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Sample records for severe sliding conditions

  1. Friction and Wear Behavior of Silicon Under Conditions of Sliding.

    NASA Astrophysics Data System (ADS)

    Nadimpalli, Chandrasekhar Venkata

    Silicon is gaining importance as a material in micromechanical applications such as micromotors and microactuators. Friction and wear can affect the performance of these devices and hence it is important to study the friction and wear behavior of silicon. The deformation behavior of n-type silicon is fundamentally different from p-type. On deformation, n -type silicon may convert to p-type, but p-type silicon does not convert to n-type on deformation. This is related to the effect of dislocations interacting with the electrical charge carriers. Friction and wear behavior of n and p-type silicon was studied under conditions of sliding wear. Sliding was selected because the stress system associated with sliding introduces large plastic strains at the surface. The friction and wear behavior of n and p-type silicon is expected to be different due to the differences in their deformation behavior. Also, the n to p transition may show up in the friction and wear behavior. The samples were tested in air and in vacuum. Diamond was used as the slider. The wear tracks showed evidence of plastic flow. The morphology of this material was similar to that seen in more ductile materials. The coefficient of friction was also high. Other researchers have reported that DC Silicon transforms to a more ductile phase when sufficient pressure is applied. When shear stresses are present, as in sliding wear, the pressure for phase transformation has been reported to be about 8 GPa. The maximum pressure under the slider in the present set of experiments was estimated to be 8.2 GPa. Therefore, it is possible that transformed material extruded during sliding to produce the flow-like features observed at the wear track. The work involved in this phase transformation, as well as the work in deforming DC Silicon and/or the ductile product phase would contribute to the frictional energy. The debris from the air tests was DC silicon (as determined by XRD and TEM). No significant differences were

  2. Effect of starvation on film thickness and traction under elastohydrodynamic rolling and sliding conditions

    NASA Technical Reports Server (NTRS)

    Wedeven, L. D.

    1975-01-01

    Traction measurements under starved elastohydrodynamic conditions were obtained for a point-contact geometry. Simultaneous measurements of the film thickness and the location of the inlet lubricant boundary were made. Optical interferometry was used to measure film thickness. The thickness of a starved film for combined rolling and sliding conditions varies with the location of the inlet boundary in the same way as previously found for pure rolling conditions. When the fluid velocity distribution is calculated in the inlet region by a Reynolds lubrication analysis, backflow is seen to occur over a portion of the inlet region. Backflow is essential for the establishment of a flooded condition. The location of certain fluid velocity conditions within the inlet region, as suggested in the literature, does not adequately describe the onset of starvation. For the same slide-roll ratio a starved film was observed to possess greater traction than a flooded film. Traction measurements under starved conditions were also compared with those under flooded conditions for equivalent shear rates in the Hertzian region. When the shear rates within the Hertzian region were low and the film was severely starved, the measured tractions were lower than expected. This may be due to large shear stresses developed by the large pressure gradients that are generated in the inlet region when it is severely starved.

  3. Reaction of perfluoroalkylpolyethers (PFPE) with 440C steel in vacuum under sliding conditions at room temperature

    NASA Technical Reports Server (NTRS)

    Mori, Shigeyuki; Morales, Wilfredo

    1989-01-01

    Reactions of perfluoroalkylpolyethers (PFPE: Fomblin, Demnum and Krytox) were studied during the sliding contact of stainless steel specimens under ultrahigh vacuum conditions. All three fluids reacted with the steel specimens during sliding. Fomblin, which has acetal linkages, decomposed under the sliding conditions generating gaseous products, (COF2 and fluorinated carbons) which were detected by a quadrupole mass spectrometer. Gaseous products were not detected for the Demnum and Krytox fluids. The amount of gaseous products from Fomblin increased with increasing sliding speed. At the end of the sliding experiments, the wear scar and deposits on the specimens were examined by small spot size XPS. The oxide layer on the specimen surface was removed during sliding, and metal fluorides were formed on the worn surface. The surface of the wear scar and deposits were covered with adsorbed PFPE. Based on these results, it was concluded that the decomposition reaction on Fomblin was initiated by contacting the fluid with a fresh metal surface which was formed during sliding.

  4. XPS analysis of 440C steel surfaces lubricated with perfluoropolyethers under sliding conditions in high vacuum

    NASA Technical Reports Server (NTRS)

    Herrera-Fierro, Pilar; Masuko, Masabumi; Jones, William R., Jr.; Pepper, Stephen V.

    1994-01-01

    This work presents the results of the X-Ray Photoelectron Spectroscopy (XPS) analysis of AISI 440C ball surfaces lubricated with perfluoropolyether (PFPE) oils after friction experiments under sliding conditions at high load in air and vacuum environments. The PFPE lubricants tested were Demnum S100, Fomblin Z-25, and Krytox 143AB. It was found that all the PFPE lubricants were degraded by sliding contact causing the formation of inorganic fluorides on the metallic surfaces and a layer of organic decomposition products. KRYTOX 143AB was the least reactive of the three lubricants tested. It was also found that metal fluoride formed at off-scar areas. This suggests the formation of reactive species, such as COF2 or R(sub f)COF, during sliding experiments, which can diffuse through the lubricant film and react with the metallic surfaces away from the contact region. Comparison of reference specimens before sliding with those that had undergone the sliding tests showed that the amount of non-degraded PFPE remaining on the surface of the balls after the sliding experiments was greater than that of the balls without sliding.

  5. Healing and Shear Stress Reduction on Single Fracture of Rock Salt and Limestone under Slide-Hold-Slide Direct Shear Condition

    NASA Astrophysics Data System (ADS)

    Kishida, K.; Yano, T.; Yasuhara, H.

    2012-12-01

    In order to clarify the influence of the holding state on the shear strength in the shear process of a single rock fracture, slide-hold-slide (SHS) direct shear-flow coupling tests were carried out on single rock fractures at several confining stresses and under saturated/unsaturated conditions (Kishida, et al., 2011). Consequently, the mortar specimen could be confirmed as the significant shear strength recovery on the SHS process. In this research, the SHS direct shear tests are carried out on the halite (rock salt) and the limestone. In the case of rock salt, a single tensile fracture is artificially created by cutting away. On the other hand, the limestone has a natural rock joint. The experiments are carried out under various normal confining stress conditions and are employed various holding period at the residual state. Figure 1 shows the shear stress - shear displacement of the SHS direct shear experiments on the rock salt. From all cases, the shear stress increases at the initial phase of the experiments, and then, the shear stress reaches at the peak shear strength. After that, the shear stress slightly decreases such as strain softening. Finally, the shear stress reaches to the residual stress state. In every SHS processes, the shear stress is reducing in various hold period. And then, the shear stress is increasing in the process of re-sliding. The shear stress in the process of re-sliding takes over the value at the start time of the holding process. The shear stress reaches at the peak, and then, it reaches the residual stress state. In all cases, as the holding period becomes longer, it is confirmed that the decrement of the shear stress in the holding process is increasing and the increment of the shear stress at the re-sliding process is increasing. Therefore, it is confirmed that the time dependence of shear strength recovery can be observed. In addition, Dieterich's A constant value for the regression lines (Dieterich, 1972, 1994) is plotted

  6. Onset of frictional sliding of rubber–glass contact under dry and lubricated conditions

    PubMed Central

    Tuononen, Ari J.

    2016-01-01

    Rubber friction is critical in many applications ranging from automotive tyres to cylinder seals. The process where a static rubber sample transitions to frictional sliding is particularly poorly understood. The experimental and simulation results in this paper show a completely different detachment process from the static situation to sliding motion under dry and lubricated conditions. The results underline the contribution of the rubber bulk properties to the static friction force. In fact, simple Amontons’ law is sufficient as a local friction law to produce the correct detachment pattern when the rubber material and loading conditions are modelled properly. Simulations show that micro-sliding due to vertical loading can release initial shear stresses and lead to a high static/dynamic friction coefficient ratio, as observed in the measurements. PMID:27291939

  7. The Influence of Sliding and Contact Severity on the Generation of White Etching Cracks

    SciTech Connect

    Gould, Benjamin; Greco, Aaron

    2015-10-17

    White etching cracks (WECs) have been identified as the dominant mechanism of premature failure for bearings within wind turbine gearboxes. Though WECs have been observed in the field for over a decade, the exact mechanisms which lead to this failure are still debated, and benchtop replication has proven difficult. In previously published work, WECs have been replicated only through the use of component level test rigs, where complete bearings are tested. In these tests, the factors that are thought to drive the formation of WECs, such as slide-to-roll ratio (SRR) and lubricant film thickness, cannot not be easily altered or controlled. In this paper, WECs have been replicated on a three rings on roller, benchtop test rig, which allowed for a direct investigation into the influence that SRR magnitude, sliding direction, and the lubricant film thickness have on surface failures and WEC generation. It was determined that WEC were formed in samples that experienced -30% SRR at various lubrication conditions, however, at lower levels of negative SRR and positive SRR up to 30% no white-etching cracks were observed.

  8. Finite element analysis of sliding distance and contact mechanics of hip implant under dynamic walking conditions.

    PubMed

    Gao, Yongchang; Jin, Zhongmin; Wang, Ling; Wang, Manyi

    2015-06-01

    An explicit finite element method was developed to predict the dynamic behavior of the contact mechanics for a hip implant under normal walking conditions. Two key parameters of mesh sensitivity and time steps were examined to balance the accuracy and computational cost. Both the maximum contact pressure and accumulated sliding distance showed good agreement with those in the previous studies using the implicit finite element analysis and analytical methods. Therefore, the explicit finite element method could be used to predict the contact pressure and accumulated sliding distance for an artificial hip joint simultaneously in dynamic manner.

  9. Friction and wear of rare earths modified carbon fibers filled PTFE composite under dry sliding condition

    NASA Astrophysics Data System (ADS)

    Qian-qian, Shangguan; Xian-hua, Cheng

    2007-09-01

    Carbon fibers (CF) were surface treated with air-oxidation and rare earths (RE), respectively. The friction and wear properties of polytetrafluoroethylene (PTFE) composites filled with differently surface treated carbon fibers, sliding against GCr15 steel under dry sliding condition, were investigated on a block-on-ring M-2000 tribometer. Experimental results revealed that RE treatment largely reduced the friction and wear of CF reinforced PTFE (CF/PTFE) composites. The RE treated composite exhibited the lowest friction and wear under dry sliding. Scanning electron microscopy (SEM) investigation of worn surfaces and transfer films of CF/PTFE composites showed that RE treated CF/PTFE composites had the smoothest worn surface under given load and sliding speed, and a continuous and uniform transfer film formed on the counterface. X-ray photoelectron spectroscopy (XPS) study of carbon fiber surface showed that the oxygen concentration was obviously increased after RE treatment, and more carboxyl groups were introduced onto CF surfaces after RE treatment. The increase in the amount of oxygen-containing groups increased the interfacial adhesion between CF and PTFE matrix, and accordingly increased the tribological properties of the composite.

  10. Impact of pavement conditions on crash severity.

    PubMed

    Li, Yingfeng; Liu, Chunxiao; Ding, Liang

    2013-10-01

    Pavement condition has been known as a key factor related to ride quality, but it is less clear how exactly pavement conditions are related to traffic crashes. The researchers used Geographic Information System (GIS) to link Texas Department of Transportation (TxDOT) Crash Record Information System (CRIS) data and Pavement Management Information System (PMIS) data, which provided an opportunity to examine the impact of pavement conditions on traffic crashes in depth. The study analyzed the correlation between several key pavement condition ratings or scores and crash severity based on a large number of crashes in Texas between 2008 and 2009. The results in general suggested that poor pavement condition scores and ratings were associated with proportionally more severe crashes, but very poor pavement conditions were actually associated with less severe crashes. Very good pavement conditions might induce speeding behaviors and therefore could have caused more severe crashes, especially on non-freeway arterials and during favorable driving conditions. In addition, the results showed that the effects of pavement conditions on crash severity were more evident for passenger vehicles than for commercial vehicles. These results provide insights on how pavement conditions may have contributed to crashes, which may be valuable for safety improvement during pavement design and maintenance. Readers should notice that, although the study found statistically significant effects of pavement variables on crash severity, the effects were rather minor in reality as suggested by frequency analyses.

  11. 76 FR 26957 - Special Conditions: Boeing, Model 747-8 Series Airplanes; Door 1 Extendable Length Escape Slide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... part 34 and the noise certification requirements of 14 CFR part 36. Special conditions, as defined in... end. The airplane is equipped with an electronic sensor that evaluates the attitude of the airplane... slide in its normal attitude and will ensure that the slide can function in its extended mode at...

  12. Effect of Operating Conditions on Tribological Response of Al Al Sliding Electrical Interface

    SciTech Connect

    Bansal, Dinesh G; Streator, Jeffrey L

    2011-01-01

    Aluminum is widely used in electrical contacts due to its electrical properties and inexpensiveness when compared to copper. In this study, we investigate the influence of operating conditions like contact load (pressure), sliding speed, current, and surface roughness on the electrical and tribological behavior of the interface. The tests are conducted on a linear, pin-on-flat tribo-simulator specially designed to investigate electrical contacts under high contact pressures and high current densities. Control parameters include sliding speed, load, current, and surface roughness. The response of the interface is evaluated in the light of coefficient of friction, contact resistance, contact voltage, mass loss of pins, and interfacial temperature rise. As compared to sliding speed, load, and roughness, current is found to have the greatest influence on the various measured parameters. Under certain test conditions, the interface operates in a voltage saturation regime, wherein increase in current do not result in any increase in contact voltage. Within the voltage saturation regime the coefficient of friction tends to be lower, a result that is attributed to the higher temperatures associated with the higher voltage (and resulting material softening). Higher interfacial temperatures also appear to be responsible for the higher wear rates observed at higher current levels as well as lower coefficients of friction for smoother surfaces in the presence of current.

  13. Debris and 1/f noise in sliding friction dynamics under wear conditions

    NASA Astrophysics Data System (ADS)

    Vragovic, I.; Molina, J. M.; Prieto, R.; Duarte, M.; Narciso, J.; Louis, E.

    2009-12-01

    Friction force time series showing irregular fluctuations have been since long considered one of the possible stick-slip regimes in sliding friction. However, it has not been until recently that a 1/f power spectrum in friction force time series derived from sliding friction experiments under wear conditions has been identified. A variety of models, mostly inspired in the field of earthquakes, has been explored, without reaching a fully satisfactory explanation of that behavior. Recently, the present authors have reported results of sliding friction experiments on steel with alumina pins, carried out with and without debris blowing, that proved the role of loose debris in determining the 1/f character of the friction force. A damped-forced harmonic oscillator with two friction terms was proposed to describe the dynamics of friction under wear conditions: one purely random, which accounts for surface roughness, and another inversely proportional to the amount of loose debris that was calculated by means of a modified sand-pile model. This paper presents a full discussion of the experiments that allowed to reach that conclusion and of the model proposed to rationalize the results. In addition, the results of experiments devised to understand the transition from friction with debris to friction without debris (experiment initiated without blowing and after some time switching on blowing) and vice versa are reported. The results of further studies of the wear track are presented, namely, the variation in the track width with sliding distance and results of chemical analyses and surface roughness measurements of the track, for both with or without debris blowing experiments. These additional data give further support to the crucial role of debris in the 1/f character of the friction force.

  14. Sliding behavior of calcite and dolomite marbles at seismic deformation conditions

    NASA Astrophysics Data System (ADS)

    Spagnuolo, E.; Smith, S. A.; Niemeijer, A. R.; di Toro, G.; Nielsen, S.

    2010-12-01

    Our understanding of earthquake physics is hampered by the poor knowledge of the evolution of the friction coefficient in rocks (µ or the ratio of shear stress over normal stress) at deformation conditions typical of the seismic source (normal stress > 40 MPa, slip rates > 1 m/s, abrupt accelerations, etc.). Insights can be gained by experiments using a novel rotary shear deformation apparatus, SHIVA (Slow to HIgh Velocity Apparatus) which, by exploiting the large available power (300 kW), is capable of extending the performance of previous experimental apparatus to more realistic (i.e., approaching natural) conditions. Here we present results from experiments performed on samples of Carrara (98% calcite) and dolomite (98% dolomite) marbles. The two rocks were selected because many earthquakes worldwide nucleate within and rupture through carbonates sequences (e.g., L’Aquila 2009 Mw 6.3). Tests were conducted on hollow cylinders (50/30 mm ext/int diameter) at velocities of 0.001-6.5 m/s and normal stresses up to 40 MPa. Each experiment consists of three steps: (1) loading of the sample to the target normal stress; (2) acceleration to the imposed slip rate; (3) deceleration until the target slip or duration is reached. The two marbles show a similar evolution of friction: µ rapidly increases to reach an initial peak value (~ 0.6) followed by a dramatic reduction towards an extremely low steady-state value (< 0.1), comparable to previous experiments performed at lower normal stresses (< 13 MPa). For both rock-types experiments with multiple slip pulses separated by short periods of no sliding (i.e. slide-hold-slide tests) show that the initial peak friction upon re-sliding increases significantly with hold time, while the steady state friction remains roughly the same. Steady-state friction of calcite is slightly lower than that of dolomite. The dramatic reduction in friction occurs over a slip weakening distance in the range 0.4-2.5 m for calcite and 0.1-0.4 m

  15. Auger spectroscopy analysis of lubrication with zinc dialkyldithiophosphate of several metal combinations in sliding contact

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1979-01-01

    Sliding friction experiments were conducted with aluminum and other riders rubbing on disks of various elemental metals in the presence of a thin film of zinc dialkyldithiophosphate (ZDP). Auger emission spectroscopy was used to in situ monitor the changes in surface chemistry with rubbing under various loads. The metal disks examined included iron, titanium, rhodium, tungsten, molybdenum, and copper. For equivalent films of ZDP the film is a more effective lubricant for some metals than it is for others. The important active element in the compound varies with the metal lubricated and is a function of metal chemistry. The zinc in the ZDP is susceptible to electron beam induced desorption.

  16. Sliding-window analysis tracks fluctuations in amygdala functional connectivity associated with physiological arousal and vigilance during fear conditioning.

    PubMed

    Baczkowski, Blazej M; Johnstone, Tom; Walter, Henrik; Erk, Susanne; Veer, Ilya M

    2017-03-12

    We evaluated whether sliding-window analysis can reveal functionally relevant brain network dynamics during a well-established fear conditioning paradigm. To this end, we tested if fMRI fluctuations in amygdala functional connectivity (FC) can be related to task-induced changes in physiological arousal and vigilance, as reflected in the skin conductance level (SCL). Thirty-two healthy individuals participated in the study. For the sliding-window analysis we used windows that were shifted by one volume at a time. Amygdala FC was calculated for each of these windows. Simultaneously acquired SCL time series were averaged over time frames that corresponded to the sliding-window FC analysis, which were subsequently associated with the whole-brain seed-based amygdala sliding-window FC using the GLM. Surrogate time series were generated to test whether connectivity dynamics could have occurred by chance. In addition, results were contrasted against static amygdala FC and sliding-window FC of the primary visual cortex, which was chosen as a control seed, while a physio-physiological interaction (PPI) was performed as cross-validation. During periods of increased SCL, the left amygdala became more strongly coupled with the bilateral insula and medial prefrontal cortex, core areas of the salience network. The sliding-window analysis yielded a connectivity pattern that was unlikely to have occurred by chance, was spatially distinct from static amygdala FC and from sliding-window FC of the primary visual cortex, but was highly comparable to that of the PPI analysis. We conclude that sliding-window analysis can reveal functionally relevant fluctuations in connectivity in the context of an externally cued task.

  17. Piecewise-diffeomorphic image registration: application to the motion estimation between 3D CT lung images with sliding conditions.

    PubMed

    Risser, Laurent; Vialard, François-Xavier; Baluwala, Habib Y; Schnabel, Julia A

    2013-02-01

    In this paper, we propose a new strategy for modelling sliding conditions when registering 3D images in a piecewise-diffeomorphic framework. More specifically, our main contribution is the development of a mathematical formalism to perform Large Deformation Diffeomorphic Metric Mapping registration with sliding conditions. We also show how to adapt this formalism to the LogDemons diffeomorphic registration framework. We finally show how to apply this strategy to estimate the respiratory motion between 3D CT pulmonary images. Quantitative tests are performed on 2D and 3D synthetic images, as well as on real 3D lung images from the MICCAI EMPIRE10 challenge. Results show that our strategy estimates accurate mappings of entire 3D thoracic image volumes that exhibit a sliding motion, as opposed to conventional registration methods which are not capable of capturing discontinuous deformations at the thoracic cage boundary. They also show that although the deformations are not smooth across the location of sliding conditions, they are almost always invertible in the whole image domain. This would be helpful for radiotherapy planning and delivery.

  18. Characterization of Wear Particles Generated from CoCrMo Alloy under Sliding Wear Conditions

    PubMed Central

    Pourzal, R.; Catelas, I.; Theissmann, R.; Kaddick, C.; Fischer, A.

    2011-01-01

    Biological effects of wear products (particles and metal ions) generated by metal-on-metal (MoM) hip replacements made of CoCrMo alloy remain a major cause of concern. Periprosthetic osteolysis, potential hypersensitivity response and pseudotumour formation are possible reactions that can lead to early revisions. To accurately analyse the biological response to wear particles from MoM implants, the exact nature of these particles needs to be characterized. Most previous studies used energy-dispersive X-ray spectroscopy (EDS) analysis for characterization. The present study used energy filtered transmission electron microscopy (TEM) and electron diffraction pattern analysis to allow for a more precise determination of the chemical composition and to gain knowledge of the crystalline structure of the wear particles. Particles were retrieved from two different test rigs: a reciprocating sliding wear tribometer (CoCrMo cylinder vs. bar) and a hip simulator according to ISO 14242-1 (CoCrMo head vs. CoCrMo cup). All tests were conducted in bovine serum. Particles were retrieved from the test medium using a previously published enzymatic digestion protocol. Particles isolated from tribometer samples had a size of 100 – 500 nm. Diffraction pattern analysis clearly revealed the lattice structure of strain induced hcp ε-martensite. Hip simulator samples revealed numerous particles of 15 – 30 nm and 30 – 80 nm size. Most of the larger particles appeared to be only partially oxidized and exhibited cobalt locally. The smallest particles were Cr2O3 with no trace of cobalt. It optically appeared that these Cr2O3 particles were flaking off the surface of larger particles that depicted a very high intensity of oxygen, as well as chromium, and only background noise of cobalt. The particle size difference between the two test rigs is likely related to the conditions of the two tribosystems, in particular the difference in the sample geometry and in the type of sliding

  19. Boundary conditions in the vicinity of a dynamic contact line: experimental investigation of viscous drops sliding down an inclined plane.

    PubMed

    Rio, E; Daerr, A; Andreotti, B; Limat, L

    2005-01-21

    To probe the microscopic balance of forces close to a moving contact line, the boundary conditions around viscous drops sliding down an inclined plane are investigated. At first, the variation of the contact angle as a function of the scale of analysis is discussed. The dynamic contact angle is measured at a scale of 6 mum all around sliding drops for different volumes and speeds. We show that it depends only on the capillary number based on the local liquid velocity, measured by particle tracking. This velocity turns out to be normal to the contact line everywhere. It indirectly proves that, in comparison with the divergence involved in the normal direction, the viscous stress is not balanced by intermolecular forces in the direction tangential to the contact line, so that any motion in this last direction gets damped.

  20. Selected Landscape Plants. Slide Script.

    ERIC Educational Resources Information Center

    McCann, Kevin

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with commercially important woody ornamental landscape plants. Included in the script are narrations for use with a total of 253 slides illustrating 92 different plants. Several slides are used to illustrate each plant: besides a view of…

  1. Unravelling the multiphase run-out conditions of a slide-flow mass movement

    NASA Astrophysics Data System (ADS)

    van Asch, Th. W. J.; Xu, Q.; Dong, X. J.

    2015-02-01

    In this paper an attempt is made to unravel the run-out characteristics of a mass movement in the Sichuan Province, SW China by means of 1D numerical modelling and calibration on the topography of run-out profiles. The Dagou mass movement started as a rockslide with an initial volume of 480,000 m3, which transformed into a debris flow, increasing in volume due to entrainment of loose material in the upper part of the travelling track. The rapid mass movement had a run-out distance of 1380 m and a run-out time of about 50 s. Numerical calculations were conducted with the depth average shallow water equation to explain the variation in thickness of the debris flow deposits along the run-out track. For the calibration of the first run-out phase, three rheological models were applied, namely the Bingham, Voellmy and Quadratic rheology. Calibration was done on 1) the run-out distance, 2) the run-out time and 3) the goodness of fit with the thickness of the deposits along the track. In addition the erosion constant in the entrainment equation was calibrated on the observed versus calculated run-out volumes. Sensitivity analyses of the resistance parameters for the different rheologies showed that the viscosity, the basal friction, the turbulence term and the resistance factor are the most sensitive ones. It appeared that the variation in thickness along the run-out track can be explained by entrainment of material in the upper part of the track and a change in parametric values during the run-out process. The three rheologies produced a reasonable fit with the observed geometry of the run-out profile, run-out time and run-out volume. It was argued that the Voellmy rheology seems to give the most appropriate explanation for the difference in resistance along the run-out path. The main problem in the simulation was to stop the debris flow on a slope with a gradient around 22°. A reactivation of the mass movement by frictional sliding of the material half way the run

  2. The Effect of Carbides Precipitation on the Sliding Wear Characteristics According to Heat Treatment Conditions

    NASA Astrophysics Data System (ADS)

    Suh, Chang-Min; Choi, Gye-Won; Kim, Kyung-Ryul; Han, Moon-Sik

    This study investigated the effect of carbide precipitation hardening of heat-treated SK5M steel on the sliding wear resistance. The cold rolled carbon steel strip samples (J, G, and S-type) were oil quenched after tempering for optimal durations. The wear resistance was evaluated using a pin-on-disk wear test with an alumina counterface against different samples at various loads and distances with a constant running speed. The size and distribution of the precipitated carbides were observed using an image analyzer at various heat treatments. The heat-treated samples presented more dense carbide distribution in an area fraction and the decreased size of carbides. It is confirmed that the wear rate is minimum at an optimized austenitizing temperature of around 800°C. The specific wear rate indicates that the S-type sample has high wear resistance compared to that of J-Type. This is understood by stable wear behavior of S-type sample containing evenly distributed carbide precipitation.

  3. Investigation of Wear and Friction Properties Under Sliding Conditions of Some Materials Suitable for Cages of Rolling-Contact Bearings

    NASA Technical Reports Server (NTRS)

    Johnson, Robert L; Swikert, Max A; Bisson, Edmond E

    1952-01-01

    An investigation of wear and friction properties of a number of materials sliding against SAE 52100 steel was conducted. These materials included brass, bronze, beryllium copper, monel, nichrome v, 24s-t aluminum, nodular iron, and gray cast iron. The metals investigated may be useful as possible cage (separator or retainer) materials for rolling-contact bearings of high-speed turbine engines. The ability of materials to form surface films that prevent welding is a most important factor in both dry friction and boundary lubrication. On the basis of wear and resistance to welding only, the cast irons were the most promising materials investigated; they showed the least wear and the least tendency to surface failure when run dry, and when boundary lubricated they showed the highest load capacity. On the basis of mechanical properties, nodular iron is superior to gray cast iron. Bronze had the lowest friction coefficient under dry sliding conditions. The results with brass, beryllium copper, and aluminum were poor and these materials do not appear, with regard to friction and wear, to be suitable for cages.

  4. GLACIER SLIDING,

    DTIC Science & Technology

    The theory of the sliding of glaciers presented in earlier papers has been generalized (1) by taking into account the resistance to sliding offered...bed at the downstream side of an obstacle. The sliding velocities and controlling obstacle sizes which are found from the generalized theory are...magnitude smaller in thickness than the height of the controlling obstacles can cause an appreciable increase in the sliding velocity. The generalized

  5. Effect of bionic coupling units' forms on wear resistance of gray cast iron under dry linear reciprocating sliding condition

    NASA Astrophysics Data System (ADS)

    Pang, Zuobo; Zhou, Hong; Xie, Guofeng; Cong, Dalong; Meng, Chao; Ren, Luquan

    2015-07-01

    In order to get close to the wear form of guide rails, the homemade linear reciprocating wear testing machine was used for the wear test. In order to improve the wear-resistance of gray cast iron guide rail, bionic coupling units of different forms were manufactured by a laser. Wear behavior of gray-cast-iron with bionic-coupling units has been studied under dry sliding condition at room temperature using the wear testing machine. The wear resistance was evaluated by means of weight loss measurement and wear morphology. The results indicated that bionic coupling unit could improve the wear resistance of gray cast iron. The wear resistance of gray cast iron with reticulation bionic coupling unit is the best. When the load and speed changed, reticulation bionic coupling unit still has excellent performance in improving the wear resistance of gray cast iron.

  6. CCTV Data Management for Effective Condition Assessment of Wastewater Collection Systems - slides

    EPA Science Inventory

    The project objectives are: Research current state of condition assessment technology for wastewater collection systems; Evaluate performance and cost of innovative and advanced infrastructure monitoring technologies; Identify and evaluate innovative CCTV technologies; and Prepar...

  7. EPA Field Demonstration of Innovative Condition Assessment Technologies for Water Mains at Louisville, KY - slides

    EPA Science Inventory

    This presentation will describe a series of field demonstrations of innovative leak detection/location and condition assessment technologies that was sponsored by the U.S. Environmental Protection Agency (EPA), conducted by EPA’s contractor (Battelle), and hosted by the Louisvill...

  8. Ultra-high temperature tensile properties of ODS steel claddings under severe accident conditions

    NASA Astrophysics Data System (ADS)

    Yano, Y.; Tanno, T.; Oka, H.; Ohtsuka, S.; Inoue, T.; Kato, S.; Furukawa, T.; Uwaba, T.; Kaito, T.; Ukai, S.; Oono, N.; Kimura, A.; Hayashi, S.; Torimaru, T.

    2017-04-01

    Ultra-high temperature ring tensile tests were performed to investigate the tensile behavior of oxide dispersion strengthened (ODS) steel claddings and wrapper materials under severe accident conditions with temperatures ranging from room temperature to 1400 °C which is close to the melting point of core materials. The experimental results showed that the tensile strength of 9Cr-ODS steel claddings was highest in the core materials at ultra-high temperatures of 900-1200 °C, but there was significant degradation in the tensile strength of 9Cr-ODS steel claddings above 1200 °C. This degradation was attributed to grain boundary sliding deformation with γ/δ transformation, which is associated with reduced ductility. By contrast, the tensile strength of recrystallized 12Cr-ODS and FeCrAl-ODS steel claddings retained its high value above 1200 °C, unlike the other tested materials.

  9. Conditions for Two-Cell Structure in Severe Vortical Storms.

    DTIC Science & Technology

    1984-02-01

    SEVERE VORTICAL STORMS by G. F. Carrier, F. E. Fendell , P. S. Feldman, and S. F. Fink TRW Space and Technology Group, Redondo Beach, CA 90278 Thi...Claification Conditions for Two-Call Structure in Severe Vortical Storms (U) 12. PERSONAL AUTHOR(S) Carrier. G. F. (Harvard U.): Fendell , F. E., Feldman...cell structure will occur. Very roughly, about half of all tropical storms ( Fendell 1974), and about one-quarter to one-half of meso- cyclones (Brooks

  10. Reciprocating sliding wear behavior of alendronate sodium-loaded UHMWPE under different tribological conditions.

    PubMed

    Huang, Jie; Qu, Shuxin; Wang, Jing; Yang, Dan; Duan, Ke; Weng, Jie

    2013-07-01

    The aim of this study is to investigate the tribological behaviors and wear mechanisms of ultra-high molecular weight polyethylene (UHMWPE) loaded with alendronate sodium (ALN), a potential drug to treat osteolysis, under different normal loads and lubrication conditions. A mixture of UHMWPE powder and ALN (1.0 wt.%) solution was dried and hot pressed. The static and dynamic friction coefficients of UHMWPE-ALN were slightly higher than those of UHMWPE except under normal load as 10 N and in 25 v/v % calf serum. The specific wear rates of UHMWPE-ALN and UHMWPE were the lowest in 25 v/v % calf serum compared to those in deionized water or physiological saline. In particular, the specific wear rate of UHMWPE-ALN was lower than that of UHMWPE at 50 N in 25 v/v % calf serum. The main wear mechanisms of UHMWPE and UHMWPE-ALN in deionized water and UHMWPE in physiological saline were abrasive. The main wear mechanism of UHMWPE-ALN in physiological saline was micro-fatigue. In 25 v/v % calf serum, the main wear mechanism of UHMWPE and UHMWPE-ALN was abrasive wear accompanied with plastic deformation. The results of Micro-XRD indicated that the molecular deformation of UHMWPE-ALN and UHMWPE under the lower stress were in the amorphous region but in the crystalline region at the higher stress. These results showed that the wear of UHMWPE-ALN would be reduced under calf serum lubricated, which would be potentially applied to treat osteolysis.

  11. Full-length fuel rod behavior under severe accident conditions

    SciTech Connect

    Lombardo, N J; Lanning, D D; Panisko, F E

    1992-12-01

    This document presents an assessment of the severe accident phenomena observed from four Full-Length High-Temperature (FLHT) tests that were performed by the Pacific Northwest Laboratory (PNL) in the National Research Universal (NRU) reactor at Chalk River, Ontario, Canada. These tests were conducted for the US Nuclear Regulatory Commission (NRC) as part of the Severe Accident Research Program. The objectives of the test were to simulate conditions and provide information on the behavior of full-length fuel rods during hypothetical, small-break, loss-of-coolant severe accidents, in commercial light water reactors.

  12. 24 CFR 3285.404 - Severe climatic conditions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....404 Severe climatic conditions. In frost-susceptible soil locations, ground anchor augers must be installed below the frost line, unless the foundation system is frost-protected to prevent the effects of frost heave, in accordance with acceptable engineering practice and § 3280.306 of this chapter...

  13. 24 CFR 3285.404 - Severe climatic conditions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....404 Severe climatic conditions. In frost-susceptible soil locations, ground anchor augers must be installed below the frost line, unless the foundation system is frost-protected to prevent the effects of frost heave, in accordance with acceptable engineering practice and § 3280.306 of this chapter...

  14. 24 CFR 3285.404 - Severe climatic conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....404 Severe climatic conditions. In frost-susceptible soil locations, ground anchor augers must be installed below the frost line, unless the foundation system is frost-protected to prevent the effects of frost heave, in accordance with acceptable engineering practice and § 3280.306 of this chapter...

  15. 24 CFR 3285.404 - Severe climatic conditions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ....404 Severe climatic conditions. In frost-susceptible soil locations, ground anchor augers must be installed below the frost line, unless the foundation system is frost-protected to prevent the effects of frost heave, in accordance with acceptable engineering practice and § 3280.306 of this chapter...

  16. 24 CFR 3285.404 - Severe climatic conditions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....404 Severe climatic conditions. In frost-susceptible soil locations, ground anchor augers must be installed below the frost line, unless the foundation system is frost-protected to prevent the effects of frost heave, in accordance with acceptable engineering practice and § 3280.306 of this chapter...

  17. Prototype Slide Stainer

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The prototype slide staining system capable of performing both one-component Wright's staining of blood smears and eight-step Gram staining of heat fixed slides of microorganisms is described. Attention was given to liquid containment, waste handling, absence of contamination from previous staining, and stability of the staining reagents. The unit is self-contained, capable of independent operation under one- or zero-g conditions, and compatible with Skylab A.

  18. Exploring novel sero-epidemiological tools-Effect of different storage conditions on longitudinal stability of microarray slides comprising influenza A-, measles- and Streptococcus pneumoniae antigens.

    PubMed

    Freidl, Gudrun; Bruin, Erwin de; Schipper, Maarten; Koopmans, Marion

    2017-03-15

    In this study we evaluated the long-term stability of a microarray-based serological screening platform, containing antigens of influenza A, measles and Streptococcus pneumoniae, as part of a preparedness research program aiming to develop assays for syndromic disease detection. Spotted microarray slides were kept at four different storage regimes with varying temperature and humidity conditions. We showed that under the standard storage condition in a temperature-controlled (21°C) and desiccated environment (0% relative humidity), microarray slides remained stable for at least 22 months without loss of antigen quality, whereas the other three conditions (37°C, desiccated; Room temperature, non-desiccated; Frozen, desiccated) produced acceptable results for some antigens (influenza A, S.pneumoniae), but not for others (measles). We conclude that these arrays for multiplex antibody testing can be prepared and stored for prolonged periods of time, which aids laboratory-preparedness and facilitates sero-epidemiological studies.

  19. 76 FR 38550 - Special Conditions: Boeing, Model 747-8 Series Airplanes; Door 1 Extendable Length Escape Slide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... a derivative of the 747-400. The Model 747-8 is a four-engine jet transport airplane that will have a maximum takeoff weight of 975,000 pounds, new General Electric GEnx -2B67 engines, and the... extension packed at the toe end of the escape slide. During normal operation, the extension portion...

  20. Analysis of concrete containment structures under severe accident loading conditions

    SciTech Connect

    Porter, V.L.

    1993-12-31

    One of the areas of current interest in the nuclear power industry is the response of containment buildings to internal pressures that may exceed design pressure levels. Evaluating the response of structures under these conditions requires computing beyond design load to the ultimate load of the containment. For concrete containments, this requirement means computing through severe concrete cracking and into the regime of wide-spread plastic rebar and/or tendon response. In this regime of material response, an implicit code can have trouble converging. This paper describes some of the author`s experiences with Version 5.2 of ABAQUS Standard and the ABAQUS concrete model in computing the axisymmetric response of a prestressed concrete containment to ultimate global structural failure under high internal pressures. The effects of varying the tension stiffening parameter in the concrete material model and variations of the parameters for the CONTROLS option are discussed.

  1. Do Environmental Conditions Contribute to Narcosis Onset and Symptom Severity?

    PubMed

    Lafère, P; Balestra, C; Hemelryck, W; Guerrero, F; Germonpré, P

    2016-12-01

    Although many factors contributing to inert gas narcosis onset and severity have been put forward, the available evidence is not particularly strong. Using objective criteria, we have assessed brain impairment associated with narcosis under various environmental diving conditions. 40 volunteers performed a no-decompression dive (33 m for 20 min) either in a dry chamber, a pool or open sea. They were assessed by critical flicker fusion frequency before the dive, upon arriving at depth, 5 min before ascent, on surfacing and 30 min post-dive. Compared to the pre-dive value, the mean value of each measurement was significantly different. An increase of flicker fusion to 105.00±0.69% when arriving at depth is followed by a decrease to 94.05±0.65%. This impairment persists when surfacing and 30 min post-dive, decreasing further to 96.36±0.73% and 96.24±0.73%, respectively. Intragroup comparison failed to demonstrate any statistical difference. When objectively measured narcosis may not be influenced by external factors other than pressure and gas. This might be of importance for training to avoid any over- or underestimation of the severity of narcosis based only on subjective symptoms.

  2. Cytoreductive conditioning for severe combined immunodeficiency--help or hindrance?

    PubMed

    Laberko, Alexandra; Gennery, Andrew R

    2015-01-01

    Use of chemotherapy-based conditioning-facilitated engraftment in patients with severe combined immunodeficiency (SCID) is contentious. In T- and NK lymphocyte-negative, B-lymphocyte-positive (T-B+NK+) and T-B-NK+ SCID, the osteo-medullary space is occupied by recipient hematopoietic stem cells and mature B-lymphocytes. The thymic niche is empty in T-B+NK+ SCID but fully occupied by developmentally arrested T-lymphocyte precursors in T-B-NK+ SCID. The outcome of infusion of donor stem cells differs and is dependent on genetic defect and the lymphocyte developmental arrest stage. At best, donor hematopoietic stem cell osteo-medullary engraftment induces normal B-lymphocyte function and long-term thymopoiesis; at worst, peripheral expansion of donor T-lymphocytes from the stem cell source results in a restricted T-lymphocyte receptor repertoire with possible B-lymphocyte failure. Conditioning improves immunoreconstitution but causes short- and long-term toxicities, and increased mortality. Newborn screening for SCID will propel the search for safe, effective methods of achieving donor cell engraftment and full immunoreconstitution without toxic sequalae.

  3. Experimental Study of the Rolling-Sliding Contact Conditions in a PA66/STEEL Gear Using Twin-Disc Test Rig: Friction and Wear Analysis

    NASA Astrophysics Data System (ADS)

    Mbarek, Meftah; Rhaiem, Sadok; Kharrat, Mohamed; Dammak, Maher

    2015-09-01

    This study investigates the effects of sliding ratio on the tribological response of the contact between the teeth of a metal/polymer gear in the regions close to the pitch point. For this purpose, a new twin-disc test rig was developed on the basis of two discs of different diameters rotating one above the other at the same angular speed. Two different materials were used: non-alloyed structural steel (C45) and polyamide (PA66). The effect of the slip ratio (4%, 12%, 20% and 28%) was studied at a constant pressure of 34 MPa and a constant angular speed of 300 rpm. In addition, the contact conditions were controlled with measurements of the two discs surface temperatures. The results indicate that the wear and the friction are closely related to the contact temperature generated by the sliding phenomenon. At low slip ratio (4% and 12%), the coefficient of friction and the temperature are characterized by a quasi-linear increase with time, and the wear increases slowly. At higher slip ratio (20% and 28%), the coefficient of friction and the temperature presents a steady state, and the wear increases dramatically. During the test, a film of transferred PA66 is formed on the steel surface causing the development of adhesive interactions between the contacting discs which increase the friction coefficient and the contact temperature. The high thermal conductivity of steel as compared to that of the polymer can reduce enormously the contact temperature generated by the sliding process.

  4. Failure to elicit conditioned taste aversion by severe poisoning.

    PubMed

    Ionescu, E; Buresová, O

    1977-03-01

    In an attempt to assess the universal validity of the conditioned taste aversion (CTA) paradigm, various types of poisoning (UC) were associated with the gustatory CS. Water deprived rats were habituated for two days to the drinking box, where water was available for 15 min. On Day 3, access to the CS (0.1% saccharin 15 min) was followed after 30 min by a sublethal dose of the poison (0.15 M LiCl, 4% body weight; 0.1 M sodium malonate, 1% body weight; pyrrolopyrimidine drug BW 58-271, 15 mg/kg; sodium cyanide 4 mg/kg; sodium iodoacetate 40 mg/kg; sodium fluoride 30 mg/kg; gallamine triethiodide 40 mg/kg). Rats injected with the last drug were maintained under artificial respiration until muscular paralysis disappeared. After 4 days of recovery, water deprivation schedule was resumed on Days 8 and 9. During the retention test on Day 10 saccharin consumption dropped by 60% in the LiCl poisoned rats, but not CTA developed in animals poisoned by pyrrolopyrimidine, gallamine, malonate and cyanide. CTA of intermediate intensity was evoked by iodoacetate and fluoride. The absence of CTA was not due to the amnesic effect of poisoning, since LiCl administration to NaCN poisoned rats produced CTA of usual intensity. It is concluded that CTA is not related to the overall severity of poisoning but rather to the effect of the poison on specific interoceptors.

  5. Maximum power point tracking algorithm based on sliding mode and fuzzy logic for photovoltaic sources under variable environmental conditions

    NASA Astrophysics Data System (ADS)

    Atik, L.; Petit, P.; Sawicki, J. P.; Ternifi, Z. T.; Bachir, G.; Della, M.; Aillerie, M.

    2017-02-01

    Solar panels have a nonlinear voltage-current characteristic, with a distinct maximum power point (MPP), which depends on the environmental factors, such as temperature and irradiation. In order to continuously harvest maximum power from the solar panels, they have to operate at their MPP despite the inevitable changes in the environment. Various methods for maximum power point tracking (MPPT) were developed and finally implemented in solar power electronic controllers to increase the efficiency in the electricity production originate from renewables. In this paper we compare using Matlab tools Simulink, two different MPP tracking methods, which are, fuzzy logic control (FL) and sliding mode control (SMC), considering their efficiency in solar energy production.

  6. Pain description and severity of chronic orofacial pain conditions.

    PubMed

    Vickers, E R; Cousins, M J; Woodhouse, A

    1998-12-01

    A multidisciplinary pain centre study of 120 consecutive chronic orofacial pain patients assessed pain description and intensity ratings, gender differences, prevalence of concurrent conditions, and interinstrument relationships of the McGill Pain Questionnaire and visual analogue scale. Pain words chosen by patients to describe conditions were predominantly sensory words, and patients with concurrent conditions often listed words indicating a substantial affective component. Results showed pain intensity ratings of chronic orofacial pain conditions have similar or higher pain ratings when compared with other medical chronic pain conditions such as back pain, cancer pain and arthritis. There was a significantly higher female: male ratio (88:32) with gender playing an important but poorly understood causal role. The most frequent condition diagnosed was atypical facial pain (n = 40), followed by temporomandibular disorder (n = 32), atypical odontalgia (n = 29) and pathology of the orofacial region (n = 19). Temporomandibular disorder was present in 75 of the 120 subjects, as the sole pain complaint (n = 32) or as an associated secondary condition (n = 43), indicating concurrent pain conditions exist and may be related. There were significantly higher total pain scores of the McGill Pain Questionnaire in patients with multiple conditions compared with patients with a single condition. The visual analogue scale showed a significant correlation to the number of words chosen index of the McGill Pain Questionnaire for orofacial pain.

  7. Offshore Wind Power Integration in severely fluctuating Wind Conditions

    NASA Astrophysics Data System (ADS)

    von Bremen, L.

    2010-09-01

    Strong power fluctuations from offshore wind farms that are induced by wind speed fluctuations pose a severe problem to the save integration of offshore wind power into the power supply system. Experience at the first large-scale offshore wind farm Horns Rev showed that spatial smoothing of power fluctuations within a single wind farm is significantly smaller than onshore results suggest when distributed wind farms of 160 MW altogether are connected to a single point of common-coupling. Wind power gradients larger than 10% of the rated capacity within 5 minutes require large amount of regulation power that is very expensive for the grid operator. It must be noted that a wind speed change of only 0.5m/s result in a wind power change of 10% (within the range of 9-11 m/s where the wind power curve is steepest). Hence, it is very important for the grid operator to know if strong fluctuations are likely or not. Observed weather conditions at the German wind energy research platform FINO1 in the German bight are used to quantify wind fluctuations. With a standard power curve these wind fluctuations are transfered to wind power. The aim is to predict the probability of exceedence of certain wind power gradients that occur in a time interval of e.g. 12 hours. During 2006 and 2009 the distribution of wind power fluctuations looks very similar giving hope that distinct atmospheric processes can be determined that act as a trigger. Most often high wind power fluctuations occur in a range of wind speeds between 9-12 m/s as can be expected from the shape of the wind power curve. A cluster analysis of the 500 hPa geopotential height to detect predominant weather regimes shows that high fluctuations are more likely in north-western flow. It is shown that most often high fluctuations occur in non-stable atmospheric stratification. The description of stratification by means of the vertical gradient of the virtual potential temperature is chosen to be indicative for convection, i

  8. Preignition Characteristics of Several Fuels Under Simulated Engine Conditions

    NASA Technical Reports Server (NTRS)

    Spencer, R C

    1941-01-01

    The preignition characteristics of a number of fuels have been studied under conditions similar to those encountered in an engine. These conditions were simulated by suddenly compressing a fuel-air mixture in contact with an electrically heated hot spot in the cylinder head of the NACA combustion apparatus. Schlieren photographs and indicator cards were taken of the burning, and the hot-spot temperatures necessary to cause ignition under various conditions were determined.

  9. Finite-time control of DC-DC buck converters via integral terminal sliding modes

    NASA Astrophysics Data System (ADS)

    Chiu, Chian-Song; Shen, Chih-Teng

    2012-05-01

    This article presents novel terminal sliding modes for finite-time output tracking control of DC-DC buck converters. Instead of using traditional singular terminal sliding mode, two integral terminal sliding modes are introduced for robust output voltage tracking of uncertain buck converters. Different from traditional sliding mode control (SMC), the proposed controller assures finite convergence time for the tracking error and integral tracking error. Furthermore, the singular problem in traditional terminal SMC is removed from this article. When considering worse modelling, adaptive integral terminal SMC is derived to guarantee finite-time convergence under more relaxed stability conditions. In addition, several experiments show better start-up performance and robustness.

  10. Effect of triangular texture on the tribological performance of die steel with TiN coatings under lubricated sliding condition

    NASA Astrophysics Data System (ADS)

    Chen, Ping; Xiang, Xin; Shao, Tianmin; La, Yingqian; Li, Junling

    2016-12-01

    The friction and wear of stamping die surface can affect the service life of stamping die and the quality of stamping products. Surface texturing and surface coating have been widely used to improve the tribological performance of mechanical components. This study experimentally investigated the effect of triangular surface texture on the friction and wear properties of the die steel substrate with TiN coatings under oil lubrication. TiN coatings were deposited on a die steel (50Cr) substrate through a multi-arc ion deposition system, and then triangular surface texturing was fabricated by a laser surface texturing. The friction and wear test was conducted by a UMT-3 pin-on-disk tribometer under different sliding speeds and different applied loads, respectively. The adhesion test was performed to evaluate the effectiveness of triangular texturing on the interfacial bonding strength between the TiN coating and the die steel substrate. Results show that the combination method of surface texturing process and surface coating process has excellent tribological properties (the lowest frictional coefficient and wear volume), compared with the single texturing process or the single coating process. The tribological performance is improved resulting from the high hardness and low elastic modulus of TiN coatings, and the generation of hydrodynamic pressure, function of micro-trap for wear debris and micro-reservoirs for lubricating oil of the triangular surface texture. In addition, the coating bonding strength of the texturing sample is 3.63 MPa, higher than that of the single coating sample (3.48 MPa), but the mechanisms remain to be further researched.

  11. Ceramic wear in indentation and sliding

    NASA Technical Reports Server (NTRS)

    Miyoshi, K.; Buckley, D. H.

    1984-01-01

    The various wear mechanisms involved with single-crystal ceramic materials in indentation and in sliding contacts. Experiments simulating interfacial events have been conducted with hemispherical, conical and pyramidal indenters (riders). With spherical riders, under either abrasive or adhesive conditions, two types of fracture pits have been observed. First, spherical-shaped fracture pits and wear particles are found as a result of either indenting or sliding. These are shown to be due to a spherical-shaped fracture along the circular or spherical stress trajectories. Second, polyhedral fracture pits and debris, produced by anisotropic fracture, and also found both during indenting and sliding. These are primarily controlled by surface and subsurface cracking along cleavage planes. Several quantitative results have also been obtained from this work. For example, using a pyramidal diamond, crack length of Mn-Zn ferrite in the indentation process grows linearly with increasing normal load. Moreover, the critical load to fracture both in indentation and sliding is essentially isotropic and is found to be directly proportional to the indenter radius.

  12. T-Slide Linear Actuators

    NASA Technical Reports Server (NTRS)

    Vranish, John

    2009-01-01

    T-slide linear actuators use gear bearing differential epicyclical transmissions (GBDETs) to directly drive a linear rack, which, in turn, performs the actuation. Conventional systems use a rotary power source in conjunction with a nut and screw to provide linear motion. Non-back-drive properties of GBDETs make the new actuator more direct and simpler. Versions of this approach will serve as a long-stroke, ultra-precision, position actuator for NASA science instruments, and as a rugged, linear actuator for NASA deployment duties. The T slide can operate effectively in the presence of side forces and torques. Versions of the actuator can perform ultra-precision positioning. A basic T-slide actuator is a long-stroke, rack-and-pinion linear actuator that, typically, consists of a T-slide, several idlers, a transmission to drive the slide (powered by an electric motor) and a housing that holds the entire assembly. The actuator is driven by gear action on its top surface, and is guided and constrained by gear-bearing idlers on its other two parallel surfaces. The geometry, implemented with gear-bearing technology, is particularly effective. An electronic motor operating through a GBDET can directly drive the T slide against large loads, as a rack and pinion linear actuator, with no break and no danger of back driving. The actuator drives the slide into position and stops. The slide holes position with power off and no brake, regardless of load. With the T slide configuration, this GBDET has an entire T-gear surface on which to operate. The GB idlers coupling the other two T slide parallel surfaces to their housing counterpart surfaces provide constraints in five degrees-of-freedom and rolling friction in the direction of actuation. Multiple GB idlers provide roller bearing strength sufficient to support efficient, rolling friction movement, even in the presence of large, resisting forces. T-slide actuators can be controlled using the combination of an off

  13. Cavity growth on a sliding grain boundary

    SciTech Connect

    I-Wei Chen

    1983-11-01

    Cavity growth on a sliding grain boundary to which a normal stress is applied is found to be faster than that on a stationary grain boundary. The morphology of the cavity contains an asymmetric crack-like tip which prompts surface diffusion locally when the sliding is dominant, and the growth rate becomes proportional to the third power of the normal stress independent of the sliding rate. Since the sliding rates of all grain boundaries are statistically comparable, only the normal stress dependence remains important. The conditions which favor the present mechanism are examined and shown to be in good agreement with the experimental evidence in creep cavitation.

  14. Sliding vane geometry turbines

    DOEpatents

    Sun, Harold Huimin; Zhang, Jizhong; Hu, Liangjun; Hanna, Dave R

    2014-12-30

    Various systems and methods are described for a variable geometry turbine. In one example, a turbine nozzle comprises a central axis and a nozzle vane. The nozzle vane includes a stationary vane and a sliding vane. The sliding vane is positioned to slide in a direction substantially tangent to an inner circumference of the turbine nozzle and in contact with the stationary vane.

  15. A Sliding Mode Control with Optimized Sliding Surface for Aircraft Pitch Axis Control System

    NASA Astrophysics Data System (ADS)

    Lee, Sangchul; Kim, Kwangjin; Kim, Youdan

    A sliding mode controller with an optimized sliding surface is proposed for an aircraft control system. The quadratic type of performance index for minimizing the angle of attack and the angular rate of the aircraft in the longitudinal motion is used to design the sliding surface. For optimization of the sliding surface, a Hamilton-Jacobi-Bellman (HJB) equation is formulated and it is solved through a numerical algorithm using a Generalized HJB (GHJB) equation and the Galerkin spectral method. The solution of this equation denotes a nonlinear sliding surface, on which the trajectory of the system approximately satisfies the optimality condition. Numerical simulation is performed for a nonlinear aircraft model with an optimized sliding surface and a simple linear sliding surface. The simulation result demonstrates that the proposed controller can be effectively applied to the longitudinal maneuver of an aircraft.

  16. Electrical equipment performance under severe accident conditions (BWR/Mark 1 plant analysis): Summary report

    SciTech Connect

    Bennett, P.R.; Kolaczkowski, A.M.; Medford, G.T.

    1986-09-01

    The purpose of the Performance Evaluation of Electrical Equipment during Severe Accident States Program is to determine the performance of electrical equipment, important to safety, under severe accident conditions. In FY85, a method was devised to identify important electrical equipment and the severe accident environments in which the equipment was likely to fail. This method was used to evaluate the equipment and severe accident environments for Browns Ferry Unit 1, a BWR/Mark I. Following this work, a test plan was written in FY86 to experimentally determine the performance of one selected component to two severe accident environments.

  17. Designing Good Slides. Revised.

    ERIC Educational Resources Information Center

    Center for Disease Control (DHEW/PHS), Atlanta, GA.

    This guide is designed to help those who want to illustrate material in a formal presentation using 35mm double-frame slides, and it is also useful as a guide for teaching students how to work with slides. The guide provides a step-by-step procedure for each format. For instance, those who want to design a slide with copy only would go through a…

  18. Experimental results from containment piping bellows subjected to severe accident conditions: Results from bellows tested in corroded conditions. Volume 2

    SciTech Connect

    Lambert, L.D.; Parks, M.B.

    1995-10-01

    Bellows are an integral part of the containment pressure boundary in nuclear power plants. They are used at piping penetrations to allow relative movement between piping and the containment wall, while minimizing the load imposed on the piping and wall. Piping bellows are primarily used in steel containments; however, they have received limited use in some concrete (reinforced and prestressed) containments. In a severe accident they may be subjected to pressure and temperature conditions that exceed the design values, along with a combination of axial and lateral deflections. A test program to determine the leak-tight capacity of containment penetration bellows is being conducted at Sandia National Laboratories under the sponsorship of the US Nuclear Regulatory Commission. Several different bellows geometries, representative of actual containment bellows, have been subjected to extreme deflections along with pressure and temperature loads. The bellows geometries and loading conditions are described along with the testing apparatus and procedures. A total of nineteen bellows have been tested. Thirteen bellows were tested in ``like-new`` condition (results reported in Volume 1), and six were tested in a corroded condition. The tests showed that bellows in ``like-new`` condition are capable of withstanding relatively large deformations, up to, or near, the point of full compression or elongation, before developing leakage, while those in a corroded condition did not perform as well, depending on the amount of corrosion. The corroded bellows test program and results are presented in this report.

  19. Fabrication and Wear Behavior Analysis on AlCrFeNi High Entropy Alloy Coating Under Dry Sliding and Oil Lubrication Test Conditions

    NASA Astrophysics Data System (ADS)

    Tang, Yipin; Wang, Shouren; Sun, Bin; Wang, Yan; Qiao, Yang

    2016-03-01

    In this paper, AlCrFeNi high entropy alloy coating was fabricated on the surface of Q235 steel using hot pressing sintering process. The coating has the controlled thickness size and excellent mechanical properties. Scanning electron microscopy (SEM), XRD and hardness testing method were used to study the morphology, phase structure and hardness of high entropy alloys coating. The lattice distortion plays a significant role in increasing the hardness. Coating formation mechanism caused by the element diffusion under the hot pressing effect is also discussed in the paper. Simultaneously, the dry sliding and oil lubrication wear tests, wear morphology observation and wear mechanism discussion were completed. As the result shows, AlCrFeNi high entropy alloys coating exhibits superior wear resistance either at dry sliding or oil lubrication tests owing to its hard high entropy solid solution structure.

  20. Key Parameters for Operator Diagnosis of BWR Plant Condition during a Severe Accident

    SciTech Connect

    Clayton, Dwight A.; Poore, III, Willis P.

    2015-01-01

    The objective of this research is to examine the key information needed from nuclear power plant instrumentation to guide severe accident management and mitigation for boiling water reactor (BWR) designs (specifically, a BWR/4-Mark I), estimate environmental conditions that the instrumentation will experience during a severe accident, and identify potential gaps in existing instrumentation that may require further research and development. This report notes the key parameters that instrumentation needs to measure to help operators respond to severe accidents. A follow-up report will assess severe accident environmental conditions as estimated by severe accident simulation model analysis for a specific US BWR/4-Mark I plant for those instrumentation systems considered most important for accident management purposes.

  1. Improving condition severity classification with an efficient active learning based framework.

    PubMed

    Nissim, Nir; Boland, Mary Regina; Tatonetti, Nicholas P; Elovici, Yuval; Hripcsak, George; Shahar, Yuval; Moskovitch, Robert

    2016-06-01

    Classification of condition severity can be useful for discriminating among sets of conditions or phenotypes, for example when prioritizing patient care or for other healthcare purposes. Electronic Health Records (EHRs) represent a rich source of labeled information that can be harnessed for severity classification. The labeling of EHRs is expensive and in many cases requires employing professionals with high level of expertise. In this study, we demonstrate the use of Active Learning (AL) techniques to decrease expert labeling efforts. We employ three AL methods and demonstrate their ability to reduce labeling efforts while effectively discriminating condition severity. We incorporate three AL methods into a new framework based on the original CAESAR (Classification Approach for Extracting Severity Automatically from Electronic Health Records) framework to create the Active Learning Enhancement framework (CAESAR-ALE). We applied CAESAR-ALE to a dataset containing 516 conditions of varying severity levels that were manually labeled by seven experts. Our dataset, called the "CAESAR dataset," was created from the medical records of 1.9 million patients treated at Columbia University Medical Center (CUMC). All three AL methods decreased labelers' efforts compared to the learning methods applied by the original CAESER framework in which the classifier was trained on the entire set of conditions; depending on the AL strategy used in the current study, the reduction ranged from 48% to 64% that can result in significant savings, both in time and money. As for the PPV (precision) measure, CAESAR-ALE achieved more than 13% absolute improvement in the predictive capabilities of the framework when classifying conditions as severe. These results demonstrate the potential of AL methods to decrease the labeling efforts of medical experts, while increasing accuracy given the same (or even a smaller) number of acquired conditions. We also demonstrated that the methods included in

  2. Herbaceous Ornamental Plants. Slide Script.

    ERIC Educational Resources Information Center

    Still, Steven

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with commercially important herbaceous ornamental plants. Included in the script are narrations for use with a total of 338 slides illustrating 150 different plants. Generally, two slides are used to illustrate each plant: one slide shows…

  3. Mailing microscope slides

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Many insects feed agriculturally important crops, trees, and ornamental plants and cause millions of dollars of damage annually. Identification for some of these require the preparation of a microscope slide for examination. There are times when a microscope slide may need to be sent away to a speci...

  4. A frictional sliding algorithm for liquid droplets

    NASA Astrophysics Data System (ADS)

    Sauer, Roger A.

    2016-12-01

    This work presents a new frictional sliding algorithm for liquid menisci in contact with solid substrates. In contrast to solid-solid contact, the liquid-solid contact behavior is governed by the contact line, where a contact angle forms and undergoes hysteresis. The new algorithm admits arbitrary meniscus shapes and arbitrary substrate roughness, heterogeneity and compliance. It is discussed and analyzed in the context of droplet contact, but it also applies to liquid films and solids with surface tension. The droplet is modeled as a stabilized membrane enclosing an incompressible medium. The contact formulation is considered rate-independent such that hydrostatic conditions apply. Three distinct contact algorithms are needed to describe the cases of frictionless surface contact, frictionless line contact and frictional line contact. For the latter, a predictor-corrector algorithm is proposed in order to enforce the contact conditions at the contact line and thus distinguish between the cases of advancing, pinning and receding. The algorithms are discretized within a monolithic finite element formulation. Several numerical examples are presented to illustrate the numerical and physical behavior of sliding droplets.

  5. Severe Pulmonary Toxicity After Myeloablative Conditioning Using Total Body Irradiation: An Assessment of Risk Factors

    SciTech Connect

    Kelsey, Chris R.; Horwitz, Mitchell E.; Chino, Junzo P.; Craciunescu, Oana; Steffey, Beverly; Folz, Rodney J.; Chao, Nelson J.; Rizzieri, David A.; Marks, Lawrence B.

    2011-11-01

    Purpose: To assess factors associated with severe pulmonary toxicity after myeloablative conditioning using total body irradiation (TBI) followed by allogeneic stem cell transplantation. Methods and Materials: A total of 101 adult patients who underwent TBI-based myeloablative conditioning for hematologic malignancies at Duke University between 1998 and 2008 were reviewed. TBI was combined with high-dose cyclophosphamide, melphalan, fludarabine, or etoposide, depending on the underlying disease. Acute pulmonary toxicity, occurring within 90 days of transplantation, was scored using Common Terminology Criteria for Adverse Events version 3.0. Actuarial overall survival and the cumulative incidence of acute pulmonary toxicity were calculated via the Kaplan-Meier method and compared using a log-rank test. A binary logistic regression analysis was performed to assess factors independently associated with acute severe pulmonary toxicity. Results: The 90-day actuarial risk of developing severe (Grade 3-5) pulmonary toxicity was 33%. Actuarial survival at 90 days was 49% in patients with severe pulmonary toxicity vs. 94% in patients without (p < 0.001). On multivariate analysis, the number of prior chemotherapy regimens was the only factor independently associated with development of severe pulmonary toxicity (odds ratio, 2.7 per regimen). Conclusions: Severe acute pulmonary toxicity is prevalent after TBI-based myeloablative conditioning regimens, occurring in approximately 33% of patients. The number of prior chemotherapy regimens appears to be an important risk factor.

  6. Shipping container response to severe highway and railway accident conditions: Main report

    SciTech Connect

    Fischer, L.E.; Chou, C.K.; Gerhard, M.A.; Kimura, C.Y.; Martin, R.W.; Mensing, R.W.; Mount, M.E.; Witte, M.C.

