Sample records for share common values

  1. 77 FR 75207 - The Adams Express Company and Petroleum & Resources Corporation; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... the Fund's long-term total return (in relation to market price and net asset value per common share... fixed percentage of the market price of such Fund's common shares at a particular point in time, or a..., dealer, bank or other person (``financial intermediary'') holds common shares issued by a Fund in nominee...

  2. 76 FR 59458 - Stone Harbor Emerging Markets Income Fund, et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... market price and its net asset value per common share (``NAV'')) and the relationship between such Fund's... the market price of such Fund's common shares at a particular point in time or a fixed monthly... person (``financial intermediary'') holds common shares issued by the Fund in nominee name, or otherwise...

  3. 26 CFR 25.2512-6 - Valuation of certain life insurance and annuity contracts; valuation of shares in an open-end...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) The fair market value of a share in an open-end investment company (commonly known as a “mutual fund... is a Saturday, Sunday, or holiday), the fair market value of the mutual fund share is the last public...

  4. 26 CFR 20.2031-8 - Valuation of certain life insurance and annuity contracts; valuation of shares in an open-end...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) The fair market value of a share in an open-end investment company (commonly known as a “mutual fund..., or holiday), the fair market value of the mutual fund share is the last public redemption price...

  5. 75 FR 57310 - American Capital, Ltd.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... markets for the common stock, the Fair Market Value will be determined in good faith by the Board, but in.... Under the Plan, a maximum of 750,000 shares of applicant's common stock, in the aggregate, may be issued to Non-employee Directors and options to purchase 93,750 shares of applicant's common stock may be...

  6. Revitalizing communities together: the shared values, goals, and work of education, urban planning, and public health.

    PubMed

    Cohen, Alison Klebanoff; Schuchter, Joseph W

    2013-04-01

    Inequities in education, the urban environment, and health co-exist and mutually reinforce each other. Educators, planners, and public health practitioners share commitments to place-based, participatory, youth-focused, and equitable work. They also have shared goals of building community resilience, social capital, and civic engagement. Interdisciplinary programs that embody these shared values and work towards these shared goals are emerging, including school-based health centers, full-service community schools, community health centers, Promise Neighborhoods, and Choice Neighborhoods. The intersection of these three fields represents an opportunity to intervene on social determinants of health. More collaborative research and practice across public health, education, and planning should build from the shared values identified to continue to address these common goals.

  7. A Case Study in Organizational Culture: Administrator's Shared Values, Perceptions, and Beliefs.

    ERIC Educational Resources Information Center

    Papalewis, Rosemary

    1988-01-01

    This case study aims to identify the organizational culture of an effective California school district's management style as experienced by its administrators. Questions addressed shared values, common perceptions, and beliefs. Data showed that a strong culture based on cooperative competition exists among district administrators. Includes the…

  8. Value-based cost sharing in the United States and elsewhere can increase patients' use of high-value goods and services.

    PubMed

    Thomson, Sarah; Schang, Laura; Chernew, Michael E

    2013-04-01

    This article reviews efforts in the United States and several other member countries of the Organization for Economic Cooperation and Development to encourage patients, through cost sharing, to use goods such as medications, services, and providers that offer better value than other options--an approach known as value-based cost sharing. Among the countries we reviewed, we found that value-based approaches were most commonly applied to drug cost sharing. A few countries, including the United States, employed financial incentives, such as lower copayments, to encourage use of preferred providers or preventive services. Evidence suggests that these efforts can increase patients' use of high-value services--although they may also be associated with high administrative costs and could exacerbate health inequalities among various groups. With careful design, implementation, and evaluation, value-based cost sharing can be an important tool for aligning patient and provider incentives to pursue high-value care.

  9. The Evolution of the Shared Services Business Unit.

    ERIC Educational Resources Information Center

    Forst, Leland

    2000-01-01

    Explains shared services, where common business practices are applied by a staff unit focused entirely on delivering needed services at the highest value and lowest cost to internal customers. Highlights include accountability; examples of pioneering shared services organizations; customer focus transition; relationship management; expertise…

  10. The Collaborative Capacity of the NYPD, FDNY, and EMS in New York City: A Focus on the First Line Officer

    DTIC Science & Technology

    2010-03-01

    of shared assumptions. Each respective agency has rituals and celebrations that reinforce traditions within an individualistic culture . The...to consider ways of enhancing members’ sense of shared values. Developing a more collectivistic culture , one that emphasizes the value of common...environment and to meet the challenges with all the homeland security partners. Different types of trust and influences of organizational cultures

  11. Analysis of shared heritability in common disorders of the brain.

    PubMed

    Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K; Walters, Raymond K; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina; Falcone, Guido J; Gormley, Padhraig; Malik, Rainer; Patsopoulos, Nikolaos A; Ripke, Stephan; Wei, Zhi; Yu, Dongmei; Lee, Phil H; Turley, Patrick; Grenier-Boley, Benjamin; Chouraki, Vincent; Kamatani, Yoichiro; Berr, Claudine; Letenneur, Luc; Hannequin, Didier; Amouyel, Philippe; Boland, Anne; Deleuze, Jean-François; Duron, Emmanuelle; Vardarajan, Badri N; Reitz, Christiane; Goate, Alison M; Huentelman, Matthew J; Kamboh, M Ilyas; Larson, Eric B; Rogaeva, Ekaterina; St George-Hyslop, Peter; Hakonarson, Hakon; Kukull, Walter A; Farrer, Lindsay A; Barnes, Lisa L; Beach, Thomas G; Demirci, F Yesim; Head, Elizabeth; Hulette, Christine M; Jicha, Gregory A; Kauwe, John S K; Kaye, Jeffrey A; Leverenz, James B; Levey, Allan I; Lieberman, Andrew P; Pankratz, Vernon S; Poon, Wayne W; Quinn, Joseph F; Saykin, Andrew J; Schneider, Lon S; Smith, Amanda G; Sonnen, Joshua A; Stern, Robert A; Van Deerlin, Vivianna M; Van Eldik, Linda J; Harold, Denise; Russo, Giancarlo; Rubinsztein, David C; Bayer, Anthony; Tsolaki, Magda; Proitsi, Petra; Fox, Nick C; Hampel, Harald; Owen, Michael J; Mead, Simon; Passmore, Peter; Morgan, Kevin; Nöthen, Markus M; Rossor, Martin; Lupton, Michelle K; Hoffmann, Per; Kornhuber, Johannes; Lawlor, Brian; McQuillin, Andrew; Al-Chalabi, Ammar; Bis, Joshua C; Ruiz, Agustin; Boada, Mercè; Seshadri, Sudha; Beiser, Alexa; Rice, Kenneth; van der Lee, Sven J; De Jager, Philip L; Geschwind, Daniel H; Riemenschneider, Matthias; Riedel-Heller, Steffi; Rotter, Jerome I; Ransmayr, Gerhard; Hyman, Bradley T; Cruchaga, Carlos; Alegret, Montserrat; Winsvold, Bendik; Palta, Priit; Farh, Kai-How; Cuenca-Leon, Ester; Furlotte, Nicholas; Kurth, Tobias; Ligthart, Lannie; Terwindt, Gisela M; Freilinger, Tobias; Ran, Caroline; Gordon, Scott D; Borck, Guntram; Adams, Hieab H H; Lehtimäki, Terho; Wedenoja, Juho; Buring, Julie E; Schürks, Markus; Hrafnsdottir, Maria; Hottenga, Jouke-Jan; Penninx, Brenda; Artto, Ville; Kaunisto, Mari; Vepsäläinen, Salli; Martin, Nicholas G; Montgomery, Grant W; Kurki, Mitja I; Hämäläinen, Eija; Huang, Hailiang; Huang, Jie; Sandor, Cynthia; Webber, Caleb; Muller-Myhsok, Bertram; Schreiber, Stefan; Salomaa, Veikko; Loehrer, Elizabeth; Göbel, Hartmut; Macaya, Alfons; Pozo-Rosich, Patricia; Hansen, Thomas; Werge, Thomas; Kaprio, Jaakko; Metspalu, Andres; Kubisch, Christian; Ferrari, Michel D; Belin, Andrea C; van den Maagdenberg, Arn M J M; Zwart, John-Anker; Boomsma, Dorret; Eriksson, Nicholas; Olesen, Jes; Chasman, Daniel I; Nyholt, Dale R; Avbersek, Andreja; Baum, Larry; Berkovic, Samuel; Bradfield, Jonathan; Buono, Russell; Catarino, Claudia B; Cossette, Patrick; De Jonghe, Peter; Depondt, Chantal; Dlugos, Dennis; Ferraro, Thomas N; French, Jacqueline; Hjalgrim, Helle; Jamnadas-Khoda, Jennifer; Kälviäinen, Reetta; Kunz, Wolfram S; Lerche, Holger; Leu, Costin; Lindhout, Dick; Lo, Warren; Lowenstein, Daniel; McCormack, Mark; Møller, Rikke S; Molloy, Anne; Ng, Ping-Wing; Oliver, Karen; Privitera, Michael; Radtke, Rodney; Ruppert, Ann-Kathrin; Sander, Thomas; Schachter, Steven; Schankin, Christoph; Scheffer, Ingrid; Schoch, Susanne; Sisodiya, Sanjay M; Smith, Philip; Sperling, Michael; Striano, Pasquale; Surges, Rainer; Thomas, G Neil; Visscher, Frank; Whelan, Christopher D; Zara, Federico; Heinzen, Erin L; Marson, Anthony; Becker, Felicitas; Stroink, Hans; Zimprich, Fritz; Gasser, Thomas; Gibbs, Raphael; Heutink, Peter; Martinez, Maria; Morris, Huw R; Sharma, Manu; Ryten, Mina; Mok, Kin Y; Pulit, Sara; Bevan, Steve; Holliday, Elizabeth; Attia, John; Battey, Thomas; Boncoraglio, Giorgio; Thijs, Vincent; Chen, Wei-Min; Mitchell, Braxton; Rothwell, Peter; Sharma, Pankaj; Sudlow, Cathie; Vicente, Astrid; Markus, Hugh; Kourkoulis, Christina; Pera, Joana; Raffeld, Miriam; Silliman, Scott; Boraska Perica, Vesna; Thornton, Laura M; Huckins, Laura M; William Rayner, N; Lewis, Cathryn M; Gratacos, Monica; Rybakowski, Filip; Keski-Rahkonen, Anna; Raevuori, Anu; Hudson, James I; Reichborn-Kjennerud, Ted; Monteleone, Palmiero; Karwautz, Andreas; Mannik, Katrin; Baker, Jessica H; O'Toole, Julie K; Trace, Sara E; Davis, Oliver S P; Helder, Sietske G; Ehrlich, Stefan; Herpertz-Dahlmann, Beate; Danner, Unna N; van Elburg, Annemarie A; Clementi, Maurizio; Forzan, Monica; Docampo, Elisa; Lissowska, Jolanta; Hauser, Joanna; Tortorella, Alfonso; Maj, Mario; Gonidakis, Fragiskos; Tziouvas, Konstantinos; Papezova, Hana; Yilmaz, Zeynep; Wagner, Gudrun; Cohen-Woods, Sarah; Herms, Stefan; Julià, Antonio; Rabionet, Raquel; Dick, Danielle M; Ripatti, Samuli; Andreassen, Ole A; Espeseth, Thomas; Lundervold, Astri J; Steen, Vidar M; Pinto, Dalila; Scherer, Stephen W; Aschauer, Harald; Schosser, Alexandra; Alfredsson, Lars; Padyukov, Leonid; Halmi, Katherine A; Mitchell, James; Strober, Michael; Bergen, Andrew W; Kaye, Walter; Szatkiewicz, Jin Peng; Cormand, Bru; Ramos-Quiroga, Josep Antoni; Sánchez-Mora, Cristina; Ribasés, Marta; Casas, Miguel; Hervas, Amaia; Arranz, Maria Jesús; Haavik, Jan; Zayats, Tetyana; Johansson, Stefan; Williams, Nigel; Dempfle, Astrid; Rothenberger, Aribert; Kuntsi, Jonna; Oades, Robert D; Banaschewski, Tobias; Franke, Barbara; Buitelaar, Jan K; Arias Vasquez, Alejandro; Doyle, Alysa E; Reif, Andreas; Lesch, Klaus-Peter; Freitag, Christine; Rivero, Olga; Palmason, Haukur; Romanos, Marcel; Langley, Kate; Rietschel, Marcella; Witt, Stephanie H; Dalsgaard, Soeren; Børglum, Anders D; Waldman, Irwin; Wilmot, Beth; Molly, Nikolas; Bau, Claiton H D; Crosbie, Jennifer; Schachar, Russell; Loo, Sandra K; McGough, James J; Grevet, Eugenio H; Medland, Sarah E; Robinson, Elise; Weiss, Lauren A; Bacchelli, Elena; Bailey, Anthony; Bal, Vanessa; Battaglia, Agatino; Betancur, Catalina; Bolton, Patrick; Cantor, Rita; Celestino-Soper, Patrícia; Dawson, Geraldine; De Rubeis, Silvia; Duque, Frederico; Green, Andrew; Klauck, Sabine M; Leboyer, Marion; Levitt, Pat; Maestrini, Elena; Mane, Shrikant; De-Luca, Daniel Moreno-; Parr, Jeremy; Regan, Regina; Reichenberg, Abraham; Sandin, Sven; Vorstman, Jacob; Wassink, Thomas; Wijsman, Ellen; Cook, Edwin; Santangelo, Susan; Delorme, Richard; Rogé, Bernadette; Magalhaes, Tiago; Arking, Dan; Schulze, Thomas G; Thompson, Robert C; Strohmaier, Jana; Matthews, Keith; Melle, Ingrid; Morris, Derek; Blackwood, Douglas; McIntosh, Andrew; Bergen, Sarah E; Schalling, Martin; Jamain, Stéphane; Maaser, Anna; Fischer, Sascha B; Reinbold, Céline S; Fullerton, Janice M; Guzman-Parra, José; Mayoral, Fermin; Schofield, Peter R; Cichon, Sven; Mühleisen, Thomas W; Degenhardt, Franziska; Schumacher, Johannes; Bauer, Michael; Mitchell, Philip B; Gershon, Elliot S; Rice, John; Potash, James B; Zandi, Peter P; Craddock, Nick; Ferrier, I Nicol; Alda, Martin; Rouleau, Guy A; Turecki, Gustavo; Ophoff, Roel; Pato, Carlos; Anjorin, Adebayo; Stahl, Eli; Leber, Markus; Czerski, Piotr M; Cruceanu, Cristiana; Jones, Ian R; Posthuma, Danielle; Andlauer, Till F M; Forstner, Andreas J; Streit, Fabian; Baune, Bernhard T; Air, Tracy; Sinnamon, Grant; Wray, Naomi R; MacIntyre, Donald J; Porteous, David; Homuth, Georg; Rivera, Margarita; Grove, Jakob; Middeldorp, Christel M; Hickie, Ian; Pergadia, Michele; Mehta, Divya; Smit, Johannes H; Jansen, Rick; de Geus, Eco; Dunn, Erin; Li, Qingqin S; Nauck, Matthias; Schoevers, Robert A; Beekman, Aartjan Tf; Knowles, James A; Viktorin, Alexander; Arnold, Paul; Barr, Cathy L; Bedoya-Berrio, Gabriel; Bienvenu, O Joseph; Brentani, Helena; Burton, Christie; Camarena, Beatriz; Cappi, Carolina; Cath, Danielle; Cavallini, Maria; Cusi, Daniele; Darrow, Sabrina; Denys, Damiaan; Derks, Eske M; Dietrich, Andrea; Fernandez, Thomas; Figee, Martijn; Freimer, Nelson; Gerber, Gloria; Grados, Marco; Greenberg, Erica; Hanna, Gregory L; Hartmann, Andreas; Hirschtritt, Matthew E; Hoekstra, Pieter J; Huang, Alden; Huyser, Chaim; Illmann, Cornelia; Jenike, Michael; Kuperman, Samuel; Leventhal, Bennett; Lochner, Christine; Lyon, Gholson J; Macciardi, Fabio; Madruga-Garrido, Marcos; Malaty, Irene A; Maras, Athanasios; McGrath, Lauren; Miguel, Eurípedes C; Mir, Pablo; Nestadt, Gerald; Nicolini, Humberto; Okun, Michael S; Pakstis, Andrew; Paschou, Peristera; Piacentini, John; Pittenger, Christopher; Plessen, Kerstin; Ramensky, Vasily; Ramos, Eliana M; Reus, Victor; Richter, Margaret A; Riddle, Mark A; Robertson, Mary M; Roessner, Veit; Rosário, Maria; Samuels, Jack F; Sandor, Paul; Stein, Dan J; Tsetsos, Fotis; Van Nieuwerburgh, Filip; Weatherall, Sarah; Wendland, Jens R; Wolanczyk, Tomasz; Worbe, Yulia; Zai, Gwyneth; Goes, Fernando S; McLaughlin, Nicole; Nestadt, Paul S; Grabe, Hans-Jorgen; Depienne, Christel; Konkashbaev, Anuar; Lanzagorta, Nuria; Valencia-Duarte, Ana; Bramon, Elvira; Buccola, Nancy; Cahn, Wiepke; Cairns, Murray; Chong, Siow A; Cohen, David; Crespo-Facorro, Benedicto; Crowley, James; Davidson, Michael; DeLisi, Lynn; Dinan, Timothy; Donohoe, Gary; Drapeau, Elodie; Duan, Jubao; Haan, Lieuwe; Hougaard, David; Karachanak-Yankova, Sena; Khrunin, Andrey; Klovins, Janis; Kučinskas, Vaidutis; Lee Chee Keong, Jimmy; Limborska, Svetlana; Loughland, Carmel; Lönnqvist, Jouko; Maher, Brion; Mattheisen, Manuel; McDonald, Colm; Murphy, Kieran C; Nenadic, Igor; van Os, Jim; Pantelis, Christos; Pato, Michele; Petryshen, Tracey; Quested, Digby; Roussos, Panos; Sanders, Alan R; Schall, Ulrich; Schwab, Sibylle G; Sim, Kang; So, Hon-Cheong; Stögmann, Elisabeth; Subramaniam, Mythily; Toncheva, Draga; Waddington, John; Walters, James; Weiser, Mark; Cheng, Wei; Cloninger, Robert; Curtis, David; Gejman, Pablo V; Henskens, Frans; Mattingsdal, Morten; Oh, Sang-Yun; Scott, Rodney; Webb, Bradley; Breen, Gerome; Churchhouse, Claire; Bulik, Cynthia M; Daly, Mark; Dichgans, Martin; Faraone, Stephen V; Guerreiro, Rita; Holmans, Peter; Kendler, Kenneth S; Koeleman, Bobby; Mathews, Carol A; Price, Alkes; Scharf, Jeremiah; Sklar, Pamela; Williams, Julie; Wood, Nicholas W; Cotsapas, Chris; Palotie, Aarno; Smoller, Jordan W; Sullivan, Patrick; Rosand, Jonathan; Corvin, Aiden; Neale, Benjamin M

    2018-06-22

    Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common variant risk, whereas neurological disorders appear more distinct from one another and from the psychiatric disorders. We also identified significant sharing between disorders and a number of brain phenotypes, including cognitive measures. Further, we conducted simulations to explore how statistical power, diagnostic misclassification, and phenotypic heterogeneity affect genetic correlations. These results highlight the importance of common genetic variation as a risk factor for brain disorders and the value of heritability-based methods in understanding their etiology. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  12. Finding Common Ground Between Earth Scientists and Evangelical Christians

    NASA Astrophysics Data System (ADS)

    Grant Ludwig, L.

    2015-12-01

    In recent decades there has been some tension between earth scientists and evangelical Christians in the U.S., and this tension has spilled over into the political arena and policymaking on important issues such as climate change. From my personal and professional experience engaging with both groups, I find there is much common ground for increasing understanding and communicating the societal relevance of earth science. Fruitful discussions can arise from shared values and principles, and common approaches to understanding the world. For example, scientists and Christians are engaged in the pursuit of truth, and they value moral/ethical decision-making based on established principles. Scientists emphasize the benefits of research "for the common good" while Christians emphasize the value of doing "good works". Both groups maintain a longterm perspective: Christians talk about "the eternal" and geologists discuss "deep time". Both groups understand the importance of placing new observations in context of prior understanding: scientists diligently reference "the literature" while Christians quote "chapter and verse". And members of each group engage with each other in "fellowship" or "meetings" to create a sense of community and reinforce shared values. From my perspective, earth scientists can learn to communicate the importance and relevance of science more effectively by engaging with Christians in areas of common ground, rather than by trying to win arguments or debates.

  13. Family Relational Values in the Parent-Adolescent Relationship

    ERIC Educational Resources Information Center

    Edgar-Smith, Susan E.; Wozniak, Robert H.

    2010-01-01

    This study measured the relational family values system of upper-middle-class mothers, fathers, and adolescents in the United States. Results revealed that participants shared common family values that mainly reflected the importance of individualism, equality in family relationships, family member interdependence, and parental guidance. Parent…

  14. Shared leadership in a newly merged medical center.

    PubMed

    Coluccio, M; Havlick, K

    1998-01-01

    Mergers of new health care entities require visionary leadership in forming effective partnerships. Shared leadership was one key ingredient in blending two major health care competitors in the Northwest. Building a successful foundation for shared leadership required formation of a common vision, definition of core values, and establishment of guiding principles. Honoring respective cultures, recognizing achievements, and inviting participation led to the design of the shared leadership model focused on the primary objective for the merger: Enhancing health care services to the community.

  15. 76 FR 52363 - Tortoise Power and Energy Infrastructure Fund, Inc. and Tortoise Capital Advisors, L.L.C.; Notice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ... relation to market price and net asset value (``NAV'') per common share) and the relationship between the... relation to NAV per share). Applicants state that the Independent Directors also considered what conflicts... appropriate in the public interest and consistent with the protection of investors and the purposes fairly...

  16. 78 FR 18451 - Education and Sharing Day, U.S.A., 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-26

    ... must we pass on the common values that help define us as a people. On Education and Sharing Day, U.S.A... our youth. We know education is essential to putting our children on the path to good jobs and a... men and women the importance of education and good character. His work strengthened ties between...

  17. A neural model of valuation and information virality

    PubMed Central

    Baek, Elisa C.; O’Donnell, Matthew Brook; Kim, Hyun Suk; Cappella, Joseph N.

    2017-01-01

    Information sharing is an integral part of human interaction that serves to build social relationships and affects attitudes and behaviors in individuals and large groups. We present a unifying neurocognitive framework of mechanisms underlying information sharing at scale (virality). We argue that expectations regarding self-related and social consequences of sharing (e.g., in the form of potential for self-enhancement or social approval) are integrated into a domain-general value signal that encodes the value of sharing a piece of information. This value signal translates into population-level virality. In two studies (n = 41 and 39 participants), we tested these hypotheses using functional neuroimaging. Neural activity in response to 80 New York Times articles was observed in theory-driven regions of interest associated with value, self, and social cognitions. This activity then was linked to objectively logged population-level data encompassing n = 117,611 internet shares of the articles. In both studies, activity in neural regions associated with self-related and social cognition was indirectly related to population-level sharing through increased neural activation in the brain's value system. Neural activity further predicted population-level outcomes over and above the variance explained by article characteristics and commonly used self-report measures of sharing intentions. This parsimonious framework may help advance theory, improve predictive models, and inform new approaches to effective intervention. More broadly, these data shed light on the core functions of sharing—to express ourselves in positive ways and to strengthen our social bonds. PMID:28242678

  18. Institute on Human Values in Medicine. Human Values Teaching Programs for Health Professionals.

    ERIC Educational Resources Information Center

    Society for Health and Human Values, Philadelphia, PA.

    This document contains descriptions of 19 teaching programs which share the common goal of emphasizing human values as an important area of education in the health professions. This listing is the result and expansion of the Institute on Health and Human Values Conference. Three broad areas are outlined which the 19 schools emphasize in their…

  19. Behavioral Considerations for Space Station Design.

    DTIC Science & Technology

    1986-01-01

    example, provide individuals an opportunity for shared experiences, common values and shared outlooks ( Durkheim , 1964; Homans, 1974). Different roles...efforts are required to achieve the desired goals ( Durkheim , 1964; Goffman, 1961). Conversely, role specification may impede cohesion if the roles are...as a function of office space and physiognomy: Two studies of influence. Psychological Reports, 40, 758-760. Durkheim , E. (1964). The division of

  20. Incentive mechanism based on cooperative advertising for cost information sharing in a supply chain with competing retailers

    NASA Astrophysics Data System (ADS)

    Setak, Mostafa; Kafshian Ahar, Hajar; Alaei, Saeed

    2017-09-01

    This paper proposes a new motivation for information sharing in a decentralized channel consisting of a single manufacturer and two competing retailers. The manufacturer provides a common product to the retailers at the same wholesale price. Both retailers add their own values to the product and distribute it to consumers. Factors such as retail prices, values added to the product, and local advertising of the retailers simultaneously have effect on market demand. Each retailer has full information about the own added value which is unknown to the manufacturer and other retailer. The manufacturer uses a cooperative advertising program for motivating the retailers to disclose their private information. A numerical study is presented to compare different scenarios of information sharing. Computational results show that there is a condition in which full information sharing is beneficial for all members of the supply chain through cooperative advertising program and, therefore, retailers have enough incentive to disclose their cost information to the manufacturer.

  1. Grandparents, Grandchildren, and the Kondratieff: Thoughts on "Period Effects" in Intergenerational Analyses.

    ERIC Educational Resources Information Center

    Kearl, Michael C.; Hermes, Michael P.

    1984-01-01

    Discusses the socialization of values from a sociohistorical perspective. Argues that value similarities between grandparents and grandchildren are a result of skipped generations being socialized within similar phases of the Kondratieff Wave. Consequently, they bear analogous historical imprints and share common outlooks. Includes a review by…

  2. Is There a Difference in Learning Style among Cultures?

    ERIC Educational Resources Information Center

    Fierro, Darlene

    Each child has a personal learning style that results from innate tendencies and environmental experiences. Because cultural groups often share common values, the experiences of children growing up with those values are reflected in their classroom learning behaviors. This paper discusses cultural differences in children's learning styles. The…

  3. Ethical concerns: comparison of values from two cultures.

    PubMed

    Wros, Peggy L; Doutrich, Dawn; Izumi, Shigeko

    2004-06-01

    The present study was a secondary analysis of data from two phenomenological studies of nurses in the USA and Japan. The study incorporated hermeneutics and feminist methodologies to answer the following questions. Are there common values and ethical concerns and values within the nursing cultures of Japan and the USA? What are some commonalities and differences between Japanese nurses' ethical concerns and those of American nurses? Findings indicated that nurses from the USA and Japan share common values and ethical concerns as professional nurses, including competence, respect for the patient as a person, responsibility, relationship and connection, importance of the family, caring, good death, comfort, truth-telling, understanding the patient/situation, and anticipatory care. Although ethical concerns are similar, related background meanings and actions often look different between cultures; truth-telling is described as an example. Nurses in each country also hold unique values not found in the nursing practice of the other country. Understanding these commonalities and differences is critical for the development of global nursing ethics.

  4. The value of Autoimmune Syndrome Induced by Adjuvant (ASIA) - Shedding light on orphan diseases in autoimmunity.

    PubMed

    Segal, Yahel; Dahan, Shani; Sharif, Kassem; Bragazzi, Nicola Luigi; Watad, Abdulla; Amital, Howard

    2018-05-01

    Autoimmune Syndrome Induced by Adjuvant (ASIA) is a definition aimed to describe the common etiological process at the root of five clinical entities sharing similar symptomatology: macrophagic myofasciitis syndrome (MMF), Gulf War Syndrome (GWS), sick building syndrome (SBS), siliconosis, and post vaccination autoimmune phenomena. ASIA illustrates the role of environmental immune stimulating agents, or adjuvants, in the instigation of complex autoimmune reactions among individuals bearing a genetic preponderance for autoimmunity. The value of ASIA lies first in the acknowledgment it provides for patients suffering from these as yet ill-defined medical conditions. Equally important is the spotlight it sheds for further research of these poorly understood conditions sharing a common pathogenesis. In this article we elaborate on the significance of ASIA, review the current evidence in support of the syndrome, and address recent reservations raised regarding its validity. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. 26 CFR 1.1563-1 - Definition of controlled group of corporations and component members and related concepts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... possessing 80 percent of the total value of shares of all classes of stock of X Corporation. P is the common... the voting power or value of at least one of the other corporations, P is treated as the owner of... section. (P and Y together own stock possessing 100 percent of the voting power and value of Z, and P and...

  6. Toward Developing a Universal Code of Ethics for Adult Educators.

    ERIC Educational Resources Information Center

    Siegel, Irwin H.

    2000-01-01

    Presents conflicting viewpoints on a universal code of ethics for adult educators. Suggests objectives of a code (guidance for practice, policymaking direction, common reference point, shared values). Outlines content and methods for implementing a code. (SK)

  7. An Analysis of the Educational Value of Low-Fidelity Anatomy Models as External Representations

    ERIC Educational Resources Information Center

    Chan, Lap Ki; Cheng, Maurice M. W.

    2011-01-01

    Although high-fidelity digital models of human anatomy based on actual cross-sectional images of the human body have been developed, reports on the use of physical models in anatomy teaching continue to appear. This article aims to examine the common features shared by these physical models and analyze their educational value based on the…

  8. The Value of Community Building: One Center's Story of How the VALUE Rubrics Provided Common Ground

    ERIC Educational Resources Information Center

    Jardeleza, Sarah; Cognato, April; Gottfried, Michael; Kimbirauskas, Ryan; Libarkin, Julie; Olson, Rachel; Ording, Gabriel; Owen, Jennifer; Rasmussen, Pamela; Stoltzfus, Jon; Thomas, Stephen

    2013-01-01

    Although their structures and funding sources differ, Research I institutions and small liberal arts colleges share the same goal of helping students master the knowledge and skills that will enable them to become informed citizens who are able to contribute effectively a democratic society. But how can this transformation be achieved, and what…

  9. The Effects of Shared Information on Pilot-Controller Situation Awareness And Re-Route Negotiation

    NASA Technical Reports Server (NTRS)

    Farley, Todd C.; Hansman, R. John; Endsley, Mica R.; Amonlirdviman, Keith

    1999-01-01

    The effect of shared information is assessed in terms of pilot-controller negotiating behavior and shared situation awareness. Pilot goals and situation awareness requirements are developed and compared against those of air traffic controllers to identify areas of common and competing interest. An exploratory, part-task simulator experiment is described which evaluates the extent to which shared information may lead pilots and controllers to cooperate or compete when negotiating route amendments. Results are presented which indicate that shared information enhances situation awareness and can engender more collaborative interaction between pilots and air traffic controllers. Furthermore, the value of providing controllers with a good-quality weather overlay on their plan view displays is demonstrated. Observed improvements in situation awareness and separation assurance are discussed.

  10. Cross-disease Meta-analysis of Genome-wide Association Studies for Systemic Sclerosis and Rheumatoid Arthritis Reveals IRF4 as a New Common Susceptibility Locus

    PubMed Central

    López-Isac, Elena; Martín, Jose-Ezequiel; Assassi, Shervin; Simeón, Carmen P; Carreira, Patricia; Ortego-Centeno, Norberto; Freire, Mayka; Beltrán, Emma; Narváez, Javier; Alegre-Sancho, Juan J; Fernández-Gutiérrez, Benjamín; Balsa, Alejandro; Ortiz, Ana M; González-Gay, Miguel A; Beretta, Lorenzo; Santaniello, Alessandro; Bellocchi, Chiara; Lunardi, Claudio; Moroncini, Gianluca; Gabrielli, Armando; Witte, Torsten; Hunzelmann, Nicolas; Distler, Jörg HW; Riekemasten, Gabriella; van der Helm-van Mil, Annete H; de Vries-Bouwstra, Jeska; Magro-Checa, Cesar; Voskuyl, Alexandre E; Vonk, Madelon C; Molberg, Øyvind; Merriman, Tony; Hesselstrand, Roger; Nordin, Annika; Padyukov, Leonid; Herrick, Ariane; Eyre, Steve; Koeleman, Bobby PC; Denton, Christopher P; Fonseca, Carmen; Radstake, Timothy RDJ; Worthington, Jane; Mayes, Maureen D; Martín, Javier

    2017-01-01

    Objectives Systemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases that share clinical and immunological characteristics. To date, several shared SSc-RA loci have been identified independently. In this study, we aimed to systematically search for new common SSc-RA loci through an inter-disease meta-GWAS strategy. Methods We performed a meta-analysis combining GWAS datasets of SSc and RA using a strategy that allowed identification of loci with both same-direction and opposing-direction allelic effects. The top single-nucleotide polymorphisms (SNPs) were followed-up in independent SSc and RA case-control cohorts. This allowed us to increase the sample size to a total of 8,830 SSc patients, 16,870 RA patients and 43,393 controls. Results The cross-disease meta-analysis of the GWAS datasets identified several loci with nominal association signals (P-value < 5 × 10-6), which also showed evidence of association in the disease-specific GWAS scan. These loci included several genomic regions not previously reported as shared loci, besides risk factors associated with both diseases in previous studies. The follow-up of the putatively new SSc-RA loci identified IRF4 as a shared risk factor for these two diseases (Pcombined = 3.29 × 10-12). In addition, the analysis of the biological relevance of the known SSc-RA shared loci pointed to the type I interferon and the interleukin 12 signaling pathways as the main common etiopathogenic factors. Conclusions Our study has identified a novel shared locus, IRF4, for SSc and RA and highlighted the usefulness of cross-disease GWAS meta-analysis in the identification of common risk loci. PMID:27111665

  11. Identifying common values among seven health professions: An interprofessional analysis.

    PubMed

    Grace, Sandra; Innes, Ev; Joffe, Beverly; East, Leah; Coutts, Rosanne; Nancarrow, Susan

    2017-05-01

    This article reviews the competency frameworks of seven Australian health professions to explore relationships among health professions of similar status as reflected in their competency frameworks and to identify common themes and values across the professions. Frameworks were compared using a constructivist grounded theory approach to identify key themes, against which individual competencies for each profession were mapped and compared. The themes were examined for underlying values and a higher order theoretical framework was developed. In contrast to classical theories of professionalism that foreground differentiation of professions, our study suggests that the professions embrace a common structure and understanding, based on shared underpinning values. We propose a model of two core values that encompass all identified themes: the rights of the client and the capacity of a particular profession to serve the healthcare needs of clients. Interprofessional practice represents the intersection of the rights of the client to receive the best available healthcare and the recognition of the individual contribution of each profession. Recognising that all health professions adhere to a common value base, and exploring professional similarities and differences from that value base, challenges a paradigm that distinguishes professions solely on scope of practice.

  12. 3 CFR 8655 - Proclamation 8655 of April 14, 2011. Education and Sharing Day, U.S.A., 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... generations the values that will help them write the next proud chapter of the American story—a dedication to... extraordinary challenge and our dedication to our common humanity. We must nurture these traits in our children...

  13. Developing regionally specific grazing practices to promote production, profitability, and environmental quality

    USDA-ARS?s Scientific Manuscript database

    Rangelands are valued for their capacity to provide diverse suites of ecosystem services, from food production to carbon storage to biological diversity. Although rangelands worldwide share common characteristics, differences among biogeographic regions result in differences in the types of opportun...

  14. Are the core values of the radiological protection system shared across cultures?

    PubMed

    Zölzer, F

    2016-06-01

    In spite of ongoing globalisation in many fields, the ethics of radiological protection have long been discussed almost exclusively in terms of 'Western' moral philosophy concepts such as utilitarianism or deontology. A cross-cultural discourse in this field is only just beginning. In 'Principles of Biomedical Ethics', Beauchamp and Childress suggested that there exists a 'common morality' which is 'not relative to cultures or individuals, because it transcends both'. They proposed four cross-culturally valid principles for decision making in medicine: respect for autonomy, non-maleficence, beneficence, and justice. A similar approach is being developed by the International Commission on Radiological Protection Task Group 94 on the ethics of radiological protection. Here, the core values are: human dignity, beneficence/non-maleficence, prudence, and justice. Other values could be added, such as consideration for the interests of society as a whole or the interests of future generations, or procedural values such as transparency and accountability; this paper will include a brief discussion on how they relate to the four basic principles. The main question to be addressed here, however, is whether the proposed core values are indeed part of a 'common morality'. This, as it will be argued, cannot be decided by a global opinion poll, but has to be based on an analysis of the written and oral traditions that have provided ethical orientation throughout history, and are still considered seminal by the majority of people. It turns out that there are indeed many commonalities across cultures, and that the concept of globally shared core values for the radiological protection system is not hopelessly idealistic. © The International Society for Prosthetics and Orthotics.

  15. The I3I Model; Identifying Cultural Determinants of Information Sharing via C2 Information Technologies

    DTIC Science & Technology

    2009-06-01

    Individualist cultures represent loose ties between individuals where the interests of individuals prevail over the interests of the group and the...independence of individuals is emphasized. Individual accomplishments are valued whereas in collectivist cultures the group’s well being and common...goals and objectives are valued more. Collectivist cultures are characterized by tight social networks in which individuals strongly distinguish

  16. Share your sweets: Chimpanzee (Pan troglodytes) and bonobo (Pan paniscus) willingness to share highly attractive, monopolizable food sources.

    PubMed

    Byrnit, Jill T; Høgh-Olesen, Henrik; Makransky, Guido

    2015-08-01

    All over the world, humans (Homo sapiens) display resource-sharing behavior, and common patterns of sharing seem to exist across cultures. Humans are not the only primates to share, and observations from the wild have long documented food sharing behavior in our closest phylogenetic relatives, chimpanzees (Pan troglodytes) and bonobos (Pan paniscus). However, few controlled studies have been made in which groups of Pan are introduced to food items that may be shared or monopolized by a first food possessor, and very few studies have examined what happens to these sharing patterns if the food in question is a highly attractive, monopolizable food source. The one study to date to include food quality as the independent variable used different types of food as high- and low-value items, making differences in food divisibility and size potentially confounding factors. It was the aim of the present study to examine the sharing behavior of groups of captive chimpanzees and bonobos when introducing the same type of food (branches) manipulated to be of 2 different degrees of desirability (with or without syrup). Results showed that the large majority of food transfers in both species came about as sharing in which group members were allowed to cofeed or remove food from the stock of the food possessor, and the introduction of high-value food resulted in more sharing, not less. Food sharing behavior differed between species in that chimpanzees displayed significantly more begging behavior than bonobos. Bonobos, instead, engaged in sexual invitations, which the chimpanzees never did. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  17. Information Technology Wants to Be Free

    ERIC Educational Resources Information Center

    Poritz, Jonathan A.

    2012-01-01

    It makes sense for college and university faculty to ally with the free and open-source software community. They share common values. A marvelous additional benefit is that free software on campuses would significantly advance pedagogy and scholarship, increase efficiency, and save money. Only unquestioning obedience to market fundamentalism--or…

  18. An Analysis of Information Asset Valuation (IAV) Quantification Methodology for Application with Cyber Information Mission Impact Assessment (CIMIA)

    DTIC Science & Technology

    2008-03-01

    sponsor, Capt. Larry Fortson, for sharing a common vision; my knowledgeable committee members, Dr. Robert F. Mills and Dr. Dennis D. Strouble, for...Accounting Approaches ........................................................................ 16  vi Page Fair Market Value (FMV...22  Uniform Commercial Code ( UCC ) ....................................................................... 23

  19. Greek-Australians: A Question of Survival in Multicultural Australia.

    ERIC Educational Resources Information Center

    Smolicz, J. J.

    1985-01-01

    Argues that Australians from different ethnic backgrounds are not a threat to cohesion as long as they share the overarching values which are reflected in Australia's democracy, economic system, legal institutions, and in Engish as the common language of communication. Discusses the Greek-Australian tradition of family life. (SED)

  20. A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease

    PubMed Central

    Boucher, Gabrielle; Beauchamp, Claudine; Trynka, Gosia; Dubois, Patrick C.; Lagacé, Caroline; Stokkers, Pieter C. F.; Hommes, Daan W.; Barisani, Donatella; Palmieri, Orazio; Annese, Vito; van Heel, David A.; Weersma, Rinse K.; Daly, Mark J.; Wijmenga, Cisca; Rioux, John D.

    2011-01-01

    Crohn's disease (CD) and celiac disease (CelD) are chronic intestinal inflammatory diseases, involving genetic and environmental factors in their pathogenesis. The two diseases can co-occur within families, and studies suggest that CelD patients have a higher risk to develop CD than the general population. These observations suggest that CD and CelD may share common genetic risk loci. Two such shared loci, IL18RAP and PTPN2, have already been identified independently in these two diseases. The aim of our study was to explicitly identify shared risk loci for these diseases by combining results from genome-wide association study (GWAS) datasets of CD and CelD. Specifically, GWAS results from CelD (768 cases, 1,422 controls) and CD (3,230 cases, 4,829 controls) were combined in a meta-analysis. Nine independent regions had nominal association p-value <1.0×10−5 in this meta-analysis and showed evidence of association to the individual diseases in the original scans (p-value <1×10−2 in CelD and <1×10−3 in CD). These include the two previously reported shared loci, IL18RAP and PTPN2, with p-values of 3.37×10−8 and 6.39×10−9, respectively, in the meta-analysis. The other seven had not been reported as shared loci and thus were tested in additional CelD (3,149 cases and 4,714 controls) and CD (1,835 cases and 1,669 controls) cohorts. Two of these loci, TAGAP and PUS10, showed significant evidence of replication (Bonferroni corrected p-values <0.0071) in the combined CelD and CD replication cohorts and were firmly established as shared risk loci of genome-wide significance, with overall combined p-values of 1.55×10−10 and 1.38×10−11 respectively. Through a meta-analysis of GWAS data from CD and CelD, we have identified four shared risk loci: PTPN2, IL18RAP, TAGAP, and PUS10. The combined analysis of the two datasets provided the power, lacking in the individual GWAS for single diseases, to detect shared loci with a relatively small effect. PMID:21298027

  1. How learning one category influences the learning of another: intercategory generalization based on analogy and specific stimulus information.

    PubMed

    Nahinsky, Irwin D; Lucas, Barbara A; Edgell, Stephen E; Overfelt, Joseph; Loeb, Richard

    2004-01-01

    We investigated the effect of learning one category structure on the learning of a related category structure. Photograph-name combinations, called identifiers, were associated with values of four demographic attributes. Two problems were related by analogous demographic attributes, common identifiers, or both to examine the impact of common identifier, related general characteristics, and the interaction of the two variables in mediating learning transfer from one category structure to another. Problems sharing the same identifier information prompted greater positive transfer than those not sharing the same identifier information. In contrast, analogous defining characteristics in the two problems did not facilitate transfer. We computed correlations between responses to first-problem stimuli and responses to analogous second-problem stimuli for each participant. The analogous characteristics produced a tendency to respond in the same way to corresponding stimuli in the two problems. The results support an alignment between category structures related by analogous defining characteristics, which is facilitated by specific identifier information shared by two category structures.

  2. Coastal watershed management across an international border in the Tijuana River watershed

    NASA Astrophysics Data System (ADS)

    Fernandez, Linda

    2005-05-01

    The paper develops and applies a game theoretic model of upstream and downstream countries to examine cooperative and noncooperative strategies of a common watershed. The application to the Tijuana River watershed shared by the United States and Mexico provides quantification of the strategies for internalizing water quality externalities to upstream and downstream originating from sedimentation. Results show that different transfer payments, such as the Chander/Tulkens cost sharing rule and the Shapley value, imply the size of the existing transfer from downstream to upstream could increase the amount currently allocated.

  3. Visions of Restoration in Fire-Adapted Forest Landscapes: Lessons from the Collaborative Forest Landscape Restoration Program.

    PubMed

    Urgenson, Lauren S; Ryan, Clare M; Halpern, Charles B; Bakker, Jonathan D; Belote, R Travis; Franklin, Jerry F; Haugo, Ryan D; Nelson, Cara R; Waltz, Amy E M

    2017-02-01

    Collaborative approaches to natural resource management are becoming increasingly common on public lands. Negotiating a shared vision for desired conditions is a fundamental task of collaboration and serves as a foundation for developing management objectives and monitoring strategies. We explore the complex socio-ecological processes involved in developing a shared vision for collaborative restoration of fire-adapted forest landscapes. To understand participant perspectives and experiences, we analyzed interviews with 86 respondents from six collaboratives in the western U.S., part of the Collaborative Forest Landscape Restoration Program established to encourage collaborative, science-based restoration on U.S. Forest Service lands. Although forest landscapes and group characteristics vary considerably, collaboratives faced common challenges to developing a shared vision for desired conditions. Three broad categories of challenges emerged: meeting multiple objectives, collaborative capacity and trust, and integrating ecological science and social values in decision-making. Collaborative groups also used common strategies to address these challenges, including some that addressed multiple challenges. These included use of issue-based recommendations, field visits, and landscape-level analysis; obtaining support from local agency leadership, engaging facilitators, and working in smaller groups (sub-groups); and science engagement. Increased understanding of the challenges to, and strategies for, developing a shared vision of desired conditions is critical if other collaboratives are to learn from these efforts.

