Science.gov

Sample records for service line replacement

  1. 40 CFR 141.84 - Lead service line replacement requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Lead service line replacement... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead service line replacement requirements. (a) Systems that fail to meet the lead action level in tap samples...

  2. 40 CFR 141.84 - Lead service line replacement requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 23 2014-07-01 2014-07-01 false Lead service line replacement requirements. 141.84 Section 141.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84...

  3. 40 CFR 141.84 - Lead service line replacement requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84 Lead... lead levels in their drinking water, along with guidance on measures consumers can take to minimize...) Any water system resuming a lead service line replacement program after the cessation of its...

  4. Science Advisory Board Evaluation of the Effectiveness of Partial Lead Service Line Replacements

    EPA Pesticide Factsheets

    Report of the Science Advisory Board (SAB) to evaluate the current scientific data to determine the effectiveness of partial lead service line replacements (PLSLR) in reducing drinking water lead levels.

  5. Long-Term Behavior of Simulated Partial Lead Service Line Replacements

    PubMed Central

    St. Clair, Justin; Cartier, Clement; Triantafyllidou, Simoni; Clark, Brandi; Edwards, Marc

    2016-01-01

    Abstract In this 48-month pilot study, long-term impacts of copper:lead galvanic connections on lead release to water were assessed without confounding differences in pipe exposure prehistory or disturbances arising from cutting lead pipe. Lead release was tracked from three lead service line configurations, including (1) 100% lead, (2) traditional partial replacement with 50% copper upstream of 50% lead, and (3) 50% lead upstream of 50% copper as a function of flow rate, connection types, and sampling methodologies. Elevated lead from galvanic corrosion worsened with time, with 140% more lead release from configurations representing traditional partial replacement configurations at 14 months compared to earlier data in the first 8 months. Even when sampled consistently at moderate flow rate (8 LPM) and collecting all water passing through service lines, conditions representing traditional partial service line configurations were significantly worse (≈40%) when compared to 100% lead pipe. If sampled at a high flow rate (32 LPM) and collecting 2 L samples from service lines, 100% of samples collected from traditional partial replacement configurations exceeded thresholds posing an acute health risk versus a 0% risk for samples from 100% lead pipe. Temporary removal of lead accumulations near Pb:Cu junctions and lead deposits from other downstream plastic pipes reduced risk of partial replacements relative to that observed for 100% lead. When typical brass compression couplings were used to connect prepassivated lead pipes, lead release spiked up to 10 times higher, confirming prior concerns raised at bench and field scale regarding adverse impacts of crevices and service line disturbances on lead release. To quantify semirandom particulate lead release from service lines in future research, whole-house filters have many advantages compared to other approaches. PMID:26989344

  6. Impact of treatment on Pb release from full and partially replaced harvested Lead Service Lines (LSLs).

    PubMed

    Cartier, Clément; Doré, Evelyne; Laroche, Laurent; Nour, Shokoufeh; Edwards, Marc; Prévost, Michèle

    2013-02-01

    Release of lead from 80% partially replaced service lines was compared to full lead service lines using harvested-stabilized lead pipes and field brass connectors. After more than a year of stabilization, lead release was consistent with field samples. Over the relatively short duration partial replacement of lead pipe by copper pipe (3 months), generated high lead release, attributed to galvanic corrosion, resulting in a final outcome for lead release that was even worse than for a full lead pipe. Increased lead release was especially evident at higher flow rates. Orthophosphate reduced lead release from full lead pipes by 64%. For partially replaced samples with copper, lead concentrations were unchanged by phosphate dosing at moderate flow (103 ± 265 vs 169 ± 349 μg/L) and were increased to very high levels when sampled at high flow rates (1001 ± 1808 vs 257 ± 224 μg/L). The increase lead release was in the form of particulate lead (>90%). In comparison to the condition without treatment, increased sulfate treatment had little impact on lead release from 100%-Pb rigs but reduced lead release from partially replaced lead pipes with copper. Our results also raise questions concerning protocols based on short 30 min stagnation (as those used in Canada) due to their incapacity to consider particulate lead release generated mostly after longer stagnation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Comparison of three corrosion inhibitors in simulated partial lead service line replacements.

    PubMed

    Kogo, Aki; Payne, Sarah Jane; Andrews, Robert C

    2017-05-05

    Partial lead service line replacements (PLSLR) were simulated using five recirculating pipe loops treated with either zinc orthophosphate (1mg/L as P), orthophosphate (1mg/L as P) or sodium silicate (10mg/L). Two pipe loops served as ⿿inhibitor-free⿿ (Pb-Cu) and ⿿galvanic free⿿ (Pb-PVC) controls. Changes in water quality (CSMR [0.2 or 1], conductivity [⿿330mS/cm or ⿿560mS/cm], chlorine [1.4mg/L]) were not observed to provide a significant impact on lead or copper release, although galvanic corrosion was shown to be a driving factor. Generally, both orthophosphate and zinc orthophosphate provided better corrosion control for both total and dissolved lead (30min, 6h, 65h) and copper (30min, 6h), when compared to either the inhibitor-free control or the sodium silicate treated system. This work highlights the importance of understanding the complex interplay of corrosion inhibitors on particulate and dissolved species when considering both lead and copper.

  8. Impact of water quality change on corrosion scales in full and partially replaced lead service lines

    EPA Science Inventory

    BackgroundChanges in water qualities have been associated with an increase in lead release from full and partial lead service lines (LSLs), such as the cases of Washington D.C. or more recently of Flint (Mi). Water qualities affect the mineralogy of the scales. Furthermore, follo...

  9. Impact of water quality change on corrosion scales in full and partially replaced lead service lines

    EPA Science Inventory

    BackgroundChanges in water qualities have been associated with an increase in lead release from full and partial lead service lines (LSLs), such as the cases of Washington D.C. or more recently of Flint (Mi). Water qualities affect the mineralogy of the scales. Furthermore, follo...

  10. Evaluating the Effects of Full and Partial Lead Service Line Replacement on Lead Levels in Drinking Water.

    PubMed

    Trueman, Benjamin F; Camara, Eliman; Gagnon, Graham A

    2016-07-19

    Lead service line replacement (LSLR) is an important strategy for reducing lead exposure via drinking water, but jurisdictional issues can sometimes interfere with full replacement of the lead line. The effects of full and partial LSLR on lead levels were assessed using 5 × 1-L sample profiles collected at more than 100 single-unit residences. Profiles comprised four sequential standing samples (L1-L4) and a free-flowing sample (L5) drawn after a 5 min flush of the outlet. At 45 sites with full lead service lines, 90th percentile lead levels in standing samples ranged from 16.4 to 44.5 μg L(-1) (L1 and L4, respectively). In the free-flowing sample (L5), 90th percentile lead was 9.8 μg L(-1). Within 3 days, full LSLR had reduced L3-L5 lead levels by more than 50%, and within 1 month, lead levels were significantly lower in every liter of the sample profile. Conversely, partial LSLR more than doubled premises plumbing (L1, L2) lead release in the short term and did not reduce L1, L2 lead release in the long term. Even 6 months after partial LSLR, 27% of first-draw lead levels were greater than 15 μg L(-1) (the U.S. EPA action level), compared with 13% pre-replacement.

  11. Modeling Soluble and Particulate Lead Release into Drinking Water from Full and Partially Replaced Lead Service Lines.

    PubMed

    Abokifa, Ahmed A; Biswas, Pratim

    2017-03-07

    Partial replacement of lead service lines (LSLs) often results in the excessive long-term release of lead particulates due to the disturbance of pipe scale and galvanic corrosion. In this study, a modeling approach to simulate the release and transport of particulate and dissolved lead from full and partially replaced LSLs is developed. A mass-transfer model is coupled with a stochastic residential water demand generator to investigate the effect of normal household usage flow patterns on lead exposure. The model is calibrated by comparing simulation results against experimental measurements from pilot-scale setups where lead release under different flow rates and water chemistry scenarios was reported. Applying the model within a Monte Carlo simulation framework, partial replacement of the LSL was predicted to result in releasing spikes with significantly high concentrations of particulate lead (1011.9 ± 290.3 μg/L) that were five times higher than those released from the simulated full LSL. Sensitivity analysis revealed that the intensity of flow demands significantly affects particulate lead release, while dissolved lead levels are more dependent on the lengths of the stagnation periods. Preflushing of the LSL prior to regulatory sampling was found to underestimate the maximum monthly exposure to dissolved lead by 19%, while sampling at low flow rates (<5.2 LPM) was found to consistently suppress the high spikes induced by particulate lead mobilization.

  12. Comparison of corrosion scales in full and partially replaced lead service lines after changes in water quality

    EPA Science Inventory

    Preliminary results from scales formed 38 weeks following the LSL replacement simulations revealed differences in scale formations amongst varying water qualities and pipe sequence. Rigs fed with dechlorinated tap water show distinct pH gradients between the galvanic and the back...

  13. Comparison of corrosion scales in full and partially replaced lead service lines after changes in water quality

    EPA Science Inventory

    Preliminary results from scales formed 38 weeks following the LSL replacement simulations revealed differences in scale formations amongst varying water qualities and pipe sequence. Rigs fed with dechlorinated tap water show distinct pH gradients between the galvanic and the back...

  14. Replacement of alloy 800H superheated steam line

    SciTech Connect

    Barbier, R.A.; Bullock, J.W.

    1996-07-01

    Sterling Chemicals utilizes alloy 800HT (UNS N08811) piping for superheated steam service in its styrene dehydrogenation unit. An engineering project to replace these lines was recently completed. Material acquisition, shop fabrication, inspection requirements, and field erection will be highlighted in this paper.

  15. NIF Laser Line Replaceable Units (LRUs)

    SciTech Connect

    Larson, D W

    2003-12-19

    The National Ignition Facility (NIF) is designed with its high value optical systems in cassettes called Line Replaceable Units (LRUs). Virtually all of the NIF's active components are assembled in one of the {approx}4000 electrical and optical LRUs that serve between two and eight of NIF's 192 laser beam lines. Many of these LRUs are optomechanical assemblies that are roughly the size of a telephone booth. The primary design challenges for this hardware include meeting stringent mechanical precision, stability and cleanliness requirements. Pre-production units of each LRU type have been fielded on the first bundle of NIF and used to demonstrate that NIF meets its performance objectives. This presentation provides an overview of the NIF LRUs, their design and production plans for building out the remaining NIF bundles.

  16. Forties oil line replacement overcomes sandwave challenge

    SciTech Connect

    Steel, W.J.M.; Imglis, R. )

    1991-03-06

    A major new 36-in., oil-export pipeline has been installed in the North Sea between the Forties field and Cruden Bay on the U.K. mainland. Designing and installing the line involved solving problems caused by sandwaves in the nearshore segment of the route. The Forties pipeline system covers offshore and land pipelines between the Forties field and the Firth of Forth tanker loading terminal and incorporates oil transportation, stabilization-gas separation, processing, and storage. The pipeline is used as part of an integrated oil and gas liquid gathering system from the central North Sea. Oil and gas liquids from other offshore fields are connected by subsea pipelines and riser to the Forties Charlie platform. Inspection of the existing 32-in. offshore pipeline had indicated signs of corrosion which would prevent the system from operating economically as future demands increased. In addition, when the line was commissioned in 1975, it was not envisioned that it would eventually carry crude from several other fields, which will come onstream this decade. The decision to lay a new 36-in. sealine reflects this need for increased capacity to ensure that the Forties pipeline system continues as a major carrier of oil and gas liquids well into the next century. Corrosion monitoring and inspection of the 32-in. line led to sections of the topside pipework being replaced in 1985 and the top section of the rise in 1987. The corrosion also resulted in the pipeline maximum allowable operating pressure (MAOP) being limited to 115 barg (1,668 psig) from 129 barg (1,871 psig).

  17. Orthopaedic service lines-revisited.

    PubMed

    Patterson, Cheryl

    2008-01-01

    This article revisits the application of orthopaedic service lines from early introduction and growth of this organizational approach in the 1980s, through the 1990s, and into the current decade. The author has experienced and worked in various service-line structures through these three decades, as well as the preservice-line era of 1970s orthopaedics. Past lessons learned during earlier phases and then current trends and analysis by industry experts are summarized briefly, with indication given of the future for service lines. Variation versus consistency of certain elements in service-line definitions and in operational models is discussed. Main components of service-line structures and typical processes are described briefly, along with a more detailed section on the service-line director/manager role. Current knowledge contained here will help guide the reader to more "out-of-the-box" thinking toward comprehensive orthopaedic centers of excellence.

  18. Does the joint line matter in revision total knee replacement?

    PubMed

    Porteous, A J; Hassaballa, M A; Newman, J H

    2008-07-01

    We identified 148 patients who had undergone a revision total knee replacement using a single implant system between 1990 and 2000. Of these 18 patients had died, six had developed a peri-prosthetic fracture and ten had incomplete records or radiographs. This left 114 with prospectively-collected radiographs and Bristol knee scores available for study. The height of the joint line before and after revision total knee replacement was measured and classified as either restored to within 5 mm of the pre-operative height or elevated if it was positioned more than 5 mm above the pre-operative height. The joint line was elevated in 41 knees (36%) and restored in 73 (64%). Revision surgery significantly improved the mean Bristol knee score from 41.1 (SD 15.9) pre-operatively to 80.5 (SD 15) post-operatively (p < 0.001). At one year post-operatively both the total Bristol knee score and its functional component were significantly better in the restored group than in the elevated group (p < 0.01). Overall, revision from a unicondylar knee replacement required less use of bone graft, fewer component augments, restored the joint line more often and gave a significantly better total Bristol knee score (p < 0.02) and functional score (p < 0.01) than revision from total knee replacement. Our findings show that restoration of the joint line at revision total knee replacement gives a significantly better result than leaving it unrestored by more than 5 mm. We recommend the greater use of distal femoral augments to help to achieve this goal.

  19. service line analytics in the new era.

    PubMed

    Spence, Jay; Seargeant, Dan

    2015-08-01

    To succeed under the value-based business model, hospitals and health systems require effective service line analytics that combine inpatient and outpatient data and that incorporate quality metrics for evaluating clinical operations. When developing a framework for collection, analysis, and dissemination of service line data, healthcare organizations should focus on five key aspects of effective service line analytics: Updated service line definitions. Ability to analyze and trend service line net patient revenues by payment source. Access to accurate service line cost information across multiple dimensions with drill-through capabilities. Ability to redesign key reports based on changing requirements. Clear assignment of accountability.

  20. Valuing Insect Pollination Services with Cost of Replacement

    PubMed Central

    Allsopp, Mike H.; de Lange, Willem J.; Veldtman, Ruan

    2008-01-01

    Value estimates of ecosystem goods and services are useful to justify the allocation of resources towards conservation, but inconclusive estimates risk unsustainable resource allocations. Here we present replacement costs as a more accurate value estimate of insect pollination as an ecosystem service, although this method could also be applied to other services. The importance of insect pollination to agriculture is unequivocal. However, whether this service is largely provided by wild pollinators (genuine ecosystem service) or managed pollinators (commercial service), and which of these requires immediate action amidst reports of pollinator decline, remains contested. If crop pollination is used to argue for biodiversity conservation, clear distinction should be made between values of managed- and wild pollination services. Current methods either under-estimate or over-estimate the pollination service value, and make use of criticised general insect and managed pollinator dependence factors. We apply the theoretical concept of ascribing a value to a service by calculating the cost to replace it, as a novel way of valuing wild and managed pollination services. Adjusted insect and managed pollinator dependence factors were used to estimate the cost of replacing insect- and managed pollination services for the Western Cape deciduous fruit industry of South Africa. Using pollen dusting and hand pollination as suitable replacements, we value pollination services significantly higher than current market prices for commercial pollination, although lower than traditional proportional estimates. The complexity associated with inclusive value estimation of pollination services required several defendable assumptions, but made estimates more inclusive than previous attempts. Consequently this study provides the basis for continued improvement in context specific pollination service value estimates. PMID:18781196

  1. Valuing insect pollination services with cost of replacement.

    PubMed

    Allsopp, Mike H; de Lange, Willem J; Veldtman, Ruan

    2008-09-10

    Value estimates of ecosystem goods and services are useful to justify the allocation of resources towards conservation, but inconclusive estimates risk unsustainable resource allocations. Here we present replacement costs as a more accurate value estimate of insect pollination as an ecosystem service, although this method could also be applied to other services. The importance of insect pollination to agriculture is unequivocal. However, whether this service is largely provided by wild pollinators (genuine ecosystem service) or managed pollinators (commercial service), and which of these requires immediate action amidst reports of pollinator decline, remains contested. If crop pollination is used to argue for biodiversity conservation, clear distinction should be made between values of managed- and wild pollination services. Current methods either under-estimate or over-estimate the pollination service value, and make use of criticised general insect and managed pollinator dependence factors. We apply the theoretical concept of ascribing a value to a service by calculating the cost to replace it, as a novel way of valuing wild and managed pollination services. Adjusted insect and managed pollinator dependence factors were used to estimate the cost of replacing insect- and managed pollination services for the Western Cape deciduous fruit industry of South Africa. Using pollen dusting and hand pollination as suitable replacements, we value pollination services significantly higher than current market prices for commercial pollination, although lower than traditional proportional estimates. The complexity associated with inclusive value estimation of pollination services required several defendable assumptions, but made estimates more inclusive than previous attempts. Consequently this study provides the basis for continued improvement in context specific pollination service value estimates.

  2. 25 CFR 169.22 - Service lines.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... power lines to a voltage of 14.5 kv. or less except lines to serve irrigation pumps and commercial and... 25 Indians 1 2014-04-01 2014-04-01 false Service lines. 169.22 Section 169.22 Indians BUREAU OF... Service lines. (a) An agreement shall be executed by and between the landowner or a legally authorized...

  3. 25 CFR 169.22 - Service lines.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... power lines to a voltage of 14.5 kv. or less except lines to serve irrigation pumps and commercial and... 25 Indians 1 2011-04-01 2011-04-01 false Service lines. 169.22 Section 169.22 Indians BUREAU OF... Service lines. (a) An agreement shall be executed by and between the landowner or a legally authorized...

  4. 25 CFR 169.22 - Service lines.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... power lines to a voltage of 14.5 kv. or less except lines to serve irrigation pumps and commercial and... 25 Indians 1 2010-04-01 2010-04-01 false Service lines. 169.22 Section 169.22 Indians BUREAU OF... Service lines. (a) An agreement shall be executed by and between the landowner or a legally authorized...

  5. 25 CFR 169.22 - Service lines.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... power lines to a voltage of 14.5 kv. or less except lines to serve irrigation pumps and commercial and... 25 Indians 1 2013-04-01 2013-04-01 false Service lines. 169.22 Section 169.22 Indians BUREAU OF... Service lines. (a) An agreement shall be executed by and between the landowner or a legally authorized...

  6. 25 CFR 169.22 - Service lines.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... power lines to a voltage of 14.5 kv. or less except lines to serve irrigation pumps and commercial and... 25 Indians 1 2012-04-01 2011-04-01 true Service lines. 169.22 Section 169.22 Indians BUREAU OF... Service lines. (a) An agreement shall be executed by and between the landowner or a legally authorized...

  7. Installation of line replaceable units into the National Ignition Facility

    SciTech Connect

    Bahowick, S; Mcmahon, D; Rowe, A; Tiszauer, D; Yakuma, S

    1999-03-08

    In the National Ignition Facility (NIF), currently under design and construction at Lawrence Livermore National Laboratory (LLNL), 192 high-power laser beamlines incorporating over 8,000 large optics, are focused onto a target smaller than a dime. The actual laser path will be contained within the Laser Target Area Building (LTAB), but the smaller adjacent building, the Optics Assembly Building, is where the optic modules are assembled and aligned. After the optics are finished in the OAB they must be transported and installed into the LTAB. While this is done strict cleanliness and handling conditions must be maintained. To maximize the efficiency of this process the optics are assembled into Line Replaceable Units (LRUs), which typically consist of a mechanical housing, laser optics, utilities, actuators and kinematic mounts. In this paper the Optical Transport and Material Handling designs that will be used to deliver the LRUs into the NIF laser bays are presented. Five types of delivery systems have been developed to deliver the LRUs to their locations in the LTAB. They are top loading, bottom loading, side loading, switchyard loading and target area loading. The first three operate in the laser bay of the LTAB and are transported between the OAB and the LTAB by the Laser Bay Transport System (LBTS). All delivery systems must maintain each optical LRU assemblies' specified shock, vibration, cleanliness, and environmental requirements. The design for each delivery system must take into consideration the cleanliness, functionality and alignment of the LRUs while maximizing commonality in order to meet the beamline installation schedule. This paper focuses on the design challenges of the bottom, side and top loading delivery systems and especially on how commonality among these varied systems is achieved.

  8. A LINE POLE 77A, HISTORIC POLE WITH HISTORIC REPLACEMENT PINTYPE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A LINE POLE 77A, HISTORIC POLE WITH HISTORIC REPLACEMENT PIN-TYPE INSULATORS MADE OF BROWN PORCELAIN. VIEW TO WEST-SOUTHWEST. - Mystic Lake Hydroelectric Facility, Electric Transmission A Line, Along West Rosebud Creek, Fishtail, Stillwater County, MT

  9. A LINE POLE 77A, DETAIL OF HISTORIC REPLACEMENT PINTYPE INSULATORS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A LINE POLE 77A, DETAIL OF HISTORIC REPLACEMENT PIN-TYPE INSULATORS MADE OF BROWN PORCELAIN. VIEW TO WEST-SOUTHWEST. - Mystic Lake Hydroelectric Facility, Electric Transmission A Line, Along West Rosebud Creek, Fishtail, Stillwater County, MT

  10. Selection Components in Background Replacement Lines of Drosophila

    PubMed Central

    Clark, Andrew G.; Bundgaard, Jørgen

    1984-01-01

    Selection components analysis was performed in lines of Drosophila melanogaster at three times during substitution backcrossing. The initial two lines were inbred isofemale lines from natural populations in California, and one had the spread wing mutation eagle. The selection components analysis revealed aspects of the genetic structure of the determinants of fitness by demonstrating changes in the marginal fitnesses of the eagle locus. Differences among backgrounds essentially disappeared by the 20th generation of backcrossing, suggesting that the previously observed differences were attributable to linkage disequilibrium. The method of bootstrapping was used as a novel means of determining statistical confidence in selection components. PMID:17246226

  11. Trans-Urals replacement NGL line nearing installation

    SciTech Connect

    Not Available

    1994-01-24

    Plans are advancing for construction of a Trans-Urals pipeline system to move NGLs from western Siberia to the Urals-Volga region. The system, currently envisioned as three 16-in. lines covering more than 1,000 miles, will move a mostly C[sub 3]-C[sub 5] stream from South Balyk (western Siberia) to petrochemical plants near Minnibaevo (Tatarstan) via Tchaikovsky. Supplies by pipelines have been interrupted since June 1989 when a massive leak from an existing 28-in. line caused an explosion that killed 765 people. Start up of construction was to have taken place later this year, but continuing Russian cash-flow problems to fund such major capital projects and declining NGL production in western Siberia have pushed back the project's timetable, say Western sources close to the project. The paper describes the export scheme which developers hope will improve cash flow, the pipeline and plant, and line size selection.

  12. IPAC datasets and on-line services.

    NASA Astrophysics Data System (ADS)

    Ebert, R.; Helou, G.; Mazzarella, J.; IPAC Tools Group

    The Infrared Processing and Analysis Center (IPAC) was created by NASA in 1983 to process and analyze data from the IRAS satellite. At present, IPAC on-line services are intended first to provide access to the extensive IRAS archives (catalogs, images, raw scan data) and second to support observation planning and data analysis for new IR missions, in particular ESA's Infrared Space Observatory (ISO). Here, information on access to the IPAC on-line catalogs is given and the software tools IRSKY, XCATSCAN, and XSCANPI are described in some detail.

  13. 49 CFR 192.365 - Service lines: Location of valves.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.365 Service lines: Location of valves. (a) Relation to regulator or meter..., upstream of the meter. (b) Outside valves. Each service line must have a shut-off valve in a...

  14. 49 CFR 192.365 - Service lines: Location of valves.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.365 Service lines: Location of valves. (a) Relation to regulator or meter..., upstream of the meter. (b) Outside valves. Each service line must have a shut-off valve in a...

  15. 49 CFR 192.365 - Service lines: Location of valves.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.365 Service lines: Location of valves. (a) Relation to regulator or meter..., upstream of the meter. (b) Outside valves. Each service line must have a shut-off valve in a...

  16. 49 CFR 192.365 - Service lines: Location of valves.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.365 Service lines: Location of valves. (a) Relation to regulator or meter..., upstream of the meter. (b) Outside valves. Each service line must have a shut-off valve in a...

  17. 49 CFR 192.365 - Service lines: Location of valves.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.365 Service lines: Location of valves. (a) Relation to regulator or meter..., upstream of the meter. (b) Outside valves. Each service line must have a shut-off valve in a...

  18. Planning, Building, and Maintaining a Successful Musculoskeletal Service Line.

    PubMed

    Sayeed, Zain; El-Othmani, Mouhanad M; Anoushiravani, Afshin A; Chambers, Monique C; Saleh, Khaled J

    2016-10-01

    Within the past 3 decades, a recent trend in the growth of musculoskeletal service lines has been seen nationally. Orthopedics offers an appealing concourse for implementation of service-line care. Within this review, the authors address the components involved in planning and building a musculoskeletal service line. The authors also address methods by which orthopedic surgeons can maintain the efficacy of their service lines by examining how orthopedic surgeons can navigate their service line through recent advents in health care reform. Finally, the authors review successful examples of musculoskeletal service lines currently in practice within the orthopedic community. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. 46 CFR 53.01-10 - Service restrictions and exceptions (replaces HG-101).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Service restrictions and exceptions (replaces HG-101). 53.01-10 Section 53.01-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING HEATING BOILERS General Requirements § 53.01-10 Service restrictions and exceptions (replaces HG...

  20. 40 CFR 141.84 - Lead service line replacement requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... taken pursuant to § 141.86(d)(2), after installing corrosion control and/or source water treatment... requirements. 141.84 Section 141.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84...

  1. 40 CFR 141.84 - Lead service line replacement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... taken pursuant to § 141.86(d)(2), after installing corrosion control and/or source water treatment... requirements. 141.84 Section 141.84 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.84...

  2. 49 CFR 192.375 - Service lines: Plastic.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Service lines: Plastic. 192.375 Section 192.375... § 192.375 Service lines: Plastic. (a) Each plastic service line outside a building must be installed... terminate above ground level and outside the building, if— (i) The above ground level part of the plastic...

  3. 49 CFR 192.375 - Service lines: Plastic.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Service lines: Plastic. 192.375 Section 192.375... § 192.375 Service lines: Plastic. (a) Each plastic service line outside a building must be installed... terminate above ground level and outside the building, if— (i) The above ground level part of the plastic...

  4. 49 CFR 192.375 - Service lines: Plastic.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Service lines: Plastic. 192.375 Section 192.375... § 192.375 Service lines: Plastic. (a) Each plastic service line outside a building must be installed... terminate above ground level and outside the building, if— (i) The above ground level part of the plastic...

  5. 49 CFR 192.375 - Service lines: Plastic.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Service lines: Plastic. 192.375 Section 192.375... § 192.375 Service lines: Plastic. (a) Each plastic service line outside a building must be installed... terminate above ground level and outside the building, if— (i) The above ground level part of the plastic...

  6. 49 CFR 192.375 - Service lines: Plastic.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Service lines: Plastic. 192.375 Section 192.375... § 192.375 Service lines: Plastic. (a) Each plastic service line outside a building must be installed... terminate above ground level and outside the building, if— (i) The above ground level part of the plastic...

  7. 49 CFR 192.371 - Service lines: Steel.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Service lines: Steel. 192.371 Section 192.371 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.371 Service lines: Steel. Each steel service line to be operated at less than 100 p.s.i. (689...

  8. 49 CFR 192.371 - Service lines: Steel.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Service lines: Steel. 192.371 Section 192.371 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.371 Service lines: Steel. Each steel service line to be operated at less than 100 p.s.i. (689...

  9. 49 CFR 192.371 - Service lines: Steel.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Service lines: Steel. 192.371 Section 192.371 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.371 Service lines: Steel. Each steel service line to be operated at less than 100 p.s.i. (689...

  10. 49 CFR 192.371 - Service lines: Steel.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Service lines: Steel. 192.371 Section 192.371 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.371 Service lines: Steel. Each steel service line to be operated at less than 100 p.s.i. (689...

  11. 49 CFR 192.371 - Service lines: Steel.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Service lines: Steel. 192.371 Section 192.371 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.371 Service lines: Steel. Each steel service line to be operated at less than 100 p.s.i. (689...

  12. 49 CFR 192.377 - Service lines: Copper.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Service lines: Copper. 192.377 Section 192.377 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.377 Service lines: Copper. Each copper service line installed within a building must be...

  13. 49 CFR 192.377 - Service lines: Copper.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Service lines: Copper. 192.377 Section 192.377 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.377 Service lines: Copper. Each copper service line installed within a building must be...

  14. 49 CFR 192.377 - Service lines: Copper.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Service lines: Copper. 192.377 Section 192.377 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.377 Service lines: Copper. Each copper service line installed within a building must be...

  15. 49 CFR 192.377 - Service lines: Copper.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Service lines: Copper. 192.377 Section 192.377 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.377 Service lines: Copper. Each copper service line installed within a building must be...

  16. 49 CFR 192.377 - Service lines: Copper.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Service lines: Copper. 192.377 Section 192.377 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... § 192.377 Service lines: Copper. Each copper service line installed within a building must be...

  17. 49 CFR 192.361 - Service lines: Installation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... buildings. Each underground service line installed below grade through the outer foundation wall of a... a plastic service line, be protected from shearing action and backfill settlement; and (3) Be sealed at the foundation wall to prevent leakage into the building. (f) Installation of service lines...

  18. Strategic service-line planning. Building competitive advantage.

    PubMed

    Greenspan, Elizabeth; Krentz, Susanna E; O'Neill, Molly K

    2003-12-01

    Service-line planning requires a healthcare organization to develop a business plan for each of its service lines. Successful service-line planning requires top leadership support, a willingness to allocate resources, the development of support mechanisms, the active support and involvement of physicians, and management commitment and accountability during implementation.

  19. 222-S radioactive liquid waste line replacement and 219-S secondary containment upgrade, Hanford Site, Richland, Washington

    SciTech Connect

    1995-01-01

    The U.S. Department of Energy (DOE) is proposing to: (1) replace the 222-S Laboratory (222-S) radioactive liquid waste drain lines to the 219-S Waste Handling Facility (219-S); (2) upgrade 219-S by replacing or upgrading the waste storage tanks and providing secondary containment and seismic restraints to the concrete cells which house the tanks; and (3) replace the transfer lines from 219-S to the 241-SY Tank Farm. This environmental assessment (EA) has been prepared in compliance with the National Environmental Policy Act (NEPA) of 1969, as amended, the Council on Environmental Quality Regulations for Implementing the Procedural Provisions of NEPA (40 Code of Federal Regulations [CFR] 1500-1508), and the DOE Implementing Procedures for NEPA (10 CFR 1021). 222-S is used to perform analytical services on radioactive samples in support of the Tank Waste Remediation System and Hanford Site environmental restoration programs. Activities conducted at 222-S include decontamination of analytical processing and support equipment and disposal of nonarchived radioactive samples. These activities generate low-level liquid mixed waste. The liquid mixed waste is drained through pipelines in the 222-S service tunnels and underground concrete encasements, to two of three tanks in 219-S, where it is accumulated. 219-S is a treatment, storage, and/or disposal (TSD) unit, and is therefore required to meet Washington Administrative Code (WAC) 173-303, Dangerous Waste Regulations, and the associated requirements for secondary containment and leak detection. The service tunnels are periodically inspected by workers and decontaminated as necessary to maintain as low as reasonably achievable (ALARA) radiation levels. Although no contamination is reaching the environment from the service tunnels, the risk of worker exposure is present and could increase. 222-S is expected to remain in use for at least the next 30 years to serve the Hanford Site environmental cleanup mission.

  20. 76 FR 76044 - Safety Zone; Power Line Replacement, West Bay, Panama City, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Power Line Replacement, West Bay, Panama... prohibited to all vessels and persons unless specifically authorized by the Captain of the Port (COTP) Mobile.... Coast Guard Sector Mobile (spw), Building 102, Brookley Complex South Broad Street Mobile, AL...

  1. Selecting physician leaders for clinical service lines: critical success factors.

    PubMed

    Epstein, Andrew L; Bard, Marc A

    2008-03-01

    Clinical service lines and interdisciplinary centers have emerged as important strategic programs within academic health centers (AHCs). Effective physician leadership is significant to their success, but how these leaders are chosen has not been well studied. The authors conducted a study to identify current models for selecting the physician leaders of clinical service lines, determine critical success factors, and learn how the search process affected service line performance. In 2003 and 2004, the authors interviewed clinical and executive personnel involved in 14 programs to establish, or consider establishing, heart or cancer service lines, at 13 AHCs. The responses were coded to identify and analyze trends and themes. The key findings of the survey were (1) the goals and expectations that AHCs set for their service line leaders vary greatly, depending on both the strategic purpose of the service line in the AHC and the service line's stage of development, (2) the matrix organizational structure employed by most AHCs limits the leader's authority over necessary resources, and calls forth a variety of compensating strategies if the service line is to succeed, (3) the AHCs studied used relatively informal processes to identify, evaluate, and select service line leaders, and (4) the leader's job is vitally shaped by the AHC's strategic, structural, and political context, and selection criteria should be determined accordingly. Institutions should be explicit about the strategic purpose and stage of development of their clinical service lines and be clear about their expectations and requirements in hiring service line leaders.

  2. 41 CFR 51-6.14 - Replacement services.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT PROCEDURES...-2 of this chapter. If another Government entity moves into the old location, the service at that...

  3. 41 CFR 51-6.14 - Replacement services.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT PROCEDURES...-2 of this chapter. If another Government entity moves into the old location, the service at that...

  4. 41 CFR 51-6.14 - Replacement services.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT PROCEDURES...-2 of this chapter. If another Government entity moves into the old location, the service at that...

  5. 41 CFR 51-6.14 - Replacement services.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT PROCEDURES...-2 of this chapter. If another Government entity moves into the old location, the service at that...

  6. 41 CFR 51-6.14 - Replacement services.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT PROCEDURES...-2 of this chapter. If another Government entity moves into the old location, the service at that...

  7. Metabolic syndrome: a new multidisciplinary service line.

    PubMed

    Frezza, Eldo E; Wachtel, Mitchell

    2011-03-01

    That obesity in the USA has reached epidemic proportions is undeniable: one in three American adults is obese. High levels of obesity yield adverse microeconomic and macroeconomic effects, but assessing the viability of bariatric surgery in this respect requires careful consideration of its efficacy, its economic costs, and the benefits of the surgery. Metabolic syndrome is a microcosm of multiple disease states; the diseases that fall under the umbrella of the metabolic syndrome are, like obesity, becoming more prevalent. Epidemic obesity in part reflects inadequate utilization of bariatric surgery and inadequate coordination of efforts by the healthcare system. An integrated delivery network (IDN) is the best current model to achieve healthcare goals for patient subsets that are deemed important. Our overweight population, both with and without the metabolic syndrome, constitutes such a group because of the fraction of the general population they compose, the inherent costs to the healthcare system that their comorbid conditions generate, and the lost productivity to our economy that the treatment of these conditions entail. In this paper, we show a metabolic syndrome service line that will benefit both the individual hospital and the healthcare system. Pathways accepted for bariatric practices can be used, with modification, for the creation of a metabolic syndrome IDN. Implementation of such a system would benefit patients, caregivers, and society.

  8. On-line replacement of program modules using AdaPT

    NASA Technical Reports Server (NTRS)

    Waldrop, Raymond S.; Volz, Richard A.; Smith, Gary W.; Holzbacher-Valero, A. A.; Goldsack, Stephen J.

    1992-01-01

    One purpose of our research is the investigation of the effectiveness and expressiveness of AdaPT(1), a set of language extensions to Ada 83, for distributed systems. As a part of that effort, we are now investigating the subject of replacing, e.g., upgrading, software modules while the software system remains in operation. The AdaPT language extension provide a good basis for this investigation for several reasons: (1) they include the concept of specific, self-contained program modules which can be manipulated; (2) support for program configuration is included in the language; and (3) although the discussion will be in terms of the AdaPT language, the AdaPT to Ada 83 conversion methodology being developed as another part of this project will provide a basis for the application of our findings to Ada 83 systems. The purpose of this investigation is to explore the basic mechanisms to the replacement process. Thus, while replacement in the presence of real-time deadlines, heterogeneous systems, and unreliable networks is certainly a topic of interest, we will first gain an understanding of the basic processes in the absence of such concerns. The extension of the replacement process to more complex situations can be made later. This report will establish an overview of the on-line upgrade problem, and present a taxonomy of the various aspects of the replacement process.

  9. 49 CFR 192.363 - Service lines: Valve requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... incorporated in a meter bar, that allows the meter to be bypassed, may not be used as a service-line valve....

  10. 49 CFR 192.363 - Service lines: Valve requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... incorporated in a meter bar, that allows the meter to be bypassed, may not be used as a service-line valve....

  11. 49 CFR 192.363 - Service lines: Valve requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... incorporated in a meter bar, that allows the meter to be bypassed, may not be used as a service-line valve....

  12. 49 CFR 192.363 - Service lines: Valve requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... incorporated in a meter bar, that allows the meter to be bypassed, may not be used as a service-line valve....

  13. 49 CFR 192.363 - Service lines: Valve requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... incorporated in a meter bar, that allows the meter to be bypassed, may not be used as a service-line valve....

  14. Building a Radiology Service Line: Key Elements and Necessary Actions.

    PubMed

    Hawkins, C Matthew

    2016-01-01

    Building a radiology service line is a challenge. Beyond the science of imaging and pathophysiology of disease, there are a number of key elements and necessary actions--related to personnel, communication, and resources--that must be taken to make the service line successful and sustainable. Although there is no single best way to build an imaging-based service line, there are a number of essential components. The purpose of this article is to delineate these components and describe how ambitious radiologists may successfully build and sustain a radiology service line. Copyright © 2015 Mosby, Inc. All rights reserved.

  15. 49 CFR 192.361 - Service lines: Installation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... backfill. Each service line must be properly supported on undisturbed or well-compacted soil, and material used for backfill must be free of materials that could damage the pipe or its coating. (c) Grading for... a plastic service line, be protected from shearing action and backfill settlement; and (3) Be...

  16. 49 CFR 192.361 - Service lines: Installation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... backfill. Each service line must be properly supported on undisturbed or well-compacted soil, and material used for backfill must be free of materials that could damage the pipe or its coating. (c) Grading for... a plastic service line, be protected from shearing action and backfill settlement; and (3) Be...

  17. 49 CFR 192.361 - Service lines: Installation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... backfill. Each service line must be properly supported on undisturbed or well-compacted soil, and material used for backfill must be free of materials that could damage the pipe or its coating. (c) Grading for... a plastic service line, be protected from shearing action and backfill settlement; and (3) Be...

  18. Measuring service line competitive position. A systematic methodology for hospitals.

    PubMed

    Studnicki, J

    1991-01-01

    To mount a broad effort aimed at improving their competitive position for some service or group of services, hospitals have begun to pursue product line management techniques. A few hospitals have even reorganized completely under the product line framework. The benefits include focusing accountability for operations and results, facilitating coordination between departments and functions, stimulating market segmentation, and promoting rigorous examination of new and existing programs. As part of its strategic planning process, a suburban Baltimore hospital developed a product line management methodology with six basic steps: (1) define the service lines (which they did by grouping all existing diagnosis-related groups into 35 service lines), (2) determine the contribution of each service line to total inpatient volume, (3) determine trends in service line volumes (by comparing data over time), (4) derive a useful comparison group (competing hospitals or groups of hospitals with comparable size, scope of services, payer mix, and financial status), (5) review multiple time frames, and (6) summarize the long- and short-term performance of the hospital's service lines to focus further analysis. This type of systematic and disciplined analysis can become part of a permanent strategic intelligence program. When hospitals have such a program in place, their market research, planning, budgeting, and operations will be tied together in a true management decision support system.

  19. 49 CFR 192.361 - Service lines: Installation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... millimeters) of cover in streets and roads. However, where an underground structure prevents installation at... buildings. Each underground service line installed below grade through the outer foundation wall of a... at the foundation wall to prevent leakage into the building. (f) Installation of service lines...

  20. Folsom-Nimbus 115 kV transmission line replacement for Western Area Power Administration: Environmental assessment

    SciTech Connect

    Not Available

    1980-07-01

    The Western Area Power Administration (Western) proposes to replace the existing Folsom-Nimbus 115 kV electrical transmission line along the American River between Folsom Dam and Nimbus Dam in Sacramento County, California. The need to replace the line is attributed to the deterioration of the existing wood pole structures by the acorn woodpecker; thus resulting in increased maintenance and hazard potential. The need for the replacement of the Folsom-Nimbus transmission line has resulted in the evaluation by Western of various routing alternatives. These alternatives were evaluated in terms of design, economic and environmental considerations. 60 refs., 19 figs., 4 tabs.

  1. Service life evaluation of rigid explosive transfer lines

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Kayser, E. G.; Schimmel, M. L.

    1983-01-01

    This paper describes a joint Army/NASA-sponsored research program on the service life evaluation of rigid explosive transfer lines. These transfer lines are used to initiate emergency crew escape functions on a wide variety of military and NASA aircraft. The purpose of this program was to determine quantitatively the effects of service, age, and degradation on rigid explosive transfer lines to allow responsible, conservative, service life determination. More than 800 transfer lines were removed from the U.S. Army AH-1G and AH-1S, the U.S. Air Force B-1 and F-111, and the U.S. Navy F-14 aircraft for testing. The results indicated that the lines were not adversely affected by age, service, or a repeat of the thermal qualification tests on full-service lines. Extension of the service life of rigid explosive transfer lines should be considered, since considerable cost savings could be realized with no measurable decrease in system reliability.

  2. Fundamentals of service lines and the necessity of physician leaders.

    PubMed

    Jain, Anshu K; Thompson, Jon M; Kelley, Scott M; Schwartz, Richard W

    2006-06-01

    In the demanding and unpredictable environment of the health care industry, hospitals and health systems continue to search for ways to improve the efficiency and quality of care provision and, thus, thrive. Service line organization in health care, a concept that was popularized in the past, has recently experienced a resurgence, spanning the gamut from small community hospitals to large academic medical centers. The modern service line has transformed into an organizational tool that provides hospitals and health systems with a novel approach to achieve the goals of efficient and effective care. Physician leaders can play an integral role in the management of service lines, using a combination of management skills and clinical expertise to provide the oversight and direction necessary for assuring excellence in clinical care and value in its delivery. This article presents an overview of service line structure, implementation, implications, and the role of the physician-leader.

  3. Integrating a clinical service line for maternal-child health.

    PubMed

    Stichler, J F; Branciforte, L

    1998-01-01

    Clinical integration is a developmental process that calls on the combined resources, expertise, and knowledge of individuals who may be working together for the first time. The process is dependent on the acknowledgment of the value of integration and a shared vision for the service line. By using a strategic thinking and planning process, the service line can be reshaped to function as an integrated system of programs and services that is sensitive to needs at a local level. While the task of integration is not an easy one, the outcomes of the process lead to a synergy that cannot be realized in any other manner.

