’s sake, or because total separation is too frightening or living in separate homes is unaffordable. Beyond the differences between the two countries and the two survey fields, the authors analyse the ways in which persons who “live together apart” describe their loveless relationship that has led to explicit conjugal separation within a shared home. PMID:25170338

  9. Is the orthographic/phonological onset a single unit in reading aloud?

    PubMed

    Mousikou, Petroula; Coltheart, Max; Saunders, Steven; Yen, Lisa

    2010-02-01

    Two main theories of visual word recognition have been developed regarding the way orthographic units in printed words map onto phonological units in spoken words. One theory suggests that a string of single letters or letter clusters corresponds to a string of phonemes (Coltheart, 1978; Venezky, 1970), while the other suggests that a string of single letters or letter clusters corresponds to coarser phonological units, for example, onsets and rimes (Treiman & Chafetz, 1987). These theoretical assumptions were critical for the development of coding schemes in prominent computational models of word recognition and reading aloud. In a reading-aloud study, we tested whether the human reading system represents the orthographic/phonological onset of printed words and nonwords as single units or as separate letters/phonemes. Our results, which favored a letter and not an onset-coding scheme, were successfully simulated by the dual-route cascaded (DRC) model (Coltheart, Rastle, Perry, Langdon, & Ziegler, 2001). A separate experiment was carried out to further adjudicate between 2 versions of the DRC model.

  10. Multi-tasking computer control of video related equipment

    NASA Technical Reports Server (NTRS)

    Molina, Rod; Gilbert, Bob

    1989-01-01

    The flexibility, cost-effectiveness and widespread availability of personal computers now makes it possible to completely integrate the previously separate elements of video post-production into a single device. Specifically, a personal computer, such as the Commodore-Amiga, can perform multiple and simultaneous tasks from an individual unit. Relatively low cost, minimal space requirements and user-friendliness, provides the most favorable environment for the many phases of video post-production. Computers are well known for their basic abilities to process numbers, text and graphics and to reliably perform repetitive and tedious functions efficiently. These capabilities can now apply as either additions or alternatives to existing video post-production methods. A present example of computer-based video post-production technology is the RGB CVC (Computer and Video Creations) WorkSystem. A wide variety of integrated functions are made possible with an Amiga computer existing at the heart of the system.

  11. Quantifying Health Status and Function in Marfan Syndrome.

    PubMed

    Rao, Sandesh S; Venuti, Kristen D; Dietz, Harry C; Sponseller, Paul D

    2016-01-01

    Two hundred thirty patients were prospectively enrolled in this study and completed various portions of the Short Form 36 and a study-specific questionnaire (visual analog scale 1 to 10, comprising three separate questionnaires) to evaluate quality of life and function in patients with Marfan syndrome. The greatest health concern was cardiac problems (high in 70% of patients), followed by spine issues and generalized fatigue (both high, in 53%). The most severe reported pain involved the back: 105 patients (46%) rated pain as 6 to 10 on the visual analog scale. Among the 72 patients who responded to work life questions, work hours were reduced because of treatment in 59 (82%) or directly because of Marfan syndrome in 29 (40%). Across all Short Form 36 domains, patients scored significantly lower than United States population norms (p<.05); physical health scores were considerably lower than mental health scores.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leung, P. T.; Young, K.

    Reciprocity in wave propagation usually refers to the symmetry of the Green's function under the interchange of the source and the observer coordinates, but this condition is not gauge invariant in quantum mechanics, a problem that is particularly significant in the presence of a vector potential. Several possible alternative criteria are given and analyzed with reference to different examples with nonzero magnetic fields and/or vector potentials, including the case of a multiply connected spatial domain. It is shown that the appropriate reciprocity criterion allows for specific phase factors separable into functions of the source and observer coordinates and that thismore » condition is robust with respect to the addition of any scalar potential. In the Aharonov-Bohm effect, reciprocity beyond monoenergetic experiments holds only because of subsidiary conditions satisfied in actual experiments: the test charge is in units of e and the flux is produced by a condensate of particles with charge 2e.« less

  13. Separating macroecological pattern and process: comparing ecological, economic, and geological systems.

    PubMed

    Blonder, Benjamin; Sloat, Lindsey; Enquist, Brian J; McGill, Brian

    2014-01-01

    Theories of biodiversity rest on several macroecological patterns describing the relationship between species abundance and diversity. A central problem is that all theories make similar predictions for these patterns despite disparate assumptions. A troubling implication is that these patterns may not reflect anything unique about organizational principles of biology or the functioning of ecological systems. To test this, we analyze five datasets from ecological, economic, and geological systems that describe the distribution of objects across categories in the United States. At the level of functional form ('first-order effects'), these patterns are not unique to ecological systems, indicating they may reveal little about biological process. However, we show that mechanism can be better revealed in the scale-dependency of first-order patterns ('second-order effects'). These results provide a roadmap for biodiversity theory to move beyond traditional patterns, and also suggest ways in which macroecological theory can constrain the dynamics of economic systems.

  14. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets

    PubMed Central

    Macosko, Evan Z.; Basu, Anindita; Satija, Rahul; Nemesh, James; Shekhar, Karthik; Goldman, Melissa; Tirosh, Itay; Bialas, Allison R.; Kamitaki, Nolan; Martersteck, Emily M.; Trombetta, John J.; Weitz, David A.; Sanes, Joshua R.; Shalek, Alex K.; Regev, Aviv; McCarroll, Steven A.

    2015-01-01

    Summary Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of ease and scale have prevented its broad application. Here we describe Drop-Seq, a strategy for quickly profiling thousands of individual cells by separating them into nanoliter-sized aqueous droplets, associating a different barcode with each cell’s RNAs, and sequencing them all together. Drop-Seq analyzes mRNA transcripts from thousands of individual cells simultaneously while remembering transcripts’ cell of origin. We analyzed transcriptomes from 44,808 mouse retinal cells and identified 39 transcriptionally distinct cell populations, creating a molecular atlas of gene expression for known retinal cell classes and novel candidate cell subtypes. Drop-Seq will accelerate biological discovery by enabling routine transcriptional profiling at single-cell resolution. PMID:26000488

  15. Directional statistics-based reflectance model for isotropic bidirectional reflectance distribution functions.

    PubMed

    Nishino, Ko; Lombardi, Stephen

    2011-01-01

    We introduce a novel parametric bidirectional reflectance distribution function (BRDF) model that can accurately encode a wide variety of real-world isotropic BRDFs with a small number of parameters. The key observation we make is that a BRDF may be viewed as a statistical distribution on a unit hemisphere. We derive a novel directional statistics distribution, which we refer to as the hemispherical exponential power distribution, and model real-world isotropic BRDFs as mixtures of it. We derive a canonical probabilistic method for estimating the parameters, including the number of components, of this novel directional statistics BRDF model. We show that the model captures the full spectrum of real-world isotropic BRDFs with high accuracy, but a small footprint. We also demonstrate the advantages of the novel BRDF model by showing its use for reflection component separation and for exploring the space of isotropic BRDFs.

  16. The reliability analysis of a separated, dual fail operational redundant strapdown IMU. [inertial measurement unit

    NASA Technical Reports Server (NTRS)

    Motyka, P.

    1983-01-01

    A methodology for quantitatively analyzing the reliability of redundant avionics systems, in general, and the dual, separated Redundant Strapdown Inertial Measurement Unit (RSDIMU), in particular, is presented. The RSDIMU is described and a candidate failure detection and isolation system presented. A Markov reliability model is employed. The operational states of the system are defined and the single-step state transition diagrams discussed. Graphical results, showing the impact of major system parameters on the reliability of the RSDIMU system, are presented and discussed.

  17. Process for producing fuel grade ethanol by continuous fermentation, solvent extraction and alcohol separation

    DOEpatents

    Tedder, Daniel W.

    1985-05-14

    Alcohol substantially free of water is prepared by continuously fermenting a fermentable biomass feedstock in a fermentation unit, thereby forming an aqueous fermentation liquor containing alcohol and microorganisms. Continuously extracting a portion of alcohol from said fermentation liquor with an organic solvent system containing an extractant for said alcohol, thereby forming an alcohol-organic solvent extract phase and an aqueous raffinate. Said alcohol is separated from said alcohol-organic solvent phase. A raffinate comprising microorganisms and unextracted alcohol is returned to the fermentation unit.

  18. Within-unit relationship quality mediates the association between military sexual trauma and posttraumatic stress symptoms in veterans separating from military service.

    PubMed

    Laws, Holly; Mazure, Carolyn M; McKee, Sherry A; Park, Crystal L; Hoff, Rani

    2016-09-01

    Few studies have examined the impact of military sexual trauma (MST) on social functioning during deployment. Yet consideration of unit relationships during deployment may be important, given that military unit cohesion and support can provide protective effects against the stress of combat, and reduce the likelihood of developing posttraumatic stress disorder. Although prior research has posited that depleted social resources are one pathway through which MST is associated with posttraumatic stress symptoms (PTSS), no studies have statistically tested this theory. This study examined the association of MST and PTSS and evaluated the potential mediating role of decreased unit relationship quality. Mediational analyses were conducted on a sample of veterans following discharge from military service (N = 818; 328 women, 490 men). Women were significantly more likely to experience MST than men. As hypothesized, experiences of MST during deployment were associated with higher PTSS. MST experiences were associated with less trust in and support from one's military unit, which partially mediated the association between MST and PTSS. The indirect effect of MST on PTSS through lower unit relationship quality accounted for 20.4% of the total effect of MST on PTSS. While the retrospective study design precludes tests of causality, mediational findings provided statistical evidence that lower unit relationship quality partially explains the association between MST and PTSS. This finding is consistent with interpersonal theories of trauma response suggesting that the deleterious effects of MST may be in part due to its erosion of social resources during deployment. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  19. Whose Culture?: Monolithic Cultures and Subcultures in Early Childhood Settings

    ERIC Educational Resources Information Center

    Halttunen, Leena

    2017-01-01

    In Finland, day care centre directors have traditionally led only a single unit, but after the recent merging of many units, most directors simultaneously lead several, physically separate units. These organizations are called distributed organizations. This study was carried out in two distributed day care organizations. The findings are based on…

  20. Good Work! Instructor's Guide. Revised. Employability Skills Series.

    ERIC Educational Resources Information Center

    Farrow, Douglas R.

    This instructor's guide accompanies the student booklet/unit on good work habits/behaviors in the Employability Skills Series. (The student booklet is available separately as CE 031 161.) It first discusses the Employability Skills Series. A section on administering the unit details purpose of the unit and major concepts to be developed, lists…

  1. 46 CFR 161.002-8 - Automatic fire detecting systems, general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... detecting system shall consist of a power supply; a control unit on which are located visible and audible... control unit. Power failure alarm devices may be separately housed from the control unit and may be combined with other power failure alarm systems when specifically approved. (b) [Reserved] [21 FR 9032, Nov...

  2. 46 CFR 161.002-8 - Automatic fire detecting systems, general requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... detecting system shall consist of a power supply; a control unit on which are located visible and audible... control unit. Power failure alarm devices may be separately housed from the control unit and may be combined with other power failure alarm systems when specifically approved. (b) [Reserved] [21 FR 9032, Nov...

  3. Flow-Control Unit For Nitrogen And Hydrogen Gases

    NASA Technical Reports Server (NTRS)

    Chang, B. J.; Novak, D. W.

    1990-01-01

    Gas-flow-control unit installed and removed as one piece replaces system that included nine separately serviced components. Unit controls and monitors flows of nitrogen and hydrogen gases. Designed for connection via fluid-interface manifold plate, reducing number of mechanical fluid-interface connections from 18 to 1. Unit provides increasing reliability, safety, and ease of maintenance, and for reducing weight, volume, and power consumption.

  4. Functioning of inorganic/organic battery separators in silver-zinc cells

    NASA Technical Reports Server (NTRS)

    Philipp, W. H.; May, C. E.

    1976-01-01

    The results of three experimental studies related to the inorganic/organic battery separator operating mechanism are described: saponification of the plasticizer, resistivity of the simulated separators, and zincate diffusion through the separators. The inorganic/organic separator appears to be a particular example of a general class of ionic conducting films composed of inorganic fillers and/or substrates bonded together by an organic polymer containing an incompatible plasticizer that may be leached by the electrolyte. The I/O separator functions as a microporous film of varying tortuosity with essentially no specific chemical inhibition to zincate diffusion.

  5. Cumulant-based expressions for the multibody terms for the correlation between local and electrostatic interactions in the united-residue force field

    NASA Astrophysics Data System (ADS)

    Liwo, Adam; Czaplewski, Cezary; Pillardy, Jarosław; Scheraga, Harold A.

    2001-08-01

    A general method to derive site-site or united-residue potentials is presented. The basic principle of the method is the separation of the degrees of freedom of a system into the primary and secondary ones. The primary degrees of freedom describe the basic features of the system, while the secondary ones are averaged over when calculating the potential of mean force, which is hereafter referred to as the restricted free energy (RFE) function. The RFE can be factored into one-, two-, and multibody terms, using the cluster-cumulant expansion of Kubo. These factors can be assigned the functional forms of the corresponding lowest-order nonzero generalized cumulants, which can, in most cases, be evaluated analytically, after making some simplifying assumptions. This procedure to derive coarse-grain force fields is very valuable when applied to multibody terms, whose functional forms are hard to deduce in another way (e.g., from structural databases). After the functional forms have been derived, they can be parametrized based on the RFE surfaces of model systems obtained from all-atom models or on the statistics derived from structural databases. The approach has been applied to our united-residue force field for proteins. Analytical expressions were derived for the multibody terms pertaining to the correlation between local and electrostatic interactions within the polypeptide backbone; these expressions correspond to up to sixth-order terms in the cumulant expansion of the RFE. These expressions were subsequently parametrized by fitting to the RFEs of selected peptide fragments, calculated with the empirical conformational energy program for peptides force field. The new multibody terms enable not only the heretofore predictable α-helical segments, but also regular β-sheets, to form as the lowest-energy structures, as assessed by test calculations on a model helical protein A, as well as a model 20-residue polypeptide (betanova); the latter was not possible without introducing these new terms.

  6. Evaluation of Innovative Volatile Organic Compound and Hazardous Air Pollutant Control Technologies for U.S. Air Force Paint Spray Booths

    DTIC Science & Technology

    1990-10-01

    adsorption/incineration * Membrane vapor separation/condensation * Supercritical fluid oxidation • UV/ozone destruction * Molten salt combustion process...separation/ separate air stream contaminants 9 Oxygenated solvents condensation * Chlorinated hydrocarbons Supercritical fluid * Technology utilizing high...testing or full-scale unit capacity; they are: * Supercritical fluid oxidation • UV/ozone destruction * Molten salt incineration * Infrared incineration

  7. A Compelling Solution to Guantanamo Bay

    DTIC Science & Technology

    2013-03-01

    military commission violated separation of powers because one branch of the government, namely the Executive, controlled all aspects of the case... separation of powers requirement. The conclusion that can be drawn from these legal decisions is that the military system is fundamentally...the Rule of Law and violates the separation of powers .111 The current system has even strained the United States’ relationship with close allies

  8. Impact of Pilot Delay and Non-Responsiveness on the Safety Performance of Airborne Separation

    NASA Technical Reports Server (NTRS)

    Consiglio, Maria; Hoadley, Sherwood; Wing, David; Baxley, Brian; Allen, Bonnie Danette

    2008-01-01

    Assessing the safety effects of prediction errors and uncertainty on automationsupported functions in the Next Generation Air Transportation System concept of operations is of foremost importance, particularly safety critical functions such as separation that involve human decision-making. Both ground-based and airborne, the automation of separation functions must be designed to account for, and mitigate the impact of, information uncertainty and varying human response. This paper describes an experiment that addresses the potential impact of operator delay when interacting with separation support systems. In this study, we evaluated an airborne separation capability operated by a simulated pilot. The experimental runs are part of the Safety Performance of Airborne Separation (SPAS) experiment suite that examines the safety implications of prediction errors and system uncertainties on airborne separation assistance systems. Pilot actions required by the airborne separation automation to resolve traffic conflicts were delayed within a wide range, varying from five to 240 seconds while a percentage of randomly selected pilots were programmed to completely miss the conflict alerts and therefore take no action. Results indicate that the strategicAirborne Separation Assistance System (ASAS) functions exercised in the experiment can sustain pilot response delays of up to 90 seconds and more, depending on the traffic density. However, when pilots or operators fail to respond to conflict alerts the safety effects are substantial, particularly at higher traffic densities.

  9. 9 CFR 381.196 - Eligibility of foreign countries for importation of poultry products into the United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... processed for export to the United States; (E) Complete separation of establishments certified under... potential contaminants, in accordance with sampling and analytical techniques approved by the Administrator...

  10. 9 CFR 381.196 - Eligibility of foreign countries for importation of poultry products into the United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... processed for export to the United States; (E) Complete separation of establishments certified under... potential contaminants, in accordance with sampling and analytical techniques approved by the Administrator...

  11. 9 CFR 381.196 - Eligibility of foreign countries for importation of poultry products into the United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... processed for export to the United States; (E) Complete separation of establishments certified under... potential contaminants, in accordance with sampling and analytical techniques approved by the Administrator...

  12. Ammonium salt corrosion in hydrotreating unit stripper column overhead systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shargay, C.A.; Jacobs, G.E.; Price, M.D.

    In the past, the presence of ammonium bisulfide (NH{sub 4}HS) or ammonium chloride (NH{sub 4}Cl) in hydrotreater stripper overheads was relatively rare. However, designs of newer units and revamps to older units, are resulting in corrosive levels of NH{sub 4}HS or NH{sub 4}Cl in overhead systems. This is primarily due to the addition of a hot high pressure separator (HHPS) with the bottoms going directly (or through another separator) to the stripper. This paper presents data on one corrosion case history in detail, a summary of another case history reported in Retln-Cor 3.0 and the results of a brief surveymore » targeted to units with HHPS designs. Some correlations of the process conditions to the severity of corrosion are made based on the survey results, and recommended materials selection and other corrosion control methods to minimize the risk of this problem are given.« less

  13. Theoretical Studies of the Kinetics of First-Order Phase Transitions.

    NASA Astrophysics Data System (ADS)

    Zheng, Qiang

    This thesis involves theoretical studies of the kinetics of orderings in three classes of systems. The first class involves problems of phase separation in which the order parameter is conserved, such as occurs in the binary alloy Al-Zn. A theory is developed for the late stages of phase separation in the droplet regime for two -dimensional systems, namely, Ostwald ripening in two dimensions. The theory considers droplet correlations, which was neglected before, by a proper treatment of the screening effect of the correlations. This correlation effect is found that it does not alert the scaling features of phase separation, but significantly changes the shape of droplet-size distribution function. Further experiments and computer simulations are needed before this long-time subject may be closed. A second class of problem involves a study of the finite-size effects on domain growth described by the Allen-Cahn dynamics. Based on a theoretical approach of Ohta, Jasnow, and Kawasaki the explicit scaling functions for the scattering intensity for hypercubes and films are obtained. These results are for the cases in which the order-parameter is not conserved, such as in an order-disorder transition in alloys. These studies will be relevant to the experimental and computer simulation research projects currently being carried out in the United States and Europe. The last class of problems involves orderings in strong correlated systems, namely, the growth of Breath Figures. A special feature of this class of problems is that the coalescence effect. A theoretical model is proposed which can handle the two growth mechanisms, the individual droplet growth and coalescence simultaneously. Under certain approximations, the droplet-size distribution function is obtained analytically, and is in qualitative agreement with computer simulations. Our model also suggests that there may be an interesting relationship between the growth of Breath Figures and a geometric structure (ultrametricity) of general complex systems.

  14. Capillary electrophoresis of covalently functionalized single-chirality carbon nanotubes.

    PubMed

    He, Pingli; Meany, Brendan; Wang, Chunyan; Piao, Yanmei; Kwon, Hyejin; Deng, Shunliu; Wang, YuHuang

    2017-07-01

    We demonstrate the separation of chirality-enriched single-walled carbon nanotubes (SWCNTs) by degree of surface functionalization using high-performance CE. Controlled amounts of negatively charged and positively charged functional groups were attached to the sidewall of chirality-enriched SWCNTs through covalent functionalization using 4-carboxybenzenediazonium tetrafluoroborate or 4-diazo-N,N-diethylaniline tetrafluoroborate, respectively. Surfactant- and pH-dependent studies confirmed that under conditions that minimized ionic screening effects, separation of these functionalized SWCNTs was strongly dependent on the surface charge density introduced through covalent surface chemistry. For both heterogeneous mixtures and single-chirality-enriched samples, covalently functionalized SWCNTs showed substantially increased peak width in electropherogram spectra compared to nonfunctionalized SWCNTs, which can be attributed to a distribution of surface charges along the functionalized nanotubes. Successful separation of functionalized single-chirality SWCNTs by functional density was confirmed with UV-Vis-NIR absorption and Raman scattering spectroscopies of fraction collected samples. These results suggest a high degree of structural heterogeneity in covalently functionalized SWCNTs, even for chirality-enriched samples, and show the feasibility of applying CE for high-performance separation of nanomaterials based on differences in surface functional density. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Electronic scraps--recovering of valuable materials from parallel wire cables.

    PubMed

    de Araújo, Mishene Christie Pinheiro Bezerra; Chaves, Arthur Pinto; Espinosa, Denise Crocce Romano; Tenório, Jorge Alberto Soares

    2008-11-01

    Every year, the number of discarded electro-electronic products is increasing. For this reason recycling is needed, to avoid wasting non-renewable natural resources. The objective of this work is to study the recycling of materials from parallel wire cable through unit operations of mineral processing. Parallel wire cables are basically composed of polymer and copper. The following unit operations were tested: grinding, size classification, dense medium separation, electrostatic separation, scrubbing, panning, and elutriation. It was observed that the operations used obtained copper and PVC concentrates with a low degree of cross contamination. It was concluded that total liberation of the materials was accomplished after grinding to less than 3 mm, using a cage mill. Separation using panning and elutriation presented the best results in terms of recovery and cross contamination.