  4. Visions of Restoration in Fire-Adapted Forest Landscapes: Lessons from the Collaborative Forest Landscape Restoration Program

    NASA Astrophysics Data System (ADS)

    Urgenson, Lauren S.; Ryan, Clare M.; Halpern, Charles B.; Bakker, Jonathan D.; Belote, R. Travis; Franklin, Jerry F.; Haugo, Ryan D.; Nelson, Cara R.; Waltz, Amy E. M.

    2017-02-01

    Collaborative approaches to natural resource management are becoming increasingly common on public lands. Negotiating a shared vision for desired conditions is a fundamental task of collaboration and serves as a foundation for developing management objectives and monitoring strategies. We explore the complex socio-ecological processes involved in developing a shared vision for collaborative restoration of fire-adapted forest landscapes. To understand participant perspectives and experiences, we analyzed interviews with 86 respondents from six collaboratives in the western U.S., part of the Collaborative Forest Landscape Restoration Program established to encourage collaborative, science-based restoration on U.S. Forest Service lands. Although forest landscapes and group characteristics vary considerably, collaboratives faced common challenges to developing a shared vision for desired conditions. Three broad categories of challenges emerged: meeting multiple objectives, collaborative capacity and trust, and integrating ecological science and social values in decision-making. Collaborative groups also used common strategies to address these challenges, including some that addressed multiple challenges. These included use of issue-based recommendations, field visits, and landscape-level analysis; obtaining support from local agency leadership, engaging facilitators, and working in smaller groups (sub-groups); and science engagement. Increased understanding of the challenges to, and strategies for, developing a shared vision of desired conditions is critical if other collaboratives are to learn from these efforts.

  5. A Reconstruction Approach to High-Order Schemes Including Discontinuous Galerkin for Diffusion

    NASA Technical Reports Server (NTRS)

    Huynh, H. T.

    2009-01-01

    We introduce a new approach to high-order accuracy for the numerical solution of diffusion problems by solving the equations in differential form using a reconstruction technique. The approach has the advantages of simplicity and economy. It results in several new high-order methods including a simplified version of discontinuous Galerkin (DG). It also leads to new definitions of common value and common gradient quantities at each interface shared by the two adjacent cells. In addition, the new approach clarifies the relations among the various choices of new and existing common quantities. Fourier stability and accuracy analyses are carried out for the resulting schemes. Extensions to the case of quadrilateral meshes are obtained via tensor products. For the two-point boundary value problem (steady state), it is shown that these schemes, which include most popular DG methods, yield exact common interface quantities as well as exact cell average solutions for nearly all cases.

  6. Local knowledge: Empirical Fact to Develop Community Based Disaster Risk Management Concept for Community Resilience at Mangkang Kulon Village, Semarang City

    NASA Astrophysics Data System (ADS)

    Kapiarsa, A. B.; Sariffuddin, S.

    2018-02-01

    Local knowledge in disaster management should not be neglected in developing community resilience. The circular relation between humans and their living habitat and community social relation have developed the local knowledge namely specialized knowledge, shared knowledge, and common knowledge. Its correlation with community-based disaster management has become an important discussion specially to answer can local knowledge underlie community-based disaster risk reduction concept development? To answer this question, this research used mix-method. Interview and crosstab method for 73 respondents with 90% trust rate were used to determine the correlation between local knowledge and community characteristics. This research found out that shared knowledge dominated community local knowledge (77%). While common knowledge and specialized knowledge were sequentially 8% and 15%. The high score of shared value (77%) indicated that local knowledge was occurred in household level and not yet indicated in community level. Shared knowledge was found in 3 phases of the resilient community in dealing with disaster, namely mitigation, emergency response, and recovery phase. This research, therefore, has opened a new scientific discussion on the self-help concept in community-help concept in CBDRM concept development in Indonesia.

  7. A Fair and Balance Approach to the Mean

    ERIC Educational Resources Information Center

    Peters, Susan A.; Bennett, Victoria Miller; Young, Mandy; Watkins, Jonathan D.

    2016-01-01

    The mean can be interpreted as a fair-share value and as a balance point. Standards documents, including Common Core State Standards for Mathematics (CCSSM) (CCSSI 2010), suggest focusing on both interpretations. In this article, the authors propose a sequence of five activities to help students develop these understandings of the mean, and they…

  8. Enabling Leadership: Just Cycling Along. CRLRA Discussion Paper.

    ERIC Educational Resources Information Center

    Falk, Ian

    Conventional notions of leadership have focused on the leader alone rather than on the situation that leaders must enable. The common threads to successful rural community development in Australia over the last few decades lie in the way the community develops its stores of social capital, which is based on trust, shared values, networks, and…

  9. Yours, Mine, Theirs: Multiple Generations in Today's Workplace

    ERIC Educational Resources Information Center

    Grotophorst, Julie

    2011-01-01

    For the first time in history, four distinct generations are sharing the same workspace. Veterans, Baby Boomers, Gen-Xers, and Generation Y (the Millennials) are all bringing very different life experiences, expectations, and value systems to the work table. How do leaders bridge the gap among these generations and provide common ground on which…

  10. Study of Sharing Knowledge Resources in Business Schools

    ERIC Educational Resources Information Center

    Ranjan, Jayanthi

    2011-01-01

    Purpose: The purpose of this paper is to propose a common business school framework based on knowledge resources that are available in business schools. To support the arguments made based on review literature, the paper presents the holistic framework of knowledge resources in a business school and also provides a knowledge value chain in sharing…

  11. Creating and Sharing Annotated Bibliographies: One Way to Become Familiar with Exemplary Multicultural Literature

    ERIC Educational Resources Information Center

    Richards, Janet C.

    2015-01-01

    Teachers who meet Common Core recommendations about teaching with multicultural literature need to recognize the traditions, values, and customs of various cultures so they can make sound decisions about the authenticity of the books they select for their students. Furthermore, teachers who support students' literacy achievements with exemplary…

  12. Pastoral research: past, present, and future.

    PubMed

    Gleason, John J

    2004-01-01

    In healthcare environments of excellence, clinically trained chaplains are valued members of the medical treatment team. There are skills and values they hold in common with medicine and allied health disciplines: enhancing the health and well-being of the patient as a unity of body, mind, and spirit within a unique family and cultural system. This article examines the past, present, and future of pastoral research, including the chaplain's moral imperative to examine practice and to share what is found.

  13. Method of recommending items to a user based on user interest

    DOEpatents

    Bollen, John; Van De Sompel, Herbert

    2013-11-05

    Although recording of usage data is common in scholarly information services, its exploitation for the creation of value-added services remains limited due to concerns regarding, among others, user privacy, data validity, and the lack of accepted standards for the representation, sharing and aggregation of usage data. A technical, standards-based architecture for sharing usage information is presented. In this architecture, OpenURL-compliant linking servers aggregate usage information of a specific user community as it navigates the distributed information environment that it has access to. This usage information is made OAI-PMH harvestable so that usage information exposed by many linking servers can be aggregated to facilitate the creation of value-added services with a reach beyond that of a single community or a single information service.

  14. Usage based indicators to assess the impact of scholarly works: architecture and method

    DOEpatents

    Bollen, Johan [Santa Fe, NM; Van De Sompel, Herbert [Santa Fe, NM

    2012-03-13

    Although recording of usage data is common in scholarly information services, its exploitation for the creation of value-added services remains limited due to concerns regarding, among others, user privacy, data validity, and the lack of accepted standards for the representation, sharing and aggregation of usage data. A technical, standards-based architecture for sharing usage information is presented. In this architecture, OpenURL-compliant linking servers aggregate usage information of a specific user community as it navigates the distributed information environment that it has access to. This usage information is made OAI-PMH harvestable so that usage information exposed by many linking servers can be aggregated to facilitate the creation of value-added services with a reach beyond that of a single community or a single information service.

  15. Shared vision and autonomous motivation vs. financial incentives driving success in corporate acquisitions

    PubMed Central

    Clayton, Byron C.

    2015-01-01

    Successful corporate acquisitions require its managers to achieve substantial performance improvements in order to sufficiently cover acquisition premiums, the expected return of debt and equity investors, and the additional resources needed to capture synergies and accelerate growth. Acquirers understand that achieving the performance improvements necessary to cover these costs and create value for investors will most likely require a significant effort from mergers and acquisitions (M&A) management teams. This understanding drives the common and longstanding practice of offering hefty performance incentive packages to key managers, assuming that financial incentives will induce in-role and extra-role behaviors that drive organizational change and growth. The present study debunks the assumptions of this common M&A practice, providing quantitative evidence that shared vision and autonomous motivation are far more effective drivers of managerial performance than financial incentives. PMID:25610406

  16. Shared vision and autonomous motivation vs. financial incentives driving success in corporate acquisitions.

    PubMed

    Clayton, Byron C

    2014-01-01

    Successful corporate acquisitions require its managers to achieve substantial performance improvements in order to sufficiently cover acquisition premiums, the expected return of debt and equity investors, and the additional resources needed to capture synergies and accelerate growth. Acquirers understand that achieving the performance improvements necessary to cover these costs and create value for investors will most likely require a significant effort from mergers and acquisitions (M&A) management teams. This understanding drives the common and longstanding practice of offering hefty performance incentive packages to key managers, assuming that financial incentives will induce in-role and extra-role behaviors that drive organizational change and growth. The present study debunks the assumptions of this common M&A practice, providing quantitative evidence that shared vision and autonomous motivation are far more effective drivers of managerial performance than financial incentives.

  17. Stimulating collaboration between human and veterinary health care professionals.

    PubMed

    Eussen, Björn G M; Schaveling, Jaap; Dragt, Maria J; Blomme, Robert Jan

    2017-06-13

    Despite the need to control outbreaks of (emerging) zoonotic diseases and the need for added value in comparative/translational medicine, jointly addressed in the One Health approach [One health Initiative (n.d.a). About the One Health Initiative. http://www.onehealthinitiative.com/about.php . Accessed 13 September 2016], collaboration between human and veterinary health care professionals is limited. This study focuses on the social dilemma experienced by health care professionals and ways in which an interdisciplinary approach could be developed. Based on Gaertner and Dovidio's Common Ingroup Identity Model, a number of questionnaires were designed and tested; with PROGRESS, the relation between collaboration and common goal was assessed, mediated by decategorization, recategorization, mutual differentiation and knowledge sharing. This study confirms the Common Ingroup Identity Model stating that common goals stimulate collaboration. Decategorization and mutual differentiation proved to be significant in this relationship; recategorization and knowledge sharing mediate this relation. It can be concluded that the Common Ingroup Identity Model theory helps us to understand how health care professionals perceive the One Health initiative and how they can intervene in this process. In the One Health approach, professional associations could adopt a facilitating role.

  18. Activation of Operational Thinking during Arithmetic Practice Hinders Learning and Transfer

    ERIC Educational Resources Information Center

    Chesney, Dana L.; McNeil, Nicole M.

    2014-01-01

    Many children in the U.S. initially come to understand the equal sign operationally, as a symbol meaning "add up the numbers" rather than relationally, as an indication that the two sides of an equation share a common value. According to a change-resistance account (McNeil & Alibali, 2005b), children's operational ways of thinking…

  19. Preach Americanism! The Education of Immigrants during the Great War.

    ERIC Educational Resources Information Center

    Brumberg, Stephan F.

    For the United States, fighting World War I involved not only preparing young citizens to fight the enemy abroad, but rooting out alien enemies at home. The national consensus, believed vital to success, presupposed a common set of values, shared behaviors, and a high degree of identification with the nation. The more homogeneous the population,…

  20. Development of Creative Activity of Students in the System of the Organizational Culture of the Modern University

    ERIC Educational Resources Information Center

    Khairullina, Nursafa; Bakhtizin, Ramil; Gaisina, Lyutsiya; Kosintseva, Tamara; Belonozhko, Lidia

    2016-01-01

    Student creativity today is indicative of the successful operation of the higher education institution in the training of specialists. Organizational culture, being a complex of common and shared by all subjects of teaching and educational activity such as values, norms, beliefs, acts as an important integration factor influencing the creative…

  1. Characteristics of Jesuit Colleges and Universities in the United States: A Reciprocal Interdependence Analysis

    ERIC Educational Resources Information Center

    LaBelle, Jeffrey; Kendall, Daniel

    2016-01-01

    What common values do diverse Jesuit institutions share? In what ways are Jesuit colleges and universities working to maintain mission, identity, and traditions within the context of 21st-century higher education? To ground their response to these questions, the researchers first review the historical and ecclesial developments that have…

  2. Genomic research and wide data sharing: views of prospective participants.

    PubMed

    Trinidad, Susan Brown; Fullerton, Stephanie M; Bares, Julie M; Jarvik, Gail P; Larson, Eric B; Burke, Wylie

    2010-08-01

    Sharing study data within the research community generates tension between two important goods: promoting scientific goals and protecting the privacy interests of study participants. This study was designed to explore the perceptions, beliefs, and attitudes of research participants and possible future participants regarding genome-wide association studies and repository-based research. Focus group sessions with (1) current research participants, (2) surrogate decision-makers, and (3) three age-defined cohorts (18-34 years, 35-50, >50). Participants expressed a variety of opinions about the acceptability of wide sharing of genetic and phenotypic information for research purposes through large, publicly accessible data repositories. Most believed that making de-identified study data available to the research community is a social good that should be pursued. Privacy and confidentiality concerns were common, although they would not necessarily preclude participation. Many participants voiced reservations about sharing data with for-profit organizations. Trust is central in participants' views regarding data sharing. Further research is needed to develop governance models that enact the values of stewardship.

  3. Value of shared preclinical safety studies - The eTOX database.

    PubMed

    Briggs, Katharine; Barber, Chris; Cases, Montserrat; Marc, Philippe; Steger-Hartmann, Thomas

    2015-01-01

    A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) is presented. Species, duration of exposure and administration route data were analysed to assess if large enough subsets of homogenous data are available for building in silico predictive models. Prevalence of treatment related effects for the different types of findings recorded were analysed. The eTOX ontology was used to determine the most common treatment-related clinical chemistry and histopathology findings reported in the database. The data were then mined to evaluate sensitivity of established in vivo biomarkers for liver toxicity risk assessment. The value of the database to inform other drug development projects during early drug development is illustrated by a case study.

  4. 77 FR 38344 - Medallion Financial Corp.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... increasing the maximum number of shares of Applicant's common stock (``Common Stock'') available for issuance... Amended Director Plan. Under the Amended Director Plan, a maximum of 200,000 shares of Applicant's Common... shares of Applicant's Common Stock that may be issued to any one Eligible Director. The Amended Director...

  5. Revitalization of the Shared Commons: Education for Sustainability and Marginalized Cultures

    ERIC Educational Resources Information Center

    Glasson, George E.

    2010-01-01

    Education for sustainability provides a vision for revitalizing the environmental commons while preserving cultural traditions and human rights. What happens if the environmental commons is shared by two politically disparate and conflicting cultures? As in many shared common lands, what happens if one culture is dominant and represents a more…

  6. Teamwork: a concept analysis.

    PubMed

    Xyrichis, Andreas; Ream, Emma

    2008-01-01

    This paper is a report of an analysis of the concept of teamwork. Teamwork is seen as an important facilitator in delivering quality healthcare services internationally. However, research studies of teamwork in health care are criticized for lacking a basic conceptual understanding of what this concept represents. A universal definition for healthcare settings and professionals is missing from published literature. Walker and Avant's approach was used to guide this concept analysis. Literature searches used bibliographic databases (Medline, CINAHL, Web of Science, Proquest CSA), internet search engines (GoogleScholar), and hand searches. Literature published between 1976 and 2006 was reviewed but only material in English was included. Based on the analysis undertaken, teamwork is proposed as a dynamic process involving two or more healthcare professionals with complementary backgrounds and skills, sharing common health goals and exercising concerted physical and mental effort in assessing, planning, or evaluating patient care. This is accomplished through interdependent collaboration, open communication and shared decision-making, and generates value-added patient, organizational and staff outcomes. Praising the value of teamwork without a common understanding of what this concept represents endangers both research into this way of working and its effective utilization in practice. The proposed definition helps reconcile discrepancies between how this concept is understood by nurses and doctors, as well as allied health professionals. A common understanding can facilitate communication in educational, research and clinical settings and is imperative for improving clarity and validity of future research.

  7. Complex Dynamics of an Impulsive Control System in which Predator Species Share a Common Prey

    NASA Astrophysics Data System (ADS)

    Pei, Yongzhen; Liu, Shaoying; Li, Changguo

    2009-06-01

    In an ecosystem, multiple predator species often share a common prey and the interactions between the predators are neutral. In view of this fact, we propose a three-species prey-predator system with the functional responses and impulsive controls to model the process of pest management. It is proved that the system has a locally stable pest-eradication periodic solution under the assumption that the impulsive period is less than some critical value. In particular, two single control strategies (biological control alone or chemical control alone) are proposed. Finally, we compare three pest control strategies and find that if we choose narrow-spectrum pesticides that are targeted to a specific pest’s life cycle to kill the pest, then the combined strategy is preferable. Numerical results show that our system has complex dynamics including period-doubling bifurcation, quasi-periodic oscillation, chaos, intermittency and crises.

  8. 75 FR 65044 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Granting Approval to a Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-21

    ... market value of publicly held shares for common stock on the Capital Market range from $5 million to $15...-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Granting Approval to a Proposed Rule Change To Modify the Eligibility Criteria for the Second Compliance Period for a Bid Price Deficiency on the Nasdaq...

  9. Israel: Background and U.S. Relations

    DTIC Science & Technology

    2012-02-29

    security goals and have developed close relations based on common perceptions of shared democratic values and religious affinities. U.S. policymakers...and Christian religious claims in the city. Although Israel withdrew its permanent military presence from the Gaza Strip in 2005, it still controls...trends partly explain why Israel’s current Jewish population is “more nationalistic, religiously conservative, and hawkish on foreign policy and

  10. HIE sustainability secrets. NeHC report shares HIE success stories of alternate revenue streams and payer buy-in.

    PubMed

    Prestigiacomo, Jennifer

    2011-11-01

    Getting effective stakeholder engagement, including that of payers, and creating innovative value-added services that provide alternate revenue streams beyond basic subscription services, are just a couple of the common traits of the flourishing health information exchanges profiled in the sustainability report released in August by the National eHealth Collaborative.

  11. Surveying Borders, Boundaries, and Contested Spaces in Curriculum and Pedagogy. Curriculum and Pedagogy Series

    ERIC Educational Resources Information Center

    Reilly, Cole, Ed.; Russell, Victoria, Ed.; Chehayl, Laurel K., Ed.; McDermott, Morna M., Ed.

    2011-01-01

    The Curriculum and Pedagogy book series is an enactment of the mission and values espoused by the Curriculum and Pedagogy Group, an international educational organization serving those who share a common faith in democracy and a commitment to public moral leadership in schools and society. Accordingly, the mission of this series is to advance…

  12. 32 CFR 37.535 - How do I value cost sharing related to real property or equipment?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false How do I value cost sharing related to real... Evaluation Cost Sharing § 37.535 How do I value cost sharing related to real property or equipment? You rarely should accept values for cost sharing contributions of real property or equipment that are in...

  13. Distributed metadata servers for cluster file systems using shared low latency persistent key-value metadata store

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bent, John M.; Faibish, Sorin; Pedone, Jr., James M.

    A cluster file system is provided having a plurality of distributed metadata servers with shared access to one or more shared low latency persistent key-value metadata stores. A metadata server comprises an abstract storage interface comprising a software interface module that communicates with at least one shared persistent key-value metadata store providing a key-value interface for persistent storage of key-value metadata. The software interface module provides the key-value metadata to the at least one shared persistent key-value metadata store in a key-value format. The shared persistent key-value metadata store is accessed by a plurality of metadata servers. A metadata requestmore » can be processed by a given metadata server independently of other metadata servers in the cluster file system. A distributed metadata storage environment is also disclosed that comprises a plurality of metadata servers having an abstract storage interface to at least one shared persistent key-value metadata store.« less

  14. Covariance Bell inequalities

    NASA Astrophysics Data System (ADS)

    Pozsgay, Victor; Hirsch, Flavien; Branciard, Cyril; Brunner, Nicolas

    2017-12-01

    We introduce Bell inequalities based on covariance, one of the most common measures of correlation. Explicit examples are discussed, and violations in quantum theory are demonstrated. A crucial feature of these covariance Bell inequalities is their nonlinearity; this has nontrivial consequences for the derivation of their local bound, which is not reached by deterministic local correlations. For our simplest inequality, we derive analytically tight bounds for both local and quantum correlations. An interesting application of covariance Bell inequalities is that they can act as "shared randomness witnesses": specifically, the value of the Bell expression gives device-independent lower bounds on both the dimension and the entropy of the shared random variable in a local model.

  15. Development of a Framework Based on Reflective MCDA to Support Patient-Clinician Shared Decision-Making: The Case of the Management of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET) in the United States.

    PubMed

    Wagner, Monika; Samaha, Dima; Khoury, Hanane; O'Neil, William M; Lavoie, Louis; Bennetts, Liga; Badgley, Danielle; Gabriel, Sylvie; Berthon, Anthony; Dolan, James; Kulke, Matthew H; Goetghebeur, Mireille

    2018-01-01

    Well- or moderately differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are often slow-growing, and some patients with unresectable, asymptomatic, non-functioning tumors may face the choice between watchful waiting (WW), or somatostatin analogues (SSA) to delay progression. We developed a comprehensive multi-criteria decision analysis (MCDA) framework to help patients and physicians clarify their values and preferences, consider each decision criterion, and support communication and shared decision-making. The framework was adapted from a generic MCDA framework (EVIDEM) with patient and clinician input. During a workshop, patients and clinicians expressed their individual values and preferences (criteria weights) and, on the basis of two scenarios (treatment vs WW; SSA-1 [lanreotide] vs SSA-2 [octreotide]) with evidence from a literature review, expressed how consideration of each criterion would impact their decision in favor of either option (score), and shared their knowledge and insights verbally and in writing. The framework included benefit-risk criteria and modulating factors, such as disease severity, quality of evidence, costs, and constraints. Overall and progression-free survival being most important, criteria weights ranged widely, highlighting variations in individual values and the need to share them. Scoring and considering each criterion prompted a rich exchange of perspectives and uncovered individual assumptions and interpretations. At the group level, type of benefit, disease severity, effectiveness, and quality of evidence favored treatment; cost aspects favored WW (scenario 1). For scenario 2, most criteria did not favor either option. Patients and clinicians consider many aspects in decision-making. The MCDA framework provided a common interpretive frame to structure this complexity, support individual reflection, and share perspectives. Ipsen Pharma.

  16. Theory-based metrological traceability in education: A reading measurement network.

    PubMed

    Fisher, William P; Stenner, A Jackson

    2016-10-01

    Huge resources are invested in metrology and standards in the natural sciences, engineering, and across a wide range of commercial technologies. Significant positive returns of human, social, environmental, and economic value on these investments have been sustained for decades. Proven methods for calibrating test and survey instruments in linear units are readily available, as are data- and theory-based methods for equating those instruments to a shared unit. Using these methods, metrological traceability is obtained in a variety of commercially available elementary and secondary English and Spanish language reading education programs in the U.S., Canada, Mexico, and Australia. Given established historical patterns, widespread routine reproduction of predicted text-based and instructional effects expressed in a common language and shared frame of reference may lead to significant developments in theory and practice. Opportunities for systematic implementations of teacher-driven lean thinking and continuous quality improvement methods may be of particular interest and value.

  17. Optimizing occupational exposure measurement strategies when estimating the log-scale arithmetic mean value--an example from the reinforced plastics industry.

    PubMed

    Lampa, Erik G; Nilsson, Leif; Liljelind, Ingrid E; Bergdahl, Ingvar A

    2006-06-01

    When assessing occupational exposures, repeated measurements are in most cases required. Repeated measurements are more resource intensive than a single measurement, so careful planning of the measurement strategy is necessary to assure that resources are spent wisely. The optimal strategy depends on the objectives of the measurements. Here, two different models of random effects analysis of variance (ANOVA) are proposed for the optimization of measurement strategies by the minimization of the variance of the estimated log-transformed arithmetic mean value of a worker group, i.e. the strategies are optimized for precise estimation of that value. The first model is a one-way random effects ANOVA model. For that model it is shown that the best precision in the estimated mean value is always obtained by including as many workers as possible in the sample while restricting the number of replicates to two or at most three regardless of the size of the variance components. The second model introduces the 'shared temporal variation' which accounts for those random temporal fluctuations of the exposure that the workers have in common. It is shown for that model that the optimal sample allocation depends on the relative sizes of the between-worker component and the shared temporal component, so that if the between-worker component is larger than the shared temporal component more workers should be included in the sample and vice versa. The results are illustrated graphically with an example from the reinforced plastics industry. If there exists a shared temporal variation at a workplace, that variability needs to be accounted for in the sampling design and the more complex model is recommended.

  18. A Game Theoretic Framework for Analyzing Re-Identification Risk

    PubMed Central

    Wan, Zhiyu; Vorobeychik, Yevgeniy; Xia, Weiyi; Clayton, Ellen Wright; Kantarcioglu, Murat; Ganta, Ranjit; Heatherly, Raymond; Malin, Bradley A.

    2015-01-01

    Given the potential wealth of insights in personal data the big databases can provide, many organizations aim to share data while protecting privacy by sharing de-identified data, but are concerned because various demonstrations show such data can be re-identified. Yet these investigations focus on how attacks can be perpetrated, not the likelihood they will be realized. This paper introduces a game theoretic framework that enables a publisher to balance re-identification risk with the value of sharing data, leveraging a natural assumption that a recipient only attempts re-identification if its potential gains outweigh the costs. We apply the framework to a real case study, where the value of the data to the publisher is the actual grant funding dollar amounts from a national sponsor and the re-identification gain of the recipient is the fine paid to a regulator for violation of federal privacy rules. There are three notable findings: 1) it is possible to achieve zero risk, in that the recipient never gains from re-identification, while sharing almost as much data as the optimal solution that allows for a small amount of risk; 2) the zero-risk solution enables sharing much more data than a commonly invoked de-identification policy of the U.S. Health Insurance Portability and Accountability Act (HIPAA); and 3) a sensitivity analysis demonstrates these findings are robust to order-of-magnitude changes in player losses and gains. In combination, these findings provide support that such a framework can enable pragmatic policy decisions about de-identified data sharing. PMID:25807380

  19. Social and monetary reward learning engage overlapping neural substrates.

    PubMed

    Lin, Alice; Adolphs, Ralph; Rangel, Antonio

    2012-03-01

    Learning to make choices that yield rewarding outcomes requires the computation of three distinct signals: stimulus values that are used to guide choices at the time of decision making, experienced utility signals that are used to evaluate the outcomes of those decisions and prediction errors that are used to update the values assigned to stimuli during reward learning. Here we investigated whether monetary and social rewards involve overlapping neural substrates during these computations. Subjects engaged in two probabilistic reward learning tasks that were identical except that rewards were either social (pictures of smiling or angry people) or monetary (gaining or losing money). We found substantial overlap between the two types of rewards for all components of the learning process: a common area of ventromedial prefrontal cortex (vmPFC) correlated with stimulus value at the time of choice and another common area of vmPFC correlated with reward magnitude and common areas in the striatum correlated with prediction errors. Taken together, the findings support the hypothesis that shared anatomical substrates are involved in the computation of both monetary and social rewards. © The Author (2011). Published by Oxford University Press.

  20. The Puerto Rico Gap Analysis Project Volume 1: land cover, vertebrate species distributions, and land stewardship

    Treesearch

    W. A. Gould; C. Alarcon; B. Fevold; M.E. Jimenez; S. Martinuzzi; G. Potts; M. Quinones; M. Solórzano; E. Ventosa

    2008-01-01

    Puerto Rico faces a number of problems common to much of the world. Population is increasing while land area is not, and there are reassessments of land use policy and practice to accommodate growing populations, shifting economies, and changing public value systems. Puerto Rico shares similarities with the Eastern United States with its history of agricultural...

  1. Guia para Padres: Acceso a los Grupos de Padres (Accessing Parent Groups: A Parent's Guide).

    ERIC Educational Resources Information Center

    Interstate Research Associates, McLean, VA.

    This guide, in Spanish, notes the value of parent groups for parents of children with disabilities, as they offer parents a place and a means to share information, give and receive emotional support, and work as a team to address common concerns. Typical activities of a parent group are listed, and ways of identifying parent groups that exist…

  2. The Reasons Young Children Give to Peers When Explaining Their Judgments of Moral and Conventional Rules

    ERIC Educational Resources Information Center

    Mammen, Maria; Köymen, Bahar; Tomasello, Michael

    2018-01-01

    Moral justifications work, when they do, by invoking values that are shared in the common ground of the interlocutors. We asked 3- and 5-year-old peer dyads (N = 144) to identify and punish norm transgressors. In the moral condition, the transgressor violated a moral norm (e.g., by stealing); in the social rules condition, she/he violated a…

  3. Half-Full or Half-Empty? Health Care, Child Care, and Youth Programs for Asian American Children in New York City.

    ERIC Educational Resources Information Center

    White, Andrew; Lee, Jessica; Lee, Larry

    This report examines the availability of health care, child care, and youth programs for Asian Americans in New York City. The Asian American community currently makes up 10 percent of the city population. Asian New Yorkers represent diverse cultures and languages but share certain underlying values and challenges. One commonality is their…

  4. Values in Persons With Schizophrenia

    PubMed Central

    Stanghellini, Giovanni; Ballerini, Massimo

    2007-01-01

    This is an explorative study on the values of persons with schizophrenia based on transcripts of individual therapy sessions conducted for 40 persons with chart diagnoses of schizophrenia or schizotypal disorder. Values are action-guiding attitudes that subject human activities to be worthy of praise or blame. The schizophrenic value system conveys an overall crisis of common sense. The outcome of this has been designated as antagonomia and idionomia. Antagonomia reflects the choice to take an eccentric stand in the face of commonly shared assumptions and the here and now “other.” Idionomia reflects the feeling of the radical uniqueness and exceptionality of one's being with respect to common sense and the other human beings. This sentiment of radical exceptionality is felt as a “gift,” often in view of an eschatological mission or a vocation to a superior, novel, metaphysical understanding of the world. The aim of this study is neither establishing new diagnostic criteria nor suggesting that values play an etio-pathogenetical role in the development of schizophrenia but improving our understanding of the “meaning” of schizophrenic experiences and beliefs, and by doing so reducing stigmatization, and enhancing the specificity and validity of “psychotic symptoms” (especially bizarre delusions) and of “social and occupational dysfunction” through a detailed description of the anthropological and existential matrix they arise from. PMID:16940339

  5. Basic math in monkeys and college students.

    PubMed

    Cantlon, Jessica F; Brannon, Elizabeth M

    2007-12-01

    Adult humans possess a sophisticated repertoire of mathematical faculties. Many of these capacities are rooted in symbolic language and are therefore unlikely to be shared with nonhuman animals. However, a subset of these skills is shared with other animals, and this set is considered a cognitive vestige of our common evolutionary history. Current evidence indicates that humans and nonhuman animals share a core set of abilities for representing and comparing approximate numerosities nonverbally; however, it remains unclear whether nonhuman animals can perform approximate mental arithmetic. Here we show that monkeys can mentally add the numerical values of two sets of objects and choose a visual array that roughly corresponds to the arithmetic sum of these two sets. Furthermore, monkeys' performance during these calculations adheres to the same pattern as humans tested on the same nonverbal addition task. Our data demonstrate that nonverbal arithmetic is not unique to humans but is instead part of an evolutionarily primitive system for mathematical thinking shared by monkeys.

  6. An ethics training specific for European public health.

    PubMed

    Camps, Victoria; Hernández-Aguado, Ildefonso; Puyol, Angel; Segura, Andreu

    2015-01-01

    Training in public health ethics is not at the core of public health programmes in Europe. The fruitful progress of the United States could stimulate the European schools of public health and other academic institutions to develop specifically European teaching programmes for ethics that embrace both transatlantic innovations and some adaptations based on the evolution of moral values in European societies. This paper reviews the arguments for a European public health ethics curriculum and recommends the main features of such a programme. Europe shares common values and, above all, the three major ethical principles that were socially and politically crystallized by the French Revolution: liberty, equality, and fraternity. Fraternity, otherwise known as solidarity, although rarely mentioned in the literature on ethical issues, is the moral value that best defines the European concept of public health expressed as a common good, mutual aid, and a collective or shared responsibility for health of the population. Specific political motivations were responsible for the origin of European health systems and for current policy proposals led by the European Union, such as Europe's commitments, at least in theory, to: reduce social inequities in health and to develop the health in all policies approach. These and other initiatives, albeit not exclusively European, have political and legal repercussions that pose unique ethical challenges. Europe combines homogeneity in social determinants of health with heterogeneity in public health approaches and interventions. It is therefore necessary to develop training in ethics and good government for all public health workers in Europe, especially since a large segment of the population's health depends on actions and decisions adopted by the European Commission and its regulatory agencies as well as for non EU European Region countries. Based on these arguments, the paper concludes with several recommendations for a common nucleus for the ethics curriculum in Europe.

  7. Managing Ethical Difficulties in Healthcare: Communicating in Inter-professional Clinical Ethics Support Sessions.

    PubMed

    Grönlund, Catarina Fischer; Dahlqvist, Vera; Zingmark, Karin; Sandlund, Mikael; Söderberg, Anna

    2016-12-01

    Several studies show that healthcare professionals need to communicate inter-professionally in order to manage ethical difficulties. A model of clinical ethics support (CES) inspired by Habermas' theory of discourse ethics has been developed by our research group. In this version of CES sessions healthcare professionals meet inter-professionally to communicate and reflect on ethical difficulties in a cooperative manner with the aim of reaching communicative agreement or reflective consensus. In order to understand the course of action during CES, the aim of this study was to describe the communication of value conflicts during a series of inter-professional CES sessions. Ten audio- and video-recorded CES sessions were conducted over eight months and were analyzed by using the video analysis tool Transana and qualitative content analysis. The results showed that during the CES sessions the professionals as a group moved through the following five phases: a value conflict expressed as feelings of frustration, sharing disempowerment and helplessness, the revelation of the value conflict, enhancing realistic expectations, seeing opportunities to change the situation instead of obstacles. In the course of CES, the professionals moved from an individual interpretation of the situation to a common, new understanding and then to a change in approach. An open and permissive communication climate meant that the professionals dared to expose themselves, share their feelings, face their own emotions, and eventually arrive at a mutual shared reality. The value conflict was not only revealed but also resolved.

  8. 77 FR 26052 - Invesco Total Property Market Income Fund, et al.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... price of such Fund's common shares at a particular point in time, or a fixed percentage of NAV at a... broker, dealer, bank or other person (``financial intermediary'') holds common shares issued by a Fund in... outstanding common shares as frequently as monthly in any one taxable year, and as frequently as distributions...

  9. Simple Math is Enough: Two Examples of Inferring Functional Associations from Genomic Data

    NASA Technical Reports Server (NTRS)

    Liang, Shoudan

    2003-01-01

    Non-random features in the genomic data are usually biologically meaningful. The key is to choose the feature well. Having a p-value based score prioritizes the findings. If two proteins share a unusually large number of common interaction partners, they tend to be involved in the same biological process. We used this finding to predict the functions of 81 un-annotated proteins in yeast.

  10. Managing diversity: the best for everyone.

    PubMed

    Greenwald, H P

    1994-01-01

    Howard Greenwald argues that social diversity can be transformed from a "problem" to a solution if leaders can fashion ways of incorporating the commonalities across different groups in the population. Core values of "hard work, just rewards, and personal liberty" can form the foundation of shared understandings among persons of different nativity, culture, and gender. At the same time, Greenwald notes the importance of designing different strategies for different people.

  11. Explaining effervescence: Investigating the relationship between shared social identity and positive experience in crowds

    PubMed Central

    Hopkins, Nick; Reicher, Stephen D.; Khan, Sammyh S.; Tewari, Shruti; Srinivasan, Narayanan; Stevenson, Clifford

    2016-01-01

    We investigated the intensely positive emotional experiences arising from participation in a large-scale collective event. We predicted such experiences arise when those attending a collective event are (1) able to enact their valued collective identity and (2) experience close relations with other participants. In turn, we predicted both of these to be more likely when participants perceived crowd members to share a common collective identity. We investigated these predictions in a survey of pilgrims (N = 416) attending a month-long Hindu pilgrimage festival in north India. We found participants' perceptions of a shared identity amongst crowd members had an indirect effect on their positive experience at the event through (1) increasing participants' sense that they were able to enact their collective identity and (2) increasing the sense of intimacy with other crowd members. We discuss the implications of these data for how crowd emotion should be conceptualised. PMID:25787295

  12. Involvement as inclusion? Shared decision-making in social work practice in Israel: a qualitative account.

    PubMed

    Levin, Lia

    2015-03-01

    Shared decision-making (SDM), a representation of shared knowledge and power between social workers and their clients, is gaining popularity and prevalence in social services around the world. In many senses, SDM reflects values traditionally associated with social work and service provision, such as equality and anti-discrimination. In the complex context of social problem-solving, however, the relationship between SDM, social workers and their clients is multi-faceted and deserves particular attention. The current study examined SDM and the dilemmas it entails through interviews conducted in 2012 with 77 Israeli social workers and policy makers whose responses were analysed according to the guiding principles of descriptive phenomenological content analysis and dialogical commonality. Participants' responses represent notions of hope, change, identity and choice. Findings are discussed in correspondence with current and recent trends in Israeli social services, and the social work profession in Israel. © 2014 John Wiley & Sons Ltd.

  13. The Influence of Information Acquisition on the Complex Dynamics of Market Competition

    NASA Astrophysics Data System (ADS)

    Guo, Zhanbing; Ma, Junhai

    In this paper, we build a dynamical game model with three bounded rational players (firms) to study the influence of information on the complex dynamics of market competition, where useful information is about rival’s real decision. In this dynamical game model, one information-sharing team is composed of two firms, they acquire and share the information about their common competitor, however, they make their own decisions separately, where the amount of information acquired by this information-sharing team will determine the estimation accuracy about the rival’s real decision. Based on this dynamical game model and some creative 3D diagrams, the influence of the amount of information on the complex dynamics of market competition such as local dynamics, global dynamics and profits is studied. These results have significant theoretical and practical values to realize the influence of information.

  14. Explaining effervescence: Investigating the relationship between shared social identity and positive experience in crowds.

    PubMed

    Hopkins, Nick; Reicher, Stephen D; Khan, Sammyh S; Tewari, Shruti; Srinivasan, Narayanan; Stevenson, Clifford

    2016-01-01

    We investigated the intensely positive emotional experiences arising from participation in a large-scale collective event. We predicted such experiences arise when those attending a collective event are (1) able to enact their valued collective identity and (2) experience close relations with other participants. In turn, we predicted both of these to be more likely when participants perceived crowd members to share a common collective identity. We investigated these predictions in a survey of pilgrims (N = 416) attending a month-long Hindu pilgrimage festival in north India. We found participants' perceptions of a shared identity amongst crowd members had an indirect effect on their positive experience at the event through (1) increasing participants' sense that they were able to enact their collective identity and (2) increasing the sense of intimacy with other crowd members. We discuss the implications of these data for how crowd emotion should be conceptualised.

  15. Relationship of Inglehart's and Schwartz's value dimensions revisited.

    PubMed

    Dobewall, Henrik; Strack, Micha

    2014-08-01

    This study examines the relationship between Inglehart's and Schwartz's value dimensions-both at the individual and the country levels. By rotating one set of items towards the other, we show that these value dimensions have more in common than previously reported. The ranking of countries (N = 47) based on Schwartz's Embeddedness--Autonomy and the Survival--Self-Expression dimensions reached a maximum of similarity, r = .82, after rotating Inglehart's factor scores 27 degrees clockwise. The correlation between the other pair of dimensions (Schwartz's Hierarchy-Mastery--Egalitarianism-Harmony and Inglehart's Traditional--Secular-Rational values) was near zero before and after rotation. At the individual level (N = 46,444), positive correlations were found for Schwartz's Conservation--Openness dimension with both of Inglehart's dimensions (Survival--Self-Expression and Traditional--Secular-Rational values). The highest correlation with this Schwartz dimension was obtained at the Secular-Rational/Self-Expression diagonal, r = .24, after rotating the factor scores 45 degrees clockwise. We conclude that Schwartz's and Inglehart's originally proposed two-dimensional value structures share one dimension at the country level and some commonality at the individual level, whereas the respective other pair of dimensions seem to be more or less unrelated. © 2013 International Union of Psychological Science.

  16. Advancing Collaboration through Hydrologic Data and Model Sharing

    NASA Astrophysics Data System (ADS)

    Tarboton, D. G.; Idaszak, R.; Horsburgh, J. S.; Ames, D. P.; Goodall, J. L.; Band, L. E.; Merwade, V.; Couch, A.; Hooper, R. P.; Maidment, D. R.; Dash, P. K.; Stealey, M.; Yi, H.; Gan, T.; Castronova, A. M.; Miles, B.; Li, Z.; Morsy, M. M.

    2015-12-01

    HydroShare is an online, collaborative system for open sharing of hydrologic data, analytical tools, and models. It supports the sharing of and collaboration around "resources" which are defined primarily by standardized metadata, content data models for each resource type, and an overarching resource data model based on the Open Archives Initiative's Object Reuse and Exchange (OAI-ORE) standard and a hierarchical file packaging system called "BagIt". HydroShare expands the data sharing capability of the CUAHSI Hydrologic Information System by broadening the classes of data accommodated to include geospatial and multidimensional space-time datasets commonly used in hydrology. HydroShare also includes new capability for sharing models, model components, and analytical tools and will take advantage of emerging social media functionality to enhance information about and collaboration around hydrologic data and models. It also supports web services and server/cloud based computation operating on resources for the execution of hydrologic models and analysis and visualization of hydrologic data. HydroShare uses iRODS as a network file system for underlying storage of datasets and models. Collaboration is enabled by casting datasets and models as "social objects". Social functions include both private and public sharing, formation of collaborative groups of users, and value-added annotation of shared datasets and models. The HydroShare web interface and social media functions were developed using the Django web application framework coupled to iRODS. Data visualization and analysis is supported through the Tethys Platform web GIS software stack. Links to external systems are supported by RESTful web service interfaces to HydroShare's content. This presentation will introduce the HydroShare functionality developed to date and describe ongoing development of functionality to support collaboration and integration of data and models.

  17. The role of personal values in children's costly sharing and non-costly giving.

    PubMed

    Abramson, Lior; Daniel, Ella; Knafo-Noam, Ariel

    2018-01-01

    This study examined whether children's values, global and abstract motivations serving as guiding principles, are organized similarly to those of adults, whether values can predict individual differences in children's sharing behaviors, and whether the normative nature of the situation influences the expression of these individual differences. Children (N=243, ages 5-12years) participated in a values ranking task as part of a visit to a science museum. The majority of children (n=150) also participated in a task examining costly sharing (i.e., sharing that results in giving up part of one's own resources) and non-costly giving (i.e., giving that does not influence one's own share). Starting from 5years of age, children showed a structure of values similar to that of adolescents and adults, specifically contrasting preferences for opposing values (i.e., self-transcendence with self-enhancement and openness to change with conservation). Importance given to self-transcendence values related positively to costly sharing but not to non-costly giving, indicating that in situations where it is more normative to share, individual differences in values are less expressed in children's actual sharing. In addition, children's sex and age moderated the relation between values and behavior. Children's values are an important aspect of their developing personalities. Taking them into consideration can greatly promote the research of prosocial and normative development as well as our understanding of individual differences in children's behavior. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Do neighboring lakes share common taxa of bacterioplankton? Comparison of 16S rDNA fingerprints and sequences from three geographic regions.