  4. Finding of No Significant Impact: Replacement of Chemical Cleaning Line Tinker Air Force Base Oklahoma City, Oklahoma

    DTIC Science & Technology

    2012-05-01

    larger engine parts and future workload. Replacement of the existing cleaning line would provide a more energy-efficient operation that would reduce...water and chemical use, generate cost savings for overall cleaning line system operations, and accommodate larger engine parts. The EA has been... engine parts. Implementation of this action would provide an aircraft engine cleaning line capable of accommodating current and programmed workload in a

  5. Design and development of a 3He replacement safeguards neutron counter based on 10B-lined proportional detector technology

    SciTech Connect

    Henzlova, Daniela; Evans, Louise; Menlove, Howard O.; Swinhoe, Martyn T.; Rael, Carlos D.; Martinez, Isaac P.; Marlow, Johnna B.

    2012-07-16

    This presentation represents an overview of the experimental evaluation of a boron-lined proportional technology performed within an NA-241 sponsored project on testing of boron-lined proportional counters for the purpose of replacement of {sup 3}He technologies. The presented boron-lined technology will be utilized in a design of a full scale safeguards neutron coincidence counter. The design considerations and the Monte Carlo performance predictions for the counter are also presented.

  6. The Medium Tactical Vehicle Replacement Program-An Analysis of a Multi-Service Army and Marine Corps Product Office

    DTIC Science & Technology

    2004-06-01

    TACTICAL VEHICLE REPLACEMENT PROGRAM-AN ANALYSIS OF A MULTI-SERVICE ARMY AND MARINE CORPS PRODUCT OFFICE by Kenneth Edward Schramm June 2004...SUBTITLE: The Medium Tactical Vehicle Replacement Program-An Analysis of a Multi-Service Army and Marine Corps Product Office 6. AUTHOR(S) Kenneth...DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) The Marine Corps is fielding the MTVR Truck as a replacement for its aging fleet of five-ton

  7. Millennials, Technology and Perceived Relevance of Community Service Organizations: Is Social Media Replacing Community Service Activities?

    ERIC Educational Resources Information Center

    Hoffman, August John

    2017-01-01

    This mixed-methods qualitative study examined the relationship between perceptions of the importance of social media (i.e., Facebook, Twitter) with community service projects and volunteerism. Participants (n = 80) were interviewed and surveyed regarding their experiences in participating in a variety of community service work (CSW) projects…

  8. Millennials, Technology and Perceived Relevance of Community Service Organizations: Is Social Media Replacing Community Service Activities?

    ERIC Educational Resources Information Center

    Hoffman, August John

    2017-01-01

    This mixed-methods qualitative study examined the relationship between perceptions of the importance of social media (i.e., Facebook, Twitter) with community service projects and volunteerism. Participants (n = 80) were interviewed and surveyed regarding their experiences in participating in a variety of community service work (CSW) projects…

  9. 49 CFR 192.373 - Service lines: Cast iron and ductile iron.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Service lines: Cast iron and ductile iron. 192.373... Regulators, and Service Lines § 192.373 Service lines: Cast iron and ductile iron. (a) Cast or ductile iron... cast iron pipe or ductile iron pipe is installed for use as a service line, the part of the service...

  10. 49 CFR 192.373 - Service lines: Cast iron and ductile iron.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Service lines: Cast iron and ductile iron. 192.373... Regulators, and Service Lines § 192.373 Service lines: Cast iron and ductile iron. (a) Cast or ductile iron... cast iron pipe or ductile iron pipe is installed for use as a service line, the part of the service...

  11. 49 CFR 192.373 - Service lines: Cast iron and ductile iron.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Service lines: Cast iron and ductile iron. 192.373... Regulators, and Service Lines § 192.373 Service lines: Cast iron and ductile iron. (a) Cast or ductile iron... cast iron pipe or ductile iron pipe is installed for use as a service line, the part of the service...

  12. 49 CFR 192.373 - Service lines: Cast iron and ductile iron.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Service lines: Cast iron and ductile iron. 192.373... Regulators, and Service Lines § 192.373 Service lines: Cast iron and ductile iron. (a) Cast or ductile iron... cast iron pipe or ductile iron pipe is installed for use as a service line, the part of the service...

  13. 49 CFR 192.373 - Service lines: Cast iron and ductile iron.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Service lines: Cast iron and ductile iron. 192.373... Regulators, and Service Lines § 192.373 Service lines: Cast iron and ductile iron. (a) Cast or ductile iron... cast iron pipe or ductile iron pipe is installed for use as a service line, the part of the service...

  14. The on-line promotion and sale of nutrigenomic services.

    PubMed

    Sterling, Rene

    2008-11-01

    Nutrigenomic researchers hope to improve health through personalized nutrition, but many consider the sale of nutrigenomic services to be premature. Few studies have evaluated the promotion and sales practices of organizations hosting nutrigenomic websites. Systematic search and analysis of websites promoting nutrigenomic services in October 2006. Of the 64 organizations hosting websites, 29 organizations offered (24 of 29) or promoted (5 of 29) at-home testing and 26 organizations sold services on-line (17 of 26) or provided a direct link to on-line sales (9 of 26). A lack of transparency made it difficult to identify unique tests; however, three organizations were linked to 56% of all test mentions. Most organizations were healthcare/wellness service providers (50%) or laboratories/biotech companies (27%). Few organizations provided on-line information about laboratory certifications (20%), nutrigenomic test or research limitations (13%), test validity or utility (11%), or genetic counseling (9%). Affiliation opportunities were offered by 15 organizations. Organizations did not provide adequate information about nutrigenomic services and at-home genetic testing. Affiliation opportunities and distribution agreements suggest the promotion and sale of nutrigenomic services will continue, increasing the importance of consumer and provider education. In absence of federal regulation, organizations promoting nutrigenomic services should equate websites to product labels and include information to facilitate informed decision-making.

  15. Spectral Line-Shape Model to Replace the Voigt Profile in Spectroscopic Databases

    NASA Astrophysics Data System (ADS)

    Lisak, Daniel; Ngo, Ngoc Hoa; Tran, Ha; Hartmann, Jean-Michel

    2014-06-01

    The standard description of molecular line shapes in spectral databases and radiative transfer codes is based on the Voigt profile. It is well known that its simplified assumptions of absorber free motion and independence of collisional parameters from absorber velocity lead to systematic errors in analysis of experimental spectra, and retrieval of gas concentration. We demonstrate1,2 that the partially correlated quadratic speed-dependent hardcollision profile3. (pCqSDHCP) is a good candidate to replace the Voigt profile in the next generations of spectroscopic databases. This profile takes into account the following physical effects: the Doppler broadening, the pressure broadening and shifting of the line, the velocity-changing collisions, the speed-dependence of pressure broadening and shifting, and correlations between velocity- and phase/state-changing collisions. The speed-dependence of pressure broadening and shifting is incorporated into the pCqSDNGP in the so-called quadratic approximation. The velocity-changing collisions lead to the Dicke narrowing effect; however in many cases correlations between velocityand phase/state-changing collisions may lead to effective reduction of observed Dicke narrowing. The hard-collision model of velocity-changing collisions is also known as the Nelkin-Ghatak model or Rautian model. Applicability of the pCqSDHCP for different molecular systems was tested on calculated and experimental spectra of such molecules as H2, O2, CO2, H2O in a wide span of pressures. For all considered systems, pCqSDHCP is able to describe molecular spectra at least an order of magnitude better than the Voigt profile with all fitted parameters being linear with pressure. In the most cases pCqSDHCP can reproduce the reference spectra down to 0.2% or better, which fulfills the requirements of the most demanding remote-sensing applications. An important advantage of pCqSDHCP is that a fast algorithm for its computation was developedab4,5 and allows

  16. Evaluation of Hose in Hose transfer line service life

    SciTech Connect

    EAGLE, O.H.

    2003-05-30

    This document presents a determination for the amount of expected service life from Hose-in-Hose Transfer Lines based on vendor information and past HIHTL experience. Based on the information presented in this report and referenced documentation, we conclude the service life of the inner hose establishes the limits of service life for the finished assemblies. Since the process and environmental conditions to which the transfer line is subjected will not adversely affect the hose, the effective service life is that stated by the vendor--three years from the date of initial transfer. Transfer line assemblies have a shelf life of seven years from the date of hose manufacture, if stored in accordance with Section 2.1. This evaluation provides documentation showing that a three year service life has been justified. In the event that transfer lines are to be operated after three years from the date of initial transfer and within the shelf life of seven years, they must be reevaluated for their ability to perform intended functions.

  17. The re-emergence of clinical service line management.

    PubMed

    Litch, Bonnie K

    2007-01-01

    As healthcare leaders are positioning their organizations for a more competitive environment characterized by expanding consumer choice models, they are renewing their attention on organizing along clinical service lines. Bringing together clinical services in ways meaningful to patients can improve quality b better integrating care, while at the same time strengthening an organization's market position and creating new opportunities for increased physician collaboration--from collaborative planning to management to economic participation.

  18. Strengths of the Northwell Health Laboratory Service Line

    PubMed Central

    Balfour, Erika; Stallone, Robert; Castagnaro, Joseph; Poczter, Hannah; Schron, Deborah; Martone, James; Breining, Dwayne; Simpkins, Henry; Neglia, Tom; Kalish, Paul

    2016-01-01

    From 2009 to 2015, the laboratories of the 19-hospital North Shore-LIJ Health System experienced 5 threatened interruptions in service and supported 2 regional health-care providers with threatened interruptions in their laboratory service. We report our strategies to maintain laboratory performance during these events, drawing upon the strengths of our integrated laboratory service line. Established in 2009, the laboratory service line has unified medical and administrative leadership and system-wide divisional structure, quality management, and standardization of operations and procedures. Among many benefits, this governance structure enabled the laboratories to respond to a series of unexpected events. Specifically, at our various service sites, the laboratories dealt with pandemic (2009), 2 floods (2010, 2012), 2 fires (2010, 2015), and laboratory floor subsidence (2013). We were also asked to provide support for a regional physician network facing abrupt loss of testing services from closure of another regional clinical laboratory (2010) and to intervene for a non-health system hospital threatened with closure owing to noncompliance of laboratory operations (2012). In all but a single instance, patient care was served without interruption in service. In the last instance, fire interrupted laboratory services for 30 minutes. We conclude that in a large integrated health system, threats to continuous laboratory operations are not infrequent when measured on an annual basis. While most threats are from external physical circumstances, some emanate from unexpected administrative events. A strong laboratory governance mechanism that includes unified medical and administrative leadership across the entirety of the laboratory service line enables successful responses to these threats. PMID:28725768

  19. Resilient organizations: matrix model and service line management.

    PubMed

    Westphal, Judith A

    2005-09-01

    Resilient organizations modify structures to meet the demands of the marketplace. The author describes a structure that enables multihospital organizations to innovate and rapidly adapt to changes. Service line management within a matrix model is an evolving organizational structure for complex systems in which nurses are pivotal members.

  20. On-Line Services in Medicine and Beyond

    ERIC Educational Resources Information Center

    McCarn, Davis B.; Leiter, Joseph

    1973-01-01

    Discusses the development and operation of MEDLINE which was initiated by the National Library of Medicine in 1971. This is the first generally accessible, on-line, national and international information retrieval service, and allows almost instantaneous searching of over 400,000 citations from the world's biomedical serial literature. (JR)

  1. 49 CFR 192.511 - Test requirements for service lines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Test requirements for service lines. 192.511 Section 192.511 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Test Requirements § 192.511...

  2. 49 CFR 192.511 - Test requirements for service lines.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Test requirements for service lines. 192.511 Section 192.511 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND... TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Test Requirements § 192.511...

  3. Results after Cementless Medial Oxford Unicompartmental Knee Replacement - Incidence of Radiolucent Lines

    PubMed Central

    Panzram, Benjamin; Bertlich, Ines; Reiner, Tobias; Walker, Tilman; Hagmann, Sébastien; Weber, Marc-André; Gotterbarm, Tobias

    2017-01-01

    Purpose Tibial radiolucent lines (RL) are commonly seen in cemented unicompartmental knee replacement (UKR). In the postoperative course, they can be misinterpreted as signs of loosening, thus leading to unnecessary revision. Since 2004, a cementless OUKR is available. First studies and registry data have shown equally good clinical results of cementless OUKR compared to the cemented version and a significantly reduced incidence of RL in cementless implants. Methods This single-centre retrospective cohort study includes the first 30 UKR (27 patients) implanted between 2007 and 2009 with a mean follow-up of 5 years. Clinical outcome was evaluated using the OKS, AKS, range of movement (ROM) and level of pain (VAS). Standard radiologic evaluation was performed at three months, one and five years after surgery. The results five years after implantation were compared to a group of 27 cemented Oxford UKR (OUKR) in a matched-pair-analysis. Results Tibial RL were seen in 10 implants three months after operation, which significantly decreased to five after one year and to three after five years (p = 0.02). RL did not have a significant influence on revision (p = 1.0) or clinical outcome after five years. RL were always partial, never progressive and strictly limited to the tibia. There was no significant difference in the incidence of tibial RL five years after implantation between cemented and cementless implants (cemented: 4, cementless: 3, p = 1.0). Conclusions After cementless implantation RL were limited to the tibia, partial and never progressive. During short term follow-up the incidence of RL decreased significantly. RL seem to have no influence on clinical outcome and revision. PMID:28103308

  4. On-line PWR RHR pump performance testing following motor and impeller replacement

    SciTech Connect

    DiMarzo, J.T.

    1996-12-01

    On-line maintenance and replacement of safety-related pumps requires the performance of an inservice test to determine and confirm the operational readiness of the pumps. In 1995, major maintenance was performed on two Pressurized Water Reactor (PWR) Residual Heat Removal (RHR) Pumps. A refurbished spare motor was overhauled with a new mechanical seal, new motor bearings and equipped with pump`s `B` impeller. The spare was installed into the `B` train. The motor had never been run in the system before. A pump performance test was developed to verify it`s operational readiness and determine the in-situ pump performance curve. Since the unit was operating, emphasis was placed on conducting a highly accurate pump performance test that would ensure that it satisfied the NSSS vendors accident analysis minimum acceptance curve. The design of the RHR System allowed testing of one train while the other was aligned for normal operation. A test flow path was established from the Refueling Water Storage Tank (RWST) through the pump (under test) and back to the RWST. This allowed staff to conduct a full flow range pump performance test. Each train was analyzed and an expression developed that included an error vector term for the TDH (ft), pressure (psig), and flow rate (gpm) using the variance error vector methodology. This method allowed the engineers to select a test instrumentation system that would yield accurate readings and minimal measurement errors, for data taken in the measurement of TDH (P,Q) versus Pump Flow Rate (Q). Test results for the `B` Train showed performance well in excess of the minimum required. The motor that was originally in the `B` train was similarly overhauled and equipped with `A` pump`s original impeller, re-installed in the `A` train, and tested. Analysis of the `A` train results indicate that the RHR pump`s performance was also well in excess of the vendors requirements.

  5. Functional design criteria radioactive liquid waste line replacement, Project W-087. Revision 3

    SciTech Connect

    McVey, C.B.

    1994-10-13

    This document provides the functional design criteria for the 222-S Laboratory radioactive waste drain piping and transfer pipeline replacement. The project will replace the radioactive waste drain piping from the hot cells in 222-S to the 219-S Waste Handling Facility and provide a new waste transfer route from 219-S to the 244-S Catch Station in Tank Farms.

  6. In the Jungle of Astronomical On--line Data Services

    NASA Astrophysics Data System (ADS)

    Egret, D.

    The author tried to survive in the jungle of astronomical on--line data services. In order to find efficient answers to common scientific data retrieval requests, he had to collect many pieces of information, in order to formulate typical user scenarios, and try them against a number of different data bases, catalogue services, or information systems. He discovered soon how frustrating treasure coffers may be when their keys are not available, but he realized also that nice widgets and gadgets are of no help when the information is not there. And, before long, he knew he would have to navigate through several systems because no one was yet offering a general answer to all his questions. I will present examples of common user scenarios and show how they were tested against a number of services. I will propose some elements of classification which should help the end-user to evaluate how adequate the different services may be for providing satisfying answers to specific queries. For that, many aspects of the user interaction will be considered: documentation, access, query formulation, functionalities, qualification of the data, overall efficiency, etc. I will also suggest possible improvements to the present situation: the first of them being to encourage system managers to increase collaboration between one another, for the benefit of the whole astronomical community. The subjective review I will present, is based on publicly available astronomical on--line services from the U.S. and from Europe, most of which (excepting the newcomers) were described in ``Databases and On-Line Data in Astronomy", (Albrecht & Egret, eds, 1991): this includes databases (such as NED and Simbad ), catalog services ( StarCat , DIRA , XCatScan , etc.), and information systems ( ADS and ESIS ).

  7. Staff planning for operating rooms with different surgical services lines.

    PubMed

    Villarreal, Monica C; Keskinocak, Pinar

    2016-06-01

    We present a two-phase model for a staff planning problem in a surgical department. We consider the setting where staff, in particular nurse circulators and surgical scrub technicians, are assigned to one of different service lines, and while they can be 'pooled' and temporally assigned to other service line if needed, these re-assignments should belimited. In Phase I, we decide on the number of staff hours to budget for each service line, considering policies limiting staff pooling and overtime, and different demand scenarios. In Phase II, we determine how these budgeted staff hours should be allocated across potential work days and shifts, given estimated staff requirements and shift-related scheduling restrictions. We propose a heuristic to speed the model's Phase II solution time. We implement the model using a hospital's surgical data and compare the model's results with the hospital's current practices. Using a simulation model for the surgical operations, we find that our two-phase model reduces the delays caused by staff unavailability as well as staff pooling, without increasing the workforce size. Finally, we briefly describe a decision-support tool we developed with the objective of fine-tuning staff planning decisions.

  8. On-line Access to IPAC Datasets and Services

    NASA Astrophysics Data System (ADS)

    Ebert, R.

    In the past, IPAC has developed its tools and maintained its data archives to be maximally useful to visiting scientists working with IRAS data. With the IRAS data now approaching the 10 year anniversary, IPAC is making the transition to an on-line archive in order to support not only the continuing demand for access to IRAS catalogs and images, but in preparation for providing support for future infrared missions. IPAC's goal is to make all of its key data and services accessible via the Internet. Xcatscan is an on-line service providing access to the IPAC catalogs. IRSKY is a tool for planning observations in the infrared, as well as for browsing the on-line IRAS data products. It is being developed to support the astronomy community in preparing proposals for the European Infrared Space Observatory early next year. These two new services became available on the network last June. We will discuss the design strategy and implementation of these and other systems planned for the future.

  9. New Product Marketing Blurs the Line Between Nicotine Replacement Therapy and Smokeless Tobacco Products

    PubMed Central

    Kostygina, Ganna; England, Lucinda

    2016-01-01

    Tobacco companies have begun to acquire pharmaceutical subsidiaries and recently started to market nicotine replacement therapies, such as Zonnic nicotine gum, in convenience stores. Conversely, tobacco companies are producing tobacco products such as tobacco chewing gum and lozenges that resemble pharmaceutical nicotine replacement products, including a nicotine pouch product that resembles snus pouches. This convergence of nicotine and tobacco product marketing has implications for regulation and tobacco cessation. PMID:27077338

  10. New Product Marketing Blurs the Line Between Nicotine Replacement Therapy and Smokeless Tobacco Products.

    PubMed

    Kostygina, Ganna; England, Lucinda; Ling, Pamela

    2016-07-01

    Tobacco companies have begun to acquire pharmaceutical subsidiaries and recently started to market nicotine replacement therapies, such as Zonnic nicotine gum, in convenience stores. Conversely, tobacco companies are producing tobacco products such as tobacco chewing gum and lozenges that resemble pharmaceutical nicotine replacement products, including a nicotine pouch product that resembles snus pouches. This convergence of nicotine and tobacco product marketing has implications for regulation and tobacco cessation.

  11. Renal replacement therapy in support of Operation Iraqi Freedom: a tri-service perspective.

    PubMed

    Perkins, Robert; Simon, James; Jayakumar, Arun; Neff, Robert; Cohen, Irving; Bohen, Erin; Oliver, James; Kumke, Kevin; Older, Steven; Perkins, Jeremy; Grathwohl, Kurt; Yuan, Christina; Abbott, Kevin

    2008-11-01

    Experience with delivery of renal replacement therapy (RRT) in support of combat operations by the U.S. military has not been reported since the 1970s. We describe the tri-service military medical experience with RRT in support of Operation Iraqi Freedom. Through December 31, 2006, RRT was provided to 12 individuals inside the theater of operations. Navy medical personnel provided RRT to three patients (two U.S. active duty service members and one host nation individual) aboard the USNS Comfort, a mobile level 4 hospital. Dialysis was performed using conventional single-pass hemodialysis machines equipped with portable reverse osmosis systems. Army and Air Force medical personnel provided RRT to nine patients in theater (eight host nation patients and one U.S. active duty service member), using peritoneal dialysis and continuous renal replacement therapy (CRRT), not requiring trained renal nurses or technicians. Originally, U.S. military personnel with acute kidney injury (AKI) who were evacuated from theater to Landstuhl Regional Medical Center (LRMC), or those who developed AKI at LRMC were transferred to the German civilian medical system, if RRT was required. After creation of a rapid-response dialysis team and, later, positioning of a full-time active duty reserve nephrologist at LRMC, 16 patients received RRT at LRMC. None had required RRT in theater. Renal failure requiring RRT during combat operations remains an unusual but serious event, calling for flexibility in the provision of care. Notably, the Operation Iraqi Freedom experience has highlighted the needs of injured host nation patients with AKI and future military medical planning will need to account for their intratheater renal care.

  12. 47 CFR 69.130 - Line port costs in excess of basic analog service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Line port costs in excess of basic analog... basic analog service. To the extent that the costs of ISDN line ports, and line ports associated with other services, exceed the costs of a line port used for basic, analog service, non-price cap...

  13. 47 CFR 69.130 - Line port costs in excess of basic analog service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Line port costs in excess of basic analog... basic analog service. To the extent that the costs of ISDN line ports, and line ports associated with other services, exceed the costs of a line port used for basic, analog service, non-price cap...

  14. FEDIX on-line information service: Design, develop, test, and implement, an on-line research and education information service

    SciTech Connect

    Rodman, J.A.

    1992-01-01

    The FEDIX Annual Status Report provides details regarding an on-line information project designed, developed and implemented by Federal Information Exchange, Inc., a diversified information services company. This document details the project design activities, summarizes the developmental phases of the project and describes the implementation activities generated to fulfill the project's objectives. The information contained in this document illustrates FIE's continuing commitment to serve as the link that facilitates the dissemination of federal information to the education community. This report reviews the project accomplishments and describes intended service enhancements.

  15. 49 CFR 192.369 - Service lines: Connections to cast iron or ductile iron mains.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Service lines: Connections to cast iron or ductile iron mains. 192.369 Section 192.369 Transportation Other Regulations Relating to Transportation... Customer Meters, Service Regulators, and Service Lines § 192.369 Service lines: Connections to cast iron or...

  16. 49 CFR 192.369 - Service lines: Connections to cast iron or ductile iron mains.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Service lines: Connections to cast iron or ductile iron mains. 192.369 Section 192.369 Transportation Other Regulations Relating to Transportation... Customer Meters, Service Regulators, and Service Lines § 192.369 Service lines: Connections to cast iron or...

  17. 49 CFR 192.369 - Service lines: Connections to cast iron or ductile iron mains.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Service lines: Connections to cast iron or ductile iron mains. 192.369 Section 192.369 Transportation Other Regulations Relating to Transportation... Customer Meters, Service Regulators, and Service Lines § 192.369 Service lines: Connections to cast iron or...

  18. 49 CFR 192.369 - Service lines: Connections to cast iron or ductile iron mains.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Service lines: Connections to cast iron or ductile iron mains. 192.369 Section 192.369 Transportation Other Regulations Relating to Transportation... Customer Meters, Service Regulators, and Service Lines § 192.369 Service lines: Connections to cast iron or...

  19. 49 CFR 192.369 - Service lines: Connections to cast iron or ductile iron mains.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Service lines: Connections to cast iron or ductile iron mains. 192.369 Section 192.369 Transportation Other Regulations Relating to Transportation... Customer Meters, Service Regulators, and Service Lines § 192.369 Service lines: Connections to cast iron or...

  20. Replacement Technologies for Precision Cleaning of Aerospace Hardware for Propellant Service

    NASA Technical Reports Server (NTRS)

    Beeson, Harold; Kirsch, Mike; Hornung, Steven; Biesinger, Paul

    1997-01-01

    The NASA White Sands Test Facility (WSTF) is developing cleaning and verification processes to replace currently used chlorofluorocarbon-l13- (CFC-113-) based processes. The processes being evaluated include both aqueous- and solvent-based techniques. Replacement technologies are being investigated for aerospace hardware and for gauges and instrumentation. This paper includes the findings of investigations of aqueous cleaning and verification of aerospace hardware using known contaminants, such as hydraulic fluid and commonly used oils. The results correlate nonvolatile residue with CFC 113. The studies also include enhancements to aqueous sampling for organic and particulate contamination. Although aqueous alternatives have been identified for several processes, a need still exists for nonaqueous solvent cleaning, such as the cleaning and cleanliness verification of gauges used for oxygen service. The cleaning effectiveness of tetrachloroethylene (PCE), trichloroethylene (TCE), ethanol, hydrochlorofluorocarbon 225 (HCFC 225), HCFC 141b, HFE 7100(R), and Vertrel MCA(R) was evaluated using aerospace gauges and precision instruments and then compared to the cleaning effectiveness of CFC 113. Solvents considered for use in oxygen systems were also tested for oxygen compatibility using high-pressure oxygen autogenous ignition and liquid oxygen mechanical impact testing.

  1. Replacement Technologies for Precision Cleaning of Aerospace Hardware for Propellant Service

    NASA Technical Reports Server (NTRS)

    Beeson, Harold; Kirsch, Mike; Hornung, Steven; Biesinger, Paul

    1997-01-01

    The NASA White Sands Test Facility (WSTF) is developing cleaning and verification processes to replace currently used chlorofluorocarbon-l13- (CFC-113-) based processes. The processes being evaluated include both aqueous- and solvent-based techniques. Replacement technologies are being investigated for aerospace hardware and for gauges and instrumentation. This paper includes the findings of investigations of aqueous cleaning and verification of aerospace hardware using known contaminants, such as hydraulic fluid and commonly used oils. The results correlate nonvolatile residue with CFC 113. The studies also include enhancements to aqueous sampling for organic and particulate contamination. Although aqueous alternatives have been identified for several processes, a need still exists for nonaqueous solvent cleaning, such as the cleaning and cleanliness verification of gauges used for oxygen service. The cleaning effectiveness of tetrachloroethylene (PCE), trichloroethylene (TCE), ethanol, hydrochlorofluorocarbon 225 (HCFC 225), HCFC 141b, HFE 7100(R), and Vertrel MCA(R) was evaluated using aerospace gauges and precision instruments and then compared to the cleaning effectiveness of CFC 113. Solvents considered for use in oxygen systems were also tested for oxygen compatibility using high-pressure oxygen autogenous ignition and liquid oxygen mechanical impact testing.

  2. Development of a standard connector for orbital replacement units for serviceable spacecraft

    NASA Technical Reports Server (NTRS)

    Heath, Ellen F.; Braccio, Matthew A.; Raymus, Steven D.; Gross, David W.

    1987-01-01

    The current trend for spacecraft to be serviceable and repairable in orbit has led to a modular approach to satellite subsystem design. Spacecraft equipment, such as sensors, tape recorders, computers, transponders, batteries, etc., housed in discrete modular units, (Orbital Replacement Units(ORUs)) can be attached and detached to the spacecraft as needed. The interface between the ORU and the spacecraft is crucial. The projected use of robotics and the need for a common mechanism capable of performing several functions puts many constraints on the design of the interface. Such an interface mechanisms was designed and developed called the Standard Interface Connector (SIC) that mates the ORU to the spacecraft. The SIC also provides for the flow of fluids, data, and power between the module and spacecraft. The baseline design presented can be configured to provide various attachment schemes. Tests on SIC models have demonstrated the functionality of the design and its compatibility with current robotics.

  3. Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells.

    PubMed

    Inzunza, José; Gertow, Karin; Strömberg, Marie A; Matilainen, Eija; Blennow, Elisabeth; Skottman, Heli; Wolbank, Susanne; Ahrlund-Richter, Lars; Hovatta, Outi

    2005-04-01

    Derivation and culture of human embryonic stem cells (hESCs) without animal-derived material would be optimal for cell transplantation. We derived two new hES (HS293 and HS306) and 10 early cell lines using serum replacement (SR) medium instead of conventional fetal calf serum and human foreskin fibroblasts as feeder cells. Line HS293 has been in continuous culture, with a passage time of 5-8 days, since October 2003 and is at passage level 56. Line HS306 has been cultured since February 2004, now at passage 41. The lines express markers of pluripotent hESCs (Oct-4, SSEA-4, TRA-1-60, TRA-1-81, GCTM-2, and alkaline phosphatase). The pluripotency has been shown in embryoid bodies in vitro, and the pluripotency of line 293 has also been shown in vivo by teratoma formation in severe combined immunodeficiency/beige mice. The karyotype of HS293 is 46,XY, and that of HS306 is 46,XX. Ten more early lines have been derived under similar conditions since September 2004. We conclude that hESC lines can be successfully derived using SR medium and postnatal human fibroblasts as feeder cells. This is a step toward xeno-free conditions and facilitates the use of these cells in transplantation.

  4. Line drawing of Apollo 14 Command/Service Modules

    NASA Technical Reports Server (NTRS)

    1971-01-01

    a line drawing illustrating a cutaway view of the Apollo 14 Command/Service Modules, showing the engineering changes in the CSM which were recommended by the Apollo 13 Review Board. The major changes to the Apollo 14 CSM include adding a third cryogenic oxygen tank installed in an empty bay (in Sector one) of the Service Module (SM), addition of the auxiliary battery in the SM as a backup in case of fuel cell failure, and removal of destratification fans in the cryogenic oxygen tanks and removal of thermostat switches from the oxygen tank heater circuits. Provision for stowage of an emergency five gallon supply of drinking water has been added to the Command Module (CM).

  5. Rehabilitation services after total joint replacement in Ontario, Canada: can 'prehabilitation' programs mediate an increasing demand?

    PubMed

    Landry, Michel D; Jaglal, Susan B; Wodchis, Walter P; Cooper, Nicole S; Cott, Cheryl A

    2007-12-01

    Total joint replacements (TJR) have emerged as a critical health policy issue. In particular, Canadian demand for these surgeries is forecast to grow annually by 8.7% in the next decade. Although the medical and surgical aspects of TJR have received considerable attention, very little research has explored the impact of increased TJR on the demand for rehabilitation services. In this study, we conducted seven focus group discussions across the province of Ontario (Canada) with multiple stakeholders (n=50) ranging from clinicians and administrators, to policy makers and researchers. Our results indicate that demand for rehabilitation following TJR is rising sharply and that there are three primary factors affecting such demand: (i) increase in the absolute number of TJR surgeries is increasing demand across the continuum of care; (ii) changing profile of clients whereby 'younger and active' groups are more willing to undergo surgery, and 'older and complex' groups are presenting with increased rates of medical complications and comorbidities; and (iii) widespread use of clinical pathways has increased requirements within the rehabilitation sector, but often without corresponding adjustments in levels of human resources. To align increasing demand with supply in the long term, participants offered strong support for health promotion and prevention programs, but they also highlighted the short-term benefits of implementing 'prehabilitation' programs for clients waiting for surgery. Overall, our results indicate that the demand for rehabilitation services after TJR is increasing and that innovative approaches to care delivery are required to align increasing demand with supply.

  6. Service line assessment and performance management through information integration: the case for cardiovascular services.

    PubMed

    Salaway, T; Burris, C

    2001-11-01

    Understanding the performance of clinically sophisticated services has become increasingly vital to ensuring the success of a health care organization. Health care delivery systems and providers will require well-designed performance management systems, which is underscored by an operating environment of declining margins, increased capacity issues, and labor shortages in key areas. This article reviews the case for cardiovascular service line assessment and performance management, specifically as a case study example of strategic, focused, and actionable measurement and assessment of clinical and financial performance for both clinical and administrative leaders. The integration of administrative data for comprehensive and strategic assessment of clinically sophisticated services is explored in depth, along with product line definition and positioning.

  7. Description of the attitude control, guidance and navigation space replaceable units for automated space servicing of selected NASA missions

    NASA Technical Reports Server (NTRS)

    Chobotov, V. A.

    1974-01-01

    Control elements such as sensors, momentum exchange devices, and thrusters are described which can be used to define space replaceable units (SRU), in accordance with attitude control, guidance, and navigation performance requirements selected for NASA space serviceable mission spacecraft. A number of SRU's are developed, and their reliability block diagrams are presented. An SRU assignment is given in order to define a set of feasible space serviceable spacecraft for the missions of interest.

  8. Line drawing of Apollo 14 Command/Service Modules

    NASA Image and Video Library

    1971-01-12

    S71-16823 (January 1971) --- A line drawing illustrating a cutaway view of the Apollo 14 Command and Service Modules, showing the engineering changes in the CSM which were recommended by the Apollo 13 Review Board. (The Apollo 13 abort was caused by a short circuit and wiring overheating in one of the SM cryogenic oxygen tanks.) The major changes to the Apollo 14 CSM include adding a third cryogenic oxygen tank installed in a heretofore empty bay (in sector one) of the SM, addition of an auxiliary battery in the SM as a backup in case of fuel cell failure, and removal of destratification fans in the cryogenic oxygen tanks and removal of thermostat switches from the oxygen tank heater circuits. Provision for stowage of an emergency five-gallon supply of drinking water has been added to the CM.

  9. “Meniscal” scar as a landmark for the joint line in revision total knee replacement

    PubMed Central

    Khan, Wasim Sardar; Bhamra, Jagmeet; Williams, Rhodri; Morgan-Jones, Rhidian

    2017-01-01

    AIM To determine whether tissue identified at the joint line was actually remnant “meniscal” scar tissue or not. METHODS Nine patients undergoing revision knee surgery following informed consent had meniscal scar tissue sent to the histology department for analyses. All revisions were performed where joint line had been raised or lowered at earlier surgery. Although preoperative radiographic evaluations suggested that the joint line had been altered, intraoperatively there was scar tissue at the level of the recreated joint line. This scar tissue has traditionally been described as meniscal scar, and to identify the origins of this tissue, samples were sent for histological analyses. The tissue samples were stored in formalin, and embedded and sectioned before undergoing histochemical staining. All samples underwent macroscopic and microscopic examination by a histopathologist who was blind to the study aims. The specific features that were examined included tissue organisation, surface and central composition, cellular distribution including histiocytes, nuclear ratio and vasculature. Atypical and malignant features, inflammation and degeneration were specifically looked for. A statistical review of the study was performed by a biomedical statistician. RESULTS The histological findings for the nine patients showing the macroscopic and microscopic findings, and the conclusion are outlined in a Table. The histological analyses were reviewed to determine whether the tissue samples were likely to be meniscal scar tissue. The response was yes (2, 22%), no (6, 67%) and maybe (1, 11%) based on the conclusions. The results were “yes” when on macroscopy, firm cream tissue was identified. In these two “yes” samples, microscopic analyses showed organised fibrous tissue with focal degenerative areas with laminated pattern associated with histiocytes peripherally but no inflammation. The “no” samples were assessed macroscopically and microscopically and were

  10. How geostatistics can help you find lead and galvanized water service lines: The case of Flint, MI.

    PubMed

    Goovaerts, Pierre

    2017-12-01

    In the aftermath of Flint drinking water crisis, most US cities have been scrambling to locate all lead service lines (LSLs) in their water supply systems. This information, which is most often inaccurate or lacking, is critical to assess compliance with the Lead and Copper Rule and to plan the replacement of lead and galvanized service lines (GSLs) as currently under way in Flint. This paper presents the first geospatial approach to predict the likelihood that a home has a LSL or GSL based on neighboring field data (i.e., house inspection) and secondary information (i.e., construction year and city records). The methodology is applied to the City of Flint where 3254 homes have been inspected by the Michigan Department of Environmental Quality to identify service line material. GSLs and LSLs were mostly observed in houses built prior to 1934 and during World War II, respectively. City records led to the over-identification of LSLs, likely because old records were not updated as these lines were being replaced. Indicator semivariograms indicated that both types of service line are spatially clustered with a range of 1.4km for LSLs and 2.8km for GSLs. This spatial autocorrelation was integrated with secondary data using residual indicator kriging to predict the probability of finding each type of material at the tax parcel level. Cross-validation analysis using Receiver Operating Characteristic (ROC) Curves demonstrated the greater accuracy of the kriging model relative to the current approach targeting houses built in the forties; in particular as more field data become available. Anticipated rates of false positives and percentages of detection were computed for different sampling strategies. This approach is flexible enough to accommodate additional sources of information, such as local code and regulatory changes, historical permit records, maintenance and operation records, or customer self-reporting. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. 47 CFR 69.157 - Line port costs in excess of basic, analog service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Line port costs in excess of basic, analog... § 69.157 Line port costs in excess of basic, analog service. To the extent that the costs of ISDN line..., analog service, local exchange carriers may recover the difference through a separate monthly...

  12. 49 CFR 192.381 - Service lines: Excess flow valve performance standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Meters, Service Regulators, and Service Lines § 192.381 Service lines: Excess flow valve performance... hour (0.57 cubic meters per hour); or (B) For an excess flow valve designed to prevent equalization of pressure across the valve, to no more than 0.4 cubic feet per hour (.01 cubic meters per hour); and (4)...

  13. 49 CFR 192.381 - Service lines: Excess flow valve performance standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Meters, Service Regulators, and Service Lines § 192.381 Service lines: Excess flow valve performance... hour (0.57 cubic meters per hour); or (B) For an excess flow valve designed to prevent equalization of pressure across the valve, to no more than 0.4 cubic feet per hour (.01 cubic meters per hour); and (4)...

  14. 49 CFR 192.381 - Service lines: Excess flow valve performance standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Meters, Service Regulators, and Service Lines § 192.381 Service lines: Excess flow valve performance... hour (0.57 cubic meters per hour); or (B) For an excess flow valve designed to prevent equalization of pressure across the valve, to no more than 0.4 cubic feet per hour (.01 cubic meters per hour); and (4)...

  15. 49 CFR 192.381 - Service lines: Excess flow valve performance standards.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Meters, Service Regulators, and Service Lines § 192.381 Service lines: Excess flow valve performance... hour (0.57 cubic meters per hour); or (B) For an excess flow valve designed to prevent equalization of pressure across the valve, to no more than 0.4 cubic feet per hour (.01 cubic meters per hour); and (4)...

  16. 49 CFR 192.381 - Service lines: Excess flow valve performance standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Meters, Service Regulators, and Service Lines § 192.381 Service lines: Excess flow valve performance... hour (0.57 cubic meters per hour); or (B) For an excess flow valve designed to prevent equalization of pressure across the valve, to no more than 0.4 cubic feet per hour (.01 cubic meters per hour); and (4)...

  17. 49 CFR 192.367 - Service lines: General requirements for connections to main piping.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... connections to main piping. 192.367 Section 192.367 Transportation Other Regulations Relating to... STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.367 Service lines: General... main connection must: (1) Be designed and installed to effectively sustain the longitudinal pull-out or...

  18. 47 CFR 69.713 - Common line, traffic-sensitive, and tandem-switched transport services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.713 Common line... pricing flexibility with respect to the following services: (1) Common line services, as described in... described in §§ 69.111(a)(2)(i) and (ii). (b) Phase I triggers. (1) To obtain Phase I pricing...

  19. 47 CFR 69.713 - Common line, traffic-sensitive, and tandem-switched transport services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.713 Common line... pricing flexibility with respect to the following services: (1) Common line services, as described in... described in §§ 69.111(a)(2)(i) and (ii). (b) Phase I triggers. (1) To obtain Phase I pricing...

  20. 47 CFR 69.713 - Common line, traffic-sensitive, and tandem-switched transport services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.713 Common line... pricing flexibility with respect to the following services: (1) Common line services, as described in... described in §§ 69.111(a)(2)(i) and (ii). (b) Phase I triggers. (1) To obtain Phase I pricing...

  1. 47 CFR 69.713 - Common line, traffic-sensitive, and tandem-switched transport services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.713 Common line... pricing flexibility with respect to the following services: (1) Common line services, as described in... described in §§ 69.111(a)(2)(i) and (ii). (b) Phase I triggers. (1) To obtain Phase I pricing...

  2. 47 CFR 69.713 - Common line, traffic-sensitive, and tandem-switched transport services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Pricing Flexibility § 69.713 Common line... pricing flexibility with respect to the following services: (1) Common line services, as described in... described in §§ 69.111(a)(2)(i) and (ii). (b) Phase I triggers. (1) To obtain Phase I pricing...

  3. Quality Assurance Plan for site electrical replacements at substation line item subproject: 69 KV Substation

    SciTech Connect

    Ohler, C.K.

    1991-05-21

    The 69 KV Substation Project is based on the recognized need to provide a continuous, reliable source of power and to improve the firm capacity of the electrical service to all production facilities at Mound. The project consists of the following major element: 69 KV Substation: (1) Install a 69 KV Substation and associated equipment with two parallel 18 MVA transformers. (2) Install duct bank as required and provide 15 KV feeder cable from new substation to existing Substation 95 for connection to Mound`s existing primary distribution system. (3) Install duct bank for underground routing of the 15 KV feeder cable from Manhole 5C to the existing power house cable pit. (4) Reconfigure existing Dayton Power and Light Co. 15 KV switchgear in P Building. The purpose of this Quality Assurance Plan (QA Plan) is to assure that the objectives of the United States Department of Energy (D.O.E.) and EG&G Mound Applied Technologies, Miamisburg, Ohio (Mound) are met for this non-weapons project relative to health and safety, protection of the environment, reliability and continuity of operations, and documentation of quality efforts. This QA Plan identifies the activities and responsibilities which are necessary in the design, procurement, fabrication, installation, and start up of this project in order to meet these objectives.

  4. 77 FR 4821 - Public Health Service Act, Non-competitive Replacement Award

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... HUMAN SERVICES Health Resources and Services Administration Public Health Service Act, Non-competitive...: Section 330I(d)(2) of the Public Health Service Act, as amended, 42 U.S.C. 254c-14(d)(2). Catalog of... INFORMATION CONTACT: Monica Cowan, Public Health Analyst, Office for the Advancement of Telehealth, Office of...

  5. 49 CFR 192.379 - New service lines not in use.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... must be installed in the service line or in the meter assembly. (c) The customer's piping must...

  6. 49 CFR 192.379 - New service lines not in use.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... must be installed in the service line or in the meter assembly. (c) The customer's piping must...

  7. 49 CFR 192.379 - New service lines not in use.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... must be installed in the service line or in the meter assembly. (c) The customer's piping must...

  8. 49 CFR 192.379 - New service lines not in use.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... must be installed in the service line or in the meter assembly. (c) The customer's piping must...

  9. 49 CFR 192.379 - New service lines not in use.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators... must be installed in the service line or in the meter assembly. (c) The customer's piping must...

  10. Service and repair of the rammed lining of a rotary furnace

    SciTech Connect

    Startsev, D.A.; Khamatova, V.G.; Murzin, V.N.