  16. Atmosphere-entry behavior of a modular, disk-shaped, isotope heat source.

    NASA Technical Reports Server (NTRS)

    Vorreiter, J. W.; Pitts, W. C.; Stine, H. A.; Burns, J. J.

    1973-01-01

    The authors have studied the entry and impact behavior of an isotope heat source for space nuclear power that disassembles into a number of modules which would enter the earth's atmosphere separately if a flight aborted. These modules are disk-shaped units, each with its own reentry heat shield and protective impact container. In normal operation, the disk modules are stacked inside the generator, but during a reentry abort they separate and fly as individual units of low ballistic coefficient. Flight tests at hypersonic speeds have confirmed that a stack of disks will separate and assume a flat-forward mode of flight. Free-fall tests of single disks have demonstrated a nominal impact velocity of 30 m/sec at sea level for a practical range of ballistic coefficients.

  17. Whole blood coagulation analyzers.

    PubMed

    1997-08-01

    Whole blood Coagulation analyzers (WBCAs) are widely used point-of-care (POC) testing devices found primarily in cardiothoracic surgical suites and cardia catheterization laboratories. Most of these devices can perform a number of coagulation tests that provide information about a patient's blood clotting status. Clinicians use the results of the WBCA tests, which are available minutes after applying a blood sample, primarily to monitor the effectiveness of heparin therapy--an anticoagulation therapy used during cardiopulmonary bypass (CPB) surgery, angioplasty, hemodialysis, and other clinical procedures. In this study we evaluated five WBCAs from four suppliers. Our testing focused on the applications for which WBCAs are primarily used: Monitoring moderate to high heparin levels, as would be required, for example, during CPB are angioplasty. For this function, WCBAs are typically used to perform an activated clotting time (ACT) test or, as one supplier refers to its test, a heparin management test (HMT). All models included in this study offered an ACT test or an HMT. Monitoring low heparin levels, as would be required, for example,during hemodialysis. For this function, WBCAs would normally be used to perform either a low-range ACT (LACT) test or a whole blood activated partial thromboplastin time (WBAPTT) test. Most of the evaluated units could perform at least one of these tests; one unit did not offer either test and was therefore not rated for this application. We rated and ranked each evaluated model separately for each of these two applications. In addition, we provided a combined rating and ranking that considers the units' appropriateness for performing both application. We based our conclusions on a unit's performance and humans factor design, as determined by our testing, and on its five-year life-cycle cost, as determined by our net present value (NPV) analysis. While we rated all evaluated units acceptable for each appropriate category, we did identify some significant differences that enabled us to rank the units in order of preference. We have included a Selection, Purchasing, and use guide at the end of this study to help facilities identify the unit that will best meet their needs.

  18. Small changes in lung function in runners with marathon‐induced interstitial lung edema

    PubMed Central

    Zavorsky, Gerald S.; Milne, Eric N.C.; Lavorini, Federico; Rienzi, Joseph P.; Cutrufello, Paul T.; Kumar, Sridhar S.; Pistolesi, Massimo

    2014-01-01

    Abstract The purpose of this study was to assess lung function in runners with marathon‐induced lung edema. Thirty‐six (24 males) healthy subjects, 34 (SD 9) years old, body mass index 23.7 (2.6) kg/m2 had posterior/anterior (PA) radiographs taken 1 day before and 21 (6) minutes post marathon finish. Pulmonary function was performed 1–3 weeks before and 73 (27) minutes post finish. The PA radiographs were viewed together, as a set, and evaluated by two experienced readers separately who were blinded as to time the images were obtained. Radiographs were scored for edema based on four different radiological characteristics such that the summed scores for any runner could range from 0 (no edema) to a maximum of 8 (severe interstitial edema). Overall, the mean edema score increased significantly from 0.2 to 1.0 units (P <0.01), and from 0.0 to 2.9 units post exercise in the six subjects that were edema positive (P = 0.03). Despite a 2% decrease in forced vital capacity (FVC, P =0.024) and a 12% decrease in alveolar‐membrane diffusing capacity for carbon monoxide (DmCO, P =0.01), there was no relation between the change in the edema score and the change in DmCO or FVC. In conclusion, (1) mild pulmonary edema occurs in at least 17% of subjects and that changes in pulmonary function cannot predict the occurrence or severity of edema, (2) lung edema is of minimal physiological significance as marathon performance is unaffected, exercise‐induced arterial hypoxemia is unlikely, and postexercise pulmonary function changes are mild. PMID:24973330

  19. Metal-air flow batteries using oxygen enriched electrolyte

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zheng, Jian-ping; Andrei, Petru; Shellikeri, Annadanesh

    A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed.

  20. Metal-air flow batteries using oxygen enriched electrolyte

    DOEpatents

    Zheng, Jian-ping; Andrei, Petru; Shellikeri, Annadanesh; Chen, Xujie

    2017-08-01

    A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed.

  1. Endoscopic sensing of alveolar pH.

    PubMed

    Choudhury, D; Tanner, M G; McAughtrie, S; Yu, F; Mills, B; Choudhary, T R; Seth, S; Craven, T H; Stone, J M; Mati, I K; Campbell, C J; Bradley, M; Williams, C K I; Dhaliwal, K; Birks, T A; Thomson, R R

    2017-01-01

    Previously unobtainable measurements of alveolar pH were obtained using an endoscope-deployable optrode. The pH sensing was achieved using functionalized gold nanoshell sensors and surface enhanced Raman spectroscopy (SERS). The optrode consisted of an asymmetric dual-core optical fiber designed for spatially separating the optical pump delivery and signal collection, in order to circumvent the unwanted Raman signal generated within the fiber. Using this approach, we demonstrate a ~100-fold increase in SERS signal-to-fiber background ratio, and demonstrate multiple site pH sensing with a measurement accuracy of ± 0.07 pH units in the respiratory acini of an ex vivo ovine lung model. We also demonstrate that alveolar pH changes in response to ventilation.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Ying

    My graduate research has focused on separation science and bioanalytical analysis, which emphasized in method development. It includes three major areas: enantiomeric separations using high performance liquid chromatography (HPLC), Super/subcritical fluid chromatography (SFC), and capillary electrophoresis (CE); drug-protein binding behavior studies using CE; and carbohydrate analysis using liquid chromatograph-electrospray ionization mass spectrometry (LC-ESI-MS). Enantiomeric separations continue to be extremely important in the pharmaceutical industry. An in-depth evaluation of the enantiomeric separation capabilities of macrocyclic glycopeptides CSPs with SFC mobile phases was investigated using a set of over 100 chiral compounds. It was found that the macrocyclic based CSPs were ablemore » to separate enantiomers of various compounds with different polarities and functionalities. Seventy percent of all separations were achieved in less than 4 min due to the high flow rate (4.0 ml/min) that can be used in SFC. Drug-protein binding is an important process in determining the activity and fate of a drug once it enters the body. Two drug/protein systems have been studied using frontal analysis CE method. More sensitive fluorescence detection was introduced in this assay, which overcame the problem of low sensitivity that is common when using UV detection for drug-protein studies. In addition, the first usage of an argon ion laser with 257 nm beam coupled with CCD camera as a frontal analysis detection method enabled the simultaneous observation of drug fluorescence as well as the protein fluorescence. LC-ESI-MS was used for the separation and characterization of underivatized oligosaccharide mixtures. With the limits of detection as low as 50 picograms, all individual components of oligosaccharide mixtures (up to 11 glucose-units long) were baseline resolved on a Cyclobond I 2000 column and detected using ESI-MS. This system is characterized by high chromatographic resolution, high column stability, and high sensitivity. In addition, this method showed potential usefulness for the sensitive and quick analysis of hydrolysis products of polysaccharides, and for trace level analysis of individual oligosaccharides or oligosaccharide isomers from biological systems.« less

  3. A new Ion Mobility Spectrometer

    NASA Astrophysics Data System (ADS)

    Butler, M. A.

    1998-03-01

    A new ion mobility spectrometer (IMS) concept has been demonstrated that traps ions in a potential well and then moves the well down a tube to a detector. The charge remaining in the well is measured as a function of well velocity or electric field that the ion experiences; thus separating the ions by mobility. The potential wave is generated and propagated down the tube by a series of ring electrodes along the tube under real-time computer control via an array of DACs. The operating characteristics of this device have been explored including the effects of ion "lifetime," well shape, and well velocity. The ion "lifetime" results from a radial field at the bottom of the potential well that pushes the ions toward the tube wall. This work was supported by the United States Department of Energy under Contract DE-AC04-94AL85000. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy.

  4. Velocity control propulsion subsystem of the Radio Astronomy Explorer satellite for Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Braught, W.; Moore, E. K.; Steinberg, R. L.

    1973-01-01

    The Velocity Control Propulsion Subsystem (VCPS) was designed the propulsion required for trajectory and lunar orbit corrections of the spacecraft. A GFE clamp assembly physically attaches the VCPS to the spacecraft and the unit is ejected after completing the required corrections. The VCPS is physically and functionally separated from the spacecraft except for the electrical and telemetry interfaces. A GFE transtage provides the superstructure on which the VCPS is assembled. The subsystem consists of two 5 foot pound rocket engine assemblies, 4 propellant tanks, 2 latching valves, 2 fill and drain valves, a system filter, pressure transducer, gas and propellant manifolds and electrical heaters and thermostats. The RAE-B VCPS program covered the design, manufacture and qualification of one subsystem. This subsystem was to be manufactured, subjected to qualification tests; and refurbished, if necessary, prior to flight. The VCPS design and test program precluded the need for refurbishing the subsystem and the unit was delivered to GSFC at the conclusion of the program.

  5. Texture variations suppress suprathreshold brightness and colour variations.

    PubMed

    Schofield, Andrew J; Kingdom, Frederick A A

    2014-01-01

    Discriminating material changes from illumination changes is a key function of early vision. Luminance cues are ambiguous in this regard, but can be disambiguated by co-incident changes in colour and texture. Thus, colour and texture are likely to be given greater prominence than luminance for object segmentation, and better segmentation should in turn produce stronger grouping. We sought to measure the relative strengths of combined luminance, colour and texture contrast using a suprathreshhold, psychophysical grouping task. Stimuli comprised diagonal grids of circular patches bordered by a thin black line and contained combinations of luminance decrements with either violet, red, or texture increments. There were two tasks. In the Separate task the different cues were presented separately in a two-interval design, and participants indicated which interval contained the stronger orientation structure. In the Combined task the cues were combined to produce competing orientation structure in a single image. Participants had to indicate which orientation, and therefore which cue was dominant. Thus we established the relative grouping strength of each cue pair presented separately, and compared this to their relative grouping strength when combined. In this way we observed suprathreshold interactions between cues and were able to assess cue dominance at ecologically relevant signal levels. Participants required significantly more luminance and colour compared to texture contrast in the Combined compared to Separate conditions (contrast ratios differed by about 0.1 log units), showing that suprathreshold texture dominates colour and luminance when the different cues are presented in combination.

  6. Effects of Frothers and Oil at Saltwater–Air Interfaces for Oil Separation: Molecular Dynamics Simulations and Experimental Measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chong, Leebyn; Lai, Yungchieh; Gray, McMahan

    Separating oil from saltwater is a process relevant to some industries and may be aided by bubble and froth generation. Simulating saltwater–air interfaces adsorbed with surfactants and oil molecules can assist in understanding froth stability to improve separation. Here, combining with surface tension experimental measurements, in this work we employ molecular dynamics with a united-atom force field to linear alkane oil and three surfactant frothers, methyl isobutyl carbinol (MIBC), terpineol, and ethyl glycol butyl ether (EGBE), to investigate their synergistic behaviors for oil separation. The interfacial phenomena were measured for a range of frother surface coverages on saltwater. Density profilesmore » of the hydrophilic and hydrophobic portions of the frothers show an expected orientation of alcohol groups adsorbing to the polar water. A decrease in surface tension with increasing surface coverage of MIBC and terpineol was observed and reflected in experiments where the frother concentration increased. Relations between surface coverage and bulk concentration were observed by comparing the surface tension decreases. Additionally, a range of oil surface coverages was explored when the interface has a thin layer of adsorbed frother molecules. Finally, the obtained results indicate that an increase in surface coverage of oil molecules led to an increase in surface tension for all frother types and the pair correlation functions depicted MIBC and terpineol as having higher distributions with water at closer distances than with oil.« less

  7. Effects of Frothers and Oil at Saltwater–Air Interfaces for Oil Separation: Molecular Dynamics Simulations and Experimental Measurements

    DOE PAGES

    Chong, Leebyn; Lai, Yungchieh; Gray, McMahan; ...

    2017-06-16

    Separating oil from saltwater is a process relevant to some industries and may be aided by bubble and froth generation. Simulating saltwater–air interfaces adsorbed with surfactants and oil molecules can assist in understanding froth stability to improve separation. Here, combining with surface tension experimental measurements, in this work we employ molecular dynamics with a united-atom force field to linear alkane oil and three surfactant frothers, methyl isobutyl carbinol (MIBC), terpineol, and ethyl glycol butyl ether (EGBE), to investigate their synergistic behaviors for oil separation. The interfacial phenomena were measured for a range of frother surface coverages on saltwater. Density profilesmore » of the hydrophilic and hydrophobic portions of the frothers show an expected orientation of alcohol groups adsorbing to the polar water. A decrease in surface tension with increasing surface coverage of MIBC and terpineol was observed and reflected in experiments where the frother concentration increased. Relations between surface coverage and bulk concentration were observed by comparing the surface tension decreases. Additionally, a range of oil surface coverages was explored when the interface has a thin layer of adsorbed frother molecules. Finally, the obtained results indicate that an increase in surface coverage of oil molecules led to an increase in surface tension for all frother types and the pair correlation functions depicted MIBC and terpineol as having higher distributions with water at closer distances than with oil.« less

  8. [Fear of child/family in pediatric intensive care units: what is the nurse's role?].

    PubMed

    Machado, Cidália; Sousa, Pedro Jácome

    2007-01-01

    The fear is considered a negative emotion, lived with apprehension, uncertainty and a sense of threat or danger to the personal integrity (Torres & Guerra, 2003). It is often associated with hospitalization of the chid/family, and may be the cause to start an emotional crisis due to the separation from environment and the usual routines, the loss of independence and autonomy, and also due to be with strange people (Bicho, 2006; Festas 1994; Freitas &Freitas, 2005; Hockenberry, 2006). Hospitalization in a Pediatric Intensive Care Unit (PICU) may worsen an already existing crisis not only for the given reasons but also because the child may be in life danger. The environment "aggressive"and stressant characteristic of these units also contributes to this situation. To minimize the fear and his negative effects, the nurse has an important role to play. Because of his/her activities and function he/she is the closest health care professional to the child/family, and therefore in a better position to establish a relationship of trust and empathy that will minimize such effects, as well as to the interventions best suited to achieve this objective.

  9. Coordination between leaf and stem traits related to leaf carbon gain and hydraulics across 32 drought-tolerant angiosperms.

    PubMed

    Ishida, Atsushi; Nakano, Takashi; Yazaki, Kenichi; Matsuki, Sawako; Koike, Nobuya; Lauenstein, Diego L; Shimizu, Michiru; Yamashita, Naoko

    2008-05-01

    We examined 15 traits in leaves and stems related to leaf C economy and water use for 32 co-existing angiosperms at ridge sites with shallow soil in the Bonin Islands. Across species, stem density was positively correlated to leaf mass per area (LMA), leaf lifespan (LLS), and total phenolics and condensed tannins per unit leaf N (N-based), and negatively correlated to leaf osmotic potential and saturated water content in leaves. LMA and LLS were negatively correlated to photosynthetic parameters, such as area-, mass-, and N-based assimilation rates. Although stem density and leaf osmotic potential were not associated with photosynthetic parameters, they were associated with some parameters of the leaf C economy, such as LMA and LLS. In the principal component (PCA) analysis, the first three axes accounted for 74.4% of total variation. Axis 1, which explained 41.8% of the total variation, was well associated with parameters for leaf C and N economy. Similarly, axis 2, which explained 22.3% of the total variation, was associated with parameters for water use. Axis 3, which explained 10.3% of the total variation, was associated with chemical defense within leaves. Axes 1 and 2 separated functional types relatively well, i.e., creeping trees, ruderal trees, other woody plants, C(3) shrubs and forbs, palms, and CAM plants, indicating that plant functional types were characterized by similar attributes of traits related to leaf C and N economy and water use. In addition, when the plot was extended by two unrelated traits, leaf mass-based assimilation rates and stem density, it also separated these functional types. These data indicate that differences in the functional types with contrasting plant strategies can be attributed to functional integration among leaf C economy, hydraulics, and leaf longevity, and that both leaf mass-based assimilation rates and stem density are key factors reflecting the different functions of plant species.

  10. Measuring New-Voter Learning via Three Channels of Political Information.

    ERIC Educational Resources Information Center

    Martinelli, Kathleen A.; Chaffee, Steven H.

    1995-01-01

    Reports on a cross-sectional survey of newly naturalized United States citizens before the 1988 United States presidential election. Finds that newspaper, television news, and television ads each made a separate, significant contribution to issue learning. (SR)

  11. U-Pb zircon age data for selected sedimentary, metasedimentary, and igneous rocks from northern and central Alaska

    USGS Publications Warehouse

    Moore, Thomas E.

    2014-01-01

    Data from two studies are included in this report. The first study, by Dumoulin and others (2013), reported the detrital zircon U-Pb age analysis of a single sample from the Upper Mississippian Ikalukrok unit of the Kuna Formation (table 1). The second study is that of Moore and others (in press), which focuses on the Upper Jurassic and Lower Cretaceous part of the Brookian sequence in the western Brooks Range (17 samples; table 2). For the latter study, samples were analyzed from the following units (1) the Upper Jurassic unit, Jw, of Curtis and others (1984), (2) the Lower Cretaceous Igrarok Hills unit of Moore and others (2002), (3) the Upper Jurassic and Lower Cretaceous Okpikruak Formation, (4) the Lower Cretaceous lower Brookian shale of Mull (1995), (5) the Lower Cretaceous Mount Kelly Graywacke Tongue of the Fortress Mountain Formation, (6) and the upper Lower Cretaceous Nanushuk Formation as redefined by Mull and others (2003). The results for each study are reported in separate Excel files, with individual samples in each study being shown as separate sheets within the files. The analyses of individual zircons are listed separately on the sheet according to the filtering schemes of the study and by the type of mass spectrometer used.

  12. 14 CFR 16.5 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Separation of functions. 16.5 Section 16.5... functions. (a) Proceedings under this part, including hearings under subpart F of this part, will be... prosecutorial functions in a proceeding under this part will not, in that case or a factually related case...

  13. ACER Physics Unit Tests: Unit Tests, Diagnostic Aids, [and] Teachers Handbook.

    ERIC Educational Resources Information Center

    Australian Council for Educational Research, Hawthorn.

    The Physics Unit Tests are designed to assist in the diagnostic evaluation of students' progress in the study of physics during the last two years of secondary schooling. They consist of a collection of 21 separate tests, each related to a different topic, and 21 diagnostic aids corresponding to the tests. The topics covered are: physical…

  14. The Danger of Poison. Level R = El Veneno es Peligroso. [Nivel R.

    ERIC Educational Resources Information Center

    Pennsylvania State Dept. of Education, Harrisburg.

    Designed by Project TEACH (Teaching Environmental Awareness to the Children of Harvest), the skill-sequenced curriculum unit was developed to teach 3- to 5-year-old migrant children about the benefits and possible hazards of pesticides. Prepared in both Spanish and English, the field-tested unit can be used as a separate teaching unit or…

  15. Engine Tune-Up Service. Unit 4: Secondary Circuit. Posttests. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Morse, David T.

    This book of posttests is designed to accompany the Engine Tune-Up Service Student Guide for Unit 4, Secondary Circuit, available separately as CE 031 214. Focus of the posttests is testing and servicing the secondary ignition circuit. One multiple choice posttest is provided that covers the seven performance objectives contained in the unit. (No…

  16. Engine Tune-Up Service. Unit 3: Primary Circuit. Posttests. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Morse, David T.