    PubMed

    Lindström, E S; Leskinen, E

    2002-07-01

    Bacterioplankton community composition was studied in 12 lakes in three different geographic regions in Scandinavia using denaturing gradient gel electrophoresis (DGGE) and sequencing of 16S rDNA. Area-specific abundant taxa were found in the lakes in two of the regions. In the region of Uppland the lakes had an alpha-proteobacterium, belonging to the subgroup Alpha V in common. The Alpha V bacteria appeared to be favored by neutral or higher pH values. The lakes in Lappland were found to harbor Actinobacteria, which appeared to be favored in bog lakes. No abundant taxon was found to be in common for the lakes in Svalbard, the third region studied.

  19. A Secret 3D Model Sharing Scheme with Reversible Data Hiding Based on Space Subdivision

    NASA Astrophysics Data System (ADS)

    Tsai, Yuan-Yu

    2016-03-01

    Secret sharing is a highly relevant research field, and its application to 2D images has been thoroughly studied. However, secret sharing schemes have not kept pace with the advances of 3D models. With the rapid development of 3D multimedia techniques, extending the application of secret sharing schemes to 3D models has become necessary. In this study, an innovative secret 3D model sharing scheme for point geometries based on space subdivision is proposed. Each point in the secret point geometry is first encoded into a series of integer values that fall within [0, p - 1], where p is a predefined prime number. The share values are derived by substituting the specified integer values for all coefficients of the sharing polynomial. The surface reconstruction and the sampling concepts are then integrated to derive a cover model with sufficient model complexity for each participant. Finally, each participant has a separate 3D stego model with embedded share values. Experimental results show that the proposed technique supports reversible data hiding and the share values have higher levels of privacy and improved robustness. This technique is simple and has proven to be a feasible secret 3D model sharing scheme.

  20. Agile Data Curation Case Studies Leading to the Identification and Development of Data Curation Design Patterns

    NASA Astrophysics Data System (ADS)

    Benedict, K. K.; Lenhardt, W. C.; Young, J. W.; Gordon, L. C.; Hughes, S.; Santhana Vannan, S. K.

    2017-12-01

    The planning for and development of efficient workflows for the creation, reuse, sharing, documentation, publication and preservation of research data is a general challenge that research teams of all sizes face. In response to: requirements from funding agencies for full-lifecycle data management plans that will result in well documented, preserved, and shared research data products increasing requirements from publishers for shared data in conjunction with submitted papers interdisciplinary research team's needs for efficient data sharing within projects, and increasing reuse of research data for replication and new, unanticipated research, policy development, and public use alternative strategies to traditional data life cycle approaches must be developed and shared that enable research teams to meet these requirements while meeting the core science objectives of their projects within the available resources. In support of achieving these goals, the concept of Agile Data Curation has been developed in which there have been parallel activities in support of 1) identifying a set of shared values and principles that underlie the objectives of agile data curation, 2) soliciting case studies from the Earth science and other research communities that illustrate aspects of what the contributors consider agile data curation methods and practices, and 3) identifying or developing design patterns that are high-level abstractions from successful data curation practice that are related to common data curation problems for which common solution strategies may be employed. This paper provides a collection of case studies that have been contributed by the Earth science community, and an initial analysis of those case studies to map them to emerging shared data curation problems and their potential solutions. Following the initial analysis of these problems and potential solutions, existing design patterns from software engineering and related disciplines are identified as a starting point for the development of a catalog of data curation design patterns that may be reused in the design and execution of new data curation processes.

  1. Genetic pleiotropy explains associations between musical auditory discrimination and intelligence.

    PubMed

    Mosing, Miriam A; Pedersen, Nancy L; Madison, Guy; Ullén, Fredrik

    2014-01-01

    Musical aptitude is commonly measured using tasks that involve discrimination of different types of musical auditory stimuli. Performance on such different discrimination tasks correlates positively with each other and with intelligence. However, no study to date has explored these associations using a genetically informative sample to estimate underlying genetic and environmental influences. In the present study, a large sample of Swedish twins (N = 10,500) was used to investigate the genetic architecture of the associations between intelligence and performance on three musical auditory discrimination tasks (rhythm, melody and pitch). Phenotypic correlations between the tasks ranged between 0.23 and 0.42 (Pearson r values). Genetic modelling showed that the covariation between the variables could be explained by shared genetic influences. Neither shared, nor non-shared environment had a significant effect on the associations. Good fit was obtained with a two-factor model where one underlying shared genetic factor explained all the covariation between the musical discrimination tasks and IQ, and a second genetic factor explained variance exclusively shared among the discrimination tasks. The results suggest that positive correlations among musical aptitudes result from both genes with broad effects on cognition, and genes with potentially more specific influences on auditory functions.

  2. Genetic Pleiotropy Explains Associations between Musical Auditory Discrimination and Intelligence

    PubMed Central

    Mosing, Miriam A.; Pedersen, Nancy L.; Madison, Guy; Ullén, Fredrik

    2014-01-01

    Musical aptitude is commonly measured using tasks that involve discrimination of different types of musical auditory stimuli. Performance on such different discrimination tasks correlates positively with each other and with intelligence. However, no study to date has explored these associations using a genetically informative sample to estimate underlying genetic and environmental influences. In the present study, a large sample of Swedish twins (N = 10,500) was used to investigate the genetic architecture of the associations between intelligence and performance on three musical auditory discrimination tasks (rhythm, melody and pitch). Phenotypic correlations between the tasks ranged between 0.23 and 0.42 (Pearson r values). Genetic modelling showed that the covariation between the variables could be explained by shared genetic influences. Neither shared, nor non-shared environment had a significant effect on the associations. Good fit was obtained with a two-factor model where one underlying shared genetic factor explained all the covariation between the musical discrimination tasks and IQ, and a second genetic factor explained variance exclusively shared among the discrimination tasks. The results suggest that positive correlations among musical aptitudes result from both genes with broad effects on cognition, and genes with potentially more specific influences on auditory functions. PMID:25419664

  3. HydroShare: A Platform for Collaborative Data and Model Sharing in Hydrology

    NASA Astrophysics Data System (ADS)

    Tarboton, D. G.; Idaszak, R.; Horsburgh, J. S.; Ames, D. P.; Goodall, J. L.; Couch, A.; Hooper, R. P.; Dash, P. K.; Stealey, M.; Yi, H.; Bandaragoda, C.; Castronova, A. M.

    2017-12-01

    HydroShare is an online, collaboration system for sharing of hydrologic data, analytical tools, and models. It supports the sharing of and collaboration around "resources" which are defined by standardized content types for data formats and models commonly used in hydrology. With HydroShare you can: Share your data and models with colleagues; Manage who has access to the content that you share; Share, access, visualize and manipulate a broad set of hydrologic data types and models; Use the web services application programming interface (API) to program automated and client access; Publish data and models and obtain a citable digital object identifier (DOI); Aggregate your resources into collections; Discover and access data and models published by others; Use web apps to visualize, analyze and run models on data in HydroShare. This presentation will describe the functionality and architecture of HydroShare highlighting its use as a virtual environment supporting education and research. HydroShare has components that support: (1) resource storage, (2) resource exploration, and (3) web apps for actions on resources. The HydroShare data discovery, sharing and publishing functions as well as HydroShare web apps provide the capability to analyze data and execute models completely in the cloud (servers remote from the user) overcoming desktop platform limitations. The HydroShare GIS app provides a basic capability to visualize spatial data. The HydroShare JupyterHub Notebook app provides flexible and documentable execution of Python code snippets for analysis and modeling in a way that results can be shared among HydroShare users and groups to support research collaboration and education. We will discuss how these developments can be used to support different types of educational efforts in Hydrology where being completely web based is of value in an educational setting as students can all have access to the same functionality regardless of their computer.

  4. The HTA Core Model®-10 Years of Developing an International Framework to Share Multidimensional Value Assessment.

    PubMed

    Kristensen, Finn Børlum; Lampe, Kristian; Wild, Claudia; Cerbo, Marina; Goettsch, Wim; Becla, Lidia

    2017-02-01

    The HTA Core Model ® as a science-based framework for assessing dimensions of value was developed as a part of the European network for Health Technology Assessment project in the period 2006 to 2008 to facilitate production and sharing of health technology assessment (HTA) information, such as evidence on efficacy and effectiveness and patient aspects, to inform decisions. It covers clinical value as well as organizational, economic, and patient aspects of technologies and has been field-tested in two consecutive joint actions in the period 2010 to 2016. A large number of HTA institutions were involved in the work. The model has undergone revisions and improvement after iterations of piloting and can be used in a local, national, or international context to produce structured HTA information that can be taken forward by users into their own frameworks to fit their specific needs when informing decisions on technology. The model has a broad scope and offers a common ground to various stakeholders through offering a standard structure and a transparent set of proposed HTA questions. It consists of three main components: 1) the HTA ontology, 2) methodological guidance, and 3) a common reporting structure. It covers domains such as effectiveness, safety, and economics, and also includes domains covering organizational, patient, social, and legal aspects. There is a full model and a focused rapid relative effectiveness assessment model, and a third joint action is to continue till 2020. The HTA Core Model is now available for everyone around the world as a framework for assessing value. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  5. The Impact of Socio-Cultural Differences on Educational Values: A Comparison of the Pedagogy of Michael Oakeshott and John McGahern

    ERIC Educational Resources Information Center

    Williams, Kevin

    2017-01-01

    The year 2016 marked the tenth anniversary of the death of John McGahern (born 1934), the widely acclaimed Irish author. There is a shared temper of mind and several common strands in the work of McGahern and that of the English philosopher, Michael Oakeshott (1900-1990). Despite the very different cultural environments in which they grew up and…

  6. The Iranian Century: The Tension between Iran and the Gulf States

    DTIC Science & Technology

    2011-12-01

    IBP USA, Iran Foreign Policy & Government Guide. 23 Ibid. 24 Ibid. 25 Ibid. 16 homes, and factories whose value was estimated to be in the...extracting more than its fair share from a common gas field 40 Joseph K. Grieboski, “Iran’s Nukes...contains 23 percent of the world’s gas reserves. The Middle East accounts for the largest increase in regional natural gas production from 2007 to

  7. Revitalization of the shared commons: education for sustainability and marginalized cultures

    NASA Astrophysics Data System (ADS)

    Glasson, George E.

    2010-06-01

    Education for sustainability provides a vision for revitalizing the environmental commons while preserving cultural traditions and human rights. What happens if the environmental commons is shared by two politically disparate and conflicting cultures? As in many shared common lands, what happens if one culture is dominant and represents a more affluent society with more resources and educational opportunities? In the case of the Tal and Alkaher study (Cult Stud Sci Edu, 2009), asymmetric power differences between the dominant Israeli society and the minority Arab population yielded different environmental narratives and perceptions of students involved in learning about a mediated conflict in national park land. Similarly, marginalized indigenous cultures in Malawi, Africa share common lands with the dominant European landowners but have distinctly different environmental narratives. Although indigenous ways of living with nature contribute to the sustainability of the environment and culture, African funds of knowledge are conspicuously absent from the Eurocentric school science curriculum. In contrast, examples of experiential learning and recent curriculum development efforts in sustainability science in Malawi are inclusive of indigenous knowledge and practices and are essential for revitalizing the shared commons.

  8. Supporting shared decision making beyond consumer-prescriber interactions: Initial development of the CommonGround fidelity scale

    PubMed Central

    Fukui, Sadaaki; Salyers, Michelle P.; Rapp, Charlie; Goscha, Rick; Young, Leslie; Mabry, Ally

    2015-01-01

    Shared decision-making has become a central tenet of recovery-oriented, person-centered mental health care, yet the practice is not always transferred to the routine psychiatric visit. Supporting the practice at the system level, beyond the interactions of consumers and medication prescribers, is needed for successful adoption of shared decision-making. CommonGround is a systemic approach, intended to be part of a larger integration of shared decision-making tools and practices at the system level. We discuss the organizational components that CommonGround uses to facilitate shared decision-making, and we present a fidelity scale to assess how well the system is being implemented. PMID:28090194

  9. Professional competencies in health promotion and public health: what is common and what is specific? Review of the European debate and perspectives for professional development.

    PubMed

    Mereu, Alessandra; Sotgiu, Alessandra; Buja, Alessandra; Casuccio, Alessandra; Cecconi, Rosaria; Fabiani, Leila; Guberti, Emilia; Lorini, Chiara; Minelli, Liliana; Pocetta, Giancarlo; Contu, Paolo

    2015-01-01

    According to the Nairobi Call to Action, the growth of practitioners' skills can be favoured by setting accreditation standards and by reorienting professional competencies of current and future health workers. This will make it possible to develop a critical mass of competent practitioners, foster training, and increase visibility of the professional field. Through a review of the literature, the authors offer an overview of competency-based strategies for professional development in health promotion. The main research questions discussed were as follows: Is there a shared definition of public health?; Is there a shared definition of health promotion?; Who are the main stakeholders for public health and health promotion in Europe?; What is the meaning of professional competencies in education and practice for public health and health promotion?; Is there a shared system of professional core competencies in public health and health promotion?;What is common and what is specific between the two systems of professional competencies?; Is it useful and feasible to create specific strategies of professional development for public health and health promotion? A transformative use of competencies makes it possible to inform students, professionals, employers, and political decision-makers about what is expected from a specific profession and its values.

  10. Factors associated with bed and room sharing in Chinese school-aged children.

    PubMed

    Li, S; Jin, X; Yan, C; Wu, S; Jiang, F; Shen, X

    2009-03-01

    Co-sleeping (bed or room sharing) has potential implications for children's development. Previous studies showed that co-sleeping was more prevalent in non-Western countries than in Western countries, which demonstrated that co-sleeping was marked with ethnic and socio-cultural background characteristics. The purpose of this study was to survey the prevalence of bed and room sharing and to examine related factors among school-aged children in an Asian country - China. A cross-sectional questionnaire survey was conducted in 10 districts of Shanghai, China from November to December 2005. A total of 4108 elementary school children, 49.2% boys and 50.8% girls with a mean age of 8.79 years, participated. Parent-administered questionnaires were used to collect information about children's sleeping arrangements and socio-demographic characteristics. The prevalence of routine bed sharing, room sharing and sleeping alone in Chinese school-aged children was 21.0%, 19.1% and 47.7%, respectively. Bed and room sharing didn't show significant gender difference but gradually decreased with increasing age. Multivariate logistic regression identified those factors associated with bed and room sharing: younger age, large family, children without their own bedroom and parents' approval of a co-sleeping arrangement. Co-sleeping arrangement was a common practice in Chinese school-aged children. Associated factors were characterized by intrinsic socio-cultural values and socio-economic status in China.

  11. Examining age-related shared variance between face cognition, vision, and self-reported physical health: a test of the common cause hypothesis for social cognition

    PubMed Central

    Olderbak, Sally; Hildebrandt, Andrea; Wilhelm, Oliver

    2015-01-01

    The shared decline in cognitive abilities, sensory functions (e.g., vision and hearing), and physical health with increasing age is well documented with some research attributing this shared age-related decline to a single common cause (e.g., aging brain). We evaluate the extent to which the common cause hypothesis predicts associations between vision and physical health with social cognition abilities specifically face perception and face memory. Based on a sample of 443 adults (17–88 years old), we test a series of structural equation models, including Multiple Indicator Multiple Cause (MIMIC) models, and estimate the extent to which vision and self-reported physical health are related to face perception and face memory through a common factor, before and after controlling for their fluid cognitive component and the linear effects of age. Results suggest significant shared variance amongst these constructs, with a common factor explaining some, but not all, of the shared age-related variance. Also, we found that the relations of face perception, but not face memory, with vision and physical health could be completely explained by fluid cognition. Overall, results suggest that a single common cause explains most, but not all age-related shared variance with domain specific aging mechanisms evident. PMID:26321998

  12. Comparison of professional values of Taiwanese and United States nursing students.

    PubMed

    Alfred, Danita; Yarbrough, Susan; Martin, Pam; Mink, Janice; Lin, Yu-Hua; Wang, Liching S

    2013-12-01

    Globalization is a part of modern life. Sharing a common set of professional nursing values is critical in this global environment. The purpose of this research was to examine the professional values of nursing students from two distinct cultural perspectives. Nurse educators in Taiwan partnered with nurse educators in the United States to compare professional values of their respective graduating nursing students. The American Nurses Association Code of Ethics served as the philosophical framework for this examination. The convenience sample comprised 94 Taiwanese students and 168 US students. Both groups reported high scores on an overall measure of values. They did differ substantially on the relative importance of individual items related to advocacy, competence, education, self-evaluation, professional advancement, and professional associations. Global implications for the collaborative practice of nurses from different cultures working together can be improved by first recognizing and then attending to these differences in value priorities.

  13. Choosing to Decline: Finding Common Ground through the Perspective of Shared Decision Making.

    PubMed

    Megregian, Michele; Nieuwenhuijze, Marianne

    2018-05-18

    Respectful communication is a key component of any clinical relationship. Shared decision making is the process of collaboration that occurs between a health care provider and patient in order to make health care decisions based upon the best available evidence and the individual's preferences. A midwife and woman (and her support persons) engage together to make health care decisions, using respectful communication that is based upon the best available evidence and the woman's preferences, values, and goals. Supporting a woman's autonomy, however, can be particularly challenging in maternity care when recommended treatments or interventions are declined. In the past, the real or perceived increased risk to a woman's health or that of her fetus as a result of that choice has occasionally resulted in coercion. Through the process of shared decision making, the woman's autonomy may be supported, including the choice to decline interventions. The case presented here demonstrates how a shared decision-making framework can support the health care provider-patient relationship in the context of informed refusal. © 2018 by the American College of Nurse-Midwives.

  14. Use of the Blue Button Online Tool for Sharing Health Information: Qualitative Interviews With Patients and Providers.

    PubMed

    Klein, Dawn M; Fix, Gemmae M; Hogan, Timothy P; Simon, Steven R; Nazi, Kim M; Turvey, Carolyn L

    2015-08-18

    Information sharing between providers is critical for care coordination, especially in health systems such as the United States Department of Veterans Affairs (VA), where many patients also receive care from other health care organizations. Patients can facilitate this sharing by using the Blue Button, an online tool that promotes patients' ability to view, print, and download their health records. The aim of this study was to characterize (1) patients' use of Blue Button, an online information-sharing tool in VA's patient portal, My HealtheVet, (2) information-sharing practices between VA and non-VA providers, and (3) how providers and patients use a printed Blue Button report during a clinical visit. Semistructured qualitative interviews were conducted with 34 VA patients, 10 VA providers, and 9 non-VA providers. Interviews focused on patients' use of Blue Button, information-sharing practices between VA and non-VA providers, and how patients and providers use a printed Blue Button report during a clinical visit. Qualitative themes were identified through iterative rounds of coding starting with an a priori schema based on technology adoption theory. Information sharing between VA and non-VA providers relied primarily on the patient. Patients most commonly used Blue Button to access and share VA laboratory results. Providers recognized the need for improved information sharing, valued the Blue Button printout, and expressed interest in a way to share information electronically across settings. Consumer-oriented technologies such as Blue Button can facilitate patients sharing health information with providers in other health care systems; however, more education is needed to inform patients of this use to facilitate care coordination. Additional research is needed to explore how personal health record documents, such as Blue Button reports, can be easily shared and incorporated into the clinical workflow of providers.

  15. Opinions of general practitioners about psychotherapy and their relationships with mental health professionals in the management of major depression: A qualitative survey

    PubMed Central

    Dumesnil, Hélène; Apostolidis, Thémis; Verger, Pierre

    2018-01-01

    Background French general practitioners (GPs) refer their patients with major depression to psychiatrists or for psychotherapy at particularly low rates. Objectives This qualitative study aims to explore general practitioners' (GP) opinions about psychotherapy, their relationships with mental health professionals, their perceptions of their role and that of psychiatrists in treating depression, and the relations between these factors and the GPs' strategies for managing depression. Methods In 2011, in-depth interviews based on a semi-structured interview guide were conducted with 32 GPs practicing in southeastern France. Verbatim transcripts were examined by analyzing their thematic content. Results We identified three profiles of physicians according to their opinions and practices about treatment strategies for depression: pro-pharmacological treatment, pro-psychotherapy and those with mixed practices. Most participants considered their relationships with psychiatrists unsatisfactory, would like more and better collaboration with them and shared the same concept of management in general practice. This concept was based both on the values and principles of practice shared by GPs and on their strong differentiation of their management practices from those of psychiatrists, Conclusion Several attitudes and values common to GPs might contribute to their low rate of referrals for psychotherapy in France: strong occupational identity, substantial variations in GPs' attitudes and practices regarding depression treatment strategies, representations sometimes unfavorable toward psychiatrists. Actions to develop a common culture and improve cooperation between GPs and psychiatrists are essential. They include systems of collaborative care and the development of interdisciplinary training common to GPs and psychiatrists practicing in the same area. PMID:29385155

  16. 78 FR 7835 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing of Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... at $145 per share would carry a total deliverable value of $145,000, and the strike price would be... Jumbo option strike price of $145 was trading at $146 per share, the intrinsic $1 per share value would... Shares Deliverable Upon Exercise 100 shares........ 1,000 shares Strike Price if underlying is 45 45 $45...

  17. [Proportional abundance of culicidae in the urban ecosystem of Havana City].

    PubMed

    Marquetti, M C; González, D; Aguilera, L; Navarro, A

    1999-01-01

    Proportional abundance of the four most common mosquito species was determined in six types of breeding places located in Plaza de la Revolución municipality, City of Havana from 1993-1996. Culex quinquifasciatus exhibited values over 0.60 except in tyres and larval traps in 1993 and 1994 whereas Aedes mediovittatus showed similar values in low tanks and artificial reservoirs in 1994 (0.43 and 0.56 respectively). It was also observed that this species prefers larval traps. Aedes aegypti and Culex migripaplpus had the lowest abundance values (0.01). These results allowed us to state that there is a sort of shared use by these species of those reservoirs where they breed and that Culex quinquefasciatus is the predominant one.

  18. Eliciting the Intension of Drug Value Sets – Principles and Quality Assurance Applications

    PubMed Central

    Bahr, Nathan J.; Nelson, Scott D.; Winnenburg, Rainer; Bodenreider, Olivier

    2018-01-01

    Value sets (VSs) used in electronic clinical quality measures are lists of codes from standard terminologies (“extensional” VSs), whose purpose (“intension”) is not always explicitly stated. We elicited the intension for the 09/01/2014 release of extensional medication value sets by comparison to drug classes from the October 2014 release of RxClass. Value sets matched drug classes if they shared common ingredients, as evidenced by Jaccard similarity score. We elicited the intension of 80 extensional value sets. The average Jaccard similarity was 0.65 for single classes and 0.80 for combination classes, with 34% (27/80) of the value sets having high similarity scores. Manual review by a pharmacist indicated 51% (41/80) of the drug classes selected as the best mapping for a value set matched the intension reflected in that value set name. This approach has the potential for facilitating the development and maintenance of medication value sets. PMID:29295218

  19. Joint analysis of binary and quantitative traits with data sharing and outcome-dependent sampling.

    PubMed

    Zheng, Gang; Wu, Colin O; Kwak, Minjung; Jiang, Wenhua; Joo, Jungnam; Lima, Joao A C

    2012-04-01

    We study the analysis of a joint association between a genetic marker with both binary (case-control) and quantitative (continuous) traits, where the quantitative trait values are only available for the cases due to data sharing and outcome-dependent sampling. Data sharing becomes common in genetic association studies, and the outcome-dependent sampling is the consequence of data sharing, under which a phenotype of interest is not measured for some subgroup. The trend test (or Pearson's test) and F-test are often, respectively, used to analyze the binary and quantitative traits. Because of the outcome-dependent sampling, the usual F-test can be applied using the subgroup with the observed quantitative traits. We propose a modified F-test by also incorporating the genotype frequencies of the subgroup whose traits are not observed. Further, a combination of this modified F-test and Pearson's test is proposed by Fisher's combination of their P-values as a joint analysis. Because of the correlation of the two analyses, we propose to use a Gamma (scaled chi-squared) distribution to fit the asymptotic null distribution for the joint analysis. The proposed modified F-test and the joint analysis can also be applied to test single trait association (either binary or quantitative trait). Through simulations, we identify the situations under which the proposed tests are more powerful than the existing ones. Application to a real dataset of rheumatoid arthritis is presented. © 2012 Wiley Periodicals, Inc.

  20. Publications in academic medical centers: technology-facilitated culture clash.

    PubMed

    Berner, Eta S

    2014-05-01

    Academic culture has a set of norms, expectations, and values that are sometimes tacit and sometimes very explicit. In medical school and other health professions educational settings, probably the most common norm includes placing a high value on peer-reviewed research publications, which are seen as the major evidence of scholarly productivity. Other features of academic culture include encouraging junior faculty and graduate students to share their research results at professional conferences and lecturing with slides as a major way to convey information. Major values that faculty share with journal editors include responsible conduct of research and proper attribution of others' words and ideas. Medical school faculty also value technology and are often quick to embrace technological advances that can assist them in their teaching and research. This article addresses the effects of technology on three aspects of academic culture: education, presentations at professional meetings, and research publications.The technologies discussed include online instruction, dissemination of conference proceedings on the Internet, plagiarism-detection software, and new technologies deployed by the National Center for Biotechnology Information, the home of PubMed. The author describes how the ease of deploying new technologies without faculty changing their norms and behavior in the areas of teaching and research can lead to conflicts of values among key stakeholders in the academic medical community, including faculty, journal editors, and professional associations. The implications of these conflicts and strategies for managing them are discussed.

  1. The public goods game with a new form of shared reward

    NASA Astrophysics Data System (ADS)

    Zhang, Chunyan; Chen, Zengqiang

    2016-10-01

    Altruistic contribution to a common good evenly enjoyed by all group members is hard to explain because of the greater benefits obtained by a defector than a cooperator. A variety of mechanisms have been proposed to resolve the collective dilemma over the years, including rewards for altruism. An underrated and easily ignored phenomenon is that the altruistic behaviors of cooperators not only directly enhance the benefits of their game opponents, but also indirectly produce good influences to other allied members in their surroundings (e.g. relatives or friends). Here we propose a shared reward, in the form of extensive benefits, to extend the traditional definition of the public goods game. Mathematical analysis using the Moran process helps us to obtain the fixation probability for one ‘mutant’ cooperator to invade and dominate the whole defecting population. Results suggest that a tunable parameter exists, above a certain critical value of which natural selection favors cooperation over defection. In addition, analytical results with replicator dynamics show that this critical value influencing the evolution of altruism is closely correlated with the population size, the gaming group size and the synergy factor of the public goods game. These results, based on an extended notion of shared reward and extensive benefits, are expected to provide novel explanations for the emergence of altruistic behaviors.

  2. Twelve myths about shared decision making.

    PubMed

    Légaré, France; Thompson-Leduc, Philippe

    2014-09-01

    As shared decision makes increasing headway in healthcare policy, it is under more scrutiny. We sought to identify and dispel the most prevalent myths about shared decision making. In 20 years in the shared decision making field one of the author has repeatedly heard mention of the same barriers to scaling up shared decision making across the healthcare spectrum. We conducted a selective literature review relating to shared decision making to further investigate these commonly perceived barriers and to seek evidence supporting their existence or not. Beliefs about barriers to scaling up shared decision making represent a wide range of historical, cultural, financial and scientific concerns. We found little evidence to support twelve of the most common beliefs about barriers to scaling up shared decision making, and indeed found evidence to the contrary. Our selective review of the literature suggests that twelve of the most commonly perceived barriers to scaling up shared decision making across the healthcare spectrum should be termed myths as they can be dispelled by evidence. Our review confirms that the current debate about shared decision making must not deter policy makers and clinicians from pursuing its scaling up across the healthcare continuum. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  3. Grouping and binding in visual short-term memory.

    PubMed

    Quinlan, Philip T; Cohen, Dale J

    2012-09-01

    Findings of 2 experiments are reported that challenge the current understanding of visual short-term memory (VSTM). In both experiments, a single study display, containing 6 colored shapes, was presented briefly and then probed with a single colored shape. At stake is how VSTM retains a record of different objects that share common features: In the 1st experiment, 2 study items sometimes shared a common feature (either a shape or a color). The data revealed a color sharing effect, in which memory was much better for items that shared a common color than for items that did not. The 2nd experiment showed that the size of the color sharing effect depended on whether a single pair of items shared a common color or whether 2 pairs of items were so defined-memory for all items improved when 2 color groups were presented. In explaining performance, an account is advanced in which items compete for a fixed number of slots, but then memory recall for any given stored item is prone to error. A critical assumption is that items that share a common color are stored together in a slot as a chunk. The evidence provides further support for the idea that principles of perceptual organization may determine the manner in which items are stored in VSTM. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  4. "Our Shared Values" in Singapore: A Confucian Perspective

    ERIC Educational Resources Information Center

    Tan, Charlene

    2012-01-01

    In this essay Charlene Tan offers a philosophical analysis of the Singapore state's vision of shared citizenship by examining it from a Confucian perspective. The state's vision, known formally as "Our Shared Values," consists of communitarian values that reflect the official ideology of multiculturalism. This initiative included a White…

  5. Military Health System: Sustained Senior Leadership Needed to Fully Develop Plans for Achieving Cost Savings

    DTIC Science & Technology

    2014-02-26

    left its existing structure in place, approving instead a shared - services directorate to consolidate common MHS functions (e.g., shared information...has seven main goals: (1) consolidate functions ( shared services ) common to DoD, (2) deliver more-integrated health care in areas with more than one

  6. The complementary niches of anthropocentric and biocentric conservationists.

    PubMed

    Hunter, Malcolm L; Redford, Kent H; Lindenmayer, David B

    2014-06-01

    A divergence of values has become apparent in recent debates between conservationists who focus on ecosystem services that can improve human well-being and those who focus on avoiding the extinction of species. These divergent points of view fall along a continuum from anthropocentric to biocentric values, but most conservationists are relatively closer to each other than to the ends of the spectrum. We have some concerns with both positions but emphasize that conservation for both people and all other species will be most effective if conservationists focus on articulating the values they all share, being respectful of divergent values, and collaborating on common interests. The conservation arena is large enough to accommodate many people and organizations whose diverse values lead them to different niches that can, with good will and foresight, be far more complementary than competitive. © 2014 Society for Conservation Biology.

  7. Is a share buyback right for your company?

    PubMed

    Pettit, J

    2001-04-01

    Contrary to popular wisdom, buybacks don't create value by raising earnings per share. But they do indeed create value, and in two very different ways. First, a buyback sends signals about the company's prospects to the market--hopefully, that prospects are so good that the best investment managers can make right now is in their own company. But investors won't see it that way if other, negative, signals are coming from the company, and it's rarely a good idea for companies in high-growth industries, where investors expect that money to be spent pursuing new opportunities. Second, when financed as a debt issue, a buyback is essentially an exchange of equity for debt, conferring the traditional benefits of leverage--a tax shield and a discipline for managers. For such a buyback to make sense, a company would need to have taxable profits in need of shielding, of course, and be able to predict its future cash flows fairly accurately. Justin Pettit has found that managers routinely underestimate how many shares they need to buy to send a credible signal to the markets, and he offers a way to calculate that number. He also goes through the iterative steps involved in working out how many shares must be purchased to reach a target level of debt. Then he takes a look at the advantages and disadvantages of the three most common ways that companies make the actual purchases--open-market purchases, fixed-price tender offers, and auction-based tender offers. When a company's performance is lagging, a share buyback can look attractive. Unfortunately, a buyback can backfire--unless executives understand why, when, and how to use this powerful and risky tool.

  8. Blood pressure and cerebral white matter share common genetic factors in Mexican Americans.

    PubMed

    Kochunov, Peter; Glahn, David C; Lancaster, Jack; Winkler, Anderson; Karlsgodt, Kathrin; Olvera, Rene L; Curran, Joanna E; Carless, Melanie A; Dyer, Thomas D; Almasy, Laura; Duggirala, Ravi; Fox, Peter T; Blangero, John

    2011-02-01

    Elevated arterial pulse pressure and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially attributable to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican Americans. The patterns of whole-brain and regional genetic overlap between BP and fractional anisotropy were interpreted in the context the pulse-wave encephalopathy theory. We also tested whether regional pattern in genetic pleiotropy is modulated by the phylogeny of WM development. BP and high-resolution (1.7 × 1.7 × 3 mm; 55 directions) diffusion tensor imaging data were analyzed for 332 (202 females; mean age 47.9 ± 13.3 years) members of the San Antonio Family Heart Study. Bivariate genetic correlation analysis was used to calculate the genetic overlap between several BP measurements (pulse pressure, systolic BP, and diastolic BP) and fractional anisotropy (whole-brain and regional values). Intersubject variance in pulse pressure and systolic BP exhibited a significant genetic overlap with variance in whole-brain fractional anisotropy values, sharing 36% and 22% of genetic variance, respectively. Regionally, shared genetic variance was significantly influenced by rates of WM development (r=-0.75; P=0.01). The pattern of genetic overlap between BP and WM integrity was generally in agreement with the pulse-wave encephalopathy theory. Our study provides evidence that a set of pleiotropically acting genetic factors jointly influence phenotypic variation in BP and WM integrity. The magnitude of this overlap appears to be influenced by phylogeny of WM development, suggesting a possible role for genotype-by-age interactions.

  9. Blood Pressure and Cerebral White Matter Share Common Genetic Factors in Mexican-Americans

    PubMed Central

    Kochunov, Peter; Glahn, David C; Lancaster, Jack; Winkler, Anderson; Karlsgodt, Kathrin; Olvera, Rene L; Curran, Joanna E; Carless, Melanie A; Dyer, Thomas D; Almasy, Laura; Duggirala, Ravi; Fox, Peter T; Blangero, John

    2010-01-01

    Elevated arterial pulse pressure (PP) and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially due to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy (FA) of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican-Americans. The patterns of whole-brain and regional genetic overlap between BP and FA were interpreted in the context the pulse-wave encephalopathy (PWE) theory. We also tested whether regional pattern in genetic pleiotropy is modulated by the phylogeny of WM development. BP and high-resolution (1.7×1.7×3mm, 55 directions) diffusion tensor imaging (DTI) data were analyzed for 332 (202 females; mean age=47.9±13.3years) members of the San Antonio Family Heart Study. Bivariate genetic correlation analysis was used to calculate the genetic overlap between several BP measurements [PP, systolic (SBP) and diastolic (DBP)] and FA (whole-brain and regional values). Intersubject variance in PP and SBP exhibited a significant genetic overlap with variance in whole-brain FA values, sharing 36% and 22% of genetic variance, respectively. Regionally, shared genetic variance was significantly influenced by rates of WM development (r=−.75, p=0.01). The pattern of genetic overlap between BP and WM integrity was generally in-agreement with the PWE theory. Our study provides evidence that a set of pleiotropically acting genetic factors jointly influence phenotypic variation in BP and WM integrity. The magnitude of this overlap appears to be influenced by phylogeny of WM development suggesting a possible role for genotype-by-age interactions. PMID:21135356

  10. Vibrio chromosomes share common history.

    PubMed

    Kirkup, Benjamin C; Chang, LeeAnn; Chang, Sarah; Gevers, Dirk; Polz, Martin F

    2010-05-10

    While most gamma proteobacteria have a single circular chromosome, Vibrionales have two circular chromosomes. Horizontal gene transfer is common among Vibrios, and in light of this genetic mobility, it is an open question to what extent the two chromosomes themselves share a common history since their formation. Single copy genes from each chromosome (142 genes from chromosome I and 42 genes from chromosome II) were identified from 19 sequenced Vibrionales genomes and their phylogenetic comparison suggests consistent phylogenies for each chromosome. Additionally, study of the gene organization and phylogeny of the respective origins of replication confirmed the shared history. Thus, while elements within the chromosomes may have experienced significant genetic mobility, the backbones share a common history. This allows conclusions based on multilocus sequence analysis (MLSA) for one chromosome to be applied equally to both chromosomes.

  11. The genomic similarities with linguistic difference: a study among the Oraon and Munda tribes of the Ranchi district, Jharkhand, India.

    PubMed

    Mondal, Prakash Ranjan; Saksena, Deepti; Sachdeva, Mohinder Pal; Murry, Benrithung; Meitei, Khangembam Somibabu; Samtani, Ratika; Saraswathy, Kallur Nava

    2011-06-01

    The present study was conducted on two tribal communities, the Oraon and Munda, inhabiting the Ranchi district of Jharkhand state, India. The study was designed to elucidate genetic similarity, if any, shared between these tribes as they belong to the common Proto-Australoid stock but bear different linguistic affiliations. For this, a total of 98 intravenous blood samples (48 Oraon and 50 Munda) were collected from unrelated individuals of either sex up to first cousins, with their prior informed written consent. The DNA was extracted and studied for a total of 20 autosomal markers, including 7 Alu Indels, 3 DRD2 TaqI sites, 3 β-globin sites, and 7 restriction site polymorphisms. All the 20 studied molecular markers were found to be polymorphic in both the tribal population groups and showed similarities with respect to allele frequencies, with a low coefficient of gene differentiation (G(ST)) value. Moreover, sharing and distribution patterns of haplotypes of the β-globin gene cluster suggest that the Oraon and Munda share a common ancestry. However, small differences between them with reference to the linkage disequilibrium (LD) pattern indicate that the Munda might have emerged as a result of admixture between Proto-Australoids and Austro-Asiatic-speaking Mongoloids as supported by the principal co-ordinate analysis, wherein the Munda are closely placed with the Dravidian-speaking Proto-Australoid tribes of India. A common genetic substratum (Proto-Australoid stock) of the Oraon and Munda was evident in the present study, although these tribes are distinct linguistically.

  12. 10 CFR 603.525 - Value and reasonableness of the recipient's cost sharing contribution.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Value and reasonableness of the recipient's cost sharing contribution. 603.525 Section 603.525 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Cost Sharing § 603.525 Value and reasonableness of the...

  13. Philanthropy and Beyond: Creating Shared Value to Promote Well-Being for Individuals in Their Communities.

    PubMed

    Kottke, Thomas E; Pronk, Nico; Zinkel, Andrew R; Isham, George J

    2017-01-01

    Health care organizations can magnify the impact of their community service and other philanthropic activities by implementing programs that create shared value. By definition, shared value is created when an initiative generates benefit for the sponsoring organization while also generating societal and community benefit. Because the programs generate benefit for the sponsoring organizations, the magnitude of any particular initiative is limited only by the market for the benefit and not the resources that are available for philanthropy.In this article we use three initiatives in sectors other than health care to illustrate the concept of shared value. We also present examples of five types of shared value programs that are sponsored by health care organizations: telehealth, worksite health promotion, school-based health centers, green and healthy housing, and clean and green health services. On the basis of the innovativeness of health care organizations that have already implemented programs that create shared value, we conclude that the opportunities for all health care organizations to create positive impact for individuals and communities through similar programs is large, and the limits have yet to be defined.

  14. Surveying hospital network structure in New York State: how are they structured?

    PubMed

    Nauenberg, E; Brewer, C S

    2000-01-01

    We determine the most common network structures in New York state. The taxonomy employed uses three structural dimensions: integration, complexity, and risk-sharing between organizations. Based on a survey conducted in 1996, the most common type of network (26.4 percent) had medium levels of integration, medium or high levels of complexity, and some risk-sharing. Also common were networks with low levels of integration, low levels of complexity, and no risk-sharing (22.1 percent).

  15. Developing a data sharing community for spinal cord injury research.

    PubMed

    Callahan, Alison; Anderson, Kim D; Beattie, Michael S; Bixby, John L; Ferguson, Adam R; Fouad, Karim; Jakeman, Lyn B; Nielson, Jessica L; Popovich, Phillip G; Schwab, Jan M; Lemmon, Vance P

    2017-09-01

    The rapid growth in data sharing presents new opportunities across the spectrum of biomedical research. Global efforts are underway to develop practical guidance for implementation of data sharing and open data resources. These include the recent recommendation of 'FAIR Data Principles', which assert that if data is to have broad scientific value, then digital representations of that data should be Findable, Accessible, Interoperable and Reusable (FAIR). The spinal cord injury (SCI) research field has a long history of collaborative initiatives that include sharing of preclinical research models and outcome measures. In addition, new tools and resources are being developed by the SCI research community to enhance opportunities for data sharing and access. With this in mind, the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) hosted a workshop on October 5-6, 2016 in Bethesda, MD, in collaboration with the Open Data Commons for Spinal Cord Injury (ODC-SCI) titled "Preclinical SCI Data: Creating a FAIR Share Community". Workshop invitees were nominated by the workshop steering committee (co-chairs: ARF and VPL; members: AC, KDA, MSB, KF, LBJ, PGP, JMS), to bring together junior and senior level experts including preclinical and basic SCI researchers from academia and industry, data science and bioinformatics experts, investigators with expertise in other neurological disease fields, clinical researchers, members of the SCI community, and program staff representing federal and private funding agencies. The workshop and ODC-SCI efforts were sponsored by the International Spinal Research Trust (ISRT), the Rick Hansen Institute, Wings for Life, the Craig H. Neilsen Foundation and NINDS. The number of attendees was limited to ensure active participation and feedback in small groups. The goals were to examine the current landscape for data sharing in SCI research and provide a path to its future. Below are highlights from the workshop, including perspectives on the value of data sharing in SCI research, workshop participant perspectives and concerns, descriptions of existing resources and actionable directions for further engaging the SCI research community in a model that may be applicable to many other areas of neuroscience. This manuscript is intended to share these initial findings with the broader research community, and to provide talking points for continued feedback from the SCI field, as it continues to move forward in the age of data sharing. Copyright © 2017. Published by Elsevier Inc.

  16. What does social justice require for the public's health? Public health ethics and policy imperatives.

    PubMed

    Gostin, Lawrence O; Powers, Madison

    2006-01-01

    Justice is so central to the mission of public health that it has been described as the field's core value. This account of justice stresses the fair disbursement of common advantages and the sharing of common burdens. It captures the twin moral impulses that animate public health: to advance human well-being by improving health and to do so particularly by focusing on the needs of the most disadvantaged. This Commentary explores how social justice sheds light on major ongoing controversies in the field, and it provides examples of the kinds of policies that public health agencies, guided by a robust conception of justice, would adopt.

  17. Exploring the Common Dynamics of Homologous Proteins. Application to the Globin Family

    PubMed Central

    Maguid, Sandra; Fernandez-Alberti, Sebastian; Ferrelli, Leticia; Echave, Julian

    2005-01-01

    We present a procedure to explore the global dynamics shared between members of the same protein family. The method allows the comparison of patterns of vibrational motion obtained by Gaussian network model analysis. After the identification of collective coordinates that were conserved during evolution, we quantify the common dynamics within a family. Representative vectors that describe these dynamics are defined using a singular value decomposition approach. As a test case, the globin heme-binding family is considered. The two lowest normal modes are shown to be conserved within this family. Our results encourage the development of models for protein evolution that take into account the conservation of dynamical features. PMID:15749782

  18. Drivers Of Health As A Shared Value: Mindset, Expectations, Sense Of Community, And Civic Engagement.

    PubMed

    Chandra, Anita; Miller, Carolyn E; Acosta, Joie D; Weilant, Sarah; Trujillo, Matthew; Plough, Alonzo

    2016-11-01

    Making health a shared value is central to building a culture of health, a new action framework intended to spur faster progress toward equitable health outcomes in the United States. Unlike in other US social movements, such as the environmental and civil rights movements, the necessary understanding of shared values has not yet been achieved for health. Discussions about values regarding health have primarily focused on health care instead of health or well-being. These discussions have not progressed to a clear focus on prioritizing values on health instead of simply health care. The evidence base for understanding health as a shared value is only now emerging. Making health a shared value is the first of four Action Areas in the Robert Wood Johnson Foundation's Culture of Health Action Framework. We assert that the achievement of this shared understanding of health as a cultural value will be enhanced through action in specific drivers: mindset and expectations, sense of community, and civic engagement. Building on a literature review and stakeholder engagement, this article examines the evidence base for these drivers and identifies where policy and research actions are needed to advance positive change on population health and well-being outcomes. Project HOPE—The People-to-People Health Foundation, Inc.

  19. A design of strategic alliance based on value chain of surveying and mapping enterprises in China

    NASA Astrophysics Data System (ADS)

    Duan, Hong; Huang, Xianfeng

    2007-06-01

    In this paper, we use value chain and strategic alliance theories to analyzing the surveying and mapping Industry and enterprises. The value chain of surveying and mapping enterprises is highly-contacted but split by administrative interference, the enterprises are common small scale. According to the above things, we consider that establishing a nonequity- Holding strategic alliance based on value chain is an available way, it can not only let the enterprises share the superior resources in different sectors of the whole value chain each other but avoid offending the interests of related administrative departments, by this way, the surveying and mapping enterprises gain development respectively and totally. Then, we give the method to building up the strategic alliance model through parting the value chain and the using advantage of companies in different value chain sectors. Finally, we analyze the internal rule of strategic alliance and prove it is a suitable way to realize the development of surveying and mapping enterprises through game theory.