    1987-02-01

    This report describes a study performed by the Lawrence Livermore National Laboratory to evaluate the level of safety provided under severe accident conditions during the shipment of spent fuel from nuclear power reactors. The evaluation is performed using data from real accident histories and using representative truck and rail cask models that likely meet 10 CFR 71 regulations. The responses of the representative casks are calculated for structural and thermal loads generated by severe highway and railway accident conditions. The cask responses are compared with those responses calculated for the 10 CFR 71 hypothetical accident conditions. By comparing the responses it is determined that most highway and railway accident conditions fall within the 10 CFR 71 hypothetical accident conditions. For those accidents that have higher responses, the probabilities anf potential radiation exposures of the accidents are compared with those identified by the assessments made in the ''Final Environmental Statement on the Transportation of Radioactive Material by Air and other Modes,'' NUREG-0170. Based on this comparison, it is concluded that the radiological risks from spent fuel under severe highway and railway accident conditions as derived in this study are less than risks previously estimated in the NUREG-0170 document.

  7. Teaching an Individual with Severe Intellectual Delay to Request Assistance Conditionally

    ERIC Educational Resources Information Center

    Reichle, Joe; McComas, Jennifer; Dahl, Norm; Solberg, Gina; Pierce, Sarah; Smith, David

    2005-01-01

    The purpose of this study was to evaluate intervention procedures to teach conditional use of a communicative request for assistance and independent task performance. A 40-year-old man with autism and severe mental retardation with a history of escape-related problems was taught to use a graphic symbol to request assistance and to engage…

  8. Temperature histories of commercial flights at severe conditions from GASP data

    NASA Technical Reports Server (NTRS)

    Jasperson, W. H.; Nastrom, G. D.

    1983-01-01

    The thermal environment of commercial aircraft from a data set gathered during the Global Atmospheric Sampling Program (GASP) is studied. The data set covers a four-year period of measurements. The report presents plots of airplane location and speed and atmospheric temperature as functions of elapsed time for 35 extreme-condition flights, selected by minimum values of several temperature parameters. One of these parameters, the severity factor, is an approximation of the in-flight wing-tank temperature. Representative low-severity-factor flight histories may be useful for actual temperature-profile inputs to design and research studies. Comparison of the GASP atmospheric temperatures to interpolated temperatures from National Meteorological Center and Global Weather Central analysis fields shows that the analysis temperatures are slightly biased toward warmer than actual temperatures, particularly over oceans and at extreme conditions.

  9. Cryogenic Tunnel Pressure Measurements on a Supercritical Airfoil for Several Shock Buffet Conditions

    NASA Technical Reports Server (NTRS)

    Bartels, Robert E.; Edwards, John W.

    1997-01-01

    Steady and unsteady experimental data are presented for several fixed geometry conditions from a test in the NASA Langley 0.3-Meter Transonic Cryogenic Tunnel. The purpose of this test was to obtain unsteady data for transonic conditions on a fixed and pitching supercritical airfoil at high Reynolds numbers. Data and brief analyses for several of the fixed geometry test conditions will be presented here. These are at Reynolds numbers from 6 x 10(exp 6) to 35 x 10(exp 6) bases on chord length, and span a limited range of Mach numbers and angles of attack just below and at the onset of shock buffet. Reynolds scaling effects appear in both the steady pressure data and in the onset of shock buffet at Reynolds numbers of 15 x 10(exp 6) and 3O x 10(exp 6) per chord length.

  10. Biological control of bacterial speck of tomato under field conditions at several locations in north america.

    PubMed

    Wilson, M; Campbell, H L; Ji, P; Jones, J B; Cuppels, D A

    2002-12-01

    ABSTRACT Bacterial speck of tomato, caused by Pseudomonas syringae pv. tomato, continues to be a problem for tomato growers worldwide. A collection of nonpathogenic bacteria from tomato leaves plus P. syringae strains TLP2 and Cit7, P. fluorescens strain A506, and P. syringae pv. tomato DC3000 hrp mutants were examined in a greenhouse bioassay for the ability to reduce foliar bacterial speck disease severity. While several of these strains significantly reduced disease severity, P. syringae Cit7 was the most effective, providing a mean level of disease reduction of 78% under greenhouse conditions. The P. syringae pv. tomato DC3000 hrpA, hrpH, and hrpS mutants also significantly reduced speck severity under greenhouse conditions. The strains with the greatest efficacy under greenhouse conditions were tested for the ability to reduce bacterial speck under field conditions at locations in Alabama, Florida, and Ontario, Canada. P. syringae Cit7 was the most effective strain, providing a mean level of disease reduction of 28% over 10 different field experiments. P. fluorescens A506, which is commercially available as Blight-Ban A506, provided a mean level of disease reduction of 18% over nine different field experiments. While neither P. syringae Cit7 nor P. fluorescens A506 can be integrated with copper bactericides due to their copper sensitivity, there exist some potential for integrating these biological control agents with "plant activators", including Actigard. Of the P. syringae pv. tomato DC3000 hrp mutants tested, only the hrpS mutant reduced speck severity significantly under field conditions.

  11. 3D finite element modeling of sliding wear

    NASA Astrophysics Data System (ADS)

    Buentello Hernandez, Rodolfo G.

    Wear is defined as "the removal of material volume through some mechanical process between two surfaces". There are many mechanical situations that can induce wear and each can involve many wear mechanisms. This research focuses on the mechanical wear due to dry sliding between two surfaces. Currently there is a need to identify and compare materials that would endure sliding wear under severe conditions such as high velocities. The high costs associated with the field experimentation of systems subject to high-speed sliding, has prevented the collection of the necessary data required to fully characterize this phenomena. Simulating wear through Finite Elements (FE) would enable its prediction under different scenarios and would reduce experimentation costs. In the aerospace, automotive and weapon industries such a model can aid in material selection, design and/or testing of systems subjected to wear in bearings, gears, brakes, gun barrels, slippers, locomotive wheels, or even rocket test tracks. The 3D wear model presented in this dissertation allows one to reasonably predict high-speed sliding mechanical wear between two materials. The model predictions are reasonable, when compared against those measured on a sled slipper traveling over the Holloman High Speed Tests Track. This slipper traveled a distance of 5,816 meters in 8.14 seconds and reached a maximum velocity of 1,530 m/s.

  12. Design for slides.

    PubMed

    Johns, M

    1995-09-01

    The basic principles of design for projection slides are discussed, with particular reference to the impact of the personal computer and commercial presentation software on the material that is destined to end up on the screen at meetings and in seminar rooms. While modern software can be a boon to the presenter, allowing simple creation of slides, it can also encourage some of the worst excesses. The keynote of the design of slides for educational purposes should be simplicity, and ways of achieving simple but effective results are described.

  13. The effects of road-surface conditions, age, and gender on driver-injury severities.

    PubMed

    Morgan, Abigail; Mannering, Fred L

    2011-09-01

    Drivers' adaptation to weather-induced changes in roadway-surface conditions is a complex process that can potentially be influenced by many factors including age and gender. Using a mixed logit analysis, this research assesses the effects that age, gender, and other factors have on crash severities by considering single-vehicle crashes that occurred on dry, wet, and snow/ice-covered roadway surfaces. With an extensive database of single-vehicle crashes from Indiana in 2007 and 2008, estimation results showed that there were substantial differences across age/gender groups under different roadway-surface conditions. For example, for all females and older males, the likelihood of severe injuries increased when crashes occurred on wet or snow/ice surfaces-but for male drivers under 45 years of age, the probability of severe injuries decreased on wet and snow/ice surfaces - relative to dry-surface crashes. This and many other significant differences among age and gender groups suggest that drivers perceive and react to pavement-surface conditions in very different ways, and this has important safety implications. Furthermore, the empirical findings of this study highlight the value of considering subsets of data to unravel the complex relationships within crash-injury severity analysis.

  14. Study of light water reactor containments under important severe accident conditions

    SciTech Connect

    Hofmayer, C.H.; Pratt, W.T.; Bagchi, G.; Noonan, V.S.

    1985-01-01

    The US Nuclear Regulatory Commission has sponsored studies to develop a ''LEAKAGE-BEFORE-FAILURE'' model for use in severe accident risk assessments to provide a means of accounting for significant containment leakage prior to reaching the containment threshold pressure. Six containment types have been studied (large dry, subatmospheric, ice condenser, Mark I, II, and III). Potential leak paths through major containment penetration assemblies were investigated and upper-bound estimates of leak areas established. These leak areas may result from increasing internal pressure and degradation of nonmetallic seal materials due to severe accident conditions. This paper describes the approach and summarizes the results and conclusions of this study.

  15. Estimate of radionuclide release characteristics into containment under severe accident conditions. Final report

    SciTech Connect

    Nourbakhsh, H.P.

    1993-11-01

    A detailed review of the available light water reactor source term information is presented as a technical basis for development of updated source terms into the containment under severe accident conditions. Simplified estimates of radionuclide release and transport characteristics are specified for each unique combination of the reactor coolant and containment system combinations. A quantitative uncertainty analysis in the release to the containment using NUREG-1150 methodology is also presented.

  16. A Comparison of Perturbed Initial Conditions and Multiphysics Ensembles in a Severe Weather Episode in Spain

    NASA Technical Reports Server (NTRS)

    Tapiador, Francisco; Tao, Wei-Kuo; Angelis, Carlos F.; Martinez, Miguel A.; Cecilia Marcos; Antonio Rodriguez; Hou, Arthur; Jong Shi, Jain

    2012-01-01

    Ensembles of numerical model forecasts are of interest to operational early warning forecasters as the spread of the ensemble provides an indication of the uncertainty of the alerts, and the mean value is deemed to outperform the forecasts of the individual models. This paper explores two ensembles on a severe weather episode in Spain, aiming to ascertain the relative usefulness of each one. One ensemble uses sensible choices of physical parameterizations (precipitation microphysics, land surface physics, and cumulus physics) while the other follows a perturbed initial conditions approach. The results show that, depending on the parameterizations, large differences can be expected in terms of storm location, spatial structure of the precipitation field, and rain intensity. It is also found that the spread of the perturbed initial conditions ensemble is smaller than the dispersion due to physical parameterizations. This confirms that in severe weather situations operational forecasts should address moist physics deficiencies to realize the full benefits of the ensemble approach, in addition to optimizing initial conditions. The results also provide insights into differences in simulations arising from ensembles of weather models using several combinations of different physical parameterizations.

  17. Affective responses of high and low body satisfied men to viewing physique slides.

    PubMed

    Hausenblas, Heather A; Janelle, Christopher M; Gardner, Rebecca Ellis; Hagan, Amy L

    2003-01-01

    The purpose of this study was to examine the acute affective responses of high and low body satisfied (BS) men who viewed physique slides of the male ideal (model-slides), physique slides of themselves (self-slides), and nonphysique slides (control-slides). During three laboratory visits the participants viewed the slides from one of the three conditions, and they completed pre-, in-, and post-task affective measures. It was found that the: (a) high BS group reported less mood disturbance than the low BS group; (b) participants reported an increase in depression, anger, and body dissatisfaction after viewing the self-slides; (c) participants indicated a decrease in body dissatisfaction after viewing the model-slides; and (d) viewing the control-slides did not result in affective changes. Findings suggest that viewing physique slides results in increased mood disturbance, regardless of BS level.

  18. Quasistatic manipulation with compliance and sliding

    SciTech Connect

    Kao, I. ); Cutkosky, M.R. )

    1992-02-01

    The authors propose a method for modeling dextrous manipulation with sliding fingers. The approach combines compliance and friction limit surfaces. The method is useful for describing how a grasp will behave in the presence of external forces (e.g., when and how the fingertips will slide) and for planning how to control the fingers so that the grasped object will follow a desired trajectory. The sliding trajectories are characterized by a transient and steady-state solution. The underlying theory is first discussed and illustrated with several single-finger examples. Experimental results are also presented. The analysis is then extended to grasps with multiple sliding and nonsliding fingers. The multifinger analysis is illustrated with an example of manipulating a card with two soft-contact fingers.

  19. Fundamentals of the Slide Library.

    ERIC Educational Resources Information Center

    Boerner, Susan Zee

    This paper is an introduction to the fundamentals of the art (including architecture) slide library, with some emphasis on basic procedures of the science slide library. Information in this paper is particularly relevant to the college, university, and museum slide library. Topics addressed include: (1) history of the slide library; (2) duties of…

  20. Ornamental Landscape Grasses. Slide Script.

    ERIC Educational Resources Information Center

    Still, Steven M.; Adams, Denise W.

    This slide script to accompany the slide series, Ornamental Landscape Grasses, contains photographs of the 167 slides and accompanying narrative text intended for use in the study and identification of commercially important ornamental grasses and grasslike plants. Narrative text is provided for slides of 62 different perennial and annual species…

  1. The Effect of Sliding Speed on Film Thickness and Pressure Supporting Ability of a Point Contact Under Zero Entrainment Velocity Conditions

    NASA Technical Reports Server (NTRS)

    Thompson, Peter M.; Jones, William R., Jr.; Jansen, Mark J.; Prahl, Joseph M.

    2000-01-01

    A unique tribometer is used to study film forming and pressure supporting abilities of point contacts at zero entrainment velocity (ZEV). Film thickness is determined using a capacitance technique, verified through comparisons of experimental results and theoretical elastohydrodynamic lubrication (EHL) predictions for rolling contacts. Experiments are conducted using through hardened AISI 52 100 steel balls, Polyalphaolefin (PAO) 182 and Pentaerythritol Tetraheptanoate (PT) lubricants, and sliding speeds between 2.0 to 12.0 m/s. PAO 182 and PT are found to support pressures up to 1. 1 GPa and 0.67 GPa respectively. Protective lubricant films ranging in thickness between 90 to 2 10 nm for PAO 182 and 220 to 340 nm for PT are formed. Lubricants experience shear stresses between 14 to 22 MPa for PAO 182 and 7 to 16 MPa for PT at shear rates of 10(exp 7)/sec. The lubricant's pressure supporting ability most likely results from the combination of immobile films and its transition to a glassy solid at high pressures.

  2. Predictions of structural integrity of steam generator tubes under normal operating, accident, and severe accident conditions

    SciTech Connect

    Majumdar, S.

    1996-09-01

    Available models for predicting failure of flawed and unflawed steam generator tubes under normal operating, accident, and severe accident conditions are reviewed. Tests conducted in the past, though limited, tended to show that the earlier flow-stress model for part-through-wall axial cracks overestimated the damaging influence of deep cracks. This observation is confirmed by further tests at high temperatures as well as by finite element analysis. A modified correlation for deep cracks can correct this shortcoming of the model. Recent tests have shown that lateral restraint can significantly increase the failure pressure of tubes with unsymmetrical circumferential cracks. This observation is confirmed by finite element analysis. The rate-independent flow stress models that are successful at low temperatures cannot predict the rate sensitive failure behavior of steam generator tubes at high temperatures. Therefore, a creep rupture model for predicting failure is developed and validated by tests under varying temperature and pressure loading expected during severe accidents.

  3. Hydrogen-control systems for severe LWR accident conditions - a state-of-technology report

    SciTech Connect

    Hilliard, R K; Postma, A K; Jeppson, D W

    1983-03-01

    This report reviews the current state of technology regarding hydrogen safety issues in light water reactor plants. Topics considered in this report relate to control systems and include combustion prevention, controlled combustion, minimization of combustion effects, combination of control concepts, and post-accident disposal. A companion report addresses hydrogen generation, distribution, and combustion. The objectives of the study were to identify the key safety issues related to hydrogen produced under severe accident conditions, to describe the state of technology for each issue, and to point out ongoing programs aimed at resolving the open issues.

  4. Pre-Convective Environmental Conditions Indicative of Non-Tornadic Severe Thunderstorm Winds over Southeast Florida.

    DTIC Science & Technology

    1987-05-01

    EhEEEEEEEEMhhE mMhhEEEEEMhhhE [EOMOEEE L 6 II125 Am Vl P)COPY RESOI UTION TEST CHART DIlCEiIE COPY PRE-CONVECTIVE ENVIRONMENTAL CONDITIONS INDICATIVE...twelve dates selected by the initial model had reports of severe thunderstorm activity, but independent testing using data from May through September...implications for hail suppression. Quart. J. Roy. Meteor. Soc., 102, 499-533. Burpee , R.W., 1979: Peninsula-scale convergence in the south Florida

  5. Sensorimotor Difficulties Are Associated with the Severity of Autism Spectrum Conditions

    PubMed Central

    Hannant, Penelope; Cassidy, Sarah; Tavassoli, Teresa; Mann, Francesca

    2016-01-01

    Present diagnostic criteria for autism spectrum conditions (ASC) include social communication and interaction difficulties, repetitive behavior and movement, and atypical sensory responsivity. Few studies have explored the influence of motor coordination and sensory responsivity on severity of ASC symptoms. In the current study, we explore whether sensory responsivity and motor coordination differences can account for the severity of autistic behaviors in children with ASC. Thirty-six children participated: 18 (13 male, 5 female) with ASC (ages 7–16: mean age = 9.93 years) and 18 (7 male, 11 female) typically developing (TD) children (ages 6–12; mean age = 9.16 years). Both groups completed a battery of assessments that included motor coordination, sensory responsivity, receptive language, non-verbal reasoning and social communication measures. Children with ASC also completed the Autism Diagnostic Observation Schedule (ADOS) and Autism Diagnostic Interview—Revised (ADI-R). Results showed that children with ASC scored significantly lower on receptive language, coordination, sensory responsivity and a sensorimotor subscale, Modulation of Activity (MoA) compared to the TD group. In the ASC group, MoA significantly predicted ASC severity across all ASC measures; receptive language and sensory responsivity significantly predicted parental reported autism measures; and coordination significantly predicted examiner observed reported scores. Additionally, specific associations were found between the somatosensory perceptive modalities and ASC severity. The results show that sensorimotor skills are associated with severity of ASC symptoms; furthering the need to research sensorimotor integration in ASC and also implying that diagnosis of ASC should also include the assessment of both coordination deficit and atypical sensory responsivity. PMID:27582694

  6. Evolution of the sensor fish device for measuring physical conditions in sever hydraulic environments

    SciTech Connect

    Carlson, Thomas J.; Duncan, J. P.

    2003-03-01

    To assist in deriving biological specifications for design of turbine rehabilitation measures, new “fish-friendly” turbines, and spillway designs and operations, Pacific Northwest National Laboratory (PNNL) scientists have developed and tested an autonomous multi-sensor device called a Sensor Fish that can acquire pressure and tri-axial linear acceleration data during passage through severe hydraulic conditions. The purpose of the Sensor Fish is to characterize physical conditions fish experience during passage through hydro turbines, spill stilling basins, high-discharge outfalls, and other dam passage routes. This report discusses the development and field tests of the Sensor Fish at Rock Island, McNary, The Dalles, Bonneville, and Wanapum dams on the Columbia River and the Prosser Irrigation District on the Yakima River, which have shown that the device can withstand the severe environments of turbine, spill, and fish bypass passage and provide useful environmental data that can ultimately aid in the design and operation of new and existing turbines, spill, and dam fish bypass facilities.

  7. Evolution of the Sensor Fish Device for Measuring Physical Conditions in Severe Hydraulic Environments

    SciTech Connect

    Carlson, Thomas J.; Duncan, Joanne P.

    2003-02-28

    To assist in deriving biological specifications for design of turbine rehabilitation measures, new ''fish-friendly'' turbines, and spillway designs and operations, scientists at the Pacific Northwest National Laboratory (PNNL) have developed and tested an autonomous multi-sensor device called a Sensor Fish that can acquire pressure and tri-axial linear acceleration data during passage through severe hydraulic conditions. The purpose of the Sensor Fish is to characterize physical conditions fish experience during passage through hydro turbines, spill stilling basins, high-discharge outfalls, and other dam passage routes. The Sensor Fish was developed with the support of the U.S. Department of Energy's Advanced Hydropower Turbine System program. Field tests of the Sensor Fish at Rock Island, McNary, The Dalles, Bonneville, and Wanapum dams on the Columbia River and the Prosser Irrigation District on the Yakima River have shown that the device can withstand the severe environments of turbine, spill, and fish bypass passage and provide useful environmental data that can ultimately aid in the design and operation of new and existing turbines, spill, and dam fish bypass facilities.

  8. Slowing the Summer Slide

    ERIC Educational Resources Information Center

    Smith, Lorna

    2012-01-01

    Research shows that summer slide--the loss of learning over the summer break--is a huge contributor to the achievement gap between low-income students and their higher-income peers. In fact, some researchers have concluded that two-thirds of the 9th-grade reading achievement gap can be explained by unequal access to summer learning opportunities…

  9. Black and White Slides.

    ERIC Educational Resources Information Center

    Tanner, Jackie

    1979-01-01

    Outlines procedures for using some photographic techniques to start a black and white slide collection. Instructions are given for: (1) necessary equipment and materials; (2) photographing images such as photos, charts or drawings; (3) developing the film; and (4) setting up the filing system. Photographs and drawings illustrate the process. (AMH)

  10. On the Importance of Pickup Ion Precipitation to the Martian Thermosphere Under Severe Solar Wind Conditions

    NASA Astrophysics Data System (ADS)

    Fang, X.; Bougher, S. W.; Johnson, R. E.; Luhmann, J. G.; Liemohn, M. W.; Ma, Y.

    2012-12-01

    decreased Jeans parameter, we will also evaluate the importance of pickup ion precipitation in influencing the escape of neutral heavy species when the upstream solar wind conditions are severe.

  11. Hyperactivity induced by prenatal BrdU exposure across several experimental conditions.

    PubMed

    Kuwagata, Makiko; Ogawa, Tetsuo; Muneoka, Katsumasa; Shioda, Seiji

    2011-12-01

    Behavioral results are sometimes not reproducible even in the positive controls of developmental neurotoxicity (DNT) tests. Effects of several factors on the results should be considered. In the present paper, we examined the effects of strain-, gender-, and test-condition differences on BrdU-induced hyperactivity. The results showed that BrdU-induced hyperactivity was reproducible in two rat strains (SD and F344 rats), rodent species (rat and mouse), and both sexes. When the level of background sound in a test room was increased, the hyperactivity was persistent, resulting in no effect of background sound on BrdU-induced hyperactivity. Thus, we have demonstrated that the BrdU-animal model is a useful positive control via prenatal exposure to validate the entire DNT test process.

  12. Influence of normal loads and sliding velocities on friction properties of engineering plastics sliding against rough counterfaces

    NASA Astrophysics Data System (ADS)

    Nuruzzaman, D. M.; Chowdhury, M. A.; Rahaman, M. L.; Oumer, A. N.

    2016-02-01

    Friction properties of plastic materials are very important under dry sliding contact conditions for bearing applications. In the present research, friction properties of engineering plastics such as polytetrafluoroethylene (PTFE) and nylon are investigated under dry sliding contact conditions. In the experiments, PTFE and nylon slide against different rough counterfaces such as mild steel and stainless steel 316 (SS 316). Frictional tests are carried out at low loads 5, 7.5 and 10 N, low sliding velocities 0.5, 0.75 and 1 m/s and relative humidity 70%. The obtained results reveal that friction coefficient of PTFE increases with the increase in normal loads and sliding velocities within the observed range. On the other hand, frictional values of nylon decrease with the increase in normal loads and sliding velocities. It is observed that in general, these polymers show higher frictional values when sliding against SS 316 rather than mild steel. During running-in process, friction coefficient of PTFE and nylon steadily increases with the increase in rubbing time and after certain duration of rubbing, it remains at steady level. At identical operating conditions, the frictional values are significantly different depending on normal load, sliding velocity and material pair. It is also observed that in general, the influence of normal load on the friction properties of PTFE and nylon is greater than that of sliding velocity.

  13. Rhizobium-Legume Symbiosis and Nitrogen Fixation under Severe Conditions and in an Arid Climate

    PubMed Central

    Zahran, Hamdi Hussein

    1999-01-01

    Biological N2 fixation represents the major source of N input in agricultural soils including those in arid regions. The major N2-fixing systems are the symbiotic systems, which can play a significant role in improving the fertility and productivity of low-N soils. The Rhizobium-legume symbioses have received most attention and have been examined extensively. The behavior of some N2-fixing systems under severe environmental conditions such as salt stress, drought stress, acidity, alkalinity, nutrient deficiency, fertilizers, heavy metals, and pesticides is reviewed. These major stress factors suppress the growth and symbiotic characteristics of most rhizobia; however, several strains, distributed among various species of rhizobia, are tolerant to stress effects. Some strains of rhizobia form effective (N2-fixing) symbioses with their host legumes under salt, heat, and acid stresses, and can sometimes do so under the effect of heavy metals. Reclamation and improvement of the fertility of arid lands by application of organic (manure and sewage sludge) and inorganic (synthetic) fertilizers are expensive and can be a source of pollution. The Rhizobium-legume (herb or tree) symbiosis is suggested to be the ideal solution to the improvement of soil fertility and the rehabilitation of arid lands and is an important direction for future research. PMID:10585971

  14. Potential for containment leak paths through electrical penetration assemblies under severe accident conditions. [PWR; BWR

    SciTech Connect

    Sebrell, W.

    1983-07-01

    The leakage behavior of containments beyond design conditions and knowledge of failure modes is required for evaluation of mitigation strategies for severe accidents, risk studies, emergency preparedness planning, and siting. These studies are directed towards assessing the risk and consequences of severe accidents. An accident sequence analysis conducted on a Boiling Water Reactor (BWR), Mark I (MK I), indicated very high temperatures in the dry-well region, which is the location of the majority of electrical penetration assemblies. Because of the high temperatures, it was postulated in the ORNL study that the sealants would fail and all the electrical penetration assemblies would leak before structural failure would occur. Since other containments had similar electrical penetration assemblies, it was concluded that all containments would experience the same type of failure. The results of this study, however, show that this conclusion does not hold for PWRs because in the worst accident sequence, the long time containment gases stabilize to 350/sup 0/F. BWRs, on the other hand, do experience high dry-well temperatures and have a higher potential for leakage.

  15. Evaluation of oral tilmicosin efficacy against severe cryptosporidiosis in neonatal kids under field conditions.

    PubMed

    Paraud, C; Pors, I; Chartier, C

    2010-05-28

    Many compounds have been screened for their potential anti-cryptosporidial activity in ruminants but none of them has been totally efficient in controlling the disease. Macrolide antibiotics have demonstrated some activity against Cryptosporidium spp. in humans. Tilmicosin is a macrolide antibiotic, available in France in an oral form (Pulmotil AC, Lilly France). The preventive efficacy of tilmicosin was evaluated in a goat farm experiencing severe clinical cryptosporidiosis in kids. Twenty-two kids were separated from their dams just after birth and placed in a separated pen. They were divided into 3 groups: an untreated group (10 kids), group 1 (6 kids) receiving tilmicosin at 25mg/kg BW/day and group 2 (6 kids) receiving tilmicosin at 50mg/kg BW/day. Tilmicosin was individually given by oral route from day 2 of age for 10 days. Three times a week, individual faecal samples were performed to assess the oocyst output. Clinical data, i.e. diarrhea and mortality, were recorded. In control kids, the highest prevalence and intensity of excretion were observed between day 6 and day 16 of age and mortality reached 90%. Excretion dynamic and clinical consequences were similar in both treated kid groups. Finally, tilmicosin did not demonstrate any activity against severe kid cryptosporidiosis in field conditions.

  16. Containment performance of prototypical reactor containments subjected to severe accident conditions

    SciTech Connect

    Klamerus, E.W.; Bohn, M.P.; Wesley, D.A.; Krishnaswamy, C.N.

    1996-12-01

    In SECY-90-016, the NTRC proposed a safety goal of a conditional containment failure probability (CCFP) of 0.1 and the alternative acceptance criteria allowed for steel containments, which specifies that the stresses should not exceed ASNE Level C allowables for severe accident pressures and temperatures. In this work, the need for an equivalent criterion for concrete containments was studied. Six surrogate containments were designed and analyzed in order to compare the margins between design pressure, pressure resulting in exceedance of Level C (or yield) stress limits, and ultimate pressure. For comparability, each containment has an identical internal volume and design pressure. Results from the analysis showed margins to yield are comparable and display a similar margin for both steel and concrete containments. In addition, the margin to failure, although slightly higher in the steel containments, were also comparable. Finally, a CCFP for code design was determined based on general membrane behavior and imposing an upper bound severe accident curve developed in the DCH studies. The resulting CCFP`s were less then 0.02 (or 2%) for all the surrogate containments studied, showing that these containment designs all achieved the NRC safety goal.

  17. Predictions of structural integrity of steam generator tubes under normal operating, accident, an severe accident conditions

    SciTech Connect

    Majumdar, S.

    1997-02-01

    Available models for predicting failure of flawed and unflawed steam generator tubes under normal operating, accident, and severe accident conditions are reviewed. Tests conducted in the past, though limited, tended to show that the earlier flow-stress model for part-through-wall axial cracks overestimated the damaging influence of deep cracks. This observation was confirmed by further tests at high temperatures, as well as by finite-element analysis. A modified correlation for deep cracks can correct this shortcoming of the model. Recent tests have shown that lateral restraint can significantly increase the failure pressure of tubes with unsymmetrical circumferential cracks. This observation was confirmed by finite-element analysis. The rate-independent flow stress models that are successful at low temperatures cannot predict the rate-sensitive failure behavior of steam generator tubes at high temperatures. Therefore, a creep rupture model for predicting failure was developed and validated by tests under various temperature and pressure loadings that can occur during postulated severe accidents.

  18. Contriving transitive conditioned establishing operations to establish derived manding skills in adults with severe developmental disabilities.

    PubMed

    Rosales, Rocio; Rehfeldt, Ruth Anne

    2007-01-01

    The purpose of this study was to demonstrate derived manding skills in 2 adults with severe developmental disabilities and language deficits by contriving transitive conditioned establishing operations. Specifically, we evaluated whether a history of reinforced conditional discrimination learning would ultimately result in a derived mand repertoire, in which participants manded for items that were needed to complete chained tasks. After mastering the first three phases of the picture exchange communication system (PECS), participants were taught to mand for the needed items by exchanging pictures of the items for the items themselves. They were then taught to conditionally relate the dictated names of the items to the corresponding pictures of the items and to relate the dictated names to the corresponding printed words. We then tested, in the absence of reinforcement, whether participants would mand for the items needed to complete the chained tasks using text rather than pictures. Both participants showed the emergence of derived mands and some derived stimulus relations as a result of this instruction. Some of the derived relations were shown to be intact at 1-month follow-up, and scores on derived mand probes were higher at follow-up than before training. In addition, the 2 participants vocally requested the needed items on maintenance test probes, a skill that was never trained and was not previously in their repertoires. These results suggest that a history of reinforced relational responding may facilitate the expansion of a number of verbal skills and emphasize the possibility of a synthesis of Skinner's (1957) analysis of verbal behavior and derived stimulus relations into language-training efforts for persons with significant disabilities.

  19. Underwater Sliding Properties: Effect of Slider Shape and Surface Wettability

    NASA Astrophysics Data System (ADS)

    Kirveslahti, A.; Mielonen, K.; Ikonen, K.; Cui, W.; Suvanto, M.; Pakkanen, T. A.

    2016-04-01

    A dynamic test method for the measurement of the underwater sliding properties of model boats has been developed. Surface-modified model boats were examined to assess how the surface wettability properties affect sliding. Along with the surface properties, the influence of the boat shape was considered. We studied various coatings in the contact angle range of 3-162∘ with two model boat shapes. The hydrophobicity of the surfaces influenced the sliding speed of the model boat depending on the boat shape. The method is applicable to study sliding properties of model boats with different surfaces in variable flow conditions.

  20. Preparing Slide Presentations on Computers.

    ERIC Educational Resources Information Center

    Elberfeld, John K.

    1982-01-01

    Suggest use of well-organized slide presentation as effective way to introduce computers to large audiences and discusses how to get started--state objective, analyze audience, outline presentation, prepare slides--and equipment needed to obtain slides from television screens, miniature components, and book illustrations. References and sources…

  1. Sliding Luttinger liquid phases

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, Ranjan; Kane, C. L.; Lubensky, T. C.

    2001-07-01

    We study systems of coupled spin-gapped and gapless Luttinger liquids. First, we establish the existence of a sliding Luttinger liquid phase for a system of weakly coupled parallel quantum wires, with and without disorder. It is shown that the coupling can stabilize a Luttinger liquid phase in the presence of disorder. We then extend our analysis to a system of crossed Luttinger liquids and establish the stability of a non-Fermi-liquid state: the crossed sliding Luttinger liquid phase. In this phase the system exhibits a finite-temperature, long-wavelength, isotropic electric conductivity that diverges as a power law in temperature T as T-->0. This two-dimensional system has many properties of a true isotropic Luttinger liquid, though at zero temperature it becomes anisotropic. An extension of this model to a three-dimensional stack exhibits a much higher in-plane conductivity than the conductivity in a perpendicular direction.

  2. Reducing slide sheet injury.

    PubMed

    Varcin-Coad, Lynn

    2008-12-01

    Slide sheets are often stated to be the cause of hand and forearm injuries. While there are many other possible reasons injuries to nursing staff, carer and client occur, the most important linking factors relating to musculoskeletal disorders and manual handling of people is the ongoing inappropriateness or lack of suitably designed and equipped work areas. As physiotherapist Lynn Varcin-Coad writes, staff are bearing the brunt of inefficiencies of design and lack of high order risk control.

  3. Slide system for machine tools

    DOEpatents

    Douglass, Spivey S.; Green, Walter L.

    1982-01-01

    The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

  4. Slide system for machine tools

    DOEpatents

    Douglass, S.S.; Green, W.L.

    1980-06-12

    The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

  5. Novel catalytic materials for carbon dioxide reforming of methane under severely deactivating conditions

    NASA Astrophysics Data System (ADS)

    Stagg-Williams, Susan Michelle

    In recent years, the utilization of carbon dioxide for the reforming of methane (dry reforming) has attracted significant interest due to the industrial advantages over conventional steam reforming. The major obstacle preventing commercialization of this process is the lack of a catalyst capable of operating at the high temperatures and pressures required by industry. This thesis reports the study of the dry reforming reaction over SiO 2 and ZrO2 supported Pt catalysts. It was found that the Pt/ZrO2 catalyst had much higher activity and stability than the Pt/SiO2 catalyst due to the ability of the ZrO2 to adsorb CO2 near the metal particle, facilitating its dissociation. The decomposition of CH4 and the dissociation of CO2 occur via two independent pathways. CH4 decomposition occurs on the metal particle resulting in the formation of H2 and carbon deposition. When Pt is supported on ZrO2, the carbon formed during the decomposition of CH4 can reduce the support to form CO2 creating oxygen vacancies in the support lattice near the metal particle. The adsorption and dissociation of CO2 occurs at the vacancies, forming CO and replenishing the oxygen in the support lattice. This redox mechanism results in a cleaning of the metal particle by oxygen provided by the support. Promoters were added to both the metallic phase and to the support to improve the stability of the catalyst by decreasing carbon deposition. The co-impregnation of Sn and Pt on the ZrO2 resulted in lower activity and stability than the monometallic catalysts. Under oxidizing conditions, segregation of the Pt-Sn alloys occurred, resulting in the formation of tin oxide inhibiting the role of the ZrO2. Catalysts prepared by methods that allow for the controlled placement of Sn on the Pt particle, exhibited high activity and stability under severely deactivating conditions. Promotion of the ZrO2 support with cerium and lanthanum resulted in increased activity and stability of the catalyst. The improved

  6. Thermochemistry of Ruthenium Oxyhydroxide Species and Their Impact on Volatile Speciations in Severe Nuclear Accident Conditions.

    PubMed

    Miradji, Faoulat; Virot, François; Souvi, Sidi; Cantrel, Laurent; Louis, Florent; Vallet, Valérie

    2016-02-04

    Literature thermodynamic data of ruthenium oxyhydroxides reveal large uncertainties in some of the standard enthalpies of formation, motivating the use of high-level relativistic correlated quantum chemical methods to reduce the level of discrepancies. Reaction energies leading to the formation of all possible oxyhydroxide species RuOx(OH)y(H2O)z have been calculated for a series of reactions combining DFT (TPSSh-5%HF) geometries and partition functions, CCSD(T) energies extrapolated to the complete basis set limits. The highly accurate ab initio thermodynamic data were used as input data of thermodynamic equilibrium computations to derive the speciation of gaseous ruthenium species in the temperature, pressure and concentration conditions of severe nuclear accidents occurring in pressurized water reactors. At temperatures lower than 1000 K, gaseous ruthenium tetraoxide is the dominating species, between 1000 and 2000 K ruthenium trioxide becomes preponderant, whereas at higher temperatures gaseous ruthenium oxide, dioxide and even Ru in gaseous phase are formed. Although earlier studies predicted the formation of oxyhydroxides in significant quantities, the use of highly accurate ab initio thermodynamic data for ruthenium gaseous species leads to a more reliable inventory of gaseous ruthenium species in which gaseous oxyhydroxide ruthenium molecules are formed only in negligible amounts.

  7. Nuclear waste shipping container response to severe accident conditions, A brief critique of the modal study

    SciTech Connect

    Audin, L.

    1990-12-01

    The Modal Study (NUREG/CR-4829) attempts to upgrade the analysis of spent nuclear fuel transportation accidents, and to verify the validity of the present regulatory scheme of cask performance standards as a means to minimize risk. While an improvement over many prior efforts in this area (such as NUREG-0170), it unfortunately fails to create a realistic simulation either of a shipping cask, the severe conditions to which it could be subjected, or the potential damage to the spent fuel cargo during an accident. There are too many deficiencies in its analysis to allow acceptance of its results for the presumed cask design, and many pending changes in new containers, cargoes and shipping patterns will limit applicability of the Modal Study to future shipments. In essence, the Modal Study is a good start, but is too simplistic, incomplete, outdated and open to serious question to be used as the basis for any present-day environmental or risk assessment of spent fuel transportation. It needs to be redone, with peer review during its production and experimental verification of its assumptions, before it has any relevance to the shipments planned to Yucca Mountain. Finally, it must be expanded into a full risk assessment by inputing its radiological release fractions and probabilities into a valid dispersal simulation to properly determine the impact of its results. 51 refs.

  8. Dynamic Sliding Analysis of a Gravity Dam with Fluid-Structure-Foundation Interaction Using Finite Elements and Newmark's Sliding Block Analysis

    NASA Astrophysics Data System (ADS)

    Goldgruber, Markus; Shahriari, Shervin; Zenz, Gerald

    2015-11-01

    To reduce the natural hazard risks—due to, e.g., earthquake excitation—seismic safety assessments are carried out. Especially under severe loading, due to maximum credible or the so-called safety evaluation earthquake, critical infrastructure, as these are high dams, must not fail. However, under high loading local failure might be allowed as long as the entire structure does not collapse. Hence, for a dam, the loss of sliding stability during a short time period might be acceptable if the cumulative displacements after an event are below an acceptable value. This performance is not only valid for gravity dams but also for rock blocks as sliding is even more imminent in zones with higher seismic activity. Sliding modes cannot only occur in the dam-foundation contact, but also in sliding planes formed due to geological conditions. This work compares the qualitative possible and critical displacements for two methods, the well-known Newmark's sliding block analysis and a Fluid-Foundation-Structure Interaction simulation with the finite elements method. The results comparison of the maximum displacements at the end of the seismic event of the two methods depicts that for high friction angles, they are fairly close. For low friction angles, the results are differing more. The conclusion is that the commonly used Newmark's sliding block analysis and the finite elements simulation are only comparable for high friction angles, where this factor dominates the behaviour of the structure. Worth to mention is that the proposed simulation methods are also applicable to dynamic rock wedge problems and not only to dams.

  9. Aerosol Properties and Radiative Forcing over Kanpur during Severe Aerosol Loading Conditions

    SciTech Connect

    Kaskaoutis, D. G.; Sinha, P. R.; Vinoj, V.; Kosmopoulos, P. G.; Tripathi, S. N.; Misra, Amit; Sharma, M.; Singh, R. P.

    2013-11-01

    Atmospheric aerosols over India exhibit large spatio-temporal fluctuation driven by the local monsoon system, emission rates and seasonally-changed air masses. The northern part of India is well-known for its high aerosol loading throughout the year due to anthropogenic emissions, dust influence and biomass burning. On certain circumstances and, under favorable weather conditions, the aerosol load can be severe, causing significant health concerns and climate implications. The present work analyzes the aerosol episode (AE) days and examines the modification in aerosol properties and radiative forcing during the period 2001-2010 based on Kanpur-AERONET sun photometer data. As AEs are considered the days having daily-mean aerosol optical depth (AOD) above the decadal mean + 1 STD (standard deviation); the threshold value is defined at 0.928. The results identify 277 out of 2095 days (13.2%) of AEs over Kanpur, which are most frequently observed during post-monsoon (78 cases, 18.6%) and monsoon (76, 14.7%) seasons due to biomass-burning episodes and dust influence, respectively. On the other hand, the AEs in winter and pre-monsoon are lower in both absolute and percentage values (65, 12.5% and 58, 9.1%, respectively). The modification in aerosol properties on the AE days is strongly related to season. Thus, in post-monsoon and winter the AEs are associated with enhanced presence of fine-mode aerosols and Black Carbon from anthropogenic pollution and any kind of burning, while in pre-monsoon and monsoon seasons they are mostly associated with transported dust. Aerosol radiative forcing (ARF) calculated using SBDART shows much more surface (~-69 to -97 Wm-2) and Top of Atmosphere cooling (-20 to -30 Wm-2) as well as atmospheric heating (~43 to 71 Wm-2) during the AE days compared to seasonal means. These forcing values are mainly controlled by the higher AODs and the modified aerosol characteristics (Angstrom α, SSA) during the AE days in each season and may cause

  10. Extended survival of several organisms and amino acids under simulated martian surface conditions

    NASA Astrophysics Data System (ADS)

    Johnson, A. P.; Pratt, L. M.; Vishnivetskaya, T.; Pfiffner, S.; Bryan, R. A.; Dadachova, E.; Whyte, L.; Radtke, K.; Chan, E.; Tronick, S.; Borgonie, G.; Mancinelli, R. L.; Rothschild, L. J.; Rogoff, D. A.; Horikawa, D. D.; Onstott, T. C.

    2011-02-01

    Recent orbital and landed missions have provided substantial evidence for ancient liquid water on the martian surface as well as evidence of more recent sedimentary deposits formed by water and/or ice. These observations raise serious questions regarding an independent origin and evolution of life on Mars. Future missions seek to identify signs of extinct martian biota in the form of biomarkers or morphological characteristics, but the inherent danger of spacecraft-borne terrestrial life makes the possibility of forward contamination a serious threat not only to the life detection experiments, but also to any extant martian ecosystem. A variety of cold and desiccation-tolerant organisms were exposed to 40 days of simulated martian surface conditions while embedded within several centimeters of regolith simulant in order to ascertain the plausibility of such organisms' survival as a function of environmental parameters and burial depth. Relevant amino acid biomarkers associated with terrestrial life were also analyzed in order to understand the feasibility of detecting chemical evidence for previous biological activity. Results indicate that stresses due to desiccation and oxidation were the primary deterrent to organism survival, and that the effects of UV-associated damage, diurnal temperature variations, and reactive atmospheric species were minimal. Organisms with resistance to desiccation and radiation environments showed increased levels of survival after the experiment compared to organisms characterized as psychrotolerant. Amino acid analysis indicated the presence of an oxidation mechanism that migrated downward through the samples during the course of the experiment and likely represents the formation of various oxidizing species at mineral surfaces as water vapor diffused through the regolith. Current sterilization protocols may specifically select for organisms best adapted to survival at the martian surface, namely species that show tolerance to radical

  11. Severity of chronic Lyme disease compared to other chronic conditions: a quality of life survey

    PubMed Central

    Johnson, Lorraine; Wilcox, Spencer; Mankoff, Jennifer

    2014-01-01

    Overview. The Centers for Disease Control and Prevention (CDC) health-related quality of life (HRQoL) indicators are widely used in the general population to determine the burden of disease, identify health needs, and direct public health policy. These indicators also allow the burden of illness to be compared across different diseases. Although Lyme disease has recently been acknowledged as a major health threat in the USA with more than 300,000 new cases per year, no comprehensive assessment of the health burden of this tickborne disease is available. This study assesses the HRQoL of patients with chronic Lyme disease (CLD) and compares the severity of CLD to other chronic conditions. Methods. Of 5,357 subjects who responded to an online survey, 3,090 were selected for the study. Respondents were characterized as having CLD if they were clinically diagnosed with Lyme disease and had persisting symptoms lasting more than 6 months following antibiotic treatment. HRQoL of CLD patients was assessed using the CDC 9-item metric. The HRQoL analysis for CLD was compared to published analyses for the general population and other chronic illnesses using standard statistical methods. Results. Compared to the general population and patients with other chronic diseases reviewed here, patients with CLD reported significantly lower health quality status, more bad mental and physical health days, a significant symptom disease burden, and greater activity limitations. They also reported impairment in their ability to work, increased utilization of healthcare services, and greater out of pocket medical costs. Conclusions. CLD patients have significantly impaired HRQoL and greater healthcare utilization compared to the general population and patients with other chronic diseases. The heavy burden of illness associated with CLD highlights the need for earlier diagnosis and innovative treatment approaches that may reduce the burden of illness and concomitant costs posed by this

  12. Numerical Modelling of Tsunami Generated by Deformable Submarine Slides: Parameterisation of Slide Dynamics for Coupling to Tsunami Propagation Model

    NASA Astrophysics Data System (ADS)

    Smith, R. C.; Collins, G. S.; Hill, J.; Piggott, M. D.; Mouradian, S. L.

    2015-12-01

    Numerical modelling informs risk assessment of tsunami generated by submarine slides; however, for large-scale slides modelling can be complex and computationally challenging. Many previous numerical studies have approximated slides as rigid blocks that moved according to prescribed motion. However, wave characteristics are strongly dependent on the motion of the slide and previous work has recommended that more accurate representation of slide dynamics is needed. We have used the finite-element, adaptive-mesh CFD model Fluidity, to perform multi-material simulations of deformable submarine slide-generated waves at real world scales for a 2D scenario in the Gulf of Mexico. Our high-resolution approach represents slide dynamics with good accuracy, compared to other numerical simulations of this scenario, but precludes tracking of wave propagation over large distances. To enable efficient modelling of further propagation of the waves, we investigate an approach to extract information about the slide evolution from our multi-material simulations in order to drive a single-layer wave propagation model, also using Fluidity, which is much less computationally expensive. The extracted submarine slide geometry and position as a function of time are parameterised using simple polynomial functions. The polynomial functions are used to inform a prescribed velocity boundary condition in a single-layer simulation, mimicking the effect the submarine slide motion has on the water column. The approach is verified by successful comparison of wave generation in the single-layer model with that recorded in the multi-material, multi-layer simulations. We then extend this approach to 3D for further validation of this methodology (using the Gulf of Mexico scenario proposed by Horrillo et al., 2013) and to consider the effect of lateral spreading. This methodology is then used to simulate a series of hypothetical submarine slide events in the Arctic Ocean (based on evidence of historic

  13. Spatial distribution of thermodynamic conditions of severe storms in southwestern Europe

    NASA Astrophysics Data System (ADS)

    Gascón, E.; Merino, A.; Sánchez, J. L.; Fernández-González, S.; García-Ortega, E.; López, L.; Hermida, L.

    2015-10-01

    The Mid-Ebro Valley (MEV) is an area of the northeast Iberian Peninsula with a large number of hailstorms throughout the year. Therefore, new forecasting tools are required to improve the spatiotemporal detection of such storms. Using a database of 100 days with severe storms (SSs) over a 13-year period between 2001 and 2013, we obtained vertical profiles predicted by the WRF mesoscale model. A total of 31 indexes describing conditions of humidity, stability, helicity or precipitable water were obtained from the profiles and input to a binary logistic regression model. The regression model was applied using the forward stepwise method, which indicated that the stability indexes were the most accurate for SS in the study area. Of the 31 indexes, 5 were selected: Showalter index (SI), wind speed at 500 hPa (SPD500), dew point temperature at 850 hPa (Td850), relative helicity between 0 and 3 km (SREH3km), and wet bulb zero height (WBZ). Combination of these indexes in a logistic equation gives the probability of SS risk/no risk in the study area. Results of the logistic equation show a Probability of Detection (POD) of 0.94 and a False Alarm Ratio (FAR) of 0.22. The second part of the article describes regionalization of the study area by SS spatial distribution according to the logistic equation. Thus, using multivariate techniques, we used principal component analysis (PCA) in T-mode and posterior cluster analysis, getting four clusters according to the spatial distribution of SS thermodynamic behavior and the distribution of storms observed via radar data. Clusters 1 and 2 showed probabilities of hail occurrence that were lower than Clusters 3 and 4, mainly affecting the MEV and the eastern end of the study area. Likewise, the predicted hail area was more extensive in those last two clusters. These results provide a new tool that complements those previously developed for this study area, toward improving SS prediction and pinpointing these storms in space and in

  14. Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.

    PubMed

    Anyona, Samuel B; Kempaiah, Prakasha; Raballah, Evans; Ouma, Collins; Were, Tom; Davenport, Gregory C; Konah, Stephen N; Vulule, John M; Hittner, James B; Gichuki, Charity W; Ong'echa, John M; Perkins, Douglas J

    2011-12-01

    Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, interleukin-18 (IL-18) is important for regulating innate and acquired immunity in inflammatory and infectious diseases. As such, we selected two functional single-nucleotide polymorphisms (SNPs) in the IL-18 promoter (-137G→C [rs187238] and -607C→A [rs1946518]) whose haplotypes encompass significant genetic variation due to the presence of strong linkage disequilibrium among these variants. The relationship between the genotypes/haplotypes, SMA (hemoglobin [Hb], <5.0 g/dl], and longitudinal clinical outcomes were then investigated in Kenyan children (n = 719). Multivariate logistic regression analyses controlling for age, gender, sickle cell trait, glucose-6-phosphate dehydrogenase (G6PD) deficiency, HIV-1, and bacteremia revealed that carriage of the -607AA genotype was associated with protection against SMA (odds ratio [OR] = 0.440 [95% confidence interval {CI} = 0.21 to 0.90], P = 0.031) in children with acute infection. In contrast, carriers of the -137G/-607C (GC) haplotype had increased susceptibility to SMA (OR = 2.050 [95% CI = 1.04 to 4.05], P = 0.039). Measurement of IL-18 gene expression in peripheral blood leukocytes demonstrated that elevated IL-18 transcripts were associated with reduced hemoglobin concentrations (ρ = -0.293, P = 0.010) and that carriers of the "susceptible" GC haplotype had elevated IL-18 transcripts (P = 0.026). Longitudinal investigation of clinical outcomes over a 3-year follow-up period revealed that carriers of the rare CC haplotype (∼1% frequency) had 5.76 times higher mortality than noncarriers (P = 0.001). Results presented here demonstrate that IL-18 promoter haplotypes that condition elevated IL-18 gene products during acute infection are associated with increased risk of SMA. Furthermore, carriage of the

  15. Cross-polarization microwave radar return at severe wind conditions: laboratory model and geophysical model function.

    NASA Astrophysics Data System (ADS)

    Troitskaya, Yuliya; Abramov, Victor; Ermoshkin, Alexey; Zuikova, Emma; Kazakov, Vassily; Sergeev, Daniil; Kandaurov, Alexandr

    2014-05-01

    Satellite remote sensing is one of the main techniques of monitoring severe weather conditions over the ocean. The principal difficulty of the existing algorithms of retrieving wind based on dependence of microwave backscattering cross-section on wind speed (Geophysical Model Function, GMF) is due to its saturation at winds exceeding 25 - 30 m/s. Recently analysis of dual- and quad-polarization C-band radar return measured from satellite Radarsat-2 suggested that the cross-polarized radar return has much higher sensitivity to the wind speed than co-polarized back scattering [1] and conserved sensitivity to wind speed at hurricane conditions [2]. Since complete collocation of these data was not possible and time difference in flight legs and SAR images acquisition was up to 3 hours, these two sets of data were compared in [2] only statistically. The main purpose of this paper is investigation of the functional dependence of cross-polarized radar cross-section on the wind speed in laboratory experiment. Since cross-polarized radar return is formed due to scattering at small-scale structures of the air-sea interface (short-crested waves, foam, sprays, etc), which are well reproduced in laboratory conditions, then the approach based on laboratory experiment on radar scattering of microwaves at the water surface under hurricane wind looks feasible. The experiments were performed in the Wind-wave flume located on top of the Large Thermostratified Tank of the Institute of Applied Physics, where the airflow was produced in the flume with the straight working part of 10 m and operating cross section 0.40?0.40 sq. m, the axis velocity can be varied from 5 to 25 m/s. Microwave measurements were carried out by a coherent Doppler X-band (3.2 cm) scatterometer with the consequent receive of linear polarizations. Experiments confirmed higher sensitivity to the wind speed of the cross-polarized radar return. Simultaneously parameters of the air flow in the turbulent boundary layer

  16. Gravity Slides With Magnetic Braking

    NASA Technical Reports Server (NTRS)

    Goodrick, Thomas F.

    1995-01-01

    Slides with magnetic braking enable safe emergency descent from tall buildings, fire-truck ladders, towers, and like. According to concept, slide includes sled that moves along stationary aluminum track tilted against top of building. Sled holds set of permanent magnets at preset small distance from surface of track. Passenger stands on, sits on, or strapped to platform on sled. Release device at top of slide holds sled in place until passenger prepared for descent.

  17. The Timing of Online Lecture Slide Availability and Its Effect on Attendance, Participation, and Exam Performance

    ERIC Educational Resources Information Center

    Babb, Kimberley A.; Ross, Craig

    2009-01-01

    The use of PowerPoint slides has become an almost ubiquitous practice in university classrooms, however little research has examined whether the timing of lecture slide availability to students (either before or after lecture) affects classroom behaviour or exam performance. Using a 2 (slide availability condition) x 2 (course type)…

  18. Section 608 Rule Presentation Slides

    EPA Pesticide Factsheets

    This document presents slides informing the public about updates to the Section 608 concerning appliance disposal, refrigerant reclamation, technician certification, refrigerant sales restriction, recordkeeping, and repairing refrigerant leaks.

  19. Discriminative evaluative conditioning in the long-term after severe accidental injury.

    PubMed

    Oe, Misari; Schumacher, Sonja; Schnyder, Ulrich; Mueller-Pfeiffer, Christoph; Wilhelm, Frank H; Kuelen, Eveline; Martin-Soelch, Chantal

    2016-06-30

    Impairments in classical fear conditioning and deficits in discriminative learning are observed in posttraumatic stress disorder (PTSD). However, it is unknown whether similar impairments can be found with types of discriminative learning other than classical conditioning, such as evaluative conditioning (EC), in which the valence of a stimulus can be transferred to other stimuli. In this study, we investigated whether EC is also influenced by traumatic experiences independently of presence of PTSD. We tested 14 accident survivors with remitted PTSD, 14 survivors without PTSD, and 16 non-trauma controls. We used behavioral measures, psychophysiological indicators, and subjective ratings for tasks. General effects of learning were observed across groups and conditioning/extinction. Trauma controls had slower reaction times (RTs) to the aversive conditioned stimulus compared to appetitive conditioned and neutral stimuli, as well as slower RTs and increased accuracy during conditioning than during extinction. Remitted PTSD participants showed opposite results, demonstrating decreased accuracy and slower RTs during conditioning as compared to during extinction. No discriminative effect was found in the non-trauma controls and the remitted PTSD participants. These results suggest that a traumatic experience influences EC, and that this influence differs between individuals who have and have not developed PTSD after traumatic exposure.

  20. World petroleum assessment 2000; compiled PowerPoint slides

    USGS Publications Warehouse

    Ahlbrandt, Thomas S.

    2001-01-01

    The slides in this compilation have been produced for a number of presentations on the World Petroleum Assessment 20000. Many of the figures are taken directly form the publication "U.S. Geological Survey World Petroleum Assessment 2000" - Description and Results: USGS Digital Data Series DDS-60, 2000. Some of the slides are modifications of figures from DDS-60, some are new descriptive slides, and a few are new slides. Several of the slides appear to be duplicates, but in fact are slight modifications for format or content from the same image. Forty-one people participated in this effort as part of the World Energy Assessment Team. The full list of contributors is given ion DDS-60. 

  1. Shipping container response to severe highway and railway accident conditions: Appendices

    SciTech Connect

    Fischer, L.E.; Chou, C.K.; Gerhard, M.A.; Kimura, C.Y.; Martin, R.W.; Mensing, R.W.; Mount, M.E.; Witte, M.C.

    1987-02-01

    Volume 2 contains the following appendices: Severe accident data; truck accident data; railroad accident data; highway survey data and bridge column properties; structural analysis; thermal analysis; probability estimation techniques; and benchmarking for computer codes used in impact analysis. (LN)

  2. Germination and Growth of a Vegetable Exposed to Very Severe Environmental Conditions Experimentally Induced by High Voltage

    NASA Astrophysics Data System (ADS)

    Aoki, Takashi; Ikezawa, Shunjiro

    1982-09-01

    Ultra-high-voltage (UHV) transmission power lines are required in order to reduce transmission energy losses, and to transfer more power across long distances. However, the ecological and biological influence of UHV lines has not been documented well. Possible influences of UHV lines are: electro-magnetic field, ozone, NOx, and ion shower. The purpose of this study was to obtain information on the germination and growth of Raphanus sativus L.cv. Kaiware-daikon exposed to an experimental environment in which all the above influences at very severe intensity levels were working simultaneously. Several environmental conditions severer than those predicted for future UHV lines were set up, using a high voltage at 60 Hz. The germination and growth of this plant were suppressed under the experimental conditions used, the suppression being greater the severer the conditions. When the electric field is strong, corona discharge occurs at the tip of the plant.

  3. Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations

    PubMed Central

    Attur, Mukundan; Wang, Hwa-Ying; Kraus, Virginia Byers; Bukowski, Jack F; Aziz, Nazneen; Krasnokutsky, Svetlana; Samuels, Jonathan; Greenberg, Jeffrey; McDaniel, Gary; Abramson, Steven B; Kornman, Kenneth S

    2010-01-01

    Background A lack of biomarkers that identify patients at risk for severe osteoarthritis (OA) complicates development of disease-modifying OA drugs. Objective To determine whether inflammatory genetic markers could stratify patients with knee OA into high and low risk for destructive disease. Methods Genotype associations with knee OA severity were assessed in two Caucasian populations. Fifteen single nucleotide polymorphisms (SNPs) in six inflammatory genes were evaluated for association with radiographic severity and with synovial fluid mediators in a subset of the patients. Results Interleukin 1 receptor antagonist (IL1RN) SNPs (rs419598, rs315952 and rs9005) predicted Kellgren–Lawrence scores independently in each population. One IL1RN haplotype was associated with lower odds of radiographic severity (OR=0.15; 95% CI 0.065 to 0.349; p<0.0001), greater joint space width and lower synovial fluid cytokine levels. Carriage of the IL1RN haplotype influenced the age relationship with severity. Conclusion IL1RN polymorphisms reproducibly contribute to disease severity in knee OA and may be useful biomarkers for patient selection in disease-modifying OA drug trials. PMID:19934104

  4. Simulation of sliding of liquid droplets

    NASA Astrophysics Data System (ADS)

    Alen, Saif Khan; Farhat, Nazia; Rahman, Md. Ashiqur

    2016-07-01

    Numerical simulations of sliding behavior of liquid droplets on flat and periodic microgrooved surfaces with a range of groove geometry are conducted. A numerical model is developed which is capable of predicting the critical sliding angle of the drop by comparing the advancing and the receding angles obtained from numerical and experimental findings. The effect of microgroove topography, droplet size and inclination angle on the droplet sliding characteristics is analysed. Using an open-source platform (Surface Evolver), a 3D drop-shape model is developed to numerically determine the drop stability and contact angle hysteresis on tilted surfaces. In this numerical model, the three phase contact line of the drop is obtained by numerically calculating the vertex force and local contact angle at each vertex of the base contour. Several numerical models are developed based on various assumptions of base contour shape (circular or elliptical) and implementation of gravitational force to the droplet. Droplet shapes and critical sliding angles, obtained from these numerical models, are compared with those of experimental results and are found to be in very good agreement.

  5. Sliding valve pump

    SciTech Connect

    Rupert, C.L.

    1980-09-09

    A sliding valve pump for oil wells which includes a working barrel having a plurality of apertures located in spaced relationship in the wall thereof and a pair of travelling valves fitted within the working barrel and carried by a plunger rod, the valves also having a plurality of apertures or ports for periodic registration with the ports in the working barrel wall to facilitate pumping of fluid from an oil reservoir or pool to the surface. The pump is designed to pull the oil-gas mixture from the reservoir pool into the lower section of the working barrel on the downward stroke, and to subsequently pump the collected oil through the barrel and tubing upwardly toward the surface on the upward stroke.

  6. Awareness about a Life-Threatening Condition: Ectopic Pregnancy in a Network for Surveillance of Severe Maternal Morbidity in Brazil

    PubMed Central

    Filho, Edilberto Alves Rocha; Santana, Danielly Scaranello; Costa, Maria Laura; Haddad, Samira Maerrawe; Parpinelli, Mary Angela; Sousa, Maria Helena; Camargo, Rodrigo Soares; Pacagnella, Rodolfo Carvalho; Surita, Fernanda Garanhani; Pinto e Silva, Joao Luiz

    2014-01-01

    Objective. To assess occurrence of severe maternal complications associated with ectopic pregnancy (EP). Method. A multicenter cross-sectional study was conducted, with prospective surveillance of potentially life-threatening conditions (PLTC), maternal near miss (MNM), and maternal death (MD). EP complications, patient sociodemographic/obstetric characteristics, and conditions of severity management were assessed, estimating prevalence ratios with respective 95% CI. Factors independently associated with greater severity were identified using multiple regression analysis. Results. Of the 9.555 severe maternal morbidity patients, 312 women (3.3%) had complications after EP: 286 (91.7%) PLTC, 25 (8.0%) MNM, and 1 (0.3%) MD. Severe maternal outcome ratio (SMOR) was 0.3/1000 LB among EP cases and 10.8/1000 LB among other causes. Complicated EP patients faced a higher risk of blood transfusion, laparotomy, and lower risk of ICU admission and prolonged hospitalization than women developing complications resulting from other causes. Substandard care was the most common in more severe maternal morbidity and EP cases (22.7% MNM and MD versus 15% PLTC), although not significant. Conclusion. Increased maternal morbidity due to EP raised awareness about the condition and its impact on female reproductive life. No important risk factors for greater severity were identified. Care providers should develop specific guidelines and interventions to prevent severe maternal morbidity. PMID:24772441

  7. The Parent's Manual: A Manual of Supplementary Activities for Homebound Children with Severely Handicapping Conditions.

    ERIC Educational Resources Information Center

    Shrensky, Joan; And Others

    Designed for parents of homebound severely handicapped children, the manual presents games and activities for teaching preliminary skills (including body awareness), self help skills (such as washing hands, eating with a spoon, and brushing teeth), visual skills, language skills, and mathmatics skills. An introduction to each series of activities…

  8. Digital slide reproduction using densitometry

    NASA Astrophysics Data System (ADS)

    Fornaro, Peter R.; Gschwind, Rudolf; Rosenthaler, Lukas; Laurenson, Pip

    2002-06-01

    Many contemporary art collections contain important art installations where artists have used 35 mm slides as the primary medium. The number of ours these works are on show makes it necessary to regularly change the slides due to light fading. With funding from the Henry Moore Foundation. The conservation department at Tate initiated a project to examine ways in which digital technology could be used to aid the conservation of these works. The aim of the project was to place the original slides in cold storage and explored the possibility of using digital technology to make duplicate sets for display in the gallery. The reproductions needed to be of very high quality both in terms of resolution and color management. This paper discusses the use of densitometry to calibrate both device dependent and device independent systems for digitally reproducing 35 mm slides using a scanner and a film recorder and the effect of metamery when using slide films which employ different dyes.

  9. EVALUATION OF SEVERAL ASSESSMENT METHODS AS INDICATORS OF ESTUARINE ENVIRONMENTAL CONDITIONS

    EPA Science Inventory

    Researchers from U.S. EPA's Gulf Ecology Division have conducted a multi-year evaluation of the environmental condition of near-coastal areas affected by different types of stressors. Areas of study have included coastal rivers, transportation canals, residential canals and estua...