    This book of posttests is designed to accompany the Engine Tune-Up Service Student Guide for Unit 3, Primary Circuit, available separately as CE 031 211. Focus of the posttests is setting the primary ignition circuit. One multiple choice posttest is provided, covering the eight performance objectives contained in the unit. (No answer key is…

  17. Environmental Issues Conflict Unit. Teacher's Guide and Student Book.

    ERIC Educational Resources Information Center

    Fagerstrom, Richard A.; Borad, Bruce

    The two separate manuals focus on environmental issues of interest to secondary students. An introductory unit deals with basic ecology and is followed by another unit that explores man's ethic toward the use of environment. Emphasis is upon two major ecological conflicts: one over the use of a wilderness area, and the other over the use of living…

  18. An Evaluation of Two Methods for Teaching United States History to Students with Learning Disabilities

    ERIC Educational Resources Information Center

    Winchester, Katherine; Darch, Craig; Eaves, Ronald C.; Shippen, Margaret E.; Ern, Greg; Bell, Bedarius

    2009-01-01

    We compared two approaches to teaching United States history to students with learning disabilities (LD). We randomly assigned students in seventh through ninth grades (n = 44) to separate treatment groups (strategy-based instruction or traditional instruction). In both approaches, students were taught identical content on two units of the Civil…

  19. United States Marine Corps Personal Discount Rates: As Evidenced from Voluntary Separation Payment Programs

    DTIC Science & Technology

    2006-03-01

    1995. The Personal Discount Rate: Evidence from Air Force Loss Programs. Mankiw , N.G. 2004. Principles of Economics : Third Edition. Mason, OH...study also determined those personal, professional, and economic traits that had a significant influence on Marines during their separation payment...study also determined those personal, professional, and economic traits that had a significant influence on Marines during their separation payment

  20. Systematics of Rydberg Series of Diatomic Molecules and Correlation Diagrams

    NASA Astrophysics Data System (ADS)

    Lee, Chun-Woo

    2015-06-01

    Rydberg states are studied for H2, Li2, HeH, LiH and BeH using the multi-reference configuration interaction (MRCI) method. The systematics and regularities of the physical properties such as potential energies curves (PECs), quantum defect curves, permanent dipole moment and transition dipole moment curves of the Rydberg series are studied. They are explained using united atom perturbation theory by Bingel and Byers-Brown, Fermi model, Stark theory, and Mulliken's theory. Interesting mirror relationships of the dipole moments are observed between l-mixed Rydberg series, indicating that the members of the l-mixed Rydberg series have dipole moments with opposite directions, which are related to the reversal of the polarity of a dipole moment at the avoided crossing points. The assignment of highly excited states is difficult because of the usual absence of the knowledge on the behaviors of potential energy curves at small internuclear separation whereby the correlation between the united atom limit and separated atoms limit cannot be given. All electron MRCI calculations of PECs are performed to obtain the correlation diagrams between Rydberg orbitals at the united-atom and separated atoms limits.

  1. Minimum separation distances for natural gas pipeline and boilers in the 300 area, Hanford Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daling, P.M.; Graham, T.M.

    1997-08-01

    The U.S. Department of Energy (DOE) is proposing actions to reduce energy expenditures and improve energy system reliability at the 300 Area of the Hanford Site. These actions include replacing the centralized heating system with heating units for individual buildings or groups of buildings, constructing a new natural gas distribution system to provide a fuel source for many of these units, and constructing a central control building to operate and maintain the system. The individual heating units will include steam boilers that are to be housed in individual annex buildings located at some distance away from nearby 300 Area nuclearmore » facilities. This analysis develops the basis for siting the package boilers and natural gas distribution systems to be used to supply steam to 300 Area nuclear facilities. The effects of four potential fire and explosion scenarios involving the boiler and natural gas pipeline were quantified to determine minimum separation distances that would reduce the risks to nearby nuclear facilities. The resulting minimum separation distances are shown in Table ES.1.« less

  2. Separation of tartronic and glyceric acids by simulated moving bed chromatography.

    PubMed

    Coelho, Lucas C D; Filho, Nelson M L; Faria, Rui P V; Ferreira, Alexandre F P; Ribeiro, Ana M; Rodrigues, Alírio E

    2018-08-17

    The SMB unit developed by the Laboratory of Separation and Reaction Engineering (FlexSMB-LSRE ® ) was used to perform tartronic acid (TTA) and glyceric acid (GCA) separation and to validate the mathematical model in order to determine the optimum operating parameters of an industrial unit. The purity of the raffinate and extract streams in the experiments performed were 80% and 100%, respectively. The TTA and GCA productivities were 79 and 115 kg per liter of adsorbent per day, respectively and only 0.50 cubic meters of desorbent were required per kilogram of products. Under the optimum operating conditions, which were determined through an extensive simulation study based on the mathematical model developed to predict the performance of a real SMB unit, it was possible to achieve a productivity of 86 kg of TTA and 176 kg of GCA per cubic meter of adsorbent per day (considering the typical commercial purity value of 97% for both compounds) with an eluent consumption of 0.30 cubic meters per kilogram of products. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. Unitized Stiffened Composite Textile Panels: Manufacturing, Characterization, Experiments, and Analysis

    NASA Astrophysics Data System (ADS)

    Kosztowny, Cyrus Joseph Robert

    Use of carbon fiber textiles in complex manufacturing methods creates new implementations of structural components by increasing performance, lowering manufacturing costs, and making composites overall more attractive across industry. Advantages of textile composites include high area output, ease of handling during the manufacturing process, lower production costs per material used resulting from automation, and provide post-manufacturing assembly mainstreaming because significantly more complex geometries such as stiffened shell structures can be manufactured with fewer pieces. One significant challenge with using stiffened composite structures is stiffener separation under compression. Axial compression loading conditions have frequently observed catastrophic structural failure due to stiffeners separating from the shell skin. Characterizing stiffener separation behavior is often costly computationally and experimentally. The objectives of this research are to demonstrate unitized stiffened textile composite panels can be manufactured to produce quality test specimens, that existing characterization techniques applied to state-of-the-art high-performance composites provide valuable information in modeling such structures, that the unitized structure concept successfully removes stiffener separation as a primary structural failure mode, and that modeling textile material failure modes are sufficient to accurately capture postbuckling and final failure responses of the stiffened structures. The stiffened panels in this study have taken the integrally stiffened concept to an extent such that the stiffeners and skin are manufactured at the same time, as one single piece, and from the same composite textile layers. Stiffener separation is shown to be removed as a primary structural failure mode for unitized stiffened composite textile panels loaded under axial compression well into the postbuckling regime. Instead of stiffener separation, a material damaging and failure model effectively captures local post-peak material response via incorporating a mesoscale model using a multiscaling framework with a smeared crack element-based failure model in the macroscale stiffened panel. Material damage behavior is characterized by simple experimental tests and incorporated into the post-peak stiffness degradation law in the smeared crack implementation. Computational modeling results are in overall excellent agreement compared to the experimental responses.

  4. Function Allocation between Automation and Human Pilot for Airborne Separation Assurance

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Enea, Gabriele; Lewis, TImothy A.

    2016-01-01

    Maintaining safe separation between aircraft is a key determinant of the airspace capacity to handle air transportation. With the advent of satellite-based surveillance, aircraft equipped with the needed technologies are now capable of maintaining awareness of their location in the airspace and sharing it with their surrounding traffic. As a result, concepts and cockpit automation are emerging to enable delegating the responsibility of maintaining safe separation from traffic to the pilot; thus increasing the airspace capacity by alleviating the limitation of the current non-scalable centralized ground-based system. In this paper, an analysis of allocating separation assurance functions to the human pilot and cockpit automation is presented to support the design of these concepts and technologies. A task analysis was conducted with the help of Petri nets to identify the main separation assurance functions and their interactions. Each function was characterized by three behavior levels that may be needed to perform the task: skill, rule and knowledge based levels. Then recommendations are made for allocating each function to an automation scale based on their behavior level characterization and with the help of Subject matter experts.

  5. Processing of the major autolysin of E. faecalis, AtlA, by the zinc-metalloprotease, GelE, impacts AtlA septal localization and cell separation.

    PubMed

    Stinemetz, Emily K; Gao, Peng; Pinkston, Kenneth L; Montealegre, Maria Camila; Murray, Barbara E; Harvey, Barrett R

    2017-01-01

    AtlA is the major peptidoglycan hydrolase of Enterococcus faecalis involved in cell division and cellular autolysis. The secreted zinc metalloprotease, gelatinase (GelE), has been identified as an important regulator of cellular function through post-translational modification of protein substrates. AtlA is a known target of GelE, and their interplay has been proposed to regulate AtlA function. To study the protease-mediated post-translational modification of AtlA, monoclonal antibodies were developed as research tools. Flow cytometry and Western blot analysis suggests that in the presence of GelE, surface-bound AtlA exists primarily as a N-terminally truncated form whereas in the absence of GelE, the N-terminal domain of AtlA is retained. We identified the primary GelE cleavage site occurring near the transition between the T/E rich Domain I and catalytic region, Domain II via N-terminal sequencing. Truncation of AtlA had no effect on the peptidoglycan hydrolysis activity of AtlA. However, we observed that N-terminal cleavage was required for efficient AtlA-mediated cell division while unprocessed AtlA was unable to resolve dividing cells into individual units. Furthermore, we observed that the processed AtlA has the propensity to localize to the cell septum on wild-type cells whereas unprocessed AtlA in the ΔgelE strain were dispersed over the cell surface. Combined, these results suggest that AtlA septum localization and subsequent cell separation can be modulated by a single GelE-mediated N-terminal cleavage event, providing new insights into the post-translation modification of AtlA and the mechanisms governing chaining and cell separation.

  6. Processing of the major autolysin of E. faecalis, AtlA, by the zinc-metalloprotease, GelE, impacts AtlA septal localization and cell separation

    PubMed Central

    Pinkston, Kenneth L.; Montealegre, Maria Camila; Murray, Barbara E.

    2017-01-01

    AtlA is the major peptidoglycan hydrolase of Enterococcus faecalis involved in cell division and cellular autolysis. The secreted zinc metalloprotease, gelatinase (GelE), has been identified as an important regulator of cellular function through post-translational modification of protein substrates. AtlA is a known target of GelE, and their interplay has been proposed to regulate AtlA function. To study the protease-mediated post-translational modification of AtlA, monoclonal antibodies were developed as research tools. Flow cytometry and Western blot analysis suggests that in the presence of GelE, surface-bound AtlA exists primarily as a N-terminally truncated form whereas in the absence of GelE, the N-terminal domain of AtlA is retained. We identified the primary GelE cleavage site occurring near the transition between the T/E rich Domain I and catalytic region, Domain II via N-terminal sequencing. Truncation of AtlA had no effect on the peptidoglycan hydrolysis activity of AtlA. However, we observed that N-terminal cleavage was required for efficient AtlA-mediated cell division while unprocessed AtlA was unable to resolve dividing cells into individual units. Furthermore, we observed that the processed AtlA has the propensity to localize to the cell septum on wild-type cells whereas unprocessed AtlA in the ΔgelE strain were dispersed over the cell surface. Combined, these results suggest that AtlA septum localization and subsequent cell separation can be modulated by a single GelE-mediated N-terminal cleavage event, providing new insights into the post-translation modification of AtlA and the mechanisms governing chaining and cell separation. PMID:29049345

  7. A Reverse Osmosis System for an Advanced Separation Process Laboratory.

    ERIC Educational Resources Information Center

    Slater, C. S.; Paccione, J. D.

    1987-01-01

    Focuses on the development of a pilot unit for use in an advanced separations process laboratory in an effort to develop experiments on such processes as reverse osmosis, ultrafiltration, adsorption, and chromatography. Discusses reverse osmosis principles, the experimental system design, and some experimental studies. (TW)

  8. Description and key to larvae of Curculio spp. of eastern United States and Canada (coleoptera: Curculionidae)

    Treesearch

    Lester P. Gibson

    1985-01-01

    A general description of Curculio larvae is given. Ke y characters are presented to separate 15 of the 16 described species of eastern North America. A brief key for separating Curculio larvae from Conotrachelus and lepidopterous larvae is presented.

  9. 24 CFR 180.220 - Separation of functions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND BUSINESS OPPORTUNITY CONSOLIDATED HUD HEARING PROCEDURES FOR CIVIL RIGHTS MATTERS Administrative Law Judge § 180.220 Separation of functions. No officer, employee, or agent of the Federal Government...

  10. Nursing diagnoses in patients having mechanical ventilation support in a respiratory intensive care unit in Turkey.

    PubMed

    Yücel, Şebnem Çinar; Eşer, Ismet; Güler, Elem Kocaçal; Khorshid, Leyla

    2011-10-01

    This research was carried out to find out the nursing diagnoses in patients who have mechanical ventilation support in a respiratory intensive care unit. The study was conducted with 51 evaluations of critically ill adult patients who underwent invasive and non-invasive mechanical ventilation therapy in 2008. Data collection was based on Gordon's 11 Functional Health Patterns, and nursing diagnoses were determined according to North American Nursing Diagnosis Association-International (NANDA-I) Taxonomy II. The nursing diagnoses were determined by two researchers separately. The consistency between the nursing diagnoses defined by the two researchers was evaluated by using Cohen's kappa (κ). Forty men (78.4%) and 11 women (21.6%) whose mean ages were 70.19 (SD = 8.96) years were included in the study. Nineteen subgroups of nursing diagnoses about safety/protection domain, and 15 subgroups about activity/rest domain were seen at different rates in the patients. There was a statistically significant difference between mechanical ventilation via tracheostomy or endotracheal tube and decreased cardiac output (d.f. = 1, χ(2) = 4.760, P = 0.029). The relationship between the length of time under mechanical ventilation and impaired physical mobility was considerably significant (d.f. = 3, χ(2) = 24.459, P = 0.000). It was found out that there was a high degree of agreement (96.8%) between the nursing diagnoses defined by the two researchers separately (κ = 0.936, SE = 0.08). © 2011 Blackwell Publishing Asia Pty Ltd.

  11. On the Physics of Flow Separation Along a Low Pressure Turbine Blade Under Unsteady Flow Conditions

    NASA Technical Reports Server (NTRS)

    Schobeiri, Meinhard T.; Ozturk, Burak; Ashpis, David E.

    2005-01-01

    The present study, which is the first of a series of investigations dealing with specific issues of low pressure turbine (LPT) boundary layer aerodynamics, is aimed at providing detailed unsteady boundary flow information to understand the underlying physics of the inception, onset, and extent of the separation zone. A detailed experimental study on the behavior of the separation zone on the suction surface of a highly loaded LPT-blade under periodic unsteady wake flow is presented. Experimental investigations were performed at Texas A&M Turbomachinery Performance and Flow Research Laboratory using a large-scale unsteady turbine cascade research facility with an integrated wake generator and test section unit. To account for a high flow deflection of LPT-cascades at design and off-design operating points, the entire wake generator and test section unit including the traversing system is designed to allow a precise angle adjustment of the cascade relative to the incoming flow. This is done by a hydraulic platform, which simultaneously lifts and rotates the wake generator and test section unit. The unit is then attached to the tunnel exit nozzle with an angular accuracy of better than 0.05 , which is measured electronically. Utilizing a Reynolds number of 110,000 based on the blade suction surface length and the exit velocity, one steady and two different unsteady inlet flow conditions with the corresponding passing frequencies, wake velocities and turbulence intensities are investigated using hot-wire anemometry. In addition to the unsteady boundary layer measurements, blade surface pressure measurements were performed at Re=50,000, 75,000, 100,000, and 125,000 at one steady and two periodic unsteady inlet flow conditions. Detailed unsteady boundary layer measurement identifies the onset and extent of the separation zone as well as its behavior under unsteady wake flow. The results presented in ensemble-averaged and contour plot forms contribute to understanding the physics of the separation phenomenon under periodic unsteady wake flow. Several physical mechanisms are discussed.

  12. On the Physics of Flow Separation Along a Low Pressure Turbine Blade Under Unsteady Flow Conditions

    NASA Technical Reports Server (NTRS)

    Schobeiri, Meinhard T.; Ozturk, Burak; Ashpis, David E.

    2003-01-01

    The present study, which is the first of a series of investigations dealing with specific issues of low pressure turbine (LPT) boundary layer aerodynamics, is aimed at providing detailed unsteady boundary flow information to understand the underlying physics of the inception, onset, and extent of the separation zone. A detailed experimental study on the behavior of the separation zone on the suction surface of a highly loaded LPT-blade under periodic unsteady wake flow is presented. Experimental investigations were performed at Texas A&M Turbomachinery Performance and Flow Research Laboratory using a large-scale unsteady turbine cascade research facility with an integrated wake generator and test section unit. To account for a high flow deflection of LPT-cascades at design and off-design operating points, the entire wake generator and test section unit including the traversing system is designed to allow a precise angle adjustment of the cascade relative to the incoming flow. This is done by a hydraulic platform, which simultaneously lifts and rotates the wake generator and test section unit. The unit is then attached to the tunnel exit nozzle with an angular accuracy of better than 0.05 , which is measured electronically. Utilizing a Reynolds number of 110,000 based on the blade suction surface length and the exit velocity, one steady and two different unsteady inlet flowconditions with the corresponding passing frequencies, wake velocities and turbulence intensities are investigated using hot-wire anemometry. In addition to the unsteady boundary layer measurements, blade surface pressure measurements were performed at Re=50,000, 75,000, 100,000, and 125,000 at one steady and two periodic unsteady inlet flow conditions. Detailed unsteady boundary layer measurement identifies the onset and extent of the separation zone as well as its behavior under unsteady wake flow. The results presented in ensemble-averaged and contour plot forms contribute to understanding the physics of the separation phenomenon under periodic unsteady wake flow. Several physical mechanisms are discussed.

  13. Dual Functions of Perirhinal Cortex in Fear Conditioning

    PubMed Central

    Kent, Brianne A.; Brown, Thomas H.

    2012-01-01

    The present review examines the role of perirhinal cortex (PRC) in Pavlovian fear conditioning. The focus is on rats, partly because so much is known, behaviorally and neurobiologically, about fear conditioning in these animals. In addition, the neuroanatomy and neurophysiology of rat PRC have been described in considerable detail at the cellular and systems levels. The evidence suggests that PRC can serve at least two types of mnemonic functions in Pavlovian fear conditioning. The first function, termed "stimulus unitization," refers to the ability to treat two or more separate items or stimulus elements as a single entity. Supporting evidence for this perceptual function comes from studies of context conditioning as well as delay conditioning to discontinuous auditory cues. In a delay paradigm, the conditional stimulus (CS) and unconditional stimulus (US) overlap temporally and co-terminate. The second PRC function entails a type of "transient memory." Supporting evidence comes from studies of trace cue conditioning, where there is a temporal gap or trace interval between the CS offset and the US onset. For learning to occur, there must be a transient CS representation during the trace interval. We advance a novel neurophysiological mechanism for this transient representation. These two hypothesized functions of PRC are consistent with inferences based on non-aversive forms of learning. PMID:22903623

  14. Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment.

    PubMed

    Löwe, Bernd; Spitzer, Robert L; Williams, Janet B W; Mussell, Monika; Schellberg, Dieter; Kroenke, Kurt

    2008-01-01

    To determine diagnostic overlap of depression, anxiety and somatization as well as their unique and overlapping contribution to functional impairment. Two thousand ninety-one consecutive primary care clinic patients participated in a multicenter cross-sectional survey in 15 primary care clinics in the United States (participation rate, 92%). Depression, anxiety, somatization and functional impairment were assessed using validated scales from the Patient Health Questionnaire (PHQ) (PHQ-8, eight-item depression module; GAD-7, seven-item Generalized Anxiety Disorder Scale; and PHQ-15, 15-item somatic symptom scale) and the Short-Form General Health Survey (SF-20). Multiple linear regression analyses were used to investigate unique and overlapping associations of depression, anxiety and somatization with functional impairment. In over 50% of cases, comorbidities existed between depression, anxiety and somatization. The contribution of the commonalities of depression, anxiety and somatization to functional impairment substantially exceeded the contribution of their independent parts. Nevertheless, depression, anxiety and somatization did have important and individual effects (i.e., separate from their overlap effect) on certain areas of functional impairment. Given the large syndrome overlap, a potential consideration for future diagnostic classification would be to describe basic diagnostic criteria for a single overarching disorder and to optionally code additional diagnostic features that allow a more detailed classification into specific depressive, anxiety and somatoform subtypes.

  15. Evaluation of renal function in patients with a main renal stone larger than 1 cm and perioperative renal functional change in minimally invasive renal stone surgery: a prospective, observational study.

    PubMed

    Piao, Songzhe; Park, Juhyun; Son, Hwancheol; Jeong, Hyeon; Cho, Sung Yong

    2016-05-01

    To compare the perioperative relative renal function and determine predictors of deterioration and recovery of separate renal function in patients with renal stones >10 mm and who underwent mini-percutaneous nephrolithotomy or retrograde intra-renal surgery. A main stone >10 mm or stones growing, high-risk stone formers and extracorporeal shock-wave lithotripsy-resistant stones were prospectively included in 148 patients. Patients with bilateral renal stones and anatomical deformities were excluded. Renal function was evaluated by estimated glomerular filtration rate, 99m-technetium dimercaptosuccinic acid and 99m-technetium diethylenetriamine pentaacetate prior to intervention and at postoperative 3 months. Logistic regression analyses were performed to find predictors of functional deterioration and recovery. The overall stone-free rate was 85.1 %. A third of patients (53/148, 35.8 %) with renal stones >10 mm showed deterioration of separate renal function. Mean renal function of operative sites showed 58.2 % (36.8 %/63.2 %) of that of contralateral sites in these patients. Abnormal separate renal function showed postoperative recovery in 31 patients (58.5 %). Three cases (5.7 %) showed deterioration of separate renal function despite no presence of remnant stones. Improvement rates of the abnormal separate renal function did not differ according to the type of surgery. The presence of hydronephrosis and three or more stones were significant predictors for renal function deterioration. Female gender and three or more stones were significantly correlated with postoperative recovery. Mini-percutaneous nephrolithotomy or retrograde intra-renal surgery was effective and safe for renal function preservation. Patients with multiple large stones should be considered for candidates of active surgical removal.

  16. Flotation machine and process for removing impurities from coals

    DOEpatents

    Szymocha, K.; Ignasiak, B.; Pawlak, W.; Kulik, C.; Lebowitz, H.E.

    1995-12-05

    The present invention is directed to a type of flotation machine that combines three separate operations in a single unit. The flotation machine is a hydraulic separator that is capable of reducing the pyrite and other mineral matter content of a coal. When the hydraulic separator is used with a flotation system, the pyrite and certain other mineral particles that may have been entrained by hydrodynamic forces associated with conventional flotation machines and/or by the attachment forces associated with the formation of microagglomerates are washed and separated from the coal. 4 figs.

  17. Flotation machine and process for removing impurities from coals

    DOEpatents

    Szymocha, Kazimierz; Ignasiak, Boleslaw; Pawlak, Wanda; Kulik, Conrad; Lebowitz, Howard E.

