Tech High: Globalization and the Future of Canadian Education. A Collection of Critical Perspectives on Social, Cultural, and Political Dilemmas.

ERIC Educational Resources Information Center

Moll, Marita, Ed.

If the public policy goal to connect all schools to the information highway becomes a reality, public education as Canadians have known it--a shared social responsibility and a generally shared social experience--could be lost. This volume of contributed papers brings into focus the new context within which the struggle to technologize education…

Towards a global cancer knowledge network: dissecting the current international cancer genomic sequencing landscape.

PubMed

Vis, D J; Lewin, J; Liao, R G; Mao, M; Andre, F; Ward, R L; Calvo, F; Teh, B T; Camargo, A A; Knoppers, B M; Sawyers, C L; Wessels, L F A; Lawler, M; Siu, L L; Voest, E

2017-05-01

While next generation sequencing has enhanced our understanding of the biological basis of malignancy, current knowledge on global practices for sequencing cancer samples is limited. To address this deficiency, we developed a survey to provide a snapshot of current sequencing activities globally, identify barriers to data sharing and use this information to develop sustainable solutions for the cancer research community. A multi-item survey was conducted assessing demographics, clinical data collection, genomic platforms, privacy/ethics concerns, funding sources and data sharing barriers for sequencing initiatives globally. Additionally, respondents were asked as to provide the primary intent of their initiative (clinical diagnostic, research or combination). Of 107 initiatives invited to participate, 59 responded (response rate = 55%). Whole exome sequencing (P = 0.03) and whole genome sequencing (P = 0.01) were utilized less frequently in clinical diagnostic than in research initiatives. Procedures to identify cancer-specific variants were heterogeneous, with bioinformatics pipelines employing different mutation calling/variant annotation algorithms. Measurement of treatment efficacy varied amongst initiatives, with time on treatment (57%) and RECIST (53%) being the most common; however, other parameters were also employed. Whilst 72% of initiatives indicated data sharing, its scope varied, with a number of restrictions in place (e.g. transfer of raw data). The largest perceived barriers to data harmonization were the lack of financial support (P < 0.01) and bioinformatics concerns (e.g. lack of interoperability) (P = 0.02). Capturing clinical data was more likely to be perceived as a barrier to data sharing by larger initiatives than by smaller initiatives (P = 0.01). These results identify the main barriers, as perceived by the cancer sequencing community, to effective sharing of cancer genomic and clinical data. They highlight the need for greater harmonization of technical, ethical and data capture processes in cancer sample sequencing worldwide, in order to support effective and responsible data sharing for the benefit of patients. © The Author 2017. Published by Oxford University Press on behalf of the European Society for Medical Oncology.

The emergence of a global right to health norm--the unresolved case of universal access to quality emergency obstetric care.

PubMed

Hammonds, Rachel; Ooms, Gorik

2014-02-27

The global response to HIV suggests the potential of an emergent global right to health norm, embracing shared global responsibility for health, to assist policy communities in framing the obligations of the domestic state and the international community. Our research explores the extent to which this global right to health norm has influenced the global policy process around maternal health rights, with a focus on universal access to emergency obstetric care. In examining the extent to which arguments stemming from a global right to health norm have been successful in advancing international policy on universal access to emergency obstetric care, we looked at the period from 1985 to 2013 period. We adopted a qualitative case study approach applying a process-tracing methodology using multiple data sources, including an extensive literature review and limited key informant interviews to analyse the international policy agenda setting process surrounding maternal health rights, focusing on emergency obstetric care. We applied John Kingdon's public policy agenda setting streams model to analyse our data. Kingdon's model suggests that to succeed as a mobilising norm, the right to health could work if it can help bring the problem, policy and political streams together, as it did with access to AIDS treatment. Our analysis suggests that despite a normative grounding in the right to health, prioritisation of the specific maternal health entitlements remains fragmented. Despite United Nations recognition of maternal mortality as a human rights issue, the relevant policy communities have not yet managed to shift the policy agenda to prioritise the global right to health norm of shared responsibility for realising access to emergency obstetric care. The experience of HIV advocates in pushing for global solutions based on right to health principles, including participation, solidarity and accountability; suggest potential avenues for utilising right to health based arguments to push for policy priority for universal access to emergency obstetric care in the post-2015 global agenda.

Shared Rights--Shared Responsibilities. European Consultation on Collaboration between Government Sectors, Nongovernmental Organizations and Ethnic Minority Organizations in AIDS Prevention, Support and Care (London, United Kingdom, October 5-9, 1995).

ERIC Educational Resources Information Center

Naz Foundation, London (England).

A consultation was sponsored by the European Commission, the World Health Organization's Global Programme on AIDS, and the United Kingdom Department of Health to explore the specific needs of ethnic minority communities in European countries for culturally and linguistically appropriate Human Immunodeficiency Virus (HIV) and Acquired Immune…

77 FR 18266 - Meeting of the Department of Justice Global Justice Information Sharing Initiative Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... Department of Justice Global Justice Information Sharing Initiative Federal Advisory Committee AGENCY: Office... meeting of the Department of Justice (DOJ) Global Justice Information Sharing Initiative (Global) Federal Advisory Committee (GAC) to discuss the Global Initiative, as described at www.it.ojp.gov/global . DATES...

Full circumpolar migration ensures evolutionary unity in the Emperor penguin.

PubMed

Cristofari, Robin; Bertorelle, Giorgio; Ancel, André; Benazzo, Andrea; Le Maho, Yvon; Ponganis, Paul J; Stenseth, Nils Chr; Trathan, Phil N; Whittington, Jason D; Zanetti, Enrico; Zitterbart, Daniel P; Le Bohec, Céline; Trucchi, Emiliano

2016-06-14

Defining reliable demographic models is essential to understand the threats of ongoing environmental change. Yet, in the most remote and threatened areas, models are often based on the survey of a single population, assuming stationarity and independence in population responses. This is the case for the Emperor penguin Aptenodytes forsteri, a flagship Antarctic species that may be at high risk continent-wide before 2100. Here, using genome-wide data from the whole Antarctic continent, we reveal that this top-predator is organized as one single global population with a shared demography since the late Quaternary. We refute the view of the local population as a relevant demographic unit, and highlight that (i) robust extinction risk estimations are only possible by including dispersal rates and (ii) colony-scaled population size is rather indicative of local stochastic events, whereas the species' response to global environmental change is likely to follow a shared evolutionary trajectory.

Full circumpolar migration ensures evolutionary unity in the Emperor penguin

PubMed Central

Cristofari, Robin; Bertorelle, Giorgio; Ancel, André; Benazzo, Andrea; Le Maho, Yvon; Ponganis, Paul J.; Stenseth, Nils Chr; Trathan, Phil N.; Whittington, Jason D.; Zanetti, Enrico; Zitterbart, Daniel P.; Le Bohec, Céline; Trucchi, Emiliano

2016-01-01

Defining reliable demographic models is essential to understand the threats of ongoing environmental change. Yet, in the most remote and threatened areas, models are often based on the survey of a single population, assuming stationarity and independence in population responses. This is the case for the Emperor penguin Aptenodytes forsteri, a flagship Antarctic species that may be at high risk continent-wide before 2100. Here, using genome-wide data from the whole Antarctic continent, we reveal that this top-predator is organized as one single global population with a shared demography since the late Quaternary. We refute the view of the local population as a relevant demographic unit, and highlight that (i) robust extinction risk estimations are only possible by including dispersal rates and (ii) colony-scaled population size is rather indicative of local stochastic events, whereas the species' response to global environmental change is likely to follow a shared evolutionary trajectory. PMID:27296726

The Collaboration Challenge: Global Partnerships to Achieve Global Goals.

PubMed

Bzdak, Michael

2017-01-01

As capitalism is being re-invented and the voices of multiple stakeholders are becoming more prevalent and demanding, it is the perfect time for the private sector to embrace large-scale collaboration and a shared sense of purpose. Since the explosive growth of Corporate Social Responsibility (CSR) in the 1990s, a new era of responsibility, purpose and a re-envisioned capitalism are dramatically apparent. Beyond financial support, business leaders have the opportunity to galvanize networks, advocate for regulation and policy change, and form supporting consortia to support global development. The role of the private sector in development has changed significantly from a model of benevolent contributor to a model of collaborator, investor, business partner and exponential value creator. The new era of collaboration should move beyond a shared value mindset to new models of partnership where each contributor plays an equal role in defining challenges and designing solutions with the greater goal of sustainable value creation. Non-Governmental Organizations (NGOs) have the unprecedented opportunity to take leadership roles in engaging the private sector in more game-changing collaborations.

Facilitating a culture of responsible and effective sharing of cancer genome data.

PubMed

Siu, Lillian L; Lawler, Mark; Haussler, David; Knoppers, Bartha Maria; Lewin, Jeremy; Vis, Daniel J; Liao, Rachel G; Andre, Fabrice; Banks, Ian; Barrett, J Carl; Caldas, Carlos; Camargo, Anamaria Aranha; Fitzgerald, Rebecca C; Mao, Mao; Mattison, John E; Pao, William; Sellers, William R; Sullivan, Patrick; Teh, Bin Tean; Ward, Robyn L; ZenKlusen, Jean Claude; Sawyers, Charles L; Voest, Emile E

2016-05-05

Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance the diagnosis, prognostication and treatment of cancer. A critical point has now been reached at which the analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers to data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data-aggregation challenges faced by the field, suggests potential collaborative solutions and describes how GA4GH can catalyze a harmonized data-sharing culture.

International Global Crop Condition Assessments in the framework of GEOGLAM

NASA Astrophysics Data System (ADS)

Becker-Reshef, I.; Justice, C. O.; Vermote, E.; Whitcraft, A. K.; Claverie, M.

2013-12-01

The Group on Earth Observations (partnership of governments and international organizations) developed the Global Agricultural Monitoring (GEOGLAM) initiative in response to the growing calls for improved agricultural information. The goal of GEOGLAM is to strengthen the international community's capacity to produce and disseminate relevant, timely and accurate forecasts of agricultural production at national, regional and global scales through the use of Earth observations. This initiative is designed to build on existing agricultural monitoring initiatives at national, regional and global levels and to enhance and strengthen them through international networking, operationally focused research, and data/method sharing. GEOGLAM was adopted by the G20 as part of the action plan on food price volatility and agriculture and is being implemented through building on the extensive GEO Agricultural Community of Practice (CoP) that was initiated in 2007 and includes key national and international agencies, organizations, and universities involved in agricultural monitoring. One of the early GEOGLAM activities is to provide harmonized global crop outlooks that offer timely qualitative consensus information on crop status and prospects. This activity is being developed in response to a request from the G-20 Agricultural Market Information System (AMIS) and is implemented within the global monitoring systems component of GEOGLAM. The goal is to develop a transparent, international, multi-source, consensus assessment of crop growing conditions, status, and agro-climatic conditions, likely to impact global production. These assessments are focused on the four primary crop types (corn, wheat, soy and rice) within the main agricultural producing regions of the world. The GEOGLAM approach is to bring together international experts from global, regional and national monitoring systems that can share and discuss information from a variety of independent complementary sources in order to reach a convergence of evidence based assessment. Information types include earth observations (EO) data and products, agro-meteorological data, crop models and field reports. To date, representatives from close to 20 different agencies have participated in these outlook assessments, which are submitted to AMIS on a monthly basis as well as shared with the international community. This talk will discuss the process, operational R&D, and progress towards developing these harmonized global crop assessments.

Developing a Strategic Approach to Social Responsiveness at the University of Cape Town, South Africa

ERIC Educational Resources Information Center

Favish, Judith; McMillan, Janice; Ngcelwane, Sonwabo V.

2012-01-01

Collaborative community-engaged scholarship has roots in many parts of the world, and engaged practitioners and researchers are increasingly finding each other and sharing resources globally. This article focuses on a "social responsiveness" initiative at the University of Cape Town. Its story, told here by three University of Cape Town…

The Tension Between Data Sharing and the Protection of Privacy in Genomics Research

PubMed Central

Kaye, Jane

2014-01-01

Next-generation sequencing and global data sharing challenge many of the governance mechanisms currently in place to protect the privacy of research participants. These challenges will make it more difficult to guarantee anonymity for participants, provide information to satisfy the requirements of informed consent, and ensure complete withdrawal from research when requested. To move forward, we need to improve the current governance systems for research so that they are responsive to individual privacy concerns but can also be effective at a global level. We need to develop a system of e-governance that can complement existing governance systems but that places greater reliance on the use of technology to ensure compliance with ethical and legal requirements. These new governance structures must be able to address the concerns of research participants while at the same time ensuring effective data sharing that promotes public trust in genomics research. PMID:22404490

The tension between data sharing and the protection of privacy in genomics research.

PubMed

Kaye, Jane

2012-01-01

Next-generation sequencing and global data sharing challenge many of the governance mechanisms currently in place to protect the privacy of research participants. These challenges will make it more difficult to guarantee anonymity for participants, provide information to satisfy the requirements of informed consent, and ensure complete withdrawal from research when requested. To move forward, we need to improve the current governance systems for research so that they are responsive to individual privacy concerns but can also be effective at a global level. We need to develop a system of e-governance that can complement existing governance systems but that places greater reliance on the use of technology to ensure compliance with ethical and legal requirements. These new governance structures must be able to address the concerns of research participants while at the same time ensuring effective data sharing that promotes public trust in genomics research.

The Global File System

NASA Technical Reports Server (NTRS)

Soltis, Steven R.; Ruwart, Thomas M.; OKeefe, Matthew T.

1996-01-01

The global file system (GFS) is a prototype design for a distributed file system in which cluster nodes physically share storage devices connected via a network-like fiber channel. Networks and network-attached storage devices have advanced to a level of performance and extensibility so that the previous disadvantages of shared disk architectures are no longer valid. This shared storage architecture attempts to exploit the sophistication of storage device technologies whereas a server architecture diminishes a device's role to that of a simple component. GFS distributes the file system responsibilities across processing nodes, storage across the devices, and file system resources across the entire storage pool. GFS caches data on the storage devices instead of the main memories of the machines. Consistency is established by using a locking mechanism maintained by the storage devices to facilitate atomic read-modify-write operations. The locking mechanism is being prototyped in the Silicon Graphics IRIX operating system and is accessed using standard Unix commands and modules.

Civil society organizations, the implementing partners of the Global Vaccine Action Plan.

PubMed

Thacker, Naveen; Vashishtha, Vipin M; Awunyo-Akaba, Joan; Mistry, Rozina Farhad

2013-04-18

The authors illustrate by way of civil society (CS) experiences in Pakistan, India, and Ghana how the guiding principles of CS and civil society organizations (CSOs) align with those of the Global Vaccine Action Plan (GVAP); (i.e., country ownership, shared responsibility and partnership, equity, integration, sustainability, and innovation). These experiences show how CS is contributing to GVAP goals such as global polio eradication and improving vaccination coverage by removing barriers and ultimately working toward achieving Millennium Development Goal (MDG) 4-reducing child mortality. A number of CSOs working in the field of child health share some of the objectives enlisted in GVAP: that immunization becomes a national health priority; individuals, families, communities understand the importance of immunization; benefits of immunization are equitably extended to all people; and vaccination systems are part of an integrated health system. Copyright © 2012 Elsevier Ltd. All rights reserved.

Integrating Genome-based Informatics to Modernize Global Disease Monitoring, Information Sharing, and Response

PubMed Central

Brown, Eric W.; Detter, Chris; Gerner-Smidt, Peter; Gilmour, Matthew W.; Harmsen, Dag; Hendriksen, Rene S.; Hewson, Roger; Heymann, David L.; Johansson, Karin; Ijaz, Kashef; Keim, Paul S.; Koopmans, Marion; Kroneman, Annelies; Wong, Danilo Lo Fo; Lund, Ole; Palm, Daniel; Sawanpanyalert, Pathom; Sobel, Jeremy; Schlundt, Jørgen

2012-01-01

The rapid advancement of genome technologies holds great promise for improving the quality and speed of clinical and public health laboratory investigations and for decreasing their cost. The latest generation of genome DNA sequencers can provide highly detailed and robust information on disease-causing microbes, and in the near future these technologies will be suitable for routine use in national, regional, and global public health laboratories. With additional improvements in instrumentation, these next- or third-generation sequencers are likely to replace conventional culture-based and molecular typing methods to provide point-of-care clinical diagnosis and other essential information for quicker and better treatment of patients. Provided there is free-sharing of information by all clinical and public health laboratories, these genomic tools could spawn a global system of linked databases of pathogen genomes that would ensure more efficient detection, prevention, and control of endemic, emerging, and other infectious disease outbreaks worldwide. PMID:23092707

The global dimensions of public health preparedness and implications for US action.

PubMed

Moore, Melinda

2012-06-01

The globalization of public health is both real and relevant throughout the United States and to Americans traveling or residing abroad. US public policy responses are evolving, but a crisper and more comprehensive global perspective is needed. I suggest four timely US actions to address today's competing realities of globalization and economic austerity: raise awareness among clinicians and local health departments; capture and share exemplary disaster management practices across countries; ensure that US global health investments are effective, efficient, and sustainable; and think globally while acting locally to enhance US health security. The reauthorization of the Pandemic and All-Hazards Preparedness Act of 2006 provides an opportunity to more clearly address the global dimensions of domestic preparedness.

78 FR 17232 - Meeting of the Global Justice Information Sharing Initiative Federal Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-20

... DEPARTMENT OF JUSTICE Office of Justice Programs [OJP (BJA) Docket No. 1616] Meeting of the Global Justice Information Sharing Initiative Federal Advisory Committee AGENCY: Office of Justice Programs (OJP... Information Sharing Initiative (Global) Federal Advisory Committee (GAC) to discuss the Global Initiative, as...

All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health.

PubMed

Lawler, Mark; Siu, Lillian L; Rehm, Heidi L; Chanock, Stephen J; Alterovitz, Gil; Burn, John; Calvo, Fabien; Lacombe, Denis; Teh, Bin Tean; North, Kathryn N; Sawyers, Charles L

2015-11-01

The recent explosion of genetic and clinical data generated from tumor genome analysis presents an unparalleled opportunity to enhance our understanding of cancer, but this opportunity is compromised by the reluctance of many in the scientific community to share datasets and the lack of interoperability between different data platforms. The Global Alliance for Genomics and Health is addressing these barriers and challenges through a cooperative framework that encourages "team science" and responsible data sharing, complemented by the development of a series of application program interfaces that link different data platforms, thus breaking down traditional silos and liberating the data to enable new discoveries and ultimately benefit patients. ©2015 American Association for Cancer Research.

'Preparing ourselves to become an international organization': Thailand Tobacco Monopoly's regional and global strategies.

PubMed

MacKenzie, Ross; Ross, Hana; Lee, Kelley

2017-03-01

The Thailand Tobacco Monopoly (TTM) controlled the country's tobacco industry from its formation in the 1940s, until the government dropped restrictions on imported cigarettes in the late 1980s in response to pressure from the United States. The TTM has since competed with transnational tobacco companies (TTCs) in a semi-monopoly market in which TTCs have steadily increased their market share. Coupled with a decline in national smoking prevalence, the result of Thailand's stringent tobacco control agenda, the TTM now accounts for a diminishing share of a contracting market. In response, the monopoly has looked to regional trade liberalisation, and proximity to markets with some of the world's highest smoking rates to expand its operations. Expansion strategies have gone largely unrealised however, and the TTM effectively remains a domestic operation. Using TTM publications, market and trade reports, industry publications, tobacco industry documents and other resources, this paper analyses TTM expansion strategies, and the limited extent to which they have been achieved. This inability to expand its operations has left the monopoly potentially vulnerable to global strategies of its transnational competitors. This article is part of the special issue 'The Emergence of Asian Tobacco Companies: Implications for Global Health Governance'.

The emergence of a global right to health norm – the unresolved case of universal access to quality emergency obstetric care

PubMed Central

2014-01-01

Background The global response to HIV suggests the potential of an emergent global right to health norm, embracing shared global responsibility for health, to assist policy communities in framing the obligations of the domestic state and the international community. Our research explores the extent to which this global right to health norm has influenced the global policy process around maternal health rights, with a focus on universal access to emergency obstetric care. Methods In examining the extent to which arguments stemming from a global right to health norm have been successful in advancing international policy on universal access to emergency obstetric care, we looked at the period from 1985 to 2013 period. We adopted a qualitative case study approach applying a process-tracing methodology using multiple data sources, including an extensive literature review and limited key informant interviews to analyse the international policy agenda setting process surrounding maternal health rights, focusing on emergency obstetric care. We applied John Kingdon's public policy agenda setting streams model to analyse our data. Results Kingdon’s model suggests that to succeed as a mobilising norm, the right to health could work if it can help bring the problem, policy and political streams together, as it did with access to AIDS treatment. Our analysis suggests that despite a normative grounding in the right to health, prioritisation of the specific maternal health entitlements remains fragmented. Conclusions Despite United Nations recognition of maternal mortality as a human rights issue, the relevant policy communities have not yet managed to shift the policy agenda to prioritise the global right to health norm of shared responsibility for realising access to emergency obstetric care. The experience of HIV advocates in pushing for global solutions based on right to health principles, including participation, solidarity and accountability; suggest potential avenues for utilising right to health based arguments to push for policy priority for universal access to emergency obstetric care in the post-2015 global agenda. PMID:24576008

Equilibrium drives of the low and high field side n = 2 plasma response and impact on global confinement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paz-Soldan, C.; Logan, N. C.; Haskey, S. R.

The nature of the multi-modal n=2 plasma response and its impact on global confinement is studied as a function of the axisymmetric equilibrium pressure, edge safety factor, collisionality, and L-versus H-mode conditions. Varying the relative phase (ΔΦ UL) between upper and lower in-vessel coils demonstrates that different n=2 poloidal spectra preferentially excite different plasma responses. These different plasma response modes are preferentially detected on the tokamak high-field side (HFS) or low-field side (LFS) midplanes, have different radial extents, couple differently to the resonant surfaces, and have variable impacts on edge stability and global confinement. In all equilibrium conditions studied, themore » observed confinement degradation shares the same ΔΦ UL dependence as the coupling to the resonant surfaces given by both ideal (IPEC) and resistive (MARS-F) MHD computation. Varying the edge safety factor shifts the equilibrium field-line pitch and thus the ΔΦ UL dependence of both the global confinement and the n=2 magnetic response. As edge safety factor is varied, modeling finds that the HFS response (but not the LFS response), the resonant surface coupling, and the edge displacements near the X-point all share the same ΔΦ UL dependence. The LFS response magnitude is strongly sensitive to the core pressure and is insensitive to the collisionality and edge safety factor. This indicates that the LFS measurements are primarily sensitive to a pressure-driven kink-ballooning mode that couples to the core plasma. MHD modeling accurately reproduces these (and indeed all) LFS experimental trends and supports this interpretation. In contrast to the LFS, the HFS magnetic response and correlated global confinement impact is unchanged with plasma pressure, but is strongly reduced in high collisionality conditions in both H- and L-mode. This experimentally suggests the bootstrap current drives the HFS response through the kink-peeling mode drive, though surprisingly weak or no dependence on the bootstrap current is seen in modeling. Instead, modeling is revealed to be very sensitive to the details of the edge current profile and equilibrium truncation. Furthermore, holding truncation fixed, most HFS experimental trends are not captured, thus demonstrating a stark contrast between the robustness of the HFS experimental results and the sensitivity of its computation.« less

Equilibrium drives of the low and high field side n  =  2 plasma response and impact on global confinement

NASA Astrophysics Data System (ADS)

Paz-Soldan, C.; Logan, N. C.; Haskey, S. R.; Nazikian, R.; Strait, E. J.; Chen, X.; Ferraro, N. M.; King, J. D.; Lyons, B. C.; Park, J.-K.

2016-05-01

The nature of the multi-modal n  =  2 plasma response and its impact on global confinement is studied as a function of the axisymmetric equilibrium pressure, edge safety factor, collisionality, and L-versus H-mode conditions. Varying the relative phase (Δ {φ\\text{UL}} ) between upper and lower in-vessel coils demonstrates that different n  =  2 poloidal spectra preferentially excite different plasma responses. These different plasma response modes are preferentially detected on the tokamak high-field side (HFS) or low-field side (LFS) midplanes, have different radial extents, couple differently to the resonant surfaces, and have variable impacts on edge stability and global confinement. In all equilibrium conditions studied, the observed confinement degradation shares the same Δ {φ\\text{UL}} dependence as the coupling to the resonant surfaces given by both ideal (IPEC) and resistive (MARS-F) MHD computation. Varying the edge safety factor shifts the equilibrium field-line pitch and thus the Δ {φ\\text{UL}} dependence of both the global confinement and the n  =  2 magnetic response. As edge safety factor is varied, modeling finds that the HFS response (but not the LFS response), the resonant surface coupling, and the edge displacements near the X-point all share the same Δ {φ\\text{UL}} dependence. The LFS response magnitude is strongly sensitive to the core pressure and is insensitive to the collisionality and edge safety factor. This indicates that the LFS measurements are primarily sensitive to a pressure-driven kink-ballooning mode that couples to the core plasma. MHD modeling accurately reproduces these (and indeed all) LFS experimental trends and supports this interpretation. In contrast to the LFS, the HFS magnetic response and correlated global confinement impact is unchanged with plasma pressure, but is strongly reduced in high collisionality conditions in both H- and L-mode. This experimentally suggests the bootstrap current drives the HFS response through the kink-peeling mode drive, though surprisingly weak or no dependence on the bootstrap current is seen in modeling. Instead, modeling is revealed to be very sensitive to the details of the edge current profile and equilibrium truncation. Holding truncation fixed, most HFS experimental trends are not captured, thus demonstrating a stark contrast between the robustness of the HFS experimental results and the sensitivity of its computation.

Equilibrium drives of the low and high field side n = 2 plasma response and impact on global confinement

DOE PAGES

Paz-Soldan, C.; Logan, N. C.; Haskey, S. R.; ...

2016-03-31

The nature of the multi-modal n=2 plasma response and its impact on global confinement is studied as a function of the axisymmetric equilibrium pressure, edge safety factor, collisionality, and L-versus H-mode conditions. Varying the relative phase (ΔΦ UL) between upper and lower in-vessel coils demonstrates that different n=2 poloidal spectra preferentially excite different plasma responses. These different plasma response modes are preferentially detected on the tokamak high-field side (HFS) or low-field side (LFS) midplanes, have different radial extents, couple differently to the resonant surfaces, and have variable impacts on edge stability and global confinement. In all equilibrium conditions studied, themore » observed confinement degradation shares the same ΔΦ UL dependence as the coupling to the resonant surfaces given by both ideal (IPEC) and resistive (MARS-F) MHD computation. Varying the edge safety factor shifts the equilibrium field-line pitch and thus the ΔΦ UL dependence of both the global confinement and the n=2 magnetic response. As edge safety factor is varied, modeling finds that the HFS response (but not the LFS response), the resonant surface coupling, and the edge displacements near the X-point all share the same ΔΦ UL dependence. The LFS response magnitude is strongly sensitive to the core pressure and is insensitive to the collisionality and edge safety factor. This indicates that the LFS measurements are primarily sensitive to a pressure-driven kink-ballooning mode that couples to the core plasma. MHD modeling accurately reproduces these (and indeed all) LFS experimental trends and supports this interpretation. In contrast to the LFS, the HFS magnetic response and correlated global confinement impact is unchanged with plasma pressure, but is strongly reduced in high collisionality conditions in both H- and L-mode. This experimentally suggests the bootstrap current drives the HFS response through the kink-peeling mode drive, though surprisingly weak or no dependence on the bootstrap current is seen in modeling. Instead, modeling is revealed to be very sensitive to the details of the edge current profile and equilibrium truncation. Furthermore, holding truncation fixed, most HFS experimental trends are not captured, thus demonstrating a stark contrast between the robustness of the HFS experimental results and the sensitivity of its computation.« less

77 FR 70805 - Presquile National Wildlife Refuge, Chesterfield County, VA; Final Comprehensive Conservation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

... opportunities, including environmental education programs for approximately 120 school-aged students each year... species, protect cultural resources, monitor for climate change impacts, distribute refuge revenue sharing..., and a more aggressive response to habitat changes associated with invasive species, global climate...

Dataworks for GNSS: Software for Supporting Data Sharing and Federation of Geodetic Networks

NASA Astrophysics Data System (ADS)

Boler, F. M.; Meertens, C. M.; Miller, M. M.; Wier, S.; Rost, M.; Matykiewicz, J.

2015-12-01

Continuously-operating Global Navigation Satellite System (GNSS) networks are increasingly being installed globally for a wide variety of science and societal applications. GNSS enables Earth science research in areas including tectonic plate interactions, crustal deformation in response to loading by tectonics, magmatism, water and ice, and the dynamics of water - and thereby energy transfer - in the atmosphere at regional scale. The many individual scientists and organizations that set up GNSS stations globally are often open to sharing data, but lack the resources or expertise to deploy systems and software to manage and curate data and metadata and provide user tools that would support data sharing. UNAVCO previously gained experience in facilitating data sharing through the NASA-supported development of the Geodesy Seamless Archive Centers (GSAC) open source software. GSAC provides web interfaces and simple web services for data and metadata discovery and access, supports federation of multiple data centers, and simplifies transfer of data and metadata to long-term archives. The NSF supported the dissemination of GSAC to multiple European data centers forming the European Plate Observing System. To expand upon GSAC to provide end-to-end, instrument-to-distribution capability, UNAVCO developed Dataworks for GNSS with NSF funding to the COCONet project, and deployed this software on systems that are now operating as Regional GNSS Data Centers as part of the NSF-funded TLALOCNet and COCONet projects. Dataworks consists of software modules written in Python and Java for data acquisition, management and sharing. There are modules for GNSS receiver control and data download, a database schema for metadata, tools for metadata handling, ingest software to manage file metadata, data file management scripts, GSAC, scripts for mirroring station data and metadata from partner GSACs, and extensive software and operator documentation. UNAVCO plans to provide a cloud VM image of Dataworks that would allow standing up a Dataworks-enabled GNSS data center without requiring upfront investment in server hardware. By enabling data creators to organize their data and metadata for sharing, Dataworks helps scientists expand their data curation awareness and responsibility, and enhances data access for all.

A global picture of biological invasion threat on islands.

PubMed

Bellard, Céline; Rysman, Jean-François; Leroy, Boris; Claud, Chantal; Mace, Georgina M

2017-12-01

Biological invasions are among the main drivers of biodiversity losses. As threats from biological invasions increase, one of the most urgent tasks is to identify areas of high vulnerability. However, the lack of comprehensive information on the impacts of invasive alien species (IAS) is a problem especially on islands, where most of the recorded extinctions associated with IAS have occurred. Here we provide a global, network-oriented analysis of IAS on islands. Using network analysis, we structured 27,081 islands and 437 threatened vertebrates into 21 clusters, based on their profiles in term of invasiveness and shared vulnerabilities. These islands are mainly located in the Southern Hemisphere and many are in biodiversity hotspots. Some of the islands share similar characteristics regarding their connectivity that could be useful for understanding their response to invasive species. The major invaders found in these clusters of islands are feral cats, feral dogs, pigs and rats. Our analyses reveal those IAS that systematically act alone or in combination, and the pattern of shared IAS among threatened species, providing new information to implement effective eradication strategies. Combined with further local, contextual information this can contribute to global strategies to deal with IAS.

What Do the Various Principles of Justice Mean Within the Concept of Benefit Sharing?

PubMed

Dauda, Bege; Denier, Yvonne; Dierickx, Kris

2016-06-01

The concept of benefit sharing pertains to the act of giving something in return to the participants, communities, and the country that have participated in global health research or bioprospecting activities. One of the key concerns of benefit sharing is the ethical justifications or reasons to support the practice of the concept in global health research and bioprospecting. This article evaluates one of such ethical justifications and its meaning to benefit sharing, namely justice. We conducted a systematic review to map the various principles of justice that are linked to benefit sharing and analysed their meaning to the concept of benefit sharing. Five principles of justice (commutative, distributive, global, procedural, and compensatory) have been shown to be relevant in the nuances of benefit sharing in both global health research and bioprospecting. The review findings indicate that each of these principles of justice provides a different perspective for a different benefit sharing rationale. For example, commutative justice provides a benefit sharing rationale that is focused on fair exchange of benefits between research sponsors and communities. Distributive justice produces a benefit sharing rationale that is focused on improving the health needs of the vulnerable research communities. We have suggested that a good benefit sharing framework particularly in global health research would be more beneficial if it combines all the principles of justice in its formulation. Nonetheless, there is a need for empirical studies to examine the various principles of justice and their nuances in benefit sharing among stakeholders in global health research.

Integrating biodiversity management and indigenous biopiracy protection to promote environmental justice and global health.

PubMed

Mackey, Tim K; Liang, Bryan A

2012-06-01

Many potentially useful medicines arise from developing countries' biodiverse environments and indigenous knowledge. However, global intellectual property rules have resulted in biopiracy, raising serious ethical concerns of environmental justice, exploitation, and health disparities in these populations. Furthermore, state-based approaches have not led to adequate biodiversity protection, management, or resource sharing, which affect access to lifesaving drugs. In response, country delegates adopted the Nagoya Protocol, which aims at promoting biodiversity management, combating biopiracy, and encouraging equitable benefits sharing with indigenous communities. However, the effectiveness of this framework in meeting these objectives remains in question. To address these challenges, we propose a policy building on the Nagoya Protocol that employs a World Health Organization-World Trade Organization Joint Committee on Bioprospecting and Biopiracy.

Practicing Culturally Responsive Pedagogy in Physical Education

ERIC Educational Resources Information Center

Young, Shawna; Sternod, Brandon M.

2011-01-01

As a result of continuous global immigration to the United States, several microcultures coexist within the country. Today's classroom should provide an interface where individuals from different cultural backgrounds have the potential for sharing a rich place of learning--a place where the teacher embraces and celebrates individual differences,…

Going Green: Empowering Readers to Change the Environment

ERIC Educational Resources Information Center

Napoli, Mary

2011-01-01

Educators have a shared responsibility to encourage youth to take positive action that can have an environmental impact both locally and globally. The North American Association for Environmental Education ([NAAEE] 2004) has stressed the importance of increasing environmental knowledge among teachers, by participating in in-service programs or…

Ranavirus: past, present, and future

Treesearch

D. Lesbarreres; A. Balseiro; J. Brunner; V.G. Chinchar; A. Duffus; J. Kerby; D.L. Miller; J. Robert; D.M. Schock; T. Waltzek; M.J. Gray

2011-01-01

Emerging infectious diseases are a significant threat to global biodiversity. While historically overlooked, a group of iridoviruses in the genus Ranavirus has been responsible for die-offs in captive and wild amphibian, reptile and fish populations around the globe over the past two decades. In order to share contemporary information on...

Involving Research Stakeholders in Developing Policy on Sharing Public Health Research Data in Kenya

PubMed Central

Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy

2015-01-01

Increased global sharing of public health research data has potential to advance scientific progress but may present challenges to the interests of research stakeholders, particularly in low-to-middle income countries. Policies for data sharing should be responsive to public views, but there is little evidence of the systematic study of these from low-income countries. This qualitative study explored views on fair data-sharing processes among 60 stakeholders in Kenya with varying research experience, using a deliberative approach. Stakeholders’ attitudes were informed by perceptions of benefit and concerns for research data sharing, including risks of stigmatization, loss of privacy, and undermining scientific careers and validity, reported in detail elsewhere. In this article, we discuss institutional trust-building processes seen as central to perceptions of fairness in sharing research data in this setting, including forms of community involvement, individual prior awareness and agreement to data sharing, independence and accountability of governance mechanisms, and operating under a national framework. PMID:26297748

Sharing health-related data: a privacy test?

PubMed Central

Dyke, Stephanie OM; Dove, Edward S; Knoppers, Bartha M

2016-01-01

Greater sharing of potentially sensitive data raises important ethical, legal and social issues (ELSI), which risk hindering and even preventing useful data sharing if not properly addressed. One such important issue is respecting the privacy-related interests of individuals whose data are used in genomic research and clinical care. As part of the Global Alliance for Genomics and Health (GA4GH), we examined the ELSI status of health-related data that are typically considered ‘sensitive’ in international policy and data protection laws. We propose that ‘tiered protection’ of such data could be implemented in contexts such as that of the GA4GH Beacon Project to facilitate responsible data sharing. To this end, we discuss a Data Sharing Privacy Test developed to distinguish degrees of sensitivity within categories of data recognised as ‘sensitive’. Based on this, we propose guidance for determining the level of protection when sharing genomic and health-related data for the Beacon Project and in other international data sharing initiatives. PMID:27990299

WHO-REMPAN for global health security and strengthening preparedness and response to radiation emergencies.

PubMed

Carr, Zhanat

2010-06-01

In response to the changing global environment and emerging new issues related to health security, the World Health Organization (WHO) is putting in place new tools for collective defense, such as the revised International Health Regulations (IHR) (2005). The new framework puts additional responsibilities on both Member States and WHO itself in order to effectively implement the IHR (2005) and react effectively in case of public health emergency events of any nature. Since its establishment in 1987, the Radiation Emergency Medical Preparedness and Assistance Network of WHO (WHO-REMPAN) has become an important asset for the organization's capacity to respond to radiation emergencies and to assist its Member States to strengthen their own response capacities. The paper describes in detail the framework for the WHO's role in preparedness and response to radiation emergencies, including Emergency Conventions and IHR (2005), and how the WHO-REMPAN, through its activities (i.e., technical guidelines development, training, education, research, and information sharing), provides a significant contribution to the organization's program of work towards achievement of the global health security goal.

‘Preparing ourselves to become an international organization’: Thailand Tobacco Monopoly’s regional and global strategies

PubMed Central

MacKenzie, Ross; Ross, Hana; Lee, Kelley

2017-01-01

ABSTRACT The Thailand Tobacco Monopoly (TTM) controlled the country’s tobacco industry from its formation in the 1940s, until the government dropped restrictions on imported cigarettes in the late 1980s in response to pressure from the United States. The TTM has since competed with transnational tobacco companies (TTCs) in a semi-monopoly market in which TTCs have steadily increased their market share. Coupled with a decline in national smoking prevalence, the result of Thailand’s stringent tobacco control agenda, the TTM now accounts for a diminishing share of a contracting market. In response, the monopoly has looked to regional trade liberalisation, and proximity to markets with some of the world’s highest smoking rates to expand its operations. Expansion strategies have gone largely unrealised however, and the TTM effectively remains a domestic operation. Using TTM publications, market and trade reports, industry publications, tobacco industry documents and other resources, this paper analyses TTM expansion strategies, and the limited extent to which they have been achieved. This inability to expand its operations has left the monopoly potentially vulnerable to global strategies of its transnational competitors. This article is part of the special issue ‘The Emergence of Asian Tobacco Companies: Implications for Global Health Governance’. PMID:28139965

Ethics and governance of global health inequalities

PubMed Central

Ruger, J P

2006-01-01

Background A world divided by health inequalities poses ethical challenges for global health. International and national responses to health disparities must be rooted in ethical values about health and its distribution; this is because ethical claims have the power to motivate, delineate principles, duties and responsibilities, and hold global and national actors morally responsible for achieving common goals. Theories of justice are necessary to define duties and obligations of institutions and actors in reducing inequalities. The problem is the lack of a moral framework for solving problems of global health justice. Aim To study why global health inequalities are morally troubling, why efforts to reduce them are morally justified, how they should be measured and evaluated; how much priority disadvantaged groups should receive; and to delineate roles and responsibilities of national and international actors and institutions. Discussion and conclusions Duties and obligations of international and state actors in reducing global health inequalities are outlined. The ethical principles endorsed include the intrinsic value of health to well‐being and equal respect for all human life, the importance of health for individual and collective agency, the concept of a shortfall from the health status of a reference group, and the need for a disproportionate effort to help disadvantaged groups. This approach does not seek to find ways in which global and national actors address global health inequalities by virtue of their self‐interest, national interest, collective security or humanitarian assistance. It endorses the more robust concept of “human flourishing” and the desire to live in a world where all people have the capability to be healthy. Unlike cosmopolitan theory, this approach places the role of the nation‐state in the forefront with primary, though not sole, moral responsibility. Rather shared health governance is essential for delivering health equity on a global scale. PMID:17053290

Data sharing as social dilemma: Influence of the researcher’s personality

PubMed Central

2017-01-01

It is widely acknowledged that data sharing has great potential for scientific progress. However, so far making data available has little impact on a researcher’s reputation. Thus, data sharing can be conceptualized as a social dilemma. In the presented study we investigated the influence of the researcher's personality within the social dilemma of data sharing. The theoretical background was the appropriateness framework. We conducted a survey among 1564 researchers about data sharing, which also included standardized questions on selected personality factors, namely the so-called Big Five, Machiavellianism and social desirability. Using regression analysis, we investigated how these personality domains relate to four groups of dependent variables: attitudes towards data sharing, the importance of factors that might foster or hinder data sharing, the willingness to share data, and actual data sharing. Our analyses showed the predictive value of personality for all four groups of dependent variables. However, there was not a global consistent pattern of influence, but rather different compositions of effects. Our results indicate that the implications of data sharing are dependent on age, gender, and personality. In order to foster data sharing, it seems advantageous to provide more personal incentives and to address the researchers’ individual responsibility. PMID:28817642

Promoting European Dimensions in Lifelong Learning.

ERIC Educational Resources Information Center

Field, John, Ed.

This collection of 19 essays shares the lessons of a wealth of experience and challenges professionals to open up adult learning to a variety of international perspectives. The first essay, "Building a European Dimension: A Realistic Response to Globalization?" (John Field), is an introduction to the essays. The six essays in Section I,…

Ready for the Storm: Education for Disaster Risk Reduction and Climate Change Adaptation and Mitigation

ERIC Educational Resources Information Center

Kagawa, Fumiyo; Selby, David

2012-01-01

Incidences of disaster and climate change impacts are rising globally. Disaster risk reduction and climate change education are two educational responses to present and anticipated increases in the severity and frequency of hazards. They share significant complementarities and potential synergies, the latter as yet largely unexploited. Three…

Roots and Research in Urban School Gardens

ERIC Educational Resources Information Center

Gaylie, Veronica

2011-01-01

This book explores the urban school garden as a bridge between environmental action and thought. As a small-scale response to global issues around access to food and land, urban school gardens promote practical knowledge of farming as well as help renew cultural ideals of shared space and mutual support for the organic, built environment. Through…

Cultural Perspectives on Social Responsibility in Higher Education

ERIC Educational Resources Information Center

Yob, Iris M.