    1986-03-01

    The rotary furnace is designed for heating of carbon and alloy steel billets 100-150 mm in diameter and 1000-3800 mm long with a maximum weight of 350 kg to 1130-1260 degrees C. The furnace hearth lining is made in three layers. The top of the center layer is made of parts laid with gaps between them of 20-30 mm. The 80-90-mm-thick working layer is made of type MKhGP-35 rammed chromite-clay compound. To protect the top of the side parts of the hearth from impacts, they are covered with a 40-mm-thick layer of rammed MKhGP-35 compound. During operation of the furnace and heating of the billets, the rammed compound of the hearth is compacted and after 6-7 months of service waves up to 20-30 mm deep are formed on it from the action of the round billets. To avoid the condition in which the unloading machine is not able to take the heated billets from such a hearth, ramming compound is added to the depressions in the hearth through the charging door. The furnace temperature is brought up to the heating schedule and billets are charged. The rammed lining is completely replaced once every two or three years. The saving with such a method of repair of the worn rammed hearth during 2 years of operation of the rotary furnace is substantial.

  11. Managing Variation in Services in a Software Product Line Context

    DTIC Science & Technology

    2010-05-01

    Oriented Domain Analysis ( FODA ) Feasibility Study (CMU/SEI-90-TR-021, ADA235785). Software Engineering Institute, Carnegie Mellon University, 1990...the systems in the product line, and a plan for building the systems. Product line scope and product line analysis define the boundaries and...systems, as well as expected ways in which they may vary. Product line analysis applies established modeling techniques to engineer the common and

  12. Extension of service life of rigid transfer lines /SMDC/. [explosive components for aircraft escape systems

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Kayser, E. G.; Schimmel, M. L.

    1982-01-01

    The results of a life evaluation program on rigid explosive transfer lines, which are used to initiate aircraft emergency crew escape functions, are presented in order to provide quantitative information on rigid explosive transfer lines which can contribute to responsible, conservative, service life determinations. The program involved the development of a test methodology, testing of the three types of transfer lines in use in the U.S., testing of these lines following a repeat of the thermal test conducted in the original qualification, and conducting a degradation investigation. Results from the testing of more than 800 components showed that rigid explosive transfer lines were not affected by age, service, or a repeat of the thermal qualification tests on full-service lines. The explosive degradation limits were approximated and the mechanisms examined. It is concluded that the service lives of rigid explosive transfer lines should be considered for extension in order to provide cost savings and increased system reliability.

  13. Extension of service life of rigid transfer lines /SMDC/. [explosive components for aircraft escape systems

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Kayser, E. G.; Schimmel, M. L.

    1982-01-01

    The results of a life evaluation program on rigid explosive transfer lines, which are used to initiate aircraft emergency crew escape functions, are presented in order to provide quantitative information on rigid explosive transfer lines which can contribute to responsible, conservative, service life determinations. The program involved the development of a test methodology, testing of the three types of transfer lines in use in the U.S., testing of these lines following a repeat of the thermal test conducted in the original qualification, and conducting a degradation investigation. Results from the testing of more than 800 components showed that rigid explosive transfer lines were not affected by age, service, or a repeat of the thermal qualification tests on full-service lines. The explosive degradation limits were approximated and the mechanisms examined. It is concluded that the service lives of rigid explosive transfer lines should be considered for extension in order to provide cost savings and increased system reliability.

  14. Trace Metal Associations with Manganese-Rich Surface Coatings of Lead Service Lines

    EPA Science Inventory

    Analysis of lead service line samples from U. S. Environmental Protection Agency’s long-term research program to evaluate control and metal release from domestic drinking water service lines has revealed that Manganese-rich solids also contain Iron and sometimes Aluminum have fre...

  15. Microbial Community Profile of a Lead Service Line Removed from a Drinking Water Distribution System▿

    PubMed Central

    White, Colin; Tancos, Matthew; Lytle, Darren A.

    2011-01-01

    A corroded lead service line was removed from a drinking water distribution system, and the microbial community was profiled using 16S rRNA gene techniques. This is the first report of the characterization of a biofilm on the surface of a corroded lead drinking water service line. The majority of phylotypes have been linked to heavy-metal-contaminated environments. PMID:21652741

  16. Microbial community profile of a lead service line removed from a drinking water distribution system.

    PubMed

    White, Colin; Tancos, Matthew; Lytle, Darren A

    2011-08-01

    A corroded lead service line was removed from a drinking water distribution system, and the microbial community was profiled using 16S rRNA gene techniques. This is the first report of the characterization of a biofilm on the surface of a corroded lead drinking water service line. The majority of phylotypes have been linked to heavy-metal-contaminated environments.

  17. Trace Metal Associations with Manganese-Rich Surface Coatings of Lead Service Lines

    EPA Science Inventory

    Analysis of lead service line samples from U. S. Environmental Protection Agency’s long-term research program to evaluate control and metal release from domestic drinking water service lines has revealed that Manganese-rich solids also contain Iron and sometimes Aluminum have fre...

  18. Ecological Psychology: Replacing the Medical Model Paradigm for School-Based Psychological and Psychoeducational Services

    ERIC Educational Resources Information Center

    Gutkin, Terry B.

    2012-01-01

    Traditional medical model service delivery systems have facilitated the creation of nationwide mental health and education pandemics for children and youth. The characteristics and shortcomings of medical model approaches leading to these problems are explicated, including the focus of services on individuals rather than populations, relying…

  19. Ecological Psychology: Replacing the Medical Model Paradigm for School-Based Psychological and Psychoeducational Services

    ERIC Educational Resources Information Center

    Gutkin, Terry B.

    2012-01-01

    Traditional medical model service delivery systems have facilitated the creation of nationwide mental health and education pandemics for children and youth. The characteristics and shortcomings of medical model approaches leading to these problems are explicated, including the focus of services on individuals rather than populations, relying…

  20. Replacing Mn2+ with Co2+ in Human Arginase I Enhances Cytotoxicity toward L-Arginine Auxotrophic Cancer Cell Lines

    SciTech Connect

    Stone, E.; Glazer, E; Chantranupong, L; Cherukuri, P; Breece, R; Tierney, D; Curley, S; Iverson, B; Georgiou, G

    2010-01-01

    Replacing the two Mn{sup 2+} ions normally present in human Arginase I with Co{sup 2+} resulted in a significantly lowered K{sub M} value without a concomitant reduction in k{sub cat}. In addition, the pH dependence of the reaction was shifted from a pK{sub a} of 8.5 to a pK{sub a} of 7.5. The combination of these effects led to a 10-fold increase in overall catalytic activity (k{sub cat}/K{sub M}) at pH 7.4, close to the pH of human serum. Just as important for therapeutic applications, Co{sup 2+} substitution lead to significantly increased serum stability of the enzyme. Our data can be explained by direct coordination of L-Arg to one of the Co{sup 2+} ions during reaction, consistent with previously reported model studies. In vitro cytotoxicity experiments verified that the Co{sup 2+}-substituted human Arg I displays an approximately 12- to 15-fold lower IC{sub 50} value for the killing of human hepatocellular carcinoma and melanoma cell lines and thus constitutes a promising new candidate for the treatment of L-Arg auxotrophic tumors.

  1. Replacing Mn2+ with Co2+ in Human Arginase I Enhances Cytotoxicity Towards L-Arginine Auxotrophic Cancer Cell Lines

    PubMed Central

    Stone, Everett M.; Glazer, Evan S.; Chantranupong, Lynne; Cherukuri, Paul; Breece, Robert M.; Tierney, David L.; Curley, Steven A.; Iverson, Brent L.; Georgiou, George

    2010-01-01

    Replacing the two Mn2+ ions normally present in human Arginase I with Co2+ resulted in a significantly lowered KM value without a concomitant reduction in kcat. In addition, the pH dependence of the reaction was shifted from a pKa of 8.5 to a pKa of 7.5. The combination of these effects lead to a 10-fold increase in overall catalytic activity (kcat/KM) at pH 7.4, close to the pH of human serum. Just as important for therapeutic applications, Co2+ substitution lead to significantly increased serum stability of the enzyme. Our data can be explained by direct coordination of l-Arg to one of the Co2+ ions during reaction, consistent with previously reported model studies. In vitro cytotoxicity experiments verified that the Co2+ substituted human Arg I displays an approximately 12-15-fold lower IC50 value for the killing of human hepatocellular carcinoma and melanoma cell lines, and thus constitutes a promising new candidate for the treatment of l-Arg auxotrophic tumors. PMID:20050660

  2. Using embedded systems for the remote delivery and recovery of National Ignition Facility and optical line replaceable units

    SciTech Connect

    Perez, M L

    1999-01-19

    This paper describes the design and development of the embedded control systems used to deliver and recover the National Ignition Facility (NIF) optical line replaceable units (LRUs). As part of the NIF Operations Special Equipment Control System (OSECS), the embedded control systems form a part of the front end processor (FEP) layer of the OSECS. During the start-up and operations phases of the NIF project, it is anticipated that a significant number of LRUs will be delivered to the laser beamline structure. The frequency of LRU delivery combined with the design of the facility pose severe constraints for human-only delivery and recovery operations. To reduce the risks to personnel and to allow for safe and efficient delivery of equipment, LLNL engineers are designing and developing embedded control systems for the low-level device control of NIF Transport and Handling mechanical delivery system components. The design of the embedded control system makes use of advanced PC-based motion control technology commonly found in industrial applications. The PC-based platform consists of commercial-off-the-shelf (COTS) hardware and software such as industrial computers, motion controllers, data acquisition boards, sensors technology, networking capabilities, development languages and operating system. Wireless networking technology is also being employed in the design to achieve a distributed control architecture for operator mobility during operations. Additionally, the PC-based platform provides the greatest degree of flexibility in satisfying a diverse set of motion control requirements and helps to maintain low maintenance and future upgrade costs.

  3. FEDIX on-line information service: Design, develop, test, and implement an on-line research and education information service. Annual status report, September 1992--August 1993

    SciTech Connect

    Rodman, J.A.

    1993-08-01

    Federal Information Exchange, Inc. (FIE) is a diversified information services company that is recognized as the major electronic link between the higher education community and the Federal government in the field of research administration. FIE provides a range of information related services to the government, academic and private sectors, including database management, software development and technical support. FEDIX is the on-line information service designed, developed and implemented by FIE to accomplish the following objectives: (1). Broaden the participation of the education community in Federal research and education programs by providing free and unrestricted on-line access to information from all participating Federal agencies; and (2). Provide the education community with on-line access to a single keyword-searchable system for research and educational funding opportunities at the participating Federal agencies.

  4. Foreign Service Line of Duty Death Gratuity Act of 2011

    THOMAS, 112th Congress

    Rep. West, Allen B. [R-FL-22

    2011-09-09

    10/03/2011 Referred to the Subcommittee on Federal Workforce, U.S. Postal Service, and Labor Policy . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  5. Foreign Service Line of Duty Death Gratuity Act of 2011

    THOMAS, 112th Congress

    Rep. West, Allen B. [R-FL-22

    2011-09-09

    10/03/2011 Referred to the Subcommittee on Federal Workforce, U.S. Postal Service, and Labor Policy . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Foreign Service Line of Duty Death Gratuity Act of 2011

    THOMAS, 112th Congress

    Rep. West, Allen B. [R-FL-22

    2011-09-09

    House - 10/03/2011 Referred to the Subcommittee on Federal Workforce, U.S. Postal Service, and Labor Policy . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  7. Use of Physical Therapy Following Total Knee Replacement Surgery: Implications of Orthopedic Surgeons' Ownership of Physical Therapy Services.

    PubMed

    Mitchell, Jean M; Reschovsky, James D; Reicherter, Elizabeth Anne

    2016-10-01

    To examine whether the course of physical therapy treatments received by patients who undergo total knee replacement (TKR) surgery differs depending on whether the orthopedic surgeon has a financial stake in physical therapy services. Sample of Medicare beneficiaries who underwent TKR surgery during the years 2007-2009. We used regression analysis to evaluate the effect of physician self-referral on the following outcomes: (1) time from discharge to first physical therapy visit; (2) episode length; (3) number of physical therapy visits per episode; (4) number of physical therapy service units per episode; and (5) number of physical therapy services per episode expressed in relative value units. TKR patients who underwent physical therapy treatment at a physician-owned clinic received on average twice as many physical therapy visits (8.3 more) than patients whose TKR surgery was performed by a orthopedic surgeon who did not self-refer physical therapy services (p < .001). Regression-adjusted results show that TKR patients treated at physician-owned clinics received almost nine fewer physical therapy service units during an episode compared with patients treated by nonself-referring providers (p < .001). In relative value units, this difference was 4 (p < .001). In contrast, episodes where the orthopedic surgeon owner does not profit from physical therapy services rendered to the patient look virtually identical to episodes where the TKR surgery was performed by a surgeon nonowner. Physical therapists not involved with physician-owned clinics saw patients for fewer visits, but the composition of physical therapy services rendered during each visit included more individualized therapeutic exercises. © Health Research and Educational Trust.

  8. The proposed planning method as a parallel element to a real service system for dynamic sharing of service lines.

    PubMed

    Klampfer, Saša; Chowdhury, Amor

    2015-07-01

    This paper presents a solution to the bottleneck problem with dynamic sharing or leasing of service capacities. From this perspective the use of the proposed method as a parallel element in service capacities sharing is very important, because it enables minimization of the number of interfaces, and consequently of the number of leased lines, with a combination of two service systems with time-opposite peak loads. In this paper we present a new approach, methodology, models and algorithms which solve the problems of dynamic leasing and sharing of service capacities.

  9. Bearing repair services offer a cost-effective alternative to expensive replacement

    SciTech Connect

    2009-02-15

    The article, based on a presentation during MINExpo 2008, explains how advancement is bearing design, material, maintenance and repair methods have greatly improved the potential for and popularity of bearing repair as an effective way to extend bearing life. The Trinken Co. offers a variety of service options including repair, recertification, reconditioning and remanufacturing. Benefits of a quality repair program are outlined. 2 photos.

  10. On-line Career Services: A Brief Update.

    ERIC Educational Resources Information Center

    Kirk, James J.; Murrin, Jennifer

    Numerous web sites on the Internet are dedicated to academic and career planning, market information, market trends, and job banks. A majority of the human resource management services offered on the Internet deal with the area of recruiting. The job placement activities emphasize searching vast databases of job openings and submitting resumes.…

  11. On-Line Bibliographic Search Services. SPEC Kit 62.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This Systems and Procedures Exchange Center (SPEC) kit examines the current state of online services based upon the experiences of a select number of Association of Research Libraries (ARL) member libraries in the United States and Canada. Many of the kit documents were obtained during a survey of eight private institutions conducted for Duke…

  12. On-Line Reference Services in Public Libraries.

    ERIC Educational Resources Information Center

    Kusack, James M.

    1979-01-01

    A survey of 34 of the largest public library systems, each serving at least 500,000 people, showed: (1) minority offer online database services; (2) cost is major prohibiting factor; (3) New York Times Information Bank is most popular database; (4) fee structures vary; and (5) business organizations are most frequent users. (JD)

  13. Report: Controls and Oversight Needed to Improve Administration of EPA’s Customer Service Lines

    EPA Pesticide Factsheets

    Report #13-P-0432, September 26, 2013. The EPA has a variety of resources—including telephone hotlines, Web clearinghouses, and other online reference information—which the OIG has categorized as customer service lines (CSLs).

  14. Experiences of 24-hour advice line services: a framework for good practice and meeting NICE guidelines.

    PubMed

    Yardley, Sarah J; Codling, Jan; Roberts, Dai; O Donnell, Valerie; Taylor, Sue

    2009-06-01

    This article presents a framework for the practical implementation of a 24-hour specialist palliative care advice line, illustrated by two case examples from the authors' experience. In the UK, National Institute for Health and Clinical Excellence guidance requires provision of 24-hour access to specialist palliative care advice for healthcare professionals and carers regardless of a patient's location. Effective implementation of a telephone advice line for specialist advice is one approach to addressing the current variability in palliative care service provision, both in the UK and elsewhere. The authors were unable to identify a model with documentation for ensuring adequate clinical governance of an advice line in the literature and so present their own. The accompanying case examples demonstrate the difference between 'evolution of services by demand' and taking a systemic approach to service design. Key recommendations for practice are outlined for an effective advice line service which incorporates training and education into the clinical governance structures of the host organization.

  15. Application and evaluation of foreign systems for lining gas distribution service pipes

    SciTech Connect

    Kramer, S.R.; Gauthier, S.W.; Spivey, A.J.

    1996-08-01

    This paper summarizes a Gas Research Institute program to test and evaluate trenchless rehabilitation technologies for lining gas distribution service pipes. The technical approach for the program was to evaluate foreign service lining systems, determine industry needs versus system capabilities, conduct controlled laboratory evaluations, and perform field evaluations. Two techniques in use at Japanese and British gas companies were investigated, and trials were conducted at six U.S. gas utilities. The reverse lining method of the Japanese utilities was successfully applied to service pipes of 1 to 4 inch diameter for lengths up to 90 feet. The RENU live insertion method used by British Gas is also a potentially viable option for service line renewal. 10 figs., 3 tabs.

  16. Reengineering a surgical service line: focusing on core process improvement.

    PubMed

    Kelly, D L; Pestotnik, S L; Coons, M C; Lelis, J W

    1997-01-01

    Integrating principles from a variety of theory has led to the development of a conceptual framework for reengineering in a clinical care delivery setting to improve the value of services provided to the customer. A conceptual framework involving the identification of three high level core processes to reengineer can provide clarity and focus for clinicians to begin directing reengineering efforts. Those core processes are: clinical management of the patient's medical needs, patient operational processes to support the clinical processes, and administrative decision-making processes to support the implementation of the clinical and operational processes. Improvement in any one of these areas has the potential to increase value, but the concurrent targeting of these core processes for reengineering has provided a synergy that has accelerated the achievement of the desired outcomes in the area of surgical services.

  17. The impact of a 'resident replacement' nurse practitioner on an Academic Pediatric Neurosurgical service.

    PubMed

    Holleman, Judie; Johnson, Amanda; Frim, David M

    2010-01-01

    The introduction of 80-hour workweek limitations has challenged resident training programs with creative scheduling while maintaining comprehensive training experiences. The work hour restrictions may be more adaptable to a medical service, but have been very challenging to an academic surgical program. The particular challenges include maximizing academic learning opportunities, operating room experiences and direct bedside patient care while adhering to the 80-hour restriction. This paper examines the addition of a pediatric nurse practitioner (NP) to a pediatric neurosurgical academic program in response to the resident work hour restrictions. A survey questionnaire asking for responses to questions on a 1-10 rating scale was distributed to physicians, nurses and allied care providers approximately 1 year after addition of the NP. Participants were asked to rate satisfaction with the service's availability, responsiveness and assessment of patient clinical satisfaction prior to the addition of the NP and at the time of questionnaire distribution. In addition, the hospital paging log was reviewed over a several-month epoch before and after addition of the NP. Finally, the number of quality assurance sentinel events was reviewed for the year prior to and the year after the initiation of the NP program. The satisfaction scores in all categories, including overall satisfaction, significantly improved (p < 0.001) after the addition of the NP to the neurosurgery service. Also, during the NP on-duty coverage hours, the number of paging calls received by the residents was reduced commensurate to the large number of calls received by the NP. This change was presumed to be due to the confidence of other services in obtaining a timely and appropriate response. Finally, the number of sentinel event reports remained stable. The addition of an NP in response to resident training changes has been a positive influence on satisfaction with the pediatric neurosurgical service

  18. Evaluation of Hose in Hose Transfer Line Service Life for Hanford's Interim Stabilization Program

    SciTech Connect

    TORRES, T.D.

    2000-08-24

    RPP-6153, Engineering Task Plan for Hose-in-Hose Transfer System for the Interim Stabilization Program, defines the programmatic goals, functional requirements, and technical criteria for the development and subsequent installation of transfer line equipment to support Hanford's Interim Stabilization Program. RPP-6028, Specification for Hose in Hose Transfer Lines for Hanford's Interim Stabilization Program, has been issued to define the specific requirements for the design, manufacture, and verification of transfer line assemblies for specific waste transfer applications. Included in RPP-6028 are tables defining the chemical constituents of concern to which transfer lines will be exposed. Current Interim Stabilization Program planning forecasts that the at-grade transfer lines will be required to convey pumpable waste for as much as three years after commissioning. Prudent engineering dictates that the equipment placed in service have a working life in excess of this forecasted time period, with some margin to allow for future adjustments to the planned schedule. This document evaluates the effective service life of the Hose-in-Hose Transfer Lines, based on information submitted by the manufacturer and published literature. The effective service life of transfer line assemblies is a function of several factors. Foremost among these are process fluid characteristics, ambient environmental conditions, and the manufacturer's stated shelf life. This evaluation examines the manufacturer's certification of shelf life, the manufacturer's certifications of chemical compatibility with waste, and published literature on the effects of exposure to ionizing radiation on the mechanical properties of elastomeric materials to evaluate transfer line service life.

  19. Connecting the dots: using 'big data' to build an efficient, integrated service line.

    PubMed

    Golberg, Dana; Leonard, Robert; McEnroe, Sean; McDonald, Jeff

    2015-08-01

    As seen in the case of musculoskeletal care, the broad steps hospitals and health systems should take to optimize service lines include: Understanding their market's demand for services. Guiding patients through integrated, patient-centric care. Taking patient engagement to the next level.

  20. 47 CFR 69.157 - Line port costs in excess of basic, analog service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Line port costs in excess of basic, analog service. 69.157 Section 69.157 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Computation of Charges for Price Cap Local Exchange Carriers...

  1. 76 FR 52731 - On-Line Complaint Form for Service-Related Issues in Air Transportation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... Office of the Secretary On-Line Complaint Form for Service-Related Issues in Air Transportation AGENCY... public to electronically submit aviation service-related complaints against air carriers. DATES: Comments... U.S.C., Subtitle VII, to investigate and enforce consumer protection and civil rights laws...

  2. Hospital takes customer service to new level, sees positive effect on bottom line.

    PubMed

    1997-06-01

    Service with a smile boosts bottom line. Treating co-workers and patients like guests is the linchpin of a whole new philosophy at Bradley Memorial Hospital in Cleveland, TN. Administrators there insist a host of new customer service programs, from cap and gown graduation ceremonies to bunny bucks, has resulted in dramatic financial improvements and more satisfied patients and staff.

  3. The beginning of a structural reform: reorganising the front line of a mental health service.

    PubMed

    Tobin, M; Yeo, F; Chen, L

    2000-01-01

    National and State priorities for mental health services have directed emphasis towards early intervention and prevention. One of the key priorities is to ensure that entry to mental health services is efficient, effective and accountable. This study describes the process of restructuring the front line of a large and complex mental health service. Adopting the total quality management approach, all stakeholders in the service collaboratively developed a single set of protocols and guidelines to achieve standardisation of documentation, assessment of risks and urgency, and to improve the overall quality of the service.

  4. Veterans Crisis Line Callers With and Without Prior VHA Service Use

    PubMed Central

    Britton, Peter C.; Kopacz, Marek S.; Stephens, Brady; Bossarte, Robert M.

    2016-01-01

    This study examines differences between Veterans with and without prior Veterans Health Administration service use who received a clinical referral from the Veterans' Crisis Line. Approximately 91% of Veterans had a history of service use and 9% did not. Callers with prior service use were older, had more mental health disorders, made in-person contact more quickly, and used more outpatient mental healthcare. Those without prior service use were younger, had more mental health problems, and presented for care later. Callers with suicide-related diagnoses had high rates of service contact. These groups represent different subpopulations with unique healthcare needs and practices. PMID:26649615

  5. Seeking an optimal renal replacement therapy for the chronic kidney disease epidemic: the case for on-line hemodiafiltration.

    PubMed

    Gatti, Emanuele; Ronco, Claudio

    2011-01-01

    The prevalence of chronic kidney disease (CKD) can be expected to increase dramatically in the foreseeable future, with suggestions that it has already reached epidemic proportions. The inadequate supply of donor organs, aggravated by an aging patient population, necessitates provision of sustainable dialysis treatment modalities. These treatment modalities must not only be of established clinical efficacy and effectiveness, but must simultaneously circumvent any potential treatment disparities due to geographical, social or other concurring factors. Home therapies might represent a partial solution to the complex issue of seeking optimal strategies to cope with the CKD epidemic. However, self-care renal replacement therapy (RRT), such as peritoneal dialysis (PD) and home therapies, can only be applied to a limited portion of the CKD population. Consequently, in preparation for coping with this CKD epidemic, specific large-scale plans need to be made that involve optimization of treatments already in use for the majority of the population requiring RRT, e.g. hemodialysis (HD). Extracorporeal chronic HD relies heavily on technology for its clinical success. Like the choice of the treatment modality and the complete medical approach to CKD patient care, the particular selection of the various components of the extracorporeal circuit has a significant impact on the well-being and survival of the patients. We present a medical-technological assessment of how best to treat vast numbers of dialysis patients under the financial restraints that are predicted to become even more severe as CKD entrenches itself as a more 'permanent epidemic'. A treatment modality is proposed that optimally addresses--and resolves--the debilitating effects of uremia, as well as of key clinical conditions closely linked to it. This treatment modality successfully tackles the issues of patient well-being, efficacy, effectiveness, safety and patient-nursing staff convenience--all in relation to

  6. On Line Service Composition in the Integrated Clinical Environment for eHealth and Medical Systems.

    PubMed

    García-Valls, Marisol; Touahria, Imad Eddine

    2017-06-08

    Medical and eHealth systems are progressively realized in the context of standardized architectures that support safety and ease the integration of the heterogeneous (and often proprietary) medical devices and sensors. The Integrated Clinical Environment (ICE) architecture appeared recently with the goal of becoming a common framework for defining the structure of the medical applications as concerns the safe integration of medical devices and sensors. ICE is simply a high level architecture that defines the functional blocks that should be part of a medical system to support interoperability. As a result, the underlying communication backbone is broadly undefined as concerns the enabling software technology (including the middleware) and associated algorithms that meet the ICE requirements of the flexible integration of medical devices and services. Supporting the on line composition of services in a medical system is also not part of ICE; however, supporting this behavior would enable flexible orchestration of functions (e.g., addition and/or removal of services and medical equipment) on the fly. iLandis one of the few software technologies that supports on line service composition and reconfiguration, ensuring time-bounded transitions across different service orchestrations; it supports the design, deployment and on line reconfiguration of applications, which this paper applies to service-based eHealth domains. This paper designs the integration between ICE architecture and iLand middleware to enhance the capabilities of ICE with on line service composition and the time-bounded reconfiguration of medical systems based on distributed services. A prototype implementation of a service-based eHealth system for the remote monitoring of patients is described; it validates the enhanced capacity of ICE to support dynamic reconfiguration of the application services. Results show that the temporal cost of the on line reconfiguration of the eHealth application is bounded

  7. On Line Service Composition in the Integrated Clinical Environment for eHealth and Medical Systems

    PubMed Central

    García-Valls, Marisol; Touahria, Imad Eddine

    2017-01-01

    Medical and eHealth systems are progressively realized in the context of standardized architectures that support safety and ease the integration of the heterogeneous (and often proprietary) medical devices and sensors. The Integrated Clinical Environment (ICE) architecture appeared recently with the goal of becoming a common framework for defining the structure of the medical applications as concerns the safe integration of medical devices and sensors. ICE is simply a high level architecture that defines the functional blocks that should be part of a medical system to support interoperability. As a result, the underlying communication backbone is broadly undefined as concerns the enabling software technology (including the middleware) and associated algorithms that meet the ICE requirements of the flexible integration of medical devices and services. Supporting the on line composition of services in a medical system is also not part of ICE; however, supporting this behavior would enable flexible orchestration of functions (e.g., addition and/or removal of services and medical equipment) on the fly. iLandis one of the few software technologies that supports on line service composition and reconfiguration, ensuring time-bounded transitions across different service orchestrations; it supports the design, deployment and on line reconfiguration of applications, which this paper applies to service-based eHealth domains. This paper designs the integration between ICE architecture and iLand middleware to enhance the capabilities of ICE with on line service composition and the time-bounded reconfiguration of medical systems based on distributed services. A prototype implementation of a service-based eHealth system for the remote monitoring of patients is described; it validates the enhanced capacity of ICE to support dynamic reconfiguration of the application services. Results show that the temporal cost of the on line reconfiguration of the eHealth application is bounded

  8. Evaluation of foreign systems for lining gas distribution service pipes. Topical report, August 1994-March 1996

    SciTech Connect

    Kramer, S.R.

    1997-01-01

    Jason Consultants International, Inc. under the sponsorship of the Gas Research Institute (GRI) conducted a program to test and evaluate promising trenchless rehabilitation technologies for lining gas distribution service pipes that were developed outside of the U.S., particularly in Japan and Europe. To begin the program, a group of gas industry executives traveled to Japan to evaluate technologies in use at Osaka Gas and Tokyo Gas. Several systems were identified which could be applied to service piping systems in the U.S. This included the Paltem Reverse Lining System, NEXT Technique and the HIT system. Actual field trials were performed at U.S. gas utilities using the Paltem Reverse Lining System from October 1995 to March 1996. This system can be applied successfully to service pipes ranging in diameter from 1 to 4 inches and lengths up to 90 feet. A three-person crew can line at least three services per day. The Paltem Reverse Lining System can handle complex service pipe configurations including bends with minimal excavations. Due to budgetary constraints at GRI and problems with technology transfer, it was not possible to conduct trials using the other identified service renewal systems.

  9. JPL's On-Line Solar System Data Service

    NASA Astrophysics Data System (ADS)

    Giorgini, J. D.; Yeomans, D. K.; Chamberlin, A. B.; Chodas, P. W.; Jacobson, R. A.; Keesey, M. S.; Lieske, J. H.; Ostro, S. J.; Standish, E. M.; Wimberly, R. N.

    1996-09-01

    Numerous data products from the JPL ephemeris team are being made available via an interactive telnet computer service and separate web page. For over 15,000 comets and asteroids, 60 natural satellites, and 9 planets, users with an Internet connection can easily create and download information 24 hours a day, 7 days a week. These data include customized, high precision ephemerides, orbital and physical characteristics, and search-lists of comets and asteroids that match combinations of up to 39 different parameters. For each body, the user can request computation of more than 70 orbital and physical quantities. Ephemerides output can be generated in ICRF/J2000.0 and FK4/1950.0 reference frames with TDB, TT, or UTC timescales, as appropriate, at user specified intervals. Computed tables are derived from the same ephemerides used at JPL for radar astronomy and spacecraft navigation. The dynamics and computed observables include relativistic effects. Available ephemeris time spans currently range from A.D. 1599-2200 for the planets to a few decades for the satellites, comets and asteroids. Information on the interference from sunlight and moonlight is available. As an example of a few of the features available, we note that a user could easily generate information on satellite and planetary magnitudes, illuminated fractions, and the planetographic longitudes and latitudes of their centers and sub-solar points as seen from a particular observatory location on Earth. Satellite transits, occultations and eclipses are available as well. The resulting ASCII tables can be transferred to the user's host computer via e-mail, ftp, or kermit protocols. For those who have WWW access, the telnet solar system ephemeris service will be one feature of the JPL solar system web page. This page will provide up-to-date physical and orbital characteristics as well as current and predicted observing opportunities for all solar system bodies. Close Earth approaches and radar observations

  10. Information logistics: A production-line approach to information services

    NASA Technical Reports Server (NTRS)

    Adams, Dennis; Lee, Chee-Seng

    1991-01-01

    Logistics can be defined as the process of strategically managing the acquisition, movement, and storage of materials, parts, and finished inventory (and the related information flow) through the organization and its marketing channels in a cost effective manner. It is concerned with delivering the right product to the right customer in the right place at the right time. The logistics function is composed of inventory management, facilities management, communications unitization, transportation, materials management, and production scheduling. The relationship between logistics and information systems is clear. Systems such as Electronic Data Interchange (EDI), Point of Sale (POS) systems, and Just in Time (JIT) inventory management systems are important elements in the management of product development and delivery. With improved access to market demand figures, logisticians can decrease inventory sizes and better service customer demand. However, without accurate, timely information, little, if any, of this would be feasible in today's global markets. Information systems specialists can learn from logisticians. In a manner similar to logistics management, information logistics is concerned with the delivery of the right data, to the ring customer, at the right time. As such, information systems are integral components of the information logistics system charged with providing customers with accurate, timely, cost-effective, and useful information. Information logistics is a management style and is composed of elements similar to those associated with the traditional logistics activity: inventory management (data resource management), facilities management (distributed, centralized and decentralized information systems), communications (participative design and joint application development methodologies), unitization (input/output system design, i.e., packaging or formatting of the information), transportations (voice, data, image, and video communication systems

  11. Research influence on antimalarial drug policy change in Tanzania: case study of replacing chloroquine with sulfadoxine-pyrimethamine as the first-line drug.

    PubMed

    Mubyazi, Godfrey M; Gonzalez-Block, Miguel A

    2005-10-20

    Research is an essential tool in facing the challenges of scaling up interventions and improving access to services. As in many other countries, the translation of research evidence into drug policy action in Tanzania is often constrained by poor communication between researchers and policy decision-makers, individual perceptions or attitudes towards the drug and hesitation by some policy decision-makers to approve change when they anticipate possible undesirable repercussions should the policy change as proposed. Internationally, literature on the role of researchers on national antimalarial drug policy change is limited. To describe the (a) role of researchers in producing evidence that influenced the Tanzanian government replace chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) as the first-line drug and the challenges faced in convincing policy-makers, general practitioners, pharmaceutical industry and the general public on the need for change (b) challenges ahead before a new drug combination treatment policy is introduced in Tanzania. In-depth interviews were held with national-level policy-makers, malaria control programme managers, pharmaceutical officers, general medical practitioners, medical research library and publications officers, university academicians, heads of medical research institutions and district and regional medical officers. Additional data were obtained through a review of malaria drug policy documents and participant observations were also done. In year 2001, the Tanzanian Government officially changed its malaria treatment policy guidelines whereby CQ--the first-line drug for a long time was replaced with SP. This policy decision was supported by research evidence indicating parasite resistance to CQ and clinical CQ treatment failure rates to have reached intolerable levels as compared to SP and amodiaquine (AQ). Research also indicated that since SP was also facing rising resistance trend, the need for a more effective drug was

  12. Research influence on antimalarial drug policy change in Tanzania: case study of replacing chloroquine with sulfadoxine-pyrimethamine as the first-line drug

    PubMed Central

    Mubyazi, Godfrey M; Gonzalez-Block, Miguel A

    2005-01-01

    Introduction Research is an essential tool in facing the challenges of scaling up interventions and improving access to services. As in many other countries, the translation of research evidence into drug policy action in Tanzania is often constrained by poor communication between researchers and policy decision-makers, individual perceptions or attitudes towards the drug and hesitation by some policy decision-makers to approve change when they anticipate possible undesirable repercussions should the policy change as proposed. Internationally, literature on the role of researchers on national antimalarial drug policy change is limited. Objectives To describe the (a) role of researchers in producing evidence that influenced the Tanzanian government replace chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) as the first-line drug and the challenges faced in convincing policy-makers, general practitioners, pharmaceutical industry and the general public on the need for change (b) challenges ahead before a new drug combination treatment policy is introduced in Tanzania. Methods In-depth interviews were held with national-level policy-makers, malaria control programme managers, pharmaceutical officers, general medical practitioners, medical research library and publications officers, university academicians, heads of medical research institutions and district and regional medical officers. Additional data were obtained through a review of malaria drug policy documents and participant observations were also done. Results In year 2001, the Tanzanian Government officially changed its malaria treatment policy guidelines whereby CQ – the first-line drug for a long time was replaced with SP. This policy decision was supported by research evidence indicating parasite resistance to CQ and clinical CQ treatment failure rates to have reached intolerable levels as compared to SP and amodiaquine (AQ). Research also indicated that since SP was also facing rising resistance trend

  13. CRISPR/Cas9-induced Targeted Mutagenesis and Gene Replacement to Generate Long-shelf Life Tomato Lines.

    PubMed

    Yu, Qing-Hui; Wang, Baike; Li, Ning; Tang, Yaping; Yang, Shengbao; Yang, Tao; Xu, Juan; Guo, Chunmiao; Yan, Peng; Wang, Qiang; Asmutola, Patiguli

    2017-09-19

    Quickly and precisely gain genetically enhanced breeding elites with value-adding performance traits is desired by the crop breeders all the time. The present of gene editing technologies, especially the CRISPR/Cas9 system with the capacities of efficiency, versatility and multiplexing provides a reasonable expectation towards breeding goals. For exploiting possible application to accelerate the speed of process at breeding by CRISPR/Cas9 technology, in this study, the Agrobacterium tumefaciens-mediated CRISPR/Cas9 system transformation method was used for obtaining tomato ALC gene mutagenesis and replacement, in absence and presence of the homologous repair template. The average mutation frequency (72.73%) and low replacement efficiency (7.69%) were achieved in T0 transgenic plants respectively. None of homozygous mutation was detected in T0 transgenic plants, but one plant carry the heterozygous genes (Cas9/*-ALC/alc) was stably transmitted to T1 generations for segregation and genotyping. Finally, the desired alc homozygous mutants without T-DNA insertion (*/*-alc/alc) in T1 generations were acquired and further confirmed by genotype and phenotype characterization, with highlight of excellent storage performance, thus the recessive homozygous breeding elites with the character of long-shelf life were generated. Our results support that CRISPR/Cas9-induced gene replacement via HDR provides a valuable method for breeding elite innovation in tomato.

  14. Association between children's blood lead levels, lead service lines, and water disinfection, Washington, DC, 1998-2006.

    PubMed

    Brown, Mary Jean; Raymond, Jaime; Homa, David; Kennedy, Chinaro; Sinks, Thomas

    2011-01-01

    Evaluate the effect of changes in the water disinfection process, and presence of lead service lines (LSLs), on children's blood lead levels (BLLs) in Washington, DC. Three cross-sectional analyses examined the relationship of LSL and changes in water disinfectant with BLLs in children <6 years of age. The study population was derived from the DC Childhood Lead Poisoning Prevention Program blood lead surveillance system of children who were tested and whose blood lead test results were reported to the DC Health Department. The Washington, DC Water and Sewer Authority (WASA) provided information on LSLs. The final study population consisted of 63,854 children with validated addresses. Controlling for age of housing, LSL was an independent risk factor for BLLs ≥ 10 μg/dL, and ≥ 5 μg/dL even during time periods when water levels met the US Environmental Protection Agency (EPA) action level of 15 parts per billion (ppb). When chloramine alone was used to disinfect water, the risk for BLL in the highest quartile among children in homes with LSL was greater than when either chlorine or chloramine with orthophosphate was used. For children tested after LSLs in their houses were replaced, those with partially replaced LSL were >3 times as likely to have BLLs ≥ 10 μg/dL versus children who never had LSLs. LSLs were a risk factor for elevated BLLs even when WASA met the EPA water action level. Changes in water disinfection can enhance the effect of LSLs and increase lead exposure. Partially replacing LSLs may not decrease the risk of elevated BLLs associated with LSL exposure. Copyright © 2010 Elsevier Inc. All rights reserved.

  15. Research for the Working Method of Live Replacing the L-type Insulator String on ±800kV DC Transmission Lines

    NASA Astrophysics Data System (ADS)

    Li, Jinliang; Wang, Zhigang; Lei, Dongyun; Yang, Miao; Xia, Zengming; Xiang, Yun; Yan, Yu; Liu, Zhiguo

    2017-07-01

    It would be hard to be repaired in the case of a power outage if the ±800kV ultra high voltage DC (UHVDC) transmission line was put into operation, so live working is the guarantee for its security and stability. Insulator strings of duplex L-type are widely used in UHVDC small angle towers. In the meantime, the tower structure and the insulator strings’ arrangement type is different than the V-type. In order to ensure the security and stability of the transmission line, this paper presents a method of live replacing the duplex L-type insulators based on the actual parameter of the UHVDC L tower type and develops apparatus as a complementary supporting by mechanics analysis. In order to ensure the safety of working staff, the safe distance and combined gap of the hanging basket method are checked. Safety precautions are also proposed in the paper by the calculation of body surface field strength of the persons doing live working in the finite element method. It is shown by the field application that the live working task of replacing the L-type insulator strings can be accomplished successfully by the method put forward in this paper, which provides reference for the following live working on the UHV transmission line.

  16. Towards On-Line Services Based on a Holistic Analysis of Human Activities

    NASA Technical Reports Server (NTRS)

    Clancey, William J.

    2004-01-01

    Very often computer scientists view computerization of services in terms of the logistics of human-machine interaction, including establishing a contract, accessing records, and of course designing an interface. But this analysis often moves too quickly to tactical details, failing to frame the entire service in human terms, and not recognizing the mutual learning required to define and relate goals, constraints, and the personalized value of available services. In particular, on-line services that "computerize communication" can be improved by constructing an activity model of what the person is trying to do, not just filtering, comparing, and selling piece-meal services. For example, from the customer s perspective the task of an on-line travel service is not merely to establish confirmed reservations, but to have a complete travel plan, usually integrating many days of transportation, lodging, and recreation into a happy experience. The task of the travel agent is not merely "ticketing", but helping the customer understand what they want and providing services that will connect everything together in an enjoyable way.

  17. Peak Lead Levels and Diagnostics in Lead Service Lines Dominated by PbO2 - abstract

    EPA Science Inventory

    Multiple studies have presented “profiles” of water lead levels from tap to main through lead service lines (LSLs), in systems where the LSLs were coated with common Pb(II) corrosion solids. These Pb(II) solids were either actual Pb(II) minerals or Pb(II) sorbed onto other pipe ...

  18. Peak Lead Levels and Diagnostics in Lead Service Lines Dominated by PbO2 - abstract

    EPA Science Inventory

    Multiple studies have presented “profiles” of water lead levels from tap to main through lead service lines (LSLs), in systems where the LSLs were coated with common Pb(II) corrosion solids. These Pb(II) solids were either actual Pb(II) minerals or Pb(II) sorbed onto other pipe ...

  19. Veterans Crisis Line Callers With and Without Prior VHA Service Use.

    PubMed

    Britton, Peter C; Kopacz, Marek S; Stephens, Brady; Bossarte, Robert M

    2016-07-02

    This study examines differences between Veterans with and without prior Veterans Health Administration service use who received a clinical referral from the Veterans' Crisis Line. Differences between groups were identified using data taken from 13,444 calls and medical records. Approximately 91% of Veterans had a history of service use and 9% did not. Callers with prior service use were older, had more mental health disorders, made in-person contact more quickly, and used more outpatient mental healthcare. Those without prior service use were younger, had more mental health problems, and presented for care later. Callers with suicide-related diagnoses had high rates of service contact. These groups represent different subpopulations with unique healthcare needs and practices.

  20. A longitudinal analysis of the impact of hospital service line profitability on the likelihood of readmission.

    PubMed

    Navathe, Amol S; Volpp, Kevin G; Konetzka, R Tamara; Press, Matthew J; Zhu, Jingsan; Chen, Wei; Lindrooth, Richard C

    2012-08-01

    Quality of care may be linked to the profitability of admissions in addition to level of reimbursement. Prior policy reforms reduced payments that differentially affected the average profitability of various admission types. The authors estimated a Cox competing risks model, controlling for the simultaneous risk of mortality post discharge, to determine whether the average profitability of hospital service lines to which a patient was admitted was associated with the likelihood of readmission within 30 days. The sample included 12,705,933 Medicare Fee for Service discharges from 2,438 general acute care hospitals during 1997, 2001, and 2005. There was no evidence of an association between changes in average service line profitability and changes in readmission risk, even when controlling for risk of mortality. These findings are reassuring in that the profitability of patients' admissions did not affect readmission rates, and together with other evidence may suggest that readmissions are not an unambiguous quality indicator for in-hospital care.