  20. Human dignity in concept and practice

    USGS Publications Warehouse

    Mattson, D.J.; Clark, S.G.

    2011-01-01

    Dignity seems to be something that virtually all people want. It is a seminal expression of the human experience that gains authority through the convergent demands of people worldwide. Even so, the human dignity concept is in unhelpful disarray. Dignity is variously viewed as an antecedent, a consequence, a value, a principle, and an experience, from philosophical, legal, pragmatic, psychological, behavioral, and cultural perspectives. We ask which if any of these human dignity concepts will likely serve our global common interests best, as both common ground and policy diagnostic? We examine four broad themes: dignity as (1) a metaphysical justification for human rights and duties, (2) virtuous comportment or behavior, (3) a perspective of "other," and (4) a subjective experience of the individual, contingent on a broad and equitable sharing of values. We recommend viewing dignity as a commonwealth of individually assessed well-being, shaped by relationships with others, affected by the physical world, and framed in terms of values. Viewed this way, the idea of dignity accommodates the priorities of both individualistic and communitarian cultures. Conceiving of human dignity as a commonwealth of subjectively experienced value production and enjoyment has many practical policy implications. ?? 2011 Springer Science+Business Media, LLC (outside the USA).

  1. Negotiating Commercial Interests in Biospecimens.

    PubMed

    Roberts, Jessica L

    2017-03-01

    Proposed changes to the Common Rule would require publicly funded researchers to disclose whether a subject's biospecimens could be used for commercial profit and whether the subject will share in those proceeds. Disclosing commercial interests will inform research participants that their tissue may have commercial value, a possibility that those individuals might not have previously considered. The proposed changes may then provide people with an opportunity to negotiate commercial rights in their biospecimens despite the well-accepted legal precedent that individuals maintain no interests in their excised tissue.

  2. Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.

    PubMed

    Binda, Claudia; Wang, Jin; Pisani, Leonardo; Caccia, Carla; Carotti, Angelo; Salvati, Patricia; Edmondson, Dale E; Mattevi, Andrea

    2007-11-15

    Structures of human monoamine oxidase B (MAO B) in complex with safinamide and two coumarin derivatives, all sharing a common benzyloxy substituent, were determined by X-ray crystallography. These compounds competitively inhibit MAO B with Ki values in the 0.1-0.5 microM range that are 30-700-fold lower than those observed with MAO A. The inhibitors bind noncovalently to MAO B, occupying both the entrance and the substrate cavities and showing a similarly oriented benzyloxy substituent.

  3. Shared Values, Particular Values, and Education for a Multicultural Society.

    ERIC Educational Resources Information Center

    Singh, Basil R.

    1995-01-01

    Within the framework of liberal democratic values are shared (universal) values and particular cultural values. Social harmony depends on integrating these two sets of values. The role of multicultural education is to stress cultural development rather than cultural maintenance while adhering to principles of inclusion. (SK)

  4. Individual responsibility as ground for priority setting in shared decision-making.

    PubMed

    Sandman, Lars; Gustavsson, Erik; Munthe, Christian

    2016-10-01

    Given healthcare resource constraints, voices are being raised to hold patients responsible for their health choices. In parallel, there is a growing trend towards shared decision-making, aiming to empower patients and give them more control over healthcare decisions. More power and control over decisions is usually taken to mean more responsibility for them. The trend of shared decision-making would therefore seem to strengthen the case for invoking individual responsibility in the healthcare priority setting. To analyse whether the implementation of shared decision-making would strengthen the argument for invoking individual responsibility in the healthcare priority setting using normative analysis. Shared decision-making does not constitute an independent argument in favour of employing individual responsibility since these notions rest on different underlying values. However, if a health system employs shared decision-making, individual responsibility may be used to limit resource implications of accommodating patient preferences outside professional standards and goals. If a healthcare system employs individual responsibility, high level dynamic shared decision-making implying a joint deliberation resulting in a decision where both parties are willing to revise initial standpoints may disarm common objections to the applicability of individual responsibility by virtue of making patients more likely to exercise adequate control of their own actions. However, if communication strategies applied in the shared decision-making are misaligned to the patient's initial capacities, arguments against individual responsibility might, on the other hand, gain strength. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. The composition, heating value and renewable share of the energy content of mixed municipal solid waste in Finland.

    PubMed

    Horttanainen, M; Teirasvuo, N; Kapustina, V; Hupponen, M; Luoranen, M

    2013-12-01

    For the estimation of greenhouse gas emissions from waste incineration it is essential to know the share of the renewable energy content of the combusted waste. The composition and heating value information is generally available, but the renewable energy share or heating values of different fractions of waste have rarely been determined. In this study, data from Finnish studies concerning the composition and energy content of mixed MSW were collected, new experimental data on the compositions, heating values and renewable share of energy were presented and the results were compared to the estimations concluded from earlier international studies. In the town of Lappeenranta in south-eastern Finland, the share of renewable energy ranged between 25% and 34% in the energy content tests implemented for two sample trucks. The heating values of the waste and fractions of plastic waste were high in the samples compared to the earlier studies in Finland. These high values were caused by good source separation and led to a low share of renewable energy content in the waste. The results showed that in mixed municipal solid waste the renewable share of the energy content can be significantly lower than the general assumptions (50-60%) when the source separation of organic waste, paper and cardboard is carried out successfully. The number of samples was however small for making extensive conclusions on the results concerning the heating values and renewable share of energy and additional research is needed for this purpose. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Knowledge Sharing among University Students Facilitated with a Creative Commons Licensing Mechanism: A Case Study in a Programming Course

    ERIC Educational Resources Information Center

    Liu, Chen-Chung; Lin, Chia-Ching; Chang, Chun-Yi; Chao, Po-Yao

    2014-01-01

    Creative Commons (CC) mechanism has been suggested as a potential means to foster a reliable environment for online knowledge sharing activity. This study investigates the role of the CC mechanism in supporting knowledge sharing among a group of university students studying programming from the perspectives of social cognitive and social capital…

  7. Sharing Rare Attitudes Attracts.

    PubMed

    Alves, Hans

    2018-04-01

    People like others who share their attitudes. Online dating platforms as well as other social media platforms regularly rely on the social bonding power of their users' shared attitudes. However, little is known about moderating variables. In the present work, I argue that sharing rare compared with sharing common attitudes should evoke stronger interpersonal attraction among people. In five studies, I tested this prediction for the case of shared interests from different domains. I found converging evidence that people's rare compared with their common interests are especially potent to elicit interpersonal attraction. I discuss the current framework's theoretical implications for impression formation and impression management as well as its practical implications for improving online dating services.

  8. A Review of Shared Decision-Making and Patient Decision Aids in Radiation Oncology.

    PubMed

    Woodhouse, Kristina Demas; Tremont, Katie; Vachani, Anil; Schapira, Marilyn M; Vapiwala, Neha; Simone, Charles B; Berman, Abigail T

    2017-06-01

    Cancer treatment decisions are complex and may be challenging for patients, as multiple treatment options can often be reasonably considered. As a result, decisional support tools have been developed to assist patients in the decision-making process. A commonly used intervention to facilitate shared decision-making is a decision aid, which provides evidence-based outcomes information and guides patients towards choosing the treatment option that best aligns with their preferences and values. To ensure high quality, systematic frameworks and standards have been proposed for the development of an optimal aid for decision making. Studies have examined the impact of these tools on facilitating treatment decisions and improving decision-related outcomes. In radiation oncology, randomized controlled trials have demonstrated that decision aids have the potential to improve patient outcomes, including increased knowledge about treatment options and decreased decisional conflict with decision-making. This article provides an overview of the shared-decision making process and summarizes the development, validation, and implementation of decision aids as patient educational tools in radiation oncology. Finally, this article reviews the findings from decision aid studies in radiation oncology and offers various strategies to effectively implement shared decision-making into clinical practice.

  9. Reducible or irreducible? Mathematical reasoning and the ontological method.

    PubMed

    Fisher, William P

    2010-01-01

    Science is often described as nothing but the practice of measurement. This perspective follows from longstanding respect for the roles mathematics and quantification have played as media through which alternative hypotheses are evaluated and experience becomes better managed. Many figures in the history of science and psychology have contributed to what has been called the "quantitative imperative," the demand that fields of study employ number and mathematics even when they do not constitute the language in which investigators think together. But what makes an area of study scientific is, of course, not the mere use of number, but communities of investigators who share common mathematical languages for exchanging quantitative and quantitative value. Such languages require rigorous theoretical underpinning, a basis in data sufficient to the task, and instruments traceable to reference standard quantitative metrics. The values shared and exchanged by such communities typically involve the application of mathematical models that specify the sufficient and invariant relationships necessary for rigorous theorizing and instrument equating. The mathematical metaphysics of science are explored with the aim of connecting principles of quantitative measurement with the structures of sufficient reason.

  10. The composition, heating value and renewable share of the energy content of mixed municipal solid waste in Finland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horttanainen, M., E-mail: mika.horttanainen@lut.fi; Teirasvuo, N.; Kapustina, V.

    Highlights: • New experimental data of mixed MSW properties in a Finnish case region. • The share of renewable energy of mixed MSW. • The results were compared with earlier international studies. • The average share of renewable energy was 30% and the average LHVar 19 MJ/kg. • Well operating source separation decreases the renewable energy content of MSW. - Abstract: For the estimation of greenhouse gas emissions from waste incineration it is essential to know the share of the renewable energy content of the combusted waste. The composition and heating value information is generally available, but the renewable energymore » share or heating values of different fractions of waste have rarely been determined. In this study, data from Finnish studies concerning the composition and energy content of mixed MSW were collected, new experimental data on the compositions, heating values and renewable share of energy were presented and the results were compared to the estimations concluded from earlier international studies. In the town of Lappeenranta in south-eastern Finland, the share of renewable energy ranged between 25% and 34% in the energy content tests implemented for two sample trucks. The heating values of the waste and fractions of plastic waste were high in the samples compared to the earlier studies in Finland. These high values were caused by good source separation and led to a low share of renewable energy content in the waste. The results showed that in mixed municipal solid waste the renewable share of the energy content can be significantly lower than the general assumptions (50–60%) when the source separation of organic waste, paper and cardboard is carried out successfully. The number of samples was however small for making extensive conclusions on the results concerning the heating values and renewable share of energy and additional research is needed for this purpose.« less

  11. Philanthropy and Beyond: Creating Shared Value to Promote Well-Being for Individuals in Their Communities

    PubMed Central

    Kottke, Thomas E; Pronk, Nico; Zinkel, Andrew R; Isham, George J

    2017-01-01

    Health care organizations can magnify the impact of their community service and other philanthropic activities by implementing programs that create shared value. By definition, shared value is created when an initiative generates benefit for the sponsoring organization while also generating societal and community benefit. Because the programs generate benefit for the sponsoring organizations, the magnitude of any particular initiative is limited only by the market for the benefit and not the resources that are available for philanthropy. In this article we use three initiatives in sectors other than health care to illustrate the concept of shared value. We also present examples of five types of shared value programs that are sponsored by health care organizations: telehealth, worksite health promotion, school-based health centers, green and healthy housing, and clean and green health services. On the basis of the innovativeness of health care organizations that have already implemented programs that create shared value, we conclude that the opportunities for all health care organizations to create positive impact for individuals and communities through similar programs is large, and the limits have yet to be defined. PMID:28488982

  12. Use of the Blue Button Online Tool for Sharing Health Information: Qualitative Interviews With Patients and Providers

    PubMed Central

    Fix, Gemmae M; Hogan, Timothy P; Simon, Steven R; Nazi, Kim M; Turvey, Carolyn L

    2015-01-01

    Background Information sharing between providers is critical for care coordination, especially in health systems such as the United States Department of Veterans Affairs (VA), where many patients also receive care from other health care organizations. Patients can facilitate this sharing by using the Blue Button, an online tool that promotes patients’ ability to view, print, and download their health records. Objective The aim of this study was to characterize (1) patients’ use of Blue Button, an online information-sharing tool in VA’s patient portal, My HealtheVet, (2) information-sharing practices between VA and non-VA providers, and (3) how providers and patients use a printed Blue Button report during a clinical visit. Methods Semistructured qualitative interviews were conducted with 34 VA patients, 10 VA providers, and 9 non-VA providers. Interviews focused on patients’ use of Blue Button, information-sharing practices between VA and non-VA providers, and how patients and providers use a printed Blue Button report during a clinical visit. Qualitative themes were identified through iterative rounds of coding starting with an a priori schema based on technology adoption theory. Results Information sharing between VA and non-VA providers relied primarily on the patient. Patients most commonly used Blue Button to access and share VA laboratory results. Providers recognized the need for improved information sharing, valued the Blue Button printout, and expressed interest in a way to share information electronically across settings. Conclusions Consumer-oriented technologies such as Blue Button can facilitate patients sharing health information with providers in other health care systems; however, more education is needed to inform patients of this use to facilitate care coordination. Additional research is needed to explore how personal health record documents, such as Blue Button reports, can be easily shared and incorporated into the clinical workflow of providers. PMID:26286139

  13. Using 3d Bim Model for the Value-Based Land Share Calculations

    NASA Astrophysics Data System (ADS)

    Çelik Şimşek, N.; Uzun, B.

    2017-11-01

    According to the Turkish condominium ownership system, 3D physical buildings and its condominium units are registered to the condominium ownership books via 2D survey plans. Currently, 2D representations of the 3D physical objects, causes inaccurate and deficient implementations for the determination of the land shares. Condominium ownership and easement right are established with a clear indication of land shares (condominium ownership law, article no. 3). So, the land share of each condominium unit have to be determined including the value differences among the condominium units. However the main problem is that, land share has often been determined with area based over the project before construction of the building. The objective of this study is proposing a new approach in terms of value-based land share calculations of the condominium units that subject to condominium ownership. So, the current approaches and its failure that have taken into account in determining the land shares are examined. And factors that affect the values of the condominium units are determined according to the legal decisions. This study shows that 3D BIM models can provide important approaches for the valuation problems in the determination of the land shares.

  14. Integrating cultural community psychology: activity settings and the shared meanings of intersubjectivity.

    PubMed

    O'Donnell, Clifford R; Tharp, Roland G

    2012-03-01

    Cultural and community psychology share a common emphasis on context, yet their leading journals rarely cite each other's articles. Greater integration of the concepts of culture and community within and across their disciplines would enrich and facilitate the viability of cultural community psychology. The contextual theory of activity settings is proposed as one means to integrate the concepts of culture and community in cultural community psychology. Through shared activities, participants develop common experiences that affect their psychological being, including their cognitions, emotions, and behavioral development. The psychological result of these experiences is intersubjectivity. Culture is defined as the shared meanings that people develop through their common historic, linguistic, social, economic, and political experiences. The shared meanings of culture arise through the intersubjectivity developed in activity settings. Cultural community psychology presents formidable epistemological challenges, but overcoming these challenges could contribute to the transformation and advancement of community psychology.

  15. The Non-Problem of the Other Minds: A Neurodevelopmental Perspective on Shared Intentionality

    ERIC Educational Resources Information Center

    Colle, Livia; Becchio, Cristina; Bara, Bruno G.

    2008-01-01

    In this paper, we combine neurological and developmental evidences in order to differentiate between two levels of sharing: dyadic sharing, virtually present from birth and depending on the activation of shared representation, and triadic sharing, requiring that agents not only share a common representation, but also represent complementary…

  16. 26 CFR 1.883-2T - Treatment of publicly-traded corporations (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shareholders, as defined in § 1.883-4(b)(1); (B) The total percentage of the value of the shares owned... outstanding shares in that class of stock as of the close of the taxable year, and the value of each class of stock in relation to the total value of all the corporation's shares outstanding as of the close of the...

  17. 17 CFR 270.30b1-6T - Weekly portfolio report for certain money market funds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...; (I) The amortized cost value; and (J) In the case of a tax-exempt security, whether there is a demand... the fund's stable net asset value per share or stable price per share pursuant to § 270.2a-7(c)(1...) Market-based NAV means a money market fund's net asset value per share calculated using available market...

  18. Growing our capacity within AGU to better connect and engage with new and novel partners

    NASA Astrophysics Data System (ADS)

    Vano, J. A.

    2017-12-01

    It is easy to give talks at AGU about the value of science. It is much harder, yet critical, to share the value of science with non-scientists. Yet through conversations and ultimately through partnerships with the communities and decision makers the science aims to serve, the value of the science can be elevated and research transformed to be more actionable. Throughout AGU, there is a growing recognition that we can do this better. This growing movement comes from all corners of the Union, as evidenced by increasing abstracts on the topic, and is bringing to light efforts with a common thread of researchers collaborating with practitioners to design, conduct, apply, and share research in ways that connect more closely to society's needs. This year, a team of AGU members came together to plan a series of Science to Action sessions, workshops, networking events, and more (see http://thrivingearthexchange.org/fall-meeting-2017 for updates). This presentation will provide an overview of these Science to Action activities, how they connect with current AGU resources, and, based on past discussions and a survey of participants, what future directions and resources would provide the biggest benefits to continue to improve AGU's capacity to foster more effective partnerships. Audience participation on ideas for future directions will be encouraged.

  19. Young Children's Understanding of Cultural Common Ground

    ERIC Educational Resources Information Center

    Liebal, Kristin; Carpenter, Malinda; Tomasello, Michael

    2013-01-01

    Human social interaction depends on individuals identifying the common ground they have with others, based both on personally shared experiences and on cultural common ground that all members of the group share. We introduced 3- and 5-year-old children to a culturally well-known object and a novel object. An experimenter then entered and asked,…

  20. Stakeholders' views on data sharing in multicenter studies.

    PubMed

    Mazor, Kathleen M; Richards, Allison; Gallagher, Mia; Arterburn, David E; Raebel, Marsha A; Nowell, W Benjamin; Curtis, Jeffrey R; Paolino, Andrea R; Toh, Sengwee

    2017-09-01

    To understand stakeholders' views on data sharing in multicenter comparative effectiveness research studies and the value of privacy-protecting methods. Semistructured interviews with five US stakeholder groups. We completed 11 interviews, involving patients (n = 15), researchers (n = 10), Institutional Review Board and regulatory staff (n = 3), multicenter research governance experts (n = 2) and healthcare system leaders (n = 4). Perceptions of the benefits and value of research were the strongest influences toward data sharing; cost and security risks were primary influences against sharing. Privacy-protecting methods that share summary-level data were acknowledged as being appealing, but there were concerns about increased cost and potential loss of research validity. Stakeholders were open to data sharing in multicenter studies that offer value and minimize security risks.

  1. Information Sharing and Collaboration Business Plan

    DTIC Science & Technology

    2006-03-30

    for information sharing The proposed environment will need a common definition of terms and dictionaries of competing terms where common definitions...a lexicon, a monolingual on-line handbook, and a thesaurus and ontology of abbreviations, acronyms, and terminology. (ISCO 2005, 18

  2. The Value of Sharing Information: A Neural Account of Information Transmission.

    PubMed

    Baek, Elisa C; Scholz, Christin; O'Donnell, Matthew Brook; Falk, Emily B

    2017-07-01

    Humans routinely share information with one another. What drives this behavior? We used neuroimaging to test an account of information selection and sharing that emphasizes inherent reward in self-reflection and connecting with other people. Participants underwent functional MRI while they considered personally reading and sharing New York Times articles. Activity in neural regions involved in positive valuation, self-related processing, and taking the perspective of others was significantly associated with decisions to select and share articles, and scaled with preferences to do so. Activity in all three sets of regions was greater when participants considered sharing articles with other people rather than selecting articles to read themselves. The findings suggest that people may consider value not only to themselves but also to others even when selecting news articles to consume personally. Further, sharing heightens activity in these pathways, in line with our proposal that humans derive value from self-reflection and connecting to others via sharing.

  3. Couples' cultural values, shared parenting, and family emotional climate within Mexican American families.

    PubMed

    Sotomayor-Peterson, Marcela; Figueredo, Aurelio J; Christensen, Donna H; Taylor, Angela R

    2012-06-01

    This study tested a model of shared parenting as its centerpiece that incorporates cultural values as predictors and family emotional climate as the outcome variable of interest. We aimed to assess the predictive power of the Mexican cultural values of familismo and simpatia over couples' shared parenting practices. We anticipated that higher levels of shared parenting would predict family emotional climate. The participants were 61 Mexican American, low income couples, with at least one child between 3 and 4 years of age, recruited from a home-based Head Start program. The predictive model demonstrated excellent goodness of fit, supporting the hypothesis that a positive emotional climate within the family is fostered when Mexican American couples practice a sufficient level of shared parenting. Empirical evidence was previously scarce on this proposition. The findings also provide evidence for the role of cultural values, highlighting the importance of family solidarity and avoidance of confrontation as a pathway to shared parenting within Mexican American couples. © FPI, Inc.

  4. Ethical sharing of health data in online platforms - which values should be considered?

    PubMed

    Riso, Brígida; Tupasela, Aaro; Vears, Danya F; Felzmann, Heike; Cockbain, Julian; Loi, Michele; Kongsholm, Nana C H; Zullo, Silvia; Rakic, Vojin

    2017-08-21

    Intensified and extensive data production and data storage are characteristics of contemporary western societies. Health data sharing is increasing with the growth of Information and Communication Technology (ICT) platforms devoted to the collection of personal health and genomic data. However, the sensitive and personal nature of health data poses ethical challenges when data is disclosed and shared even if for scientific research purposes.With this in mind, the Science and Values Working Group of the COST Action CHIP ME 'Citizen's Health through public-private Initiatives: Public health, Market and Ethical perspectives' (IS 1303) identified six core values they considered to be essential for the ethical sharing of health data using ICT platforms. We believe that using this ethical framework will promote respectful scientific practices in order to maintain individuals' trust in research.We use these values to analyse five ICT platforms and explore how emerging data sharing platforms are reconfiguring the data sharing experience from a range of perspectives. We discuss which types of values, rights and responsibilities they entail and enshrine within their philosophy or outlook on what it means to share personal health information. Through this discussion we address issues of the design and the development process of personal health data and patient-oriented infrastructures, as well as new forms of technologically-mediated empowerment.

  5. Communication: Is a coarse-grained model for water sufficient to compute Kapitza conductance on non-polar surfaces?

    PubMed

    Ardham, Vikram Reddy; Leroy, Frédéric

    2017-10-21

    Coarse-grained models have increasingly been used in large-scale particle-based simulations. However, due to their lack of degrees of freedom, it is a priori unlikely that they straightforwardly represent thermal properties with the same accuracy as their atomistic counterparts. We take a first step in addressing the impact of liquid coarse-graining on interfacial heat conduction by showing that an atomistic and a coarse-grained model of water may yield similar values of the Kapitza conductance on few-layer graphene with interactions ranging from hydrophobic to mildly hydrophilic. By design the water models employed yield similar liquid layer structures on the graphene surfaces. Moreover, they share common vibration properties close to the surfaces and thus couple with the vibrations of graphene in a similar way. These common properties explain why they yield similar Kapitza conductance values despite their bulk thermal conductivity differing by more than a factor of two.

  6. Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators.

    PubMed

    Clarke, Luka A; Botelho, Hugo M; Sousa, Lisete; Falcao, Andre O; Amaral, Margarida D

    2015-11-01

    A meta-analysis of 13 independent microarray data sets was performed and gene expression profiles from cystic fibrosis (CF), similar disorders (COPD: chronic obstructive pulmonary disease, IPF: idiopathic pulmonary fibrosis, asthma), environmental conditions (smoking, epithelial injury), related cellular processes (epithelial differentiation/regeneration), and non-respiratory "control" conditions (schizophrenia, dieting), were compared. Similarity among differentially expressed (DE) gene lists was assessed using a permutation test, and a clustergram was constructed, identifying common gene markers. Global gene expression values were standardized using a novel approach, revealing that similarities between independent data sets run deeper than shared DE genes. Correlation of gene expression values identified putative gene regulators of the CF transmembrane conductance regulator (CFTR) gene, of potential therapeutic significance. Our study provides a novel perspective on CF epithelial gene expression in the context of other lung disorders and conditions, and highlights the contribution of differentiation/EMT and injury to gene signatures of respiratory disease. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Citizenship Education and Human Rights in Sites of Ethnic Conflict: Toward Critical Pedagogies of Compassion and Shared Fate

    ERIC Educational Resources Information Center

    Zembylas, Michalinos

    2012-01-01

    The present essay discusses the value of citizenship as shared fate in sites of ethnic conflict and analyzes its implications for citizenship education in light of three issues: first, the requirements of affective relationality in the notion of citizenship-as-shared fate; second, the tensions between the values of human rights and shared fate in…

  8. Community-based shared values as a 'Heart-ware' driver for integrated watershed management: Japan-Malaysia policy learning perspective

    NASA Astrophysics Data System (ADS)

    Mohamad, Zeeda Fatimah; Nasaruddin, Affan; Abd Kadir, Siti Norasiah; Musa, Mohd Noor; Ong, Benjamin; Sakai, Nobumitsu

    2015-11-01

    This paper explores the case for using ;community-based shared values; as a potential driver for the ;Heartware; aspects of governance in Integrated Watershed Management (IWM) - from a Japan-Malaysia policy learning perspective. This policy approach was originally inspired by the Japanese experience, and the paper investigates whether a similar strategy can be adapted in the Malaysian context-based on a qualitative exploratory case study of a local downstream watershed community. The community-based shared values are categorized into six functional values that can be placed on a watershed: industry, ecosystem, lifestyle, landscape, water resource and spirituality. The study confirmed the availability of a range of community-based shared values in each category that are promising to drive the heartware for integrated watershed management in the local Malaysian context. However, most of these shared values are either declining in its appreciation or nostalgic in nature. The paper ends with findings on key differences and similarities between the Malaysian and Japanese contexts, and concludes with lessons for international transfer of IWM heartware policy strategies between the two countries.

  9. How "moral" are the principles of biomedical ethics?--a cross-domain evaluation of the common morality hypothesis.

    PubMed

    Christen, Markus; Ineichen, Christian; Tanner, Carmen

    2014-06-17

    The principles of biomedical ethics - autonomy, non-maleficence, beneficence, and justice - are of paradigmatic importance for framing ethical problems in medicine and for teaching ethics to medical students and professionals. In order to underline this significance, Tom L. Beauchamp and James F. Childress base the principles in the common morality, i.e. they claim that the principles represent basic moral values shared by all persons committed to morality and are thus grounded in human moral psychology. We empirically investigated the relationship of the principles to other moral and non-moral values that provide orientations in medicine. By way of comparison, we performed a similar analysis for the business & finance domain. We evaluated the perceived degree of "morality" of 14 values relevant to medicine (n1 = 317, students and professionals) and 14 values relevant to business & finance (n2 = 247, students and professionals). Ratings were made along four dimensions intended to characterize different aspects of morality. We found that compared to other values, the principles-related values received lower ratings across several dimensions that characterize morality. By interpreting our finding using a clustering and a network analysis approach, we suggest that the principles can be understood as "bridge values" that are connected both to moral and non-moral aspects of ethical dilemmas in medicine. We also found that the social domain (medicine vs. business & finance) influences the degree of perceived morality of values. Our results are in conflict with the common morality hypothesis of Beauchamp and Childress, which would imply domain-independent high morality ratings of the principles. Our findings support the suggestions by other scholars that the principles of biomedical ethics serve primarily as instruments in deliberated justifications, but lack grounding in a universal "common morality". We propose that the specific manner in which the principles are taught and discussed in medicine - namely by referring to conflicts requiring a balancing of principles - may partly explain why the degree of perceived "morality" of the principles is lower compared to other moral values.

  10. Defense Health Care: Applying Key Management Practices Should Help Achieve Efficiencies within the Military Health System

    DTIC Science & Technology

    2012-04-01

    5. Realign the TRICARE Management Activity and establish a Joint Military Health Service Directorate to consolidate shared services and common...Directorate to consolidate shared services and common functions Realign TRICARE Management Activity and establish a TRICARE Health Plan Agency to...Uniformed Services University of the Health Sciences, (2) TRICARE health plan, (3) Health Management Support, and (4) Shared Services division

  11. Research review: the shared environment as a key source of variability in child and adolescent psychopathology.

    PubMed

    Burt, S Alexandra

    2014-04-01

    Behavioral genetic research has historically concluded that the more important environmental influences were nonshared or result in differences between siblings, whereas environmental influences that create similarities between siblings (referred to as shared environmental influences) were indistinguishable from zero. Recent theoretical and meta-analytic work {Burt. Psychological Bulletin [135 (2009) 608]} has challenged this conclusion as it relates to child and adolescent psychopathology, however, arguing that the shared environment is a moderate, persistent, and identifiable source of individual differences in such outcomes prior to adulthood. The current review seeks to bolster research on the shared environment by highlighting both the logistic advantages inherent in studies of the shared environment, as well as the use of nontraditional but still genetically informed research designs to study shared environmental influences. Although often moderate in magnitude prior to adulthood and free of unsystematic measurement error, shared environmental influences are nevertheless likely to have been underestimated in prior research. Moreover, the shared environment is likely to include proximal effects of the family, as well as the effects of more distal environmental contexts such as neighborhood and school. These risk and protective factors could influence the child either as main effects or as moderators of genetic influence (i.e. gene-environment interactions). Finally, because the absence of genetic relatedness in an otherwise nonindependent dataset also qualifies as 'genetically informed', studies of the shared environment are amenable to the use of novel and non-traditional designs (with appropriate controls for selection). The shared environment makes important contributions to most forms of child and adolescent psychopathology. Empirical examinations of the shared environment would thus be of real and critical value for understanding the development and persistence of common mental health issues prior to adulthood. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.

  12. Ethnic diversity and value sharing: A longitudinal social network perspective on interactive group processes.

    PubMed

    Meeussen, Loes; Agneessens, Filip; Delvaux, Ellen; Phalet, Karen

    2018-04-01

    People often collaborate in groups that are increasingly diverse. As research predominantly investigated effects of diversity, the processes behind these effects remain understudied. We follow recent research that shows creating shared values is important for group functioning but seems hindered in high diversity groups - and use longitudinal social network analyses to study two interpersonal processes behind value sharing: creating relations between members or 'social bonding' (network tie formation and homophily) and sharing values - potentially through these relationships - or 'social norming' (network convergence and influence). We investigate these processes in small interactive groups with low and high ethnic diversity as they collaborate over time. In both low and high diversity groups, members showed social bonding and this creation of relations between members was not organized along ethnic lines. Low diversity groups also showed social norming: Members adjusted their relational values to others they liked and achievement values converged regardless of liking. In high diversity groups, however, there was no evidence for social norming. Thus, ethnic diversity seems to especially affect processes of social norming in groups, suggesting that targeted interventions should focus on facilitating social norming to stimulate value sharing in high diversity groups. © 2018 The British Psychological Society.

  13. Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

    PubMed Central

    Tonomura, Noriko; Elvers, Ingegerd; Thomas, Rachael; Megquier, Kate; Turner-Maier, Jason; Howald, Cedric; Sarver, Aaron L.; Swofford, Ross; Frantz, Aric M.; Ito, Daisuke; Mauceli, Evan; Arendt, Maja; Noh, Hyun Ji; Koltookian, Michele; Biagi, Tara; Fryc, Sarah; Williams, Christina; Avery, Anne C.; Kim, Jong-Hyuk; Barber, Lisa; Burgess, Kristine; Lander, Eric S.; Karlsson, Elinor K.; Azuma, Chieko

    2015-01-01

    Dogs, with their breed-determined limited genetic background, are great models of human disease including cancer. Canine B-cell lymphoma and hemangiosarcoma are both malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angiosarcoma, respectively. Golden retrievers in the US show significantly elevated lifetime risk for both B-cell lymphoma (6%) and hemangiosarcoma (20%). We conducted genome-wide association studies for hemangiosarcoma and B-cell lymphoma, identifying two shared predisposing loci. The two associated loci are located on chromosome 5, and together contribute ~20% of the risk of developing these cancers. Genome-wide p-values for the top SNP of each locus are 4.6×10-7 and 2.7×10-6, respectively. Whole genome resequencing of nine cases and controls followed by genotyping and detailed analysis identified three shared and one B-cell lymphoma specific risk haplotypes within the two loci, but no coding changes were associated with the risk haplotypes. Gene expression analysis of B-cell lymphoma tumors revealed that carrying the risk haplotypes at the first locus is associated with down-regulation of several nearby genes including the proximal gene TRPC6, a transient receptor Ca2+-channel involved in T-cell activation, among other functions. The shared risk haplotype in the second locus overlaps the vesicle transport and release gene STX8. Carrying the shared risk haplotype is associated with gene expression changes of 100 genes enriched for pathways involved in immune cell activation. Thus, the predisposing germ-line mutations in B-cell lymphoma and hemangiosarcoma appear to be regulatory, and affect pathways involved in T-cell mediated immune response in the tumor. This suggests that the interaction between the immune system and malignant cells plays a common role in the tumorigenesis of these relatively different cancers. PMID:25642983

  14. Takayasu arteritis and ulcerative colitis: high rate of co-occurrence and genetic overlap.

    PubMed

    Terao, Chikashi; Matsumura, Takayoshi; Yoshifuji, Hajime; Kirino, Yohei; Maejima, Yasuhiro; Nakaoka, Yoshikazu; Takahashi, Meiko; Amiya, Eisuke; Tamura, Natsuko; Nakajima, Toshiki; Origuchi, Tomoki; Horita, Tetsuya; Matsukura, Mitsuru; Kochi, Yuta; Ogimoto, Akiyoshi; Yamamoto, Motohisa; Takahashi, Hiroki; Nakayamada, Shingo; Saito, Kazuyoshi; Wada, Yoko; Narita, Ichiei; Kawaguchi, Yasushi; Yamanaka, Hisashi; Ohmura, Koichiro; Atsumi, Tatsuya; Tanemoto, Kazuo; Miyata, Tetsuro; Kuwana, Masataka; Komuro, Issei; Tabara, Yasuharu; Ueda, Atsuhisa; Isobe, Mitsuaki; Mimori, Tsuneyo; Matsuda, Fumihiko

    2015-05-01

    Takayasu arteritis (TAK) is a systemic vasculitis affecting large arteries and large branches of the aorta. Ulcerative colitis (UC) is a prevalent autoimmune colitis. Since TAK and UC share HLA-B*52:01 and IL12B as genetic determinants, and since there are case reports of the co-occurrence of these diseases, we hypothesized that UC is a common complication of TAK. We undertook this study to perform a large-scale analysis of TAK, both to evaluate the prevalence of concurrent cases of TAK and UC and to identify and estimate susceptibility genes shared between the 2 diseases. We analyzed a total of 470 consecutive patients with TAK from 14 institutions. We characterized patients with TAK and UC by analyzing clinical manifestations and genetic components. Genetic overlapping of TAK and UC was evaluated with the use of UC susceptibility single-nucleotide polymorphisms by comparing risk directions and effect sizes between susceptibility to the 2 diseases. Thirty of 470 patients with TAK had UC (6.4% [95% confidence interval 4.3-9.0]). This percentage was strikingly higher than that expected from the prevalence of UC in Japan. Patients with TAK complicated with UC developed TAK at an earlier stage of life (P = 0.0070) and showed significant enrichment of HLA-B*52:01 compared to TAK patients without UC (P = 1.0 × 10(-5) ) (odds ratio 12.14 [95% confidence interval 2.96-107.23]). The 110 non-HLA markers of susceptibility to UC significantly displayed common risk directions with susceptibility to TAK (P = 0.0054) and showed significant departure of permutation P values from expected P values (P < 1.0 × 10(-10) ). UC is a major complication of TAK. These 2 diseases share a significant proportion of their genetic background, and HLA-B*52:01 may play a central role in their co-occurrence. © 2015, American College of Rheumatology.

  15. Serial interpolation for secure membership testing and matching in a secret-split archive

    DOEpatents

    Kroeger, Thomas M.; Benson, Thomas R.

    2016-12-06

    The various technologies presented herein relate to analyzing a plurality of shares stored at a plurality of repositories to determine whether a secret from which the shares were formed matches a term in a query. A threshold number of shares are formed with a generating polynomial operating on the secret. A process of serially interpolating the threshold number of shares can be conducted whereby a contribution of a first share is determined, a contribution of a second share is determined while seeded with the contribution of the first share, etc. A value of a final share in the threshold number of shares can be determined and compared with the search term. In the event of the value of the final share and the search term matching, the search term matches the secret in the file from which the shares are formed.

  16. The reasons young children give to peers when explaining their judgments of moral and conventional rules.

    PubMed

    Mammen, Maria; Köymen, Bahar; Tomasello, Michael

    2018-02-01

    Moral justifications work, when they do, by invoking values that are shared in the common ground of the interlocutors. We asked 3- and 5-year-old peer dyads (N = 144) to identify and punish norm transgressors. In the moral condition, the transgressor violated a moral norm (e.g., by stealing); in the social rules condition, she/he violated a context-specific rule (e.g., by placing a yellow toy in a green box, instead of a yellow box). Children in both age groups justified their punishment in the social rules condition mostly by referring to the rule (e.g., "He must put yellow toys in the yellow box"). In contrast, in the moral condition they mostly justified their punishment by simply referring to the observed fact (e.g., "He stole"), seeing no need to state the norm involved (e.g., "He must not steal"), presumably because they assumed this as part of their moral common ground with their partner. These results suggest that preschoolers assume certain common ground moral values with their peers and use these in formulating explicit moral judgments and justifications. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. Chaotic Dynamics and Application of LCR Oscillators Sharing Common Nonlinearity

    NASA Astrophysics Data System (ADS)

    Jeevarekha, A.; Paul Asir, M.; Philominathan, P.

    2016-06-01

    This paper addresses the problem of sharing common nonlinearity among nonautonomous and autonomous oscillators. By choosing a suitable common nonlinear element with the driving point characteristics capable of bringing out chaotic motion in a combined system, we obtain identical chaotic states. The dynamics of the coupled system is explored through numerical and experimental studies. Employing the concept of common nonlinearity, a simple chaotic communication system is modeled and its performance is verified through Multisim simulation.

  18. Introduction: The Humanities and the Sciences.

    PubMed

    Bod, Rens; Kursell, Julia

    2015-06-01

    The humanities and the sciences have a strongly connected history, yet their histories continue to be written separately. Although the scope of the history of science has undergone a tremendous broadening during the past few decades, scholars of the history of the humanities and the history of science still seem to belong to two separate cultures that have endured through the past century. This Focus section explores what common ground would enable a study of the histories of the humanities and the sciences to investigate their shared epistemic objects, virtues, values, methods, and practices.

  19. Climatic Warmth and National Wealth: Some Culture-Level Determinants of National Character Stereotypes

    PubMed Central

    McCrae, Robert R.; Terracciano, Antonio; Realo, Anu; Allik, Jüri

    2009-01-01

    National character stereotypes are widely shared, but do not reflect assessed levels of personality traits. In this article we present data illustrating the divergence of stereotypes and assessed personality traits in north and south Italy, test hypotheses about the associations of temperature and national wealth with national character stereotypes in 49 cultures, and explore possible links to national values and beliefs. Results suggest that warmth and wealth are common determinants of national stereotypes, but that there are also idiosyncratic influences on the perceptions of individual nations. PMID:20046546

  20. Climatic Warmth and National Wealth: Some Culture-Level Determinants of National Character Stereotypes.

    PubMed

    McCrae, Robert R; Terracciano, Antonio; Realo, Anu; Allik, Jüri

    2007-12-01

    National character stereotypes are widely shared, but do not reflect assessed levels of personality traits. In this article we present data illustrating the divergence of stereotypes and assessed personality traits in north and south Italy, test hypotheses about the associations of temperature and national wealth with national character stereotypes in 49 cultures, and explore possible links to national values and beliefs. Results suggest that warmth and wealth are common determinants of national stereotypes, but that there are also idiosyncratic influences on the perceptions of individual nations.

  1. All inequality is not equal: children correct inequalities using resource value.

    PubMed

    Shaw, Alex; Olson, Kristina R

    2013-01-01

    Fairness concerns guide children's judgments about how to share resources with others. However, it is unclear from past research if children take extant inequalities or the value of resources involved in an inequality into account when sharing with others; these questions are the focus of the current studies. In all experiments, children saw an inequality between two recipients-one had two more resources than another. What varied between conditions was the value of the resources that the child could subsequently distribute. When the resources were equal in value to those involved in the original inequality, children corrected the previous inequality by giving two resources to the child with fewer resources (Experiment 1). However, as the value of the resources increased relative to those initially shared by the experimenter, children were more likely to distribute the two high value resources equally between the two recipients, presumably to minimize the overall inequality in value (Experiments 1 and 2). We found that children specifically use value, not just size, when trying to equalize outcomes (Experiment 3) and further found that children focus on the relative rather than absolute value of the resources they share-when the experimenter had unequally distributed the same high value resource that the child would later share, children corrected the previous inequality by giving two high value resources to the person who had received fewer high value resources. These results illustrate that children attempt to correct past inequalities and try to maintain equality not just in the count of resources but also by using the value of resources.

  2. Comparative analysis of student self-reflections on course projects

    NASA Astrophysics Data System (ADS)

    Pomales-García, Cristina; Cortés Barreto, Kenneth

    2014-11-01

    This study presents the skills, experiences, and values identified in project self-reflections of 161 undergraduate engineering students. Self-reflections from two different engineering design courses, which provide experiences in project-based learning (PBL), are analysed through the content analysis methodology. Results show that 'application', 'true life', 'satisfaction', and 'communication' are the common keywords shared in the reflections. Multiple hypothesis tests to identify differences between courses, project types, years, and gender suggest that there are no significant differences between experiences, skills, and values self-reported by students who completed either a case study or an industry project. Based on research findings, recommendations will be provided to enhance the engineering curriculum based on PBL experiences to support the development of relevant professional skills and experiences.

  3. Genetic and environmental contributions to body mass index: comparative analysis of monozygotic twins, dizygotic twins and same-age unrelated siblings.

    PubMed

    Segal, N L; Feng, R; McGuire, S A; Allison, D B; Miller, S

    2009-01-01

    Earlier studies have established that a substantial percentage of variance in obesity-related phenotypes is explained by genetic components. However, only one study has used both virtual twins (VTs) and biological twins and was able to simultaneously estimate additive genetic, non-additive genetic, shared environmental and unshared environmental components in body mass index (BMI). Our current goal was to re-estimate four components of variance in BMI, applying a more rigorous model to biological and virtual multiples with additional data. Virtual multiples share the same family environment, offering unique opportunities to estimate common environmental influence on phenotypes that cannot be separated from the non-additive genetic component using only biological multiples. Data included 929 individuals from 164 monozygotic twin pairs, 156 dizygotic twin pairs, five triplet sets, one quadruplet set, 128 VT pairs, two virtual triplet sets and two virtual quadruplet sets. Virtual multiples consist of one biological child (or twins or triplets) plus one same-aged adoptee who are all raised together since infancy. We estimated the additive genetic, non-additive genetic, shared environmental and unshared random components in BMI using a linear mixed model. The analysis was adjusted for age, age(2), age(3), height, height(2), height(3), gender and race. Both non-additive genetic and common environmental contributions were significant in our model (P-values<0.0001). No significant additive genetic contribution was found. In all, 63.6% (95% confidence interval (CI) 51.8-75.3%) of the total variance of BMI was explained by a non-additive genetic component, 25.7% (95% CI 13.8-37.5%) by a common environmental component and the remaining 10.7% by an unshared component. Our results suggest that genetic components play an essential role in BMI and that common environmental factors such as diet or exercise also affect BMI. This conclusion is consistent with our earlier study using a smaller sample and shows the utility of virtual multiples for separating non-additive genetic variance from common environmental variance.

  4. The Effect of Shared Information on Pilot/Controller Situation Awareness and Re-Route Negotiation

    NASA Technical Reports Server (NTRS)

    Farley, Todd C.; Hansman, R. John; Endsley, Mica R.; Amonlirdviman, Keith; Vigeant-Langlois, Laurence

    1998-01-01

    The effect of shared information is assessed in terms of pilot/controller negotiation and shared situation awareness. Pilot goals and situation awareness requirements are developed and compared against those of air traffic controllers to identify areas of common and competing interest. A part-task simulator experiment is described which probes pilot/controller interaction in areas where common information has the potential to lead to contention, as identified in the comparative analysis. Preliminary results are presented which suggest that shared information can effect more collaborative interaction between pilots and air traffic controllers.

