A blend of sesame oil and rice bran oil lowers blood pressure and improves the lipid profile in mild-to-moderate hypertensive patients.

PubMed

Devarajan, Sankar; Singh, Ravinder; Chatterjee, Biprabuddha; Zhang, Bo; Ali, Amanat

2016-01-01

Sesame oil and rice bran oil are known for their unsaturated fatty acids and antioxidants contents and have been reported to reduce the cardiovascular risk. To determine the effect of a blend of 20% unrefined cold-pressed lignans-rich sesame oil and 80% physically refined γ-oryzanol-rich rice bran oil (Vivo) as cooking oil in mild-to-moderate hypertensive patients. In this prospective, open-label dietary approach, 300 hypertensive patients and 100 normotensives were divided into groups as: (1) normotensives treated with sesame oil blend, (2) hypertensives treated with sesame oil blend, (3) hypertensives treated with nifedipine, a calcium channel blocker (20 mg/d), and (4) hypertensives receiving the combination of sesame oil blend and nifedipine (20 mg/d). Sesame oil blend was supplied to respective groups, and they were instructed to use it as the only cooking oil for 60 days. Resting blood pressure was measured at days 0, 15, 30, 45, and 60, whereas the fasting lipid profile was measured at days 0 and 60. Significant reduction in blood pressure (systolic, diastolic, and mean arterial) from days 0 to 15, 30, 45, and 60 were observed in hypertensives treated with sesame oil blend alone (P < .001), nifedipine alone (P < .001), and combination of sesame oil blend and nifedipine (P < .001). Sesame oil blend with nifedipine-treated group showed greatest reduction in blood pressure. Total cholesterol, low-density lipoprotein cholesterol, triglycerides, and non-high-density lipoprotein cholesterol levels reduced, whereas high-density lipoprotein cholesterol levels increased significantly only in hypertensives treated with sesame oil blend alone and the combination of sesame oil blend and nifedipine (P < .001). We demonstrate for the first time that using a blend of sesame oil and rice bran oil as cooking oil showed a significant antihypertensive and lipid-lowering action and had noteworthy additive effect with antihypertensive medication. Copyright © 2016 National Lipid Association. Published by Elsevier Inc. All rights reserved.

Children with Special Needs Are VIPs at Sesame Place

ERIC Educational Resources Information Center

Feldscher, Sharla; Stein, Gail

2008-01-01

This article features Sesame Place, the nation's only theme park based entirely on the award-winning television program "Sesame Street" located near Philadelphia, Pennsylvania. Arranged through the Greater Philadelphia Chapter of Variety--The Children's Charity, Sesame Place has hosted over 200,000 guests associated with Variety and…

Variation in Seed Fatty Acid Composition, and Sequence Divergence in the FAD2 Gene Coding Region between Wild and Cultivated Sesame

USDA-ARS?s Scientific Manuscript database

Sesame germplasm harbors genetic diversity which can be useful for sesame improvement in breeding programs. Seven accessions with different levels of oleic acid were selected from the entire USDA sesame germplasm collection (1232 accessions) and planted for morphological observation and re-examinati...

Sesame IO Library User Manual Version 8

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abhold, Hilary; Young, Ginger Ann

This document is a user manual for SES_IO, a low-level library for reading and writing sesame files. The purpose of the SES_IO library is to provide a simple user interface for accessing and creating sesame files that does not change across sesame format type (such as binary, ascii, and xml).

Characterizing the Relationship Between Sesame, Coconut, and Nut Allergy in Children

PubMed Central

Stutius, Lisa M.; Sheehan, William J.; Rangsithienchai, Pitud; Bharmanee, Apinya; Scott, Jordan E.; Young, Michael C.; Dioun, Anahita; Schneider, Lynda C.; Phipatanakul, Wanda

2010-01-01

Sesame and coconut are emerging food allergens in the US. We sought to examine whether children allergic to peanuts and tree nuts are at increased risk of having an allergy to sesame or coconut. We performed a retrospective chart review of children who underwent skin prick testing (SPT) to sesame and coconut and identified 191 children who underwent SPT to sesame and 40 to coconut. Sensitization to sesame was more likely in children with positive SPT to peanuts (odds ratio [OR] = 6.7, 95% confidence interval [CI] [2.7–16.8], P<0.001) and tree nuts (OR = 10.5, 95% CI [4.0–27.7], P<0.001). Children with histories of both peanut and tree nut reaction were more likely to have a history of sesame reaction (OR = 10.2, 95% CI [2.7–38.7], P<0.001). Children with sensitization or allergy to peanuts or tree nuts were not more likely to be sensitized or allergic to coconut. In conclusion, children with peanut or tree nut sensitization were more likely to be sensitized to sesame but not coconut. Children with clinical histories of both peanut and tree nut allergy were more likely to be allergic to sesame. PMID:21073539

Anti-atherosclerotic and anti-inflammatory actions of sesame oil.

PubMed

Narasimhulu, Chandrakala Aluganti; Selvarajan, Krithika; Litvinov, Dmitry; Parthasarathy, Sampath

2015-01-01

Atherosclerosis, a major form of cardiovascular disease, has now been recognized as a chronic inflammatory disease. Nonpharmacological means of treating chronic diseases have gained attention recently. We previously reported that sesame oil has anti-atherosclerotic properties. In this study, we have determined the mechanisms by which sesame oil might modulate atherosclerosis by identifying genes and inflammatory markers. Low-density lipoprotein receptor knockout (LDLR(-/-)) female mice were fed with either an atherogenic diet or an atherogenic diet reformulated with sesame oil (sesame oil diet). Plasma lipids and atherosclerotic lesions were quantified after 3 months of feeding. Plasma samples were used for cytokine analysis. RNA was extracted from the liver tissue and used for global gene arrays. The sesame oil diet significantly reduced atherosclerotic lesions, plasma cholesterol, triglyceride, and LDL cholesterol levels in LDLR(-/-) mice. Plasma inflammatory cytokines, such as MCP-1, RANTES, IL-1α, IL-6, and CXCL-16, were significantly reduced, demonstrating an anti-inflammatory property of sesame oil. Gene array analysis showed that sesame oil induced many genes, including ABCA1, ABCA2, APOE, LCAT, and CYP7A1, which are involved in cholesterol metabolism and reverse cholesterol transport. In conclusion, our studies suggest that a sesame oil-enriched diet could be an effective nonpharmacological treatment for atherosclerosis by controlling inflammation and regulating lipid metabolism.

Genome-wide analysis of WRKY gene family in the sesame genome and identification of the WRKY genes involved in responses to abiotic stresses.

PubMed

Li, Donghua; Liu, Pan; Yu, Jingyin; Wang, Linhai; Dossa, Komivi; Zhang, Yanxin; Zhou, Rong; Wei, Xin; Zhang, Xiurong

2017-09-11

Sesame (Sesamum indicum L.) is one of the world's most important oil crops. However, it is susceptible to abiotic stresses in general, and to waterlogging and drought stresses in particular. The molecular mechanisms of abiotic stress tolerance in sesame have not yet been elucidated. The WRKY domain transcription factors play significant roles in plant growth, development, and responses to stresses. However, little is known about the number, location, structure, molecular phylogenetics, and expression of the WRKY genes in sesame. We performed a comprehensive study of the WRKY gene family in sesame and identified 71 SiWRKYs. In total, 65 of these genes were mapped to 15 linkage groups within the sesame genome. A phylogenetic analysis was performed using a related species (Arabidopsis thaliana) to investigate the evolution of the sesame WRKY genes. Tissue expression profiles of the WRKY genes demonstrated that six SiWRKY genes were highly expressed in all organs, suggesting that these genes may be important for plant growth and organ development in sesame. Analysis of the SiWRKY gene expression patterns revealed that 33 and 26 SiWRKYs respond strongly to waterlogging and drought stresses, respectively. Changes in the expression of 12 SiWRKY genes were observed at different times after the waterlogging and drought treatments had begun, demonstrating that sesame gene expression patterns vary in response to abiotic stresses. In this study, we analyzed the WRKY family of transcription factors encoded by the sesame genome. Insight was gained into the classification, evolution, and function of the SiWRKY genes, revealing their putative roles in a variety of tissues. Responses to abiotic stresses in different sesame cultivars were also investigated. The results of our study provide a better understanding of the structures and functions of sesame WRKY genes and suggest that manipulating these WRKYs could enhance resistance to waterlogging and drought.

SESAME 7363: A new Li(6)D equation of state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheppard, Daniel Glen; Kress, Joel David; Crockett, Scott

2015-09-21

A new Equation of State (EOS) for Lithium 6 Deuteride ( 6LiD) was created, sesame 7363. This EOS was released to the user community under “eos-developmental” as sesame 97363. The construction of this new EOS is a modification of a previously released EOS, sesame 7360 1. Sesame 7360 is too stiff (5-10% excess pressure) at high compressions and high temperatures (ρ = 4-110g/cm 3, T = 30-10,000 eV) compared to orbital-free density-functional theory. Sesame 7363 is softer and gives a better representation of the physics over this range without compromising the agreement with the experimental and simulation data that sesamemore » 7360 was based on.« less

The Healing Effect of Sesame Oil, Camphor and Honey on Second Degree Burn Wounds in Rat.

PubMed

Vaghardoost, Reza; Mousavi Majd, Seyed GholamReza; Tebyanian, Hamid; Babavalian, Hamid; Malaei, Leila; Niazi, Mitra; Javdani, Ali

2018-01-01

Many studies were carried out to improve sophisticated dressings to accelerate healing processes and reduce the microbial burden in burn wounds. This study evaluated the healing effect of herbal ointment containing extract of sesame oil, camphor and honey on second degree burn wounds in rats in comparison with daily dressing oil vaseline. Forty rats were randomly assigned to two equal groups. A deep second degree burn was formed on the back of each rat with using a standard burning technique. The burns were dressed daily with herbal ointment containing extract of sesame oil, camphor and honey in group 1, dressing oil vaseline in group 2. The response to treatment was evaluated by digital photography during the treatment on 0, 7, 14, 21, 28 days. Histological scoring was undertaken for scar tissue samples on 0, 7, 14, 21, 28 days. Considerable epithelization in the herbal ointment group vs. the control group over the study period was noted. Neovascularization was significantly higher in herbal ointment treated rats as well. In terms of difference of wound surface area, maximal healing was noticed in herbal ointment extract of sesame oil, camphor and honey group and the minimal repair in the control group. The greatest rate of healing was in the herbal ointment group containing sesame oil, camphor and honey, so the herbal ointment as a suitable substitute for dressing and healing of burn wound injuries is recommended.

The Healing Effect of Sesame Oil, Camphor and Honey on Second Degree Burn Wounds in Rat

PubMed Central

Vaghardoost, Reza; Mousavi Majd, Seyed GholamReza; Tebyanian, Hamid; Babavalian, Hamid; Malaei, Leila; Niazi, Mitra; Javdani, Ali

2018-01-01

BACKGROUND Many studies were carried out to improve sophisticated dressings to accelerate healing processes and reduce the microbial burden in burn wounds. This study evaluated the healing effect of herbal ointment containing extract of sesame oil, camphor and honey on second degree burn wounds in rats in comparison with daily dressing oil vaseline. METHODS Forty rats were randomly assigned to two equal groups. A deep second degree burn was formed on the back of each rat with using a standard burning technique. The burns were dressed daily with herbal ointment containing extract of sesame oil, camphor and honey in group 1, dressing oil vaseline in group 2. The response to treatment was evaluated by digital photography during the treatment on 0, 7, 14, 21, 28 days. Histological scoring was undertaken for scar tissue samples on 0, 7, 14, 21, 28 days. RESULTS Considerable epithelization in the herbal ointment group vs. the control group over the study period was noted. Neovascularization was significantly higher in herbal ointment treated rats as well. In terms of difference of wound surface area, maximal healing was noticed in herbal ointment extract of sesame oil, camphor and honey group and the minimal repair in the control group. CONCLUSION The greatest rate of healing was in the herbal ointment group containing sesame oil, camphor and honey, so the herbal ointment as a suitable substitute for dressing and healing of burn wound injuries is recommended. PMID:29651394

Voluntarias De Sesame Street: Manual Para Conducir Las Sesiones "Sesame Street" Con Ninos De Edad Pre-Escolar.

ERIC Educational Resources Information Center

Filep, Robert T.; And Others

This guide was prepared to aid Spanish-speaking volunteers working with preschool children before, during, and after viewing the television program, "Sesame Street". The text is written in Spanish. Suggestions in this booklet grew out of a study called the Sesame Mother Pilot Project conducted in 1970-71 by the Institute for Educational…

Detection and quantification of adulteration of sesame oils with vegetable oils using gas chromatography and multivariate data analysis.

PubMed

Peng, Dan; Bi, Yanlan; Ren, Xiaona; Yang, Guolong; Sun, Shangde; Wang, Xuede

2015-12-01

This study was performed to develop a hierarchical approach for detection and quantification of adulteration of sesame oil with vegetable oils using gas chromatography (GC). At first, a model was constructed to discriminate the difference between authentic sesame oils and adulterated sesame oils using support vector machine (SVM) algorithm. Then, another SVM-based model is developed to identify the type of adulterant in the mixed oil. At last, prediction models for sesame oil were built for each kind of oil using partial least square method. To validate this approach, 746 samples were prepared by mixing authentic sesame oils with five types of vegetable oil. The prediction results show that the detection limit for authentication is as low as 5% in mixing ratio and the root-mean-square errors for prediction range from 1.19% to 4.29%, meaning that this approach is a valuable tool to detect and quantify the adulteration of sesame oil. Copyright © 2015 Elsevier Ltd. All rights reserved.

Results of the Study on the Role and Penetration of Sesame Street and the Electric Company in Ghetto Communities.

ERIC Educational Resources Information Center

Children's Television Workshop, New York, NY.

The findings of a 1973 study covering the performance of Sesame Street and The Electric Company in ghetto communities are reported briefly. The steps taken to repeat the methodology of earlier Sesame Street studies are described. Data are given on: penetration of Sesame Street among preschool children in Bedford Stuyvesant, East Harlem, Chicago,…

Energy analysis of convectively induced wind perturbations

NASA Technical Reports Server (NTRS)

Fuelberg, Henry E.; Buechler, Dennis E.

1989-01-01

Budgets of divergent and rotational components of kinetic energy (KD and KR) are examined for four upper level wind speed maxima that develop during the fourth Atmospheric Variability Experiment (AVE IV) and the first AVE-Severe Environmental Storms and Mesoscale Experiment (AVE-SESAME I). A similar budget analysis is performed for a low-level jet stream during AVE-SESAME I. The energetics of the four upper level speed maxima is found to have several similarities. The dominant source of KD is cross-contour flow by the divergent wind, and KD provides a major source of KR via a conversion process. Conversion from available potential energy provides an additional source of KR in three of the cases. Horizontal maps reveal that the conversions involving KD are maximized in regions poleward of the convection. Low-level jet development during AVE-SESAME I appears to be assisted by convective activity to the west.

Assessment of aflatoxigenic Aspergillus and other fungi in millet and sesame from Plateau State, Nigeria

PubMed Central

Ezekiel, C.N.; Udom, I.E.; Frisvad, J.C.; Adetunji, M.C.; Houbraken, J.; Fapohunda, S.O.; Samson, R.A.; Atanda, O.O.; Agi-Otto, M.C.; Onashile, O.A.

2014-01-01

Sixteen fonio millet and 17 sesame samples were analysed for incidence of moulds, especially aflatoxigenic Aspergillus species, in order to determine the safety of both crops to consumers, and to correlate aflatoxin levels in the crops with levels produced by toxigenic isolates on laboratory medium. Diverse moulds including Alternaria, Aspergillus, Cercospora, Fusarium, Mucor, Penicillium, Rhizopus and Trichoderma were isolated. Aspergillus was predominantly present in both crops (46–48%), and amongst the potentially aflatoxigenic Aspergillus species, A. flavus recorded the highest incidence (68% in fonio millet; 86% in sesame kernels). All A. parvisclerotigenus isolates produced B and G aflatoxins in culture while B aflatoxins were produced by only 39% and 20% of A. flavus strains isolated from the fonio millet and sesame kernels, respectively. Aflatoxin concentrations in fonio millet correlated inversely (r = −0.55; p = 0.02) with aflatoxin levels produced by toxigenic isolates on laboratory medium, but no correlation was observed in the case of the sesame samples. Both crops, especially sesame, may not be suitable substrates for aflatoxin biosynthesis. This is the first report on A. parvisclerotigenus in sesame. PMID:24772370

OpenSesame: an open-source, graphical experiment builder for the social sciences.

PubMed

Mathôt, Sebastiaan; Schreij, Daniel; Theeuwes, Jan

2012-06-01

In the present article, we introduce OpenSesame, a graphical experiment builder for the social sciences. OpenSesame is free, open-source, and cross-platform. It features a comprehensive and intuitive graphical user interface and supports Python scripting for complex tasks. Additional functionality, such as support for eyetrackers, input devices, and video playback, is available through plug-ins. OpenSesame can be used in combination with existing software for creating experiments.

Identification of a characteristic antioxidant, anthrasesamone F, in black sesame seeds and its accumulation at different seed developmental stages.

PubMed

Furumoto, Toshio; Nishimoto, Kiyoshi

2016-01-01

Assay-guided fractionation of the methanol extract from black seeds of sesame (Sesamum indicum L.) led to the isolation of an active compound that had a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity. This antioxidant was confirmed to be anthrasesamone F, an anthraquinone derivative previously isolated from different black sesame seeds and biogenetically related to other anthrasesamones in sesame roots. The radical scavenging assay showed that anthrasesamone F had more potent activity than Trolox. The content of anthrasesamone F in different parts and at different developmental stages of black sesame seeds was investigated to clarify the accumulation pattern of this antioxidant in the black seeds. Anthrasesamone F was localized in the seed coat of black seeds and accumulated after the seed coat color changed to black. The content of anthrasesamone F increased gradually with seed maturation and drastically on air-drying, the final stage in sesame cultivation.

SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

NASA Astrophysics Data System (ADS)

U˝Lkü, Dinçer; Rahighi, Javad; Winick, Herman

2007-01-01

SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference ~133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.

SESAME — A 3rd Generation Synchrotron Light Source for the Middle East

NASA Astrophysics Data System (ADS)

Å°lkü, Dinçer; Rahighi, Javad; Winick, Herman

2007-01-01

SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference ˜133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.

SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulkue, Dincer; Rahighi, Javad; Winick, Herman

2007-01-19

SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK,more » and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference {approx}133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member countries. Additional funds to purchase components of the new ring and beamlines are being sought from the EU, the US, and other sources. SESAME has benefited greatly from offers by other light source facilities of equipment and training fellowships in both accelerator technology and applications of synchrotron radiation. Details of this, and other aspects of the training program, are given below. It is hoped that in the future fellowship offers will continue to be made by many light source laboratories to further increase the level of experience with accelerator technology and synchrotron light science in preparation for the start of operation of SESAME.« less

A Blend of Sesame and Rice Bran Oils Lowers Hyperglycemia and Improves the Lipids.

PubMed

Devarajan, Sankar; Chatterjee, Biprabuddha; Urata, Hidenori; Zhang, Bo; Ali, Amanat; Singh, Ravinder; Ganapathy, Sambandam

2016-07-01

Considering the health benefits of sesame oil and rice bran oil, the study was conducted to determine the extent to which the daily use of this blend of oils controls hyperglycemia and improves the lipid profile. In this 8-week open-label randomized dietary intervention study, 300 type 2 diabetes mellitus patients and 100 normoglycemic subjects were grouped as 1) normoglycemic subjects (n = 100) treated with sesame oil blend Vivo (Adani Wilmar, Ahmedabad, Gujarat, India), 2) type 2 diabetes mellitus patients treated with sesame oil blend (n = 100), 3) type 2 diabetes mellitus patients treated with glibenclamide (n = 100; 5 mg/d), and 4) type 2 diabetes mellitus patients treated in combination of glibenclamide (5 mg/d) and sesame oil blend (n = 100). Twelve-hour fasting blood glucose, glycated hemoglobin (HbA1c), and lipid profile followed by postprandial blood glucose were measured at baseline. Sesame oil blend was supplied to the respective groups, who were instructed to use as cooking oil for 8 weeks. Fasting and postprandial blood glucose was measured at week 4 and week 8, while HbA1c and lipid profile were measured at week 8. At week 4 and week 8, type 2 diabetes mellitus patients treated with sesame oil blend or glibenclamide or combination of glibenclamide and sesame oil blend showed significant reduction of fasting and postprandial blood glucose (P <.001). HbA1c, total cholesterol, triglycerides, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol were significantly reduced (P <.001), while high-density lipoprotein cholesterol was significantly increased at week 8 (P <.001) in type 2 diabetes mellitus patients treated with the sesame oil blend or combination of glibenclamide and sesame oil blend; whereas glibenclamide-alone-treated type 2 diabetes mellitus patients showed a significant reduction of HbA1c (P <.001) only. A novel blend of 20% cold-pressed unrefined sesame oil and 80% physically refined rice bran oil as cooking oil, lowered hyperglycemia and improved the lipid profile in type 2 diabetes mellitus patients. Copyright © 2016 Elsevier Inc. All rights reserved.

A preliminary look at AVE-SESAME 2 conducted on 19-20 April 1979

NASA Technical Reports Server (NTRS)

Williams, S. F.; Horvath, N.; Turner, R. E.

1980-01-01

Preliminary information on data collected, synoptic conditions, and severe and unusual weather reported during the AVE-SESAME 2 period is presented. The information provides researchers a preliminary look at conditions during the AVE-SESAME 2 period.

Sesame allergy: current perspectives.

PubMed

Adatia, Adil; Clarke, Ann Elaine; Yanishevsky, Yarden; Ben-Shoshan, Moshe

2017-01-01

Sesame is an important global allergen affecting ~0.1% of the North American population. It is a major cause of anaphylaxis in the Middle East and is the third most common food allergen in Israel. We conducted a systematic review of original articles published in the last 10 years regarding the diagnosis and management of sesame allergy. Skin prick testing appears to be a useful predictor of sesame allergy in infants, although data are less consistent in older children and adults. The diagnostic capacity of serum-specific immunoglobulin E is poor, especially in studies that used oral food challenges to confirm the diagnosis. Double-blind, placebo-controlled food challenge thus remains the diagnostic gold standard for sesame allergy. The cornerstone of sesame allergy management is allergen avoidance, though accidental exposures are common and patients must be prepared to treat the consequent reactions with epinephrine. Novel diagnostic and treatment options such as component-resolved diagnostics, basophil activation testing, and oral immunotherapy are under development but are not ready for mainstream clinical application.

Effects of dietary sesame oil on growth performance, chemical composition, lipid oxidation, and sensory characteristics of rainbow trout Oncorhynchus mykiss.

PubMed

Hematzadeh, Azar; Ali Jalali, Sayed Mohamad

2017-09-28

The present study, the effects of dietary sesame oil (SO) on growth performance and fillet composition of rainbow trout (Oncorhynchus mykiss) were investigated. Twenty-five fish were randomly allocated in three groups by three replication, in mean initial weight 53.3 g in each tank. Experimental diets consisted of fish oil (FO), sesame oil (SO) and 1:1 blends of two oils, fish oil and sesame oil (FOSO). Dietary sesame oil had no significant effect on growth rate or feed conversion ratio. Similarly, no significant differences were observed between dietary treatments for ash content in fillet of fish. The fillet lipid content was lower in fish fed by sesame oil, but the moisture and the protein were higher. Furthermore, Thiobarbituric acid (TBA) test was changed in different groups and it was lower in SO. The organoleptic indices were affected by dietary oils and FO group had more fishy flavour.

Sesame oil mitigates nutritional steatohepatitis via attenuation of oxidative stress and inflammation: a tale of two-hit hypothesis.

PubMed

Periasamy, Srinivasan; Chien, Se-Ping; Chang, Po-Cheng; Hsu, Dur-Zong; Liu, Ming-Yie

2014-02-01

Nonalcoholic fatty liver disease, the most common chronic liver disorder worldwide, comprises conditions from steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. NASH is associated with an increased risk of hepatocellular carcinoma. Sesame oil, a healthful food, increases resistance to oxidative stress, inflammation and protects against multiple organ injury in various animal models. We investigated the protective effect of sesame oil against nutritional steatohepatitis in mice. C57BL/6 J mice were fed with methionine-choline deficient (MCD) diet for 28 days to induce NASH. Sesame oil (1 and 2 ml/kg) was treated from 22nd to 28th day. Body weight, steatosis, triglycerides, aspartate transaminase, alanine transaminase, nitric oxide, malondialdehyde, tumor necrosis factor-α, interlukin-6, interleukin-1β, leptin, and transforming growth factor-β1 (TGF-β1) were assessed after 28 days. All tested parameters were higher in MCD-fed mice than in normal control mice. Mice fed with MCD diet for 4 weeks showed severe liver injury with steatosis, oxidative stress, and necrotic inflammation. In sesame-oil-treated mice, all tested parameters were significantly attenuated compared with MCD-alone mice. Sesame oil inhibited oxidative stress, inflammatory cytokines, leptin, and TGF-β1 in MCD-fed mice. In addition, histological analysis showed that sesame oil provided significant protection against fibrotic collagen. We conclude that sesame oil protects against steatohepatitic fibrosis by decreasing oxidative stress, inflammatory cytokines, leptin and TGF-β1. Copyright © 2014 Elsevier Inc. All rights reserved.

AVE-SESAME IV: 25 mb sounding data

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.; Gilchrist, L. P.; Turner, R. E.

1980-01-01

The rawinsonde sounding program for the AVE-SESAME 4 experiment is descirbed and tabulated data at 25 mb for the 23 National Weather Service and 20 special stations participating in the experiment are presented. Soundings were taken at 3 hr intervals beginning at 1200 GMT on May 9, 1979, and ending at 1200 GMT on May 10, 1979 (nine sounding times). The method of processing is discussed, estimates of the rms errors in the data are presented, and an example of contact data is given. Reasons are given for the termination of soundings below 100 mb, and soundings are listed which exhibit abnormal characteristics.

Utilization of the Fine Particles Obtained from Cold Pressed Vegetable Oils: A Case Study in Organic Rice Bran, Sunflower and Sesame Oils.

PubMed

Srikaeo, Khongsak; Poungsampao, Phuttan; Phuong, Nguyen Thi

2017-01-01

Fine particles obtained from the physical refining of organic cold pressed vegetable oils which are normally discarded as a process waste can be utilized as cosmetic and food ingredients. This paper demonstrated the use of the fine particles from rice bran (Thai Jasmine and Riceberry varieties), sunflower and sesame oils as the ingredient in body mask and as dietary fiber. It was found that the fine particles from rice brans exhibited better antioxidant properties than those of sunflower and sesame. The mixed fine particles were added to body mask formula. The addition of the fine particles affected the physical properties and stability of the body mask especially viscosity and pH. Total dietary fiber recovered from the fine particles ranged from 17.91-23.83 g/100g dry sample. Dietary fiber from Riceberry exhibited the best antioxidant properties as evidenced by DPPH radical scavenging activity and reducing power.

Technical note: Equilibrium moisture content of kabuli chickpea, black sesame, and white sesame seeds

USDA-ARS?s Scientific Manuscript database

Sesame and chickpeas are important crops for Ethiopia as both are major exports providing small farmers and the country much revenue. There is a lack of information on fundamental equilibrium moisture content (EMC) relationships for these products which would help facilitate better monitoring and st...

Sesame Street PEP Handbook. Second Edition.

ERIC Educational Resources Information Center

Children's Television Workshop, New York, NY.

This handbook for early childhood educators describes the Sesame Street PEP, an educational enrichment program for 3- to 5-year-olds that makes learning a fun and challenging adventure by using the educational goals of the Sesame Street show, children's books, and developmentally appropriate activities. This program seeks to: (1) stimulate…

InP/InGaP quantum-dot SESAM mode-locked Alexandrite laser

NASA Astrophysics Data System (ADS)

Ghanbari, Shirin; Fedorova, Ksenia A.; Krysa, Andrey B.; Rafailov, Edik U.; Major, Arkady

2018-02-01

A semiconductor saturable absorber mirror (SESAM) passively mode-locked Alexandrite laser was demonstrated. Using an InP/InGaP quantum-dot saturable absorber mirror, pulse duration of 420 fs at 774 nm was obtained. The laser was pumped at 532 nm and generated 325 mW of average output power in mode-locked regime with a pump power of 7.12 W. To the best of our knowledge, this is the first report of a passively mode-locked Alexandrite laser using SESAM in general and quantum-dot SESAM in particular.

Simultant encapsulation of vitamin C and beta-carotene in sesame (Sesamum indicum l.) liposomes

NASA Astrophysics Data System (ADS)

Hudiyanti, D.; Fawrin, H.; Siahaan, P.

2018-04-01

In this study sesame liposomes were used to encapsulate both vitamin C and beta-carotene simultaneously. Liposomes were prepared with addition of cholesterol. The encapsulation efficiency (EE) of sesame liposomes for vitamin C in the present of beta-carotene was 77%. The addition of cholesterol increased the encapsulation efficiency. The highest encapsulation efficiency was 89% obtained in liposomes with 10% and 20% cholesterol. Contrary to that, the highest beta-carotene encapsulation efficiency of 78%, was found in the sesame liposomes prepared without the added cholesterol. Results showed that sesame liposomes can be used to encapsulate beta-carotene and vitamin C simultaneously. When beta-carotene and vitamin C were encapsulated concurrently, cholesterol intensified the efficiency of vitamin C encapsulation on the contrary it diminished the efficiency of beta-carotene encapsulation.

Enduring amnesia induced by ICV scopolamine is reversed by sesame oil in male rats.

PubMed

Tabari, Shabnam-Sadat Seyedi; Babri, Shirin; Mirzaie, Fariba; Farajdokht, Fereshteh; Mohaddes, Gisou

2016-08-01

To evaluated the long-term effect of scopolamine and sesame oil on spatial memory. Memory impairment induced by Intracerebroventricular (ICV) injection of scopolamine hydrochloride (10 μg/ rat). Animals were gavaged for 4 weeks with saline, sesame oil (0.5, 1, or 2 mL/kg/day), or 3 weeks with memantine (30 mg/kg/day) in advance to induction of amnesia. Morris water maze (MWM) test was conducted 6 days after microinjection of scopolamine. Then, blood and brain samples were collected and evaluated for the malondialdehyde (MDA) levels, superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities, and total antioxidant status (TAS) and ferric reducing ability of plasma (FRAP). Scopolamine significantly decreased traveled distance and time spent in target quadrant in probe test. Pretreatment of rats with sesame oil (0.5 mg/kg) mitigated scopolamine-induced behavioral alterations. Measurement of MDA, SOD, and GPX in brain tissue, and FRAP and TAS in blood showed little changes in animals which had received scopolamine or sesame oil. Intracerebroventricular injection of scopolamine has a residual effect on memory after six days. Sesame oil has an improving effect on spatial memory; however this effect is possibly mediated by mechanisms other than antioxidant effect of sesame oil.

The Emerging Oilseed Crop Sesamum indicum Enters the “Omics” Era

PubMed Central

Dossa, Komivi; Diouf, Diaga; Wang, Linhai; Wei, Xin; Zhang, Yanxin; Niang, Mareme; Fonceka, Daniel; Yu, Jingyin; Mmadi, Marie A.; Yehouessi, Louis W.; Liao, Boshou; Zhang, Xiurong; Cisse, Ndiaga

2017-01-01

Sesame (Sesamum indicum L.) is one of the oldest oilseed crops widely grown in Africa and Asia for its high-quality nutritional seeds. It is well adapted to harsh environments and constitutes an alternative cash crop for smallholders in developing countries. Despite its economic and nutritional importance, sesame is considered as an orphan crop because it has received very little attention from science. As a consequence, it lags behind the other major oil crops as far as genetic improvement is concerned. In recent years, the scenario has considerably changed with the decoding of the sesame nuclear genome leading to the development of various genomic resources including molecular markers, comprehensive genetic maps, high-quality transcriptome assemblies, web-based functional databases and diverse daft genome sequences. The availability of these tools in association with the discovery of candidate genes and quantitative trait locis for key agronomic traits including high oil content and quality, waterlogging and drought tolerance, disease resistance, cytoplasmic male sterility, high yield, pave the way to the development of some new strategies for sesame genetic improvement. As a result, sesame has graduated from an “orphan crop” to a “genomic resource-rich crop.” With the limited research teams working on sesame worldwide, more synergic efforts are needed to integrate these resources in sesame breeding for productivity upsurge, ensuring food security and improved livelihood in developing countries. This review retraces the evolution of sesame research by highlighting the recent advances in the “Omics” area and also critically discusses the future prospects for a further genetic improvement and a better expansion of this crop. PMID:28713412

Multiplex Real-Time qPCR Assay for Simultaneous and Sensitive Detection of Phytoplasmas in Sesame Plants and Insect Vectors

PubMed Central

Ikten, Cengiz; Ustun, Rustem; Catal, Mursel; Yol, Engin; Uzun, Bulent

2016-01-01

Phyllody, a destructive and economically important disease worldwide caused by phytoplasma infections, is characterized by the abnormal development of floral structures into stunted leafy parts and contributes to serious losses in crop plants, including sesame (Sesamum indicum L.). Accurate identification, differentiation, and quantification of phyllody-causing phytoplasmas are essential for effective management of this plant disease and for selection of resistant sesame varieties. In this study, a diagnostic multiplex qPCR assay was developed using TaqMan® chemistry based on detection of the 16S ribosomal RNA gene of phytoplasmas and the 18S ribosomal gene of sesame. Phytoplasma and sesame specific primers and probes labeled with different fluorescent dyes were used for simultaneous amplification of 16SrII and 16SrIX phytoplasmas in a single tube. The multiplex real-time qPCR assay allowed accurate detection, differentiation, and quantification of 16SrII and 16SrIX groups in 109 sesame plant and 92 insect vector samples tested. The assay was found to have a detection sensitivity of 1.8 x 102 and 1.6 x 102 DNA copies for absolute quantification of 16SrII and 16SrIX group phytoplasmas, respectively. Relative quantification was effective and reliable for determination of phyllody phytoplasma DNA amounts normalized to sesame DNA in infected plant tissues. The development of this qPCR assay provides a method for the rapid measurement of infection loads to identify resistance levels of sesame genotypes against phyllody phytoplasma disease. PMID:27195795

Genome sequencing of the high oil crop sesame provides insight into oil biosynthesis

PubMed Central

2014-01-01

Background Sesame, Sesamum indicum L., is considered the queen of oilseeds for its high oil content and quality, and is grown widely in tropical and subtropical areas as an important source of oil and protein. However, the molecular biology of sesame is largely unexplored. Results Here, we report a high-quality genome sequence of sesame assembled de novo with a contig N50 of 52.2 kb and a scaffold N50 of 2.1 Mb, containing an estimated 27,148 genes. The results reveal novel, independent whole genome duplication and the absence of the Toll/interleukin-1 receptor domain in resistance genes. Candidate genes and oil biosynthetic pathways contributing to high oil content were discovered by comparative genomic and transcriptomic analyses. These revealed the expansion of type 1 lipid transfer genes by tandem duplication, the contraction of lipid degradation genes, and the differential expression of essential genes in the triacylglycerol biosynthesis pathway, particularly in the early stage of seed development. Resequencing data in 29 sesame accessions from 12 countries suggested that the high genetic diversity of lipid-related genes might be associated with the wide variation in oil content. Additionally, the results shed light on the pivotal stage of seed development, oil accumulation and potential key genes for sesamin production, an important pharmacological constituent of sesame. Conclusions As an important species from the order Lamiales and a high oil crop, the sesame genome will facilitate future research on the evolution of eudicots, as well as the study of lipid biosynthesis and potential genetic improvement of sesame. PMID:24576357

The Emerging Oilseed Crop Sesamum indicum Enters the "Omics" Era.

PubMed

Dossa, Komivi; Diouf, Diaga; Wang, Linhai; Wei, Xin; Zhang, Yanxin; Niang, Mareme; Fonceka, Daniel; Yu, Jingyin; Mmadi, Marie A; Yehouessi, Louis W; Liao, Boshou; Zhang, Xiurong; Cisse, Ndiaga

2017-01-01

Sesame ( Sesamum indicum L.) is one of the oldest oilseed crops widely grown in Africa and Asia for its high-quality nutritional seeds. It is well adapted to harsh environments and constitutes an alternative cash crop for smallholders in developing countries. Despite its economic and nutritional importance, sesame is considered as an orphan crop because it has received very little attention from science. As a consequence, it lags behind the other major oil crops as far as genetic improvement is concerned. In recent years, the scenario has considerably changed with the decoding of the sesame nuclear genome leading to the development of various genomic resources including molecular markers, comprehensive genetic maps, high-quality transcriptome assemblies, web-based functional databases and diverse daft genome sequences. The availability of these tools in association with the discovery of candidate genes and quantitative trait locis for key agronomic traits including high oil content and quality, waterlogging and drought tolerance, disease resistance, cytoplasmic male sterility, high yield, pave the way to the development of some new strategies for sesame genetic improvement. As a result, sesame has graduated from an "orphan crop" to a "genomic resource-rich crop." With the limited research teams working on sesame worldwide, more synergic efforts are needed to integrate these resources in sesame breeding for productivity upsurge, ensuring food security and improved livelihood in developing countries. This review retraces the evolution of sesame research by highlighting the recent advances in the "Omics" area and also critically discusses the future prospects for a further genetic improvement and a better expansion of this crop.

[Care for elderly patients in Africa: Analysis of the financial implications of the SESAME plan on the budget of the regional hospital center in Thies, Senegal].

PubMed

Faye, A; Diousse, P; Seck, I; Diongue, M; Ndiaye, P; Diagne-Camara, M; Tal-Dia, A; Dia, La

2010-04-01

The SESAME plan has been implemented at the Thies Regional Hospital Center (TRHC) for one year. The purpose of this study was to analyze the financial implications of the plan on the hospital budget for the sustainability of care for persons aged 60 and over. This descriptive study included analysis of budget data from October 2006 to September 2007 plus information obtained by interviewing the accountant and head of SESAME plan. The number of patients managed, sources of CHRT funding, grants from various SESAME plan partners, and expenditures for each partner were determined. The weight of the SESAME plan in the CHRT operating budget was determined by calculating the ratio of the overall cost of care for elderly persons in relation to the hospital's revenues and SESAME grants. During the study period, the CHRT received a total of 17375 elderly persons including 89% with no pension or social security. The institute pension scheme (IPRES) covered 21% of the plan as compared to 79% for the state. Utilization plan grants in relation to funding source was 41% for IPRES and 124% for the State. The total cost of services provided to beneficiaries of the SESAME plan exceeded the aggregate amount by 26 083 847 CFA francs. The weight of the SESAME plan in the operating cost of the CHRT was 17%. Prefinancing a plan to cover elderly care in hospitals should be sufficient to prevent deficits from impacting negatively on the operating budget of the hospital.

The Role of "Kilimani Sesame" in the Healthy Development of Tanzanian Preschool Children

ERIC Educational Resources Information Center

Borzekowski, Dina L. G.; Macha, Jacob E.

2010-01-01

"Kilimani Sesame," a media intervention that employs print, radio, and television, was developed to entertain and educate preschool children in Tanzania. This study examined the effects of a six-week intervention delivering "Kilimani Sesame" material to 223 children in the rural district of Kisarawe and the city of Dar es…

Sesame Street Research: A 20th Anniversary Symposium (Princeton, New Jersey, November 4, 1989).

ERIC Educational Resources Information Center

Mann, Peter B., Ed.

A research agenda has been at the core of "Sesame Street" and other Children's Television Workshop (CTW) educational projects since inception. This collection of presentations, from a symposium honoring the twentieth anniversary of Sesame Street's debut on national television, addresses research's role in the series, describing how…

An Analysis of “Natural” Food Litigation to Build a Sesame Allergy Consumer Class Action.

PubMed

Shaker, Dana

In a world where food allergy is still an incurable disease, law and regulation stand as necessary mechanisms to provide food-allergic consumers with the information they need to protect their health. The Food Allergen Labeling and Consumer Protection Act of 2004 provided specific labeling requirements for the “Top Eight” allergens in the U.S.: milk, soy, gluten, egg, tree nut, peanut, fish, and Crustacean shellfish. Since then, sesame has become more prevalent as an allergen and remains just as dangerous, inducing anaphylactic shock in some sesame-allergic individuals. Yet sesame remains unregulated, despite advocates and congressional members arguing for its inclusion. This note entertains one solution to this problem by exploring the most strategic way to bring a sesame allergy class action against a private food company under California’s consumer protection statutes. Because this kind of class action does not have much, if any, precedent, this note analyzes the basic, preliminary issues that any litigant would have to navigate around to certify a class, including preemption, standing, and the claim itself, by focusing on how courts have examined these issues in the recent “natural” class action litigation. It also analyzes the legal, moral, and practical aspects of choosing a type of relief, as well as whom to include in the class. Finally, this note briefly considers how FDA itself can ensure sesame is regulated on the labels of food products, given that some of the legal issues may well be insurmountable for this particular class action. This note explores the potential solutions to difficult legal hurdles in constructing a sesame allergy class action, arguing that litigating a sesame allergy class action—even if it is not ultimately successful—could start a productive conversation that might lead Congress or FDA to provide greater public health and consumer protection for those with sesame allergy.

Insights from the complete chloroplast genome into the evolution of Sesamum indicum L.

PubMed

Zhang, Haiyang; Li, Chun; Miao, Hongmei; Xiong, Songjin

2013-01-01

Sesame (Sesamum indicum L.) is one of the oldest oilseed crops. In order to investigate the evolutionary characters according to the Sesame Genome Project, apart from sequencing its nuclear genome, we sequenced the complete chloroplast genome of S. indicum cv. Yuzhi 11 (white seeded) using Illumina and 454 sequencing. Comparisons of chloroplast genomes between S. indicum and the 18 other higher plants were then analyzed. The chloroplast genome of cv. Yuzhi 11 contains 153,338 bp and a total of 114 unique genes (KC569603). The number of chloroplast genes in sesame is the same as that in Nicotiana tabacum, Vitis vinifera and Platanus occidentalis. The variation in the length of the large single-copy (LSC) regions and inverted repeats (IR) in sesame compared to 18 other higher plant species was the main contributor to size variation in the cp genome in these species. The 77 functional chloroplast genes, except for ycf1 and ycf2, were highly conserved. The deletion of the cp ycf1 gene sequence in cp genomes may be due either to its transfer to the nuclear genome, as has occurred in sesame, or direct deletion, as has occurred in Panax ginseng and Cucumis sativus. The sesame ycf2 gene is only 5,721 bp in length and has lost about 1,179 bp. Nucleotides 1-585 of ycf2 when queried in BLAST had hits in the sesame draft genome. Five repeats (R10, R12, R13, R14 and R17) were unique to the sesame chloroplast genome. We also found that IR contraction/expansion in the cp genome alters its rate of evolution. Chloroplast genes and repeats display the signature of convergent evolution in sesame and other species. These findings provide a foundation for further investigation of cp genome evolution in Sesamum and other higher plants.

Genetic dissection and fine mapping of a novel dt gene associated with determinate growth habit in sesame.

PubMed

Zhang, Yanxin; Wang, Linhai; Gao, Yuan; Li, Donghua; Yu, Jingyin; Zhou, Rong; Zhang, Xiurong

2018-06-14

As an important oil crop, growth habit of sesame (Sesamum indicum L.) is naturally indeterminate, which brings about asynchronous maturity of capsules and causes loss of yield. The genetic basis of determinate growth habit in sesame was investigated by classical genetic analysis through multiple populations, results revealed that it was controlled by an unique recessive gene. The genotyping by sequencing (GBS) approach was employed for high-throughput SNP identification and genotyping in the F 2 population, then a high density bin map was constructed, the map was 1086.403 cM in length, which consisted of 1184 bins (13,679 SNPs), with an average of 0.918 cM between adjacent bins. Based on bin mapping in conjunction with SSR markers analysis in targeted region, the novel sesame determinacy gene was mapped on LG09 in a genome region of 41 kb. This study dissected genetic basis of determinate growth habit in sesame, constructed a new high-density bin map and mapped a novel determinacy gene. Results of this study demonstrate that we employed an optimized approach to get fine-accuracy, high-resolution and high-efficiency mapping result in sesame. The findings provided important foundation for sesame determinacy gene cloning and were expected to be applied in breeding for cultivars suited to mechanized production.

Effects of "Sesame Street": A Meta-Analysis of Children's Learning in 15 Countries

ERIC Educational Resources Information Center

Mares, Marie-Louise; Pan, Zhongdang

2013-01-01

"Sesame Street" is broadcast to millions of children globally, including in some of the world's poorest regions. This meta-analysis examines the effects of children's exposure to international co-productions of "Sesame Street", synthesizing the results of 24 studies, conducted with over 10,000 children in 15 countries. The results indicated…

AVE-Sesame 3: 25-MB sounding data

NASA Technical Reports Server (NTRS)

Williams, S. T.; Gerhard, M. L.; Gilchrist, L. P.; Turner, R. E.

1980-01-01

The rawinsonde sounding program for the AVE-SESAME 3 experiment is described and tabulated data at 25-mb intervals from the surface to 25 mb for the 23 National Weather Service and 19 special stations participating in the experiment are presented. Soundings were taken at 3 hr intervals beginning at 1200 GMT on April 25, 1979, and ending at 1200 GMT on April 26, 1979 (nine sounding times). The method of processing is discussed briefly, estimates of the rms errors in the data presented, an example of contact data given, reasons given for the termination of soundings below 100 mb, and soundings listed which exhibit abnormal characteristics.

Sesame and You, Two--A Teacher's Helper: A Revised Guide to Accompany a Videotape Package of Twenty Sesame Street Mini Shows.

ERIC Educational Resources Information Center

Sylves, David, Ed.; Sardina, Kathleen, Ed.

The teaching guide is intended to accompany a videotape package of 20 Sesame Street Mini Shows selected for their relevance to the education of young hearing impaired children. Individually described are segments of each Mini Show in terms of a description, captions, general objective, specific objectives, necessary preteaching, and related…

Genetic diversity assessment of sesame core collection in China by phenotype and molecular markers and extraction of a mini-core collection

PubMed Central

2012-01-01

Background Sesame (Sesamum indicum L.) is one of the four major oil crops in China. A sesame core collection (CC) was established in China in 2000, but no complete study on its genetic diversity has been carried out at either the phenotypic or molecular level. To provide technical guidance, a theoretical basis for further collection, effective protection, reasonable application, and a complete analysis of sesame genetic resources, a genetic diversity assessment of the sesame CC in China was conducted using phenotypic and molecular data and by extracting a sesame mini-core collection (MC). Results Results from a genetic diversity assessment of sesame CC in China were significantly inconsistent at the phenotypic and molecular levels. A Mantel test revealed the insignificant correlation between phenotype and molecular marker information (r = 0.0043, t = 0.1320, P = 0.5525). The Shannon-Weaver diversity index (I) and Nei genetic diversity index (h) were higher (I = 0.9537, h = 0.5490) when calculated using phenotypic data from the CC than when using molecular data (I = 0.3467, h = 0.2218). A mini-core collection (MC) containing 184 accessions was extracted based on both phenotypic and molecular data, with a low mean difference percentage (MD, 1.64%), low variance difference percentage (VD, 22.58%), large variable rate of coefficient of variance (VR, 114.86%), and large coincidence rate of range (CR, 95.76%). For molecular data, the diversity indices and the polymorphism information content (PIC) for the MC were significantly higher than for the CC. Compared to an alternative random sampling strategy, the advantages of capturing genetic diversity and validation by extracting a MC using an advanced maximization strategy were proven. Conclusions This study provides a comprehensive characterization of the phenotypic and molecular genetic diversities of the sesame CC in China. A MC was extracted using both phenotypic and molecular data. Low MD% and VD%, and large VR% and CR% suggested that the MC provides a good representation of the genetic diversity of the original CC. The MC was more genetically diverse with higher diversity indices and a higher PIC value than the CC. A MC may aid in reasonably and efficiently selecting materials for sesame breeding and for genotypic biological studies, and may also be used as a population for association mapping in sesame. PMID:23153260

Genetic diversity assessment of sesame core collection in China by phenotype and molecular markers and extraction of a mini-core collection.

PubMed

Zhang, Yanxin; Zhang, Xiurong; Che, Zhuo; Wang, Linhai; Wei, Wenliang; Li, Donghua

2012-11-15

Sesame (Sesamum indicum L.) is one of the four major oil crops in China. A sesame core collection (CC) was established in China in 2000, but no complete study on its genetic diversity has been carried out at either the phenotypic or molecular level. To provide technical guidance, a theoretical basis for further collection, effective protection, reasonable application, and a complete analysis of sesame genetic resources, a genetic diversity assessment of the sesame CC in China was conducted using phenotypic and molecular data and by extracting a sesame mini-core collection (MC). Results from a genetic diversity assessment of sesame CC in China were significantly inconsistent at the phenotypic and molecular levels. A Mantel test revealed the insignificant correlation between phenotype and molecular marker information (r = 0.0043, t = 0.1320, P = 0.5525). The Shannon-Weaver diversity index (I) and Nei genetic diversity index (h) were higher (I = 0.9537, h = 0.5490) when calculated using phenotypic data from the CC than when using molecular data (I = 0.3467, h = 0.2218). A mini-core collection (MC) containing 184 accessions was extracted based on both phenotypic and molecular data, with a low mean difference percentage (MD, 1.64%), low variance difference percentage (VD, 22.58%), large variable rate of coefficient of variance (VR, 114.86%), and large coincidence rate of range (CR, 95.76%). For molecular data, the diversity indices and the polymorphism information content (PIC) for the MC were significantly higher than for the CC. Compared to an alternative random sampling strategy, the advantages of capturing genetic diversity and validation by extracting a MC using an advanced maximization strategy were proven. This study provides a comprehensive characterization of the phenotypic and molecular genetic diversities of the sesame CC in China. A MC was extracted using both phenotypic and molecular data. Low MD% and VD%, and large VR% and CR% suggested that the MC provides a good representation of the genetic diversity of the original CC. The MC was more genetically diverse with higher diversity indices and a higher PIC value than the CC. A MC may aid in reasonably and efficiently selecting materials for sesame breeding and for genotypic biological studies, and may also be used as a population for association mapping in sesame.

7 CFR 1421.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... bundled peanut MALs and LDPs to a DMA. In the absence of a centralized MAL and LDP processing system for... seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, and other oilseeds as...

7 CFR 1421.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... bundled peanut MALs and LDPs to a DMA. In the absence of a centralized MAL and LDP processing system for... seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, and other oilseeds as...

7 CFR 1421.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... bundled peanut MALs and LDPs to a DMA. In the absence of a centralized MAL and LDP processing system for... seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, and other oilseeds as...

Effect of edible sesame oil on growth of clinical isolates of Candida albicans.

PubMed

Ogawa, Toshiko; Nishio, Junko; Okada, Shinobu

2014-07-01

Elderly individuals are at increased risk of oral thrush (oral candidiasis) due to decreased saliva secretion. Due to their antimicrobial properties, edible oils can be effective natural agents for oral care. The objective of the present study was to compare the effects of sesame oil, which is widely used for cooking in Asian countries, and two other edible oils on the growth of both mycelial and yeast forms of five clinical isolates of Candida albicans, a causative microorganism of oral thrush. We assessed the effect of each oil in concentrations of 0.078%, 0.156%, and 0.313% on growth of the mycelial forms of the clinical isolates over 24 hr using the crystal violet method. We also evaluated the effect of each oil on growth of the yeast forms by counting the number of viable yeast cells after culturing in the oils for 24 hr. Sesame oil inhibited the growth of both mycelial and yeast forms. Safflower and olive oil also inhibited the growth of both forms of C. albicans but to a lesser extent than sesame oil. The ability to inhibit the growth of the mycelial form correlated with sesame oil concentration. Roasting influenced growth inhibition ability and high-roasted sesame oil most effectively inhibited the yeast form. The growth inhibitory effect differed among the five isolates. We hypothesize that the sesamin and fatty acid components of sesame oil are involved in its antifungal activity. © The Author(s) 2013.

Effects of dietary sesame seeds on plasma tocopherol levels.

PubMed

Cooney, R V; Custer, L J; Okinaka, L; Franke, A A

2001-01-01

The tocopherols, the major vitamers of vitamin E, are believed to play a role in the prevention of human aging-related diseases such as cancer and heart disease, yet little is known concerning determinants of their plasma concentrations. Evidence from animal studies suggests that the dietary source of gamma-tocopherol can significantly affect plasma levels of this tocopherol as well as its functional vitamin E activity. To determine whether plasma levels of tocopherols in humans are similarly altered, a study was undertaken in which subjects (n = 9) were fed muffins containing equivalent amounts of gamma-tocopherol from sesame seeds, walnuts, or soy oil. We observed that consumption of as little as 5 mg of gamma-tocopherol per day over a three-day period from sesame seeds, but not from walnuts or soy oil, significantly elevated serum gamma-tocopherol levels (19.1% increase, p = 0.03) and depressed plasma beta-tocopherol (34% decrease, p = 0.01). No significant changes in baseline or postintervention plasma levels of cholesterol, triglycerides, or carotenoids were seen for any of the intervention groups. All subjects consuming sesame seed-containing muffins had detectable levels of the sesame lignan sesamolin in their plasma. Consumption of moderate amounts of sesame seeds appears to significantly increase plasma gamma-tocopherol and alter plasma tocopherol ratios in humans and is consistent with the effects of dietary sesame seeds observed in rats leading to elevated plasma gamma-tocopherol and enhanced vitamin E bioactivity.

Degradation mechanism of SESAMs under intense ultrashort pulses in modelocked VECSELs

NASA Astrophysics Data System (ADS)

Addamane, Sadhvikas; Shima, Darryl; Laurain, Alexandre; Chan, Hsiu-Ting; Balakrishnan, Ganesh; Moloney, Jerome V.

2018-02-01

Mode-locked VECSELs using SESAMs are a relatively less complex and cost-effective alternative to state-of-the-art ultrafast lasers based on solid-state or fiber lasers. VECSELs have seen considerable progress in device performance in terms of pulse width and peak power in the recent years. However, it appears that the combination of high power and short pulses can cause some irreversible damage to the SESAM. The degradation mechanism, which can lead to a reduction of the VECSEL output power over time, is not fully understood and deserves to be investigated and alleviated in order to achieve stable mode-locking over long periods of time. It is particularly important for VECSEL systems meant to be commercialized, needing long term operation with a long product lifetime. Here, we investigate the performance and robustness of a SESAM-modelocked VECSEL system under intense pulse intensity excitation. The effect of the degradation on the VECSEL performance is investigated using the SESAM in a VECSEL cavity supporting ultrashort pulses, while the degradation mechanism was investigated by exciting the SESAMs with an external femtosecond laser source. The decay of the photoluminescence (PL) and reflectivity under high excitation was monitored and the damaged samples were further analyzed using a thorough Transmission Electron Microscopy (TEM) analysis. It is found that the major contribution to the degradation is the field intensity and that the compositional damage is confined to the DBR region of the SESAM.

Evaluation of the basophil activation test and skin prick testing for the diagnosis of sesame food allergy.

PubMed

Appel, Michael Y; Nachshon, Liat; Elizur, Arnon; Levy, Michael B; Katz, Yitzhak; Goldberg, Michael R

2018-05-14

The prevalence of sesame food allergy (SFA) has increased over recent years, with the potential of anaphylactic reactions upon exposure. Oral food challenge (OFC) remains the diagnostic standard, yet its implementation may be risky. Commercial skin prick tests (SPT) have a low sensitivity. Investigation of alternate diagnostic methods is warranted. To evaluate the utility of SPT and the basophil activation test (BAT) for SFA diagnosis. Eighty-two patients with suspected SFA completed an open OFC to sesame or reported a recent confirmed reaction. Patients were administered skin prick tests (SPT) with commercial sesame seed extract (CSSE), and a high protein concentration sesame extract (HPSE) (100 mg/ml protein). Whole blood from eighty patients was stimulated with sesame seed extract (40-10000 ng/ml protein) for BAT), assessing CD63 and CD203c as activation markers. Sixty patients (73%) had IgE-mediated reactions to sesame, and 22 (27%) did not react. Receiver operating characteristic (ROC) curve analysis demonstrated an area under the curve (AUC) of 0.87 for HPSE-SPT, and 0.66 for CSSE-SPT. At 1000 ng/ml of sesame protein, induction of CD63 and CD203c was weakly but significantly associated with OFC eliciting dose by rank (Spearman's rho= -0.42 (P<0.01) and -0.35 (P<0.05) for CD63 and CD203c, respectively). By ROC analysis, the AUC for CD63 was 0.86, and was 0.81 for CD203c sesame-induced basophil expression. Using HPSE-SPT as a first test to definitively diagnose (n=24) or rule out (n=5) SFA and BAT as a second test to diagnose the remainder, results in the correct classification of 73/80 (91%) patients, leaving one false negative and four false positive patients. Two BAT non-responders remain unclassified by this algorithm. While prospective cohort validation is necessary, joint utilization of BAT and SPT with HPSE extract may obviate the need for OFC in most SFA patients. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Updated sesame genome assembly and fine mapping of plant height and seed coat color QTLs using a new high-density genetic map.

PubMed

Wang, Linhai; Xia, Qiuju; Zhang, Yanxin; Zhu, Xiaodong; Zhu, Xiaofeng; Li, Donghua; Ni, Xuemei; Gao, Yuan; Xiang, Haitao; Wei, Xin; Yu, Jingyin; Quan, Zhiwu; Zhang, Xiurong

2016-01-05

Sesame is an important high-quality oil seed crop. The sesame genome was de novo sequenced and assembled in 2014 (version 1.0); however, the number of anchored pseudomolecules was higher than the chromosome number (2n = 2x = 26) due to the lack of a high-density genetic map with 13 linkage groups. We resequenced a permanent population consisting of 430 recombinant inbred lines and constructed a genetic map to improve the sesame genome assembly. We successfully anchored 327 scaffolds onto 13 pseudomolecules. The new genome assembly (version 2.0) included 97.5 % of the scaffolds greater than 150 kb in size present in assembly version 1.0 and increased the total pseudomolecule length from 233.7 to 258.4 Mb with 94.3 % of the genome assembled and 97.2 % of the predicted gene models anchored. Based on the new genome assembly, a bin map including 1,522 bins spanning 1090.99 cM was generated and used to identified 41 quantitative trait loci (QTLs) for sesame plant height and 9 for seed coat color. The plant height-related QTLs explained 3-24 % the phenotypic variation (mean value, 8 %), and 29 of them were detected in at least two field trials. Two major loci (qPH-8.2 and qPH-3.3) that contributed 23 and 18 % of the plant height were located in 350 and 928-kb spaces on Chr8 and Chr3, respectively. qPH-3.3, is predicted to be responsible for the semi-dwarf sesame plant phenotype and contains 102 candidate genes. This is the first report of a sesame semi-dwarf locus and provides an interesting opportunity for a plant architecture study of the sesame. For the sesame seed coat color, the QTLs of the color spaces L*, a*, and b* were detected with contribution rates of 3-46 %. qSCb-4.1 contributed approximately 39 % of the b* value and was located on Chr4 in a 199.9-kb space. A list of 32 candidate genes for the locus, including a predicted black seed coat-related gene, was determined by screening the newly anchored genome. This study offers a high-density genetic map and an improved assembly of the sesame genome. The number of linkage groups and pseudomolecules in this assembly equals the number of sesame chromosomes for the first time. The map and updated genome assembly are expected to serve as a platform for future comparative genomics and genetic studies.

SESAME and beyond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mtingwa, Sekazi K.; Winick, Herman

Last week, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, the Palestinian Authority, and Turkey, as well as other nations and international organizations, gathered in Jordan to inaugurate the Synchrotron-light for Experimental Science and Applications in the Middle East (SESAME) project. Having persevered through two decades of political and financial challenges, this complex machine is poised to run its first experiments this year. Indeed, SESAME represents the power of science in bringing together countries—even those with frayed relations—under a common goal of advancing knowledge for the benefit of all humankind. The triumph of SESAME, and the outpouring of research results from othermore » light sources around the world, have spurred interest in building synchrotrons in developing countries.« less

SESAME and beyond

DOE PAGES

Mtingwa, Sekazi K.; Winick, Herman

2017-05-26

Last week, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, the Palestinian Authority, and Turkey, as well as other nations and international organizations, gathered in Jordan to inaugurate the Synchrotron-light for Experimental Science and Applications in the Middle East (SESAME) project. Having persevered through two decades of political and financial challenges, this complex machine is poised to run its first experiments this year. Indeed, SESAME represents the power of science in bringing together countries—even those with frayed relations—under a common goal of advancing knowledge for the benefit of all humankind. The triumph of SESAME, and the outpouring of research results from othermore » light sources around the world, have spurred interest in building synchrotrons in developing countries.« less

Natural occurrence of aflatoxins in Chinese peanut butter and sesame paste.