  1. Identification and Reduction of Bottlenecks Concerning MICAP Re-Supply of F-16 Weapons System Avionics Line Replaceable Units

    DTIC Science & Technology

    1997-09-01

    developed by Eliyahu Goldratt ], is a continual improvement philosophy that focuses on the identification and management of constraints for organizational...FedEx U.S. Government Contract Services Guide. August 1996. 51 Goldratt , Eliyahu M. The Goal: A Process of Ongoing Improvement. Second Edition. North

  2. Extracting potential bus lines of Customized City Bus Service based on public transport big data

    NASA Astrophysics Data System (ADS)

    Ren, Yibin; Chen, Ge; Han, Yong; Zheng, Huangcheng

    2016-11-01

    Customized City Bus Service (CCBS) can reduce the traffic congestion and environmental pollution that caused by the increasing in private cars, effectively. This study aims to extract the potential bus lines and each line's passenger density of CCBS by mining the public transport big data. The datasets used in this study are mainly Smart Card Data (SCD) and bus GPS data of Qingdao, China, from October 11th and November 7th 2015. Firstly, we compute the temporal-origin-destination (TOD) of passengers by mining SCD and bus GPS data. Compared with the traditional OD, TOD not only has the spatial location, but also contains the trip's boarding time. Secondly, based on the traditional DBSCAN algorithm, we put forwards an algorithm, named TOD-DBSCAN, combined with the spatial-temporal features of TOD.TOD-DBSCAN is used to cluster the TOD trajectories in peak hours of all working days. Then, we define two variables P and N to describe the possibility and passenger destiny of a potential CCBS line. P is the probability of the CCBS line. And N represents the potential passenger destiny of the line. Lastly, we visualize the potential CCBS lines extracted by our procedure on the map and analyse relationship between potential CCBS lines and the urban spatial structure.

  3. Can CT pulmonary angiography replace ventilation-perfusion scans as a first line investigation for pulmonary emboli?

    PubMed

    McEwan, L; Gandhi, M; Andersen, J; Manthey, K

    1999-08-01

    A prospective study was performed to determine efficacy of diagnosis of pulmonary emboli by computed tomographic pulmonary angiography (CTPA) in patients who underwent both CTPA and ventilation-perfusion (V/Q) scanning. The results were compared with the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study in which conventional pulmonary angiography had been performed instead of CTPA. Forty-two of 161 (26%) patients had a positive CTPA compared with a 27% prevalence in the PIOPED population. Fourteen of 16 patients (87.5%) with high-probability V/Q scans also had a positive CTPA compared with 87% in PIOPED. Twelve of 40 patients (30%) with intermediate probability V/Q scans also had a positive CTPA compared with 34.7% in PIOPED, while 12 of 80 patients (15%) who had low-probability V/Q scans had positive CTPA compared with 14.5% in PIOPED. Four of 25 patients (16%) with normal V/Q scans had positive CTPA compared with 0% in PIOPED. While the present study size was relatively small, the results compared favourably with PIOPED, suggesting that equivalent prevalence of clot was being detected using CTPA. This result, together with the cost considerations, has led us to replace V/Q scanning with CTPA for investigation of the majority of cases of suspected, acute pulmonary emboli.

  4. 75 FR 2580 - Pioneer Industrial Railway Co.-Discontinuance of Service Exemption-Line in Peoria County, IL...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... Surface Transportation Board Pioneer Industrial Railway Co.--Discontinuance of Service Exemption--Line in Peoria County, IL; Central Illinois Railroad Company--Discontinuance of Service Exemption--Line in Peoria County, IL On December 29, 2009, Pioneer Industrial Railway Co. (PIRY) and Central Illinois...

  5. Locating Negative Decimals on the Number Line: Insights into the Thinking of Pre-Service Primary Teachers

    ERIC Educational Resources Information Center

    Widjaja, Wanty; Stacey, Kaye; Steinle, Vicki

    2011-01-01

    This paper explores misconceptions of the number line which are revealed when pre-service primary teachers locate negative decimals on a number line. Written test responses from 94 pre-service primary teachers provide an initial data source which is supplemented by group responses to worksheets completed during a lesson and individual interviews.…

  6. 49 CFR 1242.76 - Administration; pickup and delivery, marine line haul, and rail substitute service; loading...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Administration; pickup and delivery, marine line haul, and rail substitute service; loading, unloading and local marine; protective services; freight... Operating Expenses-Transportation § 1242.76 Administration; pickup and delivery, marine line haul, and...

  7. 49 CFR 1242.76 - Administration; pickup and delivery, marine line haul, and rail substitute service; loading...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Administration; pickup and delivery, marine line haul, and rail substitute service; loading, unloading and local marine; protective services; freight... Operating Expenses-Transportation § 1242.76 Administration; pickup and delivery, marine line haul, and...

  8. 49 CFR 1242.76 - Administration; pickup and delivery, marine line haul, and rail substitute service; loading...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Administration; pickup and delivery, marine line haul, and rail substitute service; loading, unloading and local marine; protective services; freight... Operating Expenses-Transportation § 1242.76 Administration; pickup and delivery, marine line haul, and...

  9. Locating Negative Decimals on the Number Line: Insights into the Thinking of Pre-Service Primary Teachers

    ERIC Educational Resources Information Center

    Widjaja, Wanty; Stacey, Kaye; Steinle, Vicki

    2011-01-01

    This paper explores misconceptions of the number line which are revealed when pre-service primary teachers locate negative decimals on a number line. Written test responses from 94 pre-service primary teachers provide an initial data source which is supplemented by group responses to worksheets completed during a lesson and individual interviews.…

  10. Continuous cell lines from the Muscovy duck as potential replacement for primary cells in the production of avian vaccines.

    PubMed

    Jordan, Ingo; John, Katrin; Höwing, Kristin; Lohr, Verena; Penzes, Zoltán; Gubucz-Sombor, Erzsébet; Fu, Yan; Gao, Peng; Harder, Timm; Zádori, Zoltán; Sandig, Volker

    2016-01-01

    Veterinary vaccines contribute to food security, interrupt zoonotic transmissions, and help to maintain overall health in livestock. Although vaccines are usually cost-effective, their adoption depends on a multitude of factors. Because poultry vaccines are usually given to birds with a short life span, very low production cost per dose is one important challenge. Other hurdles are to ensure a consistent and reliable supply of very large number of doses, and to have flexible production processes to accommodate a range of different pathogens and dosage requirements. Most poultry vaccines are currently being produced on primary avian cells derived from chicken or waterfowl embryos. This production system is associated with high costs, logistic complexities, rigid intervals between harvest and production, and supply limitations. We investigated whether the continuous cell lines Cairina retina and CR.pIX may provide a substrate independent of primary cell cultures or embryonated eggs. Viruses examined for replication in these cell lines are strains associated with, or contained in vaccines against egg drop syndrome, Marek's disease, Newcastle disease, avian influenza, infectious bursal disease and Derzsy's disease. Each of the tested viruses required the development of unique conditions for replication that are described here and can be used to generate material for in vivo efficacy studies and to accelerate transfer of the processes to larger production volumes.

  11. A Dedicated Inferior Vena Cava Filter Service Line: How to Optimize Your Practice.

    PubMed

    Karp, Jennifer K; Desai, Kush R; Salem, Riad; Ryu, Robert K; Lewandowski, Robert J

    2016-06-01

    Despite the increased placement of retrievable inferior vena cava filters (rIVCFs), efforts to remove these devices are not commensurate. The majority of rIVCFs are left in place beyond their indicated usage, and often are retained permanently. With a growing understanding of the clinical issues associated with these devices, the United States Food and Drug Administration (FDA) has prompted clinicians to remove rIVCF when they are no longer indicated. However, major obstacles exist to filter retrieval, chief among them being poor clinical follow-up. The establishment of a dedicated IVC filter service line, or clinic, has been shown to improve filter retrieval rates. Usage of particular devices, specifically permanent versus retrievable filters, is enhanced by prospective physician consultation. In this article, the rationale behind a dedicated IVC filter service line is presented as well as described the structure and activities of the authors' IVC filter clinic; supporting data will also be provided when appropriate.

  12. A Dedicated Inferior Vena Cava Filter Service Line: How to Optimize Your Practice

    PubMed Central

    Karp, Jennifer K.; Desai, Kush R.; Salem, Riad; Ryu, Robert K.; Lewandowski, Robert J.

    2016-01-01

    Despite the increased placement of retrievable inferior vena cava filters (rIVCFs), efforts to remove these devices are not commensurate. The majority of rIVCFs are left in place beyond their indicated usage, and often are retained permanently. With a growing understanding of the clinical issues associated with these devices, the United States Food and Drug Administration (FDA) has prompted clinicians to remove rIVCF when they are no longer indicated. However, major obstacles exist to filter retrieval, chief among them being poor clinical follow-up. The establishment of a dedicated IVC filter service line, or clinic, has been shown to improve filter retrieval rates. Usage of particular devices, specifically permanent versus retrievable filters, is enhanced by prospective physician consultation. In this article, the rationale behind a dedicated IVC filter service line is presented as well as described the structure and activities of the authors' IVC filter clinic; supporting data will also be provided when appropriate. PMID:27247479

  13. [Strategic lines for the guidance of health services with a future perspective].

    PubMed

    Moreu, Francesc; Bohigas, Lluís; Fusté, Josep

    2008-12-01

    The Health Map of Catalonia includes a set of strategic lines which constitute a framework for the alignment of objectives in the public healthcare system and which are elements of guidance in the evolution of the healthcare model with regard to the future. The strategic lines are grouped into 10 major themes which deal with the health policy and service policy (priorities and objectives of the system); the role of the citizens as protagonists; interaction between professionals and patients; comprehensive care and continuity in healthcare; collaboration between teams of professionals in multi-centre networks; professional development; information and communication technologies aiding in clinical decisions and relationships between professionals; the triumvirate of accessibility, quality and efficiency; the participation of citizens, institutions, professionals and organisations in the operation of services; and, finally, the assessment, to give an account of the above and take action.

  14. Evaluation of Hose in Hose Transfer Line Service Life for Hanfords Interim Stabilization Program

    SciTech Connect

    TORRES, T.D.

    2001-03-23

    RPP-6153, Engineering Task Plan for Hose-in-Hose Transfer System for the Interim Stabilization Program (Torres, 2000a), defines the programmatic goals, functional requirements, and technical criteria for the development and subsequent installation of waste transfer line equipment to support Hanford's Interim Stabilization Program. RPP-6028, Specification for Hose in Hose Transfer Lines for Hanford's Interim Stabilization Program (Torres, 2000b), has been issued to define the specific requirements for the design, manufacture, and verification of transfer line assemblies for specific waste transfer applications associated with Interim Stabilization. Included in RPP-6028 are tables defining the chemical constituents of concern to which transfer lines will be exposed. Current Interim Stabilization Program planning forecasts that the at-grade transfer lines will be required to convey pumpable waste for as much as three years after commissioning, RPP-6028 Section 3.2.7. Performance Incentive Number ORP-05 requires that all the Single Shell Tanks be Interim Stabilized by September 30, 2003. The Tri-Party Agreement (TPA) milestone M-41-00, enforced by a federal consent decree, requires all the Single Shell Tanks to be Interim stabilized by September 30, 2004. By meeting the Performance Incentive the TPA milestone is met. Prudent engineering dictates that the equipment used to transfer waste have a life in excess of the forecasted operational time period, with some margin to allow for future adjustments to the planned schedule. This document evaluates the effective service life of the Hose-in-Hose Transfer Lines, based on information submitted by the manufacturer, published literature and calculations. The effective service life of transfer line assemblies is a function of several factors. Foremost among these are the hose material's resistance to the harmful effects of process fluid characteristics, ambient environmental conditions, exposure to ionizing radiation and the

  15. Recent changes in the GenBank On-line Service.

    PubMed Central

    Benton, D

    1990-01-01

    The GenBank On-line Service provides access to the GenBank and EMBL nucleic acid sequence databases and to the Swiss-Prot and GenPept protein sequence databases. Users can query the databases by sequence similarity and annotation keywords and retrieve entries of interest. This access is available through e-mail servers, anonymous FTP, anonymous interactive login, and login to established, password-protected, individual accounts. PMID:2326192

  16. Product-line administration: a framework for redefining medical record department services.

    PubMed

    Postal, S N

    1990-06-01

    Product-line administration is a viable approach for managing medical records services in an environment that demands high quantity and quality service levels. Product-line administration directs medical record department team members to look outside of the department and seek input from the customers it is intended to serve. The feedback received may be alarming at first, as the current state of products usually reveals a true lack of customer input. As the planning, defining, managing, and marketing phases are implemented, the road will not be easy and rewards will be slow to come. Product-line administration does not provide quick fixes, but it does provide long-term problem resolution as products are refined and new products developed to meet customer needs and expectations. In addition to better meeting the needs of the department's external customers, the department's internal customers' needs and expectations will be addressed. The participative management approach will help nurture each team member's creativity. The team members will have the opportunity to reach their full potential while reaping the rewards and benefits of providing products and services that meet the needs and expectations of all department customers. The future of the health care industry promises more changes as the country moves toward some form of prospective payment in the ambulatory setting. Reactive management and the constant struggle to catch up can no longer be accepted as a management approach. It is imperative that the medical record department be viewed as a business with product lines composed of quality products. The planning, defining, managing, and marketing components of product-line administration afford responsiveness to the current situation and the development of quality products that will ensure that medical record departments are prepared for the future.

  17. The Impact of On-line Searching on Document Supply Services at Individual Libraries

    NASA Astrophysics Data System (ADS)

    Hosono, Kimio; Tanaka, Isao; Fukazawa, Yoshiko

    As use of on-line searching services has progressed in libraries, requests on primary materials have increased much more than before. For the purpose of clarifying this trend and countermeasures against it a survey by questionnaire was conducted in 1985. The respondants from totally 112 libraries are as follows ; 60 industrial libraries, 41 academic libraries and 11 libraries of research institutes and laboratories. It was shown that industrial libraries have received more requests on primary materials mostly resulting from on-line searching while the requests have not increased remarkably in academic libraries. Regardless the type of libraries, almost all libraries can not fully meet the requests with their own collection so that industrial libraries have to rely on external information services and academic libraries utilize interlibrary loan system. Requests are sent via on-line from industrial libraries, and by mail from academic libraries. In fact, any-libraries are not likely to review their material-collecting policy. Therefore it is urgent to establish the system which enables use of external information services or interlibrary loan system more than ever.

  18. Radiolucent lines below the tibial component of a total knee replacement (TKR) – a comparison between single-and two-stage cementation techniques

    PubMed Central

    Debnath, Ujjwal Kanti; Graham, Niall McKenzie

    2007-01-01

    Early non-progressive horizontal radiolucent lines (RLLs) (<2 mm) under the tibial component following cemented total knee replacement (TKR) are considered to result from poor cement injection into cancellous bone. These RLLs may facilitate the entry of joint fluid and wear debris into the interface, which may proceed to ballooning osteolysis. There is currently no consensus on the preferred cementing technique (single- versus two-stage cementation) in TKR. We have prospectively analysed postoperative radiographs in 50 consecutive TKRs to compare the RLLs following single- (25 TKRs) and two-stage (25 TKRs) cementation techniques. Of the TKR radiographs studied, 26 (52%) had RLLs; nine (36%) of these were single-stage TKRs, and 17 (68%) were two-stage TKRs. This study demonstrates that single-stage cementing may be superior to the two-stage technique in terms of avoiding RLLs in immediate postoperative TKRs. PMID:17364179

  19. Toxicogenomic Screening of Replacements for Di(2-Ethylhexyl) Phthalate (DEHP) Using the Immortalized TM4 Sertoli Cell Line

    PubMed Central

    Nardelli, Thomas C.; Erythropel, Hanno C.; Robaire, Bernard

    2015-01-01

    Phthalate plasticizers such as di(2-ethylhexyl) phthalate (DEHP) are being phased out of many consumer products because of their endocrine disrupting properties and their ubiquitous presence in the environment. The concerns raised from the use of phthalates have prompted consumers, government, and industry to find alternative plasticizers that are safe, biodegradable, and have the versatility for multiple commercial applications. We examined the toxicogenomic profile of mono(2-ethylhexyl) phthalate (MEHP, the active metabolite of DEHP), the commercial plasticizer diisononyl cyclohexane-1,2-dicarboxylate (DINCH), and three recently proposed plasticizers: 1,4-butanediol dibenzoate (BDB), dioctyl succinate (DOS), and dioctyl maleate (DOM), using the immortalized TM4 Sertoli cell line. Results of gene expression studies revealed that DOS and BDB clustered with control samples while MEHP, DINCH and DOM were distributed far away from the control-DOS-BDB cluster, as determined by principle component analysis. While no significant changes in gene expression were found after treatment with BDB and DOS, treatment with MEHP, DINCH and DOM resulted in many differentially expressed genes. MEHP upregulated genes downstream of PPAR and targeted pathways of cholesterol biosynthesis without modulating the expression of PPAR’s themselves. DOM upregulated genes involved in glutathione stress response, DNA repair, and cholesterol biosynthesis. Treatment with DINCH resulted in altered expression of a large number of genes involved in major signal transduction pathways including ERK/MAPK and Rho signalling. These data suggest DOS and BDB may be safer alternatives to DEHP/MEHP than DOM or the commercial alternative DINCH. PMID:26445464

  20. MDCA Needle 1 Replacement

    NASA Image and Video Library

    2013-04-22

    ISS035-E-025557(22 April 2013) ---Multi-user Droplet Combustion Apparatus (MDCA) Hardware Replacement: Cassidy accessed the Combustion Integration Rack (CIR) Combustion Chamber and removed the MDCA Chamber Insert Assembly (CIA). He then replaced the MDCA Needle 1 due to a fuel line that was damaged during previous activities when the MDCA CIA was being removed from the Combustion Chamber.

  1. A trenchless alternative for gas main replacement

    SciTech Connect

    Schuler, D.; Dierker, K.; Robinson, J.

    1997-06-01

    Pipe-bursting is a trenchless pipeline replacement method that has primarily been used in the wastewater industry to replace deteriorating sewers. Originally, however, this technology was brought to the US in the mid-1980s as a method for the replacement of gas mains. The process is now being rediscovered by gas utilities for use in specific situations as a means of distribution system renewal. Cinergy Corp. has a program of examining and testing new gas main installation and rehabilitation methods under actual field conditions. As part of these efforts, Union Light Heat and Power Co., a division of Cinergy serving the Covington, KY area, recently used pipe-bursting technology to replace a 400-foot section of 8-inch diameter cast iron main. The new line was then put into service as an additional feeder to customers in the Covington service area. Cinergy engineers have determined that to be considered for pipe-bursting, a main should be the end of a one-way feed or in a two-way feed where there is a sufficient amount of gas to supply customers on other parts of the line. In most cases, the company does not shut off customer service for more than one day`s work, otherwise a bypass system may be required. Another prime consideration is the number of customer service connections on a line. This is a factor because of the need to excavate and access service connections along the newly installed line. A third requirement for pipe-bursting is the need to have at least three feet of ground cover over the main. The installation procedure is described.

  2. The effect of individual counseling, line follow-up, and free nicotine replacement therapy on smoking cessation in the samples of Iranian smokers: Examination of transtheoretical model

    PubMed Central

    Sharifirad, Gholam Reza; Eslami, Ahmad Ali; Charkazi, Abdurrahman; Mostafavi, Firozeh; Shahnazi, Hossein

    2012-01-01

    Background: According to transtheoretical model (TTM), Stage matched interventions are more effective in quitting. The objective of current study was to investigate the effect of individual counseling, line follow-up, and free nicotine replacement therapy (NRT) on smoking cessation in smokers who are in preparation stage of smoking. Materials and Methods: In a randomized clinical trial design, through sending the short message system, potential participants in preparation stage of smoking were recruited and divided into control (n = 60)and treatment (n = 50) groups. The treatment group received an in-person counseling, line follow-up, and free NRT. TTM variables trend; pros and cons of smoking, behavioral and experiential processes, temptation, were assessed at baseline, 3 and 6 months follow-up along with point prevalence and continuous abstinence. Results: Continuous abstinence at 6-month follow-up were 3.3% (n = 2) in control group and 46% (n = 23) in the treatment group (x2 = 34.041, P < 0.001). Time Χ group analyses indicated that except cons of smoking (P > 0.05), all TTM constructs had significantly changed; temptation (F = 36.864, P < 0.001), pros (F = 12.172, P < 0.001), experiential processes (F = 3.377, P < 0.001), and behavioral processes (F = 11.131, P < 0.001). Conclusion: Interventions based on TTM variables increased the quite rate in prepared and motivated people. Our findings suggest that interventions through individual counseling along with free NRT and line follow-up in people who prepare for quitting are beneficial for our country. PMID:23853630

  3. Knee joint replacement - slideshow

    MedlinePlus

    ... presentations/100088.htm Knee joint replacement - series—Normal anatomy To use the sharing features on this page, ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

  4. Using a Plan-Do-Study-Act cycle to introduce a new or service line.

    PubMed

    Nakayama, Don K; Bushey, Timothy N; Hubbard, Irene; Cole, Dawn; Brown, Amanda; Grant, Timothy M; Shaker, Issam J

    2010-09-01

    In 2008, a multidisciplinary team at the Medical Center of Georgia, Macon, began a one-year Plan-Do-Study-Act (PDSA) cycle to implement a high-quality pediatric surgery service line. The PDSA team defined goals, objectives, and measurable performance metrics and then reviewed cases and aggregated data monthly to identify and improve clinical, process, instrument, and supply problems as well as patient transfer issues. The PDSA cycle led to improvements in team performance, communication, and patient transfer and decreased the number of problems associated with instruments, supplies, equipment, and surgeon tardiness. Copyright 2010 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  5. Replacement of Imu-Cmu intron by NeoR gene alters Imu germ-line expression but has no effect on V(D)J recombination.

    PubMed

    Haddad, Dania; Dougier, Hei-Lanne; Laviolette, Nathalie; Puget, Nadine; Khamlichi, Ahmed Amine

    2010-02-01

    The NeoR gene has often been used to unravel the mechanisms underlying long-range interactions between promoters and enhancers during V(D)J assembly and class switch recombination (CSR) in the immunoglobulin heavy chain (IgH) locus. This approach led to the notion that CSR is regulated through competition of germ-line (GL) promoters for activities displayed by the 3' regulatory region (3'RR). This polarized long-range effect of the 3'RR is disturbed upon insertion of NeoR gene in the IgH constant (C(H)) region, where only GL transcription derived from upstream GL promoters is impaired. In the context of V(D)J recombination, replacement of Emu enhancer or Emu core enhancer (cEmu) by NeoR gene fully blocked V(D)J recombination and mu0 GL transcription which originates 5' of DQ52 and severely diminished Imu GL transcription derived from Emu/Imu promoter, suggesting a critical role for cEmu in the regulation of V(D)J recombination and of mu0 and Imu expression. Here we focus on the effect of NeoR gene on mu0 and Imu GL transcription in a mouse line in which the Imu-Cmu intron was replaced by a NeoR gene in the sense-orientation. B cell development was characterized by a marked but incomplete block at the pro-B cell stage. However, V(D)J recombination was unaffected in sorted pro-B and pre-B cells excluding an interference with the accessibility control function of Emu. mu0 GL transcription initiation was relatively normal but the maturation step seemed to be affected most likely through premature termination at NeoR polyadenylation sites. In contrast, Imu transcription initiation was impaired suggesting an interference of NeoR gene with the IgH enhancers that control Imu expression. Surprisingly, in stark contrast with the NeoR effect in the C(H) region, LPS-induced NeoR expression restored Imu transcript levels to normal. The data suggest that Emu enhancer may be the master control element that counteracts the down-regulatory "Neo effect" on Imu expression upon LPS

  6. [Mental health as a front-line service for bewildered persons].

    PubMed

    Mulder, C L; van Weeghel, J; Wierdsma, A; Zoeteman, J; Schene, A

    'Bewildered persons' have often been in the news over the last few years. There has been much discussion about the meaning of the term 'bewildered persons', the number of people involved, the way the problem should be tackled and the role of the mental health services.
    AIM: To look critically at the term 'bewildered persons' and to discuss the suspected increase in numbers and the role of mental health services.
    METHOD: Review and discussion of the relevant literature relating to 'bewildered persons' which has been published in the last 25 years.
    RESULTS: The term 'bewildered persons' is a general label given by the Dutch police to several groups of people. Suicide rates are rising and more and more people are being compulsorily admitted to psychiatric clinics and hospitals. These factors indicate that increasing numbers of people may now be a danger to themselves and to their fellow-citizens. It is not clear whether the increase in numbers is real or simply reflects the extra attention given by the police. These people may in fact be a new group consisting of persons already known to the mental health services. A national team that aims to improve the care of 'bewildered persons' has made several recommendations to stop the increase: prevention and better cooperation between municipalities and mental health facilities. In our view the mental health services should operate at the front-line of the public mental health service, providing low-threshold diagnostics, assertive outreach and treatment for patients who have mental disorders but are unwilling to accept care or treatment. Such a service requires adequate finance, good cooperative agreements and removal of the bureaucratic and financial barriers that prevent patients from seeking care.
    CONCLUSION: 'Bewildered persons' is an umbrella term used to denote people who urgently require care and are a public nuisance and who display disturbing behavior. 'Bewildered persons', who now form a part

  7. Current and proposed molecular diagnostics in a genitourinary service line laboratory at a tertiary clinical institution.

    PubMed

    Udager, Aaron M; Alva, Ajjai; Mehra, Rohit

    2014-01-01

    The idea that detailed knowledge of molecular oncogenesis will drive diagnostic, prognostic, and therapeutic clinical decision making in an increasingly multidisciplinary practice of oncologic care has been anticipated for many years. With the recent rapid advancement in our understanding of the molecular underpinnings of genitourinary malignancies, this concept is now starting to take shape in the fields of prostate, kidney, bladder, testicular, and penile cancer. Such breakthroughs necessitate the development of robust clinical-grade assays that can be quickly made available for patients to facilitate diagnosis in challenging cases, risk-stratify patients for subsequent clinical management, select the appropriate targeted therapy from among increasingly diverse and numerous options, and enroll patients in advanced clinical trials. This rapid translation of basic and clinical cancer research requires a streamlined, multidisciplinary approach to clinical assay development, termed here the molecular diagnostics service line laboratory. In this review, we summarize the current state and explore the future of molecular diagnostics in genitourinary oncology to conceptualize a genitourinary service line laboratory at a tertiary clinical institution.

  8. Experiences concerning the service life of rubber linings applied in flue gas desulfurization plants

    SciTech Connect

    Berger, W.

    1999-11-01

    Since the beginning of the eighties scrubbers and other components in European FGD plants have been protected against corrosion using rubber lining. Extensive experience is available based on service lives of rubber lining of more than 15 years. The paper will consider the various rubber types and curing systems used. While the USA and Japan had already begun retrofitting their existing coal-fired power stations with flue gas desulfurization (FGD) plants in the seventies, Germany followed suit in the eighties as a result of the decree issued for large-scale firing plants. Concurrent with this development retrofitting has also been enhanced in other European countries like Austria and the Netherlands, later followed by Denmark, Finland and England. After the collapse of the Eastern Bloc retrofitting work has been implemented in Eastern Germany, Poland, the Czech Republic and Slovakia. Today FGD plants are being put into operation in Spain, Italy, Turkey and Greece or are on the verge of being put into service. More than 150 plants of this kind are operated by using the wet-scrubbing process with limestone or calcium hydroxide suspensions.

  9. Developing Effective Continuous On-Line Monitoring Technologies to Manage Service Degradation of Nuclear Power Plants

    SciTech Connect

    Meyer, Ryan M.; Ramuhalli, Pradeep; Bond, Leonard J.; Cumblidge, Stephen E.

    2011-09-30

    Recently, there has been increased interest in using prognostics (i.e, remaining useful life (RUL) prediction) for managing and mitigating aging effects in service-degraded passive nuclear power reactor components. A vital part of this philosophy is the development of tools for detecting and monitoring service-induced degradation. Experience with in-service degradation has shown that rapidly-growing cracks, including several varieties of stress corrosion cracks (SCCs), can grow through a pipe in less than one fuel outage cycle after they initiate. Periodic inspection has limited effectiveness at detecting and managing such degradation requiring a more versatile monitoring philosophy. Acoustic emission testing (AET) and guided wave ultrasonic testing (GUT) are related technologies with potential for on-line monitoring applications. However, harsh operating conditions within NPPs inhibit the widespread implementation of both technologies. For AET, another hurdle is the attenuation of passive degradation signals as they travel though large components, relegating AET to targeted applications. GUT is further hindered by the complexity of GUT signatures limiting its application to the inspection of simple components. The development of sensors that are robust and inexpensive is key to expanding the use of AET and GUT for degradation monitoring in NPPs and improving overall effectiveness. Meanwhile, the effectiveness of AET and GUT in NPPs can be enhanced through thoughtful application of tandem AET-GUT techniques.

  10. Ankle replacement

    MedlinePlus

    ... is surgery to replace the damaged bone and cartilage in the ankle joint. Artificial joint parts (prosthetics) ... Your surgeon will remove the damaged bone and cartilage. Your surgeon will replace the damaged part of: ...

  11. Hip Replacement

    MedlinePlus

    ... replacement is an operation in which a damaged hip joint is removed and replaced with an artificial joint. ... are many medical conditions that can damage the hip joint. (Watch the video to learn about what goes ...

  12. The Effects of Postdischarge Telephone Counseling and Short Message Service on the Knee Function, Activities of Daily Living, and Life Satisfaction of Patients Undergoing Total Knee Replacement.

    PubMed

    Park, Kyung Hye; Song, Mi Ryeong

    No study comparing short message service (SMS) texts and telephone counseling for patients undergoing total knee replacement (TKR) has been reported. The purpose of the study was to provide postdischarge telephone counseling and SMS texts to TKR patients and to analyze the effects of these services on their knee function (KF), activities of daily living (ADL), and life satisfaction (LS). This study used a randomized clinical trial design. This study was conducted with 40 patients (counseling group: 21; SMS group: 19). In the telephone counseling group and the SMS group, KF, ADL, and LS were assessed before surgery and 1 and 3 months after TKR. Telephone counseling and SMS texts have the same effects on KF, ADL, and LS of TKR patients. Future research is needed to determine optimal frequency and duration of post-TKR SMS to support patients who have undergone TKR.

  13. Lines

    ERIC Educational Resources Information Center

    Mires, Peter B.

    2006-01-01

    National Geography Standards for the middle school years generally stress the teaching of latitude and longitude. There are many creative ways to explain the great grid that encircles our planet, but the author has found that students in his college-level geography courses especially enjoy human-interest stories associated with lines of latitude…

  14. Lines

    ERIC Educational Resources Information Center

    Mires, Peter B.

    2006-01-01

    National Geography Standards for the middle school years generally stress the teaching of latitude and longitude. There are many creative ways to explain the great grid that encircles our planet, but the author has found that students in his college-level geography courses especially enjoy human-interest stories associated with lines of latitude…

  15. A new service at the starting line - Direct broadcasting from satellites

    NASA Astrophysics Data System (ADS)

    Siocos, C. A.

    Aspects of the development of direct broadcast TV satellite systems (DBS) are reviewed, noting deficiencies, peculiarities, benefits, and regulatory considerations. The U.S. ended experimentation in DBS technology with the ATS-6 satellite, while other governments, such as Japan, Canada, and Australia continued tests. Russia orbited the Ekran DBS satellite for 714 MHz transmission to Siberian receivers in 1976. DBS can transmit to either community or individual antennas, and the ITU has decided that the international rules established for DBS systems shall permit any country wishing to introduce its own satellite be assured an orbit and frequencies for operations. The DBS systems may replace national broadcasting arrays, although twice a year, at equinox, DBS satellites will experience eclipse conditions which will require battery systems or temporary suspension of services. Problems such as spillover of a signal from one country to another are regarded as tolerable so long as it cannot be avoided, but signals pirated by unauthorized receivers will pose difficulties for operators of pay-television equipment.

  16. 76 FR 47593 - Award of Replacement Grant for Preventive Health to Lutheran Social Services of North Dakota...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... to Lutheran Social Services of North Dakota, Fargo, ND AGENCY: Office of Refugee Resettlement, ACF... for medical screening and initial medical treatment for refugees. Amount of Award: $66,000. SUMMARY... arriving refugees have access to preventive health screenings, the Administration for Children and...

  17. Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects

    PubMed Central

    Chang, Jer-Cherng

    2017-01-01

    Mutations in TDP-43 are associated with proteinaceous inclusions in neurons and are believed to be causative in neurodegenerative diseases such as frontotemporal dementia or amyotrophic lateral sclerosis. Here we describe a Drosophila system where we have engineered the genome to replace the endogenous TDP-43 orthologue with wild type or mutant human TDP-43(hTDP-43). In contrast to other models, these flies express both mutant and wild type hTDP-43 at similar levels to those of the endogenous gene and importantly, no age-related TDP-43 accumulation observed among all the transgenic fly lines. Immunoprecipitation of TDP-43 showed that flies with hTDP-43 mutations had increased levels of ubiquitination and phosphorylation of the hTDP-43 protein. Furthermore, histologically, flies expressing hTDP-43 M337V showed global, robust neuronal staining for phospho-TDP. All three lines: wild type hTDP-43, -G294A and -M337V were homozygous viable, with no defects in development, life span or behaviors observed. The primary behavioral defect was that flies expressing either hTDP-43 G294A or M337V showed a faster decline with age in negative geotaxis. Together, these observations implied that neurons could handle these TDP-43 mutations by phosphorylation- and ubiquitin-dependent proteasome systems, even in a background without the wild type TDP-43. Our findings suggest that these two specific TDP-43 mutations are not inherently toxic, but may require additional environmental or genetic factors to affect longevity or survival. PMID:28686708

  18. Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.

    PubMed

    Chang, Jer-Cherng; Morton, David B

    2017-01-01

    Mutations in TDP-43 are associated with proteinaceous inclusions in neurons and are believed to be causative in neurodegenerative diseases such as frontotemporal dementia or amyotrophic lateral sclerosis. Here we describe a Drosophila system where we have engineered the genome to replace the endogenous TDP-43 orthologue with wild type or mutant human TDP-43(hTDP-43). In contrast to other models, these flies express both mutant and wild type hTDP-43 at similar levels to those of the endogenous gene and importantly, no age-related TDP-43 accumulation observed among all the transgenic fly lines. Immunoprecipitation of TDP-43 showed that flies with hTDP-43 mutations had increased levels of ubiquitination and phosphorylation of the hTDP-43 protein. Furthermore, histologically, flies expressing hTDP-43 M337V showed global, robust neuronal staining for phospho-TDP. All three lines: wild type hTDP-43, -G294A and -M337V were homozygous viable, with no defects in development, life span or behaviors observed. The primary behavioral defect was that flies expressing either hTDP-43 G294A or M337V showed a faster decline with age in negative geotaxis. Together, these observations implied that neurons could handle these TDP-43 mutations by phosphorylation- and ubiquitin-dependent proteasome systems, even in a background without the wild type TDP-43. Our findings suggest that these two specific TDP-43 mutations are not inherently toxic, but may require additional environmental or genetic factors to affect longevity or survival.

  19. A dismantling study of assertive outreach services: comparing activity and outcomes following replacement with the FACT model.

    PubMed

    Firn, Mike; Hindhaugh, Keelyjo; Hubbeling, Dieneke; Davies, Gwyn; Jones, Ben; White, Sarah Jane

    2013-06-01

    Financial constraints and some disappointing research evaluations have seen English assertive outreach (AO) teams subject to remodelling, decommissioning and integration into standard care. We tested a specific alternative model of integrating the AO function from two AO teams into six standard community mental health teams (CMHT). The Flexible Assertive Community Treatment model (FACT) was adopted from the Netherlands (Van Veldhuizen, Commun Mental Health J 43(4):421-433, 2007; Bond and Drake, Commun Mental Health J 43(4):435-438, 2007). We aimed to demonstrate non-inferiority in clinical effectiveness and thereby show cost efficiencies associated with FACT. Outcomes were compared in a mirror-image study of the 12 months periods pre- and post-service change with eligible individuals from the AO teams' caseloads (n = 112) acting as their own controls. We also conducted a cost-consequence analysis of the changes. Outcome data regarding admissions, use of crisis and home treatment, frequency of contact and DNA rate were extracted from the electronic patient record. The results show AO patients (n = 112) transferred to standard CMHTs with FACT had significantly fewer admissions and a halving of bed use (21 fewer admission and 2,394 fewer occupied bed days) whilst being in receipt of a less intensive service (2,979 fewer contacts). This was offset by significantly poorer engagement but not by increased use of crisis and home treatment services. Enhancing multi-disciplinary CMHTs with FACT provides a clinically effective alternative to AO teams. FACT offers a cost-effective model compared to AO.

  20. Replacing monocultures with mixed-species stands: Ecosystem service implications of two production forest alternatives in Sweden.

    PubMed

    Felton, Adam; Nilsson, Urban; Sonesson, Johan; Felton, Annika M; Roberge, Jean-Michel; Ranius, Thomas; Ahlström, Martin; Bergh, Johan; Björkman, Christer; Boberg, Johanna; Drössler, Lars; Fahlvik, Nils; Gong, Peichen; Holmström, Emma; Keskitalo, E Carina H; Klapwijk, Maartje J; Laudon, Hjalmar; Lundmark, Tomas; Niklasson, Mats; Nordin, Annika; Pettersson, Maria; Stenlid, Jan; Sténs, Anna; Wallertz, Kristina

    2016-02-01

    Whereas there is evidence that mixed-species approaches to production forestry in general can provide positive outcomes relative to monocultures, it is less clear to what extent multiple benefits can be derived from specific mixed-species alternatives. To provide such insights requires evaluations of an encompassing suite of ecosystem services, biodiversity, and forest management considerations provided by specific mixtures and monocultures within a region. Here, we conduct such an assessment in Sweden by contrasting even-aged Norway spruce (Picea abies)-dominated stands, with mixed-species stands of spruce and birch (Betula pendula or B. pubescens), or spruce and Scots pine (Pinus sylvestris). By synthesizing the available evidence, we identify positive outcomes from mixtures including increased biodiversity, water quality, esthetic and recreational values, as well as reduced stand vulnerability to pest and pathogen damage. However, some uncertainties and risks were projected to increase, highlighting the importance of conducting comprehensive interdisciplinary evaluations when assessing the pros and cons of mixtures.

  1. Glial cell-line derived neurotrophic factor (GDNF) replacement attenuates motor impairments and nigrostriatal dopamine deficits in 12-month-old mice with a partial deletion of GDNF

    PubMed Central

    Littrell, Ofelia M.; Granholm, Ann-Charlotte; Gerhardt, Greg A.; Boger, Heather A.

    2013-01-01

    Glial cell-line derived neurotrophic factor (GDNF) has been established as a growth factor for the survival and maintenance of dopamine (DA) neurons. In phase I clinical trials, GDNF treatment in Parkinson’s disease patients led to improved motor function and GDNF has been found to be down regulated in Parkinson’s disease patients. Studies using GDNF heterozygous (Gdnf+/−) mice have demonstrated that a partial reduction of GDNF leads to an age-related accelerated decline in nigrostriatal DA system- and motor-function and increased neuro-inflammation and oxidative stress in the substantia nigra (SN). Therefore, the purpose of the current studies was to determine if GDNF replacement restores motor function and functional markers within the nigrostriatal DA system in middle-aged Gdnf+/− mice. At 11 months of age, male Gdnf+/− and wildtype (WT) mice underwent bilateral intra-striatal injections of GDNF (10 μg) or vehicle. Locomotor activity was assessed weekly 1–4 weeks after treatment. Four weeks after treatment, their brains were processed for analysis of GDNF levels and various DAergic and oxidative stress markers. An intrastriatal injection of GDNF increased motor activity in Gdnf+/− mice to levels comparable to WT mice (1 week after injection) and this effect was maintained through the 4-week time point. This increase in locomotion was accompanied by a 40% increase in striatal GDNF protein levels and SN GDNF expression in Gdnf+/− mice. Additionally, GDNF treatment significantly increased the number of tyrosine hydroxylase (TH)-positive neurons in the SN of middle-aged Gdnf+/− mice, but not WT mice, which was coupled with reduced oxidative stress in the SN. These studies further support that long-term changes related to the dysfunction of the nigrostriatal pathway are influenced by GDNF expression and add that this dysfunction appears to be responsive to GDNF treatment. Additionally, these studies suggest that long-term GDNF depletion alters the

  2. Accessing On-Line Services with Synthetic Speech: America Online, CompuServe, and Internet Service Providers.

    ERIC Educational Resources Information Center

    Earl, Crista L.; Leventhal, Jay D.

    1998-01-01

    This product evaluation reviews two of the most popular online Internet service providers, America Online and CompuServe, and describes their advantages and disadvantages for synthetic speech-users compared to services that offer Internet access only, such as Concentric or Netcome. It concludes that CompuServe is a better choice for individuals…

  3. Low Contribution of PbO2-Coated Lead Service Lines to Water Lead Contamination at the Tap

    EPA Science Inventory

    To determine if field experience corroborates that formation of stable PbO2 coatings on lead service lines (LSLs) provides an effective lead contamination control strategy, lead profile sampling was undertaken at eight home kitchen taps in three US cities (Newport, Rhode Island; ...

  4. Pre-Service Middle School Mathematics Teachers' Understanding of Students' Knowledge: Location of Decimal Numbers on a Number Line

    ERIC Educational Resources Information Center

    Girit, Dilek; Akyuz, Didem

    2016-01-01

    Studies reveal that students as well as teachers have difficulties in understanding and learning of decimals. The purpose of this study is to investigate students' as well as pre-service teachers' solution strategies when solving a question that involves an estimation task for the value of a decimal number on the number line. We also examined the…

  5. Low Contribution of PbO2-Coated Lead Service Lines to Water Lead Contamination at the Tap

    EPA Science Inventory

    To determine if field experience corroborates that formation of stable PbO2 coatings on lead service lines (LSLs) provides an effective lead contamination control strategy, lead profile sampling was undertaken at eight home kitchen taps in three US cities (Newport, Rhode Island; ...

  6. Shoulder replacement

    MedlinePlus

    ... the opening at the end of the shoulder blade, called the socket. This type of joint allows ... head. The socket part (glenoid) of your shoulder blade will be replaced with a smooth plastic shell ( ...

  7. FEDIX on-line information service: Design, develop, test, and implement, an on-line research and education information service. Annual status report, March 1, 1991--February 29, 1992

    SciTech Connect

    Rodman, J.A.

    1992-06-01

    The FEDIX Annual Status Report provides details regarding an on-line information project designed, developed and implemented by Federal Information Exchange, Inc., a diversified information services company. This document details the project design activities, summarizes the developmental phases of the project and describes the implementation activities generated to fulfill the project`s objectives. The information contained in this document illustrates FIE`s continuing commitment to serve as the link that facilitates the dissemination of federal information to the education community. This report reviews the project accomplishments and describes intended service enhancements.