  5. Average is Over

    NASA Astrophysics Data System (ADS)

    Eliazar, Iddo

    2018-02-01

    The popular perception of statistical distributions is depicted by the iconic bell curve which comprises of a massive bulk of 'middle-class' values, and two thin tails - one of small left-wing values, and one of large right-wing values. The shape of the bell curve is unimodal, and its peak represents both the mode and the mean. Thomas Friedman, the famous New York Times columnist, recently asserted that we have entered a human era in which "Average is Over" . In this paper we present mathematical models for the phenomenon that Friedman highlighted. While the models are derived via different modeling approaches, they share a common foundation. Inherent tipping points cause the models to phase-shift from a 'normal' bell-shape statistical behavior to an 'anomalous' statistical behavior: the unimodal shape changes to an unbounded monotone shape, the mode vanishes, and the mean diverges. Hence: (i) there is an explosion of small values; (ii) large values become super-large; (iii) 'middle-class' values are wiped out, leaving an infinite rift between the small and the super large values; and (iv) "Average is Over" indeed.

  6. Channel-Based Key Generation for Encrypted Body-Worn Wireless Sensor Networks.

    PubMed

    Van Torre, Patrick

    2016-09-08

    Body-worn sensor networks are important for rescue-workers, medical and many other applications. Sensitive data are often transmitted over such a network, motivating the need for encryption. Body-worn sensor networks are deployed in conditions where the wireless communication channel varies dramatically due to fading and shadowing, which is considered a disadvantage for communication. Interestingly, these channel variations can be employed to extract a common encryption key at both sides of the link. Legitimate users share a unique physical channel and the variations thereof provide data series on both sides of the link, with highly correlated values. An eavesdropper, however, does not share this physical channel and cannot extract the same information when intercepting the signals. This paper documents a practical wearable communication system implementing channel-based key generation, including an implementation and a measurement campaign comprising indoor as well as outdoor measurements. The results provide insight into the performance of channel-based key generation in realistic practical conditions. Employing a process known as key reconciliation, error free keys are generated in all tested scenarios. The key-generation system is computationally simple and therefore compatible with the low-power micro controllers and low-data rate transmissions commonly used in wireless sensor networks.

  7. 77 FR 69693 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... collection activities at national conferences will use identical methodologies or otherwise share a common element. Similarly, the BEP's scientific studies will use very similar methodologies or share a common... conducting scientific tests. Using those methodologies, the BEP or its contracted specialists will conduct...

  8. Genomic Data Commons | Office of Cancer Genomics

    Cancer.gov

    The NCI’s Center for Cancer Genomics launches the Genomic Data Commons (GDC), a unified data sharing platform for the cancer research community. The mission of the GDC is to enable data sharing across the entire cancer research community, to ultimately support precision medicine in oncology.

  9. Multidisciplinary teams, and parents, negotiating common ground in shared-care of children with long-term conditions: A mixed methods study

    PubMed Central

    2013-01-01

    Background Limited negotiation around care decisions is believed to undermine collaborative working between parents of children with long-term conditions and professionals, but there is little evidence of how they actually negotiate their respective roles. Using chronic kidney disease as an exemplar this paper reports on a multi-method study of social interaction between multidisciplinary teams and parents as they shared clinical care. Methods Phases 1 and 2: a telephone survey mapping multidisciplinary teams’ parent-educative activities, and qualitative interviews with 112 professionals (Clinical-psychologists, Dietitians, Doctors, Nurses, Play-specialists, Pharmacists, Therapists and Social-workers) exploring their accounts of parent-teaching in the 12 British children’s kidney units. Phase 3: six ethnographic case studies in two units involving observations of professional/parent interactions during shared-care, and individual interviews. We used an analytical framework based on concepts drawn from Communities of Practice and Activity Theory. Results Professionals spoke of the challenge of explaining to each other how they are aware of parents’ understanding of clinical knowledge, and described three patterns of parent-educative activity that were common across MDTs: Engaging parents in shared practice; Knowledge exchange and role negotiation, and Promoting common ground. Over time, professionals had developed a shared repertoire of tools to support their negotiations with parents that helped them accomplish common ground during the practice of shared-care. We observed mutual engagement between professionals and parents where a common understanding of the joint enterprise of clinical caring was negotiated. Conclusions For professionals, making implicit knowledge explicit is important as it can provide them with a language through which to articulate more clearly to each other what is the basis of their intuition-based hunches about parents’ support needs, and may help them to negotiate with parents and accelerate parents’ learning about shared caring. Our methodology and results are potentially transferrable to shared management of other conditions. PMID:23835151

  10. The Geography of Recent Genetic Ancestry across Europe

    PubMed Central

    Ralph, Peter; Coop, Graham

    2013-01-01

    The recent genealogical history of human populations is a complex mosaic formed by individual migration, large-scale population movements, and other demographic events. Population genomics datasets can provide a window into this recent history, as rare traces of recent shared genetic ancestry are detectable due to long segments of shared genomic material. We make use of genomic data for 2,257 Europeans (in the Population Reference Sample [POPRES] dataset) to conduct one of the first surveys of recent genealogical ancestry over the past 3,000 years at a continental scale. We detected 1.9 million shared long genomic segments, and used the lengths of these to infer the distribution of shared ancestors across time and geography. We find that a pair of modern Europeans living in neighboring populations share around 2–12 genetic common ancestors from the last 1,500 years, and upwards of 100 genetic ancestors from the previous 1,000 years. These numbers drop off exponentially with geographic distance, but since these genetic ancestors are a tiny fraction of common genealogical ancestors, individuals from opposite ends of Europe are still expected to share millions of common genealogical ancestors over the last 1,000 years. There is also substantial regional variation in the number of shared genetic ancestors. For example, there are especially high numbers of common ancestors shared between many eastern populations that date roughly to the migration period (which includes the Slavic and Hunnic expansions into that region). Some of the lowest levels of common ancestry are seen in the Italian and Iberian peninsulas, which may indicate different effects of historical population expansions in these areas and/or more stably structured populations. Population genomic datasets have considerable power to uncover recent demographic history, and will allow a much fuller picture of the close genealogical kinship of individuals across the world. PMID:23667324

  11. Multidisciplinary teams, and parents, negotiating common ground in shared-care of children with long-term conditions: a mixed methods study.

    PubMed

    Swallow, Veronica M; Nightingale, Ruth; Williams, Julian; Lambert, Heather; Webb, Nicholas J A; Smith, Trish; Wirz, Lucy; Qizalbash, Leila; Crowther, Laura; Allen, Davina

    2013-07-08

    Limited negotiation around care decisions is believed to undermine collaborative working between parents of children with long-term conditions and professionals, but there is little evidence of how they actually negotiate their respective roles. Using chronic kidney disease as an exemplar this paper reports on a multi-method study of social interaction between multidisciplinary teams and parents as they shared clinical care. Phases 1 and 2: a telephone survey mapping multidisciplinary teams' parent-educative activities, and qualitative interviews with 112 professionals (Clinical-psychologists, Dietitians, Doctors, Nurses, Play-specialists, Pharmacists, Therapists and Social-workers) exploring their accounts of parent-teaching in the 12 British children's kidney units. Phase 3: six ethnographic case studies in two units involving observations of professional/parent interactions during shared-care, and individual interviews. We used an analytical framework based on concepts drawn from Communities of Practice and Activity Theory. Professionals spoke of the challenge of explaining to each other how they are aware of parents' understanding of clinical knowledge, and described three patterns of parent-educative activity that were common across MDTs: Engaging parents in shared practice; Knowledge exchange and role negotiation, and Promoting common ground. Over time, professionals had developed a shared repertoire of tools to support their negotiations with parents that helped them accomplish common ground during the practice of shared-care. We observed mutual engagement between professionals and parents where a common understanding of the joint enterprise of clinical caring was negotiated. For professionals, making implicit knowledge explicit is important as it can provide them with a language through which to articulate more clearly to each other what is the basis of their intuition-based hunches about parents' support needs, and may help them to negotiate with parents and accelerate parents' learning about shared caring. Our methodology and results are potentially transferrable to shared management of other conditions.

  12. How “moral” are the principles of biomedical ethics? – a cross-domain evaluation of the common morality hypothesis

    PubMed Central

    2014-01-01

    Background The principles of biomedical ethics – autonomy, non-maleficence, beneficence, and justice – are of paradigmatic importance for framing ethical problems in medicine and for teaching ethics to medical students and professionals. In order to underline this significance, Tom L. Beauchamp and James F. Childress base the principles in the common morality, i.e. they claim that the principles represent basic moral values shared by all persons committed to morality and are thus grounded in human moral psychology. We empirically investigated the relationship of the principles to other moral and non-moral values that provide orientations in medicine. By way of comparison, we performed a similar analysis for the business & finance domain. Methods We evaluated the perceived degree of “morality” of 14 values relevant to medicine (n1 = 317, students and professionals) and 14 values relevant to business & finance (n2 = 247, students and professionals). Ratings were made along four dimensions intended to characterize different aspects of morality. Results We found that compared to other values, the principles-related values received lower ratings across several dimensions that characterize morality. By interpreting our finding using a clustering and a network analysis approach, we suggest that the principles can be understood as “bridge values” that are connected both to moral and non-moral aspects of ethical dilemmas in medicine. We also found that the social domain (medicine vs. business & finance) influences the degree of perceived morality of values. Conclusions Our results are in conflict with the common morality hypothesis of Beauchamp and Childress, which would imply domain-independent high morality ratings of the principles. Our findings support the suggestions by other scholars that the principles of biomedical ethics serve primarily as instruments in deliberated justifications, but lack grounding in a universal “common morality”. We propose that the specific manner in which the principles are taught and discussed in medicine – namely by referring to conflicts requiring a balancing of principles – may partly explain why the degree of perceived “morality” of the principles is lower compared to other moral values. PMID:24938295

  13. Walking, cycling and driving to work in the English and Welsh 2011 census: trends, socio-economic patterning and relevance to travel behaviour in general.

    PubMed

    Goodman, Anna

    2013-01-01

    Increasing walking and cycling, and reducing motorised transport, are health and environmental priorities. This paper examines levels and trends in the use of different commute modes in England and Wales, both overall and with respect to small-area deprivation. It also investigates whether commute modal share can serve as a proxy for travel behaviour more generally. 23.7 million adult commuters reported their usual main mode of travelling to work in the 2011 census in England and Wales; similar data were available for 1971-2001. Indices of Multiple Deprivation were used to characterise socio-economic patterning. The National Travel Survey (2002-2010) was used to examine correlations between commute modal share and modal share of total travel time. These correlations were calculated across 150 non-overlapping populations defined by region, year band and income. Among commuters in 2011, 67.1% used private motorised transport as their usual main commute mode (-1.8 percentage-point change since 2001); 17.8% used public transport (+1.8% change); 10.9% walked (-0.1% change); and 3.1% cycled (+0.1% change). Walking and, to a marginal extent, cycling were more common among those from deprived areas, but these gradients had flattened over the previous decade to the point of having essentially disappeared for cycling. In the National Travel Survey, commute modal share and total modal share were reasonably highly correlated for private motorised transport (r = 0.94), public transport (r = 0.96), walking (r = 0.88 excluding London) and cycling (r = 0.77). England and Wales remain car-dependent, but the trends are slightly more encouraging. Unlike many health behaviours, it is more common for socio-economically disadvantaged groups to commute using physically active modes. This association is, however, weakening and may soon reverse for cycling. At a population level, commute modal share provides a reasonable proxy for broader travel patterns, enhancing the value of the census in characterising background trends and evaluating interventions.

  14. Walking, Cycling and Driving to Work in the English and Welsh 2011 Census: Trends, Socio-Economic Patterning and Relevance to Travel Behaviour in General

    PubMed Central

    Goodman, Anna

    2013-01-01

    Objectives Increasing walking and cycling, and reducing motorised transport, are health and environmental priorities. This paper examines levels and trends in the use of different commute modes in England and Wales, both overall and with respect to small-area deprivation. It also investigates whether commute modal share can serve as a proxy for travel behaviour more generally. Methods 23.7 million adult commuters reported their usual main mode of travelling to work in the 2011 census in England and Wales; similar data were available for 1971–2001. Indices of Multiple Deprivation were used to characterise socio-economic patterning. The National Travel Survey (2002–2010) was used to examine correlations between commute modal share and modal share of total travel time. These correlations were calculated across 150 non-overlapping populations defined by region, year band and income. Results Among commuters in 2011, 67.1% used private motorised transport as their usual main commute mode (−1.8 percentage-point change since 2001); 17.8% used public transport (+1.8% change); 10.9% walked (−0.1% change); and 3.1% cycled (+0.1% change). Walking and, to a marginal extent, cycling were more common among those from deprived areas, but these gradients had flattened over the previous decade to the point of having essentially disappeared for cycling. In the National Travel Survey, commute modal share and total modal share were reasonably highly correlated for private motorised transport (r = 0.94), public transport (r = 0.96), walking (r = 0.88 excluding London) and cycling (r = 0.77). Conclusions England and Wales remain car-dependent, but the trends are slightly more encouraging. Unlike many health behaviours, it is more common for socio-economically disadvantaged groups to commute using physically active modes. This association is, however, weakening and may soon reverse for cycling. At a population level, commute modal share provides a reasonable proxy for broader travel patterns, enhancing the value of the census in characterising background trends and evaluating interventions. PMID:23990990

  15. Designing, Supporting, and Sustaining an Online Community of Practice: NASA EPO Workspace as an Ongoing Exploration of the Value of Community

    NASA Astrophysics Data System (ADS)

    Davey, B.; Davis, H. B.

    2015-12-01

    Increasingly, geographically diverse organizations, like NASA's Science Mission Directorate Education and Public Outreach personnel (SMD EPO), are looking for ways to facilitate group interactions in meaningful ways while limiting costs. Towards this end, of particular interest, and showing great potential are communities of practice. Communities of practice represent relationships in real-time between and among people sharing a common practice. They facilitate the sharing of information, building collective knowledge, and growing of the principles of practice. In 2010-11, SMD EPO established a website to support EPO professionals, facilitate headquarters reporting, and foster a community of practice. The purpose of this evaluation is to examine the design and use of the workspace and the value created for both individual community members and SMD EPO, the sponsoring organization. The online workspace was launched in 2010-11 for the members of NASA's SMDEPO community. The online workspace was designed to help facilitate the efficient sharing of information, be a central repository for resources, help facilitate and support knowledge creation, and ultimately lead to the development of an online community of practice. This study examines the role of the online workspace component of a community in the work of a community of practice. Much has been studied revealing the importance of communities of practice to organizations, project success, and knowledge management and some of these same successes hold true for virtual communities of practice. Additionally, we look at the outcomes of housting the online community for these past years in respect to knowledge building and personal and organizational value, the affects on professional dvelopment opportunities, how community members have benefited, and how the workspace has evolved to better serve the community.

  16. Determinants of quality of shared sanitation facilities in informal settlements: case study of Kisumu, Kenya.

    PubMed

    Simiyu, Sheillah; Swilling, Mark; Cairncross, Sandy; Rheingans, Richard

    2017-01-11

    Shared facilities are not recognised as improved sanitation due to challenges of maintenance as they easily can be avenues for the spread of diseases. Thus there is need to evaluate the quality of shared facilities, especially in informal settlements, where they are commonly used. A shared facility can be equated to a common good whose management depends on the users. If users do not work collectively towards keeping the facility clean, it is likely that the quality may depreciate due to lack of maintenance. This study examined the quality of shared sanitation facilities and used the common pool resource (CPR) management principles to examine the determinants of shared sanitation quality in the informal settlements of Kisumu, Kenya. Using a multiple case study design, the study employed both quantitative and qualitative methods. In both phases, users of shared sanitation facilities were interviewed, while shared sanitation facilities were inspected. Shared sanitation quality was a score which was the dependent variable in a regression analysis. Interviews during the qualitative stage were aimed at understanding management practices of shared sanitation users. Qualitative data was analysed thematically by following the CPR principles. Shared facilities, most of which were dirty, were shared by an average of eight households, and their quality decreased with an increase in the number of households sharing. The effect of numbers on quality is explained by behaviour reflected in the CPR principles, as it was easier to define boundaries of shared facilities when there were fewer users who cooperated towards improving their shared sanitation facility. Other factors, such as defined management systems, cooperation, collective decision making, and social norms, also played a role in influencing the behaviour of users towards keeping shared facilities clean and functional. Apart from hardware factors, quality of shared sanitation is largely due to group behaviour of users. The CPR principles form a crucial lens through which the dynamics of shared sanitation facilities in informal settlements can be understood. Development and policy efforts should incorporate group behaviour as they determine the quality of shared sanitation facilities.

  17. 10 CFR 603.535 - Value of proposed real property or equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Value of proposed real property or equipment. 603.535... AGREEMENTS Pre-Award Business Evaluation Cost Sharing § 603.535 Value of proposed real property or equipment. The contracting officer rarely should accept values for cost sharing contributions of real property or...

  18. 2 CFR 215.23 - Cost sharing or matching.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... determining cost sharing or matching for donated equipment, buildings and land for which title passes to the...

  19. 2 CFR 215.23 - Cost sharing or matching.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... determining cost sharing or matching for donated equipment, buildings and land for which title passes to the...

  20. 2 CFR 215.23 - Cost sharing or matching.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... determining cost sharing or matching for donated equipment, buildings and land for which title passes to the...

  1. Experimental Study of Split-Path Transmission Load Sharing

    NASA Technical Reports Server (NTRS)

    Krantz, Timothy L.; Delgado, Irebert R.

    1996-01-01

    Split-path transmissions are promising, attractive alternatives to the common planetary transmissions for helicopters. The split-path design offers two parallel paths for transmitting torque from the engine to the rotor. Ideally, the transmitted torque is shared equally between the two load paths; however, because of manufacturing tolerances, the design must be sized to allow for other than equal load sharing. To study the effect of tolerances, experiments were conducted using the NASA split-path test gearbox. Two gearboxes, nominally identical except for manufacturing tolerances, were tested. The clocking angle was considered to be a design parameter and used to adjust the load sharing of an otherwise fixed design. The torque carried in each path was measured for a matrix of input torques and clocking angles. The data were used to determine the optimal value and a tolerance for the clocking angles such that the most heavily loaded split path carried no greater than 53 percent of an input shaft torque of 367 N-m. The range of clocking angles satisfying this condition was -0.0012 +/- 0.0007 rad for box 1 and -0.0023 +/- 0.0009 rad for box 2. This study indicates that split-path gearboxes can be used successfully in rotorcraft and can be manufactured with existing technology.

  2. Quantifying heterogeneity attributable to polythetic diagnostic criteria: theoretical framework and empirical application.

    PubMed

    Olbert, Charles M; Gala, Gary J; Tupler, Larry A

    2014-05-01

    Heterogeneity within psychiatric disorders is both theoretically and practically problematic: For many disorders, it is possible for 2 individuals to share very few or even no symptoms in common yet share the same diagnosis. Polythetic diagnostic criteria have long been recognized to contribute to this heterogeneity, yet no unified theoretical understanding of the coherence of symptom criteria sets currently exists. A general framework for analyzing the logical and mathematical structure, coherence, and diversity of Diagnostic and Statistical Manual diagnostic categories (DSM-5 and DSM-IV-TR) is proposed, drawing from combinatorial mathematics, set theory, and information theory. Theoretical application of this framework to 18 diagnostic categories indicates that in most categories, 2 individuals with the same diagnosis may share no symptoms in common, and that any 2 theoretically possible symptom combinations will share on average less than half their symptoms. Application of this framework to 2 large empirical datasets indicates that patients who meet symptom criteria for major depressive disorder and posttraumatic stress disorder tend to share approximately three-fifths of symptoms in common. For both disorders in each of the datasets, pairs of individuals who shared no common symptoms were observed. Any 2 individuals with either diagnosis were unlikely to exhibit identical symptomatology. The theoretical and empirical results stemming from this approach have substantive implications for etiological research into, and measurement of, psychiatric disorders.

  3. Parallel checksumming of data chunks of a shared data object using a log-structured file system

    DOEpatents

    Bent, John M.; Faibish, Sorin; Grider, Gary

    2016-09-06

    Checksum values are generated and used to verify the data integrity. A client executing in a parallel computing system stores a data chunk to a shared data object on a storage node in the parallel computing system. The client determines a checksum value for the data chunk; and provides the checksum value with the data chunk to the storage node that stores the shared object. The data chunk can be stored on the storage node with the corresponding checksum value as part of the shared object. The storage node may be part of a Parallel Log-Structured File System (PLFS), and the client may comprise, for example, a Log-Structured File System client on a compute node or burst buffer. The checksum value can be evaluated when the data chunk is read from the storage node to verify the integrity of the data that is read.

  4. Information sharing and sorting in a community

    NASA Astrophysics Data System (ADS)

    Bhattacherjee, Biplab; Manna, S. S.; Mukherjee, Animesh

    2013-06-01

    We present the results of a detailed numerical study of a model for the sharing and sorting of information in a community consisting of a large number of agents. The information gathering takes place in a sequence of mutual bipartite interactions where randomly selected pairs of agents communicate with each other to enhance their knowledge and sort out the common information. Although our model is less restricted compared to the well-established naming game, the numerical results strongly indicate that the whole set of exponents characterizing this model are different from those of the naming game and they assume nontrivial values. Finally, it appears that in analogy to the emergence of clusters in the phenomenon of percolation, one can define clusters of agents here having the same information. We have studied in detail the growth of the largest cluster in this article and performed its finite-size scaling analysis.

  5. [Conditional pricing for innovative medicines in France: stop telling about risk-sharing!].

    PubMed

    Megerlin, F

    2013-09-01

    Across global borders and throughout the various sectors of health care, the search for viable methods to pay for value has intensified. Driven by soaring costs and constrained budgets, public and private payers are seeking innovative ways to incentivize providers and product manufacturers to focus on effective outcomes for patients according to key performance indexes. Conditional pricing and performance-based payment for innovative medicines could facilitate access to quasi-monopsonic french market, in a context of financial crisis, loss of reciprocal confidence, and growing aversion for therapeutic and economical uncertainty. However, we consider these new methods of payment should not be termed "risk-sharing agreements", a misleading term despite its common use today. They also should not impact the national list prices of medicines, that is a decisive tool for stabilizing international trade. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  6. Focus: who reaps the benefits of biodiversity?

    PubMed Central

    Karasov, C

    2001-01-01

    The search for wild plant and animal products of potential value to medicine, agriculture, and other uses has been going on for hundreds, possibly thousands, of years. Many commonly prescribed medicines in the United States include ingredients derived from natural products, and roughly 80% of the world's people rely on natural products for their primary medical needs. Until the past decade, all of these natural products were collected without compensating the source countries. But the rules of collecting changed in 1992 with the establishment of the Convention on Biological Diversity, which offers financial compensation for natural products and seeks to conserve biological diversity, use natural products sustainably, and fairly share products made from gene stocks. Questions remain, however, as to how to share the benefits of biodiversity equitably, as well as whether the lack of both U.S. support for the agreement and enforceability render the convention impotent. PMID:11748021

  7. Benefit sharing: an exploration on the contextual discourse of a changing concept

    PubMed Central

    2013-01-01

    Background The concept of benefit sharing has been a topical issue on the international stage for more than two decades, gaining prominence in international law, research ethics and political philosophy. In spite of this prominence, the concept of benefit sharing is not devoid of controversies related to its definition and justification. This article examines the discourses and justifications of benefit sharing concept. Discussion We examine the discourse on benefit sharing within three main spheres; namely: common heritage of humankind, access and use of genetic resources according to the Convention on Biological Diversity (CBD), and international clinical research. Benefit sharing has change from a concept that is enshrined in a legally binding regulation in the contexts of common heritage of humankind and CBD to a non-binding regulation in international clinical research. Nonetheless, there are more ethical justifications that accentuate benefit sharing in international clinical research than in the contexts of common heritage of humankind and the CBD. Summary There is a need to develop a legal framework in order to strengthen the advocacy and decisiveness of benefit sharing practice in international health research. Based on this legal framework, research sponsors would be required to provide a minimum set of possible benefits to participants and communities in research. Such legal framework on benefit sharing will encourage research collaboration with local communities; and dispel mistrust between research sponsors and host communities. However, more research is needed—drawing from other international legal frameworks, to understand how such a legal framework on benefit sharing can be successfully formulated in international health research. PMID:24028325

  8. 48 CFR 48.104-2 - Sharing acquisition savings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACT MANAGEMENT VALUE ENGINEERING Policies and Procedures 48.104-2 Sharing acquisition savings. (a... value engineering clause or alternate used, and the type of savings, as follows: Government/Contractor... percent for fixed-price contracts; or (2) 75 percent for cost-reimbursement contracts. Value engineering...

  9. Five-Year-Old Preschoolers' Sharing is Influenced by Anticipated Reciprocation.

    PubMed

    Xiong, Mingrui; Shi, Jiannong; Wu, Zhen; Zhang, Zhen

    2016-01-01

    Whether children share in anticipation of future benefits returned by a partner is an interesting question. In this study, 5-year-old children and an adult partner played a sharing game, in which children donated first and the partner donated afterward. In Experiment 1, the partner's resources were more attractive than the child's. In the reciprocal condition, the child was told that s/he would be a recipient when the partner played as a donor. In the non-reciprocal condition, however, the child was told that an anonymous child would be the recipient when the partner donated. Results showed that children shared more with the partner when they knew that they would be a recipient later. In Experiment 2, the child was always the recipient when the partner donated, but the partner's resources were more desirable than the child's in the high-value condition, and less desirable in the low-value condition. We found that children were more generous when the partner's resources were valued higher. These findings demonstrate that 5-year-old preschoolers' sharing choices take into account the anticipated reciprocity of the recipient, suggesting either self-interested tactical sharing or direct reciprocity in advance of receiving. Specifically, they adjust their sharing behavior depending on whether a partner has the potential to reciprocate, and whether it is worth sharing relative to the value of the payback.

  10. Echinococcus granulosus: absorption of cycloleucine and alpha-aminoisobutyric acid by protoscoleces.

    PubMed

    Jeffs, S A; Arme, C

    1986-02-01

    Protoscoleces of Echinococcus granulosus absorb the amino acids cycloleucine and alpha-aminoisobutyric acid (AIB) by a combination of mediated uptake and diffusion. After correcting for the latter, values for Kt and Vmax of 0.124 mM and 0.947 nmoles/mg protein/2 min for cycloleucine were calculated; corresponding values for AIB were 0.039 mM and 0.139 nmoles/mg protein/2 min. Both amino acids were accumulated against a concentration gradient and a comparison of Kt and Ki values determined in mutual inhibition experiments suggested that both cycloleucine and AIB share a common uptake locus (loci). Cycloleucine uptake was pH-dependent and could be inhibited by a variety of other amino acids. Neither D- nor L-proline inhibited cycloleucine absorption but D-methionine, D-alanine, D-leucine, D-valine and D-serine were much more effective inhibitors than their L-counterparts.

  11. Could Values and Social Structures in Singapore Facilitate Attainment of Patient-Focused, Cultural, and Linguistic Competency Standards in a Patient-Centered Medical Home Pilot?

    PubMed Central

    Shih, Jenny A; Shiow, Sue-Anne Toh Ee; Wee, Hwee-Lin

    2015-01-01

    Primary care practices in the United States are transforming into patient-centered medical homes (PCMHs) at a rapid pace. Newer PCMH standards have emphasized culturally and linguistically appropriate services (CLAS), but at this time, only some states in the United States have proposed or passed cultural competency training for health care professionals. Other countries are moving to PCMH models. Singapore, a small, ethnically diverse island nation, has national values and social structures that emphasize cultural and linguistic cohesion. In this piece, we examine Singapore’s first PCMH pilot with a national academic center and primary care practice group. Features such as common shared values, self-reliance, racial and religious harmony, patient experience surveillance, and incorporation of CLAS standards in routine health care transactions may predict success for the PCMH in Singapore, with some implications for the United States. PMID:28725822

  12. Marketplace Plans Provide Risk Protection, But Actuarial Values Overstate Realized Coverage For Most Enrollees.

    PubMed

    Polyakova, Maria; Hua, Lynn Mei; Bundorf, M Kate

    2017-12-01

    The Affordable Care Act (ACA) has increased the number of Americans with health insurance. Yet many policy makers and consumers have questioned the value of Marketplace plan coverage because of the generally high levels of cost sharing. We simulated out-of-pocket spending for bronze, silver, or gold Marketplace plans (those having actuarial values of 60 percent, 70 percent, and 80 percent, respectively). We found that for the vast majority of consumers, the proportion of covered spending paid by the plans is likely to be far less than their actuarial values, the metric commonly used to convey plan generosity. Indeed, only when annual health care spending exceeds $16,500 for bronze plans, $19,500 for silver plans, and $21,500 for gold plans do plans in these metal tiers cover the proportion of costs matching their actuarial values. While Marketplace plans substantially reduce consumers' exposure to financial risk relative to being uninsured, the use of actuarial values to communicate plan generosity is likely to be misleading to consumers.

  13. Distinct and Overlapping Brain Areas Engaged during Value-Based, Mathematical, and Emotional Decision Processing

    PubMed Central

    Hsu, Chun-Wei; Goh, Joshua O. S.

    2016-01-01

    When comparing between the values of different choices, human beings can rely on either more cognitive processes, such as using mathematical computation, or more affective processes, such as using emotion. However, the neural correlates of how these two types of processes operate during value-based decision-making remain unclear. In this study, we investigated the extent to which neural regions engaged during value-based decision-making overlap with those engaged during mathematical and emotional processing in a within-subject manner. In a functional magnetic resonance imaging experiment, participants viewed stimuli that always consisted of numbers and emotional faces that depicted two choices. Across tasks, participants decided between the two choices based on the expected value of the numbers, a mathematical result of the numbers, or the emotional face stimuli. We found that all three tasks commonly involved various cortical areas including frontal, parietal, motor, somatosensory, and visual regions. Critically, the mathematical task shared common areas with the value but not emotion task in bilateral striatum. Although the emotion task overlapped with the value task in parietal, motor, and sensory areas, the mathematical task also evoked responses in other areas within these same cortical structures. Minimal areas were uniquely engaged for the value task apart from the other two tasks. The emotion task elicited a more expansive area of neural activity whereas value and mathematical task responses were in more focal regions. Whole-brain spatial correlation analysis showed that valuative processing engaged functional brain responses more similarly to mathematical processing than emotional processing. While decisions on expected value entail both mathematical and emotional processing regions, mathematical processes have a more prominent contribution particularly in subcortical processes. PMID:27375466

  14. Distinct and Overlapping Brain Areas Engaged during Value-Based, Mathematical, and Emotional Decision Processing.

    PubMed

    Hsu, Chun-Wei; Goh, Joshua O S

    2016-01-01

    When comparing between the values of different choices, human beings can rely on either more cognitive processes, such as using mathematical computation, or more affective processes, such as using emotion. However, the neural correlates of how these two types of processes operate during value-based decision-making remain unclear. In this study, we investigated the extent to which neural regions engaged during value-based decision-making overlap with those engaged during mathematical and emotional processing in a within-subject manner. In a functional magnetic resonance imaging experiment, participants viewed stimuli that always consisted of numbers and emotional faces that depicted two choices. Across tasks, participants decided between the two choices based on the expected value of the numbers, a mathematical result of the numbers, or the emotional face stimuli. We found that all three tasks commonly involved various cortical areas including frontal, parietal, motor, somatosensory, and visual regions. Critically, the mathematical task shared common areas with the value but not emotion task in bilateral striatum. Although the emotion task overlapped with the value task in parietal, motor, and sensory areas, the mathematical task also evoked responses in other areas within these same cortical structures. Minimal areas were uniquely engaged for the value task apart from the other two tasks. The emotion task elicited a more expansive area of neural activity whereas value and mathematical task responses were in more focal regions. Whole-brain spatial correlation analysis showed that valuative processing engaged functional brain responses more similarly to mathematical processing than emotional processing. While decisions on expected value entail both mathematical and emotional processing regions, mathematical processes have a more prominent contribution particularly in subcortical processes.

  15. Qualitative Data Sharing Practices in Social Sciences

    ERIC Educational Resources Information Center

    Jeng, Wei

    2017-01-01

    Social scientists have been sharing data for a long time. Sharing qualitative data, however, has not become a common practice, despite the context of e-Research, information growth, and funding agencies' mandates on research data archiving and sharing. Since most systematic and comprehensive studies are based on quantitative data practices, little…

  16. Shared genetic variance between obesity and white matter integrity in Mexican Americans.

    PubMed

    Spieker, Elena A; Kochunov, Peter; Rowland, Laura M; Sprooten, Emma; Winkler, Anderson M; Olvera, Rene L; Almasy, Laura; Duggirala, Ravi; Fox, Peter T; Blangero, John; Glahn, David C; Curran, Joanne E

    2015-01-01

    Obesity is a chronic metabolic disorder that may also lead to reduced white matter integrity, potentially due to shared genetic risk factors. Genetic correlation analyses were conducted in a large cohort of Mexican American families in San Antonio (N = 761, 58% females, ages 18-81 years; 41.3 ± 14.5) from the Genetics of Brain Structure and Function Study. Shared genetic variance was calculated between measures of adiposity [(body mass index (BMI; kg/m(2)) and waist circumference (WC; in)] and whole-brain and regional measurements of cerebral white matter integrity (fractional anisotropy). Whole-brain average and regional fractional anisotropy values for 10 major white matter tracts were calculated from high angular resolution diffusion tensor imaging data (DTI; 1.7 × 1.7 × 3 mm; 55 directions). Additive genetic factors explained intersubject variance in BMI (heritability, h (2) = 0.58), WC (h (2) = 0.57), and FA (h (2) = 0.49). FA shared significant portions of genetic variance with BMI in the genu (ρG = -0.25), body (ρG = -0.30), and splenium (ρG = -0.26) of the corpus callosum, internal capsule (ρG = -0.29), and thalamic radiation (ρG = -0.31) (all p's = 0.043). The strongest evidence of shared variance was between BMI/WC and FA in the superior fronto-occipital fasciculus (ρG = -0.39, p = 0.020; ρG = -0.39, p = 0.030), which highlights region-specific variation in neural correlates of obesity. This may suggest that increase in obesity and reduced white matter integrity share common genetic risk factors.

  17. Discriminative and robust zero-watermarking scheme based on completed local binary pattern for authentication and copyright identification of medical images

    NASA Astrophysics Data System (ADS)

    Liu, Xiyao; Lou, Jieting; Wang, Yifan; Du, Jingyu; Zou, Beiji; Chen, Yan

    2018-03-01

    Authentication and copyright identification are two critical security issues for medical images. Although zerowatermarking schemes can provide durable, reliable and distortion-free protection for medical images, the existing zerowatermarking schemes for medical images still face two problems. On one hand, they rarely considered the distinguishability for medical images, which is critical because different medical images are sometimes similar to each other. On the other hand, their robustness against geometric attacks, such as cropping, rotation and flipping, is insufficient. In this study, a novel discriminative and robust zero-watermarking (DRZW) is proposed to address these two problems. In DRZW, content-based features of medical images are first extracted based on completed local binary pattern (CLBP) operator to ensure the distinguishability and robustness, especially against geometric attacks. Then, master shares and ownership shares are generated from the content-based features and watermark according to (2,2) visual cryptography. Finally, the ownership shares are stored for authentication and copyright identification. For queried medical images, their content-based features are extracted and master shares are generated. Their watermarks for authentication and copyright identification are recovered by stacking the generated master shares and stored ownership shares. 200 different medical images of 5 types are collected as the testing data and our experimental results demonstrate that DRZW ensures both the accuracy and reliability of authentication and copyright identification. When fixing the false positive rate to 1.00%, the average value of false negative rates by using DRZW is only 1.75% under 20 common attacks with different parameters.

  18. 38 CFR 43.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  19. 43 CFR 12.64 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  20. 7 CFR 3016.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  1. 36 CFR 1207.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  2. 40 CFR 31.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  3. 7 CFR 3016.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  4. 38 CFR 43.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  5. 43 CFR 12.64 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  6. 32 CFR 33.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  7. 36 CFR § 1207.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  8. 7 CFR 3016.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  9. 41 CFR 105-71.124 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  10. 43 CFR 12.64 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  11. 38 CFR 43.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  12. 32 CFR 33.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  13. 43 CFR 12.64 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  14. 41 CFR 105-71.124 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  15. 40 CFR 31.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  16. 38 CFR 43.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  17. 40 CFR 31.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  18. 41 CFR 105-71.124 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  19. 38 CFR 43.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  20. 45 CFR 2541.240 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  1. 41 CFR 105-71.124 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  2. 7 CFR 3016.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  3. 7 CFR 3016.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  4. 32 CFR 33.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  5. 32 CFR 33.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  6. 41 CFR 105-71.124 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  7. 45 CFR 2541.240 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  8. 32 CFR 33.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  9. 40 CFR 31.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  10. 36 CFR 1207.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  11. 43 CFR 12.64 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... donations from non-Federal third parties. (2) The value of third party in-kind contributions applicable to... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  12. 40 CFR 31.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... from non-Federal third parties. (2) The value of third party in-kind contributions applicable to the... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  13. 45 CFR 2541.240 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  14. 45 CFR 2541.240 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  15. 36 CFR 1207.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... others cash donations from non-Federal third parties. (2) The value of third party in-kind contributions... towards other Federal costs-sharing requirements. Neither costs nor the values of third party in-kind... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  16. 45 CFR 2541.240 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  17. Data sharing platforms for de-identified data from human clinical trials.

    PubMed

    Huser, Vojtech; Shmueli-Blumberg, Dikla

    2018-04-01

    Data sharing of de-identified individual participant data is being adopted by an increasing number of sponsors of human clinical trials. In addition to standardizing data syntax for shared trial data, semantic integration of various data elements is the focus of several initiatives that define research common data elements. This perspective article, in the first part, compares several data sharing platforms for de-identified clinical research data in terms of their size, policies and supported features. In the second part, we use a case study approach to describe in greater detail one data sharing platform (Data Share from National Institute of Drug Abuse). We present data on the past use of the platform, data formats offered, data de-identification approaches and its use of research common data elements. We conclude with a summary of current and expected future trends that facilitate secondary research use of data from completed human clinical trials.

  18. Do Librarians Have a Shared Set of Values? A Comparative Study of 36 Codes of Ethics Based on Gorman's "Enduring Values"

    ERIC Educational Resources Information Center

    Foster, Catherine; McMenemy, David

    2012-01-01

    Thirty-six ethical codes from national professional associations were studied, the aim to test whether librarians have global shared values or if political and cultural contexts have significantly influenced the codes' content. Gorman's eight core values of stewardship, service, intellectual freedom, rationalism, literacy and learning, equity of…

  19. 75 FR 76056 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... Change Relating to the Calculation of Net Asset Value for the iShares[supreg] Gold Trust November 30... iShares[supreg] Gold Trust (``Trust''), which is currently listed on the Exchange, will value the gold owned by the iShares Gold Trust on the basis of the London PM Fix instead of the COMEX settlement...

  20. Tacit Knowledge Sharing Modes of University Teachers from the Perspectives of Psychological Risk and Value

    ERIC Educational Resources Information Center

    Yu, Dengke; Zhou, Rong

    2015-01-01

    Tacit knowledge sharing (TKS) is important to improve the teaching skill and researching knowledge of university teachers. In this paper, the tacit knowledge sharing of university teachers is catalogued as four modes from perspectives of the psychological risk and psychological value which are measured by two grades--high and low. The four modes…

  1. Integrating Engineering into K-6 Curriculum: Developing Talent in the STEM Disciplines

    ERIC Educational Resources Information Center

    Mann, Eric L.; Mann, Rebecca L.; Strutz, Michele L.; Duncan, Daphne; Yoon, So Yoon

    2011-01-01

    The fields of gifted and engineering education share many common interests, and their students share many common attributes. Infusing and making engineering implicit in the K-6 education programs creates opportunities to develop concepts, skills, and habits of the mind that are valuable in all disciplines while providing opportunities to discover…

  2. Measuring and Sustaining the Impact of Less Commonly Taught Language Collections in a Research Library

    ERIC Educational Resources Information Center

    Lenkart, Joe; Teper, Thomas H.; Thacker, Mara; Witt, Steven W.

    2015-01-01

    To evaluate the current state of resource sharing and cooperative collection development, this paper examines the relationship between less commonly taught language collections (LCTL) and ILL services. The study examined multiple years of the University of Illinois at Urbana-Champaign's resource-sharing data. This paper provides a historical…

  3. An Integrated Architecture to Support Hastily Formed Network (HFN)

    DTIC Science & Technology

    2007-12-01

    17 1. Creating Awareness of the Situation (intra-organization).............17 2. Sharing Awareness Among Organizations (inter...Convergence - Sharing a Common Goal to Achieve a Common Outcome...................................................................39 b. Interdependency and...Weaknesses, Opportunities and Threat UC Unclassified UCC Unified Command Center UHF Ultra High Frequency VHF Very High Frequency VoIP Voice over

  4. Designing for Global Data Sharing, Designing for Educational Transformation

    ERIC Educational Resources Information Center

    Adams, Robin S.; Radcliffe, David; Fosmire, Michael

    2016-01-01

    This paper provides an example of a global data sharing project with an educational transformation agenda. This agenda shaped both the design of the shared dataset and the experience of sharing the common dataset to support multiple perspective inquiry and enable integrative and critically reflexive research-to-practice dialogue. The shared…

  5. Community action and research as citizenship construction.

    PubMed

    Montero, Maritza

    2009-03-01

    Social change, well-being and liberation have been intertwined in community research and action, as much as being used as political common-places. In this paper, it is argued that community research and action can have a political character. The epistemological premises shared by both the community and political spheres are discussed, and concepts are defined. The way community psychological action can produce changes is illustrated by an experience carried out with children from poverty sectors of Caracas, Venezuela, intended to construct citizenship by developing awareness about values, civic rights and duties, while experiencing the advantages of participation, peaceful negotiation and solidarity, during art classes. Topics regarding citizenship values and ethics were painted and discussed in a participatory way. Results about how the children developed consciousness about those topics, relating them to their lives, are presented.

  6. Making One Health a reality: crossing bureaucratic boundaries: Chapter 18 in One Health

    USGS Publications Warehouse

    Rubin, Carol; Dunham, Bernadette; Sleeman, Jonathan

    2014-01-01

    A One Health approach that achieves optimal outcomes requires that nontraditional partners come to a common table to identify solutions that transcend organization-specific mandates. This collaboration requires individuals to go beyond their accustomed comfort zones and function on teams with partners who very likely come from unfamiliar organizational, disciplinary, and even national cultures. Each participant represents a separate mandate and an individual corporate culture and values, and each potentially communicates in agency-specific or industry-prescribed cultural terms that may be foreign to the rest of the team. A recent review paper reports that such interdisciplinary teams are most likely to succeed when they have a unified task and a shared goal and values, and when personal relationships are developed from a foundation of trust and respect (1).

  7. How strong are passwords used to protect personal health information in clinical trials?

    PubMed

    El Emam, Khaled; Moreau, Katherine; Jonker, Elizabeth

    2011-02-11

    Findings and statements about how securely personal health information is managed in clinical research are mixed. The objective of our study was to evaluate the security of practices used to transfer and share sensitive files in clinical trials. Two studies were performed. First, 15 password-protected files that were transmitted by email during regulated Canadian clinical trials were obtained. Commercial password recovery tools were used on these files to try to crack their passwords. Second, interviews with 20 study coordinators were conducted to understand file-sharing practices in clinical trials for files containing personal health information. We were able to crack the passwords for 93% of the files (14/15). Among these, 13 files contained thousands of records with sensitive health information on trial participants. The passwords tended to be relatively weak, using common names of locations, animals, car brands, and obvious numeric sequences. Patient information is commonly shared by email in the context of query resolution. Files containing personal health information are shared by email and, by posting them on shared drives with common passwords, to facilitate collaboration. If files containing sensitive patient information must be transferred by email, mechanisms to encrypt them and to ensure that password strength is high are necessary. More sophisticated collaboration tools are required to allow file sharing without password sharing. We provide recommendations to implement these practices.