    1995-01-01

    The present invention is directed to a type of flotation machine that combines three separate operations in a single unit. The flotation machine is a hydraulic separator that is capable of reducing the pyrite and other mineral matter content of a coal. When the hydraulic separator is used with a flotation system, the pyrite and certain other minerals particles that may have been entrained by hydrodynamic forces associated with conventional flotation machines and/or by the attachment forces associated with the formation of microagglomerates are washed and separated from the coal.

  18. Flotation machine and process for removing impurities from coals

    DOEpatents

    Szymocha, K.; Ignasiak, B.; Pawlak, W.; Kulik, C.; Lebowitz, H.E.

    1997-02-11

    The present invention is directed to a type of flotation machine that combines three separate operations in a single unit. The flotation machine is a hydraulic separator that is capable of reducing the pyrite and other mineral matter content of a coal. When the hydraulic separator is used with a flotation system, the pyrite and certain other minerals particles that may have been entrained by hydrodynamic forces associated with conventional flotation machines and/or by the attachment forces associated with the formation of microagglomerates are washed and separated from the coal. 4 figs.

  19. Flotation machine and process for removing impurities from coals

    DOEpatents

    Szymocha, Kazimierz; Ignasiak, Boleslaw; Pawlak, Wanda; Kulik, Conrad; Lebowitz, Howard E.

    1997-01-01

    The present invention is directed to a type of flotation machine that combines three separate operations in a single unit. The flotation machine is a hydraulic separator that is capable of reducing the pyrite and other mineral matter content of a coal. When the hydraulic separator is used with a flotation system, the pyrite and certain other minerals particles that may have been entrained by hydrodynamic forces associated with conventional flotation machines and/or by the attachment forces associated with the formation of microagglomerates are washed and separated from the coal.

  20. High-contrast imaging with the JWST-NIRSpec Integral Field Unit

    NASA Astrophysics Data System (ADS)

    Ygouf, M.; Beichman, C.; Hodapp, K.; Roellig, T.

    2017-12-01

    With its integral field unit, the near-infrared spectrograph NIRSPEC on JWST will allow to measure high-resolution spectra into the 3-\\SI{5}μm range with an increased sensitivity over ground-based systems. This capability will considerably extend our knowledge of brown dwarfs and bright exoplanets at large separations from their host star. But because there is not any coronagraph on NIRSPEC, the performance in term of contrast at close separation will be extremely limited. In this communication, we explore possibilities to further push this limitation by exploiting the wavelength diversity offered by the spectral differential imaging strategy.

  1. Perturbed invariant subspaces and approximate generalized functional variable separation solution for nonlinear diffusion-convection equations with weak source

    NASA Astrophysics Data System (ADS)

    Xia, Ya-Rong; Zhang, Shun-Li; Xin, Xiang-Peng

    2018-03-01

    In this paper, we propose the concept of the perturbed invariant subspaces (PISs), and study the approximate generalized functional variable separation solution for the nonlinear diffusion-convection equation with weak source by the approximate generalized conditional symmetries (AGCSs) related to the PISs. Complete classification of the perturbed equations which admit the approximate generalized functional separable solutions (AGFSSs) is obtained. As a consequence, some AGFSSs to the resulting equations are explicitly constructed by way of examples.

  2. High pressure effects in high-field asymmetric waveform ion mobility spectrometry.

    PubMed

    Wang, Yonghuan; Wang, Xiaozhi; Li, Lingfen; Chen, Chilai; Xu, Tianbai; Wang, Tao; Luo, Jikui

    2016-08-30

    High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) is an analytical technique based on the principle of non-linear electric field dependence of coefficient of mobility of ions for separation that was originally conceived in the Soviet Union in the early 1980s. Being well developed over the past decades, FAIMS has become an efficient method for the separation and characterization of gas-phase ions at ambient pressure, often in air, to detect trace amounts of chemical species including explosives, toxic chemicals, chemical warfare agents and other compounds. However the resolution of FAIMS and ion separation capability need to be improved for more applications of the technique. The effects of above-ambient pressure varying from 1 to 3 atm on peak position, resolving power, peak width, and peak intensity are investigated theoretically and experimentally using micro-fabricated planar FAIMS in purified air. Peak positions, varying with pressure in a way as a function of dispersion voltage, could be simplified by expressing both compensation and dispersion fields in Townsend units for E/N, the ratio of electric field intensity (E) to the gas number density (N). It is demonstrated that ion Townsend-scale peak positions remain unchanged for a range of pressures investigated, implying that the higher the pressure is, stronger compensation and separation fields are needed within limits of air breakdown field. Increase in pressure is found to separate ions that could not be distinguished in ambient pressure, which could be interpreted as the differentials of ions' peak compensation voltage expanded wider than the dilation of peak widths leading to resolving power enhancement with pressure. Increase in pressure can also result in an increase in peak intensity. Copyright © 2016 John Wiley & Sons, Ltd.

  3. An audit improves the quality of water within the dental unit water lines of three separate facilities of a United Kingdom NHS Trust.

    PubMed

    Chate, R A C

    2006-11-11

    To improve the quality of water emanating from dental unit waterlines (DUWLs). A prospective clinical audit. Three geographically separate district dental facilities of a United Kingdom NHS Trust, involving two community clinics and one hospital orthodontic department, which were evaluated between 2002 and 2004. Samples of water discharged from the DUWLs were collected prior to the start and midway through a morning session. These were tested microbiologically at a United Kingdom Accreditation Service testing laboratory within six hours of sampling. One of the clinics followed the contemporaneous BDA advice of flushing water through its DUWLs while the other two clinics used separate intermittent disinfection purging regimes instead. One of them used a two stage protocol of Ethylene Diamine Tetra-Acetic acid followed by hydrogen peroxide, while the other used Bio 2000 as a single agent, which was subsequently superseded by the continuous use of super-oxidised water (Sterilox). To assess whether the samples either met the American Dental Association's guideline on the quality of DUWL water, or the more stringent European Union standards for potable (drinking) water. The two units which used a disinfection regime both complied with the ADA guideline and the EU potable water standard. However, the unit which only flushed through its DUWLs without using a disinfectant failed to comply with either of them. After all three dental facilities subsequently standardised their DUWL disinfection regimes by using Bio 2000, the colony counts from all of the water samples thereafter remained well below the EU recommended level. The unit which progressed to using Sterilox as a continuous disinfectant achieved and maintained zero readings from its water samples. Clinical audit can result in the improvement of the quality of water that is discharged through DUWLs, thereby minimising both the risk of cross infection to vulnerable patients, as well as to dental staff chronically exposed to contaminated aerosols.

  4. Regional geohydrology of the northern Louisiana salt-dome basin; Part II, Geohydrologic maps of the Tertiary aquifers and related confining layers

    USGS Publications Warehouse

    Ryals, G.N.

    1984-01-01

    Regional geohydrologic maps show the altitude of the base and the thickness of the aquifers of Tertiary age and related confining layers in the northern Louisiana salt-dome basin. The limit of freshwater in aquifers is also shown. The basin has an area of about 3,000 square miles, and four geologic units of Tertiary age contain regional aquifers. From oldest (deepest) to youngest, the aquifers are in the Wilcox Group, Carrizo Sand, Sparta Sand, and Cockfield Formation. As the Wilcox is hydraulically interconnected with the overlying Carrizo, they are treated as one hydrologic unit, the Wilcox-Carrizo aquifer. The aquifers are separated by confining layers that retard water movement. In the northwestern part of the area, the Wilcox-Carrizo aquifer is separated from the underlying sand facies of the Nacatoch Sand (Cretaceous age) by a confining layer composed of the Midway Group (Tertiary age) and the underlying Arkadelphia Marl and an upper clay and marl facies of the Nacatoch Sand (both of Cretaceous age). In the remainder of the area, the Wilcox-Carrizo aquifer is separated from an underlying Cretaceous aquifer comprised of the Tokio Formation and Brownstown Marl by the Midway Group and several underlying Cretaceous units which in order of increasing age are the Arkadelphia Maril, Nacatoch Sand, Saratoga Chalk, Marlbrook Marl , and Annona Chalk. The Wilcox-Carrizo aquifer is separated from the Sparta aquifer by the overyling Cane River Formation. The Sparta aquifer is separated from the Cockfield aquifer by the overlying Cook Mountain Formation. (USGS)

  5. Magnetic properties of the Bled El Hadba phosphate-bearing formation (Djebel Onk, Algeria): Consequences of the enrichment of the phosphate ore deposit

    NASA Astrophysics Data System (ADS)

    Bezzi, Nacer; Aïfa, Tahar; Merabet, Djoudi; Pivan, Jean-Yves

    2008-02-01

    To improve the enrichment of the Thanetian marine phosphate ore deposit from the quarry of Bled El Hadba (Djebel Onk, Algeria) before its exploitation, we first conducted a joint study using different techniques for comparison. These studies reveal that magnetic minerals play a significant role within the matrix of the central productive unit which is squeezed between two other units. Magnetic separation procedures show that there are some positive correlations between magnetic susceptibility and grain size fraction (80-250 μm). These dolomite-rich fractions are more clearly separated. Different tools were used to characterize the magnetic minerals (X-ray, microprobe, differential scanning calorimetry, thermogravimetric and thermomagnetic analyses). They show correlations between magnetic phases and the presence of associated magnetic minerals within the matrix or included in the phosphate ore deposit. They enabled us to distinguish a series of magnetic minerals (magnetite, hematite, maghemite, goethite, ilmenite, pyrite, iron-titanium oxide and titanium oxide sulphate) and to determine that Fe and Ti are prevalent in the separated fractions, following the same variation as Mg. The phosphorous (phosphate) rate is higher in the non-magnetic material, especially in the layers that are rich in dolomitic carbonates (upper and lower units), which could be trapped within the dolomitic matrix, while Magnesium (dolomite) is more important in the magnetic fraction. The separation of phosphate elements and dolomite carbonates is effective and therefore the ore can be enriched through magnetic procedures. Comparison between products enriched by magnetic separation, flotation and calcination showed important differences, chemically, economically and technically speaking.

  6. Airborne Tactical Intent-Based Conflict Resolution Capability

    NASA Technical Reports Server (NTRS)

    Wing, David J.; Vivona, Robert A.; Roscoe, David A.

    2009-01-01

    Trajectory-based operations with self-separation involve the aircraft taking the primary role in the management of its own trajectory in the presence of other traffic. In this role, the flight crew assumes the responsibility for ensuring that the aircraft remains separated from all other aircraft by at least a minimum separation standard. These operations are enabled by cooperative airborne surveillance and by airborne automation systems that provide essential monitoring and decision support functions for the flight crew. An airborne automation system developed and used by NASA for research investigations of required functionality is the Autonomous Operations Planner. It supports the flight crew in managing their trajectory when responsible for self-separation by providing monitoring and decision support functions for both strategic and tactical flight modes. The paper focuses on the latter of these modes by describing a capability for tactical intent-based conflict resolution and its role in a comprehensive suite of automation functions supporting trajectory-based operations with self-separation.

  7. Standardized Full-Field Electroretinography in the Green Monkey (Chlorocebus sabaeus)

    PubMed Central

    Bouskila, Joseph; Javadi, Pasha; Palmour, Roberta M.; Bouchard, Jean-François; Ptito, Maurice

    2014-01-01

    Abstract Full-field electroretinography is an objective measure of retinal function, serving as an important diagnostic clinical tool in ophthalmology for evaluating the integrity of the retina. Given the similarity between the anatomy and physiology of the human and Green Monkey eyes, this species has increasingly become a favorable non-human primate model for assessing ocular defects in humans. To test this model, we obtained full-field electroretinographic recordings (ERG) and normal values for standard responses required by the International Society for Clinical Electrophysiology of Vision (ISCEV). Photopic and scotopic ERG recordings were obtained by full-field stimulation over a range of 6 log units of intensity in dark-adapted or light-adapted eyes of adult Green Monkeys (Chlorocebus sabaeus). Intensity, duration, and interval of light stimuli were varied separately. Reproducible values of amplitude and latency were obtained for the a- and b-waves, under well-controlled adaptation and stimulus conditions; the i-wave was also easily identifiable and separated from the a-b-wave complex in the photopic ERG. The recordings obtained in the healthy Green Monkey matched very well with those in humans and other non-human primate species (Macaca mulatta and Macaca fascicularis). These results validate the Green Monkey as an excellent non-human primate model, with potential to serve for testing retinal function following various manipulations such as visual deprivation or drug evaluation. PMID:25360686

  8. Dimensions of care for dementia sufferers in long-term care institutions: are they related to outcomes?

    PubMed

    Chappell, N L; Reid, R C

    2000-07-01

    This study empirically examined whether dimensions of care cluster in special care units (SCUs) compared with non-SCUs. The relationship between SCU status plus separate measures of the dimensions of care and outcomes for dementia sufferers was then investigated. Data were drawn from the Intermediate Care Facility Project. The sample (N = 510) included residents with dementia, aged 65 and older, in intermediate care facilities throughout the province of British Columbia. Canada. Longitudinal data included 6 outcomes: cognitive function, behavioral problems of agitation and social skills, physical functioning, and quality of life measured through affect and expressive language skills. Separate multiple linear regression equations were estimated, relating each of these outcomes to 5 dimensions of care: preadmission and admission procedures. staff training and education, nonuse of physical and chemical restraints, flexible care routines and resident-relevant activities, and the environment. The results showed there is virtually no clustering of dimensions along SCU/non-SCU lines. Neither SCU status nor the individual dimensions were highly predictive of outcomes. Residents' affect at t1 emerged as a characteristic that was significantly correlated with other outcomes. This Canadian research can be added to the few but growing number of rigorous studies that suggest SCUs are not homogeneous and do not necessarily provide better care than non-SCUs. Moreover, it raises questions about the benefits of "best practice" dimensions of care, regardless of SCU status.

  9. 40 CFR 61.131 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... circulation tank means any vessel that functions to store or contain flushing liquor that is separated from... that functions to condense benzene-containing vapors. Light-oil decanter means any vessel, tank, or other type of device in the light-oil recovery operation that functions to separate light oil from water...

  10. 40 CFR 61.131 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... circulation tank means any vessel that functions to store or contain flushing liquor that is separated from... that functions to condense benzene-containing vapors. Light-oil decanter means any vessel, tank, or other type of device in the light-oil recovery operation that functions to separate light oil from water...

  11. 40 CFR 61.131 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... circulation tank means any vessel that functions to store or contain flushing liquor that is separated from... that functions to condense benzene-containing vapors. Light-oil decanter means any vessel, tank, or other type of device in the light-oil recovery operation that functions to separate light oil from water...

  12. A Piezoelectric Passive Wireless Sensor for Monitoring Strain

    NASA Technical Reports Server (NTRS)

    Zou, Xiyue; Ferri, Paul N.; Hogan, Ben; Mazzeo, Aaron D.; Hull. Patrick V.

    2017-01-01

    Interest in passive wireless sensing has grown over the past few decades to meet demands in structural health monitoring.(Deivasigamani et al., 2013; Wilson and Juarez, 2014) This work describes a passive wireless sensor for monitoring strain, which does not have an embedded battery or chip. Without an embedded battery, the passive wireless sensor has the potential to maintain its functionality over long periods in remote/harsh environments. This work also focuses on monitoring small strain (less than 1000 micro-?). The wireless sensing system includes a reader unit, a coil-like transponder, and a sensing unit. It operates in the Megahertz (MHz) frequency range, which allows for a few centimeters of separation between the reader and sensing unit during measurements. The sensing unit is a strain-sensitive piezoelectric resonator that maximizes the energy efficiency at the resonance frequency, so it converts nanoscale mechanical variations to detectable differences in electrical signal. In response to an external loading, the piezoelectric sensor breaks from its original electromechanical equilibrium, and the resonant frequency shifts as the system reaches a new balanced equilibrium. In this work, the fixture of the sensing unit is a small, sticker-like package that converts the surface strain of a test material to measurable shifts in resonant frequencies. Furthermore, electromechanical modeling provides a lumped-parameter model of the system to describe and predict the measured wireless signals of the sensor. Detailed characterization demonstrates how this wireless sensor has resolution comparable to that of conventional wired strain sensors for monitoring small strain.

  13. Advanced Separators for Lithium-Ion and Lithium-Sulfur Batteries: A Review of Recent Progress.

    PubMed

    Xiang, Yinyu; Li, Junsheng; Lei, Jiaheng; Liu, Dan; Xie, Zhizhong; Qu, Deyu; Li, Ke; Deng, Tengfei; Tang, Haolin

    2016-11-09

    Li-ion and Li-S batteries find enormous applications in different fields, such as electric vehicles and portable electronics. A separator is an indispensable part of the battery design, which functions as a physical barrier for the electrode as well as an electrolyte reservoir for ionic transport. The properties of the separators directly influence the performance of the batteries. Traditional polyolefin separators showed low thermal stability, poor wettability toward the electrolyte, and inadequate barrier properties to polysulfides. To improve the performance and durability of Li-ion and Li-S batteries, development of advanced separators is required. In this review, we summarize recent progress on the fabrication and application of novel separators, including the functionalized polyolefin separator, polymeric separator, and ceramic separator, for Li-ion and Li-S batteries. The characteristics, advantages, and limitations of these separators are discussed. A brief outlook for the future directions of the research in the separators is also provided. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Pressure flaking to serrate bifacial points for the hunt during the MIS5 at Sibudu Cave (South Africa)

    PubMed Central

    Lentfer, Carol; Schmid, Viola C.; Porraz, Guillaume; Conard, Nicholas J.

    2017-01-01

    Projectile technology is considered to appear early in the southern African Middle Stone Age (MSA) and the rich and high resolution MSA sequence of Sibudu Cave in KwaZulu-Natal has provided many new insights about the use and hafting of various projectile forms. We present the results of a functional and technological analysis on a series of unpublished serrated bifacial points recently recovered from the basal deposits of Sibudu Cave. These serrated tools, which only find equivalents in the neighbouring site of Umhlatuzana, precede the Still Bay techno-complex and are older than 77 ka BP. Independent residue and use-wear analyses were performed in a phased procedure involving two separate analysts, which allowed the engagement between two separate lines of functional evidence. Thanks to the excellent preservation at Sibudu Cave, a wide range of animal, plant and mineral residues were observed in direct relation with diagnostic wear patterns. The combination of technological, wear and residue evidence allowed us to confirm that the serration was manufactured with bone compressors and that the serrated points were mounted with a composite adhesive as the tips of projectiles used in hunting activities. The suite of technological and functional data pushes back the evidence for the use of pressure flaking during the MSA and highlights the diversity of the technical innovations adopted by southern African MSA populations. We suggest the serrated points from the stratigraphic units Adam to Darya of Sibudu illustrate one important technological adaptation of the southern African MSA and provide another example of the variability of MSA bifacial technologies. PMID:28445544

  15. Pressure flaking to serrate bifacial points for the hunt during the MIS5 at Sibudu Cave (South Africa).

    PubMed

    Rots, Veerle; Lentfer, Carol; Schmid, Viola C; Porraz, Guillaume; Conard, Nicholas J

    2017-01-01

    Projectile technology is considered to appear early in the southern African Middle Stone Age (MSA) and the rich and high resolution MSA sequence of Sibudu Cave in KwaZulu-Natal has provided many new insights about the use and hafting of various projectile forms. We present the results of a functional and technological analysis on a series of unpublished serrated bifacial points recently recovered from the basal deposits of Sibudu Cave. These serrated tools, which only find equivalents in the neighbouring site of Umhlatuzana, precede the Still Bay techno-complex and are older than 77 ka BP. Independent residue and use-wear analyses were performed in a phased procedure involving two separate analysts, which allowed the engagement between two separate lines of functional evidence. Thanks to the excellent preservation at Sibudu Cave, a wide range of animal, plant and mineral residues were observed in direct relation with diagnostic wear patterns. The combination of technological, wear and residue evidence allowed us to confirm that the serration was manufactured with bone compressors and that the serrated points were mounted with a composite adhesive as the tips of projectiles used in hunting activities. The suite of technological and functional data pushes back the evidence for the use of pressure flaking during the MSA and highlights the diversity of the technical innovations adopted by southern African MSA populations. We suggest the serrated points from the stratigraphic units Adam to Darya of Sibudu illustrate one important technological adaptation of the southern African MSA and provide another example of the variability of MSA bifacial technologies.

  16. SEPARATIONS RESEARCH AT THE UNITED STATES ENVIRONMENTAL PROTECTION AGENCY - TOWARDS RECOVERY OF VOCS AND METALS USING MEMBRANES AND ADSORPTION PROCESSES

    EPA Science Inventory

    The USEPA's National Risk Management Research Laboratory is investigating new separations materials and processes for removal and recovery of volatile organic compounds (VOCs) and toxic metals from wastestreams and industrial process streams. Research applying membrane-based perv...

  17. 20 CFR 654.411 - Toilets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... toilet seats. (d) Except in individual family units, separate toilet accommodations for men and women shall be provided. If toilet facilities for men and women are in the same building, they shall be separated by a solid wall from floor to roof or ceiling. Toilets shall be distinctly marked “men” and “women...

  18. 20 CFR 654.411 - Toilets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... toilet seats. (d) Except in individual family units, separate toilet accommodations for men and women shall be provided. If toilet facilities for men and women are in the same building, they shall be separated by a solid wall from floor to roof or ceiling. Toilets shall be distinctly marked “men” and “women...

  19. 20 CFR 654.412 - Bathing, laundry, and handwashing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold... floor drains. Except in individual family units, separate shower facilities shall be provided each sex. When common use shower facilities for both sexes are in the same building they shall be separated by a...

  20. 20 CFR 654.412 - Bathing, laundry, and handwashing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold... floor drains. Except in individual family units, separate shower facilities shall be provided each sex. When common use shower facilities for both sexes are in the same building they shall be separated by a...