  10. The severe hailstorm in Germany on 28 July 2013: Characteristics and meteorological conditions

    NASA Astrophysics Data System (ADS)

    Kunz, Michael; Blahak, Ulrich; Handwerker, Jan; Schmidberger, Manuel; Mohr, Susanna; Jürgen Punge, Heinz; Fluck, Elody; Mühr, Bernhard

    2015-04-01

    At the end of July 2013, a series of violent thunderstorms with large hail, severe gusts and heavy rain affected several parts of Germany. These storms were triggered by pre-frontal convergence zones that formed within unstable air masses ahead of a low pressure system named Andreas. They marked the end of a short, but intense heat wave with temperatures up to 38°C. On 28 July, two supercell thunderstorms formed in the Rhine valley upstream of the Black Forest Mountains and moved almost parallel over the Swabian Jura and Bavaria. While the northern cell was weaker, the southern cell substantially intensified in the first hours and created hailstones with diameters of up to 8 cm. The hail fell mainly over a heavily populated region between the cities of Reutlingen and Tübingen with a high concentration of exposed assets. The track of that supercell ended in the north of Czech Republic and had a length of 500 km. Approximately 80,000 buildings were severely damaged by this major hailstorm. In total, insured loss was estimated to amount around 2 bn EURO, which is even higher than that related to the June flood in Germany in the same year. In this paper we investigate the temporal evolution and the characteristics of the most damaging supercell on 28 July by combining different data from remote sensing instruments such as radar, satellite, and lightning detection systems with ground-based observations and reports from eye-witnesses and a crop insurance company. Additional simulations with the Consortium for Small Scale Modelling COSMO-DE model with different setups reveal the important role of the cold pool for the triggering of the most severe hail cell. It will be shown that a major problem for simulating the storm was its initiation, while, once triggered artificially by 'warm bubbles', its track could be simulated rather well over several hours. Moreover, the operational COSMO version has some problems to simulate the observed reflectivity structure of the

  11. Sliding down an arbitrary curve in the presence of friction

    NASA Astrophysics Data System (ADS)

    González-Cataldo, Felipe; Gutiérrez, Gonzalo; Yáñez, Julio M.

    2017-02-01

    The motion of a block sliding on a curve is a well studied problem for flat and circular surfaces, but the necessary conditions for the block to leave the surface deserve a deeper treatment. In this article, we generalize this problem to an arbitrary surface, including the effects of friction, and provide a general expression to determine under what conditions a particle will leave the surface. An explicit integral form for the speed is given, which is analytically integrable for some cases. We demonstrate general criteria to determine the critical speed at which the particle immediately leaves the surface. Three curves, a circle, a cycloid, and a catenary, are analyzed in detail, revealing several interesting features.

  12. Robust sliding mode control applied to double Inverted pendulum system

    SciTech Connect

    Mahjoub, Sonia; Derbel, Nabil; Mnif, Faical

    2009-03-05

    A three hierarchical sliding mode control is presented for a class of an underactuated system which can overcome the mismatched perturbations. The considered underactuated system is a double inverted pendulum (DIP), can be modeled by three subsystems. Such structure allows the construction of several designs of hierarchies for the controller. For all hierarchical designs, the asymptotic stability of every layer sliding mode surface and the sliding mode surface of subsystems are proved theoretically by Barbalat's lemma. Simulation results show the validity of these methods.

  13. Line copy presentation slides with Kodalith.

    PubMed

    Kraushar, M F; Bailey, B A

    1978-08-01

    Line copy presentation slides with white letters on a blue background can be produced with a two-step process. The slides are more permanent than diazo slides, and the process is faster and less expensive.

  14. CFD Analysis of Mixing Characteristics of Several Fuel Injectors at Hypervelocity Flow Conditions

    NASA Technical Reports Server (NTRS)

    Drozda, Tomasz G.; Drummond, J. Philip; Baurle, Robert A.

    2016-01-01

    CFD analysis is presented of the mixing characteristics and performance of three fuel injectors at hypervelocity flow conditions. The calculations were carried out using the VULCAN-CFD solver and Reynolds-Averaged Simulations (RAS). The high Mach number flow conditions match those proposed for the planned experiments conducted as a part of the Enhanced Injection and Mixing Project (EIMP) at the NASA Langley Research Center. The EIMP aims to investigate scramjet fuel injection and mixing physics, improve the understanding of underlying physical processes, and develop enhancement strategies and functional relationships relevant to flight Mach numbers greater than eight. Because of the high Mach number flow considered, the injectors consist of a fuel placement device, a strut; and a fluidic vortical mixer, a ramp. These devices accomplish the necessary task of distributing and mixing fuel into the supersonic cross-flow albeit via different strategies. Both of these devices were previously studied at lower flight Mach numbers where they exhibited promising performance in terms of mixing efficiency and total pressure recovery. For comparison, a flush-wall injector is also included. This type of injector generally represents the simplest method of introducing fuel into a scramjet combustor, however, at high flight Mach number conditions, the dynamic pressure needed to induce sufficient fuel penetration may be difficult to achieve along with other requirements such as achieving desired levels of fuel-to-air mixing at the required equivalence ratio. The three injectors represent the baseline configurations planned for the experiments. The current work discusses the mixing flow field behavior and differences among the three fuel injectors, mixing performance as described by the mixing efficiency and the total pressure recovery, and performance considerations based on the thrust potential.

  15. The contribution of woody plant materials on the several conditions in a space environment

    NASA Astrophysics Data System (ADS)

    Tomita-Yokotani, Kaori; Baba, Keiichi; Suzuki, Toshisada; Kimura, Shunta; Sato, Seigo; Katoh, Hiroshi; Abe, Yusuke; Katayama, Takeshi

    Woody plant materials have several utilization elements in our habitation environment on earth. The studies of woody plants under a space-environment in the vegetable kingdom have a high contribution to the study of various and exotic environmental responses, too. Woody plants can produce an excess oxygen, woody materials for the living cabin, and provide a biomass by cultivating crops and other species of creatures. Tree material would become to be a tool in closed bio-ecosystems such as an environment in a space. We named the trees used as material for the experiment related to space environments “CosmoBon”, small tree bonsai. Japanese cherry tree, “Sakura”, is famous and lovely tree in Japan. One species of “Sakura”, “Mamezakura, Prunus incisa”, is not only lovely tree species, but also suitable tree for the model tree of our purpose. The species of Prunus incisa is originally grown in volcano environment. That species of Sakura is originally grown on Mt. Fuji aria, oligotrophic place. We will try to build the best utilization usage of woody plant under the space environment by “Mamezakura” as a model tree. Here, we will show the importance of uniformity of materials when we will use the tree materials in a space environment. We will also discuss that tree has a high possibility of utilization under the space environments by using our several results related to this research.

  16. Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016

    PubMed Central

    Antona, Denise; Kossorotoff, Manoëlle; Schuffenecker, Isabelle; Mirand, Audrey; Leruez-Ville, Marianne; Bassi, Clément; Aubart, Mélodie; Moulin, Florence; Lévy-Bruhl, Daniel; Henquell, Cécile; Lina, Bruno; Desguerre, Isabelle

    2016-01-01

    We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation. PMID:27918268

  17. An Airship Slide Rule

    NASA Technical Reports Server (NTRS)

    Weaver, E R; Pickering, S F

    1924-01-01

    This report prepared for the National Advisory Committee for Aeronautics, describes an airship slide rule developed by the Gas-Chemistry Section of the Bureau of Standards, at the request of the Bureau of Engineering of the Navy Department. It is intended primarily to give rapid solutions of a few problems of frequent occurrence in airship navigation, but it can be used to advantage in solving a great variety of problems, involving volumes, lifting powers, temperatures, pressures, altitudes and the purity of the balloon gas. The rule is graduated to read directly in the units actually used in making observations, constants and conversion factors being taken care of by the length and location of the scales. It is thought that with this rule practically any problem likely to arise in this class of work can be readily solved after the user has become familiar with the operation of the rule; and that the solution will, in most cases, be as accurate as the data warrant.

  18. Constitutive modelling of lubricants in concentrated contacts at high slide to roll ratios

    NASA Technical Reports Server (NTRS)

    Tevaarwerk, J. L.

    1985-01-01

    A constitutive lubricant friction model for rolling/sliding concentrated contacts such as gears and cams was developed, based upon the Johnson and Tevaarwerk fluid rheology model developed earlier. The friction model reported herein differs from the earlier rheological models in that very large slide to roll ratios can now be accommodated by modifying the thermal response of the model. Also the elastic response of the fluid has been omitted from the model, thereby making it much simpler for use in the high slide to roll contacts. The effects of this simplification are very minimal on the outcome of the predicted friction losses (less than 1%). In essence then the lubricant friction model developed for the high slide to roll ratios treats the fluid in the concentrated contact as consisting of a nonlinear viscous element that is pressure, temperature, and strain rate dependent in its shear response. The fluid rheological constants required for the prediction of the friction losses at different contact conditions are obtained by traction measurements on several of the currently used gear lubricants. An example calculation, using this model and the fluid parameters obtained from the experiments, shows that it correctly predicts trends and magnitude of gear mesh losses measured elsewhere for the same fluids tested here.

  19. Experimental investigation of fiberglass sandwich composite bending behaviour after severe aging condition

    NASA Astrophysics Data System (ADS)

    Gambaro, Carla; Lertora, Enrico; Mandolfino, Chiara

    2016-10-01

    Fiber Reinforced Polymer (FRP) sandwich panels are increasing their application as structural and non-structural components in all kinds of construction. By varying the material and thickness of core and face sheets, it is possible to obtain sandwich structures with different properties and performance. In particular, their advantages as lightweight and high mechanical properties make them extremely suitable for the transport industry. One of the most critical aspects regarding composite materials for engineering application is their performance after hygrothermal aging. The panels used in this study are composed of low density core, made by thermosetting resin foam with microspheres and glass fibers rolled until obtaining the required thickness, and two face sheets of the same material but realized in high density. In this study, the authors focused on the bending behaviour of this kind of sandwich panel, as received and after severe aging cycles.

  20. Predictive study on Tuscan extra virgin olive oil stability under several commercial conditions.

    PubMed

    Pagliarini, E; Zanoni, B; Giovanelli, G

    2000-04-01

    Industries aim to ensure extra virgin olive oil (EVOO) stability especially during commercial activities up to use by end consumers. The objective of this work was to set up predictive models of EVOO stability during commercial activities. Stability was studied on five lots of a batch of Tuscan virgin olive oil to simulate different commercial activities. Chemical, physical, and sensory analyses were carried out on EVOO samples. Experimental data were processed by multivariate analyses to select significant parameters and by regression analyses to set up kinetic models. A few parameters were found to be significant: hydroxytyrosol and tyrosol contents, carotenoid absorbance at 475 and 448 nm, alpha-tocopherol content, Rancimat induction time, and K(232). It was also shown that the stability of this EVOO was not significantly influenced by different uncontrolled bottling, transport, and storage conditions in supermarkets. Empirical models were set up to predict the time to reach a reference value for K(232).

  1. Bioactivity of Several Herbicides on the Nanogram Level Under Different Soil Moisture Conditions.

    PubMed

    Jung, S C; Kuk, Y I; Senseman, S A; Ahn, H G; Seong, C N; Lee, D J

    2015-01-01

    In this study, a double-tube centrifuge method was employed to determine the effects of soil moisture on the bioactivity of cafenstrole, pretilachlor, benfuresate, oxyfluorfen and simetryn. In general, the available herbicide concentration in soil solution (ACSS) showed little change as soil moisture increased for herbicides. The total available herbicide in soil solution (TASS) typically increased as soil moisture increased for all herbicides. The relationship between TASS and % growth rate based on dry weight showed strong linear relationships for both cafenstrole and pretilachlor, with r2 values of 0.95 and 0.84, respectively. Increasing TASS values were consistent with increasing herbicide water solubility, with the exception of the ionizable herbicide simetryn. Plant absorption and % growth rate exhibited a strong linear relationship with TASS. According to the results suggested that TASS was a better predictor of herbicidal bioactivity than ACSS for all herbicides under unsaturated soil moisture conditions.

  2. Classical and higher-order sliding mode attitude control for launch vehicle systems

    NASA Astrophysics Data System (ADS)

    Stott, James Edward, Jr.

    In determining flight controls for launch vehicle systems, several things must be taken into account. Launch vehicle systems can be expendable or reusable, carry crew or cargo, etc. Each of these launch vehicles maneuvers through a wide range of flight conditions and different mission profiles. Crewed vehicles must adhere to human rating requirements which limit the angular rates. Reusable launch vehicle systems must take into account actuator saturation during entry. Wind disturbances and plant uncertainties are major perturbations to the nominal state of any launch vehicle. An ideal controller is one that is robust enough to handle these uncertainties and external disturbances with limited control authority. One major challenge that exists in the design of these vehicles is the updating of old autopilot technology to new robust designs while also taking into account the different type of launch vehicle system employed. Sliding mode control algorithms that are inherently robust to external disturbances and plant uncertainties are very good candidates for improving the robustness and accuracy of the flight control systems. This dissertation focuses on systematically studying and developing a 'toolbox' of classical and higher-order sliding mode attitude control algorithms for different types of launch vehicle systems operating in uncertain conditions, including model uncertainties, actuator malfunctions, and external perturbations such as wind gusts. The developed toolbox comprises of time-varying sliding variables, classical and higher-order sliding mode attitude control algorithms, and observer techniques that yield novel sliding mode attitude control architectures. The proposed control toolbox allows achieving even higher standards of performance, reliability, safety, operability, and cost for launch vehicles over the current state of the art. Case studies include controlling the X-33 and SLV-X Launch Vehicles studied under NASA's Space Launch Initiative (SLI

  3. Severe loss of suitable climatic conditions for marsupial species in Brazil: challenges and opportunities for conservation.

    PubMed

    Loyola, Rafael D; Lemes, Priscila; Faleiro, Frederico V; Trindade-Filho, Joaquim; Machado, Ricardo B

    2012-01-01

    A wide range of evidences indicate climate change as one the greatest threats to biodiversity in the 21st century. The impacts of these changes, which may have already resulted in several recent species extinction, are species-specific and produce shifts in species phenology, ecological interactions, and geographical distributions. Here we used cutting-edge methods of species distribution models combining thousands of model projections to generate a complete and comprehensive ensemble of forecasts that shows the likely impacts of climate change in the distribution of all 55 marsupial species that occur in Brazil. Consensus projections forecasted range shifts that culminate with high species richness in the southeast of Brazil, both for the current time and for 2050. Most species had a significant range contraction and lost climate space. Turnover rates were relatively high, but vary across the country. We also mapped sites retaining climatic suitability. They can be found in all Brazilian biomes, especially in the pampas region, in the southern part of the Brazilian Atlantic Forest, in the north of the Cerrado and Caatinga, and in the northwest of the Amazon. Our results provide a general overview on the likely effects of global climate change on the distribution of marsupials in the country as well as in the patterns of species richness and turnover found in regional marsupial assemblages.

  4. The ability of silicide coating to delay the catastrophic oxidation of vanadium under severe conditions

    NASA Astrophysics Data System (ADS)

    Chaia, N.; Mathieu, S.; Rouillard, F.; Vilasi, M.

    2015-02-01

    V-4Cr-4Ti vanadium alloy is a potential cladding material for sodium-cooled fast-neutron reactors (SFRs). However, its affinity for oxygen and the subsequent embrittlement that oxygen induces causes a need for an oxygen diffusion barrier, which can be obtained by manufacturing a multi-layered silicide coating. The present work aims to evaluate the effects of thermal cycling (using a cyclic oxidation device) and tensile and compressive stresses (using the three-point flexure test) on the coated alloy system. Tests were performed in air up to 1100 °C, which is 200 °C higher than the accidental temperature for SFR applications. The results showed that the VSi2 coating was able to protect the vanadium substrate from oxidation for more than 400 1-h cycles between 1100 °C and room temperature. The severe bending applied to the coated alloy at 950 °C using a load of 75 MPa did not lead to specimen breakage. It can be suggested that the VSi2 coating has mechanical properties compatible with the V-4Cr-4Ti alloy for SFR applications.

  5. Severe Loss of Suitable Climatic Conditions for Marsupial Species in Brazil: Challenges and Opportunities for Conservation

    PubMed Central

    Loyola, Rafael D.; Lemes, Priscila; Faleiro, Frederico V.; Trindade-Filho, Joaquim; Machado, Ricardo B.

    2012-01-01

    A wide range of evidences indicate climate change as one the greatest threats to biodiversity in the 21st century. The impacts of these changes, which may have already resulted in several recent species extinction, are species-specific and produce shifts in species phenology, ecological interactions, and geographical distributions. Here we used cutting-edge methods of species distribution models combining thousands of model projections to generate a complete and comprehensive ensemble of forecasts that shows the likely impacts of climate change in the distribution of all 55 marsupial species that occur in Brazil. Consensus projections forecasted range shifts that culminate with high species richness in the southeast of Brazil, both for the current time and for 2050. Most species had a significant range contraction and lost climate space. Turnover rates were relatively high, but vary across the country. We also mapped sites retaining climatic suitability. They can be found in all Brazilian biomes, especially in the pampas region, in the southern part of the Brazilian Atlantic Forest, in the north of the Cerrado and Caatinga, and in the northwest of the Amazon. Our results provide a general overview on the likely effects of global climate change on the distribution of marsupials in the country as well as in the patterns of species richness and turnover found in regional marsupial assemblages. PMID:23029452

  6. Effect of sea sprays on air-sea momentum exchange at severe wind conditions

    NASA Astrophysics Data System (ADS)

    Troitskaya, Yu.; Ezhova, E.; Semenova, A.; Soustova, I.

    2012-04-01

    Wind-wave interaction at extreme wind speed is of special interest now in connection with the problem of explanation of the sea surface drag saturation at the wind speed exceeding 30 m/s. The idea on saturation (and even reduction) of the coefficient of aerodynamic resistance of the sea surface at hurricane wind speed was first suggested in [1] on the basis of theoretical analysis of sensitivity of maximum wind speed in a hurricane to the ratio of the enthalpy and momentum exchange coefficients. Both field [2-4] and laboratory [5] experiments confirmed that at hurricane wind speed the sea surface drag coefficient is significantly reduced in comparison with the parameterization obtained at moderate to strong wind conditions. Two groups of possible theoretical mechanisms for explanation of the effect of the sea surface drag reduction can be specified. In the first group of models developed in [6,7], the sea surface drag reduction is explained by peculiarities of the air flow over breaking waves. Another approach more appropriate for the conditions of developed sea exploits the effect of sea drops and sprays on the wind-wave momentum exchange. Papers[8,9] focused on the effect of the sea drops on stratification of the air-sea boundary layer similar to the model of turbulent boundary layer with the suspended particles [10], while papers [11-13] estimated the momentum exchange of sea drops and air-flow. A mandatory element of the spray induced momentum flux is a parameterization of the momentum exchange between droplets and air flow, which determines the "source function" in the momentum balance equation. In this paper a model describing the motion of a spume droplet, the wind tear away from the crest of a steep surface wave, and then falling into the water. We consider two models for the injection of droplets into the air flow. The first one assumes that the drop starts from the surface at the orbital velocity of the wave. In the second model we consider droplets from

  7. Comparison of several traps for catching German cockroaches (Dictyoptera: Blattellidae) under laboratory conditions.

    PubMed

    Smith, L M; Appel, A G

    2008-02-01

    German cockroach, Blattella germanica (L.) (Dictyoptera: Blattellidae), catch by five types of traps and modifications of each, were tested under controlled laboratory conditions. Cockroach catch differed significantly among traps. Lo-line trap caught the greatest number of cockroaches in the test arena for each size class (23% small nymphs, 39% of gravid females, and 60% of other size classes in the experimental arena). Jar traps caught the least number of cockroaches in the test arena for each size class (range, 7-23% of each size class trapped). Modifications of traps also altered catch of cockroaches. Food bait tablets increased catch significantly; however, increases were small (<10%). Size of traps did not affect catch; whole traps or half traps caught the same number of cockroaches. Jar traps were much less effective than sticky traps, catching only half the number of cockroaches as sticky traps. A thin layer of petrolatum was a more effective barrier in jar traps to cockroach escape than powdered Olancha clay. Traps with petrolatum caught about twice as many cockroaches as traps with clay. Trapping of any of six life stages was not significantly affected by catch of any of the other stages. Rather, trap catch of each life stage was dependent on the number of that life stage available in the experimental arenas. In conclusion, of the traps tested, the Lo-line trap was the most sensitive for measuring cockroach catch, whereas the Detector trap (one third of trap) was the most economical trap (greatest sensitivity for lowest cost).

  8. Analysis and modeling of extreme temperatures in several cities in northwestern Mexico under climate change conditions

    NASA Astrophysics Data System (ADS)

    García-Cueto, O. Rafael; Cavazos, M. Tereza; de Grau, Pamela; Santillán-Soto, Néstor

    2014-04-01

    The generalized extreme value distribution is applied in this article to model the statistical behavior of the maximum and minimum temperature distribution tails in four cities of Baja California in northwestern Mexico, using data from 1950-2010. The approach used of the maximum of annual time blocks. Temporal trends were included as covariates in the location parameter (μ), which resulted in significant improvements to the proposed models, particularly for the extreme maximum temperature values in the cities of Mexicali, Tijuana, and Tecate, and the extreme minimum temperature values in Mexicali and Ensenada. These models were used to estimate future probabilities over the next 100 years (2015-2110) for different time periods, and they were compared with changes in the extreme (P90th and P10th) percentiles of maximum and minimum temperature scenarios for a set of six general circulation models under low (RCP4.5) and high (RCP8.5) radiative forcings. By the end of the twenty-first century, the scenarios of the changes in extreme maximum summer temperature are of the same order in both the statistical model and the high radiative scenario (increases of 4-5 °C). The low radiative scenario is more conservative (increases of 2-3 °C). The winter scenario shows that minimum temperatures could be less severe; the temperature increases suggested by the probabilistic model are greater than those projected for the end of the century by the set of global models under RCP4.5 and RCP8.5 scenarios. The likely impacts on the region are discussed.

  9. Wear behaviour of cross-linked polyethylene assessed in vitro under severe conditions.

    PubMed

    Affatato, Saverio; Bersaglia, Gianluca; Rocchi, Mirko; Taddei, Paola; Fagnano, Concezio; Toni, Aldo

    2005-06-01

    The polyethylene (PE) for hip implants presents serious clinical problems; the production of debris may induce adverse tissue reactions that may lead to extensive bone loss around the implant and consequently osteolysis and implant loosening. Several attempts have been made to improve the wear properties of ultra-high molecular weight polyethylene (UHMWPE). More recently the attention of various researchers has been focused on cross-linked polyethylene (XLPE), due to its improved wear resistance with respect to conventional UHMWPE. This study was aimed at comparing the wear performances of clinically available acetabular liners (Zimmer Inc.) made of electron beam XLPE and conventional UHMWPE. To evaluate the influence of the material properties on wear, conventional UHMWPE and XLPE acetabular cups were tested against deliberately scratched CoCrMo femoral heads (Ra = 0.12-0.14 microm) in a hip joint wear simulator run for 3 million cycles with bovine calf serum as lubricant. Gravimetric measurements revealed significant differences between the wear behaviours of the two sets of acetabular cups: XLPE exhibited a wear rate about 40 times lower than conventional UHMWPE. Raman spectroscopy coupled to partial least-squares analysis was used to evaluate the possible crystallinity changes induced by mechanical stress (and thus the material wear resistance): only the UHMWPE cup which showed the highest weight loss displayed significant crystallinity changes. These results were correlated to the thickness of the plasticity-induced damage layer. The wear debris produced during the tests were isolated according to a validated protocol and imaged by scanning electron microscopy . The wear particles produced by XLPE were smaller than those produced by UHMWPE; the latter were observed as fibrillar and agglomerated particles. The mean equivalent circle diameter was 0.71 and 0.26 microm for UHMWPE and XLPE, respectively.

  10. Patterns of nocturnal rehydration in root tissues of Vaccinium corymbosum L. under severe drought conditions

    PubMed Central

    Valenzuela-Estrada, Luis R.; Richards, James H.; Diaz, Andres; Eissensat, David M.

    2009-01-01

    Although roots in dry soil layers are commonly rehydrated by internal hydraulic redistribution during the nocturnal period, patterns of tissue rehydration are poorly understood. Rates of nocturnal rehydration were examined in roots of different orders in Vaccinium corymbosum L. ‘Bluecrop’ (Northern highbush blueberry) grown in a split-pot system with one set of roots in relatively moist soil and the other set of roots in dry soil. Vaccinium is noted for a highly branched and extremely fine root system. It is hypothesized that nocturnal root tissue rehydration would be slow, especially in the distal root orders because of their greater hydraulic constraints (smaller vessel diameters and fewer number of vessels). Vaccinium root hydraulic properties delayed internal water movement. Even when water was readily available to roots in the wet soil and transpiration was minimal, it took a whole night-time period of 12 h for the distal finest roots (1st to 4th order) under dry soil conditions to reach the same water potentials as fine roots in moist soil (1st to 4th order). Even though roots under dry soil equilibrated with roots in moist soil, the equilibrium point reached before sunrise was about –1.2 MPa, indicating that tissues were not fully rehydrated. Using a single-branch root model, it was estimated that individual roots exhibiting the lowest water potentials in dry soil were 1st order roots (distal finest roots of the root system). However, considered at the branch level, root orders with the highest hydraulic resistances corresponded to the lowest orders of the permanent root system (3rd-, 4th-, and 5th-order roots), thus indicating possible locations of hydraulic safety control in the root system of this species. PMID:19188275

  11. Patterns of nocturnal rehydration in root tissues of Vaccinium corymbosum L. under severe drought conditions.

    PubMed

    Valenzuela-Estrada, Luis R; Richards, James H; Diaz, Andres; Eissensat, David M

    2009-01-01

    Although roots in dry soil layers are commonly rehydrated by internal hydraulic redistribution during the nocturnal period, patterns of tissue rehydration are poorly understood. Rates of nocturnal rehydration were examined in roots of different orders in Vaccinium corymbosum L. 'Bluecrop' (Northern highbush blueberry) grown in a split-pot system with one set of roots in relatively moist soil and the other set of roots in dry soil. Vaccinium is noted for a highly branched and extremely fine root system. It is hypothesized that nocturnal root tissue rehydration would be slow, especially in the distal root orders because of their greater hydraulic constraints (smaller vessel diameters and fewer number of vessels). Vaccinium root hydraulic properties delayed internal water movement. Even when water was readily available to roots in the wet soil and transpiration was minimal, it took a whole night-time period of 12 h for the distal finest roots (1st to 4th order) under dry soil conditions to reach the same water potentials as fine roots in moist soil (1st to 4th order). Even though roots under dry soil equilibrated with roots in moist soil, the equilibrium point reached before sunrise was about -1.2 MPa, indicating that tissues were not fully rehydrated. Using a single-branch root model, it was estimated that individual roots exhibiting the lowest water potentials in dry soil were 1st order roots (distal finest roots of the root system). However, considered at the branch level, root orders with the highest hydraulic resistances corresponded to the lowest orders of the permanent root system (3rd-, 4th-, and 5th-order roots), thus indicating possible locations of hydraulic safety control in the root system of this species.

  12. Coating for hot sliding seals

    NASA Technical Reports Server (NTRS)

    Stock, J.

    1979-01-01

    Heat resistant paint is effective surface coating for sliding seals that must operate at elevated temperatures. Economical paint is easy to apply, offers minimal friction, and improves reliability of seals.

  13. Droplet sampling of an oil-based and two water-based antievaporant ultra-low volume insecticide formulations using Teflon- and magnesium oxide-coated slides.

    PubMed

    Chaskopoulou, Alexandra; Latham, Mark D; Pereira, Roberto M; Koehler, Philip G

    2013-06-01

    We estimated the diameters below which 50% and 90% of the volume of droplets exist (Dv50 and Dv90, respectively) of 1 oil-based (Permanone 30-30) and 2 water-based (AquaReslin, Aqua-K-Othrine) antievaporant aerosols (with the Film Forming Aqueous Spray Technology [FFAST]) using Teflon- and magnesium oxide (MgO)-coated slides and determined whether the aging of the droplets on the slides (up to 60 min) exhibited any significant effect on Dv50 and Dv90 calculations. There were no significant differences in either Dv50 or Dv90 estimates on MgO-coated slides at 0 min and 60 min for all 3 products tested. On Teflon-coated slides, the only product that showed significant difference between 0 min and 60 min in both Dv50 and Dv90 estimates was Aqua-K-Othrine, perhaps due to a difference in formulation components. Specifically, both values corresponding to Dv50 and Dv90 at 60 min decreased by approximately 50% when compared to the values at 0 min. For the other 2 products, AquaReslin and Permanone, aging of droplets on Teflon up to 60 min did not have any significant effect on Dv50 and Dv90 values. To further investigate the behavior of Aqua-K-Othrine droplets on Teflon-coated slides we observed the droplets immediately after spraying and at 10-min intervals under different conditions of temperature and humidity. The majority of the shrinkage occurred within the 1st 10 min after impaction on the slides under all conditions tested. So in most field situations where slides are read several hours or days after collection, this shrinkage would not be observed. The MgO-coated slides should be the preferred field method for sampling droplets of Aqua-K-Othirne with the FFAST antievaporant technology.

  14. The decline of mountain permafrost and the occurrence of recent large debris slides in Iceland

    NASA Astrophysics Data System (ADS)

    Saemundsson, Thorsteinn; Kristinn Helgason, Jon; Petursson, Halldor

    2014-05-01

    During the last decade several, somewhat unusual, debris slides have occurred in Iceland. Most of these slides occurred in the Tröllaskagi peninsula in central north Iceland as well as in the eastern part of the island, and their starting zones are all located above 750-800 m. In most of them large blocks of frozen sediments have been observed in the slide material. The temperature rise which has been observed in Iceland during the last decades has lead to discussions about the present permafrost condition in Iceland and the possible decline of mountain permafrost. Recent studies at the Orravatnsrústir palsa site, in the highlands north of the Hofsjökull icecap give clear indications of decreasing of the permafrost during the last decade or so (Saemundsson et al. 2012). In 2011 and 2012 two large debris slides occurred in northern Iceland. In 2011 a huge slide fell from the Torfufell Mountain in the Eyjafjörður area and in 2012 another one fell from the Móafellshyrna Mountain in the Fljót area. In both these cases the slides originated at about 750-800 m a.s.l. and large chunks of frozen sediments transported down the mountain sides. The Torfufell debris slide fell on the 14th of October 2011, after exceptionally warm summer and unusually rainy fall. The slide originated along a 200 m long fissure at 800 m.a.s.l in a NW facing slope. Big blocks of frozen sediments located within the landslide debris material were traced back to crown of the landslide. The, Móafellshyrna debris slide fell on the 20th of September 2012, occurred after an unusually warm and dry summer with record amount of sunshine hours, followed by month of intense precipitation and earthquake activity in N-Iceland. The slide originated in a 200 m wide cirque at 750 m height in the NW slope of the mountain where a frozen solid debris cone slid or crept off a 100 m high rock face into a steep water saturated talus slope. The frozen sediments at 750 m height give clear indication of mountain

  15. Anhydrobiosis in yeast: FT-IR spectroscopic studies of yeast grown under conditions of severe oxygen limitation.

    PubMed

    Grube, Mara; Gavare, Marita; Rozenfelde, Linda; Rapoport, Alexander

    2014-01-01

    Anhydrobiosis is a unique state of living organisms when metabolism is temporarily and reversibly delayed in response to the extreme desiccation of cells. The production of dry active preparations of yeast grown under anaerobic conditions is not currently possible because preparations are extremely sensitive to the dehydration procedure, though they could be very helpful in different biotechnological processes, including bioethanol production. To characterize mechanisms responsible for such sensitivity to the dehydration procedure, Fourier transform infrared spectroscopy was used to study the composition of aerobically grown yeast Saccharomyces cerevisiae resistant to dehydration and grown under conditions of severe oxygen limitation and sensitive to dehydration. Results indicated that significantly lower amounts of lipids in cells, grown under conditions of severe oxygen limitation, may be related to the mechanisms of sensitivity. Dehydration of both resistant and sensitive S. cerevisiae cells was accompanied by similar changes in main cellular compounds. Amounts of nucleic acids and proteins decreased slightly, whereas that of lipids and carbohydrates increased. Artificially reduced sensitivity to dehydration in S. cerevisiae cells, grown under conditions of severe oxygen limitation, led to the increase in the lipid concentration. The chemical composition of S. cerevisiae membranes is proposed to dictate the resistance to dehydration in resistant and sensitive cells.

  16. Recent slope mobilizations in the Storegga Slide area

    NASA Astrophysics Data System (ADS)

    Berndt, C.; Crutchley, G.; Karstens, J.; Dumke, I.; Duennbier, K.

    2012-12-01

    With ~3500 km3 of mobilized material the Storegga Slide off mid-Norway is one of the largest known sub-marine slope failures. It occurred approximately 8150 years ago and there is strong evidence suggesting that the slide caused a large tsunami that propagated through the North Atlantic and affected the coasts of Norway, Iceland and the U.K. In the Nyegga area along the northern side wall of the slide numerous shallow faults exist. These faults detach within the top 100 m below the sea floor at various stratigraphic levels below, at, and above the main slide plain of the Storegga Slide. Previous studies proposed that these faults are evidence for partial slope movements during the Storegga Slide event indicating that the adjacent slopes were deformed due to the stress variations caused by the Storegga Slide. New high-resolution Parasound data that we have collected in May 2012 onboard RV Meteor show offsets of reflectors that are buried less than 3 m below the sea floor. Assuming that the sedimentation rates derived from a near-by Marion Dufresne sediment core, can be extrapolated to the study area, these reflector offsets suggest that the faults are younger than the Storegga Slide. Given a several million year-long history of repeated slope failures in the area it is important to obtain more precise dates for the activity of the faults in order to assess if these faults can be used as an indicator for future slope failures in the area or if they are the result of small-scale adjustments of the head wall topography in the wake of the Storegga Slide.

  17. Behaviorally-inhibited temperament is associated with severity of PTSD symptoms and faster eyeblink conditioning in veterans

    PubMed Central

    Myers, Catherine E.; VanMeenen, Kirsten M.; McAuley, J. Devin; Beck, Kevin D.; Pang, Kevin C. H.; Servatius, Richard J.

    2012-01-01

    Prior studies have sometimes demonstrated facilitated acquisition of classically-conditioned responses and/or resistance to extinction in post-traumatic stress disorder (PTSD). However, it is unclear whether these behaviors are acquired as a result of PTSD or exposure to trauma, or reflect pre-existing risk factors that confer vulnerability for PTSD. Here, we examined classical eyeblink conditioning and extinction in veterans self-assessed for current PTSD symptoms, exposure to combat, and the personality trait of behavioral inhibition (BI), a risk factor for PTSD. 128 veterans were recruited (mean age 51.2 years; 13.3% female); 126 completed self-assessment, with 25.4% reporting a history of exposure to combat and 30.9% reporting severe, current PTSD symptoms (PTSS). PTSD symptom severity was correlated with current BI (R2=0.497) and PTSS status could be predicted based on current BI and combat history (80.2% correct classification). A subset of the veterans (n=87) also completed eyeblink conditioning. Among veterans without PTSS, childhood BI was associated with faster acquisition; veterans with PTSS showed delayed extinction, under some conditions. These data demonstrate a relationship between current BI and PTSS, and suggest that the facilitated conditioning sometimes observed in PTSD patients may partially reflect personality traits such as childhood BI that pre-date and contribute to vulnerability for PTSD. PMID:21790343

  18. A novel adaptive sliding mode control with application to MEMS gyroscope.

    PubMed

    Fei, Juntao; Batur, Celal

    2009-01-01

    This paper presents a new adaptive sliding mode controller for MEMS gyroscope; an adaptive tracking controller with a proportional and integral sliding surface is proposed. The adaptive sliding mode control algorithm can estimate the angular velocity and the damping and stiffness coefficients in real time. A proportional and integral sliding surface, instead of a conventional sliding surface is adopted. An adaptive sliding mode controller that incorporates both matched and unmatched uncertainties and disturbances is derived and the stability of the closed-loop system is established. The numerical simulation is presented to verify the effectiveness of the proposed control scheme. It is shown that the proposed adaptive sliding mode control scheme offers several advantages such as the consistent estimation of gyroscope parameters including angular velocity and large robustness to parameter variations and external disturbances.

  19. Experimental testing of total knee replacements with UHMW-PE inserts: impact of severe wear test conditions.

    PubMed

    Zietz, Carmen; Reinders, Joern; Schwiesau, Jens; Paulus, Alexander; Kretzer, Jan Philippe; Grupp, Thomas; Utzschneider, Sandra; Bader, Rainer

    2015-03-01

    Aseptic implant loosening due to inflammatory reactions to wear debris is the main reason for the revision of total knee replacements (TKR). Hence, the decrease in polyethylene wear particle generation from the articulating surfaces is aimed at improving implant design and material. For preclinical testing of new TKR systems standardized wear tests are required. However, these wear tests do not reproduce the entire in vivo situation, since the pattern and amount of wear and subsequent implant failure are underestimated. Therefore, daily activity, kinematics, implant aging and position, third-body-wear and surface properties have to be considered to estimate the wear of implant components in vivo. Hence, severe test conditions are in demand for a better reproduction of the in vivo situation of TKR. In the present article an overview of different experimental wear test scenarios considering clinically relevant polyethylene wear situations using severe test conditions is presented.

  20. Engineering theory of slide processes in the design of earth dams on a soft ground foundation

    SciTech Connect

    Krasil'nikov, N.A.

    1987-11-01

    This paper discusses the slope stability and landslide propensity of several hydroelectric plant earth dams throughout the Soviet Union from the standpoint of slide theory and compares the research of several Soviet institutions into this problem with existing standards and recommendations on dam stability and reliability. The comparisons are made for earth dams having a soft ground foundation under static loading conditions. Applicable properties are discussed for a wide range of soils and rocks including clays, loams, sands, alluvials, and soft and hard gravels. Seismic effects are not discussed.

  1. The sliding-helix voltage sensor

    PubMed Central

    Peyser, Alexander; Nonner, Wolfgang

    2012-01-01

    The voltage sensor (VS) domain of voltage-gated ion channels underlies electrical excitability of living cells. We simulate a mesoscale model of the VS domain to determine the functional consequences of some of its physical elements. Our mesoscale model is based on VS charges, linear dielectrics and whole-body motion, applied to an S4 ‘sliding helix’. The electrostatics under voltage-clamped boundary conditions are solved consistently using a boundary element method. Based on electrostatic configurational energy, statistical-mechanical expectations of the experimentally observable relation between displaced charge and membrane voltage are predicted. Consequences of the model are investigated for variations of: S4 configuration (α- and 310-helical), countercharge alignment with S4 charges, protein polarizability, geometry of the gating canal, screening of S4 charges by the baths, and fixed charges located at the bath interfaces. The sliding helix VS domain has an inherent electrostatic stability in the explored parameter space: countercharges present in the region of weak dielectric always retain an equivalent S4 charge in that region but allow sliding movements displacing 3 to 4 e0. That movement is sensitive to small energy variations (< 2kT) along the path dependent on a number of electrostatic parameters tested in our simulations. These simulations show how the slope of the relation between displaced charge and voltage could be tuned in a channel. PMID:22907204

  2. Applications and challenges of digital pathology and whole slide imaging.

    PubMed

    Higgins, C

    2015-07-01

    Virtual microscopy is a method for digitizing images of tissue on glass slides and using a computer to view, navigate, change magnification, focus and mark areas of interest. Virtual microscope systems (also called digital pathology or whole slide imaging systems) offer several advantages for biological scientists who use slides as part of their general, pharmaceutical, biotechnology or clinical research. The systems usually are based on one of two methodologies: area scanning or line scanning. Virtual microscope systems enable automatic sample detection, virtual-Z acquisition and creation of focal maps. Virtual slides are layered with multiple resolutions at each location, including the highest resolution needed to allow more detailed review of specific regions of interest. Scans may be acquired at 2, 10, 20, 40, 60 and 100 × or a combination of magnifications to highlight important detail. Digital microscopy starts when a slide collection is put into an automated or manual scanning system. The original slides are archived, then a server allows users to review multilayer digital images of the captured slides either by a closed network or by the internet. One challenge for adopting the technology is the lack of a universally accepted file format for virtual slides. Additional challenges include maintaining focus in an uneven sample, detecting specimens accurately, maximizing color fidelity with optimal brightness and contrast, optimizing resolution and keeping the images artifact-free. There are several manufacturers in the field and each has not only its own approach to these issues, but also its own image analysis software, which provides many options for users to enhance the speed, quality and accuracy of their process through virtual microscopy. Virtual microscope systems are widely used and are trusted to provide high quality solutions for teleconsultation, education, quality control, archiving, veterinary medicine, research and other fields.

  3. Experimental results from containment piping bellows subjected to severe accident conditions. Volume 1, Results from bellows tested in `like-new` conditions

    SciTech Connect

    Lambert, L.D.; Parks, M.B.

    1994-09-01

    Bellows are an integral part of the containment pressure boundary in nuclear power plants. They are used at piping penetrations to allow relative movement between piping and the containment wall, while minimizing the load imposed on the piping and wall. Piping bellows are primarily used in steel containments; however, they have received limited use in some concrete (reinforced and prestressed) containments. In a severe accident they may be subjected to pressure and temperature conditions that exceed the design values, along with a combination of axial and lateral deflections. A test program to determine the leak-tight capacity of containment penetration bellows is being conducted under the sponsorship of the US Nuclear Regulatory Commission at Sandia National Laboratories. Several different bellows geometries, representative of actual containment bellows, have been subjected to extreme deflections along with pressure and temperature loads. The bellows geometries and loading conditions are described along with the testing apparatus and procedures. A total of thirteen bellows have been tested, all in the `like-new` condition. (Additional tests are planned of bellows that have been subjected to corrosion.) The tests showed that bellows are capable of withstanding relatively large deformations, up to, or near, the point of full compression or elongation, before developing leakage. The test data is presented and discussed.

  4. Outcomes of Severe Combined Immunodeficiency Patients Treated with Hematopoietic Stem Cell Transplantation with and without Pre-conditioning

    PubMed Central

    Patel, Niraj C.; Chinen, Javier; Rosenblatt, Howard M.; Hanson, I. Celine; Krance, Robert A.; Paul, Mary E.; Abramson, Stuart L.; Noroski, Lenora M.; Davis, Carla M.; Seeborg, Filiz O.; Foster, Samuel B.; Leung, Kathryn S.; Brown, Betty S.; Ritz, Jerome; Shearer, William T.

    2011-01-01

    Background The effect of pre-transplant conditioning upon the long-term outcomes of patients receiving hematopoietic stem cell transplantation (HSCT) for severe combined immunodeficiency (SCID) has not been completely determined. Objective To assess the outcomes of 23 mostly conditioned SCID patients and compare their outcomes to 25 nonconditioned SCID transplanted patients previously reported. Methods In the present study, we reviewed the medical records of these 23 consecutive mostly conditioned SCID patients transplanted between 1998 and 2007. Results Eighteen patients (median age at transplant 10 [range 0.8–108] mo) received haploidentical mismatched related donor, matched unrelated donor, or mismatched unrelated donor transplants, 17 of whom received pretransplant conditioning and one was not conditioned, 13 (72%) engrafted and survive a median of 3.8 [1.8–9.8] yr, 5 of 13 (38%) require IVIG, and 6 of 6 age-eligible children attend school. Of five recipients (median age at transplant 7 [range 2–23] mo) of matched related donor transplants, all 5 engrafted and survive a median of 7.5 [range 1.5–9.5] yr, 1 requires IVIG, and 3 of 3 age-eligible children attend school. Gene mutations were known in 16 cases: IL2γR in 7 patients, IL7αR in 4 patients, RAG1 in 2 patients, ADA in 2 patients, and AK2 in 1 patient. Early outcomes and quality of life of the previous non-conditioned vs. the present conditioned cohorts were not statistically different but longer-term follow-up is necessary for confirmation. Conclusions HSCT in SCID patients results in engraftment, long-term survival, and a good quality of life for the majority of patients with or without pre-transplant conditioning. PMID:19895994

  5. Severe Obesity and Comorbid Condition Impact on the Weight-Related Quality of Life of the Adolescent Patient

    PubMed Central

    Zeller, Meg H.; Inge, Thomas H.; Modi, Avani C.; Jenkins, Todd M.; Michalsky, Marc P.; Helmrath, Michael; Courcoulas, Anita; Harmon, Carroll M.; Rofey, Dana; Baughcum, Amy; Austin, Heather; Price, Karin; Xanthakos, Stavra A.; Brandt, Mary L.; Horlick, Mary; Buncher, Ralph

    2014-01-01

    Objectives To assess links between comorbid health status, severe excess weight, and weight-related quality of life (WRQOL) in adolescents with severe obesity and undergoing weight loss surgery (WLS) to inform clinical care. Study design Baseline (pre-operative) data from Teen-LABS, a prospective multicenter observational study of 242 adolescents with severe obesity (MdnBMI = 50.5 kg/m2; Mage=17.1; 75.6% female; 71.9% White) undergoing WLS, were utilized to examine the impact of demographics, body mass index (BMI), presence/absence of 16 comorbid conditions, and a cumulative comorbidity load (CLoad) index on WRQOL scores (Impact of Weight on Quality of Life-Kids; IWQOL-Kids). Results WRQOL was significantly lower than reference samples of healthy weight, overweight, and obese samples. Of 16 comorbid conditions, the most prevalent were dyslipidemia (74.4%), chronic pain (58.3%), and obstructive sleep apnea (56.6%). Males had a higher CLoad (p=.01) and BMI (p=.01), yet less impairment in total WRQOL (p<.01) than females. CLoad was a significant predictor of male WRQOL. For females, psychosocial (versus physical) comorbidities, BMI, and White race were significant predictors of WRQOL impairment. Less prevalent conditions (e.g., stress urinary incontinence) also emerged as contributors to lower WRQOL. Conclusions WRQOL impairment is substantial for adolescents with severe obesity undergoing WLS, with predictors varying by sex. These patient-data highlight targets for education, support, and adjunctive care referrals prior to WLS. Further, they provide a comprehensive empirical base for understanding heterogeneity in adolescent WRQOL outcomes following WLS, as weight and comorbidity profiles change over time. PMID:25556022

  6. Unresolved issues in hematopoietic stem cell transplantation for severe combined immunodeficiency: need for safer conditioning and reduced late effects.

    PubMed

    Horn, Biljana; Cowan, Morton J

    2013-05-01

    In this review we discuss recent outcomes of hematopoietic cell transplantation (HCT) for patients with severe combined immunodeficiency (SCID), including survival, T- and B-cell reconstitution, and late effects, particularly those related to genotype, use of conditioning regimen, and use of alternative donors. We identify the following issues that require additional data, which can be obtained through cooperative studies: outcomes of patients with SCID who did not receive conditioning before alternative donor HCT; outcomes of patients with SCID who did not receive graft-versus-host disease prophylaxis after T cell-replete HCT; late effects of HCT for patients with SCID, including neurocognitive outcomes, growth, and development; and their relationship to genotype and use of alkylating agents for conditioning. Careful follow-up of outcomes of all newborns receiving diagnoses based on newborn screening programs for SCID is essential because data are scarce on the effects of conditioning regimens in very young patients. A consensus on the definition of T- and B-cell recovery, criteria for additional "boosts," pharmacokinetic data of chemotherapy agents used in young children, and uniformity of the use of various chemotherapy agents are needed to compare results among institutions. Finally, development of new nontoxic conditioning regimens for HCT that can be safely used in very young children is required.

  7. Relative sliding durability of candidate high temperature fiber seal materials

    NASA Technical Reports Server (NTRS)

    Dellacorte, Christopher; Steinetz, Bruce M.

    1992-01-01

    The relative sliding durability behavior of six candidate ceramic fibers for high temperature sliding seal applications is reviewed and compared. Pin on disk tests were used to evaluate potential seal materials by sliding a tow or bundle of the candidate ceramic fiber against a superalloy test disk. Tests were conducted in air under a 2.65 N load, at a sliding velocity of 0.025 m/sec and at temperatures from 25 to 900 C. Friction was measured during the tests and fiber wear, indicated by the extent of fibers broken in the tow or bundle, was measured at the end of each test. For most of the fibers, friction and wear increase with test temperature. The relative fiber durability ranking correlates with tensile strength, indicating that tensile data, which is more readily available than sliding durability data, may be useful in predicting fiber wear behavior under various conditions. A dimensional analysis of the wear data shows that the fiber durability is related to a dimensionless durability ratio which represents the ratio of the fiber strength to the fiber stresses imposed by sliding. The analysis is applicable to fibers with similar diameters and elastic moduli. Based upon the results of the research program, three fiber candidates are recommended for further study as potential seal materials. They are a silicon based complex carbide-oxide fiber, an alumina-boria-silica and an aluminosilicate fiber.

  8. A novel glass slide filing system for pathology slides.

    PubMed

    Tsai, Steve; Kartono, Francisca; Shitabata, Paul K

    2007-07-01

    The availability of a collection of microscope glass slides for review is essential in the study and practice of pathology. A common problem facing many pathologists is the lack of a well-organized filing system. We present a novel system that would be easily accessible, informative, protective, and portable.

  9. Active sliding between cytoplasmic microtubules.

    PubMed

    Koonce, M P; Tong, J; Euteneuer, U; Schliwa, M

    Microtubules are versatile cellular polymers that play a role in cell shape determination and mediate various motile processes such as ciliary and flagellar bending, chromosome movements and organelle transport. That a sliding microtubule mechanism can generate force has been demonstrated in highly ordered structures such as axonemes, and microtubule-based force generation almost certainly contributes to the function of mitotic and meiotic spindles. Most cytoplasmic microtubule arrays, however, do not exhibit the structural regularity of axonemes and some spindles, and often appear disorganized. Yet many cellular activities (such as shape changes during morphogenesis, axonal extension and spindle assembly) involve highly coordinated microtubule behaviour and possibly require force generated by an intermicrotubule sliding mechanism, or perhaps use sliding to move microtubules rapidly into a protrusion for stabilization. Here we show that active sliding between cytoplasmic microtubules can occur in microtubule bundles of the amoeba Reticulomyxa. A force-producing mechanism of this sort could be used by this organism to facilitate the extension of cell processes and to generate the dynamic movements of the cytoplasmic network.

  10. Heavy duty complete extension slides

    NASA Astrophysics Data System (ADS)

    Bueno, José Ignacio; Vázquez, Javier

    2001-09-01

    The selection from available commercial market of a set of slides to be used in an habitable pressurised module in space, to draw a 660 mm box out of a rack, up to a completely extracted position in a safely supported configuration, seems in principle not to be a complicated task. That was the first approach taken in the design process of the telescopic guides of the Crew Work Bench (CWB) included in the Fluid Science Laboratory (FSL), part of "ESA Microgravity Facilities for Columbus" within the Columbus Orbital Facility (COF) of the International Space Station (ISS). Nevertheless, common space compatible requirements such as materials, specific environmental loads, available envelope, total weight, etc., can make the selection of telescopic slides from commercial market unfeasible. A specific development to design space compatible telescopic slides for the CWB was undertaken. A set of heavy duty space compatible telescopic slides were designed, manufactured and tested. They should be operative in both, 1-g environment and in orbit, and additionally should withstand an inadvertent astronaut kick or bump of 556 N in any direction.

  11. Herbaceous Ornamental Plants. Slide Script.

    ERIC Educational Resources Information Center

    Still, Steven

    This document, which is one in a series of curriculum materials that has been developed for use in Ohio agricultural education programs, contains 338 black-and-white photographs of a set of color slides and an accompanying script that, together, are intended as an aid in the study and identification of 150 different commercially important…

  12. Linear Motor With Air Slide

    NASA Technical Reports Server (NTRS)

    Johnson, Bruce G.; Gerver, Michael J.; Hawkey, Timothy J.; Fenn, Ralph C.

    1993-01-01

    Improved linear actuator comprises air slide and linear electric motor. Unit exhibits low friction, low backlash, and more nearly even acceleration. Used in machinery in which positions, velocities, and accelerations must be carefully controlled and/or vibrations must be suppressed.

  13. Recurrent sclerema in a young infant presenting with severe sepsis and severe pneumonia: an uncommon but extremely life-threatening condition.

    PubMed

    Afroze, Farzana; Pietroni, Mark A C; Chisti, Mohammod Jobayer

    2013-12-01

    A one month and twenty-five days old baby girl with problems of acute watery diarrhoea, severe dehydration, severe malnutrition, and reduced activity was admitted to the gastrointestinal unit of Dhaka Hospital of icddr,b. The differentials included dehydration, dyselectrolytaemia and severe sepsis. She was treated following the protocolized management guidelines of the hospital. However, within the next 24 hours, the patient deteriorated with additional problems of severe sepsis, severe pneumonia, hypoxaemia, ileus, and sclerema. She was transferred to the Intensive Care Unit (ICU). In the ICU, she was managed with oxygen supplementation, intravenous antibiotics, intravenous fluid, including a number of blood transfusions, vitamins, minerals, and diet. One month prior to this admission, she had been admitted to the ICU also with sclerema, septic shock, and urinary tract infection due to Escherichia coli and was discharged after full recovery. On both the occasions, she required repeated blood transfusions and aggressive antibiotic therapy in addition to appropriate fluid therapy and oxygen supplementation. She fully recovered from severe sepsis, severe malnutrition, ileus, sclerema, and pneumonia, both clinically and radiologically and was discharged two weeks after admission. Consecutive episodes of sclerema, resulting in two successive hospitalizations in a severely-malnourished young septic infant, have never been reported. However, this was managed successfully with blood transfusion, broad-spectrum antibiotics, and correction of electrolyte imbalance.

  14. Elevated corticosterone levels and severe weather conditions decrease parental investment of incubating Adélie penguins.

    PubMed

    Thierry, Anne-Mathilde; Massemin, Sylvie; Handrich, Yves; Raclot, Thierry

    2013-03-01

    Corticosterone, the main stress hormone in birds, mediates resource allocation, allowing animals to adjust their physiology and behaviour to changes in the environment. Incubation is a time and energy-consuming phase of the avian reproductive cycle. It may be terminated prematurely, when the parents' energy stores are depleted or when environmental conditions are severe. In this study, the effects of experimentally elevated baseline corticosterone levels on the parental investment of incubating male Adélie penguins were investigated. Incubation duration and reproductive success of 60 penguins were recorded. The clutches of some birds were replaced by dummy eggs, which recorded egg temperatures and rotation rates, enabling a detailed investigation of incubation behaviour. Corticosterone levels of treated birds were 2.4-fold higher than those of controls 18 days post treatment. Exogenous corticosterone triggered nest desertion in 61% of the treated birds; consequently reducing reproductive success, indicating that corticosterone can reduce or disrupt parental investment. Regarding egg temperatures, hypothermic events became more frequent and more pronounced in treated birds, before these birds eventually abandoned their nest. The treatment also significantly decreased incubation temperatures by 1.3°C and lengthened the incubation period by 2.1 days. However, the number of chicks at hatching was similar among successful nests, regardless of treatment. Weather conditions appeared to be particularly important in determining the extent to which corticosterone levels affected the behaviour of penguins, as treated penguins were more sensitive to severe weather conditions. This underlines the importance of considering the interactions of organisms with their environment in studies of animal behaviour and ecophysiology.

  15. Mitigative techniques and analysis of generic site conditions for ground-water contamination associated with severe accidents

    SciTech Connect

    Shafer, J.M.; Oberlander, P.L.; Skaggs, R.L.

    1984-04-01

    The purpose of this study is to evaluate the feasibility of using ground-water contaminant mitigation techniques to control radionuclide migration following a severe commercial nuclear power reactor accident. The two types of severe commercial reactor accidents investigated are: (1) containment basemat penetration of core melt debris which slowly cools and leaches radionuclides to the subsurface environment, and (2) containment basemat penetration of sump water without full penetration of the core mass. Six generic hydrogeologic site classifications are developed from an evaluation of reported data pertaining to the hydrogeologic properties of all existing and proposed commercial reactor sites. One-dimensional radionuclide transport analyses are conducted on each of the individual reactor sites to determine the generic characteristics of a radionuclide discharge to an accessible environment. Ground-water contaminant mitigation techniques that may be suitable, depending on specific site and accident conditions, for severe power plant accidents are identified and evaluated. Feasible mitigative techniques and associated constraints on feasibility are determined for each of the six hydrogeologic site classifications. The first of three case studies is conducted on a site located on the Texas Gulf Coastal Plain. Mitigative strategies are evaluated for their impact on contaminant transport and results show that the techniques evaluated significantly increased ground-water travel times. 31 references, 118 figures, 62 tables.

  16. Process-Based Characterizations of Subsurface Fluid Pressures for a Devil's Slide-like System

    NASA Astrophysics Data System (ADS)

    Thomas, M.; Loague, K.

    2014-12-01

    Coastal margins commonly host slope stability hazards that are influenced by hydrologic, geologic, and / or anthropogenic perturbations. A firm foundation for rigorously understanding the component contributions and process-based linkages among hydrologic and geomorphic response is comprehensive physics-based simulation. This study is motivated by the hydrologically-driven, creeping and episodic deep-seated bedrock slides that intersect a former section of the Pacific Coast Highway in the active landslide zone at Devil's Slide near Pacifica, California. For this study, deterministic-conceptual hydrogeologic simulation was employed to estimate fluid pressures for saturated three-dimensional (3D) subsurface systems. One-dimensional (1D) vertical, transient, variably-saturated simulations were conducted to establish the position of the water table (i.e., the upper boundary condition) for the 3D steady-state saturated problems which encode the geologic information for heterogeneous and anisotropic systems. The concept-development effort undertaken here demonstrates that, for a Devil's Slide-like system: (i) specific climatic conditions facilitate variable lag times associated with water-table dynamics, (ii) recharge is the most sensitive parameter to establish risk-averse estimates of fluid pressure, (iii) nuances in the 3D flow field related to fault zone characteristics markedly influence fluid pressures, and (iv) it is unlikely that seasonal fluctuations in the regional water table account for severe failure modes. The simulated fluid pressures encourage new interdisciplinary data discovery to investigate the spatial and temporal persistence of perched water in the study area. To capture event-driven failures for the Devil's Slide site, future efforts should develop characterizations of the unsaturated near surface with a rigor similar to the treatment of the saturated zone demonstrated by this study.

  17. Mechanism of shallow disrupted slide induced by extreme rainfall

    NASA Astrophysics Data System (ADS)

    Igwe, O.; Fukuoka, H.

    2010-12-01

    On July 16, 2010, extreme rainfall attacked western Japan and it caused very intense rainfall in Shobara city, Hiroshima prefecture, Japan. This rainfall induced hundreds of shallow disrupted slides and many of those became debris flows. One of this debris flows attacked a house standing in front of the exit of a channel, and claimed a resident’s life. Western Japan had repeatedly similar disasters in the past. Last event took place from July 19 to 26, 2009, when western Japan had a severe rainstorms and caused floods and landslides. Most of the landslides are debris slide - debris flows. Most devastated case took place in Hofu city, Japan. On July 21, extremely intense rainstorm caused numerous debris flows and mud flows in the hillslopes. Some of the debris flows destroyed residential houses and home for elderly people, and finally killed 14 residents. One of the unusual feature of both disaster was that landslides are distributed in very narrow area. In the 2010 Shobara city disaster, all of the landslides were distributed in 5 km x 3 km, and in the 2009 Hofu city disaster, most devastated zone of landslides were 10 km x 5 km. Rain radars of Meteorological Agency of Government of Japan detected the intense rainfall, however, the spatial resolution is usually larger than 5 km and the disaster area is too small to predict landslides nor issue warning. Furthermore, it was found that the growth rate of baby clouds was very quick. The geology of both areas are rhyolite (Shobara) and granite (Hofu), so the areal assessment of landslide hazard should be prepared before those intense rainfall will come. As for the Hofu city case, it was proved that debris flows took place in the high precipitation area and covered by covered by weathered granite sands and silts which is called “masa". This sands has been proved susceptible against landslides under extreme rainfall conditions. However, the transition from slide - debris flow process is not well revealed, except

  18. Projective synchronization of nonidentical fractional-order neural networks based on sliding mode controller.

    PubMed

    Ding, Zhixia; Shen, Yi

    2016-04-01

    This paper investigates global projective synchronization of nonidentical fractional-order neural networks (FNNs) based on sliding mode control technique. We firstly construct a fractional-order integral sliding surface. Then, according to the sliding mode control theory, we design a sliding mode controller to guarantee the occurrence of the sliding motion. Based on fractional Lyapunov direct methods, system trajectories are driven to the proposed sliding surface and remain on it evermore, and some novel criteria are obtained to realize global projective synchronization of nonidentical FNNs. As the special cases, some sufficient conditions are given to ensure projective synchronization of identical FNNs, complete synchronization of nonidentical FNNs and anti-synchronization of nonidentical FNNs. Finally, one numerical example is given to demonstrate the effectiveness of the obtained results.

  19. Approved Practices in Dairy Reproduction. Slide Script.

    ERIC Educational Resources Information Center

    Roediger, Roger D.; Barr, Harry L.

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with approved practices in dairy reproduction. Included in the guide are narrations for use with 200 slides dealing with the following topics: the importance of good reproduction, the male and female roles in reproduction, selection of…

  20. Linear Classification of Dairy Cattle. Slide Script.

    ERIC Educational Resources Information Center

    Sipiorski, James; Spike, Peter

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with principles of the linear classification of dairy cattle. Included in the guide are narrations for use with 63 slides, which illustrate the following areas that are considered in the linear classification system: stature, strength,…

  1. Techniques for Generating Instructional Slides. Final Report.

    ERIC Educational Resources Information Center

    Smith, Edgar A.; And Others

    Common in briefing presentations and in individualized instruction is the use of slides that present materials prepared on a typewriter (questions, instructions, outlines). To increase the efficiency and effectiveness of producing these kind of slides a procedure was developed to facilitate: (1) formatting copy to be used for slides; (2) using…

  2. Diseases of Landscape Ornamentals. Slide Script.

    ERIC Educational Resources Information Center

    Powell, Charles C.; Sydnor, T. Davis

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with recognizing and controlling diseases found on ornamental landscape plants. Included in the script are narrations for use with a total of 80 slides illustrating various foliar diseases (anthracnose, black spot, hawthorn leaf blight,…

  3. On-Line Retrieval of Clinical Slides.

    ERIC Educational Resources Information Center

    Milgrom, Linda

    The Physical Diagnosis Slide Bank, a collaborative project of the Universities of Washington, California at San Diego, and Arizona, utilizes an online interactive computer program to access a collection of over 2000 teaching clinical slides. Searchable data elements for each slide in the bank include subject descriptors (MeSH); accession number;…

  4. A Trial of Alemtuzumab Adjunctive Therapy in Allogeneic Hematopoietic Cell Transplantation with Minimal Conditioning for Severe Combined Immunodeficiency

    PubMed Central

    Dvorak, Christopher C.; Horn, Biljana N.; Puck, Jennifer M.; Adams, Stuart; Veys, Paul; Czechowicz, Agnieszka; Cowan, Morton J.

    2014-01-01

    For infants with severe combined immunodeficiency (SCID) the ideal conditioning regimen before allogeneic hematopoietic cell transplantation (HCT) would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with alemtuzumab monotherapy to overcome NK-cell mediated immunologic barriers to engraftment. We enrolled 4 patients who received CD34-selected haploidentical cells, two of whom failed to engraft donor T cells. The 2 patients who engrafted had delayed T cell reconstitution, despite rapid clearance of circulating alemtuzumab. Although well-tolerated, alemtuzumab failed to overcome immunologic barriers to donor engraftment. Furthermore, alemtuzumab may slow T cell development in patients with SCID in the setting of a T-cell depleted graft. PMID:24977928

  5. Effect of self-ion irradiation on the microstructural changes of alloy EK-181 in annealed and severely deformed conditions

    NASA Astrophysics Data System (ADS)

    Aydogan, E.; Chen, T.; Gigax, J. G.; Chen, D.; Wang, X.; Dzhumaev, P. S.; Emelyanova, O. V.; Ganchenkova, M. G.; Kalin, B. A.; Leontiva-Smirnova, M.; Valiev, R. Z.; Enikeev, N. A.; Abramova, M. M.; Wu, Y.; Lo, W. Y.; Yang, Y.; Short, M.; Maloy, S. A.; Garner, F. A.; Shao, L.