2016-01-01

The writers of the UNESCO document, "Rethinking education: Towards a global common good?" challenge educators to address their efforts to meet the current threats to sustainable life for all who share this planet. One way that higher education has been attempting to do this is through campus-community partnerships working to solve social…

A Call to (Link) Arms

ERIC Educational Resources Information Center

Gee, E. Gordon

2009-01-01

The transformative effect of higher education--to change individual lives and remedy global problems of all kinds--is without question and it is shared equally among individuals. Public or private, two-year, four-year, research, and liberal arts--each of the institutions has a sacred responsibility to educate the next generation of citizens and to…

Towards mutual trust, transparency and equity in virus sharing mechanism: the avian influenza case of Indonesia.

PubMed

Sedyaningsih, Endang R; Isfandari, Siti; Soendoro, Triono; Supari, Siti Fadilah

2008-06-01

As the country hardest hit by avian influenza, both in poultry and in human, Indonesia's decision to withhold samples of avian influenza virus A (H5N1) has fired up a global controversy. The objective of this paper is to describe the position taken by Indonesia in the events leading to the decision and in those conducted to resolve the situation. The sources for this paper are the Indonesian human influenza A(H5N1) case reports and study results, summaries, minutes and reports of national and international meetings of virus sharing, and other related Indonesian and WHO documents. The International Health Regulations 2005 have been applied in different ways based on different interpretations. While one party insists on the importance of free, non-conditional, virus sharing for risk assessment and risk response, Indonesia--as supported by most of the developing countries--stresses on the more basic principles such as sovereignty of a country over its biological materials, transparency of the global system, and equity between developed and developing nations. This event demonstrates the unresolved imbalance between the affluent high-tech countries and the poor agriculture-based countries. Regional, global and in-country meetings must continue to be conducted to find solutions acceptable to all.

Designing for Global Data Sharing, Designing for Educational Transformation

ERIC Educational Resources Information Center

Adams, Robin S.; Radcliffe, David; Fosmire, Michael

2016-01-01

This paper provides an example of a global data sharing project with an educational transformation agenda. This agenda shaped both the design of the shared dataset and the experience of sharing the common dataset to support multiple perspective inquiry and enable integrative and critically reflexive research-to-practice dialogue. The shared…

Benefit Sharing in a Global Context: Working Towards Solutions for Implementation.

PubMed

Hurst, Daniel J

2017-08-01

Due to the state of globalized clinical research, questions have been raised as to what, if any, benefits those who contribute to research should receive. One model for compensating research participants is "benefit sharing," and the basic premise is that, as a matter of justice, those who contribute to scientific research should share in its benefits. While incorporated into several international documents for over two decades, benefit sharing has only been sparsely implemented. This analysis begins by addressing the concept of benefit sharing, its historical development, and how it has been applied in the context of virus sharing for influenza research. The second portion of this analysis presents recommendations for ensuring benefit sharing. These recommendations are threefold: 1) an emphasis on social pressure, 2) the revision of international documents as means to ensure benefit sharing, and 3) greater collaboration between sponsor IRB and host country IRB. Because clinical research is a globalized industry, a global model will be proposed in the second that focuses on collaboration between the sponsor and host country. This collaboration is vital in order to ensure that proper forms of benefit sharing are accomplished as a matter of justice. © 2016 John Wiley & Sons Ltd.

77 FR 36599 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-19

... Change Relating to the Accuvest Global Long Short ETF (Formerly the Mars Hill Global Relative Value ETF...) applicable to, the Accuvest Global Long Short ETF (``Fund'') (formerly known as the Mars Hill Global Relative... the Exchange of shares (``Shares'') of the Mars Hill Global Relative Value ETF, a series of Advisor...

Partnering for the World's Children: Why Collaborations Are Important.

PubMed

Joshi, Paramjit T; Leventhal, Bennett L; Fuentes, Joaquin

2015-10-01

On a global scale, psychiatric disorders are among the most common of medical morbidity. Most psychiatric disorders have their onset in childhood and adolescence when prevention and early intervention can prevent a lifetime of suffering, disability, and stigma. Thus, we share in a global responsibility to transcend cultural and political boundaries to identify childhood-onset psychiatric illness as an international public health crisis that demands the attention and efforts of physicians and other clinicians, families, stakeholders, and policy makers around the world. Copyright © 2015 Elsevier Inc. All rights reserved.

Involving Research Stakeholders in Developing Policy on Sharing Public Health Research Data in Kenya: Views on Fair Process for Informed Consent, Access Oversight, and Community Engagement.

PubMed

Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy; Marsh, Vicki

2015-07-01

Increased global sharing of public health research data has potential to advance scientific progress but may present challenges to the interests of research stakeholders, particularly in low-to-middle income countries. Policies for data sharing should be responsive to public views, but there is little evidence of the systematic study of these from low-income countries. This qualitative study explored views on fair data-sharing processes among 60 stakeholders in Kenya with varying research experience, using a deliberative approach. Stakeholders' attitudes were informed by perceptions of benefit and concerns for research data sharing, including risks of stigmatization, loss of privacy, and undermining scientific careers and validity, reported in detail elsewhere. In this article, we discuss institutional trust-building processes seen as central to perceptions of fairness in sharing research data in this setting, including forms of community involvement, individual prior awareness and agreement to data sharing, independence and accountability of governance mechanisms, and operating under a national framework. © The Author(s) 2015.

A global social contract to reduce maternal mortality: the human rights arguments and the case of Uganda.

PubMed

Ooms, Gorik; Mulumba, Moses; Hammonds, Rachel; Latif Laila, Abdul; Waris, Attiya; Forman, Lisa

2013-11-01

Progress towards Millennium Development Goal 5a, reducing maternal deaths by 75% between 1990 and 2015, has been substantial; however, it has been too slow to hope for its achievement by 2015, particularly in sub-Saharan Africa, including Uganda. This suggests that both the Government of Uganda and the international community are failing to comply with their right-to-health-related obligations towards the people of Uganda. This country case study explores some of the key issues raised when assessing national and international right-to-health-related obligations. We argue that to comply with their shared obligations, national and international actors will have to take steps to move forward together. The Government of Uganda should not expect additional international assistance if it does not live up to its own obligations; at the same time, the international community must provide assistance that is more reliable in the long run to create the 'fiscal space' that the Government of Uganda needs to increase recurrent expenditure for health - which is crucial to addressing maternal mortality. We propose that the 'Roadmap on Shared Responsibility and Global Solidarity for AIDS, TB and Malaria Response in Africa', adopted by the African Union in July 2012, should be seen as an invitation to the international community to conclude a global social contract for health. Copyright © 2013 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

Japan Tobacco International: To 'be the most successful and respected tobacco company in the world'.

PubMed

MacKenzie, Ross; Eckhardt, Jappe; Widyati Prastyani, Ade

2017-03-01

Japan Tobacco International (JTI) is the international division of Japan Tobacco Incorporated, and the world's third largest transnational tobacco company. Founded in 1999, JTI's rapid growth has been the result of a global business strategy that potentially serves as a model for other Asian tobacco companies. This paper analyses Japan Tobacco Incorporated's global expansion since the 1980s in response to market opening, foreign competition, and declining share of a contracting domestic market. Key features of its global strategy include the on-going central role and investment by the Japanese government, and an expansion agenda based on mergers and acquisitions. The paper also discusses the challenges this global business strategy poses for global tobacco control and public health. This paper is part of the special issue 'The Emergence of Asian Tobacco Companies: Implications for Global Health Governance'.

Japan Tobacco International: To ‘be the most successful and respected tobacco company in the world’

PubMed Central

MacKenzie, Ross; Eckhardt, Jappe; Widyati Prastyani, Ade

2017-01-01

ABSTRACT Japan Tobacco International (JTI) is the international division of Japan Tobacco Incorporated, and the world’s third largest transnational tobacco company. Founded in 1999, JTI’s rapid growth has been the result of a global business strategy that potentially serves as a model for other Asian tobacco companies. This paper analyses Japan Tobacco Incorporated’s global expansion since the 1980s in response to market opening, foreign competition, and declining share of a contracting domestic market. Key features of its global strategy include the on-going central role and investment by the Japanese government, and an expansion agenda based on mergers and acquisitions. The paper also discusses the challenges this global business strategy poses for global tobacco control and public health. This paper is part of the special issue ‘The Emergence of Asian Tobacco Companies: Implications for Global Health Governance’. PMID:28139966

From Rosalind Franklin to Barack Obama: Data Sharing Challenges and Solutions in Genomics and Personalised Medicine

PubMed Central

Lawler, Mark; Maughan, Tim

2017-01-01

The collection, storage and use of genomic and clinical data from patients and healthy individuals is a key component of personalised medicine enterprises such as the Precision Medicine Initiative, the Cancer Moonshot and the 100,000 Genomes Project. In order to maximise the value of this data, it is important to embed a culture within the scientific, medical and patient communities that supports the appropriate sharing of genomic and clinical information. However, this aspiration raises a number of ethical, legal and regulatory challenges that need to be addressed. The Global Alliance for Genomics and Health, a worldwide coalition of researchers, healthcare professionals, patients and industry partners, is developing innovative solutions to support the responsible and effective sharing of genomic and clinical data. This article identifies the challenges that a data sharing culture poses and highlights a series of practical solutions that will benefit patients, researchers and society. PMID:28517986

From Rosalind Franklin to Barack Obama: Data Sharing Challenges and Solutions in Genomics and Personalised Medicine.

PubMed

Lawler, Mark; Maughan, Tim

2017-04-01

The collection, storage and use of genomic and clinical data from patients and healthy individuals is a key component of personalised medicine enterprises such as the Precision Medicine Initiative, the Cancer Moonshot and the 100,000 Genomes Project. In order to maximise the value of this data, it is important to embed a culture within the scientific, medical and patient communities that supports the appropriate sharing of genomic and clinical information. However, this aspiration raises a number of ethical, legal and regulatory challenges that need to be addressed. The Global Alliance for Genomics and Health, a worldwide coalition of researchers, healthcare professionals, patients and industry partners, is developing innovative solutions to support the responsible and effective sharing of genomic and clinical data. This article identifies the challenges that a data sharing culture poses and highlights a series of practical solutions that will benefit patients, researchers and society.

Power sharing. A transformational strategy for nurse retention, effectiveness, and extra effort.

PubMed

Trofino, Joan

2003-01-01

Power sharing with staff nurses is an essential strategy for organizational transformation. The current competitive health care environment requires a powerful team of participants, including staff at all levels, to provide health care in mutual partnership. The challenges of today's competitive and global environment call for collegial relationships among nurse executive leadership, middle nurse managers, and staff nurses. Research has demonstrated that middle nurse managers maintain primary responsibility for staff nurse retention. A higher retention rate was reported among nurses who were very satisfied with their nurse managers. Nurses considered favorably nurse managers who value staff contributions, promote information sharing, and exert influence for a stable work environment. Furthermore, as staff nurse satisfaction increased, effectiveness and extra effort also increased when staff nurses perceived transformational leadership strategies. Strategies for power sharing include serving as role models and mentors, energizing staff, resisting attitudes of staff ownership, reducing staff nurse stress of leader presence, and information sharing and commendations at meetings.

Probabilistic 21st and 22nd Century Sea-Level Projections at a Global Network of Tide-Gauge Sites

NASA Technical Reports Server (NTRS)

Kopp, Robert E.; Horton, Radley M.; Little, Christopher M.; Mitrovica, Jerry X.; Oppenheimer, Michael; Rasmussen, D. J.; Strauss, Benjamin H.; Tebaldi, Claudia

2014-01-01

Sea-level rise due to both climate change and non-climatic factors threatens coastal settlements, infrastructure, and ecosystems. Projections of mean global sea-level (GSL) rise provide insufficient information to plan adaptive responses; local decisions require local projections that accommodate different risk tolerances and time frames and that can be linked to storm surge projections. Here we present a global set of local sea-level (LSL) projections to inform decisions on timescales ranging from the coming decades through the 22nd century. We provide complete probability distributions, informed by a combination of expert community assessment, expert elicitation, and process modeling. Between the years 2000 and 2100, we project a very likely (90% probability) GSL rise of 0.5–1.2?m under representative concentration pathway (RCP) 8.5, 0.4–0.9?m under RCP 4.5, and 0.3–0.8?m under RCP 2.6. Site-to-site differences in LSL projections are due to varying non-climatic background uplift or subsidence, oceanographic effects, and spatially variable responses of the geoid and the lithosphere to shrinking land ice. The Antarctic ice sheet (AIS) constitutes a growing share of variance in GSL and LSL projections. In the global average and at many locations, it is the dominant source of variance in late 21st century projections, though at some sites oceanographic processes contribute the largest share throughout the century. LSL rise dramatically reshapes flood risk, greatly increasing the expected number of “1-in-10” and “1-in-100” year events.

Probabilistic 21st and 22nd century sea-level projections at a global network of tide-gauge sites

NASA Astrophysics Data System (ADS)

Kopp, Robert E.; Horton, Radley M.; Little, Christopher M.; Mitrovica, Jerry X.; Oppenheimer, Michael; Rasmussen, D. J.; Strauss, Benjamin H.; Tebaldi, Claudia

2014-08-01

Sea-level rise due to both climate change and non-climatic factors threatens coastal settlements, infrastructure, and ecosystems. Projections of mean global sea-level (GSL) rise provide insufficient information to plan adaptive responses; local decisions require local projections that accommodate different risk tolerances and time frames and that can be linked to storm surge projections. Here we present a global set of local sea-level (LSL) projections to inform decisions on timescales ranging from the coming decades through the 22nd century. We provide complete probability distributions, informed by a combination of expert community assessment, expert elicitation, and process modeling. Between the years 2000 and 2100, we project a very likely (90% probability) GSL rise of 0.5-1.2 m under representative concentration pathway (RCP) 8.5, 0.4-0.9 m under RCP 4.5, and 0.3-0.8 m under RCP 2.6. Site-to-site differences in LSL projections are due to varying non-climatic background uplift or subsidence, oceanographic effects, and spatially variable responses of the geoid and the lithosphere to shrinking land ice. The Antarctic ice sheet (AIS) constitutes a growing share of variance in GSL and LSL projections. In the global average and at many locations, it is the dominant source of variance in late 21st century projections, though at some sites oceanographic processes contribute the largest share throughout the century. LSL rise dramatically reshapes flood risk, greatly increasing the expected number of "1-in-10" and "1-in-100" year events.

Researching the Habitus of Global Policy Actors in Education

ERIC Educational Resources Information Center

Lingard, Bob; Sellar, Sam; Baroutsis, Aspa

2015-01-01

This paper reprises the argument for the emergence of a global education policy field and then focuses on the shared habitus of global and national policy actors and technicians. It is argued that this shared habitus is constituted as a reflection of and a contribution to the creation of the global education policy field. Bourdieu's approach to…

Linking local knowledge with global action: examining the Global Fund to Fight AIDS, Tuberculosis and Malaria through a knowledge system lens.

PubMed Central

van Kerkhoff, Lorrae; Szlezák, Nicole

2006-01-01

New global public health institutions are increasingly emphasizing transparency in decision-making, developing-country ownership of projects and programmes, and merit- and performance-based funding. Such principles imply an institutional response to the challenge of bridging the "know-do gap", by basing decisions explicitly on results, evidence and best practice. Using a knowledge systems framework, we examine how the Global Fund to Fight AIDS, Tuberculosis and Malaria has affected the ways in which knowledge is used in efforts to combat these three diseases. We outline the formal knowledge system embedded in current rules and practices associated with the Global Fund's application process, and give three examples that illustrate the complexity of the knowledge system in action: human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) policy in China; successful applications from Haiti; and responses to changing research on malaria. These examples show that the Global Fund has created strong incentives for knowledge to flow to local implementers, but with little encouragement and few structures for the potentially valuable lessons from implementation to flow back to global best practice or research-based knowledge. The Global Fund could play an influential role in fostering much-needed learning from implementation. We suggest that three initial steps are required to start this process: acknowledging shared responsibility for learning across the knowledge system; analysing the Global Fund's existing data (and refining data collection over time); and supporting recipients and technical partners to invest resources in linking implementation with best practice and research. PMID:16917650

EAC training and medical support for International Space Station astronauts.

PubMed

Messerschmid, E; Haignere, J P; Damian, K; Damann, V

2000-11-01

The operation of the International Space Station (ISS) will be a global multilateral endeavour. Each International Partner will be responsible for the operation of its elements and for providing a crew complement proportional to its share of the overall resources. The preparations of the European Astronaut Centre to furnish training and medical support for the ISS astronauts are described.

Changes in cerebral blood flow and vasoreactivity in response to acetazolamide in patients with transient global amnesia

PubMed Central

Sakashita, Y.; Kanai, M.; Sugimoto, T.; Taki, S.; Takamori, M.

1997-01-01

OBJECTIVE—Previous reports about changes in cerebral blood flow (CBF) in transient global amnesia disclosed decreased flow in some parts of the brain. However, CBF analyses in most reports were qualitative but not quantitative. The purpose of this study was to determine changes in CBF in transient global amnesia.
METHODS—The CBF was measured and the vasoreactive response to acetazolamide was evaluated in six patients with transient global amnesia using technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPECT). The CBF was measured during an attack in two patients and soon after an attack in the other four. About one month later, CBF was re-evaluated in each patient.
RESULTS—Two patients examined during an attack and one patient examined five hours after an attack had increased blood flow in the occipital cortex and cerebellum. Three patients examined at six to 10 hours after an attack had decreased blood flow in the thalamus, cerebellum, or putamen. These abnormalities of blood flow almost disappeared in all patients one month after onset. The vasodilatory response to acetazolamide, which was evaluated initially using SPECT, was poor in areas of increased blood flow. By the second evaluation of CBF with acetazolamide, the vasodilatory response had returned to normal.
CONCLUSIONS—In a patient with transient global amnesia, CBF increased in the vertebrobasilar territory during the attack and decreased afterwards. The vasodilatory response to acetazolamide may be impaired in the parts of the brain with increased blood flow. It is suggested that transient global amnesia is distinct from migraine but may share the same underlying mechanism.

 PMID:9408101

Nutrition labelling: a review of research on consumer and industry response in the global South.

PubMed

Mandle, Jessie; Tugendhaft, Aviva; Michalow, Julia; Hofman, Karen

2015-01-01

To identify peer-reviewed research on consumers' usage and attitudes towards the nutrition label and the food industry's response to labelling regulations outside Europe, North America, and Australia and to determine knowledge gaps for future research. Narrative review. This review identified nutrition labelling research from 20 countries in Asia, Africa, the Middle East, and Latin America. Consumers prefer that pre-packaged food include nutrition information, although there is a disparity between rates of use and comprehension. Consumer preference is for front-of-pack labelling and for information that shows per serving or portion as a reference unit, and label formats with graphics or symbols. Research on the food and beverage industry's response is more limited but shows that industry plays an active role in influencing legislation and regulation. Consumers around the world share preferences with consumers in higher income countries with respect to labelling. However, this may reflect the research study populations, who are often better educated than the general population. Investigation is required into how nutrition labels are received in emerging economies especially among the urban and rural poor, in order to assess the effectiveness of labelling policies. Further research into the outlook of the food and beverage industry, and also on expanded labelling regulations is a priority. Sharing context-specific research regarding labelling between countries in the global South could be mutually beneficial in evaluating obesity prevention policies and strategies.

Towards Social Radiology as an Information Infrastructure: Reconciling the Local With the Global

PubMed Central

2014-01-01

The current widespread use of medical images and imaging procedures in clinical practice and patient diagnosis has brought about an increase in the demand for sharing medical imaging studies among health professionals in an easy and effective manner. This article reveals the existence of a polarization between the local and global demands for radiology practice. While there are no major barriers for sharing such studies, when access is made from a (local) picture archive and communication system (PACS) within the domain of a healthcare organization, there are a number of impediments for sharing studies among health professionals on a global scale. Social radiology as an information infrastructure involves the notion of a shared infrastructure as a public good, affording a social space where people, organizations and technical components may spontaneously form associations in order to share clinical information linked to patient care and radiology practice. This article shows however, that such polarization establishes a tension between local and global demands, which hinders the emergence of social radiology as an information infrastructure. Based on an analysis of the social space for radiology practice, the present article has observed that this tension persists due to the inertia of a locally installed base in radiology departments, for which common teleradiology models are not truly capable of reorganizing as a global social space for radiology practice. Reconciling the local with the global signifies integrating PACS and teleradiology into an evolving, secure, heterogeneous, shared, open information infrastructure where the conceptual boundaries between (local) PACS and (global) teleradiology are transparent, signaling the emergence of social radiology as an information infrastructure. PMID:25600710

Closing the Loop on Visa Security: A Case for Change

DTIC Science & Technology

2010-12-01

in order to accomplish a shared goal (Gerencser, Lee, Napolitano, & Kelly ). The literature leaves room for further research regarding what policies...Secretary of State for Consular Affairs Maura Harty described responsibilities that remain with the DOS: The Secretary of State will have...Van Lee, R., Napolitano, F. & Kelly , C. (2008). Megacommunities: How leaders of government, business and non-profits can tackle today ’s global

Allocating a 2 °C cumulative carbon budget to countries

NASA Astrophysics Data System (ADS)

Gignac, Renaud; Damon Matthews, H.

2015-07-01

Recent estimates of the global carbon budget, or allowable cumulative CO2 emissions consistent with a given level of climate warming, have the potential to inform climate mitigation policy discussions aimed at maintaining global temperatures below 2 °C. This raises difficult questions, however, about how best to share this carbon budget amongst nations in a way that both respects the need for a finite cap on total allowable emissions, and also addresses the fundamental disparities amongst nations with respect to their historical and potential future emissions. Here we show how the contraction and convergence (C&C) framework can be applied to the division of a global carbon budget among nations, in a manner that both maintains total emissions below a level consistent with 2 °C, and also adheres to the principle of attaining equal per capita CO2 emissions within the coming decades. We show further that historical differences in responsibility for climate warming can be quantified via a cumulative carbon debt (or credit), which represents the amount by which a given country’s historical emissions have exceeded (or fallen short of) the emissions that would have been consistent with their share of world population over time. This carbon debt/credit calculation enhances the potential utility of C&C, therefore providing a simple method to frame national climate mitigation targets in a way that both accounts for historical responsibility, and also respects the principle of international equity in determining future emissions allowances.

Lessons Learned and Global Partnerships: Stories of Sexual and Reproductive Health from Namibia

ERIC Educational Resources Information Center

Maurer, Lis; Kelly, Maureen

2005-01-01

Through a Global Partnership Project, Planned Parenthood of the Southern Finger Lakes in Ithaca, New York and the Namibian Planned Parenthood Association (NAPPA) in Windhoek, Namibia have joined together to share best practices, technical assistance, support, and resources. The Global Partners share the common goal of increasing awareness,…

National Culture in Practice: Its Impact on Knowledge Sharing in Global Virtual Collaboration

ERIC Educational Resources Information Center

Wei, Kangning

2009-01-01

Issues concerning global virtual collaboration have received considerable attention in both the academic and practical world; however, little research has been conducted on knowledge-sharing activities in global virtual collaboration, which is a key process to achieve collaboration effectiveness. Due to national culture having been seen as one of…

The core legion object model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, M.; Grimshaw, A.

1996-12-31

The Legion project at the University of Virginia is an architecture for designing and building system services that provide the illusion of a single virtual machine to users, a virtual machine that provides secure shared object and shared name spaces, application adjustable fault-tolerance, improved response time, and greater throughput. Legion targets wide area assemblies of workstations, supercomputers, and parallel supercomputers, Legion tackles problems not solved by existing workstation based parallel processing tools; the system will enable fault-tolerance, wide area parallel processing, inter-operability, heterogeneity, a single global name space, protection, security, efficient scheduling, and comprehensive resource management. This paper describes themore » core Legion object model, which specifies the composition and functionality of Legion`s core objects-those objects that cooperate to create, locate, manage, and remove objects in the Legion system. The object model facilitates a flexible extensible implementation, provides a single global name space, grants site autonomy to participating organizations, and scales to millions of sites and trillions of objects.« less

Tracing global supply chains to air pollution hotspots

NASA Astrophysics Data System (ADS)

Moran, Daniel; Kanemoto, Keiichiro

2016-09-01

While high-income countries have made significant strides since the 1970s in improving air quality, air pollution continues to rise in many developing countries and the world as a whole. A significant share of the pollution burden in developing countries can be attributed to production for export to consumers in high-income nations. However, it remains a challenge to quantify individual actors’ share of responsibility for pollution, and to involve parties other than primary emitters in cleanup efforts. Here we present a new spatially explicit modeling approach to link SO2, NO x , and PM10 severe emissions hotspots to final consumers via global supply chains. These maps show developed countries reducing their emissions domestically but driving new pollution hotspots in developing countries. This is also the first time a spatially explicit footprint inventory has been established. Linking consumers and supply chains to emissions hotspots creates opportunities for other parties to participate alongside primary emitters and local regulators in pollution abatement efforts.

Viewing benefit sharing in global health research through the lens of Aristotelian justice.

PubMed

Dauda, Bege; Dierickx, Kris

2017-06-01

The ethics of benefit sharing has been a topical issue in global health research in resource-limited countries. It pertains to the distribution of goods, benefits and advantages to the research participants, communities and countries that are involved in research. One of the nuances in benefit sharing is the ethical justification on which the concept should be based. Extensive literature outlining the different principles underlying benefit sharing is available. The purpose of this paper is to examine the proposed principles using Aristotelian principles of justice. The paper assesses the central idea of Aristotelian justice and applies and evaluates this idea to benefit sharing in research, especially when commercial research sponsors conduct research in resource-limited countries. Two categories of Aristotelian justice-universal and particular-were examined and their contribution to the benefit-sharing discourse assessed. On the one hand, benefit sharing in accordance with universal justice requires that for-profit research sponsors obey the legal regulations and international standards set for benefit sharing. On the other hand, benefit sharing in accordance with particular justice transcends obeying legal requirements and standards to a realm of acting in an ethically accepted manner. Accordingly, the paper further examines three perspectives of particular justice and develops ethical justification for benefit sharing in global health research. As Aristotelian justice is still relevant to the contemporary discourse on justice, this paper broadens the ethical justifications of benefit sharing in global health research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

78 FR 67427 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-12

... Change Proposing to Amend the Rule Governing the Listing and Trading of Shares of the WisdomTree Global... change to the means of achieving the investment objective applicable to the WisdomTree Global Real Return... Rule 8.600 \\4\\ (``Managed Fund Shares'').\\5\\ The Shares are offered by the WisdomTree Trust (``Trust...

77 FR 65237 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Granting Approval of Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-25

... Relating to the Listing and Trading of Shares of the WisdomTree Global Corporate Bond Fund of the WisdomTree Trust October 19, 2012. I. Introduction On August 15, 2012, The NASDAQ Stock Market LLC (``Nasdaq... proposed rule change to list and trade the shares (``Shares'') of the WisdomTree Global Corporate Bond Fund...

77 FR 9281 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-16

... and Trading of the PIMCO Global Advantage Inflation-Linked Bond Strategy Fund Under NYSE Arca Equities...''): PIMCO Global Advantage Inflation-Linked Bond Strategy Fund. The text of the proposed rule change is... Shares \\3\\ (``Shares'') under NYSE Arca Equities Rule 8.600: PIMCO Global Advantage Inflation-Linked Bond...

Determinants of Achieving Effective Shared Situational Awareness within the Context of Global Maritime Partnerships

DTIC Science & Technology

2013-06-01

and security, vessel traffic management, accident and disaster response, search and rescue as well as law enforcement are collecting information...piracy threat. Individually Nigeria , Ghana, Benin, Togo, Cameroon and Senegal have taken practical steps to police their waters but they lack...use their vast natural resources for socio-economic development of their countries. Lloyd’s, the leading maritime insurer, has listed Nigeria , Benin

Noise effects on the health status in a dynamic failure model for living organisms

NASA Astrophysics Data System (ADS)

Kang, H.; Jo, J.; Choi, M. Y.; Choi, J.; Yoon, B.-G.

2007-03-01

We study internal and external noise effects on the healthy-unhealthy transition and related phenomena in a dynamic failure model for living organisms. It is found that internal noise makes the system weaker, leading to breakdown under smaller stress. The discontinuous healthy-unhealthy transition in a system with global load sharing below a critical point is naturally explained in terms of the bistability for the health status. External noise present in constant stress gives similar results; further, it induces resonance in response to periodic stress, regardless of load transfer. In the case of local load sharing, such periodic stress is revealed more hazardous than the constant stress.

Promoting global health: utilizing WHO to integrate public health, innovation and intellectual property.

PubMed

Mackey, Tim K; Liang, Bryan A

2012-12-01

The appropriate role of innovation and intellectual property (IP) in global public health is a controversial issue. Discussion is one-sided, with potential benefits advocated by industry in stark contrast to condemnation by certain civil society players. WHO's Public Health, Innovation and Intellectual Property Department (PHI) was established to address healthcare resource need for developing countries, assess impact of innovation and IP on access to medicines, explore innovative funding mechanisms for R&D and provide evidence-based policy-making recommendations in response to the changing global health landscape. Importantly, PHI could represent a potential forum to bridge shared, yet often diverse, interests and opportunities between various public and private stakeholders, a crucial issue for ensuring the future viability of WHO. Copyright © 2012 Elsevier Ltd. All rights reserved.

Nutrition labelling: a review of research on consumer and industry response in the global South

PubMed Central

Mandle, Jessie; Tugendhaft, Aviva; Michalow, Julia; Hofman, Karen

2015-01-01

Background To identify peer-reviewed research on consumers’ usage and attitudes towards the nutrition label and the food industry's response to labelling regulations outside Europe, North America, and Australia and to determine knowledge gaps for future research. Design Narrative review. Results This review identified nutrition labelling research from 20 countries in Asia, Africa, the Middle East, and Latin America. Consumers prefer that pre-packaged food include nutrition information, although there is a disparity between rates of use and comprehension. Consumer preference is for front-of-pack labelling and for information that shows per serving or portion as a reference unit, and label formats with graphics or symbols. Research on the food and beverage industry's response is more limited but shows that industry plays an active role in influencing legislation and regulation. Conclusions Consumers around the world share preferences with consumers in higher income countries with respect to labelling. However, this may reflect the research study populations, who are often better educated than the general population. Investigation is required into how nutrition labels are received in emerging economies especially among the urban and rural poor, in order to assess the effectiveness of labelling policies. Further research into the outlook of the food and beverage industry, and also on expanded labelling regulations is a priority. Sharing context-specific research regarding labelling between countries in the global South could be mutually beneficial in evaluating obesity prevention policies and strategies. PMID:25623608

Impacts of climate change on the global forest sector

USGS Publications Warehouse

Perez-Garcia, J.; Joyce, L.A.; McGuire, A.D.; Xiao, X.

2002-01-01

The path and magnitude of future anthropogenic emissions of carbon dioxide will likely influence changes in climate that may impact the global forest sector. These responses in the global forest sector may have implications for international efforts to stabilize the atmospheric concentration of carbon dioxide. This study takes a step toward including the role of global forest sector in integrated assessments of the global carbon cycle by linking global models of climate dynamics, ecosystem processes and forest economics to assess the potential responses of the global forest sector to different levels of greenhouse gas emissions. We utilize three climate scenarios and two economic scenarios to represent a range of greenhouse gas emissions and economic behavior. At the end of the analysis period (2040), the potential responses in regional forest growing stock simulated by the global ecosystem model range from decreases and increases for the low emissions climate scenario to increases in all regions for the high emissions climate scenario. The changes in vegetation are used to adjust timber supply in the softwood and hardwood sectors of the economic model. In general, the global changes in welfare are positive, but small across all scenarios. At the regional level, the changes in welfare can be large and either negative or positive. Markets and trade in forest products play important roles in whether a region realizes any gains associated with climate change. In general, regions with the lowest wood fiber production cost are able to expand harvests. Trade in forest products leads to lower prices elsewhere. The low-cost regions expand market shares and force higher-cost regions to decrease their harvests. Trade produces different economic gains and losses across the globe even though, globally, economic welfare increases. The results of this study indicate that assumptions within alternative climate scenarios and about trade in forest products are important factors that strongly influence the effects of climate change on the global forest sector.

High altitude environmental monitoring: the SHARE project and CEOP-HE

NASA Astrophysics Data System (ADS)

Tartari, G.

2009-04-01

Mountain areas above 2,500 m a.s.l. constitute about 25% of the Earth's surface and play a fundamental role in the global water balance, while influencing global climate and atmospheric circulation systems. Several millions, including lowlanders, are directly affected by the impacts of climate change on glaciers and water resource distribution. Mountains and high altitude plateaus are subject to the highest rate of temperature increase (e.g., Tibetan Plateau) and are recognized as particularly vulnerable to the effects of climate change. In spite of this, the number of permanent monitoring sites in the major environmental networks decreases with altitude. On a sample of two hundred high altitude automatic weather stations located above 2,500 m a.s.l., less than 20% are over 4,000 m, while there are only 24 stations in the world that could be considered "complete" high altitude observatories. Furthermore, entire mountain areas are left uncovered, creating significant data gaps which make reliable modelling and forecasting nearly impossible. In response to these problems, Ev-K2-CNR has developed the project SHARE (Stations at High Altitude for Research on the Environment) with the support of the Italian government and in collaboration with UNEP. This integrated environmental monitoring and research project aims to improve knowledge on the local, regional and global consequences of climate change in mountain regions and on the influence of high elevations on climate, atmospheric circulation and hydrology. SHARE today boasts a network of 13 permanent monitoring stations between 2,165 m and 8,000 m. Affiliated researchers have produced over 150 scientific publications in atmospheric sciences, meteorology and climate, glaciology, limnology and paleolimnology and geophysics. SHARE network data is also contributed to international programs (UNEP-ABC, WMO-GAW, WCRP-GEWEX-CEOP, NASA-AERONET, ILTER, EU-EUSAAR, EU-ACCENT). Within this context, the CEOP-High Elevations (CEOP-HE) element of regional focus was developed under the GEWEX CEOP programme to study multi-scale variability in water and energy cycles in high elevation areas, and to help improve observations, modelling and data management. Future plans include expansion of the SHARE network, addition of other key research areas including hydrology, and creation of mechanisms to favour exchange of data amongst high altitude networks. In coordination with other global research and monitoring projects (CliC, etc.), SHARE and CEOP-HE could provide a more organic and well-distributed interdisciplinary network, thus allowing governments and international agencies to better face impacts of climate change effects on energy and water budgets and elaborate appropriate adaptation strategies.

The global position of the U S forest products industry

Treesearch

Jeffrey P. Prestemon; David N. Wear; Michaela O. Foster

2015-01-01

The United States’ share of global industrial roundwood production has declined since the 1990s. We reviewed data from 1961-2013 to evaluate the extent of this decline for industrial roundwood and derived secondary forest products compared to other major producing countries. We find that the U.S. global share of industrial roundwood peaked at 28 percent in 1999 but...

Understanding global health governance as a complex adaptive system.

PubMed

Hill, Peter S

2011-01-01

The transition from international to global health reflects the rapid growth in the numbers and nature of stakeholders in health, as well as the constant change embodied in the process of globalisation itself. This paper argues that global health governance shares the characteristics of complex adaptive systems, with its multiple and diverse players, and their polyvalent and constantly evolving relationships, and rich and dynamic interactions. The sheer quantum of initiatives, the multiple networks through which stakeholders (re)configure their influence, the range of contexts in which development for health is played out - all compound the complexity of this system. This paper maps out the characteristics of complex adaptive systems as they apply to global health governance, linking them to developments in the past two decades, and the multiple responses to these changes. Examining global health governance through the frame of complexity theory offers insight into the current dynamics of governance, and while providing a framework for making meaning of the whole, opens up ways of accessing this complexity through local points of engagement.

Overseas Basing of U.S. Military Forces: An Assessment of Relative Costs and Strategic Benefits

DTIC Science & Technology

2013-01-01

LCDR Mike Williams, CDR Matt Konopka, Gregg Nishimura, MG James Boozer, COL Andrew Heppelmann, LTC Robert Murphy, MAJ Garrett Trott , MAJ Thomas...2012 Defense Strategic Guidance calls for evolution and innovation in overseas posture. It sets forth significant guidance for posture planning as...also remains important for sharing the costs and responsibilities of global leadership.… Whenever possible, we will develop innovative , low-cost, and

Global bioethics and communitarianism.

PubMed

ten Have, Henk A M J

2011-10-01

This paper explores the role of 'community' in the context of global bioethics. With the present globalization of bioethics, new and interesting references are made to this concept. Some are familiar, for example, community consent. This article argues that the principle of informed consent is too individual-oriented and that in other cultures, consent can be community-based. Other references to 'community' are related to the novel principle of benefit sharing in the context of bioprospecting. The application of this principle necessarily requires the identification and construction of communities. On the global level there are also new uses of the concept of community as 'global community.' Three uses are distinguished: (1) a diachronic use, including past, present, and future generations, (2) a synchronic ecological use, including nonhuman species, and (3) a synchronic planetary use, including all human beings worldwide. Although there is a tension between the communitarian perspective and the idea of global community, this article argues that the third use can broaden communitarianism. The current development towards cosmopolitanism is creating a new global community that represents humanity as a whole, enabling identification of world citizens and evoking a sense of global solidarity and responsibility. The emergence of global bioethics today demonstrates this development.

Global Mental Health: sharing and synthesizing knowledge for sustainable development.

PubMed

O'Donnell, K; O'Donnell, M Lewis

2016-01-01

Global mental health (GMH) is a growing domain with an increasing capacity to positively impact the world community's efforts for sustainable development and wellbeing. Sharing and synthesizing GMH and multi-sectoral knowledge, the focus of this paper, is an important way to support these global efforts. This paper consolidates some of the most recent and relevant 'context resources' [global multi-sector (GMS) materials, emphasizing world reports on major issues] and 'core resources' (GMH materials, including newsletters, texts, conferences, training, etc.). In addition to offering a guided index of materials, it presents an orientation framework (global integration) to help make important information as accessible and useful as possible. Mental health colleagues are encouraged to stay current in GMH and global issues, to engage in the emerging agendas for sustainable development and wellbeing, and to intentionally connect and contribute across sectors. Colleagues in all sectors are encouraged to do likewise, and to take advantage of the wealth of shared and synthesized knowledge in the GMH domain, such as the materials featured in this paper.

US forest products in the global economy

Treesearch

Dave N Wear; Jeff Prestemon; Michaela O. Foster

2015-01-01

The United States’ shares of global industrial roundwood production and derivative products have declined precipitously since the 1990s. We evaluate the extent of these declines compared with those of major producing countries from 1961 to 2013. We find that the US global share of industrial roundwood peaked at 28% in 1999 but by 2013 was at 17%, with the decline...

Building Intercultural Understandings through Global Literature

ERIC Educational Resources Information Center

Martens, Prisca; Martens, Ray; Doyle, Michelle Hassay; Loomis, Jenna; Fuhrman, Laura; Furnari, Christie; Soper, Elizabeth; Stout, Robbie

2015-01-01

In this article the authors share how they use global literature picturebooks with pre-kindergarten, kindergarten, and first grade children in the context of A Curriculum That is International to develop the children's intercultural understandings. The picturebooks, shared through read alouds, individual and partner reading, and browsing, is…

Global Practices of Interprofessional Education (IPE) and Relevant International Activities.

PubMed

Arakawa, Naoko

2017-01-01

Activities related to interprofessional education (IPE) vary between countries according to local and national health needs and systems. The International Pharmaceutical Federation (FIP) Education Initiative endeavors to provide a global vision in IPE by the sharing of experiences and gathering of evidence collaboratively to facilitate country-level initiatives. The purpose of this paper is to contribute to the further development of IPE activities in pharmacy in Japan through sharing global perspectives and activities related to IPE. FIP Education Initiative published the Interprofessional Education in a Pharmacy Context: Global Report in September 2015, which marked a milestone in the growing recognition of IPE in pharmacy globally. The paper shared global and regional perspectives and experiences in IPE in pharmacy, both from the report and FIP activities. This paper can be seen as a snapshot of IPE-related international activities, which enables gaps and challenges in implementing IPE activities in Japan to be identified. This paper provides an opportunity to explore global trends and initiatives regarding IPE, and to consider how to form and implement IPE specifically based on Japanese health needs and systems.

Optimal global value of information trials: better aligning manufacturer and decision maker interests and enabling feasible risk sharing.

PubMed

Eckermann, Simon; Willan, Andrew R

2013-05-01

Risk sharing arrangements relate to adjusting payments for new health technologies given evidence of their performance over time. Such arrangements rely on prospective information regarding the incremental net benefit of the new technology, and its use in practice. However, once the new technology has been adopted in a particular jurisdiction, randomized clinical trials within that jurisdiction are likely to be infeasible and unethical in the cases where they would be most helpful, i.e. with current evidence of positive while uncertain incremental health and net monetary benefit. Informed patients in these cases would likely be reluctant to participate in a trial, preferring instead to receive the new technology with certainty. Consequently, informing risk sharing arrangements within a jurisdiction is problematic given the infeasibility of collecting prospective trial data. To overcome such problems, we demonstrate that global trials facilitate trialling post adoption, leading to more complete and robust risk sharing arrangements that mitigate the impact of costs of reversal on expected value of information in jurisdictions who adopt while a global trial is undertaken. More generally, optimally designed global trials offer distinct advantages over locally optimal solutions for decision makers and manufacturers alike: avoiding opportunity costs of delay in jurisdictions that adopt; overcoming barriers to evidence collection; and improving levels of expected implementation. Further, the greater strength and translatability of evidence across jurisdictions inherent in optimal global trial design reduces barriers to translation across jurisdictions characteristic of local trials. Consequently, efficiently designed global trials better align the interests of decision makers and manufacturers, increasing the feasibility of risk sharing and the expected strength of evidence over local trials, up until the point that current evidence is globally sufficient.

Shared language:Towards more effective communication.