PubMed

Li, Feng-Qin; Li, Yu-Wei; Wang, Ye-Ru; Luo, Xue-Yun

2009-05-13

A study on the natural occurrence of aflatoxins in Chinese peanut butter and sesame paste samples was conducted. Aflatoxin B(1) (AFB(1)) was the predominant toxin detected abundantly and frequently at a level up to 68.51 microg/kg in 41 of 50 peanut butter samples and 20.45 microg/kg in 37 of 100 sesame paste samples analyzed by liquid chromatography (LC). Of the AFB(1)-positive samples, 15 (37%) and 1 (2%) peanut butter samples with AFB(1) exceed European Union (EU) and Chinese regulations, respectively, whereas 19 and 32% of sesame paste samples contained AFB(1) higher than Chinese and EU regulations, respectively. Fourteen and 1 peanut butter samples and 10 and 7 sesame paste samples, respectively, will be legally claimed as positive, rejected, and even banned with consideration of an uncertainty of 40% for AFB(1), based on EU and Chinese regulations. Seeking to balance health benefits with the potential trade disruptions that regulations can cause is the issue of concern.

Control of Origin of Sesame Oil from Various Countries by Stable Isotope Analysis and DNA Based Markers—A Pilot Study

PubMed Central

Horacek, Micha; Hansel-Hohl, Karin; Burg, Kornel; Soja, Gerhard; Okello-Anyanga, Walter; Fluch, Silvia

2015-01-01

The indication of origin of sesame seeds and sesame oil is one of the important factors influencing its price, as it is produced in many regions worldwide and certain provenances are especially sought after. We joined stable carbon and hydrogen isotope analysis with DNA based molecular marker analysis to study their combined potential for the discrimination of different origins of sesame seeds. For the stable carbon and hydrogen isotope data a positive correlation between both isotope parameters was observed, indicating a dominant combined influence of climate and water availability. This enabled discrimination between sesame samples from tropical and subtropical/moderate climatic provenances. Carbon isotope values also showed differences between oil from black and white sesame seeds from identical locations, indicating higher water use efficiency of plants producing black seeds. DNA based markers gave independent evidence for geographic variation as well as provided information on the genetic relatedness of the investigated samples. Depending on the differences in ambient environmental conditions and in the genotypic fingerprint, a combination of both analytical methods is a very powerful tool to assess the declared geographic origin. To our knowledge this is the first paper on food authenticity combining the stable isotope analysis of bio-elements with DNA based markers and their combined statistical analysis. PMID:25831054

Control of origin of sesame oil from various countries by stable isotope analysis and DNA based markers--a pilot study.

PubMed

Horacek, Micha; Hansel-Hohl, Karin; Burg, Kornel; Soja, Gerhard; Okello-Anyanga, Walter; Fluch, Silvia

2015-01-01

The indication of origin of sesame seeds and sesame oil is one of the important factors influencing its price, as it is produced in many regions worldwide and certain provenances are especially sought after. We joined stable carbon and hydrogen isotope analysis with DNA based molecular marker analysis to study their combined potential for the discrimination of different origins of sesame seeds. For the stable carbon and hydrogen isotope data a positive correlation between both isotope parameters was observed, indicating a dominant combined influence of climate and water availability. This enabled discrimination between sesame samples from tropical and subtropical/moderate climatic provenances. Carbon isotope values also showed differences between oil from black and white sesame seeds from identical locations, indicating higher water use efficiency of plants producing black seeds. DNA based markers gave independent evidence for geographic variation as well as provided information on the genetic relatedness of the investigated samples. Depending on the differences in ambient environmental conditions and in the genotypic fingerprint, a combination of both analytical methods is a very powerful tool to assess the declared geographic origin. To our knowledge this is the first paper on food authenticity combining the stable isotope analysis of bio-elements with DNA based markers and their combined statistical analysis.

Improving halva quality with dietary fibres of sesame seed coats and date pulp, enriched with emulsifier.

PubMed

Elleuch, Mohamed; Bedigian, Dorothea; Maazoun, Bouthaina; Besbes, Souhail; Blecker, Christophe; Attia, Hamadi

2014-02-15

Supplementation of halva with waste products of manufacturing, for example defatted sesame seed coats (testae) and date fibre concentrate, can improve its nutritional and organoleptic qualities. These constituents provide high fibre content and technological potential for retaining water and fat. Standard halva supplemented with date fibre concentrate, defatted sesame testae and emulsifier was evaluated for oil separation, texture and colour changes, sensory qualities and acceptability to a taste panel. Addition of both fibres with an emulsifier, improved emulsion stability and increased the hardness of halva significantly. The functional properties of sesame testae and date fibres promote nutrition and health, supplying polyphenol antioxidants and laxative benefits. Copyright © 2013 Elsevier Ltd. All rights reserved.

Effect of infrared heating on the formation of sesamol and quality of defatted flours from Sesamum indicum L.

PubMed

Kumar, C Mahendra; Appu Rao, A G; Singh, Sridevi Annapurna

2009-01-01

Infrared (IR) heating offers several advantages over conventional heating in terms of heat transfer efficiency, compactness of equipment, and quality of the products. Roasting of sesame seeds degrades the lignan sesamolin to sesamol, which increases the oxidative stability of sesame oil synergistically with tocopherols. IR (near infrared, 1.1 to 1.3 microm, 6 kW power) roasting conditions were optimized for the conversion of sesamolin to sesamol. The resultant oil was evaluated for sesamol and tocopherol content as well as oxidative stability. The defatted flours were evaluated for their nutritional content and functionality. IR roasting of sesame seeds at 200 degrees C for 30 min increased the efficiency of conversion of sesamolin to sesamol (51% to 82%) compared to conventional heating. The gamma-tocopherol content decreased by 17% and 25% in oils treated at 200 and 220 degrees C for 30 min, respectively. There were no significant differences in the tocopherol content and oxidative stability of the oil. Methionine and cysteine content of the flours remained unchanged due to roasting. The functional properties of defatted flours obtained from either IR roasted or conventionally roasted sesame seeds remained the same. Practical Applications: Sesame oil is stable to oxidation compared to other vegetable oils. This stability can be attributed to the presence of tocopherols and the formation of sesamol, the thermal degradation product of sesamolin-a lignan present in sesame. Roasting of sesame seeds before oil extraction increases sesamol content which is a more potent antioxidant than the parent molecule. The conversion efficiency of sesamolin to sesamol is increased by 31% by infrared roasting of seeds compared to electric drum roasting. This can be used industrially to obtain roasted oil with greater oxidative stability.

Microscopic analysis of saturable absorbers: Semiconductor saturable absorber mirrors versus graphene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hader, J.; Moloney, J. V.; College of Optical Sciences, University of Arizona, Tucson, Arizona 85721

2016-02-07

Fully microscopic many-body calculations are used to study the influence of strong sub-picosecond pulses on the carrier distributions and corresponding optical response in saturable absorbers used for mode-locking—semiconductor (quantum well) saturable absorber mirrors (SESAMs) and single layer graphene based saturable absorber mirrors (GSAMs). Unlike in GSAMs, the saturation fluence and recovery time in SESAMs show a strong spectral dependence. While the saturation fluence in the SESAM is minimal at the excitonic bandgap, the optimal recovery time and least pulse distortion due to group delay dispersion are found for excitation higher in the first subband. For excitation near the SESAM bandgap,more » the saturation fluence is about one tenth of that in the GSAM. At energies above the bandgap, the fluences in both systems become similar. A strong dependence of the saturation fluence on the pulse width in both systems is caused by carrier relaxation during the pulse. The recovery time in graphene is found to be about two to four times faster than that in the SESAMs. The occurrence of negative differential transmission in graphene is shown to be caused by dopant related carriers. In SESAMs, a negative differential transmission is found when exciting below the excitonic resonance where excitation induced dephasing leads to an enhancement of the absorption. Comparisons of the simulation data to the experiment show a very good quantitative agreement.« less

Sesame Street Around the World: The Educational Impact

ERIC Educational Resources Information Center

Cook, Thomas D.; Conner, Ross F.

1976-01-01

Evaluates seven studies concerned with the influence of Sesame Street on the development of learning skills in preschool children and provides a balance sheet of achievements, limitations and unanswered questions. (MH)

Prevalence, level and distribution of Salmonella in shipments of imported capsicum and sesame seed spice offered for entry to the United States: observations and modeling results.

PubMed

Van Doren, Jane M; Blodgett, Robert J; Pouillot, Régis; Westerman, Ann; Kleinmeier, Daria; Ziobro, George C; Ma, Yinqing; Hammack, Thomas S; Gill, Vikas; Muckenfuss, Martin F; Fabbri, Linda

2013-12-01

In response to increased concerns about spice safety, the United States Food and Drug Administration (FDA) initiated research to characterize the prevalence and levels of Salmonella in imported spices. 299 imported dried capsicum shipments and 233 imported sesame seed shipments offered for entry to the United States were sampled. Observed Salmonella shipment prevalence was 3.3% (1500 g examined; 95% CI 1.6-6.1%) for capsicum and 9.9% (1500 g; 95% Confidence Interval (CI) 6.3-14%) for sesame seed. Within shipment contamination was not inconsistent with a Poisson distribution. Shipment mean Salmonella level estimates among contaminated shipments ranged from 6 × 10(-4) to 0.09 (capsicum) or 6 × 10(-4) to 0.04 (sesame seed) MPN/g. A gamma-Poisson model provided the best fit to observed data for both imported shipments of capsicum and imported shipments of sesame seed sampled in this study among the six parametric models considered. Shipment mean levels of Salmonella vary widely between shipments; many contaminated shipments contain low levels of contamination. Examination of sampling plan efficacy for identifying contaminated spice shipments from these distributions indicates that sample size of spice examined is critical. Sampling protocols examining 25 g samples are predicted to be able to identify a small fraction of contaminated shipments of imported capsicum or sesame seeds. Published by Elsevier Ltd.

Effect of sesame on sperm quality of infertile men.

PubMed

Khani, Behnaz; Bidgoli, Soroor Rabbani; Moattar, Fariborz; Hassani, Hassan

2013-03-01

High level of semen reactive oxygen species is considered as an important factor in male infertility. Sesame has antioxidant properties, which could be effective on improvement of semen parameters. This study was designed to determine the effects of sesame on sperm quality. Twenty-five infertile men entered this clinical trial. They were treated with a 3-months course of taking 0.5 mg/kg sesame. The pre intervention sperm analysis (sperm count, motile sperm percentage and normal morphology sperm percentage) was compared with post treatment sperm analysis. Based on the post intervention seamen analysis, patients were advised to undergo either IVF or ICSI to assess their fertility status. There was significant improvement in the sperm count (10.56 ± 5.25 vs. 22.71 ± 30.14 million per ml) and motility (15.32 ± 13.58 vs. 23.32 ± 20.61 percent) after treatment with sesame (P value: 0.04 and <0.0001 respectively), but there was no significant improvement in sperm morphology after the treatment (10.72 ± 6.66 vs. 13.20 ± 11.14 percent, P value: 0.10). Three patients (12%) underwent IUI, which resulted in 1 successful pregnancy. Two patients (8%) underwent ICSI, which was not successful; however 2 (8%) patients had spontaneous pregnancy. Fortunately, all pregnancies led to live birth. Except 1 case of diarrhea, no other major side effect was reported. Sesame improved sperm count and motility, and can be prescribed as an effective and safe method for male factor infertility.

Carrier-envelope offset stabilization of a GHz repetition rate femtosecond laser using opto-optical modulation of a SESAM.

PubMed

Hakobyan, Sargis; Wittwer, Valentin J; Gürel, Kutan; Mayer, Aline S; Schilt, Stéphane; Südmeyer, Thomas

2017-11-15

We demonstrate, to the best of our knowledge, the first carrier-envelope offset (CEO) frequency stabilization of a GHz femtosecond laser based on opto-optical modulation (OOM) of a semiconductor saturable absorber mirror (SESAM). The 1.05-GHz laser is based on a Yb:CALGO gain crystal and emits sub-100-fs pulses with 2.1-W average power at a center wavelength of 1055 nm. The SESAM plays two key roles: it starts and stabilizes the mode-locking operation and is simultaneously used as an actuator to control the CEO frequency. This second functionality is implemented by pumping the SESAM with a continuous-wave 980-nm laser diode in order to slightly modify its nonlinear reflectivity. We use the standard f-to-2f method for detection of the CEO frequency, which is stabilized by applying a feedback signal to the current of the SESAM pump diode. We compare the SESAM-OOM stabilization with the traditional method of gain modulation via control of the pump power of the Yb:CALGO gain crystal. While the bandwidth for gain modulation is intrinsically limited to ∼250  kHz by the laser cavity dynamics, we show that the OOM provides a feedback bandwidth above 500 kHz. Hence, we were able to obtain a residual integrated phase noise of 430 mrad for the stabilized CEO beat, which represents an improvement of more than 30% compared to gain modulation stabilization.

Situational awareness for unmanned ground vehicles in semi-structured environments

NASA Astrophysics Data System (ADS)

Goodsell, Thomas G.; Snorrason, Magnus; Stevens, Mark R.

2002-07-01

Situational Awareness (SA) is a critical component of effective autonomous vehicles, reducing operator workload and allowing an operator to command multiple vehicles or simultaneously perform other tasks. Our Scene Estimation & Situational Awareness Mapping Engine (SESAME) provides SA for mobile robots in semi-structured scenes, such as parking lots and city streets. SESAME autonomously builds volumetric models for scene analysis. For example, a SES-AME equipped robot can build a low-resolution 3-D model of a row of cars, then approach a specific car and build a high-resolution model from a few stereo snapshots. The model can be used onboard to determine the type of car and locate its license plate, or the model can be segmented out and sent back to an operator who can view it from different viewpoints. As new views of the scene are obtained, the model is updated and changes are tracked (such as cars arriving or departing). Since the robot's position must be accurately known, SESAME also has automated techniques for deter-mining the position and orientation of the camera (and hence, robot) with respect to existing maps. This paper presents an overview of the SESAME architecture and algorithms, including our model generation algorithm.

7 CFR 1436.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., dryers, processing plants, or cold storage facilities used for the storage and handling of any..., oats, wheat, barley, rice, raw or refined sugar, soybeans, sunflower seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, other oilseeds as determined and announced by CCC, dry peas...

7 CFR 1436.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., dryers, processing plants, or cold storage facilities used for the storage and handling of any..., oats, wheat, barley, rice, raw or refined sugar, soybeans, sunflower seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, other oilseeds as determined and announced by CCC, dry peas...

7 CFR 1436.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., dryers, processing plants, or cold storage facilities used for the storage and handling of any..., oats, wheat, barley, rice, raw or refined sugar, soybeans, sunflower seed, canola, rapeseed, safflower, flaxseed, mustard seed, crambe, sesame seed, other oilseeds as determined and announced by CCC, dry peas...

SESAME seeks cash to open its doors

NASA Astrophysics Data System (ADS)

Banks, Michael

2008-12-01

Researchers from the Middle East met in Jordan last month to celebrate progress towards the region's first synchrotron-radiation source, which is due to be ready for users by 2011. Known as SESAME, the facility is being built near the Al-Baqa' Applied University in Allan, about 30 km from the Jordanian capital Amman, and is designed to promote peaceful scientific co-operation between nations in the troubled region. However, the project still has to find 15m - a fifth of the total costs - in order to finish construction or SESAME risks being delayed beyond 2011.

Pharmaco-physio-psychologic effect of Ayurvedic oil-dripping treatment using an essential oil from Lavendula angustifolia.

PubMed

Xu, Fenghao; Uebaba, Kazuo; Ogawa, Hiroko; Tatsuse, Takeshi; Wang, Bing-Hong; Hisajima, Tatsuya; Venkatraman, Sonia

2008-10-01

Ayurvedic oil-dripping treatment, Shirodhara, involves the use of medicated herbal sesame oils. In our previous reports, we found that Shirodhara with plain sesame oil induced anxiolysis and an altered state of consciousness (ASC) in healthy subjects. We studied the pharmaco-physio-psychologic effect of Shirodhara with medicated sesame oil including an essential oil from Lavendula angustifolia (lavender) in the present study. Sixteen (16) healthy females (38 +/- 8 years old) were assigned at random to three treatments applied by a robotic oil-dripping system: plain sesame oil (plain Shirodhara), medicated sesame oil with a 0.3 volume % of lavender essential oil (lavender Shirodhara), or the control supine position. Psychophysiologic parameters including the heart rate, skin temperature of the dorsum of hands and feet, as well as anxiety and ASC were monitored, and the rates of change of these items were calculated to assess the psychophysiologic changes brought about by Shirodhara. Lavender Shirodhara showed potent anxiolytic and ASC-inducing or promoting effects, and induced the largest increase in foot skin temperature. The correlation between anxiolysis and ASC, as well as the correlation between these psychologic effects and the elevated foot skin temperature were larger in the lavender Shirodhara than in the other two conditions. It was speculated that the psycho-physiologic effects of lavender Shirodhara would be brought about by three mechanisms: (1) the well-known relaxing action of essential oils from L. angustifolia mediated by olfactory nerves, (2) the pharmacologic action of substances absorbed through the skin or mucosa in the sesame oil or lavender essential oil, and (3) the physiologic effect of sesame oil dripped on the forehead induced by the somato-autonomic reflex through thermosensors or pressure sensors in the skin or hair follicles via the trigeminal cranial nerve. The complicated pharmaco-physio-psychologic action of Ayurvedic oil treatment may provide a useful model for future pharmaco-physio-psychotherapy.

Open sesame: Identification of sesame oil and oil soot ink in organic deposits of Tang Dynasty lamps from Astana necropolis in China

PubMed Central

Knaust, Andrea; Verbavatz, Jean-Marc; Mai, Huijuan; Wang, Bo; Wang, Changsui; Shevchenko, Andrej

2017-01-01

Lamp illuminants evidence the exploitation of natural resources, animal and plant domestication, commerce, religious practices and nutrition of ancient populations. However, the physicochemical analysis of their major constituent—burned, degraded and aged mixture of triacylglycerols is imprecise and may lead to ambiguous interpretations. We applied proteomics to analyze fuel deposits from eight lamps dated by 6th to 8th centuries AD that were excavated at the Astana necropolis (Xinjiang, China) and determined their origin by identifying organism-specific proteins. Proteomics evidence corroborated and detailed the assignments of source organism relying upon comparative profiling of intact triacylglycerols by shotgun lipidomics. We found that ruminant (mostly, sheep) fat, cattle ghee and sesame oil were common combustibles in Astana and concluded that sesame as an oilseed appeared in China under Tang Dynasty concomitantly with the expansion of Buddhism. PMID:28234998

IAA-producing Penicillium sp. NICS01 triggers plant growth and suppresses Fusarium sp.-induced oxidative stress in sesame (Sesamum indicum L.).

PubMed

Radhakrishnan, Ramalingam; Shim, Kang-Bo; Lee, Byeong-Won; Hwang, Chung-Dong; Pae, Suk-Bok; Park, Chang-Hwan; Kim, Sung-Up; Lee, Choon-Ki; Baek, In-Youl

2013-06-28

Application of rhizospheric fungi is an effective and environmentally friendly method of improving plant growth and controlling many plant diseases. The current study was aimed to identify phytohormone-producing fungi from soil, to understand their roles in sesame plant growth, and to control Fusarium disease. Three predominant fungi (PNF1, PNF2, and PNF3) isolated from the rhizospheric soil of peanut plants were screened for their growth-promoting efficiency on sesame seedlings. Among these isolates, PNF2 significantly increased the shoot length and fresh weight of seedlings compared with controls. Analysis of the fungal culture filtrate showed a higher concentration of indole acetic acid in PNF2 than in the other isolates. PNF2 was identified as Penicillium sp. on the basis of phylogenetic analysis of ITS sequence similarity. The in vitro biocontrol activity of Penicillium sp. against Fusarium sp. was exhibited by a 49% inhibition of mycelial growth in a dual culture bioassay and by hyphal injuries as observed by scanning electron microscopy. In addition, greenhouse experiments revealed that Fusarium inhibited growth in sesame plants by damaging lipid membranes and reducing protein content. Co-cultivation with Penicillium sp. mitigated Fusarium-induced oxidative stress in sesame plants by limiting membrane lipid peroxidation, and by increasing the protein concentration, levels of antioxidants such as total polyphenols, and peroxidase and polyphenoloxidase activities. Thus, our findings suggest that Penicillium sp. is a potent plant growthpromoting fungus that has the ability to ameliorate damage caused by Fusarium infection in sesame cultivation.

Mineral and Anti-Nutritional Contents of Niger Seed (Guizotia abyssinica (L.f.) Cass., Linseed (Linumusitatissimum L.) and Sesame (Sesamumindicum L.) Varieties Grown in Ethiopia.

PubMed

Deme, Tesfaye; Haki, Gulelat D; Retta, Nigussie; Woldegiorgis, Ashagrie; Geleta, Mulatu

2017-04-01

Oilseeds are rich sources of micronutrients and contribute to combating malnutrition caused by micronutrient deficiency. The objective of this study was to investigate the mineral and anti-nutritional contents of different varieties of niger seed, linseed and sesame. Five niger seed, eight linseed and ten sesame varieties were used. Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES) was used for mineral analysis and the standard method was adopted to estimate tannin and phytate. Twelve mineral elements; Ca, K, Mg, Na, P, B, Cu, Fe, Mn, S, Se and Zn were analyzed for each oilseed variety. In niger seed, phosphorous was the most abundant mineral element ranging from 661 to 867 mg/100 g and selenium was the least, ranging from 0.1 to 0.33 mg/100 g. Potassium was recorded in the range of 502 to 732 mg/100 g for linseed varieties. Calcium was the most common mineral element in sesame (1112 to 1787 mg/100 g). The average phytate contents of niger seed, linseed and sesame varieties were353 mg/100 g, 104 mg/100 g and 285 mg/100 g, respectively. Tannin ranged from 91 to 201 mg/100 g, 96 to 695 mg/100 g and 85 to 660 mg/100 g in niger seed, linseed and sesame, respectively. In conclusion, there is a significant variation among the varieties within each crop species as well as among the different oilseeds in terms of their mineral and anti-nutritional contents.

Words from "Sesame Street": Learning Vocabulary While Viewing.

ERIC Educational Resources Information Center

Rice, Mabel L.; And Others

1990-01-01

Suggests that the content and presentation formats of "Sesame Street" are well suited to preschoolers' vocabulary development, independently of parent education, family size, child gender, and parental attitudes. Findings also suggest the feasibility of tutorial uses of the video medium. (RH)

Mode-locked Tm,Ho:KLu(WO(4))(2) laser at 2060 nm using InGaSb-based SESAMs.

PubMed

Aleksandrov, Veselin; Gluth, Alexander; Petrov, Valentin; Buchvarov, Ivan; Steinmeyer, Günter; Paajaste, Jonna; Suomalainen, Soile; Härkönen, Antti; Guina, Mircea; Mateos, Xavier; Díaz, Francesc; Griebner, Uwe

2015-02-23

Passive mode-locking of a Tm,Ho:KLu(WO(4))(2) laser operating at 2060 nm using different designs of InGaAsSb quantum-well based semiconductor saturable absorber mirrors (SESAMs) is demonstrated. The self-starting mode-locked laser delivers pulse durations between 4 and 8 ps at a repetition rate of 93 MHz with maximum average output power of 155 mW. Mode-locking performance of a Tm,Ho:KLu(WO(4))(2) laser is compared for usage of a SESAM to a single-walled carbon nanotube saturable absorber.

Development of dielectric barrier discharge for reducing microbial contamination in pepper (Piper nigrum) and sesame (Sesamum indicum Linn.) powder

NASA Astrophysics Data System (ADS)

Promping, J.; Prakongsil, P.; Picha, R.; Traikool, T.

2017-09-01

This research is designed to determine the efficacy of DBD plasma to reduce the microbial contamination of pepper and sesame powder. The AC high voltage power supply was used with voltages of up to 20 kV and the frequency of 5.5 kHz was applied to the DBD. The gap of DBD electrodes was set at 5 mm. In raw initial samples, the total aerobic count of pepper (Piper nigrum) was found at quite a high level at 5.40 × 105 CFU/g. Coliform bacteria was also found in both the sesame (Sesamum indicum Linn.) powder and pepper (Piper nigrum) powder. Both kinds of samples were treated with plasma for 2, 4, 6 and 10 minutes. Results indicated that plasma treatment at 2-10 minutes reduced the total aerobic count of pepper allowed to achieve the acceptable microbial level for spices. The plasma treatment times in this experiment were also effective in reducing faecal coliform bacteria in both pepper and sesame powders (MPN/g <3) as indicated in the standard. Plasma from dielectric barrier charge can reduce Staphylococcus epidermidis in sesame powder which was artificially contaminated with 3.50 × 102 CFU/g resulting in 0.15-0.5 log cycle reductions of microbial load.

Real-time near-infrared spectroscopic inspection system for adulterated sesame oil

NASA Astrophysics Data System (ADS)

Kang, Sukwon; Lee, Kang-jin; Son, Jaeryong; Kim, Moon S.

2010-04-01

Sesame seed oil is popular and expensive in Korea and has been often mixed with other less expensive vegetable oils. The objective of this research is to develop an economical and rapid adulteration determination system for sesame seed oil mixed with other vegetable oils. A recently developed inspection system consists of a light source, a measuring unit, a spectrophotometer, fiber optics, and a data acquisition module. A near-infrared transmittance spectroscopic method was used to develop the prediction model using Partial Least Square (PLS). Sesame seed oil mixed with a range of concentrations of corn, or perilla, or soybean oil was measured in 8 mm diameter glass tubes. For the model development, a correlation coefficient value of 0.98 was observed for corn, perilla, and soybean oil mixtures with standard errors of correlation of 6.32%, 6.16%, and 5.67%, respectively. From the prediction model, the correlation coefficients of corn oil, perilla oil, and soybean oil were 0.98, 0.97 and 0.98, respectively. The Standard Error of Prediction (SEP) for corn oil, perilla oil, and soybean oil were 6.52%, 6.89% and 5.88%, respectively. The results indicated that this system can potentially be used as a rapid non-destructive adulteration analysis tool for sesame seed oil mixed with other vegetable oils.

Some microbial, chemical and sensorial properties of gamma irradiated sesame (Sesamum indicum L.) seeds.

PubMed

Al-Bachir, Mahfouz

2016-04-15

The effect on microbial, chemical and sensorial properties of sesame seeds was determined after irradiation and storage. The sesame seeds were analyzed before and after irradiation with 3, 6 and 9 kGy of gamma irradiation, and after 6 and 12 months of storage. The results showed that gamma irradiation had no significant (p>0.05) effect on the moisture, ash and fat content on sesame seeds. While, small differences, but sometimes significant (p<0.05), on protein and sugar contents were recorded between irradiated and non-irradiated samples. Total acidity percentage decreased significantly (p<0.05), while total volatile basic nitrogen (TVBN) increased significantly (p<0.05) due to irradiation. During storage, total acidity increased (p<0.05) and TVBN decreased (p<0.05). Gamma irradiation reduced the microorganisms of sesame seeds. Samples treated with 3 kGy or more remained completely free of fungi throughout the storage. While, only the samples treated with 9 kGy remained completely free of bacteria at the end of storage period (after 12 months). The scores for taste, flavor, color and texture of irradiated samples were higher, but not significantly (p>0.05) than those of non-irradiated samples. Copyright © 2015 Elsevier Ltd. All rights reserved.

Genetic diversity and vector transmission of phytoplasmas associated with sesame phyllody in Iran.

PubMed

Salehi, M; Esmailzadeh Hosseini, S A; Salehi, E; Bertaccini, A

2017-03-01

During 2010-14 surveys in the major sesame growing areas of Fars, Yazd and Isfahan provinces (Iran), genetic diversity and vector transmission of phytoplasmas associated with sesame phyllody were studied. Virtual RFLP, phylogenetic, and DNA homology analyses of partial 16S ribosomal sequences of phytoplasma strains associated with symptomatic plants revealed the presence of phytoplasmas referable to three ribosomal subgroups, 16SrII-D, 16SrVI-A, and 16SrIX-C. The same analyses using 16S rDNA sequences from sesame phyllody-associated phytoplasmas retrieved from GenBank database showed the presence of phytoplasmas clustering with strains in the same subgroups in other Iranian provinces including Bushehr and Khorasan Razavi. Circulifer haematoceps and Orosius albicinctus, known vectors of the disease in Iran, were tested for transmission of the strains identified in this study. C. haematoceps transmitted 16SrII-D, 16SrVI-A, and 16SrIX-C phytoplasmas, while O. albicinctus only transmitted 16SrII-D strains. Based on the results of the present study and considering the reported presence of phytoplasmas belonging to the same ribosomal subgroups in other crops, sesame fields probably play an important role in the epidemiology of other diseases associated with these phytoplasmas in Iran.

Immunoaffinity column cleanup with liquid chromatography using postcolumn bromination for the determination of aflatoxins in black and white sesame seed: single-laboratory validation.

PubMed

Liu, Guihua; Zhu, Zhou; Cheng, Jinquan; Senyuva, Hamide Z

2012-01-01

A single-laboratory validation was conducted to establish the effectiveness of an immunoaffinity column cleanup procedure followed by LC with fluorescence detection for the determination of aflatoxins B1, B2, G1, and G2 in sesame seeds. The sample is homogenized with 50% water (w/w) to form a slurry, then the test portion is extracted with methanol-water (60 + 40, v/v) using a high-speed blender. The sample extract is filtered, diluted with 15% Tween 20 in phosphate-buffered saline solution, and applied to an immunoaffinity column. Aflatoxins are removed with neat methanol, then directly determined by RP-LC with fluorescence detection using postcolumn bromination (Kobra cell). Test portions of blank white sesame seed slurry were spiked with a mixture of aflatoxins to give total levels of 4 and 10 microg/kg. Recoveries for individual and total aflatoxins ranged from 92.7 to 110.3% for spiked samples. Based on results for spiked sesame paste (triplicates at two levels), the RSD for repeatability (RSD(r)) averaged 1.1% for total aflatoxins and 1.4% for aflatoxin B1. The method was demonstrated to be applicable to naturally contaminated samples of black and white sesame seeds obtained from local markets in China.

Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds

PubMed Central

Abbasi, Arshad Mehmood; Zheng, Bisheng

2016-01-01

Sesame (Sesamum indicum L.) seeds are popular nutritional food but with limited knowledge about their antioxidant and antiproliferative activities of various varieties. Phytochemical profiles and antioxidant and antiproliferative activities of six varieties of sesame (Sesamum indicum L.) seeds were studied. Fenheizhi3 (black) cultivar exhibited the maximum contents of total phenolics and lignans and values of total oxygen radical absorbance capacity (ORAC) and antiproliferative activity (EC50) against HepG2 cells. Bound ORAC values showed strong associations with bound phenolics contents (r = 0.976, p < 0.01); in bound phenolic extracts, EC50 values showed strong negative associations with phenolic contents (r = −0.869, p < 0.05) and ORAC values (r = −0.918, p < 0.01). Moreover, the contents of free phenolics were higher than that of the bound phenolics, and the three black sesame seeds generally depicted higher total phenolics compared to the three white varieties. The antioxidant (ORAC values) and antiproliferation activities of six sesame seeds were both associated with contents of bound phenolics (r > 0.8, p < 0.05). Interestingly, nonlignan components in bound phenolics contributed to the antioxidant and antiproliferative activities. This study suggested that Fenheizhi3 variety is superior to the other five varieties as antioxidant supplements. PMID:27597975

A preliminary look at AVE-SESAME 3 conducted on 25-26 April 1979

NASA Technical Reports Server (NTRS)

Williams, S. F.; Horvath, N.; Turner, R. E.

1980-01-01

General weather conditions, including synoptic maps, radar reports, satellite photographs, precipitation areas and amounts, and a summary of severe weather reports are presented. These data provide researchers a preliminary look at conditions during the AVE-SESAME 3 period.

CEO stabilization of a femtosecond laser using a SESAM as fast opto-optical modulator.

PubMed

Hoffmann, Martin; Schilt, Stéphane; Südmeyer, Thomas

2013-12-02

We present a new method for intra-cavity control of the carrier-envelope offset (CEO) frequency of ultrafast lasers that combines high feedback bandwidth with low loss, low nonlinearity, and low dispersion. A semiconductor saturable-absorber mirror (SESAM) inside a modelocked laser is optically pumped with a continuous-wave (cw) laser. In this way, the SESAM acts as intra-cavity opto-optical modulator (OOM): the optical power of the cw-laser corresponds to a high-bandwidth modulation channel for CEO frequency control. We experimentally verified this method for a femtosecond Er:Yb:glass oscillator (ERGO), in which one SESAM is in parallel used for modelocking and as intra-cavity OOM for achieving a tight CEO lock. This laser can also be CEO-stabilized in the usual scheme, in which the laser pump current is modulated, i.e., the gain element acts as intra-cavity OOM. We compare the performance with gain and SESAM OOM measuring CEO transfer function, frequency noise power spectral density (PSD), and Allan deviation for integration times up to 1000 s. In the case of the gain OOM, the millisecond upper-state lifetime of the Er:Yb:glass limits the achievable CEO-control bandwidth to <10 kHz. The feedback bandwidth of the SESAM OOM was more than a factor of 10 higher than the gain OOM bandwidth and was mainly limited by the used current driver. The residual integrated phase noise (1 Hz - 100 kHz) of the ~20-MHz CEO beat was improved by more than an order of magnitude (from 720 mrad to less than 65 mrad), and the fractional frequency stability by a factor of 4 (from 1∙10

Seven Essential Elements for Creating Effective Children's Media to Promote Peacebuilding: Lessons from International Coproductions of Sesame Street and Other Children's Media Programs.

PubMed

Cole, Charlotte F; Lee, June H; Bucuvalas, Abigail; Sırali, Yasemin

2018-03-01

Children's media have the capacity to prepare young learners to develop the knowledge, attitudes, and skills they need to contribute to a more peaceful world. Research suggests international coproductions of Sesame Street and other children's media efforts are linked to positive impact on how viewers perceive themselves and their own cultures, as well as how they perceive others. Creating such media, however, relies on a commitment to a complex development process where the educational needs of children are considered alongside intra- and intergroup dynamics and political realities. This paper presents a practitioners' perspective on the essential components of children's media programs for peacebuilding and, in so doing, recommends a way forward for producing children's media in this domain. © 2018 Wiley Periodicals, Inc.

A preliminary look at AVE-SESAME 4 conducted on 9-10 May 1979

NASA Technical Reports Server (NTRS)

July, M.; Turner, R. E.

1980-01-01

This report contains information on data collected, symptotic conditions, and severe and unusual weather reported during the Atmospheric Variability Experiment Severe Environmental Storms and Mesoscale Experiment (AVE-SESAME) 4 period. The information provides researchers a look at conditions during the period.

40 CFR 180.151 - Ethylene oxide; tolerances for residues.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances..., except basil 7 Licorice, roots 7 Peppermint, tops, dried 7 Sesame, seed 7 Spearmint, tops, dried 7... 19, dried, except basil 940 Licorice, roots 940 Peppermint, tops, dried 940 Sesame, seed 940...

40 CFR 180.151 - Ethylene oxide; tolerances for residues.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances..., except basil 7 Licorice, roots 7 Peppermint, tops, dried 7 Sesame, seed 7 Spearmint, tops, dried 7... 19, dried, except basil 940 Licorice, roots 940 Peppermint, tops, dried 940 Sesame, seed 940...

40 CFR 180.151 - Ethylene oxide; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances..., except basil 7 Licorice, roots 7 Peppermint, tops, dried 7 Sesame, seed 7 Spearmint, tops, dried 7... 19, dried, except basil 940 Licorice, roots 940 Peppermint, tops, dried 940 Sesame, seed 940...

40 CFR 180.151 - Ethylene oxide; tolerances for residues.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances..., except basil 7 Licorice, roots 7 Peppermint, tops, dried 7 Sesame, seed 7 Spearmint, tops, dried 7... 19, dried, except basil 940 Licorice, roots 940 Peppermint, tops, dried 940 Sesame, seed 940...

40 CFR 180.151 - Ethylene oxide; tolerances for residues.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances..., except basil 7 Licorice, roots 7 Peppermint, tops, dried 7 Sesame, seed 7 Spearmint, tops, dried 7... 19, dried, except basil 940 Licorice, roots 940 Peppermint, tops, dried 940 Sesame, seed 940...

Sesame Street; 1,000 Hours of a Perpetual Television Experiment.

ERIC Educational Resources Information Center

Cooney, Joan Ganz

During its seven year history, "Sesame Street" has maintained high popularity while introducing such innovations as new cognitive curricula, new characters, bilingual elements, and affective and social education. Early goals emphasized 40 predominantly cognitive objectives aimed at helping the disadvantaged child. Additions have included…

"Shalom Sesame": Using Media to Promote Jewish Education and Identity

ERIC Educational Resources Information Center

Fisch, Shalom M.; Lemish, Dafna; Spezia, Elizabeth; Siegel, Deborah; Fisch, Susan R. D.; Aladé, Fashina; Kasdan, Daniel

2013-01-01

A family survey, ethnographic study, and quasi-experimental study investigated "Shalom Sesame's" potential to enhance understanding of Jewish culture and identity among preschool families. Preschoolers demonstrated significant learning, recognizing that people who looked different could be Jewish, and in knowledge about Hebrew words,…

"Sesame Street": A Linguistic Detour for Black-Language Speakers

ERIC Educational Resources Information Center

Stewart, Barbara H.

1973-01-01

Maintains that the concept of verbal deprivation'' constituting an integral part of the operating assumption of Sesame Street'' has been thoroughly refuted by reputed liguists; that nonstandard'' English is not an inept, deficient approximation of American English but a separate, logical, and highly structured system of communication. (RJ)

Neural activity during natural viewing of Sesame Street statistically predicts test scores in early childhood.

PubMed

Cantlon, Jessica F; Li, Rosa

2013-01-01

It is not currently possible to measure the real-world thought process that a child has while observing an actual school lesson. However, if it could be done, children's neural processes would presumably be predictive of what they know. Such neural measures would shed new light on children's real-world thought. Toward that goal, this study examines neural processes that are evoked naturalistically, during educational television viewing. Children and adults all watched the same Sesame Street video during functional magnetic resonance imaging (fMRI). Whole-brain intersubject correlations between the neural timeseries from each child and a group of adults were used to derive maps of "neural maturity" for children. Neural maturity in the intraparietal sulcus (IPS), a region with a known role in basic numerical cognition, predicted children's formal mathematics abilities. In contrast, neural maturity in Broca's area correlated with children's verbal abilities, consistent with prior language research. Our data show that children's neural responses while watching complex real-world stimuli predict their cognitive abilities in a content-specific manner. This more ecologically natural paradigm, combined with the novel measure of "neural maturity," provides a new method for studying real-world mathematics development in the brain.

Sesamin and sesamolin as unexpected contaminants in various cold-pressed plant oils: NP-HPLC/FLD/DAD and RP-UPLC-ESI/MS(n) study.

PubMed

Górnaś, Paweł; Siger, Aleksander; Pugajeva, Iveta; Segliņa, Dalija

2014-04-01

Thirteen cold-pressed oils (Japanese quince seed, black caraway, flaxseed, rapeseed, hemp, peanut, sunflower, pumpkin, hazelnut, poppy, walnut, almond and sesame oil) manufactured by the same company over a 2-year period (2011-12) were assessed for lipophilic compounds. The presence of sesamin and sesamolin, two characteristic lignans of sesame oil, were detected in all tested plant oils. Both lignans were identified by NP-HPLC/FLD/DAD and confirmed by a RP-UPLC-ESI/MS(n) method. The lowest amount of sesamin and sesamolin was found for Japanese quince seed oil (0.10 and 0.27 mg/100 g), and the highest, excluding sesame oil, for almond oil (36.21 and 105.42 mg/100 g, respectively). The highly significant correlation between sesamolin and sesamin concentrations was found in all samples tested (r = 0.9999; p < 0.00001). These results indicate contamination of cold-pressed oils from the same source. This investigation highlights the fact that increasing the range of products manufactured by the same company can contribute to a lesser regard for the quality of the final product. Moreover, less attention paid to the quality of final product can be related to the health risks of consumers especially sensitive to allergens. Therefore, proper cleaning of processing equipment is needed to prevent cross-contact of cold-pressed oils.

The use of stereoscopic satellite observation in the determination of the emissivity of cirrus

NASA Astrophysics Data System (ADS)

Szejwach, G.; Sletten, T. N.; Hasler, A. F.

The feasibility of determining cirrus ``emissivity'' from combined stereoscopic and infrared satellite observations in conjunction with radiosounding data is investigated for a particular case study. Simultaneous visible images obtained during SESAME-1979 from two geosynchronous GOES meteorological satellites were processed on the NASA/Goddard interactive system (AOIPS) and were used to determine the stereo cloud top height ZC as described by Hasler [1]. Iso-contours of radiances were outlined on the corresponding infrared image. Total brightness temperature TB and ground surface brightness temperature TS were inferred from the radiances. The special SESAME network of radiosoundings was used to determine the cloud top temperature TCLD at the level defined by ZC. The ``effective cirrus emissivity'' NE where N is the fractional cirrus cloudiness and E is the emissivity in a GOES infrared picture element of about 10 km × 10 km is then computed from TB, TS and TCLD.

7 CFR 1421.107 - Warehouse receipts.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Mustard Seed: 10.0 percent; (4) Rapeseed: 10.0 percent; (5) Safflower Seed: 10.0 percent; (6) Sunflower Seed: 10.0 percent; (7) Crambe: 10.0 percent; and (8) Sesame Seed: 10.0 percent. (i)(1) If, under..., such certificate must state that no lien for processing will be asserted by the warehouse operator...

7 CFR 1421.107 - Warehouse receipts.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) Mustard Seed: 10.0 percent; (4) Rapeseed: 10.0 percent; (5) Safflower Seed: 10.0 percent; (6) Sunflower Seed: 10.0 percent; (7) Crambe: 10.0 percent; and (8) Sesame Seed: 10.0 percent. (i)(1) If, under..., such certificate must state that no lien for processing will be asserted by the warehouse operator...

7 CFR 1421.107 - Warehouse receipts.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Mustard Seed: 10.0 percent; (4) Rapeseed: 10.0 percent; (5) Safflower Seed: 10.0 percent; (6) Sunflower Seed: 10.0 percent; (7) Crambe: 10.0 percent; and (8) Sesame Seed: 10.0 percent. (i)(1) If, under..., such certificate must state that no lien for processing will be asserted by the warehouse operator...

7 CFR 1421.107 - Warehouse receipts.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Mustard Seed: 10.0 percent; (4) Rapeseed: 10.0 percent; (5) Safflower Seed: 10.0 percent; (6) Sunflower Seed: 10.0 percent; (7) Crambe: 10.0 percent; and (8) Sesame Seed: 10.0 percent. (i)(1) If, under..., such certificate must state that no lien for processing will be asserted by the warehouse operator...

7 CFR 1421.107 - Warehouse receipts.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Mustard Seed: 10.0 percent; (4) Rapeseed: 10.0 percent; (5) Safflower Seed: 10.0 percent; (6) Sunflower Seed: 10.0 percent; (7) Crambe: 10.0 percent; and (8) Sesame Seed: 10.0 percent. (i)(1) If, under..., such certificate must state that no lien for processing will be asserted by the warehouse operator...

SESAME: science for intercultural dialogue

NASA Astrophysics Data System (ADS)

Paolucci, Giorgio

2015-04-01

SESAME is an international research organization located in Jordan, in the Middle-East. Based on a synchrotron radiation source, it will allow scientist from the region to access a world-class research infrastructure to boost their research and scientific knowledge. At the same time its international nature will allow scientists with different cultures, different religions and different experiences to interact with each other. It is therefore an excellent opportunity for the regional development. The talk will introduce synchrotron radiation as a method to study matter, with examples in various disciplines, from physics to life sciences. The organisational structure of SESAME will be described, emphasising how this project is expected to enhance cooperation and mutual comprehension in the Middle East.

Localizing Play-Based Pedagogy: Nigerian Educators' Appropriation of Sesame Classroom Materials

ERIC Educational Resources Information Center

Moland, Naomi A.

2017-01-01

This article examines how international organizations promote play-based pedagogical approaches in early childhood settings around the world, and how local educators respond. As a case study, I investigated Sesame Workshop's efforts to introduce play-based approaches in Nigerian classrooms. In addition to producing a Nigerian version of…

The MGGB equation-of-state for multifield applications: a numerical recipe for analytic expression of sesame EOS data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kashiwa, B. A.

2010-12-01

Abstract A thermodynamically consistent and fully general equation–of– state (EOS) for multifield applications is described. EOS functions are derived from a Helmholtz free energy expressed as the sum of thermal (fluctuational) and collisional (condensed–phase) contributions; thus the free energy is of the Mie–Gr¨uneisen1 form. The phase–coexistence region is defined using a parameterized saturation curve by extending the form introduced by Guggenheim,2 which scales the curve relative to conditions at the critical point. We use the zero–temperature condensed–phase contribution developed by Barnes,3 which extends the Thomas–Fermi–Dirac equation to zero pressure. Thus, the functional form of the EOS could be called MGGBmore » (for Mie– Gr¨uneisen–Guggenheim–Barnes). Substance–specific parameters are obtained by fitting the low–density energy to data from the Sesame4 library; fitting the zero–temperature pressure to the Sesame cold curve; and fitting the saturation curve and latent heat to laboratory data,5 if available. When suitable coexistence data, or Sesame data, are not available, then we apply the Principle of Corresponding States.2 Thus MGGB can be thought of as a numerical recipe for rendering the tabular Sesame EOS data in an analytic form that includes a proper coexistence region, and which permits the accurate calculation of derivatives associated with compressibility, expansivity, Joule coefficient, and specific heat, all of which are required for multifield applications. 1« less

First-principles equation-of-state table of silicon and its effects on high-energy-density plasma simulations

NASA Astrophysics Data System (ADS)

Hu, S. X.; Gao, R.; Ding, Y.; Collins, L. A.; Kress, J. D.

2017-04-01

Using density-functional theory-based molecular-dynamics simulations, we have investigated the equation of state for silicon in a wide range of plasma density and temperature conditions of ρ =0.001 -500 g /c m3 and T =2000 -108K . With these calculations, we have established a first-principles equation-of-state (FPEOS) table of silicon for high-energy-density (HED) plasma simulations. When compared with the widely used SESAME-EOS model (Table 3810), we find that the FPEOS-predicted Hugoniot is ˜20% softer; for off-Hugoniot plasma conditions, the pressure and internal energy in FPEOS are lower than those of SESAME EOS for temperatures above T ≈ 1-10 eV (depending on density), while the former becomes higher in the low-T regime. The pressure difference between FPEOS and SESAME 3810 can reach to ˜50%, especially in the warm-dense-matter regime. Implementing the FPEOS table of silicon into our hydrocodes, we have studied its effects on Si-target implosions. When compared with the one-dimensional radiation-hydrodynamics simulation using the SESAME 3810 EOS model, the FPEOS simulation showed that (1) the shock speed in silicon is ˜10% slower; (2) the peak density of an in-flight Si shell during implosion is ˜20% higher than the SESAME 3810 simulation; (3) the maximum density reached in the FPEOS simulation is ˜40% higher at the peak compression; and (4) the final areal density and neutron yield are, respectively, ˜30% and ˜70% higher predicted by FPEOS versus the traditional simulation using SESAME 3810. All of these features can be attributed to the larger compressibility of silicon predicted by FPEOS. These results indicate that an accurate EOS table, like the FPEOS presented here, could be essential for the precise design of targets for HED experiments.

First-principles equation-of-state table of silicon and its effects on high-energy-density plasma simulations

DOE PAGES

Hu, S. X.; Gao, R.; Ding, Y.; ...

2017-04-21

Using density-functional theory–based molecular-dynamics simulations, we have investigated the equation of state for silicon in a wide range of plasma density and temperature conditions of ρ=0.001–500g/cm 3 and T=2000–10 8K. With these calculations, we have established a first-principles equation-of-state (FPEOS) table of silicon for high-energy-density (HED) plasma simulations. When compared with the widely used SESAME-EOS model (Table 3810), we find that the FPEOS-predicted Hugoniot is ~20% softer; for off-Hugoniot plasma conditions, the pressure and internal energy in FPEOS are lower than those of SESAME EOS for temperatures above T ≈ 1–10 eV (depending on density), while the former becomes highermore » in the low- T regime. The pressure difference between FPEOS and SESAME 3810 can reach to ~50%, especially in the warm-dense-matter regime. Implementing the FPEOS table of silicon into our hydrocodes, we have studied its effects on Si-target implosions. When compared with the one-dimensional radiation-hydrodynamics simulation using the SESAME 3810 EOS model, the FPEOS simulation showed that (1) the shock speed in silicon is ~10% slower; (2) the peak density of an in-flight Si shell during implosion is ~20% higher than the SESAME 3810 simulation; (3) the maximum density reached in the FPEOS simulation is ~40% higher at the peak compression; and (4) the final areal density and neutron yield are, respectively, ~30% and ~70% higher predicted by FPEOS versus the traditional simulation using SESAME 3810. All of these features can be attributed to the larger compressibility of silicon predicted by FPEOS. Furthermore, these results indicate that an accurate EOS table, like the FPEOS presented here, could be essential for the precise design of targets for HED experiments.« less

First-principles equation-of-state table of silicon and its effects on high-energy-density plasma simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, S. X.; Gao, R.; Ding, Y.

Using density-functional theory–based molecular-dynamics simulations, we have investigated the equation of state for silicon in a wide range of plasma density and temperature conditions of ρ=0.001–500g/cm 3 and T=2000–10 8K. With these calculations, we have established a first-principles equation-of-state (FPEOS) table of silicon for high-energy-density (HED) plasma simulations. When compared with the widely used SESAME-EOS model (Table 3810), we find that the FPEOS-predicted Hugoniot is ~20% softer; for off-Hugoniot plasma conditions, the pressure and internal energy in FPEOS are lower than those of SESAME EOS for temperatures above T ≈ 1–10 eV (depending on density), while the former becomes highermore » in the low- T regime. The pressure difference between FPEOS and SESAME 3810 can reach to ~50%, especially in the warm-dense-matter regime. Implementing the FPEOS table of silicon into our hydrocodes, we have studied its effects on Si-target implosions. When compared with the one-dimensional radiation-hydrodynamics simulation using the SESAME 3810 EOS model, the FPEOS simulation showed that (1) the shock speed in silicon is ~10% slower; (2) the peak density of an in-flight Si shell during implosion is ~20% higher than the SESAME 3810 simulation; (3) the maximum density reached in the FPEOS simulation is ~40% higher at the peak compression; and (4) the final areal density and neutron yield are, respectively, ~30% and ~70% higher predicted by FPEOS versus the traditional simulation using SESAME 3810. All of these features can be attributed to the larger compressibility of silicon predicted by FPEOS. Furthermore, these results indicate that an accurate EOS table, like the FPEOS presented here, could be essential for the precise design of targets for HED experiments.« less

Measuring the permittivity of the surface of the Churyumov-Gerasimenko nucleus: the PP-SESAME experiment on board the Philae/ROSETTA lander

NASA Astrophysics Data System (ADS)

Lethuillier, A.; Le Gall, A. A.; Hamelin, M.; Ciarletti, V.; Caujolle-Bert, S.; Schmidt, W.; Grard, R.

2014-12-01

Within Philae, the lander of the Rosetta spacecraft, the Permittivity Probe (PP) experiment as part of the Surface Electric Sounding and Acoustic Monitoring Experiment (SESAME) package was designed to measure the low frequency (Hz-kHz) electrical properties of the close subsurface of the nucleus.At frequencies below 10 kHz, the electrical signature of the matter is especially sensitive to the presence of water ice and its temperature. PP-SESAME will thus allow to determine the water ice content in the near-surface and to monitor its diurnal and orbital variations thus providing essential insight on the activity and evolution of the cometary nucleus.The PP-SESAME instrument is derived from the quadrupole array technique. A sinusoidal electrical current is sent into the ground through a first dipole, and the induced electrical voltage is measured with a second dipole. The complex permittivity of the material is inferred from the mutual impedance derived from the measurements. In practice, the influence of both the electronic circuit of the instrument and the conducting elements in its close environment must be accounted for in order to best estimate the dielectric constant and electric conductivity of the ground. To do this we have developed a method called the "capacity-influence matrix method".A replica of the instrument was recently built in LATMOS (France) and was tested in the frame of a field campaign in the giant ice cave system of Dachstein, Austria. In the caves, the ground is covered with a thick layer of ice, which temperature is rather constant throughout the year. This measurement campaign allowed us to test the "capacity influence matrix method" in a natural icy environment.The first measurements of the PP-SESAME/Philae experiment should be available in mid-November. In this paper we will present the "capacity-influence matrix method", the measurements and results from the Austrian field campaign and the preliminary analysis of the PP-SESAME/Philae data.

Analysis of Sesame Marketing Chain in Case of Gimbi Districts, Ethiopia

ERIC Educational Resources Information Center

Temesgen, Fikru; Gobena, Efa; Megersa, Hailu

2017-01-01

This study was aimed at marketing chain of sesames in Gimbi Woredas of Oromia Region with specific objectives of identifying marketing channels and factors affecting outlet choice decisions of farm households. The data were collected from both primary and secondary sources. The primary data for this study were collected from 127 farmers, 17…

"Sesame Street" Puts Self-Regulation Skills at the Core of School Readiness

ERIC Educational Resources Information Center

Truglio, Rosemarie T; Stefano, Autumn Zitani; Sanders, Jennifer Schiffman

2014-01-01

Self-regulation is the ability to control one's thoughts, actions, and emotions. When children are better able to follow directions or control impulses they are better prepared for school and for life. Sesame Workshop has and continues to create rich, meaningful content that places self-regulation skills and the strategies needed for school…

The Lives of Sesame Street: The Impact of Foreclosures on Young Children and Families

ERIC Educational Resources Information Center

Davis, Danne E.; Shin, Minsun

2009-01-01

While significant attention has been paid to Wall Street investors and families impacted by the current subprime mortgage crisis in the USA, the lives of Sesame Street are minimally discussed. Children and their families are enduring a variety of consequences of foreclosures. The consequences can be hugely disruptive to the approximately 2 million…

Assessment of the aroma impact of major odor-active thiols in pan-roasted white sesame seeds by calculation of odor activity values.

PubMed

Tamura, Hitoshi; Fujita, Akira; Steinhaus, Martin; Takahisa, Eisuke; Watanabe, Hiroyuki; Schieberle, Peter

2011-09-28

Eleven odor-active thiols, namely, 2-methyl-1-propene-1-thiol, (Z)-3-methyl-1-butene-1-thiol, (E)-3-methyl-1-butene-1-thiol, (Z)-2-methyl-1-butene-1-thiol, (E)-2-methyl-1-butene-1-thiol, 2-methyl-3-furanthiol, 3-mercapto-2-pentanone, 2-mercapto-3-pentanone, 4-mercapto-3-hexanone, 3-mercapto-3-methylbutyl formate, and 2-methyl-3-thiophenethiol, recently identified in an extract prepared from white sesame seeds, were quantitated in sesame using stable isotope dilution analyses. For that purpose, the following deuterium-labeled compounds were synthesized and used as internal standards in the quantitation assays: [2H6]-2-methyl-1-propene-1-thiol, [2H3]-(E)- and [2H3]-(Z)-2-methyl-1-butene-1-thiol, [2H3]-2-methyl-3-furanthiol, [2H2]-3-mercapto-2-pentanone, [2H3]-4-mercapto-3-hexanone, [2H6]-3-mercapto-3-methylbutyl formate, and [2H3]-2-methyl-3-thiophenethiol. On the basis of the results obtained, odor activity values (OAVs) were calculated as ratio of the concentration and odor threshold of the individual compounds in cooking oil. According to their high OAVs, particularly the 3-methyl-1-butene-1-thiols (OAV: 2400) and the 2-methyl-1-butene-1-thiols (OAV: 960) were identified as the most odor-active compounds in pan-roasted white sesame seeds. These compounds were therefore suggested to be mainly responsible for the characteristic but rather unstable sulfury aroma of freshly pan-roasted white sesame seeds.

A kinetic study on sesame cake protein hydrolysis by Alcalase.

PubMed

Demirhan, Elçin; Apar, Dilek Kılıç; Özbek, Belma

2011-01-01

In the present study, the hydrolysis of sesame cake protein was performed by Alcalase, a bacterial protease produced by Bacillus licheniformis, to investigate the reaction kinetics of sesame cake hydrolysis and to determine decay and product inhibition effects for Alcalase. The reactions were carried out for 10 min in 0.1 L of aqueous solutions containing 10, 15, 20, 25, and 30 g protein/L at various temperature and pH values. To determine decay and product inhibition effects for Alcalase, a series of inhibition experiments were conducted with the addition of various amounts of hydrolysate. The reaction kinetics was investigated by initial rate approach. The initial reaction rates were determined from the slopes of the linear models that fitted to the experimental data. The kinetic parameters, K(m) and V(max), were estimated as 41.17 g/L and 9.24 meqv/L x min. The Lineweaver-Burk plots showed that the type of inhibition for Alcalase determined as uncompetitive, and the inhibition constant, K(i), was estimated as 38.24% (hydrolysate/substrate mixture). Practical Application: Plant proteins are increasingly being used as an alternative to proteins from animal sources to perform functional roles in food formulation. Knowledge of the kinetics of the hydrolysis reaction is essential for the optimization of enzymatic protein hydrolysis and for increasing the utilization of plant proteins in food products. Therefore, in the present study, the hydrolysis of sesame cake protein was performed by Alcalase, a bacterial protease produced by B. licheniformis, to investigate the reaction kinetics of sesame cake hydrolysis and to determine decay and product inhibition effects for Alcalase.

Lead biotransformation potential of allochthonous Bacillus sp. SKK11 with sesame oil cake in mine soil

USDA-ARS?s Scientific Manuscript database

This study was aimed at assessing the potential of allochthonous Bacillus sp. SKK11 and sesame oil cake extract for transformation of Pb in mine soil. The bacteria were isolated from a brackish environment and identified as Bacillus sp. based on partial 16S rDNA sequences. The isolate SKK11 exhibite...

Starck Ta PTW strength model recommendation for use with SESAME 93524 EoS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjue, Sky K.; Prime, Michael Bruce

2017-02-27

The purpose of this document is to provide a calibration of the Preston-Tonks- Wallace (PTW) strength model for use with the new SESAME equation of state (EoS) 93524. The calibration data included in this t spans temperatures from 198 K to 673 K and strain rates from 0.001/s to 3200/s.

SESAME, A 3rd Generation Synchrotron Light Source for the Middle East

DOE Office of Scientific and Technical Information (OSTI.GOV)

Einfeld, D.; Hasnain, S.S.; Sayers, Z.

2004-05-12

Developed under the auspices of UNESCO, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be a major international research centre in the Middle East and Mediterranean region. On 6th of January 2003, the official foundation of SESAME took place. The facility is located in Allan, Jordan, 30 km North-West of Amman. As of August 2003 the Founding Members are Bahrain, Egypt, Iran, Israel, Jordan, Pakistan, Palestine, Turkey and United Arabic Emirates, representing a population of over 300 million. SESAME will be a 2.5 GeV 3rd Generation light source (emittance 24.6 nm.rad, circumference {approx}125m). About 40% ofmore » the circumference is available for insertion devices (average length 2.75m) in 13 straight sections. Beam lines are up to 36m. The site and a building are provided by Jordan. Construction started in August 2003. The scientific program will start with up to 6 beam lines: MAD Protein Crystallography, SAXS and WAXS for polymers and proteins, Powder Diffraction for material science, UV/VUV/SXR Photoelectron Spectroscopy and Photoabsorption Spectroscopy, IR Spectroscopy, and EXAFS.« less

Experimental Research in TV Instruction. Proceedings of an International Conference (2nd, St. John's, Newfoundland, Canada, June 21-23, 1979). [Volume 2.

ERIC Educational Resources Information Center

Baggaley, Jon, Ed.; Sharpe, Joan, Ed.

A foreword by Arthur M. Sullivan and an introduction by Jon P. Baggaley introduce the 12 conference papers included in this collection. The papers are as follows: (1) "Research on 'Sesame Street': Designing the Educational Context" (Rodney Dennis); (2) "'Sesame Street' in Labrador" (Graham Skanes and Lorne Taylor); (3)…

A kinetic energy study of the meso beta-scale storm environment during AVE-SESAME 5 (20-21 May 1979)

NASA Technical Reports Server (NTRS)

Printy, M. F.; Fuelberg, H. E.

1984-01-01

Kinetic energy of the near storm environment was analyzed by meso beta scale data. It was found that horizontal winds in the 400 to 150 mb layer strengthen rapidly north of the developing convection. Peak values then decrease such that the maximum disappears 6 h later. Southeast of the storms, wind speeds above 300 mb decrease nearly 50% during the 3 h period of most intense thunderstorm activity. When the convection dissipates, wind patterns return to prestorm conditions. The mesoscale storm environment of AVE-SESAME 5 is characterized by large values of cross contour generation of kinetic energy, transfers of energy to nonresolvable scales of motion, and horizontal flux divergence. These processes are maximized within the upper troposphere and are greatest during times of strongest convection. It is shown that patterns agree with observed weather features. The southeast area of the network is examined to determine causes for vertical wind variations.