  1. 20 CFR 654.412 - Bathing, laundry, and handwashing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold... floor drains. Except in individual family units, separate shower facilities shall be provided each sex. When common use shower facilities for both sexes are in the same building they shall be separated by a...

  2. 20 CFR 654.412 - Bathing, laundry, and handwashing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold... floor drains. Except in individual family units, separate shower facilities shall be provided each sex. When common use shower facilities for both sexes are in the same building they shall be separated by a...

  3. 20 CFR 654.412 - Bathing, laundry, and handwashing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Bathing, laundry, and handwashing. (a) Bathing and handwashing facilities, supplied with hot and cold... floor drains. Except in individual family units, separate shower facilities shall be provided each sex. When common use shower facilities for both sexes are in the same building they shall be separated by a...

  4. 47 CFR 76.612 - Cable television frequency separation standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... frequency separation standards. All cable television systems which operate in the frequency bands 108-137... kHz bandwidth in any 160 microsecond period must operate at frequencies offset from certain frequencies which may be used by aeronautical radio services operated by Commission licensees or by the United...

  5. Metrics for comparing plasma mass filters

    NASA Astrophysics Data System (ADS)

    Fetterman, Abraham J.; Fisch, Nathaniel J.

    2011-10-01

    High-throughput mass separation of nuclear waste may be useful for optimal storage, disposal, or environmental remediation. The most dangerous part of nuclear waste is the fission product, which produces most of the heat and medium-term radiation. Plasmas are well-suited to separating nuclear waste because they can separate many different species in a single step. A number of plasma devices have been designed for such mass separation, but there has been no standardized comparison between these devices. We define a standard metric, the separative power per unit volume, and derive it for three different plasma mass filters: the plasma centrifuge, Ohkawa filter, and the magnetic centrifugal mass filter.

  6. Circulation Plasma Centrifuge with Product Flow

    NASA Astrophysics Data System (ADS)

    Borisevich, V. D.; Potanin, E. P.

    2018-05-01

    We have analyzed the isotope separation in a high-frequency plasma circulating centrifuge operating with a product flow. The rotation of a weakly ionized plasma is ensured by a rotating magnetic field, while the countercurrent flow (circulation) is produced by a traveling magnetic field. We have calculated the dependences of the enrichment factor and the separative power of the centrifuge on a product flow. The optimal characteristics of the separation unit have been determined.

  7. Engine Tune-up Service. Unit 2: Charging System. Posttests. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Richardson, Roger L.; Bacon, E. Miles

    This book of posttests is designed to accompany the Engine Tune-Up Service Student Guide for Unit 2, Charging System, available separately as CE 031 208. Focus of the posttest is on the testing of the charging system. One multiple choice posttest is provided, that covers the three performance objectives contained in the unit. (No answer key is…

  8. Engine Tune-Up Service. Unit 5: Fuel and Carburetion Systems. Student Guide. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Goodson, Ludy

    This student guide is for Unit 5, Fuel and Carburetion Systems, in the Engine Tune-Up Service portion of the Automotive Mechanics Curriculum. It deals with inspecting and servicing the fuel and carburetion systems. A companion review exercise book and posttests are available separately as CE 031 218-219. An introduction tells how this unit fits…

  9. Engine Tune-up Service. Unit 6: Emission Control Systems. Student Guide. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Bacon, E. Miles

    This student guide is for Unit 6, Emission Control Systems, in the Engine Tune-Up Service portion of the Automotive Mechanics Curriculum. It deals with inspecting, testing, and servicing an emission control system. A companion review exercise book and posttests are available separately as CE 031 221-222. An introduction tells how this unit fits…

  10. Engine Tune-Up Service. Unit 4: Secondary Circuit. Student Guide. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Bacon, E. Miles

    This student guide is for Unit 4, Secondary Circuit, in the Engine Tune-Up Service portion of the Automotive Mechanics Curriculum. It deals with how to test and service the secondary ignition circuit. A companion review exercise book and posttests are available separately as CE 031 215-216. An introduction tells how this unit fits into the total…

  11. Talbot effect of the defective grating in deep Fresnel region

    NASA Astrophysics Data System (ADS)

    Teng, Shuyun; Wang, Junhong; Zhang, Wei; Cui, Yuwei

    2015-02-01

    Talbot effect of the grating with different defect is studied theoretically and experimentally in this paper. The defects of grating include the loss of the diffraction unit, the dislocation of the diffraction unit and the modulation of the unit separation. The exact diffraction distributions of three kinds of defective gratings are obtained according to the finite-difference time-domain (FDTD) method. The calculation results show the image of the missing or dislocating unit appears at the Talbot distance (as mentioned in K. Patorski Prog. Opt., 27, 1989, pp.1-108). This is the so-called self-repair ability of grating imaging. In addition, some more phenomena are discovered. The loss or the dislocation of diffraction unit causes the diffraction distortion within a certain radial angle. The regular modulation of unit separation changes the original diffraction, but the new periodicity of the diffraction distribution rebuilds. The self-imaging of grating with smaller random modulation still keeps the partial self-repair ability, and yet this characteristic depends on the modulation degree of defective grating. These diffraction phenomena of the defective gratings are explained by use of the diffraction theory of grating. The practical experiment is also performed and the experimental results confirm the theoretic predictions.

  12. Oregon ground-water quality and its relation to hydrogeological factors; a statistical approach

    USGS Publications Warehouse

    Miller, T.L.; Gonthier, J.B.

    1984-01-01

    An appraisal of Oregon ground-water quality was made using existing data accessible through the U.S. Geological Survey computer system. The data available for about 1,000 sites were separated by aquifer units and hydrologic units. Selected statistical moments were described for 19 constituents including major ions. About 96 percent of all sites in the data base were sampled only once. The sample data were classified by aquifer unit and hydrologic unit and analysis of variance was run to determine if significant differences exist between the units within each of these two classifications for the same 19 constituents on which statistical moments were determined. Results of the analysis of variance indicated both classification variables performed about the same, but aquifer unit did provide more separation for some constituents. Samples from the Rogue River basin were classified by location within the flow system and type of flow system. The samples were then analyzed using analysis of variance on 14 constituents to determine if there were significant differences between subsets classified by flow path. Results of this analysis were not definitive, but classification as to the type of flow system did indicate potential for segregating water-quality data into distinct subsets. (USGS)

  13. Pollution control of industrial wastewater from soap and oil industries: a case study.

    PubMed

    Abdel-Gawad, S; Abdel-Shafy, M

    2002-01-01

    Industrial wastewater from soap and oil industries represents a heavy pollution source on their receiving water body. This paper studies a case of pollution control at Tanta Soap and Oil Company, Banha Factory, Egypt. The factory production includes soap, edible oil, and animal fodder. About 4,347 m3/day of industrial wastewater effluent was discharged via gravity sewers to the public sewerage system. Most of the effluent was cooling water because the cooling process in the factory was open circle. In spite of the huge quantity of cooling water being disposed of, disposal of wastewater was violating pertinent legislation. Three procedures were used for controlling the pollution at the Banha Factory. Firstly, all open circuit cooling systems were converted to closed circuit thus reducing the quantity of the discharged wastewater down to 767 m3/day. Secondly, the heavily polluted oil and grease (O&G) wastewater from the refinery unit is treated via two gravity oil separator (GOS) units, dissolved air floatation (DAF), and biological units in order to reduce the high levels of O&G, BOD, COD, and SS to the allowable limits. Thirdly, the heavily polluted waste effluent from the 'red water' saponification unit is treated separately by acidification to convert the emulsified fatty acid to free form in order to be separated through an oil separation unit. The effluent is then passed to liming stage to neutralize excess acidity and precipitate some of the dissolved matters. The mixture is finally clarified and the pH is adjusted to the allowable limits. The effluent wastewater from the three processes is collected and mixed in a final equalization tank for discharging effluent to the public sewerage system. The characteristics of the effluent water are very good with respect to the allowable Egyptian limits for discharging effluent to the public sewerage system.

  14. Application of CFD in Bioprocessing: Separation of mammalian cells using disc stack centrifuge during production of biotherapeutics.

    PubMed

    Shekhawat, Lalita Kanwar; Sarkar, Jayati; Gupta, Rachit; Hadpe, Sandeep; Rathore, Anurag S

    2018-02-10

    Centrifugation continues to be one of the most commonly used unit operations for achieving efficient harvest of the product from the mammalian cell culture broth during production of therapeutic monoclonal antibodies (mAbs). Since the mammalian cells are known to be shear sensitive, optimal performance of the centrifuge requires a balance between productivity and shear. In this study, Computational Fluid Dynamics (CFD) has been successfully used as a tool to facilitate efficient optimization. Multiphase Eulerian-Eulerian model coupled with Gidaspow drag model along with Eulerian-Eulerian k-ε mixture turbulence model have been used to quantify the complex hydrodynamics of the centrifuge and thus evaluate the turbulent stresses generated by the centrifugal forces. An empirical model has been developed by statistical analysis of experimentally observed cell lysis data as a function of turbulent stresses. An operating window that offers the optimal balance between high productivity, high separation efficiency, and low cell damage has been identified by use of CFD modeling. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. A new financial budgetary system for community health services institutions in China.

    PubMed

    You, Chuanmei; Yao, Lan; Fu, Jiakang; Wang, Fang; Wang, Hongqing; Dai, Tao

    2011-01-01

    The separation of revenue and expenditure budgets (SREB) is a new financial budgetary system that is being implemented in community health services (CHS) institutions in some areas in China. Through literature review, it was found that, derived from the traditional separation of revenue and expenditure budgets (TSREB) implemented in administrative public services units, SREB and TSREB have something in common and yet many more differences. On the basis of some quantitative and qualitative data that were collected by field survey, it was also found that implementation of SREB in CHS institutions brings positive outcomes in terms of the quantity, quality and efficiency of services; residents' satisfaction; and the behavior of CHS institutions. The conclusion can be suggested that SREB, as a system having impact upon the incentives facing CHS institutions and the nature of governmental responsibility for developing CHS in China, will promote CHS institutions to fulfill basic service functions if implemented well. Therefore, it is a system that is worth further development and evaluation. Copyright © 2011 John Wiley & Sons, Ltd.

  16. Epoxy-based hydrogels investigated by high-frequency dielectric relaxation spectroscopy.

    PubMed

    Krakovský, Ivan; Shikata, Toshiyuki; Hasegawa, Ryuta

    2013-11-14

    Using high-frequency dielectric relaxation spectroscopy, nanophase-separated structures of epoxy-based hydrogels were investigated as a function of water content at 25 °C. The dielectric spectra resulting from the hydrogels were reasonably decomposed into two Debye-type and two Cole-Cole-type relaxation modes. The fastest Debye-type mode, found at 8.3 ps, was attributed to the rotational relaxation process of free water molecules in the bulk state. The other Debye-type mode, at ca. 20-34 ps, originates from the exchange process of water molecules that are hydrogen-bonded to the hydrophilic epoxy network portions for free bulk ones. The first Cole-Cole-type mode observed, at ca. 20-370 ps, was assigned to the complicated dynamics for electric dipole moments of the hydrophilic groups in the epoxy networks (mainly monomeric oxyethylene units). The slowest major Cole-Cole-type mode, at 5-29 ns, was attributed to the Maxwell-Wagner-Sillars polarization process and confirmed the presence of the nanophase-separated structures as revealed by the previous small-angle neutron scattering experiments.

  17. Towards an entropy-based detached-eddy simulation

    NASA Astrophysics Data System (ADS)

    Zhao, Rui; Yan, Chao; Li, XinLiang; Kong, WeiXuan

    2013-10-01

    A concept of entropy increment ratio ( s¯) is introduced for compressible turbulence simulation through a series of direct numerical simulations (DNS). s¯ represents the dissipation rate per unit mechanical energy with the benefit of independence of freestream Mach numbers. Based on this feature, we construct the shielding function f s to describe the boundary layer region and propose an entropy-based detached-eddy simulation method (SDES). This approach follows the spirit of delayed detached-eddy simulation (DDES) proposed by Spalart et al. in 2005, but it exhibits much better behavior after their performances are compared in the following flows, namely, pure attached flow with thick boundary layer (a supersonic flat-plate flow with high Reynolds number), fully separated flow (the supersonic base flow), and separated-reattached flow (the supersonic cavity-ramp flow). The Reynolds-averaged Navier-Stokes (RANS) resolved region is reliably preserved and the modeled stress depletion (MSD) phenomenon which is inherent in DES and DDES is partly alleviated. Moreover, this new hybrid strategy is simple and general, making it applicable to other models related to the boundary layer predictions.

  18. Influence of White and Gray Matter Connections on Endogenous Human Cortical Oscillations

    PubMed Central

    Hawasli, Ammar H.; Kim, DoHyun; Ledbetter, Noah M.; Dahiya, Sonika; Barbour, Dennis L.; Leuthardt, Eric C.

    2016-01-01

    Brain oscillations reflect changes in electrical potentials summated across neuronal populations. Low- and high-frequency rhythms have different modulation patterns. Slower rhythms are spatially broad, while faster rhythms are more local. From this observation, we hypothesized that low- and high-frequency oscillations reflect white- and gray-matter communications, respectively, and synchronization between low-frequency phase with high-frequency amplitude represents a mechanism enabling distributed brain-networks to coordinate local processing. Testing this common understanding, we selectively disrupted white or gray matter connections to human cortex while recording surface field potentials. Counter to our original hypotheses, we found that cortex consists of independent oscillatory-units (IOUs) that maintain their own complex endogenous rhythm structure. IOUs are differentially modulated by white and gray matter connections. White-matter connections maintain topographical anatomic heterogeneity (i.e., separable processing in cortical space) and gray-matter connections segregate cortical synchronization patterns (i.e., separable temporal processing through phase-power coupling). Modulation of distinct oscillatory modules enables the functional diversity necessary for complex processing in the human brain. PMID:27445767

  19. Neural Correlates and Mechanisms of Spatial Release From Masking: Single-Unit and Population Responses in the Inferior Colliculus

    PubMed Central

    Lane, Courtney C.; Delgutte, Bertrand

    2007-01-01

    Spatial release from masking (SRM), a factor in listening in noisy environments, is the improvement in auditory signal detection obtained when a signal is separated in space from a masker. To study the neural mechanisms of SRM, we recorded from single units in the inferior colliculus (IC) of barbiturate-anesthetized cats, focusing on low-frequency neurons sensitive to interaural time differences. The stimulus was a broadband chirp train with a 40-Hz repetition rate in continuous broadband noise, and the unit responses were measured for several signal and masker (virtual) locations. Masked thresholds (the lowest signal-to-noise ratio, SNR, for which the signal could be detected for 75% of the stimulus presentations) changed systematically with signal and masker location. Single-unit thresholds did not necessarily improve with signal and masker separation; instead, they tended to reflect the units’ azimuth preference. Both how the signal was detected (through a rate increase or decrease) and how the noise masked the signal response (suppressive or excitatory masking) changed with signal and masker azimuth, consistent with a cross-correlator model of binaural processing. However, additional processing, perhaps related to the signal’s amplitude modulation rate, appeared to influence the units’ responses. The population masked thresholds (the most sensitive unit’s threshold at each signal and masker location) did improve with signal and masker separation as a result of the variety of azimuth preferences in our unit sample. The population thresholds were similar to human behavioral thresholds in both SNR value and shape, indicating that these units may provide a neural substrate for low-frequency SRM. PMID:15857966

  20. Gossypol-Capped Mitoxantrone-Loaded Mesoporous SiO2 NPs for the Cooperative Controlled Release of Two Anti-Cancer Drugs.

    PubMed

    Heleg-Shabtai, Vered; Aizen, Ruth; Sharon, Etery; Sohn, Yang Sung; Trifonov, Alexander; Enkin, Natalie; Freage, Lina; Nechushtai, Rachel; Willner, Itamar

    2016-06-15

    Mesoporous SiO2 nanoparticles, MP-SiO2 NPs, are functionalized with the boronic acid ligand units. The pores of the MP-SiO2 NPs are loaded with the anticancer drug mitoxantrone, and the pores are capped with the anticancer drug gossypol. The resulting two-drug-functionalized MP-SiO2 NPs provide a potential stimuli-responsive anticancer drug carrier for cooperative chemotherapeutic treatment. In vitro experiments reveal that the MP-SiO2 NPs are unlocked under environmental conditions present in cancer cells, e.g., acidic pH and lactic acid overexpressed in cancer cells. The effective unlocking of the capping units under these conditions is attributed to the acidic hydrolysis of the boronate ester capping units and to the cooperative separation of the boronate ester bridges by the lactate ligand. The gossypol-capped mitoxantrone-loaded MP-SiO2 NPs reveals preferential cytotoxicity toward cancer cells and cooperative chemotherapeutic activities toward the cancer cells. The MCF-10A epithelial breast cells and the malignant MDA-MB-231 breast cancer cells treated with the gossypol-capped mitoxantrone-loaded MP-SiO2 NPs revealed after a time-interval of 5 days a cell death of ca. 8% and 60%, respectively. Also, the gossypol-capped mitoxantrone-loaded MP-SiO2 NPs revealed superior cancer-cell death (ca. 60%) as compared to control carriers consisting of β-cyclodextrin-capped mitoxantrone-loaded (ca. 40%) under similar loading of the mitoxantrone drug. The drugs-loaded MP-SiO2 NPs reveal impressive long-term stabilities.

  1. A trilayer separator with dual function for high performance lithium-sulfur batteries

    NASA Astrophysics Data System (ADS)

    Song, Rensheng; Fang, Ruopian; Wen, Lei; Shi, Ying; Wang, Shaogang; Li, Feng

    2016-01-01

    In this article, we propose a trilayer graphene/polypropylene/Al2O3 (GPA) separator with dual function for high performance lithium-sulfur (Li-S) batteries. Graphene is coated on one side of polypropylene (PP) separator, which functions as a conductive layer and an electrolyte reservoir that allows for rapid electron and ion transport. Then Al2O3 particles are coated on the other side to further enhance thermal stability and safety of the graphene coated polypropylene (GCP) separator, which are touched with lithium metal anode in the Li-S battery. The GPA separator shows good thermal stability after heating at 157 °C for 10 min while both GCP and PP separators showing an obvious shrinkage about 10%. The initial discharge specific capacity of Li-S coin cell with a GPA separator could reach 1067.7 mAh g-1 at 0.2C. After 100 discharge/charge cycles, it can still deliver a reversible capacity of as high as 804.4 mAh g-1 with 75% capacity retention. The pouch cells further confirm that the trilayer design has great promise towards practical applications.

  2. Deployable Crew Quarters

    NASA Technical Reports Server (NTRS)

    Izenson, Michael G.; Chen, Weibo

    2008-01-01

    The deployable crew quarters (DCQ) have been designed for the International Space Station (ISS). Each DCQ would be a relatively inexpensive, deployable boxlike structure that is designed to fit in a rack bay. It is to be occupied by one crewmember to provide privacy and sleeping functions for the crew. A DCQ comprises mostly hard panels, made of a lightweight honeycomb or matrix/fiber material, attached to each other by cloth hinges. Both faces of each panel are covered with a layer of Nomex cloth and noise-suppression material to provide noise isolation from ISS. On Earth, the unit is folded flat and attached to a rigid pallet for transport to the ISS. On the ISS, crewmembers unfold the unit and install it in place, attaching it to ISS structural members by use of soft cords (which also help to isolate noise and vibration). A few hard pieces of equipment (principally, a ventilator and a smoke detector) are shipped separately and installed in the DCQ unit by use of a system of holes, slots, and quarter-turn fasteners. Full-scale tests showed that the time required to install a DCQ unit amounts to tens of minutes. The basic DCQ design could be adapted to terrestrial applications to satisfy requirements for rapid deployable emergency shelters that would be lightweight, portable, and quickly erected. The Temporary Early Sleep Station (TeSS) currently on-orbit is a spin-off of the DCQ.

  3. Water-use computer programs for Florida

    USGS Publications Warehouse

    Geiger, L.H.

    1984-01-01

    Using U.S. Geological Survey computer programs L149-L153, this report shows how to process water-use data for the functional water-use categories: public supply, rural supply, industrial self-supplied, irrigation, and thermo-electric power generation. The programs are used to selectively retrieve entries and list them in a format suitable for publication. Instructions are given for coding cards to produce tables of water-use data for each of the functional use categories. These cards contain entries that identify a particular water-use data-collection site in Florida. Entries on the cards include location information such as county code, water management district code, hydrologic unit code, and, where applicable, a site name and number. Annual and monthly pumpage is included. These entries are shown with several different headings; for example, surface water or ground water, freshwater or saline pumpages, or consumptive use. All the programs use a similar approach; however, the actual programs differ with each functional water-use category and are discussed separately. Data prepared for these programs can also be processed by the National Water-Use Data System. (USGS)

  4. Generalized Wall Function for Complex Turbulent Flows

    NASA Technical Reports Server (NTRS)

    Shih, Tsan-Hsing; Povinelli, Louis A.; Liu, Nan-Suey; Chen, Kuo-Huey

    2000-01-01

    A generalized wall function was proposed by Shih et al., (1999). It accounts the effect of pressure gradients on the flow near the wall. Theory shows that the effect of pressure gradients on the flow in the inertial sublayer is very significant and the standard wall function should be replaced by a generalized wall function. Since the theory is also valid for boundary layer flows toward separation, the generalized wall function may be applied to complex turbulent flows with acceleration, deceleration, separation and recirculation. This paper is to verify the generalized wall function with numerical simulations for boundary layer flows with various adverse and favorable pressure gradients, including flows about to separate. Furthermore, a general procedure of implementation of the generalized wall function for National Combustion Code (NCC) is described, it can be applied to both structured and unstructured CFD codes.