PubMed

Thomas, Joyce; McDonagh, Deana

2013-01-01

The ability to communicate to others and express ourselves is a basic human need. As we develop our understanding of the world, based on our upbringing, education and so on, our perspective and the way we communicate can differ from those around us. Engaging and interacting with others is a critical part of healthy living. It is the responsibility of the individual to ensure that they are understood in the way they intended.Shared language refers to people developing understanding amongst themselves based on language (e.g. spoken, text) to help them communicate more effectively. The key to understanding language is to first notice and be mindful of your language. Developing a shared language is an ongoing process that requires intention and time, which results in better understanding.Shared language is critical to collaboration, and collaboration is critical to business and education. With whom and how many people do you connect? Your 'shared language' makes a difference in the world. So, how do we successfully do this? This paper shares several strategies.Your sphere of influence will carry forward what and how you are communicating. Developing and nurturing a shared language is an essential element to enhance communication and collaboration whether it is simply between partners or across the larger community of business and customers. Constant awareness and education is required to maintain the shared language. We are living in an increasingly smaller global community. Business is built on relationships. If you invest in developing shared language, your relationships and your business will thrive.

Global Governance Mechanisms to Address Antimicrobial Resistance.

PubMed

Padiyara, Ponnu; Inoue, Hajime; Sprenger, Marc

2018-01-01

Since their discovery, antibiotics, and more broadly, antimicrobials, have been a cornerstone of modern medicine. But the overuse and misuse of these drugs have led to rising rates of antimicrobial resistance, which occurs when bacteria adapt in ways that render antibiotics ineffective. A world without effective antibiotics can have drastic impacts on population health, global development, and the global economy. As a global common good, antibiotic effectiveness is vulnerable to the tragedy of the commons, where a shared limited resource is overused by a community when each individual exploits the finite resource for their own benefit. A borderless threat like antimicrobial resistance requires global governance mechanisms to mitigate its emergence and spread, and it is the responsibility of all countries and relevant multilateral organizations. These mechanisms can be in the form of legally binding global governance mechanisms such as treaties and regulatory standards or nonbinding mechanisms such as political declarations, resolutions, or guidelines. In this article, we argue that while both are effective methods, the strong, swift, and coordinated action needed to address rising rates of antimicrobial resistance will be better served through legally binding governance mechanisms.

Early differential sensitivity of evoked-potentials to local and global shape during the perception of three-dimensional objects.

PubMed

Leek, E Charles; Roberts, Mark; Oliver, Zoe J; Cristino, Filipe; Pegna, Alan J

2016-08-01

Here we investigated the time course underlying differential processing of local and global shape information during the perception of complex three-dimensional (3D) objects. Observers made shape matching judgments about pairs of sequentially presented multi-part novel objects. Event-related potentials (ERPs) were used to measure perceptual sensitivity to 3D shape differences in terms of local part structure and global shape configuration - based on predictions derived from hierarchical structural description models of object recognition. There were three types of different object trials in which stimulus pairs (1) shared local parts but differed in global shape configuration; (2) contained different local parts but shared global configuration or (3) shared neither local parts nor global configuration. Analyses of the ERP data showed differential amplitude modulation as a function of shape similarity as early as the N1 component between 146-215ms post-stimulus onset. These negative amplitude deflections were more similar between objects sharing global shape configuration than local part structure. Differentiation among all stimulus types was reflected in N2 amplitude modulations between 276-330ms. sLORETA inverse solutions showed stronger involvement of left occipitotemporal areas during the N1 for object discrimination weighted towards local part structure. The results suggest that the perception of 3D object shape involves parallel processing of information at local and global scales. This processing is characterised by relatively slow derivation of 'fine-grained' local shape structure, and fast derivation of 'coarse-grained' global shape configuration. We propose that the rapid early derivation of global shape attributes underlies the observed patterns of N1 amplitude modulations. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

NASA's Support to Flood Response

NASA Astrophysics Data System (ADS)

Green, D. S.; Murray, J. J.; Stough, T.

2016-12-01

The extent of flood and inundation, the impacts on people and infrastructure, and generally the situational awareness on all scales for decision making are areas where NASA is mobilizing scientific results, advanced sensing and technologies, experts and partnerships to support response. NASA has targeted mature application science and ready technology for flood and inundation monitoring and assessment. This includes supporting timely data management and product dissemination with users and partners. Requirements are captured in the form of science-area questions, while solutions measure readiness for use by considering standard tools and approaches that make information more accessible, interoperable, understandable and reliable. The program collaborates with capacity building and areas of education and outreach needed to create and leverage non-traditional partnerships in transdisciplinary areas including socio-economic practice, preparedness and resilience assessment, early warning and forecast response, and emergency management, relief and recovery. The program outcomes also seek alignment with and support to global and community priorities related to water resources and food security. This presentation will examine the achievements of individual projects and the challenges and opportunities of more comprehensive and collaborative teams behind NASA's response to global flooding. Examples from recent event mobilization will be reviewed including to the serious of domestic floods across the south and Midwest United States throughout 2015 and 2016. Progress on the combined use of optical, microwave and SAR remote sensing measurements, topographic and geodetic data and mapping, data sharing practices will be reviewed. Other response case studies will examine global flood events monitored, characterized and supported in various boundary regions and nations. Achievements and future plans will be described for capabilities including global flood modeling, near real time flood water mapping and damage mapping, observatories, missions and tools to assess surface water variability. Progress being made to establish a comprehensive global flood science team and coordinated response system will be highlighted.

Who is in control of road safety? A STAMP control structure analysis of the road transport system in Queensland, Australia.

PubMed

Salmon, Paul M; Read, Gemma J M; Stevens, Nicholas J

2016-11-01

Despite significant progress, road trauma continues to represent a global safety issue. In Queensland (Qld), Australia, there is currently a focus on preventing the 'fatal five' behaviours underpinning road trauma (drug and drink driving, distraction, seat belt wearing, speeding, and fatigue), along with an emphasis on a shared responsibility for road safety that spans road users, vehicle manufacturers, designers, policy makers etc. The aim of this article is to clarify who shares the responsibility for road safety in Qld and to determine what control measures are enacted to prevent the fatal five behaviours. This is achieved through the presentation of a control structure model that depicts the actors and organisations within the Qld road transport system along with the control and feedback relationships that exist between them. Validated through a Delphi study, the model shows a diverse set of actors and organisations who share the responsibility for road safety that goes beyond those discussed in road safety policies and strategies. The analysis also shows that, compared to other safety critical domains, there are less formal control structures in road transport and that opportunities exist to add new controls and strengthen existing ones. Relationships that influence rather than control are also prominent. Finally, when compared to other safety critical domains, the strength of road safety controls is brought into question. Copyright © 2016 Elsevier Ltd. All rights reserved.

Ethics in practice: the state of the debate on promoting the social value of global health research in resource poor settings particularly Africa.

PubMed

Lairumbi, Geoffrey M; Michael, Parker; Fitzpatrick, Raymond; English, Michael C

2011-11-15

Promoting the social value of global health research undertaken in resource poor settings has become a key concern in global research ethics. The consideration for benefit sharing, which concerns the elucidation of what if anything, is owed to participants, their communities and host nations that take part in such research, and the obligations of researchers involved, is one of the main strategies used for promoting social value of research. In the last decade however, there has been intense debate within academic bioethics literature seeking to define the benefits, the beneficiaries, and the scope of obligations for providing these benefits. Although this debate may be indicative of willingness at the international level to engage with the responsibilities of researchers involved in global health research, it remains unclear which forms of benefits or beneficiaries should be considered. International and local research ethics guidelines are reviewed here to delineate the guidance they provide. We reviewed documents selected from the international compilation of research ethics guidelines by the Office for Human Research Protections under the US Department of Health and Human Services. Access to interventions being researched, the provision of unavailable health care, capacity building for individuals and institutions, support to health care systems and access to medical and public health interventions proven effective, are the commonly recommended forms of benefits. The beneficiaries are volunteers, disease or illness affected communities and the population in general. Interestingly however, there is a divide between "global opinion" and the views of particular countries within resource poor settings as made explicit by differences in emphasis regarding the potential benefits and the beneficiaries. Although in theory benefit sharing is widely accepted as one of the means for promoting the social value of international collaborative health research, there is less agreement amongst major guidelines on the specific responsibilities of researchers over what is ethical in promoting the social value of research. Lack of consensus might have practical implications for efforts aimed at enhancing the social value of global health research undertaken in resource poor settings. Further developments in global research ethics require more reflection, paying attention to the practical realities of implementing the ethical principles in real world context. © 2011 Lairumbi et al; licensee BioMed Central Ltd.

Global governance and the broader determinants of health: A comparative case study of UNDP's and WTO's engagement with global health.

PubMed

Gopinathan, Unni; Watts, Nick; Lefebvre, Alexandre; Cheung, Arthur; Hoffman, Steven J; Røttingen, John-Arne

2018-05-31

This comparative case study investigated how two intergovernmental organisations without formal health mandates - the United Nations Development Programme (UNDP) and the World Trade Organization (WTO) - have engaged with global health issues. Triangulating insights from key institutional documents, ten semi-structured interviews with senior officials, and scholarly books tracing the history of both organisations, the study identified an evolving and broadened engagement with global health issues in UNDP and WTO. Within WTO, the dominant view was that enhancing international trade is instrumental to improving global health, although the need to resolve tensions between public health objectives and WTO agreements was recognised. For UNDP, interviewees reported that the agency gained prominence in global health for its response to HIV/AIDS in the 1990s and early 2000s. Learning from that experience, the agency has evolved and expanded its role in two respects: it has increasingly facilitated processes to provide global normative direction for global health issues such as HIV/AIDS and access to medicines, and it has expanded its focus beyond HIV/AIDS. Overall, the study findings suggest the need for seeking greater integration among international institutions, closing key global institutional gaps, and establishing a shared global institutional space for promoting action on the broader determinants of health.

Enhancing and Transforming Global Learning Communities with Augmented Reality

ERIC Educational Resources Information Center

Frydenberg, Mark; Andone, Diana

2018-01-01

Augmented and virtual reality applications bring new insights to real world objects and scenarios. This paper shares research results of the TalkTech project, an ongoing study investigating the impact of learning about new technologies as members of global communities. This study shares results of a collaborative learning project about augmented…

78 FR 78256 - Shared Responsibility Payment for Not Maintaining Minimum Essential Coverage; Correction

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2013-12-26

... Shared Responsibility Payment for Not Maintaining Minimum Essential Coverage; Correction AGENCY: Internal... 5000A of the Internal Revenue Code for the shared responsibility payment for not maintaining minimum... language ``for shared responsibility payment for an'' is corrected to read ``for the shared responsibility...

Stories from OpenAQ, a Global and Grassroots Open Air Quality Community

NASA Astrophysics Data System (ADS)

Hasenkopf, C. A.; Flasher, J. C.; Veerman, O.; Scalamogna, A.; Silva, D.; Salmon, M.; Buuralda, D.; DeWitt, L. H.

2016-12-01

Air pollution, responsible for more deaths each year than HIV/AIDS and malaria, combined, is a global public health crisis. Yet many scientific questions, including those directly relevant for policy, remain unanswered when it comes to the impact of air pollution on health in highly polluted environments. Often, specific solutions to improving air quality are local and sustained through public engagement, policy and monitoring. Both the overarching science of air quality and health and local solutions rely on access to reliable, timely air quality data. Over the past year, the OpenAQ community has opened up existing disparate air quality data in 24 countries through an open source platform (openaq.org) so that communities around the world can use it to advance science, public engagement, and policy. We will share stories of communities, from Delhi to Ulaanbaatar and from scientists to journalists, using open air quality data from our platform to advance their fight against air inequality. We will share recent research we have conducted on best practices for engaging different communities and building tools that enable the public to fully unleash the power of open air quality data to fight air inequality. The subsequent open-source tools (github.com/openaq) we have developed from this research and our entire data-sharing platform may be of interest to other open data communities.

Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds.

PubMed

Yung, Pui Yi; Grasso, Letizia Lo; Mohidin, Abeed Fatima; Acerbi, Enzo; Hinks, Jamie; Seviour, Thomas; Marsili, Enrico; Lauro, Federico M

2016-01-28

Volatile organic compounds (VOCs) are commonly used as solvents in various industrial settings. Many of them present a challenge to receiving environments, due to their toxicity and low bioavailability for degradation. Microorganisms are capable of sensing and responding to their surroundings and this makes them ideal detectors for toxic compounds. This study investigates the global transcriptomic responses of Escherichia coli K-12 to selected VOCs at sub-toxic levels. Cells grown in the presence of VOCs were harvested during exponential growth, followed by whole transcriptome shotgun sequencing (RNAseq). The analysis of the data revealed both shared and unique genetic responses compared to cells without exposure to VOCs. Results suggest that various functional gene categories, for example, those relating to Fe/S cluster biogenesis, oxidative stress responses and transport proteins, are responsive to selected VOCs in E. coli. The differential expression (DE) of genes was validated using GFP-promoter fusion assays. A variety of genes were differentially expressed even at non-inhibitory concentrations and when the cells are at their balanced-growth. Some of these genes belong to generic stress response and others could be specific to VOCs. Such candidate genes and their regulatory elements could be used as the basis for designing biosensors for selected VOCs.

Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds

PubMed Central

Yung, Pui Yi; Grasso, Letizia Lo; Mohidin, Abeed Fatima; Acerbi, Enzo; Hinks, Jamie; Seviour, Thomas; Marsili, Enrico; Lauro, Federico M.

2016-01-01

Volatile organic compounds (VOCs) are commonly used as solvents in various industrial settings. Many of them present a challenge to receiving environments, due to their toxicity and low bioavailability for degradation. Microorganisms are capable of sensing and responding to their surroundings and this makes them ideal detectors for toxic compounds. This study investigates the global transcriptomic responses of Escherichia coli K-12 to selected VOCs at sub-toxic levels. Cells grown in the presence of VOCs were harvested during exponential growth, followed by whole transcriptome shotgun sequencing (RNAseq). The analysis of the data revealed both shared and unique genetic responses compared to cells without exposure to VOCs. Results suggest that various functional gene categories, for example, those relating to Fe/S cluster biogenesis, oxidative stress responses and transport proteins, are responsive to selected VOCs in E. coli. The differential expression (DE) of genes was validated using GFP-promoter fusion assays. A variety of genes were differentially expressed even at non-inhibitory concentrations and when the cells are at their balanced-growth. Some of these genes belong to generic stress response and others could be specific to VOCs. Such candidate genes and their regulatory elements could be used as the basis for designing biosensors for selected VOCs. PMID:26818886

Leveraging the power of partnerships: spreading the vision for a population health care delivery model in western Kenya.

PubMed

Mercer, Tim; Gardner, Adrian; Andama, Benjamin; Chesoli, Cleophas; Christoffersen-Deb, Astrid; Dick, Jonathan; Einterz, Robert; Gray, Nick; Kimaiyo, Sylvester; Kamano, Jemima; Maritim, Beryl; Morehead, Kirk; Pastakia, Sonak; Ruhl, Laura; Songok, Julia; Laktabai, Jeremiah

2018-05-08

The Academic Model Providing Access to Healthcare (AMPATH) has been a model academic partnership in global health for nearly three decades, leveraging the power of a public-sector academic medical center and the tripartite academic mission - service, education, and research - to the challenges of delivering health care in a low-income setting. Drawing our mandate from the health needs of the population, we have scaled up service delivery for HIV care, and over the last decade, expanded our focus on non-communicable chronic diseases, health system strengthening, and population health more broadly. Success of such a transformative endeavor requires new partnerships, as well as a unification of vision and alignment of strategy among all partners involved. Leveraging the Power of Partnerships and Spreading the Vision for Population Health. We describe how AMPATH built on its collective experience as an academic partnership to support the public-sector health care system, with a major focus on scaling up HIV care in western Kenya, to a system poised to take responsibility for the health of an entire population. We highlight global trends and local contextual factors that led to the genesis of this new vision, and then describe the key tenets of AMPATH's population health care delivery model: comprehensive, integrated, community-centered, and financially sustainable with a path to universal health coverage. Finally, we share how AMPATH partnered with strategic planning and change management experts from the private sector to use a novel approach called a 'Learning Map®' to collaboratively develop and share a vision of population health, and achieve strategic alignment with key stakeholders at all levels of the public-sector health system in western Kenya. We describe how AMPATH has leveraged the power of partnerships to move beyond the traditional disease-specific silos in global health to a model focused on health systems strengthening and population health. Furthermore, we highlight a novel, collaborative tool to communicate our vision and achieve strategic alignment among stakeholders at all levels of the health system. We hope this paper can serve as a roadmap for other global health partners to develop and share transformative visions for improving population health globally.

Sharing Data to Build a Medical Information Commons: From Bermuda to the Global Alliance.

PubMed

Cook-Deegan, Robert; Ankeny, Rachel A; Maxson Jones, Kathryn

2017-08-31

The Human Genome Project modeled its open science ethos on nematode biology, most famously through daily release of DNA sequence data based on the 1996 Bermuda Principles. That open science philosophy persists, but daily, unfettered release of data has had to adapt to constraints occasioned by the use of data from individual people, broader use of data not only by scientists but also by clinicians and individuals, the global reach of genomic applications and diverse national privacy and research ethics laws, and the rising prominence of a diverse commercial genomics sector. The Global Alliance for Genomics and Health was established to enable the data sharing that is essential for making meaning of genomic variation. Data-sharing policies and practices will continue to evolve as researchers, health professionals, and individuals strive to construct a global medical and scientific information commons.

[Confidentiality as ethical responsibility and legal duty].

PubMed

Arroyo Cordero, Tamara

2009-01-01

The article analyzes the challenge that the health professionals encounter when trying to protect their patient's confidentiality, considering the increasing demand for globalization of the information. It discusses the importance that confidentiality has for the therapeutic alliance and how the government has protected it throughout time. It identifies weak areas in the protection of confidentiality, especially in the psychiatry field. Finally, it invites the reader to consider the real benefits of sharing patient's information when deciding whether to brake or not the patient's confidentiality.

A rare de novo interstitial duplication of 15q15.3q21.2 in a boy with severe short stature, hypogonadism, global developmental delay and intellectual disability.

PubMed

Yuan, Haiming; Meng, Zhe; Zhang, Lina; Luo, Xiangyang; Liu, Liping; Chen, Mengfan; Li, Xinwei; Zhao, Weiwei; Liang, Liyang

2016-01-01

Interstitial duplications distal to 15q13 are very rare. Here, we reported a 14-year-old boy with severe short stature, delayed bone age, hypogonadism, global developmental delay and intellectual disability. His had distinctive facial features including macrocephaly, broad forehead, deep-set and widely spaced eyes, broad nose bridge, shallow philtrum and thick lips. A de novo 6.4 Mb interstitial duplication of 15q15.3q21.2 was detected by chromosomal microarray analysis. We compared our patient's clinical phenotypes with those of several individuals with overlapping duplications and several candidate genes responsible for the phenotypes were identified as well. The results suggest a novel contiguous gene duplication syndrome characterized with shared features including short stature, hypogonadism, global developmental delay and other congenital anomalies.

Public health impacts of climate change in Nepal.

PubMed

Joshi, H D; Dhimal, B; Dhimal, M; Bhusal, C L

2011-04-01

Climate change is a global issue in this century which has challenged the survival of living creatures affecting the life supporting systems of the earth: atmosphere, hydrosphere and lithosphere. Scientists have reached in a consensus that climate change is happening. The anthropogenic emission of greenhouse gases is responsible for global warming and therefore climate change. Climate change may directly or indirectly affect human health through a range of pathways related to temperature and precipitation. The aim of this article is to share knowledge on how climate change can affect public health in Nepal based on scientific evidence from global studies and experience gained locally. In this review attempt has been made to critically analyze the scientific studies as well as policy documents of Nepalese Government and shed light on public health impact of climate change in the context of Nepal. Detailed scientific study is recommended to discern impact of climate change on public health problems in Nepal.

Evidence-based medicine and the governance of pandemic influenza.

PubMed

Kamradt-Scott, Adam

2012-01-01

The conventional response of governments to protect their populations against the threat of influenza has been to ensure adequate vaccine production and/or access to supplies of vaccines and antiviral medications. This focus has, in turn, shaped the global governance structures around pandemic influenza, with collective efforts centred on facilitating virus sharing, maintaining and increasing vaccine production, and ensuring access to pharmaceuticals - responses that remain unattainable for many low- and middle-income countries (LMICs) in the short to medium term. This paper argues that this emphasis on pharmacological responses reflects a particular view of biomedicine that pays inadequate attention to the weak capacity of many health systems. In more recent years, this dynamic has been further exacerbated by the influence of evidence-based medicine (EBM) that preferences certain types of biomedical knowledge and practice. This paper explores the role that EBM has played in shaping the global governance of pandemic influenza, and how it has served to reinforce and reify the authority of particular groups of actors, including policy-makers, elected officials and the medical community. The paper concludes that only by unpacking these structures and revealing the political authority in play can alternative policy responses more appropriate to LMICs be considered.

Preparing Global-Ready Teachers

ERIC Educational Resources Information Center

Larson, Lotta; Brown, Jennifer S.

2017-01-01

To produce global-ready students who can thrive and compete in an interconnected world, we must prepare global-ready teachers. This article shares how one teacher preparation program focuses on literacy, technology, and globalization, while offering relevant K-12 applications.

76 FR 13226 - Meeting of the Department of Justice Global Justice Information Sharing Initiative Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-10

... . DATES: The meeting will take place on Wednesday, April 20, 2011, from 8:30 a.m. to 4 p.m. ET. ADDRESSES: The meeting will take place at the Embassy Suites Washington, DC--Convention Center Hotel, 900 Tenth... priorities. The GAC will guide and monitor the development of the Global information sharing concept. It will...

Renewing governance.

PubMed

Loos, Gregory P

2003-01-01

Globalization's profound influence on social and political institutions need not be negative. Critics of globalization have often referred to the "Impossible Trinity" because decision-making must 1. respect national sovereignty, 2. develop and implement firm regulation, and 3. allow capital markets to be as free as possible. To many, such goals are mutually exclusive because history conditions us to view policy-making and governance in traditional molds. Thus, transnational governance merely appears impossible because current forms of governance were not designed to provide it. The world needs new tools for governing, and its citizens must seize the opportunity to help develop them. The rise of a global society requires a greater level of generality and inclusion than is found in most policy bodies today. Politicians need to re-examine key assumptions about government. States must develop ways to discharge their regulatory responsibilities across borders and collaborate with neighboring jurisdictions, multilateral bodies, and business. Concepts such as multilateralism and tripartism show great promise. Governments must engage civil society in the spirit of shared responsibility and democratic decision-making. Such changes will result in a renewal of the state's purpose and better use of international resources and expertise in governance.

The Global Virus Network: Challenging chikungunya

PubMed Central

McSweegan, Edward; Weaver, Scott C.; Lecuit, Marc; Frieman, Matthew; Morrison, Thomas E.; Hrynkow, Sharon

2016-01-01

The recent spread of chikungunya virus to the Western Hemisphere, together with the ongoing Ebola epidemic in West Africa, have highlighted the importance of international collaboration in the detection and management of disease outbreaks. In response to this need, the Global Virus Network (GVN) was formed in 2011. The GVN is a coalition of leading medical virologists in 34 affiliated laboratories in 24 countries, who collaborate to share their resources and expertise. The GVN supports research, promotes training for young scientists, serves as a technical resource for governments, businesses and international organizations, facilitates international scientific cooperation, and advocates for funding and evidence-based public policies. In response to the spread of chikungunya, the GVN formed a task force to identify research gaps and opportunities, including models of infection and disease, candidate vaccines and antivirals, epidemiology and vector control measures. Its members also serve as authoritative sources of information for the public, press, and policy-makers. This article forms part of a symposium in Antiviral Research on “Chikungunya discovers the New World”. PMID:26071007

Species co-occurrence analysis predicts management outcomes for multiple threats.

PubMed

Tulloch, Ayesha I T; Chadès, Iadine; Lindenmayer, David B

2018-03-01

Mitigating the impacts of global anthropogenic change on species is conservation's greatest challenge. Forecasting the effects of actions to mitigate threats is hampered by incomplete information on species' responses. We develop an approach to predict community restructuring under threat management, which combines models of responses to threats with network analyses of species co-occurrence. We discover that contributions by species to network co-occurrence predict their recovery under reduction of multiple threats. Highly connected species are likely to benefit more from threat management than poorly connected species. Importantly, we show that information from a few species on co-occurrence and expected responses to alternative threat management actions can be used to train a response model for an entire community. We use a unique management dataset for a threatened bird community to validate our predictions and, in doing so, demonstrate positive feedbacks in occurrence and co-occurrence resulting from shared threat management responses during ecosystem recovery.

Corporate social responsibility in global health: an exploratory study of multinational pharmaceutical firms.

PubMed

Droppert, Hayley; Bennett, Sara

2015-04-09

As pharmaceutical firms experience increasing civil society pressure to act responsibly in a changing globalized world, many are expanding and/or reforming their corporate social responsibility (CSR) strategies. We sought to understand how multinational pharmaceutical companies currently engage in CSR activities in the developing world aimed at global health impact, their motivations for doing so and how their CSR strategies are evolving. We conducted a small-scale, exploratory study combining (i) an in-depth review of publicly available data on pharmaceutical firms' CSR with (ii) interviews of representatives from 6 firms, purposively selected, from the highest earning pharmaceutical firms worldwide. Corporate social responsibility differed for each firm particularly with respect to how CSR is defined, organizational structures for managing CSR, current CSR activities, and motivations for CSR. Across the firms studied, the common CSR activities were: differential pharmaceutical pricing, strengthening developing country drug distribution infrastructure, mHealth initiatives, and targeted research and development. Primary factors that motivated CSR engagement were: reputational benefits, recruitment and employee satisfaction, better rankings in sustainability indices, entrance into new markets, long-term economic returns, and improved population health. In terms of CSR strategy, firms were at different points on a spectrum ranging from philanthropic donations to integrated systemic shared value business models. CSR is of increasing importance for multinational pharmaceutical firms yet understanding of the array of CSR strategies employed and their effects is nascent. Our study points to the need to (i) develop clearer and more standardized definitions of CSR in global health (2) strengthen indices to track CSR strategies and their public health effects in developing countries and (iii) undertake more country level studies that investigate how CSR engages with national health systems.

Sustainability is possible despite greed - Exploring the nexus between profitability and sustainability in common pool resource systems.

PubMed

Osten, Friedrich Burkhard von der; Kirley, Michael; Miller, Tim

2017-05-23

The sustainable use of common pool resources has become a significant global challenge. It is now widely accepted that specific mechanisms such as community-based management strategies, institutional responses such as resource privatization, information availability and emergent social norms can be used to constrain individual 'harvesting' to socially optimal levels. However, there is a paucity of research focused specifically on aligning profitability and sustainability goals. In this paper, an integrated mathematical model of a common pool resource game is developed to explore the nexus between the underlying costs and benefits of harvesting decisions and the sustainable level of a shared, dynamic resource. We derive optimal harvesting efforts analytically and then use numerical simulations to show that individuals in a group can learn to make harvesting decisions that lead to the globally optimal levels. Individual agents make their decision based on signals received and a trade-off between economic and ecological sustainability. When the balance is weighted towards profitability, acceptable economic and social outcomes emerge. However, if individual agents are solely driven by profit, the shared resource is depleted in the long run - sustainability is possible despite some greed, but too much will lead to over-exploitation.

Historical Responsibility for Climate Change - from countries emissions to contribution to temperature increase

NASA Astrophysics Data System (ADS)

Krapp, Mario; Gütschow, Johannes; Rocha, Marcia; Schaeffer, Michiel

2016-04-01

The notion of historical responsibility is central to the equity debate and the measure of responsibility as a countries' share of historical global emissions remains one of the essential parameters in so-called equity proposals, which attempt to distribute effort among countries in an equitable manner. The focus of this contribution is on the historical contribution of countries, but it takes it one step further: its general objective lies on estimating countries' contribution directly to the change in climate. The historical responsibility is not based on cumulative emissions but instead measured in terms of the countries' estimated contribution to the increase in global-mean surface-air temperature. This is achieved by (1) compiling a historical emissions dataset for the period from 1850 until 2012 for each individual Kyoto-greenhouse gas and each UNFCCC Party using a consistent methodology and (2) applying those historical emissions to a revised version of the so-called Policy-maker Model put forward by the Ministry of Science and Technology of the Federative Republic of Brazil, which is a simple, yet powerful tool that allows historical GHG emissions of individual countries to be directly related to their effect on global temperature changes. We estimate that the cumulative GHG emissions until 2012 from the USA, the European Union and China contribute to a total temperature increase of about 0.50°C in 2100, which is equivalent to about 50% of the temperature increase from total global GHG emissions by that year (of about 1.0°C). Respectively, the USA, the European Union, and China are responsible for 20.2%, 17.3%, and 12.1% of global temperature increase in 2100. Russian historical emissions are responsible for 0.06°C temperature increase by 2100, ranking as the fourth largest contributor to temperature increase with 6.2% of the total contribution. India ranks fifth: Indian emissions to date would contribute to roughly 0.05°C of global mean temperature increase by 2100, or about 5.3%. Brazilian historical emissions would contribute to 0.04°C to global temperature increase by 2100 or 4.4% to total temperature increase. If the European Union countries were considered independently, Germany and Great Britain would be responsible respectively to 3.9% and 3.4% of global temperature increase in 2100. We present the results on countries' historical responsibilities and then outline in detail the methodology employed to obtain the historical emissions dataset and final temperature contributions including the different approaches to derive a revised version of the Policy-maker Model, its underlying assumptions, advantages, and limitations for estimating countries' historical contribution to temperature increase.

76 FR 27127 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

Federal Register 2010, 2011, 2012, 2013, 2014

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... WisdomTree Global Real Return Fund May 5, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange... Exchange proposes to list and trade the shares (``Shares'') of the following series of the WisdomTree Trust (``Trust'') under NYSE Arca Equities Rule 8.600: WisdomTree Global Real Return Fund (``Fund''). The text of...

Spatially Explicit Trends in the Global Conservation Status of Vertebrates

PubMed Central

Rodrigues, Ana S. L.; Brooks, Thomas M.; Butchart, Stuart H. M.; Chanson, Janice; Cox, Neil; Hoffmann, Michael; Stuart, Simon N.

2014-01-01

The world's governments have committed to preventing the extinction of threatened species and improving their conservation status by 2020. However, biodiversity is not evenly distributed across space, and neither are the drivers of its decline, and so different regions face very different challenges. Here, we quantify the contribution of regions and countries towards recent global trends in vertebrate conservation status (as measured by the Red List Index), to guide action towards the 2020 target. We found that>50% of the global deterioration in the conservation status of birds, mammals and amphibians is concentrated in <1% of the surface area, 39/1098 ecoregions (4%) and eight/195 countries (4%) – Australia, China, Colombia, Ecuador, Indonesia, Malaysia, Mexico, and the United States. These countries hold a third of global diversity in these vertebrate groups, partially explaining why they concentrate most of the losses. Yet, other megadiverse countries – most notably Brazil (responsible for 10% of species but just 1% of deterioration), plus India and Madagascar – performed better in conserving their share of global vertebrate diversity. Very few countries, mostly island nations (e.g. Cook Islands, Fiji, Mauritius, Seychelles, and Tonga), have achieved net improvements. Per capita wealth does not explain these patterns, with two of the richest countries – United States and Australia – fairing conspicuously poorly. Different countries were affected by different combinations of threats. Reducing global rates of biodiversity loss will require investment in the regions and countries with the highest responsibility for the world's biodiversity, focusing on conserving those species and areas most in peril and on reducing the drivers with the highest impacts. PMID:25426636

Spatially explicit trends in the global conservation status of vertebrates.

PubMed

Rodrigues, Ana S L; Brooks, Thomas M; Butchart, Stuart H M; Chanson, Janice; Cox, Neil; Hoffmann, Michael; Stuart, Simon N

2014-01-01

The world's governments have committed to preventing the extinction of threatened species and improving their conservation status by 2020. However, biodiversity is not evenly distributed across space, and neither are the drivers of its decline, and so different regions face very different challenges. Here, we quantify the contribution of regions and countries towards recent global trends in vertebrate conservation status (as measured by the Red List Index), to guide action towards the 2020 target. We found that>50% of the global deterioration in the conservation status of birds, mammals and amphibians is concentrated in <1% of the surface area, 39/1098 ecoregions (4%) and eight/195 countries (4%) - Australia, China, Colombia, Ecuador, Indonesia, Malaysia, Mexico, and the United States. These countries hold a third of global diversity in these vertebrate groups, partially explaining why they concentrate most of the losses. Yet, other megadiverse countries - most notably Brazil (responsible for 10% of species but just 1% of deterioration), plus India and Madagascar - performed better in conserving their share of global vertebrate diversity. Very few countries, mostly island nations (e.g. Cook Islands, Fiji, Mauritius, Seychelles, and Tonga), have achieved net improvements. Per capita wealth does not explain these patterns, with two of the richest countries - United States and Australia - fairing conspicuously poorly. Different countries were affected by different combinations of threats. Reducing global rates of biodiversity loss will require investment in the regions and countries with the highest responsibility for the world's biodiversity, focusing on conserving those species and areas most in peril and on reducing the drivers with the highest impacts.

The lure of global branding.

PubMed

Aaker, D A; Joachimsthaler, E

1999-01-01

As more and more companies begin to see the world as their market, brand builders look with envy upon those businesses that appear to have created global brands--brands whose positioning, advertising strategy, personality, look, and feel are in most respects the same from one country to another. Attracted by such high-profile examples of success, these companies want to globalize their own brands. But that's a risky path to follow, according to David Aaker and Erich Joachimsthaler. Why? Because creating strong global brands takes global brand leadership. It can't be done simply by edict from on high. Specifically, companies must use organizational structures, processes, and cultures to allocate brand-building resources globally, to create global synergies, and to develop a global brand strategy that coordinates and leverages country brand strategies. Aaker and Joachimsthaler offer four prescriptions for companies seeking to achieve global brand leadership. First, companies must stimulate the sharing of insights and best practices across countries--a system in which "it won't work here" attitudes can be overcome. Second, companies should support a common global brand-planning process, one that is consistent across markets and products. Third, they should assign global managerial responsibility for brands in order to create cross-country synergies and to fight local bias. And fourth, they need to execute brilliant brand-building strategies. Before stampeding blindly toward global branding, companies need to think through the systems they have in place. Otherwise, any success they achieve is likely to be random--and that's a fail-safe recipe for mediocrity.

The necessity of nuclear reactors for targeted radionuclide therapies.

PubMed

Krijger, Gerard C; Ponsard, Bernard; Harfensteller, Mark; Wolterbeek, Hubert T; Nijsen, Johannes W F

2013-07-01

Nuclear medicine has been contributing towards personalized therapies. Nuclear reactors are required for the working horses of both diagnosis and treatment, i.e., Tc-99m and I-131. In fact, reactors will remain necessary to fulfill the demand for a variety of radionuclides and are essential in the expanding field of targeted radionuclide therapies for cancer. However, the main reactors involved in the global supply are ageing and expected to shut down before 2025. Therefore, the fields of (nuclear) medicine, nuclear industry and politics share a global responsibility, faced with the task to secure future access to suitable nuclear reactors. At the same time, alternative production routes should be industrialized. For this, a coordinating entity should be put into place. Copyright © 2013 Elsevier Ltd. All rights reserved.

Accounting for sampling patterns reverses the relative importance of trade and climate for the global sharing of exotic plants

USGS Publications Warehouse

Sofaer, Helen R.; Jarnevich, Catherine S.

2017-01-01

AimThe distributions of exotic species reflect patterns of human-mediated dispersal, species climatic tolerances and a suite of other biotic and abiotic factors. The relative importance of each of these factors will shape how the spread of exotic species is affected by ongoing economic globalization and climate change. However, patterns of trade may be correlated with variation in scientific sampling effort globally, potentially confounding studies that do not account for sampling patterns.LocationGlobal.Time periodMuseum records, generally from the 1800s up to 2015.Major taxa studiedPlant species exotic to the United States.MethodsWe used data from the Global Biodiversity Information Facility (GBIF) to summarize the number of plant species with exotic occurrences in the United States that also occur in each other country world-wide. We assessed the relative importance of trade and climatic similarity for explaining variation in the number of shared species while evaluating several methods to account for variation in sampling effort among countries.ResultsAccounting for variation in sampling effort reversed the relative importance of trade and climate for explaining numbers of shared species. Trade was strongly correlated with numbers of shared U.S. exotic plants between the United States and other countries before, but not after, accounting for sampling variation among countries. Conversely, accounting for sampling effort strengthened the relationship between climatic similarity and species sharing. Using the number of records as a measure of sampling effort provided a straightforward approach for the analysis of occurrence data, whereas species richness estimators and rarefaction were less effective at removing sampling bias.Main conclusionsOur work provides support for broad-scale climatic limitation on the distributions of exotic species, illustrates the need to account for variation in sampling effort in large biodiversity databases, and highlights the difficulty in inferring causal links between the economic drivers of invasion and global patterns of exotic species occurrence.

A cache-aided multiprocessor rollback recovery scheme

NASA Technical Reports Server (NTRS)

Wu, Kun-Lung; Fuchs, W. Kent

1989-01-01

This paper demonstrates how previous uniprocessor cache-aided recovery schemes can be applied to multiprocessor architectures, for recovering from transient processor failures, utilizing private caches and a global shared memory. As with cache-aided uniprocessor recovery, the multiprocessor cache-aided recovery scheme of this paper can be easily integrated into standard bus-based snoopy cache coherence protocols. A consistent shared memory state is maintained without the necessity of global check-pointing.

Religious affiliation at time of death - Global estimates and projections.

PubMed

Skirbekk, Vegard; Todd, Megan; Stonawski, Marcin

2018-03-01

Religious affiliation influences societal practices regarding death and dying, including palliative care, religiously acceptable health service procedures, funeral rites and beliefs about an afterlife. We aimed to estimate and project religious affiliation at the time of death globally, as this information has been lacking. We compiled data on demographic information and religious affiliation from more than 2500 surveys, registers and censuses covering 198 nations/territories. We present estimates of religious affiliation at the time of death as of 2010, projections up to and including 2060, taking into account trends in mortality, religious conversion, intergenerational transmission of religion, differential fertility, and gross migration flows, by age and sex. We find that Christianity continues to be the most common religion at death, although its share will fall from 37% to 31% of global deaths between 2010 and 2060. The share of individuals identifying as Muslim at the time of death increases from 21% to 24%. The share of religiously unaffiliated will peak at 17% in 2035 followed by a slight decline thereafter. In specific regions, such as Europe, the unaffiliated share will continue to rises from 14% to 21% throughout the period. Religious affiliation at the time of death is changing globally, with distinct regional patterns. This could affect spatial variation in healthcare and social customs relating to death and dying.

The Global Health Dimensions of Asbestos and Asbestos-Related Diseases.

PubMed

Takahashi, Ken; Landrigan, Philip J

2016-01-01

The Collegium Ramazzini (CR) reaffirms its long-standing position that responsible public health action is to ban all extraction and use of asbestos, including chrysotile. This current statement updates earlier statements by the CR with a focus on global health dimensions of asbestos and asbestos-related diseases (ARDs). The ARD epidemic will likely not peak for at least a decade in most industrialized countries and for several decades in industrializing countries. Asbestos and ARDs will continue to present challenges in the arena of occupational medicine and public health, as well as in clinical research and practice, and have thus emerged as a global health issue. Industrialized countries that have already gone through the transition to an asbestos ban have learned lessons and acquired know-how and capacity that could be of great value if deployed in industrializing countries embarking on the transition. The accumulated wealth of experience and technologies in industrialized countries should thus be shared internationally through global campaigns to eliminate ARDs. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Shared learning in an interconnected world: innovations to advance global health equity

PubMed Central

2013-01-01

The notion of “reverse innovation”--that some insights from low-income countries might offer transferable lessons for wealthier contexts--is increasingly common in the global health and business strategy literature. Yet the perspectives of researchers and policymakers in settings where these innovations are developed have been largely absent from the discussion to date. In this Commentary, we present examples of programmatic, technological, and research-based innovations from Rwanda, and offer reflections on how the global health community might leverage innovative partnerships for shared learning and improved health outcomes in all countries. PMID:24119388

Task Group on a Culture of Savings: Implementing Behavior Change in DoD

DTIC Science & Technology

2011-01-01

Robert Hale Task Group Chairman – Navy Future Personnel and Pay Solution (FPPS) - Business Case November 30, 2009 – Case for Shared Services in the...Public Sector - Accenture Shared Services in Government - AT Kearney – 2009 Global Shared Services Survey Results - Deloitte – Shared Services - a...Benchmark Study - The Johnson Group – Economics of Business Process Outsourcing - Technology Association of Georgia – State of Shared Services and Business

Report To The Secretary Of Defense-Task Group On A Culture Of Savings: Implementing Behavior Change In DoD

DTIC Science & Technology

2011-01-01

Shared Services in the Public Sector - Accenture Shared Services in Government - AT Kearney – 2009 Global Shared Services Survey Results - Deloitte... Shared Services - a Benchmark Study - The Johnson Group – Economics of Business Process Outsourcing - Technology Association of Georgia – State of... Shared Services and Business Process Outsourcing - Accenture – Public Sector Outsourcing Surge in 2010 - National Outsourcing Association – Naval

The Ebola Outbreak: Catalyzing a "Shift" in Global Health Governance?