Effects of Sesame (Sesamum indicum L.) Supplementation on Creatine Kinase, Lactate Dehydrogenase, Oxidative Stress Markers, and Aerobic Capacity in Semi-Professional Soccer Players

PubMed Central

Barbosa, Carlos V. da Silva; Silva, Alexandre S.; de Oliveira, Caio V. C.; Massa, Nayara M. L.; de Sousa, Yasmim R. F.; da Costa, Whyara K. A.; Silva, Ayice C.; Delatorre, Plínio; Carvalho, Rhayane; Braga, Valdir de Andrade; Magnani, Marciane

2017-01-01

Nutritional intervention with antioxidants rich foods has been considered a strategy to minimize the effects of overtraining in athletes. This experimental, randomized, and placebo-controlled study evaluated the effects of consumption of sesame (Sesamum indicum L.) on muscle damage markers, oxidative stress, systemic inflammation, and aerobic performance in male semi-professional soccer players. Twenty athletes were randomly assigned to groups that received 40 g (two tablespoons) per day of sesame or a placebo during 28 days of regular training (exposed to routine training that includes loads of heavy training in the final half of the season). Before and after intervention, creatine kinase (CK), lactate dehydrogenase (LDH), malondialdehyde (MDA), superoxide dismutase (SOD), C-reactive protein (hs-CRP), and aerobic capacity were evaluated. Before intervention, a physiologic imbalance was noted in both groups related to CK and LDH levels. Sesame intake caused a reduction of CK (19%, p < 0.05), LDH (37%, p < 0.05), MDA (55%, p < 0.05) and hs-CRP (53%, p < 0.05) and increased SOD (14%, p < 0.05), vitamin A (25%, p < 0.05), and vitamin E (65%, p < 0.05) in the experimental group. These phenomena were accompanied by increased aerobic capacity (17%, p < 0.05). The placebo group showed an increase in CK (5%, p < 0.05) and no significant change in LDH, SOD or vitamin A. MDA levels decreased (21%, p < 0.05) and vitamin E increased (14%, p < 0.05) in the placebo group, but to a much lesser extent than in the experimental group. These results show that sesame consumption may reduce muscle damage and oxidative stress while improving the aerobic capacity in soccer players. PMID:28408889

Measuring the Permittivity of the Nucleus of a Comet: the PP-SESAME Experiment on Board the Philae/ROSETTA Lander

NASA Astrophysics Data System (ADS)

Lethuillier, A.; Le Gall, A. A.; Hamelin, M.; Ciarletti, V.; Caujolle-Bert, S.; Schmidt, W.; Grard, R.; Seidensticker, K. J.; Fischer, H. H.

2015-12-01

The Permittivity Probe (SESAME-PP) on-board the Philae Lander of the ROSETTA mission was designed to constrain the complex permittivity of the first 2 m of the nucleus of comet 67P/Churyumov-Gerasimenko and to monitor its variations with time. Doing so, it is meant to provide a unique insight into the composition of the comet, and in particular, into its water content. PP-SESAME acquired data on November 13, 2015, both during Philae descent to the comet and at the surface of the nucleus. The PP-SESAME instrument is derived from the quadrupole array technique. A sinusoidal electrical current is sent into the ground through a transmitting dipole, and the induced electrical voltage on a receiving dipole is measured. The complex permittivity of the material is inferred from the mutual impedance derived from the measurements. In practice, the influence of both the electronic circuit of the instrument and the conducting elements in its close environment must be accounted for in order to best estimate both the dielectric constant and electrical conductivity of the ground. For that purpose, we have developed a method called the "capacity-influence matrix method". A replica of the instrument was recently built in LATMOS (France) in order to validate this method. In this paper, we will present the tests conducted with the replica in a controlled environment and their comparison to numerical simulations. We will also show simulations relevant to the PP-SESAME experiment on the nucleus of comet 67P/Churyumov-Gerasimenko. These simulations were run for realistic scenarios of the Philae's attitude and environment at its final landing site. We discuss their implications in terms of surface electrical and compositional properties.

On the reliability of the CD123-endowed basophil activation test (BAT) and its application in food allergy.

PubMed

Chirumbolo, Salvatore; Bjørklund, Geir; Vella, Antonio

2018-06-15

the recent paper by Appel et al., evaluated the use of the basophil activaion test (BAT) in sesame allergy and concluded that BAT should be preferentially used in association with high protein sesame extract-skin prick test (HSPE-SPT) for the diagnosis of sesame food allergy, so preventing any ethical issue regarding the possble risk associated with oral food challenge (OFC) 1 . The authors used a non commercial BAT approach endowed with the CD123 pos /HLADR neg phenotyping protocol and using CD63 and/or CD203c as activation markers 2,3 . Basophils were initially captured in flow cytometry (FC) from a not clearly separated side scatter (SSC)-CD123 pos . This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The Success Factors to Defeat Insurgency in the Philippines and Its Applicability in the Colombian Context

DTIC Science & Technology

2013-12-01

airport. 174. The main agricultural products in Colombia are rice, barley, corn, wheat, sorghum, sesame, cotton, soy, kidney bean, potato, banana ...cocoa, sugar cane, tobacco, oil palm, vegetables, fruits and flowers . Agro-industrial production crops predominate over of food crops. The forest...of poverty, misery, social inequality, 223. Domestic consumer products: rice, barley, corn, wheat, sorghum, sesame, cotton, soybeans, beans, bananas

A Report on the Role and Penetration of Sesame Street in Ghetto Communities (Bedford Stuyvesant, East Harlem, Chicago and Washington, D.C.).

ERIC Educational Resources Information Center

Children's Television Workshop, New York, NY.

Three major themes dominated the results of a 1973 survey conducted for the Children's Television Workshop in ghetto areas of New York, Chicago, and Washington, D.C. First, comparison of survey data with data from studies conducted in 1970 and 1971 showed that Sesame Street had become an institution with ghetto children, its penetration and…

Seven Essential Elements for Creating Effective Children's Media to Promote Peacebuilding: Lessons from International Coproductions of Sesame Street and Other Children's Media Programs

ERIC Educational Resources Information Center

Cole, Charlotte F.; Lee, June H.; Bucuvalas, Abigail; Sirali, Yasemin

2018-01-01

Children's media have the capacity to prepare young learners to develop the knowledge, attitudes, and skills they need to contribute to a more peaceful world. Research suggests international coproductions of Sesame Street and other children's media efforts are linked to positive impact on how viewers perceive themselves and their own cultures, as…

Assessment of the microbiological safety of edible dried seeds from retail premises in the United Kingdom with a focus on Salmonella spp.

PubMed

Willis, Caroline; Little, Christine L; Sagoo, Satnam; de Pinna, Elizabeth; Threlfall, John

2009-12-01

Sesame seed products have recently been associated with a number of Salmonella outbreaks in the UK and elsewhere. Aside from sesame seeds, there is little published information on the prevalence of Salmonella spp. in edible seeds. A study of 3735 samples of retail edible dried seeds in the UK was therefore carried out between October 2007 and March 2008 to assess their microbiological safety in relation to Salmonella contamination and levels of Escherichia coli, an indicator of faecal contamination. Overall, Salmonella was detected in 23 samples (0.6%), of which over half (57%) were sesame seeds. Other seeds contaminated with Salmonella were linseed (1 sample), sunflower (1 sample), alfalfa (1 sample), melon (4 samples) and mixed seeds (3 samples). E. coli was detected in 9% of samples, with 1.5% containing unsatisfactory levels (> or = 10(2)/g). These included melon, pumpkin, sesame, hemp, poppy, linseed, sunflower and mixed seeds. The UK retailers affected by the detection of Salmonella in their products recalled the contaminated batches, and Food Standards Agency food alerts were issued to advise against the consumption of affected seed products. This study highlights the importance of good hygiene practices and effective decontamination procedures during the production of these products.

Identification of novel aroma-active thiols in pan-roasted white sesame seeds.

PubMed

Tamura, Hitoshi; Fujita, Akira; Steinhaus, Martin; Takahisa, Eisuke; Watanabe, Hiroyuki; Schieberle, Peter

2010-06-23

Screening for aroma-active compounds in an aroma distillate obtained from freshly pan-roasted sesame seeds by aroma extract dilution analysis revealed 32 odorants in the FD factor range of 2-2048, 29 of which could be identified. The highest FD factors were found for the coffee-like smelling 2-furfurylthiol, the caramel-like smelling 4-hydroxy-2,5-dimethyl-3(2H)-furanone, the coffee-like smelling 2-thenylthiol (thiophen-2-yl-methylthiol), and the clove-like smelling 2-methoxy-4-vinylphenol. In addition, 9 odor-active thiols with sulfurous, meaty, and/or catty, black-currant-like odors were identified for the first time in roasted sesame seeds. Among them, 2-methyl-1-propene-1-thiol, (Z)-3-methyl-1-butene-1-thiol, (E)-3-methyl-1-butene-1-thiol, (Z)-2-methyl-1-butene-1-thiol, (E)-2-methyl-1-butene-1-thiol, and 4-mercapto-3-hexanone were previously unknown as food constituents. Their structures were confirmed by comparing their mass spectra and retention indices as well as their sensory properties with those of synthesized reference compounds. The relatively unstable 1-alkene-1-thiols represent a new class of food odorants and are suggested as the key contributors to the characteristic, but quickly vanishing, aroma of freshly ground roasted sesame seeds.

Impact of N-acetylcysteine and sesame oil on lipid metabolism and hypothalamic-pituitary-adrenal axis homeostasis in middle-aged hypercholesterolemic mice

PubMed Central

Korou, Laskarina-Maria; Agrogiannis, George; Koros, Christos; Kitraki, Efthimia; Vlachos, Ioannis S.; Tzanetakou, Irene; Karatzas, Theodore; Pergialiotis, Vasilios; Dimitroulis, Dimitrios; Perrea, Despina N.

2014-01-01

Hyperlipidemia and stress are important factors affecting cardiovascular health in middle-aged individuals. We investigated the effects of N-acetylcysteine (NAC) and sesame oil on the lipidemic status, liver architecture and the hypothalamic-pituitary-adrenal (HPA) axis of middle-aged mice fed a cholesterol-enriched diet. We randomized 36 middle-aged C57bl/6 mice into 6 groups: a control group, a cholesterol/cholic acid diet group, a cholesterol/cholic acid diet group with NAC supplementation, a cholesterol/cholic acid diet enriched with 10% sesame oil and two groups receiving a control diet enriched with NAC or sesame oil. NAC administration prevented the onset of the disturbed lipid profile, exhibiting decreased lipid peroxidation and alkaline phosphatase (ALP) levels, restored nitric oxide bioavailability and reduced hepatic damage, compared to non-supplemented groups. High-cholesterol feeding resulted in increased hypothalamic glucocorticoid receptors (GR) levels, while NAC supplementation prevented this effect. NAC supplementation presented significant antioxidant capacity by means of preventing serum lipid status alterations, hepatic damage, and HPA axis disturbance due to high-cholesterol feeding in middle-aged mice. These findings suggest a beneficial preventive action of plant-derived antioxidants, such as NAC, on lipid metabolism and on the HPA axis. PMID:25348324

Generation of bound states of pulses in a SESAM mode-locked Cr:ZnSe laser

NASA Astrophysics Data System (ADS)

Bu, Xiangbao; Shi, Yuhang; Xu, Jia; Li, Huijuan; Wang, Pu

2018-06-01

We report on the generation of bound states of pulses in a SESAM mode-locked Cr:ZnSe laser around 2415 nm. A thulium-doped double-clad fiber laser at 1908 nm was used as the pump source. Bound states with various pulse separations at different dispersion regimes were obtained. Especially, in the anomalous dispersion regime, vibrating bound state of solitons exhibiting an evolving phase was obtained.

A high-resolution model of the planetary boundary layer - Sensitivity tests and comparisons with SESAME-79 data

NASA Technical Reports Server (NTRS)

Zhang, D.; Anthes, R. A.

1982-01-01

A one-dimensional, planetary boundary layer (PBL) model is presented and verified using April 10, 1979 SESAME data. The model contains two modules to account for two different regimes of turbulent mixing. Separate parameterizations are made for stable and unstable conditions, with a predictive slab model for surface temperature. Atmospheric variables in the surface layer are calculated with a prognostic model, with moisture included in the coupled surface/PBL modeling. Sensitivity tests are performed for factors such as moisture availability, albedo, surface roughness, and thermal capacity, and a 24 hr simulation is summarized for day and night conditions. The comparison with the SESAME data comprises three hour intervals, using a time-dependent geostrophic wind. Close correlations were found with daytime conditions, but not in nighttime thermal structure, while the turbulence was faithfully predicted. Both geostrophic flow and surface characteristics were shown to have significant effects on the model predictions

Purification and fermentation in vitro of sesaminol triglucoside from sesame cake by human intestinal microbiota.

PubMed

Zhu, Xiuling; Zhang, Xin; Sun, Yongkang; Su, Di; Sun, Yi; Hu, Bing; Zeng, Xiaoxiong

2013-02-27

Sesaminol triglucoside (STG), the most abundant lignan glycoside existing in sesame cake/meal, has exhibited various biological activities. However, little information about its in vitro fermentation with intestinal microbiota is available. Therefore, the effect of STG from sesame cake on the fermentation of human fecal microbiota was evaluated. First, high-purity STG was successfully prepared from defatted sesame cake by extraction with 80% ethanol and simple purification procedures of polyamide column chromatography and Toyopearl HW-40S column chromatography. Then the influence of STG on intestinal microbiota was conducted by monitoring bacterial populations and analyzing the concentrations of short-chain fatty acids (SCFA). We found that STG could significantly induce an increase in numbers of Lactobacillus - Enterococcus group and Bifidobacterium in fermentation in vitro with human fecal microbiota, while it did not stimulate the bacterial growth of Eubacterium rectale - Clostridium coccoides group, Clostridium histolyticum group, and Bacteroides - Prevotella group. Furthermore, it was found that concentrations of formic, acetic, propionic, and butyric acids in STG culture increased significantly during the fermentation, and its total SCFA concentration was relatively higher than those of the control and glucose cultures at 6 and 12 h fermentation. Our findings provided further evidence for the importance of human intestinal bacteria in the bioactivity of STG and its metabolites in the maintenance of human health.

First-principles equation-of-state table of beryllium based on density-functional theory calculations

DOE PAGES

Ding, Y. H.; Hu, S. X.

2017-06-06

Beryllium has been considered a superior ablator material for inertial confinement fusion (ICF) target designs. An accurate equation-of-state (EOS) of beryllium under extreme conditions is essential for reliable ICF designs. Based on density-functional theory (DFT) calculations, we have established a wide-range beryllium EOS table of density ρ = 0.001 to 500 g/cm 3 and temperature T = 2000 to 10 8 K. Our first-principle equation-of-state (FPEOS) table is in better agreement with the widely used SESAME EOS table (SESAME 2023) than the average-atom INFERNO and Purgatorio models. For the principal Hugoniot, our FPEOS prediction shows ~10% stiffer than the lastmore » two models in the maximum compression. Although the existing experimental data (only up to 17 Mbar) cannot distinguish these EOS models, we anticipate that high-pressure experiments at the maximum compression region should differentiate our FPEOS from INFERNO and Purgatorio models. Comparisons between FPEOS and SESAME EOS for off-Hugoniot conditions show that the differences in the pressure and internal energy are within ~20%. By implementing the FPEOS table into the 1-D radiation–hydrodynamic code LILAC, we studied in this paper the EOS effects on beryllium-shell–target implosions. Finally, the FPEOS simulation predicts higher neutron yield (~15%) compared to the simulation using the SESAME 2023 EOS table.« less

First-principles equation-of-state table of beryllium based on density-functional theory calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ding, Y. H.; Hu, S. X.

Beryllium has been considered a superior ablator material for inertial confinement fusion (ICF) target designs. An accurate equation-of-state (EOS) of beryllium under extreme conditions is essential for reliable ICF designs. Based on density-functional theory (DFT) calculations, we have established a wide-range beryllium EOS table of density ρ = 0.001 to 500 g/cm 3 and temperature T = 2000 to 10 8 K. Our first-principle equation-of-state (FPEOS) table is in better agreement with the widely used SESAME EOS table (SESAME 2023) than the average-atom INFERNO and Purgatorio models. For the principal Hugoniot, our FPEOS prediction shows ~10% stiffer than the lastmore » two models in the maximum compression. Although the existing experimental data (only up to 17 Mbar) cannot distinguish these EOS models, we anticipate that high-pressure experiments at the maximum compression region should differentiate our FPEOS from INFERNO and Purgatorio models. Comparisons between FPEOS and SESAME EOS for off-Hugoniot conditions show that the differences in the pressure and internal energy are within ~20%. By implementing the FPEOS table into the 1-D radiation–hydrodynamic code LILAC, we studied in this paper the EOS effects on beryllium-shell–target implosions. Finally, the FPEOS simulation predicts higher neutron yield (~15%) compared to the simulation using the SESAME 2023 EOS table.« less

SESAME-A 3rd Generation Synchrotron Light Source for the Middle East

NASA Astrophysics Data System (ADS)

Winick, Herman

2010-02-01

Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research center in construction in Jordan. It will enable world class research by scientists from the region, reversing the brain drain. It will also build bridges between diverse societies, contributing to a culture of peace through international cooperation in science. The centerpiece is a synchrotron light source originating from BESSY I, a gift by Germany. The upgraded machine, a 2.5 GeV 3rd Generation Light Source (133m circumference, 26nm-rad emittance and 12 places for insertion devices), will provide light from infra-red to hard X-rays, offering excellent opportunities to train local scientists and attract those working abroad to return. The SESAME Council meets twice each year and presently has nine Members (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey). Members have responsibility for the project and provide the annual operations budget (1.5M US dollars in 2009, expected to rise to about 5M when operation starts in 2012-13). Jordan provided the site, building, and infrastructure. A staff of 20 is installing the 0.8 GeV BESSY I injection system. The facility will have the capacity to serve 30 or more experiments operating simultaneously. See www.sesame.org.jo )

Evaluation of phosphorus adsorption capacity of sesame straw biochar on aqueous solution: influence of activation methods and pyrolysis temperatures.

PubMed

Park, J H; Ok, Y S; Kim, S H; Cho, J S; Heo, J S; Delaune, R D; Seo, D C

2015-12-01

The phosphorus (P) adsorption characteristic of sesame straw biochar prepared with different activation agents and pyrolysis temperatures was evaluated. Between 0.109 and 0.300 mg L(-1) in the form of inorganic phosphate was released from raw sesame straw biochar in the first 1 h. The release of phosphate was significantly enhanced from 62.6 to 168.2 mg g(-1) as the pyrolysis temperature increased. Therefore, sesame straw biochar cannot be used as an adsorbent for P removal without change in the physicochemical characteristics. To increase the P adsorption of biochar in aqueous solution, various activation agents and pyrolysis temperatures were applied. The amount of P adsorbed from aqueous solution by biochar activated using different activation agents appeared in the order ZnCl2 (9.675 mg g(-1)) > MgO (8.669 mg g(-1)) ⋙ 0.1N-HCl > 0.1N-H2SO4 > K2SO4 ≥ KOH ≥ 0.1N-H3PO4, showing ZnCl2 to be the optimum activation agent. Higher P was adsorbed by the biochar activated using ZnCl2 under different pyrolysis temperatures in the order 600 °C > 500 °C > 400 °C > 300 °C. Finally, the amount of adsorbed P by activated biochar at different ratios of biochar to ZnCl2 appeared in the order 1:3 ≒ 1:1 > 3:1. As a result, the optimum ratio of biochar to ZnCl2 and pyrolysis temperature were found to be 1:1 and 600 °C for P adsorption, respectively. The maximum P adsorption capacity by activated biochar using ZnCl2 (15,460 mg kg(-1)) was higher than that of typical biochar, as determined by the Langmuir adsorption isotherm. Therefore, the ZnCl2 activation of sesame straw biochar was suitable for the preparation of activated biochar for P adsorption.

SESAME: an opportunity for science in the Middle-East

NASA Astrophysics Data System (ADS)

Paolucci, Giorgio

SESAME, the Synchrotron Radiation Laboratory of the Middle East, is becoming reality. As of November 2016, the injector has been commissioned, the storage ring is in an advanced state of installation and it is expected that two beamlines (XAFS/XRF and IR) will start producing scientific results in 2017. The talk will present the status of the facility and will illustrate its scientific objectives. The expected social and cultural impact of the project in the tumultuous Middle East Region will also be highlighted.

Diode-pumped Alexandrite laser with passive SESAM Q-switching and wavelength tunability

NASA Astrophysics Data System (ADS)

Parali, Ufuk; Sheng, Xin; Minassian, Ara; Tawy, Goronwy; Sathian, Juna; Thomas, Gabrielle M.; Damzen, Michael J.

2018-03-01

We report the first experimental demonstration of a wavelength tunable passively Q-switched red-diode-end pumped Alexandrite laser using a semiconductor saturable absorber mirror (SESAM). We present the results of the study of passive SESAM Q-switching and wavelength-tuning in continuous diode-pumped Alexandrite lasers in both linear cavity and X-cavity configurations. In the linear cavity configuration, pulsed operation up to 27 kHz repetition rate in fundamental TEM00 mode was achieved and maximum average power was 41 mW. The shortest pulse generated was 550 ns (FWHM) and the Q-switched wavelength tuning band spanned was between 740 nm and 755 nm. In the X-cavity configuration, a higher average power up to 73 mW, and obtained with higher pulse energy 6 . 5 μJ at 11.2 kHz repetition rate, in fundamental TEM00 mode with excellent spatial quality M2 < 1 . 1. The Q-switched wavelength tuning band spanned was between 775 nm and 781 nm.

Semiconductor saturable absorber mirror passively Q-switched 2.97 μm fluoride fiber laser

NASA Astrophysics Data System (ADS)

Li, Jianfeng; Luo, Hongyu; He, Yulian; Liu, Yong; Luo, Binbin; Sun, Zhongyuan; Zhang, Lin; Turitsyn, Sergei K.

2014-05-01

A diode-cladding-pumped mid-infrared passively Q-switched Ho3+-doped fluoride fiber laser using a reverse designed broad band semiconductor saturable mirror (SESAM) was demonstrated. Nonlinear reflectivity of the SESAM was measured using an in-house Yb3+-doped mode-locked fiber laser at 1062 nm. Stable pulse train was produced at a slope efficient of 12.1% with respect to the launched pump power. Maximum pulse energy of 6.65 μJ with a pulse width of 1.68 μs and signal to noise ratio (SNR) of ~50 dB was achieved at a repetition rate of 47.6 kHz and center wavelength of 2.971 μm. To the best of our knowledge, this is the first 3 μm region SESAM based Q-switched fiber laser with the highest average power and pulse energy, as well as the longest wavelength from mid-infrared passively Q-switched fluoride fiber lasers.

Semiconductor saturable absorber mirror passively Q-switched 2.97 μm fluoride fiber laser

NASA Astrophysics Data System (ADS)

Li, J. F.; Luo, H. Y.; He, Y. L.; Liu, Y.; Zhang, L.; Zhou, K. M.; Rozhin, A. G.; Turistyn, S. K.

2014-06-01

A diode-cladding-pumped mid-infrared passively Q-switched Ho3+-doped fluoride fiber laser using a reverse designed broad band semiconductor saturable mirror (SESAM) was demonstrated. Nonlinear reflectivity of the SESAM was measured using an in-house Yb3+-doped mode-locked fiber laser at 1062 nm. Stable pulse train was produced at a slope efficient of 12.1% with respect to the launched pump power. Maximum pulse energy of 6.65 µJ with a pulse width of 1.68 µs and signal-to-noise ratio (SNR) of ~50 dB was achieved at a repetition rate of 47.6 kHz and center wavelength of 2.971 µm. To the best of our knowledge, this is the first 3 µm region SESAM-based Q-switched fiber laser with the highest average power and pulse energy, as well as the longest wavelength from mid-infrared passively Q-switched fluoride fiber lasers.

Moisture processes accompanying convective activity

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.; Scoggins, J. R.

1982-01-01

A moisture budget analysis was performed on data collected during the AVE 7 (May 2 to 3, 1978) and AVE-SESAME1 (April 10 to 11, 1979) experiments. Local rates-of-change of moisture were compared with average moisture divergence in the same time period. Results were presented as contoured plots in the horizontal and as vertical cross sections. These results were used to develop models of the distribution of moisture processes in the vicinity of convective areas in two layers representing lower and middle tropospheric conditions. Good correspondence was found between the residual term of the moisture budget and actual precipitation.

Penicillium sp. mitigates Fusarium-induced biotic stress in sesame plants.

PubMed

Radhakrishnan, Ramalingam; Pae, Suk-Bok; Shim, Kang-Bo; Baek, In-Youl

2013-07-01

Fusarium-infected sesame plants have significantly higher contents of amino acids (Asp, Thr, Ser, Asn, Glu, Gly, Ala, Val, Met, Ile, Leu, Tyr, Phe, Lys, His, Try, Arg, and Pro), compared with their respective levels in the healthy control. These higher levels of amino acids induced by Fusarium infection were decreased when Penicillium was co-inoculated with Fusarium. Compared with the control, Fusarium-infected plants showed higher contents of palmitic (8%), stearic (8%), oleic (7%), and linolenic acids (4%), and lower contents of oil (4%) and linoleic acid (11%). Co-inoculation with Penicillium mitigated the Fusarium-induced changes in fatty acids. The total chlorophyll content was lower in Fusarium- and Penicillium-infected plants than in the healthy control. The accumulation of carotenoids and γ-amino butyric acid in Fusarium-infected plants was slightly decreased by co-inoculation with Penicillium. Sesamin and sesamolin contents were higher in Penicillium- and Fusarium- infected plants than in the control. To clarify the mechanism of the biocontrol effect of Penicillium against Fusarium by evaluating changes in primary and secondary metabolite contents in sesame plants.

The effect of the arbitrary level assignment of satellite cloud motion wind vectors on wind analyses in the pre-thunderstorm environment

NASA Technical Reports Server (NTRS)

Peslen, C. A.; Koch, S. E.; Uccellini, L. W.

1985-01-01

The impact of satellite-derived cloud motion vectors on SESAME rawinsonde wind fields was studied in two separate cases. The effect of wind and moisture gradients on the arbitrary assignment of the satellite data is assessed to coordinate surfaces in a severe storm environment marked by strong vertical wind shear. Objective analyses of SESAME rawinsonde winds and combined winds are produced and differences between these two analyzed fields are used to make an assessment of coordinate level choice. It is shown that the standard method of arbitrarily assigning wind vectors to a low level coordinate surface yields systematic differences between the rawinsonde and combined wind analyses. Arbitrary assignment of cloud motions to the 0.9 sigma surface produces smaller differences than assignment to the 825 mb pressure surface. Systematic differences occur near moisture discontinuities and in regions of horizontal and vertical wind shears. The differences between the combined and SESAME wind fields are made smallest by vertically interpolating cloud motions to either a pressure or sigma surface.

/III-V semiconductor broadband distributed Bragg reflectors for long-wavelength VCSEL and SESAM devices

NASA Astrophysics Data System (ADS)

Koeninger, Anna; Boehm, Gerhard; Meyer, Ralf; Amann, Markus-Christian

2014-12-01

Semiconductor devices such as vertical-cavity surface-emitting lasers (VCSELs) or semiconductor-saturable absorber mirrors (SESAMs) require high-reflection mirrors. Moreover, in VCSELs, it is beneficial to have a crystalline mirror, which is as thin as possible in order to ensure a high thermal conductivity for efficient heat-sinking of the laser. On the other hand, the wavelength tuning range of a SESAM is limited by the reflection bandwidth of its distributed Bragg reflector (DBR). Thus, broadband mirrors are preferable here. This paper reports a three-pair DBR grown by molecular beam epitaxy (MBE) using BaCaF2 and GaAs on a GaAs (100) substrate. Due to the high ratio in refractive indices of GaAs and the group-IIa-fluorides, high-reflectivity mirrors and wide bandwidths can be obtained with low total thicknesses. We also investigated growth and stability of the material BaCaF2, as well as its thermal conductivity both as single layer and Bragg reflector. Observed peeling of the layers could be avoided by implementing a fluorine treatment previous to the BaCaF2 growth.

Bunch of restless vector solitons in a fiber laser with SESAM.

PubMed

Zhao, L M; Tang, D Y; Zhang, H; Wu, X

2009-05-11

We report on the experimental observation of a novel form of vector soliton interaction in a fiber laser mode-locked with SESAM. Several vector solitons bunch in the cavity and move as a unit with the cavity repetition rate. However, inside the bunch the vector solitons make repeatedly contractive and repulsive motions, resembling the contraction and extension of a spring. The number of vector solitons in the bunch is controllable by changing the pump power. In addition, polarization rotation locking and period doubling bifurcation of the vector soliton bunch are also experimentally observed.

Limited Range Sesame EOS for Ta

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greeff, Carl William; Crockett, Scott; Rudin, Sven Peter

2017-03-30

A new Sesame EOS table for Ta has been released for testing. It is a limited range table covering T ≤ 26, 000 K and ρ ≤ 37.53 g/cc. The EOS is based on earlier analysis using DFT phonon calculations to infer the cold pressure from the Hugoniot. The cold curve has been extended into compression using new DFT calculations. The present EOS covers expansion into the gas phase. It is a multi-phase EOS with distinct liquid and solid phases. A cold shear modulus table (431) is included. This is based on an analytic interpolation of DFT calculations.

Consistent characterization of semiconductor saturable absorber mirrors with single-pulse and pump-probe spectroscopy.

PubMed

Fleischhaker, R; Krauss, N; Schättiger, F; Dekorsy, T

2013-03-25

We study the comparability of the two most important measurement methods used for the characterization of semiconductor saturable absorber mirrors (SESAMs). For both methods, single-pulse spectroscopy (SPS) and pump-probe spectroscopy (PPS), we analyze in detail the time-dependent saturation dynamics inside a SESAM. Based on this analysis, we find that fluence-dependent PPS at complete spatial overlap and zero time delay is equivalent to SPS. We confirm our findings experimentally by comparing data from SPS and PPS of two samples. We show how to interpret this data consistently and we give explanations for possible deviations.

Response of the Cutworm Spodoptera litura to Sesame Leaves or Crude Extracts in Diet

PubMed Central

Ofosuhene Sintim, Henry; Tashiro, Toru; Motoyama, Naoki

2009-01-01

The effects of extracts of sesame, Sesamum indicum L. (Liamiales: Pedaliaceae), and whole leaves of some selected cultivars of sesame were tested using a natural host Spodoptera litura (F.) (Lepidoptera: Noctuidae). Indices taken using the immature stages include; diet utilization, growth and development and induction of detoxification enzymes. The results indicate that S. litura generally selects its food amongst cultivars within 6 hours after food presentation. Growth and development of the insect is controlled also by plant acceptability and quality. Although all the cultivars tested significantly limit insect growth and development the variety 56S-radiatum did not allow a complete life cycle as pupation from first instar stage was 0%. Generally the crucial period for immature S. litura was the larval period, especially the first two instars where the weight of an insect fed on an experimental diet was three times lower than that of a control diet. The larval developmental period was greater than 40 days as compared to 17 days for insects fed a control diet. S. litura also had lowered efficiency in utilizing ingested food, from a low of 13% in a sesame cultivar to 45% in the control diet. The key detoxification enzyme was a glutathione s-transferase that was confirmed by a 6-fold increase between S. litura fed a plant cultivar vs. a control diet towards the substrate 1,2-dichloro-4-nitrobenzene. First and second instars of S. litura have a relatively reduced detoxification of enzymes in response to plant cultivar diets leading to low survival. A 3% v/w crude extract of the cultivars increased enzyme induction towards all the tested substrates. PMID:20050772

Production of BCG alginate-PLL microcapsules by emulsification/internal gelation.

PubMed

Esquisabel, A; Hernández, R M; Igartua, M; Gascón, A R; Calvo, B; Pedraz, J L

1997-01-01

A biocompatible emulsification method for microencapsulation of live cells and enzymes within a calcium alginate matrix applied to Bacillus Calmette-Guérin (BCG) has been developed. Small-diameter alginate beads (microcapsules) were formed via internal gelation of an alginate solution emulsified within vegetable oil. Five different oils (sesame, sweet almond, perhydrosqualene, camomile and jojoba) were used. The rheological analysis of the oils showed a Newtonian behaviour, with viscosities = 30.0, 37.7, 51.2, 59.3 and 67.1 mPa.s for perhydrosqualene, jojoba, camomile, sesame and sweet almond oil respectively. The particle size of the microcapsules obtained ranged from 30.3 microns for the microcapsules prepared with sweet almond oil to 57.0 microns for those made with perhydrosqualene. The mean particle diameter obtained was found to be dependent on the viscosity of the oil employed, according to the equation: phi (micron) = 76.6-0.628 eta (mPa.s) (r2 = 0.943). The encapsulated BCG was identified by the Difco TB stain set K, followed by observation under optical microscopy. Freeze-drying of the microcapsules was carried out to ensure their stability during storage. Two batches of microcapsules (those prepared with sesame and jojoba oil) and four types of cryoprotectors (glucose, trehalose, mannitol and sorbitol), at three concentration levels (5, 10 and 20% w/v) were studied. The parameters evaluated were particle size, physical appearance, reconstitution of lyophilizates and microscopical evaluation. For both batches of microcapsules the best results were obtained with trehalose 5%, showing particle sizes of 42.1 microns in the case of the microcapsules prepared with sesame oil, and of 45.3 microns for those prepared with jojoba.

Systemic treatment with n-6 polyunsaturated fatty acids attenuates EL4 thymoma growth and metastasis through enhancing specific and non-specific anti-tumor cytolytic activities and production of TH1 cytokines.

PubMed

Salem, Mohamed Labib

2005-06-01

Recently, there has been a great interest in the effects of different types of n-6 polyunsaturated acids (n-6 PUFAs) upon the immune system and cancer development. However, the effects of n-6 PUFAs are still controversial and as yet undefined. The present study aimed to investigate the anti-tumor effects of n-6 PUFAs against EL4 thymoma and the associated immune mechanisms. To this, sesame oil, a vegetable oil enriched with n-6 PUFAs, or free linoleic acid (LA) were administered intraperitoneally into C57BL/6 mice before and after challenge with EL4 lymphoma cells. Treatment with either sesame oil or LA attenuated the growth and metastasis of EL4 lymphoma. The anti-tumor effect of LA was superior to that of sesame oil, and associated with an increase in the survival rate of the tumor-bearing mice. In addition, both sesame oil and LA showed dose-dependent anti-lymphoma growth in vitro. Treatment with LA generated significant increases in the anti-lymphoma cytolytic and cytostatic activities of T cells and macrophages, respectively, and enhanced production of IL-2 and IFN-gamma while decreased production of IL-4, IL-6 and IL-10. In summation, the results suggest that n-6 PUFAs, represented by LA, can attenuate EL4 lymphoma growth and metastasis through enhancing the specific and non-specific anti-tumor cytolytic activities and production of TH1 cytokines. These findings might be of great importance for a proper design of systemic nourishment with PUFAs emulsions for cancer patients.

The light of SESAME: A dream becomes reality

NASA Astrophysics Data System (ADS)

Schopper, H.

2017-04-01

The foundation of the international SESAME synchrotron laboratory in Jordan is described including political, technical, scientific and financial aspects. Following the model of CERN, its objective is not only to promote science but also bring people together from countries with different traditions, religions and mentalities. To create an international organisation in the Middle East and North Africa (MENA) region required sometimes quite unconventional procedures not disclosed in any official document. Because of the exceptional circumstances, a more detailed description of its history may be of interest. Although its success was doubted by many at its start, the facility will start operation in spring 2017.

A 12.1-W SESAM mode-locked Yb:YAG thin disk laser

NASA Astrophysics Data System (ADS)

Yingnan, Peng; Zhaohua, Wang; Dehua, Li; Jiangfeng, Zhu; Zhiyi, Wei

2016-05-01

Pumped by a 940 nm fiber-coupled diode laser, a passively mode-locked Yb:YAG thin disk oscillator was demonstrated with a semiconductor saturable absorber mirror (SESAM). 12.1 W mode-locked pulses were obtained with pulse duration of 698 fs at the repetition rate of 57.43 MHz. Measurement showed that the beam quality was close to the diffraction limit. Project supported by the National Key Basic Research Program of China (Grant No. 2013CB922402), the National Major Instrument Program of China (Grant No. 2012YQ120047), and the National Natural Science Foundation of China (Grant No. 61210017).

An Overview of Chemical Profiles, Antioxidant and Antimicrobial Activities of Commercial Vegetable Edible Oils Marketed in Japan

PubMed Central

Gangqiang, Gu; Quy, Tran Ngoc; Khanh, Tran Dang

2018-01-01

This study analyzed chemical components and investigated the antioxidant and antimicrobial activities of fourteen vegetable edible oils marketed in Japan. High-performance liquid chromatography (HPLC) was used to identify and quantify principal phenolic acids and flavonoids. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay, sunflower, safflower, canola, soybean, Inca inchi, sesame, and rice bran showed markedly greater activity, whilst the percentage of lipid peroxidation inhibition (LPI%) in sunflower, canola, cotton, grape, flax, perilla, Inca inchi, perillartine, and rice bran were significantly higher than other oils. Maximum total phenol content (TPC) was recorded in flax, followed by perillartine, rice bran, and perilla, whereas total flavonoid content (TFC) was the greatest in Inca inchi and sesame. Benzoic acid was the most common constituent, followed by vanillic acid, p-hydroxybenzoic acid, ferulic acid, and p-coumaric acid. On the other hand, luteolin was the most abundant flavonoid, followed by esculetin, myricetin, isoquercetin, and kaempferol, while fisetin was detected only in sunflower. In general, all of the edible oils showed antimicrobial activity, but the growth inhibition of Staphylococcus aureus and Escherichia coli of cotton, grape, chia, sesame, and rice bran were greater than other oils. PMID:29439420

A new high-frequency Agrobacterium-mediated transformation technique for Sesamum indicum L. using de-embryonated cotyledon as explant.

PubMed

Chowdhury, Supriyo; Basu, Arpita; Kundu, Surekha

2014-09-01

In spite of the economic importance of sesame (Sesamum indicum L.) and the recent availability of its genome sequence, a high-frequency transformation protocol is still not available. The only two existing Agrobacterium-mediated transformation protocols that are available have poor transformation efficiencies of less than 2%. In the present study, we report a high-frequency, simple, and reproducible transformation protocol for sesame. Transformation was done using de-embryonated cotyledons via somatic embryogenic stages. All the critical parameters of transformation, like incubation period of explants in pre-regeneration medium prior to infection by Agrobacterium tumefaciens, cocultivation period, concentrations of acetosyringone in cocultivation medium, kanamycin concentration, and concentration of plant hormones, including 6-benzylaminopurine, have been optimized. This protocol is superior to the two existing protocols in its high regeneration and transformation efficiencies. The transformed sesame lines have been tested by PCR, RT-PCR for neomycin phosphotransferase II gene expression, and β-glucuronidase (GUS) assay. The regeneration frequency and transformation efficiency are 57.33 and 42.66%, respectively. T0 and T1 generation transgenic plants were analyzed, and several T1 plants homozygous for the transgenes were obtained.

Studies of porous anodic alumina using spin echo scattering angle measurement

NASA Astrophysics Data System (ADS)

Stonaha, Paul

The properties of a neutron make it a useful tool for use in scattering experiments. We have developed a method, dubbed SESAME, in which specially designed magnetic fields encode the scattering signal of a neutron beam into the beam's average Larmor phase. A geometry is presented that delivers the correct Larmor phase (to first order), and it is shown that reasonable variations of the geometry do not significantly affect the net Larmor phase. The solenoids are designed using an analytic approximation. Comparison of this approximate function with finite element calculations and Hall probe measurements confirm its validity, allowing for fast computation of the magnetic fields. The coils were built and tested in-house on the NBL-4 instrument, a polarized neutron reflectometer whose construction is another major portion of this work. Neutron scattering experiments using the solenoids are presented, and the scattering signal from porous anodic alumina is investigated in detail. A model using the Born Approximation is developed and compared against the scattering measurements. Using the model, we define the necessary degree of alignment of such samples in a SESAME measurement, and we show how the signal retrieved using SESAME is sensitive to range of detectable momentum transfer.

SESAME -- A light source for the Middle East

NASA Astrophysics Data System (ADS)

Winick, Herman

2012-02-01

Developed under UNESCO and modelled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research centre in construction in Jordan, enabling world-class research while promoting peace through scientific cooperation. Its centerpiece, a new 2.5 GeV 3rd Generation Electron Storage Ring (133m circumference, 26nm-rad emittance, 12 places for insertion devices), will provide intense light from infra-red to hard X-rays. The Council (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey), provides the annual budget. Concrete shielding is complete, and a staff of 21 is installing the refurbished 0.8 GeV BESS Y I injector system, a gift from Germany. The facility can serve 25 simultaneous experiments. Beamline equipment has been provided by Daresbury (UK), the Helmholtz Assoc. (Germany), the Swiss Light Source, LURE (France), the Univ. of Liverpool, Elettra (Italy) and US labs. Jordan has contributed 3.3M, in addition to a building and land. The EU has contributed 4.8M. Commitments confirmed by Members look set to provide most of 35M needed to complete construction of the ring and 3 beamlines. A training program has been underway since 2000. See www.sesame.org.jo

SESAME -- A third generation synchrotron light source for the Middle East

NASA Astrophysics Data System (ADS)

Winick, Herman

2012-03-01

Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research centre in construction in Jordan, enabling world-class research while promoting peace through scientific cooperation. Its centerpiece, a new 2.5 GeV 3rd Generation Electron Storage Ring (133m circumference, 26nm-rad emittance, 12 places for insertion devices), will provide intense light from infra-red to hard X-rays. Members of the Council (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority,Turkey) provide the operations budget. Voluntary contributions by several Council Members that could amount to over 20 million over 5 years are now being finalized. This, plus funds from other sources, will enable acquisition of the technical components of the new ring and the upgrading of beamline equipment donated by several European and US labs. All concrete shielding is complete. The 0.8 GeV BESSY I injector system, a gift from Germany, is now being installed. A training program has been underway since 2000. SESAME is on track to start operation with four day-one beam lines in 2015.

The effects of sesame oil on the prevention of amiodarone-induced phlebitis.

PubMed

Bagheri-Nesami, Masoumeh; Shorofi, Seyed Afshin; Hashemi-Karoie, Seyedeh Zahra; Khalilian, Alireza

2015-01-01

Phlebitis is the most common complication associated with peripheral intravenous infusion of amiodarone. The purpose of this study is to determine the effects of sesame oil on the prevention of amiodarone-induced phlebitis. This is a double-blind randomized controlled trial. Thirty-six patients hospitalized in a coronary care unit were randomly allocated into two groups using a convenience sampling method. Following peripheral intravenous cannulation, five drops of pure sesame oil were applied to the skin within a 10 cm radius of the infusion site prior to the administration of amiodarone in the intervention group. Sesame oil was rubbed on the skin at the infusion site every 6 h in the 24-h period of amiodarone infusion. In the control group, liquid paraffin, used as a placebo, was rubbed on the skin at the infusion site of amiodarone. Both groups were monitored for the development of phlebitis and its degree within the 24-h period of amiodarone infusion as well as 6 h after its administration. The incidence of phlebitis was confirmed and recorded by an assessor who was blind to the two groups. Data were analyzed using Statistical Package for Social Science (SPSS) version 18, and descriptive and inferential statistics such as Chi-square test, Kaplan-Meier, Hazard ratio, independent t-test, and Fisher's exact test. There was a statistically significant difference between the two groups in their catheter survival after 30 h and 10 min (P < 0.001). Over 60% of the patients (61.1%) in the intervention group did not show any sign of phlebitis, while 16.7% and 22.2% of the patients manifested signs of grade 2 and 3 phlebitis, respectively. In the control group, 22.2% of the patients showed no signs of phlebitis, while 5.6%, 27.8%, and 44.4% of the patients exhibited signs of grade 2, 3, and 4 phlebitis, respectively. The statistical analysis showed significant differences in the degree of phlebitis (P = 0.006) and the onset of phlebitis development (P < 0.001) between the two groups. It is recommended to apply sesame oil topically to the infusion site of amiodarone so as to reduce the rate of the development of amiodarone-related phlebitis.

The effects of sesame oil on the prevention of amiodarone-induced phlebitis

PubMed Central

Bagheri-Nesami, Masoumeh; Shorofi, Seyed Afshin; Hashemi-Karoie, Seyedeh Zahra; Khalilian, Alireza

2015-01-01

Background: Phlebitis is the most common complication associated with peripheral intravenous infusion of amiodarone. The purpose of this study is to determine the effects of sesame oil on the prevention of amiodarone-induced phlebitis. Materials and Methods: This is a double-blind randomized controlled trial. Thirty-six patients hospitalized in a coronary care unit were randomly allocated into two groups using a convenience sampling method. Following peripheral intravenous cannulation, five drops of pure sesame oil were applied to the skin within a 10 cm radius of the infusion site prior to the administration of amiodarone in the intervention group. Sesame oil was rubbed on the skin at the infusion site every 6 h in the 24-h period of amiodarone infusion. In the control group, liquid paraffin, used as a placebo, was rubbed on the skin at the infusion site of amiodarone. Both groups were monitored for the development of phlebitis and its degree within the 24-h period of amiodarone infusion as well as 6 h after its administration. The incidence of phlebitis was confirmed and recorded by an assessor who was blind to the two groups. Data were analyzed using Statistical Package for Social Science (SPSS) version 18, and descriptive and inferential statistics such as Chi-square test, Kaplan–Meier, Hazard ratio, independent t-test, and Fisher's exact test. Results: There was a statistically significant difference between the two groups in their catheter survival after 30 h and 10 min (P < 0.001). Over 60% of the patients (61.1%) in the intervention group did not show any sign of phlebitis, while 16.7% and 22.2% of the patients manifested signs of grade 2 and 3 phlebitis, respectively. In the control group, 22.2% of the patients showed no signs of phlebitis, while 5.6%, 27.8%, and 44.4% of the patients exhibited signs of grade 2, 3, and 4 phlebitis, respectively. The statistical analysis showed significant differences in the degree of phlebitis (P = 0.006) and the onset of phlebitis development (P < 0.001) between the two groups. Conclusions: It is recommended to apply sesame oil topically to the infusion site of amiodarone so as to reduce the rate of the development of amiodarone-related phlebitis. PMID:26120338

Electrical properties of the first meters of 67P/Churyumov-Gerasimenko's nucleus as constrained by PP-SESAME/Philae/Rosetta

NASA Astrophysics Data System (ADS)

Le Gall, Alice; Lethuillier, Anthony; Hamelin, Michel; Schimdt, Walter; Grard, Rejean; Ciarletti, Valérie; Seidensticker, Klaus; Caujolle-Bert, Sylvain; Fischer, Hans-Herbert

2016-04-01

On November 12, 2014, the Philae module landed on the surface of the nucleus of 67P/Churyumov-Gerasimenko. Among the instruments on-board Philae, the Permittivity Probe experiment (hereafter PP-SESAME), which is part of the SESAME (Surface Electric Sounding and Acoustic Monitoring Experiment) package, operated both during descent and on the surface. The primary scientific objective of this experiment is to measure the low frequency (10 Hz-10 kHz) complex permittivity i.e., the dielectric constant and electrical conductivity, of the first meters of the cometary nucleus. Doing so, it aims at providing insights into the composition of the mantle and in particular into the water content and porosity of the first meters below the surface. In this paper, we will present the data acquired at the final landing site of Philae known as Abydos and the approach we have developed to analyze them. We emphasize that, because the configuration of operation of PP-SESAME was far from nominal, we had to adapt our analysis method in order to account for all available constraints on Philae attitude and environment at Abydos. We also had to do without the in-flight calibration performed during the descent phase but unfortunately perturbed by the concurrent operations of the bistatic radar CONSERT. We find that the first meters of the nucleus at Abydos are made of a likely pure dielectric material (i.e., with a null conductivity) which dielectric constant is larger than 2.3. This lower bound of the dielectric constant is significantly higher than the value of 1.27 inferred from the propagation time of the CONSERT signals that propagated through the smaller lobe of the comet in the vicinity of Abydos reaching depths of a few hundreds of meters. Thus, while PP-SESAME measurements put no constraint on the dust-to-ice ratio, they strongly suggest that the first meters of the nucleus are significantly more compacted (with a porosity below 50%) than its interior as sensed by CONSERT (found to have a porosity in of 75 to 85%, consistent with the low density of the nucleus). In light of other Philae and Rosetta observations, we will discuss the implications of these findings in terms of formation and evolution of cometary mantles.

Chemical, Rheological and Nutritional Characteristics of Sesame and Olive Oils Blended with Linseed Oil.

PubMed

Hashempour-Baltork, Fataneh; Torbati, Mohammadali; Azadmard-Damirchi, Sodeif; Peter Savage, Geoffrey

2018-03-01

Purpose: Nutritional quality and oxidation stability are two main factors in the evaluation of edible oils. Oils in their pure form do not have an ideal fatty acid composition or suitable oxidative stability during processing or storage. Methods: This study was designed to evaluate the chemical, nutritional and rheological properties of oil mixtures in three ratios of olive: sesame: linseed, 65:30:5; 60:30:10 and 55:30:15. Acidity value, peroxide value, rancimat test, fatty acid profile, nutritional indexes and rheological properties of the oil blends were determined. The nutritional quality was determined by indexes, including the atherogenic and thrombogenic indexs; the ratios of hypocholesterolemic: hypercholesterolemic; poly unsaturated fatty acid: saturated fatty acid and the ω 6 :ω 3 . Results: The results indicated that blending of other vegetable oils with linseed oil could balance ω 6 :ω 3 . Results showed that formulated oils had a good balance of oxidation stability and nutritional properties as well. Rheological data showed that these oil blends followed Newtonian behavior at 4°C and 25°C. Conclusion: According to the results, addition of linseed oil to vegetable oils containing high levels of bioactive compounds was a simple and economic practice to obtain a functional oil with good nutritional and stability properties.

Conference Proceedings from the Annual Carnegie Cognition Symposium (10th) Held at Vail, Colorado on June 2-8, 1974: Cognition and Instruction

DTIC Science & Technology

1976-05-15

the analysis tells us about the data . Analysis of Process Independence Univariate analyses of variance were carried out on the two measures for...Atkinson’s data on third-level optimization is extremely interesting. In a cu.mt controversy about ways to increase equality of educational oPP^tumty Sesame...University Effective Data : 1 May, 1973 Expiration Data : 31 Oct., 1974 Amount of Contract: $30,699 Principal Inveatlgator: Dr. David Klahr («12) 621

Mesoscale aspects of jet streak coupling and implications for the short term forecasting of severe convective storms. [severe environmental storms and mesoscale experiment (SESAME)

NASA Technical Reports Server (NTRS)

Uccellini, L. W.; Kocin, P. J.

1981-01-01

An analysis of a tornado outbreak in Wichita Falls, Texas was analyzed. The coupling of upper and lower tropospheric jet streaks, leading to severe storm outbreaks is illustrated. The high resolution SESAME data sets indicate that mass and momentum adjustments which couple upper and lower tropospheric jets occur within a 3 to 6 hr time frame over a 100 to 500 km domain, and establish the role of isallobaric forcing in the storm development. It is suggested that the output rate of data from the existing 12 hr network be increased to provide better temporal resolution of wind, mass and moisture data.

Passively mode-locked pulse generation in a c-cut Nd:LuVO4 laser at 1086 nm with a semiconductor saturable-absorber mirror

NASA Astrophysics Data System (ADS)

Lin, Ja-Hon; Yang, Pao-Keng; Lin, Wei-Cheng

2012-04-01

We demonstrate a diode-pumped passively mode-locked (ML) c-cut Nd:LuVO4 laser with central wavelength at 1086 nm by shifting the reflectance band of the SESAM into a longer wavelength to result in larger loss around 1068 nm. At 15 W absorbed pump power, the highest output power of the ML pulse was about 2.6 W that corresponded to the 17.3% optical-to-optical conversion efficiency and the slope efficiency of laser was about 22.9%. Using our ML laser as the light source, we have also successfully measured the saturation fluence of the SESAM at 1086 nm.

Properties of macerated herbal oil

PubMed Central

Kantawong, Fahsai; Singhatong, Supawatchara; Srilamay, Aomjai; Boonyuen, Kantarose; Mooti, Niroot; Wanachantararak, Phenphichar; Kuboki, Thasaneeya

2017-01-01

Introduction: The addition of herbs into hot sesame oil could increase the oil-pulling efficiency of sesame oil. The aim of present study was to modify the proportion of herbs and sesame oil with the addition of other ingredients including menthol, camphor, and borneol and improve the medicinal properties and the scent of the oil. Methods: Macerated herbal oil was prepared by heat extraction of five species of herbs (Zingiber cassumunar, Zingiber zerumbet, Plantago major Linn, Citrus hystrix, and Amomum biflorum) with hot sesame oil. The study was performed to evaluate the anti-oxidant, anti-inflammatory, and anti-bacterial properties of this macerated herbal oil. Results: Macerated herbal oil was evaluated for antioxidant activity using DPPH and ABTS assays. It was shown that at dilution 1:2 in DMSO, the macerated herbal oil had DPPH and ABTS radical scavenging activities equal to 63% and 22%, respectively. Macerated herbal oil dilution 1:8 in DMSO demonstrated ferric reducing capacity equivalent to ascorbic acid (0.208 µM) and had reducing power equivalent to butylated hydroxytoluene (BHT) 7.41 µg/mL. MTT assay was performed using immortalized human mesenchymal stem cells (HMSCs) as a cell culture model. The result indicated that the cytotoxic concentration of the macerated herbal oil was ≥ 2.5 µL/mL in complete DMEM. Anti-inflammatory effects were evaluated using the nitrite assay and RT-PCR. It was found that the macerated herbal oil could inhibit nitrite accumulation in culture media. Change in the expression of COX-2, Nrf2, and NF-kB in RT-PCR confirmed the anti-inflammatory activity of the macerated herbal oil. Conclusion: It could be concluded that the macerated herbal oil could inhibit nitrite accumulation in culture media, which might be the inhibitory effect of the macerated herbal oil on COX-2 or Nrf2, the downstream modulator of the COX-2 pathway. Further intensive studies are needed for the optimization before bringing this macerated herbal oil into clinical application. PMID:28546949

The Impact of the SESAME Project on Science and Society in the Middle East

NASA Astrophysics Data System (ADS)

Winick, Herman

2008-04-01

SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is a UNESCO-sponsored project that is constructing an international research laboratory, closely modeled on CERN, in Jordan (www.sesame.org.jo). Ten Members of the governing Council (Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Jordan, Pakistan, Palestinian Authority, and Turkey) have responsibility for the project, led by Herwig Schopper, Council President since 1999. In late 2008 Chris Llewellyn-Smith will become Council President. SESAME was initiated by a gift from Germany of the decommissioned BESSY I facility. The BESSY I 0.8 GeV injector is now being installed in the recently completed building, funded by Jordan, as components are procured for a new 133 m circumference, 2.5 GeV third-generation storage ring with 12 locations for insertion devices. Beam line equipment has been provided by laboratories in France, UK, and US. Support also comes from EU, IAEA, ICTP, Japan Society for the Promotion of Science, the US Department of Energy and State Department, and laboratories around the world. The broad scientific program includes biomedical, environmental, and archaeological programs particularly relevant to the Middle East. Five scientific workshops and six annual Users' meetings have brought together several hundred scientists from the region, along with researchers from around the world. Training programs have enabled about 100 scientists from the region to work at synchrotron radiation laboratories. These activities have already had significant impact on science and society in the Middle East, for example leading to collaborations between scientists from countries that are not particularly friendly with each other, and to national planning emphasizing synchrotron radiation research. When research starts in 2011 this impact will grow as graduate students are trained in the region in many scientific disciplines, and scientists working abroad are attracted to return.

Geometrical layout and optics modelling of the surface science beamline station at the SESAME synchrotron radiation facility.

PubMed

Salah, Wa'el; Sanchez del Rio, Manuel

2011-05-01

The layout and the optical performance of the SGM branch of the D09 bending-magnet beamline, under construction at SESAME, are presented. The beamline is based on the Dragon-type design and delivers photons over the spectral range 15-250 eV. One fixed entrance slit and a movable exit slit are used. The performance of the beamline has been characterized by calculating the mirror reflectivities and the grating efficiencies. The flux and resolution were calculated by ray-tracing using SHADOW. The grating diffraction efficiencies were calculated using the GRADIF code. The results and the overall shapes of the predicted curves are in reasonable agreement with those obtained using an analytical formula.

Compact passively Q-switched single-frequency Er3+/Yb3+ codoped phosphate fiber laser

NASA Astrophysics Data System (ADS)

Zhang, Yuanfei; Wang, Simin; Lin, Wei; Mo, Shupei; Zhao, Qilai; Yang, Changsheng; Feng, Zhouming; Deng, Huaqiu; Peng, Mingying; Yang, Zhongmin; Xu, Shanhui

2017-05-01

We present a compact passively Q-switched single-frequency fiber laser based on a 12-mm-long laboratory-built highly Er3+/Yb3+ codoped phosphate fiber (EYDPF) and a semiconductor saturable absorber mirror (SESAM). An effective cavity length of less than 20 mm ensures the stable single-frequency operation of the Q-switched fiber laser. By employing a SESAM for Q-switching, a single-pulse energy of more than 34.4 nJ is realized with the narrowest pulse duration of 95 ns, and the repetition rate of the Q-switched fiber laser reaches over 600 kHz. In addition, the optical signal-to-noise ratio of the output laser is as high as 68.0 dB.

Survey Email Scheduling and Monitoring in eRCTs (SESAMe): A Digital Tool to Improve Data Collection in Randomized Controlled Clinical Trials.

PubMed

Skonnord, Trygve; Steen, Finn; Skjeie, Holgeir; Fetveit, Arne; Brekke, Mette; Klovning, Atle

2016-11-22

Electronic questionnaires can ease data collection in randomized controlled trials (RCTs) in clinical practice. We found no existing software that could automate the sending of emails to participants enrolled into an RCT at different study participant inclusion time points. Our aim was to develop suitable software to facilitate data collection in an ongoing multicenter RCT of low back pain (the Acuback study). For the Acuback study, we determined that we would need to send a total of 5130 emails to 270 patients recruited at different centers and at 19 different time points. The first version of the software was tested in a pilot study in November 2013 but was unable to deliver multiuser or Web-based access. We resolved these shortcomings in the next version, which we tested on the Web in February 2014. Our new version was able to schedule and send the required emails in the full-scale Acuback trial that started in March 2014. The system architecture evolved through an iterative, inductive process between the project study leader and the software programmer. The program was tested and updated when errors occurred. To evaluate the development of the software, we used a logbook, a research assistant dialogue, and Acuback trial participant queries. We have developed a Web-based app, Survey Email Scheduling and Monitoring in eRCTs (SESAMe), that monitors responses in electronic surveys and sends reminders by emails or text messages (short message service, SMS) to participants. The overall response rate for the 19 surveys in the Acuback study increased from 76.4% (655/857) before we introduced reminders to 93.11% (1149/1234) after the new function (P<.001). Further development will aim at securing encryption and data storage. The SESAMe software facilitates consecutive patient data collection in RCTs and can be used to increase response rates and quality of research, both in general practice and in other clinical trial settings. ©Trygve Skonnord, Finn Steen, Holgeir Skjeie, Arne Fetveit, Mette Brekke, Atle Klovning. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 22.11.2016.

Upgrades to the Polarized Neutron Reflectometer Asterix at LANSCE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pynn, Roger

2015-03-16

We have upgraded the polarized neutron reflectometer, Asterix, at the Lujan Neutron Scattering Center at Los Alamos for the benefit of the research communities that study magnetic and complex-fluid films, both of which play important roles in support of the DOE’s energy mission. The upgrades to the instrument include: • A secondary spectrometer that was integrated with a Huber sample goniometer purchased with other funds just prior to the start of our project. The secondary spectrometer provides a flexible length for the scattered flight path, includes a mechanism to select among 3 alternative polarization analyzers as well as a supportmore » for new neutron detectors. Also included is an optic rail for reproducible positioning of components for Spin Echo Scattering Angle Measurement (SESAME). The entire secondary spectrometer is now non-magnetic, as required for neutron Larmor labeling. • A broad-band neutron polarizer for the incident neutron beam based on the V geometry. • A wide-angle neutron polarization analyzer • A 2d position-sensitive neutron detector • Electromagnetic coils (Wollaston prisms) for SESAME plus the associated power supplies, cooling, safety systems and integration into the data acquisition system. The upgrades allowed a nearly effortless transition between configurations required to serve the polarized neutron reflectometry community, users of the 11 T cryomagnet and users of SESAME.« less

Identification and evaluation of anti-inflammatory properties of aqueous components extracted from sesame (Sesamum indicum) oil.

PubMed

Deme, Pragney; Narasimhulu, Chandrakala Aluganti; Parthasarathy, Sampath

2018-06-15

We previously reported that sesame oil (SO) has anti-inflammatory, anti-atherosclerotic and lipid lowering properties in vivo. Our recent studies have shown that, an aqueous extract of sesame oil (SOAE) has also anti-inflammatory and anti-atherosclerotic properties but with no lipid lowering effects. The extent of reduction in atherosclerosis led us to identify components of SOAE and evaluate their anti-inflammatory properties in vitro. Liquid chromatography mass spectrometric method was used to detect and identify components of SOAE. Methoxyphenol derivatives, short and long chain carboxylic acids, dicarboxylic acids, hydroxy and oxo- carboxylic acids were detected. To our surprise, sesamol and its derivatives (lignans), were not present in the SOAE. Among the identified, a combination of methoxy phenol compounds were selected and tested their ability to reduce LPS induced inflammatory gene expression. Monocyte derived macrophages/RAW 264.7 macrophages were pre-treated with these compounds for 2 h, followed by LPS stimulation for 24 h and pro-inflammatory gene expressions were analyzed. These methoxyphenol derivatives showed potent anti-inflammatory properties. In conclusion, the anti-inflammatory molecules associated with SO may contribute the anti-inflammatory and anti-atherosclerotic properties. Also, our results shed light for the development of SOAE based non-pharmacological therapeutics, nutritional supplements and health products for various inflammatory diseases in the future. Copyright © 2018 Elsevier B.V. All rights reserved.