  5. Prima Platform: A Scheme for Managing Equipment-Dependent Onboard Functions and Impacts on the Avionics Software Production Process

    NASA Astrophysics Data System (ADS)

    Candia, Sante; Lisio, Giovanni; Campolo, Giovanni; Pascucci, Dario

    2010-08-01

    The Avionics Software (ASW), in charge of controlling the Low Earth Orbit (LEO) Spacecraft PRIMA Platform (Piattaforma Ri-configurabile Italiana Multi-Applicativa), is evolving towards a highly modular and re-usable architecture based on an architectural framework allowing the effective integration of the software building blocks (SWBBs) providing the on-board control functions. During the recent years, the PRIMA ASW design and production processes have been improved to reach the following objectives: (a) at PUS Services level, separation of the mission-independent software mechanisms from the mission-dependent configuration information; (b) at Application level, identification of mission-independent recurrent functions for promoting abstraction and obtaining a more efficient and safe ASW production, with positive implications also on the software validation activities. This paper is dedicated to the characterisation activity which has been performed at Application level for a software component abstracting a set of functions for the generic On-Board Assembly (OBA), a set of hardware units used to deliver an on-board service. Moreover, the ASW production process is specified to show how it results after the introduction of the new design features.

  6. Single-hole spectral function and spin-charge separation in the t-J model

    NASA Astrophysics Data System (ADS)

    Mishchenko, A. S.; Prokof'ev, N. V.; Svistunov, B. V.

    2001-07-01

    Worm algorithm Monte Carlo simulations of the hole Green function with subsequent spectral analysis were performed for 0.1<=J/t<=0.4 on lattices with up to L×L=32×32 sites at a temperature as low as T=J/40, and present, apparently, the hole spectral function in the thermodynamic limit. Spectral analysis reveals a δ-function-sharp quasiparticle peak at the lower edge of the spectrum that is incompatible with the power-law singularity and thus rules out the possibility of spin-charge separation in this parameter range. Spectral continuum features two peaks separated by a gap ~4÷5 t.

  7. 38 CFR 41.310 - Financial statements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... year audited. The financial statements shall be for the same organizational unit and fiscal year that... also include departments, agencies, and other organizational units that have separate audits in.... For example, the National Institutes of Health is a major subdivision in the Department of Health and...

  8. 38 CFR 41.310 - Financial statements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... year audited. The financial statements shall be for the same organizational unit and fiscal year that... also include departments, agencies, and other organizational units that have separate audits in.... For example, the National Institutes of Health is a major subdivision in the Department of Health and...

  9. EPA RREL'S MOBILE VOLUME REDUCTION UNIT -- APPLICATIONS ANALYSIS REPORT

    EPA Science Inventory

    The volume reduction unit (VRU) is a pilot-scale, mobile soil washing system designed to remove organic contaminants from the soil through particle size separation and solubilization. The VRU removes contaminants by suspending them in a wash solution and by reducing the volume of...

  10. Business Education Resources.

    ERIC Educational Resources Information Center

    Alaska State Dept. of Education, Juneau. Div. of Adult and Vocational Education.

    This guide contains instructional materials to aid business education teachers in teaching business skills in Alaska secondary schools. The materials include five units covering the following topics: human relations as a separate unit and as integrated into other daily activities such as planning and organizing work activities and grooming,…

  11. Preparation of a novel dual-function strong cation exchange/hydrophobic interaction chromatography stationary phase for protein separation.

    PubMed

    Zhao, Kailou; Yang, Li; Wang, Xuejiao; Bai, Quan; Yang, Fan; Wang, Fei

    2012-08-30

    We have explored a novel dual-function stationary phase which combines both strong cation exchange (SCX) and hydrophobic interaction chromatography (HIC) characteristics. The novel dual-function stationary phase is based on porous and spherical silica gel functionalized with ligand containing sulfonic and benzyl groups capable of electrostatic and hydrophobic interaction functionalities, which displays HIC character in a high salt concentration, and IEC character in a low salt concentration in mobile phase employed. As a result, it can be employed to separate proteins with SCX and HIC modes, respectively. The resolution and selectivity of the dual-function stationary phase were evaluated under both HIC and SCX modes with standard proteins and can be comparable to that of conventional IEC and HIC columns. More than 96% of mass and bioactivity recoveries of proteins can be achieved in both HIC and SCX modes, respectively. The results indicated that the novel dual-function column could replace two individual SCX and HIC columns for protein separation. Mixed retention mechanism of proteins on this dual-function column based on stoichiometric displacement theory (SDT) in LC was investigated to find the optimal balance of the magnitude of electrostatic and hydrophobic interactions between protein and the ligand on the silica surface in order to obtain high resolution and selectivity for protein separation. In addition, the effects of the hydrophobicity of the ligand of the dual-function packings and pH of the mobile phase used on protein separation were also investigated in detail. The results show that the ligand with suitable hydrophobicity to match the electrostatic interaction is very important to prepare the dual-function stationary phase, and a better resolution and selectivity can be obtained at pH 6.5 in SCX mode. Therefore, the dual-function column can replace two individual SCX and HIC columns for protein separation and be used to set up two-dimensional liquid chromatography with a single column (2DLC-1C), which can also be employed to separate three kinds of active proteins completely, such as lysozyme, ovotransferrin and ovalbumin from egg white. The result is very important not only to the development of new 2DLC technology with a single column for proteomics, but also to recombinant protein drug production for saving column expense and simplifying the process in biotechnology. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. The mediating role of metacognition in the relationship between executive function and self-regulated learning.

    PubMed

    Follmer, D Jake; Sperling, Rayne A

    2016-12-01

    Researchers have demonstrated significant relations among executive function, metacognition, and self-regulated learning. However, prior research emphasized the use of indirect measures of executive function and did not evaluate how specific executive functions are related to participants' self-regulated learning. The primary goals of the current study were to examine and test the relations among executive function, metacognition, and self-regulated learning as well as to examine how self-regulated learning is informed by executive function. The sample comprised 117 undergraduate students attending a large, Mid-Atlantic research university in the United States. Participants were individually administered direct and indirect measures of executive function, metacognition, and self-regulated learning. A mediation model specifying the relations among the regulatory constructs was proposed. In multiple linear regression analyses, executive function predicted metacognition and self-regulated learning. Direct measures of inhibition and shifting accounted for a significant amount of the variance in metacognition and self-regulated learning beyond an indirect measure of executive functioning. Separate mediation analyses indicated that metacognition mediated the relationship between executive functioning and self-regulated learning as well as between specific executive functions and self-regulated learning. The findings of this study are supported by previous research documenting the relations between executive function and self-regulated learning, and extend prior research by examining the manner in which executive function and self-regulated learning are linked. The findings provide initial support for executive functions as key processes, mediated by metacognition, that predict self-regulated learning. Implications for the contribution of executive functions to self-regulated learning are discussed. © 2016 The British Psychological Society.

  13. 40 CFR 33.402 - Are there special rules for loans under EPA financial assistance agreements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... agreement to capitalize revolving loan funds must either apply its own fair share objectives negotiated with... UNITED STATES ENVIRONMENTAL PROTECTION AGENCY PROGRAMS Fair Share Objectives § 33.402 Are there special... negotiate separate fair share objectives with entities receiving identified loans, as long as such separate...

  14. Demographic Trends in the United States: A Review of Research in the 2000s

    ERIC Educational Resources Information Center

    Cherlin, Andrew J.

    2010-01-01

    Demographic trends in the 2000s showed the continuing separation of family and household because of factors such as childbearing among single parents, the dissolution of cohabiting unions, divorce, repartnering, and remarriage. The transnational families of many immigrants also displayed this separation, as families extended across borders. In…

  15. Nutrient Database improvement project: Separable components and proximate composition of retail cuts from the beef chuck

    USDA-ARS?s Scientific Manuscript database

    This study was designed to provide updated information on the separable components, cooking yields, and nutrient values of retail cuts from the beef chuck. Ultimately, these data will be used in the United States Department of Agriculture (USDA) Nutrient Data Laboratory’s (NDL) National Nutrient Da...

  16. Engine Tune-Up Service. Unit 3: Primary Circuit. Student Guide. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Bacon, E. Miles

    This student guide is for Unit 3, Primary Circuit, in the Engine Tune-Up Service portion of the Automotive Mechanics Curriculum. It deals with how to test the primary ignition circuit. A companion review exercise book and posttests are available separately as CE 031 212-213. An introduction tells how this unit fits into the total tune-up service,…

  17. Engine Tune-up Service. Unit 2: Charging System. Student Guide. Automotive Mechanics Curriculum.

    ERIC Educational Resources Information Center

    Richardson, Roger L.; Bacon, E. Miles

    This student guide is for Unit 2, Charging System, in the Engine Tune-Up Service portion of the Automotive Mechanics Curriculum. It deals with how to test the charging system. A companion review exercise book and posttests are available separately as CE 031 209-210. An introduction tells how this unit fits into the total tune-up service, defines…

  18. The environment power system analysis tool development program

    NASA Technical Reports Server (NTRS)

    Jongeward, Gary A.; Kuharski, Robert A.; Kennedy, Eric M.; Stevens, N. John; Putnam, Rand M.; Roche, James C.; Wilcox, Katherine G.

    1990-01-01

    The Environment Power System Analysis Tool (EPSAT) is being developed to provide space power system design engineers with an analysis tool for determining system performance of power systems in both naturally occurring and self-induced environments. The program is producing an easy to use computer aided engineering (CAE) tool general enough to provide a vehicle for technology transfer from space scientists and engineers to power system design engineers. The results of the project after two years of a three year development program are given. The EPSAT approach separates the CAE tool into three distinct functional units: a modern user interface to present information, a data dictionary interpreter to coordinate analysis; and a data base for storing system designs and results of analysis.

  19. Endoscopic sensing of alveolar pH

    PubMed Central

    Choudhury, D.; Tanner, M. G.; McAughtrie, S.; Yu, F.; Mills, B.; Choudhary, T. R.; Seth, S.; Craven, T. H.; Stone, J. M.; Mati, I. K.; Campbell, C. J.; Bradley, M.; Williams, C. K. I.; Dhaliwal, K.; Birks, T. A.; Thomson, R. R.

    2016-01-01

    Previously unobtainable measurements of alveolar pH were obtained using an endoscope-deployable optrode. The pH sensing was achieved using functionalized gold nanoshell sensors and surface enhanced Raman spectroscopy (SERS). The optrode consisted of an asymmetric dual-core optical fiber designed for spatially separating the optical pump delivery and signal collection, in order to circumvent the unwanted Raman signal generated within the fiber. Using this approach, we demonstrate a ~100-fold increase in SERS signal-to-fiber background ratio, and demonstrate multiple site pH sensing with a measurement accuracy of ± 0.07 pH units in the respiratory acini of an ex vivo ovine lung model. We also demonstrate that alveolar pH changes in response to ventilation. PMID:28101415

  20. [Research of joint-robotics-based design of biomechanics testing device on human spine].

    PubMed

    Deng, Guoyong; Tian, Lianfang; Mao, Zongyuan

    2009-12-01

    This paper introduces the hardware and software of a biomechanical robot-based testing device. The bottom control orders, posture and torque data transmission, and the control algorithms are integrated in a unified visual control platform by Visual C+ +, with easy control and management. By using hybrid force-displacement control method to load the human spine, we can test the organizational structure and the force state of the FSU (Functional spinal unit) well, which overcomes the shortcomings due to the separation of the force and displacement measurement, thus greatly improves the measurement accuracy. Also it is esay to identify the spinal degeneration and the load-bearing impact on the organizational structure of the FSU after various types of surgery.

  1. Metasurface polarization splitter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slovick, Brian A.; Zhou, You; Yu, Zhi Gang

    Polarization beam splitters, devices that separate the two orthogonal polarizations of light into different propagation directions, are among the most ubiquitous optical elements. However, traditionally polarization splitters rely on bulky optical materials, while emerging optoelectronic and photonic circuits require compact, chip-scale polarization splitters. Here, we show that a rectangular lattice of cylindrical silicon Mie resonators functions as a polarization splitter, efficiently reflecting one polarization while transmitting the other. We show that the polarization splitting arises from the anisotropic permittivity and permeability of the metasurface due to the twofold rotational symmetry of the rectangular unit cell. Lastly, the high polarization efficiency,more » low loss and low profile make these metasurface polarization splitters ideally suited for monolithic integration with optoelectronic and photonic circuits.« less

  2. Metasurface polarization splitter

    DOE PAGES

    Slovick, Brian A.; Zhou, You; Yu, Zhi Gang; ...

    2017-02-20

    Polarization beam splitters, devices that separate the two orthogonal polarizations of light into different propagation directions, are among the most ubiquitous optical elements. However, traditionally polarization splitters rely on bulky optical materials, while emerging optoelectronic and photonic circuits require compact, chip-scale polarization splitters. Here, we show that a rectangular lattice of cylindrical silicon Mie resonators functions as a polarization splitter, efficiently reflecting one polarization while transmitting the other. We show that the polarization splitting arises from the anisotropic permittivity and permeability of the metasurface due to the twofold rotational symmetry of the rectangular unit cell. Lastly, the high polarization efficiency,more » low loss and low profile make these metasurface polarization splitters ideally suited for monolithic integration with optoelectronic and photonic circuits.« less

  3. Testing Orions Fairing Separation System

    NASA Technical Reports Server (NTRS)

    Martinez, Henry; Cloutier, Chris; Lemmon, Heber; Rakes, Daniel; Oldham, Joe; Schlagel, Keith

    2014-01-01

    Traditional fairing systems are designed to fully encapsulate and protect their payload from the harsh ascent environment including acoustic vibrations, aerodynamic forces and heating. The Orion fairing separation system performs this function and more by also sharing approximately half of the vehicle structural load during ascent. This load-share condition through launch and during jettison allows for a substantial increase in mass to orbit. A series of component-level development tests were completed to evaluate and characterize each component within Orion's unique fairing separation system. Two full-scale separation tests were performed to verify system-level functionality and provide verification data. This paper summarizes the fairing spring, Pyramidal Separation Mechanism and forward seal system component-level development tests, system-level separation tests, and lessons learned.

  4. Design Issues Affecting Pipings Associated with a New Moisture Separator Reheater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hyung-Keun, Kim; Jae-Kyoung, Cho

    2006-07-01

    This paper summarizes the piping design effects on a New Moisture Separator Reheater (MSR) in Shin-Kori Nuclear Power Plant Units 1 and 2 (SKN 1 and 2) being under the construction in Korea. This SKN 1 and 2 has the same arrangement of a Turbine-Generator set as one of Korea Standard Nuclear Plant Units ( OPR 1000 ) in commercial operation. The Turbine-Generator Supplier has developed a new Moisture Separator Reheater which has first and second stage heating steam supply connections respectively, at both ends of the shell side of the vessel in comparison to MSR of OPR 1000 whichmore » has first and second stage heating steam supply connections at only one end. The different locations of reheaters in MSR cause changes in the associated pipings such as 2. stage reheater heating steam, 2. stage reheater drain, shell drain, drain tank location and tank condensate drainage pipings. (authors)« less

  5. Documentation of a computer program to simulate transient leakage from confining units using the modular finite-difference, ground-water flow model

    USGS Publications Warehouse

    Leake, S.A.; Leahy, P.P.; Navoy, A.S.

    1994-01-01

    Transient leakage into or out of a compressible fine-grained confining unit results from ground- water storage changes within the unit. The computer program described in this report provides a new method of simulating transient leakage using the U.S. Geological Survey modular finite- difference ground-water flow model (MODFLOW). The new program is referred to as the Transient- Leakage Package. The Transient-Leakage Package solves integrodifferential equations that describe flow across the upper and lower boundaries of confining units. For each confining unit, vertical hydraulic conductivity, thickness, and specific storage are specified in input arrays. These properties can vary from cell to cell and the confining unit need not be present at all locations in the grid; however, the confining units must be bounded above and below by model layers in which head is calculated or specified. The package was used in an example problem to simulate drawdown around a pumping well in a system with two aquifers separated by a confining unit. For drawdown values in excess of 1 centimeter, the solution using the new package closely matched an exact analytical solution. The problem also was simulated without the new package by using a separate model layer to represent the confining unit. That simulation was refined by using two model layers to represent the confining unit. The simulation using the Transient-Leakage Package was faster and more accurate than either of the simulations using model layers to represent the confining unit.

  6. Dancing together and separate again: gymnosperms exhibit frequent changes of fundamental 5S and 35S rRNA gene (rDNA) organisation

    PubMed Central

    Garcia, S; Kovařík, A

    2013-01-01

    In higher eukaryotes, the 5S rRNA genes occur in tandem units and are arranged either separately (S-type arrangement) or linked to other repeated genes, in most cases to rDNA locus encoding 18S–5.8S–26S genes (L-type arrangement). Here we used Southern blot hybridisation, PCR and sequencing approaches to analyse genomic organisation of rRNA genes in all large gymnosperm groups, including Coniferales, Ginkgoales, Gnetales and Cycadales. The data are provided for 27 species (21 genera). The 5S units linked to the 35S rDNA units occur in some but not all Gnetales, Coniferales and in Ginkgo (∼30% of the species analysed), while the remaining exhibit separate organisation. The linked 5S rRNA genes may occur as single-copy insertions or as short tandems embedded in the 26S–18S rDNA intergenic spacer (IGS). The 5S transcript may be encoded by the same (Ginkgo, Ephedra) or opposite (Podocarpus) DNA strand as the 18S–5.8S–26S genes. In addition, pseudogenised 5S copies were also found in some IGS types. Both L- and S-type units have been largely homogenised across the genomes. Phylogenetic relationships based on the comparison of 5S coding sequences suggest that the 5S genes independently inserted IGS at least three times in the course of gymnosperm evolution. Frequent transpositions and rearrangements of basic units indicate relatively relaxed selection pressures imposed on genomic organisation of 5S genes in plants. PMID:23512008

  7. Dancing together and separate again: gymnosperms exhibit frequent changes of fundamental 5S and 35S rRNA gene (rDNA) organisation.

    PubMed

    Garcia, S; Kovařík, A

    2013-07-01

    In higher eukaryotes, the 5S rRNA genes occur in tandem units and are arranged either separately (S-type arrangement) or linked to other repeated genes, in most cases to rDNA locus encoding 18S-5.8S-26S genes (L-type arrangement). Here we used Southern blot hybridisation, PCR and sequencing approaches to analyse genomic organisation of rRNA genes in all large gymnosperm groups, including Coniferales, Ginkgoales, Gnetales and Cycadales. The data are provided for 27 species (21 genera). The 5S units linked to the 35S rDNA units occur in some but not all Gnetales, Coniferales and in Ginkgo (∼30% of the species analysed), while the remaining exhibit separate organisation. The linked 5S rRNA genes may occur as single-copy insertions or as short tandems embedded in the 26S-18S rDNA intergenic spacer (IGS). The 5S transcript may be encoded by the same (Ginkgo, Ephedra) or opposite (Podocarpus) DNA strand as the 18S-5.8S-26S genes. In addition, pseudogenised 5S copies were also found in some IGS types. Both L- and S-type units have been largely homogenised across the genomes. Phylogenetic relationships based on the comparison of 5S coding sequences suggest that the 5S genes independently inserted IGS at least three times in the course of gymnosperm evolution. Frequent transpositions and rearrangements of basic units indicate relatively relaxed selection pressures imposed on genomic organisation of 5S genes in plants.

  8. Definition and classification of evaluation units for tertiary structure prediction in CASP12 facilitated through semi-automated metrics.

    PubMed

    Abriata, Luciano A; Kinch, Lisa N; Tamò, Giorgio E; Monastyrskyy, Bohdan; Kryshtafovych, Andriy; Dal Peraro, Matteo

    2018-03-01

    For assessment purposes, CASP targets are split into evaluation units. We herein present the official definition of CASP12 evaluation units (EUs) and their classification into difficulty categories. Each target can be evaluated as one EU (the whole target) or/and several EUs (separate structural domains or groups of structural domains). The specific scenario for a target split is determined by the domain organization of available templates, the difference in server performance on separate domains versus combination of the domains, and visual inspection. In the end, 71 targets were split into 96 EUs. Classification of the EUs into difficulty categories was done semi-automatically with the assistance of metrics provided by the Prediction Center. These metrics account for sequence and structural similarities of the EUs to potential structural templates from the Protein Data Bank, and for the baseline performance of automated server predictions. The metrics readily separate the 96 EUs into 38 EUs that should be straightforward for template-based modeling (TBM) and 39 that are expected to be hard for homology modeling and are thus left for free modeling (FM). The remaining 19 borderline evaluation units were dubbed FM/TBM, and were inspected case by case. The article also overviews structural and evolutionary features of selected targets relevant to our accompanying article presenting the assessment of FM and FM/TBM predictions, and overviews structural features of the hardest evaluation units from the FM category. We finally suggest improvements for the EU definition and classification procedures. © 2017 Wiley Periodicals, Inc.

  9. First flight test results of the Simplified Aid For EVA Rescue (SAFER) propulsion unit

    NASA Technical Reports Server (NTRS)

    Meade, Carl J.

    1995-01-01

    The Simplified Aid for EVA Rescue (SAFER) is a small, self-contained, propulsive-backpack system that provides free-flying mobility for an astronaut engaged in a space walk, also known as extravehicular activity (EVA.) SAFER contains no redundant systems and is intended for contingency use only. In essence, it is a small, simplified version of the Manned Maneuvering Unit (MMU) last flown aboard the Space Shuttle in 1985. The operational SAFER unit will only be used to return an adrift EVA astronaut to the spacecraft. Currently, if an EVA crew member inadvertently becomes separated from the Space Shuttle, the Orbiter will maneuver to within the crew member's reach envelope, allowing the astronaut to regain contact with the Orbiter. However, with the advent of operations aboard the Russian MIR Space Station and the International Space Station, the Space Shuttle will not be available to effect a timely rescue. Under these conditions, a SAFER unit would be worn by each EVA crew member. Flight test of the pre-production model of SAFER occurred in September 1994. The crew of Space Shuttle Mission STS-64 flew a 6.9 hour test flight which included performance, flying qualities, systems, and operational utility evaluations. We found that the unit offers adequate propellant and control authority to stabilize and enable the return of a tumbling/separating crew member. With certain modifications, production model of SAFER can provide self-rescue capability to a separated crew member. This paper will present the program background, explain the flight test results and provide some insight into the complex operations of flight test in space.