    2017-04-01

    EK-181 is a low-activation ferritic/martensitic steel that is an attractive candidate for in-core component materials for both fast reactors and fusion reactors. To assess the effect of microstructural engineering on radiation response, two variants of EK-181 were studied: one in an annealed condition and the other subject to severe plastic deformation. These specimens were irradiated with 3.5 MeV Fe self-ions up to 400 peak displacements per atom (dpa) at temperatures ranging from 400 °C to 500 °C. The deformation did not suppress swelling over the whole irradiated region. Instead, deformed samples showed higher swelling in the near-surface region. Void swelling was found to be correlated with grain boundary instability. Significant grain growth occurred when steady-state void growth started.

  6. Evaluation of resistance to change under different disrupter conditions in children with autism and severe intellectual disability.

    PubMed

    Lionello-DeNolf, Karen M; Dube, William V; McIlvane, William J

    2010-05-01

    Translational research inspired by behavioral momentum theory in the area of developmental disabilities has shown effects in individuals over a range of functioning levels. In the current study, behavioral momentum was assessed in 6 children diagnosed with autism and severe intellectual disability. In a repeated measures design, participants were exposed to relatively rich versus lean reinforcement contingencies in a multiple schedule with food reinforcers. This was followed by exposure to each of four disrupting conditions: prefeeding, presentation of a concurrent alternative stimulus, presentation of a movie, and the presence of a researcher dispensing response-independent reinforcers on a variable-time schedule. Consistently greater resistance to disruption in the component with the richer schedule occurred with the alternative stimulus disrupter but not with the other disrupters. These results suggest parameters that may be more (or less) effective if behavioral momentum inspired techniques are to be exploited in therapeutic environments.

  7. Pine Island Glacier - local flow mechanisms and basal sliding

    NASA Astrophysics Data System (ADS)

    Wilkens, N. M.; Kleiner, T.; Humbert, A.

    2013-12-01

    Pine Island Glacier is a fast moving outlet glacier in the West Antarctic Ice Sheet. Several tributaries feeding the central ice stream characterise the flow field structure of this glacier. In the past decades the glacier has shown acceleration, thinning and a significant grounding line retreat. These ongoing processes are coinciding with a concentrated mass loss in the area around Pine Island Glacier, the Amundsen Sea Embayment. The area is of additional interest due to its retrograde bed slope. The postulated instability of the setting turns the glacier into an even more suitable object for modelling studies. One major challenge encountered when modelling the flow field of Pine Island Glacier is to reproduce the locally varying flow pattern, with its many tributaries. Commonly this difficulty is overcome by inversion for parameters controlling basal sliding. Our study is aimed at connecting basal sliding again to physical parameters. To achieve this we conduct experiments of Pine Island Glacier with the diagnostic 3D full-Stokes model COMice. The model is thermo-mechanically coupled and implemented with the commercial finite-element package COMSOL Multiphysics©. We use remotely sensed surface velocity data to validate our results. In a first step, the model is used to identify dominant local mechanisms that drive the flow of the different tributaries. We identify connections between the basal topography, the basal temperature, the driving stress and the basal roughness distribution. The thus gained information is used to confine basal sliding. Areas with similar qualitative characteristics are identified, and constant-sliding assumptions made for those. Additionally, the basal roughness distribution is matched onto a basal sliding parameter. This way the sliding law is again brought closer to its original meaning. Our results are important for prognostic model experiments, as we connect basal sliding to locally varying basal properties, which might lead to

  8. Radiation-sensitive severe combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation--what to do?

    PubMed

    Cowan, Morton J; Gennery, Andrew R

    2015-11-01

    Defects in DNA cross-link repair 1C (DCLRE1C), protein kinase DNA activated catalytic polypeptide (PRKDC), ligase 4 (LIG4), NHEJ1, and NBS1 involving the nonhomologous end-joining (NHEJ) DNA repair pathway result in radiation-sensitive severe combined immunodeficiency (SCID). Results of hematopoietic cell transplantation for radiation-sensitive SCID suggest that minimizing exposure to alkylating agents and ionizing radiation is important for optimizing survival and minimizing late effects. However, use of preconditioning with alkylating agents is associated with a greater likelihood of full T- and B-cell reconstitution compared with no conditioning or immunosuppression alone. A reduced-intensity regimen using fludarabine and low-dose cyclophosphamide might be effective for patients with LIG4, NHEJ1, and NBS1 defects, although more data are needed to confirm these findings and characterize late effects. For patients with mutations in DCLRE1C (Artemis-deficient SCID), there is no optimal approach that uses standard dose-alkylating agents without significant late effects. Until nonchemotherapy agents, such as anti-CD45 or anti-CD117, become available, options include minimizing exposure to alkylators, such as single-agent low-dose targeted busulfan, or achieving T-cell reconstitution, followed several years later with a conditioning regimen to restore B-cell immunity. Gene therapy for these disorders will eventually remove the issues of rejection and graft-versus-host disease. Prospective multicenter studies are needed to evaluate these approaches in this rare but highly vulnerable patient population.

  9. Dry Sliding Wear Behaviour of Flyash Reinforced ZA-27 Alloy Based Metal Matrix Composites

    NASA Astrophysics Data System (ADS)

    Sharma, S. C.; Krishna, M.; Bhattacharyya, D.

    In the present investigation, an attempt has been made to evaluate the wear rate of ZA-27 alloy composites reinforced with fly ash particles from 1 to 3 wt% in steps of 1 wt%. The compo-casting method has been used to fabricate the composites using Raichur fly ash of average size 3-5 microns. The wear specimens are tested under dry conditions using a pin-on-disc sliding wear testing machine with wear loads of 20-120 N in steps of 20 N, and the sliding distances in the range of 0.5 km to 2.5 km. The results indicate that the wear rate of the composites is less than that of the matrix alloy and it further decreases with the increase in fly ash content. However, the material loss in terms of wear rate and wear volume increases with the increase in load and sliding distance, both in the cases of composites and the matrix alloy. An increase in the applied load increases the wear severity by changing the wear mechanism from abrasion to particle-cracking induced delamination wear. It is found that with the increase in fly ash content, the wear resistance increases monotonically. The observations have been explained using scanning electron microscope (SEM) analysis of the worn surfaces of the composites.

  10. Manual stage acquisition and interactive display of digital slides in histopathology.

    PubMed

    Gherardi, Alessandro; Bevilacqua, Alessandro

    2014-07-01

    More powerful PC architectures, high-resolution cameras working at increasing frame rates, and more and more accurate motorized microscopes have boosted new applications in the field of biomedicine and medical imaging. In histopathology, the use of digital slides (DSs) imaging through dedicated hardware for digital pathology is increasing for several reasons: digital annotation of suspicious lesions, recorded clinical history, and telepathology as a collaborative environment. In this paper, we propose the first method known in the literature for real-time whole slide acquisition and displaying conceived for conventional nonautomated microscopes. Differently from DS scanner, our software enables biologists and histopathologists to build and view the DS in real time while inspecting the sample, as they are accustomed to. In addition, since our approach is compliant with existing common microscope positions, provided with camera and PC, this could contribute to disseminate the whole slide technology in the majority of small labs not endowed with DS hardware facilities. Experiments performed with different histologic specimens (referring to tumor tissues of different body parts as well as to tumor cells), acquired under different setup conditions and devices, prove the effectiveness of our approach both in terms of quality and speed performances.

  11. Optimal sliding guidance algorithm for Mars powered descent phase

    NASA Astrophysics Data System (ADS)

    Wibben, Daniel R.; Furfaro, Roberto

    2016-02-01

    Landing on large planetary bodies (e.g. Mars) with pinpoint accuracy presents a set of new challenges that must be addressed. One such challenge is the development of new guidance algorithms that exhibit a higher degree of robustness and flexibility. In this paper, the Zero-Effort-Miss/Zero-Effort-Velocity (ZEM/ZEV) optimal sliding guidance (OSG) scheme is applied to the Mars powered descent phase. This guidance algorithm has been specifically designed to combine techniques from both optimal and sliding control theories to generate an acceleration command based purely on the current estimated spacecraft state and desired final target state. Consequently, OSG yields closed-loop trajectories that do not need a reference trajectory. The guidance algorithm has its roots in the generalized ZEM/ZEV feedback guidance and its mathematical equations are naturally derived by defining a non-linear sliding surface as a function of the terms Zero-Effort-Miss and Zero-Effort-Velocity. With the addition of the sliding mode and using Lyapunov theory for non-autonomous systems, one can formally prove that the developed OSG law is globally finite-time stable to unknown but bounded perturbations. Here, the focus is on comparing the generalized ZEM/ZEV feedback guidance with the OSG law to explicitly demonstrate the benefits of the sliding mode augmentation. Results show that the sliding guidance provides a more robust solution in off-nominal scenarios while providing similar fuel consumption when compared to the non-sliding guidance command. Further, a Monte Carlo analysis is performed to examine the performance of the OSG law under perturbed conditions.

  12. Measured performance of the heat exchanger in the NASA icing research tunnel under severe icing and dry-air conditions

    NASA Technical Reports Server (NTRS)

    Olsen, W.; Vanfossen, J.; Nussle, R.

    1987-01-01

    Measurements were made of the pressure drop and thermal perfomance of the unique refrigeration heat exchanger in the NASA Lewis Icing Research Tunnel (IRT) under severe icing and frosting conditions and also with dry air. This data will be useful to those planning to use or extend the capability of the IRT and other icing facilities (e.g., the Altitude Wind Tunnel-AWT). The IRT heat exchanger and refrigeration system is able to cool air passing through the test section down to at least a total temperature of -30 C (well below icing requirements), and usually up to -2 C. The system maintains a uniform temperature across the test section at all airspeeds, which is more difficult and time consuming at low airspeeds, at high temperatures, and on hot, humid days when the cooling towers are less efficient. The very small surfaces of the heat exchanger prevent any icing cloud droplets from passing through it and going through the tests section again. The IRT heat exchanger was originally designed not to be adversely affected by severe icing. During a worst-case icing test the heat exchanger iced up enough so that the temperature uniformaity was no worse than about +/- 1 deg C. The conclusion is that the heat exchanger design performs well.

  13. TRUMP-BD: A computer code for the analysis of nuclear fuel assemblies under severe accident conditions

    SciTech Connect

    Lombardo, N.J.; Marseille, T.J.; White, M.D.; Lowery, P.S.

    1990-06-01

    TRUMP-BD (Boil Down) is an extension of the TRUMP (Edwards 1972) computer program for the analysis of nuclear fuel assemblies under severe accident conditions. This extension allows prediction of the heat transfer rates, metal-water oxidation rates, fission product release rates, steam generation and consumption rates, and temperature distributions for nuclear fuel assemblies under core uncovery conditions. The heat transfer processes include conduction in solid structures, convection across fluid-solid boundaries, and radiation between interacting surfaces. Metal-water reaction kinetics are modeled with empirical relationships to predict the oxidation rates of steam-exposed Zircaloy and uranium metal. The metal-water oxidation models are parabolic in form with an Arrhenius temperature dependence. Uranium oxidation begins when fuel cladding failure occurs; Zircaloy oxidation occurs continuously at temperatures above 13000{degree}F when metal and steam are available. From the metal-water reactions, the hydrogen generation rate, total hydrogen release, and temporal and spatial distribution of oxide formations are computed. Consumption of steam from the oxidation reactions and the effect of hydrogen on the coolant properties is modeled for independent coolant flow channels. Fission product release from exposed uranium metal Zircaloy-clad fuel is modeled using empirical time and temperature relationships that consider the release to be subject to oxidation and volitization/diffusion ( bake-out'') release mechanisms. Release of the volatile species of iodine (I), tellurium (Te), cesium (Ce), ruthenium (Ru), strontium (Sr), zirconium (Zr), cerium (Cr), and barium (Ba) from uranium metal fuel may be modeled.

  14. Significance of grain sliding mechanisms for ductile deformation of rocks

    NASA Astrophysics Data System (ADS)

    Dimanov, A.; Bourcier, M.; Gaye, A.; Héripré, E.; Bornert, M.; Raphanel, J.; Ludwig, W.

    2013-12-01

    Ductile shear zones at depth present polyphase and heterogeneous rocks and multi-scale strain localization patterns. Most strain concentrates in ultramylonitic layers, which exhibit microstructural signatures of several concomitant deformation mechanisms. The latter are either active in volume (dislocation creep), or in the vicinity and along interfaces (grain sliding and solution mass transfer). Because their chronology of appearance and interactions are unclear, inference of the overall rheology seems illusory. We have therefore characterized over a decade the rheology of synthetic lower crustal materials with different compositions and fluid contents, and for various microstructures. Non-Newtonian flow clearly related to dominant dislocation creep. Conversely, Newtonian behavior involved grain sliding mechanisms, but crystal plasticity could be identified as well. In order to clarify the respective roles of these mechanisms we underwent a multi-scale investigation of the ductile deformation of rock analog synthetic halite with controlled microstructures. The mechanical tests were combined with in-situ optical microscopy, scanning electron microscopy and X ray computed tomography, allowing for digital image correlation (DIC) techniques and retrieval of full strain field. Crystal plasticity dominated, as evidenced by physical slip lines and DIC computed slip bands. Crystal orientation mapping allowed to identify strongly active easy glide {110} <110> systems. But, all other slip systems were observed as well, and especially near interfaces, where their activity is necessary to accommodate for the plastic strain incompatibilities between neighboring grains. We also evidenced grain boundary sliding (GBS), which clearly occurred as a secondary, but necessary, accommodation mechanism. The DIC technique allowed the quantification of the relative contribution of each mechanism. The amount of GBS clearly increased with decreasing grain size. Finite element (FE) modeling

  15. The Slide-Lecture: An Alternative to Chalkdust?

    ERIC Educational Resources Information Center

    Wilkins, S. A.

    Many instructors teaching large survey courses use the chalkboard to aid their lectures in spite of the waste of class time in writing and erasing, the clutter and confusion that may result, and the messiness of chalkdust. As an alternative, the slide-lecture method has been used for several years at Bossier Community College in teaching…

  16. Apparatus Would Stain Microscope Slides

    NASA Technical Reports Server (NTRS)

    Breeding, James D.

    1993-01-01

    Proposed apparatus meters specific amounts of fluid out of containers at specific times to stain microscope slides. Intended specifically for semiautomated staining of microbiological and hematological samples in microgravity, leakproof apparatus used in other environments in which technicians have little time to allocate to staining procedures and/or exposure to toxic staining agents or to micro-organisms to be stained hazardous. Apparatus adapted to perform almost any staining procedure and accommodates multiple staining reagents, useful for small or remote clinical laboratories.

  17. Design of anti-slide piles for slope stabilization in Wanzhou city, Three Gorges Area, China

    NASA Astrophysics Data System (ADS)

    Zhou, Chunmei; van Westen, Cees

    2013-04-01

    This study is related to the design of anti-slide piles for several landslides in Wanzhou city located in the Three Gorges area. Due to the construction of the Three Gorges Reservoir the hydro-geological conditions in this area have deteriorated significantly, leading to larger instability problems. China has invested a lot of money in slope stabilization measures for the treatment of landslides in the Three Gorges area. One of the methods for the stabilization of large landslides is the design of anti-sliding piles. This paper focuses on extensive slope stability analysis and modeling of the mechanical behavior of the landslide masses, and the parameters required for designing the number, size and dimensions of reinforced concrete stabilization piles. The study focuses on determining the rock parameters, anchor depth, and the pile and soil interaction coefficient. The study aims to provide guidelines for anti-slide pile stabilization works for landslides in the Wanzhou area. The research work contains a number of aspects. First a study is carried out on the distribution of pressures expected on the piles, using two different methods that take into account the expected pore water pressure and seismic acceleration. For the Ercengyan landslide , the Limit Equilibrium Method and Strength Reduction Method of FEM are compared through the results of the landslide pressure distributions on the piles and stress fields in the piles. The second component is the study of the required anchor depth of antislide piles, which is carried out using a statistical analysis with data from 20 landslides that have been controlled with anti-sliding piles. The rock characteristics of the anchor locations were obtained using laboratory tests, and a classification of rock mass quality is made for the anchors of antislide piles. The relationship between the critical anchor height and the angle of the landslide slip surface is determined. Two different methods are presented for the length

  18. A comparison of the dynamic stiffness of the Goldcrown GC-500 grinding machine for three slide designs

    SciTech Connect

    Bennett, J.G.; Goldman, P.; Williams, D.C.; Farrar, C.R.

    1994-01-01

    This report provides a summary of the results obtained from the calculations that compare the dynamic stiffness of three slide design systems for the Goldcrown GC-500 centerless grinder; it also describes the models and procedures used to develop the calculations, the assumptions made, and the details that went into performing this work. The authors developed analytical models of the three Goldcrown slide designs and performed several computational studies to determine the dynamic stiffness of the designs. The three slide systems are hereafter referred to as the plane slide, the INA slide, and the polymer-coated slide. The plane slide is the dovetail slide and way traditionally used in machine tool designs. The INA slide is a design created by Goldcrown using INA Bearing Company recirculating roller bearings, and dampers on a rail guideway. The polymer-coated slide is a design using a low friction polymer coating for a modified plane slide system. A study of the drawings indicated that a comparison could be made, within a reasonable amount of time and effort, that would be indicative of the dynamic stiffness of the three designs if the machine was modeled as being composed of the following seven structural components: (1) the base, (2) the swivel plate, (3) the lower slide, (4) the upper housing, (5) the regulating wheel housing, (6) the ball screw, and (7) the in-feed body.

  19. Automated single-slide staining device

    NASA Technical Reports Server (NTRS)

    Wilkins, J. R.; Mills, S. M. (Inventor)

    1977-01-01

    A simple apparatus and method is disclosed for making individual single Gram stains on bacteria inoculated slides to assist in classifying bacteria in the laboratory as Gram-positive or Gram-negative. The apparatus involves positioning a single inoculated slide in a stationary position and thereafter automatically and sequentially flooding the slide with increments of a primary stain, a mordant, a decolorizer, a counterstain and a wash solution in a sequential manner without the individual lab technician touching the slide and with minimum danger of contamination thereof from other slides.

  20. Pressure vessel sliding support unit and system using the sliding support unit

    DOEpatents

    Breach, Michael R.; Keck, David J.; Deaver, Gerald A.

    2013-01-15

    Provided is a sliding support and a system using the sliding support unit. The sliding support unit may include a fulcrum capture configured to attach to a support flange, a fulcrum support configured to attach to the fulcrum capture, and a baseplate block configured to support the fulcrum support. The system using the sliding support unit may include a pressure vessel, a pedestal bracket, and a plurality of sliding support units.

  1. Studying the Activities of Microorganisms in Soil Using Slides.

    ERIC Educational Resources Information Center

    Cullimore, D. Roy; Pipe, Annette E.

    1980-01-01

    Two implanted slide techniques are described by which activity of proteolylic bacteria and the growth of algae in the soil can be readily studied by school students using simple apparatus and methods. Variations are suggested for studying the effects of agricultural practices and environmental conditions on the soil bacteria and algae. (Author/DS)

  2. Global Trends in Environment and Development. Presentation Set [Slides].

    ERIC Educational Resources Information Center

    World Resources Inst., Washington, DC.

    This 50 slide set of presentation graphs and maps illustrates some of the major conditions and trends in population, agriculture, biodiversity, forests, water resources, energy, climate, and social and economic development that determine the state of the world's environment. Graphs and maps can be used by those in academic, professional, and…

  3. Whole-slide imaging: routine pathologic diagnosis.

    PubMed

    Cornish, Toby C; Swapp, Ryan E; Kaplan, Keith J

    2012-05-01

    Digital pathology systems offer pathologists an alternate, emerging mechanism to manage and interpret information. They offer increasingly fast and scalable hardware platforms for slide scanning and software that facilitates remote viewing, slide conferencing, archiving, and image analysis. Deployed initially and validated largely within the research and biopharmaceutical industries, WSI is increasingly being implemented for direct patient care. Improvements in image quality, scan times, and imageviewing browsers will hopefully allow pathologists to more seamlessly convert to digital pathology, much like our radiology colleagues have done before us. However, WSI creates both opportunities and challenges. Although niche applications of WSI technology for clinical, educational, and research purposes are clearly successful, it is evident that several areas still require attention and careful consideration before more widespread clinical adoption of WSI takes place. These include regulatory issues, development of standards of practice and validation guidelines, workflow modifications, as well as defining situations where WSI technology will really improve practice in a cost-effective way. Current progress on these and other issues, along with improving technology, will no doubt pave the way for increased adoption over the next decade, allowing the pathology community as a whole to harness the true potential of WSI for patient care. The digital decade will likely redefine how pathology is practiced and the role of the pathologist.

  4. Detection of tissue folds in whole slide images.

    PubMed

    Bautista, Pinky A; Yagi, Yukako

    2009-01-01

    In whole slide imaging (WSI) the quality of scanned images is an interplay between the hardware specifications of the scanning device and the condition of the tissue slide itself. Tissue artifacts such as folds and bubbles have been known to affect the efficiency of a whole slide scanning system in selecting the focus points wherein the presence of the said artifacts have been found to produce blur or unfocused images. Thus, for a whole slide scanning device to produce the best image quality, even with the presence of tissue artifacts, information on the location of these artifacts should be known such that they can be avoided in the selection of the focus points. In this paper we introduced an enhancement method to emphasize and detect the location of the tissue folds from whole slide images. Results of the experiments that we conducted on various H&E stained images that were scanned using different scanners show the robustness of the method to detect tissue folds.

  5. Sliding mode controller for a photovoltaic pumping system

    NASA Astrophysics Data System (ADS)

    ElOugli, A.; Miqoi, S.; Boutouba, M.; Tidhaf, B.

    2017-03-01

    In this paper, a sliding mode control scheme (SMC) for maximum power point tracking controller for a photovoltaic pumping system, is proposed. The main goal is to maximize the flow rate for a water pump, by forcing the photovoltaic system to operate in its MPP, to obtain the maximum power that a PV system can deliver.And this, through the intermediary of a sliding mode controller to track and control the MPP by overcoming the power oscillation around the operating point, which appears in most implemented MPPT techniques. The sliding mode control approach is recognized as one of the efficient and powerful tools for nonlinear systems under uncertainty conditions.The proposed controller with photovoltaic pumping system is designed and simulated using MATLAB/SIMULINK environment. In addition, to evaluate its performances, a classical MPPT algorithm using perturb and observe (P&O) has been used for the same system to compare to our controller. Simulation results are shown.

  6. An analytical model of dynamic sliding friction during impact

    NASA Astrophysics Data System (ADS)

    Arakawa, Kazuo

    2017-01-01

    Dynamic sliding friction was studied based on the angular velocity of a golf ball during an oblique impact. This study used the analytical model proposed for the dynamic sliding friction on lubricated and non-lubricated inclines. The contact area A and sliding velocity u of the ball during impact were used to describe the dynamic friction force Fd = λAu, where λ is a parameter related to the wear of the contact area. A comparison with experimental results revealed that the model agreed well with the observed changes in the angular velocity during impact, and λAu is qualitatively equivalent to the empirical relationship, μN + μη‧dA/dt, given by the product between the frictional coefficient μ and the contact force N, and the additional term related to factor η‧ for the surface condition and the time derivative of A.

  7. An analytical model of dynamic sliding friction during impact

    PubMed Central

    Arakawa, Kazuo

    2017-01-01

    Dynamic sliding friction was studied based on the angular velocity of a golf ball during an oblique impact. This study used the analytical model proposed for the dynamic sliding friction on lubricated and non-lubricated inclines. The contact area A and sliding velocity u of the ball during impact were used to describe the dynamic friction force Fd = λAu, where λ is a parameter related to the wear of the contact area. A comparison with experimental results revealed that the model agreed well with the observed changes in the angular velocity during impact, and λAu is qualitatively equivalent to the empirical relationship, μN + μη′dA/dt, given by the product between the frictional coefficient μ and the contact force N, and the additional term related to factor η′ for the surface condition and the time derivative of A. PMID:28054668

  8. Near-future pH conditions severely impact calcification, metabolism and the nervous system in the pteropod Heliconoides inflatus.

    PubMed

    Moya, Aurelie; Howes, Ella L; Lacoue-Labarthe, Thomas; Forêt, Sylvain; Hanna, Bishoy; Medina, Mónica; Munday, Philip L; Ong, Jue-Sheng; Teyssié, Jean-Louis; Torda, Gergely; Watson, Sue-Ann; Miller, David J; Bijma, Jelle; Gattuso, Jean-Pierre

    2016-12-01

    Shelled pteropods play key roles in the global carbon cycle and food webs of various ecosystems. Their thin external shell is sensitive to small changes in pH, and shell dissolution has already been observed in areas where aragonite saturation state is ~1. A decline in pteropod abundance has the potential to disrupt trophic networks and directly impact commercial fisheries. Therefore, it is crucial to understand how pteropods will be affected by global environmental change, particularly ocean acidification. In this study, physiological and molecular approaches were used to investigate the response of the Mediterranean pteropod, Heliconoides inflatus, to pH values projected for 2100 under a moderate emissions trajectory (RCP6.0). Pteropods were subjected to pHT 7.9 for 3 days, and gene expression levels, calcification and respiration rates were measured relative to pHT 8.1 controls. Gross calcification decreased markedly under low pH conditions, while genes potentially involved in calcification were up-regulated, reflecting the inability of pteropods to maintain calcification rates. Gene expression data imply that under low pH conditions, both metabolic processes and protein synthesis may be compromised, while genes involved in acid-base regulation were up-regulated. A large number of genes related to nervous system structure and function were also up-regulated in the low pH treatment, including a GABAA receptor subunit. This observation is particularly interesting because GABAA receptor disturbances, leading to altered behavior, have been documented in several other marine animals after exposure to elevated CO2 . The up-regulation of many genes involved in nervous system function suggests that exposure to low pH could have major effects on pteropod behavior. This study illustrates the power of combining physiological and molecular approaches. It also reveals the importance of behavioral analyses in studies aimed at understanding the impacts of low pH on marine

  9. Traction and film thickness measurements under starved elastohydrodynamic conditions

    NASA Technical Reports Server (NTRS)

    Wedeven, L. D.

    1974-01-01

    Traction measurements under starved elastohydrodynamic conditions were obtained for a point contact geometry. Simultaneous measurements of the film thickness and the locations of the inlet lubricant boundary were made optically. The thickness of a starved film for combination rolling and sliding conditions varies with the location of the inlet boundary in the same way found previously for pure rolling. A starved film was observed to possess greater traction than a flooded film for the same slide roll ratio. For a given slide roll ratio a starved film simply increases the shear rate in the Hertz region. The maximum shear rate depends on the degree of starvation and has no theoretical limit. Traction measurements under starved conditions were compared with flooded conditions under equivalent shear rates in the Hertz region. When the shear rates in the Hertz region were low and the film severely starved, the measured tractions were found to be much lower than expected.

  10. Effect of nontronite smectite clay on the chemical evolution of several organic molecules under simulated Mars surface UV radiation conditions

    NASA Astrophysics Data System (ADS)

    Poch, Olivier; Dequaire, Tristan; Stalport, Fabien; Jaber, Maguy; Lambert, Jean-François; Szopa, Cyril; Coll, Patrice

    2015-04-01

    The search for organic carbon-containing molecules at the surface of Mars, as clues of past habitability or remnants of life, is a major scientific goal for Mars exploration. Several lines of evidence, including the detection of phyllosilicates, suggest that early Mars offered favorable conditions for long-term sustaining of water. As a consequence, we can assume that in those days, endogenous chemical processes, or even primitive life, may have produced organic matter on Mars. Moreover, exogenous delivery from small bodies or dust particles is likely to have brought fresh organic molecules to the surface of Mars up today. Organic matter is therefore expected to be present at the surface/subsurface of the planet. But the current environmental conditions at the surface - UV radiation, oxidants and energetic particles - generate physico-chemical processes that may affect organic molecules. On the other hand, on Earth, phyllosilicates are known to accumulate and preserve organic matter. But are phyllosilicates efficient at preserving organic molecules under the current environmental conditions at the surface of Mars? We have monitored the qualitative and quantitative evolutions of glycine, urea and adenine interacting with the Fe3+-smectite clay nontronite, one of the most abundant phyllosilicates present at the surface of Mars, under simulated Martian surface ultraviolet light (190-400 nm), mean temperature (218 ± 2 K) and pressure (6 ± 1 mbar) in a laboratory simulation setup. We have tested organic-rich samples which may be representative of the evaporation of a warm little pond of liquid water having concentrated organics on Mars. For each molecule, we have observed how the nontronite influences the quantum efficiency of its photodecomposition and the nature of its solid evolution products. The results reveal a pronounced photoprotective effect of nontronite on the evolution of glycine and adenine: their efficiencies of photodecomposition are reduced by a factor

  11. Mediterranean savanna of Acacia caven (Mol) is still a sink of CO2 in spite of severe hydrological drought conditions

    NASA Astrophysics Data System (ADS)

    Bravo-Martínez, F.; Meza, F. J.

    2012-12-01

    An eddy covariance tower was set up to monitor net ecosystem exchange (NEE) on a mediterranean shrubland of Acacia caven (Mol) in October 2010. This ecosystem (commonly referred as "espinal") is one of the most abundant land covers of Chile's central valley (2.000.000 ha). The last two years (2010-2011) were characterized by the occurrence of a severe drought (rainfall deficit 56%) and a small increase in temperature evaluated using a climatic change index (Peterson, 2005). We also detected a strong reduction in vegetation index during this period (evaluated using MODIS imagery). The historical analysis of the enhanced vegetation index (EVI) and leaf area index (LAI) showed that water status of the acacia savanna were at a minimum during this period (record of 14 years of data). The annual balance of NEE of 2011 was -54gC m-2 y-1, which means that the espinal is a sink of atmospheric CO2 notwithstanding the many stressors on photosynthesis. Monthly analysis of NEE shows the strong dependence of ecosystem fluxes on phenological state. Maximum rates of assimilation are a consequence of grassland activity, whereas secondary picks during the year (late spring and early autumn) are attributed to the semideciduos leaf of A. caven. Climatic conditions during the study season, confirm the tremendous plasticity of Acacia caven and its role as a colonizer of degraded sclerophyll forest because it adaptation to water and thermal stress.

  12. Sliding seal materials for adiabatic engines

    NASA Technical Reports Server (NTRS)

    Lankford, J.

    1985-01-01

    The sliding friction coefficients and wear rates of promising carbide, oxide, and nitride materials were measured under temperature, environmental, velocity, loading conditions that are representative of the adiabatic engine environment. In order to provide guidance needed to improve materials for this application, the program stressed fundamental understanding of the mechanisms involved in friction and wear. Microhardness tests were performed on the candidate materials at elevated temperatures, and in atmospheres relevant to the piston seal application, and optical and electron microscopy were used to elucidate the micromechanisms of wear following wear testing. X-ray spectroscopy was used to evaluate interface/environment interactions which seemed to be important in the friction and wear process. Electrical effects in the friction and wear processes were explored in order to evaluate the potential usefulness of such effects in modifying the friction and wear rates in service. However, this factor was found to be of negligible significance in controlling friction and wear.

  13. Sliding through a superlight granular medium.

    PubMed

    Pacheco-Vázquez, F; Ruiz-Suárez, J C

    2009-12-01

    We explore the penetration dynamics of an intruder in a granular medium composed of expanded polystyrene spherical particles. Three features distinguish our experiment from others studied so far in granular physics: (a) the impact is horizontal, decoupling the effects of gravity and the drag force; (b) the density of the intruder rho(i) is up to 350 times larger than the density of the granular medium rho(m); and (c) the way the intruder moves through the material, sliding at the bottom of the column with small friction. Under these conditions we find that the final penetration D scales with (rho(i)/rho(m)) and the drag force Fd and D saturate with the height of the granular bed.

  14. Color accuracy and reproducibility in whole slide imaging scanners

    PubMed Central

    Shrestha, Prarthana; Hulsken, Bas

    2014-01-01

    Abstract We propose a workflow for color reproduction in whole slide imaging (WSI) scanners, such that the colors in the scanned images match to the actual slide color and the inter-scanner variation is minimum. We describe a new method of preparation and verification of the color phantom slide, consisting of a standard IT8-target transmissive film, which is used in color calibrating and profiling the WSI scanner. We explore several International Color Consortium (ICC) compliant techniques in color calibration/profiling and rendering intents for translating the scanner specific colors to the standard display (sRGB) color space. Based on the quality of the color reproduction in histopathology slides, we propose the matrix-based calibration/profiling and absolute colorimetric rendering approach. The main advantage of the proposed workflow is that it is compliant to the ICC standard, applicable to color management systems in different platforms, and involves no external color measurement devices. We quantify color difference using the CIE-DeltaE2000 metric, where DeltaE values below 1 are considered imperceptible. Our evaluation on 14 phantom slides, manufactured according to the proposed method, shows an average inter-slide color difference below 1 DeltaE. The proposed workflow is implemented and evaluated in 35 WSI scanners developed at Philips, called the Ultra Fast Scanners (UFS). The color accuracy, measured as DeltaE between the scanner reproduced colors and the reference colorimetric values of the phantom patches, is improved on average to 3.5 DeltaE in calibrated scanners from 10 DeltaE in uncalibrated scanners. The average inter-scanner color difference is found to be 1.2 DeltaE. The improvement in color performance upon using the proposed method is apparent with the visual color quality of the tissue scans. PMID:26158041

  15. Color accuracy and reproducibility in whole slide imaging scanners

    NASA Astrophysics Data System (ADS)

    Shrestha, Prarthana; Hulsken, Bas

    2014-03-01

    In this paper, we propose a work-flow for color reproduction in whole slide imaging (WSI) scanners such that the colors in the scanned images match to the actual slide color and the inter scanner variation is minimum. We describe a novel method of preparation and verification of the color phantom slide, consisting of a standard IT8- target transmissive film, which is used in color calibrating and profiling the WSI scanner. We explore several ICC compliant techniques in color calibration/profiling and rendering intents for translating the scanner specific colors to the standard display (sRGB) color-space. Based on the quality of color reproduction in histopathology tissue slides, we propose the matrix-based calibration/profiling and absolute colorimetric rendering approach. The main advantage of the proposed work-ow is that it is compliant to the ICC standard, applicable to color management systems in different platforms, and involves no external color measurement devices. We measure objective color performance using CIE-DeltaE2000 metric, where DeltaE values below 1 is considered imperceptible. Our evaluation 14 phantom slides, manufactured according to the proposed method, show an average inter-slide color difference below 1 DeltaE. The proposed work-flow is implemented and evaluated in 35 Philips Ultra Fast Scanners (UFS). The results show that the average color difference between a scanner and the reference is 3.5 DeltaE, and among the scanners is 3.1 DeltaE. The improvement on color performance upon using the proposed method is apparent on the visual color quality of the tissues scans.

  16. Scale effects in sliding friction: An experimental study

    SciTech Connect

    Blau, P.J.

    1991-07-24

    Solid friction is considered by some to be a fundamental property of two contacting materials, while others consider it to be a property of the larger tribosystem in which the materials are contained. A set of sliding friction experiments were designed to investigate the hypothesis that the unlubricated sliding friction between two materials is indeed a tribosystems-related property and that the relative influence of the materials properties or those of the machine on friction varies from one situation to another. Three tribometers were used: a friction microprobe (FMP), a typical laboratory-scale reciprocating pin-on-flat device, and a heavy-duty commercial wear tester. The slider material was stainless steel (AISI 440C) and the flat specimen material was an ordered alloy of Ni{sub 3}Al (IC-50). Sphere-on-flat geometry was used at ambient conditions and at normal forces ranging from 0.01 N to 100 N and average sliding velocities of 0.01 to 100.0 mm/s. The nominal, steady-state sliding friction coefficient tended to decrease with increases in normal force for each of the three tribometers, and the steady state value of sliding friction tended to increase as the mass of the machine increased. The variation of the friction force during sliding was also a characteristic of the test system. These studies provide further support to the idea that the friction of both laboratory-scale and engineering tribosystems should be treated as a parameter which may take on a range of characteristic values and not conceived as having a single, unique value for each material pair.

  17. The dryout region in frictionally heated sliding contacts

    NASA Technical Reports Server (NTRS)

    Hendricks, R. C.; Braun, J.; Arp, V.; Giarratano, P. J.

    1982-01-01

    Some conditions under which boiling and two-phase flow can occur in or near a wet sliding contact are determined and illustrated. The experimental apparatus consisted of a tool pressed against an instrumented slider plate and motion picture sequences at 4000 frames/sec. The temperature and photographic data demonstrated surface conditions of boiling, drying, trapped gas evolution (solutions), and volatility of fluid mixture components. The theoretical modeling and analysis are in reasonable agreement with experimental data.

  18. Clay-clast Aggregates: A New Textural Evidence For Seismic Fault Sliding ?

    NASA Astrophysics Data System (ADS)

    Boutareaud, S.; Fabbri, O.; Calugaru, D.; Han, R.; Shimamoto, T.

    2007-12-01

    To identify the particle dynamic processes responsible of slip-weakening in clay-rich seismic slip zones, several rotary-shear experiments were conducted at coseismic slip-rates (equivalent to 0.09, 0.9 and 1.3 m/s) at a fixed normal stress of 0.6 MPa, on a natural clay-rich gouge for saturated and for non-saturated initial conditions. The representative mechanical behavior of the simulated faults show a reproducible slip-weakening behavior, whatever initial moisture conditions. Total achieved displacements are comprised between 4 and 64 m. Detailed examination of gouge obtained at the residual friction stage in saturated and non-saturated initial conditions allows to define two types of microstructure implying two deformation regimes: a rolling regime with formation of clay-clast aggregates, and a sliding regime with formation of a foliated layer localized along the gouge-wall-rock interfaces. The observed slip-weakening behavior of simulated faults appears to be related to a decrease of the proportion of grain rolling to grain sliding with increasing slip displacement. Elevation of pore fluid pressure in the first meters of slip displacement, which represents the major contribution to the total energy budget experimentally produced, is thought to create the excess space necessary for grain rolling and subsequent formation of clay- clast aggregates. Spherical aggregates have already been reported from natural environments involving rapid slip along a seismogenic fault, landslide sole discontinuity, or sole of pyroclastic flows for which such aggregates are known to be formed by accretion of a cortex around a central spherical or ellipsoidal clast in an expanded fluidized granular flow. Therefore, the occurrence of clay-clast aggregates in natural clayey fault gouges could constitute a new potential textural evidence for thermal pressurization and consequently for past-seismic fault sliding.

  19. Shape control of distributed parameter reflectors using sliding mode control

    NASA Astrophysics Data System (ADS)

    Andoh, Fukashi; Washington, Gregory N.; Utkin, Vadim

    2001-08-01

    Sliding mode control has become one of the most powerful control methods for variable structure systems, a set of continuous systems with an appropriate switching logic. Its robustness properties and order reduction capability have made sliding mode control one of the most efficient tools for relatively higher order nonlinear plants operating under uncertain conditions. Piezo-electric materials possess the property of creating a charge when subjected to a mechanical strain, and of generating a strain when subjected to an electric field. Piezo-electric actuators are known to have a hysteresis due to the thermal motion and Coulomb interaction of Weiss domains. Because of the thermal effect the hysteresis of piezo-electric actuators is reproducible only with some uncertainty in experiments. The robustness of sliding mode control under uncertain conditions has an advantage in handling the hysteresis of piezo-electric actuators. In this research sliding mode control is used to control the shape of one- and two-dimensionally curved adaptive reflectors with piezo-electric actuators. Four discrete linear actuators for the one-dimensionally curved reflector and eight actuators for the two-dimensionally curved reflector are assumed.

  20. Tape-recorded Lectures With Slide Synchronization

    ERIC Educational Resources Information Center

    Goodhue, D.

    1969-01-01

    Describes "Taped Explanation Slide Synchronization" programs used for individual study or group showing in college zoology. Discusses preparation of programs, class organization, equipment, and costs. (EB)

  1. Development of a teledermatopathology consultation system using virtual slides

    PubMed Central

    2012-01-01

    Background An online consultation system using virtual slides (whole slide images; WSI) has been developed for pathological diagnosis, and could help compensate for the shortage of pathologists, especially in the field of dermatopathology and in other fields dealing with difficult cases. This study focused on the performance and future potential of the system. Method In our system, histological specimens on slide glasses are digitalized by a virtual slide instrument, converted into web data, and up-loaded to an open server. Using our own purpose-built online system, we then input patient details such as age, gender, affected region, clinical data, past history and other related items. We next select up to ten consultants. Finally we send an e-mail to all consultants simultaneously through a single command. The consultant receives an e-mail containing an ID and password which is used to access the open server and inspect the images and other data associated with the case. The consultant makes a diagnosis, which is sent to us along with comments. Because this was a pilot study, we also conducted several questionnaires with consultants concerning the quality of images, operability, usability, and other issues. Results We solicited consultations for 36 cases, including cases of tumor, and involving one to eight consultants in the field of dermatopathology. No problems were noted concerning the images or the functioning of the system on the sender or receiver sides. The quickest diagnosis was received only 18 minutes after sending our data. This is much faster than in conventional consultation using glass slides. There were no major problems relating to the diagnosis, although there were some minor differences of opinion between consultants. The results of questionnaires answered by many consultants confirmed the usability of this system for pathological consultation. (16 out of 23 consultants.) Conclusion We have developed a novel teledermatopathological consultation

  2. A Method to Compare the Thermal Shock Resistances and the Severity of Quenching Conditions of Brittle Solids

    NASA Astrophysics Data System (ADS)

    Osterstock, F.; Legendre, B.

    1997-03-01

    The thermal shock behavior and resistance of brittle materials are mostly investigated through the determination of a critical quenching temperature difference, Δ T_c. This technique, however, needs a large number of, almost, identical samples and is thus poorly adapted to products being in the stage of research and development. In order to overcome this difficulty, the indentation technique has been used in this work. The residual contact stresses, created during indentation, permit a stage of stable extension of the indentation cracks under the action of further stressing. The relative increase of radial crack length as a function of Vickers indentation load, c/c_0 vs. P, is taken as a criterion, or indicator, of relative thermal shock resistance, or of the severities of quenching conditions. This is validated, first in quenching materials whose empirical ranking is well established, and second in varying parameters of the Biot number. Finally, are two batches of a functional ceramic compared. The proposed criterion reflects the competition between the toughness of the quenched material, as an intrinsic property, and the thermal transient stresses, as a consequence of the physical properties of both the quenched sample and the quenching medium. Possibilities for extending the developed approach towards a more accurate description of quenching phenomena and stress states such as to refine theoretical models are discussed. La détermination d'une différence de température critique, Δ T_c, est la technique la plus souvent utilisée dans l'étude de la résistance et du comportement au choc thermique des matériaux fragiles. Elle nécessite cependant un grand nombre d'échantillons, presque identiques et est donc peu adaptée aux produits dans le stade de recherche et développement. Afin de lever cet obstacle, la méthode de l'indentation de dureté est utilisée dans ce travail. L'indentation crée des contraintes résiduelles de contact qui permettent une

  3. "Discoveries in Planetary Sciences": Slide Sets Highlighting New Advances for Astronomy Educators

    NASA Astrophysics Data System (ADS)

    Brain, David; Schneider, N.; Molaverdikhani, K.; Afsharahmadi, F.

    2012-10-01

    We present two new features of an ongoing effort to bring recent newsworthy advances in planetary science to undergraduate lecture halls. The effort, called 'Discoveries in Planetary Sciences', summarizes selected recently announced discoveries that are 'too new for textbooks' in the form of 3-slide PowerPoint presentations. The first slide describes the discovery, the second slide discusses the underlying planetary science concepts at a level appropriate for students of 'Astronomy 101', and the third presents the big picture implications of the discovery. A fourth slide includes links to associated press releases, images, and primary sources. This effort is generously sponsored by the Division for Planetary Sciences of the American Astronomical Society, and the slide sets are available at http://dps.aas.org/education/dpsdisc/ for download by undergraduate instructors or any interested party. Several new slide sets have just been released, and we summarize the topics covered. The slide sets are also being translated into languages other than English (including Spanish and Farsi), and we will provide an overview of the translation strategy and process. Finally, we will present web statistics on how many people are using the slide sets, as well as individual feedback from educators.

  4. High speed sliding of axonemal microtubules produced by outer arm dynein.

    PubMed

    Seetharam, Raviraja N; Satir, Peter

    2005-02-01

    To study dynein arm activity at high temporal resolution, axonemal sliding was measured field by field for wild type and dynein arm mutants of Tetrahymena thermophila. For wt SB255 cells, when the rate of data acquisition was 60 fps, about 5x greater than previously published observations, sliding was observed to be discontinuous with very high velocity sliding (average 196 microm/sec) for a few msec (1 or 2 fields) followed by a pause of several fields. The sliding velocities measured were an order of magnitude greater than rates previously measured by video analysis. However, when the data were analyzed at 12 fps for the same axonemes, consistent with previous observations, sliding was linear as the axonemes extended several times their original length with an average velocity of approximately 10 microm/sec. The pauses or stops occurred at approximately 200 and 300% of the initial length, suggesting that dynein arms on one axonemal doublet were initially active to the limit of extension, and then the arms on the next doublet became activated. In contrast, in a mutant where OADs are missing, sliding observed at 60 fps was continuous and slow (5 microm/sec), as opposed to the discontinuous high-velocity sliding of SB255 and of the mutant at the permissive temperature where OADs are present. High-velocity step-wise sliding was also present in axonemes from an inner arm dynein mutant (KO6). These results indicate that the high-speed discontinuous pattern of sliding is produced by the mechanochemical activity of outer arm dynein. The rate of sliding is consistent with a low duty ratio of the outer arm dynein and with the operation of each arm along a doublet once per beat.

  5. eSlide suite: an open source software system for whole slide imaging.

    PubMed

    Della Mea, V; Bortolotti, N; Beltrami, C A

    2009-08-01

    This short report briefly describes the principles underlying the telepathology technique known as whole slide imaging, and the design and implementation of a system for acquisition and visualisation of digital slides. The developed system, including an acquisition module and a visualisation module, is available as an open source on the Internet, together with sample acquired slides.

  6. Sliding Over a Phase Transition

    NASA Astrophysics Data System (ADS)

    Tosatti, Erio; Benassi, Andrea; Vanossi, Andrea; Santoro, Giuseppe E.

    2011-03-01

    The frictional response experienced by a stick-slip slider when a phase transition occurs in the underlying solid substrate is a potentially exciting, poorly explored problem. We show, based on 2-dimensional simulations modeling the sliding of a nanotip, that indeed friction may be heavily affected by a continuous structural transition. First, friction turns nonmonotonic as temperature crosses the transition, peaking at the critical temperature Tc where fluctuations are strongest. Second, below Tc friction depends upon order parameter directions, and is much larger for those where the frictional slip can cause a local flip. This may open a route towards control of atomic scale friction by switching the order parameter direction by an external field or strain, with possible application to e.g., displacive ferroelectrics such as BaTi O3 , as well as ferro- and antiferro-distortive materials. Supported by project ESF FANAS/AFRI sponsored by the Italian Research Council (CNR).

  7. On sliding of a puck

    NASA Astrophysics Data System (ADS)

    Samsonov, V. A.

    2013-09-01

    Aleksandr Yul'evich Ishlinsky liked to consider a problem with some "special thrill" at the end of the Seminar meeting of the Chair of Applied Mathematics at the Faculty of Mechanics and Mathematics at M. V. Lomonosov Moscow State University. For example, in 1978 he asked the author of this paper to describe the process of sliding of a rotating hockey puck on ice. Somewhat later, on such a seminar, the author made his report and demonstrated the experimental results, which was approved by Aleksandr Yul'evich. But the small paper on this topic, delivered to the journal "Vestnik Moskovskogo Universiteta," was published only in 1981 [1] thanks to the support of Valentin Vitalievich Rumyantsev. The author thanks the Editorial Board of this journal for the possibility of discussing one of "Ishlinsky's problems" once again.

  8. Peeling, sliding, pulling and bending

    NASA Astrophysics Data System (ADS)

    Lister, John; Peng, Gunnar

    2015-11-01

    The peeling of an elastic sheet away from thin layer of viscous fluid is a simply-stated and generic problem, that involves complex interactions between the flow and elastic deformation on a range of length scales. Consider an analogue of capillary spreading, where a blister of injected viscous fluid spreads due to tension in the overlying elastic sheet. Here the tension is coupled to the deformation of the sheet, and thus varies in time and space. A key question is whether or not viscous shear stresses ahead of the blister are sufficient to prevent the sheet sliding inwards and relieving the tension. Our asymptotic analysis reveals a dichotomy between fast and slow spreading, and between two-dimensional and axisymmetric spreading. In combination with bending stresses and gravity, which may dominate parts of the flow but not others, there is a plethora of dynamical regimes.

  9. Peeling, sliding, pulling and bending

    NASA Astrophysics Data System (ADS)

    Lister, John; Peng, Gunnar

    2016-11-01

    The peeling of an elastic sheet away from thin layer of viscous fluid is a simply-stated and generic problem, that involves complex interactions between the flow and elastic deformation on a range of length scales. Consider an analogue of capillary spreading, where a blister of injected viscous fluid spreads due to tension in the overlying elastic sheet. Here the tension is coupled to the deformation of the sheet, and thus varies in time and space. A key question is whether or not viscous shear stresses ahead of the blister are sufficient to prevent the sheet sliding inwards and relieving the tension. Our asymptotic analysis reveals a dichotomy between fast and slow spreading, and between two-dimensional and axisymmetric spreading. In combination with bending stresses and gravity, which may dominate parts of the flow but not others, there is a plethora of dynamical regimes.

  10. Experimental sliding mode control of a flexible single link manipulator

    NASA Astrophysics Data System (ADS)

    Qian, Timothy Wei Tie

    1993-09-01

    A study was conducted to explore and develop practical controller designs for a flexible manipulator based on the variable structure (VS) system and sliding mode (SM) theory. A new control design method is first proposed based on the continuous time VSSM theory, which can significantly simplify the VS system design process. Moreover, the variables concerned can be assigned separate gains. Direct application of the VSSM control system to the flexible arm, however, has limitations due to the inherent properties of the system. To solve this problem, facilitate digital implementation, and eliminate undesirable chattering in conventional VS system control, the discrete time quasi sliding mode control (DQSMC) is developed. Two control algorithms are derived satisfying the conditions for existence of discrete time sliding hypersurfaces. It is proven that the DQSMC design is equivalent to a full state feedback with its steady state motion constrained to the sliding hypersurfaces, and that DQSMC provides a general structure unifying the three different kinds of discrete time SM control. Experimental testing of the DQSMC controller showed good results, which compared favorably to the linear quadratic Gaussian controller under the same load variations. A novel approach was then devised to realize the proposed new controller designs.

  11. Modeling the Sliding/Falling Ladder Paradox

    ERIC Educational Resources Information Center

    Fox, William P.; Fox, James B.

    2003-01-01

    Recently we were presented with an interesting twist to the sliding ladder problem viewed in the related rates section of most calculus textbooks. Our problem concerning a sliding ladder that eventually hits the ground. At first, those attempting this problem fell into the calculus trap using only related rates. Previous work for this problem…

  12. Getting Clever with the Sliding Ladder

    ERIC Educational Resources Information Center

    De, Subhranil

    2014-01-01

    The familiar system involving a uniform ladder sliding against a vertical wall and a horizontal floor is considered again. The floor is taken to be smooth and the wall to be possibly rough--a situation where no matter how large the static friction coefficient between the ladder and the wall, the ladder cannot lean at rest and must slide down.…

  13. New slide test for infectious mononucleosis

    PubMed Central

    Davidson, R. J. L.

    1967-01-01

    The rapid and simple slide test for infectious mononucleosis designed by Hoff and Bauer (1965) is designed and compared with a modified sheep-cell slide screening test (Maloney and Malzone, 1949) and the differentenial absorption technique (Davidson, 1937). The claim of Hoff and Bauer that their test is more `specific' is substantiated. Brief clinical histories illustrate the argument. PMID:5628856

  14. The Cancer Digital Slide Archive - TCGA

    Cancer.gov

    Dr. David Gutman and Dr. Lee Cooper developed The Cancer Digital Slide Archive (CDSA), a web platform for accessing pathology slide images of TCGA samples. Find out how they did it and how to use the CDSA website in this Case Study.

  15. Sliding indirect hernia containing both ovaries.

    PubMed

    Fowler, Carol L

    2005-09-01

    Although sliding indirect inguinal hernias containing the ipsilateral ovary and fallopian tube are not uncommon in infant girls, sliding hernias containing both ovaries are rare. This report describes a large indirect inguinal hernia in a 1-year-old infant girl that contained the left uterine fundus, left bladder ear, as well as both ovaries and fallopian tubes.

  16. [Heritage Education Lesson Plans and Slide Presentations].

    ERIC Educational Resources Information Center

    Van Buren, Maurie

    Field tested in 27 schools and in grades four through twelve, this teaching unit stresses heritage education through the study of southern U.S. architectural styles for homes from the pioneer log structures to the 1950s ranch home. Each of the four lessons in this unit focuses around a slide presentation of 20 slides designed to fit into one…

  17. Insights from new high-resolution data from the Traenadjupet Slide on the Norwegian margin

    NASA Astrophysics Data System (ADS)

    Mozzato, Alessandro; Tappin, David; Talling, Peter; Cartigny, Matthieu; Long, David; Hunt, James; Watts, Camilla; Pope, Ed; Allin, Joshua; Stanford, Jennifer; Dowdeswell, Julian

    2015-04-01

    Submarine landslides are among the largest mass flows on Earth and can be far larger than landslides on land. They can generate tsunami and therefore represent a significant geohazard. A series of large submarine landslides have been studied previously in unusual detail along the Norwegian continental margin, including the Storegga and Traenadjupet Slides. The most closely studied is the Storegga slide(1,2) which occurred 8.2k BP and moved >3,000 km3 of sediment(2). A tsunami with run up heights sometimes reaching 20m high has been identified from deposits mapped along the Norwegian, Shetland and mainland Scottish coasts (1). The Traenadjupet Slide is the second largest slide on the Norwegian margin with a volume of about 900km3. It has been dated to ~4k BP(3,4). The volume is comparable to that of the Storegga Slide. However, no major tsunami deposit at 4ka has yet been mapped that links to the Traenadjupet Slide (Stein Bondevik, pers. comm.). The purpose of this study is to obtain new insights into how the Traenadjupet Slide was emplaced. In particular, why did movement of 900km3 of sediment during the Traenadjupet Slide fail to produce a major tsunami at 4ka? We present a new field dataset for the Traendajupet Slide including MBES bathymetry, sub-bottom profiles, and piston cores acquired during the 64PE391 research expedition in July 2014, together with data acquired previously during the JCR51 cruise. These datasets cover a large part of Traenadjupet slide and give new insights into the mechanism of the slide failure. The Traenadjupet Slide morphology is very different to that of the Storegga Slide. The Storegga Slide disintegrated generating debris flows and turbidity currents that propagated for hundreds of kilometres. The Traenadjupet Slide, on the other hand, appears not to have disintegrated in a similar manner, but rather left thick mounded deposits at the foot of the slope(5). Several distinct lobes covered with 500m-scale sediment blocks are visible

  18. Comparison of estimated core body temperature measured with the BioHarness and rectal temperature under several heat stress conditions.

    PubMed

    Seo, Yongsuk; DiLeo, Travis; Powell, Jeffrey B; Kim, Jung-Hyun; Roberge, Raymond J; Coca, Aitor

    2016-08-01

    Monitoring and measuring core body temperature is important to prevent or minimize physiological strain and cognitive dysfunction for workers such as first responders (e.g., firefighters) and military personnel. The purpose of this study is to compare estimated core body temperature (Tco-est), determined by heart rate (HR) data from a wearable chest strap physiology monitor, to standard rectal thermometry (Tre) under different conditions.  Tco-est and Tre measurements were obtained in thermoneutral and heat stress conditions (high temperature and relative humidity) during four different experiments including treadmill exercise, cycling exercise, passive heat stress, and treadmill exercise while wearing personal protective equipment (PPE).  Overall, the mean Tco-est did not differ significantly from Tre across the four conditions. During exercise at low-moderate work rates under heat stress conditions, Tco-est was consistently higher than Tre at all-time points. Tco-est underestimated temperature compared to Tre at rest in heat stress conditions and at a low work rate under heat stress while wearing PPE. The mean differences between the two measurements ranged from -0.1 ± 0.4 to 0.3 ± 0.4°C and Tco-est correlated well with HR (r = 0.795 - 0.849) and mean body temperature (r = 0.637 - 0.861).  These results indicate that, the comparison of Tco-est to Tre may result in over- or underestimation which could possibly lead to heat-related illness during monitoring in certain conditions. Modifications to the current algorithm should be considered to address such issues.

  19. Glucose level regulation via integral high-order sliding modes.

    PubMed

    Dorel, Lela

    2011-04-01

    Diabetes is a condition in which the body either does not produce enough insulin, or does not properly respond to it. This causes the glucose level in blood to increase. An algorithm based on Integral High-Order Sliding Mode technique is proposed, which keeps the normal blood glucose level automatically releasing insulin into the blood. The system is highly insensitive to inevitable parametric and model uncertainties, measurement noises and small delays.

  20. Role of kinesin-1–based microtubule sliding in Drosophila nervous system development

    PubMed Central

    Winding, Michael; Kelliher, Michael T.; Lu, Wen; Wildonger, Jill

    2016-01-01

    The plus-end microtubule (MT) motor kinesin-1 is essential for normal development, with key roles in the nervous system. Kinesin-1 drives axonal transport of membrane cargoes to fulfill the metabolic needs of neurons and maintain synapses. We have previously demonstrated that kinesin-1, in addition to its well-established role in organelle transport, can drive MT–MT sliding by transporting “cargo” MTs along “track” MTs, resulting in dramatic cell shape changes. The mechanism and physiological relevance of this MT sliding are unclear. In addition to its motor domain, kinesin-1 contains a second MT-binding site, located at the C terminus of the heavy chain. Here, we mutated this C-terminal MT-binding site such that the ability of kinesin-1 to slide MTs is significantly compromised, whereas cargo transport is unaffected. We introduced this mutation into the genomic locus of kinesin-1 heavy chain (KHC), generating the KhcmutA allele. KhcmutA neurons displayed significant MT sliding defects while maintaining normal transport of many cargoes. Using this mutant, we demonstrated that MT sliding is required for axon and dendrite outgrowth in vivo. Consistent with these results, KhcmutA flies displayed severe locomotion and viability defects. To test the role of MT sliding further, we engineered a chimeric motor that actively slides MTs but cannot transport organelles. Activation of MT sliding in KhcmutA neurons using this chimeric motor rescued axon outgrowth in cultured neurons and in vivo, firmly establishing the role of sliding in axon outgrowth. These results demonstrate that MT sliding by kinesin-1 is an essential biological phenomenon required for neuronal morphogenesis and normal nervous system development. PMID:27512046

  1. Evaluation of Resistance to Change under Different Disrupter Conditions in Children with Autism and Severe Intellectual Disability

    ERIC Educational Resources Information Center

    Lionello-DeNolf, Karen M.; Dube, William V.; McIlvane, William J.

    2010-01-01

    Translational research inspired by behavioral momentum theory in the area of developmental disabilities has shown effects in individuals over a range of functioning levels. In the current study, behavioral momentum was assessed in 6 children diagnosed with autism and severe intellectual disability. In a repeated measures design, participants were…

  2. Fatigue resistant carbon coatings for rolling/sliding contacts

    SciTech Connect

    Singh, Harpal; Ramirez, Giovanni; Eryilmaz, Osman; Greco, Aaron; Doll, Gary; Erdemir, Ali

    2016-06-01

    The growing demands for renewable energy production have recently resulted in a significant increase in wind plant installation. Field data from these plants show that wind turbines suffer from costly repair, maintenance and high failure rates. Often times the reliability issues are linked with tribological components used in wind turbine drivetrains. The primary failure modes in bearings and gears are associated with micropitting, wear, brinelling, scuffing, smearing and macropitting all of which occur at or near the surface. Accordingly, a variety of surface engineering approaches are currently being considered to alter the near surface properties of such bearings and gears to prevent these tribological failures. In the present work, we have evaluated the tribological performance of compliant highly hydrogenated diamond like carbon coating developed at Argonne National Laboratory, under mixed rolling/sliding contact conditions for wind turbine drivetrain components. The coating was deposited on AISI 52100 steel specimens using a magnetron sputter deposition system. The experiments were performed on a PCS Micro-Pitting-Rig (MPR) with four material pairs at 1.79 GPa contact stress, 40% slide to roll ratio and in polyalphaolefin (PAO4) basestock oil (to ensure extreme boundary conditions). The post-test analysis was performed using optical microscopy, surface profilometry, and Raman spectroscopy. The results obtained show a potential for these coatings in sliding/rolling contact applications as no failures were observed with coated specimens even after 100 million cycles compared to uncoated pair in which they failed after 32 million cycles, under the given test conditions.

  3. Controls on variations in MODIS fire radiative power in Alaskan boreal forests: implications for fire severity conditions

    USGS Publications Warehouse

    Barrett, Kirsten; Kasischke, Eric S.

    2013-01-01

    Fire activity in the Alaskan boreal forest, though episodic at annual and intra-annual time scales, has experienced an increase over the last several decades. Increases in burned area and fire severity are not only releasing more carbon to the atmosphere, but likely shifting vegetation composition in the region towards greater deciduous dominance and a reduction in coniferous stands. While some recent studies have addressed qualitative differences between large and small fire years in the Alaskan boreal forest, the ecological effects of a greater proportion of burning occurring during large fire years and during late season fires have not yet been examined. Some characteristics of wildfires that can be detected remotely are related to fire severity and can provide new information on spatial and temporal patterns of burning. This analysis focused on boreal wildfire intensity (fire radiative power, or FRP) contained in the Moderate Resolution Imaging Spectroradiometer (MODIS) daily active fire product from 2003 to 2010. We found that differences in FRP resulted from seasonality and intra-annual variability in fire activity levels, vegetation composition, latitudinal variation, and fire spread behavior. Our studies determined two general categories of active fire detections: new detections associated with the spread of the fire front and residual pixels in areas that had already experienced front burning. Residual pixels had a lower average FRP than front pixels, but represented a high percentage of all pixels during periods of high fire activity (large fire years, late season burning, and seasonal periods of high fire activity). As a result, the FRP from periods of high fire activity was less intense than those from periods of low fire activity. Differences related to latitude were greater than expected, with higher latitudes burning later in the season and at a higher intensity than lower latitudes. Differences in vegetation type indicate that coniferous vegetation

  4. Influence of Ni Content on Dry Sliding Wear Behavior of Sintered and Carburized Steels

    NASA Astrophysics Data System (ADS)

    Metinoz, Ibrahim; Cristofolini, Ilaria; Molinari, Alberto

    2014-10-01

    The dry sliding wear behavior of two sintered and carburized steels with different Ni amounts has been investigated. The microstructure of the two steels comprises martensite, bainite, and the Ni-rich austenite. Under the sliding conditions investigated, wear is either oxidative or adhesive. In both cases, the lower amount of the soft Ni-rich austenite results in a better wear resistance. A design procedure for parts subject to dry sliding wear applications is proposed, based on the maximum acceptable wear depth, in order to evaluate the practical significance of the differences between the two materials.

  5. Impact of Flight Enthalpy, Fuel Simulant, and Chemical Reactions on the Mixing Characteristics of Several Injectors at Hypervelocity Flow Conditions

    NASA Technical Reports Server (NTRS)

    Drozda, Tomasz G.; Baurle, Robert A.; Drummond, J. Philip

    2016-01-01

    The high total temperatures or total enthalpies required to duplicate the high-speed flight conditions in ground experiments often place stringent requirements on the material selection and cooling needs for the test articles and intrusive flow diagnostic equipment. Furthermore, for internal flows, these conditions often complicate the use of nonintrusive diagnostics that need optical access to the test section and interior portions of the flowpath. Because of the technical challenges and increased costs associated with experimentation at high values of total enthalpy, an attempt is often made to reduce it. This is the case for the Enhanced Injection and Mixing Project (EIMP) currently underway in the Arc-Heated Scramjet Test Facility at the NASA Langley Research Center. The EIMP aims to investigate supersonic combustion ramjet (scramjet) fuel injection and mixing physics, improve the understanding of underlying physical processes, and develop enhancement strategies and functional relationships between mixing performance and losses relevant to flight Mach numbers greater than 8. The experiments will consider a "direct-connect" approach and utilize a Mach 6 nozzle to simulate the combustor entrance flow of a scramjet engine. However, while the value of the Mach number is matched to that expected at the combustor entrance in flight, the maximum value of the total enthalpy for these experiments is limited by the thermal-structural limits of the uncooled experimental hardware. Furthermore, the fuel simulant is helium, not hydrogen. The use of "cold" flows and non-reacting mixtures of fuel simulants for mixing experiments is not new and has been extensively utilized as a screening technique for scramjet fuel injectors. In this study, Reynolds-averaged simulations are utilized (RAS) to systematically verify the implicit assumptions used by the EIMP. This is accomplished by first performing RAS of mixing for two injector configurations at planned nominal experimental

  6. Total lymphoid irradiation and cyclophosphamide conditioning prior to bone marrow transplantation for patients with severe aplastic anemia

    SciTech Connect

    Ramsay, N.K.; Kim, T.H.; McGlave, P.; Goldman, A.; Nesbit, M.E. Jr.; Krivit, W.; Woods, W.G.; Kersey, J.H.