Thermal Degradation of Complexes Derived from Cu (II) Groundnut (Arachis hypogaea) and Sesame (Sesamum indicum) Soaps

NASA Astrophysics Data System (ADS)

Joram, Anju; Sharma, Rashmi; Sharma, Arun kumar

2018-05-01

The complexes have been synthesized from Cu (II) soaps of groundnut (Arachis hypogaea) and sesame (Sesamum indicum) oils, with ligand containing nitrogen and sulfur atoms like 2-amino-6-methyl benzothiazole. The complexes were greenish brown in color. In order to study TGA, first characterized them by elemental analysis, and spectroscopic technique such as IR, NMR and ESR. From the analytical data, the stoichiometry's of the complexes have been observed to be 1:1 (metal:ligand). These complexes have been thermally analyzed using TGA techniques to determine their energy of activation. These complexes show three step thermal degradation corresponding to fatty acid components of the edible oils and each complex has three decomposition steps in the range of 439-738 K. Various equations like Coats-Redfern (CR), Horowitz-Metzger (HM) and Broido equations (BE) were applied to evaluate the energy of activation. The values of energy of activation are observed to be in the following order for both copper groundnut benzothiazole (CGB) and copper sesame benzothiazole (CSeB) complexes: CGB > CSeB. CGB is observed to be more stable than CSeB due to its higher activation energy. The above studies would provide significant information regarding the applications of synthesized agrochemicals and their safe removal through parameters obtained in degradation curves and its relation with energy.

New design of experiment combined with UV-Vis spectroscopy for extraction and estimation of polyphenols from Basil seeds, Red seeds, Sesame seeds and Ajwan seeds

NASA Astrophysics Data System (ADS)

Mabood, Fazal; Gilani, Syed Abdullah; Hussain, Javid; Alshidani, Sulaiman; Alghawi, Said; Albroumi, Mohammed; Alameri, Saif; Jabeen, Farah; Hussain, Zahid; Al-Harrasi, Ahmed; Al Abri, Zahra K. M.; Farooq, Saima; Naureen, Zakira; Hamaed, Ahmad; Rasul Jan, M.; Shah, Jasmin

2017-05-01

New experimental designs for the extraction of polyphenols from different seeds including Basil seed, Red seed, Sesame seeds and Ajwan seeds were investigated. Four variables the concentration and volume of methanol and NaOH solutions as well as the temperature and time of extraction were varied to see their effect on total phenol extraction. The temperature was varied in the range from 25 °C to 200 °C while the time in the range from 30 to 200 minutes. Response surface methodology was used to optimize the extraction parameters. The estimation of polyphenols was measured through phenols reduction UV-Vis spectroscopic method of phosphotungstic-phosphomolybdic acids (Folin-Ciocalteu's reagent). Calibration curve was made by using tannic acid as a polyphenols standard in the concentration range from 0.1 to 10 ppm. The regression line obtained shows the value of correlation coefficient i.e. R = 0.930 and Root mean square error of cross validation (RMSEC) value of 0.0654. The Basil seeds were found containing the highest amount of total phenols i.e. 785.76 mg/100 g. While the Sesame seeds having the least amount i.e. 33.08 mg/100 g. The Ajwan seeds and the Red seeds are containing the medium amounts i.e. 379 mg/100 g and 220.54 mg/100 g respectively.

Dietary Fats

MedlinePlus

... canola, olive, safflower, sesame, or sunflower. Of course, eating too much fat will put on the pounds. Fat has twice as many calories as proteins or carbohydrates. NIH: National Heart, Lung, and Blood ...

Peanut Allergy

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food ... food allergies. Peanuts are not the same as tree nuts (almonds, cashews, walnuts, etc.), which grow on ...

[Genetic control of the isocitrate dehydrogenase and shikimate dehydrogenase isoenzyme systems in Sesame (Sesamun indicum L.)].

PubMed

Díaz, Antonio J; Layrisse, Alfredo J

2002-01-01

Taking into consideration that the ideal manipulation of isozymic markers needs knowledge of their genetic control, the aim of this study was to establish the inheritance and linkage degree of loci that control the expression of two sesame isozyme systems: isocitrate dehydrogenase (IDH) and shikimate dehydrogenase (SKD). The F2 electrophoretic behaviour of IDH and SKD from cultivars Turen x Arawaca cross was evaluated. The results suggest that IDH is controlled by two loci, Idh1 and Idh2 meanwhile SKD by only one, Skd1. The loci Idh1 and Skd1 showed three distinguishable patterns, corresponding to the homocygote genotypes and the heterocygote one, adjusted to a one-character common mendelian segregation 1:2:1. Cosegregation between Idh1 and Skd1 was independent.

What Is ALS?

MedlinePlus

... Sesame Street” creator Jon Stone, boxing champion Ezzard Charles, NBA Hall of Fame basketball player George Yardley, ... photographer Eddie Adams, entertainer Dennis Day, jazz musician Charles Mingus, former vice president of the United States ...

7 CFR 1412.1 - Applicability, statutory changes, interest, and contract provisions.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., oats, upland cotton, rice, peanuts, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other designated oilseeds as determined and announced...

7 CFR 1412.1 - Applicability, statutory changes, interest, and contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., oats, upland cotton, rice, peanuts, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other designated oilseeds as determined and announced...

Symptoms

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

"Ozone" - the new NEMESIS of canker sore.

PubMed

Dharmavaram, Ayesha Thabusum; Reddy, R Sudhakara; Nallakunta, Rajesh

2015-03-01

Recurrent aphthous ulceration or recurrent aphthous stomatitis is one of the most debilitating and painful oral mucosal disease. This disease entity has no specific cause to occur and no proper laboratory procedures are present to elicit the diagnosis. The treatment options are largely palliative and aimed at reducing symptoms thereby improving patient's oral condition. In the present study the subjects witnessed alleviation of clinical symptoms related to the aphthous ulceration. The aim of the study was to explore the effectiveness of ozonated oil in the treatment of recurrent aphthous ulcer and to compare with sessame oil in order to analyse the effectiveness between the two topical oil medications. A single-blinded placebo-controlled trial comprising of 30 subjects with recurrent aphthous ulcers were divided into Group 1, Group 2 and Group 3 with 10 subjects in each group was performed. Patients in Group 1 received ozonated oil, Group 2 received sesame oil and Group 3 received placebo. Treatment response was assessed by measures of pain reduction, ulcer duration on 2(nd), 4(th) and 6(th) day. Data were analyzed using Wilcokson signed rank test and Friedman test. Participants treated with ozonated oil showed significant reduction in ulcer size, erythema and also alleviated the ulcer pain on 4(th) day of evaluation when compared to sesame oil and placebo group. On 6(th) day subjects treated with ozonated oil and sesame oil showed significant reduction in ulcer size and erythema. No significant difference was observed in placebo group when compared with other two groups on subsequent 2(nd), 4(th) and 6(th) day of evaluation. Ozonated oil and sessame oil, both showed similar effectiveness in relieving the ulcer pain. Ozone with its wide variety of inherent properties has proven to be choice of treatment in completely relieving the ulcer pain and ulcer size when compared with that of its counter medication (i.e. sesame oil).Therefore the results obtained in the present study forecast ozone to be used as a novel treatment approach in recurrent aphthous ulcers.

“Ozone” – The New Nemesis of Canker Sore

PubMed Central

Reddy, R. Sudhakara; Nallakunta, Rajesh

2015-01-01

Background: Recurrent aphthous ulceration or recurrent aphthous stomatitis is one of the most debilitating and painful oral mucosal disease. This disease entity has no specific cause to occur and no proper laboratory procedures are present to elicit the diagnosis. The treatment options are largely palliative and aimed at reducing symptoms thereby improving patient’s oral condition. In the present study the subjects witnessed alleviation of clinical symptoms related to the aphthous ulceration. Aims and objectives: The aim of the study was to explore the effectiveness of ozonated oil in the treatment of recurrent aphthous ulcer and to compare with sessame oil in order to analyse the effectiveness between the two topical oil medications. Materials and Methods: A single-blinded placebo-controlled trial comprising of 30 subjects with recurrent aphthous ulcers were divided into Group 1, Group 2 and Group 3 with 10 subjects in each group was performed. Patients in Group 1 received ozonated oil, Group 2 received sesame oil and Group 3 received placebo. Treatment response was assessed by measures of pain reduction, ulcer duration on 2nd, 4th and 6th day. Data were analyzed using Wilcokson signed rank test and Friedman test. Results: Participants treated with ozonated oil showed significant reduction in ulcer size, erythema and also alleviated the ulcer pain on 4th day of evaluation when compared to sesame oil and placebo group. On 6th day subjects treated with ozonated oil and sesame oil showed significant reduction in ulcer size and erythema. No significant difference was observed in placebo group when compared with other two groups on subsequent 2nd, 4th and 6th day of evaluation. Conclusion: Ozonated oil and sessame oil, both showed similar effectiveness in relieving the ulcer pain. Ozone with its wide variety of inherent properties has proven to be choice of treatment in completely relieving the ulcer pain and ulcer size when compared with that of its counter medication (i.e. sesame oil).Therefore the results obtained in the present study forecast ozone to be used as a novel treatment approach in recurrent aphthous ulcers. PMID:25954693

To Tell the Tooth

MedlinePlus

... Oral Health Made Easy Sesame Street Activity Sheets + Games and Quizzes Visit the Dentist with Marty To ... Dental Health Curriculum Dental Health Demonstrations MouthHealthy Kids > Games and Quizzes > To Tell the Tooth To Tell ...

Shellfish Allergy

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

Taking Care of Yourself

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

Living Well Everyday

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

Treatment and Managing Reactions

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

Dissociation, aggregation of sesame alpha-globulin in nonionic detergent solution.

PubMed

Lakshmi, T S; Nandi, P K

1978-10-01

Nonionic detergents Triton X-100 and Brij 36T induce dissociation and aggregation of the protein sesame alpha-globulin above the critical micelle concentrations (cmc) of the detergents. Spectrophotometric titration in Triton shows no change in the pKInt value of the tyrosyl groups at 1x10-3 M detergent where both dissociation and aggregation of the protein are observed. Fluorescence measurement does not indicate any change in the environment of the tryptophan groups of the protein in Brij. Viscosity measurements show no major conformational change of the protein in the detergent solution. Binding measurements suggest that perhaps micelles of the detergent predominantly bind to the protein. The detergent micelles preferentially bind to the exposed hydrophobic surfaces of the protein subunits. The association of the protein detergent complex through electrostatic interaction is probably responsible for the formation of the aggregates.

Pre-inverted SESAME data table construction enhancements to correct unexpected inverse interpolation pathologies in EOSPAC 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pimentel, David A.; Sheppard, Daniel G.

It was recently demonstrated that EOSPAC 6 continued to incorrectly create and interpolate pre-inverted SESAME data tables after the release of version 6.3.2beta.2. Significant interpolation pathologies were discovered to occur when EOSPAC 6's host software enabled pre-inversion with the EOS_INVERT_AT_SETUP option. This document describes a solution that uses data transformations found in EOSPAC 5 and its predecessors. The numerical results and performance characteristics of both the default and pre-inverted interpolation modes in both EOSPAC 6.3.2beta.2 and the fixed logic of EOSPAC 6.4.0beta.1 are presented herein, and the latter software release is shown to produce significantly-improved numerical results for the pre-invertedmore » interpolation mode.« less

SESAME: a software tool for the numerical dosimetric reconstruction of radiological accidents involving external sources and its application to the accident in Chile in December 2005.

PubMed

Huet, C; Lemosquet, A; Clairand, I; Rioual, J B; Franck, D; de Carlan, L; Aubineau-Lanièce, I; Bottollier-Depois, J F

2009-01-01

Estimating the dose distribution in a victim's body is a relevant indicator in assessing biological damage from exposure in the event of a radiological accident caused by an external source. This dose distribution can be assessed by physical dosimetric reconstruction methods. Physical dosimetric reconstruction can be achieved using experimental or numerical techniques. This article presents the laboratory-developed SESAME--Simulation of External Source Accident with MEdical images--tool specific to dosimetric reconstruction of radiological accidents through numerical simulations which combine voxel geometry and the radiation-material interaction MCNP(X) Monte Carlo computer code. The experimental validation of the tool using a photon field and its application to a radiological accident in Chile in December 2005 are also described.

Sinbase: an integrated database to study genomics, genetics and comparative genomics in Sesamum indicum.

PubMed

Wang, Linhai; Yu, Jingyin; Li, Donghua; Zhang, Xiurong

2015-01-01

Sesame (Sesamum indicum L.) is an ancient and important oilseed crop grown widely in tropical and subtropical areas. It belongs to the gigantic order Lamiales, which includes many well-known or economically important species, such as olive (Olea europaea), leonurus (Leonurus japonicus) and lavender (Lavandula spica), many of which have important pharmacological properties. Despite their importance, genetic and genomic analyses on these species have been insufficient due to a lack of reference genome information. The now available S. indicum genome will provide an unprecedented opportunity for studying both S. indicum genetic traits and comparative genomics. To deliver S. indicum genomic information to the worldwide research community, we designed Sinbase, a web-based database with comprehensive sesame genomic, genetic and comparative genomic information. Sinbase includes sequences of assembled sesame pseudomolecular chromosomes, protein-coding genes (27,148), transposable elements (372,167) and non-coding RNAs (1,748). In particular, Sinbase provides unique and valuable information on colinear regions with various plant genomes, including Arabidopsis thaliana, Glycine max, Vitis vinifera and Solanum lycopersicum. Sinbase also provides a useful search function and data mining tools, including a keyword search and local BLAST service. Sinbase will be updated regularly with new features, improvements to genome annotation and new genomic sequences, and is freely accessible at http://ocri-genomics.org/Sinbase/. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Evaluation of a Multimedia Intervention for Children and Families Facing Multiple Military Deployments.

PubMed

Flittner O'Grady, Allison; Thomaseo Burton, E; Chawla, Neelu; Topp, David; MacDermid Wadsworth, Shelley

2016-02-01

Repeated military deployments have been a common experience for many military families in the past 15 years. While there has been an increase in research and intervention focused on the effects on families of military deployments, much of this work has not focused specifically on the particular needs of young children. Talk, Listen, Connect: Multiple Deployments (TLC-II MD), a multimedia kit designed for home use, is among the first interventions directed toward young children. Created by Sesame Workshop and using popular Sesame Street characters, TLC-II MD was designed to support and equip families with young children with skills to address challenges associated with multiple deployments. This study utilized a randomized experimental design to evaluate the impact of TLC-II MD relative to a control condition using a Sesame Workshop multimedia kit not tailored to military families. Parents in both groups reported that children enjoyed the video overall and watched it repeatedly. Also in both groups, caregivers' depressive symptoms and children's aggressive behaviors declined significantly over time. Caregivers in the test group reported significantly larger increases in comfort discussing the deployment with their child and stronger perceptions that the DVD helped children to cope. Thus, the resilience-oriented materials were helpful to both groups, but those tailored to military families were significantly more likely to be perceived as helpful. Findings offer evidence regarding the ability of multimedia self-administered interventions to assist military families.

New design of experiment combined with UV-Vis spectroscopy for extraction and estimation of polyphenols from Basil seeds, Red seeds, Sesame seeds and Ajwan seeds.

PubMed

Mabood, Fazal; Gilani, Syed Abdullah; Hussain, Javid; Alshidani, Sulaiman; Alghawi, Said; Albroumi, Mohammed; Alameri, Saif; Jabeen, Farah; Hussain, Zahid; Al-Harrasi, Ahmed; Al Abri, Zahra K M; Farooq, Saima; Naureen, Zakira; Hamaed, Ahmad; Rasul Jan, M; Shah, Jasmin

2017-05-05

New experimental designs for the extraction of polyphenols from different seeds including Basil seed, Red seed, Sesame seeds and Ajwan seeds were investigated. Four variables the concentration and volume of methanol and NaOH solutions as well as the temperature and time of extraction were varied to see their effect on total phenol extraction. The temperature was varied in the range from 25°C to 200°C while the time in the range from 30 to 200minutes. Response surface methodology was used to optimize the extraction parameters. The estimation of polyphenols was measured through phenols reduction UV-Vis spectroscopic method of phosphotungstic-phosphomolybdic acids (Folin-Ciocalteu's reagent). Calibration curve was made by using tannic acid as a polyphenols standard in the concentration range from 0.1 to 10ppm. The regression line obtained shows the value of correlation coefficient i.e. R=0.930 and Root mean square error of cross validation (RMSEC) value of 0.0654. The Basil seeds were found containing the highest amount of total phenols i.e. 785.76mg/100g. While the Sesame seeds having the least amount i.e. 33.08mg/100g. The Ajwan seeds and the Red seeds are containing the medium amounts i.e. 379mg/100g and 220.54mg/100g respectively. Copyright © 2017 Elsevier B.V. All rights reserved.

Starter Culture Selection for Making Chinese Sesame-Flavored Liquor Based on Microbial Metabolic Activity in Mixed-Culture Fermentation

PubMed Central

Wu, Qun; Ling, Jie

2014-01-01

Selection of a starter culture with excellent viability and metabolic activity is important for inoculated fermentation of traditional food. To obtain a suitable starter culture for making Chinese sesame-flavored liquor, the yeast and bacterium community structures were investigated during spontaneous and solid-state fermentations of this type of liquor. Five dominant species in spontaneous fermentation were identified: Saccharomyces cerevisiae, Pichia membranaefaciens, Issatchenkia orientalis, Bacillus licheniformis, and Bacillus amyloliquefaciens. The metabolic activity of each species in mixed and inoculated fermentations of liquor was investigated in 14 different cocultures that used different combinations of these species. The relationships between the microbial species and volatile metabolites were analyzed by partial least-squares (PLS) regression analysis. We found that S. cerevisiae was positively correlated to nonanal, and B. licheniformis was positively associated with 2,3-butanediol, isobutyric acid, guaiacol, and 4-vinyl guaiacol, while I. orientalis was positively correlated to butyric acid, isovaleric acid, hexanoic acid, and 2,3-butanediol. These three species are excellent flavor producers for Chinese liquor. Although P. membranaefaciens and B. amyloliquefaciens were not efficient flavor producers, the addition of them alleviated competition among the other three species and altered their growth rates and flavor production. As a result, the coculture of all five dominant species produced the largest amount of flavor compounds. The result indicates that flavor producers and microbial interaction regulators are important for inoculated fermentation of Chinese sesame-flavored liquor. PMID:24814798

Facts and Statistics about Food Allergies

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food ... reactions. Eight major food allergens – milk, egg, peanut, tree nuts, wheat, soy, fish and crustacean shellfish – are ...

Managing Food Allergies at Home

MedlinePlus

... of reactions. Learn more here. Milk Egg Peanut Tree Nuts Soy Wheat Fish Shellfish Sesame Other Food Allergens Allergy Alerts Research Programs Research Programs We are the world’s largest private source of food allergy research funding. ...

Protect Your Heart: Choose Healthy Fats

MedlinePlus

... by lowering your cholesterol. Another protective fat, called omega-3 fats, is found in some types of fish, ... or sesame paste • safflower oil • walnuts • salad dressings Omega-3 fats: This type of fat helps prevent clogging ...

A preliminary look at AVE-SESAME 5 conducted on 20-21 May 1979

NASA Technical Reports Server (NTRS)

July, M.; Turner, R. E.

1981-01-01

Information on data collected, synoptic conditions, and severe and unusual weather reported during the period are presented. Records of the synoptic conditions include synoptic charts, radar charts, satellite photographs, and rainfall observations.

408-fs SESAM mode locked Cr:ZnSe laser

NASA Astrophysics Data System (ADS)

Bu, Xiangbao; Shi, Yuhang; Xu, Jia; Li, Huijuan; Wang, Pu

2018-01-01

We report self-starting femtosecond operation of a 127-MHz SESAM mode locked Cr:ZnSe laser around 2420 nm. A thulium doped double clad fiber laser at 1908 nm was used as the pumping source. In the normal dispersion regime, stable pulse pairs with constant phase differences in the multipulse regime were observed. The maximum output power was 342 mW with respect to incident pump power of 4.8 W and the corresponding slope efficiency was 10.4%. By inserting a piece of sapphire plate, dispersion compensation was achieved and the intra-cavity dispersion was moved to the anomalous regime. A maximum output power of 403 mW was obtained and the corresponding slope efficiency was 12.2%. Pulse width was measured to be 408 fs by a collinear autocorrelator using two-photon absorption in an InGaAs photodiode. The laser spectrum in multipulse operation showed a clear periodic modulation.

Quantifying equation-of-state and opacity errors using integrated supersonic diffusive radiation flow experiments on the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guymer, T. M., E-mail: Thomas.Guymer@awe.co.uk; Moore, A. S.; Morton, J.

A well diagnosed campaign of supersonic, diffusive radiation flow experiments has been fielded on the National Ignition Facility. These experiments have used the accurate measurements of delivered laser energy and foam density to enable an investigation into SESAME's tabulated equation-of-state values and CASSANDRA's predicted opacity values for the low-density C{sub 8}H{sub 7}Cl foam used throughout the campaign. We report that the results from initial simulations under-predicted the arrival time of the radiation wave through the foam by ≈22%. A simulation study was conducted that artificially scaled the equation-of-state and opacity with the intended aim of quantifying the systematic offsets inmore » both CASSANDRA and SESAME. Two separate hypotheses which describe these errors have been tested using the entire ensemble of data, with one being supported by these data.« less

Competitive adsorption of heavy metals onto sesame straw biochar in aqueous solutions.

PubMed

Park, Jong-Hwan; Ok, Yong Sik; Kim, Seong-Heon; Cho, Ju-Sik; Heo, Jong-Soo; Delaune, Ronald D; Seo, Dong-Cheol

2016-01-01

Objective of this research was to evaluate adsorption of heavy metals in mono and multimetal forms onto sesame straw biochar (SSB). Competitive sorption of metals by SSB has never been reported previously. The maximum adsorption capacities (mgg(-1)) of metals by SSB were in the order of Pb (102)≫Cd (86)≫Cr (65)>Cu (55)≫Zn (34) in the monometal adsorption isotherm and Pb (88)≫Cu (40)≫Cr (21)>Zn (7)⩾Cd (5) in the multimetal adsorption isotherm. Based on data obtained from the distribution coefficients, Freundlich and Langmuir adsorption models, and three-dimensional simulation, multimetal adsorption behaviors differed from monometal adsorption due to competition. Especially, during multimetal adsorption, Cd was easily exchanged and substituted by other metals. Further competitive adsorption studies are necessary in order to accurately estimate the heavy metal adsorption capacity of biochar in natural environments. Copyright © 2015 Elsevier Ltd. All rights reserved.

Hypersensitivities to sesame and other common edible seeds.

PubMed

Patel, A; Bahna, S L

2016-10-01

Several seeds have been increasingly incorporated in various food items, with consequent risk of hypersensitivity reactions that are often severe. Identification of the specific seed as the culprit is often not explored or is difficult to verify. In this article, we reviewed the English literature from January 1930 to March 2016 using PubMed and Google Scholar searching for publications relevant to hypersensitivity to common edible seeds, namely sesame, sunflower seed, poppy seed, pumpkin seed, flaxseed, and mustard seed. Considering the worldwide consumption of those seeds, the number of published articles on the subject was relatively small and was mainly as case reports rather than large series. Allergy to sesame was more reported than to other seeds, with an estimated prevalence of 0.1-0.2%. In this review, we summarize the information relevant to each of the six seeds and their oils regarding the manifestations, routes of exposure, identified major allergens, and cross-reactivity with other seeds or other foods. We also addressed the important role of a thorough history taking in suspecting seed allergy, the limited reliability of routine diagnostic procedures, and the importance of verification by appropriate challenge tests. At present, management is basically dietary avoidance and the use of symptomatic medications that may include epinephrine auto-injectors. We did not encounter any well-designed studies on immunotherapy for seed allergy, but it is hoped that such a gap be filled by the development of safe effective protocols in the near future. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

77 FR 66832 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

..., tallow wood, tea oil plant, and vernonia). Contact: Bethany Benbow, (703) 347-8072, email address: benbow... seed, rose hip, sesame, Stokes aster, sweet rocket, tallow wood, tea oil plant, and vernonia). Contact...

Breastfeeding: Hints to Help You Get Off to a Good Start

MedlinePlus

... you can get calcium from foods such as broccoli, sesame seeds, tofu, and kale. Talk to your ... that affect them. These may include spicy foods, broccoli, or milk. Some babies react to cow’s milk ...

Head Lice

MedlinePlus

What are head lice? Head lice are tiny insects that live on people's heads. Adult lice are about the size of sesame seeds. The eggs, called ... often at the neckline and behind the ears. Head lice are parasites, and they need to feed on ...

7 CFR 1412.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... grain rice, medium grain rice, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other oilseeds as determined by the Secretary. Crop year... Austrian, wrinkled seed, yellow, Umatilla, and green, excluding peas grown for the fresh, canning, or...

Physiological and enzymatic alterations in sesame seeds submitted to different osmotic potentials.

PubMed

Pires, R M O; Àvila, M A B; Leite, D G; Santos, H O; Souza, G A; Von Pinho, E V R

2017-08-17

With the imminence of global climate changes that affect the temperature and the rainfall uniformity, it is growing the concern about the adaptation of crops to the water deficit. Thus, the objective of this study was to evaluate alterations in physiological and enzymatic mechanisms during the germination process of sesame seeds under different water availability. To simulate the water restriction we used PEG6000, a high molecular weight molecule that does not penetrate the seed structure but allows different osmotic potentials. The treatments were -0.1, -0.2, and -0.3 MPa, and the control. Germination, first-count germination, germination velocity index, and length and dry mass of the hypocotyl and radicle were performed. The seeds were weighed before and after treatments every 3 h. After each weighing, 100 seeds were taken for analysis of the enzymes alcohol dehydrogenase (ADH), malate dehydrogenase, esterase, catalase (CAT), superoxide dismutase (SOD), isocitrate lyase (ICL), and glutamate dehydrogenase (GTDH). The statistical design was completely randomized with five replications. PEG6000 prolonged ADH activity during the beginning of germination, maintaining the anaerobic metabolism for longer. Subsequently, their activity was reduced, as well as ICL, favoring the deterioration of the seeds that take the time to germinate. Behavior was evidenced by the appearance of SOD, CAT, and GTDH isoforms after 24 h of imbibition when water restriction was imposed. Therefore, the PEG600 is efficient in simulating water deficit conditions in future scenarios of climate change, offering impotent information regarding the germination behavior of the plants under these conditions.

Enhanced generation of hydroxyl radicals on well-crystallized molybdenum trioxide/nano-graphite anode with sesame cake-like structure for degradation of bio-refractory antibiotic.

PubMed

Tang, Bo; Du, Jiannan; Feng, Qingmao; Zhang, Jiaqi; Wu, Dan; Jiang, Xiankai; Dai, Ying; Zou, Jinlong

2018-05-01

Anodic electro-catalysis oxidation is a highly effective way to solve the pollution problem of antibiotics in wastewater and receiving water bodies. In this study, for the first time, molybdenum trioxide/Nano-graphite (MoO 3 /Nano-G) composites are synthesized as anodic catalysts by a surfactant-assisted solvothermal method followed by low-temperature calcination. The effects of the proportion of MoO 3 to Nano-G (10, 30 and 50%) on the properties of composites are investigated through structural characterizations and electrochemical measurements. Results indicate that MoO 3 (30)/Nano-G electrode displays the electro-catalysis degradation efficiency of 99.9% towards ceftazidime, which is much higher than those of Nano-G (46.7%) and dimensionally stable anode (69.2%). The degradation mechanism for ceftazidime is studied by investigating the yields and kinds of active species. Results show that all of the OH, O 2- and H 2 O 2 are responsible for the electro-catalytic degradation process, and the produced OH radicals are the major active species for ceftazidime degradation. The synergistic effects between MoO 3 and Nano-G greatly contribute to the activation of H 2 O molecules to produce OH, meanwhile the special sesame cake-like structure facilitates to the exposure of contaminants to OH on active sites to enhance the degradation efficiency. These results suggest that MoO 3 /Nano-G electrodes can be considered as the promising catalysts for treating bio-refractory organic wastewater. Copyright © 2018 Elsevier Inc. All rights reserved.

The effect of combined photobiomodulation and curcumin on skin wound healing in type I diabetes in rats.

PubMed

Soleimani, Hasan; Amini, Abdollah; Taheri, Soudabeh; Sajadi, Ensieh; Shafikhani, Sasha; Schuger, Lucia A; Reddy, Vijaya B; Ghoreishi, Seyed Kamran; Pouriran, Ramin; Chien, Sufan; Bayat, Mohammad

2018-04-01

The purpose of the present scientific study was to analyze the effects of combined pulsed wave Photobiomodulation (PW PBM) and Curcumin on the microbial flora; in addition, the tensiometrical wounds properties for type one diabetes mellitus (TIDM) in an experimental animal model. TIDM induction was performed in thirty rats. In the entire animals, one full-thickness excision was implemented on their backs. Randomly, the divisions of rats into 5 groups took place. The primary group was considered as the control group and did not receive any treatment. The secondary group (placebo) received sesame oil by gastric gavage. The third group received PWPBM (890 nm, 80 Hz, 0.2 J/cm 2 ). The fourth group received curcumin (40 mg/kg, which was dissolved in sesame oil) by gastric gavage. Eventually, the fifth group received PW PBM + curcumin. Precisely, on day 7, microbiological examinations, and on the 15th day microbiological and tensiometrical examinations were conducted. The data were analyzed by statistical tests. PW PBM, significantly exacerbated tensiometrical properties of the TIDM repairing wound. PW PBM, curcumin, and PWPBM + curcumin significantly decreased colony forming units compared to the control and the placebo groups indeed. It was remarkably attained that PW PBM significantly accelerated the process of wound healing in the STZ-induced TIDM. The PW PBM was statistically more compelling compared to the curcumin and PWPBM + curcumin. PW PBM, curcumin, and PWPBM + curcumin significantly decreased colony forming units compared to the control and placebo groups. Copyright © 2018. Published by Elsevier B.V.

Melanin nanoparticles derived from a homology of medicine and food for sentinel lymph node mapping and photothermal in vivo cancer therapy.

PubMed

Chu, Maoquan; Hai, Wangxi; Zhang, Zheyu; Wo, Fangjie; Wu, Qiang; Zhang, Zefei; Shao, Yuxiang; Zhang, Ding; Jin, Lu; Shi, Donglu

2016-06-01

The use of non-toxic or low toxicity materials exhibiting dual functionality for use in sentinel lymph node (SLN) mapping and cancer therapy has attracted considerable attention during the past two decades. Herein, we report that the natural black sesame melanin (BSM) extracted from black sesame seeds (Sesamum indicum L.) shows exciting potential for SLN mapping and cancer photothermal therapy. Aqueous solutions of BSM under neutral and alkaline conditions can assemble into sheet-like nanoparticles ranging from 20 to 200 nm in size. The BSM nanoparticles were encapsulated by liposomes to improve their water solubility and the encapsulated and bare BSM nanoparticles were both non-toxic to cells. Furthermore, the liposome-encapsulated BSM nanoparticles (liposome-BSM) did not exhibit any long-term toxicity in mice. The liposome-BSM nanoparticles were subsequently used to passively target healthy and tumor-bearing mice SLNs, which were identified by the black color of the nanoparticles. BSM also strongly absorbed light in the near-infrared (NIR) range, which was rapidly converted to heat energy. Human esophagus carcinoma cells (Eca-109) were killed efficiently by liposome-BSM nanocomposites upon NIR laser irradiation. Furthermore, mouse tumor tissues grown from Eca-109 cells were seriously damaged by the photothermal effects of the liposome-BSM nanocomposites, with significant tumor growth suppression compared with controls. Given that BSM is a safe and nutritious biomaterial that can be easily obtained from black sesame seed, the results presented herein represent an important development in the use of natural biomaterials for clinical SLN mapping and cancer therapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

Biopolymers production with carbon source from the wastes of a beer brewery industry

NASA Astrophysics Data System (ADS)

Wong, Phoeby Ai Ling

The main purpose of this study was to assess the potential and feasibility of malt wastes, and other food wastes, such as soy wastes, ice-cream wastes, confectionery wastes, vinegar wastes, milk waste and sesame oil, in the induction of biosynthesis of PHA, in the cellular assembly of novel PHA with improved physical and chemical properties, and in the reduction of the cost of PHA production. In the first part of the experiments, a specific culture of Alcaligenes latus DSM 1124 was selected to ferment several types of food wastes as carbon sources into biopolymers. In addition, the biopolymer production, by way of using malt waste, of microorganisms from municipal activated sludge was also investigated. In the second part, the experiments focused on the synthesis of biopolymer with a higher molecular mass via the bacterial strain, which was selected and isolated from sesame oil, identified as Staphylococcus epidermidis . Molecular weight and molecular weight distribution of PHB were studied by GPC. Molecular weight of PHB produced from various types of food wastes by Alcaligenes latus was higher than using synthetic sucrose medium as nutrient, however, it resulted in the reverse by Staphylococcus epidermidis. Thermal properties of biopolymers were studied by DSC and TG. Using malt wastes as nutrients by Alcaligenes latus gave a higher melting temperature. Using sucrose, confectionery and sesame oil as nutrients by Staphylococcus epidermidis gave higher melting temperature. Optimization was carried out for the recovery of microbial PHB from Alcaligenes latus. Results showed that molecular weight can be controlled by changing the hypochlorite concentration, the ratio of chloroform to hypochlorite solution and the extraction time. In addition, the determination of PHB content by thermogravimetric analysis method with wet cell was the first report in our study. (Abstract shortened by UMI.)

Water-soluble fractions from defatted sesame seeds protect human neuroblast cells against peroxyl radicals and hydrogen peroxide-induced oxidative stress.

PubMed

Ben Othman, Sana; Katsuno, Nakako; Kitayama, Akemi; Fujimura, Makoto; Kitaguchi, Kohji; Yabe, Tomio

2016-09-01

Oxidative stress is involved in the development of aging-related diseases, such as neurodegenerative diseases. Dietary antioxidants that can protect neuronal cells from oxidative damage play an important role in preventing such diseases. Previously, we reported that water-soluble fractions purified from defatted sesame seed flour exhibit good antioxidant activity in vitro. In the present study, we investigated the protective effects of white and gold sesame seed water-soluble fractions (WS-wsf and GS-wsf, respectively) against 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) and hydrogen peroxide (H2O2) induced oxidative stress in human neuroblast SH-SY5Y cells. Pretreatment with WS-wsf and GS-wsf did not protect cells against AAPH-induced cytotoxicity, while simultaneous co-treatment with AAPH significantly improved cell viability and inhibited membrane lipid peroxidation. These results suggest that WS-wsf and GS-wsf protect cells from AAPH-induced extracellular oxidative damage via direct scavenging of peroxyl radicals. When oxidative stress was induced by H2O2, pretreatment WS-wsf and GS-wsf significantly enhanced cell viability. These results suggest that in addition to radical scavenging, WS-wsf and GS-wsf enhance cellular resistance to intracellular oxidative stress by activation of the Nrf-2/ARE pathway as confirmed by the increased Nrf2 protein level in the nucleus and increased heme oxygenase 1 (HO-1) mRNA expression. The roles of ferulic and vanillic acids as bioactive antioxidants in these fractions were also confirmed. In conclusion, our results indicated that WS-wsf and GS-wsf, which showed antioxidant activity in vitro, are also efficient antioxidants in a cell system protecting SH-SY5Y cells against both extracellular and intracellular oxidative stress.

Formative Research in the Production of Television for Children.

ERIC Educational Resources Information Center

Palmer, Edward L.

The Children's Television Workshop (CTW), responsible for the programs "Sesame Street" and "The Electric Company", conducted extensive research into the systematic use of television to promote the social, emotional, and intellectual growth of young children. Working without precedents in the field of formative research…

Readiness Based Sparing: A Research Summary

DTIC Science & Technology

2012-07-01

TIGER and SESAME. Retrieved from Defense Technical Information Center. (ADA283943) Geis, M. B., Camper, V. S., Measell , B. H., & Oi, J. S. (1995...Camper, V. S., & Measell , B. H. (1993). Aviation logistics support: Retail sparing issues. Retrieved from CNA. (2793002000) Kinskie, S. W. (1997). An

7 CFR 1421.9 - Basic loan rates.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., oats, grain sorghum, rice, peanuts, soybean, canola, flaxseed, mustard seed, rapeseed, safflower, sunflower seed, dry peas, lentils, chickpeas, crambe, sesame seed, wool, mohair and other crops designated... single loan rate in each county for each kind of other oilseeds, such as but not limited to, sunflower...

7 CFR 1421.9 - Basic loan rates.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., oats, grain sorghum, rice, peanuts, soybean, canola, flaxseed, mustard seed, rapeseed, safflower, sunflower seed, dry peas, lentils, chickpeas, crambe, sesame seed, wool, mohair and other crops designated... single loan rate in each county for each kind of other oilseeds, such as but not limited to, sunflower...

Can Multiculturalism Be Exported? Dilemmas of Diversity on Nigeria's "Sesame Square"

ERIC Educational Resources Information Center

Moland, Naomi A.

2015-01-01

While scholars argue that "multicultural education" initiatives are rooted in liberal Western ideals, such projects are increasingly being exported to non-Western countries with significantly different sociohistorical contexts. This article examines the adaptation of multicultural education on the Nigerian version of "Sesame…

A Transactional Approach to "Sing" by Raposo and Lichtenheld

ERIC Educational Resources Information Center

Cardany, Audrey Berger

2014-01-01

Tom Lichtenheld shares a new story of the power of music by illustrating Joe Raposo's classic "Sesame Street" song "Sing." In addition to lesson suggestions for general music classes, a discussion of and application to the theory of transactional reading are included.

Characteristics of ageostrophic flow in the vicinity of a severe weather outbreak - AVE-SESAME I

NASA Technical Reports Server (NTRS)

Arnold, J. E.

1982-01-01

GOES satellite data was used to examine the ageostrophic flow in the vicinity of severe weather outbreaks along the Red River between Texas and Oklahoma in April 1979. The observations were part of the NASA AVE-SESAME I data on atmospheric states close to severe weather conditions. The Barnes Objective Analysis Technique was employed to analyze the data on a 100 km grid. The ageostrophic wind was defined on a regional scale from satellite data on different levels of cloud wind vectors, with a height change signalling a short-wave system in a long-wave trough. The percentage of deviation of the subgeostrophic winds from the geostrophic wind was calculated, and maximum departure corresponded with the region of greatest storm development. Time cross sections of additions to the ageostrophic flow were made as a function of pressure at 100 mb intervals from 900-100 mb. The ageostrophic acceleration was consistently twice the geostrophic acceleration.

Motion performance and mooring system of a floating offshore wind turbine

NASA Astrophysics Data System (ADS)

Zhao, Jing; Zhang, Liang; Wu, Haitao

2012-09-01

The development of offshore wind farms was originally carried out in shallow water areas with fixed (seabed mounted) structures. However, countries with limited shallow water areas require innovative floating platforms to deploy wind turbines offshore in order to harness wind energy to generate electricity in deep seas. The performances of motion and mooring system dynamics are vital to designing a cost effective and durable floating platform. This paper describes a numerical model to simulate dynamic behavior of a new semi-submersible type floating offshore wind turbine (FOWT) system. The wind turbine was modeled as a wind block with a certain thrust coefficient, and the hydrodynamics and mooring system dynamics of the platform were calculated by SESAM software. The effect of change in environmental conditions on the dynamic response of the system under wave and wind loading was examined. The results indicate that the semi-submersible concept has excellent performance and SESAM could be an effective tool for floating wind turbine design and analysis.

Sesamol induced apoptotic effect in lung adenocarcinoma cells through both intrinsic and extrinsic pathways.

PubMed

Siriwarin, Boondaree; Weerapreeyakul, Natthida

2016-07-25

Sesamol is a phenolic lignan found in sesame seeds (Sesamum indicum L.) and sesame oil. The anticancer effects and molecular mechanisms underlying its apoptosis-inducing effect were investigated in human lung adenocarcinoma (SK-LU-1) cells. Sesamol inhibited SK-LU-1 cell growth with an IC50 value of 2.7 mM and exhibited less toxicity toward normal Vero cells after 48 h of treatment (Selective index = 3). Apoptotic bodies-the hallmark of apoptosis-were observed in sesamol-treated SK-LU-1 cells, stained with DAPI. Sesamol increased the activity of caspase 8, 9, and 3/7, indicating that apoptotic cell death occurred through both extrinsic and intrinsic pathways. Sesamol caused the loss of mitochondrial transmembrane potential signifying intrinsic apoptosis induction. Decreasing Bid expression revealed crosstalk between the intrinsic and extrinsic apoptotic pathways; demonstrating clearly that sesamol induces apoptosis through both pathways in human lung adenocarcinoma (SK-LU-1) cells. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The effects of water absorption and roasting conditions on fracture properties and internal structure of sesame seeds.

PubMed

Katsuno, Nakako; Fujimura, Makoto; Hanya, Akira; Nishizu, Takahisa

2017-04-01

We investigated the effects of soaking, residence time before roasting and roasting conditions on the fracture properties and structure of the cross-section of sesame seeds. Soaking time affected only the size of the side voids of the seed cross-section. The fracture force and strain of the roasted seeds decreased as residence time increased. The center void of the roasted seeds, important for seed crispness increased as residence time increased. In contrast, the side void of the roasted seeds only increased with residence time during the first 10 min. Seeds roasted at higher temperatures had smaller fracture forces and larger central voids than those roasted at lower temperatures. During roasting at 300 °C, the fracture force and strain decreased as the center void ratio increased. Overall, both a sufficient time for moisture diffusion in the seeds and a high roasting temperature were necessary to produce crisp roasted seeds.

NOTE: Development of modified voxel phantoms for the numerical dosimetric reconstruction of radiological accidents involving external sources: implementation in SESAME tool

NASA Astrophysics Data System (ADS)

Courageot, Estelle; Sayah, Rima; Huet, Christelle

2010-05-01

Estimating the dose distribution in a victim's body is a relevant indicator in assessing biological damage from exposure in the event of a radiological accident caused by an external source. When the dose distribution is evaluated with a numerical anthropomorphic model, the posture and morphology of the victim have to be reproduced as realistically as possible. Several years ago, IRSN developed a specific software application, called the simulation of external source accident with medical images (SESAME), for the dosimetric reconstruction of radiological accidents by numerical simulation. This tool combines voxel geometry and the MCNP(X) Monte Carlo computer code for radiation-material interaction. This note presents a new functionality in this software that enables the modelling of a victim's posture and morphology based on non-uniform rational B-spline (NURBS) surfaces. The procedure for constructing the modified voxel phantoms is described, along with a numerical validation of this new functionality using a voxel phantom of the RANDO tissue-equivalent physical model.

Development of modified voxel phantoms for the numerical dosimetric reconstruction of radiological accidents involving external sources: implementation in SESAME tool.

PubMed

Courageot, Estelle; Sayah, Rima; Huet, Christelle

2010-05-07

Estimating the dose distribution in a victim's body is a relevant indicator in assessing biological damage from exposure in the event of a radiological accident caused by an external source. When the dose distribution is evaluated with a numerical anthropomorphic model, the posture and morphology of the victim have to be reproduced as realistically as possible. Several years ago, IRSN developed a specific software application, called the simulation of external source accident with medical images (SESAME), for the dosimetric reconstruction of radiological accidents by numerical simulation. This tool combines voxel geometry and the MCNP(X) Monte Carlo computer code for radiation-material interaction. This note presents a new functionality in this software that enables the modelling of a victim's posture and morphology based on non-uniform rational B-spline (NURBS) surfaces. The procedure for constructing the modified voxel phantoms is described, along with a numerical validation of this new functionality using a voxel phantom of the RANDO tissue-equivalent physical model.

An analysis of the AVE-SESAME I period using statistical structure and correlation functions. [Atmospheric Variability Experiment-Severe Environmental Storm and Mesoscale Experiment

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Meyer, P. J.

1984-01-01

Structure and correlation functions are used to describe atmospheric variability during the 10-11 April day of AVE-SESAME 1979 that coincided with the Red River Valley tornado outbreak. The special mesoscale rawinsonde data are employed in calculations involving temperature, geopotential height, horizontal wind speed and mixing ratio. Functional analyses are performed in both the lower and upper troposphere for the composite 24 h experiment period and at individual 3 h observation times. Results show that mesoscale features are prominent during the composite period. Fields of mixing ratio and horizontal wind speed exhibit the greatest amounts of small-scale variance, whereas temperature and geopotential height contain the least. Results for the nine individual times show that small-scale variance is greatest during the convective outbreak. The functions also are used to estimate random errors in the rawinsonde data. Finally, sensitivity analyses are presented to quantify confidence limits of the structure functions.

The analysis and kinetic energy balance of an upper-level wind maximum during intense convection

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Jedlovec, G. J.

1982-01-01

The purpose of this paper is to analyze the formation and maintenance of the upper-level wind maximum which formed between 1800 and 2100 GMT, April 10, 1979, during the AVE-SESAME I period, when intense storms and tornadoes were experienced (the Red River Valley tornado outbreak). Radiosonde stations participating in AVE-SESAME I are plotted (centered on Oklahoma). National Meteorological Center radar summaries near the times of maximum convective activity are mapped, and height and isotach plots are given, where the formation of an upper-level wind maximum over Oklahoma is the most significant feature at 300 mb. The energy balance of the storm region is seen to change dramatically as the wind maximum forms. During much of its lifetime, the upper-level wind maximum is maintained by ageostrophic flow that produces cross-contour generation of kinetic energy and by the upward transport of midtropospheric energy. Two possible mechanisms for the ageostrophic flow are considered.

Estrogen replacement avoids the decrease of bladder innervations in ovariectomized adult virgin rats: in vivo stereological study.

PubMed

de Fraga, Rogerio; Palma, Paulo; Dambros, Miriam; Riccetto, Cassio L Z; Mandarim-de-Lacerda, Carlos; Miyaoka, Ricardo

2009-05-01

The authors quantified the nerve fibers in the bladder wall of ovariectomized rats with and without estradiol replacement. This study was conducted on 40 Wistar rats (3 months old). Group 1: remained intact; Group 2: underwent bilateral ovariectomy, and after 30 days was started on subcutaneous sesame oil replacement (0.2 ml per day) for 90 days; Group 3: sham-operated, and after 30 days was started on subcutaneous sesame oil replacement (0.2 ml per day) for 90 days; Group 4: bilateral ovariectomy, and after 30 days was started on subcutaneous injection of 17β-estradiol (10 μg/kg body weight) for 90 days. S-100 was used to stain nerves myelinized fibers on paraffin rat bladder sections. The G-50 grid system was used to quantitatively analyze the fibers. Long-term estrogen deprivation caused significant changes in bladder innervations, which can be characterized by a decreased number of nerve fibers by 65% (p < 0.001).

Synchrotron Light Sources in Developing Countries

NASA Astrophysics Data System (ADS)

Winick, Herman; Pianetta, Piero

The more than 50 light sources in operation include facilities in Brazil, Korea, and Taiwan which started in the 1980's when they were developing countries. They came on line in the 1990's and have since trained hundreds of graduate students. They have attracted mid-career diaspora scientists to return. Growing user communities have demanded more advanced facilities, leading to higher performance new light sources that are now coming into operation. Light sources in the developing world now include the following: ∖textbf{SESAME}in the Middle East which is scheduled to start research in 2017 (∖underline {www.sesame.org}); ∖textbf{The African Light Source}, in the planning stage (∖underline {www.safricanlightsource.org}); and ∖textbf{The Mexican Light Source}, in the planning stage (∖underline {http://www.aps.org/units/fip/newsletters/201509/mexico.cfm}). See: http://wpj.sagepub.com/content/32/4/92.full.pdf +html; http://www.lightsources.org/press-release/2015/11/20/grenoble-resolutions-mark-historical-step-towards-african-light-source..

40 CFR 180.1087 - Sesame stalks; exemption from the requirement of a tolerance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... exemption from the requirement of a tolerance is established for residues of the biorational nematicide... fractions; potato; beet, sugar, roots; beet, sugar, tops; tomato; pepper, bell; squash; strawberry; eggplant...

40 CFR 180.1087 - Sesame stalks; exemption from the requirement of a tolerance.

Code of Federal Regulations, 2011 CFR

2011-07-01

... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... exemption from the requirement of a tolerance is established for residues of the biorational nematicide... fractions; potato; beet, sugar, roots; beet, sugar, tops; tomato; pepper, bell; squash; strawberry; eggplant...

Science on Television

ERIC Educational Resources Information Center

Stringer, John

2011-01-01

Television is frequently blamed for the problems adults face with some young people. Does television affect their understanding and behaviour? Of course it does. "Sesame Street", the most researched educational programme in the world, gave its pre-school viewers a head start in literacy that was still measurable ten years later. BBC…

Extending TOPS: Ontology-driven Anomaly Detection and Analysis System

NASA Astrophysics Data System (ADS)

Votava, P.; Nemani, R. R.; Michaelis, A.

2010-12-01

Terrestrial Observation and Prediction System (TOPS) is a flexible modeling software system that integrates ecosystem models with frequent satellite and surface weather observations to produce ecosystem nowcasts (assessments of current conditions) and forecasts useful in natural resources management, public health and disaster management. We have been extending the Terrestrial Observation and Prediction System (TOPS) to include a capability for automated anomaly detection and analysis of both on-line (streaming) and off-line data. In order to best capture the knowledge about data hierarchies, Earth science models and implied dependencies between anomalies and occurrences of observable events such as urbanization, deforestation, or fires, we have developed an ontology to serve as a knowledge base. We can query the knowledge base and answer questions about dataset compatibilities, similarities and dependencies so that we can, for example, automatically analyze similar datasets in order to verify a given anomaly occurrence in multiple data sources. We are further extending the system to go beyond anomaly detection towards reasoning about possible causes of anomalies that are also encoded in the knowledge base as either learned or implied knowledge. This enables us to scale up the analysis by eliminating a large number of anomalies early on during the processing by either failure to verify them from other sources, or matching them directly with other observable events without having to perform an extensive and time-consuming exploration and analysis. The knowledge is captured using OWL ontology language, where connections are defined in a schema that is later extended by including specific instances of datasets and models. The information is stored using Sesame server and is accessible through both Java API and web services using SeRQL and SPARQL query languages. Inference is provided using OWLIM component integrated with Sesame.

A summary of research on mesoscale energetics of severe storm environments

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.

1985-01-01

The goals of this research were to better understand interactions between areas of intense convection and their surrounding mesoscale environments by using diagnostic budgets of kinetic (KE) and available potential energy (APE). Three cases of intense convection were examined in detail. 1) Atmospheric Variability Experiments (AVE) carried out on 24 to 25 April 1975 were studied. Synoptic scale data at 3 to 6 hour intervals, contained two mesoscale convective complexes (MCCs). Analyses included total KE budgets and budgets of divergent and rotational components of KE. 2) AVE-Severe Environmental Storms and Mesoscale Experiments (SESAME)-4 carried out on 10 to 11 April 1979 were studied. Synotpic and meso alpha-scale data (250 km spacing, 3 hour intervals), contained the Red River Valley tornado outbreak. Analyses included total KE budgets (separate synoptic and mesoscale version), budgets for the divergent and rotational components, and the generation of APE by diabatic processes. 3) AVE-SESAME 5 studies were carried out on 20 to 31 May 1979. Synoptic and meso beta-scale data (75 km spacing, 1 1/2 to 3 hour intervals), contained a small MCC. Analyses include separate KE budgets for the synotic and meso beta-scales and a water vapor budget. Major findings of these investigations are: (1) The synoptic scale storm environment contains energy conversions and transports that are comparable to those of mature midlatitude cyclones. (2) Energetic in the mesoscale storm environment are often an order of magnitude larger than those in an undisturbed region. (3) Mesoscale wind maxima form in the upper troposphere on the poleward sides of convective areas, whereas speeds decrease south of storm regions.

Accelerated Burn Wound Closure in Mice with a New Formula Based on Traditional Medicine

PubMed Central

Mehrabani, Mehrnaz; Seyyedkazemi, Seyyed Mohsen; Nematollahi, Mohammad Hadi; Jafari, Elham; Mehrabani, Mitra; Mehdipour, Mohammad; Sheikhshoaee, Zahra; Mandegary, Ali

2016-01-01

Background A combination of the oils of sesame, hemp, wild pistachio, and walnut has been used for treatment of skin disorders, including wound burns, in some parts of Kerman, Iran. Evaluation of this remedy in the form of a pharmaceutical formulation in animal models can pave the way for its future application in wound burn healing in humans. Objectives This experimental study investigated the healing potential of a new formula (NF) based on folk medicine from Iran for the treatment of third degree burns in mice. The formula was a combination of the oils of four plants: sesame (Sesamum indicum L.), wild pistachio (Pistacia atlantica Desf.), hemp (Cannabis sativa L.), and walnut (Juglans regia L.) Methods Twenty-four mice were selected based on simple random sampling. Twenty-five percent of the total body surface area was burned by exposure to boiling water, according to the Walker-Mason method. NF and silver sulfadiazine (the positive control) were applied topically twice a day for 21 days. The burned area in the negative control group was left untreated. Epithelialization time and the percent of wound contraction were measured during the treatment period. The process of wound repairing was evaluated using histological (H and E and trichrome staining) and immunohistological (anti-pancytokeratin) methods. Results When compared to the controls, NF significantly improved wound contraction after day 10. Epithelialization time in the NF group was significantly faster than in the other groups (20 vs. 25.5 days) (P < 0.001). Histopathological and immunohistochemical findings confirmed the efficacy of the NF. Conclusions A new therapeutic remedy was introduced for the treatment of burn wounds. Further clinical and molecular studies are suggested to determine the exact mechanism(s) involved in the burn wound healing effect of NF. PMID:28191338

The Deer and the Duck.

ERIC Educational Resources Information Center

Palmer, Edward L.

This is a response to the criticism of "Sesame Street" by Herbert A. Sprigle in the December, 1972, issue of "Childhood Education." It is maintained that Sprigle misconstrued and misrepresented the program's mandate and objectives and that the design and reporting of his study are so flawed that his conclusions are virtually…

Screen Media and Young Children: Who Benefits?

ERIC Educational Resources Information Center

Cardany, Audrey Berger

2010-01-01

Since the airing of "Sesame Street" in 1985, television produced for children has expanded to more television shows and educational media that includes videos, DVDs, and computer products. Viewing screen media is pervasive in the environments of young children, and companies are designing products for our youngest viewers--infants and toddlers.…

Children's Television Workshop. Progress Report.

ERIC Educational Resources Information Center

Cooney, Joan Ganz

During the third quarter of 1973 (July through September) the Children's Television Workshop (CTW) evaluated old material and planned new programing. The fourth season of Sesame Street and the second season of The Electric Company were rerun through the summer by most of the public and commercial television stations that carried the shows…

Visual Literacy: Some Lessons from Children's Television Workshop.

ERIC Educational Resources Information Center

Fowles, Barbara R.; Horner, Vivian M.

With the pervasiveness of television, especially for children, visual literacy is a growing concern. Television should be regarded as part of a potential solution to the country's need for improved education. "Sesame Street" has proved that children do learn from television, that active interaction is not always necessary for learning,…

Xenophon’s Anabasis: Lessons in Leadership

DTIC Science & Technology

2007-06-01

in sesame, millet , panic, wheat, and barley.”59 Xenophon never blindly moved through terrain. He always closely observed his surroundings and was...apparent contradiction, he also gave the order that “peltasts were to advance with their fingers through their loops,…that the bowmen were to have

Is It Easier to Hop or Walk? Development Issues in Interface Design.

ERIC Educational Resources Information Center

Strommen, Erik F.

1993-01-01

Describes a study conducted by the Children's Television Workshop that tested two forms of Sesame Street character movement (i.e., discrete movement versus continuous motion) with three-year-old preschool children using a Nintendo controller. Cognitive factors governing children's game performance and implications for designing interactive…

7 CFR 1412.1 - Applicability, statutory changes, interest, and contract provisions.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., oats, upland cotton, rice, peanuts, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other designated oilseeds as determined and announced... contract. Also, if any refund comes due to CCC under this part, interest will be due from the date of the...

7 CFR 1412.1 - Applicability, statutory changes, interest, and contract provisions.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., oats, upland cotton, rice, peanuts, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other designated oilseeds as determined and announced... contract. Also, if any refund comes due to CCC under this part, interest will be due from the date of the...

7 CFR 1412.1 - Applicability, statutory changes, interest, and contract provisions.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., oats, upland cotton, rice, peanuts, soybeans, sunflower seed, rapeseed, canola, safflower, flaxseed, mustard seed, crambe, sesame seed, pulse crops, and other designated oilseeds as determined and announced... contract. Also, if any refund comes due to CCC under this part, interest will be due from the date of the...

The "Motherese" of Mr. Rogers: A Description of the Dialogue of Educational Television Programs.

ERIC Educational Resources Information Center

Rice, Mabel L.; Haight, Patti L.

Dialogue from 30-minute samples from "Sesame Street" and "Mr. Rogers' Neighborhood" was coded for grammar, content, and discourse. Grammatical analysis used the LINGQUEST computer-assisted language assessment program (Mordecai, Palen, and Palmer 1982). Content coding was based on categories developed by Rice (1984) and…

Effect of Prosocial Cartoons on Preschool Children.

ERIC Educational Resources Information Center

Forge, Karen L. S.; Phemister, Sherri

If live-model prosocial programs such as "Sesame Street" and "Mister Rogers' Neighborhood" can facilitate favorable behavior in preschoolers, as was shown by Rushton (1982), then it seems reasonable to suggest that cartoons might have a similar positive impact. This study sought to determine whether viewing a prosocial cartoon would be as…

EOS Interpolation and Thermodynamic Consistency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gammel, J. Tinka

2015-11-16

As discussed in LA-UR-08-05451, the current interpolator used by Grizzly, OpenSesame, EOSPAC, and similar routines is the rational function interpolator from Kerley. While the rational function interpolator is well-suited for interpolation on sparse grids with logarithmic spacing and it preserves monotonicity in 1-d, it has some known problems.

European commission research on stratospheric ozone depletion

NASA Astrophysics Data System (ADS)

Amanatidis, G. T.; Ott, H.

1995-02-01

The research policy of the European Commission (EC) on the stratospheric ozone depletion, which is implemented through the ENVIRONMENT Programme is described. The strategy of this stratospheric ozone research, which is developed to address the open scientific questions, requires a coordinated and balanced programme which is based on long term measurements, process studies at regional or global scale, laboratory studies, continuous and accurate measurements of ultraviolet (UV) radiation and development of instrumentation. These research activities, whenever necessary, take form of extensive and coordinated experiments (EASOE 1991/92, SESAME 1994-95), while the overall objective is to provide a firm scientific basis for future European Union (EU) policy actions in this area. Finally, priorities which have been identified for future research in the ENVIRONMENT and CLIMATE Programme (1994-1998) are also detailed.

Impact of applying edible oils to silk channels on ear pests of sweet corn

USDA-ARS?s Scientific Manuscript database

The impact of applying vegetable oils to corn silks on ear-feeding insects in sweet corn production was evaluated in 2006 and 2007. Six vegetable oils used in this experiment were canola, corn, olive, peanut, sesame, and soybean. Water and two commercial insecticidal oils (Neemix' neem oil and Sun...

The Impact of Infant-Directed Videos on Parent-Child Interaction

ERIC Educational Resources Information Center

Pempek, Tiffany A.; Demers, Lindsay B.; Hanson, Katherine G.; Kirkorian, Heather L.; Anderson, Daniel R.

2011-01-01

This study assessed whether infant-directed videos designed to promote parent-child interactions actually support such engagement. Parents watched videos from the "Baby Einstein" or the "Sesame Beginnings" series for 2 weeks at home with their 12- or 18-month-old infants. "Baby Einstein" encourages parents to label objects and actions; "Sesame…

Point of View--What Do We Mean by "Limited Attention Span"?

ERIC Educational Resources Information Center

Findley, Nicola

2005-01-01

Often times, teachers and prospective teachers repeat the "common knowledge" that young children have short attention spans. How often this becomes another self-fulfilling prophecy as teachers switch frequently from one activity to another, before student attention can wander, in an imitation of the Sesame Street model of teaching as…

7 CFR 1421.7 - Requesting marketing assistance loans and loan deficiency payments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... harvested: barley, canola, flaxseed, oats, rapeseed, crambe, sesame seed, and wheat. (2) May 31 of the year following the year in which the following crops are normally harvested: corn, grain sorghum, mustard seed, rice, safflower, soybeans, sunflower seed, dry peas, lentils, and chickpeas. (3) January 31 of the year...

7 CFR 1421.7 - Requesting marketing assistance loans and loan deficiency payments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... harvested: barley, canola, flaxseed, oats, rapeseed, crambe, sesame seed, and wheat. (2) May 31 of the year following the year in which the following crops are normally harvested: corn, grain sorghum, mustard seed, rice, safflower, soybeans, sunflower seed, dry peas, lentils, and chickpeas. (3) January 31 of the year...