  10. Abnormal pulmonary function and respiratory muscle strength findings in Chinese patients with Parkinson's disease and multiple system atrophy--comparison with normal elderly.

    PubMed

    Wang, Yao; Shao, Wei-bo; Gao, Li; Lu, Jie; Gu, Hao; Sun, Li-hua; Tan, Yan; Zhang, Ying-dong

    2014-01-01

    There have been limited comparative data regarding the investigations on pulmonary and respiratory muscle function in the patients with different parkinsonism disorders such as Parkinson's disease (PD) and multiple system atrophy (MSA) versus normal elderly. The present study is aiming to characterize the performance of pulmonary function and respiratory muscle strength in PD and MSA, and to investigate the association with severity of motor symptoms and disease duration. Pulmonary function and respiratory muscle strength tests were performed in 30 patients with PD, 27 with MSA as well as in 20 age-, sex-, height-, weight-matched normal elderly controls. All the patients underwent United Parkinson's disease rating scale (UPDRS) or united multiple system atrophy rating scale (UMSARS) separately as diagnosed. Vital capacity, forced expiratory volume in 1 second and forced vital capacity decreased, residual volume and ratio of residual volume to total lung capacity increased in both PD and MSA groups compared to controls (p<0.05). Diffusing capacity was decreased in the MSA group, compared with PD and normal elderly control groups (p<0.05). Respiratory muscle strength was lower in both PD and MSA groups than in controls (p<0.05). The values representing spirometry function and respiratory muscle strength were found to have a negative linear correlation with mean score of UPDRS-III in PD and mean score of UMSARS-I in MSA. Respiratory muscle strength showed a negative linear correlation with the mean score of UMSARS-II and disease duration in MSA patients. These findings suggest that respiratory dysfunction is involved in PD and MSA. Respiratory muscle strength is remarkably reduced, and some of the parameters correlate with disease duration and illness severity. The compromised respiratory function in neurodegenerative disorders should be the focus of further researches.

  11. Chemical looping integration with a carbon dioxide gas purification unit

    DOEpatents

    Andrus, Jr., Herbert E.; Jukkola, Glen D.; Thibeault, Paul R.; Liljedahl, Gregory N.

    2017-01-24

    A chemical looping system that contains an oxidizer and a reducer is in fluid communication with a gas purification unit. The gas purification unit has at least one compressor, at least one dryer; and at least one distillation purification system; where the gas purification unit is operative to separate carbon dioxide from other contaminants present in the flue gas stream; and where the gas purification unit is operative to recycle the contaminants to the chemical looping system in the form of a vent gas that provides lift for reactants in the reducer.

  12. 40 CFR 63.1423 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Incinerator (subpart G) Major source (subpart A) Malfunction (subpart A) Oil-water separator or organic-water... process unit consists of more than one unit operation. This collection of equipment includes purification... feed tank drawdown; water formed during a chemical reaction or used as a reactant; water used to wash...

  13. 40 CFR 63.1423 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Incinerator (subpart G) Major source (subpart A) Malfunction (subpart A) Oil-water separator or organic-water... process unit consists of more than one unit operation. This collection of equipment includes purification... feed tank drawdown; water formed during a chemical reaction or used as a reactant; water used to wash...

  14. 40 CFR 63.1423 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Incinerator (subpart G) Major source (subpart A) Malfunction (subpart A) Oil-water separator or organic-water... process unit consists of more than one unit operation. This collection of equipment includes purification... feed tank drawdown; water formed during a chemical reaction or used as a reactant; water used to wash...

  15. 47 CFR 76.71 - Scope of application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... provisions of this subpart shall apply to any corporation, partnership, association, joint-stock company, or..., they shall constitute a single employment unit. (c) Headquarters office. A multiple cable operator shall treat as a separate employment unit each headquarters office to the extent the work of that office...

  16. Teaching a Biotechnology Unit in High School General Biology.

    ERIC Educational Resources Information Center

    Hays, Lana

    1994-01-01

    Describes a unit in biotechnology for average and below average high school students. Students developed productive team membership, used math and communication skills to solve problems, and used the scientific method to learn about biotechnology. Students separated DNA, transformed bacterial cells, interpreted DNA fingerprints, completed creative…

  17. Language and pragmatic functions in school-age children on the autism spectrum.

    PubMed

    Ramberg, C; Ehlers, S; Nydén, A; Johansson, M; Gillberg, C

    1996-01-01

    This study examined group differences in language and pragmatic functions across sex-, age- and IQ-matched samples of Asperger syndrome (N = 22), high-functioning autism (N = 11), deficits in attention, motor control and perception (DAMP) (N = 11), and speech and language disorder (SLD) (N = 11) groups. The purpose was to explore possible differentiating features in the fields of vocabulary, comprehension and pragmatics and, in addition, to determine whether Asperger syndrome could be reliably separated from high-functioning autism on these variables. The findings suggest that Asperger syndrome may be associated with higher full-scale and verbal IQ than high-functioning autism; Asperger syndrome may not be associated with better pragmatic skills (as defined in this context) than high-functioning autism; language comprehension may not clearly separate Asperger syndrome and high-functioning autism once the effects of very low IQ are partialled out; both DAMP and SLD can be distinctly separated from Asperger syndrome and autism.

  18. Development of the Focal Plane Detection System for the Future Gas-Filled Separator at the Cyclotron Institute

    NASA Astrophysics Data System (ADS)

    Bertelsen, Erin; Mayorov, Dmitriy; Folden, Charles ``Cody'', III

    2015-10-01

    A focal plane detection system is being developed for use with the gas-filled separator previously known as SASSYER (Small Angle Separator System at Yale for Evaporation Residues) that will be installed at the Cyclotron Institute at Texas A&M University. This system will be used to study heavy (Z >= 90) elements and features two 60×40 strip double-sided silicon detectors (DSSDs) and accompanying multiplexing read-out electronics. The DSSDs cover an area of 120×40 mm2 and are read-out by fourteen 16-channel multiplexers (Mesytec MUX-16) that perform the function of a preamplifier, shaper, and leading-edge discriminator in one unit. The multiplexers are controlled by four ``MUX drivers,'' each of which serves as a signal bus for multiple MUX-16 boards. The system allows a single 16-channel ADC to read the combined 200 strips of both DSSDs. A four peak source composed of 148Gd, 239Pu, 241Am, and 244Cm was used to characterize the performance of the system, with a preliminary energy resolution of ~ 60 keV measured for the 241Am alphas. This contribution will discuss the work performed in assembly of the test setup, optimization and performance check of the multiplexers, and the preliminary energy and position data collected with the α-source. Present address: Los Alamos National Laboratory, Los Alamos, NM 87545.

  19. Air sampling unit for breath analyzers

    NASA Astrophysics Data System (ADS)

    Szabra, Dariusz; Prokopiuk, Artur; Mikołajczyk, Janusz; Ligor, Tomasz; Buszewski, Bogusław; Bielecki, Zbigniew

    2017-11-01

    The paper presents a portable breath sampling unit (BSU) for human breath analyzers. The developed unit can be used to probe air from the upper airway and alveolar for clinical and science studies. The BSU is able to operate as a patient interface device for most types of breath analyzers. Its main task is to separate and to collect the selected phases of the exhaled air. To monitor the so-called I, II, or III phase and to identify the airflow from the upper and lower parts of the human respiratory system, the unit performs measurements of the exhaled CO2 (ECO2) in the concentration range of 0%-20% (0-150 mm Hg). It can work in both on-line and off-line modes according to American Thoracic Society/European Respiratory Society standards. A Tedlar bag with a volume of 5 dm3 is mounted as a BSU sample container. This volume allows us to collect ca. 1-25 selected breath phases. At the user panel, each step of the unit operation is visualized by LED indicators. This helps us to regulate the natural breathing cycle of the patient. There is also an operator's panel to ensure monitoring and configuration setup of the unit parameters. The operation of the breath sampling unit was preliminarily verified using the gas chromatography/mass spectrometry (GC/MS) laboratory setup. At this setup, volatile organic compounds were extracted by solid phase microextraction. The tests were performed by the comparison of GC/MS signals from both exhaled nitric oxide and isoprene analyses for three breath phases. The functionality of the unit was proven because there was an observed increase in the signal level in the case of the III phase (approximately 40%). The described work made it possible to construct a prototype of a very efficient breath sampling unit dedicated to breath sample analyzers.

  20. Relating Resources to Personnel Readiness. Use of Army Strength Management Models,

    DTIC Science & Technology

    1997-01-01

    far from the resources. In fact, they do not consider them. What they do consider is the historical performance of response variables, using a...hierarchy is the readiness of the force or the ability of the overall force to perform a given mission successfully. A force is composed of units...at the unit level. SORTS pro- duces unit "C-levels" that characterize the proportion of the wartime mission the unit can perform .5 Separate ratings

  1. The load separation technique in the elastic-plastic fracture analysis of two- and three-dimensional geometries

    NASA Technical Reports Server (NTRS)

    Sharobeam, Monir H.

    1994-01-01

    Load separation is the representation of the load in the test records of geometries containing cracks as a multiplication of two separate functions: a crack geometry function and a material deformation function. Load separation is demonstrated in the test records of several two-dimensional geometries such as compact tension geometry, single edge notched bend geometry, and center cracked tension geometry and three-dimensional geometries such as semi-elliptical surface crack. The role of load separation in the evaluation of the fracture parameter J-integral and the associated factor eta for two-dimensional geometries is discussed. The paper also discusses the theoretical basis and the procedure for using load separation as a simplified yet accurate approach for plastic J evaluation in semi-elliptical surface crack which is a three-dimensional geometry. The experimental evaluation of J, and particularly J(sub pl), for three-dimensional geometries is very challenging. A few approaches have been developed in this regard and they are either complex or very approximate. The paper also presents the load separation as a mean to identify the blunting and crack growth regions in the experimental test records of precracked specimens. Finally, load separation as a methodology in elastic-plastic fracture mechanics is presented.

  2. Separation of whole blood into plasma and red cells by using a hollow-fibre filtration system.

    PubMed

    Hornsey, V S; McColl, K; Drummond, O; Prowse, C V

    2005-08-01

    The aim of this study was to assess the separation of whole blood into red cells and plasma by using the Sangofer device, which is a gravity-fed, hollow-fibre system. The components would then be compared with those produced by the use of more elaborate technical equipment. Ten whole-blood units were leucoreduced by using a WBF2 filter and immediately separated into red cells and plasma by using the Sangofer blood-separation device. Red cells were stored in additive solution and tested on days 1 and 42. The plasma was assayed for levels of various coagulation factors and for markers of both coagulation and complement activation. The red-cell parameters were similar to those obtained when routine centrifugation methods were used. The filter did not cause haemolysis. Levels of plasma factor VIII and factor XI were lower than those seen in routinely produced leucoreduced plasma units but there was no evidence of activation of the coagulation and complement systems. The Sangofer device is simple and straightforward to use and eliminates the need for both centrifugation and automated separation steps during the processing of whole blood into red cells and plasma components. Minor changes are required to make the procedure easier to incorporate into routine use.

  3. Simplified thermodynamic functions for vapor-liquid phase separation and fountain effect pumps

    NASA Technical Reports Server (NTRS)

    Yuan, S. W. K.; Hepler, W. A.; Frederking, T. H. K.

    1984-01-01

    He-4 fluid handling devices near 2 K require novel components for non-Newtonian fluid transport in He II. Related sizing of devices has to be based on appropriate thermophysical property functions. The present paper presents simplified equilibrium state functions for porous media components which serve as vapor-liquid phase separators and fountain effect pumps.

  4. On the Relativistic Separable Functions for the Breakup Reactions

    NASA Astrophysics Data System (ADS)

    Bondarenko, Serge G.; Burov, Valery V.; Rogochaya, Elena P.

    2018-02-01

    In the paper the so-called modified Yamaguchi function for the Bethe-Salpeter equation with a separable kernel is discussed. The type of the functions is defined by the analytic stucture of the hadron current with breakup - the reactions with interacting nucleon-nucleon pair in the final state (electro-, photo-, and nucleon-disintegration of the deuteron).

  5. The Study of Programs of Instruction for Handicapped Children and Youth in Day and Residential Facilities. Volume IV. Survey Instruments and Materials for the Survey of Separate Facilities and the Survey of SEA Special Education Divisions.

    ERIC Educational Resources Information Center

    Stephens, Susan A.; Lakin, K. Charlie

    This document, the fourth of five volumes of a study of programs of instruction for handicapped children and youth in separate day and residential facilities throughout the United States, contains instruments and materials used in two surveys designed to gather data for the study: (1) a survey of separate facilities; and (2) a survey of State…

  6. Army National Guard and Army Reserve: Enlisted Administrative Separations

    DTIC Science & Technology

    2001-12-03

    this case is the largest separate unit prescribed by the TOE or TDA. Unsatisfactory participant A member of the Selected or individual Ready Reserve...unless a mental status evaluation is required by this regulation (para 1-8a) and the reason for separation is not based on the soldier’s mental status...revises previous chapter 5 and is currently chapter 8 in new revision. o AR 135-178 is governed by DOD Directive 1332.14, and to ensure compliance and

  7. AZEOTROPIC RECTIFICATION OF A MIXTURE OF SILICON TETRACHLORIDE WITH TRIMETHYLCHLOROSILANE IN THE PRESENCE OF ACETONITRILE,

    DTIC Science & Technology

    Batch and continuous units are described for separating binary azeotropes consisting of SiCl4 plus acetonitrile(CH3CN) (b.p. 49.1C) and (CH3)3SiCl...separated from the crude SiCl4 and (CH3)3SiCl mixture. In the second and third, SiCl4 and (CH3) 3SiCl are separated. The experimental results were in close agreement (9 to 12 percent deviation) with those calculated. (Author)

  8. Thermophoretic separation of aerosol particles from a sampled gas stream

    DOEpatents

    Postma, A.K.

    1984-09-07

    This disclosure relates to separation of aerosol particles from gas samples withdrawn from within a contained atmosphere, such as containment vessels for nuclear reactors or other process equipment where remote gaseous sampling is required. It is specifically directed to separation of dense aerosols including particles of any size and at high mass loadings and high corrosivity. The United States Government has rights in this invention pursuant to Contract DE-AC06-76FF02170 between the US Department of Energy and Westinghouse Electric Corporation.

  9. Development of hydrologic landscape regions for classifying hydrologic permanace and hydrological-ecological interactions

    EPA Science Inventory

    In a 2001 paper, Winter proposed the concept of the hydrologic landscape unit as a fundamental unit composed of an upland and lowland separated by a steeper slope. Winter suggested that this concept could be useful for hydrologic research, data analysis, and comparing hydrologic...

  10. Food Processing Curriculum Material and Resource Guide.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge.

    Intended for secondary vocational agriculture teachers, this curriculum guide contains a course outline and a resource manual for a seven-unit food processing course on meats. Within the course outline, units are divided into separate lessons. Materials provided for each lesson include preparation for instruction (student objectives, review of…

  11. Personnel Development for Entrepreneurs.

    ERIC Educational Resources Information Center

    Sanders, Leon; And Others

    Divided into three units, this curriculum guide on entrepreneur education covers nineteen individual areas of instruction and can be conducted in a series of nine workshops. (The development, field testing, and evaluation of the curriculum are reported separately as CE 015 581.) Unit I covers the following areas of instruction: planning,…

  12. Trade Masonry Syllabus.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Occupational Education Curriculum Development.

    Designed for a two-year course of study, this syllabus encompasses six areas of the masonry trade: concrete, block, brick, stone, tile, and plaster. For each area, the separate units of instruction contain course content outline, student behavioral objectives, and suggested teaching methods and audiovisuals. The six sections and their units are as…

  13. Preferred Styles of Conflict Resolution. Mexico and the United States.

    ERIC Educational Resources Information Center

    Gabrielidis, Cristina; Stephan, Walter G.; Ybarra, Oscar; Pearson, Virginia Dos Santos; Villareal, Lucila

    1997-01-01

    Examined cultural differences in preferences for conflict resolution styles using the dual-concern model with 103 college students in Mexico (collectivistic culture) and 91 college students in the United States (individualistic culture). Results suggest that independence of the self and interdependence of the self may be separate dimensions,…

  14. 50 Ways to Supplement Housing and Home Furnishings.

    ERIC Educational Resources Information Center

    Sawatzky, Joyce

    This publication presents classroom instructional materials in separate units for use in teaching and implementing a housing and home furnishings component in the home economics curriculum at the secondary level. Units given are included for living space design; living space and human needs; housing selection; home finance; construction and…

  15. Energy Drinks. Prevention Update

    ERIC Educational Resources Information Center

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2010

    2010-01-01

    High-caffeine soft drinks have existed in the United States since at least the 1980s beginning with Jolt Cola. Energy drinks, which have caffeine as their primary "energy" component, began being marketed as a separate beverage category in the United States in 1997 with the introduction of the Austrian import Red Bull. Energy drink…

  16. Participation in International Large-Scale Assessments from a US Perspective

    ERIC Educational Resources Information Center

    Plisko, Valena White

    2013-01-01

    International large-scale assessments (ILSAs) play a distinct role in the United States' decentralized federal education system. Separate from national and state assessments, they offer an external, objective measure for the United States to assess student performance comparatively with other countries and over time. The US engagement in ILSAs…

  17. 7 CFR 52.804 - Ascertaining the grade of a sample unit.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... pitted cherries is determined immediately after thawing to the extent that the cherries may be separated... 7 Agriculture 2 2011-01-01 2011-01-01 false Ascertaining the grade of a sample unit. 52.804 Section 52.804 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE...

  18. International Reports on Literacy Research: France, United Kingdom, Brazil

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botza, Stergios, Comp.

    2005-01-01

    This is a compilation of reports on international literacy research. The report includes 3 separate reports on France, United Kingdom and Brazil. In the first report, research correspondent Jacques Fijalkow presents research into variations of reading motivation related to students' socioeconomic status (SES), age, and gender. Three of these…

  19. Energy Theme.

    ERIC Educational Resources Information Center

    Garrahy, Dennis J.

    One of a series of social studies units designed to develop the reading and writing skills of low achievers, this student activity book focuses on the theme of energy. The unit can be used for high school classes, individual study in alternative and continuing high schools, and adult education classes. Separate sections cover early sources of…

  20. Selective oxoanion separation using a tripodal ligand

    DOEpatents

    Custelcean, Radu; Moyer, Bruce A.; Rajbanshi, Arbin

    2016-02-16

    The present invention relates to urea-functionalized crystalline capsules self-assembled by sodium or potassium cation coordination and by hydrogen-bonding water bridges to selectively encapsulate tetrahedral divalent oxoanions from highly competitive aqueous alkaline solutions and methods using this system for selective anion separations from industrial solutions. The method involves competitive crystallizations using a tripodal tris(urea) functionalized ligand and, in particular, provides a viable approach to sulfate separation from nuclear wastes.

  1. On the detection of functionally coherent groups of protein domains with an extension to protein annotation

    PubMed Central

    McLaughlin, William A; Chen, Ken; Hou, Tingjun; Wang, Wei

    2007-01-01

    Background Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available methods to identify functional domain combinations are limited in their scope, e.g. to the identification of combinations falling within individual proteins or within specific regions in a translated genome. Further effort is needed to identify groups of domains that span across two or more proteins and are linked by a cooperative function. Such functional domain combinations can be useful for protein annotation. Results Using a new computational method, we have identified 114 groups of domains, referred to as domain assembly units (DASSEM units), in the proteome of budding yeast Saccharomyces cerevisiae. The units participate in many important cellular processes such as transcription regulation, translation initiation, and mRNA splicing. Within the units the domains were found to function in a cooperative manner; and each domain contributed to a different aspect of the unit's overall function. The member domains of DASSEM units were found to be significantly enriched among proteins contained in transcription modules, defined as genes sharing similar expression profiles and presumably similar functions. The observation further confirmed the functional coherence of DASSEM units. The functional linkages of units were found in both functionally characterized and uncharacterized proteins, which enabled the assessment of protein function based on domain composition. Conclusion A new computational method was developed to identify groups of domains that are linked by a common function in the proteome of Saccharomyces cerevisiae. These groups can either lie within individual proteins or span across different proteins. We propose that the functional linkages among the domains within the DASSEM units can be used as a non-homology based tool to annotate uncharacterized proteins. PMID:17937820

  2. Revised hydrogeologic framework of the Floridan aquifer system in the northern coastal area of Georgia and adjacent parts of South Carolina

    USGS Publications Warehouse

    Williams, Lester J.; Gill, Harold E.