PubMed

Mackey, Tim K

2016-11-24

As the 2014 Ebola virus disease outbreak (EVD) transitions to its post-endemic phase, its impact on the future of global public health, particularly the World Health Organization (WHO), is the subject of continued debate. Criticism of WHO's performance grew louder in the outbreak's wake, placing this international health UN-specialized agency in the difficult position of navigating a complex series of reform recommendations put forth by different stakeholders. Decisions on WHO governance reform and the broader role of the United Nations could very well shape the future landscape of 21st century global health and how the international community responds to health emergencies. In order to better understand the implications of the EVD outbreak on global health and infectious disease governance, this debate article critically examines a series of reports issued by four high-level commissions/panels convened to specifically assess WHO's performance post-Ebola. Collectively, these recommendations add increasing complexity to the urgent need for WHO reform, a process that the agency must carry out in order to maintain its legitimacy. Proposals that garnered strong support included the formation of an independent WHO Centre for Emergency Preparedness and Response, the urgent need to increase WHO infectious disease funding and capacity, and establishing better operational and policy coordination between WHO, UN agencies, and other global health partners. The recommendations also raise more fundamental questions about restructuring the global health architecture, and whether the UN should play a more active role in global health governance. Despite the need for a fully modernized WHO, reform proposals recently announced by WHO fail to achieve the "evolution" in global health governance needed in order to ensure that global society is adequately protected against the multifaceted and increasingly complex nature of modern public health emergencies. Instead, the lasting legacy of the EVD outbreak may be its foreshadowing of a governance "shift" in formal sharing of the complex responsibilities of global health, health security, outbreak response, and managing health emergencies to other international structures, most notably the United Nations. Only time will tell if the legacy of EVD will include a WHO that has the full support of the international community and is capable of leading human society in this brave new era of the globalization of infectious diseases.

Global polio eradication initiative: lessons learned and legacy.

PubMed

Cochi, Stephen L; Freeman, Andrew; Guirguis, Sherine; Jafari, Hamid; Aylward, Bruce

2014-11-01

The world is on the verge of achieving global polio eradication. During >25 years of operations, the Global Polio Eradication Initiative (GPEI) has mobilized and trained millions of volunteers, social mobilizers, and health workers; accessed households untouched by other health initiatives; mapped and brought health interventions to chronically neglected and underserved communities; and established a standardized, real-time global surveillance and response capacity. It is important to document the lessons learned from polio eradication, especially because it is one of the largest ever global health initiatives. The health community has an obligation to ensure that these lessons and the knowledge generated are shared and contribute to real, sustained changes in our approach to global health. We have summarized what we believe are 10 leading lessons learned from the polio eradication initiative. We have the opportunity and obligation to build a better future by applying the lessons learned from GPEI and its infrastructure and unique functions to other global health priorities and initiatives. In so doing, we can extend the global public good gained by ending for all time one of the world's most devastating diseases by also ensuring that these investments provide public health dividends and benefits for years to come. Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Ethical issues in funding research and development of drugs for neglected tropical diseases.

PubMed

Oprea, L; Braunack-Mayer, A; Gericke, C A

2009-05-01

Neglected and tropical diseases, pervasive in developing countries, are important contributors to global health inequalities. They remain largely untreated due to lack of effective and affordable treatments. Resource-poor countries cannot afford to develop the public health interventions needed to control neglected diseases. In addition, neglected diseases do not represent an attractive market for pharmaceutical industry. Although a number of international commitments, stated in the Millennium Development Goals, have been made to avert the risk of communicable diseases, tropical diseases still remain neglected due to delays in international assistance. This delay can be explained by the form international cooperation has generally taken, which is limited to promoting countries' national interests, rather than social justice at a global level. This restricts the international responsibility for global inequalities in health to a humanitarian assistance. We propose an alternative view, arguing that expanding the scope of international cooperation by promoting shared health and economic value at a global level will create new opportunities for innovative, effective and affordable interventions worldwide. It will also promote neglected diseases as a global research priority. We build our argument on a proposal to replace the patenting system that currently regulates pharmaceutical research with a global fund to reward this research based on actual decreases in morbidity and mortality at a global level. We argue that this approach is beneficent because it will decrease global health inequalities and promote social justice worldwide.

Implementing Journaling in a Linux Shared Disk File System

NASA Technical Reports Server (NTRS)

Preslan, Kenneth W.; Barry, Andrew; Brassow, Jonathan; Cattelan, Russell; Manthei, Adam; Nygaard, Erling; VanOort, Seth; Teigland, David; Tilstra, Mike; O'Keefe, Matthew;

Enlarging the Human Dimensions of Earth System Science

NASA Astrophysics Data System (ADS)

Seielstad, G. A.; Rattling Leaf, J.

2005-12-01

Sustainability, meaning meeting human needs and values while also preserving Earth's life-support systems, can only be achieved if a just and equitable distribution of access to natural resources exists. The same environment is shared by all peoples; all must have an interest in preserving it; therefore all must receive a fair share of the benefits that preservation allows. As with most sustainability objectives, the most effective strategy remains to "think globally but act locally." In the Northern Great Plains, the Upper Midwest Aerospace Consortium (UMAC) is committed to providing leadership toward sustainability. UMAC realized it needed to serve its region's largest minority, Native Americans, in order to nurture regionally the type of just society a sustainable system demands. The consortium therefore added a tribal university, Sinte Gleska, to its original seven partners. SGU shares with the other consortium universities the longer history Native Americans have with the region's environment and the closer connection they experience to Nature. Both cultures, indigenous and western, benefit. A path has been set that allows Sinte Gleska University to help organize a parallel consortium of tribal colleges committed to economic benefit and responsible planetary stewardship.

Mathematical Modeling of Language Games

NASA Astrophysics Data System (ADS)

Loreto, Vittorio; Baronchelli, Andrea; Puglisi, Andrea

In this chapter we explore several language games of increasing complexity. We first consider the so-called Naming Game, possibly the simplest example of the complex processes leading progressively to the establishment of human-like languages. In this framework, a globally shared vocabulary emerges as a result of local adjustments of individual word-meaning association. The emergence of a common vocabulary only represents a first stage while it is interesting to investigate the emergence of higher forms of agreement, e.g., compositionality, categories, syntactic or grammatical structures. As an example in this direction we consider the so-called Category Game. Here one focuses on the process by which a population of individuals manages to categorize a single perceptually continuous channel. The problem of the emergence of a discrete shared set of categories out of a continuous perceptual channel is a notoriously difficult problem relevant for color categorization, vowels formation, etc. The central result here is the emergence of a hierarchical category structure made of two distinct levels: a basic layer, responsible for fine discrimination of the environment, and a shared linguistic layer that groups together perceptions to guarantee communicative success.

Empowering Faculty to Develop and Share Global Knowledge

ERIC Educational Resources Information Center

Harrison, David

2014-01-01

As colleges seek to increase global knowledge within its students, it is important that faculty members are also offered opportunities to increase their own knowledge of global issues. This chapter discusses faculty development models for seminars abroad and how these seminars encourage the development of unique global study programs.

Strengthening routine immunization systems to improve global vaccination coverage.

PubMed

Sodha, S V; Dietz, V

2015-03-01

Global coverage with the third dose of diphtheria-tetanus-pertussis vaccine among children under 1 year of age stagnated at ∼ 83-84% during 2008-13. Annual World Health Organization and UNICEF-derived national vaccination coverage estimates. Incomplete vaccination is associated with poor socioeconomic status, lower education, non-use of maternal-child health services, living in conflict-affected areas, missed immunization opportunities and cancelled vaccination sessions. Vaccination platforms must expand to include older ages including the second year of life. Immunization programmes, including eradication and elimination initiatives such as those for polio and measles, must integrate within the broader health system. The Global Vaccine Action Plan (GVAP) 2011-20 is a framework for strengthening immunization systems, emphasizing country ownership, shared responsibility, equity, integration, sustainability and innovation. Immunization programmes should identify, monitor and evaluate gaps and interventions within the GVAP framework. Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entomological Opportunities and Challenges for Sustainable Viticulture in a Global Market.

PubMed

Daane, Kent M; Vincent, Charles; Isaacs, Rufus; Ioriatti, Claudio

2018-01-07

Viticulture has experienced dramatic global growth in acreage and value. As the international exchange of goods has increased, so too has the market demand for sustainably produced products. Both elements redefine the entomological challenges posed to viticulture and have stimulated significant advances in arthropod pest control programs. Vineyard managers on all continents are increasingly combating invasive species, resulting in the adoption of novel insecticides, semiochemicals, and molecular tools to support sustainable viticulture. At the local level, vineyard management practices consider factors such as the surrounding natural ecosystem, risk to fish populations, and air quality. Coordinated multinational responses to pest invasion have been highly effective and have, for example, resulted in eradication of the moth Lobesia botrana from California vineyards, a pest found in 2009 and eradicated by 2016. At the global level, the shared pests and solutions for their suppression will play an increasing role in delivering internationally sensitive pest management programs that respond to invasive pests, climate change, novel vector and pathogen relationships, and pesticide restrictions.

Shared control of gene expression in bacteria by transcription factors and global physiology of the cell

PubMed Central

Berthoumieux, Sara; de Jong, Hidde; Baptist, Guillaume; Pinel, Corinne; Ranquet, Caroline; Ropers, Delphine; Geiselmann, Johannes

2013-01-01

Gene expression is controlled by the joint effect of (i) the global physiological state of the cell, in particular the activity of the gene expression machinery, and (ii) DNA-binding transcription factors and other specific regulators. We present a model-based approach to distinguish between these two effects using time-resolved measurements of promoter activities. We demonstrate the strength of the approach by analyzing a circuit involved in the regulation of carbon metabolism in E. coli. Our results show that the transcriptional response of the network is controlled by the physiological state of the cell and the signaling metabolite cyclic AMP (cAMP). The absence of a strong regulatory effect of transcription factors suggests that they are not the main coordinators of gene expression changes during growth transitions, but rather that they complement the effect of global physiological control mechanisms. This change of perspective has important consequences for the interpretation of transcriptome data and the design of biological networks in biotechnology and synthetic biology. PMID:23340840

Parent-adolescent dyads: association of parental autonomy support and parent-adolescent shared diabetes care responsibility.

PubMed

Hanna, K M; Dashiff, C J; Stump, T E; Weaver, M T

2013-09-01

Parent-adolescent shared responsibility for diabetes care is advocated by experts to achieve beneficial diabetes and psychosocial outcomes for adolescents with type 1 diabetes. Parental autonomy support may be a way to facilitate this sharing. In this dyadic study, we examined parental diabetes-specific autonomy support experienced by adolescents with type 1 diabetes and their parents (n = 89 dyads), and its association with their experience of shared diabetes care responsibility. Path analysis was used to test an Actor-Partner Interdependence Model for parental autonomy support effects on shared responsibility. This was a secondary analysis of data from 89 parent-early/mid-adolescent dyads. Actor effects were identified. Parents' and adolescents' perceptions of parental autonomy support were associated with their respective reports of shared diabetes care responsibility. One partner effect was identified. Adolescents' reports of parental autonomy support were associated with parents' reports of shared responsibility. Parents and adolescents held similar views of autonomy support but discrepant views of shared responsibility. Older adolescents perceived less parental autonomy support. Increasing parental autonomy support may facilitate parent-adolescent sharing of diabetes care responsibility. Adolescent and parent perceptions influence each other and need to be considered when working with them to strengthen parental autonomy support. © 2012 John Wiley & Sons Ltd.

KT&G: From Korean monopoly to 'a global name in the tobacco industry'.

PubMed

Lee, Kelley; Gong, Lucy; Eckhardt, Jappe; Holden, Chris; Lee, Sungkyu

2017-03-01

Until the late 1980s, the former South Korean tobacco monopoly KT&G was focused on the protected domestic market. The opening of the market to foreign competition, under pressure from the U.S. Trade Representative, led to a steady erosion of market share over the next 10 years. Drawing on company documents and industry sources, this paper examines the adaptation of KT&G to the globalization of the South Korean tobacco industry since the 1990s. It is argued that KT&G has shifted from a domestic monopoly to an outward-looking, globally oriented business in response to the influx of transnational tobacco companies. Like other high-income countries, South Korea has also seen a decline in smoking prevalence as stronger tobacco control measures have been adopted. Faced with a shrinking domestic market, KT&G initially focused on exporting Korean-manufactured cigarettes. Since the mid-2000s, a broader global business strategy has been adopted including the building of overseas manufacturing facilities, establishing strategic partnerships and acquiring foreign companies. Trends in KT&G sales suggest an aspiring transnational tobacco company poised to become a major player in the global tobacco market. This article is part of the special issue 'The emergence of Asian tobacco companies: Implications for global health governance'.

KT&G: From Korean monopoly to ‘a global name in the tobacco industry’

PubMed Central

Lee, Kelley; Gong, Lucy; Eckhardt, Jappe; Holden, Chris; Lee, Sungkyu

2017-01-01

ABSTRACT Until the late 1980s, the former South Korean tobacco monopoly KT&G was focused on the protected domestic market. The opening of the market to foreign competition, under pressure from the U.S. Trade Representative, led to a steady erosion of market share over the next 10 years. Drawing on company documents and industry sources, this paper examines the adaptation of KT&G to the globalization of the South Korean tobacco industry since the 1990s. It is argued that KT&G has shifted from a domestic monopoly to an outward-looking, globally oriented business in response to the influx of transnational tobacco companies. Like other high-income countries, South Korea has also seen a decline in smoking prevalence as stronger tobacco control measures have been adopted. Faced with a shrinking domestic market, KT&G initially focused on exporting Korean-manufactured cigarettes. Since the mid-2000s, a broader global business strategy has been adopted including the building of overseas manufacturing facilities, establishing strategic partnerships and acquiring foreign companies. Trends in KT&G sales suggest an aspiring transnational tobacco company poised to become a major player in the global tobacco market. This article is part of the special issue ‘The emergence of Asian tobacco companies: Implications for global health governance’. PMID:28139963

Costs and global impacts of black carbon abatement strategies

NASA Astrophysics Data System (ADS)

Rypdal, Kristin; Rive, Nathan; Berntsen, Terje K.; Klimont, Zbigniew; Mideksa, Torben K.; Myhre, Gunnar; Skeie, Ragnhild B.

2009-09-01

Abatement of particulate matter has traditionally been driven by health concerns rather than its role in global warming. Here we assess future abatement strategies in terms of how much they reduce the climate impact of black carbon (BC) and organic carbon (OC) from contained combustion. We develop global scenarios which take into account regional differences in climate impact, costs of abatement and ability to pay, as well as both the direct and indirect (snow-albedo) climate impact of BC and OC. To represent the climate impact, we estimate consistent region-specific values of direct and indirect global warming potential (GWP) and global temperature potential (GTP). The indirect GWP has been estimated using a physical approach and includes the effect of change in albedo from BC deposited on snow. The indirect GWP is highest in the Middle East followed by Russia, Europe and North America, while the total GWP is highest in the Middle East, Africa and South Asia. We conclude that prioritizing emission reductions in Asia represents the most cost-efficient global abatement strategy for BC because Asia is (1) responsible for a large share of total emissions, (2) has lower abatement costs compared to Europe and North America and (3) has large health cobenefits from reduced PM10 emissions.

Late Multiple Organ Surge in Interferon-Regulated Target Genes Characterizes Staphylococcal Enterotoxin B Lethality

PubMed Central

Ferreyra, Gabriela A.; Elinoff, Jason M.; Demirkale, Cumhur Y.; Starost, Matthew F.; Buckley, Marilyn; Munson, Peter J.; Krakauer, Teresa; Danner, Robert L.

2014-01-01

Background Bacterial superantigens are virulence factors that cause toxic shock syndrome. Here, the genome-wide, temporal response of mice to lethal intranasal staphylococcal enterotoxin B (SEB) challenge was investigated in six tissues. Results The earliest responses and largest number of affected genes occurred in peripheral blood mononuclear cells (PBMC), spleen, and lung tissues with the highest content of both T-cells and monocyte/macrophages, the direct cellular targets of SEB. In contrast, the response of liver, kidney, and heart was delayed and involved fewer genes, but revealed a dominant genetic program that was seen in all 6 tissues. Many of the 85 uniquely annotated transcripts participating in this shared genomic response have not been previously linked to SEB. Nine of the 85 genes were subsequently confirmed by RT-PCR in every tissue/organ at 24 h. These 85 transcripts, up-regulated in all tissues, annotated to the interferon (IFN)/antiviral-response and included genes belonging to the DNA/RNA sensing system, DNA damage repair, the immunoproteasome, and the ER/metabolic stress-response and apoptosis pathways. Overall, this shared program was identified as a type I and II interferon (IFN)-response and the promoters of these genes were highly enriched for IFN regulatory matrices. Several genes whose secreted products induce the IFN pathway were up-regulated at early time points in PBMCs, spleen, and/or lung. Furthermore, IFN regulatory factors including Irf1, Irf7 and Irf8, and Zbp1, a DNA sensor/transcription factor that can directly elicit an IFN innate immune response, participated in this host-wide SEB signature. Conclusion Global gene-expression changes across multiple organs implicated a host-wide IFN-response in SEB-induced death. Therapies aimed at IFN-associated innate immunity may improve outcome in toxic shock syndromes. PMID:24551153

76 FR 54498 - Meeting of the Department of Justice Global Justice Information Sharing Initiative Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-01

... (GAC) to discuss the Global Initiative, as described at http://www.it.ojp.gov/global . DATES: [email protected]gov . SUPPLEMENTARY INFORMATION: This meeting is open to the public. Due to security measures...

75 FR 56557 - Meeting of the Department of Justice's (DOJ's) Global Justice Information Sharing Initiative...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-16

... Committee (GAC) to discuss the Global Initiative, as described at http://www.it.ojp.gov/global . DATES: [email protected]gov . SUPPLEMENTARY INFORMATION: This meeting is open to the public. Due to security measures...

Global challenges of graduate level Ayurvedic education: A survey

PubMed Central

Patwardhan, Kishor; Gehlot, Sangeeta; Singh, Girish; Rathore, H.C.S.

2010-01-01

In the present day scenario, Ayurveda is globally being perceived in several contradictory ways. Poor quality of Ayurveda graduates produced as a result of poorly structured and poorly regulated education system is at least one of the important factors responsible for this scenario. The present study was carried out to evaluate the ‘Global challenges of graduate level Ayurvedic education’ and is based on the responses of Ayurvedic students and Ayurvedic teachers from various educational institutions of India to a methodically validated questionnaire. As the study indicates, the poor standard of Ayurvedic education in India is definitely a cause of concern. The curriculum of Bachelor of Ayurvedic Medicine and Surgery (BAMS) course of studies is required to be reviewed and restructured. The syllabi are required to be updated with certain relevant topics like laws governing the intellectual property rights, basic procedures of standardization of medicinal products, fundamental methods of evaluating the toxicity of the medicinal products, essentials of healthcare management and the basics of cultivation and marketing of medicinal plants. Furthermore, the study suggests that the Ayurvedic academicians are required to be trained in standard methods of research and documentation skills, and the educational institutions are required to be encouraged to contribute their share in building up the evidence base for Ayurveda in the form of quality education and research. PMID:20532099

78 FR 66798 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Instituting...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-06

... shares traded. Specifically, the Exchange states that, according to State Street Global Advisor, the... to the Exchange, for the three months ending on June 20, 2013, the average daily volume in SPY shares was 137 million, and the average value of shares traded was $22.1 billion. According to the Exchange...

Nurse manager perspective of staff participation in unit level shared governance.

PubMed

Cox Sullivan, Sheila; Norris, Mitzi R; Brown, Lana M; Scott, Karen J

2017-11-01

To examine the nurse manager perspective surrounding implementation of unit level shared governance in one Veterans Health Administration facility. Nursing shared governance is a formal model allowing nursing staff decision-making input into clinical practice, quality improvement, evidence-based practice and staff professional development. Unit level shared governance is a management process where decision authority is delegated to nursing staff at the unit level. Convenience sampling was used to recruit ten nurse managers who participated in face-to-face semi-structured interviews. Data were analysed using content analysis and constant comparison techniques. Demographic data were described using descriptive statistics. The participants included seven female and three male nurse managers with seven Caucasian and three African American. Participant quotes were clustered to identify sub-themes that were then grouped into four global themes to describe unit level shared governance. The global themes were: (1) motivation, (2) demotivation, (3) recommendations for success, and (4) outcomes. These research findings resonate with previous studies that shared governance may be associated with increased nurse empowerment, self-management, engagement, and satisfaction. These findings reflect the need for nurse managers to promote and recognize staff participation in unit level shared governance. © 2017 John Wiley & Sons Ltd.

65 Years of influenza surveillance by a WHO-coordinated global network.

PubMed

Ziegler, Thedi; Mamahit, Awandha; Cox, Nancy J

2018-05-04

The 1918 devastating influenza pandemic left a lasting impact on influenza experts and the public, and the importance of global influenza surveillance was soon recognized. The WHO Global Influenza Surveillance Network (GISN) was founded in 1952 and renamed to Global Influenza Surveillance and Response System in 2011 upon the adoption by the World Health Assembly, of the Pandemic Influenza Preparedness Framework for the Sharing of Influenza Viruses and Access to Vaccines and Other Benefits ("PIP Framework"). The importance of influenza surveillance had been recognized and promoted by experts prior to the years leading up to the establishment of WHO. In the 65 years of its existence, the Network has grown to comprise 143 National Influenza Centers recognized by WHO, 6 WHO Collaborating Centers, 4 Essential Regulatory Laboratories, and 13 H5 Reference Laboratories. The Network has proven its excellence throughout these 65 years, providing detailed information on circulating seasonal influenza viruses, as well as immediate response to the influenza pandemics in 1957, 1968, and 2009, and to threats caused by animal influenza viruses and by zoonotic transmission of coronaviruses. For its central role in global public health, the Network has been highly recognized by its many partners and by international bodies. Several generations of world renown influenza scientists have brought the Network to where it is now and they will take it forward to the future, as influenza will remain a pre-eminent threat to humans and to animals. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Global emergency medicine journal club: social media responses to the march 2014 annals of emergency medicine journal club on targeted temperature management.

PubMed

Thoma, Brent; Rolston, Daniel; Lin, Michelle

2014-08-01

In March 2014, Annals of Emergency Medicine continued a successful collaboration with an academic Web site, Academic Life in Emergency Medicine (ALiEM), to host another Global Emergency Medicine Journal Club session featuring the 2013 New England Journal of Medicine article "Targeted Temperature Management at 33°C (91.4°F) Versus 36°C (96.8°F) After Cardiac Arrest" by Nielsen et al. This online journal club used Twitter conversations, a live videocast with the authors, and detailed discussions on the ALiEM Web site's comment section. This summary article details the community discussion, shared insights, and analytic data generated using this novel, multiplatform approach. Copyright © 2014 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

Using Critical Cosmopolitanism to Globally Situate Multicultural Education in Teacher Preparation Courses

ERIC Educational Resources Information Center

Byker, Erik Jon; Marquardt, Sheila K.

2016-01-01

Globally-minded teachers often beget globally-minded students. The same relationship seems to hold true for multiculturalism; teachers who are committed to multiculturalism often nudge students toward the same commitment. Global citizenship and multicultural education share a strong bond. Yet, in the field of social studies teacher preparation,…

Hidden concerns of sharing research data by low/middle-income country scientists.

PubMed

Bezuidenhout, Louise; Chakauya, Ereck

2018-01-01

There has considerable interest in bringing low/middle-income countries (LMIC) scientists into discussions on Open Data - both as contributors and users. The establishment of in situ data sharing practices within LMIC research institutions is vital for the development of an Open Data landscape in the Global South. Nonetheless, many LMICs have significant challenges - resource provision, research support and extra-laboratory infrastructures. These low-resourced environments shape data sharing activities, but are rarely examined within Open Data discourse. In particular, little attention is given to how these research environments shape scientists' perceptions of data sharing (dis)incentives. This paper expands on these issues of incentivizing data sharing, using data from a quantitative survey disseminated to life scientists in 13 countries in sub-Saharan Africa. This interrogated not only perceptions of data sharing amongst LMIC scientists, but also how these are connected to the research environments and daily challenges experienced by them. The paper offers a series of analysis around commonly cited (dis)incentives such as data sharing as a means of improving research visibility; sharing and funding; and online connectivity. It identifies key areas that the Open Data community need to consider if true openness in research is to be established in the Global South.

From individual innovation to global impact: the Global Cooperation on Assistive Technology (GATE) innovation snapshot as a method for sharing and scaling.

PubMed

Layton, Natasha; Murphy, Caitlin; Bell, Diane

2018-07-01

Assistive technology (AT) is an essential facilitator of independence and participation, both for people living with the effects of disability and/or non-communicable disease, as well as people aging with resultant functional decline. The World Health Organization (WHO) recognizes the substantial gap between the need for and provision of AT and is leading change through the Global Cooperation on Assistive Technology (GATE) initiative. Showcasing innovations gathered from 92 global researchers, innovators, users and educators of AT through the WHO GREAT Summit, this article provides an analysis of ideas and actions on a range of dimensions in order to provide a global overview of AT innovation. The accessible method used to capture and showcase this data is presented and critiqued, concluding that "innovation snapshots" are a rapid and concise strategy to capture and showcase AT innovation and to foster global collaboration. Implications for Rehabilitation Focal tools such as ePosters with uniform data requirements enable the rapid sharing of information. A diversity of innovative practices are occurring globally in the areas of AT Products, Policy, Provision, People and Personnel. The method offered for Innovation Snapshots had substantial uptake and is a feasible means to capture data across a range of stakeholders. Meeting accessibility criteria is an emerging competency in the AT community. Substantial areas of common interest exist across regions and globally in the AT community, demonstrating the effectiveness of information sharing platforms such as GATE and supporting the idea of regional forums and networks.

24 CFR 982.515 - Family share: Family responsibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Family share: Family responsibility... Assistance Payment § 982.515 Family share: Family responsibility. (a) The family share is calculated by subtracting the amount of the housing assistance payment from the gross rent. (b) The family rent to owner is...

24 CFR 982.515 - Family share: Family responsibility.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Family share: Family responsibility... Assistance Payment § 982.515 Family share: Family responsibility. (a) The family share is calculated by subtracting the amount of the housing assistance payment from the gross rent. (b) The family rent to owner is...

Structure of health-care dyad leadership: an organization's experience.

PubMed

Saxena, Anurag; Davies, Maura; Philippon, Don

2018-05-08

Purpose This study aims to explore the structural aspects (roles, responsibilities and reporting) of dyad leadership in one health-care organization (HCO). Design/methodology/approach The perceptions of 32 leaders (17 physician leaders and 15 dyad co-leaders) in formal leadership positions (six first-level with formal authority limited to teams or divisions, 23 middle-level with wider departmental or program responsibility and three senior-level with institution-wide authority) were obtained through focus groups and surveys. In addition, five senior leaders were interviewed. Descriptive statistics was used for quantitative data, and qualitative data were analyzed for themes by coding and categorization. Findings There are a large number of shared responsibilities in the hybrid model, as most activities in HCOs bridge administrative and professional spheres. These span the leadership (e.g. global performance and quality improvement) and management (e.g. human resources, budgets and education delivery) domains. The individual responsibilities, except for staff and physician engagement are in the management domain (e.g. operations and patient care). Both partners are responsible for joint decision-making, projecting a united front and joint reporting through a quadrat format. The mutual relationship and joint accountability are key characteristics and are critical to addressing potential conflicts and contradictions and achieving coherence. Practical implications Clarity of role will assist development of standardized job descriptions and required competencies, recruitment and leadership development. Originality/value This is an original empirical study presenting an integrated view of dyad leaders and senior leadership, meaningful expansion of shared responsibilities including academic functions and developing mutual relationship and emphasizing the central role of stability generating management functions.

Global Access-controlled Transfer e-frame (GATe)

DOE Office of Scientific and Technical Information (OSTI.GOV)

2012-05-30

Global Access-controlled Transfer e-frame (GATe) was designed to take advantage of the patterns that occur during an electronic record transfer process. The e-frame (or electronic framework or platform) is the foundation for developing secure information transfer to meet classified and unclassified business processes and is particularly useful when there is a need to share information with various entities in a controlled and secure environment. It can share, search, upload, download and retrieve sensitive information, as well as provides reporting capabilities.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

PubMed

Wang, Mingxun; Carver, Jeremy J; Phelan, Vanessa V; Sanchez, Laura M; Garg, Neha; Peng, Yao; Nguyen, Don Duy; Watrous, Jeramie; Kapono, Clifford A; Luzzatto-Knaan, Tal; Porto, Carla; Bouslimani, Amina; Melnik, Alexey V; Meehan, Michael J; Liu, Wei-Ting; Crüsemann, Max; Boudreau, Paul D; Esquenazi, Eduardo; Sandoval-Calderón, Mario; Kersten, Roland D; Pace, Laura A; Quinn, Robert A; Duncan, Katherine R; Hsu, Cheng-Chih; Floros, Dimitrios J; Gavilan, Ronnie G; Kleigrewe, Karin; Northen, Trent; Dutton, Rachel J; Parrot, Delphine; Carlson, Erin E; Aigle, Bertrand; Michelsen, Charlotte F; Jelsbak, Lars; Sohlenkamp, Christian; Pevzner, Pavel; Edlund, Anna; McLean, Jeffrey; Piel, Jörn; Murphy, Brian T; Gerwick, Lena; Liaw, Chih-Chuang; Yang, Yu-Liang; Humpf, Hans-Ulrich; Maansson, Maria; Keyzers, Robert A; Sims, Amy C; Johnson, Andrew R; Sidebottom, Ashley M; Sedio, Brian E; Klitgaard, Andreas; Larson, Charles B; P, Cristopher A Boya; Torres-Mendoza, Daniel; Gonzalez, David J; Silva, Denise B; Marques, Lucas M; Demarque, Daniel P; Pociute, Egle; O'Neill, Ellis C; Briand, Enora; Helfrich, Eric J N; Granatosky, Eve A; Glukhov, Evgenia; Ryffel, Florian; Houson, Hailey; Mohimani, Hosein; Kharbush, Jenan J; Zeng, Yi; Vorholt, Julia A; Kurita, Kenji L; Charusanti, Pep; McPhail, Kerry L; Nielsen, Kristian Fog; Vuong, Lisa; Elfeki, Maryam; Traxler, Matthew F; Engene, Niclas; Koyama, Nobuhiro; Vining, Oliver B; Baric, Ralph; Silva, Ricardo R; Mascuch, Samantha J; Tomasi, Sophie; Jenkins, Stefan; Macherla, Venkat; Hoffman, Thomas; Agarwal, Vinayak; Williams, Philip G; Dai, Jingqui; Neupane, Ram; Gurr, Joshua; Rodríguez, Andrés M C; Lamsa, Anne; Zhang, Chen; Dorrestein, Kathleen; Duggan, Brendan M; Almaliti, Jehad; Allard, Pierre-Marie; Phapale, Prasad; Nothias, Louis-Felix; Alexandrov, Theodore; Litaudon, Marc; Wolfender, Jean-Luc; Kyle, Jennifer E; Metz, Thomas O; Peryea, Tyler; Nguyen, Dac-Trung; VanLeer, Danielle; Shinn, Paul; Jadhav, Ajit; Müller, Rolf; Waters, Katrina M; Shi, Wenyuan; Liu, Xueting; Zhang, Lixin; Knight, Rob; Jensen, Paul R; Palsson, Bernhard O; Pogliano, Kit; Linington, Roger G; Gutiérrez, Marcelino; Lopes, Norberto P; Gerwick, William H; Moore, Bradley S; Dorrestein, Pieter C; Bandeira, Nuno

2016-08-09

The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry (MS) techniques are well-suited to high-throughput characterization of NP, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social Molecular Networking (GNPS; http://gnps.ucsd.edu), an open-access knowledge base for community-wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of 'living data' through continuous reanalysis of deposited data.

Building Shared Responsibility for Student Learning.

ERIC Educational Resources Information Center

Conzemius, Anne; O'Neill, Jan

Shared responsibility for student learning is neither a program nor a curriculum. It incorporates a set of principles and techniques that gives members of a school community the authority and responsibility to create what is needed, based on the data and culture of their particular school and school district. Sharing responsibility for student…

Combining Distributed and Shared Memory Models: Approach and Evolution of the Global Arrays Toolkit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieplocha, Jarek; Harrison, Robert J.; Kumar, Mukul

2002-07-29

Both shared memory and distributed memory models have advantages and shortcomings. Shared memory model is much easier to use but it ignores data locality/placement. Given the hierarchical nature of the memory subsystems in the modern computers this characteristic might have a negative impact on performance and scalability. Various techniques, such as code restructuring to increase data reuse and introducing blocking in data accesses, can address the problem and yield performance competitive with message passing[Singh], however at the cost of compromising the ease of use feature. Distributed memory models such as message passing or one-sided communication offer performance and scalability butmore » they compromise the ease-of-use. In this context, the message-passing model is sometimes referred to as?assembly programming for the scientific computing?. The Global Arrays toolkit[GA1, GA2] attempts to offer the best features of both models. It implements a shared-memory programming model in which data locality is managed explicitly by the programmer. This management is achieved by explicit calls to functions that transfer data between a global address space (a distributed array) and local storage. In this respect, the GA model has similarities to the distributed shared-memory models that provide an explicit acquire/release protocol. However, the GA model acknowledges that remote data is slower to access than local data and allows data locality to be explicitly specified and hence managed. The GA model exposes to the programmer the hierarchical memory of modern high-performance computer systems, and by recognizing the communication overhead for remote data transfer, it promotes data reuse and locality of reference. This paper describes the characteristics of the Global Arrays programming model, capabilities of the toolkit, and discusses its evolution.« less

Leveraging non-binding instruments for global health governance: reflections from the Global AIDS Reporting Mechanism for WHO reform.

PubMed

Taylor, A L; Alfven, T; Hougendobler, D; Tanaka, S; Buse, K

2014-02-01

As countries contend with an increasingly complex global environment with direct implications for population health, the international community is seeking novel mechanisms to incentivize coordinated national and international action towards shared health goals. Binding legal instruments have garnered increasing attention since the World Health Organization adopted its first convention in 2003. This paper seeks to expand the discourse on future global health lawmaking by exploring the potential value of non-binding instruments in global health governance, drawing on the case of the 2001 United Nations General Assembly Special Session Declaration of Commitment on HIV/AIDS. In other realms of international concern ranging from the environment to human rights to arms control, non-binding instruments are increasingly used as effective instruments of international cooperation. The experience of the Global AIDS Reporting Mechanism, established pursuant to the Declaration, evidences that, at times, non-binding legal instruments can offer benefits over slower, more rigid binding legal approaches to governance. The global AIDS response has demonstrated that the use of a non-binding instrument can be remarkably effective in galvanizing increasingly deep commitments, action, reporting compliance and ultimately accountability for results. Based on this case, the authors argued that non-binding instruments deserve serious consideration by the international community for the future of global health governance, including in the context of WHO reform. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Intimate partner violence in the Caribbean: State, activist and media responses.

PubMed

DeShong, Halimah A F; Haynes, Tonya

2016-01-01

Violence in the Caribbean is a major public health and criminal justice problem. In some Caribbean countries, women's share of morbidity and mortality due to violence outstrips men's, which demonstrates a reversal in how gender and violence have been typically and globally understood. This morbidity and mortality among women is frequently a consequence of intimate partner violence (IPV). Using qualitative analysis and feminist discourse and narrative analysis on data from Guyana, St. Vincent and the Grenadines and Barbados, the authors of this paper contribute to the growing research on IPV. The central organising questions are how do state, activist and media responses reproduce and/or challenge asymmetrical relations of power and gender, and what does this mean for women's agency in the context of violent relationships. State, activist and media responses reveal how assumptions about gender and IPV contribute to a contradictory context in which women navigate their desired outcomes.

The private sector role in HIV/AIDS in the context of an expanded global response: expenditure trends in five sub-Saharan African countries.

PubMed

Sulzbach, Sara; De, Susna; Wang, Wenjuan

2011-07-01

Global financing for the HIV response has reached unprecedented levels in recent years. Over US$10 billion were mobilized in 2007, an effort credited with saving the lives of millions of people living with HIV (PLHIV). A relatively unexamined aspect of the global HIV response is the role of the private sector in financing HIV/AIDS services. As the nature of the response evolves from emergency relief to long-term sustainability, understanding current and potential contributions from the private sector is critical. This paper examines trends in private sector financing, management and resource consumption related to HIV/AIDS in five sub-Saharan African countries, with a particular emphasis on the effects of recently scaled-up donor funding on private sector contributions. We analysed National Health Accounts HIV/AIDS subaccount data for Kenya, Malawi, Rwanda, Tanzania and Zambia between 2002 and 2006. HIV subaccounts provide comparable data on the flow of HIV/AIDS funding from source to use. Findings indicate that private sector contributions decreased in all countries except Tanzania. With regards to managing HIV/AIDS funds, non-governmental organizations are increasingly controlling the largest share of resources relative to other stakeholders, whereas private for-profit entities are managing fewer HIV/AIDS resources since the donor influx. The majority of HIV/AIDS funds were spent in the public sector, although a considerable amount was spent at private facilities, largely fuelled by out-of-pocket (OOP) payments. On the whole, OOP spending by PLHIV decreased over the 4-year period, with the exception of Malawi, demonstrating that PLHIV have increased access to free or subsidized HIV/AIDS services. Our findings suggest that the influx of donor funding has led to decreased private contributions for HIV/AIDS. The reduction in private sector investment and engagement raises concerns about the sustainability of HIV/AIDS programmes over the long term, particularly in light of current global economic crisis and emerging competing priorities.

Gene Expression Signatures Characterized by Longitudinal Stability and Interindividual Variability Delineate Baseline Phenotypic Groups with Distinct Responses to Immune Stimulation.

PubMed

Scheid, Adam D; Van Keulen, Virginia P; Felts, Sara J; Neier, Steven C; Middha, Sumit; Nair, Asha A; Techentin, Robert W; Gilbert, Barry K; Jen, Jin; Neuhauser, Claudia; Zhang, Yuji; Pease, Larry R

2018-03-01

Human immunity exhibits remarkable heterogeneity among individuals, which engenders variable responses to immune perturbations in human populations. Population studies reveal that, in addition to interindividual heterogeneity, systemic immune signatures display longitudinal stability within individuals, and these signatures may reliably dictate how given individuals respond to immune perturbations. We hypothesize that analyzing relationships among these signatures at the population level may uncover baseline immune phenotypes that correspond with response outcomes to immune stimuli. To test this, we quantified global gene expression in peripheral blood CD4 + cells from healthy individuals at baseline and following CD3/CD28 stimulation at two time points 1 mo apart. Systemic CD4 + cell baseline and poststimulation molecular immune response signatures (MIRS) were defined by identifying genes expressed at levels that were stable between time points within individuals and differential among individuals in each state. Iterative differential gene expression analyses between all possible phenotypic groupings of at least three individuals using the baseline and stimulated MIRS gene sets revealed shared baseline and response phenotypic groupings, indicating the baseline MIRS contained determinants of immune responsiveness. Furthermore, significant numbers of shared phenotype-defining sets of determinants were identified in baseline data across independent healthy cohorts. Combining the cohorts and repeating the analyses resulted in identification of over 6000 baseline immune phenotypic groups, implying that the MIRS concept may be useful in many immune perturbation contexts. These findings demonstrate that patterns in complex gene expression variability can be used to define immune phenotypes and discover determinants of immune responsiveness. Copyright © 2018 by The American Association of Immunologists, Inc.

tranSMART: An Open Source and Community-Driven Informatics and Data Sharing Platform for Clinical and Translational Research.

PubMed

Athey, Brian D; Braxenthaler, Michael; Haas, Magali; Guo, Yike

2013-01-01

tranSMART is an emerging global open source public private partnership community developing a comprehensive informatics-based analysis and data-sharing cloud platform for clinical and translational research. The tranSMART consortium includes pharmaceutical and other companies, not-for-profits, academic entities, patient advocacy groups, and government stakeholders. The tranSMART value proposition relies on the concept that the global community of users, developers, and stakeholders are the best source of innovation for applications and for useful data. Continued development and use of the tranSMART platform will create a means to enable "pre-competitive" data sharing broadly, saving money and, potentially accelerating research translation to cures. Significant transformative effects of tranSMART includes 1) allowing for all its user community to benefit from experts globally, 2) capturing the best of innovation in analytic tools, 3) a growing 'big data' resource, 4) convergent standards, and 5) new informatics-enabled translational science in the pharma, academic, and not-for-profit sectors.

Maximal feeding with active prey-switching: A kill-the-winner functional response and its effect on global diversity and biogeography

NASA Astrophysics Data System (ADS)

Vallina, S. M.; Ward, B. A.; Dutkiewicz, S.; Follows, M. J.

2014-01-01

Predators' switching towards the most abundant prey is a mechanism that stabilizes population dynamics and helps overcome competitive exclusion of species in food webs. Current formulations of active prey-switching, however, display non-maximal feeding in which the predators' total ingestion decays exponentially with the number prey species (i.e. the diet breadth) even though the total prey biomass stays constant. We analyse three previously published multi-species functional responses which have either active switching or maximal feeding, but not both. We identify the cause of this apparent incompatibility and describe a kill-the-winner formulation that combines active switching with maximal feeding. Active switching is shown to be a community response in which some predators become prey-selective and the formulations with maximal or non-maximal feeding are implicitly assuming different food web configurations. Global simulations using a marine ecosystem model with 64 phytoplankton species belonging to 4 major functional groups show that the species richness and biogeography of phytoplankton are very sensitive to the choice of the functional response for grazing. The phytoplankton biogeography reflects the balance between the competitive abilities for nutrient uptake and the degree of apparent competition which occurs indirectly between species that share a common predator species. The phytoplankton diversity significantly increases when active switching is combined with maximal feeding through predator-mediated coexistence.

Locating ethics in data science: responsibility and accountability in global and distributed knowledge production systems

PubMed Central

2016-01-01

The distributed and global nature of data science creates challenges for evaluating the quality, import and potential impact of the data and knowledge claims being produced. This has significant consequences for the management and oversight of responsibilities and accountabilities in data science. In particular, it makes it difficult to determine who is responsible for what output, and how such responsibilities relate to each other; what ‘participation’ means and which accountabilities it involves, with regard to data ownership, donation and sharing as well as data analysis, re-use and authorship; and whether the trust placed on automated tools for data mining and interpretation is warranted (especially as data processing strategies and tools are often developed separately from the situations of data use where ethical concerns typically emerge). To address these challenges, this paper advocates a participative, reflexive management of data practices. Regulatory structures should encourage data scientists to examine the historical lineages and ethical implications of their work at regular intervals. They should also foster awareness of the multitude of skills and perspectives involved in data science, highlighting how each perspective is partial and in need of confrontation with others. This approach has the potential to improve not only the ethical oversight for data science initiatives, but also the quality and reliability of research outputs. This article is part of the themed issue ‘The ethical impact of data science’. PMID:28336799

Locating ethics in data science: responsibility and accountability in global and distributed knowledge production systems.