  8. Esophageal replacement.

    PubMed

    Kunisaki, Shaun M; Coran, Arnold G

    2017-04-01

    This article focuses on esophageal replacement as a surgical option for pediatric patients with end-stage esophageal disease. While it is obvious that the patient׳s own esophagus is the best esophagus, persisting with attempts to retain a native esophagus with no function and at all costs are futile and usually detrimental to the overall well-being of the child. In such cases, the esophagus should be abandoned, and the appropriate esophageal replacement is chosen for definitive reconstruction. We review the various types of conduits used for esophageal replacement and discuss the unique advantages and disadvantages that are relevant for clinical decision-making. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. 76 FR 32323 - Limited Service Domestic Voyage Load Lines for River Barges on Lake Michigan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-06

    ... established in the final rule published on November 18, 2010. Specifically, the weather restrictions based on Small Craft Advisory conditions are being replaced with the original weather restrictions implemented in...) conditions as the limiting weather restrictions in place of a variety of weather conditions used under the...

  10. Creating and Maintaining a Successful Service Line in an Academic Medical Center at the Dawn of Value-Based Care: Lessons Learned From the Heart and Vascular Service Line at UMass Memorial Health Care.

    PubMed

    Phillips, Robert A; Cyr, Jay; Keaney, John F; Messina, Louis M; Meyer, Theo E; Tam, Stanley K C; Korenda, Kathleen; Darrigo, Melinda; Kumar, Pooja; Challapalli, Sailu

    2015-10-01

    The service line (SL) model has been proven to help shift health care toward value-based services, which is characterized by coordinated, multidisciplinary, high-quality, and cost-effective care. However, academic medical centers struggle with how to effectively set up SL structures that overcome the organizational and cultural challenges associated with simultaneously delivering the highest-value care for the patient and advancing the academic mission. In this article, the authors examine the evolution of UMass Memorial Health Care's heart and vascular service line (HVSL) from 2006 to 2011 and describe the impact on its success of multiple strategic decisions. These include key academic physician leadership recruitments and engagement via a matrixed governance and management model; development of multidisciplinary teams; empowerment of SL leadership through direct accountability and authority over programs and budgets; joint educational and training programs; incentives for academic achievement; and co-localization of faculty, personnel, and facilities. The authors also explore the barriers to success, including the need to overcome historical departmental-based silos, cultural and training differences among disciplines, confusion engendered by a matrixed reporting structure, and faculty's unfamiliarity with the financial and organizational skills required to operate a successful SL. Also described here is the impact that successful implementation of the SL has on creating high-quality services, increased profitability, and contribution to the financial stability and academic achievement of the academic medical center.

  11. Are you ready for your first European?. [on-line database connection to foreign services

    NASA Technical Reports Server (NTRS)

    Jack, Robert F.

    1986-01-01

    Ways in which American online searchers can avail themselves of foreign services are discussed. It is noted that many European services offer the user an option in the choice of command protocols. Reasons why Americans generally do not use European online services include the fact that foreign databases tend to contain citations to foreign documents and many Americans do not read and speak any language other than English.

  12. Are you ready for your first European?. [on-line database connection to foreign services

    NASA Technical Reports Server (NTRS)

    Jack, Robert F.

    1986-01-01

    Ways in which American online searchers can avail themselves of foreign services are discussed. It is noted that many European services offer the user an option in the choice of command protocols. Reasons why Americans generally do not use European online services include the fact that foreign databases tend to contain citations to foreign documents and many Americans do not read and speak any language other than English.

  13. The Business Information Services: Old-Line Online Moves to the Web.

    ERIC Educational Resources Information Center

    O'Leary, Mick

    1997-01-01

    Although the availability of free information on the World Wide Web has placed traditional, fee-based proprietary online services on the defensive, most major online business services are now on the Web. Highlights several business information providers: Profound, NewsNet and ProQuest Direct, Dow Jones and Wall Street Journal Interactive Edition,…

  14. A Hot-Line Emergency Service for the Ambulatory Frail Elderly.

    ERIC Educational Resources Information Center

    Wolf-Klein, Gisele P.; Silverstone, Felix A.

    1987-01-01

    Surveyed patients and families who used hotline emergency service in ambulatory day treatment center for frail elderly. Results revealed appropriate use of service: Most calls required medical intervention, including hospitalization in 31 percent of cases. Findings suggest that 24-hour medical coverage is necessary and cost efficient. (Author/NB)

  15. The Business Information Services: Old-Line Online Moves to the Web.

    ERIC Educational Resources Information Center

    O'Leary, Mick

    1997-01-01

    Although the availability of free information on the World Wide Web has placed traditional, fee-based proprietary online services on the defensive, most major online business services are now on the Web. Highlights several business information providers: Profound, NewsNet and ProQuest Direct, Dow Jones and Wall Street Journal Interactive Edition,…

  16. Knowledge of and Opinions on HIV Preexposure Prophylaxis Among Front-Line Service Providers at Canadian AIDS Service Organizations

    PubMed Central

    Senn, Heather; Wilton, James; Sharma, Malika; Fowler, Shawn

    2013-01-01

    Abstract Oral daily tenofovir/emtricitabine (Truvada) is approved in the United States for HIV preexposure prophylaxis (PrEP) but has generated controversy in the media and within HIV-affected communities. We conducted an online survey about PrEP-related knowledge, experience, opinions, and learning needs, and received 160 responses from service providers at Canadian AIDS Service Organizations. Respondents were cautiously optimistic about PrEP and 48.8% believed that PrEP warranted Health Canada approval. In multivariable logistic regression, support for PrEP approval was associated with more years working in HIV (odds ratio=1.89 per decade, 95% CI=1.10, 3.25), low baseline familiarity with PrEP (OR=3.24, 95% CI=1.01, 14.41), and knowing someone who had used PrEP (OR=4.39, 95% CI=1.28,15.08). Participants major concerns about PrEP were similar to those highlighted in other publications, and some issues specific to certain target populations were raised. Several participants (26.2%) had been asked about PrEP in the past year and 10.6% knew of one or more Canadian who had used PrEP. Despite clients' interest, most participants thought that they (60.6%) or their organization (63.1%) did not have enough current knowledge about PrEP, highlighting the need for further education on this novel HIV prevention strategy. PMID:23731254

  17. Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.

    PubMed

    Rodríguez-Acebes, Sara; de la Cueva, Paloma; Fernández-Hernando, Carlos; Ferruelo, Antonio J; Lasunción, Miguel A; Rawson, Robert B; Martínez-Botas, Javier; Gómez-Coronado, Diego

    2009-05-13

    Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol, a defect resulting from the absence of mRNA for sterol-Delta24-reductase. Using J774 cells, we addressed the capacity of desmosterol to replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway. J774 cells were able to grow indefinitely after the virtually total replacement of cholesterol by desmosterol (J774-D cells). Inhibition of sterol biosynthesis with lovastatin suppressed J774-D cell proliferation. Desmosterol prevented this effect, but its analogue, cholest-5,22-trans-dien-3beta-ol, did not. Addition of desmosterol inhibited processing of SREBP-1 and -2 and also reduced the expression of SREBP-targeted genes. As occurs in cholesterol-containing cells, 25-hydroxycholesterol was more potent than desmosterol or cholesterol in suppressing these processes. Moreover, desmosterol addition enhanced the expression of Abca1 and Srebf1c, two LXR (liver X receptor)-targeted genes. To test the ability of endogenously produced desmosterol to regulate gene expression, J774-D cells were pretreated with lovastatin to inhibit sterol biosynthesis. After removal of the inhibitor the expression of SREBP-targeted genes decreased and that of an LXR-targeted gene increased, reaching control levels. Our results demonstrate that the virtually complete replacement of cholesterol by desmosterol is compatible with cell growth and the functioning of the SREBP pathway. In these cells, desmosterol suppresses SREBP processing and targeted gene expression, and it is especially effective activating LXR-targeted genes.

  18. Detection and Evaluation of Elevated Lead Release from Service Lines: A Field Study

    EPA Science Inventory

    Comparative stagnation sampling conducted in 32 homes in Chicago, Illinois with lead service (LSLs) demonstrated that the existing regulatory sampling protocol under the U. S. Lead and Copper Rule (LCR) systematically underestimated lead corrosion. Lead levels were highest within...

  19. Detection and Evaluation of Elevated Lead Release from Service Lines: A Field Study

    EPA Science Inventory

    Comparative stagnation sampling conducted in 32 homes in Chicago, Illinois with lead service (LSLs) demonstrated that the existing regulatory sampling protocol under the U. S. Lead and Copper Rule (LCR) systematically underestimated lead corrosion. Lead levels were highest within...

  20. Line officers' views on stated USDA Forest Service values and the agency reward system.

    Treesearch

    James J. Kennedy; Richard W. Haynes; Xiaoping. Zhou

    2005-01-01

    To update and expand a study done in 1989 (Kennedy et al. 1992), we surveyed line officers attending the third National Forest Supervisors’ Conference (Chief, Associate Chief, deputy chiefs, regional foresters, directors of International Institute of Tropical Forestry and State and Private Forestry Northeastern Area, and forest supervisors; January 2004) and a 40-...

  1. In the Shadows: Non-Tenure-Line Instructors in Pre-Service Teacher Education

    ERIC Educational Resources Information Center

    Kosnik, Clare; Beck, Clive

    2008-01-01

    This article looks at the non-tenure-line instructors in a teacher education programme. Although they play a crucial role in teacher education, they largely toil in the shadows. They have limited voice in programme decisions, are offered little or no induction, and often work in isolation. The high turnover in staff and their heavy teaching and…

  2. Provider-Line Ancillary Service Support: A Study of Performance and Cost Data

    DTIC Science & Technology

    1992-07-01

    military 21040 37 12592 760 Partner 4 68 0 0 Allergy military 846 0 1285 214 Partner 265 0 5155 0 Dermatology military 750 3051 2478 16 Partner 12 48 470 0... Allergy military 4081.0 0 1285 1212 Partner 469.7 0 5155 0 Dermatology military 2922.0 18348 2478 52 Partner 34.3 282 470 0 Ophthalmology military...inpatient; ambulatory; dental ; ancillary; support services; and special programs. Two of these functional categories - ancillary and support services - are

  3. 24/7 Career Services: Where Practitioners Draw the Line between Their Professional and Personal Lives.

    ERIC Educational Resources Information Center

    Green, Marianne E.; Johansen, Karol A. D.; Wall, Jason

    2000-01-01

    Discusses survey results that reveal how practitioners handle requests for career advice from family and friends, and the issues that arise in the process. Results indicate that the majority of career services practitioners are comfortable offering career advice, including resume assistance, interviewing tips, and personal insight, to family and…

  4. 24/7 Career Services: Where Practitioners Draw the Line between Their Professional and Personal Lives.

    ERIC Educational Resources Information Center

    Green, Marianne E.; Johansen, Karol A. D.; Wall, Jason

    2000-01-01

    Discusses survey results that reveal how practitioners handle requests for career advice from family and friends, and the issues that arise in the process. Results indicate that the majority of career services practitioners are comfortable offering career advice, including resume assistance, interviewing tips, and personal insight, to family and…

  5. Point of care information services: a platform for self-directed continuing medical education for front line decision makers

    PubMed Central

    Moja, Lorenzo; Kwag, Koren Hyogene

    2015-01-01

    The structure and aim of continuing medical education (CME) is shifting from the passive transmission of knowledge to a competency-based model focused on professional development. Self-directed learning is emerging as the foremost educational method for advancing competency-based CME. In a field marked by the constant expansion of knowledge, self-directed learning allows physicians to tailor their learning strategy to meet the information needs of practice. Point of care information services are innovative tools that provide health professionals with digested evidence at the front line to guide decision making. By mobilising self-directing learning to meet the information needs of clinicians at the bedside, point of care information services represent a promising platform for competency-based CME. Several points, however, must be considered to enhance the accessibility and development of these tools to improve competency-based CME and the quality of care. PMID:25655251

  6. Canby Area Service Project substation and associated transmission line. Environmental Assessment

    SciTech Connect

    Not Available

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp`s substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC`s Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC`s substation can accommodate only about 10 percent of the expected additional electric load. BPA`s proposed action is intended to meet SVEC`s increasing electric load. BPA proposes to meet SVEC`s increasing energy load by tapping into BPA`s existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC`s Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no ``environmental impact statement`` is not required.

  7. Canby Area Service Project : Substation and Associated Transmission Line : Environmental Assessment.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-02-01

    Bonneville Power Administration (BPA) provides power to Surprise Valley Electrification Corporation (SVEC) in Modoc County, California. BPA uses PacificCorp's substation and transmission facilities between Alturas and Canby, California to transfer power to SVEC's Canby Substation. In the next year, SVEC expects increased industrial, agricultural, and residential electric loads on their 69-kV transmission system south of Canby. SVEC's substation can accommodate only about 10 percent of the expected additional electric load. BPA's proposed action is intended to meet SVEC's increasing electric load. BPA proposes to meet SVEC's increasing energy load by tapping into BPA's existing BPA Malin-Warner 230-kV transmission line, and building an 7.9-mile transmission line to a new BPA substation. BPA proposes to build the new substation next to the west side of SVEC's Canby Substation (Figure 1). This new substation will allow SVEC to move the additional power over their existing transmission or distribution lines. This report is the environmental assessment of the potential impact of the proposed project. The assessment determined that no environmental impact statement'' is not required.

  8. T cell-replacing factor- (TRF) induced IgG secretion in a human B blastoid cell line and demonstration of acceptors for TRF.

    PubMed

    Muraguchi, A; Kishimoto, T; Miki, Y; Kuritani, T; Kaieda, T; Yoshizaki, K; Yamamura, Y

    1981-08-01

    IgG-secretion was induced in a human B blastoid cell line, CESS, by the addition of partially purified T cell-derived helper factor(s) (TRF), which had been obtained from PHA-stimulated human T cells. The number of IgG-producing cells in CESS cells reached its maximal level (10% of total cells) within 48 hr after the addition of TRF. TRF did not affect the proliferation of CESS cells and the block of cell proliferation with hydroxyurea did not inhibit the increase of IgG-producing cells, showing that TRF induced IgG-production in CESS cells without any requirement of cell division. TRF activity was completely removed by CESS cells but TCGF-activity in the same preparation was not absorbed with CESS cells. On the other hand, TCGF-dependent human killer cells absorbed TCGF activity but not TRF activity in the same preparation. The binding of 125I-labeled factor(s) on CESS cells was also demonstrated. These results showed the presence of acceptors for TRF on the surface of CESS cells and this cell line will provide useful means for the chemical characterization of acceptors and for the study of the mechanisms of the signal transmission through acceptors.

  9. Proceedings of the First Workshop on Service-Oriented Architectures and Software Product Lines

    DTIC Science & Technology

    2008-05-01

    examples or a comparison of models (e.g, feature models versus SDL/BPEL/Business Process modeling notation ( BPMN )?” Response: The authors were not...the business level and then, from the re- quirements, deriving service composition automatically [25]. Business Process Model- ing Notation ( BPMN ) [6...of OMG provides notation for a high-level description of a business process. In addition, a mapping from BPMN to BPEL providing automatic

  10. Prioritizing equipment for replacement.

    PubMed

    Capuano, Mike

    2010-01-01

    It is suggested that clinical engineers take the lead in formulating evaluation processes to recommend equipment replacement. Their skill, knowledge, and experience, combined with access to equipment databases, make them a logical choice. Based on ideas from Fennigkoh's scheme, elements such as age, vendor support, accumulated maintenance cost, and function/risk were used.6 Other more subjective criteria such as cost benefits and efficacy of newer technology were not used. The element of downtime was also omitted due to the data element not being available. The resulting Periop Master Equipment List and its rationale was presented to the Perioperative Services Program Council. They deemed the criteria to be robust and provided overwhelming acceptance of the list. It was quickly put to use to estimate required capital funding, justify items already thought to need replacement, and identify high-priority ranked items for replacement. Incorporating prioritization criteria into an existing equipment database would be ideal. Some commercially available systems do have the basic elements of this. Maintaining replacement data can be labor-intensive regardless of the method used. There is usually little time to perform the tasks necessary for prioritizing equipment. However, where appropriate, a clinical engineering department might be able to conduct such an exercise as shown in the following case study.

  11. ARRANGEMENT FOR REPLACING FILTERS

    DOEpatents

    Blomgren, R.A.; Bohlin, N.J.C.

    1957-08-27

    An improved filtered air exhaust system which may be continually operated during the replacement of the filters without the escape of unfiltered air is described. This is accomplished by hermetically sealing the box like filter containers in a rectangular tunnel with neoprene covered sponge rubber sealing rings coated with a silicone impregnated pneumatic grease. The tunnel through which the filters are pushed is normal to the exhaust air duct. A number of unused filters are in line behind the filters in use, and are moved by a hydraulic ram so that a fresh filter is positioned in the air duct. The used filter is pushed into a waiting receptacle and is suitably disposed. This device permits a rapid and safe replacement of a radiation contaminated filter without interruption to the normal flow of exhaust air.

  12. [Development of a service on line advice and information technology management for health].

    PubMed

    Berrospi Polo, Victor; Rodriguez Abad, Juan; Bobadilla Aguilar, Juan; Di Liberto Moreno, Carlos; Díaz Arroyo, Cecilia; Rafael Quipan, Carlos

    2015-10-01

    To validate an advisory service and online information technology management for health and helps to make assessment and acquisition processes an informed medical equipment according to the market and the needs of the health institutions. Internet via a technological solution supported ona data base containing systematic and updated information on technical specifications of 25 compared medical equipment, the same reference prices, list of suppliers, agents and / or producers and technical standards are developed. The"virtual" technical assistance was made with the support of a team of specialists in Health Technology Management, the decision makers in the planning, evaluation and procurement of biomedical equipment. The validation of the service was conducted by involving specialists in the field of Health Technology Management, from different disciplines and institutions who worked in health, public and private. They used the service for a period of time to verify its feasibility of use as well as its usefulness for their planning, evaluation and procurement of biomedical equipment. To these experts we applied a survey before and after them about the software developed in this project. We found that it is common to use the internet to search for information on medical equipment.Also,an increase on the view that the application will help in procurement of biomedical equipment(40% to 78%) was observed, it will improve the information system(40% to 89%) and communication among physicians,nurses, planners, engineers and other professionals involved in this process(20% to 78%). There is a need for a technological tool available with such features contribute to technology management in Peru.

  13. Shortened first-line TB treatment in Brazil: potential cost savings for patients and health services.

    PubMed

    Trajman, Anete; Bastos, Mayara Lisboa; Belo, Marcia; Calaça, Janaína; Gaspar, Júlia; Dos Santos, Alexandre Martins; Dos Santos, Camila Martins; Brito, Raquel Trindade; Wells, William A; Cobelens, Frank G; Vassall, Anna; Gomez, Gabriela B

    2016-01-22

    Shortened treatment regimens for tuberculosis are under development to improve treatment outcomes and reduce costs. We estimated potential savings from a societal perspective in Brazil following the introduction of a hypothetical four-month regimen for tuberculosis treatment. Data were gathered in ten randomly selected health facilities in Rio de Janeiro. Health service costs were estimated using an ingredient approach. Patient costs were estimated from a questionnaire administered to 126 patients. Costs per visits and per case treated were analysed according to the type of therapy: self-administered treatment (SAT), community- and facility-directly observed treatment (community-DOT, facility-DOT). During the last 2 months of treatment, the largest savings could be expected for community-DOT; on average USD 17,351-18,203 and USD 43,660-45,856 (bottom-up and top-down estimates) per clinic. Savings to patients could also be expected as the median (interquartile range) patient-related costs during the two last months were USD 108 (13-291), USD 93 (36-239) and USD 11 (7-126), respectively for SAT, facility-DOT and community-DOT. Introducing a four-month regimen may result in significant cost savings for both the health service and patients, especially the poorest. In particular, a community-DOT strategy, including treatment at home, could maximise health services savings while limiting patient costs. Our cost estimates are likely to be conservative because a 4-month regimen could hypothetically increase the proportion of patients cured by reducing the number of patients defaulting and we did not include the possible cost benefits from the subsequent prevention of costs due to downstream transmission averted and rapid clinical improvement with less side effects in the last two months.

  14. NASA Turbulence Technologies In-Service Evaluation: Delta Air Lines Report-Out

    NASA Technical Reports Server (NTRS)

    Amaral, Christian; Dickson, Steve; Watts, Bill

    2007-01-01

    Concluding an in-service evaluation of two new turbulence detection technologies developed in the Turbulence Prediction and Warning Systems (TPAWS) element of the NASA Aviation Safety and Security Program's Weather Accident Prevention Project (WxAP), this report documents Delta's experience working with the technologies, feedback gained from pilots and dispatchers concerning current turbulence techniques and procedures, and Delta's recommendations regarding directions for further efforts by the research community. Technologies evaluated included an automatic airborne turbulence encounter reporting technology called the Turbulence Auto PIREP System (TAPS), and a significant enhancement to the ability of modern airborne weather radars to predict and display turbulence of operational significance, called E-Turb radar.

  15. B Plant process piping replacement feasibility study

    SciTech Connect

    Howden, G.F.

    1996-02-07

    Reports on the feasibility of replacing existing embedded process piping with new more corrosion resistant piping between cells and between cells and a hot pipe trench of a Hanford Site style canyon facility. Provides concepts for replacement piping installation, and use of robotics to replace the use of the canyon crane as the primary means of performing/supporting facility modifications (eg, cell lining, pipe replacement, equipment reinstallation) and operational maintenenace.

  16. The Medication Information Line for the Elderly. A consumer/health care professional-oriented drug information service.

    PubMed

    Grymonpré, R E; Steele, J W; Schultz, B R

    1987-05-01

    The experiences of a drug information telephone service aimed at older adults, their care providers, and health care professionals are presented. The Medication Information Line for the Elderly received 1,561 telephone calls over the 12 months since its opening. The majority of callers (73%) were female and 723 (46%) of the 1,561 calls came from people in the 65 to 79 age group. Nearly one-third of all enquiries were about suspected drug-related adverse drug reactions. The drugs most commonly causing concern (as classified by the American Hospital Formulary Service) were nonsteroidal anti-inflammatory drugs, cardiac drugs, and benzodiazepines; a list comparable to the most frequently prescribed drugs in older adults. The pharmacist was able to respond to 853 (27%) of the 3,172 enquiries without reference material. The most frequently used sources of information were the USP Drug information, Volumes I & II, and the Compendium of Pharmaceuticals and Specialties. Follow-up calls on certain consumer enquiries indicated that 89% of the recommendations were adhered to, suggesting a beneficial influence of this type of drug information service on medication use.

  17. Kearns-Tribune Corp. vs. Public Service Commission: tag-line. you're not it

    SciTech Connect

    Riley, R.

    1985-01-01

    The tagline rule under the Public Utility Regulatory Policies Act (PURPA) of 1978 attempted to alleviate ratepayer concern over utility advertising costs by requiring certain ads to include information identifying the source of funding. The Utah Supreme Court ruled in the Kearns-Tribune Corp. case that the Public Service Commission (PSC) had no statutory authority to impose the tagline rule. The author examines the general background of the utility advertising problem, then discusses Utah case law in light of the Court's three-part analysis of the case. She concludes that the court will examine whether regulatory measures are closely connected to specific statutes in the future. If the court finds even a questionable degree of intrusiveness in utility management by the PSC, it is likely to launch an extensive search for alternative measures.

  18. The stigma of obesity in customer service: a mechanism for remediation and bottom-line consequences of interpersonal discrimination.

    PubMed

    King, Eden B; Shapiro, Jenessa R; Hebl, Michelle R; Singletary, Sarah L; Turner, Stacey

    2006-05-01

    Using a customer service paradigm, the authors extended the justification-suppression model (JSM) of prejudice (C. S. Crandall & A. Eshleman, 2003) to include contemporary, covert forms of discrimination and to identify a discrimination remediation mechanism. Overall, the results of 3 studies revealed that actual and confederate obese shoppers in high-prejudice justification conditions faced more interpersonal discrimination than average-weight shoppers. Furthermore, Studies 1 and 2 demonstrate that adopting strategies that remove perceivers' justifications for discriminating against obese individuals (i.e., the controllability of weight) decreases the incidence of interpersonal discrimination. Additionally, Study 3 demonstrates negative bottom-line consequences of interpersonal discrimination for organizations (e.g., customer loyalty, purchasing behavior). Together, these studies confirm that the JSM applies to covert forms of discrimination, show the importance of examining subtle discrimination, and offer a mechanism for theory-driven strategies for the reduction of covert forms of discrimination.

  19. The Application of Waiting Lines System in Improving Customer Service Management: The Examination of Malaysia Fast Food Restaurants Industry

    NASA Astrophysics Data System (ADS)

    Ismail, Zurina; Shokor, Shahrul Suhaimi AB

    2016-03-01

    Rapid life time change of the Malaysian lifestyle had served the overwhelming growth in the service operation industry. On that occasion, this paper will provide the idea to improve the waiting line system (WLS) practices in Malaysia fast food chains. The study will compare the results in between the single server single phase (SSSP) and the single server multi-phase (SSMP) which providing Markovian Queuing (MQ) to be used for analysis. The new system will improve the current WLS, plus intensifying the organization performance. This new WLS were designed and tested in a real case scenario and in order to develop and implemented the new styles, it need to be focusing on the average number of customers (ANC), average number of customer spending time waiting in line (ACS), and the average time customers spend in waiting and being served (ABS). We introduced new WLS design and there will be prompt discussion upon theories of benefits and potential issues that will benefit other researchers.

  20. A measurement-driven approach to assess power line telecommunication (PLT) network quality of service (QoS) performance parameters

    NASA Astrophysics Data System (ADS)

    Betta, G.; Capriglione, D.; Ferrigno, L.; Laracca, M.

    2009-10-01

    Power line telecommunication (PLT) technology offers cheap and fast ways for providing in-home broadband services and local area networking. Its main advantage is due to the possibility of using the pre-existing electrical grid as a communication channel. Nevertheless, technical challenges arise from the difficulty of operating on a hostile medium, not designed for communication purposes, characterized by complex channel modeling and by varying time response. These aspects put practical problems for designers and testers in the assessment of network quality of service performance parameters such as the throughput, the latency, the jitter, and the reliability. The measurement of these parameters has not yet been standardized so that there do not exist reference test set-ups and measurement methodologies (i.e. the type of isolation from the ac main, the observation time and the number of experiments, the measurement uncertainty and so on). Consequently, experiments executed by adopting different methods may lead to incompatible measurement results, thus making it also impossible to have reliable comparisons of different PLT modems. Really, the development of standard procedures is a very difficult task because the scenarios in which the PLT modems can work are very wide and then the application of an exhaustive approach (in which all the parameters influencing the PLT performance should be considered) would be very complex and time consuming, thus making the modem characterization very expensive. In this paper, the authors propose a methodological approach to develop an efficient measurement procedure able to reliably assess the performance of PLT modems (in terms of network quality of service parameters) with a minimum number of experiments. It is based on both creating a reconfigurable grid to which real disturbing loads are connected and implementing an original design of the experiment technique based on the effects of the uncertainty of the measurement results

  1. Implementation of the affordable care act: a case study of a service line co-management company.

    PubMed

    Lanese, Bethany

    2016-09-19

    Purpose The purpose of this paper is to test and measure the outcome of a community hospital in implementing the Affordable Care Act (ACA) through a co-management arrangement. RQ1: do the benefits of a co-management arrangement outweigh the costs? RQ2: does physician alignment aid in the effective implementation of the ACA directives set for hospitals? Design/methodology/approach A case study of a 350-bed non-profit community hospital co-management company. The quantitative data are eight quarters of quality metrics prior and eight quarters post establishment of the co-management company. The quality metrics are all based on standardized national requirements from the Joint Commission and Centers for Medicare and Medicaid Services guidelines. These measures directly impact the quality initiatives under the ACA that are applicable to all healthcare facilities. Qualitative data include survey results from hospital employees of the perceived effectiveness of the co-management company. A paired samples difference of means t-test was conducted to compare the timeframe before co-management and post co-management. Findings The findings indicate that the benefits of a co-management arrangement do outweigh the costs for both the physicians and the hospital ( RQ1). The physicians benefit through actual dollar payout, but also with improved communication and greater input in running the service line. The hospital benefits from reduced cost - or reduced penalties under the ACA - as well as better communication and greater physician involvement in administration of the service line. RQ2: does physician alignment aid in the effective implementation of the ACA directives set for hospitals? The hospital improved in every quality metric under the co-management company. A paired sample difference of means t-test showed a statistically significant improvement in five of the six quality metrics in the study. Originality/value Previous research indicates the potential effectiveness of

  2. Testing of Replacement Bag Material

    SciTech Connect

    Laurinat, J.E.

    1998-11-03

    Recently, the FB-Line bagout material was changed to simplify the processing of sand, slag, and crucible.The results of the strength tests and the outgassing measurements and calculations demonstrate that the proposed replacement nylon bag materials (HRMP and orange anti-static material) are acceptable substitutes for LDPE and the original nylon with respect to mechanical properties.

  3. Can consumer choice replace trust in the National Health Service in England? Towards developing an affective psychosocial conception of trust in health care.

    PubMed

    Fotaki, Marianna

    2014-11-01

    Trust has long been regarded as a vitally important aspect of the relationship between health service providers and patients. Recently, consumer choice has been increasingly advocated as a means of improving the quality and effectiveness of health service provision. However, it is uncertain how the increase of information necessary to allow users of health services to exercise choice, and the simultaneous introduction of markets in public health systems, will affect various dimensions of trust, and how changing relations of trust will impact upon patients and services. This article employs a theory-driven approach to investigate conceptual and material links between choice, trust and markets in health care in the context of the National Health Service in England. It also examines the implications of patient choice on systemic, organisational and interpersonal trust. The article is divided into two parts. The first argues that the shift to marketisation in public health services might lead to an over-reliance on rational-calculative aspects of trust at the expense of embodied, relational and social attributes. The second develops an alternative psychosocial conception of trust: it focuses on the central role of affect and accounts for the material and symbolic links between choice, trust and markets in health care.

  4. Nicotine replacement therapy

    MedlinePlus

    ... nicotine replacement product, even for a short time. Alternative Names Smoking cessation - nicotine replacement; Tobacco - nicotine replacement therapy References American Cancer Society. Guide to quitting smoking. Last revised February ...

  5. Shoulder replacement - discharge

    MedlinePlus

    ... page: //medlineplus.gov/ency/patientinstructions/000178.htm Shoulder replacement - discharge To use the sharing features on this page, please enable JavaScript. You had shoulder replacement surgery to replace the bones of your shoulder ...

  6. Hip replacement - discharge

    MedlinePlus

    ... surgery to replace all or part of your hip joint with an artificial joint called a prosthesis. This ... You're in the Hospital You had a hip joint replacement surgery to replace all or part of ...

  7. Low contribution of PbO2-coated lead service lines to water lead contamination at the tap.

    PubMed

    Triantafyllidou, Simoni; Schock, Michael R; DeSantis, Michael K; White, Colin

    2015-03-17

    To determine if residential water sampling corroborates the expectation that formation of stable PbO2 coatings on lead service lines (LSLs) provides an effective lead release control strategy, lead profile sampling was evaluated for eight home kitchen taps in three U.S. cities with observed PbO2-coated LSLs (Newport, Rhode Island; Cincinnati and Oakwood, Ohio). After various water standing times, these LSLs typically released similar or lower peak lead levels (1 to 18 μg/L) than the lead levels from the respective kitchen faucets (1 to 130 μg/L), and frequently 50-80% lower than the lead levels typically reported from Pb(II)-coated LSLs in comparable published sampling studies. Prolonged stagnation (10-101 h) at the Cincinnati sites produced varying results. One site showed minimal (0-4 μg/L) increase in lead release from the PbO2-coated LSL, and persistence of free chlorine residual. However, the other site showed up to a 3-fold increase proportional to standing time, with essentially full depletion of the chlorine residual. Overall, lead release was consistently much lower than that reported in studies of Pb(II)-coated LSL scales, suggesting that natural formation of PbO2 in LSLs is an effective lead "corrosion" control strategy.

  8. Aerocoat 7 Replacement Coatings

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Kennedy Space Center has used Aerocoat 7 (AR-7) to protect stainless-steel flex hoses at Launch Complex (LC-39) and hydraulic lines of the Mobile Launcher Platform (MLP) because it provides excellent corrosion protection in low-temperature applications. The Sovereign Company produced AR-7 exclusively for NASA but discontinued production because the coating released high levels of volatile organic compounds (VOCs) and had a significant environmental impact. The purpose of this project was to select and evaluate potential replacement coatings for AR-7 that would be more environmentally sound. The physical and mechanical properties of commercially available coatings were investigated through the Internet. The ideal coating would be fluid enough to penetrate the outer mesh of a stainless-steel flex hose and coat the inner hose, and flexible enough to withstand the movement of the hose, as well as the expansion and contraction of its metal caused by changes in temperature.

  9. Optimization of station battery replacement

    NASA Astrophysics Data System (ADS)

    Jancauskas, J. R.; Shook, D. A.

    1994-08-01

    During a loss of ac power at a nuclear generating station (including diesel generators), batteries provide the source of power which is required to operate safety-related components. Because traditional lead-acid batteries have a qualified life of 20 years, the batteries must be replaced a minimum of once during a station's lifetime, twice if license extension is pursued, and more often depending on actual in-service dates and the results of surveillance tests. Replacement of batteries often occurs prior to 20 years as a result of systems changes caused by factors such as Station Blackout Regulations, control system upgrades, incremental load growth, and changes in the operating times of existing equipment. Many of these replacement decisions are based on the predictive capabilities of manual design basis calculations. The inherent conservatism of manual calculations may result in battery replacements occurring before actually required. Computerized analysis of batteries can aid in optimizing the timing of replacements as well as in interpreting service test data. Computerized analysis also provides large benefits in maintaining the as-configured load profile and corresponding design margins, while also providing the capability to quickly analyze proposed modifications and respond to internal and external audits.

  10. The CDS information hub. On-line services and links at the Centre de Données astronomiques de Strasbourg

    NASA Astrophysics Data System (ADS)

    Genova, F.; Egret, D.; Bienaymé, O.; Bonnarel, F.; Dubois, P.; Fernique, P.; Jasniewicz, G.; Lesteven, S.; Monier, R.; Ochsenbein, F.; Wenger, M.

    2000-04-01

    The Centre de données astronomiques de Strasbourg (CDS) provides homogeneous access to heterogeneous information of various origins: information about astronomical objects in Simbad; catalogs and observation logs in VizieR and in the catalogue service; reference images and overlays in Aladin; nomenclature in the Dictionary of Nomenclature; Yellow Page services; the AstroGLU resource discovery tool; mirror copies of other reference services; and documentation. With the implementation of links between the CDS services, and with other on-line reference information, CDS has become a major hub in the rapidly evolving world of information retrieval in astronomy, developing efficient tools to help astronomers to navigate in the world-wide ``Virtual Observatory'' under construction, from data in the observatory archives to results published in journals. The WWW interface to the CDS services is available at: http://cdsweb.u-strasbg.fr/

  11. 49 CFR 1242.76 - Administration; pickup and delivery, marine line haul, and rail substitute service; loading...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... haul, and rail substitute service; loading, unloading and local marine; protective services; freight lost or damaged-solely related; fringe benefits; casualties and insurance; joint facility, and other... SEPARATION OF COMMON OPERATING EXPENSES BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS...

  12. C-lines of stocking for southern bottomland hardwoods: A guide to identifying insufficient stocking. Forest Service research note

    SciTech Connect

    Goetz, J.C.G.

    1997-07-01

    A B-line on a stocking chart represents suggested residual stocking after thinning, or minimum full stocking. A stand at the C-line on a stocking chart will achieve the B-line after a period of growth usually specified as 10 years. Four C-lines that reflect insufficient stocking of southern bottomland hardwoods are presented. These C-line represent 10, 15, 20, and 25 years to reach B-line stocking. Alternative C-lines may be used to determine different silvicultural opportunities--the C-line based on 10 years may be used to identify stands that do not require intervention in the near future; a C-line based on 20 years may be used to identify stands requiring regeneration.

  13. Power Plant Replacement Study

    SciTech Connect

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University's aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  14. Power Plant Replacement Study

    SciTech Connect

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University’s aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  15. Power Plant Replacement Study

    SciTech Connect

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self-funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University’s aging and failing circa 1925 central steam production plant. Twenty-three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  16. Power Plant Replacement Study

    SciTech Connect

    Reed, Gary

    2010-09-30

    This report represents the final report for the Eastern Illinois University power plant replacement study. It contains all related documentation from consideration of possible solutions to the final recommended option. Included are the economic justifications associated with the chosen solution along with application for environmental permitting for the selected project for construction. This final report will summarize the results of execution of an EPC (energy performance contract) investment grade audit (IGA) which lead to an energy services agreement (ESA). The project includes scope of work to design and install energy conservation measures which are guaranteed by the contractor to be self‐funding over its twenty year contract duration. The cost recovery is derived from systems performance improvements leading to energy savings. The prime focus of this EPC effort is to provide a replacement solution for Eastern Illinois University’s aging and failing circa 1925 central steam production plant. Twenty‐three ECMs were considered viable whose net impact will provide sufficient savings to successfully support the overall project objectives.

  17. HST Replacement Battery Initial Performance

    NASA Technical Reports Server (NTRS)

    Krol, Stan; Waldo, Greg; Hollandsworth, Roger

    2009-01-01

    The Hubble Space Telescope (HST) original Nickel-Hydrogen (NiH2) batteries were replaced during the Servicing Mission 4 (SM4) after 19 years and one month on orbit.The purpose of this presentation is to highlight the findings from the assessment of the initial sm4 replacement battery performance. The batteries are described, the 0 C capacity is reviewed, descriptions, charts and tables reviewing the State Of Charge (SOC) Performance, the Battery Voltage Performance, the battery impedance, the minimum voltage performance, the thermal performance, the battery current, and the battery system recharge ratio,

  18. 30 CFR 823.14 - Soil replacement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Soil replacement. (a) Soil reconstruction specifications established by the U.S. Soil Conservation Service shall be based upon the standards of the National Cooperative Soil Survey and shall include, as a... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Soil replacement. 823.14 Section 823.14 Mineral...

  19. 30 CFR 823.14 - Soil replacement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Soil replacement. (a) Soil reconstruction specifications established by the U.S. Soil Conservation Service shall be based upon the standards of the National Cooperative Soil Survey and shall include, as a... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Soil replacement. 823.14 Section 823.14 Mineral...

  20. 30 CFR 823.14 - Soil replacement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Soil replacement. (a) Soil reconstruction specifications established by the U.S. Soil Conservation Service shall be based upon the standards of the National Cooperative Soil Survey and shall include, as a... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Soil replacement. 823.14 Section 823.14 Mineral...

  1. 30 CFR 823.14 - Soil replacement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Soil replacement. (a) Soil reconstruction specifications established by the U.S. Soil Conservation Service shall be based upon the standards of the National Cooperative Soil Survey and shall include, as a... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Soil replacement. 823.14 Section 823.14 Mineral...

  2. 30 CFR 823.14 - Soil replacement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Soil replacement. (a) Soil reconstruction specifications established by the U.S. Soil Conservation Service shall be based upon the standards of the National Cooperative Soil Survey and shall include, as a... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Soil replacement. 823.14 Section 823.14 Mineral...

  3. 7 CFR 1944.659 - Replacement housing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Replacement housing. 1944.659 Section 1944.659 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.659 Replacement...

  4. 7 CFR 1944.659 - Replacement housing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 13 2014-01-01 2013-01-01 true Replacement housing. 1944.659 Section 1944.659 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.659 Replacement...

  5. 7 CFR 1944.659 - Replacement housing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Replacement housing. 1944.659 Section 1944.659 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.659 Replacement...

  6. FEDIX On-Line Information Service: Implementation of a Government-wide on-line research and educational opportunity information initiative for the education community. Final report for DOE Cooperative Agreement DE-FC02-89ER75527

    SciTech Connect

    Rodman, John A.

    1999-12-01

    FEDIX is an on-line information retrieval service of federal opportunities for colleges and universities supported by multiple federal agencies as an outreach tool to promote enhanced communication to colleges, universities, and other educational and research organizations regarding federal research, and educational opportunities. Multiple attachments include several annual progress reports, a listing of sample FEDIX outreach meetings and conferences, results from user satisfaction surveys, usage statistics, and FEDIX handouts.

  7. A minority research and education information service: Design, develop, pilot test, and implement on-line access for historically black colleges and universities and government agencies

    SciTech Connect

    Rodman, J.A.

    1992-01-01

    This Annual Status Report describes the design, development and implementation of the Minority On-Line Information Service (MOLIS) project by Federal Information Exchange, Inc. for the period of April 1, 1991 to March 31, 1992. Summary information detailing developments prior to this reporting period will also be included to establish a comprehensive perspective of the project. The goal of the MOLIS project, was to develop, design, pilot test on-line access to current information on minority colleges and universities and federal minority opportunities. Federal Information Exchange, Inc. (FIE), a diversified information services company recognized by researchers and educators as a leader in the field of information delivery services, was awarded a 5 year small business research grant to develop and implement MOLIS. Since April 29, 1991, the inauguration of its on-line service, MOLIS has provided current information on 138 Black and Hispanic colleges and universities -- including faculty and student profiles, financial data, research centers and equipment information, pre-college and education programs, emerging capabilities, enrollment data, administrative personnel data, and current events -- as well as minority opportunities from 8 participating federal agencies.

  8. 77 FR 9960 - Final Environmental Impact Statement for Extension of F-Line Streetcar Service to Fort Mason...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... Fort Mason Center, San Francisco, CA AGENCY: National Park Service, Department of the Interior. ACTION... Service to Fort Mason Center, San Francisco, California. SUMMARY: Pursuant to National Environmental... Wharf to the Fort Mason Center, in San Francisco, California. DATES: The National Park Service (NPS...

  9. Treating moderate acute malnutrition in first-line health services: an effectiveness cluster-randomized trial in Burkina Faso.

    PubMed

    Nikièma, Laetitia; Huybregts, Lieven; Kolsteren, Patrick; Lanou, Hermann; Tiendrebeogo, Simon; Bouckaert, Kimberley; Kouanda, Séni; Sondo, Blaise; Roberfroid, Dominique

    2014-07-01

    Management of moderate acute malnutrition (MAM) is, currently, focused on food supplementation approaches. However, the sustainability of these strategies remains weak in low- and middle-income countries. In food-secure settings, an educational/behavioral intervention could be an alternative for improving MAM management. This study compared the effectiveness of weekly context-appropriate child-centered counseling (CCC), with an improved corn-soy blend [corn-soy blend with added micronutrients (CSB++)] or a locally produced ready-to-use supplementary food (RUSF), in treating MAM through first-line rural health services. We used a cluster randomized controlled trial design with 3 arms, involving 18 rural health centers (6 by arm) and children aged 6-24 mo with uncomplicated MAM. In the first arm (CCC), trained health workers provided weekly personalized counseling to caretakers. In the 2 other arms, children received weekly either 455 g CSB++ or 350 g locally produced soy-based RUSF. Both food supplements provided ∼250 kcal/d. The recovery rate after 3 mo of treatment was significantly lower with CCC (57.8%) than with CSB++ (74.5%) and RUSF (74.2%) (P < 0001). Mothers' attendance at health facilities was also substantially lower in the CCC arm (P < 0001); this arm had a high defaulter rate (P < 0.003). When the analysis was adjusted for attendance, we did not find a significant difference between the 3 arms, with incidence rate ratios of 1.14 (95% CI: 0.99, 1.31) and 1.13 (95% CI: 0.98, 1.30) for the CSB++ and RUSF arms, respectively, compared with the CCC arm. Whereas supplement-based treatment of MAM was found to be more effective than the provision of CCC, we hypothesize that appropriate and specific nutrition counseling centered on children's needs, through primary health facilities, might be an alternative strategy for MAM treatment in rural food-secure areas, provided that attendance at counseling sessions by the caregiver is ensured. This trial was

  10. 41 CFR 109-25.401-50 - Replacement approvals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND... of Administrative Services and heads of field organizations are authorized to approve replacement of...