    1983-09-01

    A preparative regimen, consisting of total lymphoid irradiation and cyclophosphamide, was utilized in 40 patients with severe aplastic anemia undergoing allogeneic marrow transplantation. This regimen was successful in decreasing rejection in these previously transfused patients, as only one patient rejected the marrow graft. Twenty-nine of the 40 transplanted patients are surviving from 1.5 to 59 mo, with a median follow-up of 24 mo. The actuarial survival rate for these heavily transfused patients with aplastic anemia is 72% at 2 yr. This preparative regimen is extremely effective in decreasing rejection following transplantation for severe aplastic anemia. Future efforts in this area must be aimed at the elimination of graft-versus-host disease and control of fatal infections.

  7. VICTORIA: A mechanistic model of radionuclide behavior in the reactor coolant system under severe accident conditions. Revision 1

    SciTech Connect

    Heams, T J; Williams, D A; Johns, N A; Mason, A; Bixler, N E; Grimley, A J; Wheatley, C J; Dickson, L W; Osborn-Lee, I; Domagala, P; Zawadzki, S; Rest, J; Alexander, C A; Lee, R Y

    1992-12-01

    The VICTORIA model of radionuclide behavior in the reactor coolant system (RCS) of a light water reactor during a severe accident is described. It has been developed by the USNRC to define the radionuclide phenomena and processes that must be considered in systems-level models used for integrated analyses of severe accident source terms. The VICTORIA code, based upon this model, predicts fission product release from the fuel, chemical reactions involving fission products, vapor and aerosol behavior, and fission product decay heating. Also included is a detailed description of how the model is implemented in VICTORIA, the numerical algorithms used, and the correlations and thermochemical data necessary for determining a solution. A description of the code structure, input and output, and a sample problem are provided.

  8. Lost opportunities for effective management of obstetric conditions to reduce maternal mortality and severe maternal morbidity in Argentina and Uruguay

    PubMed Central

    Karolinski, Ariel; Mazzoni, Agustina; Belizán, José M; Althabe, Fernando; Bergel, Eduardo; Buekens, Pierre

    2010-01-01

    Objective To review the use of evidence-based practices in the care of mothers who died or had severe morbidity attending public hospitals in two Latin American countries. Methods This study is part of a multicenter intervention to increase the use of evidence-based obstetric practice. Data on maternal deaths and women admitted to intensive care units whose deliveries occurred in 24 hospitals in Argentina and Uruguay were analyzed. Primary outcomes were use rates of effective interventions to reduce maternal mortality (MM) and severe maternal morbidity (SMM). Results A total of 106 women were included: 26 maternal deaths and 80 women with SMM. Some effective interventions for severe acute hemorrhage had a high use rate, such as blood transfusion (91%) and timely cesarean delivery (75%), while active management of the third stage of labor (25%) showed a lower rate. The overall use rate of effective interventions was 58% (95% CI, 49%–67%). This implies that 42% of the women did not receive one of the effective interventions to reduce MM and SMM. Conclusion This study shows a low use of effective interventions to reduce MM and SMM in public hospitals in Argentina and Uruguay. Dissemination and implementation of evidence-based practices must be guaranteed to effectively achieve progress on maternal health. PMID:20605151

  9. An updated nuclear criticality slide rule

    SciTech Connect

    Hopper, C.M.; Broadhead, B.L.

    1998-04-01

    This Volume 2 contains the functional version of the updated nuclear criticality slide rule (more accurately, sliding graphs) that is referenced in An Updated Nuclear Criticality Slide Rule: Technical Basis, NUREG/CR-6504, Vol. 1 (ORNL/TM-13322/V1). This functional slide rule provides a readily usable {open_quotes}in-hand{close_quotes} method for estimating pertinent nuclear criticality accident information from sliding graphs, thereby permitting (1) the rapid estimation of pertinent criticality accident information without laborious or sophisticated calculations in a nuclear criticality emergency situation, (2) the appraisal of potential fission yields and external personnel radiation exposures for facility safety analyses, and (3) a technical basis for emergency preparedness and training programs at nonreactor nuclear facilities. The slide rule permits the estimation of neutron and gamma dose rates and integrated doses based upon estimated fission yields, distance from the fission source, and time-after criticality accidents for five different critical systems. Another sliding graph permits the estimation of critical solution fission yields based upon fissile material concentration, critical vessel geometry, and solution addition rate. Another graph provides neutron and gamma dose-reduction factors for water, steel, and concrete. Graphs from historic documents are provided as references for estimating critical parameters of various fissile material systems. Conversion factors for various English and metric units are provided for quick reference.

  10. Whole slide imaging for educational purposes.

    PubMed

    Pantanowitz, Liron; Szymas, Janusz; Yagi, Yukako; Wilbur, David

    2012-01-01

    Digitized slides produced by whole slide image scanners can be easily shared over a network or by transferring image files to optical or other data storage devices. Navigation of digitized slides is interactive and intended to simulate viewing glass slides with a microscope (virtual microscopy). Image viewing software permits users to edit, annotate, analyze, and easily share whole slide images (WSI). As a result, WSI have begun to replace the traditional light microscope, offering a myriad of opportunities for education. This article focuses on current applications of WSI in education and proficiency testing. WSI has been successfully explored for graduate education (medical, dental, and veterinary schools), training of pathology residents, as an educational tool in allied pathology schools (e.g., cytotechnology), for virtual tracking and tutoring, tele-education (tele-conferencing), e-learning, virtual workshops, at tumor boards, with interactive publications, and on examinations. WSI supports flexible and cost-effective distant learning and augments problem-oriented teaching, competency evaluation, and proficiency testing. WSI viewed on touchscreen displays and with tablet technology are especially beneficial for education. Further investigation is necessary to develop superior WSI applications that better support education and to design viewing stations with ergonomic tools that improve the WSI-human interface and navigation of virtual slides. Studies to determine the impact of training pathologists without exposure to actual glass slides are also needed.

  11. Severe Weather

    ERIC Educational Resources Information Center

    Forde, Evan B.

    2004-01-01

    Educating the public about safety issues related to severe weather is part of the National Oceanic and Atmospheric Administration's (NOAA) mission. This month's insert, Severe Weather, has been created by NOAA to help educate the public about hazardous weather conditions. The four types of severe weather highlighted in this poster are hurricanes,…

  12. Severe Weather

    ERIC Educational Resources Information Center

    Forde, Evan B.

    2004-01-01

    Educating the public about safety issues related to severe weather is part of the National Oceanic and Atmospheric Administration's (NOAA) mission. This article deals with a poster entitled, "Severe Weather," that has been created by NOAA to help educate the public about hazardous weather conditions. The four types of severe weather highlighted in…

  13. The Earth surface slide movement at Soledad

    NASA Astrophysics Data System (ADS)

    Moreno, A.

    1986-11-01

    The Earth surface slide movement at Soledad is a mountain-slide type of movement. Estimations of the thickness of the layer which is moving range between 10 and 100 m. There is no proof that the movement is water induced, but it could be influenced by the water household. The slope of the slide area is H: D = 1: 2. The height difference in the moving area studied, according to this paper, is 1 km. The actual rate of movement is about 12 cm/yr.

  14. Argon bubble behavior in slide-gate tundish nozzles during continuous casting of steel slabs

    NASA Astrophysics Data System (ADS)

    Bai, Hua

    2000-10-01

    Argon injection into a tundish nozzle is an efficient and widely employed method to reduce nozzle clogging in the continuous casting process. It also affects casting operation and product quality by changing the flow pattern in the nozzle and mold. The current work combines mathematical modeling and experiments to investigate the argon bubble behavior in slide-gate nozzles and to analyze phenomena related to product defects and operational problems during the continuous casting of steel slabs. Water model experiments are performed to study bubble formation behavior, including bubble size, frequency, mode and effects of variables such as liquid velocity, gas injection flow rate, gas injection hole size and gas density. An analytical model is developed to predict the average bubble size. Argon gas bubbles are predicted to be 1--5mm. This is larger than air bubbles in water, especially at low speed. A three-dimensional finite difference model is developed to study the turbulent flow of liquid steel and argon bubble in the slide-gate nozzles. Experiments are performed on a 0.4-scale "water caster" to verify the model by comparing the model prediction with the measurements using PIV (Particle Image Velocimetry) technology. A weighted average scheme for the overall outflow is developed to quantify jet characteristics such as jet angle, jet speed, back flow zone fraction, turbulence and biased mass flow. Swirl is generated at nozzle ports. The validated model is employed to perform extensive parametric studies to investigate the effects of casting operation conditions such as gas injection, slide-gate orientation, casting speed, gate opening and bubble size and nozzle port design including port angle and port shape. The interrelated effects of nozzle clogging, argon injection, tundish bath depth, slide gate opening and nozzle bore diameter on the flow rate and pressure in tundish nozzles are quantified using an inverse model, based on interpolation of the numerical

  15. [Prevalence and severity of gingivitis among scholars (7-14 years): local conditions associated to bleeding on probing].

    PubMed

    Chambrone, Leandro; Macedo, Sergio Bassit; Ramalho, Francisco Cardoso; Trevizani Filho, Eduardo; Chambrone, Luiz Armando

    2010-03-01

    The objective of this study was to collect data about the prevalence and severity of gingivitis in a sample of scholars, as well as its relationship with possible local risk factors. Two hundred and six subjects were examined, 107 male and 99 female, with age ranging from 7 to 14 years, where data from their Plaque Index (IP), Gingival Index (IG), and Clinical Probing Depth (PCS) were collected. Among all the clinical parameters observed, the mean values found referent to PCS, IP and IG were 1.58 + 0.46, 1.12 + 0.49 and 0.89 + 0.32, respectively. Ninety five subjects (46.1%) presented a diagnostic of slight gingivitis and 111 (53.9%) of moderate gingivitis. Overall, male subjects presented statistically more dental plaque and more gingival inflammation than female subjects. Clinical signs of gingival inflammation were found in all the examined subjects. Gingivitis severity around permanent teeth was directly linked to the amount of dental plaque deposits and to the presence of bleeding on probing.

  16. Swarm slide - debris flow disaster induced by extreme rainfall in Hiroshima, August 2014 and lessons learnt in urban designing

    NASA Astrophysics Data System (ADS)

    Fukuoka, H.; Wang, C.

    2015-12-01

    Hiroshima city was hit by swarm debris flows along a narrow, and linear-shaped rain band of 2 km x 10 km which appeared in the early morning of August 20, 2014. Most of the flows were induced by shallow slide in the upstream. This disaster claimed 74 death, although this city experienced very similar disaster in 1999, claiming more than 30 residents lives. In the most severely affected debris flow torrent, more than 50 residents were killed. Most of the casualties arose in the wooden, vulnerable houses constructed in front of the exit of torrents. Points and lessons learnt from the disaster are as follows:1. Authors collected two types of sands from the source scar of the initial debris slides which induced debris flows. Tested by the ring shear apparatus under pore-pressure control condition, clear "Sliding surface liquefaction" was confirmed for both samples even under small normal stress, representing the small thickness of the slides. These results shows even instant excess pore pressure could initiate the slides and trigger slide-induced debris flow byundrained loading onto the torrent deposits.2. Apparently long-term land-use change since 1945 affected and raised the vulnerability of the community. Residential area had expanded into hill-slope (mountainous / semi-mountainous area) especially along the torrents. Those communities were developed on the past debris flow fan.3. As the devastated area is very close to downtown of Hiroshima city, it gave large societal impact to the Japanese citizens. After 1999 Hiroshima debris flow disaster, the Landslide disaster reduction law which intends to promote designation of landslide potential risk zones, was adopted in 2000. Immediately after 2014 disaster, national diet approved revision of the bill to promote rapid completion of the designation over the national territory. MLIT (Ministry of Land, Infrastructure, Tranportation and Tourism) decided to install X-band rain radars at more sites to cover whole city zones

  17. Tribology of Si/SiO2 in humid air: transition from severe chemical wear to wearless behavior at nanoscale.

    PubMed

    Chen, Lei; He, Hongtu; Wang, Xiaodong; Kim, Seong H; Qian, Linmao

    2015-01-13

    Wear at sliding interfaces of silicon is a main cause for material loss in nanomanufacturing and device failure in microelectromechanical system (MEMS) applications. However, a comprehensive understanding of the nanoscale wear mechanisms of silicon in ambient conditions is still lacking. Here, we report the chemical wear of single crystalline silicon, a material used for micro/nanoscale devices, in humid air under the contact pressure lower than the material hardness. A transmission electron microscopy (TEM) analysis of the wear track confirmed that the wear of silicon in humid conditions originates from surface reactions without significant subsurface damages such as plastic deformation or fracture. When rubbed with a SiO2 ball, the single crystalline silicon surface exhibited transitions from severe wear in intermediate humidity to nearly wearless states at two opposite extremes: (a) low humidity and high sliding speed conditions and (b) high humidity and low speed conditions. These transitions suggested that at the sliding interfaces of Si/SiO2 at least two different tribochemical reactions play important roles. One would be the formation of a strong "hydrogen bonding bridge" between hydroxyl groups of two sliding interfaces and the other the removal of hydroxyl groups from the SiO2 surface. The experimental data indicated that the dominance of each reaction varies with the ambient humidity and sliding speed.

  18. Evaluation of immunohistochemical staining using whole-slide imaging for HER2 scoring of breast cancer in comparison with real glass slides.

    PubMed

    Kondo, Yuzuru; Iijima, Tatsuo; Noguchi, Masayuki

    2012-09-01

    Whole-slide imaging (WSI) has been used for education and histological image preservation, and several studies have also reported its validity for practical pathological diagnosis. However, such studies employed materials stained with hematoxylin-eosin (HE), and very few attempts have been made to use immunohistochemically stained materials for diagnostic purposes. In the present study, we investigated the availability of WSI diagnosis for immunohistochemically stained materials in place of routine glass slides. Thirty pathologists participated in a trial of HER2 expression diagnosis using WSI and compared the results with those obtained by light microscopy. The validity of WSI diagnosis (interobserver agreement) was rated as 'substantial' in comparison with glass slide diagnosis (κ-value = 0.719). There was a tendency for observers to assign higher scores with WSI than with glass slides, probably because WSI requires slides to be scanned into a computer and observed via a monitor. Although we were able to demonstrate the potential utility of WSI for diagnosing immunostained materials, it must be borne in mind that there are some differences in visualization between WSI and glass slides.

  19. Automated robust registration of grossly misregistered whole-slide images with varying stains

    NASA Astrophysics Data System (ADS)

    Litjens, G.; Safferling, K.; Grabe, N.

    2016-03-01

    Cancer diagnosis and pharmaceutical research increasingly depend on the accurate quantification of cancer biomarkers. Identification of biomarkers is usually performed through immunohistochemical staining of cancer sections on glass slides. However, combination of multiple biomarkers from a wide variety of immunohistochemically stained slides is a tedious process in traditional histopathology due to the switching of glass slides and re-identification of regions of interest by pathologists. Digital pathology now allows us to apply image registration algorithms to digitized whole-slides to align the differing immunohistochemical stains automatically. However, registration algorithms need to be robust to changes in color due to differing stains and severe changes in tissue content between slides. In this work we developed a robust registration methodology to allow for fast coarse alignment of multiple immunohistochemical stains to the base hematyoxylin and eosin stained image. We applied HSD color model conversion to obtain a less stain color dependent representation of the whole-slide images. Subsequently, optical density thresholding and connected component analysis were used to identify the relevant regions for registration. Template matching using normalized mutual information was applied to provide initial translation and rotation parameters, after which a cost function-driven affine registration was performed. The algorithm was validated using 40 slides from 10 prostate cancer patients, with landmark registration error as a metric. Median landmark registration error was around 180 microns, which indicates performance is adequate for practical application. None of the registrations failed, indicating the robustness of the algorithm.

  20. Were the Trænadjupet and Nyk Slides multi-staged?

    NASA Astrophysics Data System (ADS)

    Allin, Joshua; Mozzato, Alessandro; Tappin, David; Talling, Peter; Hunt, James

    2016-04-01

    Submarine landslides originating from active and extinct trough mouth fans are some of the largest single mass movements evident on Earth. These landslides are capable of damaging offshore infrastructure and can also trigger far-reaching tsunamis. For these reasons understanding the timing, dynamics, and triggering mechanisms of large submarine landslides is important for regional geohazard assessment. The Trænadjupet Slide occurred 4,000 ca. years ago and originated from the Trænadjupet paleo-ice stream on the Central Norwegian margin. The Trænadjupet Slide partially buried the deposits of a previous slide originating from the same section of the Norwegian margin; the Nyk Slide, which occurred at 16,000 ca years ago. Although the Trænadjupet Slide had an estimated volume of 900 km3 and originated from a shallow water depth, it does not appear to have triggered a tsunami. This is in contrast to the comparably-sized Storegga Slide, which produced a tsunami that devastated coastal areas as far away as Scotland. The apparent absence of a tsunami suggests that the failure dynamics for the Trænadjupet slide were different to that of other large slides along the Norwegian Margin. The deposits of both the Trænadjupet and Nyk Slides consist of several blocky lobes extending out into the Lofoten Basin. The lobate morphology of the deposits may imply that both slides occurred in a number of different and possibly temporally-disparate stages. Importantly, multi-staged failures have a much lower tsunamigenic potential due to the lower initial volume displacement. These staggered failures consisting of smaller sediment volumes might explain why no contemporaneous onshore tsunami deposits are found on nearby coastlines, particularly in the case of the post-glacial Trænadjupet Slide. Here we present a new sediment core dataset collected from the previously un-sampled lobes of the Trænadjupet and Nyk Slides. These cores will help us better characterise the deposit types

  1. Comparative study of the in vitro protective effects of several antioxidants on elongation factor 2 under oxidative stress conditions.

    PubMed

    Arguelles, Sandro; Cano, Mercedes; Machado, Alberto; Ayala, Antonio

    2010-01-01

    One of the biochemical pathways affected by aging in all organisms is protein synthesis. Previous reports from our laboratory have indicated that the elongation step is specially affected by aging as a consequence of alterations in elongation factor-2 (eEF-2). In the present work, we studied in vitro the effectiveness of several individual nutritional antioxidants in protecting the levels of hepatic eEF-2 subjected to oxidative stress induced by cumene hydroperoxide. The in vitro system employed consisted of rat liver homogenates treated with cumene hydroperoxide. The antioxidants used in this study were lipoic acid, coenzyme Q10, tethrahydrofolic acid, and N-tert-butyl-alpha-phenylnitrone. The results indicate that the antioxidants have different capacities to prevent eEF-2 loss, folic acid being the most effective. A comparison between the antioxidants used and their potential pro-oxidant activity is also discussed, on the basis of the oxidative stress parameters measured.

  2. Traction forces at solid-lubricated rolling/sliding contacts

    NASA Technical Reports Server (NTRS)

    Aggarwal, B. B.; Bovenkerk, R. L.

    1985-01-01

    A single-element traction rig was used to measure the traction forces at a solid-lubricated contact of a ball against a flat disk at room temperature under combine rolling and sliding. The load and speed conditions were selected to match those anticipated for bearing applications in adiabatic diesel engines. Traction vs slide/roll ratio curves were similar to those for liquid lubricants but the traction forces were an order of magnitude higher. The test data were used to derive equations to predict traction force as a function of contact stress and rolling speed. The data showed that the magnitude of traction forces were almost the same for all the lubricants tested. The lubricants, should, therefore, be selected on the basis of their ability to limit the wear of contact surfaces.

  3. A trial of plerixafor adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe combined immunodeficiency.

    PubMed

    Dvorak, Christopher C; Horn, Biljana N; Puck, Jennifer M; Czechowicz, Agnieszka; Shizuru, Judy A; Ko, Rose M; Cowan, Morton J

    2014-09-01

    For infants with SCID, the ideal conditioning regimen before allogeneic HCT would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with G-CSF plus plerixafor given to the host to mobilize HSC from their niches. We enrolled six patients who received CD34-selected haploidentical cells and one who received T-replete matched unrelated BM. All patients receiving G-CSF and plerixafor had generally poor CD34(+) cell and Lin(-) CD34(+) CD38(-) CD90(+) CD45RA(-) HSC mobilization, and developed donor T cells, but no donor myeloid or B-cell engraftment. Although well tolerated, G-CSF plus plerixafor alone failed to overcome physical barriers to donor engraftment.

  4. A trial of alemtuzumab adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe combined immunodeficiency.

    PubMed

    Dvorak, Christopher C; Horn, Biljana N; Puck, Jennifer M; Adams, Stuart; Veys, Paul; Czechowicz, Agnieszka; Cowan, Morton J

    2014-09-01

    For infants with SCID the ideal conditioning regimen before allogeneic HCT would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with alemtuzumab monotherapy to overcome NK-cell mediated immunologic barriers to engraftment. We enrolled four patients who received CD34-selected haploidentical cells, two of whom failed to engraft donor T cells. The two patients who engrafted had delayed T-cell reconstitution, despite rapid clearance of circulating alemtuzumab. Although well-tolerated, alemtuzumab failed to overcome immunologic barriers to donor engraftment. Furthermore, alemtuzumab may slow T-cell development in patients with SCID in the setting of a T-cell depleted graft.

  5. Automated single-slide staining system

    NASA Technical Reports Server (NTRS)

    Mills, S. M.; Wilkins, J. R.

    1974-01-01

    Apparatus developed to Gram-stain single slides automatically is flexible enough to accommodate other types of staining procedures. Method frees operator and eliminates necessity for subjective evaluations as to length of staining or decolorizing time.

  6. Projector slides - preparation, construction and use.

    PubMed

    Galer, I A

    1976-12-01

    Projector slides are used widely as visual aids in lectures and meetings. However, they are often difficult to read and to interpret, and can bring about more confusion than illumination to an audience. A framework is offered for the non-specialist in graphic design, within which the preparation, construction and presentation of projector slides may be placed in a systematic fashion. Summary recommendations are also given.

  7. Laboratory insights into the chemical and kinetic evolution of several organic molecules under simulated Mars surface UV radiation conditions

    NASA Astrophysics Data System (ADS)

    Poch, O.; Kaci, S.; Stalport, F.; Szopa, C.; Coll, P.

    2014-11-01

    The search for organic carbon at the surface of Mars, as clues of past habitability or remnants of life, is a major science goal of Mars' exploration. Understanding the chemical evolution of organic molecules under current martian environmental conditions is essential to support the analyses performed in situ. What molecule can be preserved? What is the timescale of organic evolution at the surface? This paper presents the results of laboratory investigations dedicated to monitor the evolution of organic molecules when submitted to simulated Mars surface ultraviolet radiation (190-400 nm), mean temperature (218 ± 2 K) and pressure (6 ± 1 mbar) conditions. Experiments are done with the MOMIE simulation setup (for Mars Organic Molecules Irradiation and Evolution) allowing both a qualitative and quantitative characterization of the evolution the tested molecules undergo (Poch, O. et al. [2013]. Planet. Space Sci. 85, 188-197). The chemical structures of the solid products and the kinetic parameters of the photoreaction (photolysis rate, half-life and quantum efficiency of photodecomposition) are determined for glycine, urea, adenine and chrysene. Mellitic trianhydride is also studied in order to complete a previous study done with mellitic acid (Stalport, F., Coll, P., Szopa, C., Raulin, F. [2009]. Astrobiology 9, 543-549), by studying the evolution of mellitic trianhydride. The results show that solid layers of the studied molecules have half-lives of 10-103 h at the surface of Mars, when exposed directly to martian UV radiation. However, organic layers having aromatic moieties and reactive chemical groups, as adenine and mellitic acid, lead to the formation of photoresistant solid residues, probably of macromolecular nature, which could exhibit a longer photostability. Such solid organic layers are found in micrometeorites or could have been formed endogenously on Mars. Finally, the quantum efficiencies of photodecomposition at wavelengths from 200 to 250 nm

  8. [Effects of several exorphins and endorphins on the escape reaction of the cockroach Periplaneta americana under elevated temperature conditions].

    PubMed

    Gritsaĭ, O B; Dubynin, V A; Bespalova, Zh D; Pilipenko, V E

    2009-01-01

    The ability of several alimentary opioid peptides (exorphin C, rubiscolin-5, cytochrophi-4) and endorphins (met-enkephalin, dynotphin A(1-10), beta-neoendorphin) to change the escape reaction of the cockroaches Periplaneta americana at their placement into a hot chamber was studied. The ED50 values increasing twice the insect stay time in the hot chamber as well as duration and dynamics of the effects were determined. It has been shown that ED5 decreases statistically significantly with increase of the length of the peptide molecule and its affinity of duration of the effects and to an increase of their affinity to delta-receptors - to prolongation of the reaction (more than150 min). In the group of alimentary peptides (exorphins) the most active was a fragment of D-ribulose-1,5-biphosphate carboxylase/oxigenase rubiscolin-5 (ED5 = 386 nM per individual). This might indicate a specific ability of some plant proteins to regulate (decrease) the insect protective behavior.

  9. Risk Analysis for Unintentional Slide Deployment During Airline Operations.

    PubMed

    Ayra, Eduardo S; Insua, David Ríos; Castellanos, María Eugenia; Larbi, Lydia

    2015-09-01

    We present a risk analysis undertaken to mitigate problems in relation to the unintended deployment of slides under normal operations within a commercial airline. This type of incident entails relevant costs for the airline industry. After assessing the likelihood and severity of its consequences, we conclude that such risks need to be managed. We then evaluate the effectiveness of various countermeasures, describing and justifying the chosen ones. We also discuss several issues faced when implementing and communicating the proposed measures, thus fully illustrating the risk analysis process.

  10. Preparing Scientific Papers, Posters, and Slides.

    PubMed

    Lefor, Alan Kawarai; Maeno, Misato

    2016-01-01

    Publications and presentations are important in academic medicine. The ability to present information in a standard fashion is critically important. Papers, posters, and slides must be prepared appropriately to maximize their chance of being accepted. The first step is to use word processing software correctly. English language usage must conform to standard scientific English usage. Abbreviations should be avoided as much as possible. Numerical data must be presented with the appropriate number of significant figures. The first step in preparing a paper is to decide the target journal. Papers should always be written in 12 point Times New Roman font, while slides and posters should be in Arial or Helvetica. The Results section must contain actual data with appropriate statistical analysis. Take great care to prepare figures and tables according to the journal's instructions. Posters must be prepared to allow easy reading at a distance of 2m. Use a white background and dark letters. The majority of the area of your poster should be Results, and there is no need to include the abstract or references on a poster. Slide presentations should be limited to about one slide for each minute of the talk. Avoid the use of animations and excessive use of color. Do not use abbreviations on slides. Following these simple guidelines will meet the requirements of most journals and allow your audience to appreciate the data on your posters and slides.

  11. Compact, Automated Centrifugal Slide-Staining System

    NASA Technical Reports Server (NTRS)

    Feeback, Daniel L.; Clarke, Mark S. F.

    2004-01-01

    The Directional Acceleration Vector-Driven Displacement of Fluids (DAVD-DOF) system, under development at the time of reporting the information for this article, would be a relatively compact, automated, centrifugally actuated system for staining blood smears and other microbiological samples on glass microscope slides in either a microgravitational or a normal Earth gravitational environment. The DAVD-DOF concept is a successor to the centrifuge-operated slide stainer (COSS) concept, which was reported in Slide-Staining System for Microgravity or Gravity (MSC-22949), NASA Tech Briefs, Vol. 25, No. 1 (January, 2001), page 64. The COSS includes reservoirs and a staining chamber that contains a microscope slide to which a biological sample is affixed. The staining chamber is sequentially filled with and drained of staining and related liquids from the reservoirs by use of a weighted plunger to force liquid from one reservoir to another at a constant level of hypergravity maintained in a standard swing-bucket centrifuge. In the DAVD-DOF system, a staining chamber containing a sample would also be sequentially filled and emptied, but with important differences. Instead of a simple microscope slide, one would use a special microscope slide on which would be fabricated a network of very small reservoirs and narrow channels connected to a staining chamber (see figure). Unlike in the COSS, displacement of liquid would be effected by use of the weight of the liquid itself, rather than the weight of a plunger.

  12. Tribology of the lubricant quantized sliding state.

    PubMed

    Castelli, Ivano Eligio; Capozza, Rosario; Vanossi, Andrea; Santoro, Giuseppe E; Manini, Nicola; Tosatti, Erio

    2009-11-07

    In the framework of Langevin dynamics, we demonstrate clear evidence of the peculiar quantized sliding state, previously found in a simple one-dimensional boundary lubricated model [A. Vanossi et al., Phys. Rev. Lett. 97, 056101 (2006)], for a substantially less idealized two-dimensional description of a confined multilayer solid lubricant under shear. This dynamical state, marked by a nontrivial "quantized" ratio of the averaged lubricant center-of-mass velocity to the externally imposed sliding speed, is recovered, and shown to be robust against the effects of thermal fluctuations, quenched disorder in the confining substrates, and over a wide range of loading forces. The lubricant softness, setting the width of the propagating solitonic structures, is found to play a major role in promoting in-registry commensurate regions beneficial to this quantized sliding. By evaluating the force instantaneously exerted on the top plate, we find that this quantized sliding represents a dynamical "pinned" state, characterized by significantly low values of the kinetic friction. While the quantized sliding occurs due to solitons being driven gently, the transition to ordinary unpinned sliding regimes can involve lubricant melting due to large shear-induced Joule heating, for example at large speed.

  13. WTP Pretreatment Facility Potential Design Deficiencies--Sliding Bed and Sliding Bed Erosion Assessment

    SciTech Connect

    Hansen, E. K.

    2015-05-06

    This assessment is based on readily available literature and discusses both Newtonian and non-Newtonian slurries with respect to sliding beds and erosion due to sliding beds. This report does not quantify the size of the sliding beds or erosion rates due to sliding beds, but only assesses if they could be present. This assessment addresses process pipelines in the Pretreatment (PT) facility and the high level waste (HLW) transfer lines leaving the PT facility to the HLW vitrification facility concentrate receipt vessel.

  14. The Reconstruction of the pre Storegga Slide Seafloor and Stratigraphy Using a Dense Grid of 2D Seismic Records.

    NASA Astrophysics Data System (ADS)

    Forsberg, C. F. M.

    2014-12-01

    This work was performed as part of the Storegga Slide study that was part of the Ormen Lange Gas Field development on the Mid Norwegian continental margin. The purpose of the reconstruction was to use seismic reflection data as a basis to provide slide volume estimates, pre slide stratigraphy and seafloor morphology that could be used as input to separate conceptual and numerical slide models. A comprehensive database of 2D high resolution and 2D exploration seismic reflection profiles was used. Additionally, the seismic stratigraphy on both sides of the Storegga Slide scar was well known, but had to be applied/interpreted on most of the seismic sections in the database to provide geographical grids of the horizon depths. The reconstruction was performed by "filling" The Storegga Slide scar from bottom up through interpolation and gridding of the thicknesses of successively younger units removed by the slide. The estimated volume of the slide was 3500 km3 with a maximum removal of 500 m of overburden. The loss of overburden due sliding estimated from the reconstructon was confirmed at several sites where geotechnical boreholes had been drilled.

  15. Virtual slides in peer reviewed, open access medical publication

    PubMed Central

    2011-01-01

    Background Application of virtual slides (VS), the digitalization of complete glass slides, is in its infancy to be implemented in routine diagnostic surgical pathology and to issues that are related to tissue-based diagnosis, such as education and scientific publication. Approach Electronic publication in Pathology offers new features of scientific communication in pathology that cannot be obtained by conventional paper based journals. Most of these features are based upon completely open or partly directed interaction between the reader and the system that distributes the article. One of these interactions can be applied to microscopic images allowing the reader to navigate and magnify the presented images. VS and interactive Virtual Microscopy (VM) are a tool to increase the scientific value of microscopic images. Technology and Performance The open access journal Diagnostic Pathology http://www.diagnosticpathology.org has existed for about five years. It is a peer reviewed journal that publishes all types of scientific contributions, including original scientific work, case reports and review articles. In addition to digitized still images the authors of appropriate articles are requested to submit the underlying glass slides to an institution (DiagnomX.eu, and Leica.com) for digitalization and documentation. The images are stored in a separate image data bank which is adequately linked to the article. The normal review process is not involved. Both processes (peer review and VS acquisition) are performed contemporaneously in order to minimize a potential publication delay. VS are not provided with a DOI index (digital object identifier). The first articles that include VS were published in March 2011. Results and Perspectives Several logistic constraints had to be overcome until the first articles including VS could be published. Step by step an automated acquisition and distribution system had to be implemented to the corresponding article. The acceptance of

  16. Effect of nontronite smectite clay on the chemical evolution of several organic molecules under simulated martian surface ultraviolet radiation conditions.

    PubMed

    Poch, Olivier; Jaber, Maguy; Stalport, Fabien; Nowak, Sophie; Georgelin, Thomas; Lambert, Jean-François; Szopa, Cyril; Coll, Patrice

    2015-03-01

    Most of the phyllosilicates detected at the surface of Mars today are probably remnants of ancient environments that sustained long-term bodies of liquid water at the surface or subsurface and were possibly favorable for the emergence of life. Consequently, phyllosilicates have become the main mineral target in the search for organics on Mars. But are phyllosilicates efficient at preserving organic molecules under current environmental conditions at the surface of Mars? We monitored the qualitative and quantitative evolutions of glycine, urea, and adenine in interaction with the Fe(3+)-smectite clay nontronite, one of the most abundant phyllosilicates present at the surface of Mars, under simulated martian surface ultraviolet light (190-400 nm), mean temperature (218 ± 2 K), and pressure (6 ± 1 mbar) in a laboratory simulation setup. We tested organic-rich samples that were representative of the evaporation of a small, warm pond of liquid water containing a high concentration of organics. For each molecule, we observed how the nontronite influences its quantum efficiency of photodecomposition and the nature of its solid evolution products. The results reveal a pronounced photoprotective effect of nontronite on the evolution of glycine and adenine; their efficiencies of photodecomposition were reduced by a factor of 5 when mixed at a concentration of 2.6 × 10(-2) mol of molecules per gram of nontronite. Moreover, when the amount of nontronite in the sample of glycine was increased by a factor of 2, the gain of photoprotection was multiplied by a factor of 5. This indicates that the photoprotection provided by the nontronite is not a purely mechanical shielding effect but is also due to stabilizing interactions. No new evolution product was firmly identified, but the results obtained with urea suggest a particular reactivity in the presence of nontronite, leading to an increase of its dissociation rate.

  17. Sliding mode control for a class of nonlinear discrete-time networked systems with multiple stochastic communication delays

    NASA Astrophysics Data System (ADS)

    Ma, Lifeng; Wang, Zidong; Niu, Yugang; Bo, Yumimg; Guo, Zhi

    2011-04-01

    In this article, a sliding mode control problem is studied for a class of uncertain nonlinear networked systems with multiple communication delays. A sequence of stochastic variables obeying Bernoulli distribution is applied in the system model to describe the randomly occurring communication delays. The discrete-time system considered is also subject to parameter uncertainties and state-dependent stochastic disturbances. A novel discrete switching function is proposed to facilitate the sliding mode controller design. The sufficient conditions are derived by means of the linear matrix inequality (LMI) approach. It is shown that the system dynamics in the specified sliding surface is robustly exponentially stable in the mean square if two LMIs with an equality constraint are feasible. A discrete-time SMC controller is designed that is capable of guaranteeing the discrete-time sliding-mode reaching condition of the specified sliding surface. Finally, a simulation example is given to show the effectiveness of the proposed method.

  18. The Reloca Slide offshore Central Chile (35.5°S) - a Revision Based on Geotechnical Sliding Plane Characterization and Tsunami Modeling

    NASA Astrophysics Data System (ADS)

    Voelker, D.; Kopf, A.; Ikari, M.; Trütner, S.

    2015-12-01

    Reloca Slide is a submarine failure of ~ 24 km3 volume at the lower slope of the continental margin of Central Chile. The sliding event appears to be of post-Last Glacial Maximum (LGM) age. The evacuation site exhibits a 30° steep and 2000 m high failure plane, the slide deposits in the Chile Trench are preserved as scattered 10-600 m high angular blocks incorporated in a ~60 m high debris fan. The combination of a steep and high failure surface (high velocity) and the apparent cohesiveness of the displaced material (little disintegration) makes Reloca Slide a likely source for a local tsunami. Our numerical simulations show that a comparable event at the lower slope would generate waves of > 8 m offshore amplitude that would impact the Chilean coast within ~25 minutes. Reloca Slide is unique along the Central Chilean margin by its size and particular morphology. Yet, much of the unfailed lower slope along a ~1500 km long stretch shares general morphology, tectonic situation and sedimentary properties with the Reloca Slide source region. It is therefore of high relevance for risk mitigation to understand preconditioning factors and triggering mechanisms of as critical boundary conditions for similar potential future events. Core samples were taken directly from the failure plane, oedometer tests indicate a former burial depth of ~ 500 m. Samples are used to run geotechnical experiments for an improved understanding of the mechanics of the failure process. We are particularly interested in the question of whether the failure of the lowermost slope is a continuing process linked to the subduction of the Nazca Plate (e.g. a process needed to re-establish a critically tapered accretionary wedge), or, alternatively, if it is related to particular local conditions or an exceptional triggering event. We report on results from direct and rotary shear experiments to characterize frictional properties and strength of the materials at the detachment surface of the slide.

  19. The Louisiana Slide Library; A Humanities Program. Bulletin 1755.

    ERIC Educational Resources Information Center

    Louisiana Council for Music and Performing Arts, New Orleans.

    The Louisiana Slide Library is an extensive collection of slides, lectures, and tapes designed for use in the arts, the humanities, social and ethnic studies, languages, home economics, careers, crafts, and special education. This bibliography lists these slide sets and indicates the grade level intended for each set and the number of slides in…

  20. Sliding simulation of automotive brake primary contact with variable amounts of copper and graphite nanoparticles

    NASA Astrophysics Data System (ADS)

    Dmitriev, A. I.; Österle, W.

    2016-11-01

    Copper is one of the most important components in brake pads and its amount can reach up to 14%. In spite of a number of positive features copper usage in brake pad formulations has recently become the subject of considerable discussions, primarily due to concerns about potential risks related to environmental impacts of copper particles. So, for developing new pad formulations with possible replacements of copper content, it is very important to understand the functionality of copper additions to brake friction materials. In the paper theoretical investigation of the role of copper as a pad ingredient was carried out on the basis of modelling by the method of movable cellular automata (MCA). In the study the concentration of copper particles in a Fe3O4-matrix was varied. The sliding simulations were performed while assuming material properties at 500°C in order to assess the beneficial role of copper during severe braking conditions corresponding to fading cycles during dynamometer testing.

  1. Towards identifying the dynamics of sliding by acoustic emission and vibration

    NASA Astrophysics Data System (ADS)

    Korchuganov, M. A.; Filippov, A. V.; Tarasov, S. Yu.; Podgornyh, O. A.; Shamarin, N. N.; Filippova, E. O.

    2016-11-01

    The results of experiments with high load and sliding speed sliding conditions on tribologically mated pairs such as steel 1045/steel 1045 (test 1), steel 1045/basalt (test 2) and Hadfield steel/basalt (test 3) have been carried out in order to identify their response in terms of the acoustic emission and vibration signals. The steel to rock and rock to steel transfer has been revealed by examining the worn surfaces of both steel and rock samples with the use of laser scanning microscopy. The AE signal characteristics have been determined for the tribological pairs studied. The dynamics of sliding has been evaluated by measuring the vibration accelerations. Relationship between wear mode and either acoustic emission signal or vibration signal has been established. The minimal vibration oscillations amplitude and acoustic emission signal energy have been found out in sliding Hadfield steel/basalt pair.

  2. Micro and Nano-structure Development and Multiscale Physics at Sliding Metal Interfaces

    SciTech Connect

    Rigney; David; A.

    2006-06-01

    This final report describes research on the response of ductile materials to extreme loading conditions and high strain rates during impact combined with sliding friction. The work has involved a collaboration among two groups at Los Alamos National Laboratory and a tribology research grouup at The Ohio State University. The project involved experimental work and computer simulations at both laboratories and continuum mechanics analysis at OSU, supplemented by testing at AWE, Harwell, UK. Results demonstrated the importance of vorticity and mechanical mixing near the sliding interface in the development of nanocrystalline tribomaterial that is far from equilibrium. The work also revealed that strain rate sensitivity is an important materials property for determining the development of the velocity profile during sliding. As such, it is a property that is key to understanding the evolution of sliding behavior.

  3. Fast numerical calculations of EHD sliding traction forces Application to rolling bearings

    NASA Technical Reports Server (NTRS)

    Houpert, L.

    1984-01-01

    Based on analytical calculations assuming isothermal elastohydrodynamic (EHD) lubrication conditions, and on curve-fitting of a thermal correction factor, a new formula is proposed to calculate the sliding traction force developed in a concentrated contact, assuming a nonlinear, viscoelastic lubricant and undirectional sliding. When sliding occurs in the rolling and transverse directions (bidimensional sliding), a simplified numerical method is outlined by which the components of the local shear stress are quickly calculated. The latter method is applied to the calculation of the shear stress and temperature distribution in the ball-raceway contacts of an angular-contact ball bearing. Because of the viscoelastic behavior of the lubricant, a nonzero lateral traction force is obtained.

  4. Triboelectrical charge generated by frictional sliding contact between polymeric materials

    NASA Astrophysics Data System (ADS)

    Zeghloul, T.; Neagoe, M. B.; Prawatya, Y. E.; Dascalescu, L.

    2017-02-01

    The polymers used regularly in mechanical assemblies are brought up in relative sliding. The electrostatic charges generated in these functional conditions are merely known. Many factors are involved in the triboelectric charging process: normal load, the sliding velocity. The aim of this paper is to analyse the influence of these factors in the repartition and evolution of the electric potential at the surface in contact. The tribocharging experiments are carried out with samples cut from three polymers: sample A (5 mm x 15 mm x100 mm) from Acrylonitrile Butadiene Styrene (ABS) or Polypropylene (PP), and sample B (5 mm x 50 mm x 180 mm) from Polyvinyl Chloride (PVC). The normal load is set to four values in the range 2 to 14 N, and the sliding velocity is varied between 70 and 122 mm/s. The results point out that the variation of relative velocity between samples is not changing the average potential for the sample B. The surface potential has a linear increase with the normal load.

  5. A sliding cell technique for diffusion measurements in liquid metals

    SciTech Connect

    Geng, Yongliang; Zhu, Chunao; Zhang, Bo

    2014-03-15

    The long capillary and shear cell techniques are the usual methods for diffusion measurements in liquid metals. Here we present a new “sliding cell technique” to measure interdiffusion in liquid alloys, which combines the merits of these two methods. Instead of a number of shear cells, as used in the shear cell method, only one sliding cell is designed to separate and join the liquid diffusion samples. Using the sliding cell technique, the influence of the heating process (which affects liquid diffusion measurements in the conventional long capillary method) can be eliminated. Time-dependent diffusion measurements at the same isothermal temperature were carried out in Al-Cu liquids. Compared with the previous results measured by in-situ X-ray radiography, the obtained liquid diffusion coefficient in this work is believed to be influenced by convective flow. The present work further supports the idea that to obtain accurate diffusion constants in liquid metals, the measurement conditions must be well controlled, and there should be no temperature gradients or other disturbances.

  6. A sliding cell technique for diffusion measurements in liquid metals

    NASA Astrophysics Data System (ADS)

    Geng, Yongliang; Zhu, Chunao; Zhang, Bo

    2014-03-01

    The long capillary and shear cell techniques are the usual methods for diffusion measurements in liquid metals. Here we present a new "sliding cell technique" to measure interdiffusion in liquid alloys, which combines the merits of these two methods. Instead of a number of shear cells, as used in the shear cell method, only one sliding cell is designed to separate and join the liquid diffusion samples. Using the sliding cell technique, the influence of the heating process (which affects liquid diffusion measurements in the conventional long capillary method) can be eliminated. Time-dependent diffusion measurements at the same isothermal temperature were carried out in Al-Cu liquids. Compared with the previous results measured by in-situ X-ray radiography, the obtained liquid diffusion coefficient in this work is believed to be influenced by convective flow. The present work further supports the idea that to obtain accurate diffusion constants in liquid metals, the measurement conditions must be well controlled, and there should be no temperature gradients or other disturbances.

  7. A Family of Convective-Like Energy-Stable Outflow Boundary Conditions for Incompressible Flow Simulations on Severely-Truncated Unbounded Domains

    NASA Astrophysics Data System (ADS)

    Dong, Suchuan

    2016-11-01

    A large class of flow problems are spatially developing and involves physically unbounded domains, e.g. wakes, jets, and shear layers. To numerically simulate such problems, it is necessary to truncate the domain to a finite size, and some open boundary condition (a.k.a. outflow boundary condition) will be required at the artificial boundary. Backflow instability is a commonly encountered issue with outflows or open boundaries at moderate and high Reynolds numbers. Simulations have been observed to instantly blow up when strong vortices or backflows occur at the outflow/open boundary. In this talk we present a family of convective-like open boundary conditions that effectively overcomes the backflow instability. A prominent feature of these boundary conditions is that they all ensure the energy stability of the system, even in situations where strong vortices or backflows occur at the outflow/open boundary. The proposed boundary conditions unify and provide an underlying connection between the usual convective boundary condition and the traction-free boundary condition. Several canonical wake and jet problems in open domains will be presented to demonstrate the accuracy and effectiveness of the method for overcoming backflow instability. This work is partially supported by NSF (DMS-1318820 and DMS-1522537).

  8. Theory of sliding-mode triboelectric nanogenerators.

    PubMed

    Niu, Simiao; Liu, Ying; Wang, Sihong; Lin, Long; Zhou, Yu Sheng; Hu, Youfan; Wang, Zhong Lin

    2013-11-20

    The triboelectric nanogenerator (TENG) is a powerful approach toward new energy technology, especially for portable electronics. A theoretical model for the sliding-mode TENG is presented in this work. The finite element method was utilized to characterize the distributions of electric potential, electric field, and charges on the metal electrodes of the TENG. Based on the FEM calculation, the semi-analytical results from the interpolation method and the analytical V-Q-x relationship are built to study the sliding-mode TENG. The analytical V-Q-x equation is validated through comparison with the semi-analytical results. Furthermore, based on the analytical V-Q-x equation, dynamic output performance of sliding-mode TENG is calculated with arbitrary load resistance, and good agreement with experimental data is achieved. The theory presented here is a milestone work for in-depth understanding of the working mechanism of the sliding-mode TENG, and provides a theoretical basis for further enhancement of the sliding-mode TENG for both energy scavenging and self-powered sensor applications.

  9. Resistance to Sliding on Atomic Scales

    NASA Technical Reports Server (NTRS)

    Dominik, C.; Tielens, A.; Cuzzi, Jeffrey (Technical Monitor)

    1995-01-01

    The structure and stability of agglomerates of micron-sized particles is determined by the mechanical properties of the individual contacts between the constituent particles. In this paper we study the possibility of aggregate rearrangements by sliding. Since the contacts between (sub)micron particles are only a few hundred atoms in diameter, processes on atomic levels will play the dominating roll. We study a theoretical model of sliding friction for surfaces that are either flat or contain steps in their grids. The results show that sliding over flat surfaces may produce a large range of friction coefficients, including zero if the adhesive forces are small compared to the binding forces inside a body. However, both grid alignment and steps in the surface will lead to high values for friction. These processes combined virtually eliminate the possibility of sliding in a collision of two (sub)micron sized particles at velocities low enough for sticking to occur. On the other hand we show that in collisions between aggregates sliding may be an important factor for energy dissipation and compaction.

  10. Slide-Ring Materials Using Cyclodextrin.

    PubMed

    Ito, Kohzo

    2017-01-01

    We have recently synthesized slide-ring materials using cyclodextrin by cross-linking polyrotaxanes, a typical supramolecule. The slide-ring materials have polymer chains with bulky end groups topologically interlocked by figure-of-eight shaped junctions. This indicates that the cross-links can pass through the polymer chains similar to pulleys to relax the tension of the backbone polymer chains. The slide-ring materials also differ from conventional polymers in that the entropy of rings affects the elasticity. As a result, the slide-ring materials show quite small Young's modulus not proportional to the cross-linking density. This concept can be applied to a wide variety of polymeric materials as well as gels. In particular, the slide-ring materials show remarkable scratch-proof properties for coating materials for automobiles, cell phones, mobile computers, and so on. Further current applications include vibration-proof insulation materials for sound speakers, highly abrasive polishing media, dielectric actuators, and so on.

  11. Assessing visual attention in young children and adolescents with severe mental retardation utilizing conditional-discrimination tasks and multiple testing procedures.

    PubMed

    Huguenin, Nancy H

    2004-01-01

    To effectively reduce overselective attention, a fine-grained analysis of the control exhibited by compound training cues is first needed. Computer software was developed in this study to administer two different stimulus control-testing procedures to assess how three young children of normal development and three adolescents with severe mental retardation attended to stimulus compounds when conditional-discrimination tasks were provided. One test assessed stimulus control by determining response accuracy for each component of the S+ compounds. The other testing procedure measured the response topographies of the compound stimuli using a touch screen attached to a computer monitor screen. After pretraining each stimulus component, all three children attended simultaneously to two elements in a conditional-discrimination task with few errors occurring. The adolescents with mental retardation eventually attended to both elements simultaneously but required more pretraining and exposure to the conditional-discrimination tasks before simultaneous attention occurred. Since the adolescents with severe mental retardation learned to simultaneously attend to multiple cues in the conditional-discrimination tasks, this demonstrated that restricted attention is not an unmodifiable perceptual characteristic among individuals with developmental disabilities. Recording response topographies with a touch screen was also discovered to be a sensitive measure of stimulus preferences for both groups. Utilizing touch-screen technology may prove to be critical for accurately identifying stimulus preferences and contribute to the understanding and treatment of overselective attention in students with attentional deficits.

  12. NEMD simulations for ductile metal sliding

    SciTech Connect

    Hammerberg, James E; Germann, Timothy C; Ravelo, Ramon J; Holian, Brad L

    2011-01-31

    We have studied the sliding behavior for a 19 M Al(110)/Al(110) defective crystal at 15 GPa as a function of relative sliding velocity. The general features are qualitatively similar to smaller scale (1.4 M) atom simulations for Al(111)/Al(110) nondefective single crystal sliding. The critical velocity, v{sub c}, is approximately the same for the defective crystal as the size scaled v{sub c}. The lower velocity tangential force is depressed relative to the perfect crystal. The critical temperature, T*, is depressed relative to the perfect crystal. These conclusions are consistent with a lower value for f{sub c} for the defective crystal. The detailed features of structural transformation and the high velocity regime remain to be mapped.

  13. Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults.

    PubMed

    Phawong, Chintana; Ouma, Collins; Tangteerawatana, Piyatida; Thongshoob, Jarinee; Were, Tom; Mahakunkijcharoen, Yuvadee; Wattanasirichaigoon, Duangrurdee; Perkins, Douglas Jay; Khusmith, Srisin

    2010-06-01

    Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40 subunit is associated with susceptibility to severe malaria in African populations. Since the role of genetic variation in conditioning severe malaria in Thai adults is largely unexplored, the functional association between IL12B polymorphisms [i.e. IL12Bpro (rs17860508) and IL12B 3' UTR T/G (rs3212227)], severe malaria and cytokine production was examined in patients with Plasmodium falciparum infections (n = 355) recruited from malaria endemic areas along the Thai-Myanmar border in northwest Thailand. Circulating IL-12p40 (p = 0.049) and IFN-gamma (p = 0.051) were elevated in patients with severe malaria, while only IL-12p40 was significantly higher in severe malaria patients with hyperparasitaemia (p = 0.046). Carriage of the IL12Bpro1.1 genotype was associated with enhanced severity of malaria (OR, 2.34; 95% CI, 0.94-5.81; p = 0.066) and hyperparasitaemia (OR, 3.42; 95% CI, 1.17-9.87; p = 0.025) relative to the IL12Bpro2.2 genotype (wild type). Individuals with the IL12Bpro1.1 genotype also had the lowest IL-12p40 (p = 0.002) and the highest IFN-gamma (p = 0.004) levels. Construction of haplotypes revealed that carriage of the IL12Bpro-2/3' UTR-T haplotype was associated with protection against severe malaria (OR, 0.51; 95% CI, 0.29-0.90; p = 0.020) and reduced circulating IFN-gamma (p = 0.06). Thus, genotypic and haplotypic variation at IL12Bpro and IL12B 3' UTR in this population influences susceptibility to severe malaria and functional changes in circulating IL-12p40 and IFN-gamma levels. Results presented here suggest that protection against severe malaria in Thai adults is associated with genotypic variants that condition enhanced IL-12p40 and reduced IFN-gamma levels.

  14. Coated Glass Slides TACAS Are Applicable to Heat-Assisted Immunostaining and In Situ Hybridization at the Electron Microscopy Level

    PubMed Central

    Matsui, Takahiro; Onouchi, Takanori; Shiogama, Kazuya; Mizutani, Yasuyoshi; Inada, Ken-ichi; Yu, Fuxun; Hayasaka, Daisuke; Morita, Koichi; Ogawa, Hirohisa; Mahara, Fumihiko; Tsutsumi, Yutaka

    2015-01-01

    We performed pre-embedding electron microscopic study for visualizing the antigen and genome of severe fever with thrombocytopenia syndrome (SFTS) virus in the cytoplasm of macrophages of the human splenic red pulp, both requesting preheating treatment of sections. To pursue this, coated glass slides with unique characteristics are needed. Namely, during staining they must prevent detaching off sections, but after staining the sections must be transferred to epoxy resin. Aminopropyltriexoxysilane-coated glass slides, widely used for immunostaining, were resistant to transfer to epoxy resin. In contrast, coated glass slides designated as Thinlayer Advanced Cytology Assay System (TACAS) were suitable for this purpose. The technique is also applicable to the coated glass slide-requiring cytology practice, in which immunocytochemical evaluation is needed after cell transfer to another glass slide. PMID:26633907

  15. New views of the Cape Fear slide in the U. S. East coast gas hydrate province

    NASA Astrophysics Data System (ADS)

    Wood, W.; Lindwall, D.; Gettrust, J.

    2003-04-01

    The Cape Fear slide is one of the largest slope failure features on the U.S. coast, beginning about 200 km southeast of Cape Fear, North Carolina. The failure area is about 37 km long and 10 to 12 km wide, resulting in a debris flow up to 70 km wide and 300 km long, and occurs in a large methane hydrate province, although evidence of a BSR below the slide is weak. All but the head wall of the slide lies below 2000 meters water depth, making detailed seismic imaging difficult. Recently, however, (summer 2002) several seismic transects across portions of the slide (including the diapir in the slide scar) were acquired with a deep-towed multichannel seismic system (DTAGS). The 48 channel, 420 m offset system operates at 220-1000 Hz, at a few hundred meters above the seafloor. The data reveal sedimentary layering within the slide which is laterally discontinuous, suggesting at least some post depositional faulting and possible conduits for fluid and methane migration.

  16. Musical slide show MAF with protection and governance using MPEG-21 IPMP Components and REL

    NASA Astrophysics Data System (ADS)

    Sabirin, Muhammad Syah Houari; Tan, Hendry; Lim, Jeongyeon; Kim, Munchurl

    2007-02-01

    The Musical Slide Show Multimedia Application Format (MAF) which is currently being standardized by the Moving Picture Expert Group (MPEG) conveys the concept of combining several established standard technologies in a single file format. It defines the format of packing up MP3 audio data, along with JPEG images, MPEG-7 Simple Profile metadata, timed text, and MPEG-4 LASeR script. The presentation of Musical Slide Show MAF contents is made in a synchronized manner with JPEG images, timed text to MP3 audio track. Also, the rendering effect on JPEG images can be supported by the MPEG-4 LASeR script. This Musical Slide Show MAF will enrich the consumption of MP3 contents assisted with synchronized and rendered JPEG images, text as well as MPEG-7 metadata about the MP3 audio contents. However, there is no protection and governance mechanism for Musical Slide Show MAF which is the essential elements to deploy the sorts of contents. In this paper, to manage the Musical Slide Show MAF contents in a controlled manner, we present a protection and governance mechanism by using MPEG-21 Intellectual Property Management and Protection (IPMP) Components and MPEG-21 Rights Expression Language (REL) technologies We implement an authoring tool and a player tool for Musical Slide Show MAF contents and show the experimental results as well.

  17. Develop and Manufacture an airlock sliding tray

    SciTech Connect

    Lawton, Cindy M.

    2014-02-26

    Objective: The goal of this project is to continue to develop an airlock sliding tray and then partner with an industrial manufacturing company for production. The sliding tray will be easily installed into and removed from most glovebox airlocks in a few minutes. Technical Approach: A prototype of a sliding tray has been developed and tested in the LANL cold lab and 35 trays are presently being built for the plutonium facility (PF-4). The current, recently approved design works for a 14-inch diameter round airlock and has a tray length of approximately 20 inches. The grant will take the already tested and approved round technology and design for the square airlock. These two designs will be suitable for the majority of the existing airlocks in the multitude of DOE facilities. Partnering with an external manufacturer will allow for production of the airlock trays at a much lower cost and increase the availability of the product for all DOE sites. Project duration is estimated to be 12-13 months. Benefits: The purpose of the airlock sliding trays is fourfold: 1) Mitigate risk of rotator cuff injuries, 2) Improve ALARA, 3) Reduce risk of glovebox glove breaches and glove punctures, and 4) Improve worker comfort. I have had the opportunity to visit many other DOE facilities including Savannah, Y-12, ORNL, Sandia, and Livermore for assistance with ergonomic problems and/or injuries. All of these sites would benefit from the airlock sliding tray and I can assume all other DOE facilities with gloveboxes built prior to 1985 could also use the sliding trays.

  18. Sliding Wear Response of Beryl Reinforced Aluminum Composite - A Factorial Design Approach

    NASA Astrophysics Data System (ADS)

    Bharat, V.; Durga Prasad, B.; Prabhakar, M. Bhovi; Venkateswarlu, K.

    2016-02-01

    Al-Beryl MMCs were successfully fabricated using powder metallurgy route. Processing conditions such as beryl content and particle size were varied and its influence on dry sliding wear response was studied. Effect of test parameters like applied load and sliding distance on wear performance of Al-Beryl MMCs were discussed detail. Sliding wear tests were conducted using a pin on disc machine based on the 24 (4 factors at 2 levels) factorial design. Analysis of variance (ANOVA) was performed to obtain the contribution of control parameters on wear rate. The present study shows that wear resistance of Al-beryl MMCs not only depends on the beryl content but also influenced by normal load, sliding distance and particle size. The results show that most significant variables affecting wear rate of Al - beryl MMCs are size of the beryl particles (22%), beryl content (19.60%), sliding distance (18.47%), and normal load (10.30%). The interaction effects of these parameters are less significant in influencing wear rate compared to the individual parameters. The correlation between sliding wear and its parameters was obtained by multiple regression analysis. Regression model developed in the present study can be successfully implemented to predict the wear response of Al-Beryl MMCs.

  19. An Adaptive Supervisory Sliding Fuzzy Cerebellar Model Articulation Controller for Sensorless Vector-Controlled Induction Motor Drive Systems

    PubMed Central

    Wang, Shun-Yuan; Tseng, Chwan-Lu; Lin, Shou-Chuang; Chiu, Chun-Jung; Chou, Jen-Hsiang

    2015-01-01

    This paper presents the implementation of an adaptive supervisory sliding fuzzy cerebellar model articulation controller (FCMAC) in the speed sensorless vector control of an induction motor (IM) drive system. The proposed adaptive supervisory sliding FCMAC comprised a supervisory controller, integral sliding surface, and an adaptive FCMAC. The integral sliding surface was employed to eliminate steady-state errors and enhance the responsiveness of the system. The adaptive FCMAC incorporated an FCMAC with a compensating controller to perform a desired control action. The proposed controller was derived using the Lyapunov approach, which guarantees learning-error convergence. The implementation of three intelligent control schemes—the adaptive supervisory sliding FCMAC, adaptive sliding FCMAC, and adaptive sliding CMAC—were experimentally investigated under various conditions in a realistic sensorless vector-controlled IM drive system. The root mean square error (RMSE) was used as a performance index to evaluate the experimental results of each control scheme. The analysis results indicated that the proposed adaptive supervisory sliding FCMAC substantially improved the system performance compared with the other control schemes. PMID:25815450

  20. Radiation-Sensitive Severe Combined Immunodeficiency: The arguments for and against conditioning prior to hematopoietic cell transplantation – What to do?

    PubMed Central

    Cowan, MJ; Gennery, AR

    2015-01-01

    Defects in DCLRE1C, PRKDC, LIG4, NHEJ1, and NBS1, involving the non-homologous end joining (NHEJ) DNA repair pathway, result in radiation-sensitive severe combined immunodeficiency (RS-SCID). Results of hematopoietic cell transplantation for RS-SCID suggest that minimizing exposure to alkylating agents and ionizing radiation is important for optimizing survival and minimizing late effects. However, use of pre-conditioning with alkylating agents is associated with a greater likelihood of full T and B cell reconstitution compared to no conditioning or immunosuppression alone. A reduced intensity regimen using fludarabine and low dose cyclophosphamide may be effective for patients with LIG4, NHEJ1 and NBS1 defects although more data are needed to confirm these findings and characterize late effects. For patients with mutations in DCLRE1C (Artemis-deficient SCID), there is no optimal approach that uses standard dose alkylating agents without significant late effects. Until non-chemotherapy agents, e.g., anti-CD45 or anti-CD117 become available, options include minimizing exposure to alkylators, e.g., single agent low dose targeted Busulfan or achieving T cell reconstitution followed several years later with a conditioning regimen to restore B cell immunity. Gene therapy for these disorders will eventually remove the issues of rejection and GvHD. Prospective multi- center studies are needed to evaluate these approaches in this rare but highly vulnerable patient population. PMID:26055221

  1. Strapping rowers to their sliding seat improves performance during the start of single-scull rowing.

    PubMed

    van Soest, A J Knoek; de Koning, H; Hofmijster, M J

    2016-09-01

    In this study, the effect of strapping rowers to their sliding seat on performance during 75 m on-water starting trials was investigated. Well-trained rowers performed 75 m maximum-effort starts using an instrumented single scull equipped with a redesigned sliding seat system, both under normal conditions and while strapped to the sliding seat. Strapping rowers to their sliding seat resulted in a 0.45 s lead after 75 m, corresponding to an increase in average boat velocity of about 2.5%. Corresponding effect sizes were large. No significant changes were observed in general stroke cycle characteristics. No indications of additional boat heaving and pitching under strapped conditions were found. The increase in boat velocity is estimated to correspond to an increase in average mechanical power output during the start of on-water rowing between 5% and 10%, which is substantial but smaller than the 12% increase found in a previous study on ergometer starting. We conclude that, after a very short period of adaptation to the strapped condition, single-scull starting performance is substantially improved when the rower is strapped to the sliding seat.

  2. Geo-structural modelling for potential large rock slide in Machu Picchu

    NASA Astrophysics Data System (ADS)

    Spizzichino, D.; Delmonaco, G.; Margottini, C.; Mazzoli, S.