    2010-01-01

    The hydrogeologic framework for the Floridan aquifer system has been revised for eight northern coastal counties in Georgia and five coastal counties in South Carolina by incorporating new borehole geophysical and flowmeter log data collected during previous investigations. Selected well logs were compiled and analyzed to determine the vertical and horizontal continuity of permeable zones that make up the Upper and Lower Floridan aquifers and to define more precisely the thickness of confining beds that separate these aquifers. The updated framework generally conforms to the original framework established by the U.S. Geological Survey in the 1980s except for adjustments made to the internal boundaries of the Upper and Lower Floridan aquifers and the individual permeable zones that compose these aquifers. The revised boundaries of the Floridan aquifer system were mapped by taking into account results from local studies and regional correlations of geologic and hydrogeologic units. Because the revised framework does not match the previous regional framework along all edges, additional work will be needed to expand the framework into adjacent areas. The Floridan aquifer system in the northern coastal region of Georgia and parts of South Carolina can be divided into the Upper and Lower Floridan aquifers, which are separated by a middle confining unit of relatively lower permeability. The Upper Floridan aquifer includes permeable and hydraulically connected carbonate rocks of Oligocene and upper Eocene age that represent the most transmissive part of the aquifer system. The middle confining unit consists of low permeability carbonate rocks that lie within the lower part of the upper Eocene in Beaufort and Jasper Counties, South Carolina, and within the upper to middle parts of the middle Eocene elsewhere. Locally, the middle confining unit contains thin zones that have moderate to high permeability and can produce water to wells that tap them. The Lower Floridan aquifer includes all permeable strata that lie below the middle confining unit and above the base of the aquifer system. Beneath Hilton Head Island, South Carolina, the middle Floridan aquifer is now included as part of the Lower Floridan aquifer. The base of the Floridan aquifer system generally is located at the top of lower Eocene rocks in Georgia and the top of Paleocene rocks in South Carolina. The Upper and Lower Floridan aquifers are interconnected to varying degrees depending on the thickness and permeability of the middle confining unit that separates these aquifers. In most places, hydraulic head differences between the two aquifers range from a few inches to a few feet or more. Monitoring at several vertically clustered well-point sites where wells were set at different depths in the aquifer revealed variations in the degree of hydraulic separation with depth. In general, the head separation between the Upper and Lower Floridan aquifers increases with depth, which indicates that the deeper zones are more hydraulically separated than the shallower parts of the Lower Floridan aquifer.

  3. Color- and motion-specific units in the tectum opticum of goldfish.

    PubMed

    Gruber, Morna; Behrend, Konstantin; Neumeyer, Christa

    2016-01-05

    Extracellular recordings were performed from 69 units at different depths between 50 and [Formula: see text]m below the surface of tectum opticum in goldfish. Using large field stimuli (86[Formula: see text] visual angle) of 21 colored HKS-papers we were able to record from 54 color-sensitive units. The colored papers were presented for 5[Formula: see text]s each. They were arranged in the sequence of the color circle in humans separated by gray of medium brightness. We found 22 units with best responses between orange, red and pink. About 12 of these red-sensitive units were of the opponent "red-ON/blue-green-OFF" type as found in retinal bipolar- and ganglion cells as well. Most of them were also activated or inhibited by black and/or white. Some units responded specifically to red either with activation or inhibition. 18 units were sensitive to blue and/or green, 10 of them to both colors and most of them to black as well. They were inhibited by red, and belonged to the opponent "blue-green-ON/red-OFF" type. Other units responded more selectively either to blue, to green or to purple. Two units were selectively sensitive to yellow. A total of 15 units were sensitive to motion, stimulated by an excentrically rotating black and white random dot pattern. Activity of these units was also large when a red-green random dot pattern of high L-cone contrast was used. Activity dropped to zero when the red-green pattern did not modulate the L-cones. Neither of these motion selective units responded to any color. The results directly show color-blindness of motion vision, and confirm the hypothesis of separate and parallel processing of "color" and "motion".

  4. Structural violence and marginalisation. The sexual and reproductive health experiences of separated young people on the move. A rapid review with relevance to the European humanitarian crisis.

    PubMed

    Mason-Jones, A J; Nicholson, P

    2018-05-01

    To explore the main sexual and reproductive health (SRH) issues for separated young migrants. We conducted a rapid review. The search for articles published between 2000 and June 2017 including peer-reviewed and 'grey' published literature from a range of databases including MEDLINE, AMED, Embase, ASSIA, Scopus, Web of Science and websites of international organisations (Missing Children Alliance, United Nations Population Fund (UNFPA), World Health Organization (WHO), United Nations Human Rights Council (UNHRC), Human Rights Watch, United Nations Children's Fund (UNICEF) and FBX Centre for Health and Human Rights) took place over 4 months. Themes emerging from the included studies and articles were synthesised. We found 44 articles from a range of countries of which 64% were peer-reviewed and 36% were from 'grey' literature. Structural violence and marginalisation were the key analytical themes that emerged and included young people's vulnerability to violence, unmet knowledge and service needs, barriers and stigma and poor SRH outcomes. This is the first known review to summarise the key SRH issues for separated young migrants. As Europe hosts the greatest number of separated young people in recent history, their unique SRH concerns risk being overlooked. Public health practitioners and policy makers are encouraged to challenge the gaps that exist in their services. Copyright © 2018 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  5. Substituted polyacetylene separation membrane

    DOEpatents

    Pinnau, Ingo; Morisato, Atsushi

    1998-01-13

    A separation membrane useful for gas separation, particularly separation of C.sub.2+ hydrocarbons from natural gas. The invention encompasses the membrane itself, methods of making it and processes for using it. The membrane comprises a polymer having repeating units of a hydrocarbon-based, disubstituted polyacetylene, having the general formula: ##STR1## wherein R.sub.1 is chosen from the group consisting of C.sub.1 -C.sub.4 alkyl and phenyl, and wherein R.sub.2 is chosen from the group consisting of hydrogen and phenyl. In the most preferred embodiment, the membrane comprises poly(4-methyl-2-pentyne) ›PMP!. The membrane exhibits good chemical resistance and has super-glassy properties with regard to separating certain large, condensable permeant species from smaller, less-condensable permeant species. The membranes may also be useful in other fluid separations.

  6. Magnetic separation anxiety

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Canning, C.

    1992-01-01

    This paper reports that only a few years ago superconducting magnetic separation was viewed as the next major market for superconducting magnets. The first commercial units had been installed, worked flawlessly, and demonstrated real economic viability. The potential market was seen as quite large, and many people believed that superconducting magnetic separation would soon show the same rapid growth that MRI had demonstrated after its initial success. These hopes even prompted IGC, one of the top MRI magnet builders, to form a separate division devoted to magnetic separation. Despite the existence of Magstream, IGC has not been overly active inmore » the market. As a technology that has applications from the clay on the Earth to the soil on the moon, superconducting magnetic separation has yet to become widely used.« less

  7. Reconfigurable Fault Tolerance for FPGAs

    NASA Technical Reports Server (NTRS)

    Shuler, Robert, Jr.

    2010-01-01

    The invention allows a field-programmable gate array (FPGA) or similar device to be efficiently reconfigured in whole or in part to provide higher capacity, non-redundant operation. The redundant device consists of functional units such as adders or multipliers, configuration memory for the functional units, a programmable routing method, configuration memory for the routing method, and various other features such as block RAM, I/O (random access memory, input/output) capability, dedicated carry logic, etc. The redundant device has three identical sets of functional units and routing resources and majority voters that correct errors. The configuration memory may or may not be redundant, depending on need. For example, SRAM-based FPGAs will need some type of radiation-tolerant configuration memory, or they will need triple-redundant configuration memory. Flash or anti-fuse devices will generally not need redundant configuration memory. Some means of loading and verifying the configuration memory is also required. These are all components of the pre-existing redundant FPGA. This innovation modifies the voter to accept a MODE input, which specifies whether ordinary voting is to occur, or if redundancy is to be split. Generally, additional routing resources will also be required to pass data between sections of the device created by splitting the redundancy. In redundancy mode, the voters produce an output corresponding to the two inputs that agree, in the usual fashion. In the split mode, the voters select just one input and convey this to the output, ignoring the other inputs. In a dual-redundant system (as opposed to triple-redundant), instead of a voter, there is some means to latch or gate a state update only when both inputs agree. In this case, the invention would require modification of the latch or gate so that it would operate normally in redundant mode, and would separately latch or gate the inputs in non-redundant mode.

  8. Supramolecular ribbons from amphiphilic trisamides self-assembly.

    PubMed

    García, Fátima; Buendía, Julia; Sánchez, Luis

    2011-08-05

    Two amphiphilic C(3)-symmetric OPE-based trisamides have been synthesized and their self-assembling features investigated in solution and on surface. Variable-temperature UV-vis experiments demonstrate the cooperative supramolecular polymerization of these trisamides that self-assemble by the operation of triple C═O···H-N H-bonding arrays between the amide functional groups and π-π stacking between the aromatic units. The helical organization of the aggregates has been demonstrated by circular dichroism at a concentration as low as 1 × 10(-4) M in acetonitrile. In the reported trisamides, the large hydrophobic aromatic core acts as a solvophobic module impeding the interaction between the polar TEG chains and the amide H-bonds. This strategy makes unnecessary the separation of the amide functional groups to the polar tri(ethylene glycol) chains by paraffinic fragments. Achiral trisamide 1 self-assembles into flat ribbon-like structures that experience an amplification of chirality by the addition of a small amount of chiral 2 that generates twisted stripes.

  9. Radiation from long pulse train electron beams in space plasmas

    NASA Technical Reports Server (NTRS)

    Harker, K. J.; Banks, P. M.

    1985-01-01

    A previous study of electromagnetic radiation from a finite train of electron pulses is extended to an infinite train of such pulses. The electrons are assumed to follow an idealized helical path through a space plasma in such a manner as to retain their respective position within the beam. This leads to radiation by coherent spontaneous emission. The waves of interest in this region are the whistler slow (compressional) and fast (torsional) Alfven waves. Although a general theory is developed, analysis is then restricted to two approximations, the short and long electron beam. Formulas for the radiation per unit solid angle from the short beam are presented as a function of both propagation and ray angles, electron beam pulse width and separation and beam current, voltage, and pitch angle. Similar formulas for the total power radiated from the long beam are derived as a function of frequency, propagation angle, and ray angle. Predictions of the power radiated are presented for representative examples as determined by the long beam theory.

  10. ISAP: ISO Spectral Analysis Package

    NASA Astrophysics Data System (ADS)

    Ali, Babar; Bauer, Otto; Brauher, Jim; Buckley, Mark; Harwood, Andrew; Hur, Min; Khan, Iffat; Li, Jing; Lord, Steve; Lutz, Dieter; Mazzarella, Joe; Molinari, Sergio; Morris, Pat; Narron, Bob; Seidenschwang, Karla; Sidher, Sunil; Sturm, Eckhard; Swinyard, Bruce; Unger, Sarah; Verstraete, Laurent; Vivares, Florence; Wieprecht, Ecki

    2014-03-01

    ISAP, written in IDL, simplifies the process of visualizing, subsetting, shifting, rebinning, masking, combining scans with weighted means or medians, filtering, and smoothing Auto Analysis Results (AARs) from post-pipeline processing of the Infrared Space Observatory's (ISO) Short Wavelength Spectrometer (SWS) and Long Wavelength Spectrometer (LWS) data. It can also be applied to PHOT-S and CAM-CVF data, and data from practically any spectrometer. The result of a typical ISAP session is expected to be a "simple spectrum" (single-valued spectrum which may be resampled to a uniform wavelength separation if desired) that can be further analyzed and measured either with other ISAP functions, native IDL functions, or exported to other analysis package (e.g., IRAF, MIDAS) if desired. ISAP provides many tools for further analysis, line-fitting, and continuum measurements, such as routines for unit conversions, conversions from wavelength space to frequency space, line and continuum fitting, flux measurement, synthetic photometry and models such as a zodiacal light model to predict and subtract the dominant foreground at some wavelengths.

  11. Simultaneous Semi-Distributed Model Calibration Guided by ...

    EPA Pesticide Factsheets

    Modelling approaches to transfer hydrologically-relevant information from locations with streamflow measurements to locations without such measurements continues to be an active field of research for hydrologists. The Pacific Northwest Hydrologic Landscapes (PNW HL) provide a solid conceptual classification framework based on our understanding of dominant processes. A Hydrologic Landscape code (5 letter descriptor based on physical and climatic properties) describes each assessment unit area, and these units average area 60km2. The core function of these HL codes is to relate and transfer hydrologically meaningful information between watersheds without the need for streamflow time series. We present a novel approach based on the HL framework to answer the question “How can we calibrate models across separate watersheds simultaneously, guided by our understanding of dominant processes?“. We should be able to apply the same parameterizations to assessment units of common HL codes if 1) the Hydrologic Landscapes contain hydrologic information transferable between watersheds at a sub-watershed-scale and 2) we use a conceptual hydrologic model and parameters that reflect the hydrologic behavior of a watershed. In this study, This work specifically tests the ability or inability to use HL-codes to inform and share model parameters across watersheds in the Pacific Northwest. EPA’s Western Ecology Division has published and is refining a framework for defining la

  12. Therapist turnover and new program sustainability in mental health clinics as a function of organizational culture, climate, and service structure.

    PubMed

    Glisson, Charles; Schoenwald, Sonja K; Kelleher, Kelly; Landsverk, John; Hoagwood, Kimberly Eaton; Mayberg, Stephen; Green, Philip

    2008-03-01

    The present study incorporates organizational theory and organizational characteristics in examining issues related to the successful implementation of mental health services. Following the theoretical foundations of socio-technical and cultural models of organizational effectiveness, organizational climate, culture, legal and service structures, and workforce characteristics are examined as correlates of therapist turnover and new program sustainability in a nationwide sample of mental health clinics. Results of General Linear Modeling (GLM) with the organization as the unit of analysis revealed that organizations with the best climates as measured by the Organizational Social Context (OSC) profiling system, had annual turnover rates (10%) that were less than half the rates found in organizations with the worst climates (22%). In addition, organizations with the best culture profiles sustained new treatment or service programs over twice as long (50 vs. 24 months) as organizations with the worst cultures. Finally, clinics with separate children's services units had higher turnover rates than clinics that served adults and children within the same unit. The findings suggest that strategies to support the implementation of new mental health treatments and services should attend to organizational culture and climate, and to the compatibility of organizational service structures with the demand characteristics of treatments.

  13. The diatom genus Actinocyclus in the Western United States

    USGS Publications Warehouse

    Bradbury, J. Platt; Krebs, William N.; Bradbury, J. Platt; Krebs, William N.

    1995-01-01

    Ten new and four known taxa of the diatom genus Actinocyclus are described, illustrated, and (or) noted from middle Miocene lake deposits in the Western United States. A key is presented to help separate the taxa based on morphological criteria visible in the light microscope. The geologic ranges of Actinocyclus species in the Western United States are discussed based on examination of over 100 localities of diatomaceous lacustrine deposits.

  14. Parent-Child Separation: A Comparison of Maternally and Paternally Separated Children in Military Families.

    ERIC Educational Resources Information Center

    Applewhite, Larry W.; Mays, Robert A.

    1996-01-01

    Claims that children of parents in the military services have adapted to parental separation as parents balance the demands of family and job responsibility. Compares the psychosocial functioning of children who have experienced extended maternal separation with that exhibited by children who have separated from their fathers. Addresses…

  15. Functional Allocation with Airborne Self-Separation Evaluated in a Piloted Simulation

    NASA Technical Reports Server (NTRS)

    Wing, David J.; Murdoch, Jennifer L.; Chamberlain, James P.; Consiglio, Maria C.; Hoardley, Sherwood T.; Hubbs, Clay E.; Palmer, Michael T.

    2010-01-01

    A human-in-the-loop simulation experiment was designed and conducted to evaluate an airborne self-separation concept. The activity supports the National Aeronautics and Space Administration s (NASA) research focus on function allocation for separation assurance. The objectives of the experiment were twofold: (1) use experiment design features in common with a companion study of ground-based automated separation assurance to promote comparability, and (2) assess agility of self-separation operations in managing trajectory-changing events in high traffic density, en-route operations with arrival time constraints. This paper describes the experiment and presents initial results associated with subjective workload ratings and group discussion feedback obtained from the experiment s commercial transport pilot participants.

  16. How to promote and preserve eyelid health.

    PubMed

    Benitez-Del-Castillo, Jose M

    2012-01-01

    Disorders of the lacrimal functional unit are common in ophthalmological practice, with meibomian gland dysfunction, blepharitis, and dry eye forming a significant part of the general ophthalmologist's practice. The eyelid and its associated structures form a complex organ designed to protect the fragile corneal surface and improve visual acuity. This organ is subject to a number of disorders, including meibomian gland dysfunction, dry eye syndrome, anterior blepharitis, allergic and dermatological conditions, and disorders associated with contact lens use. Although commonly described separately, disorders of the lacrimal function unit are better considered as a group of interacting pathologies that have inflammatory mediators as a central feature. Eyelid hygiene, in the sense of routine cleansing and massage of the eyelids, is well accepted in the management of many disorders of the eyelid. However, a broader concept of eyelid health may be appropriate, in which eyelid cleansing is but a part of a more complete program of care that includes screening and risk assessment, patient education, and coaching. The ophthalmologist has an important role to play in helping patients persist with routine eyelid care that may be long-term or lifelong. A number of preparations exist to make routine eyelid care both more effective and more pleasant, and might also improve compliance. Several such preparations have been devised, and are being assessed in clinical studies, and appear to be effective and preferred by patients over traditional soap and water or baby shampoo.

  17. Parallel charge sheets of electron liquid and gas in La0.5Sr0.5TiO3/SrTiO3 heterostructures

    PubMed Central

    Renshaw Wang, X.; Sun, L.; Huang, Z.; Lü, W. M.; Motapothula, M.; Annadi, A.; Liu, Z. Q.; Zeng, S. W.; Venkatesan, T.; Ariando

    2015-01-01

    We show here a new phenomenon in La0.5Sr0.5TiO3/SrTiO3 (LSTO/STO) heterostructures; that is a coexistence of three-dimensional electron liquid (3DEL) and 2D electron gas (2DEG), separated by an intervening insulating LSTO layer. The two types of carriers were revealed through multi-channel analysis of the evolution of nonlinear Hall effect as a function of film thickness, temperature and back gate voltage. We demonstrate that the 3D electron originates from La doping in LSTO film and the 2D electron at the surface of STO is due to the polar field in the intervening insulating layer. As the film thickness is reduced below a critical thickness of 6 unit cells (uc), an abrupt metal-to-insulator transition (MIT) occurs without an intermediate semiconducting state. The properties of the LSTO layer grown on different substrates suggest that the insulating phase of the intervening layer is a result of interface strain induced by the lattice mismatch between the film and substrate. Further, by fitting the magnetoresistance (MR) curves, the 6 unit cell thick LSTO is shown to exhibit spin-orbital coupling. These observations point to new functionalities, in addition to magnetism and superconductivity in STO-based systems, which could be exploited in a multifunctional context. PMID:26669575

  18. Drinking-water arsenic exposure modulates gene expression in human lymphocytes from a U.S. population.

    PubMed

    Andrew, Angeline S; Jewell, David A; Mason, Rebecca A; Whitfield, Michael L; Moore, Jason H; Karagas, Margaret R

    2008-04-01

    Arsenic exposure impairs development and can lead to cancer, cardiovascular disease, and diabetes. The mechanism underlying these effects remains unknown. Primarily because of geologic sources of contamination, drinking-water arsenic levels are above the current recommended maximum contaminant level of 10 microg/L in the northeastern, western, and north central regions of the United States. We investigated the effects of arsenic exposure, defined by internal biomarkers at levels relevant to the United States and similarly exposed populations, on gene expression. We conducted separate Affymetrix microarray-based genomewide analyses of expression patterns. Peripheral blood lymphocyte samples from 21 controls interviewed (1999-2002) as part of a case-control study in New Hampshire were selected based on high- versus low-level arsenic exposure levels. The biologic functions of the transcripts that showed statistically significant abundance differences between high- and low-arsenic exposure groups included an overrepresentation of genes involved in defense response, immune function, cell growth, apoptosis, regulation of cell cycle, T-cell receptor signaling pathway, and diabetes. Notably, the high-arsenic exposure group exhibited higher levels of several killer cell immunoglobulin-like receptors that inhibit natural killer cell activity. These findings define biologic changes that occur with chronic arsenic exposure in humans and provide leads and potential targets for understanding and monitoring the pathogenesis of arsenic-induced diseases.

  19. Distribution of dopant ions around poly(3,4-ethylenedioxythiophene) chains: a theoretical study.

    PubMed

    Casanovas, Jordi; Zanuy, David; Alemán, Carlos

    2017-04-12

    The effect of counterions and multiple polymer chains on the properties and structure of poly(3,4-ethylenedioxythiophene) (PEDOT) doped with ClO 4 - has been examined using density functional theory (DFT) calculations with periodic boundary conditions (PBCs). Calculations on a one-dimensional periodic model with four explicit polymer repeat units and two ClO 4 - molecules indicate that the latter are separated as much as possible, with the salt structure and band gap obtained from such ClO 4 - distribution being in excellent agreement with those determined experimentally. On the other hand, DFT calculations on periodic models that include two chains indicate that neighboring PEDOT chains are shifted along the molecular axis by a half of the repeat unit length, with dopant ions intercalated between the polymer molecules acting as cement. In order to support these structural features, classical molecular dynamics (MD) simulations have been performed on a multiphasic system consisting of 69 explicit PEDOT chains anchored onto a steel surface, explicit ClO 4 - anions embedded in the polymer matrix, and an acetonitrile phase layer onto the polymer matrix. Analyses of the radial distribution functions indicate that the all-anti conformation, the relative disposition of adjacent PEDOT chains and the distribution of ClO 4 - dopant ions are fully consistent with periodic DFT predictions. The agreement between two such different methodologies allows reinforcing the microscopic understanding of the PEDOT film structure.

  20. Improved density discrimination using agfacontour film

    NASA Technical Reports Server (NTRS)

    Goodding, R. A.

    1973-01-01

    A technique was developed for obtaining tone separations from black and white photographic materials. Agfacontour film and photographic derivatives are utilized to improve the density discrimination and decrease the density range from 0.45 to 0.08 units. This increase in capability extends the usefulness of tone separations to a wider range of subject matter and problem areas.

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