  11. 41 CFR 109-25.401-50 - Replacement approvals.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND... of Administrative Services and heads of field organizations are authorized to approve replacement of...

  12. The feasibility of replacing or upgrading utility distribution transformers during routine maintenance

    SciTech Connect

    Barnes, P.R.; Van Dyke, J.W.; McConnell, B.W.; Cohn, S.M.; Purucker, S.L.

    1995-04-01

    It is estimated that electric utilities use about 40 million distribution transformers in supplying electricity to customers in the United States. Although utility distribution transformers collectively have a high average efficiency, they account for approximately 61 billion kWh of the 229 billion kWh of energy lost annually in the delivery of electricity. Distribution transformers are being replaced over time by new, more efficient, lower-loss units during routine utility maintenance of power distribution systems. Maintenance is typically not performed on units in service. However, units removed from service with appreciable remaining life are often refurbished and returned to stock. Distribution transformers may be removed from service for many reasons, including failure, over- or underloading, or line upgrades such as voltage changes or rerouting. When distribution transformers are removed from service, a decision must be made whether to dispose of the transformer and purchase a lower-loss replacement or to refurbish the transformer and return it to stock for future use. This report contains findings and recommendations on replacing utility distribution transformers during routine maintenance, which is required by section 124(c) of the Energy Policy Act of 1992. The objectives of the study are to evaluate the practicability, cost-effectiveness, and potential energy savings of replacing or upgrading existing transformers during routine utility maintenance and to develop recommendations on was to achieve the potential energy savings.

  13. Modeling the Structure of Partnership between Researchers and Front-Line Service Providers: Strengthening Collaborative Public Health Research

    ERIC Educational Resources Information Center

    Pinto, Rogério M.; Wall, Melanie M.; Spector, Anya Y.

    2014-01-01

    Partnerships between HIV researchers and service providers are essential for reducing the gap between research and practice. Community-Based Participatory Research principles guided this cross-sectional study, combining 40 in-depth interviews with surveys of 141 providers in 24 social service agencies in New York City. We generated the…

  14. Modeling the Structure of Partnership between Researchers and Front-Line Service Providers: Strengthening Collaborative Public Health Research

    ERIC Educational Resources Information Center

    Pinto, Rogério M.; Wall, Melanie M.; Spector, Anya Y.

    2014-01-01

    Partnerships between HIV researchers and service providers are essential for reducing the gap between research and practice. Community-Based Participatory Research principles guided this cross-sectional study, combining 40 in-depth interviews with surveys of 141 providers in 24 social service agencies in New York City. We generated the…

  15. Medical Services under the IDEA: A Bright Line Test, "Cedar Rapids Community School District v. Garret F."

    ERIC Educational Resources Information Center

    DeMitchell, Todd A.

    1999-01-01

    The U.S. Supreme Court decided that quadraplegics like Garret F. cannot enter the schoolhouse gate without supportive medical services--vastly different from ordinary nursing services. Are there limits to what government should provide for disabled students? This new responsibility level poses problems for schools and confounds Congress's original…

  16. Implementing a multifaceted intervention to decrease central line-associated bloodstream infections in SEHA (Abu Dhabi Health Services Company) intensive care units: the Abu Dhabi experience.

    PubMed

    Latif, Asad; Kelly, Bernadette; Edrees, Hanan; Kent, Paula S; Weaver, Sallie J; Jovanovic, Branislava; Attallah, Hadeel; de Grouchy, Kristin K; Al-Obaidli, Ali; Goeschel, Christine A; Berenholtz, Sean M

    2015-07-01

    OBJECTIVE To determine whether implementation of a multifaceted intervention would significantly reduce the incidence of central line-associated bloodstream infections. DESIGN Prospective cohort collaborative. SETTING AND PARTICIPANTS Intensive care units of the Abu Dhabi Health Services Company hospitals in the Emirate of Abu Dhabi. INTERVENTIONS A bundled intervention consisting of 3 components was implemented as part of the program. It consisted of a multifaceted approach that targeted clinician use of evidence-based infection prevention recommendations, tools that supported the identification of local barriers to these practices, and implementation ideas to help ensure patients received the practices. Comprehensive unit-based safety teams were created to improve safety culture and teamwork. Finally, the measurement and feedback of monthly infection rate data to safety teams, senior leaders, and staff in participating intensive care units was encouraged. The main outcome measure was the quarterly rate of central line-associated bloodstream infections. RESULTS Eighteen intensive care units from 7 hospitals in Abu Dhabi implemented the program and achieved an overall 38% reduction in their central line-associated bloodstream infection rate, adjusted at the hospital and unit level. The number of units with a quarterly central line-associated bloodstream infection rate of less than 1 infection per 1,000 catheter-days increased by almost 40% between the baseline and postintervention periods. CONCLUSION A significant reduction in the global morbidity and mortality associated with central line-associated bloodstream infections is possible across intensive care units in disparate settings using a multifaceted intervention.

  17. 39 CFR 777.24 - Replacement housing payments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Replacement housing payments. 777.24 Section 777... PROPERTY ACQUISITION POLICIES Uniform Relocation Assistance § 777.24 Replacement housing payments. (a) Residential displaced persons are eligible for replacement housing payments as follows: (1)...

  18. 39 CFR 777.24 - Replacement housing payments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Replacement housing payments. 777.24 Section 777... PROPERTY ACQUISITION POLICIES Uniform Relocation Assistance § 777.24 Replacement housing payments. (a) Residential displaced persons are eligible for replacement housing payments as follows: (1)...

  19. 39 CFR 777.24 - Replacement housing payments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Replacement housing payments. 777.24 Section 777... PROPERTY ACQUISITION POLICIES Uniform Relocation Assistance § 777.24 Replacement housing payments. (a) Residential displaced persons are eligible for replacement housing payments as follows: (1)...

  20. 39 CFR 777.24 - Replacement housing payments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Replacement housing payments. 777.24 Section 777... PROPERTY ACQUISITION POLICIES Uniform Relocation Assistance § 777.24 Replacement housing payments. (a) Residential displaced persons are eligible for replacement housing payments as follows: (1)...

  1. 47 CFR 97.29 - Replacement license grant document.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES AMATEUR RADIO SERVICE General Provisions § 97.29 Replacement license grant document. Each grantee whose amateur station license grant document is lost, mutilated or destroyed may apply to the FCC for a...

  2. 47 CFR 97.29 - Replacement license grant document.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES AMATEUR RADIO SERVICE General Provisions § 97.29 Replacement license grant document. Each grantee whose amateur station license grant document is lost, mutilated or destroyed may apply to the FCC for a...

  3. 47 CFR 97.29 - Replacement license grant document.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES AMATEUR RADIO SERVICE General Provisions § 97.29 Replacement license grant document. Each grantee whose amateur station license grant document is lost, mutilated or destroyed may apply to the FCC for a...

  4. 47 CFR 97.29 - Replacement license grant document.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES AMATEUR RADIO SERVICE General Provisions § 97.29 Replacement license grant document. Each grantee whose amateur station license grant document is lost, mutilated or destroyed may apply to the FCC for a...

  5. 47 CFR 97.29 - Replacement license grant document.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES AMATEUR RADIO SERVICE General Provisions § 97.29 Replacement license grant document. Each grantee whose amateur station license grant document is lost, mutilated or destroyed may apply to the FCC for a...

  6. [Childhood leukaemia in a residential area with a high-voltage power line: approach according to the Dutch Community Health Services' guideline 'Cancer Clusters'].

    PubMed

    Hegger, Carola; Reedijk, Ardine M J

    2013-01-01

    The new Dutch Community Health Services' (GGD) guideline titled 'Cancer Clusters' describes a phased plan for investigating reported cancer clusters. In each phase, attention is paid to both health and environmental issues and their possible links to one another. Throughout the entire cluster investigation, good risk communication is essential. In accordance with the new guideline, the Rotterdam-Rijnmond Public Health Services investigated the incidence of childhood leukaemia in a residential area as well as the data available on the high-voltage power line located there. More children in this residential area had been diagnosed with leukaemia than expected. However, the children had not been subjected to prolonged exposure to strong magnetic fields emitted from the high-voltage power line. With this type of cluster investigation, it is not possible to establish a causal relationship between childhood leukaemia and high-voltage power lines. However, the research did provide stakeholders insight into the health-and-environment situation and thereby, the opportunity to assess the situation appropriately and to act accordingly, if desired.

  7. Nashville Gas treads carefully to replace pipe

    SciTech Connect

    1997-06-01

    The private gas utility, Nashville Gas, was responsible for replacing damaged or inadequate 2- and 4-inch steel gas lines beneath Music City, USA. The line replacements required either size for size or upsizing. The first choice was directional drilling, which was quickly determined to be unpractical because of rocky soil conditions. The second option was open trenching. Undoubtedly, trenching would mean having to contend with angry residents and tourists, since gas lines ran beneath yards, mature trees, sidewalks, roadways, and railways. In addition to the negative social factors, trenching would require additional funds for substantial landscaping and pavement replacement. It at all possible, a no-dig alternative was desired. Nashville Gas found Grundomat piercing tools which create a bore, then pushes pipe back through it. These same tools can simultaneously pull in pipe. These tools were customized for the Nashville project.

  8. The NRW-Educational Server learn:line and the Corresponding Project for In-service Teacher Training.

    ERIC Educational Resources Information Center

    Schwarze, Monika

    Two years ago the educational server, learn:line, of North Rhine Westfalia started at the State Institute of School and Further Education in Soest, Germany. A special pedagogical concept was put into practice and a platform for different types of schools was built--a platform for information, communication and cooperation among teachers as well as…

  9. 75 FR 78928 - Limited Service Domestic Voyage Load Lines for River Barges on Lake Michigan, Delay of Effective...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... than 4 feet. Small Craft Advisories may also be issued when lake ice exists that could be hazardous to... Barges on Lake Michigan, Delay of Effective Date AGENCY: Coast Guard, DHS. ACTION: Notice of delay of... special load line regimes for certain river barges operating on Lake Michigan. This rule finalized interim...

  10. 7 CFR 1944.664 - Housing preservation and replacement housing assistance.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 13 2013-01-01 2013-01-01 false Housing preservation and replacement housing...) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) HOUSING...

  11. 78 FR 28622 - Notice of Approval of Record of Decision for Extending F-Line Streetcar Service to Fort Mason...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... Fort Mason Center, Golden Gate National Recreation Area and San Francisco Maritime National Historic... service to Fort Mason Center. The requisite no-action ``wait period'' was initiated on February 24, 2012... use; constructing a turnaround terminus at the Fort Mason Center; and installing appurtenant features...

  12. Early Intervention Special Instructors and Service Coordinators in One State: Characteristics, Professional Development, and Needed Lines of Inquiry

    ERIC Educational Resources Information Center

    Edwards, Nicole Megan; Gallagher, Peggy A.

    2016-01-01

    The success of Early Intervention (EI) programs (Part C, IDEA [Individuals with Disabilities Education Improvement Act of 2004]) for infants and toddlers with special needs (birth to 36 months) is largely influenced by the quality of direct service providers. Little is known, however, about characteristics of providers or involvement in training…

  13. Early Intervention Special Instructors and Service Coordinators in One State: Characteristics, Professional Development, and Needed Lines of Inquiry

    ERIC Educational Resources Information Center

    Edwards, Nicole Megan; Gallagher, Peggy A.

    2016-01-01

    The success of Early Intervention (EI) programs (Part C, IDEA [Individuals with Disabilities Education Improvement Act of 2004]) for infants and toddlers with special needs (birth to 36 months) is largely influenced by the quality of direct service providers. Little is known, however, about characteristics of providers or involvement in training…

  14. An Exploratory Study of Factors Affecting Usage of an On-Line Computer-Based Bibliographic Retrieval Service.

    ERIC Educational Resources Information Center

    Watt, James H., Jr.; Stefanov, Rebecca

    The situational and personal factors affecting the usage of a computer based information service by health care professionals are described. Of 166 health care professionals who were identified as potential users of MEDLINE at the University of Connecticut, 126 carried out one or more online searches. Pre-use and post-use questionnaires were…

  15. Integrating Content Literacy, Critical Literacy, and Service Learning: A Line of Research during a Decade-Long Odyssey.

    ERIC Educational Resources Information Center

    Maring, Gerald H.; Wiseman, Beau J.; Boxie, Paula

    This paper describes how the literacy methods course at Washington State University was modified in light of critical literacy and service learning perspectives. The goal has always been to teach preservice teachers literacy development strategies within units of instruction of their own design, units they construct that integrate content and…

  16. Radiation Source Replacement Workshop

    SciTech Connect

    Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

    2010-12-01

    This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

  17. Modeling the Structure of Partnership Between Researchers and Front-Line Service Providers: Strengthening Collaborative Public Health Research.

    PubMed

    Pinto, Rogério M; Wall, Melanie M; Spector, Anya Y

    2014-01-01

    Partnerships between HIV researchers and service providers are essential for reducing the gap between research and practice. Community-Based Participatory Research principles guided this cross-sectional study, combining 40 in-depth interviews with surveys of 141 providers in 24 social service agencies in New York City. We generated the Provider-Researcher Partnership Model to account for provider- and agency-level factors' influence on intentions to form partnerships with researchers. Providers preferred "balanced partnerships" in which researchers and providers allocated research tasks and procedures to reflect diverse knowledge/skill sets. An organizational culture that values research can help enhance providers' intentions to partner. Providers' intentions and priorities found in this study may encourage researchers to engage in and policy makers to fund collaborative research.

  18. Environmental Assessment, Finding of No Significant Impact/Finding of No Practicable Alternative for Replacement of Overhead Electrical Line, Feeders K1 and K7, Vandenberg Air Force Base, California

    DTIC Science & Technology

    2012-09-19

    Mexican to the U.S. caused substantial changes in land ownership. Sheep ranching and grain farming replaced the old rancho system . Increased...3.4.1 Soils Vandenberg AFB is characterized by coastal sand dunes and alluvium (i.e., sediment deposited by flowing water). Vandenberg AFB is...in removal of vegetation and associated soil disturbance; thus, temporarily exacerbating the potential for erosion-induced sedimentation of Cañada

  19. Shielded balanced and coaxial transmission lines. Parametric measurements and instrumentation relevant to signal waveform transmission in digital service

    NASA Astrophysics Data System (ADS)

    Gans, W. L.; Nahman, N. S.

    1981-06-01

    The impulse and step responses of a shielded cable using time domain terminal measurements and a physically based mathematical model for the transmission line properties of the cable are determined. A computer controlled time domain measurement system was implemented using the automatic pulse measurement system. Data are also developed for the frequency domain complex propagation function (attenuation and its related minimum phase shift). The method is applied to 12 shielded paired conductor (balanced) cables and 5 coaxial cables. Time domain responses are presented for three nominal cable lengths, 60 m (200 ft), 150 m (500 ft), and 300 m (1000 ft).

  20. Ankle replacement - discharge

    MedlinePlus

    ... ankle replacement. Your surgeon removed and reshaped damaged bones, and put in an artificial ankle joint. You received pain medicine and were shown how to treat swelling around your new ankle joint.

  1. Carbohydrates as Fat Replacers.

    PubMed

    Peng, Xingyun; Yao, Yuan

    2017-02-28

    The overconsumption of dietary fat contributes to various chronic diseases, which encourages attempts to develop and consume low-fat foods. Simple fat reduction causes quality losses that impede the acceptance of foods. Fat replacers are utilized to minimize the quality deterioration after fat reduction or removal to achieve low-calorie, low-fat claims. In this review, the forms of fats and their functions in contributing to food textural and sensory qualities are discussed in various food systems. The connections between fat reduction and quality loss are described in order to clarify the rationales of fat replacement. Carbohydrate fat replacers usually have low calorie density and provide gelling, thickening, stabilizing, and other texture-modifying properties. In this review, carbohydrates, including starches, maltodextrins, polydextrose, gums, and fibers, are discussed with regard to their interactions with other components in foods as well as their performances as fat replacers in various systems.

  2. Replacing a Missing Tooth

    MedlinePlus

    ... vessels in the tooth pulps are rather large. Drilling down these teeth for crowns may expose the ... porcelain replacement tooth is held in place by metal extensions cemented to the backs of the adjacent ...

  3. Artificial Disc Replacement

    MedlinePlus

    ... treat this condition, alternatives to disc replacement include fusion, nonoperative care or no treatment. Typically, surgery is ... operative treatment for disc pain has been spinal fusion. This is a surgical procedure in which disc ...

  4. Hormone Replacement Therapy

    MedlinePlus

    ... before and during menopause, the levels of female hormones can go up and down. This can cause ... hot flashes and vaginal dryness. Some women take hormone replacement therapy (HRT), also called menopausal hormone therapy, ...

  5. Artificial Disc Replacement

    MedlinePlus

    ... also disc replacements designed for use in the cervical spine (the neck). These devices have only been used ... of your spine increases the risk of significant injury during this type of spinal surgery. Back pain ...

  6. Nonlinear Pixel Replacement Estimation.

    DTIC Science & Technology

    1986-04-01

    Systems Command _________ _______________________ _____ 6e ADDRESS IC,,, Sra,. and ZIP Co~ de , 10 SOURCE Of FUNDING NUMBERS% RORMELEMENT NO PROJECT NO... de - scribed, this method does not replace array elements with computed values, but rather replaces them with one of the nine original pixel values. The...8217, gmx . NOISE PStd dev=’. sd call exit end include ’mathfunc For/nolist’ C-9 c biweighted 3xZ3 filter compute weighted mean from input iara subroutine

  7. Androgen replacement for women.

    PubMed Central

    Basson, R.

    1999-01-01

    OBJECTIVES: To determine whether a postmenopausal syndrome comprising specific changes in sexual desire and response associated with low free testosterone exists. To determine whether this syndrome is ameliorated by testosterone replacement. QUALITY OF EVIDENCE: Literature documenting that replacement of physiological levels of testosterone is beneficial and safe is scant. Only one randomized prospective blinded study examines sexual outcome in detail. MAIN MESSAGE: Testosterone is an important metabolic and sex hormone produced by the ovary throughout life. The variable reduction in ovarian testosterone production coincident with menopause is sometimes associated with a syndrome of specific changes in sexual desire and sexual response. Estrogen deficiency also impairs sexual response, but its replacement will not improve and might exacerbate sexual symptoms from androgen loss. Diagnosis of androgen deficiency is clinical, based on accurate assessment of a woman's sexual status before and after menopause and only confirmed (rather than diagnosed) by a low level of free testosterone. Partial androgen replacement restores much of the sexual response and facilitates sexual desire that is triggered by external cues. Avoiding supraphysiological levels of testosterone lessens risk of masculinization. Avoiding alkylated testosterone lessens hepatic or lipid impairment. CONCLUSION: Further prospective randomized studies of replacement of physiological levels of testosterone in women with androgen deficiency syndrome are needed, using formulations of testosterone available in Canada. The consistency of sexual changes, the associated personal and relationship distress, together with our clinical experience of the gratifying response to physiological replacement, make further studies urgently needed. PMID:10509222

  8. In-band insertion of RoF LTE Services in OOK based PON's using line coding techniques

    NASA Astrophysics Data System (ADS)

    Saljoghei, Arsalan; Browning, Colm; Barry, Liam P.

    2015-12-01

    We demonstrate the creation of multiple spectral nulls, in a 10 Gb/s On Off Keyed signal with the help of encoders with inherent DC-balanced and minimum-bandwidth properties. Within a hybrid wired/wireless PON architecture, these generated nulls are subsequently used to transmit a wireless signal with 20 MHz of bandwidth carrying Long Term Evolution (LTE) service. The level of interference experienced on both the wired 10 G signal and the wireless signal was studied for various wireless power levels and the encoding order. Results show significant system performance enhancements due to the reduction of interference, which had been achieved by encoding the baseband data signal. Finally numerical simulations are employed to elaborate on performance of the encoded system.

  9. Measure Guideline: Window Repair, Rehabilitation, and Replacement

    SciTech Connect

    Baker, P.

    2012-12-01

    This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

  10. 48 CFR 8.715 - Replacement commodities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Replacement commodities. 8.715 Section 8.715 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition From Nonprofit Agencies Employing People Who...

  11. 40 CFR 1068.240 - What are the provisions for exempting new replacement engines?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... placed into service or remain in inventory. After an engine is placed into service, your report must... engine that is used to replace an engine that has already been placed into service (whether the previous... placed into service in a piece of equipment. (2) The engine being replaced was not originally subject...

  12. Rehab permits desert line to run at original pressures

    SciTech Connect

    Kurdi, A.M.; Abougfeefa, M.S. ); Denney, A.K. )

    1993-07-26

    An extensive inspection and rehabilitation program on a 34-in. desert pipeline in gas-condensate service has restored the line to full operating pressures and ensured the line's active service life for at least 20 years. Since Agip Oil Co. Ltd. built the 133-km pipeline in 1972 using API 5L Grade X-60, it has suffered six known failures. There has been no single cause of the failures. As a consequence of the failures, the line has been progressively down rated from the original operating pressure of 700 psig to 500 psig. So that the line could again be operated between 650 and 700 psig, two options have been considered: extensive study and investigation leading to inspection and replacement of suspect pipe: total replacement of the line. These options were evaluated from economic and safety points of view. A major consideration was that the line will be operating in its current manner for only the next 2 years before changing to dry-gas transportation. The first option was therefore considered viable. The paper discusses the failure mechanisms, the history of hydrogen-induced cracking, the 1989 failure, survey results, calculation of acceptable pressures, and the rehabilitation program.

  13. Navigated unicompartmental knee replacement.

    PubMed

    Jenny, Jean-Yves

    2008-06-01

    Computer-aided systems have been developed recently to improve the precision of implantation of unicompartmental knee replacement (UKR) or total knee replacement. Minimal invasive techniques have been developed to decrease the surgical trauma related to the prosthesis implantation. However, there might be a concern about the potential of minimal invasive techniques for a loss of accuracy. Navigation systems might address this issue. We are currently using routinely a nonimage-based navigation for total knee replacement. We developed a modified system for UKR, suitable for either a conventional or a mini-invasive approach. Navigated implantation of a UKR allowed improving the accuracy of the radiologic implantation. Mini-invasive implantation was effective, but the accuracy may not reach that of the conventional navigated technique and should be still improved. Minimal invasive techniques have to be validated because a loss of accuracy will negatively influence long-term outcomes.

  14. Toxicology of chlorofluorocarbon replacements.

    PubMed Central

    Dekant, W

    1996-01-01

    Chlorofluorocarbons (CFCs) are stable in the atmosphere and may reach the stratosphere. They are cleaved by UV-radiation in the stratosphere to yield chlorine radicals, which are thought to interfere with the catalytic cycle of ozone formation and destruction and deplete stratospheric ozone concentrations. Due to potential adverse health effects of ozone depletion, chlorofluorocarbon replacements with much lower or absent ozone depleting potential are developed. The toxicology of these compounds that represent chlorofluorohydrocarbons (HCFCs) or fluorohydrocarbons (HFCs) has been intensively studied. All compounds investigated (1, 1-dichloro-1-fluoroethane [HCFC-141b], 1,1,1,2-tetrafluoroethane [HFC-134a], pentafluoroethane [HFC-125], 1-chloro- 1,2,2,2-tetrafluoroethane [HCFC-124], and 1,1-dichloro-2,2,2-trifluoroethane [HCFC-123]) show only a low potential for skin and eye irritation. Chronic adverse effects on the liver (HCFC-123) and the testes (HCFC-141b and HCFC-134a), including tumor formation, were observed in long-term inhalation studies in rodents using very high concentrations of these CFC replacements. All CFC replacements are, to varying extents, biotransformed in the organism, mainly by cytochrome P450-catalyzed oxidation of C-H bonds. The formed acyl halides are hydrolyzed to give excretable carboxylic acids; halogenated aldehydes that are formed may be further oxidized to halogenated carboxylic acids or reduced to halogenated alcohols, which are excretory metabolites in urine from rodents exposed experimentally to CFC replacements. The chronic toxicity of the CFC replacements studied is unlikely to be of relevance for humans exposed during production and application of CFC replacements. PMID:8722112

  15. Toxicology of chlorofluorocarbon replacements.

    PubMed

    Dekant, W

    1996-03-01

    Chlorofluorocarbons (CFCs) are stable in the atmosphere and may reach the stratosphere. They are cleaved by UV-radiation in the stratosphere to yield chlorine radicals, which are thought to interfere with the catalytic cycle of ozone formation and destruction and deplete stratospheric ozone concentrations. Due to potential adverse health effects of ozone depletion, chlorofluorocarbon replacements with much lower or absent ozone depleting potential are developed. The toxicology of these compounds that represent chlorofluorohydrocarbons (HCFCs) or fluorohydrocarbons (HFCs) has been intensively studied. All compounds investigated (1, 1-dichloro-1-fluoroethane [HCFC-141b], 1,1,1,2-tetrafluoroethane [HFC-134a], pentafluoroethane [HFC-125], 1-chloro- 1,2,2,2-tetrafluoroethane [HCFC-124], and 1,1-dichloro-2,2,2-trifluoroethane [HCFC-123]) show only a low potential for skin and eye irritation. Chronic adverse effects on the liver (HCFC-123) and the testes (HCFC-141b and HCFC-134a), including tumor formation, were observed in long-term inhalation studies in rodents using very high concentrations of these CFC replacements. All CFC replacements are, to varying extents, biotransformed in the organism, mainly by cytochrome P450-catalyzed oxidation of C-H bonds. The formed acyl halides are hydrolyzed to give excretable carboxylic acids; halogenated aldehydes that are formed may be further oxidized to halogenated carboxylic acids or reduced to halogenated alcohols, which are excretory metabolites in urine from rodents exposed experimentally to CFC replacements. The chronic toxicity of the CFC replacements studied is unlikely to be of relevance for humans exposed during production and application of CFC replacements.

  16. Biological tooth replacement

    PubMed Central

    Sartaj, Rachel; Sharpe, Paul

    2006-01-01

    Teeth develop from a series of reciprocal interactions that take place between epithelium and mesenchyme during development of the mouth that begin early in mammalian embryogenesis. The molecular control of key processes in tooth development such as initiation, morphogenesis and cytodifferentiation are being increasingly better understood, to the point where this information can be used as the basis for approaches to produce biological replacement teeth (BioTeeth). This review outlines the current approaches, ideas and progress towards the production of BioTeeth that could form an alternative method for replacing lost or damaged teeth. PMID:17005022

  17. The service-driven service company.

    PubMed

    Schlesinger, L A; Heskett, J L

    1991-01-01

    For more than 40 years, service companies like McDonald's prospered with organizations designed according to the principles of traditional mass-production manufacturing. Today that model is obsolete. It inevitably degrades the quality of service a company can provide by setting in motion a cycle of failure that produces dissatisfied customers, unhappy employees, high turnover among both--and so lower profits and lower productivity overall. The cycle starts with human resource policies that minimize the contributions frontline workers can make: jobs are designed to be idiot-proof. Technology is used largely for monitoring and control. Pay is poor. Training is minimal. Performance expectations are abysmally low. Today companies like Taco Bell, Dayton Hudson, and ServiceMaster are reversing the cycle of failure by putting workers with customer contact first and designing the business system around them. As a result, they are developing a model that replaces the logic of industrialization with a new service-driven logic. This logic: Values investments in people as much as investments in technology--and sometimes more. Uses technology to support the efforts of workers on the front lines, not just to monitor or replace them. Makes recruitment and training crucial for everyone. Links compensation to performance for employees at every level. To justify these investments, the new logic draws on innovative data such as the incremental profits of loyal customers and the total costs of lost employees. Its benefits are becoming clear in higher profits and higher pay--results that competitors bound to the old industrial model will not be able to match.

  18. Cost-effectiveness of Pazopanib Versus Sunitinib as First-line Treatment for Locally Advanced or Metastatic Renal Cell Carcinoma from an Italian National Health Service Perspective.

    PubMed

    Capri, Stefano; Porta, Camillo; Delea, Thomas E

    2017-03-01

    A prior randomized controlled trial (COMPARZ [Comparing the Efficacy, Safety and Tolerability of Pazopanib versus Sunitinib]) found non-inferior progression-free survival for pazopanib versus sunitinib as first-line therapy in patients with advanced or metastatic renal cell carcinoma. The present study evaluated the cost-effectiveness of pazopanib versus sunitinib as first-line treatment for patients with metastatic renal cell carcinoma from an Italian National Health Service perspective. A partitioned-survival analysis model with 3 health states (progression-free survival, post-progression survival, and dead) was employed. The model time horizon was 5 years. For each treatment strategy, the model generated expected progression-free life years, post-progression life years, overall life years, quality-adjusted life years (QALYs), and costs. Results were reported as incremental costs per QALY gained and the net monetary benefit of pazopanib versus sunitinib. Probabilistic and deterministic sensitivity analyses were conducted to assess the impact on results of methodological and parameter uncertainty. In the base case, pazopanib was associated with higher QALYs and lower costs and dominated sunitinib. Using willingness-to-pay thresholds of €30,000 and €50,000 per QALY, the net monetary benefits with pazopanib were €6508 and €7702 per patient, respectively, versus sunitinib. The probability that pazopanib is cost-effective versus sunitinib was estimated to be 85% at a cost-effectiveness threshold of €20,000, 86% at a threshold of €30,000, and 81% at a threshold of €50,000 per QALY. Results were robust to changes in key parameter values and assumptions. These results suggest that pazopanib is likely to represent a cost-effective treatment option compared with sunitinib as first-line treatment for patients with metastatic renal cell carcinoma in Italy. Copyright © 2017. Published by Elsevier Inc.

  19. Hip Resurfacing: An Alternative to Conventional Hip Replacement?

    MedlinePlus

    ... bone is reshaped and capped with a metal prosthesis. The hip socket is fitted with a metal ... but higher levels may be problematic. The socket prosthesis for a traditional hip replacement is usually lined ...

  20. 75 FR 3486 - Susquehanna to Roseland 500kV Transmission Line, Environmental Impact Statement, Delaware Water...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... Pennsylvania Power and Light Electric Utilities (PPL) and Public Service Electric and Gas Company (PSE&G), and... single 230 kV power line and towers currently on the right-of-way would be removed and replaced with... the grid at the direction of the Regional Transmission Operator, PJM Interconnection (PJM)....

  1. Window Replacement Tips.

    ERIC Educational Resources Information Center

    Wiens, Janet

    2001-01-01

    Explores ways to replace facility windows more easily and efficiently by evaluating long-term needs and window options. Recommends obtaining references from window manufacturer and installer, scheduling the work during times the facility is unoccupied, and ensuring that historic and life-safety issues be considered. (GR)

  2. Python import replacement

    SciTech Connect

    2011-10-01

    SmartImport.py is a Python source-code file that implements a replacement for the standard Python module importer. The code is derived from knee.py, a file in the standard Python diestribution , and adds functionality to improve the performance of Python module imports in massively parallel contexts.

  3. Hexachloroethane Obscurant Replacement

    DTIC Science & Technology

    2012-01-01

    suggest that neither the alkali metal hydroxides nor chlorides are extremely toxic (11). Oral rat LD50 values are indeed lower for hydroxide salts...analyze for toxicity of combustion gases and particulates. Compositions containing boron potassium nitrate igniter blended with halide salts...variants were identified which should have improved performance. 15. SUBJECT TERMS Non- toxic obscurant, hexachloroethane smoke replacement 16

  4. Python import replacement

    SciTech Connect

    2011-10-01

    SmartImport.py is a Python source-code file that implements a replacement for the standard Python module importer. The code is derived from knee.py, a file in the standard Python diestribution , and adds functionality to improve the performance of Python module imports in massively parallel contexts.

  5. Replacing America's Job Bank

    ERIC Educational Resources Information Center

    Vollman, Jim

    2009-01-01

    The Job Central National Labor Exchange (www.jobcentral.com) has become the effective replacement for America's Job Bank with state workforce agencies and, increasingly, with community colleges throughout the country. The American Association of Community Colleges (AACC) has formed a partnership with Job Central to promote its use throughout the…

  6. Replacing America's Job Bank

    ERIC Educational Resources Information Center

    Vollman, Jim

    2009-01-01

    The Job Central National Labor Exchange (www.jobcentral.com) has become the effective replacement for America's Job Bank with state workforce agencies and, increasingly, with community colleges throughout the country. The American Association of Community Colleges (AACC) has formed a partnership with Job Central to promote its use throughout the…

  7. Valve assembly having remotely replaceable bearings

    DOEpatents

    Johnson, Evan R.; Tanner, David E.

    1980-01-01

    A valve assembly having remotely replaceable bearings is disclosed wherein a valve disc is supported within a flow duct for rotation about a pair of axially aligned bearings, one of which is carried by a spindle received within a diametral bore in the valve disc, and the other of which is carried by a bearing support block releasably mounted on the duct circumferentially of an annular collar on the valve disc coaxial with its diametrical bore. The spindle and bearing support block are adapted for remote removal to facilitate servicing or replacement of the valve disc support bearings.

  8. Evolution of high tooth replacement rates in sauropod dinosaurs.

    PubMed

    D'Emic, Michael D; Whitlock, John A; Smith, Kathlyn M; Fisher, Daniel C; Wilson, Jeffrey A

    2013-01-01

    Tooth replacement rate can be calculated in extinct animals by counting incremental lines of deposition in tooth dentin. Calculating this rate in several taxa allows for the study of the evolution of tooth replacement rate. Sauropod dinosaurs, the largest terrestrial animals that ever evolved, exhibited a diversity of tooth sizes and shapes, but little is known about their tooth replacement rates. We present tooth replacement rate, formation time, crown volume, total dentition volume, and enamel thickness for two coexisting but distantly related and morphologically disparate sauropod dinosaurs Camarasaurus and Diplodocus. Individual tooth formation time was determined by counting daily incremental lines in dentin. Tooth replacement rate is calculated as the difference between the number of days recorded in successive replacement teeth. Each tooth family in Camarasaurus has a maximum of three replacement teeth, whereas each Diplodocus tooth family has up to five. Tooth formation times are about 1.7 times longer in Camarasaurus than in Diplodocus (315 vs. 185 days). Average tooth replacement rate in Camarasaurus is about one tooth every 62 days versus about one tooth every 35 days in Diplodocus. Despite slower tooth replacement rates in Camarasaurus, the volumetric rate of Camarasaurus tooth replacement is 10 times faster than in Diplodocus because of its substantially greater tooth volumes. A novel method to estimate replacement rate was developed and applied to several other sauropodomorphs that we were not able to thin section. Differences in tooth replacement rate among sauropodomorphs likely reflect disparate feeding strategies and/or food choices, which would have facilitated the coexistence of these gigantic herbivores in one ecosystem. Early neosauropods are characterized by high tooth replacement rates (despite their large tooth size), and derived titanosaurs and diplodocoids independently evolved the highest known tooth replacement rates among archosaurs.

  9. Evolution of High Tooth Replacement Rates in Sauropod Dinosaurs

    PubMed Central

    Smith, Kathlyn M.; Fisher, Daniel C.; Wilson, Jeffrey A.

    2013-01-01

    Background Tooth replacement rate can be calculated in extinct animals by counting incremental lines of deposition in tooth dentin. Calculating this rate in several taxa allows for the study of the evolution of tooth replacement rate. Sauropod dinosaurs, the largest terrestrial animals that ever evolved, exhibited a diversity of tooth sizes and shapes, but little is known about their tooth replacement rates. Methodology/Principal Findings We present tooth replacement rate, formation time, crown volume, total dentition volume, and enamel thickness for two coexisting but distantly related and morphologically disparate sauropod dinosaurs Camarasaurus and Diplodocus. Individual tooth formation time was determined by counting daily incremental lines in dentin. Tooth replacement rate is calculated as the difference between the number of days recorded in successive replacement teeth. Each tooth family in Camarasaurus has a maximum of three replacement teeth, whereas each Diplodocus tooth family has up to five. Tooth formation times are about 1.7 times longer in Camarasaurus than in Diplodocus (315 vs. 185 days). Average tooth replacement rate in Camarasaurus is about one tooth every 62 days versus about one tooth every 35 days in Diplodocus. Despite slower tooth replacement rates in Camarasaurus, the volumetric rate of Camarasaurus tooth replacement is 10 times faster than in Diplodocus because of its substantially greater tooth volumes. A novel method to estimate replacement rate was developed and applied to several other sauropodomorphs that we were not able to thin section. Conclusions/Significance Differences in tooth replacement rate among sauropodomorphs likely reflect disparate feeding strategies and/or food choices, which would have facilitated the coexistence of these gigantic herbivores in one ecosystem. Early neosauropods are characterized by high tooth replacement rates (despite their large tooth size), and derived titanosaurs and diplodocoids independently

  10. 7 CFR 4280.138 - Replacement of document.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Replacement of document. 4280.138 Section 4280.138 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND... Efficiency Improvements Program Section B. Guaranteed Loans § 4280.138 Replacement of document....

  11. 2. BARN. VIEW LOOKING NORTHWEST. THE ROLLING DOOR PROBABLY REPLACES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. BARN. VIEW LOOKING NORTHWEST. THE ROLLING DOOR PROBABLY REPLACES AN ORIGINAL 4/4 DOUBLE-HUNG WINDOW. - Tonto Ranger Station, Barn, Forest Service Road 65 at Tonto Wash, Skull Valley, Yavapai County, AZ

  12. 36 CFR 72.41 - Demolition and replacement of existing recreation properties.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SERVICE, DEPARTMENT OF THE INTERIOR URBAN PARK AND RECREATION RECOVERY ACT OF 1978 Grants for Recovery... replacement. The applicant must present a cost analysis (well documented case) for demolition and replacement...

  13. 36 CFR 72.41 - Demolition and replacement of existing recreation properties.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SERVICE, DEPARTMENT OF THE INTERIOR URBAN PARK AND RECREATION RECOVERY ACT OF 1978 Grants for Recovery... replacement. The applicant must present a cost analysis (well documented case) for demolition and replacement...

  14. Celotex (Registered) Replacement Study

    SciTech Connect

    Couture, S; Hafner, R

    2002-10-01

    The AL-R8 is the pit storage container in most widespread use at Pantex. The AL-R8 container family consists of standard 20-in.-diameter steel drums, 30 to 60 in. in height, with insulation inserts made of Celotex{reg_sign}--a fiberboard product made from processed sugar cane. Celotex is an acceptable material for inserts in many radioactive material shipping and storage containers. It is a good shock mitigator/insulator, does a fair job in fire protection (when oxygen is excluded), shielding, and criticality, and is inexpensive and easily available. However, the fiberboard absorbs water in humid environments which, when combined with chemical residues in the fiberboard, forms corrosive compounds that can shorten the life of the container and affect container contents. To protect the contents from this potentially damaging environment, the AL-R8 SI was developed to isolate the contents within a sealed stainless steel vessel inside the AL-R8. Although the SI protected the contents, corrosion studies indicated the SI lid bolts might corrode over time and surveillance showed that areas of the outer drum were still subject to corrosion. To address this potential problem, DOE/Albuquerque sponsored bolt and Celotex replacement studies. The bolt replacement study was assigned to Mason and Hanger's Pantex Facility and this Celotex Replacement Study to Lawrence Livermore National Laboratory. The Celotex Replacement Study evaluated options for replacing Celotex with a material that is chemically compatible with the AL-R8 SI container. The evaluation was limited to materials either used previously in nuclear materials shipping and storage containers or materials with known properties in a low-radiation environment. This limitation was set to ensure that the long-term aging effect on the new material is known a priori. Initial material evaluations narrowed the material choices to foam and cork. Although cork performed better than foam in some tests, cork was considered a less

  15. NARC Rayon Replacement Program

    NASA Technical Reports Server (NTRS)

    Wilson, Kenneth P.; McCool, Alex (Technical Monitor)

    2002-01-01

    This viewgraph presentation provides information on the search for a replacement product for the aerospace grade rayon formerly used in the reusable solid rocket motor (RSRM). The rayon used in RSRMs is no longer produced by the North American Rayon Corporation (NARC), though NASA has stockpiled rayon to be used until a suitable replacement is found to be used in the RSRM nozzle carbon cloth phenolic (CCP). The primary considerations are performance, process ability, variability, long term availability, and cost. The preference will be given to commercial off-the-shelf products as opposed to those which are custom made. The candidate materials have been tested in previous phases of this selection process, and Enka Textile Rayon has emerged as a possible fabric, though its availability is still in question.

  16. Ulnar head replacement.

    PubMed

    Herbert, Timothy J; van Schoonhoven, Joerg

    2007-03-01

    Recent years have seen an increasing awareness of the anatomical and biomechanical significance of the distal radioulnar joint (DRUJ). With this has come a more critical approach to surgical management of DRUJ disorders and a realization that all forms of "excision arthroplasty" can only restore forearm rotation at the expense of forearm stability. This, in turn, has led to renewed interest in prosthetic replacement of the ulnar head, a procedure that had previously fallen into disrepute because of material failures with early implants, in particular, the Swanson silicone ulnar head replacement. In response to these early failures, a new prosthesis was developed in the early 1990s, using materials designed to withstand the loads across the DRUJ associated with normal functional use of the upper limb. Released onto the market in 1995 (Herbert ulnar head prosthesis), clinical experience during the last 10 years has shown that this prosthesis is able to restore forearm function after ulnar head excision and that the materials (ceramic head and noncemented titanium stem), even with normal use of the limb, are showing no signs of failure in the medium to long term. As experience with the use of an ulnar head prosthesis grows, so does its acceptance as a viable and attractive alternative to more traditional operations, such as the Darrach and Sauve-Kapandji procedures. This article discusses the current indications and contraindications for ulnar head replacement and details the surgical procedure, rehabilitation, and likely outcomes.

  17. Renal Replacement Therapy

    PubMed Central

    Ricci, Zaccaria; Romagnoli, Stefano; Ronco, Claudio

    2016-01-01

    During the last few years, due to medical and surgical evolution, patients with increasingly severe diseases causing multiorgan dysfunction are frequently admitted to intensive care units. Therapeutic options, when organ failure occurs, are frequently nonspecific and mostly directed towards supporting vital function. In these scenarios, the kidneys are almost always involved and, therefore, renal replacement therapies have become a common routine practice in critically ill patients with acute kidney injury. Recent technological improvement has led to the production of safe, versatile and efficient dialysis machines. In addition, emerging evidence may allow better individualization of treatment with tailored prescription depending on the patients’ clinical picture (e.g. sepsis, fluid overload, pediatric). The aim of the present review is to give a general overview of current practice in renal replacement therapies for critically ill patients. The main clinical aspects, including dose prescription, modality of dialysis delivery, anticoagulation strategies and timing will be addressed. In addition, some technical issues on physical principles governing blood purification, filters characteristics, and vascular access, will be covered. Finally, a section on current standard nomenclature of renal replacement therapy is devoted to clarify the “Tower of Babel” of critical care nephrology. PMID:26918174

  18. Replacement steel windows

    SciTech Connect

    Brown, M.A.; Condren, S.J.