The Children's Television Workshop; How and Why It Works. Final Report.

ERIC Educational Resources Information Center

Nassau County Board of Cooperative Educational Services, Westbury, NY.

A review of the operations of the Children's Television Workshop (CTW), the producer of Sesame Street and The Electric Company, is presented. The objective is to illustrate the organizational principles which CTW used to provide leadership, develop functional relationships among the various segments of a large-scale enterprise, and to harness…

Sesame Street Picnic: An Introductory Activity to Claims, Evidence, and Rationale

ERIC Educational Resources Information Center

Del Carlo, Dawn; Flokstra, Brittany

2017-01-01

Recent calls for reform in K-16 science, technology, engineering, and mathematics (STEM) education not only emphasize mastery of content, but also call for students to engage in the scientific practice of making evidence-based claims, or scientific argumentation (National Research Council, 2012; NGSS Lead States, 2013). However, students often…

Space Age Multi-CPU Computer Network Is Just for Fun and Education, Too.

ERIC Educational Resources Information Center

Technological Horizons in Education, 1980

1980-01-01

Describes the Sesame Place's Computer Gallery, 56 Apple II computers linked by three Nestar Cluster/One Model A hard disc systems, the first commercial permanent educational play park. Programs for this hands-on indoor/outdoor park as well as a description of the facility are given. (JN)

7 CFR 1421.7 - Requesting marketing assistance loans and loan deficiency payments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... agreement or loan deficiency payment application on or before the applicable final loan availability date... harvested: barley, canola, flaxseed, oats, rapeseed, crambe, sesame seed, and wheat. (2) May 31 of the year following the year in which the following crops are normally harvested: corn, grain sorghum, mustard seed...

7 CFR 1421.7 - Requesting marketing assistance loans and loan deficiency payments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... agreement or loan deficiency payment application on or before the applicable final loan availability date... harvested: barley, canola, flaxseed, oats, rapeseed, crambe, sesame seed, and wheat. (2) May 31 of the year following the year in which the following crops are normally harvested: corn, grain sorghum, mustard seed...

7 CFR 1421.7 - Requesting marketing assistance loans and loan deficiency payments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... agreement or loan deficiency payment application on or before the applicable final loan availability date... harvested: barley, canola, flaxseed, oats, rapeseed, crambe, sesame seed, and wheat. (2) May 31 of the year following the year in which the following crops are normally harvested: corn, grain sorghum, mustard seed...

The Jamaican Project. Final Report.

ERIC Educational Resources Information Center

Lasker, Harry

In 1972, a study was undertaken to test the reactions of media-inexperienced children in the Jamaican highlands to their first exposure to video-cassette-delivered episodes of "Sesame Street." Children were randomly selected from three different age groups: three to five-year-olds, six to eight-year-olds, and nine to eleven-year-olds.…

The Impact of Information Channel on Verbal Recall Among Preschool Aged Television Viewers.

ERIC Educational Resources Information Center

Welch, Alicia J.

A study investigated the learning impact of audio, visual, and audiovisual information channels in televised messages among preschool children. The messages consisted of a half-hour videotape of "Sesame Street" episodes (presented to 48 subjects), and a videotape of an intact "Mister Roger's Neighborhood" program (presented to…

21 CFR 172.854 - Polyglycerol esters of fatty acids.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Polyglycerol esters of fatty acids. 172.854... § 172.854 Polyglycerol esters of fatty acids. Polyglycerol esters of fatty acids, up to and including..., safflower oil, sesame oil, soybean oil, and tallow and the fatty acids derived from these substances...

19 CFR 10.56 - Vegetable oils, denaturing; release.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 1 2014-04-01 2014-04-01 false Vegetable oils, denaturing; release. 10.56 Section... Vegetable Oils § 10.56 Vegetable oils, denaturing; release. (a) Olive, palm-kernel, rapeseed, sunflower, and sesame oil shall be classifiable under subheadings 1509.10.20, 1509.10.40, 1509.90.20, 1509.90.40, 1510...

19 CFR 10.56 - Vegetable oils, denaturing; release.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Vegetable oils, denaturing; release. 10.56 Section... Vegetable Oils § 10.56 Vegetable oils, denaturing; release. (a) Olive, palm-kernel, rapeseed, sunflower, and sesame oil shall be classifiable under subheadings 1509.10.20, 1509.10.40, 1509.90.20, 1509.90.40, 1510...

19 CFR 10.56 - Vegetable oils, denaturing; release.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Vegetable oils, denaturing; release. 10.56 Section... Vegetable Oils § 10.56 Vegetable oils, denaturing; release. (a) Olive, palm-kernel, rapeseed, sunflower, and sesame oil shall be classifiable under subheadings 1509.10.20, 1509.10.40, 1509.90.20, 1509.90.40, 1510...

19 CFR 10.56 - Vegetable oils, denaturing; release.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Vegetable oils, denaturing; release. 10.56 Section... Vegetable Oils § 10.56 Vegetable oils, denaturing; release. (a) Olive, palm-kernel, rapeseed, sunflower, and sesame oil shall be classifiable under subheadings 1509.10.20, 1509.10.40, 1509.90.20, 1509.90.40, 1510...

19 CFR 10.56 - Vegetable oils, denaturing; release.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Vegetable oils, denaturing; release. 10.56 Section... Vegetable Oils § 10.56 Vegetable oils, denaturing; release. (a) Olive, palm-kernel, rapeseed, sunflower, and sesame oil shall be classifiable under subheadings 1509.10.20, 1509.10.40, 1509.90.20, 1509.90.40, 1510...

Children's Television Workshop. Quarterly Progress Report, July 30, 1982 to September 30, 1982.

ERIC Educational Resources Information Center

Children's Television Workshop, New York, NY.

The activities, research findings, and services of the Children's Television Workshop during a 3-month period are summarized. Research activities undertaken related to Sesame Street and staff meetings to disseminate that research are listed first; then, production completed or planned is outlined. Under community education services, the radio,…

Panwapa: Global Kids, Global Connections

ERIC Educational Resources Information Center

Berson, Ilene R.; Berson, Michael J.

2009-01-01

Panwapa, created by the Sesame Street Workshop of PBS, is an example of an initiative on the Internet designed to enhance students' learning by exposing them to global communities. Panwapa means "Here on Earth" in Tshiluba, a Bantu language spoken in the Democratic Republic of Congo. At the Panwapa website, www.panwapa.org, children aged…

NASA's participation in the AVE-SESAME '79 program

NASA Technical Reports Server (NTRS)

Hill, K.; Turner, R. E.; Wilson, G. S.

1979-01-01

NASA's Marshall Space Flight Center participated with its AVE (Atmospheric Variability Experiment) in a large interagency mesoscale and severe storms experiment identified herein as AVE-SESAME '79 (Atmospheric Variability Experiment-Severe Environmental Storms and Mesoscale Experiment 1979). A primary objective of NASA was to support an effort to acquire carefully edited sets of rawinsonde data during selected severe weather events for use in correlative and diagnostic studies with satellite and radar data obtained at approximately the same times. Data were acquired during six individual 24-h experiments on both the regional and storm scales over a network in the central United States that utilized approximately 20 supplemental rawinsonde sites meshed among 23 standard National Weather Service sites. Included among the six experiments are data obtained between 1200 GMT on April 10 and 1200 GMT on April 11, encompassing the formation and development period for the tornado-producing systems that devastated Wichita Falls, Texas, and other sections of Oklahoma and Texas. The other dates for which data sets are available are April 19-20 and 25-26, May 9-10 and 20-21, and June 7-8, 1979.

Effects of pH on protein components of extracted oil bodies from diverse plant seeds and endogenous protease-induced oleosin hydrolysis.

PubMed

Zhao, Luping; Chen, Yeming; Chen, Yajing; Kong, Xiangzhen; Hua, Yufei

2016-06-01

Plant seeds are used to extract oil bodies for diverse applications, but oil bodies extracted at different pH values exhibit different properties. Jicama, sunflower, peanut, castor bean, rapeseed, and sesame were selected to examine the effects of pH (6.5-11.0) on the protein components of oil bodies and the oleosin hydrolysis in pH 6.5-extracted oil bodies. In addition to oleosins, many extrinsic proteins (globulins, 2S albumin, and enzymes) were present in pH 6.5-extracted oil bodies. Globulins were mostly removed at pH 8.0, whereas 2S albumins were removed at pH 11.0. At pH 11.0, highly purified oil bodies were obtained from jicama, sunflower, peanut, and sesame, whereas lipase remained in the castor bean oil bodies and many enzymes in the rapeseed oil bodies. Endogenous protease-induced hydrolysis of oleosins occurred in all selected plant seeds. Oleosins with larger sizes were hydrolysed more quickly than oleosins with smaller sizes in each plant seed. Copyright © 2016 Elsevier Ltd. All rights reserved.

Prolonged exposure to a low-dose of bisphenol A increases spontaneous motor activity in adult male rats.

PubMed

Nojima, Kazuo; Takata, Tomoyo; Masuno, Hiroshi

2013-07-01

We investigated the effects of bisphenol A (BPA), an environmental endocrine-disrupting chemical, on spontaneous motor activity in adult male rats. The rats were implanted intraperitoneally with mini-osmotic pumps containing either BPA (50 μg/kg body weight per day) in sesame oil (BPA-treated group) or sesame oil only (vehicle-treated group). Spontaneous motor activity during a 24-h period was measured over 5 days from day 9 to day 13 after implantation using an animal movement analysis system. Spontaneous motor activity during the last 2 h of the dark phase and during the first 1-h of the light phase was increased in the BPA-treated group. Total spontaneous motor activity during the 12-h light phase, but not the 12-h dark phase, was higher in the BPA-treated group than in the vehicle-treated group. These findings suggest that BPA may induce hyperactivity in adult male rats during the 12-h light phase, especially during the 2 h immediately preceding sleep-onset and 1 h immediately following sleep-onset.

All-fiber wavelength-tunable picosecond nonlinear reflectivity measurement setup for characterization of semiconductor saturable absorber mirrors

NASA Astrophysics Data System (ADS)

Viskontas, K.; Rusteika, N.

2016-09-01

Semiconductor saturable absorber mirror (SESAM) is the key component for many passively mode-locked ultrafast laser sources. Particular set of nonlinear parameters is required to achieve self-starting mode-locking or avoid undesirable q-switch mode-locking for the ultra-short pulse laser. In this paper, we introduce a novel all-fiber wavelength-tunable picosecond pulse duration setup for the measurement of nonlinear properties of saturable absorber mirrors at around 1 μm center wavelength. The main advantage of an all-fiber configuration is the simplicity of measuring the fiber-integrated or fiber-pigtailed saturable absorbers. A tunable picosecond fiber laser enables to investigate the nonlinear parameters at different wavelengths in ultrafast regime. To verify the capability of the setup, nonlinear parameters for different SESAMs with low and high modulation depth were measured. In the operating wavelength range 1020-1074 nm, <1% absolute nonlinear reflectivity accuracy was demonstrated. Achieved fluence range was from 100 nJ/cm2 to 2 mJ/cm2 with corresponding intensity from 10 kW/cm2 to 300 MW/cm2.

Potential Interference of Oil Vehicles on Genital Tubercle Development during the Fetal Period in ICR Mice.

PubMed

Nishioka, Yasushi; Tamai, Kazuki; Onda, Masanari; Hiromori, Youhei; Kimura, Tomoki; Hu, Jianying; Nagase, Hisamitsu; Nakanishi, Tsuyoshi

2018-01-01

Corn oil, sesame oil, and 10% ethanol in corn oil are commonly used as dosing vehicles in toxicology studies. Since these vegetable oils contain bioactive compounds, it is important for toxicology studies to characterize the toxicities of the dosing vehicles themselves. It has been recently proposed that the width of the genital tubercle (GT), the dorsal-ventral length (D-V length) of the GT, and urethral tube closure in mouse fetuses can be used as novel markers for monitoring sexual development in mice. However, how these parameters are influenced by the dosing vehicles themselves remains unclear. Therefore, we evaluated the effects of corn oil, sesame oil, and 10% ethanol in corn oil on GT width, D-V length, and GT morphology in ICR mice. Our results showed that all three vehicles influenced GT width and D-V length, but not GT morphology, suggesting that the effects of dosing vehicles themselves might need to be considered when GT width or D-V length is used as a parameter to evaluate the effects of chemicals on GT development.

Novel depots of buprenorphine have a long-acting effect for the management of physical dependence to morphine.

PubMed

Liu, Kuo-Sheng; Kao, Cheng-Hsiung; Liu, Shyun-Yeu; Sung, K C; Kuei, Chun-Hsiung; Wang, Jhi-Joung

2006-03-01

Buprenorphine is a promising new pharmacotherapy for the management of physical dependence to opioids. The aim of the study was to evaluate the duration of action of several novel depots of buprenorphine in the treatment of physical dependence to morphine in mice. Following intramuscular injection, the duration of action of several novel oil-based depots of buprenorphine base in morphine-dependent mice were evaluated. The traditional dosage form of buprenorphine hydrochloride in saline was used as control. We found that the depot of buprenorphine base in sesame oil produced a dose-related long-lasting effect. On an equimolar basis of 6 micromol kg(-1), its effect was 5.7-fold longer than that of buprenorphine hydrochloride in saline. When prepared in several other oleaginous vehicles (castor oil, cottonseed oil, peanut oil and soybean oil), buprenorphine base also produced a long-lasting effect, which was similar to buprenorphine base in sesame oil. In conclusion, buprenorphine base, when prepared in oleaginous vehicles and injected intramuscularly in mice, produced a long-lasting effect on physical dependence to morphine.

First-principles equation of state of polystyrene and its effect on inertial confinement fusion implosions

DOE PAGES

Hu, S. X.; Collins, L. A.; Goncharov, V. N.; ...

2015-10-14

Obtaining an accurate equation of state (EOS) of polystyrene (CH) is crucial to reliably design inertial confinement fusion (ICF) capsules using CH/CH-based ablators. Thus, with first-principles calculations, we have investigated the extended EOS of CH over a wide range of plasma conditions (ρ = 0.1 to 100 g/cm 3 and T = 1,000 to 4,000,000 K). When compared with the widely used SESAME-EOS table, the first-principles equation of state (FPEOS) of CH has shown significant differences in the low-temperature regime, in which strong coupling and electron degeneracy play an essential role in determining plasma properties. Hydrodynamic simulations of cryogenic targetmore » implosions on OMEGA using the FPEOS table of CH have predicted ~5% reduction in implosion velocity and ~30% decrease in neutron yield in comparison with the usual SESAME simulations. This is attributed to the ~10% lower mass ablation rate of CH predicted by FPEOS. Simulations using CH-FPEOS show better agreement with measurements of Hugoniot temperature and scattered lights from ICF implosions.« less

Combination of Analytical and Chemometric Methods as a Useful Tool for the Characterization of Extra Virgin Argan Oil and Other Edible Virgin Oils. Role of Polyphenols and Tocopherols.

PubMed

Rueda, Ascensión; Samaniego-Sánchez, Cristina; Olalla, Manuel; Giménez, Rafael; Cabrera-Vique, Carmen; Seiquer, Isabel; Lara, Luis

2016-01-01

Analysis of phenolic profile and tocopherol fractions in conjunction with chemometrics techniques were used for the accurate characterization of extra virgin argan oil and eight other edible vegetable virgin oils (olive, soybean, wheat germ, walnut, almond, sesame, avocado, and linseed) and to establish similarities among them. Phenolic profile and tocopherols were determined by HPLC coupled with diode-array and fluorescence detectors, respectively. Multivariate factor analysis (MFA) and linear correlations were applied. Significant negative correlations were found between tocopherols and some of the polyphenols identified, but more intensely (P < 0.001) between the γ-tocopherol and oleuropein, pinoresinol, and luteolin. MFA revealed that tocopherols, especially γ-fraction, most strongly influenced the oil characterization. Among the phenolic compounds, syringic acid, dihydroxybenzoic acid, oleuropein, pinoresinol, and luteolin also contributed to the discrimination of the oils. According to the variables analyzed in the present study, argan oil presented the greatest similarity with walnut oil, followed by sesame and linseed oils. Olive, avocado, and almond oils showed close similarities.

First-principles equation of state of polystyrene and its effect on inertial confinement fusion implosions.

PubMed

Hu, S X; Collins, L A; Goncharov, V N; Kress, J D; McCrory, R L; Skupsky, S

2015-10-01

Obtaining an accurate equation of state (EOS) of polystyrene (CH) is crucial to reliably design inertial confinement fusion (ICF) capsules using CH/CH-based ablators. With first-principles calculations, we have investigated the extended EOS of CH over a wide range of plasma conditions (ρ=0.1to100g/cm(3) and T=1000 to 4,000,000 K). When compared with the widely used SESAME-EOS table, the first-principles equation of state (FPEOS) of CH has shown significant differences in the low-temperature regime, in which strong coupling and electron degeneracy play an essential role in determining plasma properties. Hydrodynamic simulations of cryogenic target implosions on OMEGA using the FPEOS table of CH have predicted ∼30% decrease in neutron yield in comparison with the usual SESAME simulations. This is attributed to the ∼5% reduction in implosion velocity that is caused by the ∼10% lower mass ablation rate of CH predicted by FPEOS. Simulations using CH-FPEOS show better agreement with measurements of Hugoniot temperature and scattered light from ICF implosions.

Thermal conductivity measurements of proton-heated warm dense aluminum

NASA Astrophysics Data System (ADS)

McKelvey, A.; Kemp, G.; Sterne, P.; Fernandez, A.; Shepherd, R.; Marinak, M.; Link, A.; Collins, G.; Sio, H.; King, J.; Freeman, R.; Hua, R.; McGuffey, C.; Kim, J.; Beg, F.; Ping, Y.

2017-10-01

We present the first thermal conductivity measurements of warm dense aluminum at 0.5-2.7 g/cc and 2-10 eV, using a recently developed platform of differential heating. A temperature gradient is induced in a Au/Al dual-layer target by proton heating, and subsequent heat flow from the hotter Au to the Al rear surface is detected by two simultaneous time-resolved diagnostics. A systematic data set allows for constraining both thermal conductivity and equation-of-state models. Simulations using Purgatorio model or Sesame S27314 for Al thermal conductivity and LEOS for Au/Al release equation-of-state show good agreement with data after 15 ps. Predictions by other models, such Lee-More, Sesame 27311 and 29373, are outside of experimental error bars. Discrepancy still exists at early time 0-15 ps, likely due to non-equilibrium conditions. (Y. Ping et al. Phys. Plasmas, 2015, A. Mckelvey, et al. Sci. Reports 2017). This work was performed under the auspices of the DOE by LLNL under contract DE-AC52-07NA27344 with support from DOE OFES Early Career program and LLNL LDRD program.

Sesame indicum, a nutritional supplement, elicits antiamnesic effect via cholinergic pathway in scopolamine intoxicated mice.

PubMed

Chidambaram, Saravana Babu; Pandian, Anbarasi; Sekar, Sathiya; Haridass, Sumathy; Vijayan, Ranju; Thiyagarajan, Lakshmi Kantham; Ravindran, Jayasree; Balaji Raghavendran, Hanumantha Rao; Kamarul, Tunku

2016-12-01

Present study was undertaken to evaluate the antiamnesic effect of Sesamum indicum (S. indicum) seeds (standardized for sesamin, a lignan, content) in scopolamine, a muscarinic antagonist intoxicated mice. Male Swiss albino mice (18-22 g bw) were pretreated with methanolic extract of sesame seeds (MSSE) (100 and 200 mg/kg/day, p.o) for a period of 14 days. Scopolamine (0.3 mg/kg, i.p.) was injected on day 14, 45 ± 10 min after MSSE administration. Antiamnesic effect of MSSE was evaluated using step-down latency (SDL) on passive avoidance apparatus and transfer latency (TL) on an elevated plus maze. To unravel the mechanism of action, we examined the effects of MSSE on the genes such as acetyl cholinesterase (AChE), muscarinic receptor M1 subtype (mAChRM 1 ), and brain derived neurotrophic factor (BDNF) expression within hippocampus of experimental mice. Further, its effects on bax and bcl-2 were also evaluated. Histopathological examination of hippocampal CA 1 region was performed using cresyl violet staining. MSSE treatment produced a significant and dose dependent increase in step down latency in passive avoidance test and decrease in transfer latency in elevated plus maze in scopolamine intoxicated injected mice. MSSE down-regulated AChE and mAChRM 1 and up-regulated BDNF mRNA expression. Further, it significantly down-regulated the bax and caspase 3 and up-regulated bcl-2 expression in scopolamine intoxicated mice brains. Mice treated with MSSE showed increased neuronal counts in hippocampal CA 1 region when compared with scopolamine-vehicle treated mice. Sesame seeds have the ability to interact with cholinergic components involved in memory function/restoration and also an interesting candidate to be considered for future cognitive research. © 2015 Wiley Periodicals, Inc. Environ Toxicol 31: 1955-1963, 2016. © 2015 Wiley Periodicals, Inc.

A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada.

PubMed

Ben-Shoshan, Moshe; Harrington, Daniel W; Soller, Lianne; Fragapane, Joseph; Joseph, Lawrence; St Pierre, Yvan; Godefroy, Samuel B; Elliott, Susan J; Elliot, Susan J; Clarke, Ann E

2010-06-01

Recent studies suggest an increased prevalence of food-induced allergy and an increased incidence of food-related anaphylaxis. However, prevalence estimates of food allergies vary considerably between studies. To determine the prevalence of peanut, tree nut, fish, shellfish, and sesame allergy in Canada. Using comparable methodology to Sicherer et al in the United States in 2002, we performed a cross-Canada, random telephone survey. Food allergy was defined as perceived (based on self-report), probable (based on convincing history or self-report of physician diagnosis), or confirmed (based on history and evidence of confirmatory tests). Of 10,596 households surveyed in 2008 and 2009, 3666 responded (34.6% participation rate), of which 3613 completed the entire interview, representing 9667 individuals. The prevalence of perceived peanut allergy was 1.00% (95% CI, 0.80%-1.20%); tree nut, 1.22% (95% CI, 1.00%-1.44%); fish, 0.51% (95% CI, 0.37%-0.65%); shellfish, 1.60% (95% CI, 1.35%-1.86%); and sesame, 0.10% (95% CI, 0.04%-0.17%). The prevalence of probable allergy was 0.93% (95% CI, 0.74%-1.12%); 1.14% (95% CI, 0.92%-1.35%); 0.48% (95% CI, 0.34%-0.61%); 1.42% (95% CI, 1.18%-1.66%); and 0.09% (95% CI, 0.03%-0.15%), respectively. Because of the infrequency of confirmatory tests and the difficulty in obtaining results if performed, the prevalence of confirmed allergy was much lower. This is the first nationwide Canadian study to determine the prevalence of severe food allergies. Our results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates. Copyright (c) 2010 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

Potential effect and mechanism of action of topical chamomile (Matricaria chammomila L.) oil on migraine headache: A medical hypothesis.

PubMed

Zargaran, Arman; Borhani-Haghighi, Afshin; Faridi, Pouya; Daneshamouz, Saeid; Kordafshari, Gholamreza; Mohagheghzadeh, Abdolali

2014-11-01

Migraine is a chronic recurring headache for which no complete treatment has been found yet. Therefore, finding new treatment approaches and medicines is important. In this review, we consider the probable mechanism of action of a traditional and ethnic formulary of chamomile extract in sesame oil as a new topical medication for migraine pain relief. Chamomile oil is prepared in Traditional Persian Medicine by boiling aqueous extract of chamomile in sesame oil. To optimize the procedure, we can use a Clevenger-type apparatus to extract the essential oil and add it to the end product. The preparation includes both essential oils (chamazulene and bisabolol oxide) and polyphenols (a flavonoid such as apigenin and its derivatives). It probably possesses pain relief effects for migraines because of the following properties: (1) chamazulene and apigenin, which inhibit iNOS expression in activated macrophages and can lead to the prohibition of NO release and synthesis; (2) chamomile flavonoids, which have a strong inhibitory effect on endogenous prostaglandin E2 (PGE2) levels in RAW 264.7 macrophages and can play the role of selective COX-2 inhibitor; (3) chamomile polyphenols, which possess anti-inflammatory effects due to the inhibition of pro-inflammatory biomarkers in THP1 macrophages and which can reduce inflammation in neurovascular units (NVU) at the site of migraine pain; (4) chamomile, which has neuroprotective effects because of reduced NO levels; (5) sesamine in sesame oil, which possesses an anti-inflammatory effect. These effects are supported by main pathophysiological theories of migraine such as neural and sensitization theories. Chamomile oil is a traditional formulation still used in Iran as an ethno-medicine. Because of the mentioned mechanisms of action, it can be hypothesized that chamomile oil is a novel medicine for the relief of migraine pain. Copyright © 2014 Elsevier Ltd. All rights reserved.

Sensory characteristics and cross-cultural consumer acceptability of Bulgogi (Korean traditional barbecued beef).

PubMed

Hong, J H; Yoon, E K; Chung, S J; Chung, L; Cha, S M; O'Mahony, M; Vickers, Z; Kim, K O

2011-01-01

Bulgogi (Korean traditional barbecued beef) is the most well-known Korean food to foreigners. There are, however, few studies on its sensory characteristics and consumer acceptability. This study was performed to identify the sensory attributes of Bulgogi samples prepared with different formulation and to compare the consumer acceptability in Korea and the United States. Bulgogi samples were prepared with varying levels of sugar and soy sauce with/without garlic or sesame oil. Descriptive analysis was conducted by 8 trained panelists. In consumer tests, 42 consumers in Seoul, Korea, 53 consumers in Davis (Calif., U.S.A.), and 39 consumers in St. Paul (Minn., U.S.A.) participated. Higher levels of sugar and soy sauce (SSS) significantly increased sweetness, saltiness, MSG taste, and soy sauce odor/flavor compared to the control made with the standard formula (CON). Elimination of sesame oil (ESO) significantly decreased sesame oil odor/flavor and oiliness, but increased green onion flavor. Elimination of garlic (EGC) significantly increased grilled beef odor/flavor, sesame oil odor/flavor, and oiliness, but decreased intensities of all the other attributes except bitterness. The consumers in Korea and the United States rated their overall liking for all samples similarly, preferring SSS to CON, EGC, and ESO. However Korean consumers seemed to detect the differences caused by formulation changes better than the U.S. consumers and these perceived differences seemed to impact the hedonic and the just-about-right ratings. Increase in soy sauce and sugar increased both Korean and the U.S. consumers' acceptability of Bulgogi, whereas eliminating garlic did not influence the consumer acceptability despite of its significant impact on sensory attributes. The food industry is increasingly interested in ethnic foods that satisfy sophisticated appetite of today's consumers. Korean cuisine is recently gaining popularity and perceived as "adventurous and spicy," appealing to researchers and marketers in the food industry worldwide. However, it is not easy to develop a new product based on ethnic cuisine because nonsensory factors, such as food neophobia and openness to new culture, can evoke adverse responses from the consumers. A systematic sensory approach can guide the product development by identifying both sensory and nonsensory factors affecting consumer acceptability. This study investigated sensory attributes of Bulgogi (Korean traditional barbecued beef), one of the most famous Korean foods, and compared consumer acceptability between Korea and the United States. The outcomes of this study, such as flavor profiles, consumer responses, evaluation procedure, and approaches taken for cross-cultural comparison, will provide the food industries with valuable information that will help to develop effective strategies for commercializing ethnic foods including recipe development for Bulgogi marinades. © 2011 Institute of Food Technologists®

The Global Expansion of Children's Television: A Case Study of the Adaptation of "Sesame Street" in Spain

ERIC Educational Resources Information Center

Moran, Kristin C.

2006-01-01

The landscape of children's programming is changing because of the increased exportation of children's television programs created in the USA. Networks have been aggressively marketing programs to an international audience through individual program sales and satellite network expansion. Some see problems as a result of the potential shift in…

The Participation of Our Schools in the Defense and Diffusion of National Culture

ERIC Educational Resources Information Center

Cassanova, Manuel Gonzales

1977-01-01

Recounts a paper presented to the 18th Congress of the Centre International De Liaison Des Ecoles De Cinema et Television (CILECT) in 1976. Contends that American interests are infiltrating countries which are unable to defend against such threats to their national identity and analyzes "Sesame Street" to illustrate this contention. (MH)

Infant Attention to Dynamic Audiovisual Stimuli: Look Duration from 3 to 9 Months of Age

ERIC Educational Resources Information Center

Reynolds, Greg D.; Zhang, Dantong; Guy, Maggie W.

2013-01-01

The goal of this study was to examine developmental change in visual attention to dynamic visual and audiovisual stimuli in 3-, 6-, and 9-month-old infants. Infant look duration was measured during exposure to dynamic geometric patterns and Sesame Street video clips under three different stimulus modality conditions: unimodal visual, synchronous…

Research study: STS-1 Orbiter Descent

NASA Technical Reports Server (NTRS)

Hickey, J. S.

1981-01-01

The conversion of STS-1 orbiter descent data from AVE-SESAME contact programs to the REEDA system and the reduction of raw radiosonde data is summarized. A first difference program, contact data program, plot data program, and 30 second data program were developed. Six radiosonde soundings were taken. An example of the outputs of each of the programs is presented.

Leveling up from Player to Designer: Engaging and Empowering Youth through Making Video Games

ERIC Educational Resources Information Center

Gershenfeld, Alan

2011-01-01

Over the past few years a growing body of research has highlighted the potential for educational video games to foster highly engaged, effective learning in the classroom. These research reports from organizations such as the Federation of American Scientists, the National Science Foundation, and the Joan Ganz Cooney Center at Sesame Workshop…

Building Up the Other Side of Sesame Street. Organizing and Administering Delivery of Off Campus Continuing Professional Education.

ERIC Educational Resources Information Center

Sarlos, Beatrice E.

Continuing professional education (CPE), defined as educational services offered to professionals (those who possess initial degrees required for practice) without the restrictions of traditional scheduling, credits, tuition, or instruction methods, is discussed. The importance of a uniform terminology to distinguish the specific area of CPE is…

How We Got to Sesame Street; Art on Screen

ERIC Educational Resources Information Center

Goldstein, Evan R.

2009-01-01

In 1966 a group of friends gathered for a dinner party in Manhattan. As the evening was winding down, one of the guests, Lloyd N. Morrisett, a vice president at the Carnegie Corporation, turned to his host, a television executive named Joan Ganz Cooney, and asked a seemingly innocuous question: Can television educate young children? Unknown to…

A Report on the Technological Enhancements Project Evaluation: Deepening Early Learning Experiences through Technology

ERIC Educational Resources Information Center

Hupert, Naomi; Cervantes, Francisco; DeGroof, Emily

2010-01-01

As part of the "Ready to Learn" Initiative, Education Development Center, Inc. (EDC), was charged with addressing the evaluation of Technological Enhancements for the outreach efforts of three producers: Out of the Blue's Super WHY! Technology Add-On; Sesame Workshop's The Electric Company School's Initiative Curriculum; and WordWorld's eBook…

Efficacy of some plant oils alone and/or combined with different insecticides on the cotton leaf-worm Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae) in Egypt.

PubMed

Mesbah, H A; Mourad, A K; Rokaia, A Z M

2006-01-01

The present work was conducted to evaluate the efficiency of two essential oils ((Flax or "Linseed" and Sesame ), five volatile plant oils ( Camphor, Red basil, Rose, Menthol and Clove ), four pesticides (Methoxyfenozide; Permethrin; Profenofos and Spinosad) and their mixtures on the cotton leaf-worm Spodoptera littoralis (Boisd.). This study was also devoted to minimize the usage of conventional insecticides, reduce the environmental pollution, and protect human-beings and domestic animals from hazards due to pesticides applications. In the meantime, the delayed effect of these tested plant oils on the developing immatures and moths of the cotton leaf-worm, Spodoptera littoralis was determined. Most of the evaluated plant oils were found to have an insecticidal effect on the 4th instar larvae of the cotton leaf-worm, S. littoralis. Both the essential Sesame oil and Clove volatile oil showed rather weak toxic effect corresponding to the same concentrations and periods of the bioassay tests. Comparing the toxicity of the tested plant oils, it was affirmed that both Rose and Red basil volatile oils were the highest efficient natural phytocompounds against the treated larvae and alternatively ranked either the 1st and/or the 2nd rank, throughout the different periods of the bioassay tests, followed by the other three tested oils which were more or less efficient phytocompounds. According to the toxicity index, all the tested oils were less toxic than the superior Red basil volatile oil after 48 h. post treatment followed by the gradual decrease in toxicity of Rose, Flax and Menthol, respectively. The development of the treated 4th larval instar was blocked due to treatment with the tested plant oils. With no exception, all the efficiently tested essential and/or volatile oils acted principally as Insect Growth Inhibitors (IGIs) rather than antifeedants causing disruption of the insect development, abnormal larvae, pupae and adults that were lead finally to death. The tested mixtures of Clove and Sesame oils increased the percentage of larval mortality in comparison to their use alone against the treated 4th larval instar.Contrarily, antagonism was revealed for the mixture of Sesame/Flax oils, the calculated value of LC50 greatly increased compared to the corresponding values of their individual evaluation after 48 h. from initiating the treatment. The delayed effect of tested plant oils was inspected on certain parameters of the fitness components of the subject insect and was mainly determined for the rates of hatched eggs and emerged moths. Remarkably, the Methoxyfenozide treated 4th larval instar became passive, or ceased feeding on the treated leaves and were unable to complete normally the moulting process, which partially took place in most'of the other treated individuals. The treated larvae with the tested lower concentrations, hardly succeeded in completing moulting process. The survived larvae failed to complete the next moulting at the end of the treatments. The toxic effect of Spinosad was more apparent against the treated larvae after 72 h from application. The calculated LC50 values indicated the gradual increase of its toxic effect in the subsequent prolonged intervals of the test. Spinosad showed its activity either by contact or ingestion and caused larval characteristic symptoms. Permethrin exhibited superior toxic efficacy overall the other tested chemicals, during the period from 72 up to 96 h post treatment. The gradual increase of the toxic effect of Permethrin indicated an efficient continuous persistence of nervous toxicity. According to the specific properties of Profenofos, results revealed that the toxicity by ingestion was more potential than by contact and explained the reason of developing toxicity with the increase of bioassay inspection period. The comparative toxic efficiency of the tested insecticides proved that Permethrin was the most effective one, giving LC50 values of 2.92 and 1.53 ppm after 72 and 96 h. bioassay, respectively, followed by Profenofos, Methoxyfenozide and Spinosad, successively. In addition, the calculated values of toxicity index also proved that all the tested compounds were less toxic than Permethrin (as a standard compound ). It is worth mentioning that the combined action of the mixed pesticides with four efficient volatile plant oils showed synergistic action against the 4th larval instar of S. littoralis.

High-throughput authentication of edible oils with benchtop Ultrafast 2D NMR.

PubMed

Gouilleux, B; Marchand, J; Charrier, B; Remaud, G S; Giraudeau, P

2018-04-01

We report the use of an Ultrafast 2D NMR approach applied on a benchtop NMR system (43 MHz) for the authentication of edible oils. Our results demonstrate that a profiling strategy based on fast 2D NMR spectra recorded in 2.4 min is more efficient than the standard 1D experiments to classify oils from different botanical origins, since 1D spectra on the same samples suffer from strong peak overlaps. Six edible oils with different botanical origins (olive, hazelnut, sesame, rapeseed, corn and sunflower) have been clearly discriminated by PCA analysis. Furthermore, we show how this approach combined with a PLS model can detect adulteration processes such as the addition of hazelnut oil into olive oil, a common fraud in food industry. Copyright © 2017 Elsevier Ltd. All rights reserved.

Kinetic energy budgets in areas of intense convection

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Berecek, E. M.; Ebel, D. M.; Jedlovec, G. J.

1980-01-01

A kinetic energy budget analysis of the AVE-SESAME 1 period which coincided with the deadly Red River Valley tornado outbreak is presented. Horizontal flux convergence was found to be the major kinetic energy source to the region, while cross contour destruction was the major sink. Kinetic energy transformations were dominated by processes related to strong jet intrusion into the severe storm area. A kinetic energy budget of the AVE 6 period also is presented. The effects of inherent rawinsonde data errors on widely used basic kinematic parameters, including velocity divergence, vorticity advection, and kinematic vertical motion are described. In addition, an error analysis was performed in terms of the kinetic energy budget equation. Results obtained from downward integration of the continuity equation to obtain kinematic values of vertical motion are described. This alternate procedure shows promising results in severe storm situations.

Occupational Portrayal of Men and Women on the Most Frequently Mentioned Television Shows of Preschool Children.

ERIC Educational Resources Information Center

Shechtman, Stephen A.

The purpose of this study was to assess the distribution of male vs. female occupational portrayals in terms of occupational prestige on the six television shows most frequently mentioned by preschool children. The following shows were viewed and analyzed six times: Sesame Street, Bugs Bunny, Roadrunner, Batman, Flintstones, and Happy Days.…

Adult-Child Co-Viewing of Educational Television: Enhancing Preschoolers' Understanding of Mathematics Shown on "Sesame Street"

ERIC Educational Resources Information Center

Morgenlander, Melissa

2010-01-01

Can adults help children to understand the content in preschool educational television by watching shows with them? Research indicates that co-viewing occurs rarely and has mixed benefits for learning. This study investigates the idea that a special kind of adult-child co-viewing, namely "dialogic viewing," in which adults ask open-ended questions…

Area Handbook Series: Thailand. A Country Study

DTIC Science & Technology

1987-09-01

cashew nuts , soybeans, bananas, sesame, coco- nuts , cotton, kapok, and castor beans. Rice Rice, the nation’s major crop, was grown by about three...Sugarcane ......... 5,382.0 6,585.9 19,910.0 30,260.0 24,000.0 24,410.0 Mung beans ........ 60.3 150.5 120.6 283.7 323.4 325.0 Ground nuts ....... 152.0

Digital Learners: How Are They Expanding the Horizon of Learning?

ERIC Educational Resources Information Center

Jackson, Sherion H.; Crawford, Debi

2008-01-01

Young learners today are not growing up at the foot of the family radio or spending a good portion of their childhood glued to the television while Sesame Street and Mr. Rogers disseminate information in a constant stream as did previous generations. Rather, this generation of young learners continues to spend many out-of-school hours in a digital…

Today's Program Is Brought to You by the Letters--Debit and Credit and by the Number Income

ERIC Educational Resources Information Center

Bush, H. Francis; Walsh, Vonda K.

2011-01-01

As each generation comes of age they receive a label. Currently, we are teaching the new millennials. Their learning style and time management preferences may respond better to a constant task and feedback cycle similar to the popular Public Television Series, Sesame Street. This paper examines the effects of requiring students to take an…

STEM Starts Early: Grounding Science, Technology, Engineering, and Math Education in Early Childhood

ERIC Educational Resources Information Center

McClure, Elisabeth R.; Guernsey, Lisa; Clements, Douglas H.; Bales, Susan Nall; Nichols, Jennifer; Kendall-Taylor, Nat; Levine, Michael H.

2017-01-01

Tomorrow's inventors and scientists are today's curious young children--as long as those children are given ample chances to explore and are guided by adults equipped to support them. "STEM Starts Early" is the culmination of a deep inquiry by the Joan Ganz Cooney Center at Sesame Workshop and New America embarked on an exploratory…

STEM Starts Early: Grounding Science, Technology, Engineering, and Math Education in Early Childhood. Executive Summary

ERIC Educational Resources Information Center

McClure, Elisabeth R.; Guernsey, Lisa; Clements, Douglas H.; Bales, Susan Nall; Nichols, Jennifer; Kendall-Taylor, Nat; Levine, Michael H.

2017-01-01

Tomorrow's inventors and scientists are today's curious young children--as long as those children are given ample chances to explore and are guided by adults equipped to support them. "STEM Starts Early" is the culmination of a deep inquiry by the Joan Ganz Cooney Center at Sesame Workshop and New America embarked on an exploratory…

Infants' Attention to Patterned Stimuli: Developmental Change from 3 to 12 Months of Age

ERIC Educational Resources Information Center

Courage, Mary L.; Reynolds, Greg D.; Richards, John E.

2006-01-01

To examine the development of look duration as a function of age and stimulus type, 14- to 52-week-old infants were shown static and dynamic versions of faces, Sesame Street material, and achromatic patterns for 20 s of accumulated looking. Heart rate was recorded during looking and parsed into stimulus orienting, sustained attention, and…

Video Songs from "Sesame Street": A Comparison of Fifth Graders' and Adults' Opinions Regarding Messages for Preschool Children.

ERIC Educational Resources Information Center

Jellison, Judith A.; Wolfe, David E.

1999-01-01

Assesses the opinions of fifth graders and adults concerning messages conveyed to preschool children through video songs. Compares their responses to questions about the same video. Solicits opinions regarding the importance of the messages, whether they would be learned, and how well they would be liked by preschool children. (DSK)

Experimental Research in TV Instruction. Proceedings of an International Conference (5th, St. John's, Newfoundland, June 28-30, 1982). Volume 5.

ERIC Educational Resources Information Center

Baggaley, Jon, Ed.; Janega, Patti, Ed.

An introduction briefly summarizes the four previous conferences in this series, identifies trends in topics addressed, and introduces the 16 presented papers in this collection. The papers are as follows: (1) "Formative Evaluation and the New Technologies" (Marjorie Cambre); (2) "Formative Evaluation of Sesame Street Using Eye…

Comparison of solid-phase cytometry and the plate count method for the evaluation of the survival of bacteria in pharmaceutical oils.

PubMed

De Prijck, K; Peeters, E; Nelis, H J

2008-12-01

To compare the survival of four bacterial strains (Escherichia coli, Proteus mirabilis, Staphylococcus aureus, Pseudomonas aeruginosa) in pharmaceutical oils, including jojoba oil/tea tree oil, carbol oil, jojoba oil and sesame oil. Oils were spiked with the test bacteria in a concentration of 10(4) CFU ml(-1). Bacteria were extracted from oils with phosphate-buffered saline containing 0.5% Tween 20. Aliquots of the pooled water layers were analysed by solid-phase cytometry and plate counting. Plate counts dropped to zero for all test strains exposed for 24 h to three of the four oils. In contrast, significant numbers of viable cells were still detected by SPC, except in the jojoba oil/tea tree oil mixture and partly in sesame oil. Exposure of bacteria for 24 h to the two oils containing an antimicrobial led to a loss of their culturability but not necessarily of their viability. The antibacterial activity of the jojoba oil/tea tree oil mixture supersedes that of carbol oil. These in vitro data suggest that the jojoba oil/tea tree oil mixture more than carbol oil inhibits bacterial proliferation when used for intermittent self-catherization.

Formulation and Characterization of Benzoyl Peroxide Gellified Emulsions

PubMed Central

Thakur, Naresh Kumar; Bharti, Pratibha; Mahant, Sheefali; Rao, Rekha

2012-01-01

The present investigation was carried out with the objective of formulating a gellified emulsion of benzoyl peroxide, an anti-acne agent. The formulations were prepared using four different vegetable oils, viz. almond oil, jojoba oil, sesame oil, and wheat germ oil, owing to their emollient properties. The idea was to overcome the skin irritation and dryness caused by benzoyl peroxide, making the formulation more tolerable. The gellified emulsions were characterized for their homogeneity, rheology, spreadability, drug content, and stability. In vitro permeation studies were performed to check the drug permeation through rat skin. The formulations were evaluated for their antimicrobial activity, as well as their acute skin irritation potential. The results were compared with those obtained for the marketed formulation. Later, the histopathological examination of the skin treated with various formulations was carried out. Formulation F3 was found to have caused a very mild dysplastic change to the epidermis. On the other hand, the marketed formulation led to the greatest dysplastic change. Hence, it was concluded that formulation F3, containing sesame oil (6%w/w), was the optimized formulation. It exhibited the maximum drug release and anti-microbial activity, in addition to the least skin irritation potential. PMID:23264949

Spectrum response estimation for deep-water floating platforms via retardation function representation

NASA Astrophysics Data System (ADS)

Liu, Fushun; Liu, Chengcheng; Chen, Jiefeng; Wang, Bin

2017-08-01

The key concept of spectrum response estimation with commercial software, such as the SESAM software tool, typically includes two main steps: finding a suitable loading spectrum and computing the response amplitude operators (RAOs) subjected to a frequency-specified wave component. In this paper, we propose a nontraditional spectrum response estimation method that uses a numerical representation of the retardation functions. Based on estimated added mass and damping matrices of the structure, we decompose and replace the convolution terms with a series of poles and corresponding residues in the Laplace domain. Then, we estimate the power density corresponding to each frequency component using the improved periodogram method. The advantage of this approach is that the frequency-dependent motion equations in the time domain can be transformed into the Laplace domain without requiring Laplace-domain expressions for the added mass and damping. To validate the proposed method, we use a numerical semi-submerged pontoon from the SESAM. The numerical results show that the responses of the proposed method match well with those obtained from the traditional method. Furthermore, the estimated spectrum also matches well, which indicates its potential application to deep-water floating structures.

Density-Functional-Theory-Based Equation-of-State Table of Beryllium for Inertial Confinement Fusion Applications

NASA Astrophysics Data System (ADS)

Ding, Y. H.; Hu, S. X.

2017-10-01

Beryllium has been considered a superior ablator material for inertial confinement fusion target designs. Based on density-functional-theory calculations, we have established a wide-range beryllium equation-of-state (EOS) table of density ρ = 0.001 to ρ = 500 g/cm3 and temperature T = 2000 to 108 K. Our first-principles equation-of-state (FPEOS) table is in better agreement with widely used SESAMEEOS table (SESAME2023) than the average-atom INFERNOmodel and the Purgatoriomodel. For the principal Hugoniot, our FPEOS prediction shows 10% stiffer behavior than the last two models at maximum compression. Comparisons between FPEOS and SESAMEfor off-Hugoniot conditions show that both the pressure and internal energy differences are within 20% between two EOS tables. By implementing the FPEOS table into the 1-D radiation-hydrodynamics code LILAC, we studied the EOS effects on beryllium target-shell implosions. The FPEOS simulation predicts up to an 15% higher neutron yield compared to the simulation using the SESAME2023 EOS table. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944.

Threshold Dynamics of a Semiconductor Single Atom Maser

NASA Astrophysics Data System (ADS)

Liu, Yinyu

Photon emission from single emitters provides fundamental insight into the detailed interaction between light and matter. Here we demonstrate a semiconductor single atom maser (SeSAM) that consists of a single InAs double quantum dot (DQD) that is coupled to a high quality factor microwave cavity. A finite bias results in population inversion in the DQD, enabling sizable cavity gain and stimulated emission. We develop a pulsed-gate approach that allows the SeSAM to be tuned across the masing threshold. The cavity output power as a function of DQD current is in good agreement with single atom maser theory once a small correction for lead emission is included. Photon statistics measurements show that the second-order correlation function of intra-cavity photon number, nc, crosses over from 〈nc2 〉 /〈nc 〉 2 = 2.1 below threshold to 〈nc2 〉 /〈nc 〉 2 = 1.2 above threshold. Large fluctuations are observed at threshold. In collaboration with J. Stehlik, C. Eichler, X. Mi, T. R. Hartke, M. J. Gullans, J. M. Taylor and J. R. Petta. Supported by the NSF and the Gordon and Betty Moore Foundation's EPiQS initiative through Grant No. GBMF4535.

Enhancing Understanding of Magnetized High Energy Density Plasmas from Solid Liner Implosions Using Fluid Modeling with Kinetic Closures

NASA Astrophysics Data System (ADS)

Masti, Robert; Srinivasan, Bhuvana; King, Jacob; Stoltz, Peter; Hansen, David; Held, Eric

2017-10-01

Recent results from experiments and simulations of magnetically driven pulsed power liners have explored the role of early-time electrothermal instability in the evolution of the MRT (magneto-Rayleigh-Taylor) instability. Understanding the development of these instabilities can lead to potential stabilization mechanisms; thereby providing a significant role in the success of fusion concepts such as MagLIF (Magnetized Liner Inertial Fusion). For MagLIF the MRT instability is the most detrimental instability toward achieving fusion energy production. Experiments of high-energy density plasmas from wire-array implosions have shown the requirement for more advanced physics modeling than that of ideal magnetohydrodynamics. The overall focus of this project is on using a multi-fluid extended-MHD model with kinetic closures for thermal conductivity, resistivity, and viscosity. The extended-MHD model has been updated to include the SESAME equation-of-state tables and numerical benchmarks with this implementation will be presented. Simulations of MRT growth and evolution for MagLIF-relevant parameters will be presented using this extended-MHD model with the SESAME equation-of-state tables. This work is supported by the Department of Energy Office of Science under Grant Number DE-SC0016515.

Estrogen levels modify scopolamine-induced amnesia in gonadally intact rats.

PubMed

de Macêdo Medeiros, André; Izídio, Geison Souza; Sousa, Diego Silveira; Macedo, Priscila Tavares; Silva, Anatildes Feitosa; Shiramizu, Victor Kenji Medeiros; Cabral, Alicia; Ribeiro, Alessandra Mussi; Silva, Regina Helena

2014-08-04

Previous studies suggested that estrogen plays a role in cognitive function by modulating the cholinergic transmission. However, most of the studies dealing with this subject have been conducted using ovariectomized rats. In the present study we evaluated the effects of physiological and supra-physiological variation of estrogen levels on scopolamine-induced amnesia in gonadally intact female rats. We used the plus-maze discriminative avoidance task (PMDAT) in order to evaluate anxiety levels and motor activity concomitantly to the memory performance. In experiment 1, female Wistar rats in each estrous cycle phase received scopolamine (1 mg/kg) or saline i.p. 20 min before the training session in the PMDAT. In experiment 2, rats in diestrus received estradiol valerate (1 mg/kg) or sesame oil i.m., and scopolamine (1 mg/kg) or saline i.p., 45 min and 20 min before the training, respectively. In experiment 3, rats in diestrus received scopolamine (1 mg/kg) or saline i.p. 20 min before the training, and estradiol valerate (1 mg/kg) or sesame oil i.m. immediately after the training session. In all experiments, a test session was performed 24 h later. The main results showed that: (1) scopolamine impaired retrieval and induced anxiolytic and hyperlocomotor effects in all experiments; (2) this cholinergic antagonist impaired acquisition only in animals in diestrus; (3) acute administration of estradiol valerate prevented the learning impairment induced by scopolamine and (4) interfered with memory consolidation process. The results suggest that endogenous variations in estrogen levels across the estrous cycle modulate some aspects of memory mediated by the cholinergic system. Indeed, specifically in diestrus, a stage with low estrogen levels, the impairment produced by scopolamine on the acquisition was counteracted by exogenous administration of the hormone, whereas the posttraining treatment potentiated the negative effects of scopolamine during the consolidation phase of memory. Copyright © 2014 Elsevier Inc. All rights reserved.

Plasma properties at 67P/Churyumov-Gerasimenko: a comparision between PP-SESAME/Philae/Rosetta and RPC/MIP/Rosetta

NASA Astrophysics Data System (ADS)

Schmidt, Walter; Henri, Pierre; Lebreton, Jean Pierre; Vallières, Xavier; Grard, Réjean; Hamelin, Michel; Le Gall, Alice; Lethuillier, Anthony; Ciarletti, Valerie; Caujolle-Bert, Sylvain; Seidensticker, Klaus; Fischer, Hans-Herbert

2016-04-01

On November 12, 2014, the Rosetta landing module Philae approached the nucleus of 67P/Churyumov-Gerasimenko and eventually settled on the surface in a location named Abydos, though its exact coordinates are still unknown. The Permittivity Probe (PP) as part of the SESAME (Surface Electric Sounding and Acoustic Monitoring Experiment) instrument package [1] was designed to not only measure the electrical properties of the comet's surface material by actively injecting an alternating current at different frequencies into the material underneath the Lander but also to monitor potential variations between its two receivers and the electrical conductivity of the plasma environment while still in space. By sampling the potential difference at 40 kHz between the soles of two of the feet attached to Philae's landing gear, plasma waves between 20 and 20 000 Hz should be detectable if their amplitudes are large enough. The injection of low frequency currents into the plasma environment during Philae's descent gives indications for changes of the plasma density when approaching the comet. In this paper we present observations from the cross-calibration campaign with the Rosetta plasma package instrument MIP (Mutual Impedance Probe) [2] during the Pre-Delivery Calibration and Science (PDCS) operations on October 17, 2014, during the descent towards the comet surface on November 12, 2014, and from the First Science Sequence at Abydos on November 13. During the PDCS campaign most PP observation slots coincided with plasma waves dominantly in the 100 to 150 kHz range according to MIP measurements. Accordingly PP did not register any signals. Only in the afternoon of the 17th low frequency waves were recorded by MIP. At the same time the measured PP wave power signal was above the background for frequencies below 500 Hz in several subsequent measurements. During the descent [3] the injected current at 758 Hz dropped suddenly by about 5 % possibly indicating a decrease in the plasma density at an altitude of about 18.5 km above the comet surface. During the First Science Sequence PP was monitoring low frequency wave-like activities starting two hours after local sunset. References: [1] K. J. Seidensticker, H-H. Fischer, D. Medlener, S. Schieke, K. Thiel, A. Peter, W. Schmidt and R. Trautner, 2004: The Rosetta lander experiment sesame and the new target comet 67P/Churyumov-Gerasimenko. The New ROSETTA Targets - Observations, Simulations and Instrument Performances, Astrophys. Space Sci. 311, 297-307 [2] J. G. Trotignon et al., RPC-MIP: the Mutual Impedance Probe of the Rosetta Plasma Consortium, Space Science Reviews, February 2007, Volume 128, Issue 1, pp 713-728 [3] H.Krüger et al., Dust Impact Monitor (SESAME-DIM) Measurements at Comet 67P/Churyumov-Gerasimenko, Astronomy&Astrophysics, Volume 583, November 2015, DOI http://dx.doi.org/10.1051/0004-6361/201526400

Investigations of severe/tornadic thunderstorm development and evolution based on satellite and AVE/SESAME/VAS data

NASA Technical Reports Server (NTRS)

Vonderhaar, T. H.; Purdom, J. F. W.

1984-01-01

The use of rapid scan satellite imagery to investigate the local environment of severe thunderstorms is discussed. Mesoscale cloud tracking and vertical wind shear as it affects thunderstorm relative flow are mentioned. The role of pre-existing low level cloud cover in the outbreak of tornadoes was investigated. Applying visible atmospheric sounding imagery to mesoscale phenomena is also addressed.

A New Multiphase Equation of State for Composition B

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coe, Joshua Damon; Margevicius, Madeline Alma

2016-07-25

We describe the construction of a complete equation of state for the high explosive Composition B in its unreacted (inert) form, as well as chemical equilibrium calculations of its detonation products. The multiphase reactant EOS is of SESAME type, and was calibrated to ambient thermal and mechanical data, the shock initiation experiments of Dattelbaum, et al., and the melt line of trinitrotoluene (TNT).

Southeast Asia Report.

DTIC Science & Technology

1985-08-22

yielding.14,140 tons of nuts , mostly for export. Furthermore, the province planted nearly 1,000 new hectares of rubber while exploiting 6,000 hectares...and sesame. The areas under pineapple, banana, cashew , onion, and garlic will also be expanded. Piq, duck and goose raising has been developed in...acacia auriculiformis), etc. The water-craving area of Thuan Hai Province can accomodate fir trees, cam xe (sylia dolabriform is), cashew , and

Former Astronaut Leland Melvin speaks with Elmo

NASA Image and Video Library

2011-07-06

NASA Associate Administrator for Education and former astronaut Leland Melvin teaches the ABC's of living and working in space to Sesame Street's Elmo at NASA's Kennedy Space Center, Wednesday, July 6, 2011 in Cape Canaveral, FL. The pair discussed nutrition, exercise, hygiene in orbit. They also chatted about the features of the space shuttle and the various suits that astronauts wear. Photo Credit: (NASA/Carla Cioffi)

"The Tower in Red and Yellow": Using Children's Drawings in Formative Research for "Alam Simsim," an Educational Television Series for Egyptian Children.

ERIC Educational Resources Information Center

Montasser, Alyaa; Cole, Charlotte; Fuld, Janice

2002-01-01

Provides examples from a study of six test segments of the television series "Alam Simsim," the Egyptian "Sesame Street," to illustrate how a systematic analysis of children's artwork can be used with other research tools to gain feedback from children. Shows how formative research is used to bring children into the production…

Preparing Minority Populations for Emergencies: Connecting to Build a More Resilient Community

DTIC Science & Technology

2012-12-01

the 172 Philip Berke et al., “Building Capacity for Disaster Resiliency in Six Disadvantaged...the Poor and Underserved 18 (2007): 277–282. Berke, Philip , John Cooper, David Salvesen, Danielle Spurlock, and Christina Rausch. “Building...Takeuchi, and Jennifer Kotler . Always Connected: The New Digital Media Habits of Young Children. New York: The Joan Ganz Cooney Center at Sesame

Skin prick test responses and allergen-specific IgE levels as predictors of peanut, egg, and sesame allergy in infants.

PubMed

Peters, Rachel L; Allen, Katrina J; Dharmage, Shyamali C; Tang, Mimi L K; Koplin, Jennifer J; Ponsonby, Anne-Louise; Lowe, Adrian J; Hill, David; Gurrin, Lyle C

2013-10-01

Ninety-five percent positive predictive values (PPVs) provide an invaluable tool for clinicians to avoid unnecessary oral food challenges. However, 95% PPVs specific to infants, the age group most likely to present for diagnosis of food allergy, are limited. We sought to develop skin prick test (SPT) and allergen-specific IgE (sIgE) thresholds with 95% PPVs for challenge-confirmed food allergy in a large population-based cohort of 1-year-old infants with challenges undertaken irrespective of SPT wheal size or previous history of ingestion. HealthNuts is a population-based, longitudinal food allergy study with baseline recruitment of 1-year-old infants. Infants were recruited from council-run immunization sessions during which they underwent SPTs to 4 allergens: egg, peanut, sesame, and cow's milk/shrimp. Any infant with a detectable SPT response was invited to undergo oral food challenge and sIgE testing. Five thousand two hundred seventy-six infants participated in the study. Peanut SPT responses of 8 mm or greater (95% CI, 7-9 mm), egg SPT responses of 4 mm or greater (95% CI, 3-5 mm), and sesame SPT responses of 8 mm or greater (95% CI, 5-9 mm) had 95% PPVs for challenge-proved food allergy. Peanut sIgE levels of 34 kUA/L or greater (95% CI, 14-48 kUA/L) and egg sIgE levels of 1.7 kUA/L or greater (95% CI, 1-3 kUA/L) had 95% PPVs for challenge-proved food allergy. Results were robust when stratified on established risk factors for food allergy. Egg SPT responses and sIgE levels were poor predictors of allergy to egg in baked goods. These 95% PPVs, which were generated from a unique dataset, are valuable for the diagnosis of food allergy in young infants and were robust when stratified across a number of different risk factors. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

Simulation Enabled Safeguards Assessment Methodology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert Bean; Trond Bjornard; Thomas Larson

2007-09-01

It is expected that nuclear energy will be a significant component of future supplies. New facilities, operating under a strengthened international nonproliferation regime will be needed. There is good reason to believe virtual engineering applied to the facility design, as well as to the safeguards system design will reduce total project cost and improve efficiency in the design cycle. Simulation Enabled Safeguards Assessment MEthodology (SESAME) has been developed as a software package to provide this capability for nuclear reprocessing facilities. The software architecture is specifically designed for distributed computing, collaborative design efforts, and modular construction to allow step improvements inmore » functionality. Drag and drop wireframe construction allows the user to select the desired components from a component warehouse, render the system for 3D visualization, and, linked to a set of physics libraries and/or computational codes, conduct process evaluations of the system they have designed.« less

Wind impact on the Black Sea ecosystem

NASA Astrophysics Data System (ADS)

Stanichny, Sergey; Ratner, Yuriy; Shokurov, Mike; Stanychna, Rimma; Soloviev, Dmytro; Burdyugov, Vyacheslav

2010-05-01

Combination of the recent satellite and meteorological data for the regional investigation allowed to describe new features of the processes in marine ecosystem and detect some relations with wind variability for different time scales. Next topics are highlighted in presentation: 1. Inter-annual variability of the wind stress curl over the Black Sea. Shift in the atmospheric processes after 2003 year and related variations in chlorophyll concentration and intensity of the mesoscale currents. 2. Like-tropical cyclone in September 2005 and its impact o the Black Sea upper layer. 3. Strong storm November 11, 2007 and oil pollutions of the Kerch Strait. 4. Relation of the Danube waters transport with wind fields for summer 2007 and 2008. 5. "Valley" wind in the Eastern part of the Black Sea and its impact on the Rim current formation. 6. Low wind conditions and blue -green algae bloom. NCEP, SKIRON and MHI MM5 wind data together with AVHRR, MODIS, MERIS, ETM+, QuikSCAT, ASAR (ESA) satellite data were used for investigation. Work was done with support of the SESAME FP7, "Stable Ecosystem" and Operational Oceanography NASU projects.