  8. How Strong are Passwords Used to Protect Personal Health Information in Clinical Trials?

    PubMed Central

    Moreau, Katherine; Jonker, Elizabeth

    2011-01-01

    Background Findings and statements about how securely personal health information is managed in clinical research are mixed. Objective The objective of our study was to evaluate the security of practices used to transfer and share sensitive files in clinical trials. Methods Two studies were performed. First, 15 password-protected files that were transmitted by email during regulated Canadian clinical trials were obtained. Commercial password recovery tools were used on these files to try to crack their passwords. Second, interviews with 20 study coordinators were conducted to understand file-sharing practices in clinical trials for files containing personal health information. Results We were able to crack the passwords for 93% of the files (14/15). Among these, 13 files contained thousands of records with sensitive health information on trial participants. The passwords tended to be relatively weak, using common names of locations, animals, car brands, and obvious numeric sequences. Patient information is commonly shared by email in the context of query resolution. Files containing personal health information are shared by email and, by posting them on shared drives with common passwords, to facilitate collaboration. Conclusion If files containing sensitive patient information must be transferred by email, mechanisms to encrypt them and to ensure that password strength is high are necessary. More sophisticated collaboration tools are required to allow file sharing without password sharing. We provide recommendations to implement these practices. PMID:21317106

  9. Good Neighbors: Shared Challenges and Solutions Toward Increasing Value at Academic Medical Centers and Universities.

    PubMed

    Clancy, Gerard P

    2015-12-01

    Academic medical centers (AMCs) and universities are experiencing increasing pressure to enhance the value they offer at the same time that they are facing challenges related to outcomes, controlling costs, new competition, and government mandates. Yet, rarely do the leaders of these academic neighbors work cooperatively to enhance value. In this Perspective the author, a former university regional campus president with duties in an AMC as an academic physician, shares his insights into the shared challenges these academic neighbors face in improving the value of their services in complex environments. He describes the successes some AMCs have had in generating revenues from new clinical programs that reduce the overall cost of care for larger populations. He also describes how several universities have taken a comprehensive approach to reduce overhead and administrative costs. The author identifies six themes related to successful value improvement efforts and provides examples of successful strategies used by AMCs and their university neighbors to improve the overall value of their programs. He concludes by encouraging leaders of AMCs and universities to share information about their successes in value improvements with each other, to seek additional joint value enhancement efforts, and to market their value improvements to the public.

  10. The ethics of human reproductive cloning: when world views collide.

    PubMed

    Cohen, Cynthia B

    2004-01-01

    Two camps in bioethics with seemingly opposing world views have staked out conflicting positions regarding the ethics of human reproductive cloning. These camps do not appear to share common concepts or ways of reasoning through which to exchange views and come to a meeting of minds about uses of this technology. Yet analysis of their respective approaches to several issues surrounding reproductive cloning, such as where the ethical limits of individual reproductive choice lie, whether the use of this technology would violate human dignity, whether it would create risks to the resulting fetuses and children that would make its use intolerable, and whether it would challenge certain core social values, reveals that they are not wholly opposed to one another. Indeed, it displays that they hold certain beliefs, values, and concerns in common. Moreover, it indicates that the different world views that they each presuppose, while flawed in certain respects, do not collide in every respect, but can be reconciled in significant ways that provide fertile ground for agreement about several issues related to human reproductive cloning.

  11. 15 CFR 24.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  12. 45 CFR 602.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  13. 44 CFR 13.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  14. 10 CFR 600.224 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  15. 45 CFR 92.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  16. 29 CFR 97.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  17. 28 CFR 66.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  18. 45 CFR 1157.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  19. 45 CFR 602.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  20. 14 CFR 1273.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  1. 29 CFR 1470.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  2. 45 CFR 92.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  3. 21 CFR 1403.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  4. 45 CFR 1183.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  5. 44 CFR 13.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  6. 29 CFR 1470.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  7. 24 CFR 85.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  8. 45 CFR 1157.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  9. 29 CFR 97.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  10. 29 CFR 97.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  11. 13 CFR 143.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  12. 45 CFR 1183.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  13. 28 CFR 66.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  14. 20 CFR 437.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... non-Federal grants or by other cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  15. 29 CFR 1470.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  16. 21 CFR 1403.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  17. 45 CFR 92.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  18. 49 CFR 18.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  19. 45 CFR 1174.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  20. 22 CFR 135.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  1. 14 CFR 1273.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  2. 45 CFR 602.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  3. 49 CFR 18.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  4. 45 CFR 92.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  5. 22 CFR 135.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  6. 29 CFR 97.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  7. 49 CFR 18.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  8. 24 CFR 85.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  9. 29 CFR 97.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  10. 45 CFR 1174.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  11. 10 CFR 600.224 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  12. 20 CFR 437.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... non-Federal grants or by other cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  13. 22 CFR 135.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  14. 34 CFR 80.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  15. 10 CFR 600.224 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  16. 44 CFR 13.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  17. 28 CFR 66.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  18. 45 CFR 92.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  19. 24 CFR 85.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  20. 45 CFR 1174.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  1. 44 CFR 13.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  2. 45 CFR 602.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  3. 15 CFR 24.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  4. 10 CFR 600.224 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  5. 21 CFR 1403.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  6. 34 CFR 80.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  7. 13 CFR 143.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  8. 44 CFR 13.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  9. 22 CFR 135.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  10. 14 CFR § 1273.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... parties. (2) The value of third party in-kind contributions applicable to the period to which the cost... costs-sharing requirements. Neither costs nor the values of third party in-kind contributions may count... records of grantees and subgrantee or cost-type contractors. These records must show how the value placed...

  11. 24 CFR 85.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  12. 34 CFR 80.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  13. 10 CFR 600.224 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  14. 13 CFR 143.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  15. 34 CFR 80.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  16. 28 CFR 66.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  17. 13 CFR 143.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  18. 45 CFR 1183.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  19. 24 CFR 85.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  20. 45 CFR 1183.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  1. 45 CFR 1174.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  2. 15 CFR 24.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  3. 14 CFR 1273.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  4. 15 CFR 24.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  5. 45 CFR 1157.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  6. 45 CFR 1174.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  7. 21 CFR 1403.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  8. 49 CFR 18.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  9. 14 CFR 1273.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  10. 45 CFR 1157.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  11. 45 CFR 1183.24 - Matching or cost sharing.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  12. 29 CFR 1470.24 - Matching or cost sharing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  13. 22 CFR 135.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  14. 29 CFR 1470.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  15. 21 CFR 1403.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  16. 13 CFR 143.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) The value of third party in-kind contributions applicable to the period to which the cost sharing or.... Neither costs nor the values of third party in-kind contributions may count towards satisfying a cost... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  17. 34 CFR 80.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... must show how the value placed on third party in-kind contributions was derived. To the extent feasible...

  18. 45 CFR 602.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... contractors. These records must show how the value placed on third party in-kind contributions was derived. To...

  19. 45 CFR 1157.24 - Matching or cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... grants or by others cash donations from non-Federal third parties. (2) The value of third party in-kind... contributions counted towards other Federal costs-sharing requirements. Neither costs nor the values of third... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  20. 20 CFR 437.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... non-Federal grants or by other cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  1. 28 CFR 66.24 - Matching or cost sharing.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... non-Federal grants or by others cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  2. 20 CFR 437.24 - Matching or cost sharing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... non-Federal grants or by other cash donations from non-Federal third parties. (2) The value of third... values of third party in-kind contributions may count towards satisfying a cost sharing or matching... records must show how the value placed on third party in-kind contributions was derived. To the extent...

  3. Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

    PubMed

    Zeng, Yanni; Navarro, Pau; Xia, Charley; Amador, Carmen; Fernandez-Pujals, Ana M; Thomson, Pippa A; Campbell, Archie; Nagy, Reka; Clarke, Toni-Kim; Hafferty, Jonathan D; Smith, Blair H; Hocking, Lynne J; Padmanabhan, Sandosh; Hayward, Caroline; MacIntyre, Donald J; Porteous, David J; Haley, Chris S; McIntosh, Andrew M

    2016-12-01

    Both genetic and environmental factors contribute to risk of depression, but estimates of their relative contributions are limited. Commonalities between clinically-assessed major depressive disorder (MDD) and self-declared depression (SDD) are also unclear. Using data from a large Scottish family-based cohort (GS:SFHS, N=19,994), we estimated the genetic and environmental variance components for MDD and SDD. The components representing the genetic effect associated with genome-wide common genetic variants (SNP heritability), the additional pedigree-associated genetic effect and non-genetic effects associated with common environments were estimated in a linear mixed model (LMM). Both MDD and SDD had significant contributions from components representing the effect from common genetic variants, the additional genetic effect associated with the pedigree and the common environmental effect shared by couples. The estimate of correlation between SDD and MDD was high (r=1.00, se=0.20) for common-variant-associated genetic effect and lower for the additional genetic effect from the pedigree (r=0.57, se=0.08) and the couple-shared environmental effect (r=0.53, se=0.22). Both genetics and couple-shared environmental effects were major factors influencing liability to depression. SDD may provide a scalable alternative to MDD in studies seeking to identify common risk variants. Rarer variants and environmental effects may however differ substantially according to different definitions of depression. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  4. Cross-Jurisdictional Resource Sharing in Local Health Departments: Implications for Services, Quality, and Cost.

    PubMed

    Humphries, Debbie L; Hyde, Justeen; Hahn, Ethan; Atherly, Adam; O'Keefe, Elaine; Wilkinson, Geoffrey; Eckhouse, Seth; Huleatt, Steve; Wong, Samuel; Kertanis, Jennifer

    2018-01-01

    Forty one percent of local health departments in the U.S. serve jurisdictions with populations of 25,000 or less. Researchers, policymakers, and advocates have long questioned how to strengthen public health systems in smaller municipalities. Cross-jurisdictional sharing may increase quality of service, access to resources, and efficiency of resource use. To characterize perceived strengths and challenges of independent and comprehensive sharing approaches, and to assess cost, quality, and breadth of services provided by independent and sharing health departments in Connecticut (CT) and Massachusetts (MA). We interviewed local health directors or their designees from 15 comprehensive resource-sharing jurisdictions and 54 single-municipality jurisdictions in CT and MA using a semi-structured interview. Quantitative data were drawn from closed-ended questions in the semi-structured interviews; municipal demographic data were drawn from the American Community Survey and other public sources. Qualitative data were drawn from open-ended questions in the semi-structured interviews. The findings from this multistate study highlight advantages and disadvantages of two common public health service delivery models - independent and shared. Shared service jurisdictions provided more community health programs and services, and invested significantly more ($120 per thousand (1K) population vs. $69.5/1K population) on healthy food access activities. Sharing departments had more indicators of higher quality food safety inspections (FSIs), and there was a non-linear relationship between cost per FSI and number of FSI. Minimum cost per FSI was reached above the total number of FSI conducted by all but four of the jurisdictions sampled. Independent jurisdictions perceived their governing bodies to have greater understanding of the roles and responsibilities of local public health, while shared service jurisdictions had fewer staff per 1,000 population. There are trade-offs with sharing and remaining independent. Independent health departments serving small jurisdictions have limited resources but strong local knowledge. Multi-municipality departments have more resources but require more time and investment in governance and decision-making. When making decisions about the right service delivery model for a given municipality, careful consideration should be given to local culture and values. Some economies of scale may be achieved through resource sharing for municipalities <25,000 population.

  5. A Path to Successful Energy Retrofits: Early Collaboration through Integrated Project Delivery Teams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parrish, Kristen

    2012-10-01

    This document guides you through a process for the early design phases of retrofit projects to help you mitigate frustrations commonly experienced by building owners and designers. It outlines the value of forming an integrated project delivery team and developing a communication and information-sharing infrastructure that fosters collaboration. This guide does not present a complete process for designing an energy retrofit for a building. Instead, it focuses on the early design phase tasks related to developing and selecting energy efficiency measures (EEMs) that benefit from collaboration, and highlights the resulting advantages.

  6. 26 CFR 25.2512-2 - Stocks and bonds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... prices on the date of the gift is the fair market value per share or bond. If there were no sales on the... trading days after (Wednesday, June 20) and on these days the mean sale prices per share were $10 and $15, respectively. The price of $12 is taken as representing the fair market value of a share of stock as of the...

  7. A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics.

    PubMed

    Lopatto, David; Hauser, Charles; Jones, Christopher J; Paetkau, Don; Chandrasekaran, Vidya; Dunbar, David; MacKinnon, Christy; Stamm, Joyce; Alvarez, Consuelo; Barnard, Daron; Bedard, James E J; Bednarski, April E; Bhalla, Satish; Braverman, John M; Burg, Martin; Chung, Hui-Min; DeJong, Randall J; DiAngelo, Justin R; Du, Chunguang; Eckdahl, Todd T; Emerson, Julia; Frary, Amy; Frohlich, Donald; Goodman, Anya L; Gosser, Yuying; Govind, Shubha; Haberman, Adam; Hark, Amy T; Hoogewerf, Arlene; Johnson, Diana; Kadlec, Lisa; Kaehler, Marian; Key, S Catherine Silver; Kokan, Nighat P; Kopp, Olga R; Kuleck, Gary A; Lopilato, Jane; Martinez-Cruzado, Juan C; McNeil, Gerard; Mel, Stephanie; Nagengast, Alexis; Overvoorde, Paul J; Parrish, Susan; Preuss, Mary L; Reed, Laura D; Regisford, E Gloria; Revie, Dennis; Robic, Srebrenka; Roecklien-Canfield, Jennifer A; Rosenwald, Anne G; Rubin, Michael R; Saville, Kenneth; Schroeder, Stephanie; Sharif, Karim A; Shaw, Mary; Skuse, Gary; Smith, Christopher D; Smith, Mary; Smith, Sheryl T; Spana, Eric P; Spratt, Mary; Sreenivasan, Aparna; Thompson, Jeffrey S; Wawersik, Matthew; Wolyniak, Michael J; Youngblom, James; Zhou, Leming; Buhler, Jeremy; Mardis, Elaine; Leung, Wilson; Shaffer, Christopher D; Threlfall, Jennifer; Elgin, Sarah C R

    2014-01-01

    In their 2012 report, the President's Council of Advisors on Science and Technology advocated "replacing standard science laboratory courses with discovery-based research courses"-a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences working with the Genomics Education Partnership, a nationwide faculty consortium that aims to provide undergraduates with a research experience in genomics through a scheduled course (a classroom-based undergraduate research experience, or CURE). We examine the common barriers encountered in implementing a CURE, program elements of most value to faculty, ways in which a shared core support system can help, and the incentives for and rewards of establishing a CURE on our diverse campuses. While some of the barriers and rewards are specific to a research project utilizing a genomics approach, other lessons learned should be broadly applicable. We find that a central system that supports a shared investigation can mitigate some shortfalls in campus infrastructure (such as time for new curriculum development, availability of IT services) and provides collegial support for change. Our findings should be useful for designing similar supportive programs to facilitate change in the way we teach science for undergraduates. © 2014 D. Lopatto et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  8. Extending the Shared Socioeconomic Pathways for sub-national impacts, adaptation, and vulnerability studies

    DOE PAGES

    Absar, Syeda Mariya; Preston, Benjamin L.

    2015-05-25

    The exploration of alternative socioeconomic futures is an important aspect of understanding the potential consequences of climate change. While socioeconomic scenarios are common and, at times essential, tools for the impact, adaptation and vulnerability and integrated assessment modeling research communities, their approaches to scenario development have historically been quite distinct. However, increasing convergence of impact, adaptation and vulnerability and integrated assessment modeling research in terms of scales of analysis suggests there may be value in the development of a common framework for socioeconomic scenarios. The Shared Socioeconomic Pathways represents an opportunity for the development of such a common framework. However,more » the scales at which these global storylines have been developed are largely incommensurate with the sub-national scales at which impact, adaptation and vulnerability, and increasingly integrated assessment modeling, studies are conducted. Our objective for this study was to develop sub-national and sectoral extensions of the global SSP storylines in order to identify future socioeconomic challenges for adaptation for the U.S. Southeast. A set of nested qualitative socioeconomic storyline elements, integrated storylines, and accompanying quantitative indicators were developed through an application of the Factor-Actor-Sector framework. Finally, in addition to revealing challenges and opportunities associated with the use of the SSPs as a basis for more refined scenario development, this study generated sub-national storyline elements and storylines that can subsequently be used to explore the implications of alternative subnational socioeconomic futures for the assessment of climate change impacts and adaptation.« less

  9. Consumer Outcomes After Implementing CommonGround as an Approach to Shared Decision Making.

    PubMed

    Salyers, Michelle P; Fukui, Sadaaki; Bonfils, Kelsey A; Firmin, Ruth L; Luther, Lauren; Goscha, Rick; Rapp, Charles A; Holter, Mark C

    2017-03-01

    The authors examined consumer outcomes before and after implementing CommonGround, a computer-based shared decision-making program. Consumers with severe mental illness (N=167) were interviewed prior to implementation and 12 and 18 months later to assess changes in active treatment involvement, symptoms, and recovery-related attitudes. Providers also rated consumers on level of treatment involvement. Most consumers used CommonGround at least once (67%), but few used the program regularly. Mixed-effects regression analyses showed improvement in self-reported symptoms and recovery attitudes. Self-reported treatment involvement did not change; however, for a subset of consumers with the same providers over time (N=83), the providers rated consumers as more active in treatment. This study adds to the growing literature on tools to support shared decision making, showing the potential benefits of CommonGround for improving recovery outcomes. More work is needed to better engage consumers in CommonGround and to test the approach with more rigorous methods.

  10. To Share or Not to Share: Parental, Sibling, and Situational Influences on Sharing with a Younger Sibling

    ERIC Educational Resources Information Center

    Van Berkel, Sheila R.; Van der Pol, Lotte D.; Groeneveld, Marleen G.; Hallers-Haalboom, Elizabeth T.; Endendijk, Joyce J.; Mesman, Judi; Bakermans-Kranenburg, Marian J.

    2015-01-01

    Sharing is an important indicator of internalised prosocial values. We examined predictors of sharing of 302 preschoolers with their younger siblings in a one-year longitudinal study. Sharing was observed during different home visits, once with father and once with mother. We examined the following predictors: both children's externalising…

  11. Shared decision making as part of value based care: New U.S. policies challenge our readiness.

    PubMed

    Spatz, Erica S; Elwyn, Glyn; Moulton, Benjamin W; Volk, Robert J; Frosch, Dominick L

    2017-06-01

    Shared decision making in the United States is increasingly being recognized as part of value-based care. During the last decade, several state and federal initiatives have linked shared decision making with reimbursement and increased protection from litigation. Additionally, private and public foundations are increasingly funding studies to identify best practices for moving shared decision making from the research world into clinical practice. These shifts offer opportunities and challenges for ensuring effective implementation. Copyright © 2017. Published by Elsevier GmbH.

  12. Five Policy Levers To Meet The Value Challenge In Cancer Care.

    PubMed

    Callahan, Ryan; Darzi, Ara

    2015-09-01

    The burden of cancer on public finances is a serious concern for policy makers. More people are developing cancer, and as standards of care have risen, more are surviving and requiring longer-term care. Precision medicine promises better outcomes but demands commensurately higher payments for care. As both incidence and per case costs rise, we suggest that the task of expanding access to high-quality cancer care poses a "value challenge" that policies in many countries are inadequate to meet. Policy makers should respond with a new approach. We explore questions that policy makers will need to consider regarding objectives, barriers, and levers for policy development. We use transparency and accountability as cornerstones of a new approach to promote value-based decision making. Although barriers to advancing this agenda are formidable, we recommend that governments define common standards for value-based accounting; serve as information brokers for evidence development; pioneer value-based procurement of goods and services; engage in deliberative democracy in cancer care; and educate communities to facilitate knowledge sharing between communities of patients, their caretakers, and researchers. Project HOPE—The People-to-People Health Foundation, Inc.

  13. Cooperation partners in information sharing within the context of an Asian cancer network.

    PubMed

    Kawahara, Norie

    2007-01-01

    It would be a great mistake to analyze the health situation in Asia relying on the focus on individualism inherent in the sense of values of Europeans and Americans. Cooperation across fields is indispensable for effective control of the epidemic of disease we are facing in the 21st century. We need to concentrate efforts on bringing together specialists, not only within the various areas of medical practice, but also across such fields as economics, politics and information technology (IT). Asia differs from Europe and America in that it does not have any group political structure and therefore we must rely on voluntary integration of our efforts if we are to achieve the most effective application of our combined resources. Non-intervention in internal affairs is naturally a very important condition for success. Sharing of information while abiding by national regulations regarding medical data confidentiality does pose difficulties, but gentle persuasion to standardize processes with a shared commitment to overcoming problems should reduce opposition. Our common purpose in maintaining healthy societies, whether we be scientists, medical staff, economists, computer specialists or politicians, provides the bond. Ways and means by which this bond can be strengthened deserve our attention.

  14. Assembling networks of microbial genomes using linear programming.

    PubMed

    Holloway, Catherine; Beiko, Robert G

    2010-11-20

    Microbial genomes exhibit complex sets of genetic affinities due to lateral genetic transfer. Assessing the relative contributions of parent-to-offspring inheritance and gene sharing is a vital step in understanding the evolutionary origins and modern-day function of an organism, but recovering and showing these relationships is a challenging problem. We have developed a new approach that uses linear programming to find between-genome relationships, by treating tables of genetic affinities (here, represented by transformed BLAST e-values) as an optimization problem. Validation trials on simulated data demonstrate the effectiveness of the approach in recovering and representing vertical and lateral relationships among genomes. Application of the technique to a set comprising Aquifex aeolicus and 75 other thermophiles showed an important role for large genomes as 'hubs' in the gene sharing network, and suggested that genes are preferentially shared between organisms with similar optimal growth temperatures. We were also able to discover distinct and common genetic contributors to each sequenced representative of genus Pseudomonas. The linear programming approach we have developed can serve as an effective inference tool in its own right, and can be an efficient first step in a more-intensive phylogenomic analysis.

  15. Providing the Tools for Information Sharing: Net-Centric Enterprise Services

    DTIC Science & Technology

    2007-07-01

    The Department of Defense (DoD) is establishing a net-centric environment that increasingly leverages shared services and Service-Oriented...transformational program that delivers a set of shared services as part of the DoD’s common infrastructure to enable networked joint force capabilities, improved interoperability, and increased information sharing across mission area services.

  16. Shared decision making in chronic care in the context of evidence based practice in nursing.

    PubMed

    Friesen-Storms, Jolanda H H M; Bours, Gerrie J J W; van der Weijden, Trudy; Beurskens, Anna J H M

    2015-01-01

    In the decision-making environment of evidence-based practice, the following three sources of information must be integrated: research evidence of the intervention, clinical expertise, and the patient's values. In reality, evidence-based practice usually focuses on research evidence (which may be translated into clinical practice guidelines) and clinical expertise without considering the individual patient's values. The shared decision-making model seems to be helpful in the integration of the individual patient's values in evidence-based practice. We aim to discuss the relevance of shared decision making in chronic care and to suggest how it can be integrated with evidence-based practice in nursing. We start by describing the following three possible approaches to guide the decision-making process: the paternalistic approach, the informed approach, and the shared decision-making approach. Implementation of shared decision making has gained considerable interest in cases lacking a strong best-treatment recommendation, and when the available treatment options are equivalent to some extent. We discuss that in chronic care it is important to always invite the patient to participate in the decision-making process. We delineate the following six attributes of health care interventions in chronic care that influence the degree of shared decision making: the level of research evidence, the number of available intervention options, the burden of side effects, the impact on lifestyle, the patient group values, and the impact on resources. Furthermore, the patient's willingness to participate in shared decision making, the clinical expertise of the nurse, and the context in which the decision making takes place affect the shared decision-making process. A knowledgeable and skilled nurse with a positive attitude towards shared decision making—integrated with evidence-based practice—can facilitate the shared decision-making process. We conclude that nurses as well as other health care professionals in chronic care should integrate shared decision making with evidence-based practice to deliver patient-centred care. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Next-generation leadership development in family businesses: the critical roles of shared vision and family climate.

    PubMed

    Miller, Stephen P

    2014-01-01

    The multigenerational survival rate for family-owned businesses is not good. Lack of a shared vision for the family enterprise and weak next-generation leadership are often cited as two of the leading reasons for the failure of family firms to successfully transition from one generation of family ownership to the next. The climate of the business-owning family has also been suggested as important to the performance of the family enterprise. Despite these commonly held tenets, there is a lack of rigorous quantitative research that explores the relationships among these three factors. To address this gap, a quantitative study of 100 next-generation family firm leaders and 350 family and non-family leaders and employees with whom they work was conducted. The results demonstrate that a shared vision for the family business has a strong effect on the leadership effectiveness of next-generation family leaders and a moderate effect on the degree to which they are positively engaged with their work. The findings also show that two dimensions of family climate significantly influence the likelihood that a shared vision for the family firm has been created. Open communication in the family is positively related to the presence of a shared vision for the business. Intergenerational authority, which refers to a senior generation that exercises unquestioned authority and sets the rules, is negatively related to the presence of a shared vision. Surprisingly, a third dimension of family climate, cognitive cohesion, which includes shared values in the family, had no relationship with the degree to which there was a shared vision for the family business. The implications for family business owners is that they would be wise to spend as much time on fostering a positive family climate characterized by open communication as they do on creating and executing a successful business strategy if their goal is to pass the business from one generation of family owners to the next.

  18. Next-generation leadership development in family businesses: the critical roles of shared vision and family climate

    PubMed Central

    Miller, Stephen P.

    2014-01-01

    The multigenerational survival rate for family-owned businesses is not good. Lack of a shared vision for the family enterprise and weak next-generation leadership are often cited as two of the leading reasons for the failure of family firms to successfully transition from one generation of family ownership to the next. The climate of the business-owning family has also been suggested as important to the performance of the family enterprise. Despite these commonly held tenets, there is a lack of rigorous quantitative research that explores the relationships among these three factors. To address this gap, a quantitative study of 100 next-generation family firm leaders and 350 family and non-family leaders and employees with whom they work was conducted. The results demonstrate that a shared vision for the family business has a strong effect on the leadership effectiveness of next-generation family leaders and a moderate effect on the degree to which they are positively engaged with their work. The findings also show that two dimensions of family climate significantly influence the likelihood that a shared vision for the family firm has been created. Open communication in the family is positively related to the presence of a shared vision for the business. Intergenerational authority, which refers to a senior generation that exercises unquestioned authority and sets the rules, is negatively related to the presence of a shared vision. Surprisingly, a third dimension of family climate, cognitive cohesion, which includes shared values in the family, had no relationship with the degree to which there was a shared vision for the family business. The implications for family business owners is that they would be wise to spend as much time on fostering a positive family climate characterized by open communication as they do on creating and executing a successful business strategy if their goal is to pass the business from one generation of family owners to the next. PMID:25538639

  19. Indigenous Values and Health Systems Stewardship in Circumpolar Countries

    PubMed Central

    Chatwood, Susan; Paulette, Francois; Baker, G. Ross; Eriksen, Astrid M. A.; Hansen, Ketil Lenert; Eriksen, Heidi; Lavoie, Josée; Lou, Wendy; Mauro, Ian; Orbinski, James; Pambrun, Nathalie; Retallack, Hanna; Brown, Adalsteinn

    2017-01-01

    Circumpolar regions, and the nations within which they reside, have recently gained international attention because of shared and pressing public policy issues such as climate change, resource development, endangered wildlife and sovereignty disputes. In a call for national and circumpolar action on shared areas of concern, the Arctic states health ministers recently met and signed a declaration that identified shared priorities for international cooperation. Among the areas for collaboration raised, the declaration highlighted the importance of enhancing intercultural understanding, promoting culturally appropriate health care delivery and strengthening circumpolar collaboration in culturally appropriate health care delivery. This paper responds to the opportunity for further study to fully understand indigenous values and contexts, and presents these as they may apply to a framework that will support international comparisons and systems improvements within circumpolar regions. We explored the value base of indigenous peoples and provide considerations on how these values might interface with national values, health systems values and value bases between indigenous nations particularly in the context of health system policy-making that is inevitably shared between indigenous communities and jurisdictional or federal governments. Through a mixed methods nominal consensus process, nine values were identified and described: humanity, cultural responsiveness, teaching, nourishment, community voice, kinship, respect, holism and empowerment. PMID:29186925

  20. 'What the hell is water?' How to use deliberate clinical inertia in common emergency department situations.

    PubMed

    Egerton-Warburton, Diana; Cullen, Louise; Keijzers, Gerben; Fatovich, Daniel M

    2018-06-01

    Appropriate deliberate clinical inertia refers to the art of doing nothing as a positive clinical response. It includes shared decision-making to improve patient care with the use of clinical judgement. We discuss common clinical scenarios where the use of deliberate clinical inertia can occur. The insertion of peripheral intravenous cannulae, investigating patients with suspected renal colic and the investigation of low risk chest pain are all opportunities for the thoughtful clinician to 'stand there' and use effective patient communication to avoid low value tests and procedures. Awareness is key to identifying these opportunities to practice deliberate clinical inertia, as many of the situations may be so much a part of our environment that they are hidden in plain view. © 2018 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  1. Shared genetic variance between obesity and white matter integrity in Mexican Americans

    PubMed Central

    Spieker, Elena A.; Kochunov, Peter; Rowland, Laura M.; Sprooten, Emma; Winkler, Anderson M.; Olvera, Rene L.; Almasy, Laura; Duggirala, Ravi; Fox, Peter T.; Blangero, John; Glahn, David C.; Curran, Joanne E.

    2015-01-01

    Obesity is a chronic metabolic disorder that may also lead to reduced white matter integrity, potentially due to shared genetic risk factors. Genetic correlation analyses were conducted in a large cohort of Mexican American families in San Antonio (N = 761, 58% females, ages 18–81 years; 41.3 ± 14.5) from the Genetics of Brain Structure and Function Study. Shared genetic variance was calculated between measures of adiposity [(body mass index (BMI; kg/m2) and waist circumference (WC; in)] and whole-brain and regional measurements of cerebral white matter integrity (fractional anisotropy). Whole-brain average and regional fractional anisotropy values for 10 major white matter tracts were calculated from high angular resolution diffusion tensor imaging data (DTI; 1.7 × 1.7 × 3 mm; 55 directions). Additive genetic factors explained intersubject variance in BMI (heritability, h2 = 0.58), WC (h2 = 0.57), and FA (h2 = 0.49). FA shared significant portions of genetic variance with BMI in the genu (ρG = −0.25), body (ρG = −0.30), and splenium (ρG = −0.26) of the corpus callosum, internal capsule (ρG = −0.29), and thalamic radiation (ρG = −0.31) (all p's = 0.043). The strongest evidence of shared variance was between BMI/WC and FA in the superior fronto-occipital fasciculus (ρG = −0.39, p = 0.020; ρG = −0.39, p = 0.030), which highlights region-specific variation in neural correlates of obesity. This may suggest that increase in obesity and reduced white matter integrity share common genetic risk factors. PMID:25763009

  2. Common Ground on Climate Change: Pairing Opposing Viewpoints for Conversations about Climate Change

    NASA Astrophysics Data System (ADS)

    Kirk, K. B.; Duggan-Haas, D.; Hayhoe, K.

    2017-12-01

    In American public discourse, people tend to strongly identify with the viewpoints held by their cultural and political tribes. However, entrenched positions do little to advance understanding, or work toward solving problems constructively. Worse yet, it has become commonplace to dismiss or demonize those coming from a different point of view - leading to the vitriolic stalemate that often characterizes social media and comment threads when it comes to climate change. One way to break this pattern is to invite people with opposing opinions to actually talk to one another. This presentation describes the lessons learned during the Common Ground on Climate Change project, in which people with contrasting views about climate change engage in a moderated interview with each other. Prior to the interview, participants complete a set of values-based questions. The goal is to reveal areas of common ground between apparent opposites, such as a sense of stewardship for Earth's resources, or an opinion that solutions to climate change will be more beneficial than harmful. The structure of the interviews is based on the hypothesis that if a conversation begins with an appreciation of common values, it becomes easier to broach areas of disagreement. Participants are matched up in one-on-one moderated interviews where they are encouraged to share their concerns, ideas, and priorities about the validity of climate science, the need for urgent action, and the types of solutions they find most tenable. Emerging themes from this series of interviews include the value of a diversity of outlooks, and the ability for moderated conversations to find surprising areas of agreement. Articles about the interviews also appear on the Yale Climate Connections website, https://www.yaleclimateconnections.org/author/karin/.

  3. Examining the etiological associations among higher-order temperament dimensions

    PubMed Central

    Allan, Nicholas P.; Mikolajewski, Amy J.; Lonigan, Christopher J.; Hart, Sara A.; Taylor, Jeanette

    2014-01-01

    A multivariate independent pathway model was used to examine the shared and unique genetic and environmental influences of Positive Affect (PA), Negative Affect (NA), and effortful control (EC) in a sample of 686 twin pairs (M age = 10.07, SD = 1.74). There were common genetic influences and nonshared environmental influences shared across all three temperament dimensions and shared environmental influences in common to NA and EC. There were also significant independent genetic influences unique to PA and NA and significant independent shared environmental influences unique to PA. This study demonstrates that there are genetic and environmental influences that affect the covariance among temperament dimensions as well as unique genetic and environmental influences that influence the dimensions independently. PMID:24729641

  4. The COMPASS Project

    NASA Astrophysics Data System (ADS)

    Duley, A. R.; Sullivan, D.; Fladeland, M. M.; Myers, J.; Craig, M.; Enomoto, F.; Van Gilst, D. P.; Johan, S.

    2011-12-01

    The Common Operations and Management Portal for Airborne Science Systems (COMPASS) project is a multi-center collaborative effort to advance and extend the research capabilities of the National Aeronautics and Space Administration's (NASA) Airborne Science Program (ASP). At its most basic, COMPASS provides tools for visualizing the position of aircraft and instrument observations during the course of a mission, and facilitates dissemination, discussion, and analysis and of multiple disparate data sources in order to more efficiently plan and execute airborne science missions. COMPASS targets a number of key objectives. First, deliver a common operating picture for improved shared situational awareness to all participants in NASA's Airborne Science missions. These participants include scientists, engineers, managers, and the general public. Second, encourage more responsive and collaborative measurements between instruments on multiple aircraft, satellites, and on the surface in order to increase the scientific value of these measurements. Fourth, provide flexible entry points for data providers to supply model and advanced analysis products to mission team members. Fifth, provide data consumers with a mechanism to ingest, search and display data products. Finally, embrace an open and transparent platform where common data products, services, and end user components can be shared with the broader scientific community. In pursuit of these objectives, and in concert with requirements solicited by the airborne science research community, the COMPASS project team has delivered a suite of core tools intended to represent the next generation toolset for airborne research. This toolset includes a collection of loosely coupled RESTful web-services, a system to curate, register, and search, commonly used data sources, end-user tools which leverage web socket and other next generation HTML5 technologies to aid real time aircraft position and data visualization, and an extensible a framework to rapidly accommodate mission specific requirements and mission tools.

  5. Sharing, Privacy and Trust in Our Networked World. A Report to the OCLC Membership

    ERIC Educational Resources Information Center

    Storey, Tom, Ed.

    2007-01-01

    The practice of using a social network to establish and enhance relationships based on some common ground--shared interests, related skills, or a common geographic location--is as old as human societies, but social networking has flourished due to the ease of connecting on the Web. This OCLC membership report explores this web of social…

  6. 78 FR 60348 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... applicant must: (i) Be a Member in good standing of MIAX; (ii) qualify as an ``accredited investor'' as such... each unit (i) 101,695 shares of MIH common stock and (ii) warrants to purchase 2,182,639 shares of common stock of MIH in exchange for such participant Member's initial cash capital contribution of $508...

  7. 2006 Net Centric Operations Conference - Facilitating Net Centric Operations and Warfare

    DTIC Science & Technology

    2006-03-16

    22, 2005 • White Paper, “Facilitating Shared Services in the DoD,” Feb 12, 2006 • White Paper, “ Shared Services : Performance Accountability and Risk...who demand a culture of information sharing and improved organizational effectiveness.” 12 Facilitating Shared Services : Task “What should be the...distinct programs.” 13 Facilitating Shared Services : Focus Areas • Governance and Control Policy • Common Information Standards and Technical

  8. Side effect profile similarities shared between antidepressants and immune-modulators reveal potential novel targets for treating major depressive disorders.

    PubMed

    Sun, Yu; Narayan, Vaibhav A; Wittenberg, Gayle M

    2016-10-21

    Side effects, or the adverse effects of drugs, contain important clinical phenotypic information that may be useful in predicting novel or unknown targets of a drug. It has been suggested that drugs with similar side-effect profiles may share common targets. The diagnostic class, Major Depressive Disorder, is increasingly viewed as being comprised of multiple depression subtypes with different biological root causes. One 'type' of depression generating substantial interest today focuses on patients with high levels of inflammatory burden, indicated by elevated levels of C-reactive proteins (CRP) and pro-inflammatory cytokines such as interleukin 6 (IL-6). It has been suggested that drugs targeting the immune system may have beneficial effect on this subtype of depressed patients, and several studies are underway to test this hypothesis directly. However, patients have been treated with both anti-inflammatory and antidepressant compounds for decades. It may be possible to exploit similarities in clinical readouts to better understand the antidepressant effects of immune-related drugs. Here we explore the space of approved drugs by comparing the drug side effect profiles of known antidepressants and drugs targeting the immune system, and further examine the findings by comparing the human cell line expression profiles induced by them with those induced by antidepressants. We found 7 immune-modulators and 14 anti-inflammatory drugs sharing significant side effect profile similarities with antidepressants. Five of the 7 immune modulators share most similar side effect profiles with antidepressants that modulate dopamine release and/or uptake. In addition, the immunosuppressant rapamycin and the glucocorticoid alclometasone induces transcriptional changes similar to multiple antidepressants. These findings suggest that some antidepressants and some immune-related drugs may affect common molecular pathways. Our findings support the idea that certain medications aimed at the immune system may be helpful in relieving depressive symptoms, and suggest that it may be of value to test immune-modulators for antidepressant-like activity in future proof-of-concept studies.

  9. Open Access to Research Articles and Data: Library Roles

    NASA Astrophysics Data System (ADS)

    Joseph, Heather

    2015-08-01

    Over the past decade, a handful of key developments have caused scholars and researchers to rethink not only the way they conduct their work, but also the way in which they communicate it to others. The advent of the Internet has provided unprecedented opportunities for immediate, cost effective global connectivity, opening up new possibilities for collaboration and communication. This has resulted in scholarship increasingly being conducted in the online environment, and a vast amount of new digital information being generated and made widely available to those interested in using it. Additionally, the Internet is a dynamic environment, with new channels for producing and sharing information in a myriad of formats emerging frequently.In higher education, the momentum of the burgeoning movement towards "open" sharing of information of all kinds continues to gain traction. In particular, advancements in the areas of opening up access to articles and reserch data are increasingly visible. In both of these areas, academic and research libraries are playing important, central roles in promoting the awareness of the potential costs and benefits of a more open research environment, as well as defining new roles for libraries in this digital environment.As this push for grater openness continues, these fronts are intersecting in interesting and potentially transformative ways. The Open Access and Open Data movements share fundamental philosophical commonalities that make collaboration a natural outcome. Both movements place a premium on reducing barriers to discovering and accessing pertinent digital information. Perhaps even more significantly, both explicitly recognize that enabling productive use of digital information is key to unlocking its full value. As a result of these shared priorities, there are a wide variety of common strategies that libraries can take to help advance research, presenting new opportunities for deeper collaboration to take place.This talk will explore what is happening in these "open" movements from both a practical and policy standpoint; how this might directly impact academia, the research community, and especially, libraries.

  10. All inequality is not equal: children correct inequalities using resource value

    PubMed Central

    Shaw, Alex; Olson, Kristina R.

    2013-01-01

    Fairness concerns guide children's judgments about how to share resources with others. However, it is unclear from past research if children take extant inequalities or the value of resources involved in an inequality into account when sharing with others; these questions are the focus of the current studies. In all experiments, children saw an inequality between two recipients—one had two more resources than another. What varied between conditions was the value of the resources that the child could subsequently distribute. When the resources were equal in value to those involved in the original inequality, children corrected the previous inequality by giving two resources to the child with fewer resources (Experiment 1). However, as the value of the resources increased relative to those initially shared by the experimenter, children were more likely to distribute the two high value resources equally between the two recipients, presumably to minimize the overall inequality in value (Experiments 1 and 2). We found that children specifically use value, not just size, when trying to equalize outcomes (Experiment 3) and further found that children focus on the relative rather than absolute value of the resources they share—when the experimenter had unequally distributed the same high value resource that the child would later share, children corrected the previous inequality by giving two high value resources to the person who had received fewer high value resources. These results illustrate that children attempt to correct past inequalities and try to maintain equality not just in the count of resources but also by using the value of resources. PMID:23882227

  11. Plants as models for the study of human pathogenesis.

    PubMed

    Guttman, David S

    2004-05-01

    There are many common disease mechanisms used by bacterial pathogens of plants and humans. They use common means of attachment, secretion and genetic regulation. They share many virulence factors, such as extracellular polysaccharides and some type III secreted effectors. Plant and human innate immune systems also share many similarities. Many of these shared bacterial virulence mechanisms are homologous, but even more appear to have independently converged on a common function. This combination of homologous and analogous systems reveals conserved and critical steps in the disease process. Given these similarities, and the many experimental advantages of plant biology, including ease of replication, stringent genetic and reproductive control, and high throughput with low cost, it is proposed that plants would make excellent models for the study of human pathogenesis.

  12. How Jordan and Saudi Arabia are avoiding a tragedy of the commons over shared groundwater

    NASA Astrophysics Data System (ADS)

    Müller, Marc F.; Müller-Itten, Michèle C.; Gorelick, Steven M.

    2017-07-01

    Transboundary aquifers are ubiquitous and strategically important to global food and water security. Yet these shared resources are being depleted at an alarming rate. Focusing on the Disi aquifer, a key nonrenewable source of groundwater shared by Jordan and Saudi Arabia, this study develops a two-stage game that evaluates optimal transboundary strategies of common-pool resource exploitation under various assumptions. The analysis relies on estimates of agricultural water use from satellite imagery, which were obtained using three independent remote sensing approaches. Drawdown response to pumping is simulated using a 2-D regional aquifer model. Jordan and Saudi Arabia developed a buffer-zone strategy with a prescribed minimum distance between each country's pumping centers. We show that by limiting the marginal impact of pumping decisions on the other country's pumping costs, this strategy will likely avoid an impeding tragedy of the commons for at least 60 years. Our analysis underscores the role played by distance between wells and disparities in groundwater exploitation costs on common-pool overdraft. In effect, if pumping centers are distant enough, a shared aquifer no longer behaves as a common-pool resource and a tragedy of the commons can be avoided. The 2015 Disi aquifer pumping agreement between Jordan and Saudi Arabia, which in practice relies on a joint technical commission to enforce exclusion zones, is the first agreement of this type between sovereign countries and has a promising potential to avoid conflicts or resolve potential transboundary groundwater disputes over comparable aquifer systems elsewhere.

  13. Consumer-perceived value: the key to a successful business strategy in the healthcare marketplace.

    PubMed

    Ettinger, W H

    1998-01-01

    The Medicare market is becoming increasingly competitive and uncertain. To compete successfully for a share of the Medicare market, providers must: Have a cogent strategy that defines their customers and the value proposition for those customers Design their services to maximize the benefits of outcomes and service process that are important to consumers Determine the needed structure and infrastructure to put those services in place Marketing research is critical in this regard, as is effectiveness tracking. This approach is different from that usually taken by healthcare providers in the marketplace. It means being strategic rather than tactical and proactive rather than reactive. Most importantly, providers must shift their focus externally to the consumer's needs rather than their own. Finally, this approach requires working together in an integrated organization with common goals.

  14. [Health education, patient education and health promotion: educational methods and strategies].

    PubMed

    Sandrin, Brigitte

    2013-01-01

    The purpose of this paper is to help public health actors with an interest in health promotion and health care professionals involved in therapeutic education to develop and implement an educational strategy consistent with their vision of health and health care. First, we show that the Ottawa Charter for Health Promotion and the French Charter for Popular Education share common values. Second, an examination of the career and work of Paulo Freire, of Ira Shor's pedagogical model and of the person-centered approach of Carl Rogers shows how the work of educational practitioners, researchers and theorists can help health professionals to implement a truly "health-promoting" or "therapeutic" educational strategy. The paper identifies a number of problems facing health care professionals who become involved in education without reflecting on the values underlying the pedagogical models they use.