PubMed

Leonelli, Sabina

2016-12-28

The distributed and global nature of data science creates challenges for evaluating the quality, import and potential impact of the data and knowledge claims being produced. This has significant consequences for the management and oversight of responsibilities and accountabilities in data science. In particular, it makes it difficult to determine who is responsible for what output, and how such responsibilities relate to each other; what 'participation' means and which accountabilities it involves, with regard to data ownership, donation and sharing as well as data analysis, re-use and authorship; and whether the trust placed on automated tools for data mining and interpretation is warranted (especially as data processing strategies and tools are often developed separately from the situations of data use where ethical concerns typically emerge). To address these challenges, this paper advocates a participative, reflexive management of data practices. Regulatory structures should encourage data scientists to examine the historical lineages and ethical implications of their work at regular intervals. They should also foster awareness of the multitude of skills and perspectives involved in data science, highlighting how each perspective is partial and in need of confrontation with others. This approach has the potential to improve not only the ethical oversight for data science initiatives, but also the quality and reliability of research outputs.This article is part of the themed issue 'The ethical impact of data science'. © 2015 The Authors.

Lessons learned from national food fortification projects: experiences from Morocco, Uzbekistan, and Vietnam.

PubMed

Wirth, James P; Laillou, Arnaud; Rohner, Fabian; Northrop-Clewes, Christine A; Macdonald, Barbara; Moench-Pfanner, Regina

2012-12-01

Fortification of staple foods has been repeatedly recommended as an effective approach to reduce micronutrient deficiencies. With the increased number of fortification projects globally, there is a need to share practical lessons learned relating to their implementation and responses to project-related and external challenges. To document the achievements, challenges, lessons learned, and management responses associated with national fortification projects in Morocco, Uzbekistan, and Vietnam. Independent end-of-project evaluations conducted for each project served as the primary data source and contain the history of and project activities undertaken for, each fortification project. Other sources, including national policy documents, project reports from the Global Alliance for Improved Nutrition (GAIN) and other stakeholders, industry assessments, and peer-reviewed articles, were used to document the current responses to challenges and future project plans. All projects had key achievements related to the development of fortification standards and the procurement of equipment for participating industry partners. Mandatory fortification of wheat flour was a key success in Morocco and Uzbekistan. Ensuring the quality of fortified foods was a common challenge experienced across the projects, as were shifts in consumption patterns and market structures. Adjustments were made to the projects' design to address the challenges faced. National fortification projects are dynamic and must be continually modified in response to specific performance issues and broader shifts in market structure and consumption patterns.

International inter-rater agreement in scoring acne severity utilizing cloud-based image sharing of mobile phone photographs.

PubMed

Foolad, Negar; Ornelas, Jennifer N; Clark, Ashley K; Ali, Ifrah; Sharon, Victoria R; Al Mubarak, Luluah; Lopez, Andrés; Alikhan, Ali; Al Dabagh, Bishr; Firooz, Alireza; Awasthi, Smita; Liu, Yu; Li, Chin-Shang; Sivamani, Raja K

2017-09-01

Cloud-based image sharing technology allows facilitated sharing of images. Cloud-based image sharing technology has not been well-studied for acne assessments or treatment preferences, among international evaluators. We evaluated inter-rater variability of acne grading and treatment recommendations among an international group of dermatologists that assessed photographs. This is a prospective, single visit photographic study to assess inter-rater agreement of acne photographs shared through an integrated mobile device, cloud-based, and HIPAA-compliant platform. Inter-rater agreements for global acne assessment and acne lesion counts were evaluated by the Kendall's coefficient of concordance while correlations between treatment recommendations and acne severity were calculated by Spearman's rank correlation coefficient. There was good agreement for the evaluation of inflammatory lesions (KCC = 0.62, P < 0.0001), noninflammatory lesions (KCC = 0.62, P < 0.0001), and the global acne grading system score (KCC = 0.69, P < 0.0001). Topical retinoid, oral antibiotic, and isotretinoin treatment preferences correlated with photographic based acne severity. Our study supports the use of mobile phone based photography and cloud-based image sharing for acne assessment. Cloud-based sharing may facilitate acne care and research among international collaborators. © 2017 The International Society of Dermatology.

Ocean Data Interoperability Platform: developing a common global framework for marine data management

NASA Astrophysics Data System (ADS)

Glaves, Helen; Schaap, Dick

2017-04-01

In recent years there has been a paradigm shift in marine research moving from the traditional discipline based methodology employed at the national level by one or more organizations, to a multidisciplinary, ecosystem level approach conducted on an international scale. This increasingly holistic approach to marine research is in part being driven by policy and legislation. For example, the European Commission's Blue Growth strategy promotes sustainable growth in the marine environment including the development of sea-basin strategies (European Commission 2014). As well as this policy driven shift to ecosystem level marine research there are also scientific and economic drivers for a basin level approach. Marine monitoring is essential for assessing the health of an ecosystem and determining the impacts of specific factors and activities on it. The availability of large volumes of good quality data is fundamental to this increasingly holistic approach to ocean research but there are significant barriers to its re-use. These are due to the heterogeneity of the data resulting from having been collected by many organizations around the globe using a variety of sensors mounted on a range of different platforms. The data is then delivered and archived in a range of formats, using various spatial coordinate systems and aligned with different standards. This heterogeneity coupled with organizational and national policies on data sharing make access and re-use of marine data problematic. In response to the need for greater sharing of marine data a number of e-infrastructures have been developed but these have different levels of granularity with the majority having been developed at the regional level to address specific requirements for data e.g. SeaDataNet in Europe, the Australian Ocean Data Network (AODN). These data infrastructures are also frequently aligned with the priorities of the local funding agencies and have been created in isolation from those developed elsewhere. To add a further layer of complexity there are also global initiatives providing marine data infrastructures e.g. IOC-IODE, POGO as well as those with a wider remit which includes environmental data e.g. GEOSS, COPERNICUS etc. Ecosystem level marine research requires a common framework for marine data management that supports the sharing of data across these regional and global data systems, and provides the user with access to the data available from these services via a single point of access. This framework must be based on existing data systems and established by developing interoperability between them. The Ocean Data and Interoperability Platform (ODIP/ODIP II) project brings together those organisations responsible for maintaining selected regional data infrastructures along with other relevant experts in order to identify the common standards and best practice necessary to underpin this framework, and to evaluate the differences and commonalties between the regional data infrastructures in order to establish interoperability between them for the purposes of data sharing. This coordinated approach is being demonstrated and validated through the development of a series of prototype interoperability solutions that demonstrate the mechanisms and standards necessary to facilitate the sharing of marine data across these existing data infrastructures.

Haemophilus influenzae Disease (Including Hib) Symptoms

MedlinePlus

... Links Global Hib Vaccination Hib Vaccination Meningitis Pneumonia Sepsis Signs and Symptoms Recommend on Facebook Tweet Share ... Links Global Hib Vaccination Hib Vaccination Meningitis Pneumonia Sepsis File Formats Help: How do I view different ...

Understanding global health and development partnerships: Perspectives from African and global health system professionals.

PubMed

Barnes, Amy; Brown, Garrett W; Harman, Sophie

2016-06-01

Partnership is a key idea in current debates about global health and development assistance, yet little is known about what partnership means to those who are responsible for operationalising it or how it is experienced in practice. This is particularly the case in the context of African health systems. This paper explores how health professionals working in global health hubs and the health systems of South Africa, Tanzania and Zambia understand and experience partnership. Drawing on semi-structured interviews with 101 professionals based in each country, Washington DC and Geneva between October 2012 and June 2013, the paper makes four key arguments. First, partnership has a legitimating function in global health policy processes for international development institutions, government agencies and civil society organisations alike. Second, the practice of partnership generates idiosyncratic and complicated relationships that health professionals have to manage and navigate, often informally. Third, partnership is shaped by historical legacies, critical events, and independent consultants. Fourth, despite being an accepted part of global health policy, there is little shared understanding of what good partnership is meant to include or resemble in practice. Knowing more about the specific socio-cultural and political dynamics of partnership in different health system contexts is critical to equip health professionals with the skills to build the informal relations that are essential to effective partnership engagement. Copyright © 2016 Elsevier Ltd. All rights reserved.

Rights and Responsibilities of Tuberculosis Patients, and the Global Fund: A Qualitative Study.

PubMed

Atif, Muhammad; Javaid, Sareema; Farooqui, Maryam; Sarwar, Muhammad Rehan

2016-01-01

Implementation of the Charter to protect patients' rights is an important criterion to achieve patient-centered approach and receive financial support from the Global Fund. Our study aims to explore the knowledge of tuberculosis (TB) patients about their rights and responsibilities at the Chest Disease Unit of the Bahawal Victoria Hospital, Bahawalpur, Pakistan. This was a qualitative study. The data from purposefully selected TB patients was collected by in-depth interviews. Eligibility criteria included confirmed diagnosis of TB and enrollment in the TB program. A pilot tested interview protocol was based upon the objectives of the study, and was used uniformly in each interview to maintain the consistency. The sample size was limited by applying the saturation criteria. All interviews were audiotaped and transcribed verbatim. Inductive thematic content analysis was applied to analyze the data and draw conclusions. Out of the total 16 patients, four were female, and seven were illiterate. Eight patients were known cases of multi-drug resistant TB. Analysis of the data yielded seven themes; tuberculosis care services, moral support and stigmatization, dignity and privacy, complaints, fear of losing job, information sharing and compliance to the treatment plan, and contribution to eradicate TB. First five represented the rights section while latter two were related to the responsibilities section of the Charter. Discriminatory access to TB care services and the right to privacy were two major concerns identified in this study. However, the respondents recognized their responsibilities as a TB patient. To ensure uninterrupted investment from the Global Fund, there is a need to implement fair TB care policies which support human rights-based approach.

Rights and Responsibilities of Tuberculosis Patients, and the Global Fund: A Qualitative Study

PubMed Central

Atif, Muhammad; Javaid, Sareema; Farooqui, Maryam; Sarwar, Muhammad Rehan

2016-01-01

Background Implementation of the Charter to protect patients’ rights is an important criterion to achieve patient-centered approach and receive financial support from the Global Fund. Our study aims to explore the knowledge of tuberculosis (TB) patients about their rights and responsibilities at the Chest Disease Unit of the Bahawal Victoria Hospital, Bahawalpur, Pakistan. Methods This was a qualitative study. The data from purposefully selected TB patients was collected by in-depth interviews. Eligibility criteria included confirmed diagnosis of TB and enrollment in the TB program. A pilot tested interview protocol was based upon the objectives of the study, and was used uniformly in each interview to maintain the consistency. The sample size was limited by applying the saturation criteria. All interviews were audiotaped and transcribed verbatim. Inductive thematic content analysis was applied to analyze the data and draw conclusions. Results Out of the total 16 patients, four were female, and seven were illiterate. Eight patients were known cases of multi-drug resistant TB. Analysis of the data yielded seven themes; tuberculosis care services, moral support and stigmatization, dignity and privacy, complaints, fear of losing job, information sharing and compliance to the treatment plan, and contribution to eradicate TB. First five represented the rights section while latter two were related to the responsibilities section of the Charter. Conclusion Discriminatory access to TB care services and the right to privacy were two major concerns identified in this study. However, the respondents recognized their responsibilities as a TB patient. To ensure uninterrupted investment from the Global Fund, there is a need to implement fair TB care policies which support human rights-based approach. PMID:26998830

Individual responsibility as ground for priority setting in shared decision-making.

PubMed

Sandman, Lars; Gustavsson, Erik; Munthe, Christian

2016-10-01

Given healthcare resource constraints, voices are being raised to hold patients responsible for their health choices. In parallel, there is a growing trend towards shared decision-making, aiming to empower patients and give them more control over healthcare decisions. More power and control over decisions is usually taken to mean more responsibility for them. The trend of shared decision-making would therefore seem to strengthen the case for invoking individual responsibility in the healthcare priority setting. To analyse whether the implementation of shared decision-making would strengthen the argument for invoking individual responsibility in the healthcare priority setting using normative analysis. Shared decision-making does not constitute an independent argument in favour of employing individual responsibility since these notions rest on different underlying values. However, if a health system employs shared decision-making, individual responsibility may be used to limit resource implications of accommodating patient preferences outside professional standards and goals. If a healthcare system employs individual responsibility, high level dynamic shared decision-making implying a joint deliberation resulting in a decision where both parties are willing to revise initial standpoints may disarm common objections to the applicability of individual responsibility by virtue of making patients more likely to exercise adequate control of their own actions. However, if communication strategies applied in the shared decision-making are misaligned to the patient's initial capacities, arguments against individual responsibility might, on the other hand, gain strength. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

78 FR 16445 - Shared Responsibility for Employers Regarding Health Coverage; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... respect to the shared responsibility for employers regarding employee health coverage. FOR FURTHER...-BL33 Shared Responsibility for Employers Regarding Health Coverage; Correction AGENCY: Internal Revenue... the paragraph heading ``4. Employees Rehired After Termination of Employment or Resuming Service After...

Energy, the hinge of history

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loraine, J.A.

1981-03-01

The failure of nations to share the Earth's limited resources may make the decade of the 1980s one of conflict and possible disaster. A solution to international nuclear control is barred by our inability to separate peaceful and military applications. The only progress is seen in a slowing of global population growth and demographic shifts to an older population, but an aging population will demand shifts in socio-economic and medical resources at the expense of vision and boldness. Electronic innovation will, in addition to its advantages, cause deindustrialization and a reevaluation of the work ethic. The psychological consequences of unemploymentmore » and excessive urbanization will be strongest in the developing countries. Energy will be the key factor in global responses during the 1980s. The energy policies of the US, Soviet Union, and Western Europe will be crucial during this decade as impersonal forces push the world toward disaster. 21 references. (DCK)« less

Irrational Delay Revisited: Examining Five Procrastination Scales in a Global Sample

PubMed Central

Svartdal, Frode; Steel, Piers

2017-01-01

Scales attempting to measure procrastination focus on different facets of the phenomenon, yet they share a common understanding of procrastination as an unnecessary, unwanted, and disadvantageous delay. The present paper examines in a global sample (N = 4,169) five different procrastination scales – Decisional Procrastination Scale (DPS), Irrational Procrastination Scale (IPS), Pure Procrastination Scale (PPS), Adult Inventory of Procrastination Scale (AIP), and General Procrastination Scale (GPS), focusing on factor structures and item functioning using Confirmatory Factor Analysis and Item Response Theory. The results indicated that The PPS (12 items selected from DPS, AIP, and GPS) measures different facets of procrastination even better than the three scales it is based on. An even shorter version of the PPS (5 items focusing on irrational delay), corresponds well to the nine-item IPS. Both scales demonstrate good psychometric properties and appear to be superior measures of core procrastination attributes than alternative procrastination scales. PMID:29163302

Irrational Delay Revisited: Examining Five Procrastination Scales in a Global Sample.

PubMed

Svartdal, Frode; Steel, Piers

2017-01-01

Scales attempting to measure procrastination focus on different facets of the phenomenon, yet they share a common understanding of procrastination as an unnecessary, unwanted, and disadvantageous delay. The present paper examines in a global sample ( N = 4,169) five different procrastination scales - Decisional Procrastination Scale (DPS), Irrational Procrastination Scale (IPS), Pure Procrastination Scale (PPS), Adult Inventory of Procrastination Scale (AIP), and General Procrastination Scale (GPS), focusing on factor structures and item functioning using Confirmatory Factor Analysis and Item Response Theory. The results indicated that The PPS (12 items selected from DPS, AIP, and GPS) measures different facets of procrastination even better than the three scales it is based on. An even shorter version of the PPS (5 items focusing on irrational delay), corresponds well to the nine-item IPS. Both scales demonstrate good psychometric properties and appear to be superior measures of core procrastination attributes than alternative procrastination scales.

Science, Ethics and the Climate Responsibilities of Industrial Carbon Producers

NASA Astrophysics Data System (ADS)

Frumhoff, P. C.

2014-12-01

The question of responsibility for climate change lies at the heart of societal debate over actions to curb greenhouse gas emissions and prepare for now unavoidable climate impacts. The UN Framework Convention on Climate Change established the principle of "common but differentiated responsibilities" among nations, signaling the recognition that industrialized nations who had produced the lion's share of historic emissions bore particular responsibility for avoiding dangerous interference with the climate system. But climate responsibilities can be distributed in other ways as well. This talk focuses on the scientific, historical and ethical basis for considering the climate responsibilities of the major fossil energy companies that have produced and marketed the coal, oil and natural gas whose use largely drives global warming, often while investing in efforts to discredit the scientific evidence and prevent policies that would encourage a transition to low-carbon energy. Earth scientists and scientific societies who rely on financial support from these companies have an opportunity to consider what ethical stance they might take to align their research, scientific understanding and values.

Global Competency Education Catches Fire at a Rural University

ERIC Educational Resources Information Center

Talbot, Patricia A.; Gustafson, Glenna; Mistele, Jean

2017-01-01

World-ready learners require world-ready educators. One group of inspiring teacher educators share how they ignited a fire of awareness around the importance of global competency education at a small, rural teacher college.

Cosmos as Resonant Harmonies ˜ Singing International Year of Astronomy, 2009 ˜ the cultural significance of our new encounter with the universe

NASA Astrophysics Data System (ADS)

Perkins, Kala

2008-04-01

UN Int'l Year of Astronomy (IYA), 2009 will celebrate 400 yrs. since Galileo's quests. Bringing the unifying dimensions of cosmos to the global community, sharing the wonder and calling forth the unparalleled ability of astronomy to dwarf our disputations, open our hearts to Einstein's ``cosmological feeling'' and propel us on this collective global adventure, is the nexus of intent. IYA is a global effort to bring the human creative endeavor into harmonic interplay with the universe that is singing us. We are cosmos creating ourselves, taking the reigns of our inherent potency and wondering how law and logos emerge into the entangled formulas and phenomenology of cosmic reason and reality. How is our cosmic encounter affecting our socio-cultural identity and psychology? What harmonies are emerging in researchers in response to our penetration into cosmic etudes of black holes, large-scale flows and stellar dynamics? We are learning to creatively resonate with the universe. Some excellent ideas being brewed for communicating the cosmos to students and the public will be explored.

Germanium Isotopes - the Global Budget and Paleoceanographic Potential

NASA Astrophysics Data System (ADS)

Baronas, J. J.; Hammond, D. E.; Rouxel, O. J.

2017-12-01

The distribution of element isotope ratios in rocks, sediments, rivers, and seawater can provide key insights about the operation and coupling of various biogeochemical cycles that are directly or indirectly responsible for the climate and habitability of the Earth surface environment. Germanium (Ge) is a trace element that shares many chemical similarities with silicon (Si), in addition to some siderophilic, chalcophilic, and organophilic properties. As a result, Ge stable isotope ratios (δ74Ge) and Ge/Si ratios can be used to trace various biogeochemical processes. These include silicate rock weathering, which modulates atmospheric pCO2 and supplies nutrients to ecosystems, biogenic silica formation, which is coupled to ocean productivity, and marine sediment diagenesis, which ultimately controls the removal of material from the Earth's surface. I will present an overview of my dissertation research concerning the global Ge isotope cycle, with insights into Ge isotope fractionation during secondary mineral precipitation during weathering on continents and during authigenesis in marine sediments. I will also discuss the potential for the δ74Ge sedimentary record to be used as a paleoceanographic proxy, given the constraints on the global Ge isotope budget.

Seasonal and interannual variations of atmospheric CO2 and climate

USGS Publications Warehouse

Dettinger, M.D.; Ghil, M.

1998-01-01

Interannual variations of atmospheric CO2 concentrations at Mauna Loa are almost masked by the seasonal cycle and a strong trend; at the South Pole, the seasonal cycle is small and is almost lost in the trend and interannual variations. Singular-spectrum analysis (SSA) issued here to isolate and reconstruct interannual signals at both sites and to visualize recent decadal changes in the amplitude and phase of the seasonal cycle. Analysis of the Mauna Loa CO2 series illustrates a hastening of the CO2 seasonal cycle, a close temporal relation between Northern Hemisphere (NH) mean temperature trends and the amplitude of the seasonal CO2 cycle, and tentative ties between the latter and seasonality changes in temperature over the NH continents. Variations of the seasonal CO2 cycle at the South Pole differ from those at Mauna Loa: it is phase changes of the seasonal cycle at the South Pole, rather than amplitude changes, that parallel hemispheric and global temperature trends. The seasonal CO2 cycles exhibit earlier occurrences of the seasons by 7 days at Mauna Loa and 18 days at the South Pole. Interannual CO2 variations are shared at the two locations, appear to respond to tropical processes, and can be decomposed mostly into two periodicities, around (3 years)-1 and (4 years)-1, respectively. Joint SSA analyses of CO2 concentrations and tropical climate indices isolate a shared mode with a quasi-triennial (QT) period in which the CO2 and sea-surface temperature (SST) participation are in phase opposition. The other shared mode has a quasi-quadrennial (QQ) period and CO2 variations are in phase with the corresponding tropical SST variations throughout the tropics. Together these interannual modes exhibit a mean lag between tropical SSTs and CO2 variations of about 6-8 months, with SST leading. Analysis of the QT and QQ signals in global gridded SSTs, joint SSA of CO2 and ??13C isotopic ratios, and SSA of CO2 and NH-land temperatures indicate that the QT variations in CO2 mostly reflect upwelling variations in the eastern tropical Pacific. QQ variations are dominated by the CO2 signature of terrestrial-ecosystem response to global QQ climate variations. Climate variations associated with these two interannual components of tropical variability have very different effects on global climate and, especially, on terrestrial ecosystems and the carbon cycle.

The Contribution of Agriculture, Forestry and other Land Use activities to Global Warming, 1990-2012.

PubMed

Tubiello, Francesco N; Salvatore, Mirella; Ferrara, Alessandro F; House, Jo; Federici, Sandro; Rossi, Simone; Biancalani, Riccardo; Condor Golec, Rocio D; Jacobs, Heather; Flammini, Alessandro; Prosperi, Paolo; Cardenas-Galindo, Paola; Schmidhuber, Josef; Sanz Sanchez, Maria J; Srivastava, Nalin; Smith, Pete

2015-01-10

We refine the information available through the IPCC AR5 with regard to recent trends in global GHG emissions from agriculture, forestry and other land uses (AFOLU), including global emission updates to 2012. Using all three available AFOLU datasets employed for analysis in the IPCC AR5, rather than just one as done in the IPCC AR5 WGIII Summary for Policy Makers, our analyses point to a down-revision of global AFOLU shares of total anthropogenic emissions, while providing important additional information on subsectoral trends. Our findings confirm that the share of AFOLU emissions to the anthropogenic total declined over time. They indicate a decadal average of 28.7 ± 1.5% in the 1990s and 23.6 ± 2.1% in the 2000s and an annual value of 21.2 ± 1.5% in 2010. The IPCC AR5 had indicated a 24% share in 2010. In contrast to previous decades, when emissions from land use (land use, land use change and forestry, including deforestation) were significantly larger than those from agriculture (crop and livestock production), in 2010 agriculture was the larger component, contributing 11.2 ± 0.4% of total GHG emissions, compared to 10.0 ± 1.2% of the land use sector. Deforestation was responsible for only 8% of total anthropogenic emissions in 2010, compared to 12% in the 1990s. Since 2010, the last year assessed by the IPCC AR5, new FAO estimates indicate that land use emissions have remained stable, at about 4.8 Gt CO 2 eq yr -1 in 2012. Emissions minus removals have also remained stable, at 3.2 Gt CO 2 eq yr -1 in 2012. By contrast, agriculture emissions have continued to grow, at roughly 1% annually, and remained larger than the land use sector, reaching 5.4 Gt CO 2 eq yr -1 in 2012. These results are useful to further inform the current climate policy debate on land use, suggesting that more efforts and resources should be directed to further explore options for mitigation in agriculture, much in line with the large efforts devoted to REDD+ in the past decade. © 2015 John Wiley & Sons Ltd.

Globalization, English Language Teaching and Turkey

ERIC Educational Resources Information Center

Altan, Mustafa Zülküf

2017-01-01

Globalization as a concept has been used both positively and negatively by many different people and in many different situations. Depending on the point of view, all definitions on globalization state that it has the power of creating a world without boundaries where people communicate, share, and do business with the help of information,…

75 FR 7637 - iShares Trust, et al.; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-22

... ETFs.\\5\\ \\4\\ See, e.g., South Asia Portfolio, SEC No-Action Letter (Mar. 12, 1997). \\5\\ Barclays Global... Global Fund Advisors, et al., Investment Company Act Release No. 26175 (Sep. 8, 2003), and Barclays Global Fund Advisors, et al., Investment Company Act Release No. 27417 (Jun. 23, 2006) (as amended, the...

Sociological Implications of English as an International Language in Music Education

ERIC Educational Resources Information Center

Kertz-Welzel, Alexandra

2016-01-01

Internationalization and globalization have created a global music education community which is not only linked by similar ideas, but also shares a common language. English functions as a global language and facilitates the international discourse in music education. While it is good to have a common language supporting international dialogue, it…

Developing Global Leaders: Building Effective Global- Intercultural Collaborative Online Learning Environments

ERIC Educational Resources Information Center

Ivy, Karen Lynne-Daniels

2017-01-01

This paper shares the findings of a study conducted on a virtual inter-cultural global leadership development learning project. Mixed Methods analysis techniques were used to examine the interviews of U.S. and Uganda youth project participants. The study, based on cultural and social constructivist learning theories, investigated the effects of…

Epilepsy Research in India: A Scientometric Analysis of Publications Output during 2002-11.

PubMed

Gupta, Brij M; Bala, Adarsh

2013-04-01

This study analyses the research output of India in epilepsy research during 2002-11 on several parameters including the growth, rank and global publications share, citation impact, share of international collaborative papers, contribution of major collaborative partner countries, contribution of various subject-fields, contribution and impact of most productive institutions and authors, media of communication and characteristics of high cited papers. The Scopus Citation Database has been used to retrieve the data for 10 years (2002-11) by searching the keywords "epilepsy research" in the combined Title, Abstract and Keywords fields. Among the top 20 most productive countries in epilepsy research, India ranks at 11(th) position (with 1550 papers) with a global publication share of 2.88% and an annual average publication growth rate of 15.31% during 2002-11. Its global publication share has increased over the years, rising from 2.06% in 2002 to 4.65% during 2011. Its citation impact per paper was 2.77 during 2002-11, which decreased from 3.48 during 2002-06 to 2.41 during 2007-11. Its international collaborative publications share was 12.32% during 2002-11, which decreased from 12.45% during 2002-06 to 12.26% during 2007-11. Concludes that India needs to increase both the quantity and quality of research and also the need to share research data and stimulate national and international collaborative research, which will increase both the quantity and quality of research in epilepsy. There is a need to develop a national program on epilepsy as a part of national health plan, besides suggesting the funding agencies to establish a more ambitious funding program into the causes, prevention, cure and care of epilepsy. There is a need to build capacity at all levels of human resources for the management of epilepsy.

Knowledge networks for global public health.

PubMed

Natividad, Maria Dulce F; Fiereck, Kirk J; Parker, Richard

2012-01-01

The challenges posed by a globalised world have made it imperative for society to search for solutions to emerging issues and to develop new ways of looking at old problems. Current discussions about global public health demand a shift in paradigms and the strategic positioning of public health within broader policy discussions that will enable it to influence political and action agendas. Critical to responding to these challenges is the generation, transmission and dissemination of new knowledge to create value. Recognising the cutting-edge role of knowledge, as a new form of capital that drives innovation and transforms society, the formation of knowledge networks is viewed as a strategy for developing a shared intellectual, conceptual and ethical infrastructure for the field of global public health. These knowledge networks are envisioned as a vehicle for sharing diverse perspectives, encouraging debate and sustaining alternative ways of thinking about and responding to the challenges that confront global public health today and in the future.

Application Architecture of Avian Influenza Research Collaboration Network in Korea e-Science

NASA Astrophysics Data System (ADS)

Choi, Hoon; Lee, Junehawk

In the pursuit of globalization of the AI e-Science environment, KISTI is fostering to extend the AI research community to the AI research institutes of neighboring countries and to share the AI e-Science environment with them in the near future. In this paper we introduce the application architecture of AI research collaboration network (AIRCoN). AIRCoN is a global e-Science environment for AI research conducted by KISTI. It consists of AI virus sequence information sharing system for sufficing data requirement of research community, integrated analysis environment for analyzing the mutation pattern of AI viruses and their risks, epidemic modeling and simulation environment for establishing national effective readiness strategy against AI pandemics, and knowledge portal for sharing expertise of epidemic study and unpublished research results with community members.

World Water Online (WWO) Status and Prospects

NASA Astrophysics Data System (ADS)

Arctur, David; Maidment, David

2013-04-01

Water resources, weather, and natural disasters are not constrained by local, regional or national boundaries. Effective research, planning, and response to major events call for improved coordination and data sharing among many organizations, which requires improved interoperability among the organizations' diverse information systems. Just for the historical time series records of surface freshwater resources data compiled by U.S. national agencies, there are over 23 million distributed datasets available today. Cataloguing and searching efficiently for specific content from this many datasets presents a challenge to current standards and practices for digital geospatial catalogues. This presentation summarizes a new global platform for water resource information discovery and sharing, that provides coordinated, interactive access to water resource metadata for the complete holdings of the Global Runoff Data Centre, the U.S. Geological Survey, and other primary sources. In cases where the data holdings are not restricted by national policy, this interface enables direct access to the water resource data, hydrographs, and other derived products. This capability represents a framework in which any number of other services can be integrated in user-accessible workflows, such as to perform watershed delineation from any point on the stream network. World Water Online web services for mapping and metadata have been registered with GEOSS. In addition to summarizing the architecture and capabilities of World Water Online, future plans for integration with GEOSS and EarthCube will be presented.

Raising Virtual Laboratories in Australia onto global platforms

NASA Astrophysics Data System (ADS)

Wyborn, L. A.; Barker, M.; Fraser, R.; Evans, B. J. K.; Moloney, G.; Proctor, R.; Moise, A. F.; Hamish, H.

2016-12-01

Across the globe, Virtual Laboratories (VLs), Science Gateways (SGs), and Virtual Research Environments (VREs) are being developed that enable users who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, etc. Outcomes range from enabling `long tail' researchers to more easily access specific data collections, to facilitating complex workflows on powerful supercomputers. In Australia, government funding has facilitated the development of a range of VLs through the National eResearch Collaborative Tools and Resources (NeCTAR) program. The VLs provide highly collaborative, research-domain oriented, integrated software infrastructures that meet user community needs. Twelve VLs have been funded since 2012, including the Virtual Geophysics Laboratory (VGL); Virtual Hazards, Impact and Risk Laboratory (VHIRL); Climate and Weather Science Laboratory (CWSLab); Marine Virtual Laboratory (MarVL); and Biodiversity and Climate Change Virtual Laboratory (BCCVL). These VLs share similar technical challenges, with common issues emerging on integration of tools, applications and access data collections via both cloud-based environments and other distributed resources. While each VL began with a focus on a specific research domain, communities of practice have now formed across the VLs around common issues, and facilitate identification of best practice case studies, and new standards. As a result, tools are now being shared where the VLs access data via data services using international standards such as ISO, OGC, W3C. The sharing of these approaches is starting to facilitate re-usability of infrastructure and is a step towards supporting interdisciplinary research. Whilst the focus of the VLs are Australia-centric, by using standards, these environments are able to be extended to analysis on other international datasets. Many VL datasets are subsets of global datasets and so extension to global is a small (and often requested) step. Similarly, most of the tools, software, and other technologies could be shared across infrastructures globally. Therefore, it is now time to better connect the Australian VLs with similar initiatives elsewhere to create international platforms that can contribute to global research challenges.

Generating community-built tools for data sharing and analysis in environmental networks

USGS Publications Warehouse

Read, Jordan S.; Gries, Corinna; Read, Emily K.; Klug, Jennifer; Hanson, Paul C.; Hipsey, Matthew R.; Jennings, Eleanor; O'Reilley, Catherine; Winslow, Luke A.; Pierson, Don; McBride, Christopher G.; Hamilton, David

2016-01-01

Rapid data growth in many environmental sectors has necessitated tools to manage and analyze these data. The development of tools often lags behind the proliferation of data, however, which may slow exploratory opportunities and scientific progress. The Global Lake Ecological Observatory Network (GLEON) collaborative model supports an efficient and comprehensive data–analysis–insight life cycle, including implementations of data quality control checks, statistical calculations/derivations, models, and data visualizations. These tools are community-built and openly shared. We discuss the network structure that enables tool development and a culture of sharing, leading to optimized output from limited resources. Specifically, data sharing and a flat collaborative structure encourage the development of tools that enable scientific insights from these data. Here we provide a cross-section of scientific advances derived from global-scale analyses in GLEON. We document enhancements to science capabilities made possible by the development of analytical tools and highlight opportunities to expand this framework to benefit other environmental networks.

New leaders in dentistry: dental students.

PubMed

Hammer, Dan

2010-01-01

Leadership opportunities for dental students have opened dramatically in recent decades because of the humanistic approach to education that shares responsibility for learning between students and faculty and that values mutual respect. Technology has also had an effect because it creates instant access and global communities. This new student leadership is most apparent in the American Student Dental Association (ASDA), which recently developed a White Paper on ethics, assisted in the establishment of Student Professionalism and Ethics Clubs at schools, and is developing a policy on unsupervised dental care. Students are also demonstrating leadership in research; in dual degrees that enhance teaching and policy; and in community service and outreach.

Shared and unique responses of plants to multiple individual stresses and stress combinations: physiological and molecular mechanisms

PubMed Central

Pandey, Prachi; Ramegowda, Venkategowda; Senthil-Kumar, Muthappa

2015-01-01

In field conditions, plants are often simultaneously exposed to multiple biotic and abiotic stresses resulting in substantial yield loss. Plants have evolved various physiological and molecular adaptations to protect themselves under stress combinations. Emerging evidences suggest that plant responses to a combination of stresses are unique from individual stress responses. In addition, plants exhibit shared responses which are common to individual stresses and stress combination. In this review, we provide an update on the current understanding of both unique and shared responses. Specific focus of this review is on heat–drought stress as a major abiotic stress combination and, drought–pathogen and heat–pathogen as examples of abiotic–biotic stress combinations. We also comprehend the current understanding of molecular mechanisms of cross talk in relation to shared and unique molecular responses for plant survival under stress combinations. Thus, the knowledge of shared responses of plants from individual stress studies and stress combinations can be utilized to develop varieties with broad spectrum stress tolerance. PMID:26442037

Governance of global health research consortia: Sharing sovereignty and resources within Future Health Systems.

PubMed

Pratt, Bridget; Hyder, Adnan A

2017-02-01

Global health research partnerships are increasingly taking the form of consortia that conduct programs of research in low and middle-income countries (LMICs). An ethical framework has been developed that describes how the governance of consortia comprised of institutions from high-income countries and LMICs should be structured to promote health equity. It encompasses initial guidance for sharing sovereignty in consortia decision-making and sharing consortia resources. This paper describes a first effort to examine whether and how consortia can uphold that guidance. Case study research was undertaken with the Future Health Systems consortium, performs research to improve health service delivery for the poor in Bangladesh, China, India, and Uganda. Data were thematically analysed and revealed that proposed ethical requirements for sharing sovereignty and sharing resources are largely upheld by Future Health Systems. Facilitating factors included having a decentralised governance model, LMIC partners with good research capacity, and firm budgets. Higher labour costs in the US and UK and the funder's policy of allocating funds to consortia on a reimbursement basis prevented full alignment with guidance on sharing resources. The lessons described in this paper can assist other consortia to more systematically link their governance policy and practice to the promotion of health equity. Copyright © 2016 Elsevier Ltd. All rights reserved.

Multivoxel patterns in face-sensitive temporal regions reveal an encoding schema based on detecting life in a face.

PubMed

Looser, Christine E; Guntupalli, Jyothi S; Wheatley, Thalia

2013-10-01

More than a decade of research has demonstrated that faces evoke prioritized processing in a 'core face network' of three brain regions. However, whether these regions prioritize the detection of global facial form (shared by humans and mannequins) or the detection of life in a face has remained unclear. Here, we dissociate form-based and animacy-based encoding of faces by using animate and inanimate faces with human form (humans, mannequins) and dog form (real dogs, toy dogs). We used multivariate pattern analysis of BOLD responses to uncover the representational similarity space for each area in the core face network. Here, we show that only responses in the inferior occipital gyrus are organized by global facial form alone (human vs dog) while animacy becomes an additional organizational priority in later face-processing regions: the lateral fusiform gyri (latFG) and right superior temporal sulcus. Additionally, patterns evoked by human faces were maximally distinct from all other face categories in the latFG and parts of the extended face perception system. These results suggest that once a face configuration is perceived, faces are further scrutinized for whether the face is alive and worthy of social cognitive resources.

Perceptions, knowledge, and commitment of clinical staff to shared governance.

PubMed

Frith, Karen; Montgomery, Meryl

2006-01-01

The perceptions, knowledge, and commitment of clinical staff to shared governance were explored in a nonexperimental, survey research design, wherein preimplementation responses were compared to postimplementation responses. Using a nonprobability sampling method, all clinical staff members had the opportunity to respond to the Shared Governance Survey at the preimplementation and the 1-year postimplementation period. Thirty-eight clinical areas, including inpatient and outpatient areas, were included in the study. Both surveys contained a short demographic section and the Shared Governance Survey adapted from Minors et al. Results showed a decrease in perception and knowledge of shared governance between the 2 survey periods. This pattern was attributed to the idealism of shared governance in the preimplementation period compared to the reality of implementing shared governance. Interestingly, commitment to shared governance increased during this same time. When the sample was divided into groups, participants in shared governance had significantly higher scores on perception and knowledge of shared governance than did nonparticipants. Overall, participants and nonparticipants were committed to shared governance. The results of the survey indicated that clinical staff members recognized shared governance as a process, not a project, and that it takes time to share responsibility, accountability, and authority for nursing practice.

Measuring disability: a systematic review of the validity and reliability of the Global Activity Limitations Indicator (GALI).

PubMed

Van Oyen, Herman; Bogaert, Petronille; Yokota, Renata T C; Berger, Nicolas

2018-01-01

GALI or Global Activity Limitation Indicator is a global survey instrument measuring participation restriction. GALI is the measure underlying the European indicator Healthy Life Years (HLY). Gali has a substantial policy use within the EU and its Member States. The objective of current paper is to bring together what is known from published manuscripts on the validity and the reliability of GALI. Following the PRISMA guidelines, two search strategies (PUBMED, Google Scholar) were combined to identify manuscripts published in English with publication date 2000 or beyond. Articles were classified as reliability studies, concurrent or predictive validity studies, in national or international populations. Four cross-sectional studies (of which 2 international) studied how GALI relates to other health measures (concurrent validity). A dose-response effect by GALI severity level on the association with the other health status measures was observed in the national studies. The 2 international studies (SHARE, EHIS) concluded that the odds of reporting participation restriction was higher in subjects with self-reported or observed functional limitations. In SHARE, the size of the Odds Ratio's (ORs) in the different countries was homogeneous, while in EHIS the size of the ORs varied more strongly. For the predictive validity, subjects were followed over time (4 studies of which one international). GALI proved, both in national and international data, to be a consistent predictor of future health outcomes both in terms of mortality and health care expenditure. As predictors of mortality, the two distinct health concepts, self-rated health and GALI, acted independently and complementary of each other. The one reliability study identified reported a sufficient reliability of GALI. GALI as inclusive one question instrument fits all conceptual characteristics specified for a global measure on participation restriction. In none of the studies, included in the review, there was evidence of a failing validity. The review shows that GALI has a good and sufficient concurrent and predictive validity, and reliability.

An Approach and Framework to Synchronize Joint Exercises and Training with Military Operations

DTIC Science & Technology

2014-06-06

13. SUPPLEMENTARY NOTES 14. ABSTRACT In this dynamic, complex, and uncertain global environment, supporting and conducting joint military...achieved by leveraging a globally networked approach and an integrated framework that shares resources and coordinates activities. A recommended...Intentionally left blank ABSTRACT In this dynamic, complex, and uncertain global environment, supporting and conducting joint military

On the different "worlds" of intra-organizational knowledge management: Understanding idiosyncratic variation in MNC cross-site knowledge-sharing practices.

PubMed

Kasper, Helmut; Lehrer, Mark; Mühlbacher, Jürgen; Müller, Barbara

2013-02-01

This qualitative field study investigated cross-site knowledge sharing in a small sample of multinational corporations in three different MNC business contexts (global, multidomestic, transnational). The results disclose heterogeneous "worlds" of MNC knowledge sharing, ultimately raising the question as to whether the whole concept of MNC knowledge sharing covers a sufficiently unitary phenomenon to be meaningful. We derive a non-exhaustive typology of MNC knowledge-sharing practices: self-organizing knowledge sharing, technocratic knowledge sharing, and best practice knowledge sharing. Despite its limitations, this typology helps to elucidate a number of issues, including the latent conflict between two disparate theories of MNC knowledge sharing, namely "sender-receiver" and "social learning" theories (Noorderhaven & Harzing, 2009). More generally, we develop the term "knowledge contextualization" to highlight the way that firm-specific organizational features pre-define which knowledge is considered to be of special relevance for intra-organizational sharing.

Coping with Prescription Drug Cost Sharing: Knowledge, Adherence, and Financial Burden

PubMed Central

Reed, Mary; Brand, Richard; Newhouse, Joseph P; Selby, Joe V; Hsu, John

2008-01-01

Objective Assess patient knowledge of and response to drug cost sharing. Study Setting Adult members of a large prepaid, integrated delivery system. Study Design/Data Collection Telephone interviews with 932 participants (72 percent response rate) who reported knowledge of the structures and amounts of their prescription drug cost sharing. Participants reported cost-related changes in their drug adherence, any financial burden, and other cost-coping behaviors. Actual cost sharing amounts came from administrative databases. Principal Findings Overall, 27 percent of patients knew all of their drug cost sharing structures and amounts. After adjustment for individual characteristics, additional patient cost sharing structures (tiers and caps), and higher copayment amounts were associated with reporting decreased adherence, financial burden, or other cost-coping behaviors. Conclusions Patient knowledge of their drug benefits is limited, especially for more complex cost sharing structures. Patients also report a range of responses to greater cost sharing, including decreasing adherence. PMID:18370979

Data sharing in the ag community - what are current challenges, benefits, and opportunities

USDA-ARS?s Scientific Manuscript database

The model for building agronomic science today and into the future to meet global food demands with limited resources will be through public-private data acquisition, sharing, and collaborative analysis. The public perspective focuses on preserving natural resources. The private perspective focuses ...