The Effect of Teachers' Professional Development in Video Technology on Mathematics and the English Language Learning of Preschoolers in a Rural Primary School in Pakistan

ERIC Educational Resources Information Center

Ikram, Hamid

2016-01-01

The purpose of this mixed methods study was to examine the effect of teachers' professional development in video technology (PBS & Sesame Street videos) on mathematics and the English language learning among nursery students in the rural area of Pakistan where it was impossible for students to experience watching videos for learning purposes.…

Pequi leaves incorporated into the soil reduce the initial growth of cultivated, invasive and native species.

PubMed

Allem, Laísa N; Gomes, Anabele S; Borghetti, Fabian

2014-10-21

Studies have identified the phytotoxicity of many native species of the Cerrado; however, most of them were conducted either in inert substrates, or using exaggerate proportions of plant material. We investigated the phytotoxicity of pequi leaves added to substrate soil in quantities compatible with the litter produced by this species. Pequi leaves were triturated and added to red latosol in concentrations of 0.75%, 1.5% and 3%; the control was constituted of leafless soil. These mixtures were added to pots and irrigated daily to keep them moist. Germinated seeds of the cultivated sorghum and sesame, of the invasive brachiaria and of the native purple ipê, were disposed in the pots to grow for five to seven days at 30°C within a photoperiod of 12 h. Seedlings of all the species presented a reduction in their initial growth in a dose-dependent way. In general, the root growth was more affected by the treatments than the shoot growth; moreover, signs of necrosis were observed in the roots of the sorghum, sesame and brachiaria. The phytotoxic effects generated by relatively small quantities of leaves, in a reasonable range of species within a soil substrate, suggest potential allelopathy of pequi leaves under natural conditions.

Pequi leaves incorporated into the soil reduce the initial growth of cultivated, invasive and native species.

PubMed

Allem, Laísa N; Gomes, Anabele S; Borghetti, Fabian

2014-12-01

Studies have identified the phytotoxicity of many native species of the Cerrado; however, most of them were conducted either in inert substrates, or using exaggerate proportions of plant material. We investigated the phytotoxicity of pequi leaves added to substrate soil in quantities compatible with the litter produced by this species. Pequi leaves were triturated and added to red latosol in concentrations of 0.75%, 1.5% and 3%; the control was constituted of leafless soil. These mixtures were added to pots and irrigated daily to keep them moist. Germinated seeds of the cultivated sorghum and sesame, of the invasive brachiaria and of the native purple ipê, were disposed in the pots to grow for five to seven days at 30°C within a photoperiod of 12 h. Seedlings of all the species presented a reduction in their initial growth in a dose-dependent way. In general, the root growth was more affected by the treatments than the shoot growth; moreover, signs of necrosis were observed in the roots of the sorghum, sesame and brachiaria. The phytotoxic effects generated by relatively small quantities of leaves, in a reasonable range of species within a soil substrate, suggest potential allelopathy of pequi leaves under natural conditions.

A green ultrasonic-assisted liquid-liquid microextraction based on deep eutectic solvent for the HPLC-UV determination of ferulic, caffeic and cinnamic acid from olive, almond, sesame and cinnamon oil.

PubMed

Khezeli, Tahere; Daneshfar, Ali; Sahraei, Reza

2016-04-01

A simple, inexpensive and sensitive ultrasonic-assisted liquid-liquid microextraction method based on deep eutectic solvent (UALLME-DES) was used for the extraction of three phenolic acids (ferulic, caffeic and cinnamic) from vegetable oils. In a typical experiment, deep eutectic solvent as green extraction solvent was added to n-hexane (as a typical oil medium) containing target analytes. Subsequently, the extraction was accelerated by sonication. After the extraction, phase separation (DES rich phase/n-hexane phase) was performed by centrifugation. DES rich phase (lower phase) was withdrawn by a micro-syringe and submitted to isocratic reverse-phase HPLC with UV detection. Under optimum conditions obtained by response surface methodology (RSM) and desirability function (DF), the method has good linear calibration ranges (between 1.30 and 1000 µg L(-1)), coefficients of determination (r(2)>0.9949) and low limits of detection (between 0.39 and 0.63 µg L(-1)). This procedure was successfully applied to the determination of target analytes in olive, almond, sesame and cinnamon oil samples. The relative mean recoveries ranged from 94.7% to 104.6%. Copyright © 2015 Elsevier B.V. All rights reserved.

Integrated approach for disease management and growth enhancement of Sesamum indicum L. utilizing Azotobacter chroococcum TRA2 and chemical fertilizer.

PubMed

Maheshwari, D K; Dubey, R C; Aeron, Abhinav; Kumar, Bhavesh; Kumar, Sandeep; Tewari, Sakshi; Arora, Naveen Kumar

2012-10-01

Azotobacter chroococcum TRA2, an isolate of wheat rhizosphere displayed plant growth promoting attributes including indole acetic acid, HCN, siderophore production, solubilization of inorganic phosphate and fixation of atmospheric nitrogen. In addition, it showed strong antagonistic effect against Macrophomina phaseolina and Fusarium oxysporum. It also caused degradation and digestion of cell wall components, resulting in hyphal perforations, empty cell (halo) formation, shrinking and lysis of fungal mycelia along with significant degeneration of conidia. Fertilizer adaptive variant strain of A. chroococcum TRA2 was studied with Tn5 induced streptomycin resistant transconjugants of wild type tetracycline-resistant TRA2 (designated TRA2(tetra+strep+)) after different durations. The strain was significantly competent in rhizosphere, as its population increased by 15.29 % in rhizosphere of Sesamum indicum. Seed bacterization with the strain TRA2 resulted in significant increase in vegetative growth parameters and yield of sesame over the non-bacterized seeds. However, application of TRA2 with half dose of fertilizers showed sesame yield almost similar to that obtained by full dose treatment. Moreover, the oil yield increased by 24.20 %, while protein yield increased by 35.92 % in treatment receiving half dose of fertilizer along with TRA2 bacterized seeds, as compared to untreated control.

KSC-2011-5096

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5091

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Doug Wheelock talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5099

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5093

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5100

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5094

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Doug Wheelock talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5089

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5092

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5098

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronaut Mike Massimino talks with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

Bee pollination increases yield quantity and quality of cash crops in Burkina Faso, West Africa.

PubMed

Stein, Katharina; Coulibaly, Drissa; Stenchly, Kathrin; Goetze, Dethardt; Porembski, Stefan; Lindner, André; Konaté, Souleymane; Linsenmair, Eduard K

2017-12-18

Mutualistic biotic interactions as among flowering plants and their animal pollinators are a key component of biodiversity. Pollination, especially by insects, is a key element in ecosystem functioning, and hence constitutes an ecosystem service of global importance. Not only sexual reproduction of plants is ensured, but also yields are stabilized and genetic variability of crops is maintained, counteracting inbreeding depression and facilitating system resilience. While experiencing rapid environmental change, there is an increased demand for food and income security, especially in sub-Saharan communities, which are highly dependent on small scale agriculture. By combining exclusion experiments, pollinator surveys and field manipulations, this study for the first time quantifies the contribution of bee pollinators to smallholders' production of the major cash crops, cotton and sesame, in Burkina Faso. Pollination by honeybees and wild bees significantly increased yield quantity and quality on average up to 62%, while exclusion of pollinators caused an average yield gap of 37% in cotton and 59% in sesame. Self-pollination revealed inbreeding depression effects on fruit set and low germination rates in the F1-generation. Our results highlight potential negative consequences of any pollinator decline, provoking risks to agriculture and compromising crop yields in sub-Saharan West Africa.

Comparison of three types of oil crop rotation systems for effective use and remediation of heavy metal contaminated agricultural soil.

PubMed

Yang, Yang; Zhou, Xihong; Tie, Boqing; Peng, Liang; Li, Hongliang; Wang, Kelin; Zeng, Qingru

2017-12-01

Selecting suitable plants tolerant to heavy metals and producing products of economic value may be a key factor in promoting the practical application of phytoremediation polluted soils. The aim of this study is to further understand the utilization and remediation of seriously contaminated agricultural soil. In a one-year field experiment, we grew oilseed rape over the winter and then subsequently sunflowers, peanuts and sesame after the first harvest. This three rotation system produced high yields of dry biomass; the oilseed rape-sunflower, oilseed rape-peanut and oilseed rape-sesame rotation allowed us to extract 458.6, 285.7, and 134.5 g ha -1 of cadmium, and 1264.7, 1006.1, and 831.1 g ha -1 of lead from soil, respectively. The oilseed rape-sunflower rotation showed the highest phytoextraction efficiency (1.98%) for cadmium. Lead and cadmium in oils are consistent with standards after extraction with n-hexane. Following successive extractions with potassium tartrate, concentrations of lead and cadmium in oilseed rape and peanut seed meals were lower than levels currently permissible for feeds. Thus, this rotation system could be useful for local farmers as it would enable the generation of income during otherwise sparse phytoremediation periods. Copyright © 2017. Published by Elsevier Ltd.

Evaluation of Wound Healing Properties of Grape Seed, Sesame, and Fenugreek Oils

PubMed Central

Ksouda Moalla, Kamilia; Kammoun, Naziha Grati; Rebai, Tarek; Sahnoun, Zouheir

2016-01-01

Background. Medicinal plants have proved at all times to be a powerful remedy for health care. Accordingly, grape seed, sesame, and fenugreek extracted oils with pharmacological properties are investigated as wound treatments. This study assesses the potential of our oils for healing wounds induced on rats. Methods. Phytochemical analyses of oils have involved: quality value, polyphenol, chlorophylls, carotene, and fatty acids. Antibacterial activity was carried out. Antioxidant activity was evaluated: the scavenging effect on DPPH radicals, the reducing power, and β-carotene discoloration. Uniform wound excision was induced on rats dorsum randomly divided into five groups: groups treated with “CICAFLORA®” and tested oils and untreated one. The posthealing biopsies were histologically assessed. Results. Wound biopsies treated with oils showed the best tissue regeneration compared to control groups. Groups treated with our oils and “CICAFLORA” had higher wound contraction percentage. Polyunsaturated fatty acids in oils act as inflammatory mediators increasing neovascularization, extracellular remodeling, migration, and cell differentiation. Wound healing effect was attributed to antibacterial and antioxidant synergy. Conclusion. According to findings, oils showed better activity in wound healing compared to “CICAFLORA” due to a phytoconstituents synergy. However, clinical trials on humans are necessary to confirm efficacy on human pathology. PMID:27990170

Synchrotron Light Sources in Developing Countries

NASA Astrophysics Data System (ADS)

Winick, Herman; Pianetta, Piero

2017-01-01

The more than 50 light sources now in operation around the world include facilities in Brazil, Korea, and Taiwan which started their programs in the 1980's when they were developing countries. They came on line in the 1990's and have since trained hundreds of graduate students locally, without sending them abroad and losing many of them. They have also attracted dozens of mid-career diaspora scientists to return. Their growing user communities have demanded more advanced facilities, leading to the funding of higher performance new light sources that are now coming into operation. Light sources in the developing world now include the following: SESAME in the Middle East which is scheduled to start research in 2017 (www.sesame.org); The African Light Source, in the planning stage (www.africanlightsource.org); and The Mexican Light Source, in the planning stage (http://www.aps.org/units/fip/newsletters/201509/mexico.cfm). See: http://wpj.sagepub.com/content/32/4/92.full.pdf +html; http://www.lightsources.org/press-release/2015/11/20/grenoble-resolutions-mark-historical-step-towards-african-light-source. SLAC National Accelerator Laboratory, is supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Contract No. DE-AC02-76SF00515.

Synergistic ameliorative effects of sesame oil and alpha-lipoic acid against subacute diazinon toxicity in rats: hematological, biochemical, and antioxidant studies.

PubMed

Abdel-Daim, Mohamed M; Taha, Ramadan; Ghazy, Emad W; El-Sayed, Yasser S

2016-01-01

Diazinon (DZN) is a common organophosphorus insecticide extensively used for agriculture and veterinary purposes. DZN toxicity is not limited to insects; it also induces harmful effects in mammals and birds. Our experiment evaluated the protective and antioxidant potential of sesame oil (SO) and (or) alpha-lipoic acid (ALA) against DZN toxicity in male Wistar albino rats. DZN-treated animals exhibited macrocytic hypochromic anemia and significant increases in serum biochemical parameters related to liver injury, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), γ-glutamyl transferase (γGT), cholesterol, and triglycerides. They also had elevated levels of markers related to cardiac injury, such as lactate dehydrogenase (LDH) and creatine phosphokinase (CPK), and increased biomarkers of renal injury, urea and creatinine. DZN also increased hepatic, renal, and cardiac lipid peroxidation and decreased antioxidant biomarker levels. SO and (or) ALA supplementation ameliorated the deleterious effects of DZN intoxication. Treatment improved hematology and serum parameters, enhanced endogenous antioxidant status, and reduced lipid peroxidation. Importantly, they exerted synergistic hepatoprotective, nephroprotective, and cardioprotective effects. Our findings demonstrate that SO and (or) ALA supplementation can alleviate the toxic effects of DZN via their potent antioxidant and free radical-scavenging activities.

Phytochemicals prevent mitochondrial membrane permeabilization and protect SH-SY5Y cells against apoptosis induced by PK11195, a ligand for outer membrane translocator protein.

PubMed

Wu, Yuqiu; Shamoto-Nagai, Masayo; Maruyama, Wakako; Osawa, Toshihiko; Naoi, Makoto

2017-01-01

Epidemiological studies present the beneficial effects of dietary habits on prevention of aging-associated decline of brain function. Phytochemicals, the second metabolites of food, protect neuronal cells from cell death in cellular models of neurodegenerative disorders, and the neuroprotective activity has been ascribed to the anti-oxidant and anti-inflammatory functions. In this paper, the cellular mechanism of neuroprotection by phytochemicals was investigated, using the cellular model of mitochondrial apoptosis induced by PK11195, a ligand of outer membrane translocator protein, in SH-SY5Y cells. PK11195 induced mitochondrial membrane permeabilization with rapid transit production of superoxide (superoxide flashes) and calcium release from mitochondria, and activated apoptosis signal pathway. Study on the structure-activity relationship of astaxanthin, ferulic acid derivatives, and sesame lignans revealed that these phytochemicals inhibited mitochondrial membrane permeabilization and protected cells from apoptosis. Ferulic acid derivatives and sesame lignans inhibited or enhanced the mitochondrial pore formation and cell death by PK11195 according to their amphiphilic properties, not directly depending on the antioxidant activity. Regulation of pore formation at mitochondrial membrane is discussed as a novel mechanism behind neuroprotective activity of phytochemicals in aging and age-associated neurodegenerative disorders, and also behind dual functions of phytochemicals in neuronal and cancer cells.

MACH2: A Two-Dimensional Magnetohydrodynamic Simulation Code for Complex Experimental Configurations.

DTIC Science & Technology

1987-09-01

Eulerian or Lagrangian flow problems, use of real equations of state and transport properties from the Los Alamos National Laboratory SESAME package...permissible problem geometries; time differencing; and spatial discretization, centering, and differ- encing of MACH2. /. I." - Magnetohydrodynamics...R-A & Y7 24 9 5.2 THE IDEAL COORDINATE SYSTEM DTIC TAB 13 24 5.3 THE MATERIAL DERIVATIVE Uannounoed 0 26 Justifloatlo- 6. TIME DIFFERENCING 31 6.1

Lipid formation and γ-linolenic acid production by Mucor circinelloides and Rhizopus sp., grown on vegetable oil

PubMed Central

Tauk-Tornisielo, Sâmia M.; Arasato, Luciana S.; de Almeida, Alex F.; Govone, José S.; Malagutti, Eleni N.

2009-01-01

The fungi strains were tested in Bioscreen automated system to select the best nutritional source. Following, shaking submserse cultures were studied in media containing sole carbon or nitrogen source. The growth of these strains improved in media containing vegetable oil, with high concentration of lipids. The high concentration of γ-linolenic acid was obtained with M. circinelloides in culture containing sesame oil. PMID:24031370

An Integration of the Visual Media Via "Fat Albert and the Cosby Kids" into the Elementary School Curriculum as a Teaching Aid and Vehicle to Achieve Increased Learning.

ERIC Educational Resources Information Center

Cosby, William Henry, Jr.

This study examines the failure of urban schools to meet the educational needs of minority children and explores the possibilities of using television as a tool for educational change. It discusses three television series ("Sesame Street,""The Electric Company," and "Fat Albert and the Cosby Kids") with regard to their success as teaching/learning…

How lost "passenger" ants find their way home.

PubMed

Srinivasan, Mandyam V

2018-03-01

Animal navigation has fascinated biologists and engineers for centuries, and some of the most illuminating discoveries have come from the study of creatures with a brain no larger than a sesame seed. In an elegant recent study, Pfeiffer and Wittlinger (Science, 353, 1155-1157, 2016) have shown the means by which desert ants, carried from one nest to another by a relative, find their own way back home if they are accidentally dropped en route.

A new multimedia contaminant fate model for China: how important are environmental parameters in influencing chemical persistence and long-range transport potential?

PubMed

Zhu, Ying; Price, Oliver R; Tao, Shu; Jones, Kevin C; Sweetman, Andy J

2014-08-01

We present a new multimedia chemical fate model (SESAMe) which was developed to assess chemical fate and behaviour across China. We apply the model to quantify the influence of environmental parameters on chemical overall persistence (POV) and long-range transport potential (LRTP) in China, which has extreme diversity in environmental conditions. Sobol sensitivity analysis was used to identify the relative importance of input parameters. Physicochemical properties were identified as more influential than environmental parameters on model output. Interactive effects of environmental parameters on POV and LRTP occur mainly in combination with chemical properties. Hypothetical chemicals and emission data were used to model POV and LRTP for neutral and acidic chemicals with different KOW/DOW, vapour pressure and pKa under different precipitation, wind speed, temperature and soil organic carbon contents (fOC). Generally for POV, precipitation was more influential than the other environmental parameters, whilst temperature and wind speed did not contribute significantly to POV variation; for LRTP, wind speed was more influential than the other environmental parameters, whilst the effects of other environmental parameters relied on specific chemical properties. fOC had a slight effect on POV and LRTP, and higher fOC always increased POV and decreased LRTP. Example case studies were performed on real test chemicals using SESAMe to explore the spatial variability of model output and how environmental properties affect POV and LRTP. Dibenzofuran released to multiple media had higher POV in northwest of Xinjiang, part of Gansu, northeast of Inner Mongolia, Heilongjiang and Jilin. Benzo[a]pyrene released to the air had higher LRTP in south Xinjiang and west Inner Mongolia, whilst acenaphthene had higher LRTP in Tibet and west Inner Mongolia. TCS released into water had higher LRTP in Yellow River and Yangtze River catchments. The initial case studies demonstrated that SESAMe performed well on comparing POV and LRTP of chemicals in different regions across China in order to potentially identify the most sensitive regions. This model should not only be used to estimate POV and LRTP for screening and risk assessments of chemicals, but could potentially be used to help design chemical monitoring programmes across China in the future. Copyright © 2014 Elsevier Ltd. All rights reserved.

MSIAC Journal: Volume 2, Issue 10, September 2007

DTIC Science & Technology

2007-09-01

technology events ( y -axis) has been arranged by the year in which they occurred. Along the x-axis is year and age related information. The Year row is... Millennial cohorts. This is a transitory situation that will change in 20-years when few sponsors of the Pre-Sesame Street cohort will be work- ing...classroom education has focused primarily on the linguis- tic and logical-mathematical. Learners from the Gen-X and Millennial cohorts—Table 1—have

Prism users guide.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weirs, V. Gregory

2012-03-01

Prism is a ParaView plugin that simultaneously displays simulation data and material model data. This document describes its capabilities and how to use them. A demonstration of Prism is given in the first section. The second section contains more detailed notes on less obvious behavior. The third and fourth sections are specifically for Alegra and CTH users. They tell how to generate the simulation data and SESAME files and how to handle aspects of Prism use particular to each of these codes.

Effects of Tropical Rotation Crops on Meloidogyne arenaria Population Densities and Vegetable Yields in Microplots.

PubMed

McSorley, R; Dickson, D W; de Brito, J A; Hewlett, T E; Frederick, J J

1994-06-01

The effects of 12 summer crop rotation treatments on population densities of Meloidogyne arenaria race 1 and on yields of subsequent spring vegetable crops were determined in microplots. The crop sequence was: (i) rotation crops during summer 1991 ; (ii) cover crop of rye (Secale cereale) during winter 1991-92; (iii) squash (Cucurbita pepo) during spring 1992; (iv) rotation crops during summer 1992; (v) rye during winter 1992-93; (vi) eggplant (Solanum melongena) during spring 1993. The 12 rotation treatments were castor (Ricinus communis), cotton (Gossypium hirsutum), velvetbean (Mucuna deeringiana), crotalaria (Crotalaria spectabilis), fallow, hairy indigo (Indigofera hirsuta), American jointvetch (Aeschynomene americana), sorghum-sudangrass (Sorghum bicolor x S. sudanense), soybean (Glycine max), horsebean (Canavalia ensiformis), sesame (Sesamum indicum), and peanut (Arachis hypogaea). Compared to peanut, the first eight rotation treatments resulted in lower (P

Tropical rotation crops influence nematode densities and vegetable yields.

PubMed

McSorley, R; Dickson, D W; de Brito, J A; Hochmuth, R C

1994-09-01

The effects of eight summer rotation crops on nematode densities and yields of subsequent spring vegetable crops were determined in field studies conducted in north Florida from 1991 to 1993. The crop sequence was as follows: (i) rotation crops during summer 1991; (ii) cover crop of rye (Secale cereale) during winter 1991-92; (iii) 'Lemondrop L' squash (Cucurbita pepo) during spring 1992; (iv) rotation crops during summer 1992; (v) rye during winter 1992-93; (vi) 'Classic' eggplant (Solanum melongena) during spring 1993. The eight summer crop rotation treatments were as follows: 'Hale' castor (Ricinus communis), velvetbean (Mucuna deeringiana), sesame (Sesamum indicum), American jointvetch (Aeschynomene americana), weed fallow, 'SX- 17' sorghum-sudangrass (Sorghum bicolor x S. sudanense), 'Kirby' soybean (Glycine max), and 'Clemson Spineless' okra (Hibiscus esculentus) as a control. Rotations with castor, velvetbean, American jointvetch, and sorghum-sudangrass were most effective in maintaining the lowest population densities of Meloidogyne spp. (a mixture of M. incognita race 1 and M. arenaria race 1), but Paratrichodorus minor built up in the sorghum-sudangrass rotation. Yield of squash was lower (P

Manufacture of low-benzo(a)pyrene sesame seed (Sesamum indicum L.) oil using a self-designed apparatus.

PubMed

Yi, Ji Yoon; Kim, Hui Ju; Chung, Myong-Soo

2017-01-01

The aim of this study was to lower benzo(a)pyrene (BaP) contents in sesame seed oil (SSO) during manufacture by using a self-designed apparatus, to determine its optimal conditions, and to analyze antioxidants in SSO which might be related to BaP content reduction. Washing and spin-drying steps reduce exogenous BaP contamination, and the reduced moisture in seeds lowered BaP content in final SSO. A ventilation system in the roasting step inhibits BaP formation and reabsorption, followed by a controlled compression step. The optimal condition, a single washing cycle with 2-min spin-drying, 1350-rpm ventilation, and a single compression cycle, reduced the BaP content in SSO to 2.93 μg/kg, where the raw seeds had been spiked with 10-μg/kg BaP. Total phenolic contents showed a reversal pattern to the distribution of BaP contents. Sesamol and sesamolin were quantified by a high performance liquid chromatography-ultraviolet detector, and it was suggested that sesamol which is a strong antioxidant might have prevented BaP formation during the roasting step. This study enabled the commercial production of low-BaP SSO, and the data could be used in further investigations of the BaP content reduction mechanism with quantitative chemical analysis of the SSO composition.

Green-diode-pumped femtosecond Ti:Sapphire laser with up to 450 mW average power.

PubMed

Gürel, K; Wittwer, V J; Hoffmann, M; Saraceno, C J; Hakobyan, S; Resan, B; Rohrbacher, A; Weingarten, K; Schilt, S; Südmeyer, T

2015-11-16

We investigate power-scaling of green-diode-pumped Ti:Sapphire lasers in continuous-wave (CW) and mode-locked operation. In a first configuration with a total pump power of up to 2 W incident onto the crystal, we achieved a CW power of up to 440 mW and self-starting mode-locking with up to 200 mW average power in 68-fs pulses using semiconductor saturable absorber mirror (SESAM) as saturable absorber. In a second configuration with up to 3 W of pump power incident onto the crystal, we achieved up to 650 mW in CW operation and up to 450 mW in 58-fs pulses using Kerr-lens mode-locking (KLM). The shortest pulse duration was 39 fs, which was achieved at 350 mW average power using KLM. The mode-locked laser generates a pulse train at repetition rates around 400 MHz. No complex cooling system is required: neither the SESAM nor the Ti:Sapphire crystal is actively cooled, only air cooling is applied to the pump diodes using a small fan. Because of mass production for laser displays, we expect that prices for green laser diodes will become very favorable in the near future, opening the door for low-cost Ti:Sapphire lasers. This will be highly attractive for potential mass applications such as biomedical imaging and sensing.

Manufacture of low-benzo(a)pyrene sesame seed (Sesamum indicum L.) oil using a self-designed apparatus

PubMed Central

Yi, Ji Yoon; Kim, Hui Ju; Chung, Myong-Soo

2017-01-01

The aim of this study was to lower benzo(a)pyrene (BaP) contents in sesame seed oil (SSO) during manufacture by using a self-designed apparatus, to determine its optimal conditions, and to analyze antioxidants in SSO which might be related to BaP content reduction. Washing and spin-drying steps reduce exogenous BaP contamination, and the reduced moisture in seeds lowered BaP content in final SSO. A ventilation system in the roasting step inhibits BaP formation and reabsorption, followed by a controlled compression step. The optimal condition, a single washing cycle with 2-min spin-drying, 1350-rpm ventilation, and a single compression cycle, reduced the BaP content in SSO to 2.93 μg/kg, where the raw seeds had been spiked with 10-μg/kg BaP. Total phenolic contents showed a reversal pattern to the distribution of BaP contents. Sesamol and sesamolin were quantified by a high performance liquid chromatography-ultraviolet detector, and it was suggested that sesamol which is a strong antioxidant might have prevented BaP formation during the roasting step. This study enabled the commercial production of low-BaP SSO, and the data could be used in further investigations of the BaP content reduction mechanism with quantitative chemical analysis of the SSO composition. PMID:28278179

Hypolipidemic and hepatoprotective seeds mixture diet rich in omega-3 and omega-6 fatty acids.

PubMed

Makni, Mohamed; Fetoui, Hamadi; Garoui, El Mouldi; Gargouri, Nabil K; Jaber, Hazem; Makni, Jamel; Boudawara, Tahia; Zeghal, Najiba

2010-01-01

In vitro physicochemical and antioxidant properties of mixture of Flax/Sesame (LS) and Flax/Peanut (LA) and in vivo hypolipidemic, antioxidant and hepatoprotective activities were carried out to ascertain the claim of its utilisation against diseases. The seeds mixture rich in unsaturated fatty acids were prepared with 5/1 ratio of omega-6/omega-3 fatty acids and were orally administered ad libitum to rats by standard diet for 30 days. High cholesterol fed diet rats (CD-chol) exhibited a significant increase in total plasma and liver lipid parameters and atherogenicity and a significant decrease in high-density lipoproteins (HDL) and HDL/TC ratio (HTR). Administration of (LS) or (LA) seeds mixture to hypercholesterolemic rats (MS-LSchol and MS-LAchol groups respectively) significantly ameliorated lipid parameters and showed an increase of PUFAs (ALA and LA) and MUFAs and a decrease of SFAs in plasma and liver of MS-LSchol and MS-LAchol groups. Furthermore, malondialdehyde levels decreased and the efficiency of antioxidant defense system was improved compared to CD-chol group. Liver histological sections showed lipid storage in hepatocytes of CD-chol group and an improvement was noted in both supplemented groups. Our results suggested that seeds mixtures of Flax/Sesame and Flax/Peanut have anti-atherogenic and hepatoprotective effects. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

KSC-2011-5101

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronauts Mike Massimino and Doug Wheelock talk with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5090

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronauts Mike Massimino and Doug Wheelock talk with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

KSC-2011-5095

NASA Image and Video Library

2011-07-07

CAPE CANAVERAL, Fla. -- At Kennedy Space Center in Florida, NASA is hosting a Tweetup for 150 Twitter followers of space shuttle Atlantis' STS-135 mission to the International Space Station, selected from more than 5,500 online registrants. A Tweetup is an informal meeting of people who use the social messaging medium Twitter. Here, NASA astronauts Mike Massimino and Doug Wheelock talk with Sesame Street's Elmo. Sesame Street also is at Kennedy to film Elmo, as he learns about space exploration at NASA. Atlantis and its crew of four; Commander Chris Ferguson, Pilot Doug Hurley, Mission Specialists Sandy Magnus and Rex Walheim, are scheduled to lift off at 11:26 a.m. EDT on July 8 to deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts to the station. Atlantis also will fly the Robotic Refueling Mission experiment that will investigate the potential for robotically refueling existing satellites in orbit. In addition, Atlantis will return with a failed ammonia pump module to help NASA better understand the failure mechanism and improve pump designs for future systems. STS-135 will be the 33rd flight of Atlantis, the 37th shuttle mission to the space station, and the 135th and final mission of NASA's Space Shuttle Program. For more information visit, www.nasa.gov/mission_pages/shuttle/shuttlemissions/sts135/index.html. Photo credit: NASA/Troy Cryder

Standardized ileal digestibility of proteins and amino acids in sesame expeller and soya bean meal in weaning piglets.

PubMed

Aguilera, A; Reis de Souza, T C; Mariscal-Landín, G; Escobar, K; Montaño, S; Bernal, M G

2015-08-01

Apparent ileal digestibility (AID) of diets containing sesame expeller (SE) and soya bean meal (SBM) was determined using 15 piglets (Genetiporc(®)), weaned at 17 ± 0.4 days with average body weight of 6.4 ± 0.7 kg (Fertilis 20 × G Performance, Genetiporc(®), PIC México, Querétaro, México). Piglets were randomly assigned to three treatments: (i) a reference diet with casein as the sole protein source; (ii) a mixed diet of casein-SE; and (iii) a mixed diet of casein-SBM. The chemical composition of SE and SBM was determined, and AID and standardized ileal digestibility (SID) of crude protein (CP) and amino acids (AAs) were determined for each protein source. SE contained greater quantities of ether extract, neutral detergent fibre, phytic acid, methionine and arginine than SBM. Lysine and proline contents and trypsin inhibitor activity were higher in SBM than in SE. The AID and SID of CP and AA (except for lysine and proline) were similar in SE and SBM. The AID of lysine and proline was higher in SBM than in SE (p < 0.05), and the SID of proline was higher in SE than in SBM (p < 0.05). These findings indicate that SE is an appropriate alternative protein source for early weaned pigs. Journal of Animal Physiology and Animal Nutrition © 2014 Blackwell Verlag GmbH.

Comparison of the microbiological quality of environmentally friendly and conventionally grown vegetables sold at retail markets in Korea.

PubMed

Ryu, Jee-Hoon; Kim, Minju; Kim, Eun-Gyeong; Beuchat, Larry R; Kim, Hoikyung

2014-09-01

Fresh produce is usually eaten raw without cooking or heating, which may increase the probability of foodborne infection. The microbiological quality of 11 types of fresh, raw vegetables (romaine lettuce, sesame leaves, crown daisy, garlic chives, iceberg lettuce, cabbage, broccoli, leek, chili pepper, capsicum, and zucchini) purchased at retail markets in Iksan, Korea as affected by cultivation method (environmentally friendly vegetables [organic, pesticide-free, and low-pesticide vegetables] and conventionally grown vegetables) and harvest season was determined. Escherichia coli O157:H7 and Salmonella were not detected in all samples of vegetables tested. Aerobic mesophiles (>6 log cfu/g) were detected in environmentally friendly romaine lettuce and crown daisy and environmentally friendly and conventionally grown garlic chives, which also contained coliforms (>3 log cfu/g). Sesame leaf and crown daisy (regardless of cultivation method), as well as conventionally grown romaine lettuce and leek, contained >1 log cfu/g of E. coli. The overall microbiological quality of environmentally friendly and conventionally grown vegetables was not significantly different (P > 0.05). However, there were seasonal effects on populations of coliforms and generic E. coli on vegetables. The greatest numbers of microorganisms were isolated from environmentally friendly or conventionally grown vegetables purchased in winter. The vegetables, regardless of cultivation method or season, should be subjected to appropriate antimicrobial treatment to enhance their microbial safety. © 2014 Institute of Food Technologists®

Mousetrap: An integrated, open-source mouse-tracking package.

PubMed

Kieslich, Pascal J; Henninger, Felix

2017-10-01

Mouse-tracking - the analysis of mouse movements in computerized experiments - is becoming increasingly popular in the cognitive sciences. Mouse movements are taken as an indicator of commitment to or conflict between choice options during the decision process. Using mouse-tracking, researchers have gained insight into the temporal development of cognitive processes across a growing number of psychological domains. In the current article, we present software that offers easy and convenient means of recording and analyzing mouse movements in computerized laboratory experiments. In particular, we introduce and demonstrate the mousetrap plugin that adds mouse-tracking to OpenSesame, a popular general-purpose graphical experiment builder. By integrating with this existing experimental software, mousetrap allows for the creation of mouse-tracking studies through a graphical interface, without requiring programming skills. Thus, researchers can benefit from the core features of a validated software package and the many extensions available for it (e.g., the integration with auxiliary hardware such as eye-tracking, or the support of interactive experiments). In addition, the recorded data can be imported directly into the statistical programming language R using the mousetrap package, which greatly facilitates analysis. Mousetrap is cross-platform, open-source and available free of charge from https://github.com/pascalkieslich/mousetrap-os .

Analysis of Trans Fat in Edible Oils with Cooking Process

PubMed Central

Song, Juhee; Park, Joohyeok; Jung, Jinyeong; Lee, Chankyu; Gim, Seo Yeoung; Ka, HyeJung; Yi, BoRa; Kim, Mi-Ja; Kim, Cho-il

2015-01-01

Trans fat is a unsaturated fatty acid with trans configuration and separated double bonds. Analytical methods have been introduced to analyze trans fat content in foods including infrared (IR) spectroscopy, gas chromatography (GC), Fourier transform-infrared (FT-IR) spectroscopy, reverses-phase silver ion high performance liquid chromatography, and silver nitrate thin layer chromatography. Currently, FT-IR spectroscopy and GC are mostly used methods. Trans fat content in 6 vegetable oils were analyzed and processing effects including baking, stir-frying, pan-frying, and frying on the formation of trans fat in corn oil was evaluated by GC. Among tested vegetable oils, corn oil has 0.25 g trans fat/100 g, whereas other oils including rapeseed, soybean, olive, perilla, and sesame oils did not have detectable amount of trans fat content. Among cooking methods, stir-frying increased trans fat in corn oil whereas baking, pan-frying, and frying procedures did not make changes in trans fat content compared to untreated corn oils. However, the trans fat content was so low and food label can be declared as ‘0’ trans based on the regulation of Ministry of Food ad Drug Safety (MFDS) (< 2 g/100 g edible oil). PMID:26483890

Soliton trapping in fiber lasers.

PubMed

Zhao, L M; Tang, D Y; Zhang, H; Wu, X; Xiang, N

2008-06-23

We report on the soliton trapping in a fiber ring laser modelocked with a SESAM. It was observed that solitons along the two orthogonal polarization directions of the cavity with fairly large difference in central frequency and energy could be coupled together to form a group velocity locked vector soliton. In particular, due to that each of the coupled solitons forms its own soliton sidebands, two sets of soliton sidebands could be observed on the vector soliton spectrum. Numerical simulations have well confirmed the experimental observations.

Results from a limited area mesoscale numerical simulation for 10 April 1979

NASA Technical Reports Server (NTRS)

Kalb, M. W.

1985-01-01

Results are presented from a nine-hour limited area fine mesh (35-km) mesoscale model simulation initialized with SESAME-AVE I radiosonde data for Apr. 10, 1979 at 2100 GMT. Emphasis is on the diagnosis of mesoscale structure in the mass and precipitation fields. Along the Texas/Oklahoma border, independent of the short wave, convective precipitation formed several hours into the simulation and was organized into a narrow band suggestive of the observed April 10 squall line.

Vitamin E Succinate as an Adjuvant for Dendritic Cell Based Vaccines

DTIC Science & Technology

2006-07-01

which is soluble only in organic solvents like sesame oil, dimethylsulfoxide ( DMSO ) or ethanol (1-4), vesiculated α-TOS (Vα-TOS) is hydrophilic and is...mammary tumors, acts as an effective adjuvant. One of the major limitations of using α-TOS is its insolubility in aqueous solvents . Unlike α-TOS...with the long-term use of DMSO or ethanol that are commonly used to solubilize α-TOS for parenteral administration making Vα- TOS better suited for long

Ronald McDonald pregunta: "Puedes decir: 'dostortosdepurocarnederessalsaespeciallechugagueso- pepinillosycebollasenunpanconsemillasdeajonjoli'?" (Ronald McDonald Asks: "Can You Say: 'Two-All-Beef-Patties-Special-Sauce-Lettuce-Cheese-Pickles-Onions-On- A-Sesame-Seed-Bun'?" Activities in Spanish).

ERIC Educational Resources Information Center

Headrick, Robert J., Jr.

This booklet is intended for classroom use in first-year high school Spanish to acquaint students with the McDonald's fast food restaurants in Costa Rica. The specific objectives are for the student to: (1) discuss the similarities and differences between the American and Costa Rican McDonald's, (2) set up a miniature McDonald's in the classroom,…

Ronald McDonald dit: "Tout le monde connait: 'Deuxsteakshachessaucespecialesaladefromageoignons dansuntriplepainrondrecouvertdegrainsdesesames'" (Ronald McDonald Says: "Everyone Knows: 'Two-All-Beef-Patties-Special-Sauce-Lettuce-Cheese-Pickles- Onions-on-a-Sesame-Seed Bun'").

ERIC Educational Resources Information Center

Headrick, Robert J., Jr.

This booklet is intended for classroom use in first-year high school French to acquaint students with the McDonald's fast food restaurants in Paris. The specific objectives are for the student to: (1) discuss the similarities and differences between the American and Parisian McDonald's, (2) set up a miniature McDonald's in the classroom, (3) order…

Building Computer-Based Experiments in Psychology without Programming Skills.

PubMed

Ruisoto, Pablo; Bellido, Alberto; Ruiz, Javier; Juanes, Juan A

2016-06-01

Research in Psychology usually requires to build and run experiments. However, although this task has required scripting, recent computer tools based on graphical interfaces offer new opportunities in this field for researchers with non-programming skills. The purpose of this study is to illustrate and provide a comparative overview of two of the main free open source "point and click" software packages for building and running experiments in Psychology: PsychoPy and OpenSesame. Recommendations for their potential use are further discussed.

Co-extrusion of food grains-banana pulp for nutritious snacks: optimization of process variables.

PubMed

Mridula, D; Sethi, Swati; Tushir, Surya; Bhadwal, Sheetal; Gupta, R K; Nanda, S K

2017-08-01

Present study was undertaken to optimize the process conditions for development of food grains (maize, defatted soy flour, sesame seed)-banana based nutritious expanded snacks using extrusion processing. Experiments were designed using Box-Behnken design with banana pulp (8-24 g), screw speed (300-350 rpm) and feed moisture (14-16% w.b.). Seven responses viz. expansion ratio (ER), bulk density (BD), water absorption index (WAI), protein, minerals, iron and sensory acceptability were considered for optimizing independent parameters. ER, BD, WAI, protein content, total minerals, iron content, and overall acceptability ranged 2.69-3.36, 153.43-238.83 kg/m 3 , 4.56-4.88 g/g, 15.19-15.52%, 2.06-2.27%, 4.39-4.67 mg/100 g (w.b.) and 6.76-7.36, respectively. ER was significantly affected by all three process variables while BD was influenced by banana pulp and screw speed only. Studied process variables did not affected colour quality except 'a' value with banana pulp and screw speed. Banana pulp had positive correlation with water solubility index, total minerals and iron content and negative with WAI, protein and overall acceptability. Based upon multiple response analysis, optimized conditions were 8 g banana pulp, 350 rpm screw speed and 14% feed moisture indicating the protein, calorie, iron content and overall sensory acceptability in sample as 15.46%, 401 kcal/100 g, 4.48 mg/100 g and 7.6 respectively.

Brief overview of the long-lived radionuclide separation processes developed in france in connection with the spin program

NASA Astrophysics Data System (ADS)

Madic, Charles; Bourges, Jacques; Dozol, Jean-François

1995-09-01

To reduce the long-term potential hazards associated with the management of nuclear wastes generated by nuclear fuel reprocessing, one alternative is the transmutation of long-lived radionuclides into short-lived radionuclides by nuclear means (P & T strategy). In this context, according to the law passed by the French Parliament on 30 December 1991, the CEA launched the SPIN program for the design of long-lived radionuclide separation and nuclear incineration processes. The research in progress to define separation processes focused mainly on the minor actinides (neptunium, americium and curium) and some fission products, like cesium and technetium. To separate these long-lived radionuclides, two strategies were developed. The first involves research on new operating conditions for improving the PUREX fuel reprocessing technology. This approach concerns the elements neptunium and technetium (iodine and zirconium can also be considered). The second strategy involves the design of new processes; DIAMEX for the co-extraction of minor actinides from the high-level liquid waste leaving the PUREX process, An(III)/Ln(III) separation using tripyridyltriazine derivatives or picolinamide extracting agents; SESAME for the selective separation of americium after its oxidation to Am(IV) or Am(VI) in the presence of a heteropolytungstate ligand, and Cs extraction using a new class of extracting agents, calixarenes, which exhibit exceptional Cs separation properties, especially in the presence of sodium ion. This lecture focuses on the latest achievements in these research areas.

Selecting of a cytochrome P450cam SeSaM library with 3-chloroindole and endosulfan - Identification of mutants that dehalogenate 3-chloroindole.

PubMed

Kammoonah, Shaima; Prasad, Brinda; Balaraman, Priyadarshini; Mundhada, Hemanshu; Schwaneberg, Ulrich; Plettner, Erika

2018-01-01

Cytochrome P450 cam (a camphor hydroxylase) from the soil bacterium Pseudomonas putida shows potential importance in environmental applications such as the degradation of chlorinated organic pollutants. Seven P450 cam mutants generated from Sequence Saturation Mutagenesis (SeSaM) and isolated by selection on minimal media with either 3-chloroindole or the insecticide endosulfan were studied for their ability to oxidize of 3-chloroindole to isatin. The wild-type enzyme did not accept 3-chloroindole as a substrate. Mutant (E156G/V247F/V253G/F256S) had the highest maximal velocity in the conversion of 3-chloroindole to isatin, whereas mutants (T56A/N116H/D297N) and (G60S/Y75H) had highest k cat /K M values. Six of the mutants had more than one mutation, and within this set, mutation of residues 297 and 179 was observed twice. Docking simulations were performed on models of the mutant enzymes; the wild-type did not accommodate 3-chloroindole in the active site, whereas all the mutants did. We propose two potential reaction pathways for dechlorination of 3-chloroindole. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared Goldstone. Copyright © 2017 Elsevier B.V. All rights reserved.

Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine.

PubMed

Bradshaw, Heather B; Leishman, Emma

2016-05-01

Rates of osteoporosis are significantly lower in regions of the world where olive oil consumption is a dietary cornerstone. Olive oil may represent a source of oleoyl serine (OS), which showed efficacy in animal models of osteoporosis. Here, we tested the hypothesis that OS as well as structurally analogous N-acyl amide and 2-acyl glycerol lipids are present in the following cooking oils: olive, walnut, canola, high heat canola, peanut, safflower, sesame, toasted sesame, grape seed, and smart balance omega. Methanolic lipid extracts from each of the cooking oils were partially purified on C-18 solid-phase extraction columns. Extracts were analyzed with high-performance liquid chromatography-tandem mass spectrometry, and 33 lipids were measured in each sample, including OS and bioactive analogs. Of the oils screened here, walnut oil had the highest number of lipids detected (22/33). Olive oil had the second highest number of lipids detected (20/33), whereas grape-seed and high-heat canola oil were tied for lowest number of detected lipids (6/33). OS was detected in 8 of the 10 oils tested and the levels were highest in olive oil, suggesting that there is something about the olive plant that enriches this lipid. Cooking oils contain varying levels of bioactive lipids from the N-acyl amide and 2-acyl glycerol families. Olive oil is a dietary source of OS, which may contribute to lowered prevalence of osteoporosis in countries with high consumption of this oil.

Comparative effects of neonatal diethylstilbestrol on external genitalia development in adult males of two mouse strains with differential estrogen sensitivity

PubMed Central

Mahawong, Phitsanu; Sinclair, Adriane; Li, Yi; Schlomer, Bruce; Rodriguez, Esequiel; Ferretti, Max M.; Liu, Baomai; Baskin, Laurence S.; Cunha, Gerald R.

2014-01-01

The effect of neonatal exposure to diethylstilbestrol (DES), a potent synthetic estrogen, was examined to evaluate whether the CD-1 (estrogen insensitive, outbred) and C57 (estrogen sensitive, inbred) mouse strains differ in their response to estrogen disruption of male ExG differentiation. CD-1 and C57BL/6 litters were injected with sesame oil or DES (200 ng/g/5μl in sesame oil vehicle) every other day from birth to day 10. Animals were sacrificed at the following time points: birth, 5, 10 and 60 days postnatal. Neonatally DES-treated mice from both strains had many ExG abnormalities that included the following: (a) severe truncation of the prepuce and glans penis, (b) an abnormal urethral meatus, (c) ventral tethering of the penis, (d) reduced os penis length and glans width, (e) impaired differentiation of cartilage, (f) absence of urethral flaps, and (g) impaired differentiation of erectile bodies. Adverse effects of DES correlated with the expression of estrogen receptors within the affected tissues. While the effects of DES were similar in the more estrogen-sensitive C57BL/6 mice versus the less estrogen-sensitive CD-1 mice, the severity of DES effects was consistently greater in C57BL/6 mice. We suggest that many of the effects of DES, including the induction of hypospadias, are due to impaired growth and tissue fusion events during development. PMID:25449353

Anti-Colitic Effects of Kanjangs (Fermented Soy Sauce and Sesame Sauce) in Dextran Sulfate Sodium-Induced Colitis in Mice

PubMed Central

Song, Jia-Le; Choi, Jung-Ho; Seo, Jae-Hoon; Lim, Yaung-Iee

2014-01-01

Abstract This study was conducted to investigate the preventive effects of different kanjangs (Korean soy sauces), including acid-hydrolyzed soy sauce (AHSS), fermented soy sauce (FSS), and fermented sesame sauce (FSeS), on 2% dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6J mice. The fermented sauces, particularly FSeS, significantly suppressed DSS-induced body weight loss, increased colon length, and decreased colon weight/length ratios. Histological observations suggested that the fermented sauces prevented edema, mucosal damage, and the loss of crypts induced by DSS compared to the control mice and animals fed AHSS. FSeS and FSS decreased the serum levels of tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin (IL)-6, and IL-17α. mRNA expression of these cytokines as well as that of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in colon mucosa was also inhibited by the two sauces. Our results suggest that fermented sauces, especially FSeS, exert an anticolitic effect partially by reducing the serum levels of proinflammatory cytokines and inhibiting the mRNA expression of these factors in the colon tissue of mice treated with DSS. However, AHSS did not protect against DSS-induced colitis. In addition, low-dose treatment (4 mL/kg) with the fermented sauces resulted in greater anticolitic effects than consumption of a high quantity (8 mL/kg) of the sauces. PMID:25188463

Anti-colitic effects of kanjangs (fermented soy sauce and sesame sauce) in dextran sulfate sodium-induced colitis in mice.

PubMed

Song, Jia-Le; Choi, Jung-Ho; Seo, Jae-Hoon; Lim, Yaung-Iee; Park, Kun-Young

2014-09-01

This study was conducted to investigate the preventive effects of different kanjangs (Korean soy sauces), including acid-hydrolyzed soy sauce (AHSS), fermented soy sauce (FSS), and fermented sesame sauce (FSeS), on 2% dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6J mice. The fermented sauces, particularly FSeS, significantly suppressed DSS-induced body weight loss, increased colon length, and decreased colon weight/length ratios. Histological observations suggested that the fermented sauces prevented edema, mucosal damage, and the loss of crypts induced by DSS compared to the control mice and animals fed AHSS. FSeS and FSS decreased the serum levels of tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin (IL)-6, and IL-17α. mRNA expression of these cytokines as well as that of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in colon mucosa was also inhibited by the two sauces. Our results suggest that fermented sauces, especially FSeS, exert an anticolitic effect partially by reducing the serum levels of proinflammatory cytokines and inhibiting the mRNA expression of these factors in the colon tissue of mice treated with DSS. However, AHSS did not protect against DSS-induced colitis. In addition, low-dose treatment (4 mL/kg) with the fermented sauces resulted in greater anticolitic effects than consumption of a high quantity (8 mL/kg) of the sauces.

Ego-location and situational awareness in semistructured environments

NASA Astrophysics Data System (ADS)

Goodsell, Thomas G.; Snorrason, Magnus S.; Stevens, Mark R.; Stube, Brian; McBride, Jonah

2003-09-01

The success of any potential application for mobile robots depends largely on the specific environment where the application takes place. Practical applications are rarely found in highly structured environments, but unstructured environments (such as natural terrain) pose major challenges to any mobile robot. We believe that semi-structured environments-such as parking lots-provide a good opportunity for successful mobile robot applications. Parking lots tend to be flat and smooth, and cars can be uniquely identified by their license plates. Our scenario is a parking lot where only known vehicles are supposed to park. The robot looks for vehicles that do not belong in the parking lot. It checks both license plates and vehicle types, in case the plate is stolen from an approved vehicle. It operates autonomously, but reports back to a guard who verifies its performance. Our interest is in developing the robot's vision system, which we call Scene Estimation & Situational Awareness Mapping Engine (SESAME). In this paper, we present initial results from the development of two SESAME subsystems, the ego-location and license plate detection systems. While their ultimate goals are obviously quite different, our design demonstrates that by sharing intermediate results, both tasks can be significantly simplified. The inspiration for this design approach comes from the basic tenets of Situational Awareness (SA), where the benefits of holistic perception are clearly demonstrated over the more typical designs that attempt to solve each sensing/perception problem in isolation.

Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice.

PubMed

Truan, Jennifer S; Chen, Jian-Min; Thompson, Lilian U

2012-01-01

Flaxseed (FS) has a breast tumor-reducing effect, possibly because of its high content of secoisolariciresinol diglucoside (SDG) lignan. Sesame seed (SS) is rich in the lignan sesamin (SES) but is non-protective. Both lignans are metabolized to estrogen-like enterodiol and enterolactone. The objective of this study was to differentiate the effects of SDG and SES on established human estrogen receptor-positive breast tumors (MCF-7) in athymic mice with high serum estrogen to help explain the different effects of FS and SS. Mice were fed for 8 wk the basal diet (BD, control) or BD supplemented with 1 g/kg SDG or SES. SES reduced palpable tumor size by 23% compared to control, whereas SDG did not differ from SES or control. Both treatments reduced tumor cell proliferation, but only SES increased apoptosis. SDG and SES reduced human epidermal growth factor receptor 2 and endothelial growth factor receptor expressions, but only SES reduced downstream pMAPK. Neither treatment affected IGF-1R, vascular endothelial growth factor receptor-2, Akt, pAkt, or MAPK of the growth factor signaling pathway. Thus, at high serum estrogen levels, SDG may not account for the tumor reducing effect of FS. SES was more effective than SDG in reducing breast tumor growth, but its effect may have been lost when consumed as a component of SS.

Comparative studies on adsorptive removal of heavy metal ions by biosorbent, bio-char and activated carbon obtained from low cost agro-residue.

PubMed

Kırbıyık, Çisem; Pütün, Ayşe Eren; Pütün, Ersan

2016-01-01

In this study, Fe(III) and Cr(III) metal ion adsorption processes were carried out with three adsorbents in batch experiments and their adsorption performance was compared. These adsorbents were sesame stalk without pretreatment, bio-char derived from thermal decomposition of biomass, and activated carbon which was obtained from chemical activation of biomass. Scanning electron microscopy and Fourier transform-infrared techniques were used for characterization of adsorbents. The optimum conditions for the adsorption process were obtained by observing the influences of solution pH, adsorbent dosage, initial solution concentration, contact time and temperature. The optimum adsorption efficiencies were determined at pH 2.8 and pH 4.0 for Fe(III) and Cr(III) metal ion solutions, respectively. The experimental data were modelled by different isotherm models and the equilibriums were well described by the Langmuir adsorption isotherm model. The pseudo-first-order, pseudo-second-order kinetic, intra-particle diffusion and Elovich models were applied to analyze the kinetic data and to evaluate rate constants. The pseudo-second-order kinetic model gave a better fit than the others. The thermodynamic parameters, such as Gibbs free energy change ΔG°, standard enthalpy change ΔH° and standard entropy change ΔS° were evaluated. The thermodynamic study showed the adsorption was a spontaneous endothermic process.

Intelligent Agent Technology

NASA Technical Reports Server (NTRS)

1996-01-01

Open Sesame! is the first commercial software product that learns user's behavior, and offers automation and coaching suggestions to the user. The neural learning module looks for repetitive patterns that have not been automated; when it finds one, it creates an observation and, upon approval, automates the task. The manufacturer, Charles River Analytics, credits Langley Research Center and Johnson Space Center Small Business Innovation Research grants and the time the president and vice president spent at the two centers in the 1970s as being essential to the development of their product line.

Germanium multiphase equation of state

DOE PAGES

Crockett, Scott D.; Lorenzi-Venneri, Giulia De; Kress, Joel D.; ...

2014-05-07

A new SESAME multiphase germanium equation of state (EOS) has been developed using the best available experimental data and density functional theory (DFT) calculations. The equilibrium EOS includes the Ge I (diamond), the Ge II (β-Sn) and the liquid phases. The foundation of the EOS is based on density functional theory calculations which are used to determine the cold curve and the Debye temperature. Results are compared to Hugoniot data through the solid-solid and solid-liquid transitions. We propose some experiments to better understand the dynamics of this element

Aflatoxin contamination in foods and foodstuffs in Tokyo: 1986-1990.

PubMed

Tabata, S; Kamimura, H; Ibe, A; Hashimoto, H; Iida, M; Tamura, Y; Nishima, T

1993-01-01

Aflatoxins were determined in 3054 samples of foods or foodstuffs, including cereals, nuts, beans, spices, dairy products, dry fruits, and edible oil. Samples were collected in Tokyo from 1986 to 1990. Aflatoxins were found in rice products, adlay, corn, crude sugar, peanut products, pistachio nuts, brazil nuts, sesame products, butter beans, white pepper, red pepper, paprika, nutmeg, and mixed spices. The highest incidence of aflatoxin contamination was observed in nutmeg (80%), and the highest level of aflatoxin B1 was observed in pistachio nuts (1382 ppb).

[Antioxidant activity of vegetable oils with various omega-6/omega-3 fatty acids ratio].

PubMed

Guseva, D A; Prozorovskaia, N N; Shironin, A V; Sanzhakov, M A; Evteeva, N M; Rusina, I F; Kasaikina, O T

2010-01-01

Antioxidant activity and the oxidative stability were investigated in flax, sesame, silybum oils and oils with different omega-6/omega-3 fatty acid ratio. The content of antioxidants (AO) in crude oils and their reactivity towards peroxyl radicals were studied using kinetic method for addition of oil in a model reaction of cumol oxidation. There were correlations between PUFA/omega-9 and thermal stability (50 degrees C); between gamma-tocopherol content and resistantance to oxidative changes after storage at (10 +/- 2) degrees C for 6 months.

Transverse ageostrophic circulations associated with elevated mixed layers

NASA Technical Reports Server (NTRS)

Keyser, D.; Carlson, T. N.

1984-01-01

The nature of the frontogenetically forced transverse ageostrophic circulations connected with elevated mixed layer structure is investigated as a first step toward diagnosing the complex vertical circulation patterns occurring in the vicinity of elevated mixed layers within a severe storm environment. The Sawyer-Eliassen ageostrophic circulation equation is reviewed and applied to the elevated mixed layer detected in the SESAME IV data set at 2100 GMT of May 9, 1979. The results of the ageostrophic circulation diagnosis are confirmed and refined by considering an analytic specification for the elevated mixed layer structure.

Mid-infrared passively switched pulsed dual wavelength Ho3+-doped fluoride fiber laser at 3 μm and 2 μm

PubMed Central

Li, Jianfeng; Luo, Hongyu; Wang, Lele; Liu, Yong; Yan, Zhijun; Zhou, Kaiming; Zhang, Lin; Turistsyn, Sergei K.

2015-01-01

Cascade transitions of rare earth ions involved in infrared host fiber provide the potential to generate dual or multiple wavelength lasing at mid-infrared region. In addition, the fast development of saturable absorber (SA) towards the long wavelengths motivates the realization of passively switched mid-infrared pulsed lasers. In this work, by combing the above two techniques, a new phenomenon of passively Q-switched ~3 μm and gain-switched ~2 μm pulses in a shared cavity was demonstrated with a Ho3+-doped fluoride fiber and a specifically designed semiconductor saturable absorber (SESAM) as the SA. The repetition rate of ~2 μm pulses can be tuned between half and same as that of ~3 μm pulses by changing the pump power. The proposed method here will add new capabilities and more flexibility for generating mid-infrared multiple wavelength pulses simultaneously that has important potential applications for laser surgery, material processing, laser radar, and free-space communications, and other areas. PMID:26041105

Evidence against protective role of sex hormone estrogen in Cisplatin-induced nephrotoxicity in ovarectomized rat model.

PubMed

Pezeshki, Zahra; Nematbakhsh, Mehdi; Nasri, Hamid; Talebi, Ardeshir; Pilehvarian, Ali-Asghar; Safari, Tahereh; Eshraghi-Jazi, Fatemeh; Haghighi, Maryam; Ashrafi, Farzaneh

2013-01-01

Cisplatin (CP) is an effective drug in cancer therapy to treat the solid tumors, but it is accompanied with nephrotoxicity. The protective effect of estrogen in cardiovascular diseases is well-documented; but its nephron-protective effect against CP-induced nephrotoxicity is not completely understood. Thirty ovarectomized Wistar rats were divided in to five groups. Groups 1-3 received different doses of estradiol valerate (0.5, 2.5 and 10 mg/kg/week) in sesame oil for 4 weeks, and at the end of week 3, a single dose of CP (7 mg/kg, intraperitoneal [IP]) was administrated. Group 4 (positive control) received the same regimen as group 1-3 without estradiol without vehicle. The negative control group (Group 5) received sesame oil during the study. The animals were sacrificed 1 week after CP injection for histopathological studies. The serum level of blood urea nitrogen and creatinine, kidney tissue damage score (KTDS), kidney weight and percentage of body weight change in CP-treated groups significantly increased (P < 0.05), however, there were no significant differences detected between the estrogen-treated groups (Groups 1-3) and the positive control group (Group 4). Although, estradiol administration enhanced the serum level of nitrite, it was not affected by CP. Finally, significant correlation between KTDS and kidney weight was detected (r (2) = 0.63, P < 0.01). Estrogen is not nephron-protective against CP-induced nephrotoxicity. Moreover, it seems that the mechanism may be related to estrogen-induced oxidative stress in the kidney, which may promote the nephrotoxicity.

In vitro and in vivo evaluation of the metabolism and pharmacokinetics of sebacoyl dinalbuphine.

PubMed

Pao, Li-Heng; Hsiong, Cheng-Huei; Hu, Oliver Yoa-Pu; Wang, Jhi-Jung; Ho, Shung-Tai

2005-03-01

A diester prodrug of nalbuphine, sebacoyl dinalbuphine (SDN), and its long-acting formulation are currently being developed to prolong the duration of nalbuphine. A comparative in vitro hydrolysis study was conducted for SDN in rat, rabbit, dog, and human blood. Both SDN and nalbuphine in blood or plasma were measured by high-performance liquid chromatography. The hydrolysis rates of SDN in blood were ranked as follows: rat > rabbit > human > dog. The rapid formation of nalbuphine in the blood accounted for almost 100% of the prodrug, which supported the contention that nalbuphine is the major metabolite after SDN hydrolysis. The hydrolysis profiles of SDN were similar both in plasma and in red blood cells when compared in the blood. In vitro release results of SDN long-acting formulation showed that the rate-limited step of SDN hydrolysis to nalbuphine in blood is the penetration of SDN from oil into the blood. After intravenous administration of SDN in sesame oil into rats, nalbuphine quickly appeared in plasma and, thereafter, exhibited monoexponential decay. Pharmaceutical dosage forms affecting the drug disposition kinetics were demonstrated after intravenous administration. The AUC of nalbuphine was significantly higher and clearance was significantly lower, without changes in the t(1/2) of nalbuphine after intravenous dosing of SDN in sesame oil when compared with that of intravenous dosing with nalbuphine HCl in rats. Overall, these results suggest that SDN fulfilled the original pro-soft drug design in which the prodrug can rapidly metabolize to nalbuphine, and no other unexpected compounds were apparent in the blood.

Preparation, characterization and in vitro evaluation of microemulsion of raloxifene hydrochloride.