  15. Why is data sharing in collaborative natural resource efforts so hard and what can we do to improve it?

    PubMed

    Volk, Carol J; Lucero, Yasmin; Barnas, Katie

    2014-05-01

    Increasingly, research and management in natural resource science rely on very large datasets compiled from multiple sources. While it is generally good to have more data, utilizing large, complex datasets has introduced challenges in data sharing, especially for collaborating researchers in disparate locations ("distributed research teams"). We surveyed natural resource scientists about common data-sharing problems. The major issues identified by our survey respondents (n = 118) when providing data were lack of clarity in the data request (including format of data requested). When receiving data, survey respondents reported various insufficiencies in documentation describing the data (e.g., no data collection description/no protocol, data aggregated, or summarized without explanation). Since metadata, or "information about the data," is a central obstacle in efficient data handling, we suggest documenting metadata through data dictionaries, protocols, read-me files, explicit null value documentation, and process metadata as essential to any large-scale research program. We advocate for all researchers, but especially those involved in distributed teams to alleviate these problems with the use of several readily available communication strategies including the use of organizational charts to define roles, data flow diagrams to outline procedures and timelines, and data update cycles to guide data-handling expectations. In particular, we argue that distributed research teams magnify data-sharing challenges making data management training even more crucial for natural resource scientists. If natural resource scientists fail to overcome communication and metadata documentation issues, then negative data-sharing experiences will likely continue to undermine the success of many large-scale collaborative projects.

  16. Why is Data Sharing in Collaborative Natural Resource Efforts so Hard and What can We Do to Improve it?

    NASA Astrophysics Data System (ADS)

    Volk, Carol J.; Lucero, Yasmin; Barnas, Katie

    2014-05-01

    Increasingly, research and management in natural resource science rely on very large datasets compiled from multiple sources. While it is generally good to have more data, utilizing large, complex datasets has introduced challenges in data sharing, especially for collaborating researchers in disparate locations ("distributed research teams"). We surveyed natural resource scientists about common data-sharing problems. The major issues identified by our survey respondents ( n = 118) when providing data were lack of clarity in the data request (including format of data requested). When receiving data, survey respondents reported various insufficiencies in documentation describing the data (e.g., no data collection description/no protocol, data aggregated, or summarized without explanation). Since metadata, or "information about the data," is a central obstacle in efficient data handling, we suggest documenting metadata through data dictionaries, protocols, read-me files, explicit null value documentation, and process metadata as essential to any large-scale research program. We advocate for all researchers, but especially those involved in distributed teams to alleviate these problems with the use of several readily available communication strategies including the use of organizational charts to define roles, data flow diagrams to outline procedures and timelines, and data update cycles to guide data-handling expectations. In particular, we argue that distributed research teams magnify data-sharing challenges making data management training even more crucial for natural resource scientists. If natural resource scientists fail to overcome communication and metadata documentation issues, then negative data-sharing experiences will likely continue to undermine the success of many large-scale collaborative projects.

  17. Identifying Shared Values for School-Affiliated Student Organizations

    PubMed Central

    Bush, Antonio A.; Buhlinger, Kaitlyn M.

    2017-01-01

    Objective. To identify shared values for student organizations. Methods. A three-round Delphi approach was utilized to identify and prioritize shared values among student organization leadership. In round 1, student leaders selected 15 values from a list of 36 organizational values and were given an opportunity to include up to five suggestions not incorporated within the original list. Student leaders narrowed the 15 values to 12 in round 2. The top 12 priorities were ranked in round 3 and participants were invited to write a brief statement regarding their perspectives of the results. Results. Twelve shared values were identified and ranked: professional development, improving leadership of your members, advancing the role of pharmacy, planning quality events, networking, improving the academic experience for peers, community service, learning from pharmacy shadowing/speakers, social outlet, recruitment/gaining student membership, attracting students to events, and gaining national/local attention or awards. Conclusion. This study contributes to the small but growing body of literature concerning student organizations in pharmacy education and provides a foundation by which this work could be advanced. Given the importance of student organizations in promoting student development, identifying strategies for supporting and facilitating the effectiveness of these groups is critical for optimizing student outcomes and institutional effectiveness. PMID:29302089

  18. A moral compass for management decision making: a healthcare CEO's reflections.

    PubMed

    Donnellan, John J

    2013-01-01

    Ethical behavior is good for business in any organization. In healthcare, it results in better patient care, a more committed and satisfied staff, more efficient care delivery, and increased market share. But it requires leaders who have a broad view of the role that ethics programs--and an effective, sustained ethical culture--play. Ethical organizations have integrated and shared ethical values and practices, an effective ethics infrastructure, ongoing ethics education for staff at every level, ethical and morally courageous leaders, and a culture that is consistent with the organization's values. The mission, vision, and values statements of these organizations have been successfully translated into a set of shared values--a moral compass that guides behavior and decision making.

  19. 50 CFR 85.40 - Cost sharing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Use/Acceptance of Funds § 85.40 Cost sharing. (a) The Federal share shall not exceed 75% of total... grant objectives and represent the current market value of noncash contributions furnished as part of...

  20. Therapists' thoughts on therapy: clinicians' perceptions of the therapy processes that distinguish schema, cognitive behavioural and psychodynamic approaches.

    PubMed

    Boterhoven De Haan, Katrina L; Lee, Christopher W

    2014-01-01

    Debates continue over shared factors in therapy processes between different theoretical orientations. By seeking the opinions of practicing clinicians, this study aimed to elucidate the similarities and differences between cognitive-behavioural (CBT), psychodynamic (PDT), and schema therapy (ST) approaches. Forty-eight practitioners aligning with one of the three approaches were asked to identify crucial processes in their therapy using a modified online version of the Psychotherapy Process Q-set. Distinct differences between each theoretical orientation with few shared common factors were found. A comparison with ratings from previous studies indicated that CBT therapists have not changed over the last 20 years, whereas PDT therapists have changed and the differences appeared consistent with modern PDT theory. The differences between the therapy approaches were consistent with theories underlying each model. PDT therapists valued a neutral relationship, CBT therapists emphasized a didactic interaction, and therapists form a ST orientation placed a greater emphasis on emotional involvement.

  1. Should intellectual property be disseminated by "forwarding" rejected letters without permission?

    PubMed

    Gupta, V K

    1996-08-01

    Substantive scientific letter writing is a cost-effective mode of complementing observational and experimental research. The value of such philosophically uncommitted and unsponsored well-balanced scientific activity has been relegated. Critical letter writing entails the abilities to: maintain rational scepticism; refuse to conform in order to explain data; persist in keeping common sense centre-stage; exercise logic to evaluate the biological significance of mathematical figures, including statistics, and the ability to sustain the will to share insights regarding disease mechanisms on an ostensibly lower research platform. During peer review, innovative letter writing may share the occasionally unfortunate fate of innovative research. Rejected scientific letters do not automatically lose copyright. Periodicals with high letter loads will see some valuable contributions wasted, but that is the price for maintaining autonomy in scientific publication. The scientific community is an integrated whole that must respect the rights of authors at all levels. Unauthorised forwarding of rejected letters sets the dangerous precedent of justifying unjust means.

  2. Finding an appropriate ethic in a world of moral acquaintances.

    PubMed

    Loewy, E H

    1997-01-01

    This paper discusses the possibility of finding an ethic of at least partial and perhaps ever-growing content in a world not that of moral strangers (where we have nothing except our desire to live freely to unite us) and one of moral friends (in which values, goals and ways of doing things are held in common). I argue that both the world of moral strangers which Engelhardt's world view would support, as the world of moral friends which is the one Pellegrino seeks both are untenable and that furthermore both can lead to a similar state of affairs. I suggest a dynamic world of moral acquaintances in which different belief systems and ways of doing things can come to some broad agreements about some essential thing. This is made possible because although we do not share the intimate framework Pellegrino might suggest, yet we are united by a much broader framework than the one moral strangers share.

  3. Who Supports the Successful Implementation and Sustainability of Evidence-Based Practices? Defining and Understanding the Roles of Intermediary and Purveyor Organizations.

    PubMed

    Franks, Robert P; Bory, Christopher T

    2015-01-01

    Research on implementation science has increased significantly over the past decade. In particular, psychologists have looked closely at the value and importance of bridging the gap between science and practice. As evidence-based practices (EBPs) become more prevalent, concrete mechanisms are needed to bring these scientifically supported treatments and interventions to community-based settings. Intermediary and purveyor organizations (IPOs) have emerged in recent years that specialize in bringing research to practice. Using a framework developed by Franks (), this descriptive study surveyed respondents that self-identified as IPOs and focused on identifying shared definitions, functions, and activities. Results indicated that seven descriptive roles previously identified were supported by this survey and many common shared activities, goals, and functions across these organizations were observed. Further, these organizations appear to be influenced by the growing field of implementation science. Limitations and implications of this study are discussed. © 2015 Wiley Periodicals, Inc.

  4. The Currency of Consciousness: Neurology, Specialization, and the Global Practices of Medicine.

    PubMed

    Casper, Stephen T

    2016-01-01

    This article explores the formation of a global community of neurologists between 1918 and 1970. Relying chiefly upon documents located in Anglo-American archives, its argument follows a narrative from money to memory, and posits that this global community of neurologists formed not out of a shared science and medicine of the nervous system, but out of shared dispositions in tastes, values, and culture. The localism and heterogeneity of the science and medicine of the nervous system was in fact so pronounced that neurologists - especially when they worked as "global citizens" - were forced to focus upon their superficial commonalities rather than examine local distinctions. This avoidance of a direct effort to define the content of neurology - or at least to confront their differences - exercised a peculiar influence on the specialty. Neurologists and their "official memory" became negotiated, and even imagined constructs. Consequently, these diverse cultures were ultimately subordinated to dominant economic interests.

  5. The science commons in health research: structure, function, and value.

    PubMed

    Cook-Deegan, Robert

    The "science commons," knowledge that is widely accessible at low or no cost, is a uniquely important input to scientific advance and cumulative technological innovation. It is primarily, although not exclusively, funded by government and nonprofit sources. Much of it is produced at academic research centers, although some academic science is proprietary and some privately funded R&D enters the science commons. Science in general aspires to Mertonian norms of openness, universality, objectivity, and critical inquiry. The science commons diverges from proprietary science primarily in being open and being very broadly available. These features make the science commons particularly valuable for advancing knowledge, for training innovators who will ultimately work in both public and private sectors, and in providing a common stock of knowledge upon which all players-both public and private-can draw readily. Open science plays two important roles that proprietary R&D cannot: it enables practical benefits even in the absence of profitable markets for goods and services, and its lays a shared foundation for subsequent private R&D. The history of genomics in the period 1992-2004, covering two periods when genomic startup firms attracted significant private R&D investment, illustrates these features of how a science commons contributes value. Commercial interest in genomics was intense during this period. Fierce competition between private sector and public sector genomics programs was highly visible. Seemingly anomalous behavior, such as private firms funding "open science," can be explained by unusual business dynamics between established firms wanting to preserve a robust science commons to prevent startup firms from limiting established firms' freedom to operate. Deliberate policies to create and protect a large science commons were pursued by nonprofit and government funders of genomics research, such as the Wellcome Trust and National Institutes of Health. These policies were crucial to keeping genomic data and research tools widely available at low cost.

  6. Space Sharing Between Formal and Informal Sectors In Kemang Area

    NASA Astrophysics Data System (ADS)

    Sihombing, Antony; Dewanti, Hafizka Chandra

    2018-01-01

    Sharing is a form of human activity as a social being, over resources or spaces. Humans generally define their space according to their psychological and biological needs. However, what if space sharing takes place in an urban scope? The phenomenon of space sharing happens in Kemang area done by two distinct sectors, formal and informal which both are engaged in commercial activities independently. In the study of territory and the behavior settings, the quality of environment can affect the formation of human activities in a space, occurs a phenomenon of space sharing. The researcher will discuss and present a form of the space sharing by the formal and informal sectors in a commercial area through different environmental qualities. In some circumstance, a form of space sharing can increase the value of space and obtain to a shared space, where both sectors mutually take benefits. Otherwise, it leads to an adverse impact in some others. It is clear that differences in the physical environment and social environment have an impact on the formation of space sharing and the value of space in an urban region.

  7. Job Sharing: Is It for You?

    ERIC Educational Resources Information Center

    Schumann, Linda

    1994-01-01

    A teacher of deaf children describes her experience with job sharing at both the intermediate grade and preschool levels. The important role played by the full-time teacher's aide in providing continuity as well as the importance of communication are emphasized. Guidelines and answers to common questions regarding job sharing are offered. (DB)

  8. 26 CFR 1.356-2 - Receipt of additional consideration not in connection with an exchange.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shares of the stock of Corporation Y plus $100 cash without requiring the surrender of any shares of its... stock of Corporation Y to A and 30 shares of such stock plus $100 cash to B without requiring the.... Individuals A and B each own 50 of the 100 outstanding shares of common stock of Corporation X. Corporation X...

  9. The Great American Divide: The Military-Civilian Gap

    DTIC Science & Technology

    2012-03-14

    for the common defense … do ordain and establish this Constitution for the United States of America .”1 Such are the words to... and “provide for the common defense ” that enshrine the idea of shared sacrifice among all the American people in protecting and defending the ...United States. For much of the United States’ history, this idea of shared sacrifice in the

  10. Fair Share or Freeride: Burden Sharing in Post-Cold War NATO

    DTIC Science & Technology

    2015-05-23

    military facilities in Europe. 56 Carl Elk, NATO Common Funds Burdensharing: Background and Current Issues (Washington DC: Congressional Research...Defense Minister Franz Joseph Jung replied, “our contribution is excellent.”114 Germany was clearly proud of its contribution to NATO operations, but...Monsanto, Portugal: NATO Joint Analysis Lessons Learned Centre (JALLC), 2011. Elk, Carl . NATO Common Funds Burdensharing: Background and Current

  11. Clusters of cultures: diversity in meaning of family value and gender role items across Europe.

    PubMed

    van Vlimmeren, Eva; Moors, Guy B D; Gelissen, John P T M

    2017-01-01

    Survey data are often used to map cultural diversity by aggregating scores of attitude and value items across countries. However, this procedure only makes sense if the same concept is measured in all countries. In this study we argue that when (co)variances among sets of items are similar across countries, these countries share a common way of assigning meaning to the items. Clusters of cultures can then be observed by doing a cluster analysis on the (co)variance matrices of sets of related items. This study focuses on family values and gender role attitudes. We find four clusters of cultures that assign a distinct meaning to these items, especially in the case of gender roles. Some of these differences reflect response style behavior in the form of acquiescence. Adjusting for this style effect impacts on country comparisons hence demonstrating the usefulness of investigating the patterns of meaning given to sets of items prior to aggregating scores into cultural characteristics.

  12. The religious foundations of health care: a conceptual approach.

    PubMed Central

    Sevensky, R L

    1983-01-01

    The relationship of religion and health is often misunderstood owing to a tendency to concentrate on the medical model and to ignore the wider context of heath care. A conceptual--as opposed to a historical--examination of this context reveals nine central religious ideas or categories which provide an ethical foundation and heritage for medical practice and health care delivery. These include doctrines of creation; dominion or stewardship; freedom and responsibility; human dignity or sanctity of life; love or compassion; covenant; justice; vocation; and finitude. A discussion of the complementarity of religion and medicine is necessary and should proceed from these shared values and common concerns. PMID:6620322

  13. Removing Hair Safely

    MedlinePlus

    ... For Consumers Home For Consumers Consumer Updates Removing Hair Safely Share Tweet Linkedin Pin it More sharing ... related to common methods of hair removal. Laser Hair Removal In this method, a laser destroys hair ...

  14. Semantic similarity measurement between gene ontology terms based on exclusively inherited shared information.

    PubMed

    Zhang, Shu-Bo; Lai, Jian-Huang

    2015-03-01

    Quantifying the semantic similarities between pairs of terms in the Gene Ontology (GO) structure can help to explore the functional relationships between biological entities. A common approach to this problem is to measure the information they have in common based on the information content of their common ancestors. However, many studies have their limitations in measuring the information two GO terms share. This study presented a new measurement, exclusively inherited shared information (EISI) that captured the information shared by two terms based on an intuitive observation on the multiple inheritance relationships among the terms in the GO graph. EISI was derived from the information content of the exclusively inherited common ancestors (EICAs), which were screened from the common ancestors according to the attribute of their direct children. The effectiveness of EISI was evaluated against some state-of-the-art measurements on both artificial and real datasets, it produced more relevant results with experts' scores on the artificial dataset, and supported the prior knowledge of gene function in pathways on the Saccharomyces genome database (SGD). The promising features of EISI are the following: (1) it provides a more effective way to characterize the semantic relationship between two GO terms by taking into account multiple common ancestors related, and (2) can quickly detect all EICAs with time complexity of O(n), which is much more efficient than other methods based on disjunctive common ancestors. It is a promising alternative to multiple inheritance based methods for practical applications on large-scale dataset. The algorithm EISI was implemented in Matlab and is freely available from http://treaton.evai.pl/EISI/. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. "Shall I Tell You a Story?" Sharing Love and Values through Storytelling.

    ERIC Educational Resources Information Center

    Collins, Chase

    1992-01-01

    Parents can share love and values with their children through story telling. Because parents know their children intimately, they can create stories that impact their children's developing minds most effectively. The article describes how to create a classic tale in less than 10 minutes. (SM)

  16. 29 CFR 95.23 - Cost sharing or matching.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the.... (g) The method used for determining cost sharing or matching for donated equipment, buildings and... in the acquisition of equipment, buildings or land, the total value of the donated property may be...

  17. 22 CFR 518.23 - Cost sharing or matching.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... applicable cost principles. If a Federal awarding agency authorizes recipients to donate buildings or land for construction/facilities acquisition projects or long-term use, the value of the donated property...

  18. 22 CFR 518.23 - Cost sharing or matching.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... applicable cost principles. If a Federal awarding agency authorizes recipients to donate buildings or land for construction/facilities acquisition projects or long-term use, the value of the donated property...

  19. 29 CFR 95.23 - Cost sharing or matching.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the.... (g) The method used for determining cost sharing or matching for donated equipment, buildings and... in the acquisition of equipment, buildings or land, the total value of the donated property may be...

  20. 29 CFR 95.23 - Cost sharing or matching.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the.... (g) The method used for determining cost sharing or matching for donated equipment, buildings and... in the acquisition of equipment, buildings or land, the total value of the donated property may be...

  1. 29 CFR 95.23 - Cost sharing or matching.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the.... (g) The method used for determining cost sharing or matching for donated equipment, buildings and... in the acquisition of equipment, buildings or land, the total value of the donated property may be...

  2. 22 CFR 518.23 - Cost sharing or matching.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... applicable cost principles. If a Federal awarding agency authorizes recipients to donate buildings or land for construction/facilities acquisition projects or long-term use, the value of the donated property...

  3. 22 CFR 518.23 - Cost sharing or matching.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... applicable cost principles. If a Federal awarding agency authorizes recipients to donate buildings or land for construction/facilities acquisition projects or long-term use, the value of the donated property...

  4. 29 CFR 95.23 - Cost sharing or matching.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... buildings or land for construction/facilities acquisition projects or long-term use, the value of the.... (g) The method used for determining cost sharing or matching for donated equipment, buildings and... in the acquisition of equipment, buildings or land, the total value of the donated property may be...

  5. 22 CFR 518.23 - Cost sharing or matching.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., buildings or land, the total value of the donated property may be claimed as cost sharing or matching. (2... applicable cost principles. If a Federal awarding agency authorizes recipients to donate buildings or land for construction/facilities acquisition projects or long-term use, the value of the donated property...

  6. 48 CFR 48.104 - Sharing arrangements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Sharing arrangements. 48.104 Section 48.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT VALUE ENGINEERING Policies and Procedures 48.104 Sharing arrangements. ...

  7. The Common Sense of Small Nuclear Arsenals

    DTIC Science & Technology

    2012-01-01

    affairs. That pattern is continuing and, therefore, is worth examining. In this article I use structural theory to explain what I call “the com­ mon...deterrence and dis­ suasion and then explain small nuclear arsenals in terms of structural theory , relying most heavily on the effects of socialization...deterrence are particularly useful. Dissuasion and general deterrence share many common elements. Both are rooted in deterrence theory and share an

  8. Application of a Socio-Ecological Model to Mother-Infant Bed-Sharing

    ERIC Educational Resources Information Center

    Salm Ward, Trina C.; Doering, Jennifer J.

    2014-01-01

    Mother-infant bed-sharing has been associated with an increased risk of sleep-related infant deaths, and thus, health messaging has aimed to discourage this behavior. Despite this messaging, bed-sharing remains a common practice in the United States, especially among minority families. Moreover, rates of accidental suffocation and strangulation in…

  9. Boeing’s Integrated Defense Systems Restructuring: Significant and Preventable Cost Impacts to Army Aviation Programs

    DTIC Science & Technology

    2005-03-18

    IDS, the treatment and handling of Boeing World Headquarters (BWHQ) costs, common or shared systems costs, Shared Services Group costs, fringe...these expenses.15 One such example is the addition of the Shared Services Group (SSG) expense to the Mesa and Philadelphia accounting ledgers. Under

  10. Why use group visits for opioid use disorder treatment in primary care? A patient-centered qualitative study.

    PubMed

    Sokol, Randi; Albanese, Chiara; Chaponis, Deviney; Early, Jessica; Maxted, George; Morrill, Diana; Poirier, Grace; Puopolo, Fran; Schuman-Olivier, Zev

    2018-01-02

    Primary care providers are well positioned to respond to the opioid crisis by providing buprenorphine/naloxone (B/N) through shared medical appointments (SMAs). Although quantitative research has been previously conducted on SMAs with B/N, the authors conducted a qualitative assessment from the patients' point of view, considering whether and how group visits provide value for patients. Twenty-five participants with opioid use disorder (OUD) who were enrolled in a weekly B/N group visit at a family medicine clinic participated in either of two 1-hour-long focus groups, which were conducted as actual group visits. Participants were prompted with the question "How has this group changed you as a person?" Data were audio-recorded and professionally transcribed and analyzed using a qualitative thematic approach, identifying common communication behaviors and resulting attitudes about the value of the group visit model. Participants demonstrated several communication behaviors that support group members in their recovery, including offering direct emotional support to others struggling with difficult experiences, making an intentional effort to probe about others' lives, venting about heavy situations, joking to lighten the mood, and expressing feelings of gratitude to the entire group. These communication behaviors appear to act as mechanisms to foster a sense of accountability, a shared identity, and a supportive community. Other demonstrated group behaviors may detract from the value of the group experience, including side conversations, tangential comments, and individual participants disproportionately dominating group time. The group visit format for delivering B/N promotes group-specific communication behaviors that may add unique value in supporting patients in their recovery. Future research should elucidate whether these benefits can be isolated from those achieved solely through medication treatment with B/N and if similar benefits could be achieved in non-primary care sites.

  11. A national-scale authentication infrastructure.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Butler, R.; Engert, D.; Foster, I.

    2000-12-01

    Today, individuals and institutions in science and industry are increasingly forming virtual organizations to pool resources and tackle a common goal. Participants in virtual organizations commonly need to share resources such as data archives, computer cycles, and networks - resources usually available only with restrictions based on the requested resource's nature and the user's identity. Thus, any sharing mechanism must have the ability to authenticate the user's identity and determine if the user is authorized to request the resource. Virtual organizations tend to be fluid, however, so authentication mechanisms must be flexible and lightweight, allowing administrators to quickly establish andmore » change resource-sharing arrangements. However, because virtual organizations complement rather than replace existing institutions, sharing mechanisms cannot change local policies and must allow individual institutions to maintain control over their own resources. Our group has created and deployed an authentication and authorization infrastructure that meets these requirements: the Grid Security Infrastructure. GSI offers secure single sign-ons and preserves site control over access policies and local security. It provides its own versions of common applications, such as FTP and remote login, and a programming interface for creating secure applications.« less

  12. Data Rights and Responsibilities: A Human Rights Perspective on Data Sharing.

    PubMed

    Harris, Theresa L; Wyndham, Jessica M

    2015-07-01

    A human-rights-based analysis can be a useful tool for the scientific community and policy makers as they develop codes of conduct, harmonized standards, and national policies for data sharing. The human rights framework provides a shared set of values and norms across borders, defines rights and responsibilities of various actors involved in data sharing, addresses the potential harms as well as the benefits of data sharing, and offers a framework for balancing competing values. The right to enjoy the benefits of scientific progress and its applications offers a particularly helpful lens through which to view data as both a tool of scientific inquiry to which access is vital and as a product of science from which everyone should benefit. © The Author(s) 2015.

  13. Facile Growth of High-Yield Gold Nanobipyramids Induced by Chloroplatinic Acid for High Refractive Index Sensing Properties.

    PubMed

    Fang, Caihong; Zhao, Guili; Xiao, Yanling; Zhao, Jun; Zhang, Zijun; Geng, Baoyou

    2016-11-14

    Au nanobipyramids (NBPs) have attracted great attention because of their unique localized surface plasmon resonance properties. However, the current growth methods always have low yield or suffer tedious process. Developing new ways to direct synthesis of high-yield Au NBPs using common agents is therefore desirable. Here, we employed chloroplatinic acid as the key shape-directing agent for the first time to grow Au NBPs using a modified seed-mediated method at room temperature. H 2 PtCl 6 was added both during the seed preparation and in growth solution. Metallic Pt, reduced from chloroplatinic acid, will deposit on the surface of the seed nanoparticles and the Au nanocrystals and thus plays a critical role for the formation of Au NBPs. Additionally, the reductant, precursor, and surfactant are all cheap and commonly used. Furthermore, the Au NBPs offer narrow size distribution, two sharp tips, and a shared basis. Au NBPs therefore show much higher refractive index sensitivities than that of the Au nanorods. The refractive index sensitivities and lager figure of merit values of Au NBPs exhibit an increase of 63% and 321% respectively compared to the corresponding values of Au nanorod sample.

  14. Innovation in qualitative interviews: "Sharing Circles" in a First Nations community.

    PubMed

    Rothe, J P; Ozegovic, D; Carroll, L J

    2009-10-01

    There is growing recognition that different research approaches are necessary to understand the complex interaction between individual and social processes that contribute to risk-taking and injuries. Therefore, qualitative studies have an important role in injury prevention research. This article describes qualitative research in general and outlines some of the ways qualitative research can add to our understanding of injury. It also describes the role, format and methods of interviews (person-to-person and focus groups) commonly performed in qualitative studies, and proposes a novel approach to interviewing that has special relevance and value in injury research with indigenous populations. This methodology adapts focus group methods to be consistent with the goals and procedures of the traditional First Nations communities' Sharing Circles. This adaptation provides a culturally appropriate and sensitive method of developing a deep and broad understanding of indigenous participants' verbal descriptions of their feelings, their experiences and their modes of reasoning. After detailing of this adaptation of the Sharing Circle as a vibrant and vital interview and analysis method, the use of Sharing Circle interview methodology will be illustrated in a study investigating how an Alberta First Nations community experiences and deals with disproportionate levels of injuries arising from impaired driving, outlining important findings uncovered using this novel interviewing method. These findings have been informative to First Nations communities themselves, have informed policy makers provincially and nationally, and have instigated culturally appropriate intervention techniques for Canadian First Nations communities.

  15. The Value of Medicines: A Crucial but Vague Concept.

    PubMed

    Antoñanzas, Fernando; Terkola, Robert; Postma, Maarten

    2016-12-01

    Health Technology Assessment is increasingly used to evaluate the value of healthcare products and to prioritize resources; however, defining exactly what value is and how it should be measured remains a challenge. In this article, we report the results of a literature review, focusing on nine European countries, with the aim of investigating how value is defined from the perspective of different stakeholders, how definitions of value are used, and how value is incorporated into decision making. Only three articles were identified that presented definitions of value, and there was no single shared definition of value in healthcare, which appears to be a highly subjective concept. The majority of the countries investigated combine clinical assessment with economic evaluation to make reimbursement recommendations; the quality-adjusted life-year is the most commonly used measure of value but does not capture broader aspects of value that may be important to patients and healthcare systems. We describe the use of value-based pricing and multi-criteria decision analysis, two approaches to the incorporation of broader aspects of value into decision making. Overall, we have identified considerable variation in how a product's value is defined by different stakeholders. Although a universal understanding of value in healthcare is important, it is clear that current definitions are insufficient, potentially leading to inconsistent reimbursement decisions. Ultimately, the establishment of clearer policies for defining and measuring value in healthcare is needed, and is likely to lead to improvements in the consistency of decision making.

  16. Simple Shared Motifs (SSM) in conserved region of promoters: a new approach to identify co-regulation patterns.

    PubMed

    Gruel, Jérémy; LeBorgne, Michel; LeMeur, Nolwenn; Théret, Nathalie

    2011-09-12

    Regulation of gene expression plays a pivotal role in cellular functions. However, understanding the dynamics of transcription remains a challenging task. A host of computational approaches have been developed to identify regulatory motifs, mainly based on the recognition of DNA sequences for transcription factor binding sites. Recent integration of additional data from genomic analyses or phylogenetic footprinting has significantly improved these methods. Here, we propose a different approach based on the compilation of Simple Shared Motifs (SSM), groups of sequences defined by their length and similarity and present in conserved sequences of gene promoters. We developed an original algorithm to search and count SSM in pairs of genes. An exceptional number of SSM is considered as a common regulatory pattern. The SSM approach is applied to a sample set of genes and validated using functional gene-set enrichment analyses. We demonstrate that the SSM approach selects genes that are over-represented in specific biological categories (Ontology and Pathways) and are enriched in co-expressed genes. Finally we show that genes co-expressed in the same tissue or involved in the same biological pathway have increased SSM values. Using unbiased clustering of genes, Simple Shared Motifs analysis constitutes an original contribution to provide a clearer definition of expression networks.

  17. Simple Shared Motifs (SSM) in conserved region of promoters: a new approach to identify co-regulation patterns

    PubMed Central

    2011-01-01

    Background Regulation of gene expression plays a pivotal role in cellular functions. However, understanding the dynamics of transcription remains a challenging task. A host of computational approaches have been developed to identify regulatory motifs, mainly based on the recognition of DNA sequences for transcription factor binding sites. Recent integration of additional data from genomic analyses or phylogenetic footprinting has significantly improved these methods. Results Here, we propose a different approach based on the compilation of Simple Shared Motifs (SSM), groups of sequences defined by their length and similarity and present in conserved sequences of gene promoters. We developed an original algorithm to search and count SSM in pairs of genes. An exceptional number of SSM is considered as a common regulatory pattern. The SSM approach is applied to a sample set of genes and validated using functional gene-set enrichment analyses. We demonstrate that the SSM approach selects genes that are over-represented in specific biological categories (Ontology and Pathways) and are enriched in co-expressed genes. Finally we show that genes co-expressed in the same tissue or involved in the same biological pathway have increased SSM values. Conclusions Using unbiased clustering of genes, Simple Shared Motifs analysis constitutes an original contribution to provide a clearer definition of expression networks. PMID:21910886

  18. Promoting Shared Decision Making in Disorders of Sex Development (DSD): Decision Aids and Support Tools.

    PubMed

    Siminoff, L A; Sandberg, D E

    2015-05-01

    Specific complaints and grievances from adult patients with disorders of sex development (DSD), and their advocates center around the lack of information or misinformation they were given about their condition and feeling stigmatized and shamed by the secrecy surrounding their condition and its management. Many also attribute poor sexual function to damaging genital surgery and/or repeated, insensitive genital examinations. These reports suggest the need to reconsider the decision-making process for the treatment of children born with DSD. This paper proposes that shared decision making, an important concept in adult health care, be operationalized for the major decisions commonly encountered in DSD care and facilitated through the utilization of decision aids and support tools. This approach may help patients and their families make informed decisions that are better aligned with their personal values and goals. It may also lead to greater confidence in decision making with greater satisfaction and less regret. A brief review of the past and current approach to DSD decision making is provided, along with a review of shared decision making and decision aids and support tools. A case study explores the need and potential utility of this suggested new approach. © Georg Thieme Verlag KG Stuttgart · New York.

  19. What Are Some Common Signs of Pregnancy?

    MedlinePlus

    ... pregnancy? Share Facebook Twitter Pinterest Email Print What are some common signs of pregnancy? The primary sign ... always mean a woman is pregnant. Menstrual irregularities are common and can have a variety of causes, ...

  20. Identification of genetic loci shared between schizophrenia and the Big Five personality traits.

    PubMed

    Smeland, Olav B; Wang, Yunpeng; Lo, Min-Tzu; Li, Wen; Frei, Oleksandr; Witoelar, Aree; Tesli, Martin; Hinds, David A; Tung, Joyce Y; Djurovic, Srdjan; Chen, Chi-Hua; Dale, Anders M; Andreassen, Ole A

    2017-05-22

    Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between schizophrenia and the Big Five personality traits using a Bayesian statistical framework. Using summary statistics from genome-wide association studies (GWAS) on personality traits in the 23andMe cohort (n = 59,225) and schizophrenia in the Psychiatric Genomics Consortium cohort (n = 82,315), we evaluated overlap in common genetic variants. The Big Five personality traits neuroticism, extraversion, openness, agreeableness and conscientiousness were measured using a web implementation of the Big Five Inventory. Applying the conditional false discovery rate approach, we increased discovery of genetic loci and identified two loci shared between neuroticism and schizophrenia and six loci shared between openness and schizophrenia. The study provides new insights into the relationship between personality traits and schizophrenia by highlighting genetic loci involved in their common genetic etiology.

  1. Food Sharing across Borders : First Observation of Intercommunity Meat Sharing by Bonobos at LuiKotale, DRC.

    PubMed

    Fruth, Barbara; Hohmann, Gottfried

    2018-06-01

    Evolutionary models consider hunting and food sharing to be milestones that paved the way from primate to human societies. Because fossil evidence is scarce, hominoid primates serve as referential models to assess our common ancestors' capacity in terms of communal use of resources, food sharing, and other forms of cooperation. Whereas chimpanzees form male-male bonds exhibiting resource-defense polygyny with intolerance and aggression toward nonresidents, bonobos form male-female and female-female bonds resulting in relaxed relations with neighboring groups. Here we report the first known case of meat sharing between members of two bonobo communities, revealing a new dimension of social tolerance in this species. This observation testifies to the behavioral plasticity that exists in the two Pan species and contributes to scenarios concerning the traits of the last common ancestor of Pan and Homo. It also contributes to the discussion of physiological triggers of in-group/out-group behavior and allows reconsideration of the emergence of social norms in prehuman societies.

  2. This presentation will discuss how PLOS ONE collaborates with many different scientific communities to help create, share, and preserve the scholarly works produced by their researchers with emphasis on current common difficulties faced by communities, practical solutions, and a broader view of the importance of open data and reproducibility.

    NASA Astrophysics Data System (ADS)

    Kroffe, K.

    2017-12-01

    The mission of the Public Library of Science is to accelerate progress in science and medicine by leading a transformation in research communication. Researchers' ability to share their work without restriction is essential, but critical to sharing is open data, transparency in peer review, and an open approach to science assessment. In this session, we will discuss how PLOS ONE collaborates with many different scientific communities to help create, share, and preserve the scholarly works produced by their researchers with emphasis on current common difficulties faced by communities, practical solutions, and a broader view of the importance of open data and reproducibility.

  3. Negotiating treatment preferences: Physicians' formulations of patients' stance.

    PubMed

    Landmark, Anne Marie Dalby; Svennevig, Jan; Gulbrandsen, Pål

    2016-01-01

    Eliciting patients' values and treatment preferences is an essential element in models of shared decision making, yet few studies have investigated the interactional realizations of how physicians do this in authentic encounters. Drawing on video-recorded encounters from Norwegian secondary care, the present study uses the fine-grained empirical methodology of conversation analysis (CA) to identify one conversational practice physicians use, namely, formulations of patients' stance, in which physicians summarize or paraphrase their understanding of the patient's stance towards treatment. The purpose of this study is twofold: (1) to explore what objectives formulations of patients' stance achieve while negotiating treatment and (2) to discuss these objectives in relation to core requirements in shared decision making. Our analysis demonstrates that formulating the patient's stance is a practice physicians use in order to elicit, check, and establish patients' attitudes towards treatment. This practice is in line with general recommendations for making shared decisions, such as exploring and checking patients' preferences and values. However, the formulations may function as a device for doing more than merely checking and establishing common ground and bringing up patients' preferences and views: Accompanied by subtle deprecating expressions, they work to delegitimize the patients' stances and indirectly convey the physicians' opposing stance. Once established, these positions can be used as a basis for challenging and potentially altering the patient's attitude towards the decision, thereby making it more congruent with the physician's view. Therefore, in addition to bringing up patients' views towards treatment, we argue that physicians may use formulations of patients' stance as a resource for directing the patient towards decisions that are congruent with the physician's stance in situations with potential disagreement, whilst (ostensibly) avoiding a more authoritarian or paternalistic approach. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Stock or cash? The trade-offs for buyers and sellers in mergers and acquisitions.

    PubMed

    Rappaport, A; Sirower, M L

    1999-01-01

    In 1988, less than 2% of large deals were paid for entirely in stock; by 1998, that number had risen to 50%. The shift has profound ramifications for shareholders of both the acquiring and acquired companies. In this article, the authors provide a framework and two simple tools to guide boards of both companies through the issues they need to consider when making decisions about how to pay for--and whether to accept--a deal. First an acquirer has to decide whether to finance the deal using stock or pay cash. Second, if the acquirer decides to issue stock, it then must decide whether to offer a fixed value of shares or a fixed number of them. Offering cash places all the potential risks and rewards with the acquirer--and sends a strong signal to the markets that it has confidence in the value not only of the deal but in its own stock. By issuing shares, however, an acquirer in essence offers to share the newly merged company with the stockholders of the acquired company--a signal the market often interprets as a lack of confidence in the value of the acquirer's stock. Offering a fixed number of shares reinforces that impression because it requires the selling stockholders to share the risk that the value of the acquirer's stock will decline before the deal goes through. Offering a fixed value of shares sends a more confident signal to the markets, as the acquirer assumes all of that risk. The choice between cash and stock should never be made without full and careful consideration of the potential consequences. The all-too-frequent disappointing returns from stock transactions underscore how important the method of payment truly is.

  5. Same description, different values. How service users and providers define patient and public involvement in health care.

    PubMed

    Rise, Marit By; Solbjør, Marit; Lara, Mariela C; Westerlund, Heidi; Grimstad, Hilde; Steinsbekk, Aslak

    2013-09-01

    Patient and public involvement in health care is important, but the existing definitions of the concept do not integrate the stakeholders' own perceptions. To investigate and compare service users' and service providers' own definitions of patient and public involvement and their implications. Qualitative study with mainly individual in-depth semi-structured interviews conducted between June 2007 and June 2009. Data were analysed using a grounded theory approach. A total of 20 patients, 13 public representatives and 44 health service providers/managers in both somatic and mental health care were interviewed. A common definition of patient and public involvement emerged: It is founded on mutual respect, carried out through dialogue aiming at achieving shared decision making. Nevertheless, users and providers assigned different values to the core aspects: Respect was imperative for service users and implied for providers, dialogue was a way to gain respect for service users and to achieve good outcome for providers, and both worried that the other party wanted to make sole decisions. Users and providers need to consider that although they have a common definition of involvement in health care, they assign different values to its aspects. Increasing and improving patient and public involvement therefore requires knowledge on and dialogue between the parties about these differences. © 2011 John Wiley & Sons Ltd.

  6. Response of selected binomial coefficients to varying degrees of matrix sparseness and to matrices with known data interrelationships

    USGS Publications Warehouse

    Archer, A.W.; Maples, C.G.

    1989-01-01

    Numerous departures from ideal relationships are revealed by Monte Carlo simulations of widely accepted binomial coefficients. For example, simulations incorporating varying levels of matrix sparseness (presence of zeros indicating lack of data) and computation of expected values reveal that not only are all common coefficients influenced by zero data, but also that some coefficients do not discriminate between sparse or dense matrices (few zero data). Such coefficients computationally merge mutually shared and mutually absent information and do not exploit all the information incorporated within the standard 2 ?? 2 contingency table; therefore, the commonly used formulae for such coefficients are more complicated than the actual range of values produced. Other coefficients do differentiate between mutual presences and absences; however, a number of these coefficients do not demonstrate a linear relationship to matrix sparseness. Finally, simulations using nonrandom matrices with known degrees of row-by-row similarities signify that several coefficients either do not display a reasonable range of values or are nonlinear with respect to known relationships within the data. Analyses with nonrandom matrices yield clues as to the utility of certain coefficients for specific applications. For example, coefficients such as Jaccard, Dice, and Baroni-Urbani and Buser are useful if correction of sparseness is desired, whereas the Russell-Rao coefficient is useful when sparseness correction is not desired. ?? 1989 International Association for Mathematical Geology.

  7. From micro-correlations to macro-correlations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eliazar, Iddo, E-mail: iddo.eliazar@intel.com

    2016-11-15

    Random vectors with a symmetric correlation structure share a common value of pair-wise correlation between their different components. The symmetric correlation structure appears in a multitude of settings, e.g. mixture models. In a mixture model the components of the random vector are drawn independently from a general probability distribution that is determined by an underlying parameter, and the parameter itself is randomized. In this paper we study the overall correlation of high-dimensional random vectors with a symmetric correlation structure. Considering such a random vector, and terming its pair-wise correlation “micro-correlation”, we use an asymptotic analysis to derive the random vector’smore » “macro-correlation” : a score that takes values in the unit interval, and that quantifies the random vector’s overall correlation. The method of obtaining macro-correlations from micro-correlations is then applied to a diverse collection of frameworks that demonstrate the method’s wide applicability.« less

  8. The priesthood of bioethics and the return of casuistry.

    PubMed

    Wildes, K W

    1993-02-01

    Several recent attempts to develop models of moral reasoning have attempted to use some form of casuistry as a way to resolve the moral controversies of clinical ethics. One of the best known models of casuistry is that of Jonsen and Toulmin who attempt to transpose a particular model of casuistry, that of Roman Catholic confessional practice, to contemporary moral disputes. This attempt is flawed in that it fails to understand both the history of the model it seeks to transpose and the morally pluralistic context of secular, postmodern society. The practice of casuistry which Jonsen and Toulmin wish to revive is a practice set in the context of a community with a shared set of moral values and structures of moral authority. Without a set of common moral values and rankings, and a moral authority to interpret cases the casuistry of the postmodern age will be pluralistic, that is, there will be many casuistries not just one.

  9. Issues in Health Care of Middle Eastern Patients

    PubMed Central

    Lipson, Juliene G.; Meleis, Afaf I.

    1983-01-01

    Relationships between Middle Eastern patients and Western health care professionals are often troubled by mutual misunderstanding of culturally influenced values and communication styles. Although Middle Easterners vary ethnically, they do share a core of common values and behavior that include the importance of affiliation and family, time and space orientations, interactional style and attitudes toward health and illness. Problems in providing health care involve obtaining adequate information, “demanding behavior” by a patient's family, conflicting beliefs about planning ahead and differing patterns of communicating grave diagnoses or “bad news.” There are guidelines that will provide an understanding of the cultural characteristics of Middle Easterners and, therefore, will improve rather than impede their health care. A personal approach and continuity of care by the same health care professional help to bridge the gap between Middle Eastern cultures and Western medical culture. In addition, periodic use of cultural interpreters helps ameliorate the intensity of some cultural issues. PMID:6364575

  10. Sweet taste liking is associated with impulsive behaviors in humans

    PubMed Central

    Weafer, Jessica; Burkhardt, Anne; de Wit, Harriet

    2014-01-01

    Evidence from both human and animal studies suggests that sensitivity to rewarding stimuli is positively associated with impulsive behaviors, including both impulsive decision making and inhibitory control. The current study examined associations between the hedonic value of a sweet taste and two forms of impulsivity (impulsive choice and impulsive action) in healthy young adults (N = 100). Participants completed a sweet taste test in which they rated their liking of various sweetness concentrations. Subjects also completed measures of impulsive choice (delay discounting), and impulsive action (go/no-go task). Subjects who discounted more steeply (i.e., greater impulsive choice) liked the high sweetness concentration solutions more. By contrast, sweet liking was not related to impulsive action. These findings indicate that impulsive choice may be associated with heightened sensitivity to the hedonic value of a rewarding stimulus, and that these constructs might share common underlying neurobiological mechanisms. PMID:24987343

  11. Moral Education in a Multicultural Context: The Malaysian Primary Curriculum.

    ERIC Educational Resources Information Center

    Banks, Ellen C.