DISTRIBUTION AND CAUSES OF GLOBAL FOREST FRAGMENTATION

EPA Science Inventory

Because human land uses tend to expand over time, forests that share a high proportion of their borders with anthropogenic uses are at higher risk of further degradation than forests that share a high proportion of their borders with non-forest, natural land cover (e.g. wetland)....

Koinonia: The Requirements and Vision for an Unclassified Information-Sharing System

DTIC Science & Technology

2013-06-01

of an effort to share information with multinational partners in Multinational Planning Augmentation Team (MPAT) ( Tempest Express Fact Sheet 2011... Tempest fact sheet. Global Security.org. May 7, 2011. Accessed May 3, 2013. http://www.globalsecurity.org/military/ops/ tempest -express.htm U.S

Enabling innovative research by supporting the life cycle of high frequency streaming sensor data in the Global Lake Ecological Observatory Network (GLEON)

NASA Astrophysics Data System (ADS)

Gries, C.; Read, J. S.; Winslow, L. A.; Hanson, P. C.; Weathers, K. C.

2014-12-01

The Global Lake Ecological Observatory Network (GLEON) is an international community of scientists, educators and citizens with the mission to conduct innovative science by sharing and interpreting high-resolution sensor data to understand, predict and communicate the role and response of lakes in a changing global environment. During its almost ten years of existence and continual growth, GLEON has inspired innovative science, new modeling approaches, and accumulated extensive experience in the management of streaming, high resolution, and large volume data. However, a recent 'data task force' identified inhibiting data infrastructure issues, including providing access to data, discovering distributed data, and integrating data into useful data products for scientific research and management. Accordingly, in support of the complete data lifecycle, tools are being developed by the GLEON community and integrated with innovative technology from other groups to improve environmental observations data management in the broader community. Specifically we will discuss raw data handling with tools developed by the Consortium of Universities for the Advancement of Hydrologic Sciences (CUAHSI, Observation Data Model and DataLoader), quality control practices using a newly developed R package (sensorQC), data access with HydroDesktop, or webservices delivering WaterML, data analysis with the R package rLakeAnalyzer, and final storage of the quality controlled, harmonized and value added data product in a DataONE member node. Such data product is then discoverable, accessible for new analyses and citable in subsequent publications. Leveraging GLEON's organizational structure, community trust, extensive experience, and technological talent the goal is to develop a design and implementation plan for a data publishing and sharing system that will address not only GLEON's needs, but also those of other environmental research communities.

Stakeholders understanding of the concept of benefit sharing in health research in Kenya: a qualitative study.

PubMed

Lairumbi, Geoffrey M; Parker, Michael; Fitzpatrick, Raymond; Mike, English C

2011-10-03

The concept of benefit sharing to enhance the social value of global health research in resource poor settings is now a key strategy for addressing moral issues of relevance to individuals, communities and host countries in resource poor settings when they participate in international collaborative health research.The influence of benefit sharing framework on the conduct of collaborative health research is for instance evidenced by the number of publications and research ethics guidelines that require prior engagement between stakeholders to determine the social value of research to the host communities. While such efforts as the production of international guidance on how to promote the social value of research through such strategies as benefit sharing have been made, the extent to which these ideas and guidelines have been absorbed by those engaged in global health research especially in resource poor settings remains unclear. We examine this awareness among stakeholders involved in health related research in Kenya. We conducted in-depth interviews with key informants drawn from within the broader health research system in Kenya including researchers from the mainstream health research institutions, networks and universities, teaching hospitals, policy makers, institutional review boards, civil society organisations and community representative groups. Our study suggests that although people have a sense of justice and the moral aspects of research, this was not articulated in terms used in the literature and the guidelines on the ethics of global health research. This study demonstrates that while in theory several efforts can be made to address the moral issues of concern to research participants and their communities in resource poor settings, quick fixes such as benefit sharing are not going to be straightforward. We suggest a need to pay closer attention to the processes through which ethical principles are enacted in practice and distil lessons on how best to involve individuals and communities in promoting ethical conduct of global health research in resource poor settings.

Stakeholders understanding of the concept of benefit sharing in health research in Kenya: a qualitative study

PubMed Central

2011-01-01

Background The concept of benefit sharing to enhance the social value of global health research in resource poor settings is now a key strategy for addressing moral issues of relevance to individuals, communities and host countries in resource poor settings when they participate in international collaborative health research. The influence of benefit sharing framework on the conduct of collaborative health research is for instance evidenced by the number of publications and research ethics guidelines that require prior engagement between stakeholders to determine the social value of research to the host communities. While such efforts as the production of international guidance on how to promote the social value of research through such strategies as benefit sharing have been made, the extent to which these ideas and guidelines have been absorbed by those engaged in global health research especially in resource poor settings remains unclear. We examine this awareness among stakeholders involved in health related research in Kenya. Methods We conducted in-depth interviews with key informants drawn from within the broader health research system in Kenya including researchers from the mainstream health research institutions, networks and universities, teaching hospitals, policy makers, institutional review boards, civil society organisations and community representative groups. Results Our study suggests that although people have a sense of justice and the moral aspects of research, this was not articulated in terms used in the literature and the guidelines on the ethics of global health research. Conclusion This study demonstrates that while in theory several efforts can be made to address the moral issues of concern to research participants and their communities in resource poor settings, quick fixes such as benefit sharing are not going to be straightforward. We suggest a need to pay closer attention to the processes through which ethical principles are enacted in practice and distil lessons on how best to involve individuals and communities in promoting ethical conduct of global health research in resource poor settings. PMID:21961798

Future energy system challenges for Africa: Insights from Integrated Assessment Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lucas, Paul; Nielsen, Jens; Calvin, Katherine V.

Although Africa’s share in the global energy system is only small today, the ongoing population growth and economic development imply that this can change significantly. In this paper, we discuss long-term energy developments in Africa using the results of the LIMITS model inter-comparison study. The analysis focusses on the position of Africa in the wider global energy system and climate mitigation. The results show a considerable spread in model outcomes. Without specific climate policy, Africa’s share in global CO 2 emissions is projected to increase from around 1-4% today to 3-23% by 2100. In all models, emissions only start tomore » become really significant on a global scale after 2050. Furthermore, by 2030 still around 50% of total household energy use is supplied through traditional bio-energy, in contrast to existing ambitions from international organisations to provide access to modern energy for all. After 2050, the energy mix is projected to converge towards a global average energy mix with high shares of fossil fuels and electricity use. Finally, although the continent is now a large net exporter of oil and gas, towards 2050 it most likely needs most of its resources to meet its rapidly growing domestic demand. With respect to climate policy, the rapid expansion of the industrial and the power sector also create large mitigation potential and thereby the possibility to align the investment peak in the energy system with climate policy and potential revenues from international carbon trading.« less

77 FR 58412 - Meeting of the Global Justice Information Sharing Initiative Federal Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

... described at www.it.ojp.gov/global . DATES: The meeting will take place on Wednesday, October 24, 2012, from...: This is not a toll-free number]; Email: [email protected]gov . SUPPLEMENTARY INFORMATION: This...

78 FR 57178 - Meeting of the Global Justice Information Sharing Initiative Federal Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-17

... described at www.it.ojp.gov/global . DATES: The meeting will take place on Wednesday, October 30, 2013, from...) 616-0532 [note: this is not a toll-free number]; Email: [email protected]gov . SUPPLEMENTARY...

Global Data Spatially Interrelate System for Scientific Big Data Spatial-Seamless Sharing

NASA Astrophysics Data System (ADS)

Yu, J.; Wu, L.; Yang, Y.; Lei, X.; He, W.

2014-04-01

A good data sharing system with spatial-seamless services will prevent the scientists from tedious, boring, and time consuming work of spatial transformation, and hence encourage the usage of the scientific data, and increase the scientific innovation. Having been adopted as the framework of Earth datasets by Group on Earth Observation (GEO), Earth System Spatial Grid (ESSG) is potential to be the spatial reference of the Earth datasets. Based on the implementation of ESSG, SDOG-ESSG, a data sharing system named global data spatially interrelate system (GASE) was design to make the data sharing spatial-seamless. The architecture of GASE was introduced. The implementation of the two key components, V-Pools, and interrelating engine, and the prototype is presented. Any dataset is firstly resampled into SDOG-ESSG, and is divided into small blocks, and then are mapped into hierarchical system of the distributed file system in V-Pools, which together makes the data serving at a uniform spatial reference and at a high efficiency. Besides, the datasets from different data centres are interrelated by the interrelating engine at the uniform spatial reference of SDOGESSG, which enables the system to sharing the open datasets in the internet spatial-seamless.

CaLRS: A Critical-Aware Shared LLC Request Scheduling Algorithm on GPGPU

PubMed Central

Ma, Jianliang; Meng, Jinglei; Chen, Tianzhou; Wu, Minghui

2015-01-01

Ultra high thread-level parallelism in modern GPUs usually introduces numerous memory requests simultaneously. So there are always plenty of memory requests waiting at each bank of the shared LLC (L2 in this paper) and global memory. For global memory, various schedulers have already been developed to adjust the request sequence. But we find few work has ever focused on the service sequence on the shared LLC. We measured that a big number of GPU applications always queue at LLC bank for services, which provide opportunity to optimize the service order on LLC. Through adjusting the GPU memory request service order, we can improve the schedulability of SM. So we proposed a critical-aware shared LLC request scheduling algorithm (CaLRS) in this paper. The priority representative of memory request is critical for CaLRS. We use the number of memory requests that originate from the same warp but have not been serviced when they arrive at the shared LLC bank to represent the criticality of each warp. Experiments show that the proposed scheme can boost the SM schedulability effectively by promoting the scheduling priority of the memory requests with high criticality and improves the performance of GPU indirectly. PMID:25729772

The use of the Hurst exponent to investigate the global maximum of the Warsaw Stock Exchange WIG20 index

NASA Astrophysics Data System (ADS)

Domino, Krzysztof

2012-01-01

The WIG20 index-the index of the 20 biggest companies traded on the Warsaw Stock Exchange-reached the global maximum on 29th October 2007. I have used the local DFA (Detrended Functional Analysis) to obtain the Hurst exponent (diffusion exponent) and investigate the signature of anti-correlation of share price evolution around the maximum. The analysis was applied to the share price evolution for variable DFA parameters. For many values of parameters, the evidence of anti-correlation near the WIG20 maximum was pointed out.

The environmental impact of fertilizer embodied in a wheat-to-bread supply chain.

PubMed

Goucher, Liam; Bruce, Richard; Cameron, Duncan D; Lenny Koh, S C; Horton, Peter

2017-03-01

Food production and consumption cause approximately one-third of total greenhouse gas emissions 1-3 , and therefore delivering food security challenges not only the capacity of our agricultural system, but also its environmental sustainability 4-7 . Knowing where and at what level environmental impacts occur within particular food supply chains is necessary if farmers, agri-food industries and consumers are to share responsibility to mitigate these impacts 7,8 . Here we present an analysis of a complete supply chain for a staple of the global diet, a loaf of bread. We obtained primary data for all the processes involved in the farming, production and transport systems that lead to the manufacture of a particular brand of 800 g loaf. The data were analysed using an advanced life cycle assessment (LCA) tool 9 , yielding metrics of environmental impact, including greenhouse gas emissions. We show that more than half of the environmental impact of producing the loaf of bread arises directly from wheat cultivation, with the use of ammonium nitrate fertilizer alone accounting for around 40%. These findings reveal the dependency of bread production on the unsustainable use of fertilizer and illustrate the detail needed if the actors in the supply chain are to assume shared responsibility for achieving sustainable food production.

Values, trust and science - building trust in today's food system in an era of radical transparency.

PubMed

Arnot, Charlie; Vizzier-Thaxton, Yvonne; Scanes, Colin G

2016-07-21

Public concern exists globally about the food system and both the practices and the intensification of animal agriculture. Examples are presented of public opinion in North America, the European Union, and the People's Republic of China. Negative perceptions increase with distance from production agriculture. Even animal science faculty members do not uniformly support present production practices. Public trust in the food system is based on consumers' or public confidence (shared values based on corporate and institutional social responsibility or their fiduciary responsibility), competence of the people or groups providing the information and the influence of others (e.g., friends and family). Producer or company discussion of issues has focused on competency and "the science" when confidence is markedly more important to consumers and more effective. It is argued that the food system largely escapes regulation by federal and state governments by a social license based on public confidence. However, a tipping point(s) exists such that a crisis could greatly diminish public confidence and end the social license and bring with it increases in regulation. Advocacy for production agriculture (poultry and livestock) needs to incorporate recognition of the need to reaffirm the public's trust, assuring shared values together with an emphasis on good science. © 2016 Poultry Science Association Inc.

Modeling and assessing international climate financing

NASA Astrophysics Data System (ADS)

Wu, Jing; Tang, Lichun; Mohamed, Rayman; Zhu, Qianting; Wang, Zheng

2016-06-01

Climate financing is a key issue in current negotiations on climate protection. This study establishes a climate financing model based on a mechanism in which donor countries set up funds for climate financing and recipient countries use the funds exclusively for carbon emission reduction. The burden-sharing principles are based on GDP, historical emissions, and consumptionbased emissions. Using this model, we develop and analyze a series of scenario simulations, including a financing program negotiated at the Cancun Climate Change Conference (2010) and several subsequent programs. Results show that sustained climate financing can help to combat global climate change. However, the Cancun Agreements are projected to result in a reduction of only 0.01°C in global warming by 2100 compared to the scenario without climate financing. Longer-term climate financing programs should be established to achieve more significant benefits. Our model and simulations also show that climate financing has economic benefits for developing countries. Developed countries will suffer a slight GDP loss in the early stages of climate financing, but the longterm economic growth and the eventual benefits of climate mitigation will compensate for this slight loss. Different burden-sharing principles have very similar effects on global temperature change and economic growth of recipient countries, but they do result in differences in GDP changes for Japan and the FSU. The GDP-based principle results in a larger share of financial burden for Japan, while the historical emissions-based principle results in a larger share of financial burden for the FSU. A larger burden share leads to a greater GDP loss.

Graduating to Postdoc: Information-Sharing in Support of Organizational Structures and Needs

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Lucas, Paul J.; Compton, Michael M.; Stewart, Helen J.; Baya, Vinod; DelAlto, Martha

1999-01-01

The deployment of information-sharing systems in large organizations can significantly impact existing policies and procedures with regard to authority and control over information. Unless information-sharing systems explicitly support organizational structures and needs, these systems will be rejected summarily. The Postdoc system is a deployed Web-based information-sharing system created specifically to address organizational needs. Postdoc contains various organizational support features including a shared, globally navigable document space, as well as specialized access control, distributed administration, and mailing list features built around the key notion of hierarchical group structures. We review successes and difficulties in supporting organizational needs with Postdoc

Globalizing Lessons Learned from Regional-scale Observatories

NASA Astrophysics Data System (ADS)

Glenn, S. M.

2016-02-01

The Mid Atlantic Regional Association Coastal Ocean Observing System (MARACOOS) has accumulated a decade of experience designing, building and operating a Regional Coastal Ocean Observing System for the U.S. Integrated Ocean Observing System (IOOS). MARACOOS serves societal goals and supports scientific discovery at the scale of a Large Marine Ecosystem (LME). Societal themes include maritime safety, ecosystem decision support, coastal inundation, water quality and offshore energy. Scientific results that feed back on societal goals with better products include improved understanding of seasonal transport pathways and their impact on phytoplankton blooms and hypoxia, seasonal evolution of the subsurface Mid Atlantic Cold Pool and its impact on fisheries, biogeochemical transformations in coastal plumes, coastal ocean evolution and impact on hurricane intensities, and storm sediment transport pathways. As the global ocean observing requirements grow to support additional societal needs for information on fisheries and aquaculture, ocean acidification and deoxygenation, water quality and offshore development, global observing will necessarily evolve to include more coastal observations and forecast models at the scale of the world's many LMEs. Here we describe our efforts to share lessons learned between the observatory operators at the regional-scale of the LMEs. Current collaborators are spread across Europe, and also include Korea, Indonesia, Australia, Brazil and South Africa. Specific examples include the development of a world standard QA/QC approach for HF Radar data that will foster the sharing of data between countries, basin-scale underwater glider missions between internationally-distributed glider ports to developed a shared understanding of operations and an ongoing evaluation of the global ocean models in which the regional models for the LME will be nested, and joint training programs to develop the distributed teams of scientists and technicians required to support the global network. Globalization includes the development of international networks to coordinate activities, such as the Global HF Radar network supported by GEO, the global Everyone's Glider Organization supported by WMO and IOC, and the need for professional training supported by MTS.

Telling War Stories: The Things They Carry

ERIC Educational Resources Information Center

Paquette, Paige; Warren, Mike

2010-01-01

This webtext reveals two modern-day methods for soldiers to share their war stories: 1) soldiers sharing their stories with cadets from West Point through a project linking veterans from the Global War on Terror with composition students; and 2) soldiers learning in online composition classrooms designed specifically for them.

Quantifying Biodiversity Losses Due to Human Consumption: A Global-Scale Footprint Analysis.

PubMed

Wilting, Harry C; Schipper, Aafke M; Bakkenes, Michel; Meijer, Johan R; Huijbregts, Mark A J

2017-03-21

It is increasingly recognized that human consumption leads to considerable losses of biodiversity. This study is the first to systematically quantify these losses in relation to land use and greenhouse gas (GHG) emissions associated with the production and consumption of (inter)nationally traded goods and services by presenting consumption-based biodiversity losses, in short biodiversity footprint, for 45 countries and world regions globally. Our results showed that (i) the biodiversity loss per citizen shows large variations among countries, with higher values when per-capita income increases; (ii) the share of biodiversity losses due to GHG emissions in the biodiversity footprint increases with income; (iii) food consumption is the most important driver of biodiversity loss in most of the countries and regions, with a global average of 40%; (iv) more than 50% of the biodiversity loss associated with consumption in developed economies occurs outside their territorial boundaries; and (v) the biodiversity footprint per dollar consumed is lower for wealthier countries. The insights provided by our analysis might support policymakers in developing adequate responses to avert further losses of biodiversity when population and incomes increase. Both the mitigation of GHG emissions and land use related reduction options in production and consumption should be considered in strategies to protect global biodiversity.

How are streamflow responses to the El Nino Southern Oscillation affected by watershed characteristics?

NASA Astrophysics Data System (ADS)

Rice, Joshua S.; Emanuel, Ryan E.

2017-05-01

Understanding the factors that influence how global climate phenomena, such as the El-Nino Southern Oscillation (ENSO), affect streamflow behavior is an important area of research in the hydrologic sciences. While large-scale patterns in ENSO-streamflow relationships have been thoroughly studied, and are relatively well-understood, information is scarce concerning factors that affect variation in ENSO responses from one watershed to another. To this end, we examined relationships between variability in ENSO activity and streamflow for 2731 watersheds across the conterminous U.S. from 1970 to 2014 using a novel approach to account for the intermediary role of precipitation. We applied an ensemble of regression techniques to describe relationships between variability in ENSO activity and streamflow as a function of watershed characteristics including: hydroclimate, topography, geomorphology, geographic location, land cover, soil characteristics, bedrock geology, and anthropogenic influences. We found that variability in watershed scale ENSO-streamflow relationships was strongly related to factors including: precipitation timing and phase, forest cover, and interactions between watershed topography and geomorphology. These, and other influential factors, share in common the ability to affect the partitioning and movement of water within watersheds. Our results demonstrate that the conceptualization of watersheds as signal filters for hydroclimate inputs, commonly applied to short-term rainfall-runoff responses, also applies to long-term hydrologic responses to sources of recurrent climate variability. These results also show that watershed processes, which are typically studied at relatively fine spatial scales, are also critical for understanding continental scale hydrologic responses to global climate.

Sustaining the Civil Reserve Air Fleet (CRAF) Program

DTIC Science & Technology

2003-05-01

means to build international networks and global marketing alliances. These arrangements have permitted alliances to exploit the regional competitive...next major phase occurred in the 1990s—the linking of networks in different countries through code sharing alliances and global marketing alliances

Tuition Fees and Student Financial Assistance: 2010 Global Year

ERIC Educational Resources Information Center

Marcucci, Pamela; Usher, Alex

2011-01-01

Since the start of the global financial crisis a little over two years ago, many concerns have been raised on how it might affect funding to higher education and whether or not it might hasten moves toward greater cost sharing. While, globally, some steps have been taken in this direction, in most countries, hard decisions have yet to be taken on…

The Determination of Children's Knowledge of Global Lunar Patterns from Online Essays Using Text Mining Analysis

ERIC Educational Resources Information Center

Cheon, Jongpil; Lee, Sangno; Smith, Walter; Song, Jaeki; Kim, Yongjin

2013-01-01

The purpose of this study was to use text mining analysis of early adolescents' online essays to determine their knowledge of global lunar patterns. Australian and American students in grades five to seven wrote about global lunar patterns they had discovered by sharing observations with each other via the Internet. These essays were analyzed for…

Linking global scenarios to national assessments: Experiences from the Resources Planning Act (RPA) Assessment

Treesearch

Linda L. Langner; Peter J. Ince

2012-01-01

The Resources Planning Act (RPA) Assessment provides a nationally consistent analysis of the status and trends of the Nation's renewable forest resources. A global scenario approach was taken for the 2010 RPA Assessment to provide a shared world view of potential futures. The RPA Assessment scenarios were linked to the global scenarios and climate projections used...

Globalization in the One World: Impacts on Education in Different Nations

ERIC Educational Resources Information Center

Pang, Nicholas Sun-keung

2013-01-01

There is only one world, but it is widely divided. All nations share a common interest in the investment and development of education in their own contexts. The one world has been undergoing tremendous, turbulent changes, due to the recent quick movement in globalization. This paper aims to explore what is meant by globalization, how it has…

Global-local processing relates to spatial and verbal processing: implications for sex differences in cognition.

PubMed

Pletzer, Belinda; Scheuringer, Andrea; Scherndl, Thomas

2017-09-05

Sex differences have been reported for a variety of cognitive tasks and related to the use of different cognitive processing styles in men and women. It was recently argued that these processing styles share some characteristics across tasks, i.e. male approaches are oriented towards holistic stimulus aspects and female approaches are oriented towards stimulus details. In that respect, sex-dependent cognitive processing styles share similarities with attentional global-local processing. A direct relationship between cognitive processing and global-local processing has however not been previously established. In the present study, 49 men and 44 women completed a Navon paradigm and a Kimchi Palmer task as well as a navigation task and a verbal fluency task with the goal to relate the global advantage (GA) effect as a measure of global processing to holistic processing styles in both tasks. Indeed participants with larger GA effects displayed more holistic processing during spatial navigation and phonemic fluency. However, the relationship to cognitive processing styles was modulated by the specific condition of the Navon paradigm, as well as the sex of participants. Thus, different types of global-local processing play different roles for cognitive processing in men and women.

Estimating source-attributable health impacts of ambient fine particulate matter exposure: global premature mortality from surface transportation emissions in 2005

NASA Astrophysics Data System (ADS)

Chambliss, S. E.; Silva, R.; West, J. J.; Zeinali, M.; Minjares, R.

2014-10-01

Exposure to ambient fine particular matter (PM2.5) was responsible for 3.2 million premature deaths in 2010 and is among the top ten leading risk factors for early death. Surface transportation is a significant global source of PM2.5 emissions and a target for new actions. The objective of this study is to estimate the global and national health burden of ambient PM2.5 exposure attributable to surface transportation emissions. This share of health burden is called the transportation attributable fraction (TAF), and is assumed equal to the proportional decrease in modeled ambient particulate matter concentrations when surface transportation emissions are removed. National population-weighted TAFs for 190 countries are modeled for 2005 using the MOZART-4 global chemical transport model. Changes in annual average concentration of PM2.5 at 0.5 × 0.67 degree horizontal resolution are based on a global emissions inventory and removal of all surface transportation emissions. Global population-weighted average TAF was 8.5 percent or 1.75 μg m-3 in 2005. Approximately 242 000 annual premature deaths were attributable to surface transportation emissions, dominated by China, the United States, the European Union and India. This application of TAF allows future Global Burden of Disease studies to estimate the sector-specific burden of ambient PM2.5 exposure. Additional research is needed to capture intraurban variations in emissions and exposure, and to broaden the range of health effects considered, including the effects of other pollutants.

What perceptions do patients have of decision making (DM)? Toward an integrative patient-centered care model. A qualitative study using focus-group interviews.

PubMed

Moreau, Alain; Carol, Laurent; Dedianne, Marie Cécile; Dupraz, Christian; Perdrix, Corinne; Lainé, Xavier; Souweine, Gilbert

2012-05-01

To understand patients' perceptions of decision making and identify relationships among decision-making models. This qualitative study was made up of four focus group interviews (elderly persons, users of health support groups, students, and rural inhabitants). Participants were asked to report their perceptions of decision making in three written clinical scenarios (hypertension, breast cancer, prostate cancer). The analysis was based on the principles of grounded theory. Most patients perceived decision making as shared decision making, a deliberative question-response interaction with the physician that allowed patients to be experts in obtaining clearer information, participating in the care process, and negotiating compromises with physician preferences. Requesting second opinions allowed patients to maintain control, even within the paternalistic model preferred by elderly persons. Facilitating factors (trust, qualitative non-verbal communication, time to think) and obstacles (serious/emergency situations, perceived inadequate scientific competence, problems making requests, fear of knowing) were also part of shared decision making. In the global concept of patient-centered care, shared decision making can be flexible and can integrate paternalistic and informative models. Physicians' expertise should be associated with biomedical and relational skills through listening to, informing, and advising patients, and by supporting patients' choices. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Sharing Earth Observation Data When Health Management

NASA Astrophysics Data System (ADS)

Cox, E. L., Jr.

2015-12-01

While the global community is struck by pandemics and epidemics from time to time the ability to fully utilize earth observations and integrate environmental information has been limited - until recently. Mature science understanding is allowing new levels of situational awareness be possible when and if the relevant data is available and shared in a timely and useable manner. Satellite and other remote sensing tools have been used to observe, monitor, assess and predict weather and water impacts for decades. In the last few years much of this has included a focus on the ability to monitor changes on climate scales that suggest changes in quantity and quality of ecosystem resources or the "one-health" approach where trans-disciplinary links between environment, animal and vegetative health may provide indications of best ways to manage susceptibility to infectious disease or outbreaks. But the scale of impacts and availability of information from earth observing satellites, airborne platforms, health tracking systems and surveillance networks offer new integrated tools. This presentation will describe several recent events, such as Superstorm Sandy in the United States and the Ebola outbreak in Africa, where public health and health infrastructure have been exposed to environmental hazards and lessons learned from disaster response in the ability to share data have been effective in risk reduction.

Juno Mission Simulation

NASA Technical Reports Server (NTRS)

Lee, Meemong; Weidner, Richard J.

2008-01-01

The Juno spacecraft is planned to launch in August of 2012 and would arrive at Jupiter four years later. The spacecraft would spend more than one year orbiting the planet and investigating the existence of an ice-rock core; determining the amount of global water and ammonia present in the atmosphere, studying convection and deep- wind profiles in the atmosphere; investigating the origin of the Jovian magnetic field, and exploring the polar magnetosphere. Juno mission management is responsible for mission and navigation design, mission operation planning, and ground-data-system development. In order to ensure successful mission management from initial checkout to final de-orbit, it is critical to share a common vision of the entire mission operation phases with the rest of the project teams. Two major challenges are 1) how to develop a shared vision that can be appreciated by all of the project teams of diverse disciplines and expertise, and 2) how to continuously evolve a shared vision as the project lifecycle progresses from formulation phase to operation phase. The Juno mission simulation team addresses these challenges by developing agile and progressive mission models, operation simulations, and real-time visualization products. This paper presents mission simulation visualization network (MSVN) technology that has enabled a comprehensive mission simulation suite (MSVN-Juno) for the Juno project.

Assessing uncertainties in global cropland futures using a conditional probabilistic modelling framework

NASA Astrophysics Data System (ADS)

Engström, Kerstin; Olin, Stefan; Rounsevell, Mark D. A.; Brogaard, Sara; van Vuuren, Detlef P.; Alexander, Peter; Murray-Rust, Dave; Arneth, Almut

2016-11-01

We present a modelling framework to simulate probabilistic futures of global cropland areas that are conditional on the SSP (shared socio-economic pathway) scenarios. Simulations are based on the Parsimonious Land Use Model (PLUM) linked with the global dynamic vegetation model LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator) using socio-economic data from the SSPs and climate data from the RCPs (representative concentration pathways). The simulated range of global cropland is 893-2380 Mha in 2100 (± 1 standard deviation), with the main uncertainties arising from differences in the socio-economic conditions prescribed by the SSP scenarios and the assumptions that underpin the translation of qualitative SSP storylines into quantitative model input parameters. Uncertainties in the assumptions for population growth, technological change and cropland degradation were found to be the most important for global cropland, while uncertainty in food consumption had less influence on the results. The uncertainties arising from climate variability and the differences between climate change scenarios do not strongly affect the range of global cropland futures. Some overlap occurred across all of the conditional probabilistic futures, except for those based on SSP3. We conclude that completely different socio-economic and climate change futures, although sharing low to medium population development, can result in very similar cropland areas on the aggregated global scale.

Ultra-Porous Nanoparticle Networks: A Biomimetic Coating Morphology for Enhanced Cellular Response and Infiltration

PubMed Central

Nasiri, Noushin; Ceramidas, Anthony; Mukherjee, Shayanti; Panneerselvan, Anitha; Nisbet, David R.; Tricoli, Antonio

2016-01-01

Orthopedic treatments are amongst the most common cause of surgery and are responsible for a large share of global healthcare expenditures. Engineering materials that can hasten bone integration will improve the quality of life of millions of patients per year and reduce associated medical costs. Here, we present a novel hierarchical biomimetic coating that mimics the inorganic constituent of mammalian bones with the aim of improving osseointegration of metallic implants. We exploit the thermally-driven self-organization of metastable core-shell nanoparticles during their aerosol self-assembly to rapidly fabricate robust, ultra-porous nanoparticle networks (UNN) of crystalline hydroxyapatite (HAp). Comparative analysis of the response of osteoblast cells to the ultra-porous nanostructured HAp surfaces and to the spin coated HAp surfaces revealed superior osseointegrative properties of the UNN coatings with significant cell and filopodia infiltration. This flexible synthesis approach for the engineering of UNN HAp coatings on titanium implants provides a platform technology to study the bone-implant interface for improved osseointegration and osteoconduction. PMID:27076035

Promoting research integrity in the geosciences

NASA Astrophysics Data System (ADS)

Mayer, Tony

2015-04-01

Conducting research in a responsible manner in compliance with codes of research integrity is essential. The geosciences, as with all other areas of research endeavour, has its fair share of misconduct cases and causes celebres. As research becomes more global, more collaborative and more cross-disciplinary, the need for all concerned to work to the same high standards becomes imperative. Modern technology makes it far easier to 'cut and paste', to use Photoshop to manipulate imagery to falsify results at the same time as making research easier and more meaningful. So we need to promote the highest standards of research integrity and the responsible conduct of research. While ultimately, responsibility for misconduct rests with the individual, institutions and the academic research system have to take steps to alleviate the pressure on researchers and promote good practice through training programmes and mentoring. The role of the World Conferences on Research Integrity in promoting the importance of research integrity and statements about good practice will be presented and the need for training and mentoring programmes will be discussed

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

PubMed

Keenan, Alexandra B; Jenkins, Sherry L; Jagodnik, Kathleen M; Koplev, Simon; He, Edward; Torre, Denis; Wang, Zichen; Dohlman, Anders B; Silverstein, Moshe C; Lachmann, Alexander; Kuleshov, Maxim V; Ma'ayan, Avi; Stathias, Vasileios; Terryn, Raymond; Cooper, Daniel; Forlin, Michele; Koleti, Amar; Vidovic, Dusica; Chung, Caty; Schürer, Stephan C; Vasiliauskas, Jouzas; Pilarczyk, Marcin; Shamsaei, Behrouz; Fazel, Mehdi; Ren, Yan; Niu, Wen; Clark, Nicholas A; White, Shana; Mahi, Naim; Zhang, Lixia; Kouril, Michal; Reichard, John F; Sivaganesan, Siva; Medvedovic, Mario; Meller, Jaroslaw; Koch, Rick J; Birtwistle, Marc R; Iyengar, Ravi; Sobie, Eric A; Azeloglu, Evren U; Kaye, Julia; Osterloh, Jeannette; Haston, Kelly; Kalra, Jaslin; Finkbiener, Steve; Li, Jonathan; Milani, Pamela; Adam, Miriam; Escalante-Chong, Renan; Sachs, Karen; Lenail, Alex; Ramamoorthy, Divya; Fraenkel, Ernest; Daigle, Gavin; Hussain, Uzma; Coye, Alyssa; Rothstein, Jeffrey; Sareen, Dhruv; Ornelas, Loren; Banuelos, Maria; Mandefro, Berhan; Ho, Ritchie; Svendsen, Clive N; Lim, Ryan G; Stocksdale, Jennifer; Casale, Malcolm S; Thompson, Terri G; Wu, Jie; Thompson, Leslie M; Dardov, Victoria; Venkatraman, Vidya; Matlock, Andrea; Van Eyk, Jennifer E; Jaffe, Jacob D; Papanastasiou, Malvina; Subramanian, Aravind; Golub, Todd R; Erickson, Sean D; Fallahi-Sichani, Mohammad; Hafner, Marc; Gray, Nathanael S; Lin, Jia-Ren; Mills, Caitlin E; Muhlich, Jeremy L; Niepel, Mario; Shamu, Caroline E; Williams, Elizabeth H; Wrobel, David; Sorger, Peter K; Heiser, Laura M; Gray, Joe W; Korkola, James E; Mills, Gordon B; LaBarge, Mark; Feiler, Heidi S; Dane, Mark A; Bucher, Elmar; Nederlof, Michel; Sudar, Damir; Gross, Sean; Kilburn, David F; Smith, Rebecca; Devlin, Kaylyn; Margolis, Ron; Derr, Leslie; Lee, Albert; Pillai, Ajay

2018-01-24

The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program that catalogs how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by LINCS include experimental and computational methods, visualization tools, molecular and imaging data, and signatures. By assembling an integrated picture of the range of responses of human cells exposed to many perturbations, the LINCS program aims to better understand human disease and to advance the development of new therapies. Perturbations under study include drugs, genetic perturbations, tissue micro-environments, antibodies, and disease-causing mutations. Responses to perturbations are measured by transcript profiling, mass spectrometry, cell imaging, and biochemical methods, among other assays. The LINCS program focuses on cellular physiology shared among tissues and cell types relevant to an array of diseases, including cancer, heart disease, and neurodegenerative disorders. This Perspective describes LINCS technologies, datasets, tools, and approaches to data accessibility and reusability. Copyright © 2017 Elsevier Inc. All rights reserved.

How Jordan and Saudi Arabia are avoiding a tragedy of the commons over shared groundwater

NASA Astrophysics Data System (ADS)

Müller, Marc F.; Müller-Itten, Michèle C.; Gorelick, Steven M.

2017-07-01

Transboundary aquifers are ubiquitous and strategically important to global food and water security. Yet these shared resources are being depleted at an alarming rate. Focusing on the Disi aquifer, a key nonrenewable source of groundwater shared by Jordan and Saudi Arabia, this study develops a two-stage game that evaluates optimal transboundary strategies of common-pool resource exploitation under various assumptions. The analysis relies on estimates of agricultural water use from satellite imagery, which were obtained using three independent remote sensing approaches. Drawdown response to pumping is simulated using a 2-D regional aquifer model. Jordan and Saudi Arabia developed a buffer-zone strategy with a prescribed minimum distance between each country's pumping centers. We show that by limiting the marginal impact of pumping decisions on the other country's pumping costs, this strategy will likely avoid an impeding tragedy of the commons for at least 60 years. Our analysis underscores the role played by distance between wells and disparities in groundwater exploitation costs on common-pool overdraft. In effect, if pumping centers are distant enough, a shared aquifer no longer behaves as a common-pool resource and a tragedy of the commons can be avoided. The 2015 Disi aquifer pumping agreement between Jordan and Saudi Arabia, which in practice relies on a joint technical commission to enforce exclusion zones, is the first agreement of this type between sovereign countries and has a promising potential to avoid conflicts or resolve potential transboundary groundwater disputes over comparable aquifer systems elsewhere.

The United States President's Emergency Plan for AIDS Relief: a story of partnerships and smart investments to turn the tide of the global AIDS pandemic.

PubMed

Goosby, Eric; Dybul, Mark; Fauci, Anthony S; Fauci, Anthony A; Fu, Joe; Walsh, Thomas; Needle, Richard; Bouey, Paul

2012-08-15

The United States President's Emergency Plan for AIDS Relief (PEPFAR) has played a key leadership role in the global response to the HIV/AIDS pandemic. PEPFAR was inspired by the principles of the historic Monterrey Consensus (United Nations. Monterrey Consensus on Financing for Development, Monterrey, Mexico, March 18-22, 2002. New York: United Nations; 2002. Available at: http://www.un.org/esa/ffd/monterrey/MonterreyConsensus.pdf. Accessed April 21, 2012), which changed the underlying conceptual framework for international development, and therefore global health--a shift from paternalism to partnership that begins with country ownership and requires good governance, a results-based approach, and engagement of all sectors of society. PEPFAR began with a focus on the growing emergency of the HIV/AIDS pandemic by rapidly expanding HIV services, building clinical capacity, implementing strategic information systems, and building a coalition of partners to lead the response. Within the first years of implementation, there was a shift to sustainability, including the advent of Partnership Frameworks. The PEPFAR reauthorization in 2008 codified into law, the evolution in policies and programs for the next phase of implementation. In 2011 alone, PEPFAR supported nearly 4 million people on treatment, supported programs that provided more than 1.5 million HIV-positive pregnant women with antiretroviral drugs to prevent HIV transmission to their children, and supported HIV testing for more than 40 million people. This article provides an overview of how smart investments and partnerships across sectors and US agencies have helped achieve unprecedented results in increasing HIV/AIDS services and engaging partner countries and organizations in sharing the responsibility for an AIDS-free generation.

Global Transcriptional Analysis Reveals the Complex Relationship between Tea Quality, Leaf Senescence and the Responses to Cold-Drought Combined Stress in Camellia sinensis

PubMed Central

Zheng, Chao; Wang, Yu; Ding, Zhaotang; Zhao, Lei

2016-01-01

In field conditions, especially in arid and semi-arid areas, tea plants are often simultaneously exposed to various abiotic stresses such as cold and drought, which have profound effects on leaf senescence process and tea quality. However, most studies of gene expression in stress responses focus on a single inciting agent, and the confounding effect of multiple stresses on crop quality and leaf senescence remain unearthed. Here, global transcriptome profiles of tea leaves under separately cold and drought stress were compared with their combination using RNA-Seq technology. This revealed that tea plants shared a large overlap in unigenes displayed “similar” (26%) expression pattern and avoid antagonistic responses (lowest level of “prioritized” mode: 0%) to exhibit very congruent responses to co-occurring cold and drought stress; 31.5% differential expressed genes and 38% of the transcriptome changes in response to combined stresses were unpredictable from cold or drought single-case studies. We also identified 319 candidate genes for enhancing plant resistance to combined stress. We then investigated the combined effect of cold and drought on tea quality and leaf senescence. Our results showed that drought-induced leaf senescence were severely delayed by (i) modulation of a number of senescence-associated genes and cold responsive genes, (ii) enhancement of antioxidant capacity, (iii) attenuation of lipid degradation, (iv) maintenance of cell wall and photosynthetic system, (v) alteration of senescence-induced sugar effect/sensitivity, as well as (vi) regulation of secondary metabolism pathways that significantly influence the quality of tea during combined stress. Therefore, care should be taken when utilizing a set of stresses to try and maximize leaf longevity and tea quality. PMID:28018394

The expression of Longus type 4 pilus of enterotoxigenic Escherichia coli is regulated by LngR and LngS and by H-NS, CpxR and CRP global regulators.

PubMed

De la Cruz, Miguel A; Ruiz-Tagle, Alejandro; Ares, Miguel A; Pacheco, Sabino; Yáñez, Jorge A; Cedillo, Lilia; Torres, Javier; Girón, Jorge A

2017-05-01

Enterotoxigenic Escherichia coli produces a long type 4 pilus called Longus. The regulatory elements and the environmental signals controlling the expression of Longus-encoding genes are unknown. We identified two genes lngR and lngS in the Longus operon, whose predicted products share homology with transcriptional regulators. Isogenic lngR and lngS mutants were considerably affected in transcription of lngA pilin gene. The expression of lngA, lngR and lngS genes was optimally expressed at 37°C at pH 7.5. The presence of glucose and sodium chloride had a positive effect on Longus expression. The presence of divalent ions, particularly calcium, appears to be an important stimulus for Longus production. In addition, we studied H-NS, CpxR and CRP global regulators, on Longus expression. The response regulator CpxR appears to function as a positive regulator of lng genes as the cpxR mutant showed reduced levels of lngRSA expression. In contrast, H-NS and CRP function as negative regulators since expression of lngA was up-regulated in isogenic hns and crp mutants. H-NS and CRP were required for salt- and glucose-mediated regulation of Longus. Our data suggest the existence of a complex regulatory network controlling Longus expression, involving both local and global regulators in response to different environmental signals. © 2016 Society for Applied Microbiology and John Wiley & Sons Ltd.

Running a network on a shoestring: the Global Invasive Species Information Network

USGS Publications Warehouse

Jarnevich, Catherine S.; Simpson, Annie; Graham, James J; Newman, Gregory J.; Bargeron, Chuck T.