    2009-04-01

    The monumental complex of the Historical Sanctuary of Machu Picchu, declared as World Heritage Site by UNESCO in 1983, is located in the Andean chain at approx. 80 km from Cuzco (Peru) and at an elevation of 2430 m a.s.l. along the Urubamba River Valley. From a geological point of view, the Machu Picchu granitoid pluton, forming part of the larger "Quillabamba granite", is one of a series of plutons intruded along the axial zone of the high Eastern Cordillera Permo-Liassic rift system including a variety of rock types, dominantly granites and granodiorites. The most evident structures at the outcrop scale consist of planar joint sets that may be variably reactivated and exhibiting 4 main orientations. At present, the site is affected by geological risk due to frequent landslides that threaten security and tourist exploitation. In the last years, the international landslide scientific community has promoted a multi-discipline joint programme mainly finalised to slope deformation monitoring and analysis after the warning, launched in 2001, of a potential collapse of the citadel, caused by a huge rock slide. The contribute of the Italian research team was devoted to implement a landslide risk analysis and an innovative remote sensing techniques. The main scope of this work is to present the implementation of a geo-structural modelling aimed at defining present and potential slope stability conditions of the Machu Picchu Citadel. Data have been collected by geological, structural and geomechanical field surveys and laboratory tests in order to reconstruct the geomorphological evolution of the area. Landslide types and evolution are strictly controlled by regional tectonic uplift and structural setting. Several slope instability phenomena have been identified and classified according to mechanism, material involved and state of activity. Rock falls, debris flows, rock slides and debris slides are the main surveyed landslide types. Rock slides and rock falls may produce

  3. Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?

    PubMed

    Hindriks, R; Adhikari, M H; Murayama, Y; Ganzetti, M; Mantini, D; Logothetis, N K; Deco, G

    2016-02-15

    During the last several years, the focus of research on resting-state functional magnetic resonance imaging (fMRI) has shifted from the analysis of functional connectivity averaged over the duration of scanning sessions to the analysis of changes of functional connectivity within sessions. Although several studies have reported the presence of dynamic functional connectivity (dFC), statistical assessment of the results is not always carried out in a sound way and, in some studies, is even omitted. In this study, we explain why appropriate statistical tests are needed to detect dFC, we describe how they can be carried out and how to assess the performance of dFC measures, and we illustrate the methodology using spontaneous blood-oxygen level-dependent (BOLD) fMRI recordings of macaque monkeys under general anesthesia and in human subjects under resting-state conditions. We mainly focus on sliding-window correlations since these are most widely used in assessing dFC, but also consider a recently proposed non-linear measure. The simulations and methodology, however, are general and can be applied to any measure. The results are twofold. First, through simulations, we show that in typical resting-state sessions of 10 min, it is almost impossible to detect dFC using sliding-window correlations. This prediction is validated by both the macaque and the human data: in none of the individual recording sessions was evidence for dFC found. Second, detection power can be considerably increased by session- or subject-averaging of the measures. In doing so, we found that most of the functional connections are in fact dynamic. With this study, we hope to raise awareness of the statistical pitfalls in the assessment of dFC and how they can be avoided by using appropriate statistical methods.

  4. Sliding mode control of wind-induced vibrations using fuzzy sliding surface and gain adaptation

    NASA Astrophysics Data System (ADS)

    Thenozhi, Suresh; Yu, Wen

    2016-04-01

    Although fuzzy/adaptive sliding mode control can reduce the chattering problem in structural vibration control applications, they require the equivalent control and the upper bounds of the system uncertainties. In this paper, we used fuzzy logic to approximate the standard sliding surface and designed a dead-zone adaptive law for tuning the switching gain of the sliding mode control. The stability of the proposed controller is established using Lyapunov stability theory. A six-storey building prototype equipped with an active mass damper has been used to demonstrate the effectiveness of the proposed controller towards the wind-induced vibrations.

  5. Impact Driver With Integral Sliding Hammer

    NASA Technical Reports Server (NTRS)

    Wallace, Bilby J.

    1987-01-01

    Tool combines impact driver with sliding dead-blow hammer. Used for any purpose for which ordinary impact driver used; tightening fasteners or driving starter holes for drill. Tool protects user from accidental injury and surrounding equipment from damage that might occur from ordinary arm-wielded hammer. Especially useful in underwater work.

  6. Enhancing Creative Thinking through Designing Electronic Slides

    ERIC Educational Resources Information Center

    Mokaram, Al-Ali Khaled; Al-Shabatat, Ahmad Mohammad; Fong, Fook Soon; Abdallah, Andaleeb Ahmad

    2011-01-01

    During the shifting of teaching and learning methods using computer technologies, much emphasis was paid on the knowledge content more than the thinking skills. Thus, this study investigated the effects of a computer application, namely, designing electronic slides on the development of creative thinking skills of a sample of undergraduate…

  7. Particle Sliding on a Rough Incline

    ERIC Educational Resources Information Center

    Zurcher, Ulrich

    2007-01-01

    We study a particle sliding on a rough inclined plane as an example of a mechanical problem with nonholonomic constraint. The particle is launched in an arbitrary direction so that its motion has both a horizontal and a "vertical" (i.e., up- and downhill) direction. The friction force acts along the instantaneous velocity, so that the horizontal…

  8. Cooling Characteristics of the V-1650-7 Engine. II - Effect of Coolant Conditions on Cylinder Temperatures and Heat Rejection at Several Engine Powers

    NASA Technical Reports Server (NTRS)

    Povolny, John H.; Bogdan, Louis J.; Chelko, Louis J.

    1947-01-01

    An investigation has been conducted on a V-1650-7 engine to determine the cylinder temperatures and the coolant and oil heat rejections over a range of coolant flows (50 to 200 gal/min) and oil inlet temperatures (160 to 2150 F) for two values of coolant outlet temperature (250 deg and 275 F) at each of four power conditions ranging from approximately 1100 to 2000 brake horsepower. Data were obtained for several values of block-outlet pressure at each of the two coolant outlet temperatures. A mixture of 30 percent by volume of ethylene glycol and 70-percent water was used as the coolant. The effect of varying coolant flow, coolant outlet temperature, and coolant outlet pressure over the ranges investigated on cylinder-head temperatures was small (0 deg to 25 F) whereas the effect of increasing the engine power condition from ll00 to 2000 brake horsepower was large (maximum head-temperature increase, 110 F).

  9. MECHANICAL AND CHEMICAL PROPERTIES OF CEMENTITIOUS MATERIALS USING γ-2CaO.SiO2 UNDER THE SEVERAL CONDITIONS IN ACCELERATED CARBONATION CURING

    NASA Astrophysics Data System (ADS)

    Watanabe, Kenzo; Yokozeki, Kosuke; Torichigai, Takeshi; Sakai, Etsuo

    The experiments have been conducted in order to investigate the mechanical and chemical properties of mortar with three different binders under the several conditions in accelerated carbonation curing. As the results, the depth of carbonation varied among each mix proportion. It is proven that by increasing CO2 density in the mortar having γ-2CaO.SiO2, the CaCO3 production will increase, which leads to the increase of filling ability in the pore of mortar. Furthermore, as a result from the calculation of Tritium permeation, it shows that the permeation decreases with an increase of CO2 density.

  10. The risk of polyomavirus BK-associated hemorrhagic cystitis after allogeneic hematopoietic SCT is associated with myeloablative conditioning, CMV viremia and severe acute GVHD.

    PubMed

    Uhm, J; Hamad, N; Michelis, F V; Shanavas, M; Kuruvilla, J; Gupta, V; Lipton, J H; Messner, H A; Seftel, M; Kim, D D

    2014-12-01

    Hemorrhagic cystitis (HC) is a common complication after allogeneic hematopoietic SCT (allo-HSCT). Several risk factors have been suggested including BU-containing myeloablative conditioning, unrelated donors and GVHD, but these have not been consistently reported. We conducted a retrospective study including 339 allo-HSCT recipients between 2009 and 2012. Of 339 patients, 79 (23.3%) developed HC with 2-year cumulative incidence of 24.0% (95% confidence interval, 19.4-28.9). The median onset time was 45 days (range, 16-430) after allo-HSCT. Sixty-two patients (84%) out of 74 evaluated for urine BK virus PCR testing showed a positive result (mean 2.0 × 10(10) copies of DNA per mL). In univariate analysis, myeloablative conditioning, HLA-mismatched donor, CMV viremia and acute GVHD (aGVHD) grade 3-4 were significantly associated with the risk of HC. Multivariate analysis confirmed all associating factors identified in univariate analysis except for HLA-mismatched donor: myeloablative conditioning (hazard ratio (HR) 2.63, P=0.003), CMV viremia (HR 1.88, P=0.014) and aGVHD grade 3-4 (HR 1.71, P=0.029). HC did not affect OS or non-relapse mortality. Symptomatic HC is a frequent complication following allo-HSCT, with a 2-year cumulative incidence of 24.0%. Three clinical factors associated with HC were identified including myeloablative conditioning, CMV viremia and severe aGVHD.

  11. Seismically reactivated Hattian slide in Kashmir, Northern Pakistan

    NASA Astrophysics Data System (ADS)

    Schneider, Jean F.

    2009-07-01

    The Pakistan 2005 earthquake, of magnitude 7.6, caused severe damage on landscape and infrastructure, in addition to numerous casualties. The event reactivated Hattian Slide, creating a rock avalanche in a location where earlier mass movements had happened already, as indicated by satellite imagery and ground investigation. The slide originated on Dana Hill, in the upper catchment area of Hattian on Karli Stream, a tributary of Jhelum River, Pakistan, and buried the hamlet Dandbeh and several farms nearby. A natural dam accumulated, impounding two lakes, the larger one threatening parts of downstream Hattian Village with flooding. An access road and artificial spillways needed to be constructed in very short time to minimize the flooding risk. As shown by this example, when pointing out the risk of large-scale damage to population and infrastructure by way of hazard indication maps of seismically active regions, and preparing for alleviation of that risk, it is advisable to consider the complete Holocene history of the slopes involved.

  12. Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood.

    PubMed

    Oomen, Charlotte A; Soeters, Heleen; Audureau, Nathalie; Vermunt, Lisa; van Hasselt, Felisa N; Manders, Erik M M; Joëls, Marian; Lucassen, Paul J; Krugers, Harm

    2010-05-12

    Early life stress increases the risk for developing stress-related pathologies later in life. Recent studies in rats suggest that mild early life stress, rather than being overall unfavorable, may program the hippocampus such that it is optimally adapted to a stressful context later in life. Here, we tested whether this principle of "adaptive programming" also holds under severely adverse early life conditions, i.e., 24 h of maternal deprivation (MD), a model for maternal neglect. In young adult male rats subjected to MD on postnatal day 3, we observed reduced levels of adult hippocampal neurogenesis as measured by cell proliferation, cell survival, and neuronal differentiation. Also, mature dentate granule cells showed a change in their dendritic morphology that was most noticeable in the proximal part of the dendritic tree. Lasting structural changes due to MD were paralleled by impaired water maze acquisition but did not affect long-term potentiation in the dentate gyrus. Importantly, in the presence of high levels of the stress hormone corticosterone, even long-term potentiation in the dentate gyrus of MD animals was facilitated. In addition to this, contextual learning in a high-stress environment was enhanced in MD rats. These morphological, electrophysiological, and behavioral observations show that even a severely adverse early life environment does not evolve into overall impaired hippocampal functionality later in life. Rather, adversity early in life can prepare the organism to perform optimally under conditions associated with high corticosteroid levels in adulthood.

  13. Comprehensive and Integrated Palliative Care for People With Advanced Chronic Conditions: An Update From Several European Initiatives and Recommendations for Policy.

    PubMed

    Gómez-Batiste, Xavier; Murray, Scott A; Thomas, Keri; Blay, Carles; Boyd, Kirsty; Moine, Sebastien; Gignon, Maxime; Van den Eynden, Bart; Leysen, Bert; Wens, Johan; Engels, Yvonne; Dees, Marianne; Costantini, Massimo

    2017-03-01

    The number of people in their last years of life with advanced chronic conditions, palliative care needs, and limited life prognosis due to different causes including multi-morbidity, organ failure, frailty, dementia, and cancer is rising. Such people represent more than 1% of the population. They are present in all care settings, cause around 75% of mortality, and may account for up to one-third of total national health system spend. The response to their needs is usually late and largely based around institutional palliative care focused on cancer. There is a great need to identify these patients and integrate an early palliative approach according to their individual needs in all settings, as suggested by the World Health Organization. Several tools have recently been developed in different European regions to identify patients with chronic conditions who might benefit from palliative care. Similarly, several models of integrated palliative care have been developed, some with a public health approach to promote access to all in need. We describe the characteristics of these initiatives and suggest how to develop a comprehensive and integrated palliative approach in primary and hospital care and to design public health and community-oriented practices to assess and respond to the needs in the whole population. Additionally, we report ethical challenges and prognostic issues raised and emphasize the need for research to test the various tools and models to generate evidence about the benefits of these approaches to patients, their families, and to the health system.

  14. Formation of metalsbnd F bonds during frictional sliding: Influence of water and applied load

    NASA Astrophysics Data System (ADS)

    Shen, J. T.; Pei, Y. T.; De Hosson, J. Th. M.

    2016-04-01

    Effects of water lubrication and applied load on the formation of PTFE transfer films and metalsbnd F bonds during sliding when PTFE filled composites sliding against steel and Al2O3 are investigated. In water-lubricated conditions, XPS analysis reveals that a thin layer of water molecules at the sliding interface inhibits the formation of PTFE transfer films and Alsbnd F bonds on the Al2O3 ball, leading to a detrimental effect on the tribo-performance. Under various normal loads in dry sliding condition, it is found that the smearing of PTFE onto the wear surface of the composite and the transfer of PTFE onto the surface of the steel counterpart are stimulated by a high load. During sliding, the contact pressure is found to be the driving force of the reaction between steel and PTFE. It is concluded that under various loads, the total amount of PTFE transfer films has a larger impact on the friction behavior than the formation of Fesbnd F bonds.

  15. How to Prepare Clay-Lift and Sandwich Slides.

    ERIC Educational Resources Information Center

    Barman, Charles R.

    1984-01-01

    Describes two techniques for making 35 millimeter slides without using photographic film. One method uses clear adhesive contact paper and the other uses transparency film. Both techniques are inexpensive and require only a few minutes of preparation per slide. (JM)

  16. Solenoid valve design minimizes vibration and sliding wear problem

    NASA Technical Reports Server (NTRS)

    Gillon, W. A., Jr.

    1968-01-01

    Two-way cryogenic solenoid valve resists damage from vibration and metallic interfacial sliding. The new system features a flat-faced armature guided by a flexure disk which eliminates sliding surfaces and is less subject to contamination and wear.

  17. Ovine HSP90AA1 Expression Rate Is Affected by Several SNPs at the Promoter under Both Basal and Heat Stress Conditions

    PubMed Central

    Salces-Ortiz, Judit; González, Carmen; Moreno-Sánchez, Natalia; Calvo, Jorge H.; Pérez-Guzmán, M. Dolores; Serrano, Magdalena M.

    2013-01-01

    The aim of this work was to investigate the association between polymorphisms located at the HSP90AA1 ovine gene promoter and gene expression rate under different environmental conditions, using a mixed model approach. Blood samples from 120 unrelated rams of the Manchega sheep breed were collected at three time points differing in environmental conditions. Rams were selected on the basis of their genotype for the transversion G/C located 660 base pairs upstream the gene transcription initiation site. Animals were also genotyped for another set of 6 SNPs located at the gene promoter. Two SNPs, G/C−660 and A/G−444, were associated with gene overexpression resulting from heat stress. The composed genotype CC−660-AG−444 was the genotype having the highest expression rates with fold changes ranging from 2.2 to 3.0. The genotype AG−522 showed the highest expression levels under control conditions with a fold change of 1.4. Under these conditions, the composed genotype CC−601-TT−524-AG−522-TT−468 is expected to be correlated with higher basal expression of the gene according to genotype frequencies and linkage disequilibrium values. Some putative transcription factors were predicted for binding sites where the SNPs considered are located. Since the expression rate of the gene under alternative environmental conditions seems to depend on the composed genotype of several SNPs located at its promoter, a cooperative regulation of the transcription of the HSP90AA1 gene could be hypothesized. Nevertheless epigenetic regulation mechanisms cannot be discarded. PMID:23826107

  18. "Discoveries in Planetary Sciences": Slide Sets Highlighting New Advances for Astronomy Educators

    NASA Astrophysics Data System (ADS)

    Brain, D. A.; Schneider, N. M.; Beyer, R. A.

    2010-12-01

    Planetary science is a field that evolves rapidly, motivated by spacecraft mission results. Exciting new mission results are generally communicated rather quickly to the public in the form of press releases and news stories, but it can take several years for new advances to work their way into college textbooks. Yet it is important for students to have exposure to these new advances for a number of reasons. In some cases, new work renders older textbook knowledge incorrect or incomplete. In some cases, new discoveries make it possible to emphasize older textbook knowledge in a new way. In all cases, new advances provide exciting and accessible examples of the scientific process in action. To bridge the gap between textbooks and new advances in planetary sciences we have developed content on new discoveries for use by undergraduate instructors. Called 'Discoveries in Planetary Sciences', each new discovery is summarized in a 3-slide PowerPoint presentation. The first slide describes the discovery, the second slide discusses the underlying planetary science concepts, and the third presents the big picture implications of the discovery. A fourth slide includes links to associated press releases, images, and primary sources. This effort is generously sponsored by the Division for Planetary Sciences of the American Astronomical Society, and the slide sets are available at http://dps.aas.org/education/dpsdisc/. Sixteen slide sets have been released so far covering topics spanning all sub-disciplines of planetary science. Results from the following spacecraft missions have been highlighted: MESSENGER, the Spirit and Opportunity rovers, Cassini, LCROSS, EPOXI, Chandrayan, Mars Reconnaissance Orbiter, Mars Express, and Venus Express. Additionally, new results from Earth-orbiting and ground-based observing platforms and programs such as Hubble, Keck, IRTF, the Catalina Sky Survey, HARPS, MEarth, Spitzer, and amateur astronomers have been highlighted. 4-5 new slide sets are

  19. Mechanism of sand slide - cold lahar induced by extreme rainfall

    NASA Astrophysics Data System (ADS)

    Fukuoka, Hiroshi; Yamada, Masumi; Dok, Atitkagna

    2014-05-01

    reveal the mechanism of rapid motion. In the undrained or partially drained tests under pore water pressure test, monotonic loading of shear stress, and constant shear speed conditions, we found that immediately after failure takes place, a big excess pore pressure was generated and accelerating motions had stated in all cases. The reduced shear resistance thereafter was maintained because of the lasting high pore pressure. Even in the partially-drained test, we found once the pore pressure reached almost same with the normal stress and then gradually decreased due to dissipation. Those tests apparently shows that the high mobility and high acceleration of the motion are expected and this could be the key mechanism of the fluidization of initial shallow slides into sand flows, i.e., cold lahars. In the past ring shear test series on volcanic materials from fluidized landslides at El Picaccho of El Salvador, Mt Aso of Kumamto Prefecture, and Nagari Tandikat near Padang, Indonesia, show very similar trends. In all those cases, we expected serious grain crushing during shear, contributed to the generation of excess pore pressure, because those material are deposited recently (in geological time) and suffered no big overburden pressure which means no consolidation and no serious grain crushing ever before. So those volcanic materials are generally susceptible to crushing and expect high mobility when slides are initiated under fully saturated condition.

  20. 7 CFR 3201.73 - Slide way lubricants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Slide way lubricants. 3201.73 Section 3201.73... Designated Items § 3201.73 Slide way lubricants. (a) Definition. Products used to provide lubrication and... this part, will give a procurement preference for qualifying biobased slide way lubricants. By...

  1. 7 CFR 3201.73 - Slide way lubricants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Slide way lubricants. 3201.73 Section 3201.73... Designated Items § 3201.73 Slide way lubricants. (a) Definition. Products used to provide lubrication and... this part, will give a procurement preference for qualifying biobased slide way lubricants. By...

  2. 7 CFR 3201.73 - Slide way lubricants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Slide way lubricants. 3201.73 Section 3201.73... Designated Items § 3201.73 Slide way lubricants. (a) Definition. Products used to provide lubrication and... this part, will give a procurement preference for qualifying biobased slide way lubricants. By...

  3. 21 CFR 864.3800 - Automated slide stainer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Automated slide stainer. 864.3800 Section 864.3800 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Automated slide stainer. (a) Identification. An automated slide stainer is a device used to stain...

  4. 21 CFR 864.3800 - Automated slide stainer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Automated slide stainer. 864.3800 Section 864.3800 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Automated slide stainer. (a) Identification. An automated slide stainer is a device used to stain...

  5. 21 CFR 864.3800 - Automated slide stainer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Automated slide stainer. 864.3800 Section 864.3800 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Automated slide stainer. (a) Identification. An automated slide stainer is a device used to stain...

  6. 21 CFR 864.3800 - Automated slide stainer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Automated slide stainer. 864.3800 Section 864.3800 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Automated slide stainer. (a) Identification. An automated slide stainer is a device used to stain...

  7. 21 CFR 864.3800 - Automated slide stainer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Automated slide stainer. 864.3800 Section 864.3800 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Automated slide stainer. (a) Identification. An automated slide stainer is a device used to stain...

  8. Experimental studies of compaction and dilatancy during frictional sliding on faults containing gouge

    USGS Publications Warehouse

    Morrow, C.A.; Byerlee, J.D.

    1989-01-01

    Transient strength changes are observed in fault gouge materials when the velocity of shearing is varied. A transient stress peak is produced when the strain rate in the gouge is suddenly increased, whereas a transient stress drop results from a sudden change to a slower strain rate. We have studied the mechanism responsible for these observations by performing frictional sliding experiments on sawcut granite samples filled with a layer of several different fault gouge types. Changes in pore volume and strength were monitored as the sliding velocity alternated between fast and slow rates. Pore volume increased at the faster strain rate, indicating a dilation of the gouge layer, whereas volume decreased at the slower rate indicating compaction. These results verify that gouge dilation is a function of strain rate. Pore volume changed until an equilibrium void ratio of the granular material was reached for a particular rate of strain. Using arguments from soil mechanics, we find that the dense gouge was initially overconsolidated relative to the equilibrium level, whereas the loose gouge was initially underconsolidated relative to this level. Therefore, the transient stress behavior must be due to the overconsolidated state of the gouge at the new rate when the velocity is increased and to the underconsolidated state when the velocity is lowered. Time-dependent compaction was also shown to cause a transient stress response similar to the velocity-dependent behavior. This may be important in natural fault gouges as they become consolidated and stronger with time. In addition, the strain hardening of the gouge during shearing was found to be a function of velocity, rendering it difficult to quantify the change in equilibrium shear stress when velocity is varied under certain conditions. ?? 1989.

  9. Distinguishing sediment waves from slope failure deposits: Field examples, including the 'humboldt slide', and modelling results

    USGS Publications Warehouse

    Lee, H.J.; Syvitski, J.P.M.; Parker, G.; Orange, Daniel L.; Locat, J.; Hutton, E.W.H.; Imran, J.

    2002-01-01

    Migrating sediment waves have been reported in a variety of marine settings, including submarine levee-fan systems, floors of fjords, and other basin or continental slope environments. Examination of such wave fields reveals nine diagnostic characteristics. When these characteristics are applied to several features previously attributed to submarine landslide deformation, they suggest that the features should most likely be reinterpreted as migrating sediment-wave fields. Sites that have been reinterpreted include the 'Humboldt slide' on the Eel River margin in northern California, the continental slope in the Gulf of Cadiz, the continental shelf off the Malaspina Glacier in the Gulf of Alaska, and the Adriatic shelf. A reassessment of all four features strongly suggests that numerous turbidity currents, separated by intervals of ambient hemipelagic sedimentation, deposited the wave fields over thousands of years. A numerical model of hyperpycnal discharge from the Eel River, for example, shows that under certain alongshore-current conditions, such events can produce turbidity currents that flow across the 'Humboldt slide', serving as the mechanism for the development of migrating sediment waves. Numerical experiments also demonstrate that where a series of turbidity currents flows across a rough seafloor (i.e. numerical steps), sediment waves can form and migrate upslope. Hemipelagic sedimentation between turbidity current events further facilitates the upslope migration of the sediment waves. Physical modelling of turbidity currents also confirms the formation and migration of seafloor bedforms. The morphologies of sediment waves generated both numerically and physically in the laboratory bear a strong resemblance to those observed in the field, including those that were previously described as submarine landslides.

  10. Studying the Effects of Nuclear Weapons Using a Slide-Rule Computer

    ERIC Educational Resources Information Center

    Shastri, Ananda

    2007-01-01

    This paper describes the construction of a slide-rule computer that allows one to quickly determine magnitudes of several effects that result from the detonation of a nuclear device. Suggestions for exercises are also included that allow high school and college-level physics students to explore scenarios involving these effects. It is hoped that…

  11. Vesicocutaneous fistula after sliding hernia repair

    PubMed Central

    Mittal, Varun; Kapoor, Rakesh; Sureka, Sanjoy

    2016-01-01

    Sliding inguinal hernias are usually direct inguinal hernias containing various abdominal viscera. The incidence of bladder forming a part of an inguinal hernia, called as “scrotal cystocele,” is 1–4%. The risk of bladder injury is as high as 12% when repairing this type of hernia. This case report emphasizes this aspect in a 65-year-old man who presented with urinary leak through the scrotal wound following right inguinal hernia repair. PMID:26941501

  12. Ultra High Pressure (UHP) Technology (BRIEFING SLIDES)

    DTIC Science & Technology

    2008-08-25

    AFRL-RX-TY-TP-2008-4600 POSTPRINT ULTRA HIGH PRESSURE ( UHP ) TECHNOLOGY (BRIEFING SLIDES) Patrick D. Sullivan Air Force Research...Since the discovery of the unprecedented effectiveness of 1500 psi Ultra High Pressure ( UHP ) technology in September of 2002 , AFRL scientists and... engineers have sought to increase Aircraft Rescue Fire Fighting (ARFF) performance by moving to higher flow rates to obtain greater throw distance and

  13. Let me entertain ... er ... teach you: gaining attention through the use of slide shows.

    PubMed

    Gigliotti, E

    1995-01-01

    The lecture method has been and continues to be the object of criticism. But, perhaps, it is not the lecture which should bear the brunt of the criticism, but rather the lecturer. All too often the audience is bored. This article examines several popular media currently used to enliven the lecture. Instructional design theory is used to discuss their limitations. The use of a self-assembled slide show, featuring novelty and humor, is advocated in order to assist the lecturer in gaining attention and, thereby, avoiding the boredom pitfall. Useful suggestions for developing a slide presentation are provided.

  14. Steady and transient sliding under rate-and-state friction

    NASA Astrophysics Data System (ADS)

    Putelat, Thibaut; Dawes, Jonathan H. P.

    2015-05-01

    The physics of dry friction is often modelled by assuming that static and kinetic frictional forces can be represented by a pair of coefficients usually referred to as μs and μk, respectively. In this paper we re-examine this discontinuous dichotomy and relate it quantitatively to the more general, and smooth, framework of rate-and-state friction. This is important because it enables us to link the ideas behind the widely used static and dynamic coefficients to the more complex concepts that lie behind the rate-and-state framework. Further, we introduce a generic framework for rate-and-state friction that unifies different approaches found in the literature. We consider specific dynamical models for the motion of a rigid block sliding on an inclined surface. In the Coulomb model with constant dynamic friction coefficient, sliding at constant velocity is not possible. In the rate-and-state formalism steady sliding states exist, and analysing their existence and stability enables us to show that the static friction coefficient μs should be interpreted as the local maximum at very small slip rates of the steady state rate-and-state friction law. Next, we revisit the often-cited experiments of Rabinowicz (J. Appl. Phys., 22:1373-1379, 1951). Rabinowicz further developed the idea of static and kinetic friction by proposing that the friction coefficient maintains its higher and static value μs over a persistence length before dropping to the value μk. We show that there is a natural identification of the persistence length with the distance that the block slips as measured along the stable manifold of the saddle point equilibrium in the phase space of the rate-and-state dynamics. This enables us explicitly to define μs in terms of the rate-and-state variables and hence link Rabinowicz's ideas to rate-and-state friction laws. This stable manifold naturally separates two basins of attraction in the phase space: initial conditions in the first one lead to the block

  15. Estimation of thermal loads on the VVER vessel under conditions of inversion of the stratified molten pool in a severe accident

    NASA Astrophysics Data System (ADS)

    Loktionov, V. D.; Mukhtarov, E. S.

    2016-09-01

    Analysis of the thermal state of molten pools that can be formed on the vessel bottom of the VVER-600 medium-power reactor during a severe anticipated accident with melting of the core is represented. Two types of the molten pool of core materials, with the two-layer and inverse three-layer stratification, are considered. Thermal loads acting on the reactor vessel from the melt are estimated depending on its formation time. Features of the thermal state of the melt in the case of its inverse stratification are analyzed. It is shown that thermal loads on the reactor vessel exceed the critical heat flux (CHF) when forming the two-layer stratified molten pool 10 and 24 h after its shutdown, and the thermal load is close to the corresponding CHF or somewhat exceeds it in 72 h. In the case of the formation of the inverse structure of the melt, one can observe a decrease by more than 2.5 times (in comparison with the two-layer stratified structure) in the thermal load on the reactor vessel in the region of its contact with the upper layer of the steel melt. Analysis of results showed that maximum densities of heat flux to the reactor vessel from the bottom metallic layer with the melt inversion did not exceed corresponding CHFs 24 and 72 h after the reactor shutdown. Because the thermal load on the reactor vessel can be localized in the region of its bottom, where the CHF is relatively small, during the inverse stratification of the melt, there is a need to carry out further in-depth experimental and analytical investigations of conditions for formation of the stratified molten pool and to obtain corrected experimental CHFs for conditions and outlines of cooling the external surface of the VVER-600 vessel in a severe accident.

  16. Managing and Querying Whole Slide Images

    PubMed Central

    Wang, Fusheng; Oh, Tae W.; Vergara-Niedermayr, Cristobal; Kurc, Tahsin; Saltz, Joel

    2012-01-01

    High-resolution pathology images provide rich information about the morphological and functional characteristics of biological systems, and are transforming the field of pathology into a new era. To facilitate the use of digital pathology imaging for biomedical research and clinical diagnosis, it is essential to manage and query both whole slide images (WSI) and analytical results generated from images, such as annotations made by humans and computed features and classifications made by computer algorithms. There are unique requirements on modeling, managing and querying whole slide images, including compatibility with standards, scalability, support of image queries at multiple granularities, and support of integrated queries between images and derived results from the images. In this paper, we present our work on developing the Pathology Image Database System (PIDB), which is a standard oriented image database to support retrieval of images, tiles, regions and analytical results, image visualization and experiment management through a unified interface and architecture. The system is deployed for managing and querying whole slide images for In Silico brain tumor studies at Emory University. PIDB is generic and open source, and can be easily used to support other biomedical research projects. It has the potential to be integrated into a Picture Archiving and Communications System (PACS) with powerful query capabilities to support pathology imaging. PMID:22844574

  17. Managing and querying whole slide images

    NASA Astrophysics Data System (ADS)

    Wang, Fusheng; Oh, Tae W.; Vergara-Niedermayr, Cristobal; Kurc, Tahsin; Saltz, Joel

    2012-02-01

    High-resolution pathology images provide rich information about the morphological and functional characteristics of biological systems, and are transforming the field of pathology into a new era. To facilitate the use of digital pathology imaging for biomedical research and clinical diagnosis, it is essential to manage and query both whole slide images (WSI) and analytical results generated from images, such as annotations made by humans and computed features and classifications made by computer algorithms. There are unique requirements on modeling, managing and querying whole slide images, including compatibility with standards, scalability, support of image queries at multiple granularities, and support of integrated queries between images and derived results from the images. In this paper, we present our work on developing the Pathology Image Database System (PIDB), which is a standard oriented image database to support retrieval of images, tiles, regions and analytical results, image visualization and experiment management through a unified interface and architecture. The system is deployed for managing and querying whole slide images for In Silico brain tumor studies at Emory University. PIDB is generic and open source, and can be easily used to support other biomedical research projects. It has the potential to be integrated into a Picture Archiving and Communications System (PACS) with powerful query capabilities to support pathology imaging.

  18. Grain boundary sliding in wires with bamboo structure

    SciTech Connect

    Schneibel, J.H.; Petersen, G.F.

    1985-01-01

    Grain boundary sliding during the torsional creep deformation of austenitic stainless steel wires (Fe-15 wt % Cr-15 wt % Ni) with bamboo structures has been investigated. At 1100/sup 0/K, the sliding rate du/dt is approximately proportional to tau/sup 2.5/ where tau is the applied shear stress. Although Reading and Smith's (Phil. Mag. A, 51, 71 (1985)) model of lattice-dislocation grain boundary sliding has shortcomings, it predicts the observed sliding rates quite well. At sufficiently small grain sizes and low stresses, the observed nonlinear grain boundary sliding may inhibit diffusional creep.

  19. Slide Presentations as Speech Suppressors: When and Why Learners Miss Oral Information

    ERIC Educational Resources Information Center

    Wecker, Christof

    2012-01-01

    The objective of this study was to test whether information presented on slides during presentations is retained at the expense of information presented only orally, and to investigate part of the conditions under which this effect occurs, and how it can be avoided. Such an effect could be expected and explained either as a kind of redundancy…

  20. Information Comprehension from Longhand Notes and Slides in the Language Classroom

    ERIC Educational Resources Information Center

    Kiliçkaya, Ferit

    2016-01-01

    The aim of the study presented in this paper was to compare undergraduate students' information comprehension under conditions where they took notes in longhand during traditional lectures and lectures given through slides. A quasi-experimental approach was adopted to collect the data from 42 participants enrolled in a compulsory course at a state…

  1. The Summer Slide: What We Know and Can Do about Summer Learning Loss

    ERIC Educational Resources Information Center

    Alexander, Karl, Ed.; Pitcock, Sarah, Ed.; Boulay, Matthew C., Ed.

    2016-01-01

    This book is an authoritative examination of summer learning loss, featuring original contributions by scholars and practitioners at the forefront of the movement to understand--and stem--the "summer slide." The contributors provide an up-to-date account of what research has to say about summer learning loss, the conditions in low-income…

  2. The Influence of Interfacial Roughness on Fiber Sliding in Oxide Composites with La-Monazite Interphases

    NASA Technical Reports Server (NTRS)

    Davis, J. B.; Hay, R. S.; Marshall, D. B.; Morgan, P. E. D.; Sayir, A.; Gray, Hugh R. (Technical Monitor); Farmer, Serene C. (Technical Monitor)

    2002-01-01

    Room temperature debonding and sliding of La-Monazite coated fibers is assessed using a composite with a polycrystalline alumina matrix and fibers of several different single crystal (mullite, sapphire) and directionally solidified eutectic (Al2O3/Y3Al5O12 and Al2O3/Y-ZrO2) compositions. These fibers provide a range of residual stresses and interfacial roughnesses. Sliding occurred over a debond crack at the fiber-coating interface when the sliding displacement and surface roughness were relatively small. At large sliding displacements with relatively rough interfaces, the monazite coatings were deformed extensively by fracture, dislocations and occasional twinning, whereas the fibers were undamaged. Dense, fine-grained (10 nm) microstructures suggestive of dynamic recrystallization were also observed in the coatings. Frictional heating during sliding is assessed. The possibility of low temperature recrystallization is discussed in the light of the known resistance of monazite to radiation damage. The ability of La-Monazite to undergo plastic deformation relatively easily at low temperatures may be enabling for its use as a composite interface.

  3. Reliability of whole slide images as a diagnostic modality for renal allograft biopsies.

    PubMed

    Jen, Kuang-Yu; Olson, Jean L; Brodsky, Sergey; Zhou, Xin J; Nadasdy, Tibor; Laszik, Zoltan G

    2013-05-01

    The use of digital whole slide images (WSI) in the field of pathology has become feasible for routine diagnostic purposes and has become more prevalent in recent years. This type of technology offers many advantages but must show the same degree of diagnostic reliability as conventional glass slides. Several studies have examined this issue in various settings and indicate that WSI are a reliable method for diagnostic pathology. Since transplant pathology is a highly specialized field that requires not only accurate but rapid diagnostic evaluation of biopsy materials, this field may greatly benefit from the use of WSI. In this study, we assessed the reliability of using WSI compared to conventional glass slides in renal allograft biopsies. We examined morphologic features and diagnostic categories defined by the Banff 07 Classification of Renal Allograft Pathology as well as additional morphologic features not included in this classification scheme. We found that intraobserver scores, when comparing the use of glass slides versus WSI, showed substantial agreement for both morphologic features (κ = 0.68) and acute rejection diagnostic categories (κ = 0.74). Furthermore, interobserver reliability was comparable for morphologic features (κ = 0.44 [glass] vs 0.42 [WSI]) and acute rejection diagnostic categories (κ = 0.49 [glass] vs 0.51 [WSI]). These data indicate that WSI are as reliable as glass slides for the evaluation of renal allograft biopsies.

  4. Micro and Nano-structure Development and Multiscale Physics at Sliding Metal Interfaces

    SciTech Connect

    Rigney, David A.

    2005-03-07

    This report describes research on the response of ductile materials to extreme loading conditions and high strain rates during impact combined with sliding friction. The work is a collaboration among two groups at Los Alamos National Laboratory and a tribology research group at The Ohio State University. The work involves experimental work and computer simulations at both laboratories and continuum mechanics analysis at OSU. Results to date demonstrate the importance of vorticity and mechanical mixing near the sliding interface in the development of tribomaterial.

  5. Temporal and storage effects on ultra-low volume droplets of insecticides collected on Teflon-coated slides.

    PubMed

    Farooq, Muhammad; Lloyd, Aaron M; Estep, Alden S; Walker, Todd W; Hughes, Tony

    2013-12-01

    Use of microscope slides is the most commonly used method to field-assess the droplet spectrum of ultra-low volume (ULV) sprays. Due to absence of analysis facilities during military deployments, slides must be stored and shipped, and the impact of delays in processing and storage conditions on droplets is unknown. This study was designed to evaluate the effect of storage temperatures and duration on droplets on Teflon-coated slides. Treatments included BVA-13 mineral oil, Kontrol 30-30 (30% permethrin), and Fyfanon (96.5% malathion), 2 slide wrapping techniques (proper and improper), and 2 storage temperatures (23 and 45 degrees C), replicated 6 times. The same areas of a slide were measured at different times for 56-58 days using the DropVision droplet measurement system. Regardless of the wrapping technique, droplets of BVA-13, Fyfanon, and Kontrol 30-30 on slides stored at 45 degrees C reduced significantly after 1, 2, and 1 day, respectively, but droplets on slides stored at 23 degrees C were not significantly affected. The results of this study may assist vector control professionals to accurately interpret the droplet size and help in the effective dispersal of ULV-applied insecticides.

  6. Pronounced enhancement of glucocorticoid-induced gene expression following severe heat shock of heat-conditioned cells hints to intricate cell survival tactics.

    PubMed

    Mitsiou, Dimitra J; Florentin, Ida; Baki, Lia; Georgakopoulos, Anastasios; Alexis, Michael N

    2005-02-01

    We have previously reported that severe heat shock of HeLa cells stably transfected with a chloramphenicol acetyltransferase (CAT) gene, transcription of which is controlled by two glucocorticoid-responsive elements and a minimal promoter, pronouncedly enhanced glucocorticoid-induced CAT expression compared to that of non-heated cells, in spite of the glucocorticoid-receptor-mediated transcription of the gene being temporarily compromised by the shock. We now report that prolonged severe heat shock of properly heat-conditioned cells resulted in far more pronounced enhancement of glucocorticoid-induced CAT mRNA and protein expressions, in spite of a similar heat-induced loss of receptor-mediated CAT gene transcription. During recovery from the shock the hormonal activation of transcription exceeded that of non-heated cells. While CAT mRNA translation was restored appreciably later than CAT gene transcription, mRNA and protein expressions were thermally enhanced to a comparable extent, consistent with the integrity of CAT mRNA being preserved during recovery. CAT mRNA turnover was fully impaired during early recovery, suggesting that stabilisation of CAT mRNA as well as stimulation of the hormonal activation of CAT gene transcription account for the thermal enhancement of glucocorticoid-induced CAT expression. This data hint to cell survival tactics designed to safeguard high expression of genes of stress-enduring function.

  7. Dry sliding wear behavior of epoxy composite reinforced with short palmyra fibers

    NASA Astrophysics Data System (ADS)

    Biswal, Somen; Satapathy, Alok

    2016-02-01

    The present work explores the possibility of using palmyra fiber as a replacement for synthetic fiber in conventional polymer composites for application against wear. An attempt has been made in this work to improve the sliding wear resistance of neat epoxy by reinforcing it with short palmyra fibers (SPF). Epoxy composites with different proportions (0, 4, 8 and 12 wt. %) of SPF are fabricated by conventional hand lay-up technique. Dry sliding wear tests are performed on the composite samples using a pin-on-disc test rig as per ASTM G 99-05 standards under various operating parameters. Design of experiment approach based on Taguchi's L16 Orthogonal Arrays is used for the analysis of the wear. This parametric analysis reveals that the SPF content is the most significant factor affecting the wear process followed by the sliding velocity. The sliding wear behavior of these composites under an extensive range of test conditions is predicted by a model based on the artificial neural network (ANN). A well trained ANN has been used to predict the sliding wear response of epoxy based composites over a wide range.

  8. Fluid pressure responses for a Devil's Slide-like system: problem formulation and simulation

    USGS Publications Warehouse

    Thomas, Matthew A.; Loague, Keith; Voss, Clifford I.

    2015-01-01

    This study employs a hydrogeologic simulation approach to investigate subsurface fluid pressures for a landslide-prone section of the central California, USA, coast known as Devil's Slide. Understanding the relative changes in subsurface fluid pressures is important for systems, such as Devil's Slide, where slope creep can be interrupted by episodic slip events. Surface mapping, exploratory core, tunnel excavation records, and dip meter data were leveraged to conceptualize the parameter space for three-dimensional (3D) Devil's Slide-like simulations. Field observations (i.e. seepage meter, water retention, and infiltration experiments; well records; and piezometric data) and groundwater flow simulation (i.e. one-dimensional vertical, transient, and variably saturated) were used to design the boundary conditions for 3D Devil's Slide-like problems. Twenty-four simulations of steady-state saturated subsurface flow were conducted in a concept-development mode. Recharge, heterogeneity, and anisotropy are shown to increase fluid pressures for failure-prone locations by up to 18.1, 4.5, and 1.8% respectively. Previous estimates of slope stability, driven by simple water balances, are significantly improved upon with the fluid pressures reported here. The results, for a Devil's Slide-like system, provide a foundation for future investigations

  9. HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α–induced excessive erythropoiesis

    PubMed Central

    Franke, Kristin; Kalucka, Joanna; Mamlouk, Soulafa; Singh, Rashim Pal; Muschter, Antje; Weidemann, Alexander; Iyengar, Vasuprada; Jahn, Steffen; Wieczorek, Kathrin; Geiger, Kathrin; Muders, Michael; Sykes, Alex M.; Poitz, David M.; Ripich, Tatsiana; Otto, Teresa; Bergmann, Sybille; Breier, Georg; Baretton, Gustavo; Fong, Guo-Hua; Greaves, David R.; Bornstein, Stefan; Chavakis, Triantafyllos; Fandrey, Joachim; Gassmann, Max

    2013-01-01

    Erythropoiesis must be tightly balanced to guarantee adequate oxygen delivery to all tissues in the body. This process relies predominantly on the hormone erythropoietin (EPO) and its transcription factor hypoxia inducible factor (HIF). Accumulating evidence suggests that oxygen-sensitive prolyl hydroxylases (PHDs) are important regulators of this entire system. Here, we describe a novel mouse line with conditional PHD2 inactivation (cKO P2) in renal EPO producing cells, neurons, and astrocytes that displayed excessive erythrocytosis because of severe overproduction of EPO, exclusively driven by HIF-2α. In contrast, HIF-1α served as a protective factor, ensuring survival of cKO P2 mice with HCT values up to 86%. Using different genetic approaches, we show that simultaneous inactivation of PHD2 and HIF-1α resulted in a drastic PHD3 reduction with consequent overexpression of HIF-2α-related genes, neurodegeneration, and lethality. Taken together, our results demonstrate for the first time that conditional loss of PHD2 in mice leads to HIF-2α–dependent erythrocytosis, whereas HIF-1α protects these mice, providing a platform for developing new treatments of EPO-related disorders, such as anemia. PMID:23264599

  10. Sliding Seal Materials for Adiabatic Engines, Phase 2

    NASA Technical Reports Server (NTRS)

    Lankford, J.; Wei, W.

    1986-01-01

    An essential task in the development of the heavy-duty adiabatic diesel engine is identification and improvements of reliable, low-friction piston seal materials. In the present study, the sliding friction coefficients and wear rates of promising carbide, oxide, and nitride materials were measured under temperature, environmental, velocity, and loading conditions that are representative of the adiabatic engine environment. In addition, silicon nitride and partially stabilized zirconia disks were ion implanted with TiNi, Ni, Co, and Cr, and subsequently run against carbide pins, with the objective of producing reduced friction via solid lubrication at elevated temperature. In order to provide guidance needed to improve materials for this application, the program stressed fundamental understanding of the mechanisms involved in friction and wear. Electron microscopy was used to elucidate the micromechanisms of wear following wear testing, and Auger electron spectroscopy was used to evaluate interface/environment interactions which seemed to be important in the friction and wear process. Unmodified ceramic sliding couples were characterized at all temperatures by friction coefficients of 0.24 and above. The coefficient at 800 C in an oxidizing environment was reduced to below 0.1, for certain material combinations, by the ion implanation of TiNi or Co. This beneficial effect was found to derive from lubricious Ti, Ni, and Co oxides.

  11. Buckling of a Flexible Strip Sliding on a Frictional Base

    NASA Astrophysics Data System (ADS)

    Huynen, Alexandre; Marck, Julien; Denoel, Vincent; Detournay, Emmanuel

    2013-03-01

    The main motivation for this contribution is the buckling of a drillstring sliding on the bottom of the horizontal section of borehole. The open questions that remain today are related to the determination of the onset of instability, and to the conditions under which different modes of constrained buckling occur. In this presentation, we are concerned by a two-dimensional version of this problem; namely, the sliding of a flexible strip being fed inside a conduit. The ribbon, which has a flexural rigidity EI and a weight per unit length w, is treated as an inextensible elastica of negligible thickness. The contact between the ribbon and the wall of the conduit is characterized by a friction coefficient μ. First, we report the result of a stability analysis that aims at determining the critical inserted length of the ribbon l* (μ) (scaled by the characteristic length λ =(EI / w) 1 / 3) at which there is separation between the strip and the conduit bottom, as well as the buckling mode. Next, the relationship between the feeding force F and the inserted length l after bifurcation is computed. Finally, the results of a ``kitchen table'' experiment involving a strip of silicon rubber being pushed on a plank are reported and compared with predictions.

  12. Computer generated slides: a need to curb our enthusiasm.

    PubMed

    Dalal, M D; Daver, B M

    1996-12-01

    The popular use of computer generated slides for presentations during plastic surgery scientific meetings has opened a fresh chapter in audiovisual techniques. Although the profusion of colours seen during presentations is a visual treat, the information imparted by these slides leaves much to be desired and raises the question of whether such attractive and apparently professionally made slides are visual aids during such presentations. Presentation slides are displayed for a very short time (10-15 seconds) as compared to slides displayed during a lecture and therefore these presentation slides should have the ability to impart their information very quickly. We conducted a study wherein 36 slides, each having a different colour combination, were displayed to a class of third year medical students who were asked to judge the efficacy of each slide. The attractiveness, clarity and recall of each slide was graded by every student and, with the information obtained, the most effective format and colour combinations to be used while making slides for presentations were established. We conclude that the best format for slides is a plain dark coloured background (blue, purple or green) and a separate, contrasting plain dark coloured title text background (red, green or purple), with white letters for the text and yellow letters for the title.

  13. Robust stabilization of underactuated nonlinear systems: A fast terminal sliding mode approach.

    PubMed

    Khan, Qudrat; Akmeliawati, Rini; Bhatti, Aamer Iqbal; Khan, Mahmood Ashraf

    2017-01-01

    This paper presents a fast terminal sliding mode based control design strategy for a class of uncertain underactuated nonlinear systems. Strategically, this development encompasses those electro-mechanical underactuated systems which can be transformed into the so-called regular form. The novelty of the proposed technique lies in the hierarchical development of a fast terminal sliding attractor design for the considered class. Having established sliding mode along the designed manifold, the close loop dynamics become finite time stable which, consequently, result in high precision. In addition, the adverse effects of the chattering phenomenon are reduced via strong reachability condition and the robustness of the system against uncertainties is confirmed theoretically. A simulation as well as experimental study of an inverted pendulum is presented to demonstrate the applicability of the proposed technique.

  14. Discrete-time sliding mode control for uncertain systems with state and input delays

    NASA Astrophysics Data System (ADS)

    Pai, Ming-Chang

    2010-12-01

    This article presents a discrete-time sliding mode control method for the robust stabilisation of linear uncertain multi-input discrete-time systems with state and input delays. The systems are assumed to have structured mismatched time-varying parameter uncertainties. A specified switching surface is proposed and a sliding mode controller is derived to ensure the existence of the quasi-sliding mode. Based on the improved Lyapunov function and linear matrix inequality technique, delay-independent sufficient conditions for the design of a stable switching surface are given and the stability of the overall closed-loop system is guaranteed. Neither chattering phenomenon will occur nor the knowledge of upper bound of uncertainties is required. Finally, simulation results demonstrate the efficacy of the proposed control methodology.

  15. Texturing in metals as a result of sliding

    NASA Technical Reports Server (NTRS)

    Wheeler, D. R.; Buckley, D. H.

    1975-01-01

    Sliding friction experiments were conducted with copper, nickel, iron and cobalt sliding on themselves in air and argon. The resulting wear surfaces were examined by X-ray analysis to determine if surface texturing had occurred as a result of sliding. Results of the investigation indicate that, for the face-centered-cubic metals copper and nickel, a (111) texture develops with the (111) planes tilted 10 deg in the direction of sliding. The body-centered-cubic metal iron exhibited a (110) texture with the (111) direction oriented in the direction of sliding. It also exhibited a 10 deg tilt in the direction of sliding. The environment influenced the results in that the degree of texture observed in argon was less than that seen in air for iron. No texturing was observed for the close-packed-hexagonal metal cobalt. Recrystallization was observed with copper as a result of sliding.

  16. Texturing in metals as a result of sliding

    NASA Technical Reports Server (NTRS)

    Wheeler, D. R.; Buckley, D. H.

    1973-01-01

    Sliding friction experiments were conducted with copper, nickel, iron, and cobalt sliding on themselves in air and argon. The resulting wear surfaces were examined with X-ray analysis to determine if surface texturing had occurred as a result of sliding. Results of the investigation indicate that, for the face-centered-cubic metals copper and nickel, a (111) texture develops with the (111) planes tilted 10 deg in the direction of sliding. The body-centered-cubic metal iron exhibited a (110) texture with the (100) direction oriented in the direction of sliding. It also exhibited a 10 deg tilt in the direction of sliding. The environment influenced the results in that the degree of texture observed in argon was less than that seen in air for iron. No texturing was observed for the close-packed-hexagonal metal cobalt. Recrystallization was observed with copper as a result of sliding.

  17. Slide-specific models for segmentation of differently stained digital histopathology whole slide images

    NASA Astrophysics Data System (ADS)

    Brieu, Nicolas; Pauly, Olivier; Zimmermann, Johannes; Binnig, Gerd; Schmidt, Günter

    2016-03-01

    The automatic analysis of whole slide images (WSIs) of stained histopathology tissue sections plays a crucial role in the discovery of predictive biomarkers in the field on immuno-oncology by enabling the quantification of the phenotypic information contained in the tissue sections. The automatic detection of cells and nuclei, while being one of the major steps of such analysis, remains a difficult problem because of the low visual differentiation of high pleomorphic and densely cluttered objects and of the diversity of tissue appearance between slides. The key idea of this work is to take advantage of well-differentiated objects in each slide to learn about the appearance of the tissue and in particular about the appearance of low-differentiated objects. We detect well-differentiated objects on a automatically selected set of representative regions, learn slide-specific visual context models, and finally use the resulting posterior maps to perform the final detection steps on the whole slide. The accuracy of the method is demonstrated against manual annotations on a set of differently stained images.

  18. Shallow translational slides hazard evaluation in Santa Marta de Penaguião (Douro valley - Portugal)

    NASA Astrophysics Data System (ADS)

    Pereira, Susana; Luís Zêzere, José; Bateira, Carlos

    2010-05-01

    The present study is developed for the municipality of Santa Marta de Penaguião (70 square kilometers), located in the Douro Valley region (Northern Portugal). In the past, several destructive landslides occurred in this area, and were responsible for deaths and destruction of houses and roads. Despite these losses, mitigation and landslide zonation programs are missing, and the land use planning at the municipal level did not solve yet the problem. The study area is mainly composed by metamorphic rocks (e.g., schist and quartzite). These rocks are strongly fractured, and weathered materials are abundant in clayed schist, mainly in those areas where agricultural terraces were constructed centuries ago for the vineyard monoculture. From the geomorphologic point of view, the study area is characterized by deep incised valleys, tectonic depressions and slopes controlled by the geological structure. Elevation ranges from 49 m to 1416 m. The main landslide triggering factor is rainfall and the mean annual precipitation ranges from 700 mm (in the bottom of fluvial valleys) to 2500 mm (in the mountains top). A landslide inventory was performed in 2005-2009 using aerial photo-interpretation (1/5.000 scale) and field work. The inventory includes 848 landslides, most of shallow translational slide type (85% of total slope movements). The landslide density is 10.5 events/square kilometers, and the average landslide area is 535 square meters. The susceptibility to shallow translational slide occurrence was assessed at the 1: 10 000 scale in a GIS environment. Two different bivariate statistical methods were used to evaluate landslide susceptibility: the Information Value and the Fuzzy Logic Gamma operator. Eight conditioning factors were weighted and integrated to model susceptibility: slope angle, slope aspect, slope curvature, lithology, geomorphologic units, fault density, land use and terrace structures build in slopes. The susceptibility results were validated using a

  19. Observational study on the concentration distributions of SO{sub 2} and NO{sub 2} in Dhaka, Bangladesh under severe air pollution condition in winter

    SciTech Connect

    Azad, A.K.; Kitada, T.

    1996-12-31

    Dhaka is the capital and the biggest city of Bangladesh, and is expanding very rapidly. Emissions from heavy traffic and many small industries and commercial complexes, newly developed in and around the city, are polluting the air of Dhaka city. The air pollution is severe especially in winter due to adverse meteorological conditions such as low wind speed and dry, stably-stratified air, which restricts the mixing height to low levels and prevent dispersion of pollutants. But so far no study of air pollution of Dhaka city has been done. We have first measured SO{sub 2} and NO{sub 2} concentrations in Dhaka city in a large scale and derived their spatial distributions over Dhaka. Molecular diffusion tubes, which do not require power sources and are produced at low cost, have been used to measure the concentration distributions of SO{sub 2} and NO{sub 2} at 64 sites in Dhaka city and its suburbs during the period of December-January of 1995-96. The diffusion tube samplers were calibrated using 6 automated air pollution monitoring stations in Aichi-prefecture, Japan. The calibration curve and the distribution of the concentration data acquired by automatic measurement instrument at each location showed that the error range of measurements with the molecular diffusion tube samplers was 2-27%. The samples were analyzed using ion-chromatography and spectrophotometer to determine the concentrations of SO{sub 2} and NO{sub 2} respectively. The contamination of unexposed tubes under field conditions was determined and the value of the blank test was subtracted from the measurements of the diffusion tube samplers. The effects of wind turbulence and temperature were reduced using polyflon filters.

  20. Effect of Elevated Atmospheric CO2 and Temperature on the Disease Severity of Rocket Plants Caused by Fusarium Wilt under Phytotron Conditions.

    PubMed

    Chitarra, Walter; Siciliano, Ilenia; Ferrocino, Ilario; Gullino, Maria Lodovica; Garibaldi, Angelo

    2015-01-01

    The severity of F. oxysporum f.sp. conglutinans on rocket plants grown under simulated climate change conditions has been studied. The rocket plants were cultivated on an infested substrate (4 log CFU g-1) and a non-infested substrate over three cycles. Pots were placed in six phytotrons in order to simulate different environmental conditions: 1) 400-450 ppm CO2, 18-22°C; 2) 800-850 ppm CO2, 18-22°C; 3) 400-450 ppm CO2, 22-26°C, 4) 800-850 ppm CO2, 22-26°C, 5) 400-450 ppm CO2, 26-30°C; 6) 800-850 ppm CO2, 26-30°C. Substrates from the infested and control samples were collected from each phytotron at 0, 60 and 120 days after transplanting. The disease index, microbial abundance, leaf physiological performances, root exudates and variability in the fungal profiles were monitored. The disease index was found to be significantly influenced by higher levels of temperature and CO2. Plate counts showed that fungal and bacterial development was not affected by the different CO2 and temperature levels, but a significant decreasing trend was observed from 0 up to 120 days. Conversely, the F. oxysporum f.sp. conglutinans plate counts did not show any significantly decrease from 0 up to 120 days. The fungal profiles, evaluated by means of polymerase chain reaction denaturing gradient gel electrophoresis (PCR-DGGE), showed a relationship to temperature and CO2 on fungal diversity profiles. Different exudation patterns were observed when the controls and infested plants were compared, and it was found that both CO2 and temperature can influence the release of compounds from the roots of rocket plants. In short, the results show that global climate changes could influence disease incidence, probably through plant-mediated effects, caused by soilborne pathogens.

  1. A comparative study of wave-current interactions over the eastern Canadian shelf under severe weather conditions using a coupled wave-circulation model

    NASA Astrophysics Data System (ADS)

    Wang, Pengcheng; Sheng, Jinyu

    2016-07-01

    A coupled wave-circulation model is used to examine interactions between surface gravity waves and ocean currents over the eastern Canadian shelf and adjacent deep waters during three severe weather events. The simulated significant wave heights (SWHs) and peak wave periods reveal the importance of wave-current interactions (WCI) during and after the storm. In two fast-moving hurricane cases, the maximum SWHs are reduced by more than 11% on the right-hand side of the storm track and increased by about 5% on the left-hand side due to different WCI mechanisms on waves on two sides of the track. The dominate mechanisms of the WCI on waves include the current-induced modification of wind energy input to the wave generation, and current-induced wave advection and refraction. In the slow-moving winter storm case, the effect of WCI decreases the maximum SWHs on both sides of the storm track due to different results of the current-induced wave advection, which is affected greatly by the storm translation speed. The simulated sea surface temperature (SST) cooling induced by hurricanes and SST warming induced by the winter storm are also enhanced (up to 1.2°C) by the WCI mechanisms on circulation and hydrography. The 3D wave forces can affect water columns up to 200 m in all three storm cases. By comparison, the effect of breaking wave-induced mixing in the ocean upper layer is more important under strong stratification conditions in two hurricane cases than under weak stratification conditions in the winter storm case.

  2. Effect of Elevated Atmospheric CO2 and Temperature on the Disease Severity of Rocket Plants Caused by Fusarium Wilt under Phytotron Conditions

    PubMed Central

    Chitarra, Walter; Siciliano, Ilenia; Ferrocino, Ilario; Gullino, Maria Lodovica; Garibaldi, Angelo

    2015-01-01

    The severity of F. oxysporum f.sp. conglutinans on rocket plants grown under simulated climate change conditions has been studied. The rocket plants were cultivated on an infested substrate (4 log CFU g-1) and a non-infested substrate over three cycles. Pots were placed in six phytotrons in order to simulate different environmental conditions: 1) 400–450 ppm CO2, 18–22°C; 2) 800–850 ppm CO2, 18–22°C; 3) 400–450 ppm CO2, 22–26°C, 4) 800–850 ppm CO2, 22–26°C, 5) 400–450 ppm CO2, 26–30°C; 6) 800–850 ppm CO2, 26–30°C. Substrates from the infested and control samples were collected from each phytotron at 0, 60 and 120 days after transplanting. The disease index, microbial abundance, leaf physiological performances, root exudates and variability in the fungal profiles were monitored. The disease index was found to be significantly influenced by higher levels of temperature and CO2. Plate counts showed that fungal and bacterial development was not affected by the different CO2 and temperature levels, but a significant decreasing trend was observed from 0 up to 120 days. Conversely, the F. oxysporum f.sp. conglutinans plate counts did not show any significantly decrease from 0 up to 120 days. The fungal profiles, evaluated by means of polymerase chain reaction denaturing gradient gel electrophoresis (PCR-DGGE), showed a relationship to temperature and CO2 on fungal diversity profiles. Different exudation patterns were observed when the controls and infested plants were compared, and it was found that both CO2 and temperature can influence the release of compounds from the roots of rocket plants. In short, the results show that global climate changes could influence disease incidence, probably through plant-mediated effects, caused by soilborne pathogens. PMID:26469870

  3. Towards slide enhancement with the titanium-molybdenum wire?

    PubMed

    Thiry, Pol; Barthélémi, Stéphane

    2010-12-01

    This study aims to improve the tribological properties of titanium-molybdenum wire. Following an analysis of the wire/bracket/ligation friction parameters and an overview of the technological research into means of reducing such friction,we set up several types of surface treatment in the laboratory by physical deposition in the vapor phase and using cold plasma technology. The specimens obtained underwent two types of tribological tests and were then subjected to traction and bending tests in order to determine the variations in their mechanical properties induced by the different types of treatment. For purposes of comparison, all the tests were conducted on untreated wire, TMA® Low-friction® wire and stainless steel wire and with two types of elastomeric ties. We were able to demonstrate some remarkable slide performances obtained using cold plasma nitriding while preserving the mechanical properties. A significant difference was observed relative to the other surface treatments.

  4. Sliding contacts on printed circuit boards and wear behavior

    NASA Astrophysics Data System (ADS)

    Le Solleu, J.-P.

    2010-04-01

    Automotive suppliers use since decades printed circuit boards (PCB) gold plating pads, as direct contact interface for low current sliding contacts. Several gold plating processes are available on the market, providing various wear behaviour. Some specific galvanic hard gold (AuCo or AuNi). plating was developed on PCB's. This specific plating generates extra costs due to the material quantity and also the process complexity. In a cost driven industry, the challenge is to use a standard low cost PCB for systems requesting high reliability performances. After a brief overview of standard PCB manufacturing processes and especially gold plating processes, the global experimental results of wear behaviour of three different gold plating technologies will be exposed and an explanation of the correlation between surface key parameters and wear out will be provided.

  5. Sliding Contact Bearings for Service to 700 C

    NASA Technical Reports Server (NTRS)

    Sliney, Harold E.

    1996-01-01

    Cylindrical, sliding contact bearings made entirely of a self-lubricating powder metallurgy composite (PM212) or of super alloy shells lined with clad PM212 were tested in an oscillating mode at temperatures from 25 to 700 C. Tests of 100 hr duration or longer were conducted at a bearing unit load of 3.45 Mpa (500 psi). Shorter duration tests at various unit loads up to 24.1 Mpa (3500 psi) were also conducted. In comparison tests, bearings lubricated with PM212 had superior anti-wear characteristics compared to the baseline, unlubricated, super alloy bearings: no galling of PM212-lubricated bearings occurred, while severe surface damage including galling occurred, especially at high loads, during the baseline tests. A heat treatment procedure, which dimensionally stabilizes PM212 and thereby minimizes clearance changes during high temperature bearing operation, is described.

  6. ANDES TOOLS: Promotional slides for Industrial Clients

    DTIC Science & Technology

    2015-09-03

    Briefing Charts 3. DATES COVERED (From - To) 10 August 2015 – 3 September 2015 4. TITLE AND SUBTITLE ANDES TOOLS: Promotional slides for Industrial ...Clients 5a. CONTRACT NUMBER FA9300-13-C-2014 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Tim Holmes, D.Sc. 5d. PROJECT NUMBER 5e. TASK... Industrial Clients PA Case Number: #15479; Clearance Date: 9/3/2015 14. ABSTRACT Briefing Charts/Viewgraphs 15. SUBJECT TERMS N/A 16. SECURITY

  7. Collective sliding states for colloidal molecular crystals

    SciTech Connect

    Reichhardt, Charles; Reichhardt, Cynthia

    2008-01-01

    We study the driving of colloidal molecular crystals over periodic substrates such as those created with optical traps. The n-merization that occurs in the colloidal molecular crystal states produces a remarkably rich variety of distinct dynamical behaviors, including polarization effects within the pinned phase and the formation of both ordered and disordered sliding phases. Using computer simulations, we map the dynamic phase diagrams as a function of substrate strength for dimers and trimers on a triangular substrate, and correlate features on the phase diagram with transport signatures.