    In Malaysia, the national moral education curriculums are designed to develop the values that Malaysians of diverse cultures share or that the government wishes to develop as shared values to bring about religious and ethnic harmony. Moral education for Muslims is incorporated into in-school religious education, while a separate, essentially…

  12. Something Old, Something New: MBA Program Evaluation Using Shift-Share Analysis and Google Trends

    ERIC Educational Resources Information Center

    Davis, Sarah M.; Rodriguez, A. E.

    2014-01-01

    Shift-share analysis is a decomposition technique that is commonly used to measure attributes of regional change. In this method, regional change is decomposed into its relevant functional and competitive parts. This paper introduces traditional shift-share method and its extensions with examples of its applicability and usefulness for program…

  13. A Case for Data Commons

    PubMed Central

    Grossman, Robert L.; Heath, Allison; Murphy, Mark; Patterson, Maria; Wells, Walt

    2017-01-01

    Data commons collocate data, storage, and computing infrastructure with core services and commonly used tools and applications for managing, analyzing, and sharing data to create an interoperable resource for the research community. An architecture for data commons is described, as well as some lessons learned from operating several large-scale data commons. PMID:29033693

  14. Data Rights and Responsibilities

    PubMed Central

    Wyndham, Jessica M.

    2015-01-01

    A human-rights-based analysis can be a useful tool for the scientific community and policy makers as they develop codes of conduct, harmonized standards, and national policies for data sharing. The human rights framework provides a shared set of values and norms across borders, defines rights and responsibilities of various actors involved in data sharing, addresses the potential harms as well as the benefits of data sharing, and offers a framework for balancing competing values. The right to enjoy the benefits of scientific progress and its applications offers a particularly helpful lens through which to view data as both a tool of scientific inquiry to which access is vital and as a product of science from which everyone should benefit. PMID:26297755

  15. What Are Some Common Complications During Labor and Delivery?

    MedlinePlus

    ... complications? Share Facebook Twitter Pinterest Email Print What are some common complications during labor and delivery? Each ... as necessary. Some of the more common complications are: 1 , 2 Labor that does not progress. Sometimes ...

  16. Membership Eligibility and Performance Measures for PESP

    EPA Pesticide Factsheets

    PESP members represent diverse segments of the pesticide-user community. They often share common pesticide challenges. PESP membership is divided into four groups of members who share pesticide interests, e.g., community IPM and sustainable agriculture.

  17. Study of parameters of the nearest neighbour shared algorithm on clustering documents

    NASA Astrophysics Data System (ADS)

    Mustika Rukmi, Alvida; Budi Utomo, Daryono; Imro’atus Sholikhah, Neni

    2018-03-01

    Document clustering is one way of automatically managing documents, extracting of document topics and fastly filtering information. Preprocess of clustering documents processed by textmining consists of: keyword extraction using Rapid Automatic Keyphrase Extraction (RAKE) and making the document as concept vector using Latent Semantic Analysis (LSA). Furthermore, the clustering process is done so that the documents with the similarity of the topic are in the same cluster, based on the preprocesing by textmining performed. Shared Nearest Neighbour (SNN) algorithm is a clustering method based on the number of "nearest neighbors" shared. The parameters in the SNN Algorithm consist of: k nearest neighbor documents, ɛ shared nearest neighbor documents and MinT minimum number of similar documents, which can form a cluster. Characteristics The SNN algorithm is based on shared ‘neighbor’ properties. Each cluster is formed by keywords that are shared by the documents. SNN algorithm allows a cluster can be built more than one keyword, if the value of the frequency of appearing keywords in document is also high. Determination of parameter values on SNN algorithm affects document clustering results. The higher parameter value k, will increase the number of neighbor documents from each document, cause similarity of neighboring documents are lower. The accuracy of each cluster is also low. The higher parameter value ε, caused each document catch only neighbor documents that have a high similarity to build a cluster. It also causes more unclassified documents (noise). The higher the MinT parameter value cause the number of clusters will decrease, since the number of similar documents can not form clusters if less than MinT. Parameter in the SNN Algorithm determine performance of clustering result and the amount of noise (unclustered documents ). The Silhouette coeffisient shows almost the same result in many experiments, above 0.9, which means that SNN algorithm works well with different parameter values.

  18. Interface cloning and sharing: Interaction designs for conserving labor and maintaining state across 24X7 sensor operations teams

    NASA Astrophysics Data System (ADS)

    Ganter, John H.; Reeves, Paul C.

    2017-05-01

    Processing remote sensing data is the epitome of computation, yet real-time collection systems remain human-labor intensive. Operator labor is consumed by both overhead tasks (cost) and value-added production (benefit). In effect, labor is taxed and then lost. When an operator comes on-shift, they typically duplicate setup work that their teammates have already performed many times. "Pass down" of state information can be difficult if security restrictions require total logouts and blank screens - hours or even days of valuable history and context are lost. As work proceeds, duplicative effort is common because it is typically easier for operators to "do it over" rather than share what others have already done. As we begin a major new system version, we are refactoring the user interface to reduce time and motion losses. Working with users, we are developing "click budgets" to streamline interface use. One basic function is shared clipboards to reduce the use of sticky notes and verbal communication of data strings. We illustrate two additional designs to share work: window copying and window sharing. Copying (technically, shallow or deep object cloning) allows any system user to duplicate a window and configuration for themselves or another to use. Sharing allows a window to have multiple users: shareholders with read-write functionality and viewers with read-only. These solutions would allow windows to persist across multiple shifts, with a rotating cast of shareholders and viewers. Windows thus become durable objects of shared effort and persistent state. While these are low-tech functions, the cumulative labor savings in a 24X7 crew position (525,000 minutes/year spread over multiple individuals) would be significant. New design and implementation is never free and these investments typically do not appeal to government acquisition officers with short-term acquisition-cost concerns rather than a long-term O and M (operations and maintenance) perspective. We share some successes in educating some officers, in collaboration with system users, about the human capital involved in operating the systems they are acquiring.

  19. Anti-angiogenic property of edible berries.

    PubMed

    Roy, Sashwati; Khanna, Savita; Alessio, Helaine M; Vider, Jelena; Bagchi, Debasis; Bagchi, Manashi; Sen, Chandan K

    2002-09-01

    Recent studies show that edible berries may have potent chemopreventive properties. Anti-angiogenic approaches to prevent and treat cancer represent a priority area in investigative tumor biology. Vascular endothelial growth factor (VEGF) plays a crucial role for the vascularization of tumors. The vasculature in adult skin remains normally quiescent. However, skin retains the capacity for brisk initiation of angiogenesis during inflammatory skin diseases such as psoriasis and skin cancers. We sought to test the effects of multiple berry extracts on inducible VEGF expression by human HaCaT keratinocytes. Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seed, and strawberry) and a grape seed proanthocyanidin extract (GSPE) were studied. The extracts and uptake of their constituents by HaCaT were studied using a multi-channel HPLC-CoulArray approach. Antioxidant activity of the extracts was determined by ORAC. Cranberry, elderberry and raspberry seed samples were observed to possess comparable ORAC values. The antioxidant capacity of these samples was significantly lower than that of the other samples studied. The ORAC values of strawberry powder and GSPE were higher than cranberry, elderberry or raspberry seed but significantly lower than the other samples studied. Wild bilberry and blueberry extracts possessed the highest ORAC values. Each of the berry samples studied significantly inhibited both H2O2 as well as TNF alpha induced VEGF expression by the human keratinocytes. This effect was not shared by other antioxidants such as alpha-tocopherol or GSPE but was commonly shared by pure flavonoids. Matrigel assay using human dermal microvascular endothelial cells showed that edible berries impair angiogenesis.

  20. Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins.

    PubMed

    Guerrero-Muñoz, Marcos J; Castillo-Carranza, Diana L; Kayed, Rakez

    2014-04-15

    Impaired proteostasis is one of the main features of all amyloid diseases, which are associated with the formation of insoluble aggregates from amyloidogenic proteins. The aggregation process can be caused by overproduction or poor clearance of these proteins. However, numerous reports suggest that amyloid oligomers are the most toxic species, rather than insoluble fibrillar material, in Alzheimer's, Parkinson's, and Prion diseases, among others. Although the exact protein that aggregates varies between amyloid disorders, they all share common structural features that can be used as therapeutic targets. In this review, we focus on therapeutic approaches against shared features of toxic oligomeric structures and future directions. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Comparing spatially explicit ecological and social values for natural areas to identify effective conservation strategies.

    PubMed

    Bryan, Brett Anthony; Raymond, Christopher Mark; Crossman, Neville David; King, Darran

    2011-02-01

    Consideration of the social values people assign to relatively undisturbed native ecosystems is critical for the success of science-based conservation plans. We used an interview process to identify and map social values assigned to 31 ecosystem services provided by natural areas in an agricultural landscape in southern Australia. We then modeled the spatial distribution of 12 components of ecological value commonly used in setting spatial conservation priorities. We used the analytical hierarchy process to weight these components and used multiattribute utility theory to combine them into a single spatial layer of ecological value. Social values assigned to natural areas were negatively correlated with ecological values overall, but were positively correlated with some components of ecological value. In terms of the spatial distribution of values, people valued protected areas, whereas those natural areas underrepresented in the reserve system were of higher ecological value. The habitats of threatened animal species were assigned both high ecological value and high social value. Only small areas were assigned both high ecological value and high social value in the study area, whereas large areas of high ecological value were of low social value, and vice versa. We used the assigned ecological and social values to identify different conservation strategies (e.g., information sharing, community engagement, incentive payments) that may be effective for specific areas. We suggest that consideration of both ecological and social values in selection of conservation strategies can enhance the success of science-based conservation planning. ©2010 Society for Conservation Biology.

  2. Canonical Commonality Analysis.

    ERIC Educational Resources Information Center

    Leister, K. Dawn

    Commonality analysis is a method of partitioning variance that has advantages over more traditional "OVA" methods. Commonality analysis indicates the amount of explanatory power that is "unique" to a given predictor variable and the amount of explanatory power that is "common" to or shared with at least one predictor…

  3. 42 CFR 447.45 - Timely claims payment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... common physical location; (2) The practitioners share common waiting areas, examining rooms, treatment... common physical location other than the direct furnishing of professional health care services by the... the use of the common physical location or related support services, on a basis related to amounts...

  4. An Underlying Common Factor, Influenced by Genetics and Unique Environment, Explains the Covariation Between Major Depressive Disorder, Generalized Anxiety Disorder, and Burnout: A Swedish Twin Study.

    PubMed

    Mather, Lisa; Blom, Victoria; Bergström, Gunnar; Svedberg, Pia

    2016-12-01

    Depression and anxiety are highly comorbid due to shared genetic risk factors, but less is known about whether burnout shares these risk factors. We aimed to examine whether the covariation between major depressive disorder (MDD), generalized anxiety disorder (GAD), and burnout is explained by common genetic and/or environmental factors. This cross-sectional study included 25,378 Swedish twins responding to a survey in 2005-2006. Structural equation models were used to analyze whether the trait variances and covariances were due to additive genetics, non-additive genetics, shared environment, and unique environment. Univariate analyses tested sex limitation models and multivariate analysis tested Cholesky, independent pathway, and common pathway models. The phenotypic correlations were 0.71 (0.69-0.74) between MDD and GAD, 0.58 (0.56-0.60) between MDD and burnout, and 0.53 (0.50-0.56) between GAD and burnout. Heritabilities were 45% for MDD, 49% for GAD, and 38% for burnout; no statistically significant sex differences were found. A common pathway model was chosen as the final model. The common factor was influenced by genetics (58%) and unique environment (42%), and explained 77% of the variation in MDD, 69% in GAD, and 44% in burnout. GAD and burnout had additive genetic factors unique to the phenotypes (11% each), while MDD did not. Unique environment explained 23% of the variability in MDD, 20% in GAD, and 45% in burnout. In conclusion, the covariation was explained by an underlying common factor, largely influenced by genetics. Burnout was to a large degree influenced by unique environmental factors not shared with MDD and GAD.

  5. Deciding together? Best interests and shared decision-making in paediatric intensive care.

    PubMed

    Birchley, Giles

    2014-09-01

    In the western healthcare, shared decision making has become the orthodox approach to making healthcare choices as a way of promoting patient autonomy. Despite the fact that the autonomy paradigm is poorly suited to paediatric decision making, such an approach is enshrined in English common law. When reaching moral decisions, for instance when it is unclear whether treatment or non-treatment will serve a child's best interests, shared decision making is particularly questionable because agreement does not ensure moral validity. With reference to current common law and focusing on intensive care practice, this paper investigates what claims shared decision making may have to legitimacy in a paediatric intensive care setting. Drawing on key texts, I suggest these identify advantages to parents and clinicians but not to the child who is the subject of the decision. Without evidence that shared decision making increases the quality of the decision that is being made, it appears that a focus on the shared nature of a decision does not cohere with the principle that the best interests of the child should remain paramount. In the face of significant pressures toward the displacement of the child's interests in a shared decision, advantages of a shared decision to decisional quality require elucidation. Although a number of arguments of this nature may have potential, should no such advantages be demonstrable we have cause to revise our commitment to either shared decision making or the paramountcy of the child in these circumstances.

  6. The Materials Commons: A Collaboration Platform and Information Repository for the Global Materials Community

    NASA Astrophysics Data System (ADS)

    Puchala, Brian; Tarcea, Glenn; Marquis, Emmanuelle. A.; Hedstrom, Margaret; Jagadish, H. V.; Allison, John E.

    2016-08-01

    Accelerating the pace of materials discovery and development requires new approaches and means of collaborating and sharing information. To address this need, we are developing the Materials Commons, a collaboration platform and information repository for use by the structural materials community. The Materials Commons has been designed to be a continuous, seamless part of the scientific workflow process. Researchers upload the results of experiments and computations as they are performed, automatically where possible, along with the provenance information describing the experimental and computational processes. The Materials Commons website provides an easy-to-use interface for uploading and downloading data and data provenance, as well as for searching and sharing data. This paper provides an overview of the Materials Commons. Concepts are also outlined for integrating the Materials Commons with the broader Materials Information Infrastructure that is evolving to support the Materials Genome Initiative.

  7. Exploring the Role of Value Networks for Software Innovation

    NASA Astrophysics Data System (ADS)

    Morgan, Lorraine; Conboy, Kieran

    This paper describes a research-in-progress that aims to explore the applicability and implications of open innovation practices in two firms - one that employs agile development methods and another that utilizes open source software. The open innovation paradigm has a lot in common with open source and agile development methodologies. A particular strength of agile approaches is that they move away from 'introverted' development, involving only the development personnel, and intimately involves the customer in all areas of software creation, supposedly leading to the development of a more innovative and hence more valuable information system. Open source software (OSS) development also shares two key elements of the open innovation model, namely the collaborative development of the technology and shared rights to the use of the technology. However, one shortfall with agile development in particular is the narrow focus on a single customer representative. In response to this, we argue that current thinking regarding innovation needs to be extended to include multiple stakeholders both across and outside the organization. Additionally, for firms utilizing open source, it has been found that their position in a network of potential complementors determines the amount of superior value they create for their customers. Thus, this paper aims to get a better understanding of the applicability and implications of open innovation practices in firms that employ open source and agile development methodologies. In particular, a conceptual framework is derived for further testing.

  8. Supporting Common Ground Development in the Operation Room through Information Display Systems

    PubMed Central

    Feng, Yuanyuan; Mentis, Helena M.

    2016-01-01

    Effective information sharing is crucial for clinical team coordination. Most information display systems have been designed to replace verbal communication. However, information may not be available for capture before a communication event and information needs often become clear and evident through an evolving discourse. Thus, to build tools to support clinical team in situ information sharing, we need a better understanding of how evolving information needs are identified and satisfied. In this study, we used sequential analysis techniques to explore the ways communication and information sharing events between an attending surgeon and a resident change throughout a laparoscopic surgery. We demonstrate how common ground is developed and maintained, and how information needs change through the efforts of grounding. From our findings, we suggest that the design for information display systems could encourage communication and support the articulation work that is necessary to accomplish the information sharing. PMID:28269936

  9. Supporting Common Ground Development in the Operation Room through Information Display Systems.

    PubMed

    Feng, Yuanyuan; Mentis, Helena M

    2016-01-01

    Effective information sharing is crucial for clinical team coordination. Most information display systems have been designed to replace verbal communication. However, information may not be available for capture before a communication event and information needs often become clear and evident through an evolving discourse. Thus, to build tools to support clinical team in situ information sharing, we need a better understanding of how evolving information needs are identified and satisfied. In this study, we used sequential analysis techniques to explore the ways communication and information sharing events between an attending surgeon and a resident change throughout a laparoscopic surgery. We demonstrate how common ground is developed and maintained, and how information needs change through the efforts of grounding. From our findings, we suggest that the design for information display systems could encourage communication and support the articulation work that is necessary to accomplish the information sharing.

  10. Shared Values and Socio-Cultural Norms: E-Learning Technologies from a Social Practice Perspective

    ERIC Educational Resources Information Center

    Shih, Patti; Velan, Gary M.; Shulruf, Boaz

    2017-01-01

    From a perspective of social practice, learning is a socially constituted practice that is imbued with socio-culturally significant meanings and shaped by the values and norms shared within a community of learners. This focus group study examines the role of e-learning technologies in mediating the social practice of learning among coursework…

  11. Sticking with Your University: The Importance of Satisfaction, Trust, Image, and Shared Values

    ERIC Educational Resources Information Center

    Schlesinger, Walesska; Cervera, Amparo; Pérez-Cabañero, Carmen

    2017-01-01

    In a context of increasing competition and financial difficulties for higher education institutions, alumni loyalty is a key factor for survival and success. This study tests a model derived from a relationship marketing perspective to investigate the roles of four variables (brand image, trust, satisfaction, and shared values) in the direct and…

  12. 77 FR 36599 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... Change Relating to the Accuvest Global Long Short ETF (Formerly the Mars Hill Global Relative Value ETF...) applicable to, the Accuvest Global Long Short ETF (``Fund'') (formerly known as the Mars Hill Global Relative... the Exchange of shares (``Shares'') of the Mars Hill Global Relative Value ETF, a series of Advisor...

  13. The Role of Reachers' Shared Values and Objectives in Promoting Intercultural and Inclusive School Cultures: A Case Study

    ERIC Educational Resources Information Center

    Miravet, Lidon Moliner; García, Odet Moliner

    2013-01-01

    This article presents an analysis of teachers' impressions of their shared objectives and values, together with their conceptions of interculturality and inclusion. The educational reality of a school in Valencia (Spain) is described, based on the exploration through semi-structured interviews. From the systematically categorized information, we…

  14. Social network modulation of reward-related signals

    PubMed Central

    Fareri, Dominic S.; Niznikiewicz, Michael A.; Lee, Victoria K.; Delgado, Mauricio R.

    2012-01-01

    Everyday goals and experiences are often shared with others who may hold different places within our social networks. We investigated whether the experience of sharing a reward differs with respect to social network. Twenty human participants played a card guessing game for shared monetary outcomes with three partners: a computer, a confederate (out-of-network), and a friend (in-network). Participants subjectively rated the experience of sharing a reward more positively with their friend than the other partners. Neuroimaging results support participants’ subjective reports, as ventral striatal BOLD responses were more robust when sharing monetary gains with a friend, as compared to with the confederate or computer, suggesting a higher value for sharing with an in-network partner. Interestingly, ratings of social closeness co-varied with this activity, resulting in a significant partner × closeness interaction: exploratory analysis showed that only participants reporting higher levels of closeness demonstrated partner-related differences in striatal BOLD response. These results suggest that reward valuation in social contexts is sensitive to distinctions of social network, such that sharing positive experiences with in-network others may carry higher value. PMID:22745503

  15. Ethno veterinary uses of medicinal plants of district Karak, Pakistan.

    PubMed

    Khattak, Noor Saeed; Nouroz, Faisal; Inayat Ur Rahman; Noreen, Shumaila

    2015-08-02

    In the study area, the traditional knowledge regarding the uses of local wild medicinal plants for treating diseases of domestic animals and birds is totally in the custody of elders of the existing community. The young ones are not much aware about such important practices. The main aim of the study was to document and to release this knowledge from the custody of elders and share with the community. Total 115 people between 20 and 80 years of age were interviewed and information was collected through semi-structured questionnaires. The data obtained were quantitatively analyzed using the use value (UV) formula. The collected specimens were pressed, dried, preserved, mounted on Herbarium sheets, identified properly and were submitted in the Herbarium, Department of Botany, Hazara University, Mansehra, Pakistan. With the co-ordination and cooperation of the local people, 46 plant species of 42 genera belonging to 31 families were collected, 3 were monocotyledons while 43 plant species belonged to dicotyledonae class. Considering taxonomic characteristics, it was confirmed that 12 trees, 10 shrubs and 22 herbs were commonly used by the local people in ethno veterinary practices. Two plants like Cistanche tubulosa and Cuscuta reflexa from family Orobanchaceae and family Cuscutaceae respectively lack chlorophyll and are parasites on host plants like Doedonia, Ziziphus, Calligonum and Calotropis. The powder of both plants showed great ethno veterinary value. The parts of 46 plant species commonly used for ethno veterinary practices were whole plants (32.60%), leaves (26.08%), fruits (17.39%), stems (13.04%) and roots (10.86%). Medicinal plants were administered through various routes i.e. oral (78.26%), skin (17.21%) and smoke (4.34%). The traditional knowledge of local plants of ethno veterinary values is mainly possessed by elders and transmitted from generation to generation with chances of elimination of such traditional knowledge due to less awareness. The present study was designed to document this ethno veterinary related knowledge and to share it with community members for use in future. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  16. 48 CFR 48.104-3 - Sharing collateral savings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Sharing collateral savings. 48.104-3 Section 48.104-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT VALUE ENGINEERING Policies and Procedures 48.104-3 Sharing collateral savings. (a) The...

  17. Resolving the Problem of Aligning Communities of Interest, Data Format Differences, Orthogonal Sensor Views, Intermittency, and Security - DoD Homeland Security Command and Control Advanced Concept Technology Demonstration

    DTIC Science & Technology

    2005-06-01

    provisioning, maintaining and guaranteeing service levels for the shared services ? Although these shared, distributed services lie well within the... shared services that interact with a common object definition for transporting alerts. The system is built on top of a rapid SOA application

  18. Innovation and Cultural Change Task Group Report

    DTIC Science & Technology

    2006-05-01

    authoritative information sources…common analytic methods… Chief Administrative Officer and Shared Services Problem • Core functions are not well...in a crippling fashion Solution • Chief administrative officer • Shared services (market principles, not primarily consolidation) QDR • Under...Additional Governance Reforms” DoD is said to be considering: – Migrating toward a shared services model for support functions… Defense Business Board

  19. 12 CFR 225.143 - Policy statement on nonvoting equity investments by bank holding companies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... investor, and revert to voting shares when transferred to a third party. (e) Review by the Board. This... acquisition of preferred stock or nonvoting common shares of the acquiree. Because of the evident interest in... more than 5 per cent of the voting shares of a bank without the Board's prior approval. (12 U.S.C. 1842...

  20. "It's Mine!" Does Sharing with Siblings at Age 3 Predict Sharing with Siblings, Friends, and Unfamiliar Peers at Age 6?

    ERIC Educational Resources Information Center

    White, Naomi; Ensor, Rosie; Marks, Alex; Jacobs, Lorna; Hughes, Claire

    2014-01-01

    Research Findings: Studies of children's prosocial behavior typically focus on prosocial acts with a specific partner (e.g., a friend, peer, or sibling), and comparisons of prosociality in different contexts are rare. To address this gap, the current study examined predictive links among children's spontaneous sharing (a common and important form…

  1. A comparative analysis of moral principles and behavioral norms in eight ethical codes relevant to health sciences librarianship, medical informatics, and the health professions.

    PubMed

    Byrd, Gary D; Winkelstein, Peter

    2014-10-01

    Based on the authors' shared interest in the interprofessional challenges surrounding health information management, this study explores the degree to which librarians, informatics professionals, and core health professionals in medicine, nursing, and public health share common ethical behavior norms grounded in moral principles. Using the "Principlism" framework from a widely cited textbook of biomedical ethics, the authors analyze the statements in the ethical codes for associations of librarians (Medical Library Association [MLA], American Library Association, and Special Libraries Association), informatics professionals (American Medical Informatics Association [AMIA] and American Health Information Management Association), and core health professionals (American Medical Association, American Nurses Association, and American Public Health Association). This analysis focuses on whether and how the statements in these eight codes specify core moral norms (Autonomy, Beneficence, Non-Maleficence, and Justice), core behavioral norms (Veracity, Privacy, Confidentiality, and Fidelity), and other norms that are empirically derived from the code statements. These eight ethical codes share a large number of common behavioral norms based most frequently on the principle of Beneficence, then on Autonomy and Justice, but rarely on Non-Maleficence. The MLA and AMIA codes share the largest number of common behavioral norms, and these two associations also share many norms with the other six associations. The shared core of behavioral norms among these professions, all grounded in core moral principles, point to many opportunities for building effective interprofessional communication and collaboration regarding the development, management, and use of health information resources and technologies.

  2. Shared molecular networks in orofacial and neural tube development.

    PubMed

    Kousa, Youssef A; Mansour, Tamer A; Seada, Haitham; Matoo, Samaneh; Schutte, Brian C

    2017-01-30

    Single genetic variants can affect multiple tissues during development. Thus it is possible that disruption of shared gene regulatory networks might underlie syndromic presentations. In this study, we explore this idea through examination of two critical developmental programs that control orofacial and neural tube development and identify shared regulatory factors and networks. Identification of these networks has the potential to yield additional candidate genes for poorly understood developmental disorders and assist in modeling and perhaps managing risk factors to prevent morbidly and mortality. We reviewed the literature to identify genes common between orofacial and neural tube defects and development. We then conducted a bioinformatic analysis to identify shared molecular targets and pathways in the development of these tissues. Finally, we examine publicly available RNA-Seq data to identify which of these genes are expressed in both tissues during development. We identify common regulatory factors in orofacial and neural tube development. Pathway enrichment analysis shows that folate, cancer and hedgehog signaling pathways are shared in neural tube and orofacial development. Developing neural tissues differentially express mouse exencephaly and cleft palate genes, whereas developing orofacial tissues were enriched for both clefting and neural tube defect genes. These data suggest that key developmental factors and pathways are shared between orofacial and neural tube defects. We conclude that it might be most beneficial to focus on common regulatory factors and pathways to better understand pathology and develop preventative measures for these birth defects. Birth Defects Research 109:169-179, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. A comparative analysis of moral principles and behavioral norms in eight ethical codes relevant to health sciences librarianship, medical informatics, and the health professions

    PubMed Central

    Byrd, Gary D.; Winkelstein, Peter

    2014-01-01

    Objective: Based on the authors' shared interest in the interprofessional challenges surrounding health information management, this study explores the degree to which librarians, informatics professionals, and core health professionals in medicine, nursing, and public health share common ethical behavior norms grounded in moral principles. Methods: Using the “Principlism” framework from a widely cited textbook of biomedical ethics, the authors analyze the statements in the ethical codes for associations of librarians (Medical Library Association [MLA], American Library Association, and Special Libraries Association), informatics professionals (American Medical Informatics Association [AMIA] and American Health Information Management Association), and core health professionals (American Medical Association, American Nurses Association, and American Public Health Association). This analysis focuses on whether and how the statements in these eight codes specify core moral norms (Autonomy, Beneficence, Non-Maleficence, and Justice), core behavioral norms (Veracity, Privacy, Confidentiality, and Fidelity), and other norms that are empirically derived from the code statements. Results: These eight ethical codes share a large number of common behavioral norms based most frequently on the principle of Beneficence, then on Autonomy and Justice, but rarely on Non-Maleficence. The MLA and AMIA codes share the largest number of common behavioral norms, and these two associations also share many norms with the other six associations. Implications: The shared core of behavioral norms among these professions, all grounded in core moral principles, point to many opportunities for building effective interprofessional communication and collaboration regarding the development, management, and use of health information resources and technologies. PMID:25349543

  4. Utility Green-Pricing Programs: What Defines Success? (Topical Issues Brief)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swezey, B.; Bird, L.

    2001-09-13

    ''Green pricing'' is an optional service through which customers can support a greater level of investment by their electric utility in renewable energy technologies. Electric utilities in 29 states are now implementing green-pricing programs. This report examines important elements of green-pricing programs, including the different types of programs offered, the premiums charged, customer response, and additional factors that experience indicates are key to the development of successful programs. The best-performing programs tend to share a number of common attributes related to product design, value creation, product pricing, and program implementation. The report ends with a list of ''best practices'' formore » utilities to follow when developing and implementing programs.« less

  5. Linguistic measures of chemical diversity and the "keywords" of molecular collections.

    PubMed

    Woźniak, Michał; Wołos, Agnieszka; Modrzyk, Urszula; Górski, Rafał L; Winkowski, Jan; Bajczyk, Michał; Szymkuć, Sara; Grzybowski, Bartosz A; Eder, Maciej

    2018-05-15

    Computerized linguistic analyses have proven of immense value in comparing and searching through large text collections ("corpora"), including those deposited on the Internet - indeed, it would nowadays be hard to imagine browsing the Web without, for instance, search algorithms extracting most appropriate keywords from documents. This paper describes how such corpus-linguistic concepts can be extended to chemistry based on characteristic "chemical words" that span more than traditional functional groups and, instead, look at common structural fragments molecules share. Using these words, it is possible to quantify the diversity of chemical collections/databases in new ways and to define molecular "keywords" by which such collections are best characterized and annotated.

  6. Leadership: social identity and guiding from within.

    PubMed

    Kerfoot, Karlene M

    2009-01-01

    An important field in leadership research is that of the social identity of the group and what that means for leadership. In health care, there are many different types of social identities that vary by hospital, geography, and profession. Leaders often sabotage their effectiveness when they do not consider the social values of the group. The work of leaders is to help move units and organizations to a higher level of performance. Identifying the social identity of the group is the first step. The most successful have expertise in assessing the social identity of groups and developing a commonality of a shared vision that represents the best work of the group and of the leader.

  7. Leadership: social identity and guiding from within.

    PubMed

    Kerfoot, Karlene M

    2007-01-01

    An important field in leadership research is that of the social identity of the group and what that means for leadership. In health care, there are many different types of social identities that vary by hospital, geography, and profession. Leaders often sabotage their effectiveness when they do not consider the social values of the group. The work of leaders is to help move units and organizations to a higher level of performance. Identifying the social identity of the group is the first step. The most successful have expertise in assessing the social identity of groups and developing a commonality of a shared vision that represents the best work of the group and of the leader.

  8. Value of Vintage Observatories and Historic Telescopes in Communicating Astronomy with the Public

    NASA Astrophysics Data System (ADS)

    Bell, T. E.

    2010-10-01

    The Antique Telescope Society convened a thematic workshop, The Vintage Observatory: Thriving in the 21st Century, on 2-4 May 2008. The workshop's purpose was to bring together those charged with the care of observatories and telescopes built before World War II, to examine common issues and share practical solutions, specifically in preparation for the International Year of Astronomy in 2009. Although much of the workshop concerned issues of preservation and restoration, several sessions focused on the uses of historical artefacts as a means for public education and outreach on astronomy and the history of astronomy, including discussion of the unique opportunities vintage observatories and telescopes offer in intriguing the public about astronomy.

  9. Data governance and data sharing agreements for community-wide health information exchange: lessons from the beacon communities.

    PubMed

    Allen, Claudia; Des Jardins, Terrisca R; Heider, Arvela; Lyman, Kristin A; McWilliams, Lee; Rein, Alison L; Schachter, Abigail A; Singh, Ranjit; Sorondo, Barbara; Topper, Joan; Turske, Scott A

    2014-01-01

    Unprecedented efforts are underway across the United States to electronically capture and exchange health information to improve health care and population health, and reduce costs. This increased collection and sharing of electronic patient data raises several governance issues, including privacy, security, liability, and market competition. Those engaged in such efforts have had to develop data sharing agreements (DSAs) among entities involved in information exchange, many of whom are "nontraditional" health care entities and/or new partners. This paper shares lessons learned based on the experiences of six federally funded communities participating in the Beacon Community Cooperative Agreement Program, and offers guidance for navigating data governance issues and developing DSAs to facilitate community-wide health information exchange. While all entities involved in electronic data sharing must address governance issues and create DSAs accordingly, until recently little formal guidance existed for doing so - particularly for community-based initiatives. Despite this lack of guidance, together the Beacon Communities' experiences highlight promising strategies for navigating complex governance issues, which may be useful to other entities or communities initiating information exchange efforts to support delivery system transformation. For the past three years, AcademyHealth has provided technical assistance to most of the 17 Beacon Communities, 6 of whom contributed to this collaborative writing effort. Though these communities varied widely in terms of their demographics, resources, and Beacon-driven priorities, common themes emerged as they described their approaches to data governance and DSA development. The 6 Beacon Communities confirmed that DSAs are necessary to satisfy legal and market-based concerns, and they identified several specific issues, many of which have been noted by others involved in network data sharing initiatives. More importantly, these communities identified several promising approaches to timely and effective DSA development, including: stakeholder engagement; identification and effective communication of value; adoption of a parsimonious approach; attention to market-based concerns; flexibility in adapting and expanding existing agreements and partnerships; and anticipation of required time and investment.

  10. Revealing common disease mechanisms shared by tumors of different tissues of origin through semantic representation of genomic alterations and topic modeling.

    PubMed

    Chen, Vicky; Paisley, John; Lu, Xinghua

    2017-03-14

    Cancer is a complex disease driven by somatic genomic alterations (SGAs) that perturb signaling pathways and consequently cellular function. Identifying patterns of pathway perturbations would provide insights into common disease mechanisms shared among tumors, which is important for guiding treatment and predicting outcome. However, identifying perturbed pathways is challenging, because different tumors can have the same perturbed pathways that are perturbed by different SGAs. Here, we designed novel semantic representations that capture the functional similarity of distinct SGAs perturbing a common pathway in different tumors. Combining this representation with topic modeling would allow us to identify patterns in altered signaling pathways. We represented each gene with a vector of words describing its function, and we represented the SGAs of a tumor as a text document by pooling the words representing individual SGAs. We applied the nested hierarchical Dirichlet process (nHDP) model to a collection of tumors of 5 cancer types from TCGA. We identified topics (consisting of co-occurring words) representing the common functional themes of different SGAs. Tumors were clustered based on their topic associations, such that each cluster consists of tumors sharing common functional themes. The resulting clusters contained mixtures of cancer types, which indicates that different cancer types can share disease mechanisms. Survival analysis based on the clusters revealed significant differences in survival among the tumors of the same cancer type that were assigned to different clusters. The results indicate that applying topic modeling to semantic representations of tumors identifies patterns in the combinations of altered functional pathways in cancer.

  11. Female Pattern Hair Loss

    MedlinePlus

    ... Category: Share: Yes No, Keep Private Female Pattern Hair Loss Share | The most common type of hair loss seen in women is androgenetic alopecia, also ... men, it does not have to be complete hair loss. This is seen as hair thinning predominantly ...

  12. Probability distribution of extreme share returns in Malaysia

    NASA Astrophysics Data System (ADS)

    Zin, Wan Zawiah Wan; Safari, Muhammad Aslam Mohd; Jaaman, Saiful Hafizah; Yie, Wendy Ling Shin

    2014-09-01

    The objective of this study is to investigate the suitable probability distribution to model the extreme share returns in Malaysia. To achieve this, weekly and monthly maximum daily share returns are derived from share prices data obtained from Bursa Malaysia over the period of 2000 to 2012. The study starts with summary statistics of the data which will provide a clue on the likely candidates for the best fitting distribution. Next, the suitability of six extreme value distributions, namely the Gumbel, Generalized Extreme Value (GEV), Generalized Logistic (GLO) and Generalized Pareto (GPA), the Lognormal (GNO) and the Pearson (PE3) distributions are evaluated. The method of L-moments is used in parameter estimation. Based on several goodness of fit tests and L-moment diagram test, the Generalized Pareto distribution and the Pearson distribution are found to be the best fitted distribution to represent the weekly and monthly maximum share returns in Malaysia stock market during the studied period, respectively.

  13. 48 CFR 2448.104-3 - Sharing collateral savings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Sharing collateral savings. 2448.104-3 Section 2448.104-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONTRACT MANAGEMENT VALUE ENGINEERING 2448.104-3 Sharing collateral savings. (a) The authority of...

  14. 48 CFR 2448.104-3 - Sharing collateral savings.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Sharing collateral savings. 2448.104-3 Section 2448.104-3 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CONTRACT MANAGEMENT VALUE ENGINEERING 2448.104-3 Sharing collateral savings. (a) The authority of...

  15. 13 CFR 314.5 - Federal Share.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... If the Property is disposed of when its current fair market is $250, the Federal Share is $125 (i.e... Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE PROPERTY General... fair market value of any Property attributable to EDA's participation in the Project. The Federal Share...

  16. Derivation of the extrinsic values of biological diversity from its intrinsic value and of both from the first principles of evolution.

    PubMed

    White, Peter S

    2013-12-01

    Conservation ethics have been based on 2 philosophical value systems: extrinsic value (defined broadly to include all values that derive from something external to the thing valued) and intrinsic value. Valuing biological diversity on the basis of an extrinsic value system is problematic because measurement is often difficult; extrinsic value changes as spatial or temporal scales change; extrinsic value differs on the basis of external factors; some species have trivial or negative extrinsic values; and extrinsic value varies across human cultures and societies and with such factors as socioeconomic conditions, individual experiences, and educational backgrounds. Valuing biological diversity on the basis of an intrinsic value system also poses challenges because intrinsic value can be seen as a disguised form of human extrinsic value; intrinsic value is initially ambiguous as to which objects or characteristics of biological diversity are to being valued; all aspects of biological diversity (e.g., species and ecosystems) are transitory; species and ecosystems are not static concrete entities; and intrinsic value of one species is often in conflict with the intrinsic value of other species. Extrinsic and intrinsic value systems share a common origin, such that extrinsic values are always derived from intrinsic value and life mutely expresses both intrinsic and extrinsic values-these are derived from and are products of biological evolution. Probing the values that underlie conservation helps the community clearly articulate its aims. Derivación de los Valores Extrínsecos de la Biodiversidad a Partir de sus Valores Intrínsecos y de Ambos a Partir de los Primeros Principios de la Evolución. © 2013 Society for Conservation Biology.

  17. A 3D QSAR study of betulinic acid derivatives as anti-tumor agents using topomer CoMFA: model building studies and experimental verification.

    PubMed

    Ding, Weimin; Sun, Miao; Luo, Shaman; Xu, Tao; Cao, Yibo; Yan, Xiufeng; Wang, Yang

    2013-08-22

    Betulinic acid (BA) is a natural product that exerts its cytotoxicity against various malignant carcinomas without side effects by triggering the mitochondrial pathway to apoptosis. Betulin (BE), the 28-hydroxyl analog of BA, is present in large amounts (up to 30% dry weight) in the outer bark of birch trees, and shares the same pentacyclic triterpenoid core as BA, yet exhibits no significant cytotoxicity. Topomer CoMFA studies were performed on 37 BA and BE derivatives and their in vitro anti-cancer activity results (reported as IC₅₀ values) against HT29 human colon cancer cells in the present study. All derivatives share a common pentacyclic triterpenoid core and the molecules were split into three pieces by cutting at the C-3 and C-28 sites with a consideration toward structural diversity. The analysis gave a leave-one-out cross-validation q² value of 0.722 and a non-cross-validation r² value of 0.974, which suggested that the model has good predictive ability (q² > 0.2). The contour maps illustrated that bulky and electron-donating groups would be favorable for activity at the C-28 site, and a moderately bulky and electron-withdrawing group near the C-3 site would improve this activity. BE derivatives were designed and synthesized according to the modeling result, whereby bulky electronegative groups (maleyl, phthalyl, and hexahydrophthalyl groups) were directly introduced at the C-28 position of BE. The in vitro cytotoxicity values of the given analogs against HT29 cells were consistent with the predicted values, proving that the present topomer CoMFA model is successful and that it could potentially guide the synthesis of new betulinic acid derivatives with high anti-cancer activity. The IC₅₀ values of these three new compounds were also assayed in five other tumor cell lines. 28-O-hexahydrophthalyl BE exhibited the greatest anti-cancer activities and its IC₅₀ values were lower than those of BA in all cell lines, excluding DU145 cells.

  18. Engaging national organizations for knowledge translation: Comparative case studies in knowledge value mapping

    PubMed Central

    2011-01-01

    Background Government sponsors of research and development, along with their funded investigators, are increasingly tasked with demonstrating evidence of knowledge use by nontraditional audiences. This requires efforts to translate their findings for effective communication. For technology-related knowledge, these audiences include clinicians, consumers, manufacturers, public policy agencies, and knowledge brokers. One potentially efficient approach is to communicate research findings through relevant national organizations. However, this requires an understanding of how such organizations view and treat research knowledge, which can be determined through knowledge-value mapping. Do knowledge values differ between national organizations representing different audiences? Can a deeper understanding of knowledge values help sponsors, investigators, and organizations better communicate research findings to stakeholders? Methods A series of comparative case studies on knowledge-value mapping were derived through interviews with spokespersons for six national organizations. The semi-structured interviews followed a 10-item questionnaire to characterize different ways in which each organization engages with research-based knowledge. Each participating organization represents a particular stakeholder group, while all share a common interest in the research subject matter. Results Each national organization considers the value of the research knowledge in the context of their organization's mission and the interests of their members. All are interested in collaborating with researchers to share relevant findings, while they vary along the following dimensions of knowledge engagement: create, identify, translate, adapt, communicate, use, promote, absorptive capacity, and recommendations for facilitation. Conclusions The principles of knowledge translation suggest that investigators can increase use by tailoring the format and context of their findings to the absorptive capacity of nonscholars. Greater absorption should result in higher levels of knowledge awareness, interest, and use, which can then be documented. National organizations and their members, in turn, can strive to optimize their absorptive capacities regarding the state of the sciences. This combination will ensure the highest possible return on public investment in research activities. This knowledge-value mapping study concludes that national organizations are appropriate channels for communicating research findings and for meeting statutory requirements and general expectations for generating and documenting knowledge use. PMID:21910866

  19. Engaging national organizations for knowledge translation: comparative case studies in knowledge value mapping.

    PubMed

    Lane, Joseph P; Rogers, Juan D

    2011-09-12

    Government sponsors of research and development, along with their funded investigators, are increasingly tasked with demonstrating evidence of knowledge use by nontraditional audiences. This requires efforts to translate their findings for effective communication. For technology-related knowledge, these audiences include clinicians, consumers, manufacturers, public policy agencies, and knowledge brokers. One potentially efficient approach is to communicate research findings through relevant national organizations. However, this requires an understanding of how such organizations view and treat research knowledge, which can be determined through knowledge-value mapping. Do knowledge values differ between national organizations representing different audiences? Can a deeper understanding of knowledge values help sponsors, investigators, and organizations better communicate research findings to stakeholders? A series of comparative case studies on knowledge-value mapping were derived through interviews with spokespersons for six national organizations. The semi-structured interviews followed a 10-item questionnaire to characterize different ways in which each organization engages with research-based knowledge. Each participating organization represents a particular stakeholder group, while all share a common interest in the research subject matter. Each national organization considers the value of the research knowledge in the context of their organization's mission and the interests of their members. All are interested in collaborating with researchers to share relevant findings, while they vary along the following dimensions of knowledge engagement: create, identify, translate, adapt, communicate, use, promote, absorptive capacity, and recommendations for facilitation. The principles of knowledge translation suggest that investigators can increase use by tailoring the format and context of their findings to the absorptive capacity of nonscholars. Greater absorption should result in higher levels of knowledge awareness, interest, and use, which can then be documented. National organizations and their members, in turn, can strive to optimize their absorptive capacities regarding the state of the sciences. This combination will ensure the highest possible return on public investment in research activities. This knowledge-value mapping study concludes that national organizations are appropriate channels for communicating research findings and for meeting statutory requirements and general expectations for generating and documenting knowledge use.

  20. [Cancer screening in clinical practice: the value of shared decision-making].

    PubMed

    Cornuz, Jacques; Junod, Noëlle; Pasche, Olivier; Guessous, Idris

    2010-07-14

    Shared decision-making approach to uncertain clinical situations such as cancer screening seems more appropriate than ever. Shared decision making can be defined as an interactive process where physician and patient share all the stages of the decision making process. For patients who wish to be implicated in the management of their health conditions, physicians might express difficulty to do so. Use of patient decision aids appears to improve such process of shared decision making.

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