2015-01-01

The Global Invasive Species Information Network (GISIN) was conceptualized in 2004 to aggregate and disseminate invasive species data in a standardized way. A decade later the GISIN community has implemented a data portal and three of six GISIN data aggregation models in the GISIN data exchange Protocol, including invasive species status information, resource URLs, and occurrence data. The portal is based on a protocol developed by representatives from 15 countries and 27 organizations of the global invasive species information management community. The GISIN has 19 data providers sharing 34,343 species status records, 1,693,073 occurrences, and 15,601 resource URLs. While the GISIN's goal is to be global, much of its data and funding are provided by the United States. Several initiatives use the GISIN as their information backbone, such as the Great Lakes Early Detection Network (GLEDN) and the North American Invasive Species Network (NAISN). Here we share several success stories and organizational challenges that remain.

The Currency of Consciousness: Neurology, Specialization, and the Global Practices of Medicine.

PubMed

Casper, Stephen T

2016-01-01

This article explores the formation of a global community of neurologists between 1918 and 1970. Relying chiefly upon documents located in Anglo-American archives, its argument follows a narrative from money to memory, and posits that this global community of neurologists formed not out of a shared science and medicine of the nervous system, but out of shared dispositions in tastes, values, and culture. The localism and heterogeneity of the science and medicine of the nervous system was in fact so pronounced that neurologists - especially when they worked as "global citizens" - were forced to focus upon their superficial commonalities rather than examine local distinctions. This avoidance of a direct effort to define the content of neurology - or at least to confront their differences - exercised a peculiar influence on the specialty. Neurologists and their "official memory" became negotiated, and even imagined constructs. Consequently, these diverse cultures were ultimately subordinated to dominant economic interests.

Mapping of Indian neuroscience research: a scientometric analysis of research output during 1999-2008.

PubMed

Bala, Adarsh; Gupta, B M

2010-01-01

This study analyses the research output in India in neurosciences during the period 1999-2008 and the analyses included research growth, rank, global publications' share, citation impact, share of international collaborative papers and major collaborative partner countries and patterns of research communication in most productive journals. It also analyses the characteristics of most productive institutions, authors and high-cited papers. The publication output and impact of India is also compared with China, Brazil and South Korea. Scopus Citation database was used for retrieving the publications' output of India and other countries in neurosciences during 1999-2008. India's global publications' share in neurosciences during the study period was 0.99% (with 4503 papers) and it ranked 21 st among the top 26 countries in neurosciences. The average annual publication growth rate was 11.37%, shared 17.34% of international collaborative papers and the average citation per paper was 4.21. India was far behind China, Brazil and South Korea in terms of publication output, citation quality and share of international collaborative papers in neurosciences. India is far behind in terms of publication output, citation quality and share of international collaborative papers in neurosciences when compared to other countries with an emerging economy. There is an urgent need to substantially increase the research activities in the field of neurosciences in India.

Network Computing Infrastructure to Share Tools and Data in Global Nuclear Energy Partnership

NASA Astrophysics Data System (ADS)

Kim, Guehee; Suzuki, Yoshio; Teshima, Naoya

CCSE/JAEA (Center for Computational Science and e-Systems/Japan Atomic Energy Agency) integrated a prototype system of a network computing infrastructure for sharing tools and data to support the U.S. and Japan collaboration in GNEP (Global Nuclear Energy Partnership). We focused on three technical issues to apply our information process infrastructure, which are accessibility, security, and usability. In designing the prototype system, we integrated and improved both network and Web technologies. For the accessibility issue, we adopted SSL-VPN (Security Socket Layer-Virtual Private Network) technology for the access beyond firewalls. For the security issue, we developed an authentication gateway based on the PKI (Public Key Infrastructure) authentication mechanism to strengthen the security. Also, we set fine access control policy to shared tools and data and used shared key based encryption method to protect tools and data against leakage to third parties. For the usability issue, we chose Web browsers as user interface and developed Web application to provide functions to support sharing tools and data. By using WebDAV (Web-based Distributed Authoring and Versioning) function, users can manipulate shared tools and data through the Windows-like folder environment. We implemented the prototype system in Grid infrastructure for atomic energy research: AEGIS (Atomic Energy Grid Infrastructure) developed by CCSE/JAEA. The prototype system was applied for the trial use in the first period of GNEP.

Civility on Community College Campuses: A Shared Responsibility

ERIC Educational Resources Information Center

Popovics, Alexander J.

2014-01-01

Means to foster civility and respect on community college campuses are presented. Faculty views are shared in relationship to maintaining appropriate behaviors on campuses. Shared responsibility, early intervention and clearly stated campus-wide policies are among suggested strategies for creating and maintaining a respectful environment.

Confucius Institutes: Distributed Leadership and Knowledge Sharing in a Worldwide Network

ERIC Educational Resources Information Center

Li, Hsi Chang; Mirmirani, Sam; Ilacqua, Joseph A.

2009-01-01

Purpose: The purpose of this paper is to focus on Confucius Institutes and assess the applicability of theories of leadership and knowledge sharing to multinational organizations and worldwide networks. Growth of multinational trade and decrease in international tension have facilitated the globalization of both profit-seeking and non-profit…

78 FR 11909 - Emerging Global Advisors, LLC, et al.; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-20

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30382; 812-14117] Emerging... Investment Company Act of 1940 (``Act'') for an exemption from sections 2(a)(32), 5(a)(1), 22(d) and 22(e) of... management investment companies to issue shares (``Shares'') redeemable in large aggregations only...

Begin with the Children

ERIC Educational Resources Information Center

Yarfoh, Charles H.

2011-01-01

Francis W. Parker School invited Charles H. Yarfoh, the founder of its sister school, to Chicago to share his vision and what it has meant to the students of his school, Tuskegee International, to be part of the global connection between the two schools. In a speech he delivered to the faculty, staff, and students, Yarfoh shares what education…

GLobal Integrated Design Environment (GLIDE): A Concurrent Engineering Application

NASA Technical Reports Server (NTRS)

McGuire, Melissa L.; Kunkel, Matthew R.; Smith, David A.

2010-01-01

The GLobal Integrated Design Environment (GLIDE) is a client-server software application purpose-built to mitigate issues associated with real time data sharing in concurrent engineering environments and to facilitate discipline-to-discipline interaction between multiple engineers and researchers. GLIDE is implemented in multiple programming languages utilizing standardized web protocols to enable secure parameter data sharing between engineers and researchers across the Internet in closed and/or widely distributed working environments. A well defined, HyperText Transfer Protocol (HTTP) based Application Programming Interface (API) to the GLIDE client/server environment enables users to interact with GLIDE, and each other, within common and familiar tools. One such common tool, Microsoft Excel (Microsoft Corporation), paired with its add-in API for GLIDE, is discussed in this paper. The top-level examples given demonstrate how this interface improves the efficiency of the design process of a concurrent engineering study while reducing potential errors associated with manually sharing information between study participants.

Extended Producer Responsibility and Product Stewardship for Tobacco Product Waste

PubMed Central

Curtis, Clifton; Collins, Susan; Cunningham, Shea; Stigler, Paula; Novotny, Thomas E

2015-01-01

This paper reviews several environmental principles, including Extended Producer Responsibility (EPR), Product Stewardship (PS), the Polluter Pays Principle (PPP), and the Precautionary Principle, as they may apply to tobacco product waste (TPW). The review addresses specific criteria that apply in deciding whether a particular toxic product should adhere to these principles; presents three case studies of similar approaches to other toxic and/or environmentally harmful products; and describes 10 possible interventions or policy actions that may help prevent, reduce, and mitigate the effects of TPW. EPR promotes total lifecycle environmental improvements, placing economic, physical, and informational responsibilities onto the tobacco industry, while PS complements EPR, but with responsibility shared by all parties involved in the tobacco product lifecycle. Both principles focus on toxic source reduction, post-consumer take-back, and final disposal of consumer products. These principles when applied to TPW have the potential to substantially decrease the environmental and public health harms of cigarette butts and other TPW throughout the world. TPW is the most commonly littered item picked up during environmental, urban, and coastal cleanups globally. PMID:26457262

On the different “worlds” of intra-organizational knowledge management: Understanding idiosyncratic variation in MNC cross-site knowledge-sharing practices

PubMed Central

Kasper, Helmut; Lehrer, Mark; Mühlbacher, Jürgen; Müller, Barbara

2013-01-01

This qualitative field study investigated cross-site knowledge sharing in a small sample of multinational corporations in three different MNC business contexts (global, multidomestic, transnational). The results disclose heterogeneous “worlds” of MNC knowledge sharing, ultimately raising the question as to whether the whole concept of MNC knowledge sharing covers a sufficiently unitary phenomenon to be meaningful. We derive a non-exhaustive typology of MNC knowledge-sharing practices: self-organizing knowledge sharing, technocratic knowledge sharing, and best practice knowledge sharing. Despite its limitations, this typology helps to elucidate a number of issues, including the latent conflict between two disparate theories of MNC knowledge sharing, namely “sender–receiver” and “social learning” theories (Noorderhaven & Harzing, 2009). More generally, we develop the term “knowledge contextualization” to highlight the way that firm-specific organizational features pre-define which knowledge is considered to be of special relevance for intra-organizational sharing. PMID:27087759

Ethnicity and Race: Creating Educational Opportunities around the Globe. International Advances in Education: Global Initiatives for Equity and Social Justice

ERIC Educational Resources Information Center

Brown, Elinor L., Ed.; Gibbons, Pamela E., Ed.

2011-01-01

This volume of Global Initiatives for Equity and Social Justice takes a resource perspective toward culture, ethnicity, and race. Its purpose is to foster global dialog about race and ethnicity, with an emphasis on sharing strategies and solutions. While one might view problems stemming from racial and ethnic differences as intractable, the book's…

The global wilderness seminar for government agencies: a meeting at the crossroads of wildlands stewardship

Treesearch

Nancy Roeper; Peter Landres; Don Fisher

2006-01-01

Two days before the 8th World Wilderness Congress began in Alaska, nearly 200 government wildlands managers from 17 countries met to share ideas about common challenges and to explore ways to improve wildland stewardship globally. The goal for this Global Wilderness Seminar for Government Agencies was to lay the foundation for an operating peer network of government...

Building Global Support for Open Data Access

NASA Astrophysics Data System (ADS)

Key, E.; Samors, R. J.; Seltzer, C. E.; Orr, B. J.

2017-12-01

The Belmont Forum, a global partnership of funding organizations, international science councils, and regional consortia is committed to the advancement of international transdisciplinary research providing knowledge for understanding, mitigating and adapting to global environmental change. The Forum is also committed to ensuring appropriate, recognizable credit is awarded to the creators of that data, each and every time it is used. At its 2015 plenary meeting, the Belmont Forum agreed on and adopted an open data policy and principles. The principles are designed to widen access to data and promote its long-term preservation in global change research; help improve data management and exploitation; coordinate and integrate disparate organizational and technical elements; fill critical global e-infrastructure gaps; share best practices; and foster new data literacy. To help implement the policy and principles, the Belmont Forum has established the e-Infrastructures and Data Management (e-I&DM) Initiative which will leverage existing knowledge and resources to illuminate achievable, reproducible systems for effective, sustainable data management practices. The overall objective of the e-I&DM Initiative is to provide advice and recommendations to the Belmont Forum member and partner organizations regarding policies, programs, procedures that could be adopted to accelerate open data sharing, data reproducibility, data curation, and other aspects of long-term data management and access. This presentation will explore current Belmont Forum activities through the e-I&DM Initiative to develop policies and practices that could be adopted by funders, publishers and researchers alike that will lead to increased data sharing with more widespread data citation/attribution - giving credit where credit is due.

Global emergency medicine journal club: social media responses to the January 2014 online emergency medicine journal club on subarachnoid hemorrhage.

PubMed

Chan, Teresa M; Rosenberg, Hans; Lin, Michelle

2014-07-01

From January 20 to 24, 2014, Annals continued a successful collaboration with an academic Web site, Academic Life in Emergency Medicine (ALiEM), to host another Global Emergency Medicine Journal Club session featuring the 2013 Journal of the American Medical Association article "Clinical Decision Rules to Rule Out Subarachnoid Hemorrhage for Acute Headache" by Perry et al. This online journal club used the power of rapid Twitter conversations, a live videocast with the authors, and more detailed discussions hosted on the ALiEM Web site's comment section. There were more than 1,431 individuals from 501 cities in 59 countries who viewed the blog post. During this 5-day event, 28 comments (average word count 153 words) and 206 tweets were made. This summary article details the community discussion, shared insights, and analytic data generated during this novel, multiplatform approach. Copyright © 2014 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

Health issues in the Arab American community. Commentary on tobacco: the world's leading cause of cancer.

PubMed

Seffrin, John R

2007-01-01

Cancer incidence is on the rise in many regions of the world, including the Middle East, where incidence rates for both men and women are increasing. Like many regions of the world, increased tobacco use, combined with other factors, is driving cancer incidence in the Middle East. Tobacco, the only consumer product proven to kill more than half of its regular users, will be responsible for 4.9 million deaths worldwide this year alone. That burden is fairly evenly shared by industrialized and developing nations today but, if current trends continue, the cancer burden in the developing world will more than triple in the next 25 years, resulting in a global total of 10 million deaths worldwide each year. Seven million of these deaths will occur in the developing world, in nations least prepared to deal with the financial, social, and political consequences of this global public health tragedy. In the Arab world, lung cancer is already occurring with increasing frequency, particularly among men.

"Here nobody holds your heart": metaphoric and embodied emotions of birth and displacement among Karen women in Australia.

PubMed

Niner, Sara; Kokanovic, Renata; Cuthbert, Denise; Cho, Violet

2014-09-01

Our objective was to explore the ways in which displaced Karen mothers expressed emotions in narrative accounts of motherhood and displacement. We contextualized and analyzed interview data from an ethnographic study of birth and emotions among 15 displaced Karen mothers in Australia. We found that women shared a common symbolic language to describe emotions centered on the heart, which was also associated with heart "problems." This, along with hypertension, collapsing, or a feeling of surrender were associated responses to extremely adverse events experienced as displaced peoples. A metaphoric schema of emotional terms centered on the heart was connected to embodied expressions of emotion related to illness of the heart. This and other embodied responses were reactions to overwhelming difficulties and fear women endured due to their exposure to political conflict and global inequity. © 2014 by the American Anthropological Association.

Online Metadata Directories: A way of preserving, sharing and discovering scientific information

NASA Technical Reports Server (NTRS)

Meaux, M.

2005-01-01

The Global Change Master Directory (GCMD) assists the scientific community in the discovery of and linkage to Earth Science data and provides data holders a means to advertise their data to the community through its portals, i.e. online customized subset metadata directories. These directories are effectively serving communities like the Joint Committee on Antarctic Data Management (JCADM), the Global Observing System Information Center (GOSIC), and the Global Ocean Ecosystems Dynamic Program (GLOBEC) by increasing the visibility of their data holding. The purpose of the Gulf of Maine Ocean Data Partnership (GoMODP) is to "promote and coordinate the sharing, linking, electronic dissemination, and use of data on the Gulf of Maine region". The participants have decided that a "coordinated effort is needed to enable users throughout the Gulf of Maine region and beyond to discover and put to use the vast and growing quantities of data in their respective databases". GoMODP members have invited the GCMD to discuss potential collaborations associated with this effort. The presentation will focus on the use of the GCMD s metadata directory as a powerful tool for data discovery and sharing. An overview of the directory and its metadata authoring tools will be given.

Health is global: proposals for a UK Government-wide strategy.

PubMed

Donaldson, Liam; Banatvala, Nicholas

2007-03-10

Global health enables the harmonisation of international and domestic-health concerns-its outlook is much wider than a development or foreign-assistance perspective alone. Engaging globally in health requires the creation of relevant and effective partnerships to implement solutions for shared or common problems. To build on the UK's achievements and leadership in global health, the central government Department of Health is now leading the development of a UK Government-wide global strategy. This paper describes the rationale and process for developing the new UK Government-wide strategy for global health and highlights some of the issues that must be discussed.

Teaching Global Perspectives in a Rural Environment.

ERIC Educational Resources Information Center

Lind, Mary Ann

1980-01-01

Rural students can understand global perspectives by developing pride as food providers who share "kinship of the soil" with the developing world. Important lessons include man's dependence on the land; philosophy of environmental protection; agricultural technology; political influence over soil use; and five factors controlling crop production.…

Eduserv - the Education Service of Eurosdr: Sharing Experience for Capacity Building

NASA Astrophysics Data System (ADS)

Fritsch, D.; Mooney, K.; Oestman, A.

2012-07-01

This paper describes EduServ, the Education Service of EuroSDR - a European spatial data research organisation whose aim is to address the research needs of spatial data provision in Europe. With a current membership coming from seventeen European countries and a strong working relationship with related European organisations, EuroSDR has amassed considerable experience in addressing the extent and nature of this need. In order to facilitate the transfer of outcomes of EuroSDR research activities to the user domain, e.g. to key personnel in geographic information (GI) production organisations and industry, EuroSDR commenced this annual series of elearning courses in 2002. The Internet courses are preceded by a seminar at which participants meet tutors and receive guidelines for following the courses from their own locations. Delivery of the two-week courses requires an acceptable level of Internet connectivity, which exists in most member countries. EuroSDR is aware, however, that should such courses be shared internationally, other forms of communication will need to be addressed, such as satellite broadcasting. This would require effective collaboration with related organisations with experience with this means of communication. EduServ courses are offered in two successive years. During the courses, participants enjoy access to course tutors with a 24-hour response to queries guaranteed. Thereafter, course material for these courses is made available online. EuroSDR continues to work with past course tutors to ensure that this valuable resource is maintained as an effective and sustainable archive. This paper is aimed at sharing EuroSDR's experience in distance education with the wider scientific community with a view to its applicability to a global audience, whereby instead of sharing expertise within the GI community in Europe, European mapping agencies can share their knowledge and experience with the international GI community.

Job Sharing--Opportunities or Headaches?

ERIC Educational Resources Information Center

Leighton, Patricia

1986-01-01

Discusses the issue of job sharing as a new alternative available to workers. Topics covered include (1) a profile of job sharers, (2) response to job sharing, (3) establishing a job share, (4) job sharing in operation, and (5) legal analysis of job sharing. (CH)

76 FR 63811 - Structural Reforms To Improve the Security of Classified Networks and the Responsible Sharing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-13

... Structural Reforms To Improve the Security of Classified Networks and the Responsible Sharing and... classified national security information (classified information) on computer networks, it is hereby ordered as follows: Section 1. Policy. Our Nation's security requires classified information to be shared...

How ownership rights over microorganisms affect infectious disease control and innovation: A root-cause analysis of barriers to data sharing as experienced by key stakeholders.

PubMed

Ribeiro, Carolina Dos S; van Roode, Martine Y; Haringhuizen, George B; Koopmans, Marion P; Claassen, Eric; van de Burgwal, Linda H M

2018-01-01

Genetic information of pathogens is an essential input for infectious disease control, public health and for research. Efficiency in preventing and responding to global outbreaks relies on timely access to such information. Still, ownership barriers stand in the way of timely sharing of genetic data from pathogens, frustrating efficient public health responses and ultimately the potential use of such resources in innovations. Under a One Health approach, stakeholders, their interests and ownership issues are manifold and need to be investigated. We interviewed key actors from governmental and non-governmental bodies to identify overlapping and conflicting interests, and the overall challenges for sharing pathogen data, to provide essential inputs to the further development of political and practical strategies for improved data sharing practices. To identify and prioritize barriers, 52 Key Opinion Leaders were interviewed. A root-cause analysis was performed to identify causal relations between barriers. Finally, barriers were mapped to the innovation cycle reflecting how they affect the range of surveillance, innovation, and sharing activities. Four main barrier categories were found: compliance to regulations, negative consequences, self-interest, and insufficient incentives for compliance. When grouped in sectors (research institutes, public health organizations, supra-national organizations and industry) stakeholders appear to have similar interests, more than when grouped in domains (human, veterinary and food). Considering the innovation process, most of barriers could be mapped to the initial stages of the innovation cycle as sampling and sequencing phases. These are stages of primary importance to outbreak control and public health response. A minority of barriers applied to later stages in the innovation cycle, which are of more importance to product development. Overall, barriers are complex and entangled, due to the diversity of causal factors and their crosscutting features. Therefore, barriers must be addressed in a comprehensive and integrated manner. Stakeholders have different interests highlighting the diversity in motivations for sharing pathogen data: prioritization of public health, basic research, economic welfare and/or innovative capacity. Broad inter-sectorial discussions should start with the alignment of these interests within sectors. The improved sharing of pathogen data, especially in upstream phases of the innovation process, will generate substantial public health benefits through increased availability of data to inform surveillance systems, as well as to allow the (re-)use of data for the development of medical countermeasures to control infectious diseases.

How ownership rights over microorganisms affect infectious disease control and innovation: A root-cause analysis of barriers to data sharing as experienced by key stakeholders

PubMed Central

Haringhuizen, George B.; Koopmans, Marion P.; Claassen, Eric; van de Burgwal, Linda H. M.

2018-01-01

Background Genetic information of pathogens is an essential input for infectious disease control, public health and for research. Efficiency in preventing and responding to global outbreaks relies on timely access to such information. Still, ownership barriers stand in the way of timely sharing of genetic data from pathogens, frustrating efficient public health responses and ultimately the potential use of such resources in innovations. Under a One Health approach, stakeholders, their interests and ownership issues are manifold and need to be investigated. We interviewed key actors from governmental and non-governmental bodies to identify overlapping and conflicting interests, and the overall challenges for sharing pathogen data, to provide essential inputs to the further development of political and practical strategies for improved data sharing practices. Methods & findings To identify and prioritize barriers, 52 Key Opinion Leaders were interviewed. A root-cause analysis was performed to identify causal relations between barriers. Finally, barriers were mapped to the innovation cycle reflecting how they affect the range of surveillance, innovation, and sharing activities. Four main barrier categories were found: compliance to regulations, negative consequences, self-interest, and insufficient incentives for compliance. When grouped in sectors (research institutes, public health organizations, supra-national organizations and industry) stakeholders appear to have similar interests, more than when grouped in domains (human, veterinary and food). Considering the innovation process, most of barriers could be mapped to the initial stages of the innovation cycle as sampling and sequencing phases. These are stages of primary importance to outbreak control and public health response. A minority of barriers applied to later stages in the innovation cycle, which are of more importance to product development. Conclusion Overall, barriers are complex and entangled, due to the diversity of causal factors and their crosscutting features. Therefore, barriers must be addressed in a comprehensive and integrated manner. Stakeholders have different interests highlighting the diversity in motivations for sharing pathogen data: prioritization of public health, basic research, economic welfare and/or innovative capacity. Broad inter-sectorial discussions should start with the alignment of these interests within sectors. The improved sharing of pathogen data, especially in upstream phases of the innovation process, will generate substantial public health benefits through increased availability of data to inform surveillance systems, as well as to allow the (re-)use of data for the development of medical countermeasures to control infectious diseases. PMID:29718947

Seasonal and interannual variations of atmospheric CO2 and climate

NASA Astrophysics Data System (ADS)

Dettinger, Michael D.; Ghil, Michael

1998-02-01

Interannual variations of atmospheric CO2 concentrations at Mauna Loa are almost masked by the seasonal cycle and a strong trend; at the South Pole, the seasonal cycle is small and is almost lost in the trend and interannual variations. Singular-spectrum analysis (SSA) is used here to isolate and reconstruct interannual signals at both sites and to visualize recent decadal changes in the amplitude and phase of the seasonal cycle. Analysis of the Mauna Loa CO2 series illustrates a hastening of the CO2 seasonal cycle, a close temporal relation between Northern Hemisphere (NH) mean temperature trends and the amplitude of the seasonal CO2 cycle, and tentative ties between the latter and seasonality changes in temperature over the NH continents. Variations of the seasonal CO2 cycle at the South Pole differ from those at Mauna Loa: it is phase changes of the seasonal cycle at the South Pole, rather than amplitude changes, that parallel hemispheric and global temperature trends. The seasonal CO2 cycles exhibit earlier occurrences of the seasons by 7days at Mauna Loa and 18days at the South Pole. Interannual CO2 variations are shared at the two locations, appear to respond to tropical processes, and can be decomposed mostly into two periodicities, around (3years)1 and (4years)1, respectively. Joint SSA analyses of CO2 concentrations and tropical climate indices isolate a shared mode with a quasi-triennial (QT) period in which the CO2 and sea-surface temperature (SST) participation are in phase opposition. The other shared mode has a quasi-quadrennial (QQ) period and CO2 variations are in phase with the corresponding tropical SST variations throughout the tropics. Together these interannual modes exhibit a mean lag between tropical SSTs and CO2 variations of about 6 8months, with SST leading. Analysis of the QT and QQ signals in global gridded SSTs, joint SSA of CO2 and δ13C isotopic ratios, and SSA of CO2 and NH-land temperatures indicate that the QT variations in CO2 mostly reflect upwelling variations in the eastern tropical Pacific. QQ variations are dominated by the CO2 signature of terrestrial-ecosystem response to global QQ climate variations. Climate variations associated with these two interannual components of tropical variability have very different effects on global climate and, especially, on terrestrial ecosystems and the carbon cycle.

Effects of short-term exposure to environmentally relevant concentrations of different pharmaceutical mixtures on the immune response of the pond snail Lymnaea stagnalis.

PubMed

Gust, M; Fortier, M; Garric, J; Fournier, M; Gagné, F

2013-02-15

Pharmaceuticals are pollutants of potential concern in the aquatic environment where they are commonly introduced as complex mixtures via municipal effluents. Many reports underline the effects of pharmaceuticals on immune system of non target species. Four drug mixtures were tested, and regrouped pharmaceuticals by main therapeutic use: psychiatric (venlafaxine, carbamazepine, diazepam), antibiotic (ciprofloxacine, erythromycin, novobiocin, oxytetracycline, sulfamethoxazole, trimethoprim), hypolipemic (atorvastatin, gemfibrozil, benzafibrate) and antihypertensive (atenolol, furosemide, hydrochlorothiazide, lisinopril). Their effects were then compared with a treated municipal effluent known for its contamination, and its effects on the immune response of Lymnaea stagnalis. Adult L. stagnalis were exposed for 3 days to an environmentally relevant concentration of the four mixtures individually and as a global mixture. Effects on immunocompetence (hemocyte viability and count, ROS and thiol levels, phagocytosis) and gene expression were related to the immune response and oxidative stress: catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR), Selenium-dependent glutathione peroxidase (SeGPx), two isoforms of the nitric oxide synthetase gene (NOS1 and NOS2), molluscan defensive molecule (MDM), Toll-like receptor 4 (TLR4), allograft inflammatory factor-1 (AIF) and heat-shock protein 70 (HSP70). Immunocompetence was differently affected by the therapeutic class mixtures compared to the global mixture, which increased hemocyte count, ROS levels and phagocytosis, and decreased intracellular thiol levels. TLR4 gene expression was the most strongly increased, especially by psychiatric mixture (19-fold), while AIF-1, GR and CAT genes were downregulated. A decision tree analysis revealed that the immunotoxic responses caused by the municipal effluent were comparable to those obtained with the global pharmaceutical mixture, and the latter shared similarity with the antibiotic mixture. This suggests that pharmaceutical mixtures in municipal effluents represent a risk for gastropods at the immunocompetence levels and the antibiotic group could represent a model therapeutic class for municipal effluent toxicity studies in L. stagnalis. Copyright © 2013 Elsevier B.V. All rights reserved.

Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts.

PubMed

Yokoyama, Yoshie; Jelenkovic, Aline; Hur, Yoon-Mi; Sund, Reijo; Fagnani, Corrado; Stazi, Maria A; Brescianini, Sonia; Ji, Fuling; Ning, Feng; Pang, Zengchang; Knafo-Noam, Ariel; Mankuta, David; Abramson, Lior; Rebato, Esther; Hopper, John L; Cutler, Tessa L; Saudino, Kimberly J; Nelson, Tracy L; Whitfield, Keith E; Corley, Robin P; Huibregtse, Brooke M; Derom, Catherine A; Vlietinck, Robert F; Loos, Ruth J F; Llewellyn, Clare H; Fisher, Abigail; Bjerregaard-Andersen, Morten; Beck-Nielsen, Henning; Sodemann, Morten; Krueger, Robert F; McGue, Matt; Pahlen, Shandell; Bartels, Meike; van Beijsterveldt, Catharina E M; Willemsen, Gonneke; Harris, Jennifer R; Brandt, Ingunn; Nilsen, Thomas S; Craig, Jeffrey M; Saffery, Richard; Dubois, Lise; Boivin, Michel; Brendgen, Mara; Dionne, Ginette; Vitaro, Frank; Haworth, Claire M A; Plomin, Robert; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Rasmussen, Finn; Tynelius, Per; Tarnoki, Adam D; Tarnoki, David L; Ooki, Syuichi; Rose, Richard J; Pietiläinen, Kirsi H; Sørensen, Thorkild I A; Boomsma, Dorret I; Kaprio, Jaakko; Silventoinen, Karri

2018-05-19

The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia) and across birth cohorts, and how gestational age modifies these effects. Data from 26 twin cohorts in 16 countries including 57 613 monozygotic and dizygotic twin pairs were pooled. Genetic and environmental variations of birth size were estimated using genetic structural equation modelling. The variance of birthweight and length was predominantly explained by shared environmental factors, whereas the variance of PI was explained both by shared and unique environmental factors. Genetic variance contributing to birth size was small. Adjusting for gestational age decreased the proportions of shared environmental variance and increased the propositions of unique environmental variance. Genetic variance was similar in the geographical-cultural regions, but shared environmental variance was smaller in East Asia than in Europe and North America and Australia. The total variance and shared environmental variance of birth length and PI were greater from the birth cohort 1990-99 onwards compared with the birth cohorts from 1970-79 to 1980-89. The contribution of genetic factors to birth size is smaller than that of shared environmental factors, which is partly explained by gestational age. Shared environmental variances of birth length and PI were greater in the latest birth cohorts and differed also across geographical-cultural regions. Shared environmental factors are important when explaining differences in the variation of birth size globally and over time.

The social and ecological transitions of shrinking cities -- San Juan, Puerto Rico as a case study

EPA Science Inventory

Urban populations continue to increase globally and cities have become the dominant human habitat. However, the growth of cities is not universal. One in six cities globally is losing population. Shrinking cities share common attributes such as decreased household income, reduced...

Beginning the Assessment Institute and Building Global Networks

ERIC Educational Resources Information Center

Culver, Steven M.; Kniola, David

2013-01-01

The globalization of science and scholarship and the worldwide massification of post-secondary/tertiary education is creating an atmosphere that is at once competitive between and collaborative among colleges and universities. Because of the importance of these institutions to the shared economic futures of individuals and countries, there are…

78 FR 3477 - International Mail Contracts

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-16

... they share similar cost and market characteristics. Id. at 5. It notes that the pricing formula and...-filed Postal Service request concerning an additional Global Plus 2C contract. This document invites... announcing that it is entering into an additional Global Plus 2C contract (Agreement).\\1\\ The Postal Service...

Fostering Global Citizenship Education for Teachers through Online Research

ERIC Educational Resources Information Center

Harshman, Jason R.; Augustine, Tami A.

2013-01-01

This article is based on a study involving 126 International Baccalaureate (IB) teachers in more than 30 countries who, through the use of asynchronous online discussion forums, shared how they teach and simultaneously reflected upon how they conceptualize global citizenship. Data analysis revealed that participants developed new understandings…

Negotiating Global and Interdisciplinary Imperatives for Indigenous Education Scholarship and Pedagogy

ERIC Educational Resources Information Center

Charles, Harvey; Harris, Michelle; Carlson, Bronwyn

2016-01-01

Indigenous Studies is a rapidly growing field of enquiry both nationally and internationally. The internationalisation of the discipline is dependent on its interdiciplinarity and on the collaborative efforts of interdisciplinary scholars. Colonised Indigenous people globally share similar experiences despite differences in histories and contexts.…

Strategic Bridge Towards Community Building: The Military’s Role

DTIC Science & Technology

2008-03-24

matched easily by much of government—to address in its own way some significant domestic and global issues not normally associated with the private...wide-range of global issues and shared concerns, but there are other examples of strategic bridge organizations in recent years as well. The U.S

Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approach

PubMed Central

You, Sungyong; Yoo, Seung-Ah; Choi, Susanna; Kim, Ji-Young; Park, Su-Jung; Ji, Jong Dae; Kim, Tae-Hwan; Kim, Ki-Jo; Cho, Chul-Soo; Hwang, Daehee; Kim, Wan-Uk

2014-01-01

Rheumatoid synoviocytes, which consist of fibroblast-like synoviocytes (FLSs) and synovial macrophages (SMs), are crucial for the progression of rheumatoid arthritis (RA). Particularly, FLSs of RA patients (RA-FLSs) exhibit invasive characteristics reminiscent of cancer cells, destroying cartilage and bone. RA-FLSs and SMs originate differently from mesenchymal and myeloid cells, respectively, but share many pathologic functions. However, the molecular signatures and biological networks representing the distinct and shared features of the two cell types are unknown. We performed global transcriptome profiling of FLSs and SMs obtained from RA and osteoarthritis patients. By comparing the transcriptomes, we identified distinct molecular signatures and cellular processes defining invasiveness of RA-FLSs and proinflammatory properties of RA-SMs, respectively. Interestingly, under the interleukin-1β (IL-1β)–stimulated condition, the RA-FLSs newly acquired proinflammatory signature dominant in RA-SMs without losing invasive properties. We next reconstructed a network model that delineates the shared, RA-FLS–dominant (invasive), and RA-SM–dominant (inflammatory) processes. From the network model, we selected 13 genes, including periostin, osteoblast-specific factor (POSTN) and twist basic helix–loop–helix transcription factor 1 (TWIST1), as key regulator candidates responsible for FLS invasiveness. Of note, POSTN and TWIST1 expressions were elevated in independent RA-FLSs and further instigated by IL-1β. Functional assays demonstrated the requirement of POSTN and TWIST1 for migration and invasion of RA-FLSs stimulated with IL-1β. Together, our systems approach to rheumatoid synovitis provides a basis for identifying key regulators responsible for pathological features of RA-FLSs and -SMs, demonstrating how a certain type of cells acquires functional redundancy under chronic inflammatory conditions. PMID:24374632

Developing a curriculum framework for global health in family medicine: emerging principles, competencies, and educational approaches.

PubMed

Redwood-Campbell, Lynda; Pakes, Barry; Rouleau, Katherine; MacDonald, Colla J; Arya, Neil; Purkey, Eva; Schultz, Karen; Dhatt, Reena; Wilson, Briana; Hadi, Abdullahel; Pottie, Kevin

2011-07-22

Recognizing the growing demand from medical students and residents for more comprehensive global health training, and the paucity of explicit curricula on such issues, global health and curriculum experts from the six Ontario Family Medicine Residency Programs worked together to design a framework for global health curricula in family medicine training programs. A working group comprised of global health educators from Ontario's six medical schools conducted a scoping review of global health curricula, competencies, and pedagogical approaches. The working group then hosted a full day meeting, inviting experts in education, clinical care, family medicine and public health, and developed a consensus process and draft framework to design global health curricula. Through a series of weekly teleconferences over the next six months, the framework was revised and used to guide the identification of enabling global health competencies (behaviours, skills and attitudes) for Canadian Family Medicine training. The main outcome was an evidence-informed interactive framework http://globalhealth.ennovativesolution.com/ to provide a shared foundation to guide the design, delivery and evaluation of global health education programs for Ontario's family medicine residency programs. The curriculum framework blended a definition and mission for global health training, core values and principles, global health competencies aligning with the Canadian Medical Education Directives for Specialists (CanMEDS) competencies, and key learning approaches. The framework guided the development of subsequent enabling competencies. The shared curriculum framework can support the design, delivery and evaluation of global health curriculum in Canada and around the world, lay the foundation for research and development, provide consistency across programmes, and support the creation of learning and evaluation tools to align with the framework. The process used to develop this framework can be applied to other aspects of residency curriculum development.

Developing a curriculum framework for global health in family medicine: emerging principles, competencies, and educational approaches

PubMed Central

2011-01-01

Background Recognizing the growing demand from medical students and residents for more comprehensive global health training, and the paucity of explicit curricula on such issues, global health and curriculum experts from the six Ontario Family Medicine Residency Programs worked together to design a framework for global health curricula in family medicine training programs. Methods A working group comprised of global health educators from Ontario's six medical schools conducted a scoping review of global health curricula, competencies, and pedagogical approaches. The working group then hosted a full day meeting, inviting experts in education, clinical care, family medicine and public health, and developed a consensus process and draft framework to design global health curricula. Through a series of weekly teleconferences over the next six months, the framework was revised and used to guide the identification of enabling global health competencies (behaviours, skills and attitudes) for Canadian Family Medicine training. Results The main outcome was an evidence-informed interactive framework http://globalhealth.ennovativesolution.com/ to provide a shared foundation to guide the design, delivery and evaluation of global health education programs for Ontario's family medicine residency programs. The curriculum framework blended a definition and mission for global health training, core values and principles, global health competencies aligning with the Canadian Medical Education Directives for Specialists (CanMEDS) competencies, and key learning approaches. The framework guided the development of subsequent enabling competencies. Conclusions The shared curriculum framework can support the design, delivery and evaluation of global health curriculum in Canada and around the world, lay the foundation for research and development, provide consistency across programmes, and support the creation of learning and evaluation tools to align with the framework. The process used to develop this framework can be applied to other aspects of residency curriculum development. PMID:21781319

The funding landscape for HIV in Asia and the Pacific

PubMed Central

Stuart, Robyn M; Lief, Eric; Donald, Braedon; Wilson, David; Wilson, David P

2015-01-01

Introduction Despite recent and robust economic growth across the Asia-Pacific region, the majority of low- and middle-income countries in the region remain dependent on some donor support for HIV programmes. We describe the availability of bilateral and multilateral official development assistance (ODA) for HIV programmes in the region. Methods The donor countries considered in this analysis are Australia, Canada, Denmark, France, Germany, Netherlands, Norway, Sweden, the United Kingdom and the United States. To estimate bilateral and multilateral ODA financing for HIV programmes in the Asia-Pacific region between 2004 and 2013, we obtained funding data from the Organisation for Economic Co-operation and Development Creditor Reporting System database. Where possible, we checked these amounts against the funding data available from government aid agencies. Estimates of multilateral ODA financing for HIV/AIDS were based on the country allocations announcement by the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) for the period 2014 to 2016. Results Countries in the Asia-Pacific region receive the largest share of aid for HIV from the Global Fund. Bilateral funding for HIV in the region has been relatively stable over the last decade and is projected to remain below 10% of the worldwide response to the epidemic. Bilateral donors continue to prioritize ODA for HIV to other regions, particularly sub-Saharan Africa; Australia is an exception in prioritizing the Asia-Pacific region, but the United States is the bilateral donor providing the greatest amount of assistance in the region. Funding from the Global Fund has increased consistently since 2005, reaching a total of US$1.2 billion for the Asia-Pacific region from 2014 to 2016. Conclusions Even with Global Fund allocations, countries in the Asia-Pacific region will not have enough resources to meet their epidemiological targets. Prevention funding is particularly vulnerable and requires greater domestic leadership and coordination. Bilateral donors are still crucially important in the response to HIV throughout the Asia-Pacific region. PMID:26578252

The funding landscape for HIV in Asia and the Pacific.

PubMed

Stuart, Robyn M; Lief, Eric; Donald, Braedon; Wilson, David; Wilson, David P

2015-01-01

Despite recent and robust economic growth across the Asia-Pacific region, the majority of low- and middle-income countries in the region remain dependent on some donor support for HIV programmes. We describe the availability of bilateral and multilateral official development assistance (ODA) for HIV programmes in the region. The donor countries considered in this analysis are Australia, Canada, Denmark, France, Germany, Netherlands, Norway, Sweden, the United Kingdom and the United States. To estimate bilateral and multilateral ODA financing for HIV programmes in the Asia-Pacific region between 2004 and 2013, we obtained funding data from the Organisation for Economic Co-operation and Development Creditor Reporting System database. Where possible, we checked these amounts against the funding data available from government aid agencies. Estimates of multilateral ODA financing for HIV/AIDS were based on the country allocations announcement by the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) for the period 2014 to 2016. Countries in the Asia-Pacific region receive the largest share of aid for HIV from the Global Fund. Bilateral funding for HIV in the region has been relatively stable over the last decade and is projected to remain below 10% of the worldwide response to the epidemic. Bilateral donors continue to prioritize ODA for HIV to other regions, particularly sub-Saharan Africa; Australia is an exception in prioritizing the Asia-Pacific region, but the United States is the bilateral donor providing the greatest amount of assistance in the region. Funding from the Global Fund has increased consistently since 2005, reaching a total of US$1.2 billion for the Asia-Pacific region from 2014 to 2016. Even with Global Fund allocations, countries in the Asia-Pacific region will not have enough resources to meet their epidemiological targets. Prevention funding is particularly vulnerable and requires greater domestic leadership and coordination. Bilateral donors are still crucially important in the response to HIV throughout the Asia-Pacific region.

77 FR 30341 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-22

... procedures designed to prevent the use and dissemination of material non-public information regarding such... Intermarket Surveillance Group (``ISG''), which includes all U.S. national securities exchanges and certain... throughout the world. Global shares are the actual (ordinary) shares of a non-U.S. company which trade both...

Distribution and Causes of Global Forest Fragmentation

Treesearch

Timothy G. Wade; Kurt H. Riitters; James D. Wickham; K. Bruce Jones

2003-01-01

Abstract Because human land uses tend to expand over time, forests that share a high proportion of their borders with anthropogenic uses are at higher risk of further degradation than forests that share a high proportion of their borders with non-forest, natural land cover (e.g., wetland). Using 1-km advanced very high resolution radiometer (AVHRR)...

Global flows of critical metals necessary for low-carbon technologies: the case of neodymium, cobalt, and platinum.