    1999-07-01

    This paper presents the authors experiences in the investigation, design, and installation of replacement steel windows for two renovation projects at a major university in the northeast: a student residential complex and the law school. The authors review the construction of the existing walls (cast-in-place concrete barrier wall at the student residential complex and brick and stone masonry barrier wall at the law school), and the construction and performance of the original steel windows. To maintain the appearance of these architecturally significant buildings, the university elected to install replacement steel windows. The authors discuss special design consideration for steel windows (versus the more prevalent aluminum replacement window), including available window section profiles, corrosion protection, frame fabrication, and glazing design. The authors also review window flashing concepts they employed for the barrier wall construction, which has no drainage cavity. The authors summarize lessons learned during the window selection, design, fabrication, testing, and installation phases of the projects, and present recommendations for improved durability and water penetration resistance of steel windows.

  19. Object replacement using dynamic proxy updates

    NASA Astrophysics Data System (ADS)

    Menon, S.; LeBlanc, R. J., Jr.

    1994-09-01

    In a distributed environment, a client program bound to a server fails when the server changes (possibly due to the server being relocated, replicated or reconfigured). In this paper, we describe the design of an object-replacement scheme in a client-server environment. Our design addresses the problem of replacing a server and transparently updating the client handle so that no service interruption is experienced by the client. The programming environment, on which this work is based, provides passive shared objects, threads, and invocations as the building blocks for distributed applications. Our design takes into account the potential concurrency within clients and servers. Our task was relatively simplified by building the replacement mechanisms on top of an asynchronous event notification facility that handles events on a per-application basis, as opposed to a per-task or per-thread basis.

  20. A Quantitative Risk Assessment Model Involving Frequency and Threat Degree under Line-of-Business Services for Infrastructure of Emerging Sensor Networks.

    PubMed

    Jing, Xu; Hu, Hanwen; Yang, Huijun; Au, Man Ho; Li, Shuqin; Xiong, Naixue; Imran, Muhammad; Vasilakos, Athanasios V

    2017-03-21

    The prospect of Line-of-Business Services (LoBSs) for infrastructure of Emerging Sensor Networks (ESNs) is exciting. Access control remains a top challenge in this scenario as the service provider's server contains a lot of valuable resources. LoBSs' users are very diverse as they may come from a wide range of locations with vastly different characteristics. Cost of joining could be low and in many cases, intruders are eligible users conducting malicious actions. As a result, user access should be adjusted dynamically. Assessing LoBSs' risk dynamically based on both frequency and threat degree of malicious operations is therefore necessary. In this paper, we proposed a Quantitative Risk Assessment Model (QRAM) involving frequency and threat degree based on value at risk. To quantify the threat degree as an elementary intrusion effort, we amend the influence coefficient of risk indexes in the network security situation assessment model. To quantify threat frequency as intrusion trace effort, we make use of multiple behavior information fusion. Under the influence of intrusion trace, we adapt the historical simulation method of value at risk to dynamically access LoBSs' risk. Simulation based on existing data is used to select appropriate parameters for QRAM. Our simulation results show that the duration influence on elementary intrusion effort is reasonable when the normalized parameter is 1000. Likewise, the time window of intrusion trace and the weight between objective risk and subjective risk can be set to 10 s and 0.5, respectively. While our focus is to develop QRAM for assessing the risk of LoBSs for infrastructure of ESNs dynamically involving frequency and threat degree, we believe it is also appropriate for other scenarios in cloud computing.

  1. A Quantitative Risk Assessment Model Involving Frequency and Threat Degree under Line-of-Business Services for Infrastructure of Emerging Sensor Networks

    PubMed Central

    Jing, Xu; Hu, Hanwen; Yang, Huijun; Au, Man Ho; Li, Shuqin; Xiong, Naixue; Imran, Muhammad; Vasilakos, Athanasios V.

    2017-01-01

    The prospect of Line-of-Business Services (LoBSs) for infrastructure of Emerging Sensor Networks (ESNs) is exciting. Access control remains a top challenge in this scenario as the service provider’s server contains a lot of valuable resources. LoBSs’ users are very diverse as they may come from a wide range of locations with vastly different characteristics. Cost of joining could be low and in many cases, intruders are eligible users conducting malicious actions. As a result, user access should be adjusted dynamically. Assessing LoBSs’ risk dynamically based on both frequency and threat degree of malicious operations is therefore necessary. In this paper, we proposed a Quantitative Risk Assessment Model (QRAM) involving frequency and threat degree based on value at risk. To quantify the threat degree as an elementary intrusion effort, we amend the influence coefficient of risk indexes in the network security situation assessment model. To quantify threat frequency as intrusion trace effort, we make use of multiple behavior information fusion. Under the influence of intrusion trace, we adapt the historical simulation method of value at risk to dynamically access LoBSs’ risk. Simulation based on existing data is used to select appropriate parameters for QRAM. Our simulation results show that the duration influence on elementary intrusion effort is reasonable when the normalized parameter is 1000. Likewise, the time window of intrusion trace and the weight between objective risk and subjective risk can be set to 10 s and 0.5, respectively. While our focus is to develop QRAM for assessing the risk of LoBSs for infrastructure of ESNs dynamically involving frequency and threat degree, we believe it is also appropriate for other scenarios in cloud computing. PMID:28335569

  2. Total hip and total knee replacement: preoperative nursing management.

    PubMed

    Lucas, Brian

    Total hip replacement (THR) and total knee replacement (TKR) surgery are carried out for the relief of hip or knee pain, usually caused by osteoarthritis. This is the first of two articles on THR and TKR. It will outline the different types of replacement used in lower limb joint replacement surgery. Preparation of patients for surgery requires attention to physical, psychological and social factors and these are explored in detail. The organization of services along the patient pathway to ensure comprehensive preparation is considered and the nursing role highlighted. The second article, to be published in the next issue, will discuss recovery and rehabilitation from THR and TKR surgery.

  3. Why women bypass front-line health facility services in pursuit of obstetric care provided elsewhere: a case study in three rural districts of Tanzania.

    PubMed

    Kanté, A M; Exavery, A; Phillips, J F; Jackson, E F

    2016-04-01

    In the Tanzanian health system, women are expected to first visit their nearest front-line health facility (FLF) for delivery. However, women frequently bypass these FLF. Our study estimates the extent of bypassing for childbirth and assesses factors associated with this behaviour. Data describing the experiences of 597 women who recently delivered at a facility and the EmONC service capability at 107 health facilities were collected in 2011. Women who did not deliver at their nearest FLF were considered 'bypassers'. Factors associated with bypassing were assessed using multivariate logistic regression models. Three sets of analyses were conducted: among 597 women who delivered at the first facility they visited, among 521 women with no previous complications, and among 407 women not primigravida and without previous complications. More than 75.4% of women bypassed. In the fully adjusted model of all 597 women those who had experienced complications were more likely to bypass for delivery [OR = 6.31 (2.36, 16.86)]. In the fully adjusted model excluding women with previous complications, primigravida women were more likely to bypass [OR = 3.70 (1.71, 8.01)]. Fully adjusted models for each set of analysis found that, for each additional emergency obstetric and newborn care signal function (EmONC SF) available at the nearest FLF, women's odds of bypassing almost halved. Bypassing is highly associated with EmONC SF score at nearest FLF, controlling for individual and community-level factors. © 2016 John Wiley & Sons Ltd.

  4. Partial knee replacement - slideshow

    MedlinePlus

    ... in joints to provide shock absorption during movement. Review Date 7/13/2015 Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic ...

  5. Aircraft Ground Operation, Servicing, Fluid Lines and Fittings, Mechanics Privileges and Limitations, and Maintenance Publications, Forms and Records (Course Outline), Aviation Mechanics 1 (Power and Frame): 9073.02.

    ERIC Educational Resources Information Center

    Dade County Public Schools, Miami, FL.

    The course outline consists of five instructional blocks of several units each: (1) Aircraft Ground Operation and Servicing; (2) Fluid Lines and Fittings; (3) Mechanics Requirements, Privileges and Limitations; (4) Maintenance Publications; and, (5) Maintenance forms and Records. It is a basic course of knowledge and skills necessary to any…

  6. Report to the Legislature on: School Breakfast and Summer Food Service Programs. MGL Chapter 15 Section 1G(f) and Chapter 61 of the Acts of 2007 Line Item 7053-1925

    ERIC Educational Resources Information Center

    Massachusetts Department of Education, 2008

    2008-01-01

    The paper presents the report on "School Breakfast and Summer Food Service Program." Pursuant to Chapter 61 of the Acts of 2007 line item 7053-1925 and Massachusetts General Laws (MGL) chapter 15 section 1G(f), this report is submitted to the Legislature. An Act establishing school-based Nutrition and Child Hunger Relief Programs was…

  7. Total ankle joint replacement.

    PubMed

    2016-02-01

    Ankle arthritis results in a stiff and painful ankle and can be a major cause of disability. For people with end-stage ankle arthritis, arthrodesis (ankle fusion) is effective at reducing pain in the shorter term, but results in a fixed joint, and over time the loss of mobility places stress on other joints in the foot that may lead to arthritis, pain and dysfunction. Another option is to perform a total ankle joint replacement, with the aim of giving the patient a mobile and pain-free ankle. In this article we review the efficacy of this procedure, including how it compares to ankle arthrodesis, and consider the indications and complications.

  8. Immediate total tooth replacement.

    PubMed

    Garber, D A; Salama, M A; Salama, H

    2001-03-01

    Successful implant placement at the time of extraction has been documented. Implant placement at the time of extraction was initially performed as a two-stage procedure often with barrier membranes and sophisticated second-stage surgical uncoverings. The authors describe the next generation of this technique, including atraumatic tooth removal with simultaneous root form, implant placement, and temporization at one appointment. This technique of "Immediate Total Tooth Replacement" allows for the maintenance of the bony housing and soft-tissue form that existed before extraction, while at the same time establishing a root form anchor in the bone for an esthetic restoration.

  9. [Hormone replacement therapy].

    PubMed

    Nozue, E

    1994-03-01

    Hormone replacement therapy after menopause has shown so many advantages, such as reduction in risk of coronary artery disease and osteoporotic fracture besides treatment for climacteric symptoms, yet disadvantage such as a probability of an increase in the risk of breast cancer with long-term use still remains. In Japan HRT is now at the starting point. We must try to make more effort to accumulate data on the safety of HRT during-and-after menopause. It is our hope that doctors, not only gynecologists, but also doctors of other specialties will join our program for the health and happiness of women after menopause.

  10. Distribution main rehabilitated with HDPE lining process

    SciTech Connect

    Ruiz, M. )

    1994-08-01

    Innovative use of a new HDPE lining technology recently saved Brooklyn Union Gas Co. 30% over conventional replacement costs. The company chose lining technology from United Pipeline Systems called Tite Liner to rehabilitate 2,500 ft of 20-in., 15 psig, bare steel main in Brooklyn's Bay Ridge section, an area spanning six city blocks and crossing three major avenues. The main is mechanically joined with no offsets or service connections. Due to surface and subsurface working space restrictions and the impact on costs, the company elected to employ the liner system in which a specially designed HDPE liner pipe is reduced to a smaller diameter through a rolldown box for insertion into a steel or cast iron main. A tight fit is attained as the liner is allowed to expand against the pipe wall after pull through.

  11. Prosthesis-preserving aortic root repair after aortic valve replacement.

    PubMed

    Hamamoto, Masaki; Kobayashi, Taira; Kodama, Hiroshi

    2015-07-01

    We describe a new technique of prosthesis-preserving aortic root replacement for patients who have previously undergone aortic valve replacement. With preservation of the mechanical prosthesis, we implant a Gelweave Valsalva graft using double suture lines. The first suture line is made between the sewing cuff of the mechanical valve and the graft, with mattress sutures of 2/0 braided polyester with pledgets. After the first sutures are tied, the second suture line is created between the graft collar and the aortic root remnant with continuous 4/0 polypropylene sutures.

  12. Cadmium plating replacements

    NASA Technical Reports Server (NTRS)

    Nelson, Mary J.; Groshart, Earl C.

    1995-01-01

    The Boeing Company has been searching for replacements to cadmium plate. Two alloy plating systems seem close to meeting the needs of a cadmium replacement. The two alloys, zinc-nickel and tin-zinc are from alloy plating baths; both baths are neutral pH. The alloys meet the requirements for salt fog corrosion resistance, and both alloys excel as a paint base. Currently, tests are being performed on standard fasteners to compare zinc-nickel and tin-zinc on threaded hardware where cadmium is heavily used. The Hydrogen embrittlement propensity of the zinc-nickel bath has been tested, and just beginning for the tin-zinc bath. Another area of interest is the electrical properties on aluminum for tin-zinc and will be discussed. The zinc-nickel alloy plating bath is in production in Boeing Commercial Airplane Group for non-critical low strength steels. The outlook is promising that these two coatings will help The Boeing Company significantly reduce its dependence on cadmium plating.

  13. Sutureless aortic valve replacement

    PubMed Central

    Phan, Kevin

    2015-01-01

    The increasing incidence of aortic stenosis and greater co-morbidities and risk profiles of the contemporary patient population has driven the development of minimally invasive aortic valve surgery and percutaneous transcatheter aortic valve implantation (TAVI) techniques to reduce surgical trauma. Recent technological developments have led to an alternative minimally invasive option which avoids the placement and tying of sutures, known as “sutureless” or rapid deployment aortic valves. Potential advantages for sutureless aortic prostheses include reducing cross-clamp and cardiopulmonary bypass (CPB) duration, facilitating minimally invasive surgery and complex cardiac interventions, whilst maintaining satisfactory hemodynamic outcomes and low paravalvular leak rates. However, given its recent developments, the majority of evidence regarding sutureless aortic valve replacement (SU-AVR) is limited to observational studies and there is a paucity of adequately-powered randomized studies. Recently, the International Valvular Surgery Study Group (IVSSG) has formulated to conduct the Sutureless Projects, set to be the largest international collaborative group to investigate this technology. This keynote lecture will overview the use, the potential advantages, the caveats, and current evidence of sutureless and rapid deployment aortic valve replacement (AVR). PMID:25870807

  14. Cadmium plating replacements

    SciTech Connect

    Nelson, M.J.; Groshart, E.C.

    1995-03-01

    The Boeing Company has been searching for replacements to cadmium plate. Two alloy plating systems seem close to meeting the needs of a cadmium replacement. The two alloys, zinc-nickel and tin-zinc are from alloy plating baths; both baths are neutral pH. The alloys meet the requirements for salt fog corrosion resistance, and both alloys excel as a paint base. Currently, tests are being performed on standard fasteners to compare zinc-nickel and tin-zinc on threaded hardware where cadmium is heavily used. The Hydrogen embrittlement propensity of the zinc-nickel bath has been tested, and just beginning for the tin-zinc bath. Another area of interest is the electrical properties on aluminum for tin-zinc and will be discussed. The zinc-nickel alloy plating bath is in production in Boeing Commercial Airplane Group for non-critical low strength steels. The outlook is promising that these two coatings will help The Boeing Company significantly reduce its dependence on cadmium plating.

  15. Total disc replacement.

    PubMed

    Vital, J-M; Boissière, L

    2014-02-01

    Total disc replacement (TDR) (partial disc replacement will not be described) has been used in the lumbar spine since the 1980s, and more recently in the cervical spine. Although the biomechanical concepts are the same and both are inserted through an anterior approach, lumbar TDR is conventionally indicated for chronic low back pain, whereas cervical TDR is used for soft discal hernia resulting in cervicobrachial neuralgia. The insertion technique must be rigorous, with precise centering in the disc space, taking account of vascular anatomy, which is more complex in the lumbar region, particularly proximally to L5-S1. All of the numerous studies, including prospective randomized comparative trials, have demonstrated non-inferiority to fusion, or even short-term superiority regarding speed of improvement. The main implant-related complication is bridging heterotopic ossification with resulting loss of range of motion and increased rates of adjacent segment degeneration, although with an incidence lower than after arthrodesis. A sufficiently long follow-up, which has not yet been reached, will be necessary to establish definitively an advantage for TDR, particularly in the cervical spine. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  16. Big George to Carter Mountain 115-kV transmission line project, Park and Hot Springs Counties, Wyoming. Environmental Assessment

    SciTech Connect

    Not Available

    1994-02-01

    The Western Area Power Administration (Western) is proposing to rebuild, operate, and maintain a 115-kilovolt (kV) transmission line between the Big George and Carter Mountain Substations in northwest Wyoming (Park and Hot Springs Counties). This environmental assessment (EA) was prepared in compliance with the National Environmental Policy Act (NEPA) and the regulations of the Council on Environmental Quality (CEQ) and the Department of Energy (DOE). The existing Big George to Carter Mountain 69-kV transmission line was constructed in 1941 by the US Department of Interior, Bureau of Reclamation, with 1/0 copper conductor on wood-pole H-frame structures without an overhead ground wire. The line should be replaced because of the deteriorated condition of the wood-pole H-frame structures. Because the line lacks an overhead ground wire, it is subject to numerous outages caused by lightning. The line will be 54 years old in 1995, which is the target date for line replacement. The normal service life of a wood-pole line is 45 years. Under the No Action Alternative, no new transmission lines would be built in the project area. The existing 69-kV transmission line would continue to operate with routine maintenance, with no provisions made for replacement.

  17. Hormone replacement therapy and longevity.

    PubMed

    Comhaire, F

    2016-02-01

    To assess whether hormone replacement therapy influences longevity, an analysis was made of published life tables allowing for the calculation of the relative benefit of hormone replacement therapy on longevity in men with late onset hypogonadism and in post-menopausal women. It was found that testosterone replacement therapy of men suffering from late onset hypogonadism increased survival rate by 9-10% in 5 years, similar to that of eugonadal, non-LOH men with normal endogenous testosterone secretion. Oestrogen replacement therapy resulted in increased survival by 2.6% in 5 years. It is concluded that hormone replacement therapy increases longevity.

  18. Functional replacements for gluten.

    PubMed

    Zannini, Emanuele; Jones, Julie Miller; Renzetti, Stefano; Arendt, Elke K

    2012-01-01

    Celiac disease (CD) is an immune-mediated disease triggered in genetically susceptible individuals by ingested gluten from wheat, rye, barley, and other closely related cereal grains. Currently, the only therapy able to normalize the clinical and histological manifestation of the disease is a strict and life-long gluten-free (GF) diet. The replacement of gluten presents a significant technological challenge, as it is an essential structure-building protein, which is necessary for formulating high-quality baked goods. The objective of this paper is to review some basics about CD, its current prevalence, and the recent advances in the preparation of high-quality GF breads using GF flours, starches, hydrocolloids, gums, and novel functional ingredients and technologies.

  19. Antenna grout replacement system

    NASA Technical Reports Server (NTRS)

    Mcclung, C. E. (Inventor)

    1983-01-01

    An epoxy grout suitable for use in mounting and positioning bearing runner plates used in hydrostatic bearing assemblies for rotatably mounting large radio telescope structures to stationary support pedestals is described. The epoxy grout may be used in original mountings or may be used as part of a replacement system for repairing cavities in existing grout resulting from grout deterioration. The epoxy grout has a relatively short work life and cure time even in the presence of hydraulic oil. The epoxy grout cures without shrinking or sagging to form a grout which is sufficiently strong and durable to provide a grout especially well suited for use under the high pressure loading and close tolerance requirements of large hydrostatic bearing assemblies.

  20. Qualities and Practices of Professional Social Work Leadership in an Interdisciplinary Mental Health Service: An Action Learning Approach

    ERIC Educational Resources Information Center

    McNabb, David; Webster, Michael

    2010-01-01

    Since the mid-1980s, health service restructuring in New Zealand has strengthened managerialism, arguably detracting from professional considerations. Professional leaders without line-management responsibilities have replaced social work departments headed by a professional social worker. An emerging social work contribution to interdisciplinary…

  1. A minority research and education information service: Design, develop, pilot test, and implement on-line access for historically black colleges and universities and government agencies. Annual status report, April 1, 1991--March 31, 1992

    SciTech Connect

    Rodman, J.A.

    1992-06-01

    This Annual Status Report describes the design, development and implementation of the Minority On-Line Information Service (MOLIS) project by Federal Information Exchange, Inc. for the period of April 1, 1991 to March 31, 1992. Summary information detailing developments prior to this reporting period will also be included to establish a comprehensive perspective of the project. The goal of the MOLIS project, was to develop, design, pilot test on-line access to current information on minority colleges and universities and federal minority opportunities. Federal Information Exchange, Inc. (FIE), a diversified information services company recognized by researchers and educators as a leader in the field of information delivery services, was awarded a 5 year small business research grant to develop and implement MOLIS. Since April 29, 1991, the inauguration of its on-line service, MOLIS has provided current information on 138 Black and Hispanic colleges and universities -- including faculty and student profiles, financial data, research centers and equipment information, pre-college and education programs, emerging capabilities, enrollment data, administrative personnel data, and current events -- as well as minority opportunities from 8 participating federal agencies.

  2. Aspects of Information Service Management. Proceedings of the Fall Meeting of the New England On-Line Users Group (Tufts University, November 3, 1978).

    ERIC Educational Resources Information Center

    New England On-Line Users Group.

    The proceedings of this meeting on online service administration comprise the three papers presented: one written by Helen G. Drinan concerning costing and budgeting for online information services; one by Robert McDermand on marketing, publicizing, and other service aspects of online searching; and one by Donna R. Dolan pertaining to the training…

  3. Steam-generator replacement sets new marks

    SciTech Connect

    Beck, R.L.

    1995-04-01

    This article describes how, in one of the most successful steam-generator replacement experiences at PWRs worldwide, the V C Summer retrofit exceeded plant goals for critical-path duration, radiation, exposure, and radwaste generation. Intensive planning and teamwork, combined with the firm support of station management and the use of mockups to prepare the work crews for activity in a radiological environment, were key factors in the record performance achieved by South Carolina Electric and Gas Co (SCE and G) in replacing three steam generators at V C Summer nuclear station. The 97-day, two-hour breaker-to-breaker replacement outage -- including an eight-day delay for repair of leak in a small-bore seal-injection line of a reactor coolant pump (unrelated to the replacement activities) -- surpassed the project goal by over one day. Moreover, the outage was only 13 hours shy of the world record held by Virginia Power Co`s North Anna Unit 1.

  4. 49 CFR 551.49 - May a foreign manufacturer replace its agent?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false May a foreign manufacturer replace its agent? 551... Foreign Manufacturers and Importers Designation of An Agent for Service of Process § 551.49 May a foreign manufacturer replace its agent? (a) Yes, a foreign manufacturer may replace its agent in the same way...

  5. Single implant tooth replacement.

    PubMed

    Briley, T F

    1998-01-01

    It has been shown that direct bone anchorage of dental implants will provide long-term predictability for single tooth implants and multi-unit implants. The function of implant-supported restoration is now routinely achieved. The real challenge facing the restorative dentist and laboratory technician is to achieve optimal aesthetics. The learning objective of this article is to review the prosthodontic procedures essential to maximizing natural aesthetics in implant supported restorations. It will provide a review of master impression techniques, prepable titanium abutments and designing the cement on restoration. Particular emphasis is directed to the soft tissue model from which a series of sequenced techniques can be followed to achieve optimal aesthetics. Analysis of the implant alignment with regard to the neighboring teeth will result in having to make a choice of which prepable abutment will maximize the aesthetic result. The following case outlines how to replace a single missing tooth using an externally hexed implant system and a prefabricated titanium abutment on a 26-year-old male patient.

  6. Reuse, replace, recycle

    PubMed Central

    McMurray, Michael A.; Thorner, Jeremy W.

    2015-01-01

    Septins are guanine nucleotide-binding proteins that form hetero-oligomeric complexes, which assemble into filaments and higher-order structures at sites of cell division and morphogenesis in eukaryotes. Dynamic changes in the organization of septin-containing structures occur concomitantly with progression through the mitotic cell cycle and during cell differentiation. Septins also undergo stage-specific post-translational modifications, which have been implicated in regulating their dynamics, in some cases via purported effects on septin turnover. In our recent study, the fate of two of the five septins expressed in mitotic cells of budding yeast (Saccharomyces cerevisiae) was tracked using two complementary fluorescence-based methods for pulse-chase analysis. During mitotic growth, previously-made molecules of both septins (Cdc10 and Cdc12) persisted through multiple successive divisions and were incorporated equivalently with newly synthesized molecules into hetero-oligomers and higher-order structures. Similarly, in cells undergoing meiosis and the developmental program of sporulation, pre-existing copies of Cdc10 were incorporated into new structures. In marked contrast, Cdc12 was irreversibly excluded from septin complexes and replaced by another septin, Spr3. Here, we discuss the broader implications of these results and related findings with regard to how septin dynamics is coordinated with the mitotic cell cycle and in the yeast life cycle, and how these observations may relate to control of the dynamics of other complex multi-subunit assemblies. PMID:19164941

  7. Hormone replacement therapy.

    PubMed

    Scharbo-Dehaan, M

    1996-12-01

    More than 40 million women in the United States are now going through or are past menopause. Another 3.5 million or more will reach midlife in the next decade. As their life expectancy increases (mean life expectancy of women is now approximately 84 years), so does the need for therapeutic regimens related to reproductive function and aging in woman. Few medical treatments available to menopausal and postmenopausal women have as much potential benefit as well as possible health risks as hormone replacement therapy (HRT). Despite the increasing amount of scientific data available regarding the benefits of HRT, a degree of uncertainty still remains, both in the minds of some women, and with some health professionals, regarding the risks associated with long-term therapy. Even though the literature is voluminous, contradictory, and unclear, health providers must be able to keep abreast of current knowledge about the benefits, risks, and unknowns of these drugs. The purpose of this article is to provide a review and an update on the types of hormones available for HRT, their pharmacology and pharmacokinetics, and their risks, benefits, and contraindications. Newer products, specially compounded formulas, new regimens, and new modes of delivery that offer women alternatives and allow care to be individualized are described. In addition, some of the ongoing management dilemmas that practitioners face with the woman who chooses HRT are presented with practical solutions and suggestions.

  8. 2707SX FACP replacement

    SciTech Connect

    Ferry, M.F.

    1994-11-17

    This Acceptance Test Procedure (ATP) has been prepared to demonstrate that the Fire Protection system functions as required by project criteria. This ATP will test the Pyrotronic CP-400 fire alarm control panel (FACP), and interfaces with the radio fire alarm reporting box, alarm/supervisory initiating devices, and alarm indicating appliances. This document is to certify the installation of the fire alarm control panel and all attached devices to insure the Hanford Fire Dept. receives the proper signals. This particular fire alarm control panel services Bldg. 2707SX in the 200W Area of Hanford.

  9. A minority research and education information service: Design, develop, pilot test, and implement on-line access for historically black colleges and universities and government agencies. Annual status report, September 28, 1992--September 27, 1993

    SciTech Connect

    Rodman, J.A.

    1993-08-01

    The goal of the MOLIS project was to develop, design, and pilot test on-line access to current information on minority colleges and universities as well as federal minority opportunities. Federal Information Exchange, Inc. (FIE), a diversified information services company recognized by researchers and educators as a leader in the field of information delivery services, was awarded a 5 year small business research grant to develop and implement MOLIS. Since going on-line on April 29, 1991, MOLIS has provided current information on 138 Black and Hispanic colleges and universities -- including faculty and student profiles, financial data, research centers and equipment information, precollege and education programs, emerging capabilities, enrollment data, administrative personnel data, and current events -- as well as minority opportunities from participating federal agencies. Six federal agencies are currently participating in MOLIS, including: Agency for International Development; Department of Commerce; Department of Energy; Department of Housing and Urban Development; National Aeronautics and Space Administration; and National Science Foundation.

  10. The Learners' Satisfaction toward Online E-Learning Implemented in the College of Applied Studies and Community Service, King Saud University, Saudi Arabia: Can E-Learning Replace the Conventional System of Education?

    ERIC Educational Resources Information Center

    Al-Fahad, Fahad N.

    2010-01-01

    The growth of distance education course offerings is an indication of its importance to students. The purpose of this study is to investigate learners' satisfaction toward online e-learning implemented in the College of Applied Studies and Community Service, King Saud University, Riyadh, Saudi Arabia. In the meantime, also, this study was…

  11. Replacing mouse and trackball with tracked line of gaze

    NASA Astrophysics Data System (ADS)

    Schroeder, William E.

    1993-10-01

    Foster-Miller has recently demonstrated a prototype eye-slaved target acquisition interface for the AEGIS workstation system, the `Visual Trackball.' In proof-of-principle stage it functioned: hands-free, head free (no head tracker or `fiducial mark'), immediately at a high level without training, losing and recurring the eye (when the user looked away), with glasses (but not sharp division bifocals) and contacts, and, most importantly, twice as fast as a trackball in a controlled test (for novice and experienced users). Progress was made on two obstacles to a practical eye tracking computer interface: (1) moving a research technology out of the laboratory into the real world, and (2) using a sensor (the eye) as a communications channel. By taking subjects at random and asking them to perform a simulation of the AEGIS target acquisition task with no preparation and little training, much real-world experience was gained about glasses, eyelashes and eyelids, and people's ability to compensate for system and procedural deficiencies. Problem behaviors were identified for later work. The prototype had some `customizable' features. Three methods of feeding back calculated eye-gaze were tried. Smoothing of raw eye gaze data was also adjustable. Scope exists for improved function by fitting these factors to the user.

  12. Antenna Controller Replacement Software

    NASA Technical Reports Server (NTRS)

    Chao, Roger Y.; Morgan, Scott C.; Strain, Martha M.; Rockwell, Stephen T.; Shimizu, Kenneth J.; Tehrani, Barzia J.; Kwok, Jaclyn H.; Tuazon-Wong, Michelle; Valtier, Henry; Nalbandi, Reza; Wert, Michael; Leung, Patrick

    2010-01-01

    The Antenna Controller Replacement (ACR) software accurately points and monitors the Deep Space Network (DSN) 70-m and 34-m high-efficiency (HEF) ground-based antennas that are used to track primarily spacecraft and, periodically, celestial targets. To track a spacecraft, or other targets, the antenna must be accurately pointed at the spacecraft, which can be very far away with very weak signals. ACR s conical scanning capability collects the signal in a circular pattern around the target, calculates the location of the strongest signal, and adjusts the antenna pointing to point directly at the spacecraft. A real-time, closed-loop servo control algorithm performed every 0.02 second allows accurate positioning of the antenna in order to track these distant spacecraft. Additionally, this advanced servo control algorithm provides better antenna pointing performance in windy conditions. The ACR software provides high-level commands that provide a very easy user interface for the DSN operator. The operator only needs to enter two commands to start the antenna and subreflector, and Master Equatorial tracking. The most accurate antenna pointing is accomplished by aligning the antenna to the Master Equatorial, which because of its small size and sheltered location, has the most stable pointing. The antenna has hundreds of digital and analog monitor points. The ACR software provides compact displays to summarize the status of the antenna, subreflector, and the Master Equatorial. The ACR software has two major functions. First, it performs all of the steps required to accurately point the antenna (and subreflector and Master Equatorial) at the spacecraft (or celestial target). This involves controlling the antenna/ subreflector/Master-Equatorial hardware, initiating and monitoring the correct sequence of operations, calculating the position of the spacecraft relative to the antenna, executing the real-time servo control algorithm to maintain the correct position, and

  13. Using your shoulder after replacement surgery

    MedlinePlus

    Joint replacement surgery - using your shoulder; Shoulder replacement surgery - after ... You have had shoulder replacement surgery to replace the bones of your shoulder joint with artificial parts. The parts include a stem made of metal and a ...

  14. Educating My Replacement

    NASA Astrophysics Data System (ADS)

    Tarter, Jill

    , in partnership with the dedicated teachers out there, I think I can help promote the critical thinking skills and scientific literacy of the next generation of voters. Hopefully, I can also help train my replacement to be a better scientist, capable of seizing all the opportunities generated by advances in technology and our improved understanding of the universe to craft search strategies with greater probability of success than those I have initiated.

  15. [Ascending aorta replacement late after aortic valve replacement].

    PubMed

    Hayashi, Yasunari; Ito, Toshiaki; Maekawa, Atsuo; Sawaki, Sadanari; Fujii, Genyo; Hoshino, Satoshi; Tokoro, Masayoshi; Yanagisawa, Junji

    2013-07-01

    Replacement of the asceding aorta is indicated in patients undergoing aortic valve replacement( AVR), if the diameter of the ascending aorta is greater than 5.0 cm. If the diameter of the asceding aorta is from 4.0 to 5.0 cm, it was arguable whether replacement of the ascending aorta should be performed. Nine patients who underwent reoperative ascending aorta replacement after AVR were reviewed retrospectively. Reoperation on the asending aorta replacement was performed 11.8±7.2 years (range 1y5m~23y3m) after AVR. Mean patient age was 69.9±6.3 (range 60~81). In 2 cases, reoperations were performed early year after AVR. Although ascending aorta was dilated at the 1st operation, replacement wasn't performed for the age and minimally invasive cardiac surgery (MICS). In 3 cases, reoperations were performed more than 10 years later. On these cases, ascending aorta aneurysm and dissection occurred with no pain and were pointed out by computed tomography(CT) or ultrasonic cardiogram(UCG). We think that patients with dilatation of the ascending aorta should undergo AVR and aorta replacement at the 1st operation regardness of age. It is important that patients who underwent AVR should undergo a regular checkup on the ascending aorta.

  16. Replace with abstract title

    NASA Astrophysics Data System (ADS)

    Johnson, Tracey; Sato, Yu; Chiang, Shirley; Hochstrasser, Michael; Tobin, Jim; Giacomo, Jason; Shine, Jacob; Zhu, Xiangdong; Land, Donald; Arena, Dario; Morton, Simon; Waddill, George

    2002-03-01

    We are studying layer-by-layer synthesis of ultra-thin metal films by controlling at the monolayer level the composition and structure of these films, including the interfacial region. We have prepared Fe_xNi_1-x multilayers using simultaneous evaporation of pure Fe and Ni on Cu(111) in order to better understand the Giant Magnetoresistance (GMR) effect in FeNi/Cu systems that are relevant to magnetic disk drive heads. Using Undulator Beamline 7.0 and the Spin Spectroscopy Facility (7.0.1.2) at the ALS, we have measured X-ray Magnetic Linear Dichroism (XMLD) signals for twenty three different thin Fe-Ni alloys films on Cu(111) for different thicknesses and with Fe concentration ranging from 9% to 84%. X-ray Photoelectron Spectroscopy (XPS) with 1250 eV photon energy was utilized to determine both thickness and elemental composition. The Fe3p and Ni3p lines were measured for magnetization up and down, and the difference is the XMLD signal. Our XMLD spectra clearly indicate that samples of specific thicknesses and Fe concentrations are ferromagnetic. XMLD has previously been used to characterize Fe_xNi_1-x alloy fcc multilayers on Cu(100) .

  17. Fully functional bioengineered tooth replacement as an organ replacement therapy

    PubMed Central

    Ikeda, Etsuko; Morita, Ritsuko; Nakao, Kazuhisa; Ishida, Kentaro; Nakamura, Takashi; Takano-Yamamoto, Teruko; Ogawa, Miho; Mizuno, Mitsumasa; Kasugai, Shohei; Tsuji, Takashi

    2009-01-01

    Current approaches to the development of regenerative therapies have been influenced by our understanding of embryonic development, stem cell biology, and tissue engineering technology. The ultimate goal of regenerative therapy is to develop fully functioning bioengineered organs which work in cooperation with surrounding tissues to replace organs that were lost or damaged as a result of disease, injury, or aging. Here, we report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. We propose this technology as a model for future organ replacement therapies. The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues. This study represents a substantial advance and emphasizes the potential for bioengineered organ replacement in future regenerative therapies. PMID:19666587

  18. Fully functional bioengineered tooth replacement as an organ replacement therapy.

    PubMed

    Ikeda, Etsuko; Morita, Ritsuko; Nakao, Kazuhisa; Ishida, Kentaro; Nakamura, Takashi; Takano-Yamamoto, Teruko; Ogawa, Miho; Mizuno, Mitsumasa; Kasugai, Shohei; Tsuji, Takashi

    2009-08-11

    Current approaches to the development of regenerative therapies have been influenced by our understanding of embryonic development, stem cell biology, and tissue engineering technology. The ultimate goal of regenerative therapy is to develop fully functioning bioengineered organs which work in cooperation with surrounding tissues to replace organs that were lost or damaged as a result of disease, injury, or aging. Here, we report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. We propose this technology as a model for future organ replacement therapies. The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues. This study represents a substantial advance and emphasizes the potential for bioengineered organ replacement in future regenerative therapies.

  19. Double targeted gene replacement for creating null mutants.

    PubMed Central

    Cruz, A; Coburn, C M; Beverley, S M

    1991-01-01

    We have used double gene targeting to create homozygous gene replacements in the protozoan parasite Leishmania major, an asexual diploid. This method uses two independent selectable markers in successive rounds of gene targeting to replace both alleles of an endogenous gene. We developed an improved hygromycin B-resistance cassette encoding hygromycin phosphotransferase (HYG) for use as a selectable marker for Leishmania. HYG-containing vectors functioned equivalently to those containing the neomycin phosphotransferase (NEO) cassette previously used for extrachromosomal transformation or gene targeting. Drug resistances conferred by the NEO and HYG markers were independent, allowing simultaneous selection for both markers. A HYG targeting vector was utilized to replace the single dihydrofolate reductase-thymidylate synthase (DHFR-TS) gene remaining in a line heterozygous for a NEO replacement at the dhfr-ts locus (+/neo), with a targeting efficiency comparable to that seen with wild-type recipients. The resultant dhfr-ts- line (hyg/neo) was auxotrophic for thymidine. The double targeted replacement method will enable functional genetic testing in a variety of asexual diploids, including cultured mammalian cells and fungi such as Candida albicans. Additionally, it may be possible to use Leishmania bearing conditionally auxotrophic gene replacements as safe, improved live vaccines for leishmaniasis. Images PMID:1651496

  20. Double targeted gene replacement for creating null mutants.

    PubMed

    Cruz, A; Coburn, C M; Beverley, S M

    1991-08-15

    We have used double gene targeting to create homozygous gene replacements in the protozoan parasite Leishmania major, an asexual diploid. This method uses two independent selectable markers in successive rounds of gene targeting to replace both alleles of an endogenous gene. We developed an improved hygromycin B-resistance cassette encoding hygromycin phosphotransferase (HYG) for use as a selectable marker for Leishmania. HYG-containing vectors functioned equivalently to those containing the neomycin phosphotransferase (NEO) cassette previously used for extrachromosomal transformation or gene targeting. Drug resistances conferred by the NEO and HYG markers were independent, allowing simultaneous selection for both markers. A HYG targeting vector was utilized to replace the single dihydrofolate reductase-thymidylate synthase (DHFR-TS) gene remaining in a line heterozygous for a NEO replacement at the dhfr-ts locus (+/neo), with a targeting efficiency comparable to that seen with wild-type recipients. The resultant dhfr-ts- line (hyg/neo) was auxotrophic for thymidine. The double targeted replacement method will enable functional genetic testing in a variety of asexual diploids, including cultured mammalian cells and fungi such as Candida albicans. Additionally, it may be possible to use Leishmania bearing conditionally auxotrophic gene replacements as safe, improved live vaccines for leishmaniasis.

  1. INNOPLANT Total Hip Replacement System.

    PubMed

    Harper, Tisha A M

    2017-07-01

    Total hip replacement is a salvage procedure that is done to alleviate discomfort secondary to osteoarthritis in the hip, which is most often a result of hip dysplasia. Commercially available total hip replacement implants for small animal patients are classified as cemented or cementless. The INNOPLANT Total Hip Replacement system includes modular, screw-in cementless components that were developed to improve implant stability by maintaining as much normal anatomic structure, and by extension biomechanics of the coxofemoral joint, as possible. As a newer system, there are few data and no long-term studies available in the veterinary literature. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Selecting the column configuration with lowest media replacement cost for small adsorption systems.

    PubMed

    Bausk, Artem S; Dvorak, Bruce I

    2016-04-15

    A framework was developed for preliminary evaluation of the relative media replacement costs of three alternative column configurations used for adsorption systems with two vessels, such as those serving small systems. The media replacement cost is the cost of fresh media and the replacement service cost (including transportation, labor, and other non-material costs). Cost normalization methods were developed in part based on the data from US EPA Arsenic Treatment Technology Demonstration Program. Adsorption equilibrium and kinetics were modeled using the PSDM model and breakthrough curves were normalized using the target effluent to influent concentration ratio (C/Co) and the mass transfer zone fraction (%MTZBT). Two factors were found to be important for the relative replacement cost of each configuration - the frequency which at least one column needed replacement of media, and the cycle replacement cost (CRCost) which is a combination of the fresh media cost and the replacement service cost. The lead-lag configuration has the lowest annual replacement cost at low target C/Co, high %MTZBT, and high CRCost ratios. The parallel configuration performs better at high target C/Co, high %MTZBT, and high CRCost ratios. Although the single configuration (two columns operated in tandem and replaced simultaneously) has higher media consumption compared to lead-lag and parallel, it can result in the lowest replacement cost at short %MTZBT and very low CRCost ratios due to savings in the replacement service cost.

  3. Fracture After Total Hip Replacement

    MedlinePlus

    ... er Total Hip Replacement cont. • Dislocation • Limb length inequality • Poor fracture healing • Repeat fracture • Lack of in- ... Surgeons (AAOS). To learn more about your orthopaedic health, please visit orthoinfo.org. Page ( 5 ) AAOS does ...

  4. An encephalocele replacing nose completely.

    PubMed

    Dasgupta, G

    1999-01-01

    Congenital encephalocele presenting in the nasal region is extremely rare. We present here a case ot tncephaloce lecompletely replacing the nose of a five year old boy and duscuss about similar swellings in this region.

  5. What Is a Hip Replacement?

    MedlinePlus

    ... reduce joint pain and stiffness. It can increase muscle strength and joint range of motion (how much you ... goals after hip replacement surgery are to: Increase muscle strength Increase your blood circulation and overall fitness Avoid ...

  6. Single Project Replaces District's Windows.

    ERIC Educational Resources Information Center

    American School and University, 1981

    1981-01-01

    The towns of Maplewood and South Orange (New Jersey) earmarked over $1 million, raised from a bond issue, to replace with thermal aluminum-framed units the 2400 worn out windows in eight 50-year-old schools. (Author)

  7. The development and testing of new nicotine replacement treatments: from 'nicotine replacement' to 'smoking replacement'.

    PubMed

    Hajek, Peter

    2015-07-01

    Griffith Edwards, unusually in the 1970s, saw tobacco use as falling within the remit of addiction research, and brought Michael Russell to the Addiction Research Unit [ARU] to initiate research into smoking. The work of the tobacco section of ARU paved the way to a better understanding of tobacco dependence and to developing nicotine replacement treatments. Michael Russell pioneered the idea of attractive nicotine replacement products with an acceptable safety profile replacing cigarettes on the open market and ending the tobacco epidemic, envisaging a transition from medicinal and temporary 'nicotine replacement' to recreational and potentially permanent 'smoking replacement'. Mike's prediction that the pharmaceutical industry would develop such devices did not materialize. Instead, two such products were generated by the tobacco industry (snus) and independent developers (electronic cigarettes). Another of Mike's hopes was that regulators would adopt rational policies, and that tobacco control activists would become supportive of smoking replacement once they thought through the implications. Until now, the 'smoking replacement' idea has been met with vigorous opposition from some tobacco control activists. The voices of researchers with historical links to ARU are prominent in arguing in favour of harm reduction and e-cigarettes. The most important debate ever to occur in tobacco control is under way and it carries the signature of Griffith Edwards' ARU. © 2015 Society for the Study of Addiction.