PubMed

Golmohammadzadeh, Shiva; Farhadian, Nafiseh; Biriaee, Amir; Dehghani, Faranak; Khameneh, Bahman

2017-10-01

Raloxifene hydrochloride (RLX) is a selective estrogen receptor modulator which is orally used for treatment of osteoporosis and prevention of breast cancer. The drug has low aqueous solubility and bioavailability. The aim of the present study is to formulate and characterize oil-in-water microemulsion systems for oral delivery of RLX. To enhance the drug aqueous solubility, microemulsion based on sesame oil was prepared. Sesame oil and Tween 80 were selected as the drug solvent oil and surfactant, respectively. In the first and second formulations, Edible glycerin and Span 80 were applied as co-surfactant, respectively. Pseudo-ternary phase diagrams showed that the best surfactant/co-surfactant ratios in the first and second formulations were 4:1 and 9:1, respectively. The particle size of all free drug-loaded and drug loaded samples were in the range of 31.25 ± 0.3 nm and 60.9 ± 0.1 nm, respectively. Electrical conductivity coefficient and refractive index of all microemulsion samples confirmed the formation of oil-in-water type of microemulsion. In vitro drug release profile showed that after 24 hours, 46% and 63% of the drug released through the first formulation in 0.1% (w/v) Tween 80 in distilled water as a release medium and phosphate buffer solution (PBS) at pH = 5.5, respectively. These values were changed to 57% and 98% for the second formulation. Results confirmed that the proposed microemulsion system containing RLX could improve and control the drug release profile in comparison to conventional dosage form.

Debriefing olympics-a workshop concept to stimulate the adaptation of debriefings to learning contexts.

PubMed

Dieckmann, Peter

2012-06-01

Debriefing is important in simulation-based education but rarely studied empirically. In this article, I describe an experience-based workshop concept that was tested with approximately 80 participants during the Annual Meeting of the Society in Europe for Simulation Applied to Medicine (SESAM), June 2 to 4, 2011, in Granada, Spain. On a metalevel, the goal of the workshop was to raise the awareness of debriefing as an important part of simulation-based learning and to increase the awareness about different styles of debriefing-possibly stimulating further investigations of debriefings.

Nonlinear mirror modelocking of a bounce geometry laser.

PubMed

Thomas, G M; Bäuerle, A; Farrell, D J; Damzen, M J

2010-06-07

We present the investigation of nonlinear mirror modelocking (NLM) of a bounce amplifier laser. This technique, a potential rival to SESAM modelocking, uses a nonlinear crystal and a dichroic mirror to passively modelock a Nd:GdVO(4) slab bounce amplifier operating at 1063nm. At 11.3W, we present the highest power achieved using the NLM technique, using type-II phase-matched KTP, with a pulse duration of 57ps. Using type-I phase-matched BiBO, modelocking was achieved with a shorter pulse duration of 5.7ps at an average power of 7.1W.

Broadly tunable femtosecond mode-locking in a Tm:KYW laser near 2 μm.

PubMed

Lagatsky, A A; Calvez, S; Gupta, J A; Kisel, V E; Kuleshov, N V; Brown, C T A; Dawson, M D; Sibbett, W

2011-05-09

Efficient mode-locking in a Tm:KY(WO(4))(2) laser is demonstrated by using InGaAsSb quantum-well SESAMs. Self-starting ultrashort pulse generation was realized in the 1979-2074 nm spectral region. Maximum average output power up to 411 mW was produced around 1986 nm with the corresponding pulse duration and repetition rate of 549 fs and 105 MHz respectively. Optimised pulse durations of 386 fs were produced with an average power of 235 mW at 2029 nm. © 2011 Optical Society of America

Frequency-doubled passively Q-switched microchip laser producing 225  ps pulses at 671  nm.

PubMed

Nikkinen, Jari; Korpijärvi, Ville-Markus; Leino, Iiro; Härkönen, Antti; Guina, Mircea

2016-11-15

We report a 671 nm laser source emitting 225 ps pulses with an average power of 55 mW and a repetition rate of 444 kHz. The system consists of a 1342 nm SESAM Q-switched Nd:YVO₄ microchip master oscillator and a dual-stage Nd:YVO₄ power amplifier. The 1342 nm signal was frequency-doubled to 671 nm using a periodically poled lithium niobate crystal. This laser source provides a practical alternative for applications requiring high energy picosecond pulses, such as time-gated Raman spectroscopy.

AM363 martensitic stainless steel: A multiphase equation of state

NASA Astrophysics Data System (ADS)

De Lorenzi-Venneri, Giulia; Crockett, Scott D.

2017-01-01

A multiphase equation of state for stainless steel AM363 has been developed within the Opensesame approach and has been entered as material 4295 in the LANL-SESAME Library. Three phases were constructed separately: the low pressure martensitic phase, the austenitic phase and the liquid. Room temperature data and the explicit introduction of a magnetic contribution to the free energy determined the martensitic phase, while shock Hugoniot data was used to determine the austenitic phase and the phase boundaries. More experimental data or First Principles calculations would be useful to better characterize the liquid.

A Survey of Self-Reported Food Allergy and Food-Related Anaphylaxis among Young Adult Students at Kuwait University, Kuwait.

PubMed

Ali, Fatima

2017-01-01

To conduct a survey on self-reported food allergy to milk, egg, peanuts, tree nuts, fish, shellfish, wheat, and sesame, as well as reported food-related anaphylaxis and epinephrine prescription practices among Kuwaiti students attending Kuwait University. One thousand questionnaires that included data on age, gender, presence of food allergies, and associated details were distributed. All participants reporting an allergy were categorized as having a perceived food allergy. Those with a convincing clinical history and history of undergoing diagnostic food allergy testing were further categorized as having a probable food allergy. Of the 1,000 questionnaires, 865 (86.5%) were completed. Of the 865 students, 104 (12.02%) reported food allergy (perceived), and 47 of these (45.19%) were probable food allergies. For milk (46.7%), peanut (35.7%), fish (60%), and sesame (50%), probable food allergy occurred in early childhood (≤5 years) while those of egg (44.4%) and wheat (57.1%) occurred in late childhood (6-10 years), and shellfish (40%) occurred in early adolescence (11-15 years). Of the 47 students with a probable food allergy, 28 (59.6%) were moderate to severe: 20 (71%) of these moderate-to-severe allergy cases reported at least 1 food-related anaphylactic episode while 8 (29%) denied such episodes. Equally important, of the 28 students, 6 (21%) received an autoinjectable epinephrine prescription, while 22 (79%) did not receive any. In this study the reported occurrence of perceived food allergy was low and probable food allergy occurred mostly in early childhood. Milk, egg, and nut allergies were the most commonly reported in both groups. © 2017 S. Karger AG, Basel.

Impact of applying edible oils to silk channels on ear pests of sweet corn.

PubMed

Ni, Xinzhi; Sparks, Alton N; Riley, David G; Li, Xianchun

2011-06-01

The impact of applying edible oils to corn silks on ear-feeding insects in sweet corn, Zea mays L., production was evaluated in 2006 and 2007. Six edible oils used in this experiment were canola, corn, olive, peanut, sesame, and soybean. Water and two commercial insecticidal oils (Neemix neem oil and nC21 Sunspray Ultrafine, a horticultural mineral oil) were used as the controls for the experiment. Six parameters evaluated in this experiment were corn earworm [Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae)] damage rating, the number of sap beetle [Carpophilus spp. (Coleoptera: Nitidulidae)] adults and larvae, the number of corn silk fly (or picture-winged fly) (Diptera: Ulidiidae) larvae, common smut [Ustilago maydis (D.C.) Corda] infection rate, and corn husk coverage. Among the two control treatments, neem oil reduced corn earworm damage at both pre- and postpollination applications in 2006, but not in 2007, whereas the mineral oil applied at postpollination treatments reduced corn earworm damage in both years. The mineral oil also reduced the number of sap beetle adults, whereas the neem oil applied at postpollination attracted the most sap beetle adults in 2007. Among the six edible oil treatments, the corn and sesame oils applied at postpollination reduced corn earworm damage only in 2007. The application of the peanut oil at postpollination attracted more sap beetle adults in 2006, and more sap beetle larvae in 2007. Olive and neem oils significantly reduced husk coverage compared with the water control in both years. The mineral oil application consistently increased smut infection rate in both 2006 and 2007. Ramifications of using oil treatments in ear pest management also are discussed.

Effects of Ayurvedic Oil-Dripping Treatment with Sesame Oil vs. with Warm Water on Sleep: A Randomized Single-Blinded Crossover Pilot Study.

PubMed

Tokinobu, Akiko; Yorifuji, Takashi; Tsuda, Toshihide; Doi, Hiroyuki

2016-01-01

Ayurvedic oil-dripping treatment (Shirodhara) is often used for treating sleep problems. However, few properly designed studies have been conducted, and the quantitative effect of Shirodhara is unclear. This study sought to quantitatively evaluate the effect of sesame oil Shirodhara (SOS) against warm water Shirodhara (WWS) on improving sleep quality and quality of life (QOL) among persons reporting sleep problems. This randomized, single-blinded, crossover study recruited 20 participants. Each participant received seven 30-minute sessions within 2 weeks with either liquid. The washout period was at least 2 months. The Shirodhara procedure was conducted by a robotic oil-drip system. The outcomes were assessed by the Pittsburgh Sleep Quality Index (PSQI) for sleep quality, Epworth Sleepiness Scale (ESS) for daytime sleepiness, World Health Organization Quality of Life 26 (WHO-QOL26) for QOL, and a sleep monitor instrument for objective sleep measures. Changes between baseline and follow-up periods were compared between the two types of Shirodhara. Analysis was performed with generalized estimating equations. Of 20 participants, 15 completed the study. SOS improved sleep quality, as measured by PSQI. The SOS score was 1.83 points lower (95% confidence interval [CI], -3.37 to -0.30) at 2-week follow-up and 1.73 points lower (95% CI, -3.84 to 0.38) than WWS at 6-week follow-up. Although marginally significant, SOS also improved QOL by 0.22 points at 2-week follow-up and 0.19 points at 6-week follow-up compared with WWS. After SOS, no beneficial effects were observed on daytime sleepiness or objective sleep measures. This pilot study demonstrated that SOS may be a safe potential treatment to improve sleep quality and QOL in persons with sleep problems.

Demographic predictors of peanut, tree nut, fish, shellfish, and sesame allergy in Canada.

PubMed

Ben-Shoshan, M; Harrington, D W; Soller, L; Fragapane, J; Joseph, L; Pierre, Y St; Godefroy, S B; Elliott, S J; Clarke, A E

2012-01-01

Background. Studies suggest that the rising prevalence of food allergy during recent decades may have stabilized. Although genetics undoubtedly contribute to the emergence of food allergy, it is likely that other factors play a crucial role in mediating such short-term changes. Objective. To identify potential demographic predictors of food allergies. Methods. We performed a cross-Canada, random telephone survey. Criteria for food allergy were self-report of convincing symptoms and/or physician diagnosis of allergy. Multivariate logistic regressions were used to assess potential determinants. Results. Of 10,596 households surveyed in 2008/2009, 3666 responded, representing 9667 individuals. Peanut, tree nut, and sesame allergy were more common in children (odds ratio (OR) 2.24 (95% CI, 1.40, 3.59), 1.73 (95% CI, 1.11, 2.68), and 5.63 (95% CI, 1.39, 22.87), resp.) while fish and shellfish allergy were less common in children (OR 0.17 (95% CI, 0.04, 0.72) and 0.29 (95% CI, 0.14, 0.61)). Tree nut and shellfish allergy were less common in males (OR 0.55 (95% CI, 0.36, 0.83) and 0.63 (95% CI, 0.43, 0.91)). Shellfish allergy was more common in urban settings (OR 1.55 (95% CI, 1.04, 2.31)). There was a trend for most food allergies to be more prevalent in the more educated (tree nut OR 1.90 (95% CI, 1.18, 3.04)) and less prevalent in immigrants (shellfish OR 0.49 (95% CI, 0.26, 0.95)), but wide CIs preclude definitive conclusions for most foods. Conclusions. Our results reveal that in addition to age and sex, place of residence, socioeconomic status, and birth place may influence the development of food allergy.

Nanostructured Lipid Carriers (NLC) as Vehicles for Topical Administration of Sesamol: In Vitro Percutaneous Absorption Study and Evaluation of Antioxidant Activity.

PubMed

Puglia, Carmelo; Lauro, Maria Rosaria; Offerta, Alessia; Crascì, Lucia; Micicchè, Lucia; Panico, Anna Maria; Bonina, Francesco; Puglisi, Giovanni

2017-03-01

Sesamol is a natural phenolic compound extracted from Sesamum indicum seed oil. Sesamol is endowed with several beneficial effects, but its use as a topical agent is strongly compromised by unfavorable chemical-physical properties. Therefore, to improve its characteristics, the aim of the present work was the formulation of nanostructured lipid carriers as drug delivery systems for topical administration of sesamol.Two different nanostructured lipid carrier systems have been produced based on the same solid lipid (Compritol® 888 ATO) but in a mixture with two different kinds of oil phase such as Miglyol® 812 (nanostructured lipid carrier-M) and sesame oil (nanostructured lipid carrier-PLUS). Morphology and dimensional distribution of nanostructured lipid carriers have been characterized by differential scanning calorimetry and photon correlation spectroscopy, respectively. The release pattern of sesamol from nanostructured lipid carriers was evaluated in vitro determining drug percutaneous absorption through excised human skin. Furthermore, an oxygen radical absorbance capacity assay was used to determine their antioxidant activity.From the results obtained, the method used to formulate nanostructured lipid carriers led to a homogeneous dispersion of particles in a nanometric range. Sesamol has been encapsulated efficiently in both nanostructured lipid carriers, with higher encapsulation efficiency values (> 90 %) when sesame oil was used as the oil phase (nanostructured lipid carrier-PLUS). In vitro evidences show that nanostructured lipid carrier dispersions were able to control the rate of sesamol diffusion through the skin, with respect to the reference formulations.Furthermore, the oxygen radical absorbance capacity assay pointed out an interesting and prolonged antioxidant activity of sesamol, especially when vehiculated by nanostructured lipid carrier-PLUS. Georg Thieme Verlag KG Stuttgart · New York.

Androgen Supplementation During Aging: Development of a Physiologically Appropriate Protocol

PubMed Central

Sorwell, Krystina G.; Garyfallou, Vasilios T.; Garten, Jamie; Weiss, Alison; Renner, Laurie; Neuringer, Martha; Kohama, Steven G.

2014-01-01

Abstract Men show an age-related decline in the circulating levels of testosterone (T) and dehydroepiandrosterone sulfate (DHEAS). Consequently, there is interest in developing androgen supplementation paradigms for old men that replicate the hormone profiles of young adults. In the present study, we used old (21–26 years old) male rhesus monkeys as a model to examine the efficacy of an androgen supplementation paradigm that comprised oral T administration (12 mg/kg body weight, dissolved in sesame oil/chocolate) in the evening, and two oral DHEA administrations, 3 hr apart (0.04 mg/kg body weight, dissolved in sesame oil/chocolate) in the morning. After 5 days of repeated hormone supplementation, serial blood samples were remotely collected from each animal hourly across the 24-hr day, and assayed for cortisol, DHEAS, T, 5α-dihydrotestosterone (DHT), estrone (E1), and 17β-estradiol (E2). Following androgen supplementation, T levels were significantly elevated and this was associated with a more sustained nocturnal elevation of T's primary bioactive metabolites, DHT and E1 and E2. Plasma DHEAS levels were also significantly elevated after androgen supplementation; DHEAS levels rose in the early morning and gradually declined during the course of the day, closely mimicking the profiles observed in young adults (7–12 years old); in contrast, cortisol levels were unaltered by the supplementation. Together the data demonstrate a non-invasive androgen supplementation paradigm that restores youthful circulating androgen levels in old male primates. Because this paradigm preserves the natural circulating circadian hormone patterns, we predict that it will produce fewer adverse side effects, such as perturbed sleep or cognitive impairment. PMID:24134213

Effectiveness of a multimedia outreach kit for families of wounded veterans.

PubMed

Walker, David Ian; Cardin, Jean-François; Chawla, Neelu; Topp, David; Burton, Thomaseo; Macdermid Wadsworth, Shelley

2014-04-01

Young children in military families with a member who has a life changing injury can experience emotional difficulties and behavior changes. This study evaluated a Sesame Workshop multimedia kit called: Talk, Listen, Connect: Changes (TLC-II(C); 2008). The kit, which included video and print materials, aimed to help caregivers (i.e., at-home partner, at-home relative or family member of a current or discharged military member) assist young children as they adjusted to their parent's injury. We expected that the materials would be used and their quality evaluated. We hypothesized that use of the materials would produce improvements in caregiver and child outcomes as well as reductions in perceptions of disruption in the home. We also predicted that kit-use would have a positive impact on the family. One-hundred and fifty three families with children aged 2-8 years were randomly assigned to receive the kit being evaluated (TLC-II(C)) or a control kit (Healthy Habits for Life (HHL)), also developed by Sesame Workshop. Group outcomes were compared four weeks following receipt of the kits using multivariate analysis of variance. All materials were well used and highly rated. All caregivers reported less social isolation, less child aggression, and significantly less disruptive home environments after kit use. Test group caregivers reported significantly greater reductions in depressive symptoms and significant increases in children's social competence over time in comparison to the control group. These results signal important improvements among families as a consequence of using either test or control materials. As a preventative intervention designed for families with an injured member, TLC-II(C) was particularly effective at improving coping. Copyright © 2014 Elsevier Inc. All rights reserved.

An Antiprogestin, CDB4124, Blocks Progesterone’s Attenuation of the Negative Effects of a Mild Stress on Sexual Behavior

PubMed Central

Uphouse, Lynda; Hiegel, Cindy

2012-01-01

These experiments were designed to test the hypothesis that a progesterone receptor antagonist would block progesterone’s ability to reduce the negative effects of a 5 min restraint on female rat sexual behavior. Ovariectomized Fisher rats were injected with 10 μg estradiol benzoate. Two days later, rats were injected subcutaneously (sc) with the progesterone receptor antagonist, CDB4124 (17 α-acetoxy-21-methoxy-11β-[4-N,N-dimethyaminopheny]-19-norpregna-4,9-dione-3,20-dione) (60 mg/kg), or vehicle (20% DMSO + propylene glycol). One hr later, rats were injected sc with 500 μg progesterone or vehicle (sesame seed oil). Rats were assigned to one of three different treatment conditions: (1) (ECV) estradiol benzoate, CDB4124, sesame seed oil vehicle, (2) (ECP) estradiol benzoate, CDB4124, progesterone, and (3) (EVP) estradiol benzoate, DMSO/propylene glycol vehicle, progesterone. That afternoon sexual behavior was examined before and after a 5 min restraint experience. Before restraint, lordosis behavior was comparable across treatment conditions but only progesterone-treated rats exhibited proceptive behavior. CDB4124 did not block progesterone’s induction of proceptivity. However, after restraint, CDB4124 attenuated the positive effects of progesterone on all sexual behaviors examined. The restraint experience inhibited sexual behavior in rats treated with estradiol benzoate and CDB4124 and in rats treated with estradiol benzoate, CDB4124, and progesterone but not in rats given estradiol benzoate and progesterone without CDB4124. These findings are consistent with the hypothesis that progesterone receptors mediate progesterone’s ability to reduce the negative sexual behavioral effects of a mild stressor. PMID:23153933

Effect of oil gum massage therapy on common pathogenic oral microorganisms - A randomized controlled trial

PubMed Central

Singla, Nishu; Acharya, Shashidhar; Martena, Suganthi; Singla, Ritesh

2014-01-01

Objectives: (i) To assess reduction in Streptococcus mutans and Lactobacillus species count in saliva sample after ten minutes of oil gum massage therapy (massage of gingival tissues) per day for three weeks with sesame oil, olive oil, and coconut oil in three different groups of subjects. (ii) To compare the efficacy between three different oils and the “gold standard” chlorhexidine gel. (iii) To assess reduction in gingival scores and plaque scores of study subjects. Materials and Methods: Study design – Single center, parallel design, and triple blind randomized clinical study with four treatment groups. Participants: 32 of the 40 study subjects working as housekeeping personnel at Kasturba Hospital, Manipal; aged 18-55 years completed the three-week study period. Interventions: Subjects were randomly assigned to massage their gingiva everyday for three weeks with sesame oil, olive oil, coconut oil (tests), and Chlorhexidine gel (control). Oral health status and paraffin stimulated saliva samples were obtained at baseline and after three weeks of oil gum massage therapy. Outcome measures: Microbial culture, plaque index, and gingival index. Statistical analysis: Paired t test and Kruskal Wallis test. Results: There was a significant reduction in mean Streptococcus mutans count, Lactobacillus count, plaque scores, and gingival scores in all four groups after the study. However, there was no significant difference found in percentage reduction of these variables between the four groups. Conclusion: These oils can be used as valuable preventive agents in maintaining and improving oral health in low socioeconomic status population. However, it is recommended that further research should be conducted in other populations with a larger sample and longer duration of follow-up period. PMID:25210256

Stability of dronabinol capsules when stored frozen, refrigerated, or at room temperature.

PubMed

Wempe, Michael F; Oldland, Alan; Stolpman, Nancy; Kiser, Tyree H

2016-07-15

Results of a study to determine the 90-day stability of dronabinol capsules stored under various temperature conditions are reported. High-performance liquid chromatography (HPLC) with ultraviolet (UV) detection was used to assess the stability of dronabinol capsules (synthetic delta-9-tetrahydrocannabinol [Δ9-THC] mixed with high-grade sesame oil and other inactive ingredients and encapsulated as soft gelatin capsules) that were frozen, refrigerated, or kept at room temperature for three months. The dronabinol capsules remained in the original foil-sealed blister packs until preparation for HPLC-UV assessment. The primary endpoint was the percentage of the initial Δ9-THC concentration remaining at multiple designated time points. The secondary aim was to perform forced-degradation studies under acidic conditions to demonstrate that the HPLC-UV method used was stability indicating. The appearance of the dronabinol capsules remained unaltered during frozen, cold, or room-temperature storage. Regardless of storage condition, the percentage of the initial Δ9-THC content remaining was greater than 97% for all evaluated samples at all time points over the three-month study. These experimental data indicate that the product packaging and the sesame oil used to formulate dronabinol capsules efficiently protect Δ9-THC from oxidative degradation to cannabinol; this suggests that pharmacies can store dronabinol capsules in nonrefrigerated automated dispensing systems, with a capsule expiration date of 90 days after removal from the refrigerator. Dronabinol capsules may be stored at room temperature in their original packaging for up to three months without compromising capsule appearance and with minimal reduction in Δ9-THC concentration. Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Plumbagin improves the efficacy of androgen deprivation therapy in prostate cancer: A pre-clinical study.

PubMed

Abedinpour, Parisa; Baron, Véronique T; Chrastina, Adrian; Rondeau, Gaelle; Pelayo, Jennifer; Welsh, John; Borgström, Per

2017-12-01

Plumbagin is a candidate drug for the treatment of prostate cancer. Previous observations indicated that it may improve the efficacy of androgen deprivation therapy (ADT). This study evaluates the effectiveness of treatment with combinations of plumbagin and alternative strategies for ADT in mouse models of prostate cancer to support its clinical use. Plumbagin was administered per oral in a new sesame oil formulation. Standard toxicology studies were performed in rats. For tumor growth studies, mouse prostate cancer cell spheroids were placed on top of grafted prostate tissue in a dorsal chamber and allowed to form tumors. Mice were separated in various treatment groups and tumor size was measured over time by intra-vital microscopy. Survival studies were done in mice after injection of prostate cancer cells in the prostate of male animals. Androgen receptor (AR) levels were analyzed by Western blot from prostate cancer cells treated with plumbagin. Plumbagin caused a decrease in AR levels in vitro. In mice, plumbagin at 1 mg/kg in sesame oil displayed low toxicity and caused a 50% tumor regression when combined with castration. The combination of plumbagin with various forms of chemical ADT including treatment with a GnRH receptor agonist, a GnRH receptor antagonist, or CYP17A1 inhibitors, outperformed ADT alone, increasing mouse survival compared to the standard regimen of castration alone. In contrast, the combination of plumbagin with AR antagonists, such as bicalutamide and enzalutamide, showed no improvement over AR antagonists alone. Thus, plumbagin is effective in combination with drugs that prevent the synthesis of testosterone or its conversion to dihydrotestosterone, but not with drugs that bind to AR. Plumbagin significantly improves the effect of ADT drugs currently used in the clinic, with few side effects in mice. © 2017 Wiley Periodicals, Inc.

DREAM/calsenilin/KChIP3 modulates strategy selection and estradiol-dependent learning and memory.

PubMed

Tunur, Tumay; Stelly, Claire E; Schrader, Laura Ann

2013-11-18

Downstream regulatory element antagonist modulator (DREAM)/calsenilin(C)/K⁺ channel interacting protein 3 (KChIP3) is a multifunctional Ca²⁺-binding protein highly expressed in the hippocampus that inhibits hippocampus-sensitive memory and synaptic plasticity in male mice. Initial studies in our lab suggested opposing effects of DR/C/K3 expression in female mice. Fluctuating hormones that occur during the estrous cycle may affect these results. In this study, we hypothesized that DR/C/K3 interacts with 17β-estradiol, the primary estrogen produced by the ovaries, to play a role in hippocampus function. We investigated the role of estradiol and DR/C/K3 in learning strategy in ovariectomized (OVX) female mice. OVX WT and DR/C/K3 knockout (KO) mice were given three injections of vehicle (sesame oil) or 17β-estradiol benzoate (0.25 mg in 100 mL sesame oil) 48, 24, and 2 h before training and testing. DR/C/K3 and estradiol had a time-dependent effect on strategy use in the female mice. Male KO mice exhibited enhanced place strategy relative to WT 24 h after pre-exposure. Fear memory formation was significantly reduced in intact female KO mice relative to intact WT mice, and OVX reduced fear memory formation in the WT, but had no effect in the KO mice. Long-term potentiation in hippocampus slices from female mice was enhanced by circulating ovarian hormones in both WT and DR/C/K3 KO mice. Paired-pulse depression was not affected by ovarian hormones but was reduced in DR/C/K3 KO mice. These results provide the first evidence that DR/C/K3 plays a timing-dependent role in estradiol regulation of learning, memory, and plasticity.

Superconducting magnetic Wollaston prism for neutron spin encoding

NASA Astrophysics Data System (ADS)

Li, F.; Parnell, S. R.; Hamilton, W. A.; Maranville, B. B.; Wang, T.; Semerad, R.; Baxter, D. V.; Cremer, J. T.; Pynn, R.

2014-05-01

A magnetic Wollaston prism can spatially split a polarized neutron beam into two beams with different neutron spin states, in a manner analogous to an optical Wollaston prism. Such a Wollaston prism can be used to encode the trajectory of neutrons into the Larmor phase associated with their spin degree of freedom. This encoding can be used for neutron phase-contrast radiography and in spin echo scattering angle measurement (SESAME). In this paper, we show that magnetic Wollaston prisms with highly uniform magnetic fields and low Larmor phase aberration can be constructed to preserve neutron polarization using high temperature superconducting (HTS) materials. The Meissner effect of HTS films is used to confine magnetic fields produced electromagnetically by current-carrying HTS tape wound on suitably shaped soft iron pole pieces. The device is cooled to ˜30 K by a closed cycle refrigerator, eliminating the need to replenish liquid cryogens and greatly simplifying operation and maintenance. A HTS film ensures that the magnetic field transition within the prism is sharp, well-defined, and planar due to the Meissner effect. The spin transport efficiency across the device was measured to be ˜98.5% independent of neutron wavelength and energizing current. The position-dependent Larmor phase of neutron spins was measured at the NIST Center for Neutron Research facility and found to agree well with detailed simulations. The phase varies linearly with horizontal position, as required, and the neutron beam shows little depolarization. Consequently, the device has advantages over existing devices with similar functionality and provides the capability for a large neutron beam (20 mm × 30 mm) and an increase in length scales accessible to SESAME to beyond 10 μm. With further improvements of the external coupling guide field in the prototype device, a larger neutron beam could be employed.

Effect of External Use of Sesame Oil in the Prevention of Chemotherapy-Induced Phlebitis

PubMed Central

Nekuzad, Nilufar; Ashke Torab, Tahereh; Mojab, Faraz; Alavi-Majd, Hamid; Azadeh, Payam; Ehtejab, Gholamreza

2012-01-01

Intravenous chemotherapy is an important mean for the treatment of cancers. Infusion phlebitis (Ph) is a common and acute complication of chemotherapy. The frequency of Ph is about 70% in patients undergoing chemotherapeutic management. It can induce the pain, increase the risk of thrombophlebitis, lead to incomplete follow-up, and thereby, affect the patient’s health status. Respecting the great importance of these issues, it is essential to prevent Ph. This study conducted to determine the effect of external use of Sesame Oil (SO) in the prevention of Ph. Sixty patients with colon or rectum cancer, who admitted for chemotherapeutic management, enrolled in clinical trial and were randomly divided into two equal groups: Control and Intervention. Ten drops of SO was applied twice a day for 14 days externally in intervention group, whereas the control group received nothing. Incidence and grade of Ph was measured in both groups. Data was analyzed through independent t-test, Χ2, Fisher’s exact test, Mann-Whitney, and Lagrange survival using SPSS 16. The incidence of Ph was 10% and 80% in intervention group and control group, respectively.There was a significant difference between two groups (p < 0.05). Ph was 8 times more frequent in control group (R R = 8; AR R = 70%). In addition, there was statistically significant difference between the grade and incidence of Ph with SO and control group (p < 0.05). According to these results, it seems that external use of SO is effective, safe and well-tolerated for prophylaxis from Ph. Therefore, it can be suggested as a selected prevention method for reducing the complication. PMID:24250538

Bacteriological quality of vegetables from organic and conventional production in different areas of Korea.

PubMed

Tango, Charles Nkufi; Choi, Na-Jung; Chung, Myung-Sub; Oh, Deog Hwan

2014-08-01

Foods grown in organic production systems have been described as representing an increased risk to public health compared with foods from conventional production. Leafy vegetables (spinach, romaine lettuce, and green sesame leaves) grown in organic and conventional systems were collected from various areas in Korea and examined using standard culture methods to compare the microbiological quality of the produce grown in the two agricultural systems. The 354 samples of these leafy vegetables were analyzed for levels of indicator bacteria (aerobic bacteria, coliforms, and Escherichia coli) and the prevalence of the pathogens Staphylococcus aureus, E. coli O157:H7, Listeria monocytogenes, Bacillus cereus, and Salmonella. Aerobic bacteria and coliforms were detected in all vegetable types, but nonpathogenic E. coli was below the limit of detection in all samples. B. cereus was the most prevalent pathogen, found on 7 (11.1%) of the 63 organic spinach samples. The prevalence of S. aureus was highest in organic sesame leaves; it was found on 5 (8.0%) of the 63 samples. The prevalence of L. monocytogenes was highest on organic romaine lettuce and spinach; it was found in 4 (6.4%) of 63 samples of each type of vegetable. E. coli O157:H7 found on only 1 (1.58%) of 55 conventional spinach samples. These results suggest that farming type at most only slightly affects the hygienic quality of leafy vegetables, and no effect was found for sample collection area. Salmonella was not isolated from any of the conventional or organic leafy vegetables. These results do not support the hypothesis that organic produce poses a substantially greater risk of pathogen contamination than does conventional produce.

Superconducting magnetic Wollaston prism for neutron spin encoding.

PubMed

Li, F; Parnell, S R; Hamilton, W A; Maranville, B B; Wang, T; Semerad, R; Baxter, D V; Cremer, J T; Pynn, R

2014-05-01

A magnetic Wollaston prism can spatially split a polarized neutron beam into two beams with different neutron spin states, in a manner analogous to an optical Wollaston prism. Such a Wollaston prism can be used to encode the trajectory of neutrons into the Larmor phase associated with their spin degree of freedom. This encoding can be used for neutron phase-contrast radiography and in spin echo scattering angle measurement (SESAME). In this paper, we show that magnetic Wollaston prisms with highly uniform magnetic fields and low Larmor phase aberration can be constructed to preserve neutron polarization using high temperature superconducting (HTS) materials. The Meissner effect of HTS films is used to confine magnetic fields produced electromagnetically by current-carrying HTS tape wound on suitably shaped soft iron pole pieces. The device is cooled to ~30 K by a closed cycle refrigerator, eliminating the need to replenish liquid cryogens and greatly simplifying operation and maintenance. A HTS film ensures that the magnetic field transition within the prism is sharp, well-defined, and planar due to the Meissner effect. The spin transport efficiency across the device was measured to be ~98.5% independent of neutron wavelength and energizing current. The position-dependent Larmor phase of neutron spins was measured at the NIST Center for Neutron Research facility and found to agree well with detailed simulations. The phase varies linearly with horizontal position, as required, and the neutron beam shows little depolarization. Consequently, the device has advantages over existing devices with similar functionality and provides the capability for a large neutron beam (20 mm × 30 mm) and an increase in length scales accessible to SESAME to beyond 10 μm. With further improvements of the external coupling guide field in the prototype device, a larger neutron beam could be employed.

An antiprogestin, CDB4124, blocks progesterone's attenuation of the negative effects of a mild stress on sexual behavior.

PubMed

Uphouse, Lynda; Hiegel, Cindy

2013-03-01

These experiments were designed to test the hypothesis that a progesterone receptor antagonist would block progesterone's ability to reduce the negative effects of a 5 min restraint on female rat sexual behavior. Ovariectomized Fischer rats were injected with 10 μg estradiol benzoate. Two days later, rats were injected subcutaneously (sc) with the progesterone receptor antagonist, CDB4124 (17α-acetoxy-21-methoxy-11β-[4-N,N-dimethyaminopheny]-19-norpregna-4,9-dione-3,20-dione) (60 mg/kg), or vehicle (20% DMSO+propylene glycol). One hour later, rats were injected sc with 500 μg progesterone or vehicle (sesame seed oil). Rats were assigned to one of three different treatment conditions: (1) (ECV) estradiol benzoate, CDB4124, sesame seed oil vehicle, (2) (ECP) estradiol benzoate, CDB4124, progesterone, and (3) (EVP) estradiol benzoate, DMSO/propylene glycol vehicle, progesterone. That afternoon sexual behavior was examined before and after a 5 min restraint experience. Before restraint, lordosis behavior was comparable across treatment conditions but only progesterone-treated rats exhibited proceptive behavior. CDB4124 did not block progesterone's induction of proceptivity. However, after restraint, CDB4124 attenuated the positive effects of progesterone on all sexual behaviors examined. The restraint experience inhibited sexual behavior in rats treated with estradiol benzoate and CDB4124 and in rats treated with estradiol benzoate, CDB4124, and progesterone but not in rats given estradiol benzoate and progesterone without CDB4124. These findings are consistent with the hypothesis that progesterone receptors mediate progesterone's ability to reduce the negative sexual behavioral effects of a mild stressor. Copyright © 2012 Elsevier B.V. All rights reserved.

Compact ultrafast semiconductor disk laser: targeting GFP based nonlinear applications in living organisms

PubMed Central

Aviles-Espinosa, Rodrigo; Filippidis, George; Hamilton, Craig; Malcolm, Graeme; Weingarten, Kurt J.; Südmeyer, Thomas; Barbarin, Yohan; Keller, Ursula; Santos, Susana I.C.O; Artigas, David; Loza-Alvarez, Pablo

2011-01-01

We present a portable ultrafast Semiconductor Disk Laser (SDL) (or vertical extended cavity surface emitting laser—VECSELs), to be used for nonlinear microscopy. The SDL is modelocked using a quantum-dot semiconductor saturable absorber mirror (SESAM), delivering an average output power of 287 mW, with 1.5 ps pulses at 500 MHz and a central wavelength of 965 nm. Specifically, despite the fact of having long pulses and high repetition rates, we demonstrate the potential of this laser for Two-Photon Excited Fluorescence (TPEF) imaging of in vivo Caenorhabditis elegans (C. elegans) expressing Green Fluorescent Protein (GFP) in a set of neuronal processes and cell bodies. Efficient TPEF imaging is achieved due to the fact that this wavelength matches the peak of the two-photon action cross section of this widely used fluorescent marker. The SDL extended versatility is shown by presenting Second Harmonic Generation images of pharynx, uterus, body wall muscles and its potential to be used to excite other different commercial dyes. Importantly this non-expensive, turn-key, compact laser system could be used as a platform to develop portable nonlinear bio-imaging devices. PMID:21483599

Value addition of vegetable wastes by solid-state fermentation using Aspergillus niger for use in aquafeed industry.

PubMed

Rajesh, N; Imelda-Joseph; Raj, R Paul

2010-11-01

Vegetable waste typically has high moisture content and high levels of protein, vitamins and minerals. Its value as an agricultural feed can be enhanced through solid-state fermentation (SSF). Two experiments were conducted to evaluate the nutritional status of the products derived by SSF of a mixture of dried vegetable waste powder and oil cake mixture (soybean flour, wheat flour, groundnut oil cake and sesame oil cake at 4:3:2:1 ratio) using fungi Aspergillus niger S(1)4, a mangrove isolate, and A. niger NCIM 616. Fermentation was carried out for 9 days at 35% moisture level and neutral pH. Significant (p<0.05) increase in crude protein and amino acids were obtained in both the trials. The crude fat and crude fibre content showed significant reduction at the end of fermentation. Nitrogen free extract (NFE) showed a gradual decrease during the fermentation process. The results of the study suggest that the fermented product obtained on days 6 and 9 in case of A. niger S(1)4 and A. niger NCIM 616 respectively contained the highest levels of crude protein. Copyright © 2010 Elsevier Ltd. All rights reserved.

GLC analysis of poison ivy and poison oak urushiol components in vegetable oil preparations.

PubMed

Elsohly, M A; Turner, C E

1980-05-01

A procedure is described for the analysis of urushiol content of pharmaceutical preparations containing extracts of poison ivy (Toxicodendron radicans) and poison oak (T. diversilobum) in vegetable oils. The procedure involves extraction of the urushiols from the oily solutions using 90% methanol in water followed by GLC analysis of the extracts. Recoveries of both poison ivy and poison oak urushiols from solutions in corn oil, olive oil, sesame seed oil, and cottonseed oil were calculated. Correlation coefficients (r2) ranged from 0.97 to 1.00, and the coefficients of variations ranged from 3.08 to 7.90%.

A journey into the imaginary of Sicilian pastry.

PubMed

Tarantino, Maria; Terziani, Sabina

2010-01-01

This article is an anthropological archeology of Sicilian confectionery, from the prehistoric-like assemblage of sesame seeds and honey (giurgiulena) to the extravagant gelato di campagna and the baroque-rustic cassata. Sweets are analyzed as architectural constructions that rely on newly discovered ingredients and techniques to create edible edifices that amazed the eye as much as the palate. They emerge from their historical and social context and affirm themselves as moments of innovation in the culinary art. On a deeper level, the art of pasticceri bears the marks of an existential quest that constantly redefines man's symbolic relation to the forces and contrasts of life.

A comparative mass spectrometric study of fatty acids and metals in some seed extracts.

PubMed

Suvar, Sonia Niculina; Bleiziffer, R; Podea, P; Iordache, A; Voica, C; Zgavarogea, R; Culea, M

A major cause of cardiovascular diseases and cancer is diet content, so the optimization of micronutrients in food is very important. Omega-3 fatty acids supplementation for patients had beneficial effects on subjective global assessment score and metabolic profiles. Fatty acids content and the metal ions in different seeds (e.g. linseed, poppy, grape, hemp, nuts, pumpkin, sesame, watermelon, chia) recommended as food supplements, purchased on the Romanian market, were compared. Gas chromatography coupled to mass spectrometry (GC-MS) was used as an excellent technique for fatty acids identification and quantitation, and inductively coupled plasma mass spectrometer (ICP-MS) for analytical measurements of metals.

Passively mode-locked diode-pumped Tm3+:YLF laser emitting at 1.91 µm using a GaAs-based SESAM

NASA Astrophysics Data System (ADS)

Tyazhev, A.; Soulard, R.; Godin, T.; Paris, M.; Brasse, G.; Doualan, J.-L.; Braud, A.; Moncorgé, R.; Laroche, M.; Camy, P.; Hideur, A.

2018-04-01

We report on a diode-pumped Tm:YLF laser passively mode-locked with an InGaAs saturable absorber. The laser emits a train of 31 ps pulses at a wavelength of 1.91 µm with a repetition rate of 94 MHz and a maximum average power of 95 mW. A sustained and robust mode-locking with a signal-to-noise ratio of ~70 dB is obtained even at high relative air humidity, making this system attractive for applications requiring ultra-short pulses in the spectral window just below 2 µm.

High power Yb:CALGO ultrafast regenerative amplifier for industrial application

NASA Astrophysics Data System (ADS)

Caracciolo, E.; Guandalini, A.; Pirzio, F.; Kemnitzer, M.; Kienle, F.; Agnesi, A.; Aus der Au, J.

2017-02-01

We present a high-power, single-crystal based, Yb:CALGO regenerative amplifier. The system delivers more than 50 W output power in continuous-wave regime, with diffraction limited beam quality. In Q-switching regime the spectrum is centered at 1043 nm and is 11 nm wide. In regenerative amplification experiments we achieved 34 W at 500 kHz with 12.7 nm FWHM wide spectra centered at 1044 nm seeding with a broadly tunable, single-prism SESAM mode-locked Yb:CALGO laser providing 9 nm wide spectra at 1049 nm. Pulse duration after compression was 140 fs, with excellent beam quality (M2 < 1.25).

Different evolution dynamics of vector solitons depending on their polarization states

NASA Astrophysics Data System (ADS)

Chen, Wei-Cheng; Chen, Guo-Jie

2014-03-01

There are three types of temporal evolution dynamics of vector solitons observed in a ring fiber laser with a semiconductor saturable absorption mirror (SESAM) as a mode-locker. It is found that the polarization property of vector solitons is an important factor for achieving different evolution dynamics. The vector soliton with a uniform polarization state across the whole pulse profile and zero polarization extinction ratio operates at a fundamental repetition rate with a single pulse profile. The elliptically polarized vector soliton with a larger polarization extinction ratio exhibits a harmonic pulse train. The soliton bunching with multi-peak structures exists between the above two states and shows elliptical polarization with a small polarization extinction ratio.

Passive Q-switching of ˜2.7 µm Er:Lu2O3 ceramic laser with a semiconductor saturable absorber mirror

NASA Astrophysics Data System (ADS)

Ren, Xiaojing; Shen, Deyuan; Zhang, Jian; Tang, Dingyuan

2018-02-01

We demonstrate the passively Q-switched operation of an Er:Lu2O3 ceramic laser at ˜2.7 µm for the first time, to the best of our knowledge. By using a semiconductor saturable absorber mirror (SESAM), stable pulse trains with a repetition rate of 20-33.3 kHz are produced in a compacted v-shaped resonator. The pulse duration (FWHM), pulse energy, and peak power are 660 ns, 1.8 µJ, and ˜2.73 W, respectively, at 33.3 kHz repetition rate. Prospects for further improvements in terms of laser performances are discussed.

Astronomy and international science diplomacy

NASA Astrophysics Data System (ADS)

Madsen, Claus

2015-08-01

Since WW2, science has played an important, if sometimes overlooked, role in international relations and international diplomacy. The founding of CERN in 1954 and the more recent establishment of SESAME as a major research infrastructure in the Middle East are examples of this. The IAU has played its own role in the field of science diplomacy ranging from quietly fostering interaction between the antagonists of the Cold War period to the world-uniting initiative of the International Year of Astronomy. Beyond the IAU, yet still with clear links to it, we have seen ESO as an example as well as the more recent one of SKA as a vehicle for development and for strengthening international relations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen Weicheng; Chen Guojie; Han Dingan

A fibre laser with a SESAM as a passive mode-locker is constructed for obtaining a vector soliton with the Kelly sidebands. The analysis of the peculiarities of the sidebands shows that the polarisation states are nonuniform across the entire pulse spectral profile from the leading edge to the trailing edge. Polarisation filtering effect is proposed to obtain a vector soliton with a uniform polarisation state. It is shown that during the polarisation filtering by a polariser incorporated into the laser cavity, the spectral width of the vector solitons gradually broadens and the pulse power decreases. It is found that atmore » a maximum spectral width and a minimum pulse power, vector solitons with a uniform polarisation state are generated. (nonlinear optical phenomena)« less

Multiphase aluminum equations of state via density functional theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjostrom, Travis; Crockett, Scott; Rudin, Sven

2016-10-03

We have performed density functional theory (DFT) based calculations for aluminum in extreme conditions of both pressure and temperature, up to five times compressed ambient density, and over 1 000 000 K in temperature. In order to cover such a domain, DFT methods including phonon calculations, quantum molecular dynamics, and orbital-free DFT are employed. Our results are then used to construct a SESAME equation of state for the aluminum 1100 alloy, encompassing the fcc, hcp, and bcc solid phases as well as the liquid regime. We also provide extensive comparison with experiment, and based on this we also provide amore » slightly modified equation of state for the aluminum 6061 alloy.« less

Open Sesame: treasure in store-operated calcium entry pathway for cancer therapy

PubMed Central

Zui, PAN; JianJie, MA

2016-01-01

Store-operated Ca2+ entry (SOCE) controls intracellular Ca2+ homeostasis and regulates a wide range of cellular events including proliferation, migration and invasion. The discovery of STIM proteins as Ca2+ sensors and Orai proteins as Ca2+ channel pore forming units provided molecular tools to understand the physiological function of SOCE. Many studies have revealed the pathophysiological roles of Orai and STIM in tumor cells. This review focuses on recent advances in SOCE and its contribution to tumorigenesis. Altered Orai and/or STIM functions may serve as biomarkers for cancer prognosis, and targeting the SOCE pathway may provide a novel means for cancer treatment. PMID:25481035

Carrier-envelope offset frequency stabilization of an ultrafast semiconductor laser

NASA Astrophysics Data System (ADS)

Jornod, Nayara; Gürel, Kutan; Wittwer, Valentin J.; Brochard, Pierre; Hakobyan, Sargis; Schilt, Stéphane; Waldburger, Dominik; Keller, Ursula; Südmeyer, Thomas

2018-02-01

We present the self-referenced stabilization of the carrier-envelope offset (CEO) frequency of a semiconductor disk laser. The laser is a SESAM-modelocked VECSEL emitting at a wavelength of 1034 nm with a repetition frequency of 1.8 GHz. The 270-fs pulses are amplified to 3 W and compressed to 120 fs for the generation of a coherent octavespanning supercontinuum spectrum. A quasi-common-path f-to-2f interferometer enables the detection of the CEO beat with a signal-to-noise ratio of 30 dB sufficient for its frequency stabilization. The CEO frequency is phase-locked to an external reference with a feedback signal applied to the pump current.

A case study of the effects of random errors in rawinsonde data on computations of ageostrophic winds

NASA Technical Reports Server (NTRS)

Moore, J. T.

1985-01-01

Data input for the AVE-SESAME I experiment are utilized to describe the effects of random errors in rawinsonde data on the computation of ageostrophic winds. Computer-generated random errors for wind direction and speed and temperature are introduced into the station soundings at 25 mb intervals from which isentropic data sets are created. Except for the isallobaric and the local wind tendency, all winds are computed for Apr. 10, 1979 at 2000 GMT. Divergence fields reveal that the isallobaric and inertial-geostrophic-advective divergences are less affected by rawinsonde random errors than the divergence of the local wind tendency or inertial-advective winds.

STUDY ON DIGESTION AND ABSORPTION FOLLOWING GASTROINTESTINAL SURGERIES WITH AN APPLICATION OF RADIOACTIVE ISOTOPES (WITH SPECIAL EMPHASIS ON CASES OF GASTRIC SURGERIES)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakayama, K.; Ohtsuka, A.; Kuraishi, T.

1959-10-31

The digestion and absorption of proteins and fats were studied in patients following radical surgery for carcinoma of the digestive tract. Proteins labeled with phosphorus-32 were synthesized in vivo using goat milk, hen eggs, and intestinal membrane and liver of a dog. Protein labeled with sulfur-35 was obtained from yeast. Amino acid was labeled with carbon-14. Sesame oil labeled with iodine-131 was used as an indicator of fat absorption. The indicators were given orally in test meals. Blood level and fecal and urinary excretion were measured. Procedures are outlined for preparing the labeled indicators. Data are tabulated. (C.H.)

Single-laboratory validation of a GC/MS method for the determination of 27 polycyclic aromatic hydrocarbons (PAHs) in oils and fats.

PubMed

Rose, M; White, S; Macarthur, R; Petch, R G; Holland, J; Damant, A P

2007-06-01

A protocol for the measurement of 27 polycyclic aromatic hydrocarbons (PAHs) in vegetable oils by GC/MS has undergone single-laboratory validation. PAHs were measured in three oils (olive pomace, sunflower and coconut oil). Five samples of each oil (one unfortified, and four fortified at concentrations between 2 and 50 microg kg(-1)) were analysed in replicate (four times in separate runs). Two samples (one unfortified and one fortified at 2 microg kg(-1)) of five oils (virgin olive oil, grapeseed oil, toasted sesame oil, olive margarine and palm oil) were also analysed. The validation included an assessment of measurement bias from the results of 120 measurements of a certified reference material (coconut oil BCR CRM458 certified for six PAHs). The method is capable of reliably detecting 26 out of 27 PAHs, at concentration <2 microg kg(-1) which is the European Union maximum limit for benzo[a]pyrene, in vegetable oils, olive pomace oil, sunflower oil and coconut oil. Quantitative results were obtained that are fit for purpose for concentrations from <2 to 50 microg kg(-1) for 24 out of 27 PAHs in olive pomace oil, sunflower oil and coconut oil. The reliable detection of 2 microg kg(-1) of PAHs in five additional oils (virgin olive oil, grapeseed oil, toasted sesame oil, olive margarine and palm oil) has been demonstrated. The method failed to produce fit-for-purpose results for the measurement of dibenzo[a,h]pyrene, anthanthrene and cyclopenta[c,d]pyrene. The reason for the failure was the large variation in results. The likely cause was the lack of availability of (13)C isotope internal standards for these PAHs at the time of the study. The protocol has been shown to be fit-for-purpose and is suitable for formal validation by inter-laboratory collaborative study.

Effects of Ayurvedic Oil-Dripping Treatment with Sesame Oil vs. with Warm Water on Sleep: A Randomized Single-Blinded Crossover Pilot Study

PubMed Central

Yorifuji, Takashi; Tsuda, Toshihide; Doi, Hiroyuki

2016-01-01

Abstract Objectives: Ayurvedic oil-dripping treatment (Shirodhara) is often used for treating sleep problems. However, few properly designed studies have been conducted, and the quantitative effect of Shirodhara is unclear. This study sought to quantitatively evaluate the effect of sesame oil Shirodhara (SOS) against warm water Shirodhara (WWS) on improving sleep quality and quality of life (QOL) among persons reporting sleep problems. Methods: This randomized, single-blinded, crossover study recruited 20 participants. Each participant received seven 30-minute sessions within 2 weeks with either liquid. The washout period was at least 2 months. The Shirodhara procedure was conducted by a robotic oil-drip system. The outcomes were assessed by the Pittsburgh Sleep Quality Index (PSQI) for sleep quality, Epworth Sleepiness Scale (ESS) for daytime sleepiness, World Health Organization Quality of Life 26 (WHO-QOL26) for QOL, and a sleep monitor instrument for objective sleep measures. Changes between baseline and follow-up periods were compared between the two types of Shirodhara. Analysis was performed with generalized estimating equations. Results: Of 20 participants, 15 completed the study. SOS improved sleep quality, as measured by PSQI. The SOS score was 1.83 points lower (95% confidence interval [CI], −3.37 to −0.30) at 2-week follow-up and 1.73 points lower (95% CI, −3.84 to 0.38) than WWS at 6-week follow-up. Although marginally significant, SOS also improved QOL by 0.22 points at 2-week follow-up and 0.19 points at 6-week follow-up compared with WWS. After SOS, no beneficial effects were observed on daytime sleepiness or objective sleep measures. Conclusions: This pilot study demonstrated that SOS may be a safe potential treatment to improve sleep quality and QOL in persons with sleep problems. PMID:26669255

Superconducting magnetic Wollaston prism for neutron spin encoding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, F., E-mail: fankli@indiana.edu; Parnell, S. R.; Wang, T.

2014-05-15

A magnetic Wollaston prism can spatially split a polarized neutron beam into two beams with different neutron spin states, in a manner analogous to an optical Wollaston prism. Such a Wollaston prism can be used to encode the trajectory of neutrons into the Larmor phase associated with their spin degree of freedom. This encoding can be used for neutron phase-contrast radiography and in spin echo scattering angle measurement (SESAME). In this paper, we show that magnetic Wollaston prisms with highly uniform magnetic fields and low Larmor phase aberration can be constructed to preserve neutron polarization using high temperature superconducting (HTS)more » materials. The Meissner effect of HTS films is used to confine magnetic fields produced electromagnetically by current-carrying HTS tape wound on suitably shaped soft iron pole pieces. The device is cooled to ∼30 K by a closed cycle refrigerator, eliminating the need to replenish liquid cryogens and greatly simplifying operation and maintenance. A HTS film ensures that the magnetic field transition within the prism is sharp, well-defined, and planar due to the Meissner effect. The spin transport efficiency across the device was measured to be ∼98.5% independent of neutron wavelength and energizing current. The position-dependent Larmor phase of neutron spins was measured at the NIST Center for Neutron Research facility and found to agree well with detailed simulations. The phase varies linearly with horizontal position, as required, and the neutron beam shows little depolarization. Consequently, the device has advantages over existing devices with similar functionality and provides the capability for a large neutron beam (20 mm × 30 mm) and an increase in length scales accessible to SESAME to beyond 10 μm. With further improvements of the external coupling guide field in the prototype device, a larger neutron beam could be employed.« less

Antioxidative effects of fermented sesame sauce against hydrogen peroxide-induced oxidative damage in LLC-PK1 porcine renal tubule cells

PubMed Central

Song, Jia-Le; Choi, Jung-Ho; Seo, Jae-Hoon; Kil, Jeung-Ha

2014-01-01

BACKGROUND/OBJECTIVES This study was performed to investigate the in vitro antioxidant and cytoprotective effects of fermented sesame sauce (FSeS) against hydrogen peroxide (H2O2)-induced oxidative damage in renal proximal tubule LLC-PK1 cells. MATERIALS/METHODS 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical (•OH), and H2O2 scavenging assay was used to evaluate the in vitro antioxidant activity of FSeS. To investigate the cytoprotective effect of FSeS against H2O2-induced oxidative damage in LLC-PK1 cells, the cellular levels of reactive oxygen species (ROS), lipid peroxidation, and endogenous antioxidant enzymes including catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GSH-px) were measured. RESULTS The ability of FSeS to scavenge DPPH, •OH and H2O2 was greater than that of FSS and AHSS. FSeS also significantly inhibited H2O2-induced (500 µM) oxidative damage in the LLC-PK1 cells compared to FSS and AHSS (P < 0.05). Following treatment with 100 µg/mL of FSeS and FSS to prevent H2O2-induced oxidation, cell viability increased from 56.7% (control) to 83.7% and 75.6%, respectively. However, AHSS was not able to reduce H2O2-induced cell damage (viability of the AHSS-treated cells was 54.6%). FSeS more effectively suppressed H2O2-induced ROS generation and lipid peroxidation compared to FSS and AHSS (P < 0.05). Compared to the other sauces, FSeS also significantly increased cellular CAT, SOD, and GSH-px activities and mRNA expression (P < 0.05). CONCULUSIONS These results from the present study suggest that FSeS is an effective radical scavenger and protects against H2O2-induced oxidative damage in LLC-PK1 cells by reducing ROS levels, inhibiting lipid peroxidation, and stimulating antioxidant enzyme activity. PMID:24741396

Chemical composition and efficacy of some selected plant oils against Pediculus humanus capitis in vitro.

PubMed

Yones, Doaa A; Bakir, Hanaa Y; Bayoumi, Soad A L

2016-08-01

Natural compounds have been suggested as alternative sources for pediculosis capitis control. We aimed to investigate the chemical composition and evaluate the pediculicidal activity of spearmint, clove, cassia, thyme, eucalyptus, and anise essential oils in addition to sesame oil against human head lice in vitro. A filter paper contact bioassay method was used by applying 0.25 and 0.5 mg/cm(2) of each tested oil to filter paper in Petri dishes with 15 females head lice and another with ten nits. The lice mortalities were reported every 5 min for 180 min. The percentage of inhibition of hatch (PIH) was used to calculate ovicidal activity by daily microscopic inspections 5 days after the hatching of controls. Comparison with the widely used pediculicide (malathion) was performed. The most effective essential oil was spearmint followed by cassia and clove with KT50 values of 4.06, 7.62, and 12.12 at 0.5 mg/cm(2) and 8.84, 11.38, and 19.73 at 0.25 mg/cm(2), respectively. Thyme, eucalyptus, and anise were also effective adulticides with KT50 values of 18.61, 32.65, and 37.34 at 0.5 mg/cm(2) and 29.92, 43.16, and 45.37 at 0.25 mg/cm(2), respectively. Essential oils were also successful in inhibiting nymph emergence. Spearmint oil was the most effective, with a complete inhibition of emergence at 0.5 mg/cm(2). Sesame fixed oil did not show any adulticidal or ovicidal activity against head lice in vitro. The observed insecticidal activity was comparable to malathion. The results herein described the effectiveness of these essential oils as potential pediculicides for head lice control. Incorporation of essential oils in pediculicide formulations needs proper formulation and clinical trials.

Simultaneous Determination of Iron, Copper and Cobalt in Food Samples by CCD-diode Array Detection-Flow Injection Analysis with Partial Least Squares Calibration Model

NASA Astrophysics Data System (ADS)

Mi, Jiaping; Li, Yuanqian; Zhou, Xiaoli; Zheng, Bo; Zhou, Ying

2006-01-01

A flow injection-CCD diode array detection spectrophotometry with partial least squares (PLS) program for simultaneous determination of iron, copper and cobalt in food samples has been established. The method was based on the chromogenic reaction of the three metal ions and 2- (5-Bromo-2-pyridylazo)-5-diethylaminophenol, 5-Br-PADAP in acetic acid - sodium acetate buffer solution (pH5) with Triton X-100 and ascorbic acid. The overlapped spectra of the colored complexes were collected by charge-coupled device (CCD) - diode array detector and the multi-wavelength absorbance data was processed using partial least squares (PLS) algorithm. Optimum reaction conditions and parameters of flow injection analysis were investigated. The samples of tea, sesame, laver, millet, cornmeal, mung bean and soybean powder were determined by the proposed method. The average recoveries of spiked samples were 91.80%~100.9% for Iron, 92.50%~108.0% for Copper, 93.00%~110.5% for Cobalt, respectively with relative standard deviation (R.S.D) of 1.1%~12.1%. The sampling rate is 45 samples h-1. The determination results of the food samples were in good agreement between the proposed method and ICP-AES.

Exploratory study on the ayurvedic therapeutic management of cerebral palsy in children at a tertiary care hospital of karnataka, India.

PubMed

Shailaja, U; Rao, Prasanna N; Debnath, Parikshit; Adhikari, Anjan

2014-01-01

Cerebral palsy (CP) is the leading cause of childhood disability affecting cognitive function and developments in approximately 1.5 to 3 cases per 1000 live births. Based on Ayurvedic therapeutic principles, CP patients were subjected to Abhyanga (massage) with Moorchita Tila Taila (processed sesame oil) and Svedana (fomentation) with Shastikashali Pinda Sveda (fomentation with bolus of drugs prepared with boiled rice). Study group received Mustadi Rajayapana Basti (enema with herbal decoction) and Baladi Yoga (a poly-herbo-mineral formulation), while the placebo group received Godhuma Vati (tablet prepared with wheat powder) and saline water as enema. Treatment with Mustadi Rajayapana Basti and Baladi Yoga improved the activities of daily life by 8.79%, gross motor functions by 19.76%, and fine motor functions 15.05%, and mental functions like memory retention got improved by 15.43%. The placebo group showed an improvement of 0.21% in daily life activities, 2.8% in gross motor, and 2.4% in fine motor functions. Mustadi Rajayapana Basti and Baladi Yoga proved to be more supportive in improving the motor activities and gross behavioral pattern. Further clinical trials are required to evaluate and validate the maximum effect of the combination therapy in a large sample with repetition of the courses for longer duration.