  8. Bi-directional planar slide mechanism

    DOEpatents

    Bieg, Lothar F.

    2003-11-04

    A bi-directional slide mechanism. A pair of master and slave disks engages opposite sides of the platform. Rotational drivers are connected to master disks so the disks rotate eccentrically about their respective axes of rotation. Opposing slave disks are connected to master disks on opposite sides of the platform by a circuitous mechanical linkage, or are electronically synchronized together using stepper motors, to effect coordinated motion. The synchronized eccentric motion of the pairs of master/slave disks compels smooth linear motion of the platform forwards and backwards without backlash. The apparatus can be incorporated in a MEMS device.

  9. Corrosion behavior of several metals in ethylene glycol-base heat-transfer fluids under conditions encountered in solar energy systems

    SciTech Connect

    Zeman, G.J.

    1980-01-01

    The corrosion behavior of aluminum, copper, and iron in inhibited ethylene glycol-ASTM corrosive water solutions was evaluated in a laboratory loop under isothermal and heat-flux conditions for 1000 h at temperatures between 378 and 413/sup 0/K, in static autoclave tests at 450/sup 0/K for 500 h, and by potentiodynamic polarization measurements at temperatures between 298 and 348/sup 0/K. The effect of time, temperature, and ethylene glycol concentration of the heat-transfer fluid on the extent of inhibitor depletion was determined from analyses of the reserve alkalinity, pH, and inhibitor content of the solutions. The performance of an electrochemical sensor as a monitor of fluid quality was also evaluated. A heat flux of 0.4 to 1.0 kW/m/sup 2/ did not have a significant effect on the corrosion behavior of the various materials at temperatures between 378 and 413/sup 0/K. The corrosion rates of aluminum, copper, and iron in the 50 volume percent inhibited ethylene glycol-corrosive water solution decreased as a function of time during the 1000-h test. At 413/sup 0/K, the corrosion rate of copper was considerably higher than that of iron or aluminum at low flow velocity. Significant degradation of the fluid quality, as indicated by the measurement of the pH, reserve alkalinity, and inhibitor concentrations, occurred after several hundred hours at temperatures of approx. 450/sup 0/K.

  10. A series of abnormal climatic conditions caused the most severe outbreak of first-generation adults of the meadow moth ( Loxostege sticticalis L.) in China

    NASA Astrophysics Data System (ADS)

    Chen, Xiao; Zeng, Juan; Zhai, Baoping

    2016-06-01

    The meadow moth, Loxostege sticticalis L., is a destructive migratory pest in the northern temperate zone. The outbreak mechanism of first-generation adults in China remains unclear. In 2008, the density of first-generation larvae was very low or even negligible in most sites in China. However, a great number of first-generation adults appeared unexpectedly in late July, and their offspring caused the most severe infestation on record. The present study aims to determine where the large influx of immigrant adults originated from and how this unprecedented population was established. Source areas were explored by trajectory analysis, and climatic patterns related to the population increase were investigated. Results showed that the outbreak population mainly immigrated from Northeast Mongolia and the Chita State of Russia, and the buildup of such a large population could be attributed to an exceptional northward migration of overwintered adults from North China to East Mongolia in the spring of 2007 and unusually favourable climatic conditions in the next two growth seasons. These results indicated that the population dynamics of meadow moth in Northeast Asia would be difficult to predict when only considering local climatic factors and population size within one country. International joint monitoring and information sharing related to this pest between China, Mongolia and Russia should be implemented.

  11. Simulations of contact angle induced pearling for sliding drops

    NASA Astrophysics Data System (ADS)

    McCue, Scott; Mayo, Lisa; Moroney, Timothy

    2015-11-01

    Droplets sliding down an incline can develop a corner or a cusp at their rear, or undergo a pearling transition whereby the tail breaks up into a number of smaller satellite droplets. These phenomena have been of interest since the experimental work of. It appears that the experimental investigation of this problem is limited due to the inherent difficulty of minimising contact angle hysteresis, whereby physical or chemical heterogeneities of the substrate cause pinning and distortion of the droplet. By applying a lubrication model with a disjoining pressure term, we investigate these flows numerically in order to further shed light on how certain conditions (such as contact angle) affect the corner-cusp-pearling transition. We acknowledge support from the ARC Linkage Project LP100200476.

  12. LETTER TO THE EDITOR: No sliding in time

    NASA Astrophysics Data System (ADS)

    Shtengel, Kirill; Nayak, Chetan; Bishara, Waheb; Chamon, Claudio

    2005-09-01

    In this letter, we analyse the following apparent paradox: as has been recently proved by Hastings (2004 Phys. Rev. 69 104431), under a general set of conditions, if a local Hamiltonian has a spectral gap above its (unique) ground state (GS), all connected equal-time correlation functions of local operators decay exponentially with distance. On the other hand, statistical mechanics provides us with examples of 3D models displaying so-called sliding phases (O'Hern et al 1999 Phys. Rev. Lett. 83 2745) which are characterized by the algebraic decay of correlations within 2D layers and exponential decay in the third direction. Interpreting this third direction as time would imply a gap in the corresponding (2+1)D quantum Hamiltonian which would seemingly contradict Hastings' theorem. The resolution of this paradox lies in the non-locality of such a quantum Hamiltonian.

  13. Application of Sliding Mode Methods to the Design of Reconfigurable Flight Control Systems

    NASA Technical Reports Server (NTRS)

    Wells, Scott R.

    2002-01-01

    Observer-based sliding mode control is investigated for application to aircraft reconfigurable flight control. A comprehensive overview of reconfigurable flight control is given, including, a review of the current state-of-the-art within the subdisciplines of fault detection, parameter identification, adaptive control schemes, and dynamic control allocation. Of the adaptive control methods reviewed, sliding mode control (SMC) appears very promising due its property of invariance to matched uncertainty. An overview of sliding mode control is given and its remarkable properties are demonstrated by example. Sliding mode methods, however, are difficult to implement because unmodeled parasitic dynamics cause immediate and severe instability. This presents a challenge for all practical applications with limited bandwidth actuators. One method to deal with parasitic dynamics is the use of an asymptotic observer in the feedback path. Observer-based SMC is investigated, and a method for selecting observer gains is offered. An additional method for shaping the feedback loop using a filter is also developed. It is shown that this SMC prefilter is equivalent to a form of model reference hedging. A complete design procedure is given which takes advantage of the sliding mode boundary layer to recast the SMC as a linear control law. Frequency domain loop shaping is then used to design the sliding manifold. Finally, three aircraft applications are demonstrated. An F-18/HARV is used to demonstrate a SISO pitch rate tracking controller. It is also used to demonstrate a MIMO lateral-directional roll rate tracking controller. The last application is a full linear six degree-of-freedom advanced tailless fighter model. The observer-based SMC is seen to provide excellent tracking with superior robustness to parameter changes and actuator failures.

  14. Application of sliding mode methods to the design of reconfigurable flight control systems

    NASA Astrophysics Data System (ADS)

    Wells, Scott Russell

    Observer-based sliding mode control is investigated for application to aircraft reconfigurable flight control. A comprehensive overview of reconfigurable flight control is given, including a review of the current state-of-the-art within the subdisciplines of fault detection, parameter identification, adaptive control schemes, and dynamic control allocation. Of the adaptive control methods reviewed, sliding mode control (SMC) appears very promising due its property of invariance to matched uncertainty. An overview of sliding mode control is given and its remarkable properties are demonstrated by example. Sliding mode methods, however, are difficult to implement because unmodeled parasitic dynamics cause immediate and severe instability. This presents a challenge for all practical applications with limited bandwidth actuators. One method to deal with parasitic dynamics is the use of an asymptotic observer in the feedback path. Observer-based SMC is investigated, and a method for selecting observer gains is offered. An additional method for shaping the feedback loop using a filter is also developed. It is shown that this SMC prefilter is equivalent to a form of model reference hedging. A complete design procedure is given which takes advantage of the sliding mode boundary layer to recast the SMC as a linear control law. Frequency domain loop shaping is then used to design the sliding manifold. Finally, three aircraft applications are demonstrated. An F-18/HARV is used to demonstrate a SISO pitch rate tracking controller. It is also used to demonstrate a MIMO lateral-directional roll rate tracking controller. The last application is a full linear six degree-of-freedom advanced tailless fighter model. The observer-based SMC is seen to provide excellent tracking with superior robustness to parameter changes and actuator failures.

  15. Submarine slumps, slides, and flows dominate sculpting of Beringian Margin, Alaska

    SciTech Connect

    Carlson, P.R.; Karl, H.A.; Edwards, B.D.; Gardner, J.V.; Hall, R. )

    1990-06-01

    The 1,400 km long Beringian margin is characterized by several very large submarine canyons and by a large oceanic plateau at the southern end. GLORIA sidescan-sonar imagery provides a perspective of this margin that is unattainable with conventional acoustic profiles. The broad coverage of GLORIA images emphasizes that, of all the sedimentary processes affecting this vast margin, mass movement is clearly the dominant shaping process. Styles of failure include mud and debris flows, slumps, and massive block slides, some covering areas greater than 1,500 km{sup 2}. GLORIA imagery and seismic-reflection profiles show evidence for a wide variety of slides and slumps in the canyons of the northern margin, Navarin and Pervenets. The 100 km long shelf edge between these two canyons is characterized by a series of scalloped slide scars and incipient scars associated with blocks of sedimentary material, 1 to 2 km across. One of the largest single slide masses is a huge block tens of kilometers wide that occurs on the rise in the central part of the margin beyond the mouth of Zhemchug Canyon. Sliding of this block may have initiated the incision of the world's largest submarine canyon. The removal of this block accelerated headward erosion by retrograde failure until Zhemchug Canyon was cut back to a fault parallel to the shelf edge. Mass movement along the southern margin is widespread at the edges of Umnak Plateau. One mass failure, well-defined by GLORIA, is about 30 km wide and 55 km long. This and other slides along the plateau are associated with diapiric-like structures, suggesting relatively recent tectonism.

  16. An investigation of rolling-sliding contact fatigue damage of carburized gear steels

    NASA Astrophysics Data System (ADS)

    Kramer, Patrick C.

    The goal of this study was to evaluate the differences in RSCF performance between vacuum and gas carburized steels as well as to investigate the evolution of damage (wear and microstructure changes) leading to pitting. Vacuum and gas carburizing was performed on two gear steels (4120 and 4320) at 1010°C. The carburized specimens were tested in the as-carburized condition using a RSCF machine designed and built at the Colorado School of Mines. The tests were conducted at 3.2 GPa nominal Hertzian contact stress, based on pure rolling, 100°C, and using a negative twenty percent slide ratio. Tests were conducted to pitting failure for each condition for a comparison of the average fatigue lives. Pure rolling tests were also conducted, and were suspended at the same number of cycles as the average RSCF life for a comparison of fatigue damage developed by RCF and RSCF. Incremental tests were suspended at 1,000, 10,000, 100,000, and 200,000 cycles for the vacuum carburized steels to evaluate the wear and damage developed during the initial cycles of RSCF testing and to relate the wear and damage to pitting resistance. Incremental damage was not investigated for gas carburizing due to the limited number of available specimens. The vacuum carburized samples showed a decreased pitting fatigue resistance over the gas carburized samples, possibly due to the presence of bainite in the vacuum carburized cases. Pitting was observed to initiate from surface micropitting and microcracking. A microstructural change induced by contact fatigue, butterflies, was shown to contribute to micropitting and microcracking. Incremental testing revealed that the formation of a microcrack preceded and was necessary for the formation of the butterfly features, and that the butterfly features developed between 10,000 and 100,000 cycles. The orientation and depth of butterfly formation was shown to be dependent upon the application of traction stresses from sliding. RSCF butterflies formed

  17. Using slides to test for changes in crown defoliation assessment methods. Part I: Visual assessment of slides.

    PubMed

    Dobbertin, Matthias; Hug, Christian; Mizoue, Nobuya

    2004-11-01

    In this study we used photographs of tree crowns to test whether the assessment methods for tree defoliation in Switzerland have changed over time. We randomly selected 24 series of slides of Norway spruce with field assessments made between 1986 and 1995. The slides were randomly arranged and assessed by three experts without prior knowledge of the year when the slide was taken or the tree number. Defoliation was assessed using the Swiss reference photo guide. Although the correlations between the field assessments and slide assessments were high (Spearman's rank correlation coefficient ranged between 0.79 and 0.83), we found significant differences between field and slide assessments (4.3 to 9% underprediction by the slide assessors) and between the slide assessments. However, no significant trends in field assessment methods could be detected. When the mean differences between field and slide assessments were subtracted, in some years, field assessors consistently underpredicted (1990, 1992) or overpredicted defoliation (1987, 1991). Defoliation tended to be overpredicted in slides taken against the light, and underpredicted for trees with more than 25% crown overlap. We conclude that slide series can be used to detect changes in assessment methods. However, potential observer bias calls for more objective methods of assessment.

  18. Existence and Modulation of Uniform Sliding States in Driven and Overdamped Particle Chains

    NASA Astrophysics Data System (ADS)

    Qin, Wen-Xin

    2012-04-01

    In this paper we are mainly concerned with existence and modulation of uniform sliding states for particle chains with damping γ and external driving force F. If the on-site potential vanishes, then for each F > 0 there exist trivial uniform sliding states x n ( t) = n ω + ν t + α for which the particles are uniformly spaced with spacing ω > 0, the sliding velocity of each particle is ν = F/ γ, and the phase α is arbitrary. If the particle chain with convex interaction potential is placed in a periodic on-site potential, we show under some conditions the existence of modulated uniform sliding states of the form x_n(t)=nω+ν t+α+u(nω+ν t+α), where the modulation function u is periodic and unique up to phase. The conditions are that the system is overdamped and the driving force F exceeds some critical value F d ( ω) ≥ 0 depending on mean spacing ω. If {Fin [0,F_d(ω)]} , the system possesses a set of rotationally ordered equilibrium states for irrational ω, which can be described by a non-decreasing hull function, just as the case γ = F = 0, where Aubry-Mather theory applies to ground states. Meanwhile, we prove that F d ( ω) = 0, which was argued physically much earlier, if the hull function of ground states with irrational rotation number ω for F = 0 is continuous.

  19. Presentation video retrieval using automatically recovered slide and spoken text

    NASA Astrophysics Data System (ADS)

    Cooper, Matthew

    2013-03-01

    Video is becoming a prevalent medium for e-learning. Lecture videos contain text information in both the presentation slides and lecturer's speech. This paper examines the relative utility of automatically recovered text from these sources for lecture video retrieval. To extract the visual information, we automatically detect slides within the videos and apply optical character recognition to obtain their text. Automatic speech recognition is used similarly to extract spoken text from the recorded audio. We perform controlled experiments with manually created ground truth for both the slide and spoken text from more than 60 hours of lecture video. We compare the automatically extracted slide and spoken text in terms of accuracy relative to ground truth, overlap with one another, and utility for video retrieval. Results reveal that automatically recovered slide text and spoken text contain different content with varying error profiles. Experiments demonstrate that automatically extracted slide text enables higher precision video retrieval than automatically recovered spoken text.

  20. Sliding viscoelastic drops on slippery surfaces

    NASA Astrophysics Data System (ADS)

    Xu, H.; Clarke, A.; Rothstein, J. P.; Poole, R. J.

    2016-06-01

    We study the sliding of drops of constant-viscosity dilute elastic liquids (Boger fluids) on various surfaces caused by sudden surface inclination. For smooth or roughened hydrophilic surfaces, such as glass or acrylic, there is essentially no difference between these elastic liquids and a Newtonian comparator fluid (with identical shear viscosity, surface tension, and static contact angle). In contrast for embossed polytetrafluoroethylene superhydrophobic surfaces, profound differences are observed: the elastic drops slide at a significantly reduced rate and complex branch-like patterns are left on the surface by the drop's wake including, on various scales, beads-on-a-string like phenomena. Microscopy images indicate that the strong viscoelastic effect is caused by stretching filaments of fluid from isolated islands, residing at pinning sites on the surface pillars, of the order ˜30 μm in size. On this scale, the local strain rates are sufficient to extend the polymer chains, locally increasing the extensional viscosity of the solution, retarding the drop and leaving behind striking branch-like structures on much larger scales.

  1. Markov state modeling of sliding friction.

    PubMed

    Pellegrini, F; Landes, François P; Laio, A; Prestipino, S; Tosatti, E

    2016-11-01

    Markov state modeling (MSM) has recently emerged as one of the key techniques for the discovery of collective variables and the analysis of rare events in molecular simulations. In particular in biochemistry this approach is successfully exploited to find the metastable states of complex systems and their evolution in thermal equilibrium, including rare events, such as a protein undergoing folding. The physics of sliding friction and its atomistic simulations under external forces constitute a nonequilibrium field where relevant variables are in principle unknown and where a proper theory describing violent and rare events such as stick slip is still lacking. Here we show that MSM can be extended to the study of nonequilibrium phenomena and in particular friction. The approach is benchmarked on the Frenkel-Kontorova model, used here as a test system whose properties are well established. We demonstrate that the method allows the least prejudiced identification of a minimal basis of natural microscopic variables necessary for the description of the forced dynamics of sliding, through their probabilistic evolution. The steps necessary for the application to realistic frictional systems are highlighted.

  2. Markov state modeling of sliding friction

    NASA Astrophysics Data System (ADS)

    Pellegrini, F.; Landes, François P.; Laio, A.; Prestipino, S.; Tosatti, E.

    2016-11-01

    Markov state modeling (MSM) has recently emerged as one of the key techniques for the discovery of collective variables and the analysis of rare events in molecular simulations. In particular in biochemistry this approach is successfully exploited to find the metastable states of complex systems and their evolution in thermal equilibrium, including rare events, such as a protein undergoing folding. The physics of sliding friction and its atomistic simulations under external forces constitute a nonequilibrium field where relevant variables are in principle unknown and where a proper theory describing violent and rare events such as stick slip is still lacking. Here we show that MSM can be extended to the study of nonequilibrium phenomena and in particular friction. The approach is benchmarked on the Frenkel-Kontorova model, used here as a test system whose properties are well established. We demonstrate that the method allows the least prejudiced identification of a minimal basis of natural microscopic variables necessary for the description of the forced dynamics of sliding, through their probabilistic evolution. The steps necessary for the application to realistic frictional systems are highlighted.

  3. A Crossed Sliding Luttinger Liquid phase

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, Ranjan; Kane, C. L.; Lubensky, T. C.

    2001-03-01

    It was recently demonstrated [1] that a stack of weakly coupled 2D planar XY-models can exhibit a sliding phase characterized by correlations that die off as a power-law with distance within a plane and exponentially with distance in the perpendicular direction. In this talk we investigate how these ideas can be extended to two-dimensional arrays of coupled quantam wires. In particular, we will focus on a crossed array of wires and demonstrate the existence of the so-called "crossed sliding Luttinger liquid" phase [2]. This phase is characterized by power-law correlations, and a two-dimensional isotropic in-plane conductivity that diverges as a power-law in temperature T as T goes to 0. It thus represents a nearly isotropic non-Fermi liquid state in two dimensions. 1. C.S. O'Hern, T.C. Lubensky, and J.Toner, Phys. Rev. Lett. 83, 2745 (1999). 2. Ranjan Mukhopadhyay, C.L. Kane, and T.C. Lubensky, condmat/0007039.

  4. Energy Partitioning during Frictional Sliding at Coseismic Slip Rates

    NASA Astrophysics Data System (ADS)

    Hirose, T.; Mizoguchi, K.

    2008-12-01

    Determination of the energy partitioning during an earthquake is key to understanding the physics of earthquakes (e.g., Kanamori and Rivera, 2006). Observations made on natural faults that have experienced earthquakes suggest that part of the energy dissipates into a volume of rock surrounding the fault though grain crushing processes, forming fault gouge (e.g., Wilson et al., 2005). Thus we performed high-velocity wear experiments using a rotary-shear apparatus, in order to estimate the partitioning of the frictional work into heat and surface energy during frictional sliding at nearly coseismic slip rates. In particular, we attempted to test whether the ratio of the energy partitioning varies as a function of slip rate. The ratio of dissipated energy as heat to the total frictional work was estimated from the difference between measured temperature around the sliding surfaces and calculated temperature by 2D-FEM on the assumption that all frictional work converts into heat. The surface energy was estimated based on the particle size distribution of the wear materials, which was determined by FE-SEM image analysis. The particles size ranged between 0.03 and 10 μm in average diameter. In the experiments, hollow cylindrical specimens of gabbro were slid at slip rates of 0.004 to 0.3 m/s and normal stresses of 0.2 to 5.6 MPa under unconfined and dry conditions. Rock powder (gouge) was continuously produced by abrasive wear of initially bare fault surfaces during sliding. Because the sliding surfaces were not confined in the experiments, the gouge was extruded from the fault surfaces, resulting in shortening of axial length of specimen. In this study, we defined the dimensionless wear rate, given by that an axial shortening rate of the specimen was divided by slip rate. Then, we examined how the wear rate and temperature changed as a function of the rate of frictional work per a unit fault area, Ef, determined by shear stress multiplied by slip rate. Hereafter, Q and

  5. On Performability Theory and the Inverse Sliding Problem

    DTIC Science & Technology

    1994-03-01

    motion of a homogeneous circular ring or disk sliding on a plane under the action of Coulomb friction in [11]. They make some interesting observations...Algorithmic Foundations of Robotics (WAFR) 1994 Preprints, San Francisco, California. [4] S. Goyal, A. Ruina , and J. Papadopoulos. Planar Sliding With Dry... Ruina , and J. Papadopoulos. Planar Sliding With Dry Friction 2: Dynamics of Motion. Cornell University Department of Computer Science Tech Report, TR

  6. Second order sliding mode control for a quadrotor UAV.

    PubMed

    Zheng, En-Hui; Xiong, Jing-Jing; Luo, Ji-Liang

    2014-07-01

    A method based on second order sliding mode control (2-SMC) is proposed to design controllers for a small quadrotor UAV. For the switching sliding manifold design, the selection of the coefficients of the switching sliding manifold is in general a sophisticated issue because the coefficients are nonlinear. In this work, in order to perform the position and attitude tracking control of the quadrotor perfectly, the dynamical model of the quadrotor is divided into two subsystems, i.e., a fully actuated subsystem and an underactuated subsystem. For the former, a sliding manifold is defined by combining the position and velocity tracking errors of one state variable, i.e., the sliding manifold has two coefficients. For the latter, a sliding manifold is constructed via a linear combination of position and velocity tracking errors of two state variables, i.e., the sliding manifold has four coefficients. In order to further obtain the nonlinear coefficients of the sliding manifold, Hurwitz stability analysis is used to the solving process. In addition, the flight controllers are derived by using Lyapunov theory, which guarantees that all system state trajectories reach and stay on the sliding surfaces. Extensive simulation results are given to illustrate the effectiveness of the proposed control method.

  7. Slide less pathology”: Fairy tale or reality?

    PubMed Central

    Indu, M; Rathy, R; Binu, MP

    2016-01-01

    Pathology practice is significantly advanced in various frontiers. Therefore, “slide less digital” pathology will not be a mere imagination in near future. Digitalization of histopathological slides (whole slide imaging [WSI]) is possible with the help of whole slide scanner. The WSI has a positive impact not only in routine practice but also in research field, medical education and bioindustry. Even if digital pathology has definitive advantages, its widespread use is not yet possible. As it is an upcoming technology in our field, this article is aimed to discussessential aspects of WSI. PMID:27601824

  8. Extended Survival of Several Microorganisms and Relevant Amino Acid Biomarkers under Simulated Martian Surface Conditions as a Function of Burial Depth

    SciTech Connect

    Johnson, Adam; Pratt, L.M.; Vishnivetskaya, Tatiana A; Pfiffner, S. M.; Bryan, R. A.; Dadachova, E.; Whyte, L G; Radtke, K.; Chan, E.; Tronick, S.; Borgonie, G.; Mancinelli, R.; Rothschild, L.; Rogoff, D.; Horikawa, D. D.; Onstott, T. C.

    2011-01-01

    Recent orbital and landed missions have provided substantial evidence for ancient liquid water on the martian surface as well as evidence of more recent sedimentary deposits formed by water and/or ice. These observations raise serious questions regarding an independent origin and evolution of life on Mars. Future missions seek to identify signs of extinct martian biota in the form of biomarkers or morphological characteristics, but the inherent danger of spacecraft-borne terrestrial life makes the possibility of forward contamination a serious threat not only to the life detection experiments, but also to any extant martian ecosystem. A variety of cold and desiccation-tolerant organisms were exposed to 40 days of simulated martian surface conditions while embedded within several centimeters of regolith simulant in order to ascertain the plausibility of such organisms survival as a function of environmental parameters and burial depth. Relevant amino acid biomarkers associated with terrestrial life were also analyzed in order to understand the feasibility of detecting chemical evidence for previous biological activity. Results indicate that stresses due to desiccation and oxidation were the primary deterrent to organism survival, and that the effects of UV-associated damage, diurnal temperature variations, and reactive atmospheric species were minimal. Organisms with resistance to desiccation and radiation environments showed increased levels of survival after the experiment compared to organisms characterized as psychrotolerant. Amino acid analysis indicated the presence of an oxidation mechanism that migrated downward through the samples during the course of the experiment and likely represents the formation of various oxidizing species at mineral surfaces as water vapor diffused through the regolith. Current sterilization protocols may specifically select for organisms best adapted to survival at the martian surface, namely species that show tolerance to radical

  9. Physiological and productive responses of multiparous lactating Holstein cows exposed to short-term cooling during severe summer conditions in an arid region of Mexico

    NASA Astrophysics Data System (ADS)

    Avendaño-Reyes, L.; Hernández-Rivera, J. A.; Álvarez-Valenzuela, F. D.; Macías-Cruz, U.; Díaz-Molina, R.; Correa-Calderón, A.; Robinson, P. H.; Fadel, J. G.

    2012-11-01

    Heat stress generates a significant economic impact for the dairy industry in arid and semi-arid regions of the world, so that heat abatement is an important issue for dairy producers. The objective of this study was to evaluate effects of two short-term cooling periods on physiological and productive status of lactating Holstein cows during hot ambient temperatures. Thirty-nine multiparous cows were blocked by milk yield and assigned to one of three treatments including: control group (C), cows cooled before milking time (0500 and 1700 h daily, 1 h cooling); AM group, cows cooled at 1000 h and before milking (2 h cooling); and AM + PM group, cows cooled at 1100, 1500 and 2200 h, as well as before milking (4 h cooling). The cooling system was placed in the holding pen which the cows were moved through for cooling. Respiratory rate, and temperatures of thurl and right flank, were lower ( P < 0.05) in cows from the AM + PM group than AM and C cows during the morning and afternoon. However, udder temperature was higher in the AM + PM group compared to AM and C groups during the afternoon, although lower than the AM group during the morning. Rectal temperature was similar in all groups. Thyroxin concentrations tended ( P < 0.10) to be lower in AM + PM relative to the AM and C groups. The AM + PM group had higher ( P < 0.05) milk production than C (18.70 vs. 17.43 kg, respectively), and AM + PM cows had a trend ( P < 0.10) to increased milk energy output vs. the C and AM groups (13.75 vs. 13.18 and 13.15 Mcal, respectively). Protein and fat in milk, body condition score, glucose, cholesterol, triglycerides and triiodothyronine were similar among the groups. Four hours of cooling with spray and fans during severe summer temperatures only modestly improved milk yield of lactating Holstein cows.

  10. Reciprocating sliding wear of in-situ reinforced silicon nitride

    SciTech Connect

    Yust, C.S.

    1995-10-01

    The reciprocating sliding wear response of two in-situ reinforced-silicon nitride compositions provided by AlliedSignal have been evaluated. The materials were prepared by AlliedSignal-Ceramic Components Division and were tested at conditions of interest to the Bendix Engine Controls Division (South Bend, IN) and AlliedSignal Research and Technology (Des Plaines, IL). The materials are being considered for a variety of new applications, and the current tests provide critical friction and wear values under anticipated operating conditions. Both pin and disk specimens of GS-44 and GN-10 in-situ reinforced silicon nitride of specified dimensions for wear testing were provided by the AlliedSignal participants. An initial series of tests examined the unlubricated behavior of these materials at elevated temperature (up to 900 C) in an inert atmosphere. The results revealed excessive levels of both friction and wear in the unlubricated condition. The test conditions were modified to include the use of jet fuel as a lubricant because of an intended application in that medium. The introduction of the lubricant resulted in very limited wear of both the pin and disk specimens.

  11. Hydrogeology characterization of roto-translational slides in flysch rock masses

    NASA Astrophysics Data System (ADS)

    Ronchetti, F.; Borgatti, L.; Cervi, F.; Corsini, A.; Piccinini, L.; Vincenzi, V.; Truffelli, G.

    2009-04-01

    The hydrogeological characteristics of roto-traslational slides in flysch are complex, due to the inherent anisotropy and heterogeneity of such rock masses. The paper deals with the hydrogeological characterization of a reactivated roto-translational slide affecting Cretaceous flysch, located in the Northern Apennines of Italy. In situ permeability and pumping test, continuous monitoring of groundwater levels, hydrochemical and isotope analyses, and finally uranine tracers were the adopted prospecting methods. The landslide sector classified as rock slide extends for about 0.5 km2 and is characterized by a marked active sliding surface at 40 m depth. Borehole cores showed an upper 10-20 m landslide layer made of clayey debris, and a lower 20 m landslide layer made of highly fractured sandstone-rich flysch. Below sliding surface the flysch is much less fractured and it is overlying a clayey mélange. The hydraulic conductivity of both layers of the rock slide body was estimated with more than ten borehole permeability tests and by 5 slug-tests in open-pipe piezometers. Results highlighted a variability of permeability at different depths and locations, between 10-6 to 10-8 m/s, linked to fracturing of rock masses and to clay fraction. Groundwater levels were monitored for more than 3 years by means of transducers in 5 standpipe piezometers, fissured above or below the sliding surface. Results showed that two overlaying aquifers exist at the slope scale: an unconfined one, in the fractured flysch of the rock slide; a confined one, in the undisturbed flysch below sliding surface. Pore pressure in the unconfined aquifer is controlled by rainfall, with fluctuation of several meters occurring hours or days from onset of precipitation. On the contrary, pore pressure in the confined aquifer shows little response to precipitation events, has fluctuations of few meters related to seasonal trends, and maintains pressure head higher than that in the unconfined one. This makes

  12. Effects of Different Ligature Materials on Friction in Sliding Mechanics

    PubMed Central

    Khamatkar, Aparna; Sonawane, Sushma; Narkhade, Sameer; Gadhiya, Nitin; Bagade, Abhijit; Soni, Vivek; Betigiri, Asha

    2015-01-01

    Background: During orthodontic tooth movement friction occurs at the bracket wire interface. Out of the total force applied to the tooth movement, some of it is dissipated as friction, and the remainder is transferred to the supporting structures of the tooth to mediate tooth movement. However many factors affect friction, and method of arch wire ligation being an important contributing factor. Hence, this study was carried out to evaluate the effects of different ligature materials on friction in sliding mechanics and to compare the effect of environment (dry and wet) on friction produced in sliding mechanics. Materials and Methods: The evaluation of friction between the bracket and the archwire consisted of a simulated half arch fixed appliance with archwire ligated in a vertical position. Four 0.022” maxillary stainless steel premolar brackets having a - 0° torque and 0° angulation were aligned with a 0.019” × 0.025” stainless steel arch wire onto a rigid Plexiglass sheet. The movable test bracket was fitted with a 10 mm long, 0.045” thick stainless steel power arm on the bonding surface. Testing was performed on a Hounsfield material testing machine. A total of 100 g weight was suspended from the power arm and the load needed to move the bracket over the distance of not <4 mm across the central span was recorded separately. Fifteen representative readings were taken with one reading per test sample. Results: The results showed that the mean frictional force of different groups in dry and wet state was statistically significantly different. The mean frictional force in a dry state was statistically significantly higher than wet state in elastomeric group. Conclusion: The type of ligation material and environment significantly affected the degree of friction generated during sliding mechanics. Teflon coated stainless steel ligatures produced the least friction among the materials tested in both dry and wet conditions and there was no significant effect

  13. Screening and dotting virtual slides: A new challenge for cytotechnologists.

    PubMed

    Khalbuss, Walid E; Cuda, Jackie; Cucoranu, Ioan C

    2013-01-01

    Digital images are increasingly being used in cytopathology. Whole-slide imaging (WSI) is a digital imaging modality that uses computerized technology to scan and convert entire cytology glass slides into digital images that can be viewed on a digital display using the image viewer software. Digital image acquisition of cytology glass slides has improved significantly over the years due to the use of liquid-based preparations and advances in WSI scanning technology such as automatic multipoint pre-scan focus technology or z-stack scanning technology. Screening cytotechnologists are responsible for every cell that is present on an imaged slide. One of the challenges users have to overcome is to establish a technique to review systematically the entire imaged slide and to dot selected abnormal or significant findings. The scope of this article is to review the current user interface technology available for virtual slide navigation when screening digital slides in cytology. WSI scanner vendors provide tools, built into the image viewer software that allow for a more systematic navigation of the virtual slides, such as auto-panning, keyboard-controlled slide navigation and track map. Annotation tools can improve communication between the screener and the final reviewer or can be used for education. The tracking functionality allows recording of the WSI navigation process and provides a mechanism for confirmation of slide coverage by the screening cytotechnologist as well as a useful tool for quality assurance. As the WSI technology matures, additional features and tools to support navigation of a cytology virtual slide are anticipated.

  14. Catastrophic sliding bifurcations and onset of oscillations in a superconducting resonator.

    PubMed

    Jeffrey, M R; Champneys, A R; di Bernardo, M; Shaw, S W

    2010-01-01

    This paper presents a general analysis and a concrete example of the catastrophic case of a discontinuity-induced bifurcation in so-called Filippov nonsmooth dynamical systems. Such systems are characterized by discontinuous jumps in the right-hand sides of differential equations across a phase space boundary and are often used as physical models of stick-slip motion and relay control. Sliding bifurcations of periodic orbits have recently been shown to underlie the onset of complex dynamics including chaos. In contrast to previously analyzed cases, in this work a periodic orbit is assumed to graze the boundary of a repelling sliding region, resulting in its abrupt destruction without any precursive change in its stability or period. Necessary conditions for the occurrence of such catastrophic grazing-sliding bifurcations are derived. The analysis is illustrated in a piecewise-smooth model of a stripline resonator, where it can account for the abrupt onset of self-modulating current fluctuations. The resonator device is based around a ring of NbN containing a microbridge bottleneck, whose switching between normal and super conducting states can be modeled as discontinuous, and whose fast temperature versus slow current fluctuations are modeled by a slow-fast timescale separation in the dynamics. By approximating the slow component as Filippov sliding, explicit conditions are derived for catastrophic grazing-sliding bifurcations, which can be traced out as parameters vary. The results are shown to agree well with simulations of the slow-fast model and to offer a simple explanation of one of the key features of this experimental device.

  15. Sliding-Mode Control Applied for Robust Control of a Highly Unstable Aircraft

    NASA Technical Reports Server (NTRS)

    Vetter, Travis Kenneth

    2002-01-01

    An investigation into the application of an observer based sliding mode controller for robust control of a highly unstable aircraft and methods of compensating for actuator dynamics is performed. After a brief overview of some reconfigurable controllers, sliding mode control (SMC) is selected because of its invariance properties and lack of need for parameter identification. SMC is reviewed and issues with parasitic dynamics, which cause system instability, are addressed. Utilizing sliding manifold boundary layers, the nonlinear control is converted to a linear control and sliding manifold design is performed in the frequency domain. An additional feedback form of model reference hedging is employed which is similar to a prefilter and has large benefits to system performance. The effects of inclusion of actuator dynamics into the designed plant is heavily investigated. Multiple Simulink models of the full longitudinal dynamics and wing deflection modes of the forward swept aero elastic vehicle (FSAV) are constructed. Additionally a linear state space models to analyze effects from various system parameters. The FSAV has a pole at +7 rad/sec and is non-minimum phase. The use of 'model actuators' in the feedback path, and varying there design, is heavily investigated for the resulting effects on plant robustness and tolerance to actuator failure. The use of redundant actuators is also explored and improved robustness is shown. All models are simulated with severe failure and excellent tracking, and task dependent handling qualities, and low pilot induced oscillation tendency is shown.

  16. An implicit sliding-motion preserving regularisation via bilateral filtering for deformable image registration.

    PubMed

    Papież, Bartłomiej W; Heinrich, Mattias P; Fehrenbach, Jérome; Risser, Laurent; Schnabel, Julia A

    2014-12-01

    Several biomedical applications require accurate image registration that can cope effectively with complex organ deformations. This paper addresses this problem by introducing a generic deformable registration algorithm with a new regularization scheme, which is performed through bilateral filtering of the deformation field. The proposed approach is primarily designed to handle smooth deformations both between and within body structures, and also more challenging deformation discontinuities exhibited by sliding organs. The conventional Gaussian smoothing of deformation fields is replaced by a bilateral filtering procedure, which compromises between the spatial smoothness and local intensity similarity kernels, and is further supported by a deformation field similarity kernel. Moreover, the presented framework does not require any explicit prior knowledge about the organ motion properties (e.g. segmentation) and therefore forms a fully automated registration technique. Validation was performed using synthetic phantom data and publicly available clinical 4D CT lung data sets. In both cases, the quantitative analysis shows improved accuracy when compared to conventional Gaussian smoothing. In addition, we provide experimental evidence that masking the lungs in order to avoid the problem of sliding motion during registration performs similarly in terms of the target registration error when compared to the proposed approach, however it requires accurate lung segmentation. Finally, quantification of the level and location of detected sliding motion yields visually plausible results by demonstrating noticeable sliding at the pleural cavity boundaries.

  17. Submarine faults and slides on the continental shelf, northern Gulf of Alaska

    USGS Publications Warehouse

    Carlson, Paul R.; Molnia, Bruce F.

    1977-01-01

    Submarine faults and slides or slumps of Quaternary age are potential environmental hazards on the outer continental shelf (OCS) of the northern Gulf of Alaska. Most faults that approach or reach the seafloor cut strata that may be equivalent in age to the upper Yakataga Formation (Pliocene‐Pleistocene). Along several faults, the seafloor is vertically offset from 5 to 20 m. A few faults appear to cut Holocene sediments, but none of these shows displacement at the seafloor. Submarine slides or slumps have been found in two places in the OCS region: (1) seaward of the Malaspina Glacier and Icy Bay, an area of 1200 km2 with a slope of less than 0.5°, and (2) across the entire span of the Copper river prodelta, an area of 1730 km2, having a slope of about 0.5°. Seismic profiles across these areas show disrupted reflectors and irregular topography commonly associated with submarine slides or slumps. Potential slide or slump areas have been delineated in areas of thick sediment accumulation and relatively steep slopes. These areas include (1) Kayak Trough, (2) parts of Hinchinbrook Entrance and Sea Valley, (3) parts of the outer shelf and upper slope between Kayak Island and Yakutat Bay, and (4) Bering Trough.

  18. Sliding Mode Control of Steerable Needles

    PubMed Central

    Rucker, D. Caleb; Das, Jadav; Gilbert, Hunter B.; Swaney, Philip J.; Miga, Michael I.; Sarkar, Nilanjan; Webster, Robert J.

    2014-01-01

    Steerable needles can potentially increase the accuracy of needle-based diagnosis and therapy delivery, provided they can be adequately controlled based on medical image information. We propose a novel sliding mode control law that can be used to deliver the tip of a flexible asymmetric-tipped needle to a desired point, or to track a desired trajectory within tissue. The proposed control strategy requires no a priori knowledge of model parameters, has bounded input speeds, and requires little computational resources. We show that if the standard nonholonomic model for tip-steered needles holds, then the control law will converge to desired targets in a reachable workspace, within a tolerance that can be defined by the control parameters. Experimental results validate the control law for target points and trajectory following in phantom tissue and ex vivo liver. Experiments with targets that move during insertion illustrate robustness to disturbances caused by tissue deformation. PMID:25400527

  19. Sliding Mode Control of Steerable Needles.

    PubMed

    Rucker, D Caleb; Das, Jadav; Gilbert, Hunter B; Swaney, Philip J; Miga, Michael I; Sarkar, Nilanjan; Webster, Robert J

    2013-10-01

    Steerable needles can potentially increase the accuracy of needle-based diagnosis and therapy delivery, provided they can be adequately controlled based on medical image information. We propose a novel sliding mode control law that can be used to deliver the tip of a flexible asymmetric-tipped needle to a desired point, or to track a desired trajectory within tissue. The proposed control strategy requires no a priori knowledge of model parameters, has bounded input speeds, and requires little computational resources. We show that if the standard nonholonomic model for tip-steered needles holds, then the control law will converge to desired targets in a reachable workspace, within a tolerance that can be defined by the control parameters. Experimental results validate the control law for target points and trajectory following in phantom tissue and ex vivo liver. Experiments with targets that move during insertion illustrate robustness to disturbances caused by tissue deformation.

  20. Investigations of the air flow velocity field structure above the wavy surface under severe wind conditions by particle image velosimetry technique.

    NASA Astrophysics Data System (ADS)

    Troitskaya, Yuliya; Kandaurov, Alexander; Sergeev, Daniil; Ermakova, Olga

    2013-04-01

    both method were in a good agreement. The application of PIV method enabled us measuring wind velocity profiles much closer to water surface than in the case of contact method. As a result there exists the logarithmic parts in velocity profiles, which yield turbulent momentum flux from the slope and also the equivalent 10-m wind speed and the surface drag coefficient. It was shown that similarly to [2] the surface drag coefficient tends to saturate at wind velocities exceeding 25 m/s. The decrease of the water surface drag coefficient with wind velocity increase was not observed. This work was supported by RFBR (project 11-05-12047-ofi-m, 13-05-00865-a, 12-05-33070 mol-a-ved, 12-05-31435 mol-a, 12-05-01064-a). References 1. Canny, J. A. Computational approach to edge detection/ J.A. Canny// IEEE Trans. Pattern Analysis and Machine Intelligence. - 1986. - V. 8(6). - P. 679-698.. 2. Troitskaya, Y. I., D. A. Sergeev, A. A. Kandaurov, G. A. Baidakov, M. A. Vdovin, and V. I. Kazakov Laboratory and theoretical modeling of air-sea momentum transfer under severe wind conditions J.Geophys. Res., 117, C00J21, doi:10.1029/2011JC007778.

  1. Physiological and productive responses of multiparous lactating Holstein cows exposed to short-term cooling during severe summer conditions in an arid region of Mexico.

    PubMed

    Avendaño-Reyes, L; Hernández-Rivera, J A; Alvarez-Valenzuela, F D; Macías-Cruz, U; Díaz-Molina, R; Correa-Calderón, A; Robinson, P H; Fadel, J G

    2012-11-01

    Heat stress generates a significant economic impact for the dairy industry in arid and semi-arid regions of the world, so that heat abatement is an important issue for dairy producers. The objective of this study was to evaluate effects of two short-term cooling periods on physiological and productive status of lactating Holstein cows during hot ambient temperatures. Thirty-nine multiparous cows were blocked by milk yield and assigned to one of three treatments including: control group (C), cows cooled before milking time (0500 and 1700 h daily, 1 h cooling); AM group, cows cooled at 1000 h and before milking (2 h cooling); and AM + PM group, cows cooled at 1100, 1500 and 2200 h, as well as before milking (4 h cooling). The cooling system was placed in the holding pen which the cows were moved through for cooling. Respiratory rate, and temperatures of thurl and right flank, were lower (P < 0.05) in cows from the AM + PM group than AM and C cows during the morning and afternoon. However, udder temperature was higher in the AM + PM group compared to AM and C groups during the afternoon, although lower than the AM group during the morning. Rectal temperature was similar in all groups. Thyroxin concentrations tended (P < 0.10) to be lower in AM + PM relative to the AM and C groups. The AM + PM group had higher (P < 0.05) milk production than C (18.70 vs. 17.43 kg, respectively), and AM + PM cows had a trend (P < 0.10) to increased milk energy output vs. the C and AM groups (13.75 vs. 13.18 and 13.15 Mcal, respectively). Protein and fat in milk, body condition score, glucose, cholesterol, triglycerides and triiodothyronine were similar among the groups. Four hours of cooling with spray and fans during severe summer temperatures only modestly improved milk yield of lactating Holstein cows.

  2. Segmentation of vessel structures in serial whole slide sections using region-based context features

    NASA Astrophysics Data System (ADS)

    Schwier, Michael; Hahn, Horst K.; Dahmen, Uta; Dirsch, Olaf

    2016-03-01

    We present a method for the automatic segmentation of vascular structures in stacks of serial sections. It was initially motivated within the Virtual Liver Network research project that aims at creating a multi-scale virtual model of the liver. For this the vascular systems of several murine livers under different conditions need to be analyzed. To get highly detailed datasets, stacks of serial sections of the whole organs are prepared. Due to the huge amount of image data an automatic approach for segmenting the vessels is required. After registering the slides with an established method we use a set of Random Forest classifiers to distinguish vessels from tissue. Instead of a pixel-wise approach we perform the classification on small regions. This allows us to use more meaningful features. Besides basic intensity and texture features we introduce the concept of context features, which allow the classifiers to also consider the neighborhood of a region. Classification is performed in two stages. In the second stage the previous classification result of a region and its neighbors is used to refine the decision for a particular region. The context features and two stage classification process make our method very successful. It can handle different stainings and also detect vessels in which residue like blood cells remained. The specificity reaches 95%-99% for pure tissue, depending on staining and zoom level. Only in the direct vicinity of vessels the specificity declines to 88%-96%. The sensitivity rates reach between 89% and 98%.

  3. Grain Boundary Sliding in Ultra-fine Grained 5083 Aluminium Alloy

    NASA Astrophysics Data System (ADS)

    Sung, Ming-Je

    Quantitative measurement and analysis of grain boundary sliding in Ultra-fine grained 5083 Aluminium by AFM was conducted at 623K. The grain size of as received cryomilled Ultra-fine Grained Aluminium was characterized by AFM and TEM, and the average was founded to be about 300nm. Ion beam polishing / etching technology was used to reveal grain boundaries for AFM characterization. The vertical offset of grain boundary sliding was measured by comparing pre-defoemation and post-deformation AFM images. By analyzing these measurements, the contribution of grain boundary sliding to the total strain was estimated as 22% - 52% at a strain rate of 10 -4 /sec -5x10-2/sec. It was demonstrated that the relatively low value of the contribution of grain boundary sliding to the total strain is most likely the result of testing under experimental condition that favor the dominance of region I ( low stress) of the sigmoidal behavior characterizing high strain rate superplasticity, which was previously reported.

  4. Sliding Mode Control of the X-33 with an Engine Failure

    NASA Technical Reports Server (NTRS)

    Shtessel, Yuri B.; Hall, Charles E.

    2000-01-01

    Ascent flight control of the X-3 is performed using two XRS-2200 linear aerospike engines. in addition to aerosurfaces. The baseline control algorithms are PID with gain scheduling. Flight control using an innovative method. Sliding Mode Control. is presented for nominal and engine failed modes of flight. An easy to implement, robust controller. requiring no reconfiguration or gain scheduling is demonstrated through high fidelity flight simulations. The proposed sliding mode controller utilizes a two-loop structure and provides robust. de-coupled tracking of both orientation angle command profiles and angular rate command profiles in the presence of engine failure, bounded external disturbances (wind gusts) and uncertain matrix of inertia. Sliding mode control causes the angular rate and orientation angle tracking error dynamics to be constrained to linear, de-coupled, homogeneous, and vector valued differential equations with desired eigenvalues. Conditions that restrict engine failures to robustness domain of the sliding mode controller are derived. Overall stability of a two-loop flight control system is assessed. Simulation results show that the designed controller provides robust, accurate, de-coupled tracking of the orientation angle command profiles in the presence of external disturbances and vehicle inertia uncertainties, as well as the single engine failed case. The designed robust controller will significantly reduce the time and cost associated with flying new trajectory profiles or orbits, with new payloads, and with modified vehicles

  5. Investigation of transient temperature's influence on damage of high-speed sliding electrical contact rail surface

    NASA Astrophysics Data System (ADS)

    Zhang, Yuyan; Sun, Shasha; Guo, Quanli; Yang, Degong; Sun, Dongtao

    2016-11-01

    In the high speed sliding electrical contact with large current, the temperature of contact area rises quickly under the coupling action of the friction heating, the Joule heating and electric arc heating. The rising temperature seriously affects the conductivity of the components and the yield strength of materials, as well affects the contact state and lead to damage, so as to shorten the service life of the contact elements. Therefore, there is vital significance to measure the temperature accurately and investigate the temperature effect on damage of rail surface. Aiming at the problem of components damage in high speed sliding electrical contact, the transient heat effect on the contact surface was explored and its influence and regularity on the sliding components damage was obtained. A kind of real-time temperature measurement method on rail surface of high speed sliding electrical contact is proposed. Under the condition of 2.5 kA current load, based on the principle of infrared radiation non-contact temperature sensor was used to measure the rail temperature. The dynamic distribution of temperature field was obtained through the simulation analysis, further, the connection between temperature changes and the rail surface damage morphology, the damage volume was analyzed and established. Finally, the method to reduce rail damage and improve the life of components by changing the temperature field was discussed.

  6. Incidence and risk factors for moderate-to-severe veno-occlusive disease of the liver after allogeneic stem cell transplantation using a reduced intensity conditioning regimen.

    PubMed

    Tsirigotis, P D; Resnick, I B; Avni, B; Grisariu, S; Stepensky, P; Or, R; Shapira, M Y

    2014-11-01

    The incidence and outcome of moderate-to-severe veno-occlusive (VOD) disease was analyzed in 271 consecutive patients with hematological malignancies who underwent allogeneic SCT (allo-SCT) using the same reduced intensity regimen (RIC). RIC consisted of fludarabine, BU and antithymocyte globulin (ATG). Twenty-four out of 271 patients (8.8%) developed VOD, which was severe in only 4 (1.4%) out of 24 cases. All four patients with severe VOD finally succumbed to their disease. In multivariate analysis, i.v. administration of BU was associated with significant reduced incidence of VOD as compared with per os administration. In conclusion, VOD remains a serious complication of allo-SCT using RIC regimens containing BU. Although the incidence of severe VOD is very low, the overall mortality rate in the group of patients with severe VOD remains extremely high and therefore novel treatment approaches are needed.

  7. AFRD WAREHOUSE, WEST SIDE DETAIL OF ALTERED SLIDING DOORS, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AFRD WAREHOUSE, WEST SIDE DETAIL OF ALTERED SLIDING DOORS, FACING EAST. WEATHER COVER OVER RAIL IS ORIGINAL. SHEET METAL SIDING HAS BEEN INSERTED BETWEEN TWO HALVES OF SLIDING DOORS. - Minidoka Relocation Center Warehouse, 111 South Fir Street, Shoshone, Lincoln County, ID

  8. Lecture Handouts of Projected Slides in a Medical Course.

    ERIC Educational Resources Information Center

    Amato, Dominick; Quirt, Ian

    1991-01-01

    In a third-year medical school hematology course, handouts reproducing all or most of the 35mm slides used during the lecture are given at the beginning of class. The slides are reproduced on the left, with room for note-taking on the right. Despite some disadvantages, the method is seen as helpful. (Author/MSE)

  9. A Transformational Approach to Slip-Slide Factoring

    ERIC Educational Resources Information Center

    Steckroth, Jeffrey

    2015-01-01

    In this "Delving Deeper" article, the author introduces the slip-slide method for solving Algebra 1 mathematics problems. This article compares the traditional method approach of trial and error to the slip-slide method of factoring. Tools that used to be taken for granted now make it possible to investigate relationships visually,…

  10. Analysis of tensioned membrane structures considering cable sliding.

    PubMed

    Song, Chang-yong

    2003-01-01

    In routine design of tensioned membrane structures, the membrane is generally modeled using space membrane elements and the cables by space cable elements, with no sliding allowed between the membrane and the cables. On the other hand, large deflections are expected and sliding between the membrane and the cables is inevitable. In the present paper, the general finite element code ABAQUS was employed to investigate the influence of cable sliding on membrane surface on the structural behavior. Three analysis models were devised to fulfill this purpose: (1) The membrane element shares nodes with the cable element; (2) The cable can slide on the membrane surface freely (without friction) and (3) The cable can slide on the membrane surface, but with friction between the cable and the membrane. The sliding problem is modeled using a surface-based contact algorithm. The results from three analysis models are compared, showing that cable sliding has only little influence on the structure shape and on the stress distributions in the membrane. The main influence of cable sliding may be its effect on the dynamic behavior of tensioned membrane structures.

  11. Qualification test unit slide stainer (Beckman P/N 673753)

    NASA Technical Reports Server (NTRS)

    Bernier, P. S.

    1972-01-01

    Specifications for a slide stainer unit for the Skylab program are presented. The qualification test slide stainer was designed to be a self-contained system capable of performing an eight-step Gram stain of microorganisms and a Wright's stain of blood smears.

  12. A Simple Measurement of the Sliding Friction Coefficient

    ERIC Educational Resources Information Center

    Gratton, Luigi M.; Defrancesco, Silvia

    2006-01-01

    We present a simple computer-aided experiment for investigating Coulomb's law of sliding friction in a classroom. It provides a way of testing the possible dependence of the friction coefficient on various parameters, such as types of materials, normal force, apparent area of contact and sliding velocity.

  13. Determining the Ecosystem Services Important for Urban Landscapes-Slides

    EPA Science Inventory

    This presentation consists of introductory slides on ecosystem services in urban landscapes and then a discussion of two case studies concerning the provision of water quality in urban landscapes. The introductory slides will explore the range of ecosystem services provided by u...

  14. 8. Photocopy of original USRS glass plate slide (from original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopy of original USRS glass plate slide (from original slide on file at National Archives, Rocky Mountain Region, Denver, Colorado) Photographer unknown, ca. 1908 The diversion weir of the Okanogan National Irrigation Project - Salmon Creek Diversion Dam, Salmon Creek, Okanogan, Okanogan County, WA

  15. 45 CFR 98.42 - Sliding fee scales.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider Requirements § 98.42 Sliding fee scales... provides for cost sharing by families that receive CCDF child care services. (b) A sliding fee...

  16. 45 CFR 98.42 - Sliding fee scales.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider Requirements § 98.42 Sliding fee scales... provides for cost sharing by families that receive CCDF child care services. (b) A sliding fee...

  17. 45 CFR 98.42 - Sliding fee scales.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider Requirements § 98.42 Sliding fee scales... provides for cost sharing by families that receive CCDF child care services. (b) A sliding fee...

  18. 45 CFR 98.42 - Sliding fee scales.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Welfare Department of Health and Human Services GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider Requirements § 98.42 Sliding fee scales... provides for cost sharing by families that receive CCDF child care services. (b) A sliding fee...

  19. 45 CFR 98.42 - Sliding fee scales.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Lead Agency and Provider Requirements § 98.42 Sliding fee scales... provides for cost sharing by families that receive CCDF child care services. (b) A sliding fee...

  20. Computer Slide Shows: A Trap for Bad Teaching

    ERIC Educational Resources Information Center

    Klemm, W. R.

    2007-01-01

    Slide shows presented with software such as PowerPoint or WordPerfect Presentations can trap instructors into bad teaching practices. Research on memory suggests that slide-show instruction can actually be less effective than traditional lecturing when the teacher uses a blackboard or overhead projector. The author proposes a model of classroom…

  1. Robust spatiotemporal matching of electronic slides to presentation videos.

    PubMed

    Fan, Quanfu; Barnard, Kobus; Amir, Arnon; Efrat, Alon

    2011-08-01

    We describe a robust and efficient method for automatically matching and time-aligning electronic slides to videos of corresponding presentations. Matching electronic slides to videos provides new methods for indexing, searching, and browsing videos in distance-learning applications. However, robust automatic matching is challenging due to varied frame composition, slide distortion, camera movement, low-quality video capture, and arbitrary slides sequence. Our fully automatic approach combines image-based matching of slide to video frames with a temporal model for slide changes and camera events. To address these challenges, we begin by extracting scale-invariant feature-transformation (SIFT) keypoints from both slides and video frames, and matching them subject to a consistent projective transformation (homography) by using random sample consensus (RANSAC). We use the initial set of matches to construct a background model and a binary classifier for separating video frames showing slides from those without. We then introduce a new matching scheme for exploiting less distinctive SIFT keypoints that enables us to tackle more difficult images. Finally, we improve upon the matching based on visual information by using estimated matching probabilities as part of a hidden Markov model (HMM) that integrates temporal information and detected camera operations. Detailed quantitative experiments characterize each part of our approach and demonstrate an average accuracy of over 95% in 13 presentation videos.

  2. Computer Control of a Random Access Slide Projector.

    ERIC Educational Resources Information Center

    Barker, Philip G.

    1982-01-01

    A description of a simple interface to enable the interconnection of a random access slide projector and a microcomputer is provided, as well as summaries of the role of slide images as a means of implementing graphic communication and the new activity in graphics as an area of information processing. The microcomputer interface is then detailed,…

  3. Design Your Organization's Own Slide-Tape Show

    ERIC Educational Resources Information Center

    Tilden, Scott W.

    1975-01-01

    Slide-tape shows offer a relatively inexpensive, easy-to-assemble means of informing a wide variety of groups interested in education. This article outlines a seven-step procedure to produce a coherent, professional-looking slide-tape presentation. (DS)

  4. The Easy Way to Create Computer Slide Shows.

    ERIC Educational Resources Information Center

    Anderson, Mary Alice

    1995-01-01

    Discusses techniques for creating computer slide shows. Topics include memory; format; color use; HyperCard and CD-ROM; font styles and sizes; graphs and graphics; the slide show option; special effects; and tips for effective presentation. (Author/AEF)

  5. Optimizing Student Learning: Examining the Use of Presentation Slides

    ERIC Educational Resources Information Center

    Strauss, Judy; Corrigan, Hope; Hofacker, Charles F.

    2011-01-01

    Sensory overload and split attention result in reduced learning when instructors read slides with bullet points and complex graphs during a lecture. Conversely, slides containing relevant visual elements, when accompanied by instructor narration, use both the visual and verbal channels of a student's working memory, thus improving the chances of…

  6. A model for predicting pathologist's velocity profiles when navigating virtual slides.

    PubMed

    Gómez, Francisco; Romero, Eduardo

    2010-02-01

    Navigation through large microscopic images is a potential benefit for histology or pathology teaching, for improving the quality of diagnosis in pathology, or for communicating pathologists in some telemedicine applications. However, the size of this kind of images is prohibitive for navigation with conventional techniques. This article presents a soft computing model, which permits to anticipate the pathologist trajectories in diagnosis tasks when exploring virtual slides. The Bayesian strategy combines an offline model of a baseline pathologist knowledge (the prior) and a prediction online module (the likelihood) that captures a particular pathologist navigation pattern. While optimal parameters for the biologically inspired offline model are calculated using an Expectation-Maximization strategy, prediction is carried out by a particle filter. Parameters are estimated from several series of actual navigations performed by several pathologists in different virtual slides. The present approach is compared with other conventional prediction methods and decreases the calculated MSE in about a 50% for the entire group of pathologists.

  7. Effects of induced vibration modes on droplet sliding phenomena

    NASA Astrophysics Data System (ADS)

    Mejia, Jose Eduardo; Alvarado, Jorge; Yao, Chun-Wei; Dropwise Condensation Collaboration; Engineered Surfaces Collaboration

    2016-11-01

    An analytical and experimental investigation has been undertaken to understand the effects of induced vibration modes on droplet sliding phenomena. A mathematical model has been postulated which is capable of estimating accurately droplet sliding angles when using hydrophobic and hydrophilic surfaces. The model, which takes into account equilibrium contact angle, contact angle hysteresis, and droplet volume, has been validated using experimental data. The model has been modified to be able to estimate droplet sliding angle when different modes of vibrations are imposed on the surfaces. Experimental results to date reveal that when resonance modes of vibrations are imposed, the droplet sliding angles decrease considerably. The results also indicate that the modified model can be used effectively to relate imposed resonance frequencies to the critical sliding angle of droplets. LSAMP sponsored NSF Fellowship.

  8. Teaching Veterinary Histopathology: A Comparison of Microscopy and Digital Slides.

    PubMed

    Brown, Peter J; Fews, Debra; Bell, Nick J

    2016-01-01

    Virtual microscopy using digitized slides has become more widespread in teaching in recent years. There have been no direct comparisons of the use of virtual microscopy and the use of microscopes and glass slides. Third-year veterinary students from two different schools completed a simple objective test, covering aspects of histology and histopathology, before and after a practical class covering relevant material presented as either glass slides viewed with a microscope or as digital slides. There was an overall improvement in performance by students at both veterinary schools using both practical formats. Neither format was consistently better than the other, and neither school consistently outperformed the other. In a comparison of student appraisal of use of digital slides and microscopes, the digital technology was identified as having many advantages.

  9. Static and dynamic friction in sliding colloidal monolayers

    PubMed Central

    Vanossi, Andrea; Manini, Nicola; Tosatti, Erio

    2012-01-01

    In a pioneer experiment, Bohlein et al. realized the controlled sliding of two-dimensional colloidal crystals over laser-generated periodic or quasi-periodic potentials. Here we present realistic simulations and arguments that besides reproducing the main experimentally observed features give a first theoretical demonstration of the potential impact of colloid sliding in nanotribology. The free motion of solitons and antisolitons in the sliding of hard incommensurate crystals is contrasted with the soliton–antisoliton pair nucleation at the large static friction threshold Fs when the two lattices are commensurate and pinned. The frictional work directly extracted from particles’ velocities can be analyzed as a function of classic tribological parameters, including speed, spacing, and amplitude of the periodic potential (representing, respectively, the mismatch of the sliding interface and the corrugation, or “load”). These and other features suggestive of further experiments and insights promote colloid sliding to a unique friction study instrument. PMID:23019582

  10. Extended observer based on adaptive second order sliding mode control for a fixed wing UAV.

    PubMed

    Castañeda, Herman; Salas-Peña, Oscar S; León-Morales, Jesús de

    2017-01-01

    This paper addresses the design of attitude and airspeed controllers for a fixed wing unmanned aerial vehicle. An adaptive second order sliding mode control is proposed for improving performance under different operating conditions and is robust in presence of external disturbances. Moreover, this control does not require the knowledge of disturbance bounds and avoids overestimation of the control gains. Furthermore, in order to implement this controller, an extended observer is designed to estimate unmeasurable states as well as external disturbances. Additionally, sufficient conditions are given to guarantee the closed-loop stability of the observer based control. Finally, using a full 6 degree of freedom model, simulation results are obtained where the performance of the proposed method is compared against active disturbance rejection based on sliding mode control.

  11. DPS Discovery Slide Sets for the Introductory Astronomy Instructor

    NASA Astrophysics Data System (ADS)

    Meinke, Bonnie K.; Jackson, Brian; Buxner, Sanlyn; Horst, Sarah; Brain, David; Schneider, Nicholas M.

    2016-10-01

    The DPS actively supports the E/PO needs of the society's membership, including those at the front of the college classroom. The DPS Discovery Slide Sets are an opportunity for instructors to put the latest planetary science into their lectures and for scientists to get their exciting results to college students.In an effort to keep the astronomy classroom apprised of the fast moving field of planetary science, the Division for Planetary Sciences (DPS) has developed "DPS Discoveries", which are 3-slide presentations that can be incorporated into college lectures. The slide sets are targeted at the Introductory Astronomy undergraduate level. Each slide set consists of three slides which cover a description of the discovery, a discussion of the underlying science, and a presentation of the big picture implications of the discovery, with a fourth slide that includes links to associated press releases, images, and primary sources. Topics span all subdisciplines of planetary science, and 26 sets are available in Farsi and Spanish. We intend for these slide sets to help Astronomy 101 instructors include new developments (not yet in their textbooks) into the broader context of the course. If you need supplemental material for your classroom, please checkout the archived collection: http://dps.aas.org/education/dpsdiscMore slide sets are now in development and will be available soon! In the meantime, we seek input, feedback, and help from the DPS membership to add fresh slide sets to the series and to connect the college classroom to YOUR science. It's easy to get involved - we'll provide a content template, tips and tricks for a great slide set, and pedagogy reviews. Talk to a coauthor to find out how you can disseminate your science or get involved in E/PO with your contributions.