  8. Replacement of fluid-filter elements without interruption of flow

    NASA Technical Reports Server (NTRS)

    Kotler, R. A.; Ward, J. B.

    1969-01-01

    Gatling-type filter assembly, preloaded with several filter elements enables filter replacement without breaking into the operative fluid system. When the filter element becomes contaminated, a unit inner subassembly is rotated 60 degrees to position a clean filter in the line.

  9. Prioritization Methodology for Chemical Replacement

    NASA Technical Reports Server (NTRS)

    Cruit, W.; Schutzenhofer, S.; Goldberg, B.; Everhart, K.

    1993-01-01

    This project serves to define an appropriate methodology for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semiquantitative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weigh the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results are being implemented as a guideline for consideration for current NASA propulsion systems.

  10. The UKCIS Advisory Service.

    ERIC Educational Resources Information Center

    Bingham, Archie

    1979-01-01

    Describes the free advisory service available to both users and potential users of chemical and biological databases in the United Kingdom and Ireland. Three specific areas are discussed in which queries about Chemical Abstracts Service (CAS) Registry Numbers have been received: isomers, replacing registry numbers, and mixed compounds. (JD)

  11. The UKCIS Advisory Service.

    ERIC Educational Resources Information Center

    Bingham, Archie

    1979-01-01

    Describes the free advisory service available to both users and potential users of chemical and biological databases in the United Kingdom and Ireland. Three specific areas are discussed in which queries about Chemical Abstracts Service (CAS) Registry Numbers have been received: isomers, replacing registry numbers, and mixed compounds. (JD)

  12. On-Line Support and Portfolio Assessment for NETS-T Standards In Pre-Service Programs at a Large Southeastern University.

    ERIC Educational Resources Information Center

    Shoffner, Mary B.; Dias, Laurie B.

    This paper details the theoretical underpinnings of one university's approach to technology integration in its pre-service teacher preparation programs, and the results of a continuous, feedback-driven project to evaluate for technology integration through a student portfolio development process. Portfolios are assessed for multiple education and…

  13. 21 CFR 870.3710 - Pacemaker repair or replacement material.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Pacemaker repair or replacement material. 870.3710 Section 870.3710 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Prosthetic Devices § 870.3710 Pacemaker...

  14. 21 CFR 870.3925 - Replacement heart valve.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Replacement heart valve. 870.3925 Section 870.3925 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... completion of a PDP is required to be filed with the Food and Drug Administration on or before December...

  15. Measure Guideline. Wood Window Repair, Rehabilitation, and Replacement

    SciTech Connect

    Baker, P.; Eng, P.

    2012-12-01

    This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

  16. 7 CFR 550.39 - Equipment replacement insurance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Equipment replacement insurance. 550.39 Section 550.39 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT... of equipment acquired with Federal funds in the event of loss or damage to such equipment. ...

  17. CH-53K Heavy Lift Replacement Helicopter (CH-53K)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-390 CH-53K Heavy Lift Replacement Helicopter (CH-53K) As of FY 2017 President’s Budget...Estimate RDT&E - Research, Development, Test, and Evaluation SAR - Selected Acquisition Report SCP - Service Cost Position TBD - To Be Determined TY

  18. Prioritization methodology for chemical replacement

    NASA Technical Reports Server (NTRS)

    Cruit, Wendy; Goldberg, Ben; Schutzenhofer, Scott

    1995-01-01

    Since United States of America federal legislation has required ozone depleting chemicals (class 1 & 2) to be banned from production, The National Aeronautics and Space Administration (NASA) and industry have been required to find other chemicals and methods to replace these target chemicals. This project was initiated as a development of a prioritization methodology suitable for assessing and ranking existing processes for replacement 'urgency.' The methodology was produced in the form of a workbook (NASA Technical Paper 3421). The final workbook contains two tools, one for evaluation and one for prioritization. The two tools are interconnected in that they were developed from one central theme - chemical replacement due to imposed laws and regulations. This workbook provides matrices, detailed explanations of how to use them, and a detailed methodology for prioritization of replacement technology. The main objective is to provide a GUIDELINE to help direct the research for replacement technology. The approach for prioritization called for a system which would result in a numerical rating for the chemicals and processes being assessed. A Quality Function Deployment (QFD) technique was used in order to determine numerical values which would correspond to the concerns raised and their respective importance to the process. This workbook defines the approach and the application of the QFD matrix. This technique: (1) provides a standard database for technology that can be easily reviewed, and (2) provides a standard format for information when requesting resources for further research for chemical replacement technology. Originally, this workbook was to be used for Class 1 and Class 2 chemicals, but it was specifically designed to be flexible enough to be used for any chemical used in a process (if the chemical and/or process needs to be replaced). The methodology consists of comparison matrices (and the smaller comparison components) which allow replacement technology

  19. Caterpillar Chrome Plate Replacement Technology

    DTIC Science & Technology

    2010-06-16

    Supplier Contract Reman New / Reman Order Processing Procurement Supplier Development Kitting Core Processing Core Purchase Transportation Packaging ... Design Customs Core Criteria New Product Intro. Reman Strategy Customer Service Obsolescence Mgmt Production Transition Dealer Channel Services Used Parts

  20. Sexual Assault and Sexual Harassment in the U.S. Military: Top-Line Estimates for Active-Duty Service Members from the 2014 RAND Military Workplace Study

    DTIC Science & Technology

    2014-01-01

    62 percent who filed such a report indicated that they experienced professional retali- ation, social retaliation, adverse administrative actions, or...encouraged the RAND research team to rede - sign the approach used previously in the WGRA surveys if changes would improve the accuracy and validity of the...communications plan that promoted the survey through many channels, including social media, public service announcements, and print news stories. A total of

  1. [Hip replacement in military personnel].

    PubMed

    Maksimov, I B; Paniushin, K A; Brizhan', L K; Buriachenko, B P; Varfolomeev, D I; Mimanchev, O V

    2014-01-01

    Hip joint diseases and injuries are common for orthopedic pathology among military personnel. Hip replacement is one of the most frequent operations. Authors evaluated hip replacement in 136 servicemen treated at the center of traumatology and orthopedics of Burdenko General Military Clinical Hospital of the Ministry of Defense of Russia in 2010-2013. On the basis of the conducted analysis the main disease groups were revealed, peculiarities of pathology among this category of patients. Authors proposed surgical doctrine for the treatment of this contingent. Effective surgical treatment, in particular, hip replacement surgery, conducted with the use of the proposed principles, as a rule, fully functionally cured patients and contributes to return them in the system that contributes to the strengthening of defensibility of the country.

  2. Prioritization methodology for chemical replacement

    NASA Technical Reports Server (NTRS)

    Goldberg, Ben; Cruit, Wendy; Schutzenhofer, Scott

    1995-01-01

    This methodology serves to define a system for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi quantitative approach derived from quality function deployment techniques (QFD Matrix). QFD is a conceptual map that provides a method of transforming customer wants and needs into quantitative engineering terms. This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives.

  3. [Nicotine replacement therapy during pregnancy].

    PubMed

    Jiménez Ruiz, Carlos A

    2006-08-01

    In spite of the fact that smoking is the main cause of obstetric morbidity and mortality, 20% of North American women smoke during pregnancy. In Spain, this figure is as high as 30% to 35%. Treating smoking addiction in these patients should be the first and most important therapeutic measure undertaken by health professionals responsible for the care of pregnant women. All experts recommend the use of nicotine replacement therapy when more conservative treatments have failed. This article reviews the indications and contraindications for nicotine replacement therapy during pregnancy as well as other issues relating to the safety of this type of treatment.

  4. Prioritization methodology for chemical replacement

    NASA Technical Reports Server (NTRS)

    Goldberg, Ben; Cruit, Wendy; Schutzenhofer, Scott

    1995-01-01

    This methodology serves to define a system for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi quantitative approach derived from quality function deployment techniques (QFD Matrix). QFD is a conceptual map that provides a method of transforming customer wants and needs into quantitative engineering terms. This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives.

  5. Preliminary study of possible ORELA replacement options

    SciTech Connect

    Olsen, D.K.; Martin, J.A.; Horen, D.J.

    1984-06-01

    Based on two conceptual design studies performed by the LANL Accelerator Technology Division, the possibilities in terms of accelerator systems for replacing ORELA with a more intense Maxwellian-type continuous-energy neutron source are summarized and discussed. The neutron intensities from ORELA are compared with those from existing or potential accelerator systems used for cross-section and condensed-matter studies. The best replacement options seem to involve a spallation source from 200- to 400-MeV protons on an ORELA-like target. Pulsing and intensity desiderata with such a source are discussed which correspond to a spectrum-averaged 100-fold improved figure of merit over ORELA for TOF measurements with only a tenfold increased source strength. Existing accelerator designs seem to be inadequate for such a source. Consequently, two conceptual designs were developed for this study by the LANL Accelerator Technology Division. The first conceptual design is for a 200-MeV large linac capable of accelerating 1.3 A during a macropulse; this linac standing alone could serve as an ORELA replacement source. The second conceptual design is for a much smaller 250-MeV PIGMI linac with a 28-mA macropulse current which feeds a proton accumulator ring and bunch-compressor transport line. This linac-ring-compressor (LIRIC) option would give a more cost-effective neutron source for cross-section measurements, whereas the large linac, or a modified version of it, would give a much simpler system more suitable for expansion. In particular, both conceptual designs would incorporate the present ORELA building and would provide approximately 100-fold improved neutron sources over ORELA for cross-section measurements. The total estimated cost of the LIRIC system would be $43M (1984), whereas the cost of the large linac would be about a factor of two more. 55 references, 11 figures, 19 tables.

  6. The present development of time service in Brazil, with the application of the TV line-10 method for coordination and synchronization of atomic clocks

    NASA Technical Reports Server (NTRS)

    Silva, P. M.; Silva, I. M.

    1974-01-01

    Various methods presently used for the dissemination of time at several levels of precision are described along with future projects in the field. Different aspects of time coordination are reviewed and a list of future laboratories participating in a National Time Scale will be presented. A Brazilian Atomic Time Scale will be obtained from as many of these laboratories as possible. The problem of intercomparison between the Brazilian National Time Scale and the International one will be presented and probable solutions will be discussed. Needs related to the TV Line-10 method will be explained and comments will be made on the legal aspects of time dissemination throughout the country.

  7. Metabolite identification of halon replacement compounds

    NASA Astrophysics Data System (ADS)

    Brashear, W. T.; Ketcha, M. M.; Pollard, D. L.; Godin, C. S.; Leahy, H. F.

    1992-06-01

    Halon 1211 is currently being used by the U.S. Air Force as a flight line fire extinguishant. Because of health and environmental concerns over ozone depletion, Halon 1211 must be phased out by the year 2000. Before an interim replacement can be chosen, the toxicity of prospective candidates needs to be evaluated. The metabolism was studied of the Halon replacement candidates perfluorohexane (PFH) and the hydrochlorofluorocarbons (HCFCs): HCFC-123, HCFC-124, and HCFC-142b. Fischer 344 and Sprague-Dawley rats were exposed via inhalation to a 1 pct. atmosphere for 2 h. Tissues were analyzed for volatile metabolites, and urine was analyzed for fluoride and carboxylic acid metabolites. Animals exposed to HCFC-123 or IICFC-124 excreted trifluoroacetic acid in their urine. The presence of trifluoroacetic acid indicates oxidative metabolism of HCFC-123 and IICFC-124. Increased fluoride was found in the urine of rats exposed to HCFC-124. HCFC-142b was metabolized to chlorodifluoroacetic acid, which was found in the urine of exposed rats. Fischer 344 and Sprague-Dawley rats exposed to HCFC-123 had small amounts of HCFC-133a and 2-chloro-1,1-difluoroethylene in liver tissue. The identification of HCFC-133a and 2-chloro-1,1-difluoroethylene following exposure indicates reductive metabolism of HCFC-123. No metabolites of PFH or Halon 1211 were identified in these investigations. Rats exposed to Halon 1211 had slightly elevated bromide levels in their urine compared to control values.

  8. TOWER 1 IN CENTER,REPLACEMENT MODEL SINGLE CHAIR IN FOREGROUND, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOWER 1 IN CENTER,REPLACEMENT MODEL SINGLE CHAIR IN FOREGROUND, LOOKING SOUTHWEST UP THE LIFT LINE. - Mad River Glen, Single Chair Ski Lift, 62 Mad River Glen Resort Road, Fayston, Washington County, VT

  9. Zone lines

    Treesearch

    Kevin T. Smith

    2001-01-01

    Zone lines are narrow, usually dark markings formed in decaying wood. Zone lines are found most frequently in advanced white rot of hardwoods, although they occasionally are associated both with brown rot and with softwoods.

  10. Replaceable Sleeve Protects Welder Coil

    NASA Technical Reports Server (NTRS)

    Baker, W. L.; Simpson, C., E.

    1983-01-01

    New replaceable carbon insert for deflection coil in electron-beam welder promises to decrease maintenance costs. Inserts made from materials other than carbon (not yet tried) are less expensive, thus reducing costs even further. With carbon insert, deflection coils last longer and are easier to maintain.

  11. Will peanut hulls replace oil

    SciTech Connect

    Not Available

    1980-12-01

    A low-cost, fast-curing wood adhesive has been recently developed by the University of Georgia, in which up to 80% of the petroleum ingredients can be replaced with a substance extracted from peanut hulls. An outline of the process is given.

  12. Replaceable Sleeve Protects Welder Coil

    NASA Technical Reports Server (NTRS)

    Baker, W. L.; Simpson, C., E.

    1983-01-01

    New replaceable carbon insert for deflection coil in electron-beam welder promises to decrease maintenance costs. Inserts made from materials other than carbon (not yet tried) are less expensive, thus reducing costs even further. With carbon insert, deflection coils last longer and are easier to maintain.

  13. MELFI-3 Electronic Unit Replacement

    NASA Image and Video Library

    2011-07-01

    ISS028-E-013797 (1 July 2011) --- NASA astronaut Mike Fossum, Expedition 28 flight engineer, replaces a failed electronic unit for the Minus Eighty Laboratory Freezer for ISS 3 (MELFI-3) with a spare unit in the Kibo laboratory of the International Space Station.

  14. MELFI-3 Electronic Unit Replacement

    NASA Image and Video Library

    2011-07-01

    ISS028-E-013799 (1 July 2011) --- NASA astronaut Mike Fossum, Expedition 28 flight engineer, replaces a failed electronic unit for the Minus Eighty Laboratory Freezer for ISS 3 (MELFI-3) with a spare unit in the Kibo laboratory of the International Space Station.

  15. Toward replacement fertility in Egypt and Tunisia.

    PubMed

    Eltigani, Eltigani E

    2009-09-01

    Egypt and Tunisia began their fertility transition at almost identical fertility levels and at roughly the same time period, yet the difference in the pace of decline has been such that the total fertility rate (TFR) in Tunisia reached replacement level by the year 2001, whereas the TFR in Egypt remains above three live births per woman. This article draws on the secondary literature and on several nationally representative surveys from the two countries between 1978 and 2005 to provide empirical evidence of the difference in the pace of fertility decline and to analyze the determinants of the differential. Findings include (a) variation across the two countries in the consistency of fertility decline among the segments of the population leading the transition; (b) that the success of each country's family planning program was influenced by the role of political leaders and the extent of the program's integration within socioeconomic development objectives; (c) that the impact of contraception on TFR decline became an important factor in the mid-1980s; and (d) that the greatest determinant of the discrepancy in the pace of fertility decline is the disparity in age at marriage, which rose more significantly in Tunisia than in Egypt. The latter finding indicates that reaching replacement fertility in Egypt hinges primarily on further declines in marital fertility, resulting from reduction of wanted fertility and from an expansion of family planning program coverage and improved efficiency of service delivery and use.

  16. Botas line repaired ahead of schedule

    SciTech Connect

    Not Available

    1991-11-01

    This paper reports on damaged sections of Botas' dual 30-in. gas line carrying USSR gas across the Marmara Sea to Turkey that were replaced 30 days ahead of contract schedule. Tefken Construction and Installation Co., Inc., Istanbul, working under a $4-million contract, replaced two sections on one of the dual lines near Ambarli, Turkey, within a two-month period. The offshore system stretches 33-mi under the Marmara Sea with some pipe laid at 262-ft maximum water depths. The scope of the project was to replace a 426-ft offshore approach to the northern shoreline and a 984-ft onshore section, which were damaged by a submarine landslide.

  17. Measure Lines

    ERIC Educational Resources Information Center

    Crissman, Sally

    2011-01-01

    One tool for enhancing students' work with data in the science classroom is the measure line. As a coteacher and curriculum developer for The Inquiry Project, the author has seen how measure lines--a number line in which the numbers refer to units of measure--help students not only represent data but also analyze it in ways that generate…

  18. Bonding over Dentin Replacement Materials.

    PubMed

    Meraji, Naghmeh; Camilleri, Josette

    2017-08-01

    Dentin replacement materials are necessary in large cavities to protect the pulp and reduce the bulk of filling material. These materials are layered with a composite resin restorative material. Microleakage caused by poor bonding of composite resin to underlying dentin replacement material will result in pulp damage. The aim of this study was to characterize the interface between dentin replacement materials and composite resin and to measure the shear bond strength after dynamic aging. Biodentine (Septodont, Saint Maur-des-Fosses, France), Theracal LC (Bisco, Schaumburg, IL), and Fuji IX (GC, Tokyo, Japan) were used as dentin replacement materials. They were then overlaid with a total-etch and bonding agent or a self-etch primer and composite resin or a glass ionomer cement. All combinations were thermocycled for 3000 cycles. The interface was characterized using scanning electron microscopy and elemental mapping. Furthermore, the shear bond strength was assessed. The Biodentine surface was modified by etching. The Theracal LC and Fuji IX microstructure was unchanged upon the application of acid etch. The Biodentine and glass ionomer interface showed an evident wide open space, and glass particles from the glass ionomer adhered to the Biodentine surface. Elemental migration was shown with aluminum, barium, fluorine, and ytterbium present in Biodentine from the overlying composite resin. Calcium was more stable. The bond strength between Theracal LC and composite using a total-etch technique followed by self-etch primer achieved the best bond strength values. Biodentine exhibited the weakest bond with complete failure of bonding shown after demolding and thermocycling. Dynamic aging is necessary to have clinically valid data. Bonding composite resin to water-based dentin replacement materials is still challenging, and further alternatives for restoration of teeth using such materials need to be developed. Copyright © 2017 American Association of Endodontists

  19. 7 CFR 301.75-17 - Funds for the replacement of certified citrus nursery stock.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Funds for the replacement of certified citrus nursery...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Canker Notice of Quarantine and Regulations § 301.75-17 Funds for the replacement of certified...

  20. 7 CFR 301.75-17 - Funds for the replacement of certified citrus nursery stock.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 5 2013-01-01 2013-01-01 false Funds for the replacement of certified citrus nursery...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Canker Notice of Quarantine and Regulations § 301.75-17 Funds for the replacement of certified...

  1. 7 CFR 301.75-17 - Funds for the replacement of certified citrus nursery stock.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 5 2011-01-01 2011-01-01 false Funds for the replacement of certified citrus nursery...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Canker Notice of Quarantine and Regulations § 301.75-17 Funds for the replacement of certified...

  2. 7 CFR 301.75-17 - Funds for the replacement of certified citrus nursery stock.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 5 2012-01-01 2012-01-01 false Funds for the replacement of certified citrus nursery...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Canker Notice of Quarantine and Regulations § 301.75-17 Funds for the replacement of certified...

  3. 7 CFR 301.75-17 - Funds for the replacement of certified citrus nursery stock.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Funds for the replacement of certified citrus nursery...) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE DOMESTIC QUARANTINE NOTICES Citrus Canker Notice of Quarantine and Regulations § 301.75-17 Funds for the replacement of certified...

  4. 24 CFR 960.609 - Prohibition against replacement of PHA employees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PHA employees. 960.609 Section 960.609 Housing and Urban Development REGULATIONS RELATING TO HOUSING... replacement of PHA employees. In implementing the service requirement under this subpart, the PHA may not... performed by PHA employees, or replace a job at any location where residents perform activities to satisfy...

  5. 24 CFR 960.609 - Prohibition against replacement of PHA employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PHA employees. 960.609 Section 960.609 Housing and Urban Development Regulations Relating to Housing... replacement of PHA employees. In implementing the service requirement under this subpart, the PHA may not... performed by PHA employees, or replace a job at any location where residents perform activities to satisfy...

  6. 24 CFR 960.609 - Prohibition against replacement of PHA employees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PHA employees. 960.609 Section 960.609 Housing and Urban Development REGULATIONS RELATING TO HOUSING... replacement of PHA employees. In implementing the service requirement under this subpart, the PHA may not... performed by PHA employees, or replace a job at any location where residents perform activities to satisfy...

  7. 24 CFR 960.609 - Prohibition against replacement of PHA employees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PHA employees. 960.609 Section 960.609 Housing and Urban Development REGULATIONS RELATING TO HOUSING... replacement of PHA employees. In implementing the service requirement under this subpart, the PHA may not... performed by PHA employees, or replace a job at any location where residents perform activities to satisfy...

  8. 24 CFR 960.609 - Prohibition against replacement of PHA employees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... PHA employees. 960.609 Section 960.609 Housing and Urban Development REGULATIONS RELATING TO HOUSING... replacement of PHA employees. In implementing the service requirement under this subpart, the PHA may not... performed by PHA employees, or replace a job at any location where residents perform activities to satisfy...

  9. 21 CFR 874.3540 - Prosthesis modification instrument for ossicular replacement surgery.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Prosthetic Devices... prosthesis modification instrument for ossicular replacement surgery is a device intended for use by a surgeon to construct ossicular replacements. This generic type of device includes the ear, nose,...

  10. 21 CFR 874.3540 - Prosthesis modification instrument for ossicular replacement surgery.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES EAR, NOSE, AND THROAT DEVICES Prosthetic Devices... prosthesis modification instrument for ossicular replacement surgery is a device intended for use by a surgeon to construct ossicular replacements. This generic type of device includes the ear, nose,...

  11. Replacing E-K pre-treat container and hose in АСУ system

    NASA Image and Video Library

    2006-11-29

    ISS014-E-08798 (29 Nov. 2006) --- Cosmonaut Mikhail Tyurin, Expedition 14 flight engineer, replaces the E-K pre-treat container and hose in the waste management system in the Zvezda Service Module of the International Space Station.

  12. 77 FR 31326 - Notice of Availability of a Final Supplemental Environmental Impact Statement for Replacement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... Supplemental Environmental Impact Statement for Replacement of NOAA National Marine Fisheries Service Southwest... and Atmospheric Administration (NOAA), Commerce. ACTION: Notice of availability of the Final Supplemental Environmental Impact Statement (SEIS); Opportunity for comments. SUMMARY: NOAA announces...

  13. VH Replacement Footprint Analyzer-I, a Java-Based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential VH Replacement Products in Human and Mouse.

    PubMed

    Huang, Lin; Lange, Miles D; Zhang, Zhixin

    2014-01-01

    VH replacement occurs through RAG-mediated secondary recombination between a rearranged VH gene and an upstream unrearranged VH gene. Due to the location of the cryptic recombination signal sequence (cRSS, TACTGTG) at the 3' end of VH gene coding region, a short stretch of nucleotides from the previous rearranged VH gene can be retained in the newly formed VH-DH junction as a "footprint" of VH replacement. Such footprints can be used as markers to identify Ig heavy chain (IgH) genes potentially generated through VH replacement. To explore the contribution of VH replacement products to the antibody repertoire, we developed a Java-based computer program, VH replacement footprint analyzer-I (VHRFA-I), to analyze published or newly obtained IgH genes from human or mouse. The VHRFA-1 program has multiple functional modules: it first uses service provided by the IMGT/V-QUEST program to assign potential VH, DH, and JH germline genes; then, it searches for VH replacement footprint motifs within the VH-DH junction (N1) regions of IgH gene sequences to identify potential VH replacement products; it can also analyze the frequencies of VH replacement products in correlation with publications, keywords, or VH, DH, and JH gene usages, and mutation status; it can further analyze the amino acid usages encoded by the identified VH replacement footprints. In summary, this program provides a useful computation tool for exploring the biological significance of VH replacement products in human and mouse.

  14. Line Creek improves efficiency

    SciTech Connect

    Harder, P.

    1988-04-01

    Boosting coal recovery rate by 8% and reducing fuel expense $18,000 annually by replacing two tractors, are two tangible benefits that Crows Nest Resources of British Columbia has achieved since overseas coal markets weakened in 1985. Though coal production at the 4-million tpy Line Creek open pit mine has been cut 25% from its 1984 level, morale among the pit crew remains high. More efficient pit equipment, innovative use of existing equipment, and encouragement of multiple skill development among workers - so people can be assigned to different jobs in the operation as situations demand - contribute to a successful operation.

  15. The replacement of serum by hormones in cell culture media.

    PubMed

    Sato, G; Hayashi, I

    1976-12-01

    The replacement of serum by hormones in cell culture media. (Reemplazo del suero por hormonas en el medio de cultivo de células). Arch. Biol. Med. Exper. 10: 120-121, 1976. The serum used in cell culture media can be replaced by a mixture of hormones and some accesory blood factors. The pituitary cell line GH3 can be grown in a medium in which serum is replaced by triiodothyronine, transferrin, parathormone, tyrotrophin releasing hormone and somatomedins. Hela and BHK cell strains can also be grown in serum free medium supplemented with hormones. Each cell type appears to have different hormonal requirements yet it may found that some hormones are required for most cell types.

  16. Pseudoaneurysm after ICD battery replacement.

    PubMed

    Schulz, S L; Lehmkuhl, H; Zipfel, K B; Hetzer, R

    2007-02-01

    False aneurysms of the extracranial carotid arteries are rare and mainly of traumatic origin. We report on a patient who presented with a sudden onset mass in his right neck 2 weeks after routine replacement of his ICD battery. He had received systemic anticoagulation since an aortic valve replacement 5 years before. By color Doppler sonography the mass was identified as a partly thrombosed false aneurysm originating from the common carotid artery. As no spontaneous resolution occurred during the following days the aneurysm was removed surgically 5 days later without further complications. However no connection to the common carotid artery was found at surgery. Yet in the histopathological examination the specimen showed the morphological characteristics of a pseudoaneurysm. There was no history of neck-trauma and no attempted vascular access during the recent operation.

  17. [MINIMALLY INVASIVE AORTIC VALVE REPLACEMENT].

    PubMed

    Tabata, Minoru

    2016-03-01

    Minimally invasive aortic valve replacement (MIAVR) is defined as aortic valve replacement avoiding full sternotomy. Common approaches include a partial sternotomy right thoracotomy, and a parasternal approach. MIAVR has been shown to have advantages over conventional AVR such as shorter length of stay and smaller amount of blood transfusion and better cosmesis. However, it is also known to have disadvantages such as longer cardiopulmonary bypass and aortic cross-clamp times and potential complications related to peripheral cannulation. Appropriate patient selection is very important. Since the procedure is more complex than conventional AVR, more intensive teamwork in the operating room is essential. Additionally, a team approach during postoperative management is critical to maximize the benefits of MIAVR.

  18. Hurricane intensity and eyewall replacement.

    PubMed

    Houze, Robert A; Chen, Shuyi S; Smull, Bradley F; Lee, Wen-Chau; Bell, Michael M

    2007-03-02

    Observations made during the historic 2005 hurricane season document a case of "eyewall replacement." Clouds outside the hurricane eyewall coalesce to form a new eyewall at a greater radius from the storm center, and the old eyewall dies. The winds in the new eyewall are initially weaker than those in the original eyewall, but as the new eyewall contracts, the storm reintensifies. Understanding this replacement mechanism is vital to forecasting variations in hurricane intensity. Processes in the "moat" region between the new and old eyewall have been particularly unclear. Aircraft data now show that the moat becomes dynamically similar to the eye and thus is converted into a region inimical to survival of the inner eyewall. We suggest that targeting aircraft to key parts of the storm to gain crucial input to high-resolution numerical models can lead to improvements in forecasting hurricane intensity.

  19. Gene replacement in Lactobacillus helveticus.

    PubMed Central

    Bhowmik, T; Fernández, L; Steele, J L

    1993-01-01

    An efficient method for gene replacement in Lactobacillus helveticus CNRZ32 was developed by utilizing pSA3 as an integration vector. This plasmid is stably maintained in CNRZ32 at 37 degrees C but is unstable at 45 degrees C. This method consisted of a two-step gene-targeting technique: (i) chromosomal integration of a plasmid carrying an internal deletion in the gene of interest via homologous recombination and (ii) excision of the vector and the wild-type gene via homologous recombination, resulting in gene replacement. By using this procedure, the chromosomal X-prolyl dipeptidyl aminopeptidase gene (pepXP) of CNRZ32 was successfully inactivated. Images PMID:8104928

  20. The NSINIC on-line system

    NASA Technical Reports Server (NTRS)

    Lev, Brian

    1991-01-01

    The NSI NIC on-line system is described in the form of view graphs. The following subject areas are covered: NSI history; the ADFTO's other on-line services; the current system; and the next generation of NSI NIC.

  1. Replacing the Message Service Component In an Integration Framework.

    DTIC Science & Technology

    1994-10-01

    routine: add- eventO if (event->type == Message && event->tt~pattern 1= NULL) tt-pattern-register(event->tt~pattern); A..4 ToolTalk Message Pattern...Message Pattern Destruction A.5.1 routine: free- eventO if (event->type == Message && event->tt~pattern 1= NULL) tt-free (event->tt~pattern); A.6

  2. Marketing for Online Bibliographic Services.

    ERIC Educational Resources Information Center

    Elias, Art

    1979-01-01

    With reference to the "BIOSIS Previews" magnetic tape service of BioSciences Information Service (BIOSIS), marketing patterns of on-line bibliographic products are examined and future possibilities are discussed, with emphasis on geographic distribution of usage, organizations and institutions employing on-line service, and their…

  3. Marketing for Online Bibliographic Services.

    ERIC Educational Resources Information Center

    Elias, Art

    1979-01-01

    With reference to the "BIOSIS Previews" magnetic tape service of BioSciences Information Service (BIOSIS), marketing patterns of on-line bibliographic products are examined and future possibilities are discussed, with emphasis on geographic distribution of usage, organizations and institutions employing on-line service, and their…

  4. Hinge total knee replacement revisited

    PubMed Central

    Cameron, Hugh U.; Hu, Cungen; Vyamont, Didier

    1997-01-01

    Objective To determine if aseptic loosening is a major problem in hinge total knee replacement. Design A cohort study. Setting A university-affiliated institute, specializing in elective orthopedic surgery. Patients Fifty-eight patients, mainly those requiring revision, in whom the conditions were such that it was felt only a totally constrained implant was appropriate. In 7 patients the implant was press-fitted; in the remainder it was cemented. Five patients required fusion or revision, and 8 died less than 2 years after implantation, leaving 45 for review. Follow-up was 2 to 13 years. Intervention Total knee replacement with a Guepar II prosthesis. Main outcome measures Radiolucency determined by the Cameron system and clinical scoring using the Hospital for Special Surgery system. Results Of the cemented components, 91% of femoral stems were type IA (no lucency), 9% were type IB (partial lucency), with no type II or III lucency. Tibial lucency was 87% type IA and 13% type IB, with no type II or III lucency. Of the noncemented components, 58% of femoral components were type IA and 42% type IB. Tibial lucency was 71% type IA and 29% type IB. Lucency was mainly present in zones 1 and 2 adjacent to the knee. Clinical rating was 18% excellent, 20% good, 20% fair and 42% poor. Postoperative complications included infection (13%), aseptic loosening (7%), quadriceps lag (16%) and extensor mechanism problems (16%). Conclusions Aseptic loosening is an uncommon problem in hinge total knee replacement. The complication rate in cases of sufficient severity as to require a hinge replacement remains high. Current indications for a hinge prosthesis are anteroposterior instability with a very large flexion gap, complete absence of the collateral ligaments and complete absence of a functioning extensor mechanism. PMID:9267296

  5. Nicotine Replacement Therapy: An Overview

    PubMed Central

    Wadgave, Umesh; Nagesh, L

    2016-01-01

    Today tobacco use is the single greatest preventable cause of death in the world. Tobacco use is often incorrectly perceived to be solely a personal choice. This is contradicted by the fact that when fully aware of the health impact, most tobacco users want to quit but find it difficult to stop due to the addictiveness of nicotine. Henceforth, Nicotine replacement therapy (NRT) came into existence which temporarily replaces much of the nicotine from tobacco to reduce motivation to consume tobacco and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence. Various alternative nicotine sources (gum, transdermal patch, nasal spray, inhaler and sublingual tablets/lozenges) have been incorporated into tobacco cessation programs. Recent research is more focusing on rapid delivery of nicotine (Nicotine preloading, true pulmonary inhaler) and immunological approaches (nicotine vaccine) to tackle nicotine dependence. These NRTs are in general well tolerated and have minimal adverse effects. The review aims to summarize literature on various modes of nicotine replacement therapy methods currently used to treat nicotine dependence, and to give an overview about future possible approaches to treat tobacco use disorder. PMID:27610066

  6. The caudal septum replacement graft.

    PubMed

    Foda, Hossam M T

    2008-01-01

    To describe a technique for reconstructing the lost tip support in cases involving caudal septal and premaxillary deficiencies. The study included 120 patients with aesthetic and functional nasal problems resulting from the loss of caudal septal and premaxillary support. An external rhinoplasty approach was performed to reconstruct the lost support using a cartilaginous caudal septum replacement graft and premaxillary augmentation with Mersilene mesh. The majority of cases (75%) involved revisions in patients who had previously undergone 1 or more nasal surgical procedures. A caudal septum replacement graft was combined with premaxillary augmentation in 93 patients (77.5%). The mean follow-up period was 3 years (range, 1-12 years). The technique succeeded in correcting the external nasal deformities in all patients and resulted in a significant improvement in breathing in 74 patients (86%) with preoperative nasal obstruction. There were no cases of infection, displacement, or extrusion. The caudal septum replacement graft proved to be very effective in restoring the lost tip support in patients with caudal septal deficiency. Combining the graft with premaxillary augmentation using Mersilene mesh helped increase support and stability over long-term follow-up.

  7. VARIANT: Command Line, Web service and Web interface for fast and accurate functional characterization of variants found by Next-Generation Sequencing

    PubMed Central

    Medina, Ignacio; De Maria, Alejandro; Bleda, Marta; Salavert, Francisco; Alonso, Roberto; Gonzalez, Cristina Y.; Dopazo, Joaquin

    2012-01-01

    The massive use of Next-Generation Sequencing (NGS) technologies is uncovering an unexpected amount of variability. The functional characterization of such variability, particularly in the most common form of variation found, the Single Nucleotide Variants (SNVs), has become a priority that needs to be addressed in a systematic way. VARIANT (VARIant ANalyis Tool) reports information on the variants found that include consequence type and annotations taken from different databases and repositories (SNPs and variants from dbSNP and 1000 genomes, and disease-related variants from the Genome-Wide Association Study (GWAS) catalog, Online Mendelian Inheritance in Man (OMIM), Catalog of Somatic Mutations in Cancer (COSMIC) mutations, etc). VARIANT also produces a rich variety of annotations that include information on the regulatory (transcription factor or miRNA-binding sites, etc.) or structural roles, or on the selective pressures on the sites affected by the variation. This information allows extending the conventional reports beyond the coding regions and expands the knowledge on the contribution of non-coding or synonymous variants to the phenotype studied. Contrarily to other tools, VARIANT uses a remote database and operates through efficient RESTful Web Services that optimize search and transaction operations. In this way, local problems of installation, update or disk size limitations are overcome without the need of sacrifice speed (thousands of variants are processed per minute). VARIANT is available at: http://variant.bioinfo.cipf.es. PMID:22693211

  8. US healthcare. America on the line.

    PubMed

    Berliner, H

    1998-01-29

    The growth of telephone advice lines has been partly driven by managed care schemes, keen to reduce use of health services. Some managed care companies are considering e-mail advice services, with nurses responding to descriptions of patients' symptoms.

  9. Immunoglobulin V gene replacement is caused by the intramolecular DNA deletion mechanism.

    PubMed Central

    Usuda, S; Takemori, T; Matsuoka, M; Shirasawa, T; Yoshida, K; Mori, A; Ishizaka, K; Sakano, H

    1992-01-01

    Circular DNA resulting from V gene replacement was studied with an A-MuLV transformed cell line containing ablts. This cell line undergoes V gene replacement at elevated temperatures in the immunoglobulin (Ig) heavy chain (H) gene. Examination of circular DNA revealed that a heptamer-related sequence (TACTGTG) within the coding region of VDJ was joined to the recombination signal sequence (RSS) of a germline VH segment. This provides direct evidence for a intramolecular DNA deletion mechanism for V gene replacement. In the pre-B cell line as well as in in vivo lymphocytes, unusual circular DNAs were found which were structurally similar to the V gene replacement circles. They represented excision products of the deletion type recombination between one complete RSS and a heptamer-like sequence in the Ig H region. PMID:1311252

  10. Fusion following failed total ankle replacement.

    PubMed

    Wünschel, Markus; Leichtle, Ulf G; Leichtle, Carmen I; Walter, Christian; Mittag, Falk; Arlt, Eva; Suckel, Andreas

    2013-04-01

    Although mid- to long-term results after total ankle replacement have improved because of available second- and third-generation devices, failure of total ankle replacement is still more common compared with total hip replacement and total knee replacement. The portfolio of available total ankle replacement revision component options is small. Furthermore, the bone stock of the tibiotalar region is scarce making it difficult and in some situations impossible to perform revision total ankle replacement. In these cases tibiotalar and tibiotalocalcaneal fusions are valuable options. This article describes which surgical procedures should be performed depending on the initial situation and gives detailed advice on surgical technique, postoperative care, and clinical results.

  11. Garan conducts MDCA Reservoir Replacement

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022522 (5 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, services the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station.

  12. Garan conducts MDCA Reservoir Replacement

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022523 (5 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, services the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station.

  13. Garan conducts MDCA Reservoir Replacement

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022531 (5 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, services the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station.

  14. Garan conducts MDCA Reservoir Replacement

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022529 (5 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, services the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station.

  15. Garan conducts MDCA Reservoir Replacement

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022532 (5 May 2011) --- NASA astronaut Ron Garan, Expedition 27 flight engineer, services the Combustion Integrated Rack (CIR) Multi-user Drop Combustion Apparatus (MDCA) in the Destiny laboratory of the International Space Station.

  16. Report: Osteocyte enhancement function of bisphosphonates in prosthetic replacement.

    PubMed

    Yang, Jun; Wang, Shangzeng; Meng, Qingliang; Sun, Yongqiang; Ran, A-fou

    2015-05-01

    Aseptic loosening after prosthetic replacement is the primary cause of shortened service life and lowered stability of prosthesis, and increased revision rate after joint replacement. Factors of causing the loosening of joint prosthesis include mechanical factors and biological factors. The mechanical effect of bisphosphonates (BP) is quite obvious, which can enhance osteocyte function, accelerate the generation of new bone and lower bone resorption activity of osteoclast and macrophage. In animal experiment and adjuvant therapy of patients after joint replacement, BP also shows up the functions of reducing osteolysis induced by wear debris, preventing stress shielding and interface fretting and enhancing bone density. This paper elaborated the mechanism of BP adjusting bone metabolism, and analyzed the action principle and the vital function of it in prosthetic replacement. It has proved that BP can effectively reduce the early peri-prosthesis bone absorption after total hip replacement and improve bone mass peri-prosthesis. It is currently the significant choice of preventing bone lose of peri-prosthesis after operation.

  17. Robotically assisted mitral valve replacement.

    PubMed

    Gao, Changqing; Yang, Ming; Xiao, Cangsong; Wang, Gang; Wu, Yang; Wang, Jiali; Li, Jiachun

    2012-04-01

    In the present study, we determined the safety and efficacy of robotic mitral valve replacement using robotic technology. From January 2007 through March 2011, more than 400 patients underwent various types of robotic cardiac surgery in our department. Of these, 22 consecutive patients underwent robotically assisted mitral valve replacement. Of the 22 patients with isolated rheumatic mitral valve stenosis (9 men and 13 women), the mean age was 44.7 ± 19.8 years (range, 32-65). Preoperatively, all patients underwent a complete workup, including coronary angiography and transthoracic echocardiography. Of the 22 patients, 15 had concomitant atrial fibrillation. The surgical approach was through 4 right-side chest ports with femoral perfusion. Aortic occlusion was performed with a Chitwood crossclamp, and antegrade cardioplegia was administered directly by way of the anterior chest. Using 3 port incisions in the right side of the chest and a 2.5- to 3.0-cm working port, all the procedures were completed with the da Vinci S robot. All patients underwent successful robotic surgery. Of the 22 patients, 16 received a mechanical valve and 6 a tissue valve. The mean cardiopulmonary bypass time and aortic crossclamp time was 137.1 ± 21.9 minutes (range, 105-168) and 99.3 ± 17.9 minutes (range, 80-133), respectively. No operative deaths, stroke, or other complications occurred, and no incisional conversions were required. After surgery, all the patients were followed up echocardiographically. Robotically assisted mitral valve replacement can be performed safely in patients with isolated mitral valve stenosis, and surgical results are excellent. Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  18. Solvent replacement for green processing.

    PubMed Central

    Sherman, J; Chin, B; Huibers, P D; Garcia-Valls, R; Hatton, T A

    1998-01-01

    The implementation of the Montreal Protocol, the Clean Air Act, and the Pollution Prevention Act of 1990 has resulted in increased awareness of organic solvent use in chemical processing. The advances made in the search to find "green" replacements for traditional solvents are reviewed, with reference to solvent alternatives for cleaning, coatings, and chemical reaction and separation processes. The development of solvent databases and computational methods that aid in the selection and/or design of feasible or optimal environmentally benign solvent alternatives for specific applications is also discussed. Images Figure 2 Figure 3 PMID:9539018

  19. Senate committee recommends replacing FEMA

    NASA Astrophysics Data System (ADS)

    Zielinski, Sarah

    2006-05-01

    Flaws in the U.S. Federal Emergency Management Agency (FEMA) that were exposed after Hurricane Katrina struck the U.S. Gulf Coast in August 2005 are too substantial to be fixed, and the agency should be replaced with a more capable structure, recommends a 27 April report released by the Senate Committee on Homeland Security and Government Affairs. ``FEMA is discredited, demoralized, and dysfunctional. It is beyond repair. Just tweaking the organizational chart will not solve the problem,'' said Committee Chair Sen. Susan Collins (R-Maine).

  20. Liver Replacement for Pediatric Patients

    PubMed Central

    Starzl, Thomas E.; Koep, Lawrence J.; Schröter, Gerhard P. J.; Halgrimson, Charles G.; Porter, Kendrick A.; Weil, Richard

    2010-01-01

    Between March 1963 and January 1978, 74 patients 18 years of age or younger have had liver replacements at the University of Colorado Medical Center, Denver. The most common cause of native liver failure was biliary atresia (48/74, 65%); the second most common cause was chronic aggressive hepatitis (12/74, 16%). Twenty-nine patients (39%) lived for at least one year, and 16 are still alive one to nine years after transplantation. Technical surgical problems, rejection, and infection were the main causes of death. Improved immunosuppression is needed; nevertheless, the quality of life in the long-term survivors has encouraged continuation of this difficult work. PMID:377201