Exploratory Study on the Ayurvedic Therapeutic Management of Cerebral Palsy in Children at a Tertiary Care Hospital of Karnataka, India

PubMed Central

Shailaja, U; Rao, Prasanna N.; Debnath, Parikshit; Adhikari, Anjan

2014-01-01

Cerebral palsy (CP) is the leading cause of childhood disability affecting cognitive function and developments in approximately 1.5 to 3 cases per 1000 live births. Based on Ayurvedic therapeutic principles, CP patients were subjected to Abhyanga (massage) with Moorchita Tila Taila (processed sesame oil) and Svedana (fomentation) with Shastikashali Pinda Sveda (fomentation with bolus of drugs prepared with boiled rice). Study group received Mustadi Rajayapana Basti (enema with herbal decoction) and Baladi Yoga (a poly-herbo-mineral formulation), while the placebo group received Godhuma Vati (tablet prepared with wheat powder) and saline water as enema. Treatment with Mustadi Rajayapana Basti and Baladi Yoga improved the activities of daily life by 8.79%, gross motor functions by 19.76%, and fine motor functions 15.05%, and mental functions like memory retention got improved by 15.43%. The placebo group showed an improvement of 0.21% in daily life activities, 2.8% in gross motor, and 2.4% in fine motor functions. Mustadi Rajayapana Basti and Baladi Yoga proved to be more supportive in improving the motor activities and gross behavioral pattern. Further clinical trials are required to evaluate and validate the maximum effect of the combination therapy in a large sample with repetition of the courses for longer duration. PMID:24872933

Prediction of Shock-Induced Cavitation in Water

NASA Astrophysics Data System (ADS)

Brundage, Aaron

2013-06-01

Fluid-structure interaction problems that require estimating the response of thin structures within fluids to shock loading has wide applicability. For example, these problems may include underwater explosions and the dynamic response of ships and submarines; and biological applications such as Traumatic Brain Injury (TBI) and wound ballistics. In all of these applications the process of cavitation, where small cavities with dissolved gases or vapor are formed as the local pressure drops below the vapor pressure due to shock hydrodynamics, can cause significant damage to the surrounding thin structures or membranes if these bubbles collapse, generating additional shock loading. Hence, a two-phase equation of state (EOS) with three distinct regions of compression, expansion, and tension was developed to model shock-induced cavitation. This EOS was evaluated by comparing data from pressure and temperature shock Hugoniot measurements for water up to 400 kbar, and data from ultrasonic pressure measurements in tension to -0.3 kbar, to simulated responses from CTH, an Eulerian, finite volume shock code. The new EOS model showed significant improvement over pre-existing CTH models such as the SESAME EOS for capturing cavitation. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy/NNSA under contract DE-AC04-94AL85000.

Mycotoxins in spices and herbs-An update.

PubMed

Kabak, Bulent; Dobson, Alan D W

2017-01-02

Spices and herbs have been used since ancient times as flavor and aroma enhancers, colorants, preservatives, and traditional medicines. There are more than 30 spices and herbs of global economic and culinary importance. Among the spices, black pepper, capsicums, cumin, cinnamon, nutmeg, ginger, turmeric, saffron, coriander, cloves, dill, mint, thyme, sesame seed, mustard seed, and curry powder are the most popular spices worldwide. In addition to their culinary uses, a number of functional properties of aromatic herbs and spices are also well described in the scientific literature. However, spices and herbs cultivated mainly in tropic and subtropic areas can be exposed to contamination with toxigenic fungi and subsequently mycotoxins. This review provides an overview on the mycotoxin risk in widely consumed spices and aromatic herbs.

Ceramic planar waveguide laser of non-aqueous tape casting fabricated YAG/Yb:YAG/YAG

PubMed Central

Wang, Chao; Li, Wenxue; Yang, Chao; Bai, Dongbi; Li, Jiang; Ge, Lin; Pan, Yubai; Zeng, Heping

2016-01-01

Ceramic YAG/Yb:YAG/YAG planar waveguide lasers were realized on continuous-wave and mode-locked operations. The straight waveguide, fabricated by non-aqueous tape casting and solid state reactive sintering, enabled highly efficient diode-pumped waveguide continuous-wave laser with the slope efficiency of 66% and average output power of more than 3 W. The influence of the waveguide structure on the wavelength tunability was also experimentally investiccgated with a dispersive prism. Passively mode-locked operation of the ceramic waveguide laser was achieved by using a semiconductor saturable absorber mirror (SESAM), output 2.95 ps pulses with maximum power of 385 mW at the central wavelength of 1030 nm. PMID:27535577

Agaricus bisporus production on substrates pasteurized by self-heating.

PubMed

Colmenares-Cruz, Stephania; Sánchez, José E; Valle-Mora, Javier

2017-12-01

The aim of this work was to determine if the self-heating pasteurization procedure is technically applicable to the cultivation of Agaricus bisporus. Firstly the substrates alone (corncob, Pangola grass and a mixture of both ingredients with wood shavings) were tested. Two supplementation trials were then undertaken using soybean, wheat bran, sheep manure, sesame seed, black bean and chia. Highest production values (BE = 176.3% and Y = 26.6 kg/m 2 ) were obtained using a 9% supplement, with a formula consisting of 25% each of soybean, black bean, wheat bran and chia, added at spawning and at casing. These results were comparable to those obtained with the Phase II compost traditionally used for A. bisporus cultivation.

Essential oil-loaded lipid nanoparticles for wound healing.

PubMed

Saporito, Francesca; Sandri, Giuseppina; Bonferoni, Maria Cristina; Rossi, Silvia; Boselli, Cinzia; Icaro Cornaglia, Antonia; Mannucci, Barbara; Grisoli, Pietro; Vigani, Barbara; Ferrari, Franca

2018-01-01

Chronic wounds and severe burns are diseases responsible for severe morbidity and even death. Wound repair is a crucial process and tissue regeneration enhancement and infection prevention are key factors to minimize pain, discomfort, and scar formation. The aim of this work was the development of lipid nanoparticles (solid lipid nanoparticles and nanostructured lipid carriers [NLC]), to be loaded with eucalyptus or rosemary essential oils and to be used, as medical devices, to enhance healing of skin wounds. Lipid nanoparticles were based on natural lipids: cocoa butter, as solid lipid, and olive oil or sesame oil, as liquid lipids. Lecithin was chosen as surfactant to stabilize nanoparticles and to prevent their aggregation. The systems were prepared by high shear homogenization followed by ultrasound application. Nanoparticles were characterized for physical-chemical properties, bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward normal human dermal fibroblasts. Antimicrobial activity of nanoparticles was evaluated against two reference microbial strains, one of Staphylococcus aureus , the other of Streptococcus pyogenes . Finally, the capability of nanoparticles to promote wound healing in vivo was evaluated on a rat burn model. NLC based on olive oil and loaded with eucalyptus oil showed appropriate physical-chemical properties, good bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward fibroblasts, associated to antimicrobial properties. Moreover, the in vivo results evidenced the capability of these NLC to enhance the healing process. Olive oil, which is characterized by a high content of oleic acid, proved to exert a synergic effect with eucalyptus oil with respect to antimicrobial activity and wound repair promotion.

Essential oil-loaded lipid nanoparticles for wound healing

PubMed Central

Saporito, Francesca; Sandri, Giuseppina; Bonferoni, Maria Cristina; Rossi, Silvia; Boselli, Cinzia; Icaro Cornaglia, Antonia; Mannucci, Barbara; Grisoli, Pietro; Vigani, Barbara; Ferrari, Franca

2018-01-01

Chronic wounds and severe burns are diseases responsible for severe morbidity and even death. Wound repair is a crucial process and tissue regeneration enhancement and infection prevention are key factors to minimize pain, discomfort, and scar formation. The aim of this work was the development of lipid nanoparticles (solid lipid nanoparticles and nanostructured lipid carriers [NLC]), to be loaded with eucalyptus or rosemary essential oils and to be used, as medical devices, to enhance healing of skin wounds. Lipid nanoparticles were based on natural lipids: cocoa butter, as solid lipid, and olive oil or sesame oil, as liquid lipids. Lecithin was chosen as surfactant to stabilize nanoparticles and to prevent their aggregation. The systems were prepared by high shear homogenization followed by ultrasound application. Nanoparticles were characterized for physical–chemical properties, bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward normal human dermal fibroblasts. Antimicrobial activity of nanoparticles was evaluated against two reference microbial strains, one of Staphylococcus aureus, the other of Streptococcus pyogenes. Finally, the capability of nanoparticles to promote wound healing in vivo was evaluated on a rat burn model. NLC based on olive oil and loaded with eucalyptus oil showed appropriate physical–chemical properties, good bioadhesion, cytocompatibility, in vitro proliferation enhancement, and wound healing properties toward fibroblasts, associated to antimicrobial properties. Moreover, the in vivo results evidenced the capability of these NLC to enhance the healing process. Olive oil, which is characterized by a high content of oleic acid, proved to exert a synergic effect with eucalyptus oil with respect to antimicrobial activity and wound repair promotion. PMID:29343956

The effect of wind and moisture gradients on the arbitrary assignment of cloud motions to a vertical coordinate system in two Sesame cases

NASA Technical Reports Server (NTRS)

Peslen, C. A.; Koch, S. E.; Uccellini, L. W.

1984-01-01

Satellite-derived cloud motion 'wind' vectors (CMV) are increasingly used in mesoscale and in global analyses, and questions have been raised regarding the uncertainty of the level assignment for the CMV. One of two major problems in selecting a level for the CMV is related to uncertainties in assigning the motion vector to either the cloud top or base. The second problem is related to the inability to transfer the 'wind' derived from the CMV at individually specified heights to a standard coordinated surface. The present investigation has the objective to determine if the arbitrary level assignment represents a serious obstacle to the use of cloud motion wind vectors in the mesoscale analysis of a severe storm environment.

Dust Impact Monitor (SESAME-DIM) on-board Rosetta/Philae: Aerogel as comet analog material

NASA Astrophysics Data System (ADS)

Flandes, Alberto; Albin, Thomas; Arnold, Walter; Fischer, Hans-Herbert; Hirn, Attila; Loose, Alexander; Mewes, Cornelia; Podolak, Morris; Seidensticker, Klaus J.; Volkert, Cynthia; Krüger, Harald

2018-03-01

On 12 November 2014, during the descent of the Rosetta lander Philae to the surface of comet 67P/Churyumov-Gerasimenko the Dust Impact Monitor (DIM) on board Philae recorded an impact of a cometary dust impact of a cometary dust particle at 2.4 km from the comet surface (5 km from the nucleus' barycentre). In this work, we report further experiments that support the identification of this particle. We use aerogel as a comet analog material to characterise the properties of this particle. Our experiments show that this particle has a radius of 0.9 mm, a low density of 0.25 g/cm3 and a high porosity close to 90%. The particle likely moved at near 4 m/s with respect to the comet.

Shock chemistry in SX358 foams

NASA Astrophysics Data System (ADS)

Maerzke, Katie; Coe, Joshua; Fredenburg, Anthony; Lang, John; Dattelbaum, Dana

2017-06-01

We have developed new equation of state models for SX358, a cross-linked PDMS polymer. Recent experiments on SX358 over a range of initial densities (0-65% porous) have yielded new data that allow for a more thorough calibration of the equations of state. SX358 chemically decomposes under shock compression, as evidenced by a cusp in the shock locus. We therefore treat this material using two equations of state, specifically a SESAME model for the unreacted material and a free energy minimization assuming full chemical and thermodynamic equilibrium for the decomposition products. The shock locus of porous SX358 is found to be ``anomalous'' in that the decomposition reaction causes a volume expansion, rather than a volume collapse. Similar behavior has been observed in other polymer foams, notably polyurethane.

PERSEUS QC: preparing statistic data sets

NASA Astrophysics Data System (ADS)

Belokopytov, Vladimir; Khaliulin, Alexey; Ingerov, Andrey; Zhuk, Elena; Gertman, Isaac; Zodiatis, George; Nikolaidis, Marios; Nikolaidis, Andreas; Stylianou, Stavros

2017-09-01

The Desktop Oceanographic Data Processing Module was developed for visual analysis of interdisciplinary cruise measurements. The program provides the possibility of data selection based on different criteria, map plotting, sea horizontal sections, and sea depth vertical profiles. The data selection in the area of interest can be specified according to a set of different physical and chemical parameters complimented by additional parameters, such as the cruise number, ship name, and time period. The visual analysis of a set of vertical profiles in the selected area allows to determine the quality of the data, their location and the time of the in-situ measurements and to exclude any questionable data from the statistical analysis. For each selected set of profiles, the average vertical profile, the minimal and maximal values of the parameter under examination and the root mean square (r.m.s.) are estimated. These estimates are compared with the parameter ranges, set for each sub-region by MEDAR/MEDATLAS-II and SeaDataNet2 projects. In the framework of the PERSEUS project, certain parameters which lacked a range were calculated from scratch, while some of the previously used ranges were re-defined using more comprehensive data sets based on SeaDataNet2, SESAME and PERSEUS projects. In some cases we have used additional sub- regions to redefine the ranges ore precisely. The recalculated ranges are used to improve the PERSEUS Data Quality Control.

Effect of flax addition on the flavor profile and acceptability of bagels.

PubMed

Aliani, Michel; Ryland, Donna; Pierce, Grant N

2012-01-01

Bakery products containing flaxseed, a rich source of alpha linolenic acid (ALA), may provide health benefits. However, the effect of adding flaxseed, especially in the high amounts required for use as the food supplement in clinical trials (23% by weight of the raw ingredients), may affect the flavor characteristics and consumer acceptability. Sensory attributes of bagels containing 30 g of milled flaxseed were evaluated by a 9 member trained panel using a descriptive test and by 89 participants using a consumer test. Grain/flax aroma and flavor were significantly higher for the flax bagels compared to the nonflax bagels. The cinnamon raisin bagel had significantly lower grain/flax aroma and flavor and significantly higher sweet aroma and taste compared to the plain and sunflower sesame types. Older consumers rated the appearance, color, and flavor of the bagels significantly higher than the younger consumers possibly leading to higher compliance in clinical studies for this age group. Bagels with flax showed a significantly lower mean value for flavor acceptability, overall acceptability, and frequency of eating compared to bagels without flax. Appearance, color, and texture acceptability showed no significant differences. The cinnamon raisin bagel had significantly higher flavor acceptance compared to sunflower sesame and plain bagels. In conclusion, for bagels containing 6 g ALA in the form of milled flaxseed, cinnamon raisin appears to be a promising flavoring alternative for ALA fortification for use in clinical trials or as part of the daily diet. Consumers are seeking functional foods that contain omega-3 fatty acids. Bagels made with 23% milled flaxseed (approximately 2 times the amount in regular flax baked products) provided 6 g ALA, an amount high enough to test the efficacy of ALA in human subjects without causing gastrointestinal distress. This study showed that flaxseed aroma and flavor were detected in fortified compared to nonfortified bagels but bagels with this high flaxseed amount were still acceptable with the addition of cinnamon raisin flavoring. Commercial bakeries can use these results to formulate healthy, tasty, and convenient products. © 2011 Institute of Food Technologists®

The effect of sesame and sunflower oils on the plasma disposition of ivermectin in goats.

PubMed

Gokbulut, C; Karademir, U; Boyacioglu, M; McKellar, Q A

2008-10-01

The effect of sesame oil (SSO) and sunflower oil (SFO) (the excipients) on the plasma disposition of ivermectin (IVM) following intravenous (i.v.) and subcutaneous (s.c.) administration at a dosage of 200 microg/kg was investigated in goats. Ten clinically healthy crossbred goats were used in the study. The animals were allocated by weight and sex into two groups of five animals each. Group 1 (n = 5) received the drug and excipient by the i.v. route only and group 2 received drug and excipient by the s.c. route only. The study was designed according to a two-phase crossover design protocol. In the first phase three animals in group 1 were i.v. administered IVM (0.2 mg/kg) + SSO (1 mL) and the other two animals received IVM (0.2 mg/kg) + SFO (1 mL). In the second phase animals were crossed over and received the alternate excipient with IVM at the same dosages. In group 2 during the first phase, three animals were s.c. administered IVM (0.2 mg/kg) + SSO (1 mL) and the other two animals were received IVM (0.2 mg/kg) + SFO (1 mL). In the second phase animals were crossed over and received the alternate excipient with IVM at the same dosages. A 4-week washout period was allowed between the two phases. In group 2 significantly increased dermal thickness was observed at the s.c. injection site of the all animals which received IVM during phase I regardless of the excipient. There was almost no change observed at the injection site of any animal during the second phase of the study following s.c. administration. In group 2 the plasma concentrations of IVM in the second phase for both excipient combinations were much higher than the plasma concentrations following first administration and appeared to be related with the dermal changes. The mean plasma disposition of IVM in combination with SSO or SFO was similar following i.v. administration. Longer terminal elimination half-lives and resultant longer mean resident time were observed after s.c. administration of the both combinations compared with i.v. administration.

Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants.

PubMed

Perkin, Michael R; Logan, Kirsty; Tseng, Anna; Raji, Bunmi; Ayis, Salma; Peacock, Janet; Brough, Helen; Marrs, Tom; Radulovic, Suzana; Craven, Joanna; Flohr, Carsten; Lack, Gideon

2016-05-05

The age at which allergenic foods should be introduced into the diet of breast-fed infants is uncertain. We evaluated whether the early introduction of allergenic foods in the diet of breast-fed infants would protect against the development of food allergy. We recruited, from the general population, 1303 exclusively breast-fed infants who were 3 months of age and randomly assigned them to the early introduction of six allergenic foods (peanut, cooked egg, cow's milk, sesame, whitefish, and wheat; early-introduction group) or to the current practice recommended in the United Kingdom of exclusive breast-feeding to approximately 6 months of age (standard-introduction group). The primary outcome was food allergy to one or more of the six foods between 1 year and 3 years of age. In the intention-to-treat analysis, food allergy to one or more of the six intervention foods developed in 7.1% of the participants in the standard-introduction group (42 of 595 participants) and in 5.6% of those in the early-introduction group (32 of 567) (P=0.32). In the per-protocol analysis, the prevalence of any food allergy was significantly lower in the early-introduction group than in the standard-introduction group (2.4% vs. 7.3%, P=0.01), as was the prevalence of peanut allergy (0% vs. 2.5%, P=0.003) and egg allergy (1.4% vs. 5.5%, P=0.009); there were no significant effects with respect to milk, sesame, fish, or wheat. The consumption of 2 g per week of peanut or egg-white protein was associated with a significantly lower prevalence of these respective allergies than was less consumption. The early introduction of all six foods was not easily achieved but was safe. The trial did not show the efficacy of early introduction of allergenic foods in an intention-to-treat analysis. Further analysis raised the question of whether the prevention of food allergy by means of early introduction of multiple allergenic foods was dose-dependent. (Funded by the Food Standards Agency and others; EAT Current Controlled Trials number, ISRCTN14254740.).

Transcranial route of brain targeted delivery of methadone in oil.

PubMed

Pathirana, W; Abhayawardhana, P; Kariyawasam, H; Ratnasooriya, W D

2009-05-01

The unique anatomical arrangement of blood vessels and sinuses in the human skull and the brain, the prevalence of a high density of skin appendages in the scalp, extracranial vessels of the scalp communicating with the brain via emissary veins and most importantly, the way that the scalp is used in Ayurvedic medical system in treating diseases associated with the brain show that a drug could be transcranially delivered and targeted to the brain through the scalp. The present study was to investigate by measuring the antinociceptive effect on rats whether the opioid analgesic methadone could be delivered and targeted to the brain by transcranial delivery route. A non aqueous solution of methadone base in sesame oil was used for the application on the scalp. Animal studies were carried out using six groups of male rats consisting of group 1, the oral control treated with distilled water 1 ml; group 2, the oral positive control treated with methadone hydrochloride solution 316.5 mug/ml; group 3, the negative control treated transcranially with the blank sesame oil 0.2 ml and three test groups 4, 5 and 6 treated with three different dose levels of the transcranial oil formulation of methadone base, 41.6 mug/0.2 ml, 104 mug/0.2 ml and 208 mug/0.2 ml, respectively. The antinociceptive effects were examined by subjecting the rats to the hot plate and tail flick tests. The two higher concentrations of the three transcranial methadone formulations yielded response vs time curves showing nearly equal maximum antinociceptive effects similar to that of the oral positive control. Maximum analgesic effect after transcranial administration was observed between 1st and 2nd h and declined up to 6th hour. The results indicate that the transcranial brain targeted delivery of methadone base in the form of an oil based non aqueous solution results in statistically significant antinociceptive effects under experimental conditions. Therefore, it is possible to deliver central nervous system drugs through the proposed transcranial route when suitably formulated.

Effect of feeding complete feed block containing rumen protected protein, non-protein nitrogen and rumen protected fat on improving body condition and carcass traits of cull ewes.

PubMed

Bhatt, R S; Sahoo, A

2017-12-01

Nutrient utilization, body condition and carcass traits of cull ewes were studied in three dietary regimens based on complete feed block (CFB) feeding to control (C) with rumen protected protein (RPP), CU [RPP + urea (6 g/kg)] and CUF [RPP + urea + rumen protected fat (RPF; 40 g/kg)]. The RPP component (g/kg) in C had 1% formaldehyde-treated soy flakes 50, mustard cake 50 and sesame cake 30. The mustard and sesame cakes were replaced with urea on equivalent N basis in CU and CUF. The ewes were offered ad libitum CFB composed (g/kg) of concentrate 650, roughage 300 and molasses 50. The digestibility of OM and EE was higher (p < 0.05) in CUF than in CU and C, while that of NDF and ADF was lower (p < 0.05). The CP digestibility was higher in both CU and CUF. Utilization of N and Ca was higher (p < 0.05) in CUF compared with C and CU. Urinary purine derivatives analysis and microbial N synthesis were similar in all the groups. Blood glucose concentration improved at 90 day compared with 0 day. Ruminal attributes showed a higher (p < 0.05) pH, total N, TCA precipitable N, entodiniomorphs and total ciliate population in CU and CUF than in the control. The CUF had higher (p < 0.01) DM, digestible OM and ME intake, which resulted in higher (p < 0.05) weight gain and better feed efficiency. Ewes in all the groups showed an improvement in carcass traits at 90 day. The pre-slaughter weight was higher (p < 0.05) and dissected and KOH bone content was lower in CUF. Thus, feeding of CFB with urea as a cheaper N source and RPF to enrich with energy supported the improved performance as evidenced from higher nutrient input, 'utilization and efficiency with enhanced carcass traits' for better marketability and returns from cull ewes. Journal of Animal Physiology and Animal Nutrition © 2017 Blackwell Verlag GmbH.

Effect of Citrullus colocynthis hydro-alcoholic extract on hormonal and folliculogenesis process in estradiol valerate-induced PCOs rats model: An experimental study.

PubMed

Barzegar, Mohammad Hossein; Khazali, Homayoun; Kalantar, Seyyed Mehdi; Khoradmehr, Arezoo

2017-10-01

Citrullus colocynthis (CCT) is used as the anti-diabetic and antioxidant agent. Polycystic ovarian syndrome (PCOS) is a reproductive disorder which level of gonadotropins and sexual hormones are imbalanced. We evaluated the effect of CCT hydro-alcoholic extract on hormonal and folliculogenesis process in estradiol valerate-induced PCOs rats' model. 40 female adult Wistar rats divided into five groups (n=8each: Group I (control) only injected by sesame oil as estradiol valerate solvent, group II (Sham) was orally received normal saline after estradiol valerate- induced polycystic ovarian syndrome (4 mg/rat estradiol valerate, intramuscularly), and three experimental groups, that after induction of PCOS within 60 days, received orally 50 mg/kg CCT extract (group III), 50mg/kg metformin (group IV), and CCT extract+ metformin (group V) for 20 days. The serum concentration level of luteinizing, testosterone and follicle stimulating hormones were measured using ELISA method and the serum concentration level of glucose were measured using the oxidative method (glucose meter). Histological study of ovary tissue carried out by hematoxylin-eosin staining. There was a significant reduction in luteinizing hormone and testosterone in III-V groups compared to Sham group, whereas follicle stimulating hormone in III-V groups was not significantly changed in comparison with Sham group. Histological investigations showed a significant increase in number of preantral and antral follicles and corpus luteum in the experimental groups compared to group II. Marked improvement in hormonal and histological symptoms of PCOS may be due to CCT effects hence, CCT can potentially be considered as an effective drug for treatment of PCOS.

Effect of Citrullus colocynthis hydro-alcoholic extract on hormonal and folliculogenesis process in estradiol valerate-induced PCOs rats model: An experimental study

PubMed Central

Barzegar, Mohammad Hossein; Khazali, Homayoun; Kalantar, Seyyed Mehdi; Khoradmehr, Arezoo

2017-01-01

Background: Citrullus colocynthis (CCT) is used as the anti-diabetic and antioxidant agent. Polycystic ovarian syndrome (PCOS) is a reproductive disorder which level of gonadotropins and sexual hormones are imbalanced. Objective: We evaluated the effect of CCT hydro-alcoholic extract on hormonal and folliculogenesis process in estradiol valerate-induced PCOs rats’ model. Materials and Methods: 40 female adult Wistar rats divided into five groups (n=8each: Group I (control) only injected by sesame oil as estradiol valerate solvent, group II (Sham) was orally received normal saline after estradiol valerate- induced polycystic ovarian syndrome (4 mg/rat estradiol valerate, intramuscularly), and three experimental groups, that after induction of PCOS within 60 days, received orally 50 mg/kg CCT extract (group III), 50mg/kg metformin (group IV), and CCT extract+ metformin (group V) for 20 days. The serum concentration level of luteinizing, testosterone and follicle stimulating hormones were measured using ELISA method and the serum concentration level of glucose were measured using the oxidative method (glucose meter). Histological study of ovary tissue carried out by hematoxylin-eosin staining. Results: There was a significant reduction in luteinizing hormone and testosterone in III-V groups compared to Sham group, whereas follicle stimulating hormone in III-V groups was not significantly changed in comparison with Sham group. Histological investigations showed a significant increase in number of preantral and antral follicles and corpus luteum in the experimental groups compared to group II. Conclusion: Marked improvement in hormonal and histological symptoms of PCOS may be due to CCT effects hence, CCT can potentially be considered as an effective drug for treatment of PCOS. PMID:29387832

Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils

PubMed Central

Lin, Tzu-Kai; Zhong, Lily; Santiago, Juan Luis

2017-01-01

Plant oils have been utilized for a variety of purposes throughout history, with their integration into foods, cosmetics, and pharmaceutical products. They are now being increasingly recognized for their effects on both skin diseases and the restoration of cutaneous homeostasis. This article briefly reviews the available data on biological influences of topical skin applications of some plant oils (olive oil, olive pomace oil, sunflower seed oil, coconut oil, safflower seed oil, argan oil, soybean oil, peanut oil, sesame oil, avocado oil, borage oil, jojoba oil, oat oil, pomegranate seed oil, almond oil, bitter apricot oil, rose hip oil, German chamomile oil, and shea butter). Thus, it focuses on the therapeutic benefits of these plant oils according to their anti-inflammatory and antioxidant effects on the skin, promotion of wound healing and repair of skin barrier. PMID:29280987

Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils.

PubMed

Lin, Tzu-Kai; Zhong, Lily; Santiago, Juan Luis

2017-12-27

Plant oils have been utilized for a variety of purposes throughout history, with their integration into foods, cosmetics, and pharmaceutical products. They are now being increasingly recognized for their effects on both skin diseases and the restoration of cutaneous homeostasis. This article briefly reviews the available data on biological influences of topical skin applications of some plant oils (olive oil, olive pomace oil, sunflower seed oil, coconut oil, safflower seed oil, argan oil, soybean oil, peanut oil, sesame oil, avocado oil, borage oil, jojoba oil, oat oil, pomegranate seed oil, almond oil, bitter apricot oil, rose hip oil, German chamomile oil, and shea butter). Thus, it focuses on the therapeutic benefits of these plant oils according to their anti-inflammatory and antioxidant effects on the skin, promotion of wound healing and repair of skin barrier.

Ultra-flat and ultra-broadband supercontinuum generation in photonic crystal fiber pumped by noise-like pulses

NASA Astrophysics Data System (ADS)

Chen, Yewang; Ruan, Shuangchen; Wu, Xu; Guo, Chunyu; Liu, Weiqi; Yu, Jun; Luo, Ruoheng; Ren, Xikui; Zhu, Yihuai

2017-02-01

An ultra-flat and ultra-broadband supercontinuum (SC) is demonstrated in a 4-m photonic crystal fiber (PCF) pumped by an Yb-doped all-fiber noise-like pulses (NLP) laser. The Yb-doped fiber laser is seeded by a SESAM mode-locked fiber laser, and amplified by cascaded fiber amplifiers, with its center wavelength, repetition frequency and the average noise-like bunch duration of 1064.52 nm, 50.18 MHz, 9.14 ps, respectively. Pumped by this NLP laser, the SC source has a 3 dB bandwidth and a 7 dB bandwidth (ignore the pump residue) of 1440 nm and 1790 nm at the maximum average output power of 6.94 W. To the best of our knowledge, this flatness is significantly prominent for the performance of PCF-based SC sources.

Organizational effects of diethylstilbestrol on brain vasotocin and sexual behavior in male quail.

PubMed

Viglietti-Panzica, Carla; Montoncello, Barbara; Mura, Elena; Pessatti, Marzia; Panzica, GianCarlo

2005-04-15

In Japanese quail, we previously described a sexual dimorphism of the parvocellular vasotocin system of the limbic region that, as the reproductive behavior, is steroid-sensitive and is organized during embryonic life by the exposure to estradiol. We verified in this study whether diethylstilbestrol, a chemical xenoestrogen, has analogous organizational effects on the vasotocin system of limbic regions and on copulatory behavior of male Japanese quail. We injected in the yolk sac of 3 day-old quail embryos diethylstilbestrol or estradiol benzoate (a treatment which suppresses male copulatory behavior in adulthood and reduces vasotocin innervation), or sesame oil (control). No further hormonal manipulations were performed after hatching. Sexual behavior was recorded in males at the age of 6 weeks. Estradiol- and diethylstilbestrol-treated males exhibited a total suppression of copulatory behavior. After behavioral tests, all males were sacrificed and brain sections processed for vasotocin immunocytochemistry. Significant decrease in the density of vasotocin immunoreactivity was detected in the medial preoptic nucleus, in the bed nucleus of stria terminalis, and in the lateral septum of diethylstilbestrol-treated males. The magnocellular vasotocin neurons were, in contrast, not affected. In conclusion, the present data demonstrate that embryonic treatment with diethylstilbestrol induces a full sex reversal of behavioral phenotype as well as a significant decrease of vasotocin expression in the preoptic-limbic region in male Japanese quail. Therefore, the parvocellular vasotocin system could represent an optimal model to investigate the effects of pollutants on neural circuits controlling reproductive functions.

Rapid liquid chromatography-tandem mass spectrometry analysis of 4-hydroxynonenal for the assessment of oxidative degradation and safety of vegetable oils.

PubMed

Gabbanini, Simone; Matera, Riccardo; Valvassori, Alice; Valgimigli, Luca

2015-04-15

A novel method for the UHPLC-MS/MS analysis of (E)-4-hydroxynonenal (4-HNE) is described. The method is based on derivatization of 4-HNE with pentafluorophenylhydrazine (1) or 4-trifluoromethylphenylhydrazine (2) in acetonitrile in the presence of trifluoroacetic acid as catalyst at room temperature and allows complete analysis of one sample of vegetable oil in only 21 min, including sample preparation and chromatography. The method involving hydrazine 1, implemented in an ion trap instrument with analysis of the transition m/z 337→154 showed LOD=10.9 nM, average accuracy of 101% and precision ranging 2.5-4.0% RSD intra-day (2.7-4.1% RSD inter-day), with 4-HNE standard solutions. Average recovery from lipid matrices was 96.3% from vaseline oil, 91.3% from sweet almond oil and 105.3% from olive oil. The method was tested on the assessment of safety and oxidative degradation of seven samples of dietary oil (soybean, mixed seeds, corn, peanut, sunflower, olive) and six cosmetic-grade oils (avocado, blackcurrant, apricot kernel, echium, sesame, wheat germ) and effectively detected increased 4-HNE levels in response to chemical (Fenton reaction), photochemical, or thermal stress and aging, aimed at mimicking typical oxidation associated with storage or industrial processing. The method is a convenient, cost-effective and reliable tool to assess quality and safety of vegetable oils. Copyright © 2015 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Shuai; Driver, Kevin P.; Soubiran, Francois

As one of the simple alkali metals, sodium has been of fundamental interest for shock physics experiments, but knowledge of its equation of state (EOS) in hot, dense regimes is not well known. By combining path integral Monte Carlo (PIMC) results for partially ionized states at high temperatures and density functional theory molecular dynamics (DFT-MD) results at lower temperatures, we have constructed a coherent equation of state for sodium over a wide density-temperature range of 1.93-11.60 g/cm 3 and 10 3–1.29×10 8 K. We find that a localized, Hartree-Fock nodal structure in PIMC yields pressures and internal energies that aremore » consistent with DFT-MD at intermediate temperatures of 2×10 6 K. Since PIMC and DFT-MD provide a first-principles treatment of electron shell and excitation effects, we are able to identify two compression maxima in the shock Hugoniot curve corresponding to K-shell and L-shell ionization. Our Hugoniot curves provide a benchmark for widely used EOS models: SESAME, LEOS, and Purgatorio. Due to the low ambient density, sodium has an unusually high first compression maximum along the shock Hugoniot curve. At beyond 10 7 K, we show that the radiation effect leads to very high compression along the Hugoniot curve, surpassing relativistic corrections, and observe an increasing deviation of the shock and particle velocities from a linear relation. Here, we also compute the temperature-density dependence of thermal and pressure ionization processes.« less

Determination of acrylamide in processed foods by LC/MS using column switching.

PubMed

Takatsuki, Satoshi; Nemoto, Satoru; Sasaki, Kumiko; Maitani, Tamio

2003-04-01

An LC/MS method was developed for the determination of acrylamide (AA) in processed or cooked foods. AA was extracted with a mixture of water and acetone from homogenized food samples after the addition of 13C-labeled acrylamide (AA-1-(13)C) as an internal standard. The extract was concentrated, washed with dichloromethane for defatting, and cleaned up on Bond Elut C18, PSA and ACCUCAT cartridge-columns, and then AA was determined by LC/MS in the selected ion recording (SIR) mode. For the LC/MS analysis, four LC columns were connected in-line and the flow of the mobile phase was switched according to a time-program. Monitoring ions for AA were m/z 72 and 55, and those for AA-1-(13)C were m/z 73 and 56. AA and AA-1-(13)C were determined without interference from the matrices in all samples. The recoveries of AA from potato chips, corn snack, pretzel and roasted tea spiked at the level of 500 ng/g of AA were 99.5-101.0% with standard deviations (SD) in the range from 0.3 to 1.6%. The limits of detection and quantification of the developed method were 9 and 30 ng/g for AA in samples, respectively. The method was applied to the analysis of AA in various processed or cooked food samples purchased from retail markets. High levels of AA were found in potato chips and French-fried potato (467-3,544 ng/g). Fried and sugar-coated dough cakes (karinto) contained 374 and 1,895 ng/g. Corn snacks contained 117-535 ng/g of AA. Roasted foods (such as roasted sesame seed, roasted barley (mugi-cha), roasted tea (hoji-cha), coffee beans and curry powder) contained 116-567 ng/g of AA. Foods made from fish, egg and meat contained lower levels of AA than the plant-based foods. Foods containing much water showed a tendency to have low levels of AA compared with dry foods. The proposed method was applicable to the analysis of AA in variety of processed foods.

HemoHIM improves ovarian morphology and decreases expression of nerve growth factor in rats with steroid-induced polycystic ovaries.

PubMed

Kim, Sung Ho; Lee, Hae June; Kim, Joong Sun; Moon, Changjong; Kim, Jong Choon; Bae, Chun Sik; Park, Hae Ran; Jung, Uhee; Jo, Sung Kee

2009-12-01

Estradiol valerate (EV)-induced polycystic ovaries (PCOs) in rats cause the anovulation and cystic ovarian morphology. We investigated whether treatment with HemoHIM influences the ovarian morphology and the expression of nerve growth factor (NGF) in an EV-induced PCO rat model. PCO was induced by a single intramuscular injection of EV (4 mg, dissolved in sesame oil) in adult cycling rats. HemoHIM was either administered orally (100 mg/kg of body weight/day) for 35 consecutive days or injected intraperitoneally (50 mg/kg of body weight) every other day after EV injection. Ovarian morphology was almost normalized, and NGF was normalized in the PCO + HemoHIM group. HemoHIM lowered the high numbers of antral follicles and increased the number of corpora lutea in PCOs. The results are consistent with a beneficial effect of HemoHIM in the prevention and treatment of PCO syndrome.

Isolation and characterization of diazotrophic growth promoting bacteria from rhizosphere of agricultural crops of Korea.

PubMed

Park, Myoungsu; Kim, Chungwoo; Yang, Jinchul; Lee, Hyoungseok; Shin, Wansik; Kim, Seunghwan; Sa, Tongmin

2005-01-01

Free-living nitrogen fixing bacteria were isolated from rhizosphere of seven different plant namely sesame, maize, wheat, soybean, lettuce, pepper and rice grown in Chungbuk Province, Korea. Five isolates with nitrogenase activity above 150nmol(-1) mg(-1) protein were identified based on, phenotypic and 16S rDNA sequences analysis. The strains were identified as Stenotrophomonas maltophilia (PM-1, PM-26), Bacillus fusiformis (PM-5, PM-24) and Pseudomonas fluorescens (PM-13), respectively. All the isolates produced indole-3-acetic acid (IAA), in the presence of tryptophan, ranging from 100.4 microg ml(-1) (PM-13) to 255 microg ml(-1) (PM-24). The isolate PM-24 (Bacillus fusiformis) exhibiting highest nitrogenase activity (3677.81 nmol h(-1) mg(-1) protein) and IAA production (255microg ml(-1)) has a promising potential for developing as a plant growth promoting rhizobacteria.

Synchrotron light sources in developing countries

DOE PAGES

Mtingwa, Sekazi K.; Winick, Herman

2018-03-21

Here, we discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure andmore » Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.« less

Analytic EoS and PTW strength model recommendation for Starck Ta

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjue, Sky K.; Prime, Michael B.

2016-09-01

The purpose of this document is to provide an analytic EoS and PTW strength model for Starck Ta that can be consistently used between different platforms and simulations at three labs. This should provide a consistent basis for comparison of the results of calculations, but not the best implementation for matching a wide variety of experimental data. Another version using SESAME tables should follow, which will provide a better physical representation over a broader range of conditions. The data sets available at the time only include one Hopkinson bar at a strain rate of 1800/s; a broader range of high-ratemore » calibration data would be preferred. The resulting fit gives the PTW parameter p = 0. To avoid numerical issues, p = 0:001 has been used in FLAG. The PTW parameters that apply above the maximum strain rate in the data use the values from the original publication.« less

Synchrotron light sources in developing countries

NASA Astrophysics Data System (ADS)

Mtingwa, Sekazi K.; Winick, Herman

2018-03-01

We discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure and Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.

A subsynoptic-scale kinetic energy study of the Red River Valley tornado outbreak (AVE-SESAME 1)

NASA Technical Reports Server (NTRS)

Jedlovec, G. J.; Fuelberg, H. E.

1981-01-01

The subsynoptis-scale kinetic energy balance during the Red River Valley tornado outbreak is presented in order to diagnose storm environment interactions. Area-time averaged energetics indicate that horizontal flux convergence provides the major energy source to the region, while cross contour flow provides the greatest sink. Maximum energy variability is found in the upper levels in association with jet stream activity. Area averaged energetics at individual observation times show that the energy balance near times of maximum storm activity differs considerably from that of the remaining periods. The local kinetic energy balance over Oklahoma during the formation of a limited jet streak receives special attention. Cross contour production of energy is the dominant local source for jet development. Intense convection producing the Red River Valley tornadoes may have contributed to this local development by modifying the surrounding environment.

Initialization of a mesoscale model for April 10, 1979, using alternative data sources

NASA Technical Reports Server (NTRS)

Kalb, M. W.

1984-01-01

A 35 km grid limited area mesoscale model was initialized with high density SESAME radiosonde data and high density TIROS-N satellite temperature profiles for April 10, 1979. These data sources were used individually and with low level wind fields constructed from surface wind observations. The primary objective was to examine the use of satellite temperature data for initializing a mesoscale model by comparing the forecast results with similar experiments employing radiosonde data. The impact of observed low level winds on the model forecasts was also investigated with experiments varying the method of insertion. All forecasts were compared with each other and with mesoscale observations for precipitation, mass and wind structure. Several forecasts produced convective precipitation systems with characteristics satisfying criteria for a mesoscale convective complex. High density satellite temperature data and balanced winds can be used in a mesoscale model to produce forecasts which verify favorably with observations.

Cellulose Anionic Hydrogels Based on Cellulose Nanofibers As Natural Stimulants for Seed Germination and Seedling Growth.

PubMed

Zhang, Hao; Yang, Minmin; Luan, Qian; Tang, Hu; Huang, Fenghong; Xiang, Xia; Yang, Chen; Bao, Yuping

2017-05-17

Cellulose anionic hydrogels were successfully prepared by dissolving TEMPO-oxidized cellulose nanofibers in NaOH/urea aqueous solution and being cross-linked with epichlorohydrin. The hydrogels exhibited microporous structure and high hydrophilicity, which contribute to the excellent water absorption property. The growth indexes, including the germination rate, root length, shoot length, fresh weight, and dry weight of the seedlings, were investigated. The results showed that cellulose anionic hydrogels with suitable carboxylate contents as plant growth regulators could be beneficial for seed germination and growth. Moreover, they presented preferable antifungal activity during the breeding and growth of the sesame seed breeding. Thus, the cellulose anionic hydrogels with suitable carboxylate contents could be applied as soilless culture mediums for plant growth. This research provided a simple and effective method for the fabrication of cellulose anionic hydrogel and evaluated its application in agriculture.

Direct emission of chirality controllable femtosecond LG01 vortex beam

NASA Astrophysics Data System (ADS)

Wang, S.; Zhang, S.; Yang, H.; Xie, J.; Jiang, S.; Feng, G.; Zhou, S.

2018-05-01

Direct emission of a chirality controllable ultrafast LG01 mode vortex optical beam from a conventional z-type cavity design SESAM (SEmiconductor Saturable Absorber Mirror) mode locked LD pumped Yb:Phosphate laser has been demonstrated. A clean 360 fs vortex beam of ˜45.7 mW output power has been achieved. A radial shear interferometer has been built to determine the phase singularity and the wavefront helicity of the ultrafast output laser. Theoretically, it is found that the LG01 vortex beam is obtained via the combination effect of diagonal HG10 mode generation by off-axis pumping and the controllable Gouy phase difference between HG10 and HG01 modes in the sagittal and tangential planes. The chirality of the LG01 mode can be manipulated by the pump position to the original point of the laser cavity optical axis.

The ePLAS code for Ignition Studies

NASA Astrophysics Data System (ADS)

Faehl, R. J.; Mason, R. J.; Kirkpatrick, R. C.

2012-10-01

The ePLAS code is a multi-fluid/PIC hybrid developing self-consistent E & B-fields by the Implicit Moment Method for stable calculations of high density plasma problems with voids on the electron Courant time scale. See: http://www.researchapplicationscorp.com. Here, we outline typical applications to: 1) short pulse driven electron transport along void (or high Z) insulated wires, and 2) the 2D development of shock ignition pressure peaks with B-fields. We outline the code's recent inclusion of SESAME EOS data, a DT/DD burn capability, a new option for K-alpha imaging of modeling output, and demonstrate a foil expansion tracked with either fluid or particle ions. Also, we describe a new super-hybrid extension of our implicit solver that permits full target dynamics studies on the ion Courant scale. Finally, we will touch on the very recent application of ePLAS to possible non-local/kinetic hydro effects NIF capsules.

Luminescent and lasing characteristics of heavily doped Yb{sup 3+}:KY(WO{sub 4}){sub 2} crystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kisel', V E; Troshin, A E; Shcherbitskii, V G

The luminescence decay times are measured taking into account reabsorption for KY(WO{sub 4}){sub 2}:Yb(KYW:Yb) crystals with atomic concentrations of active ions from 0.2% to 30%. The radiative lifetime of Yb{sup 3+} ions was measured to be 233 {mu}s. The cw output power of 1.46 and 1.62 W was achieved with the slope efficiency 52% and 47% for Yb:KYW lasers with the atomic concentration of Yb{sup 3+} ions equal to 10% and 30%, respectively. Using a semiconductor mirror with a saturable absorber (SESAM) in the passive mode-locking regime, pulses of duration 194 and 180 fs were obtained at wavelengths of 1042more » and 1039 nm for crystals with Yb{sup 3+} concentrations equal to 10% and 30%, respectively, the average output power being 0.63 and 0.75 W. (lasers and amplifiers)« less

Synchrotron light sources in developing countries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mtingwa, Sekazi K.; Winick, Herman

Here, we discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure andmore » Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.« less

SESAME-A System of Equations for the Simulation of Aircraft in a Modular Environment.

DTIC Science & Technology

1979-01-01

LCU lAT E 5007 1115 4(t.8C17155 259 CALL SV (LOCI 264/ C C ALCULATE ALPHA * 1 *0 5E7A *510 ASSOCIAT ED E15.L5,C051N18 3* 1 C ALL SAL ’B( TlO 1L!Il 252 15*0...SIIANYI,, 11 .CRIP,IIP. UNITS CALC U LAT (S) U$ID RI. RANG IN IN • • 1 N’ ISTAL sIR ~P5%9 P I.’55 c 1 ~ 115( 1 liNt? IPELICS 45 VII? II?*~ AI R •PIED ..NFYI...79008~J â V L IJ lIJ~~00 0 10 ~) 0 1 ” “ROYAL AIRCRAFT ESTABLISHMENT * c 1 ’~~ech n Ic a I ~~t~~9 0 63i ~~ SAME—A SYSTEM OF EQUATIONSI OF AIRCRAFTL_

Formulation of a drinkable peanut-based therapeutic food for malnourished children using plant sources.

PubMed

Nabuuma, Deborah; Nakimbugwe, Dorothy; Byaruhanga, Yusuf B; Saalia, Firibu Kwesi; Phillips, Robert Dixon; Chen, Jinru

2013-06-01

High ingredient costs continue to hamper local production of therapeutic foods (TFs). Development of formulations without milk, the most expensive ingredient, is one way of reducing cost. This study formulated a ready-to-drink peanut-based TF that matched the nutrient composition of F100 using plant sources. Three least cost formulations namely, A, B and C were designed using computer formulation software with peanuts, beans, sesame, cowpeas and grain amaranth as ingredients. A 100 g portion of the TF provided 101-111 kcal, 5 g protein and 5.3-6.5 g fat. Consumer acceptability hedonic tests showed that the products were liked (extremely and moderately) by 62-65% of mothers. These results suggest that nutrient dense TFs formulated from only plant sources have the potential to be used in the rehabilitation phase of the management of malnourished children after clinical testing.

A Comprehensive Review on Rasam: A South Indian Traditional Functional Food.

PubMed

Devarajan, Agilandeswari; Mohanmarugaraja, M K

2017-01-01

The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam , a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water. Rasam is a classic example of traditional functional food with all its ingredients medicinally claimed for various ailments. The preclinical and clinical studies on rasam and its ingredients support their traditional claim. This review is an attempt to compile the literatures on rasam , its ingredients, and to highlight its medicinal potential that has been underestimated.

Uniform heating of materials into the warm dense matter regime with laser-driven quasimonoenergetic ion beams

DOE PAGES

Bang, W.; Albright, B. J.; Bradley, P. A.; ...

2015-12-01

In a recent experiment at the Trident laser facility, a laser-driven beam of quasimonoenergetic aluminum ions was used to heat solid gold and diamond foils isochorically to 5.5 and 1.7 eV, respectively. Here theoretical calculations are presented that suggest the gold and diamond were heated uniformly by these laser-driven ion beams. According to calculations and SESAME equation-of-state tables, laser-driven aluminum ion beams achievable at Trident, with a finite energy spread of ΔE/E~20%, are expected to heat the targets more uniformly than a beam of 140-MeV aluminum ions with zero energy spread. As a result, the robustness of the expected heatingmore » uniformity relative to the changes in the incident ion energy spectra is evaluated, and expected plasma temperatures of various target materials achievable with the current experimental platform are presented.« less

A kinetic energy analysis of the meso beta-scale severe storm environment

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Printy, M. F.

1984-01-01

Analyses are performed of the meso beta-scale (20-200 km wavelengths and several hours to one-day periods) severe storm kinetic energy balance on the fifth day of the AVE SESAME campaign of May 1979. A 24-hr interval covering the antecedent, active and post-convective outbreak activity over Oklahoma are considered. Use is made of the kinetic energy budget equation (KEBE) for a finite volume in an isobaric coordinate system. Rawindsonde data with 75 km resolution were treated. The KEBE model covered changes in kinetic energy due to the cross contour flows, horizontal and vertical components of flux divergence, and volumic mass changes on synoptic and subsynoptic scales. The greatest variability was concentrated above 400 mb height and over the most intense storm activity. Energy was generated at the highest rates in divergence and decreased the most in convection. The meso beta-scale lacked sufficient resolution for analyzing mesoscale activity.

Shock and Release Response of Unreacted Epon 828: Shot 2s-905

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pisa, Matthew Alexander; Fredenburg, David A.; Dattelbaum, Dana M.

This document summarizes the shock and release response of Epon 828 measured in the dynamic impact experiment 2s-905. Experimentally, a thin Kel-F impactor backed by a low impedance foam impacted an Epon 828 target with embedded electromagnetic gauges. Computationally, a one dimensional simulation of the impact event was performed, and tracer particles were located at the corresponding electromagnetic gauge locations. The experimental configuration was such that the Epon 828 target was initially shocked, and then allowed to release from the high-pressure state. Comparisons of the experimental gauge and computational tracer data were made to assess the performance of equation ofmore » state (EOS) 7603, a SESAME EOS for Epon 828, on and off the principal shock Hugoniot. Results indicate that while EOS 7603 can capture the Hugoniot response to better that 1%, while the sound speeds at pressure are under-predicted by 6 - 7%.« less

A Comprehensive Review on Rasam: A South Indian Traditional Functional Food

PubMed Central

Devarajan, Agilandeswari; Mohanmarugaraja, M. K.

2017-01-01

The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam, a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water. Rasam is a classic example of traditional functional food with all its ingredients medicinally claimed for various ailments. The preclinical and clinical studies on rasam and its ingredients support their traditional claim. This review is an attempt to compile the literatures on rasam, its ingredients, and to highlight its medicinal potential that has been underestimated. PMID:28989243

Watt-level passively Q-switched heavily Er3+-doped ZBLAN fiber laser with a semiconductor saturable absorber mirror

PubMed Central

Shen, Yanlong; Wang, Yishan; Luan, Kunpeng; Huang, Ke; Tao, Mengmeng; Chen, Hongwei; Yi, Aiping; Feng, Guobin; Si, Jinhai

2016-01-01

A diode-cladding pumped mid-infrared passively Q-switched Er3+-doped ZBLAN fiber laser with an average output power of watt-level based on a semiconductor saturable absorber mirror (SESAM) is demonstrated. Stable pulse train was produced at a slope efficiency of 17.8% with respect to launched pump power. The maximum average power of 1.01 W at a repetition rate of 146.3 kHz was achieved with a corresponding pulse energy of 6.9 μJ, from which the maximum peak power was calculated to be 21.9 W. To the best of our knowledge, the average power and the peak power are the highest in 3 μm region passively Q-switched fiber lasers. The influence of gain fiber length on the operation regime of the fiber laser has been investigated in detail. PMID:27225029

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romaen, R.

A protein fraction capable of inhibit in vitro protein synthesis was found in potato tubers in fresh and wounded tissue. Inhibitor activity from fresh tissue decays with wounding. Inhibition activity was detected absorbed to ribsomal fraction and cytosol of potato tuber tissue by a partially reconstituted in vitro system from potato tuber and wheat germ. Adsorbed ribosomal fraction was more suitable of purification. This fraction was washed from ribosomes with 0.3M KCl, concentrated with ammonium sulfate precipitation and purified through sephadex G100 and sephadex G-75 columns chromatography. After 61 fold purification adsorbed protein fraction can inhibit germination of maize, wheatmore » and sesame seeds, as well as {sup 3}H-leucine incorporation into protein by imbibed maize embryos. Inhibition activity was lost by temperature, alkali and protease-K hydrolysis. Preliminar analysis could not show presence of reductor sugars. Physiological role of this inhibitor in relation to rest and active tissue remains to be studied.« less

Uniform heating of materials into the warm dense matter regime with laser-driven quasimonoenergetic ion beams

NASA Astrophysics Data System (ADS)

Bang, W.; Albright, B. J.; Bradley, P. A.; Vold, E. L.; Boettger, J. C.; Fernández, J. C.

2015-12-01

In a recent experiment at the Trident laser facility, a laser-driven beam of quasimonoenergetic aluminum ions was used to heat solid gold and diamond foils isochorically to 5.5 and 1.7 eV, respectively. Here theoretical calculations are presented that suggest the gold and diamond were heated uniformly by these laser-driven ion beams. According to calculations and SESAME equation-of-state tables, laser-driven aluminum ion beams achievable at Trident, with a finite energy spread of ΔE /E ˜20 %, are expected to heat the targets more uniformly than a beam of 140-MeV aluminum ions with zero energy spread. The robustness of the expected heating uniformity relative to the changes in the incident ion energy spectra is evaluated, and expected plasma temperatures of various target materials achievable with the current experimental platform are presented.

[Effects of bisphenol A on the placental function and reproduction in rats].

PubMed

Lee, Chae-Kwan; Kim, Seog-Hyun; Moon, Deog-Hwan; Kim, Jeong-Ho; Son, Byung-Chul; Kim, Dae-Hwan; Lee, Chang-Hee; Kim, Hwi-Dong; Kim, Jung-Won; Kim, Jong-Eun; Lee, Chae-Un

2005-08-01

The aim of this study was to investigate the effects of bisphenol A (BPA), an estrogen-like environmental endocrine disrupter, on the placental function and reproduction in rats. The mRNA levels of the placental prolactin-growth hormone(PRL-GH) gene family, placental trophoblast cell frequency and reproductive data were analyzed. The pregnancies of F344 Fisher rats (160 g +/-20 g) were detected by the presence of the copulatory plug or sperm in the vaginal smear, which marked Day 0 of pregnancy. Pregnant rats were divided into three groups. The control group was intraperitoneally injected with a sesame oil vehicle. The two remaining groups were injected with 50 or 500 mg/kg B.W/day of BPA, resuspended in sesame oil, on either days 7 to 11 or 16 to 20 of pregnancy, with the rats sacrificed on either day 11 or 20, respectively. The mRNA levels of PRL-GH and Pit-1a and b isotype genes were analyzed by Northern blot hybridization and reverse transcription-polymerase chain reaction. The hormone concentrations were analyzed by radioimmunoassay, and the frequency of the placental trophoblast cells observed by a histochemical study. Reproductive data, such as the placental weight and litter size, were surveyed on day 20. The fetal weight was surveyed for 4 weeks after birth. A statistical analysis was carried out using the SAS program (version 8.1). The mRNA levels of the PRL-GH gene family, such as placental lactogen I, Iv and II, prolactin like protein A, C and Cv, and decidual prolactin-related protein were significantly reduced due to BPA exposure. The mRNA levels of the Pit-1a and b isotype genes, which induce the expression of the PRL-GH gene family in the rat placenta, were also reduced due to BPA exposure. The PL-Iv and PL-II concentrations were reduced in the BPA exposed group. During the middle to last stage of pregnancy (Days 11-20), a high dose of BPA exposure reduced the frequency of spongiotrophoblast cells, which are responsible for the secretion of the PRL-GH hormones. Reproductive data, such as the placental and fetal weights and the litter size, were reduced, but that of the pregnancy period was extended in the BPA exposed compared to the control group. BPA disrupts the placental functions in rats, which leads to reproductive disorders.

NTP Studies of Magnetic Field Promotion (DMBA Initiation) in Female Sprague-Dawley Rats (Whole-body Exposure/Gavage Studies).

PubMed

1999-08-01

Electric and magnetic fields are associated with the production, transmission, and use of electricity; thus, the potential for human exposure is high. These elec-tric and magnetic fields are predominantly of low fre-quency (60 Hz in the United States and 50 Hz in Europe) and generally of low intensity. Because some epidemiology studies and initiation/promotion studies in rats have suggested a potential for increased breast cancer rates with increasing magnetic field exposure, the ability of 50- and 60-Hz magnetic fields to pro-mote mammary gland tumors initiated by the administration of 7,12-dimethylbenz(a)anthracene (DMBA) was examined in female Sprague-Dawley rats in 13- and 26-week whole-body exposure studies. Additional animals were evaluated for changes in pineal gland and serum melatonin concentrations. FIRST 13-WEEK STUDY: Groups of 100 female Sprague-Dawley rats were ad-ministered 20 mg DMBA (four weekly gavage doses of 5 mg in sesame oil) and exposed to 1 G 50-Hz, 5 G 50-Hz, or 1 G 60-Hz magnetic fields for 18.5 hours per day, 7 days per week, for 13 weeks. A group of 100 rats administered 20 mg DMBA served as DMBA controls. A group of 100 vehicle control rats was administered only sesame oil on the same schedule. Additional groups of 10 rats receiving similar treatment were evaluated for pineal gland and serum melatonin concentrations at 4, 8, or 12 weeks. All vehicle control rats survived to the end of the study. Of the animals administered 20 mg DMBA, 6 rats in the DMBA control group, 13 in the DMBA/1 G 50-Hz group, eight in the DMBA/5 G 50-Hz group, and five in the DMBA/1 G 60-Hz group died or were removed from the study prior to the final necropsy. Final mean body weights and body weight gains of the DMBA/1 G 50-Hz and DMBA/1 G 60-Hz groups and the mean body weight gain of the DMBA/5 G 50-Hz group were slightly greater than those of the DMBA control group. Clinical findings including torso masses and ulcers (on the mammary masses) were attributed to DMBA administration. The numbers of palpable mammary gland tumors, tumor sizes, and total tumor areas in DMBA/magnetic field groups were similar to those in the DMBA control group. Relative to the DMBA control group, exposure to magnetic fields did not significantly affect overall incidences of mammary gland neoplasms or nonneoplastic lesions in the DMBA/magnetic field groups. SECOND 13-WEEK STUDY: Groups of 100 female Sprague-Dawley rats were ad-ministered 8 mg DMBA (four weekly gavage doses of 2 mg in sesame oil) and exposed to 1 G 50-Hz or 5 G 50-Hz magnetic fields for 18.5 hours per day, 7 days per week, for 13 weeks. A group of 100 female rats administered 8 mg DMBA served as DMBA controls. Additional groups of 10 rats receiving similar treatment were evaluated for pineal gland and serum melatonin concentrations at 4, 8, or 12 weeks. Except for one rat in the DMBA/5 G 50-Hz group, all rats survived until the end of the study. Final mean body weights of DMBA/magnetic field groups were similar to those of the DMBA control group. Clinical findings including torso masses and ulcers were attributed to DMBA administration. The numbers of palpable mammary gland tumors, tumor sizes, and total tumor areas in DMBA/magnetic field groups were similar to those in the DMBA control group. Relative to the DMBA control group, exposure to magnetic fields did not significantly affect overall incidences of mammary gland neoplasms or nonneoplastic lesions in the DMBA/magnetic field groups. 26-WEEK STUDY: Groups of 100 female Sprague-Dawley rats were administered 10 mg DMBA (in sesame oil) by gavage followed by exposure to 1 G 50-Hz, 5 G 50-Hz, or 1 G 60-Hz magnetic fields for 18.5 hours per day, 7 days per week, for 26 weeks. A group of 100 female rats administered 10 mg DMBA served as DMBA controls. Another 100 vehicle control rats were administered only sesame oil. Additional groups of 10 rats receiving similar treatment were evaluated for pineal gland and serum melatonin concentrations at 4, 8, or 12 weeks. All rats in the vehicle control group survived until the end of the study. Twelve rats in the DMBA control group, 15 in the DMBA/1 G 50-Hz group, 9 in the DMBA/5 G 50-Hz group, and six in the DMBA/1 G 60-Hz group died or were removed during the study. The final mean body weights and body weight gains of the DMBA/1 G 50-Hz and DMBA/5 G 50-Hz groups were significantly greater than those of the DMBA control group. Clinical findings including torso masses, abscesses, and ulcers were attributed to DMBA administration. The pineal gland melatonin concentrations of DMBA/5 G 50-Hz and DMBA/1 G 60-Hz rats were significantly greater than that of the DMBA controls at week 12; however, these data were highly variable between individual animals within each group. The numbers of palpable mammary gland tumors, tumor sizes, and total tumor areas in DMBA/magnetic field groups were similar to those in the DMBA controls. The incidences of mammary gland carci-noma (including multiple) in the DMBA/1 G 60-Hz group were significantly decreased relative to the DMBA control group. CONCLUSIONS: In an initiation/promotion study in which female Sprague-Dawley rats were initiated by four weekly doses of 5 mg DMBA per rat beginning at 50 days of age and exposed to 50-Hz magnetic fields at 1 or 5 G field intensities or to 1 G 60-Hz magnetic fields for 13 weeks, there was no evidence that magnetic fields promoted the development of mammary gland neoplasms. The prevalence and multiplicity of mammary gland carcinomas in all DMBA groups limited the ability of this assay to detect a promoting effect of magnetic fields. In an initiation/promotion study in which female Sprague-Dawley rats were initiated by four weekly doses of 2 mg DMBA per rat beginning at 50 days of age and exposed to 50-Hz magnetic fields at 1 or 5 G field intensities for 13 weeks, there was no evidence that magnetic fields promoted the development of mammary gland neoplasms. In an initiation/promotion study in which female Sprague-Dawley rats were initiated by a single 10 mg DMBA dose at 50 days of age and then exposed to 50-Hz magnetic fields at 1 or 5 G field intensities or to 1 G 60-Hz magnetic fields for 26 weeks, there was no evidence that magnetic fields promoted the development of mammary gland neoplasms.