  12. Evaluation of 2 whole-slide imaging applications in dermatopathology.

    PubMed

    Velez, Nicole; Jukic, Drazen; Ho, Jonhan

    2008-09-01

    Digitization of glass slides holds great promise for increasing workflow efficiency, but current applications have not gained widespread acceptance. Applications to date have not taken into consideration pathologists' workflow patterns, and as a result many find navigation cumbersome and interpretation more challenging when compared to glass slides. We observed 3 dermatopathologists evaluate a set of cases using 2 digital applications, one of which used a novel navigation method developed in-house. We then compared their approach to the digital slides with the gold standard traditional microscopy with glass slides. Common diagnoses were identified in 3 categories: inflammatory, nonmelanocytic, and melanocytic lesions. Forty-five cases were selected representing these diagnoses. Digital slides were captured on a commercially available scanner. Sign-out was performed with a commercial viewer as well as with the in-house application. Sessions were captured on video and reviewed. Time to examine each slide, time spent at each magnification, and diagnostic concordance were measured. Average time spent per slide was least with the microscope (23 seconds) as compared with the in-house (34 seconds) or the vendor application (38 seconds). This difference was most significant in the least complex cases. Pathologists reported difficulty interpreting mitotic figures, neutrophil lobules, and eosinophil granules by digital slides. These results suggest that current applications for viewing digital slides do not yet provide a more efficient means of evaluating dermatopathology cases and reinforce the need for improvement in both the capture process and the presentation of digital slides, with particular attention paid to the interface and navigation.

  13. Improving protein array performance: focus on washing and storage conditions.

    PubMed

    Nath, Nidhi; Hurst, Robin; Hook, Brad; Meisenheimer, Poncho; Zhao, Kate Q; Nassif, Nadine; Bulleit, Robert F; Storts, Douglas R

    2008-10-01

    For protein microarrays, maintaining protein stability during the slide processing steps of washing, drying, and storage is of major concern. Although several studies have focused on the stability of immobilized antibodies in antibody microarrays, studies on protein-protein interaction arrays and enzyme arrays are lacking. In this paper we used five bait-prey protein interaction pairs and three enzymes to optimize the washing, drying, and storage conditions for protein arrays. The protein arrays for the study were fabricated by combining HaloTag technology and cell-free protein expression. The HaloTag technology, in combination with cell-free expression, allowed rapid expression and immobilization of fusion proteins on hydrogel-coated glass slides directly from cell extracts without any prior purification. Experimental results indicate enzyme captured on glass slides undergoes significant loss of activity when washed and spin-dried using only phosphate buffer, as is typically done with antibody arrays. The impact of washing and spin-drying in phosphate buffer on protein-protein interaction arrays was minimal. However, addition of 5% glycerol to the wash buffer helps retain enzyme activity during washing and drying. We observed significant loss of enzyme activity when slides were stored dry at 4 degrees C, however immobilized enzymes remained active for 30 days when stored at -20 degrees C in 50% glycerol. We also found that cell-free extract containing HaloTag-fused enzymes could undergo multiple freeze/thaw cycles without any adverse impact on enzyme activity. The findings indicate that for large ongoing studies, proteins of interest expressed in cell-free extract can be stored at -70 degrees C and repeatedly used to print small batches of protein array slides to be used over a few weeks.

  14. Terrain analysis of the racetrack basin and the sliding rocks of Death Valley

    USGS Publications Warehouse

    Messina, P.; Stoffer, P.

    2000-01-01

    The Racetrack Playa's unusual surface features known as sliding rocks have been the subject of an ongoing debate and several mapping projects for half a century, although the causative mechanism remains unresolved. Clasts ranging in volume from large pebbles to medium boulders have, unwitnessed, maneuvered around the nearly flat dry lake over considerable distances. The controversy has persisted partly because eyewitness accounts of the phenomenon continue to be lacking, and the earlier mapping missions were limited in method and geographic range. In July 1996, we generated the first complete map of all observed sliding rock trails by submeter differential Global Positioning System (DGPS) mapping technology. The resulting map shows 162 sliding rocks and associated trails to an accuracy of approximately 30 cm. Although anemometer data are not available in the Racetrack wilderness, wind is clearly a catalyst for sliding rock activity; an inferred wind rose was constructed from DGPS trail segment data. When the entire trail network is examined in plan, some patterns emerge, although other (perhaps expected relations) remain elusive: terrain analysis of the surrounding topography demonstrates that the length and morphology of trails are more closely related to where rocks rested at the onset of motion than to any physical attribute of the rocks themselves. Follow-up surveys in May 1998, May 1999, August 1999, and November 1999 revealed little modification of the July, 1996 sliding rock configuration. Only four rocks were repositioned during the El Nino winter of 1997-1998, suggesting that activity may not be restricted to winter storms. (C) 2000 Elsevier Science B.V. All rights reserved.

  15. Sliding-cavity fluid contactors in low-gravity fluids, materials, and biotechnology research.

    PubMed

    Todd, Paul; Vellinger, John C; Sengupta, Shramik; Sportiello, Michael G; Greenberg, Alan R; Krantz, William B

    2002-10-01

    The well-known method of sliding-cavity fluid contactors used by Gosting for diffusion measurements and by Tiselius in electrophoresis has found considerable use in low-gravity research. To date, sliding-cavity contactors have been used in liquid diffusion experiments, interfacial transport experiments, biomolecular crystal growth, biphasic extraction, multistage extraction, microencapsulation, seed germination, invertebrate development, and thin-film casting. Sliding-cavity technology has several advantages for spaceflight: it is simple, it accommodates small samples, samples can be fully enclosed, phases can be combined, multiple samples can be processed at high sample density, real-time observations can be made, and mixed and diffused samples can be compared. An analysis of the transport phenomena that govern the sliding-cavity method is offered. During sliding of one liquid over another flow rates between 0.001 and 0.1m/sec are developed, giving Reynolds numbers in the range 0.1-100. Assuming no slip at liquid-solid boundaries shear rates are of the order 1sec(-1). The measured consequence is the transfer of 2-5% of the content of a cavity to the opposite cavity. In the absence of gravity, buoyancy-driven transport is assumed absent. Transport processes are limited to (1) molecular diffusion, in which reactants diffuse toward one another at rates that depend on their diffusion coefficient and concentration gradient (Fick's second law), (2) solutocapillary (Marangoni) flow driven by surface-tension gradients, (3) capillary flow (drop spreading) at liquid-solid three-phase lines leading to immiscible phase demixing, and (4) vapor-phase diffusive mass transfer in evaporative processes. Quantitative treatment of these phenomena has been accomplished over the past few years in low-gravity research in space and on aircraft.

  16. Validation of whole slide imaging for frozen section diagnosis in surgical pathology

    PubMed Central

    Bauer, Thomas W.; Slaw, Renee J.; McKenney, Jesse K.; Patil, Deepa T.

    2015-01-01

    Background: Whole slide imaging (WSI) using high-resolution scanners is gaining acceptance as a platform for consultation as well as for frozen section (FS) evaluation in surgical pathology. We report results of an intra-observer concordance study comparing evaluation of WSI of scanned FS microscope slides with the original interpretation of the same microscope slides after an average lag time of approximately 1-year. Methods: A total of 70 FS cases (148 microscope slides) originally interpreted by 2 pathologists were scanned at ×20 using Aperio CS2 scanner (Leica Biosystems, San Diego, CA, USA). Reports were redacted such that the study pathologists reviewed images using eSlide Manager Healthcare Network application (Leica Biosystems) accompanied by the same clinical information available at the time of original FS evaluation. Discrepancies between the original FS diagnosis and WSI diagnosis were categorized as major (impacted patient care) or minor (no impact on patient care). Results: Lymph nodes, margins for head and neck cancer resections, and arthroplasty specimens to exclude infection, were the most common FS specimens. The average wash-out interval was 380 days (range: 303–466 days). There was one major discrepancy (1.4% of 70 cases) where the original FS was interpreted as severe squamous dysplasia, and the WSI FS diagnosis was mild dysplasia. There were two minor discrepancies; one where the original FS was called focal moderate squamous dysplasia and WSI FS diagnosis was negative for dysplasia. The second case was an endometrial adenocarcinoma that was originally interpreted as Federation of Gynecology and Obstetrics (FIGO) Grade I, while the WSI FS diagnosis was FIGO Grade II. Conclusions: These findings validate and support the use of WSI to provide interpretation of FS in our network of affiliated hospitals and ambulatory surgery centers. PMID:26430537

  17. WEBSLIDE: A "Virtual" Slide Projector Based on World Wide Web

    NASA Astrophysics Data System (ADS)

    Barra, Maria; Ferrandino, Salvatore; Scarano, Vittorio

    1999-03-01

    We present here the design key concepts of WEBSLIDE, a software project whose objective is to provide a simple, cheap and efficient solution for showing slides during lessons in computer labs. In fact, WEBSLIDE allows the video monitors of several client machines (the "STUDENTS") to be synchronously updated by the actions of a particular client machine, called the "INSTRUCTOR." The system is based on the World Wide Web and the software components of WEBSLIDE mainly consists in a WWW server, browsers and small Cgi-Bill scripts. What makes WEBSLIDE particularly appealing for small educational institutions is that WEBSLIDE is built with "off the shelf" products: it does not involve using a specifically designed program but any Netscape browser, one of the most popular browsers available on the market, is sufficient. Another possible use is to use our system to implement "guided automatic tours" through several pages or Intranets internal news bulletins: the company Web server can broadcast to all employees relevant information on their browser.

  18. Thermal Stress Cracking of Slide-Gate Plates in Steel Continuous Casting

    NASA Astrophysics Data System (ADS)

    Lee, Hyoung-Jun; Thomas, Brian G.; Kim, Seon-Hyo

    2016-04-01

    The slide-gate plates in a cassette assembly control the steel flow through the tundish nozzle, and may experience through-thickness cracks, caused by thermal expansion and/or mechanical constraint, leading to air aspiration and safety concerns. Different mechanisms for common and rare crack formation are investigated with the aid of a three-dimensional finite-element model of thermal mechanical behavior of the slide-gate plate assembly during bolt pretensioning, preheating, tundish filling, casting, and cooling stages. The model was validated with previous plant temperature measurements of a ladle plate during preheating and casting, and then applied to a typical tundish-nozzle slide-gate assembly. The formation mechanisms of different types of cracks in the slide-gate plates are investigated using the model and evaluated with actual slide-gate plates at POSCO. Common through-thickness radial cracks, found in every plate, are caused during casting by high tensile stress on the outside surfaces of the plates, due to internal thermal expansion. In the upper plate, these cracks may also arise during preheating or tundish filling. Excessive bolt tightening, combined with thermal expansion during casting may cause rare radial cracks in the upper and lower plates. Rare radial and transverse cracks in middle plate appear to be caused during tundish filling by impingement of molten steel on the middle of the middle plate that generates tensile stress in the surrounding refractory. The mechanical properties of the refractory, the bolt tightening conditions, and the cassette/plate design are all important to service life.

  19. X-ray photoelectron spectroscopic study of surface chemistry of dibenzyl-disulfide on steel under mild and severe wear conditions

    NASA Technical Reports Server (NTRS)

    Wheeler, D. R.

    1977-01-01

    Wear tests were performed on 304 stainless steel lubricated with pure mineral oil with and without dibenzyl-disulfide. Both mild and severe wear were observed. The type of wear was distinguished by a marked change in wear rate, friction coefficient, and wear scar appearance. The chemical composition of the wear scar surface was examined with X-ray photoelectron spectroscopy in conjunction with argon ion sputter etching. In severe wear scars, a sulfide was formed at the expense of the normal oxide layer. In mild wear scars, there were only superficial sulfur compounds, but there was a substantial increase in the oxide thickness.

  20. Humboldt slide - A large shear-dominated retrogressive slope failure

    USGS Publications Warehouse

    Gardner, J.V.; Prior, D.B.; Field, M.E.

    1999-01-01

    Humboldt Slide is a large, complex slide zone located on the northern California continental margin. Its three-dimensional architecture has been imaged by a combination of multibeam bathymetry, Huntec Deep-Tow seismic profiling, and sidescan sonar. The slide is interpreted to be Late Pleistocene to early Holocene in age and was caused by a combination of factors. The area of the slide is a local depocenter with high accumulation rates of organic-rich sediment; there has been local steepening of slopes by tectonic uplifts; and the entire area is one of high seismicity. Overall, the failure occurred by retrogressive, shear-dominated, minimum movement apparently as a sequence of events. Failure initially occurred by subsidence extension at the middle of the feature, followed by upslope retrogressive failure and downslope compression, and finally by translational sliding at the top of the slide. Degassing, as evidenced by abundant pockmarks, may have inhibited downslope translation. The slide may still be active, as suggested by offsets in Holocene hemipelagic sediment draped over some of the shear surfaces. Crown cracks occur above the present head of the failure and may represent the next generation of failure.

  1. Estimation of lung lobar sliding using image registration

    NASA Astrophysics Data System (ADS)

    Amelon, Ryan; Cao, Kunlin; Reinhardt, Joseph M.; Christensen, Gary E.; Raghavan, Madhavan

    2012-03-01

    MOTIVATION: The lobes of the lungs slide relative to each other during breathing. Quantifying lobar sliding can aid in better understanding lung function, better modeling of lung dynamics, and a better understanding of the limits of image registration performance near fissures. We have developed a method to estimate lobar sliding in the lung from image registration of CT scans. METHODS: Six human lungs were analyzed using CT scans spanning functional residual capacity (FRC) to total lung capacity (TLC). The lung lobes were segmented and registered on a lobe-by-lobe basis. The displacement fields from the independent lobe registrations were then combined into a single image. This technique allows for displacement discontinuity at lobar boundaries. The displacement field was then analyzed as a continuum by forming finite elements from the voxel grid of the FRC image. Elements at a discontinuity will appear to have undergone significantly elevated 'shear stretch' compared to those within the parenchyma. Shear stretch is shown to be a good measure of sliding magnitude in this context. RESULTS: The sliding map clearly delineated the fissures of the lung. The fissure between the right upper and right lower lobes showed the greatest sliding in all subjects while the fissure between the right upper and right middle lobe showed the least sliding.

  2. Static and dynamic friction in sliding colloidal monolayers

    NASA Astrophysics Data System (ADS)

    Vanossi, Andrea; Manini, Nicola; Tosatti, Erio

    2013-03-01

    In a recent experimental breakthrough, the controlled sliding of 2D colloidal crystals over perfectly regular, laser generated periodic or quasi-periodic `corrugation` potentials has been realized in Bechinger's group. Based on realistic MD simulations which reproduce the main experimentally observed features, we explore the potential impact of colloid monolayer sliding in nanotribology. The free motion of edge-spawned kinks and antikinks in smooth incommensurate sliding is contrasted with the kink-antikink pair nucleation at the large static friction threshold in the commensurate case. The Aubry pinning/depinning transition is also demonstrated, e.g., as a function of the corrugation amplitude. Simulated sliding data allow the extraction of frictional work directly from particles coordinates and velocities as a function of classic friction parameters, primarily speed, and corrugation strength. Analogies with sliding charge-density waves, driven Josephson systems, sliding of rare gas islands, and other novel features suggest further experiments and insights, which promote colloid sliding to a novel friction study instrument. Research partly sponsored by Sinergia Project CRSII2 136287/1.

  3. Single molecule study of a processivity clamp sliding on DNA

    SciTech Connect

    Laurence, T A; Kwon, Y; Johnson, A; Hollars, C; O?Donnell, M; Camarero, J A; Barsky, D

    2007-07-05

    Using solution based single molecule spectroscopy, we study the motion of the polIII {beta}-subunit DNA sliding clamp ('{beta}-clamp') on DNA. Present in all cellular (and some viral) forms of life, DNA sliding clamps attach to polymerases and allow rapid, processive replication of DNA. In the absence of other proteins, the DNA sliding clamps are thought to 'freely slide' along the DNA; however, the abundance of positively charged residues along the inner surface may create favorable electrostatic contact with the highly negatively charged DNA. We have performed single-molecule measurements on a fluorescently labeled {beta}-clamp loaded onto freely diffusing plasmids annealed with fluorescently labeled primers of up to 90 bases. We find that the diffusion constant for 1D diffusion of the {beta}-clamp on DNA satisfies D {le} 10{sup -14} cm{sup 2}/s, much slower than the frictionless limit of D = 10{sup -10} cm{sup 2}/s. We find that the {beta} clamp remains at the 3-foot end in the presence of E. coli single-stranded binding protein (SSB), which would allow for a sliding clamp to wait for binding of the DNA polymerase. Replacement of SSB with Human RP-A eliminates this interaction; free movement of sliding clamp and poor binding of clamp loader to the junction allows sliding clamp to accumulate on DNA. This result implies that the clamp not only acts as a tether, but also a placeholder.

  4. Melatonin versus Placebo in Children with Autism Spectrum Conditions and Severe Sleep Problems Not Amenable to Behaviour Management Strategies: A Randomised Controlled Crossover Trial

    ERIC Educational Resources Information Center

    Wright, Barry; Sims, David; Smart, Siobhan; Alwazeer, Ahmed; Alderson-Day, Ben; Allgar, Victoria; Whitton, Clare; Tomlinson, Heather; Bennett, Sophie; Jardine, Jenni; McCaffrey, Nicola; Leyland, Charlotte; Jakeman, Christine; Miles, Jeremy

    2011-01-01

    Twenty-two children with autism spectrum disorders who had not responded to supported behaviour management strategies for severe dysomnias entered a double blind, randomised, controlled crossover trial involving 3 months of placebo versus 3 months of melatonin to a maximum dose of 10 mg. 17 children completed the study. There were no significant…

  5. Predictors of Age of Diagnosis for Children with Autism Spectrum Disorder: The Role of a Consistent Source of Medical Care, Race, and Condition Severity

    ERIC Educational Resources Information Center

    Emerson, Natacha D.; Morrell, Holly E. R.; Neece, Cameron

    2016-01-01

    Having a consistent source of medical care may facilitate diagnosis of autism spectrum disorders (ASD). This study examined predictors of age of ASD diagnosis using data from the 2011-2012 National Survey of Children's Health. Using multiple linear regression analysis, age of diagnosis was predicted by race, ASD severity, having a consistent…

  6. Assessing Visual Attention in Young Children and Adolescents with Severe Mental Retardation Utilizing Conditional-Discrimination Tasks and Multiple Testing Procedures

    ERIC Educational Resources Information Center

    Huguenin, Nancy H.

    2004-01-01

    To effectively reduce overselective attention, a fine-grained analysis of the control exhibited by compound training cues is first needed. Computer software was developed in this study to administer two different stimulus control-testing procedures to assess how three young children of normal development and three adolescents with severe mental…

  7. Railway bridge monitoring during construction and sliding

    NASA Astrophysics Data System (ADS)

    Inaudi, Daniele; Casanova, Nicoletta; Kronenberg, Pascal; Vurpillot, Samuel

    1997-05-01

    The Moesa railway bridge is a composite steel concrete bridge on three spans of 30 m each. The 50 cm thick concrete deck is supported on the lower flanges of two continuous, 2.7 m high I-beams. The bridge has been constructed alongside an old metallic bridge. After demolishing this one, the new bridge has been slid for 5 m by 4 hydraulic jacks and positioned on the refurbished piles of the old bridge. About 30 fiber optic, low-coherence sensors were imbedded in the concrete deck to monitor its deformations during concrete setting and shrinkage, as well as during the bridge sliding phase. In the days following concrete pour it was possible to follow its thermal expansion due to the exothermic setting reaction and the following thermal and during shrinkage. The deformations induced by the additional load produced by the successive concreting phases were also observed. During the bridge push, which extended over six hours, the embedded and surface mounted sensors allowed the monitoring of the curvature variations in the horizontal plane due to the slightly uneven progression of the jacks. Excessive curvature and the resulting cracking of concrete could be ruled out by these measurements. It was also possible to observe the bridge elongation under the heating action of the sun.

  8. Depth Estimation Using a Sliding Camera.

    PubMed

    Ge, Kailin; Hu, Han; Feng, Jianjiang; Zhou, Jie

    2016-02-01

    Image-based 3D reconstruction technology is widely used in different fields. The conventional algorithms are mainly based on stereo matching between two or more fixed cameras, and high accuracy can only be achieved using a large camera array, which is very expensive and inconvenient in many applications. Another popular choice is utilizing structure-from-motion methods for arbitrarily placed camera(s). However, due to too many degrees of freedom, its computational cost is heavy and its accuracy is rather limited. In this paper, we propose a novel depth estimation algorithm using a sliding camera system. By analyzing the geometric properties of the camera system, we design a camera pose initialization algorithm that can work satisfyingly with only a small number of feature points and is robust to noise. For pixels corresponding to different depths, an adaptive iterative algorithm is proposed to choose optimal frames for stereo matching, which can take advantage of continuously pose-changing imaging and save the time consumption amazingly too. The proposed algorithm can also be easily extended to handle less constrained situations (such as using a camera mounted on a moving robot or vehicle). Experimental results on both synthetic and real-world data have illustrated the effectiveness of the proposed algorithm.

  9. Introducing Slide Sets for the Introductory Astronomy Instructor

    NASA Astrophysics Data System (ADS)

    Meinke, Bonnie K.; Schneider, Nicholas; Brain, David; Schultz, Gregory; Buxner, Sanlyn; Smith, Denise

    2014-11-01

    The NASA Science Mission Directorate (SMD) Science Education and Public Outreach (E/PO) community and Forums work together to bring the cutting-edge discoveries of NASA Astrophysics and Planetary Science missions to the introductory astronomy college classroom. These mission- and grant-based E/PO programs are uniquely poised to foster collaboration between scientists with content expertise and educators with pedagogy expertise. We present two new opportunities for college instructors to bring the latest NASA discoveries in Space Science into their classrooms.In an effort to keep the astronomy classroom apprised of the fast moving field of planetary science, the Division of Planetary Sciences (DPS) has developed “DPS Discoveries”, which are short, topical presentations that can be incorporated into college lectures. The slide sets are targeted at the Introductory Astronomy undergraduate level. Each slide set consists of three slides that cover a description of the discovery, a discussion of the underlying science, and a presentation of the big picture implications of the discovery, with a fourth slide that includes links to associated press releases, images, and primary sources. Topics span all subdisciplines of planetary science, and sets are available in Farsi and Spanish. The NASA SMD Planetary Science Forum has recently partnered with the DPS to continue producing the Discovery slides and connect them to NASA mission science. http://dps.aas.org/education/dpsdisc Similarly, the NASA SMD Astrophysics Forum is coordinating the development of a series of slide sets to help Astronomy 101 instructors incorporate new discoveries in their classrooms. The “Astro 101 slide sets” are presentations 5-7 slides in length on a new development or discovery from a NASA Astrophysics mission relevant to topics in introductory astronomy courses. We intend for these slide sets to help Astronomy 101 instructors include new developments (not yet in their textbooks) into the

  10. Geomorphology, stability and mobility of the Currituck slide

    USGS Publications Warehouse

    Locat, J.; Lee, H.; ten Brink, U.S.; Twichell, D.; Geist, E.; Sansoucy, M.

    2009-01-01

    Over the last 100,000??years, the U.S. Atlantic continental margin has experienced various types of mass movements some of which are believed to have taken place at times of low sea level. At one of these times of low sea level a significant trigger caused a major submarine mass movement off the coast of Virginia: the Currituck slide which is believed to have taken place between 24 and 50??ka ago. This slide removed a total volume of about 165??km3 from this section of the continental slope. The departure zone still shows a very clean surface that dips at 4?? and is only covered by a thin veneer of postglacial sediment. Multibeam bathymetric and seismic survey data suggest that this slide took place along three failures surfaces. The morphology of the source area suggests that the sediments were already at least normally consolidated at the time of failure. The slide debris covers an area as much as 55??km wide that extends 180??km from the estimated toe of the original slope. The back analysis of slide initiation indicates that very high pore pressure, a strong earthquake, or both had to be generated to trigger slides on such a low failure plane angle. The shape of the failure plane, the fact that the surface is almost clear of any debris, and the mobility analysis, all support the argument that the slides took place nearly simultaneously. Potential causes for the generation of high pore pressures could be seepage forces from coastal aquifers, delta construction and related pore pressure generation due to the local sediment loading, gas hydrates, and earthquakes. This slide, and its origin, is a spectacular example of the potential threat that submarine mass movements can pose to the US Atlantic coast and underline the need to further assess the potential for the generation of such large slides, like the Grand Banks 1927 landslide of similar volume. ?? 2008 Elsevier B.V.

  11. Comparing whole slide digital images versus traditional glass slides in the detection of common microscopic features seen in dermatitis

    PubMed Central

    Vyas, Nikki S.; Markow, Michael; Prieto-Granada, Carlos; Gaudi, Sudeep; Turner, Leslie; Rodriguez-Waitkus, Paul; Messina, Jane L.; Jukic, Drazen M.

    2016-01-01

    Background: The quality and limitations of digital slides are not fully known. We aimed to estimate intrapathologist discrepancy in detecting specific microscopic features on glass slides and digital slides created by scanning at ×20. Methods: Hematoxylin and eosin and periodic acid–Schiff glass slides were digitized using the Mirax Scan (Carl Zeiss Inc., Germany). Six pathologists assessed 50–71 digital slides. We recorded objective magnification, total time, and detection of the following: Mast cells; eosinophils; plasma cells; pigmented macrophages; melanin in the epidermis; fungal bodies; neutrophils; civatte bodies; parakeratosis; and sebocytes. This process was repeated using the corresponding glass slides after 3 weeks. The diagnosis was not required. Results: The mean time to assess digital slides was 176.77 s and 137.61 s for glass slides (P < 0.001, 99% confidence interval [CI]). The mean objective magnification used to detect features using digital slides was 18.28 and 14.07 for glass slides (P < 0.001, 99.99% CI). Parakeratosis, civatte bodies, pigmented macrophages, melanin in the epidermis, mast cells, eosinophils, plasma cells, and neutrophils, were identified at lower objectives on glass slides (P = 0.023–0.001, 95% CI). Average intraobserver concordance ranged from κ = 0.30 to κ = 0.78. Features with poor to fair average concordance were: Melanin in the epidermis (κ = 0.15–0.58); plasma cells (κ = 0.15–0.49); and neutrophils (κ = 0.12–0.48). Features with moderate average intrapathologist concordance were: parakeratosis (κ = 0.21–0.61); civatte bodies (κ = 0.21–0.71); pigment-laden macrophages (κ = 0.34–0.66); mast cells (κ = 0.29–0.78); and eosinophils (κ = 0.31–0.79). The average intrapathologist concordance was good for sebocytes (κ = 0.51–1.00) and fungal bodies (κ = 0.47–0.76). Conclusions: Telepathology using digital slides scanned at ×20 is sufficient for detection of histopathologic features routinely

  12. FASTGRASS: A mechanistic model for the prediction of Xe, I, Cs, Te, Ba, and Sr release from nuclear fuel under normal and severe-accident conditions

    SciTech Connect

    Rest, J.; Zawadzki, S.A. )

    1992-09-01

    The primary physical/chemical models that form the basis of the FASTGRASS mechanistic computer model for calculating fission-product release from nuclear fuel are described. Calculated results are compared with test data and the major mechanisms affecting the transport of fission products during steady-state and accident conditions are identified.

  13. Retrogressive Failures in Sand Deposits of the Mississippi River. Report 2. Empirical Evidence in Support of the Hypothesized Failure Mechanism and Development of the Levee Safety Flow Slide Monitoring System

    DTIC Science & Technology

    1988-06-01

    30 Empirical Evidence of a Runout Angle ............................... 30 NOD Levee Safety Flow Slide Monitoring System ...................... 51...14 illustrates the retrogression mechanism. Two most important questions relative to the runout angle concept are: a. Is there empirical evidence...ranging variable for flow slides below Baton Rouge? Empirical Evidence of a Runout Angle 19. For several years the author was involved in the

  14. Sliding mode control for chaotic systems based on LMI

    NASA Astrophysics Data System (ADS)

    Wang, Hua; Han, Zheng-zhi; Xie, Qi-yue; Zhang, Wei

    2009-04-01

    This paper investigates the chaos control problem for a general class of chaotic systems. A feedback controller is established to guarantee asymptotical stability of the chaotic systems based on the sliding mode control theory. A new reaching law is introduced to solve the chattering problem that is produced by traditional sliding mode control. A dynamic compensator is designed to improve the performance of the closed-loop system in sliding mode, and its parameter is obtained from a linear matrix inequality (LMI). Simulation results for the well known Chua's circuit and Lorenz chaotic system are provided to illustrate the effectiveness of the proposed scheme.

  15. A relationship between slide quality and image quality in whole slide imaging (WSI).

    PubMed

    Yagi, Yukako; Gilbertson, John R

    2008-07-15

    This study examined the effect of tissue section thickness and consistency--parameters outside the direct control of the imaging devices themselves--on WSI capture speed and image quality. Preliminary data indicates that thinner, more consistent tissue sectioning (such as those produced by automated tissue sectioning robots) results in significantly faster WSI capture times and better image quality. A variety of tissue types (including human breast, mouse embryo, mouse brain, etc.) were sectioned using an (AS-200) Automated Tissue Sectioning System (Kurabo Industries, Osaka Japan) at thicknesses from 2 - 9 microm (at one microm intervals) and stained with H&E by a standard method. The resulting slides were imaged with 5 different WSI devices (ScanScope CS, Aperio, CA; iScan, BioImagene, CA; DX40, DMetrix, AZ; NanoZoomer, Hamamatsu Photonics K.K., Japan; Mirax Scan, Carl Zeiss Inc., Germany) with sampling periods of 0.43 - 0.69 microm/pixel. Slides with different tissue thicknesses were compared for image quality, appropriate number of focus points, and overall scanning speed. Thinner sections (i.e. 3 microm sections versus 7 microm) required significantly fewer focus points and had significantly lower (10-15%) capture times. Improvement was seen with all devices and tissues tested. Furthermore, a panel of experienced pathologist judged image quality to be significantly better (for example, with better apparent resolution of nucleoli) with the thinner sections. Automated tissue sectioning is a very new technology; however, the AS-200 seems to be able to produce thinner, more consistent, flatter sections than manual methods at reasonably high throughput. The resulting tissue sections seem to be easier for a WSI system's focusing systems to deal with (compared to manually cut slides). Teaming an automated tissue-sectioning device with a WSI device shows promise in producing faster WSI throughput with better image quality.

  16. Automated detection of diagnostically relevant regions in H&E stained digital pathology slides

    NASA Astrophysics Data System (ADS)

    Bahlmann, Claus; Patel, Amar; Johnson, Jeffrey; Ni, Jie; Chekkoury, Andrei; Khurd, Parmeshwar; Kamen, Ali; Grady, Leo; Krupinski, Elizabeth; Graham, Anna; Weinstein, Ronald

    2012-03-01

    We present a computationally efficient method for analyzing H&E stained digital pathology slides with the objective of discriminating diagnostically relevant vs. irrelevant regions. Such technology is useful for several applications: (1) It can speed up computer aided diagnosis (CAD) for histopathology based cancer detection and grading by an order of magnitude through a triage-like preprocessing and pruning. (2) It can improve the response time for an interactive digital pathology workstation (which is usually dealing with several GByte digital pathology slides), e.g., through controlling adaptive compression or prioritization algorithms. (3) It can support the detection and grading workflow for expert pathologists in a semi-automated diagnosis, hereby increasing throughput and accuracy. At the core of the presented method is the statistical characterization of tissue components that are indicative for the pathologist's decision about malignancy vs. benignity, such as, nuclei, tubules, cytoplasm, etc. In order to allow for effective yet computationally efficient processing, we propose visual descriptors that capture the distribution of color intensities observed for nuclei and cytoplasm. Discrimination between statistics of relevant vs. irrelevant regions is learned from annotated data, and inference is performed via linear classification. We validate the proposed method both qualitatively and quantitatively. Experiments show a cross validation error rate of 1.4%. We further show that the proposed method can prune ~90% of the area of pathological slides while maintaining 100% of all relevant information, which allows for a speedup of a factor of 10 for CAD systems.

  17. Slide Conveying of Granular Materials-Thinking Out of the Glovebox

    NASA Technical Reports Server (NTRS)

    Goddard, J. D.; Didwania, A. K.; Nott, P. R.

    2000-01-01

    The vibratory conveyor, routinely employed for normal-gravity transport of granular materials, usually consists of a continuous open trough vibrated sinusoidally to induce axial movement of a granular material. Motivated in part by a hypothetical application in zero gravity, we propose a novel modification of the vibratory conveyor based on a closed 2d trough operating in a "slide-conveying" mode, with the granular mass remaining permanently in contact with the trough walls. We present a detailed analysis of the mechanics of transport, based on a rigid-slab model for the granular mass with frictional (Coulomb) slip at the upper and lower walls. The form of the vibration cycle plays a crucial role, and the optimal conveying cycle is not the commonly assumed rectilinear sinusoidal motion. The conveying efficiency for the novel slide conveyor will be presented for several simple vibration cycles, including one believed to represent the theoretical optimum.

  18. Student Teachers' Evaluations of Slides of Children with Down Syndrome: Impact of Facial Plastic Surgery, Labelling and Factual Knowledge.

    ERIC Educational Resources Information Center

    Elkabetz, R.; And Others

    1990-01-01

    This study examined the impact of facial plastic surgery, labeling (mentally retarded, normal, Down's syndrome), and level of knowledge of Down's syndrome on 127 student teachers' evaluations of slides of persons with such characteristics. Although there was no overall significant main effect for the pre-post operation condition, there was a…

  19. Preliminary evaluation of feeder and lint slide moisture addition on ginning, fiber quality, and textile processing of western cotton

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this study was to evaluate the effects of moisture addition at the gin stand feeder conditioning hopper and/or the battery condenser slide on gin performance and Western cotton fiber quality and textile processing. The test treatments included no moisture addition, feeder hopper hum...

  20. Static and kinetic friction force and surface roughness of different archwire-bracket sliding contacts.

    PubMed

    Carrion-Vilches, Francisco J; Bermudez, María-Dolores; Fructuoso, Paula

    2015-01-01

    The aim of this study was to determine the static and kinetic friction forces of the contact bracket-archwire with different dental material compositions in order to select those materials with lower resistance to sliding. We carried out sliding friction tests by means of a universal testing machine following an experimental procedure as described in ASTM D1894 standard. We determined the static and kinetic friction forces under dry and lubricating conditions using an artificial saliva solution at 36.5ºC. The bracket-archwire pairs studied were: stainless steel-stainless steel; stainless steel-glass fiber composite; stainless steel-Nitinol 60; sapphire-stainless steel; sapphire-glass fiber composite; and sapphire-Nitinol 60. The best performance is obtained for Nitinol 60 archwire sliding against a stainless steel bracket, both under dry and lubricated conditions. These results are in agreement with the low surface roughness of Nitinol 60 with respect to the glass fiber composite archwire. The results described here contribute to establishing selection criteria for materials for dental archwire-brackets.

  1. The Evolution of Interfacial Sliding Stresses During Cyclic Push-in Testing of C- and BN-Coated Hi-Nicalon Fiber-Reinforced CMCs

    NASA Technical Reports Server (NTRS)

    Eldridge, J. I.; Bansal, N. P.; Bhatt, R. T.

    1998-01-01

    Interfacial debond cracks and fiber/matrix sliding stresses in ceramic matrix composites (CMCs) can evolve under cyclic fatigue conditions as well as with changes in the environment, strongly affecting the crack growth behavior, and therefore, the useful service lifetime of the composite. In this study, room temperature cyclic fiber push-in testing was applied to monitor the evolution of frictional sliding stresses and fiber sliding distances with continued cycling in both C- and BN-coated Hi-Nicalon SiC fiber-reinforced CMCs. A SiC matrix composite reinforced with C-coated Hi-Nical on fibers as well as barium strontium aluminosilicate (BSAS) matrix composites reinforced with BN-coated (four different deposition processes compared) Hi-Nicalon fibers were examined. For failure at a C interface, test results indicated progressive increases in fiber sliding distances during cycling in room air but not in nitrogen. These results suggest the presence of moisture will promote crack growth when interfacial failure occurs at a C interface. While short-term testing environmental effects were not apparent for failure at the BN interfaces, long-term exposure of partially debonded BN-coated fibers to humid air resulted in large increases in fiber sliding distances and decreases in interfacial sliding stresses for all the BN coatings, presumably due to moisture attack. A wide variation was observed in debond and frictional sliding stresses among the different BN coatings.

  2. Sliding Motility, Biofilm Formation, and Glycopeptidolipid Production in Mycobacterium colombiense Strains

    PubMed Central

    Maya-Hoyos, Milena; Leguizamón, John; Mariño-Ramírez, Leonardo; Soto, Carlos Y.

    2015-01-01

    Mycobacterium colombiense is a novel member of the Mycobacterium avium complex, which produces respiratory and disseminated infections in immunosuppressed patients. Currently, the morphological and genetic bases underlying the phenotypic features of M. colombiense strains remain unknown. In the present study, we demonstrated that M. colombiense strains displaying smooth morphology show increased biofilm formation on hydrophobic surfaces and sliding on motility plates. Thin-layer chromatography experiments showed that M. colombiense strains displaying smooth colonies produce large amounts of glycolipids with a chromatographic behaviour similar to that of the glycopeptidolipids (GPLs) of M. avium. Conversely, we observed a natural rough variant of M. colombiense (57B strain) lacking pigmentation and exhibiting impaired sliding, biofilm formation, and GPL production. Bioinformatics analyses revealed a gene cluster that is likely involved in GPL biosynthesis in M. colombiense CECT 3035. RT-qPCR experiments showed that motile culture conditions activate the transcription of genes possibly involved in key enzymatic activities of GPL biosynthesis. PMID:26180799

  3. Optimization of fluoroimmunoassay against C-reactive protein exploiting immobilized-antigen glass slide.

    PubMed

    Kim, Namsoo; Cho, Yong-Jin

    2013-03-01

    An optimization experiment for an indirect-competitive (IC) fluoroimmunoassay (FIA) against C-reactive protein (CRP) was conducted exploiting an immobilized-antigen glass slide and an anti-CRP antibody tagged with fluorescent silica nanoparticles (FSNPs). The optimized conditions for the IC FIA were as follows: time and concentration of treatment with glutaraldehyde, 30 min and 1.5%, respectively; time of reaction with coating antigen and concentration of coating antigen for immobilization, 1 h and 0.1 mg/mL, respectively; concentration of FSNP-anti-CRP antibody conjugate coupled by the biotin-avidin interaction, the bioconjugate, for immune reaction, 0.250 mg/mL; concentration of bovine serum albumin (BSA) for blocking and time of blocking with BSA, 3% and 30 min, respectively. By using the glass slide, a highly sensitive detection against CRP was possible with the limit of detection below 0.1 ng/mL.

  4. Implementation of fuzzy-sliding mode based control of a grid connected photovoltaic system.

    PubMed

    Menadi, Abdelkrim; Abdeddaim, Sabrina; Ghamri, Ahmed; Betka, Achour

    2015-09-01

    The present work describes an optimal operation of a small scale photovoltaic system connected to a micro-grid, based on both sliding mode and fuzzy logic control. Real time implementation is done through a dSPACE 1104 single board, controlling a boost chopper on the PV array side and a voltage source inverter (VSI) on the grid side. The sliding mode controller tracks permanently the maximum power of the PV array regardless of atmospheric condition variations, while The fuzzy logic controller (FLC) regulates the DC-link voltage, and ensures via current control of the VSI a quasi-total transit of the extracted PV power to the grid under a unity power factor operation. Simulation results, carried out via Matlab-Simulink package were approved through experiment, showing the effectiveness of the proposed control techniques.

  5. Dynamic boundary layer based neural network quasi-sliding mode control for soft touching down on asteroid

    NASA Astrophysics Data System (ADS)

    Liu, Xiaosong; Shan, Zebiao; Li, Yuanchun

    2017-04-01

    Pinpoint landing is a critical step in some asteroid exploring missions. This paper is concerned with the descent trajectory control for soft touching down on a small irregularly-shaped asteroid. A dynamic boundary layer based neural network quasi-sliding mode control law is proposed to track a desired descending path. The asteroid's gravitational acceleration acting on the spacecraft is described by the polyhedron method. Considering the presence of input constraint and unmodeled acceleration, the dynamic equation of relative motion is presented first. The desired descending path is planned using cubic polynomial method, and a collision detection algorithm is designed. To perform trajectory tracking, a neural network sliding mode control law is given first, where the sliding mode control is used to ensure the convergence of system states. Two radial basis function neural networks (RBFNNs) are respectively used as an approximator for the unmodeled term and a compensator for the difference between the actual control input with magnitude constraint and nominal control. To improve the chattering induced by the traditional sliding mode control and guarantee the reachability of the system, a specific saturation function with dynamic boundary layer is proposed to replace the sign function in the preceding control law. Through the Lyapunov approach, the reachability condition of the control system is given. The improved control law can guarantee the system state move within a gradually shrinking quasi-sliding mode band. Numerical simulation results demonstrate the effectiveness of the proposed control strategy.

  6. Contribution of fine filler particles to energy dissipation during wet sliding of elastomer compounds on a rough surface

    NASA Astrophysics Data System (ADS)

    Pan, Xiao-Dong

    2007-08-01

    Elastomer compounds reinforced with precipitated silica can exhibit elevated wet sliding friction on a rough surface in comparison with corresponding compounds filled with carbon black particles. The underlying mechanism is currently not well understood. To unravel this puzzling observation, the variation of wet sliding friction with filler volume fraction is examined at the sliding speed of the order of 1 m s-1 under different lubrication conditions. Depending on the lubrication liquid—water or ethanol—a compound that shows both higher bulk hysteretic loss and lower modulus does not always exhibit a higher wet sliding friction. A thorough characterization of the bulk rheology of the compounds investigated fails to provide the rationale for such behaviour, thus constituting an apparent violation of the conventional viscoelastic understanding of rubber friction on a rough surface. On the other hand, the detected lowering of friction when the lubrication liquid is changed from water to ethanol resembles the effect of liquid medium on interfacial adhesion reported in the literature. Hence, it is suggested that a stronger interfacial attractive interaction should exist in water between the road surface and silica particles on the compound surface immediately next to the road surface. This should be related to the elevated wet sliding friction detected for silica-filled compounds under water lubrication.

  7. Effects of severity of post-flowering leaf removal on berry growth and composition of three red Vitis vinifera L. cultivars grown under semiarid conditions.

    PubMed

    Kotseridis, Yorgos; Georgiadou, Afroditi; Tikos, Panagiotis; Kallithraka, Stamatina; Koundouras, Stefanos

    2012-06-13

    The effects of the severity of post-flowering leaf removal on the growth and phenolic composition of berry skin and seeds were studied in three Vitis vinifera L. genotypes over two consecutive seasons, 2007 and 2008. The study was conducted in a commercial vertical shoot positioned (VSP)-trained nonirrigated vineyard of northern Greece, planted with cultivars Merlot, Cabernet Sauvignon, and Sangiovese. Three different severities of leaf removal in the fruit zone were applied manually at berry set: nondefoliated (ND), removal of the lateral shoots of the first six basal nodes (LR), and full removal of the total leaf area (main leaves and lateral shoots) of the first six basal nodes (FR). Grape samples were obtained at commercial harvest. Leaf removal decreased yield per vine and cluster weight in Merlot and Sangiovese. Cluster compactness was reduced with the severity of defoliation only in Merlot, due to a decrease in berry number per cluster; berry fresh weight was unaffected in both cultivars. On the contrary, in Cabernet Sauvignon, yield was unaffected but berry size was restrained by leaf removal. Skin and seed mass followed variations in berry mass (except for seed mass in Sangiovese). Fruit zone leaf removal did not affect must soluble solids and increased titratable acidity only in Merlot. Defoliation increased skin anthocyanins in Merlot and Cabernet Sauvignon in the order FR > LR > ND but significantly reduced seed flavan-3-ols mainly as a result of the reduction in catechin and epicatechin amount. For these varieties, FR had lower seed flavan-3-ols than ND in both varieties, whereas LR had intermediate values. However, in Sangiovese, the highest seed phenolic content was recorded in LR. The results showed that post-flowering leaf removal improved the overall berry composition in Merlot and Cabernet Sauvignon but had limited effect in Sangiovese.

  8. Finding Frequent Closed Itemsets in Sliding Window in Linear Time

    NASA Astrophysics Data System (ADS)

    Chen, Junbo; Zhou, Bo; Chen, Lu; Wang, Xinyu; Ding, Yiqun

    One of the most well-studied problems in data mining is computing the collection of frequent itemsets in large transactional databases. Since the introduction of the famous Apriori algorithm [14], many others have been proposed to find the frequent itemsets. Among such algorithms, the approach of mining closed itemsets has raised much interest in data mining community. The algorithms taking this approach include TITANIC [8], CLOSET+[6], DCI-Closed [4], FCI-Stream [3], GC-Tree [15], TGC-Tree [16] etc. Among these algorithms, FCI-Stream, GC-Tree and TGC-Tree are online algorithms work under sliding window environments. By the performance evaluation in [16], GC-Tree [15] is the fastest one. In this paper, an improved algorithm based on GC-Tree is proposed, the computational complexity of which is proved to be a linear combination of the average transaction size and the average closed itemset size. The algorithm is based on the essential theorem presented in Sect. 4.2. Empirically, the new algorithm is several orders of magnitude faster than the state of art algorithm, GC-Tree.

  9. Spalling behavior of Cu plate under sliding detonation loading

    NASA Astrophysics Data System (ADS)

    Fan, Cheng; Liu, Mingtao; Guo, Zhaoliang; Tang, Tiegang

    2017-01-01

    We study the fracture behavior of a Cu plate under sliding detonation loading using wire explosion technique. Both Doppler Pins Systems (DPS) and Scanning Electron Microscope (SEM) are employed in the experiments to study the velocity of the free surface and the microstructure of the recovered samples. A novel spalling phenomenon is substantially observed. Unlike the flyer impact method, the typical spalling signals are not currently obtained in the velocity curves. But the microstructure images of recovered samples show obvious spalling characters. Several micro-holes are created and arranged along the direction perpendicular to the loading axis. Moreover, these holes all aline within a wide band with about 1mm width. This is quite different from the case in the flyer impact experiment, in which the microholes all aline in a very narrow region. This is caused by the complex tensile stress state in the sample initiated by the explosive loading. More interestingly, all the microholes are initiated at the grain boundary and the grain size is much smaller in the band, especially at the edge of the big holes. These results may reveal the mechanism of the nucleation and the growth process for the microholes.

  10. 11. COULTERVILLE ROAD AT ROCK SLIDE AREA WITH HWY 140 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. COULTERVILLE ROAD AT ROCK SLIDE AREA WITH HWY 140 AT REAR. LOOKING NNE. GIS: N-37 43 04.7 / W-119 43 00.3 - Coulterville Road, Between Foresta & All-Weather Highway, Yosemite Village, Mariposa County, CA

  11. Sliding mode control application in ABWR plant pressure regulation

    SciTech Connect

    Huang, Zhengyu; Edwards, Robert M.

    2002-07-01

    A sliding mode controller is designed for an ABWR nuclear power plant turbine throttle pressure regulation. To avoid chattering problem, which is common to conventional sliding mode controllers, and estimation of uncertainties and disturbances, the recursive-form sliding mode control algorithm is developed. To apply the sliding mode control technique, the original plant's 11.-order dynamics model is first transformed to a canonical form differential equation of a relative order of 2 for turbine throttle pressure's dynamics. Simulation results show that the design objectives are achieved and the resulting controller is superior to the existing PI controller in many aspects, including settling time, overshoot/undershoot in response to setpoint step input and fluctuation amplitude in the presence of external disturbances. (authors)

  12. Directional sliding of histone octamers caused by DNA bending

    NASA Astrophysics Data System (ADS)

    Wang, Peng-Ye; Li, Wei; Dou, Shuo-Xing; Xie, Ping

    2006-03-01

    Chromatin-remodeling complexes such as SWI/SNF and RSC of yeast can perturb the structure of nucleosomes in an ATP-dependent manner. Experimental results prove that this chromatin remodeling process involves DNA bending. We simulate the effect of DNA bending, caused by chromatin-remodeling complexes, on directional sliding of histone octamers by Brownian dynamics simulation. The simulation results show that, after a DNA loop being generated at the side of a nucleosome, the histone octamer slides towards this DNA loop until the loop disappears. The DNA loop size is an important factor affecting the process of directional sliding of the histone octamer. A model for directional sliding of histone octamers induced by chromatin-remodeling complexes is suggested. (This research was supported by National Natural Science Foundation of China, and the Innovation Project of the Chinese Academy of Sciences.) (Email: pywang@aphy.iphy.ac.cn)

  13. 9. Bronze slide expansion plate at Pier 3, on right, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Bronze slide expansion plate at Pier 3, on right, fixed end left. - Monongahela Connecting Railroad Company, Hot Metal Bridge, Spanning Monongahela River at mile post 3.1, Pittsburgh, Allegheny County, PA

  14. QUALITY ASSESSMENT OF CONFOCAL MICROSCOPY SLIDE-BASED SYSTEMS: INSTABLITY

    EPA Science Inventory

    Background: All slide-based fluorescence cytometry detections systems basically include an excitation light source, intermediate optics, and a detection device (CCD or PMT). Occasionally, this equipment becomes unstable, generating unreliable and inferior data. Methods: A num...

  15. AFRD WAREHOUSE, SOUTH SIDE DETAIL, SLIDING DOORS. FACING NORTH. COMPARE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AFRD WAREHOUSE, SOUTH SIDE DETAIL, SLIDING DOORS. FACING NORTH. COMPARE WITH FIGURES 4 AND 5 IN NARRATIVE REPORT, WHICH SHOW DIAGONAL BRACES BELOW GLAZED SECTION OF DOORS. - Minidoka Relocation Center Warehouse, 111 South Fir Street, Shoshone, Lincoln County, ID

  16. DETAIL OF WEST END SLIDING DOOR AND EAVE VENTS ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF WEST END SLIDING DOOR AND EAVE VENTS ON THE SOUTH SIDE - Hickam Field, Practice Bomb Loading Shed, Bomb Storage Road near the intersection of Moffet and Kamakahi Streets, Honolulu, Honolulu County, HI

  17. Digitization of photographic slides: simple, effective, fast, and inexpensive method.

    PubMed

    Camarena, Lázaro Cárdenas; Guerrero, María Teresa

    2002-03-01

    The technological evolution has changed multiple areas of plastic surgery, including photography. The photograph is one of the instruments used most by the plastic surgeon, and it cannot be eliminated by technological changes. The principal change in photography is that images can be scanned through digital cameras instead of slides. Despite the multiple advantages that digital photography represents, many surgeons are resisting the change. One of the main reasons for this resistance is the large quantity of photographic slides that need to be digitized to be used at scientific conferences as well as in publications. The methods and existing techniques for digitizing slides are costly and time-consuming, and there is risk for loss of definition and image brightness. The authors present a simple, effective, fast, and inexpensive method for digitizing slides. This method has been validated by various plastic surgeons and is effective for use in multimedia presentations and for paper printouts with publication quality.

  18. BASEMENT, A view looking southwest toward the three panel, sliding ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BASEMENT, A view looking southwest toward the three panel, sliding glass door of walk-in hood and dial guage - Department of Energy, Mound Facility, Hydrolysis House Building (HH Building), One Mound Road, Miamisburg, Montgomery County, OH

  19. 6. Main cabin, northwest "wing" with plank door and sliding ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Main cabin, northwest "wing" with plank door and sliding screen door; view to east. - M.T. & Jennie H. Deaton Property, Big Springs Summer Home Area, Lot 2, Block N, Island Park, Fremont County, ID

  20. Sliding Mode Thermal Control System for Space Station Furnace Facility

    NASA Technical Reports Server (NTRS)

    Jackson Mark E.; Shtessel, Yuri B.

    1998-01-01

    The decoupled control of the nonlinear, multiinput-multioutput, and highly coupled space station furnace facility (SSFF) thermal control system is addressed. Sliding mode control theory, a subset of variable-structure control theory, is employed to increase the performance, robustness, and reliability of the SSFF's currently designed control system. This paper presents the nonlinear thermal control system description and develops the sliding mode controllers that cause the interconnected subsystems to operate in their local sliding modes, resulting in control system invariance to plant uncertainties and external and interaction disturbances. The desired decoupled flow-rate tracking is achieved by optimization of the local linear sliding mode equations. The controllers are implemented digitally and extensive simulation results are presented to show the flow-rate tracking robustness and invariance to plant uncertainties, nonlinearities, external disturbances, and variations of the system pressure supplied to the controlled subsystems.

  1. 21. INTERIOR OF SOUTHEAST REAR BEDROOM SHOWING ALUMINUMFRAME SLIDING GLASS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. INTERIOR OF SOUTHEAST REAR BEDROOM SHOWING ALUMINUM-FRAME SLIDING GLASS WINDOWS. VIEW TO SOUTHEAST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  2. 19. INTERIOR OF NORTHEAST REAR BEDROOM SHOWING ALUMINUMFRAME SLIDING GLASS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. INTERIOR OF NORTHEAST REAR BEDROOM SHOWING ALUMINUM-FRAME SLIDING GLASS WINDOWS. VIEW TO NORTHEAST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  3. An Inexpensive, Easy to Build Slide-Tape Programmer

    ERIC Educational Resources Information Center

    Lukas, Terrence

    1975-01-01

    This article discusses the construction and use of a slide/tape programer that is simple to build and use, costs a fraction of the cheapest commercial models, and can be used with any tape recorder/player. (Author)

  4. AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON SOUTH SIDE OF SOUTH WING. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  5. AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AUTOMOTIVE REPAIR SHOP, SLIDING DOOR LEADING TO BOILER ROOM ON SOUTH SIDE OF SOUTH WING, WITH SCALE. - Cedar City Automotive Repair Shop, Automotive Repair Shop, 820 North Main Street, Cedar City, Iron County, UT

  6. Hierarchical Fuzzy Feature Similarity Combination for Presentation Slide Retrieval

    NASA Astrophysics Data System (ADS)

    Kushki, A.; Ajmal, M.; Plataniotis, K. N.

    2009-12-01

    This paper proposes a novel XML-based system for retrieval of presentation slides to address the growing data mining needs in presentation archives for educational and scholarly settings. In particular, contextual information, such as structural and formatting features, is extracted from the open format XML representation of presentation slides. In response to a textual user query, each extracted feature is used to compute a fuzzy relevance score for each slide in the database. The fuzzy scores from the various features are then combined through a hierarchical scheme to generate a single relevance score per slide. Various fusion operators and their properties are examined with respect to their effect on retrieval performance. Experimental results indicate a significant increase in retrieval performance measured in terms of precision-recall. The improvements are attributed to both the incorporation of the contextual features and the hierarchical feature combination scheme.

  7. 17. Sliding access doors typical of those covering opening to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Sliding access doors typical of those covering opening to filtration bed. - Lake Whitney Water Filtration Plant, Filtration Plant, South side of Armory Street between Edgehill Road & Whitney Avenue, Hamden, New Haven County, CT

  8. 32. DETAIL OF CONCRETE TOWER AND SLIDE GATE LIFTING GEARS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. DETAIL OF CONCRETE TOWER AND SLIDE GATE LIFTING GEARS ON HEADWORKS OF DEER FLAT LOW LINE CANAL ON LOWER EMBANKMENT. VIEW TO SOUTHEAST. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  9. 13. DETAIL OF CONCRETE TOWER AND SLIDE GATE LIFTING GEARS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. DETAIL OF CONCRETE TOWER AND SLIDE GATE LIFTING GEARS ON HEADWORKS OF DEER FLAT NAMPA CANAL ON UPPER EMBANKMENT. VIEW TO SOUTHWEST. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  10. [Morphology of fungi in the slides prepared from esophageal balloons].

    PubMed

    Liu, S F

    1986-01-01

    1,762 cases were selected at random from 17,000 persons screened by esophageal balloon in 4 communes of Linxian County. The morphologic appearance of fungi was studied in 4 slides of each case selected. According to the shape of clumps formed by fungi and bacteria in the slides, morphologic 4 types were seen: cotton-like, camel hair-like, hair-like and tree-branch-like. In the preliminary microscopic analysis, the following species of fungi were noted: Candida, Leptothrix, Actinomyces, Alternaria, Fusarium and Penicillium. Some of the fungi in the slides may have been taken from the oral or pharyngeal cavity, which may be due to, at least in part, the poor oral hygiene in the population examined. A positive association was shown between the quantity of fungi in the slides and the esophageal epithelial dysplasia and carcinoma, but its biological significance should be studied further.

  11. 50. HYDRAULIC SLIDE GATE HOISTS (MANUFACTURED BY JOSHUA HENDRY IRON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. HYDRAULIC SLIDE GATE HOISTS (MANUFACTURED BY JOSHUA HENDRY IRON WORKS, SAN FRANCISCO) FOR POWER PENSTOCKS IN MACHINERY CHAMBER ON GALLERY 4 (LOCATED AT C ON SITE PLAN). VIEW TO WEST. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  12. Pulmonary Interstitial Glycogenosis: A Reversible Underlying Condition Associated With D-Transposition of the Great Arteries and Severe Persistent Pulmonary Hypertension.

    PubMed

    Sanchez-de-Toledo, Joan; González-Peris, Sebastià; Gran, Ferran; Gregoraci, Angela; Ferreres, Joan Carles; Ruiz, Cèsar W; Balcells, Joan; Abella, Raul F

    2015-07-01

    Transposition of the great arteries with intact ventricular septum and persistent pulmonary hypertension (TGA-IVS PPHN) is a rare association with a poor prognosis. We report the case of a term newborn with TGA-IVS PPHN successfully managed with perioperative extracorporeal membrane oxygenation (ECMO) and aggressive pulmonary vasodilation therapy that underwent successful arterial switch procedure. A lung biopsy obtained during the surgical procedure showed pulmonary interstitial glycogenosis, a reversible condition. Concerns over left ventricle deconditioning after ECMO could be minimized with appropriate management and monitoring of the ductus arteriosus and appropriate timing of surgery.

  13. Enhanced fluorescence cell imaging with metal-coated slides

    NASA Astrophysics Data System (ADS)

    Le Moal, Eric; Fort, Emmanuel; Lévêque-Fort, Sandrine; Janin, Anne; Murata, Hideyuki; Cordelières, Fabrice P.

    2007-07-01

    The last decade has witnessed momentous advances in fluorescence microscopy. The introduction of novel fluorescent markers, together with the development of original microscopy techniques, made it possible to study biomolecular interactions in living cells and to examine the structure and function of living tissues. The emergence of these innovative techniques had a remarkable impact on all the life sciences. However, many biological and medical applications involve the detection of minute quantities of biomolecules, and are limited by the signal weakness in common observation conditions. Here, we show that silver and gold-coated microscope slides can be used as mirror substrates to efficiently improve detection sensitivity when fluorescence microscopy is applied to micrometer-thick biological samples. We report a fourfold enhancement of the fluorescence signal and a noticeable strengthening of the image contrast, when mirror substrates are used with standard air microscope objectives. We demonstrate that metal-coated substrates provide the means to get sensitivity-enhanced fluorescence detection with dry optics, while keeping a wide field observation and a large depth of field. This is a crucial advantage for automated and high-throughput applications to cell and tissue diagnostic analysis.

  14. Grooved organogel surfaces towards anisotropic sliding of water droplets.

    PubMed

    Zhang, Pengchao; Liu, Hongliang; Meng, Jingxin; Yang, Gao; Liu, Xueli; Wang, Shutao; Jiang, Lei

    2014-05-21

    Periodic micro-grooved organogel surfaces can easily realize the anisotropic sliding of water droplets attributing to the formed slippery water/oil/solid interface. Different from the existing anisotropic surfaces, this novel surface provides a versatile candidate for the anisotropic sliding of water droplets and might present a promising way for the easy manipulation of liquid droplets for water collection, liquid-directional transportation, and microfluidics.

  15. Adaptive sliding mode control for a class of chaotic systems

    NASA Astrophysics Data System (ADS)

    Farid, R.; Ibrahim, A.; Zalam, B.

    2015-03-01

    Chaos control here means to design a controller that is able to mitigating or eliminating the chaos behavior of nonlinear systems that experiencing such phenomenon. In this paper, an Adaptive Sliding Mode Controller (ASMC) is presented based on Lyapunov stability theory. The well known Chua's circuit is chosen to be our case study in this paper. The study shows the effectiveness of the proposed adaptive sliding mode controller.

  16. 1. Photographic copy of a slide of a postcard (ca ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photographic copy of a slide of a postcard (ca 1939). Slide in possession of Mary P. Davis, Preservation Planning, Redevelopment Division, City of Albuquerque, New Mexico. EAST-NORTHEAST VIEW OF ENTRANCE GATE AND THE ORIGINAL ORPHANAGE BUILDING, BETWEEN THE CLASSROOM DORMITORY ADDITION (ON FAR SIDE) AND THE CHAPEL ADDITION (ON THE NEAR SIDE). - St. Anthony's Orphanage, 1500 Indian School Road, Northwest, Albuquerque, Bernalillo County, NM

  17. An adaptive sliding mode control technology for weld seam tracking

    NASA Astrophysics Data System (ADS)

    Liu, Jie; Hu, Youmin; Wu, Bo; Zhou, Kaibo; Ge, Mingfeng

    2015-03-01

    A novel adaptive sliding mode control algorithm is derived to deal with seam tracking control problem of welding robotic manipulator, during the process of large-scale structure component welding. The proposed algorithm does not require the precise dynamic model, and is more practical. Its robustness is verified by the Lyapunov stability theory. The analytical results show that the proposed algorithm enables better high-precision tracking performance with chattering-free than traditional sliding mode control algorithm under various disturbances.

  18. Adaptive sliding mode control for a class of chaotic systems

    SciTech Connect

    Farid, R.; Ibrahim, A.; Zalam, B.

    2015-03-30

    Chaos control here means to design a controller that is able to mitigating or eliminating the chaos behavior of nonlinear systems that experiencing such phenomenon. In this paper, an Adaptive Sliding Mode Controller (ASMC) is presented based on Lyapunov stability theory. The well known Chua's circuit is chosen to be our case study in this paper. The study shows the effectiveness of the proposed adaptive sliding mode controller.

  19. Sliding regimes on slow manifolds of systems with fast actuators

    NASA Technical Reports Server (NTRS)

    Sira-Ramirez, Hebertt; Dwyer, Thomas A. W., III

    1987-01-01

    In this article the slow manifold of a system with actuator parasitics is used as a sliding surface on which a Variable Structure Controller recovers the qualitative properties of the reduced order, closed loop system obtained from an ideal actuator-based feedback controller design. Illustrative examples are presented, where (1) the simplicity of reduced order singular perturbation design methods; and (2) the robustness of Variable Structure sliding modes, are advantageously combined.

  20. The slide centrifuge gram stain as a urine screening method.

    PubMed

    Olson, M L; Shanholtzer, C J; Willard, K E; Peterson, L R

    1991-10-01

    A slide centrifuge Gram stain procedure was performed to screen for bacteriuria 4161 urine specimens submitted in urine preservative tubes for routine culture. For slide centrifuge Gram staining, each urine sample was mixed well. Thereafter, 0.2 mL of each sample was placed, using a pipette, into a slide centrifuge chamber and centrifuged at 2,000 rpm for 5 minutes. The slides were heat fixed, Gram stained, and read by laboratory personnel who scanned 12 consecutive oil-immersion fields using a set pattern. The presence of the same organism in six or more fields was defined as a positive urine screen. Urine samples were cultured using a 0.001-mL loop and a comparison of culture growth with slide centrifuge screening was made. When growth of 100,000 or more colony-forming units per milliliter (CFU/mL) was the reference for comparison, the screen had a sensitivity rate of 98%, a specificity rate of 90%, a negative predictive value of 99%, and a positive predictive value of 65%. When a lower colony count of 10,000 or more CFU/mL was the reference for comparison, the screen had a sensitivity rate of 88%, a specificity rate of 95%, a negative predictive value of 96%, and a positive predictive value of 84%. The slide centrifuge Gram stain is a very sensitive screening method to detect bacteriuria in an adult male population.