PubMed

Nansai, Keisuke; Nakajima, Kenichi; Kagawa, Shigemi; Kondo, Yasushi; Suh, Sangwon; Shigetomi, Yosuke; Oshita, Yuko

2014-01-01

This study, encompassing 231 countries and regions, quantifies the global transfer of three critical metals (neodymium, cobalt, and platinum) considered vital for low-carbon technologies by means of material flow analysis (MFA), using trade data (BACI) and the metal contents of trade commodities, resolving the optimization problem to ensure the material balance of the metals within each country and region. The study shows that in 2005 international trade led to global flows of 18.6 kt of neodymium, 154 kt of cobalt, and 402 t of platinum and identifies the main commodities and top 50 bilateral trade links embodying these metals. To explore the issue of consumption efficiency, the flows were characterized according to the technological level of each country or region and divided into three types: green ("efficient use"), yellow ("moderately efficient use"), and red ("inefficient use"). On this basis, the shares of green, yellow, and red flows in the aggregate global flow of Nd were found to be 1.2%, 98%, and 1.2%, respectively. For Co, the respective figures are 53%, 28%, and 19%, and for Pt 15%, 84%, and 0.87%. Furthermore, a simple indicator focusing on the composition of the three colored flows for each commodity was developed to identify trade commodities that should be prioritized for urgent technical improvement to reduce wasteful use of the metals. Based on the indicator, we discuss logical, strategic identification of the responsibilities and roles of the countries involved in the global flows.

Toward a global space exploration program: A stepping stone approach

NASA Astrophysics Data System (ADS)

Ehrenfreund, Pascale; McKay, Chris; Rummel, John D.; Foing, Bernard H.; Neal, Clive R.; Masson-Zwaan, Tanja; Ansdell, Megan; Peter, Nicolas; Zarnecki, John; Mackwell, Steve; Perino, Maria Antionetta; Billings, Linda; Mankins, John; Race, Margaret

2012-01-01

In response to the growing importance of space exploration in future planning, the Committee on Space Research (COSPAR) Panel on Exploration (PEX) was chartered to provide independent scientific advice to support the development of exploration programs and to safeguard the potential scientific assets of solar system objects. In this report, PEX elaborates a stepwise approach to achieve a new level of space cooperation that can help develop world-wide capabilities in space science and exploration and support a transition that will lead to a global space exploration program. The proposed stepping stones are intended to transcend cross-cultural barriers, leading to the development of technical interfaces and shared legal frameworks and fostering coordination and cooperation on a broad front. Input for this report was drawn from expertise provided by COSPAR Associates within the international community and via the contacts they maintain in various scientific entities. The report provides a summary and synthesis of science roadmaps and recommendations for planetary exploration produced by many national and international working groups, aiming to encourage and exploit synergies among similar programs. While science and technology represent the core and, often, the drivers for space exploration, several other disciplines and their stakeholders (Earth science, space law, and others) should be more robustly interlinked and involved than they have been to date. The report argues that a shared vision is crucial to this linkage, and to providing a direction that enables new countries and stakeholders to join and engage in the overall space exploration effort. Building a basic space technology capacity within a wider range of countries, ensuring new actors in space act responsibly, and increasing public awareness and engagement are concrete steps that can provide a broader interest in space exploration, worldwide, and build a solid basis for program sustainability. By engaging developing countries and emerging space nations in an international space exploration program, it will be possible to create a critical bottom-up support structure to support program continuity in the development and execution of future global space exploration frameworks. With a focus on stepping stones, COSPAR can support a global space exploration program that stimulates scientists in current and emerging spacefaring nations, and that will invite those in developing countries to participate—pursuing research aimed at answering outstanding questions about the origins and evolution of our solar system and life on Earth (and possibly elsewhere). COSPAR, in cooperation with national and international science foundations and space-related organizations, will advocate this stepping stone approach to enhance future cooperative space exploration efforts.

International Collaborative Research Partnerships: Blending Science with Management and Diplomacy.

PubMed

Lau, Chuen-Yen; Wang, Crystal; Orsega, Susan; Tramont, Edmund C; Koita, Ousmane; Polis, Michael A; Siddiqui, Sophia

2014-12-01

As globalization progressively connects and impacts the health of people across the world, collaborative research partnerships provide mutual advantages by sharing knowledge and resources to address locally and globally relevant scientific and public health questions. Partnerships undertaken for scientific research are similar to business collaborations in that they require attention to partner systems, whether local, international, political, academic, or non-academic. Scientists, like diplomats or entrepreneurs, are representatives of their field, culture, and country and become obligatory agents in health diplomacy. This role significantly influences current and future collaborations with not only the immediate partner but with other in country partners as well. Research partnerships need continuous evaluation of the collaboration's productivity, perspectives of all partners, and desired outcomes for success to avoid engaging in "research tourism", particularly in developing regions. International engagement is a cornerstone in addressing the impact of infectious diseases globally. Global partnerships are strategically aligned with national, partner and global health priorities and may be based on specific requests for assistance from the partnering country governments. Here we share experiences from select research collaborations to highlight principles that we have found key in building long-term relationships with collaborators and in meeting the aim to address scientific questions relevant to the host country and strategic global health initiatives.

International Collaborative Research Partnerships: Blending Science with Management and Diplomacy

PubMed Central

Lau, Chuen-Yen; Wang, Crystal; Orsega, Susan; Tramont, Edmund C; Koita, Ousmane; Polis, Michael A; Siddiqui, Sophia

2015-01-01

As globalization progressively connects and impacts the health of people across the world, collaborative research partnerships provide mutual advantages by sharing knowledge and resources to address locally and globally relevant scientific and public health questions. Partnerships undertaken for scientific research are similar to business collaborations in that they require attention to partner systems, whether local, international, political, academic, or non-academic. Scientists, like diplomats or entrepreneurs, are representatives of their field, culture, and country and become obligatory agents in health diplomacy. This role significantly influences current and future collaborations with not only the immediate partner but with other in country partners as well. Research partnerships need continuous evaluation of the collaboration’s productivity, perspectives of all partners, and desired outcomes for success to avoid engaging in “research tourism”, particularly in developing regions. International engagement is a cornerstone in addressing the impact of infectious diseases globally. Global partnerships are strategically aligned with national, partner and global health priorities and may be based on specific requests for assistance from the partnering country governments. Here we share experiences from select research collaborations to highlight principles that we have found key in building long-term relationships with collaborators and in meeting the aim to address scientific questions relevant to the host country and strategic global health initiatives. PMID:26225217

Parent and Adolescent Distribution of Responsibility for Diabetes Self-care: Links to Health Outcomes

PubMed Central

Reynolds, Kerry A.; Siminerio, Linda; Escobar, Oscar; Becker, Dorothy

2008-01-01

Objective To examine the relation of adolescent and parent responsibility distribution for diabetes self-care to psychological and physical health. Methods We interviewed children (mean age 12 years) annually for 3 years and asked parents to complete a questionnaire. Both reported how diabetes self-care was distributed in the family. Amount of responsibility held by the child only, the parent only, and shared between child and parent was calculated. Psychological distress, competence, and diabetes outcomes were assessed at each wave. Results In both cross-sectional and longitudinal (lagged) analyses, multilevel modeling showed that shared responsibility was consistently associated with better psychological health, good self-care behavior, and good metabolic control, whereas child and parent responsibility were not. In some cases, links of shared responsibility to health outcomes were stronger among older adolescents. Conclusions These findings highlight the importance of shared responsibility for diabetes self-care through early to middle adolescence. PMID:17848390

Technology, public policy and control of transboundary livestock diseases in our lifetimes.

PubMed

Breeze, R G

2006-04-01

There are no technological barriers to eliminating major transboundary livestock diseases. 'Elimination' means that diseases no longer threaten livestock in the developed world nor the livelihoods of hundreds of millions of small farmers elsewhere. The problem is not lack of technology but failure of public policy. Developed country policy should actively combat accidental and intentional introductions; protect livestock against future advanced biological weapons; minimise the economic impacts after introduction by any means; abandon mass slaughter as a control tool; engage in disease removal in pursuit of a global economic, societal, and environmental agenda; and make appropriate national and cooperative investments. This is the moment for policy change because transboundary livestock disease elimination now involves powerful government ministries outside ministries of agriculture that are concerned about disease threats from many sources. Change can acquire support from the public and many organisations with shared interests. New policy is needed to change the belief that government is solely responsible for excluding disease, responding to introductions, and compensating farmers for losses during eradication. Effective border control and domestic preparedness programmes depend upon government and industry working together with costs falling upon those responsible in the form of 'user fees'. Compensation for stock slaughtered during outbreak control should be covered by private insurance. Government and industry should share the costs of an effective surveillance, diagnostic and response system. Surveillance must achieve or approach real-time understanding of the disease situation at all stages and in all places and be accessible over the Internet by diverse government agencies and stakeholders in-country and abroad. Traditional responses must be abandoned because they encourage terrorism. Regulatory approval processes must be modernized because they cannot keep up with new technology.

Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.

PubMed

DeBerg, Hannah A; Zaidi, Mussaret B; Altman, Matthew C; Khaenam, Prasong; Gersuk, Vivian H; Campos, Freddy D; Perez-Martinez, Iza; Meza-Segura, Mario; Chaussabel, Damien; Banchereau, Jacques; Estrada-Garcia, Teresa; Linsley, Peter S

2018-01-01

Globally, diarrheal diseases are a leading cause of death in children under five and disproportionately affect children in developing countries. Children who contract diarrheal diseases are rarely screened to identify the etiologic agent due to time and cost considerations associated with pathogen-specific screening and hence pathogen-directed therapy is uncommon. The development of biomarkers to rapidly identify underlying pathogens could improve treatment options and clinical outcomes in childhood diarrheal diseases. Here, we perform RNA sequencing on blood samples collected from children evaluated in an emergency room setting with diarrheal disease where the pathogen(s) present are known. We determine host response gene signatures specific to Salmonella, Shigella and rotavirus, but not E. coli, infections that distinguish them from each other and from healthy controls. Specifically, we observed differential expression of genes related to chemokine receptors or inflammasome signaling in Shigella cases, such as CCR3, CXCR8, and NLRC4, and interferon response genes, such as IFI44 and OASL, in rotavirus cases. Our findings add insight into the host peripheral immune response to these pathogens, and suggest strategies and limitations for the use host response transcript signatures for diagnosing the etiologic agent of childhood diarrheal diseases.

Comparative metabolomics of drought acclimation in model and forage legumes.

PubMed

Sanchez, Diego H; Schwabe, Franziska; Erban, Alexander; Udvardi, Michael K; Kopka, Joachim

2012-01-01

Water limitation has become a major concern for agriculture. Such constraints reinforce the urgent need to understand mechanisms by which plants cope with water deprivation. We used a non-targeted metabolomic approach to explore plastic systems responses to non-lethal drought in model and forage legume species of the Lotus genus. In the model legume Lotus. japonicus, increased water stress caused gradual increases of most of the soluble small molecules profiled, reflecting a global and progressive reprogramming of metabolic pathways. The comparative metabolomic approach between Lotus species revealed conserved and unique metabolic responses to drought stress. Importantly, only few drought-responsive metabolites were conserved among all species. Thus we highlight a potential impediment to translational approaches that aim to engineer traits linked to the accumulation of compatible solutes. Finally, a broad comparison of the metabolic changes elicited by drought and salt acclimation revealed partial conservation of these metabolic stress responses within each of the Lotus species, but only few salt- and drought-responsive metabolites were shared between all. The implications of these results are discussed with regard to the current insights into legume water stress physiology. © 2011 Blackwell Publishing Ltd.

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.

PubMed

Carreras Puigvert, Jordi; von Stechow, Louise; Siddappa, Ramakrishnaiah; Pines, Alex; Bahjat, Mahnoush; Haazen, Lizette C J M; Olsen, Jesper V; Vrieling, Harry; Meerman, John H N; Mullenders, Leon H F; van de Water, Bob; Danen, Erik H J

2013-01-22

In pluripotent stem cells, DNA damage triggers loss of pluripotency and apoptosis as a safeguard to exclude damaged DNA from the lineage. An intricate DNA damage response (DDR) signaling network ensures that the response is proportional to the severity of the damage. We combined an RNA interference screen targeting all kinases, phosphatases, and transcription factors with global transcriptomics and phosphoproteomics to map the DDR in mouse embryonic stem cells treated with the DNA cross-linker cisplatin. Networks derived from canonical pathways shared in all three data sets were implicated in DNA damage repair, cell cycle and survival, and differentiation. Experimental probing of these networks identified a mode of DNA damage-induced Wnt signaling that limited apoptosis. Silencing or deleting the p53 gene demonstrated that genotoxic stress elicited Wnt signaling in a p53-independent manner. Instead, this response occurred through reduced abundance of Csnk1a1 (CK1α), a kinase that inhibits β-catenin. Together, our findings reveal a balance between p53-mediated elimination of stem cells (through loss of pluripotency and apoptosis) and Wnt signaling that attenuates this response to tune the outcome of the DDR.

Climate Model Diagnostic Analyzer

NASA Technical Reports Server (NTRS)

Lee, Seungwon; Pan, Lei; Zhai, Chengxing; Tang, Benyang; Kubar, Terry; Zhang, Zia; Wang, Wei

2015-01-01

The comprehensive and innovative evaluation of climate models with newly available global observations is critically needed for the improvement of climate model current-state representation and future-state predictability. A climate model diagnostic evaluation process requires physics-based multi-variable analyses that typically involve large-volume and heterogeneous datasets, making them both computation- and data-intensive. With an exploratory nature of climate data analyses and an explosive growth of datasets and service tools, scientists are struggling to keep track of their datasets, tools, and execution/study history, let alone sharing them with others. In response, we have developed a cloud-enabled, provenance-supported, web-service system called Climate Model Diagnostic Analyzer (CMDA). CMDA enables the physics-based, multivariable model performance evaluations and diagnoses through the comprehensive and synergistic use of multiple observational data, reanalysis data, and model outputs. At the same time, CMDA provides a crowd-sourcing space where scientists can organize their work efficiently and share their work with others. CMDA is empowered by many current state-of-the-art software packages in web service, provenance, and semantic search.

Three Essays on Law Enforcement and Emergency Response Information Sharing and Collaboration: An Insider Perspective

ERIC Educational Resources Information Center

Treglia, Joseph V.

2013-01-01

This dissertation identifies what may be done to overcome barriers to information sharing among federal, tribal, state, and local law enforcement agencies and emergency responders. Social, technical, and policy factors related to information sharing and collaboration in the law enforcement and emergency response communities are examined. This…

Data Mining Approaches for Genomic Biomarker Development: Applications Using Drug Screening Data from the Cancer Genome Project and the Cancer Cell Line Encyclopedia.

PubMed

Covell, David G

2015-01-01

Developing reliable biomarkers of tumor cell drug sensitivity and resistance can guide hypothesis-driven basic science research and influence pre-therapy clinical decisions. A popular strategy for developing biomarkers uses characterizations of human tumor samples against a range of cancer drug responses that correlate with genomic change; developed largely from the efforts of the Cancer Cell Line Encyclopedia (CCLE) and Sanger Cancer Genome Project (CGP). The purpose of this study is to provide an independent analysis of this data that aims to vet existing and add novel perspectives to biomarker discoveries and applications. Existing and alternative data mining and statistical methods will be used to a) evaluate drug responses of compounds with similar mechanism of action (MOA), b) examine measures of gene expression (GE), copy number (CN) and mutation status (MUT) biomarkers, combined with gene set enrichment analysis (GSEA), for hypothesizing biological processes important for drug response, c) conduct global comparisons of GE, CN and MUT as biomarkers across all drugs screened in the CGP dataset, and d) assess the positive predictive power of CGP-derived GE biomarkers as predictors of drug response in CCLE tumor cells. The perspectives derived from individual and global examinations of GEs, MUTs and CNs confirm existing and reveal unique and shared roles for these biomarkers in tumor cell drug sensitivity and resistance. Applications of CGP-derived genomic biomarkers to predict the drug response of CCLE tumor cells finds a highly significant ROC, with a positive predictive power of 0.78. The results of this study expand the available data mining and analysis methods for genomic biomarker development and provide additional support for using biomarkers to guide hypothesis-driven basic science research and pre-therapy clinical decisions.

An integrated assessment modeling framework for uncertainty studies in global and regional climate change: the MIT IGSM-CAM (version 1.0)

NASA Astrophysics Data System (ADS)

Monier, E.; Scott, J. R.; Sokolov, A. P.; Forest, C. E.; Schlosser, C. A.

2013-12-01

This paper describes a computationally efficient framework for uncertainty studies in global and regional climate change. In this framework, the Massachusetts Institute of Technology (MIT) Integrated Global System Model (IGSM), an integrated assessment model that couples an Earth system model of intermediate complexity to a human activity model, is linked to the National Center for Atmospheric Research (NCAR) Community Atmosphere Model (CAM). Since the MIT IGSM-CAM framework (version 1.0) incorporates a human activity model, it is possible to analyze uncertainties in emissions resulting from both uncertainties in the underlying socio-economic characteristics of the economic model and in the choice of climate-related policies. Another major feature is the flexibility to vary key climate parameters controlling the climate system response to changes in greenhouse gases and aerosols concentrations, e.g., climate sensitivity, ocean heat uptake rate, and strength of the aerosol forcing. The IGSM-CAM is not only able to realistically simulate the present-day mean climate and the observed trends at the global and continental scale, but it also simulates ENSO variability with realistic time scales, seasonality and patterns of SST anomalies, albeit with stronger magnitudes than observed. The IGSM-CAM shares the same general strengths and limitations as the Coupled Model Intercomparison Project Phase 3 (CMIP3) models in simulating present-day annual mean surface temperature and precipitation. Over land, the IGSM-CAM shows similar biases to the NCAR Community Climate System Model (CCSM) version 3, which shares the same atmospheric model. This study also presents 21st century simulations based on two emissions scenarios (unconstrained scenario and stabilization scenario at 660 ppm CO2-equivalent) similar to, respectively, the Representative Concentration Pathways RCP8.5 and RCP4.5 scenarios, and three sets of climate parameters. Results of the simulations with the chosen climate parameters provide a good approximation for the median, and the 5th and 95th percentiles of the probability distribution of 21st century changes in global mean surface air temperature from previous work with the IGSM. Because the IGSM-CAM framework only considers one particular climate model, it cannot be used to assess the structural modeling uncertainty arising from differences in the parameterization suites of climate models. However, comparison of the IGSM-CAM projections with simulations of 31 CMIP5 models under the RCP4.5 and RCP8.5 scenarios show that the range of warming at the continental scale shows very good agreement between the two ensemble simulations, except over Antarctica, where the IGSM-CAM overestimates the warming. This demonstrates that by sampling the climate system response, the IGSM-CAM, even though it relies on one single climate model, can essentially reproduce the range of future continental warming simulated by more than 30 different models. Precipitation changes projected in the IGSM-CAM simulations and the CMIP5 multi-model ensemble both display a large uncertainty at the continental scale. The two ensemble simulations show good agreement over Asia and Europe. However, the ranges of precipitation changes do not overlap - but display similar size - over Africa and South America, two continents where models generally show little agreement in the sign of precipitation changes and where CCSM3 tends to be an outlier. Overall, the IGSM-CAM provides an efficient and consistent framework to explore the large uncertainty in future projections of global and regional climate change associated with uncertainty in the climate response and projected emissions.

"Bicycles May Use Full Lane" Signage Communicates U.S. Roadway Rules and Increases Perception of Safety.

PubMed

Hess, George; Peterson, M Nils

2015-01-01

Many global challenges, including obesity, health care costs, and climate change, could be addressed in part by increasing the use of bicycles for transportation. Concern about the safety of bicycling on roadways is frequently cited as a deterrent to increasing bicycle use in the USA. The use of effective signage along roadways might help alleviate these concerns by increasing knowledge about the rights and duties of bicyclists and motorists, ideally reducing crashes. We administered a web-based survey, using Twitter for recruitment, to examine how well three US traffic control devices communicated the message that bicyclists are permitted in the center of the travel lane and do not have to "get out of the way" to allow motorists to pass without changing lanes: "Bicycles May Use Full Lane" and "Share the Road" signage, and Shared Lane Markings on the pavement. Each was compared to an unsigned roadway. We also asked respondents whether it was safe for a bicyclist to occupy the center of the travel lane. "Bicycles May Use Full Lane" signage was the most consistently comprehended device for communicating the message that bicyclists may occupy the travel lane and also increased perceptions of safety. "Share the Road" signage did not increase comprehension or perceptions of safety. Shared Lane Markings fell somewhere between. "Bicycles May Use Full Lane" signage showed notable increases in comprehension among novice bicyclists and private motor vehicle commuters, critical target audiences for efforts to promote bicycling in the USA. Although limited in scope, our survey results are indicative and suggest that Departments of Transportation consider replacing "Share the Road" with "Bicycles May Use Full Lane" signage, possibly combined with Shared Lane Markings, if the intent is to increase awareness of roadway rights and responsibilities. Further evaluation through virtual reality simulations and on-road experiments is merited.

“Bicycles May Use Full Lane” Signage Communicates U.S. Roadway Rules and Increases Perception of Safety

PubMed Central

2015-01-01

Many global challenges, including obesity, health care costs, and climate change, could be addressed in part by increasing the use of bicycles for transportation. Concern about the safety of bicycling on roadways is frequently cited as a deterrent to increasing bicycle use in the USA. The use of effective signage along roadways might help alleviate these concerns by increasing knowledge about the rights and duties of bicyclists and motorists, ideally reducing crashes. We administered a web-based survey, using Twitter for recruitment, to examine how well three US traffic control devices communicated the message that bicyclists are permitted in the center of the travel lane and do not have to “get out of the way” to allow motorists to pass without changing lanes: “Bicycles May Use Full Lane” and “Share the Road” signage, and Shared Lane Markings on the pavement. Each was compared to an unsigned roadway. We also asked respondents whether it was safe for a bicyclist to occupy the center of the travel lane. “Bicycles May Use Full Lane” signage was the most consistently comprehended device for communicating the message that bicyclists may occupy the travel lane and also increased perceptions of safety. “Share the Road” signage did not increase comprehension or perceptions of safety. Shared Lane Markings fell somewhere between. “Bicycles May Use Full Lane” signage showed notable increases in comprehension among novice bicyclists and private motor vehicle commuters, critical target audiences for efforts to promote bicycling in the USA. Although limited in scope, our survey results are indicative and suggest that Departments of Transportation consider replacing “Share the Road” with “Bicycles May Use Full Lane” signage, possibly combined with Shared Lane Markings, if the intent is to increase awareness of roadway rights and responsibilities. Further evaluation through virtual reality simulations and on-road experiments is merited. PMID:26317355

Scaling up the global nursing health workforce: contributions of an international organization.

PubMed

Rukholm, Ellen E; Stamler, Lynnette Leeseberg; Talbot, Lise R; Bednash, Geraldine; Raines, Fay; Potempa, Kathleen; Nugent, Pauline; Clark, Dame Jill Macleod; Bernhauser, Sue; Parfitt, Barbara

2009-01-01

In this paper key highlights of the scholarly work presented at the Toronto 2008 Global Alliance for Nursing Education & Scholarship (GANES) conference are summarized, challenges opportunities and issues facing nursing education globally arising from the conference discourse are outlined and initial steps are suggested as a way forward to a shared global view of baccalaureate and graduate nursing education and scholarship. This shared view arises from beginning understandings of the issues and opportunities we face globally starting with and building upon the lessons learned from the literature and from the experiences of nursing educators and nursing education organization locally, regionally, nationally and internationally. The theme of the groundbreaking GANES Toronto conference was "Educating the future nursing and health workforce: A global challenge". One hundred seventy delegates from 17 countries attended the event, with over 80 papers presented. A primary focus of GANES is the contribution of a strategic alliance of national nursing education organizations to contribute to nursing education leading practices and policy that address the scaling up of global nursing and health workforce. The founding members of GANES see a clear link between a strong educational infrastructure and strong scholarship activities in nursing and the ability of a society to be healthy and prosperous. Evidence presented at the recent GANES conference supports that belief. Through the strength of partnerships and other capacity-building efforts, member countries can support each other to address the global nursing education and health challenges while respecting the local issues.

Activity level in the lab: Overlap with shyness indicates it is more than pure motoric activity.

PubMed

Frazier-Wood, Alexis C; Saudino, Kimberly J

2017-09-01

The observation that children's activity level (AL) differs between novel and familiar situations is well established. What influences individual differences in how AL is different across these situations is less well understood. Drawing on animal literature, which links rats' AL when 1st placed in a novel setting with novelty seeking phenotypes, and child temperament literature, which links AL, novelty response, and shyness, we hypothesized that shyness would be an important component of children's AL in a novel situation. We examined this using mechanically assessed AL from 2 situations (the home and the lab) and 2 measures of shyness (1 parent-rated and 1 observer-rated) on up to 313 twin pairs (145 monozygotic and 168 dizygotic), at 2 and 3 years of age. Biometric genetic models removed from lab AL the variance shared with home AL, representing what was different in AL when the child entered the lab compared to the home. We report that almost half (43%) of the genetic component of AL in the lab was independent of AL in the home, and this unique genetic component shared genetic covariance with shyness. Shyness influences AL in a novel situation such as the lab, indicating that mechanically assessed AL represents more than global motoric activity and provides information on a child's temperamental response to novelty. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Forecast-based Integrated Flood Detection System for Emergency Response and Disaster Risk Reduction (Flood-FINDER)

NASA Astrophysics Data System (ADS)

Arcorace, Mauro; Silvestro, Francesco; Rudari, Roberto; Boni, Giorgio; Dell'Oro, Luca; Bjorgo, Einar

2016-04-01

Most flood prone areas in the globe are mainly located in developing countries where making communities more flood resilient is a priority. Despite different flood forecasting initiatives are now available from academia and research centers, what is often missing is the connection between the timely hazard detection and the community response to warnings. In order to bridge the gap between science and decision makers, UN agencies play a key role on the dissemination of information in the field and on capacity-building to local governments. In this context, having a reliable global early warning system in the UN would concretely improve existing in house capacities for Humanitarian Response and the Disaster Risk Reduction. For those reasons, UNITAR-UNOSAT has developed together with USGS and CIMA Foundation a Global Flood EWS called "Flood-FINDER". The Flood-FINDER system is a modelling chain which includes meteorological, hydrological and hydraulic models that are accurately linked to enable the production of warnings and forecast inundation scenarios up to three weeks in advance. The system is forced with global satellite derived precipitation products and Numerical Weather Prediction outputs. The modelling chain is based on the "Continuum" hydrological model and risk assessments produced for GAR2015. In combination with existing hydraulically reconditioned SRTM data and 1D hydraulic models, flood scenarios are derived at multiple scales and resolutions. Climate and flood data are shared through a Web GIS integrated platform. First validation of the modelling chain has been conducted through a flood hindcasting test case, over the Chao Phraya river basin in Thailand, using multi temporal satellite-based analysis derived for the exceptional flood event of 2011. In terms of humanitarian relief operations, the EO-based services of flood mapping in rush mode generally suffer from delays caused by the time required for their activation, programming, acquisitions and image processing. Flood-FINDER aims to pre-empt this process and to provide preliminary analyses where no field data is available. In the early 2015, the Flood-FINDER's forecast along the Shire River has been used to guide the rapid mapping activities in Southern Malawi and Northern Mozambique. It proved efficient support providing timely information about the evolution of the flood event over an area lacking of field data. Regarding in-country capacity building, Flood-FINDER allowed UNOSAT to set up in middle 2015 a flood early warning system in Chad along the Chari River basin with the collaboration of Chadian Ministry of hydraulics and livestock. Weekly flood bulletins have been shared with local authorities and UN agencies over the entire rainy season. Finally, an experimental version of the global web alerting platform has been recently developed for supporting the El Nino flood preparedness in the Horn of Africa. Flood-FINDEŔs mission is to support decision makers throughout all the disaster management cycle with flood alerts, modelled scenarios, EO-based impact assessments and with direct support at country level to implement disaster mitigation strategies. The aim for the future is to seek funding for having the global system fully operational using CERN's supercomputing facilities and to establish new in-country projects with local authorities.

Negotiating the transition between different teaching contexts through shared responsibility and shared reflection

NASA Astrophysics Data System (ADS)

Beers, Jennifer S.

2009-06-01

This paper draws on my personal experiences with coteaching and my participation in the research described by Wassell and LaVan (2009). It examines the role of coteaching in the development of structures that afforded opportunities for shared reflection and shared responsibility between stakeholders in the classroom. It also describes how the schema and practices developed through coteaching and cogenerative dialogue helped mediate the transition between my preservice and inservice teaching experiences.

Perceptions of contraceptive responsibility among female college students: an exploratory study.

PubMed

Brunner Huber, Larissa R; Ersek, Jennifer L

2011-03-01

An important, although understudied, area related to contraceptive use is perceptions of contraceptive responsibility. The purpose of this exploratory study was to investigate these perceptions among female college students. Web-based or mailed questionnaires were completed by 326 students from 2006-2007. Logistic regression was used to obtain odds ratios and 95% confidence intervals (CI) to model the associations between select demographic and lifestyle characteristics and contraceptive responsibility (shared vs. individual responsibility). Although 89.1% of women felt that contraceptive responsibility should be shared, only 51.8% indicated that responsibility is actually shared in their relationships. After adjustment for age, race/ethnicity, marital status, and year of study, women using "other" methods of contraception (i.e. withdrawal, rhythm, sterilization, etc.) had 3.25 times the odds of stating that contraceptive responsibility is actually shared as compared to hormonal users (95% CI: 1.20, 8.80). For college women, there is a disconnect between who they feel should be responsible for contraception and who actually is responsible. Insight into perceptions of contraceptive responsibility in the university setting may help guide health educators and clinicians in designing pregnancy and sexually transmitted infection prevention programming. Copyright © 2011 Elsevier Inc. All rights reserved.

The U.S. Culture Collection Network Responding to the Requirements of the Nagoya Protocol on Access and Benefit Sharing

PubMed Central

Barker, Katharine B.; Barton, Hazel A.; Boundy-Mills, Kyria; Brown, Daniel R.; Coddington, Jonathan A.; Cook, Kevin; Desmeth, Philippe; Geiser, David; Glaeser, Jessie A.; Greene, Stephanie; Kang, Seogchan; Lomas, Michael W.; Melcher, Ulrich; Miller, Scott E.; Nobles, David R.; Owens, Kristina J.; Reichman, Jerome H.; da Silva, Manuela; Wertz, John; Whitworth, Cale; Smith, David

2017-01-01

ABSTRACT The U.S. Culture Collection Network held a meeting to share information about how culture collections are responding to the requirements of the recently enacted Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity (CBD). The meeting included representatives of many culture collections and other biological collections, the U.S. Department of State, U.S. Department of Agriculture, Secretariat of the CBD, interested scientific societies, and collection groups, including Scientific Collections International and the Global Genome Biodiversity Network. The participants learned about the policies of the United States and other countries regarding access to genetic resources, the definition of genetic resources, and the status of historical materials and genetic sequence information. Key topics included what constitutes access and how the CBD Access and Benefit-Sharing Clearing-House can help guide researchers through the process of obtaining Prior Informed Consent on Mutually Agreed Terms. U.S. scientists and their international collaborators are required to follow the regulations of other countries when working with microbes originally isolated outside the United States, and the local regulations required by the Nagoya Protocol vary by the country of origin of the genetic resource. Managers of diverse living collections in the United States described their holdings and their efforts to provide access to genetic resources. This meeting laid the foundation for cooperation in establishing a set of standard operating procedures for U.S. and international culture collections in response to the Nagoya Protocol. PMID:28811341

The U.S. Culture Collection Network Responding to the Requirements of the Nagoya Protocol on Access and Benefit Sharing.

PubMed

McCluskey, Kevin; Barker, Katharine B; Barton, Hazel A; Boundy-Mills, Kyria; Brown, Daniel R; Coddington, Jonathan A; Cook, Kevin; Desmeth, Philippe; Geiser, David; Glaeser, Jessie A; Greene, Stephanie; Kang, Seogchan; Lomas, Michael W; Melcher, Ulrich; Miller, Scott E; Nobles, David R; Owens, Kristina J; Reichman, Jerome H; da Silva, Manuela; Wertz, John; Whitworth, Cale; Smith, David

2017-08-15

The U.S. Culture Collection Network held a meeting to share information about how culture collections are responding to the requirements of the recently enacted Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization to the Convention on Biological Diversity (CBD). The meeting included representatives of many culture collections and other biological collections, the U.S. Department of State, U.S. Department of Agriculture, Secretariat of the CBD, interested scientific societies, and collection groups, including Scientific Collections International and the Global Genome Biodiversity Network. The participants learned about the policies of the United States and other countries regarding access to genetic resources, the definition of genetic resources, and the status of historical materials and genetic sequence information. Key topics included what constitutes access and how the CBD Access and Benefit-Sharing Clearing-House can help guide researchers through the process of obtaining Prior Informed Consent on Mutually Agreed Terms. U.S. scientists and their international collaborators are required to follow the regulations of other countries when working with microbes originally isolated outside the United States, and the local regulations required by the Nagoya Protocol vary by the country of origin of the genetic resource. Managers of diverse living collections in the United States described their holdings and their efforts to provide access to genetic resources. This meeting laid the foundation for cooperation in establishing a set of standard operating procedures for U.S. and international culture collections in response to the Nagoya Protocol.

A community effort to protect genomic data sharing, collaboration and outsourcing.

PubMed

Wang, Shuang; Jiang, Xiaoqian; Tang, Haixu; Wang, Xiaofeng; Bu, Diyue; Carey, Knox; Dyke, Stephanie Om; Fox, Dov; Jiang, Chao; Lauter, Kristin; Malin, Bradley; Sofia, Heidi; Telenti, Amalio; Wang, Lei; Wang, Wenhao; Ohno-Machado, Lucila

2017-01-01

The human genome can reveal sensitive information and is potentially re-identifiable, which raises privacy and security concerns about sharing such data on wide scales. In 2016, we organized the third Critical Assessment of Data Privacy and Protection competition as a community effort to bring together biomedical informaticists, computer privacy and security researchers, and scholars in ethical, legal, and social implications (ELSI) to assess the latest advances on privacy-preserving techniques for protecting human genomic data. Teams were asked to develop novel protection methods for emerging genome privacy challenges in three scenarios: Track (1) data sharing through the Beacon service of the Global Alliance for Genomics and Health. Track (2) collaborative discovery of similar genomes between two institutions; and Track (3) data outsourcing to public cloud services. The latter two tracks represent continuing themes from our 2015 competition, while the former was new and a response to a recently established vulnerability. The winning strategy for Track 1 mitigated the privacy risk by hiding approximately 11% of the variation in the database while permitting around 160,000 queries, a significant improvement over the baseline. The winning strategies in Tracks 2 and 3 showed significant progress over the previous competition by achieving multiple orders of magnitude performance improvement in terms of computational runtime and memory requirements. The outcomes suggest that applying highly optimized privacy-preserving and secure computation techniques to safeguard genomic data sharing and analysis is useful. However, the results also indicate that further efforts are needed to refine these techniques into practical solutions.

Measuring Up Internationally: Developing Skills and Knowledge for the Global Knowledge Economy. National Center Report #06-7

ERIC Educational Resources Information Center

Wagner, Alan

2006-01-01

Higher education globalizes: its potential contributions are now seen as a crucial component of cross-border economic competitiveness. Accumulating evidence suggests that a highly qualified workforce contributes substantially to a nation's economic competitiveness, particularly when a large share of the workforce has acquired skills and knowledge…

American Students Abroad Can't Be "Global Citizens"

ERIC Educational Resources Information Center

Zemach-Bersin, Talya

2008-01-01

A student shares experiences of her semester-long Tibetan-studies program in India, Nepal, and Tibet. Informed by both home university and program provider that by going abroad and immersing herself in a foreign culture, she would become a "global citizen," she was encouraged to "act like the locals," "be a resident,"…

"We Share the Same Biology..." Cultivating Cross-Cultural Empathy and Global Ethics through Multilingualism

ERIC Educational Resources Information Center

Rolbin, Cyrus; Chiesa, Bruno Della

2010-01-01

The "language-culture tesseract" hypothesized in the September 2010 issue of "Mind, Brain, and Education" suggests successive links between non-native language (NNL) acquisition, the development of cross-cultural empathy, and prosocial global ethics. Invoking Goethe's (1833/1999) aphorism, "those who do not know other languages know nothing of…

Periodicals Price Survey 2008: Embracing Openness

ERIC Educational Resources Information Center

Van Orsdel, Lee C.; Born, Kathleen

2008-01-01

Evidence for open access as an emergent, global state of mind is everywhere. The "New York Times" went "open" last September, and the "Wall Street Journal" is slated to follow. Increasingly, scholarly communities are breaking with tradition and calling for the open sharing of research, software, and data. Amongst these global initiatives is the…

Global Learning Communities: A Comparison of Online Domestic and International Science Class Partnerships

ERIC Educational Resources Information Center

Kerlin, Steven C.; Carlsen, William S.; Kelly, Gregory J.; Goehring, Elizabeth

2013-01-01

The conception of Global Learning Communities (GLCs) was researched to discover potential benefits of the use of online technologies that facilitated communication and scientific data sharing outside of the normal classroom setting. 1,419 students in 635 student groups began the instructional unit. Students represented the classrooms of 33…

Teach for All: Storytelling "Shared Solutions" and Scaling Global Reform

ERIC Educational Resources Information Center

Ahmann, Chloe

2015-01-01

"Teach For All" is a global network of state-based organizations that translate "Teach For America's" market model of school reform into moral projects of nation-building abroad. Referring to this challenge as one of "scaling" the organization, its leaders elaborate a theory of change that hinges on replicability: in…

Debriefing in Moodle: Written Feedback on Trust and Knowledge Sharing in a Social Dilemma Game

ERIC Educational Resources Information Center

Oertig, Margaret

2010-01-01

This article describes a new approach to debriefing that uses the discussion forum feature of the Moodle open source course management system to debrief a simulation game with undergraduate business students. The simulation game allowed the students to experience the fragility of trust when sharing knowledge in a global virtual project team. I…

75 FR 18554 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Amendment No. 1 and Order...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... Approval of a Proposed Rule Change, as Modified by Amendment No. 1 Thereto, Relating to the Listing of Mars...-4 thereunder,\\2\\ a proposed rule change to list and trade shares (``Shares'') of the Mars Hill... with ``Mars Hill Global Relative Value ETF'' and that all references in the filing to ``HTE Asset...

Do Librarians Have a Shared Set of Values? A Comparative Study of 36 Codes of Ethics Based on Gorman's "Enduring Values"

ERIC Educational Resources Information Center

Foster, Catherine; McMenemy, David

2012-01-01

Thirty-six ethical codes from national professional associations were studied, the aim to test whether librarians have global shared values or if political and cultural contexts have significantly influenced the codes' content. Gorman's eight core values of stewardship, service, intellectual freedom, rationalism, literacy and learning, equity of…

76 FR 4401 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-25

... Proposed Rule Change To Impose a Quarterly Maximum on the Listing of Additional Shares Fees Payable by... Terms of Substance of the Proposed Rule Change Nasdaq proposes to impose a quarterly maximum on the.... 5910. The NASDAQ Global Market (a) No change. (b) Additional Shares (1)-(5) No change. (6) The maximum...

Overexcitability and Optimal Flow in Talented Dancers, Singers, and Athletes

ERIC Educational Resources Information Center

Thomson, Paula; Jaque, S. Victoria

2016-01-01

Overexcitability (OE) and optimal flow are variables shared by talented individuals. This study demonstrated that the dancer (n = 86) and opera singer (n = 61) groups shared higher OE profiles compared to the athlete group (n = 50). Two self-report instruments assessed flow (global and subscales) and the five OE dimensions. All groups endorsed…

Responsibility-Sharing in the Giving and Receiving of Assessment Feedback

PubMed Central

Nash, Robert A.; Winstone, Naomi E.

2017-01-01

Many argue that effective learning requires students to take a substantial share of responsibility for their academic development, complementing the responsibilities taken by their educators. Yet this notion of responsibility-sharing receives minimal discussion in the context of assessment feedback, where responsibility for enhancing learning is often framed as lying principally with educators. Developing discussion on this issue is critical: many barriers can prevent students from engaging meaningfully with feedback, but neither educators nor students are fully empowered to remove these barriers without collaboration. In this discussion paper we argue that a culture of responsibility-sharing in the giving and receiving of feedback is essential, both for ensuring that feedback genuinely benefits students by virtue of their skilled and proactive engagement, and also for ensuring the sustainability of educators' effective feedback practices. We propose some assumptions that should underpin such a culture, and we consider the practicalities of engendering this cultural shift within modern higher education. PMID:28932202

Implementing efficient and sustainable collaboration between National Immunization Technical Advisory Groups: Report on the 3rd International Technical Meeting, Paris, France, 8-9 December 2014.

PubMed

Perronne, Christian; Adjagba, Alex; Duclos, Philippe; Floret, Daniel; Houweling, Hans; Le Goaster, Corinne; Lévy-Brühl, Daniel; Meyer, François; Senouci, Kamel; Wichmann, Ole

2016-03-08

Many experts on vaccination are convinced that efforts should be made to encourage increased collaboration between National Immunization Technical Advisory Groups on immunization (NITAGs) worldwide. International meetings were held in Berlin, Germany, in 2010 and 2011, to discuss improvement of the methodologies for the development of evidence-based vaccination recommendations, recognizing the need for collaboration and/or sharing of resources in this effort. A third meeting was held in Paris, France, in December 2014, to consider the design of specific practical activities and an organizational structure to enable effective and sustained collaboration. The following conclusions were reached: (i) The proposed collaboration needs a core functional structure and the establishment or strengthening of an international network of NITAGs. (ii) Priority subjects for collaborative work are background information for recommendations, systematic reviews, mathematical models, health economic evaluations and establishment of common frameworks and methodologies for reviewing and grading the evidence. (iii) The programme of collaborative work should begin with participation of a limited number of NITAGs which already have a high level of expertise. The amount of joint work could be increased progressively through practical activities and pragmatic examples. Due to similar priorities and already existing structures, this should be organized at regional or subregional level. For example, in the European Union a project is funded by the European Centre for Disease Prevention and Control (ECDC) with the aim to set up a network for improving data, methodology and resource sharing and thereby supporting NITAGs. Such regional networking activities should be carried out in collaboration with the World Health Organization (WHO). (iv) A global steering committee should be set up to promote international exchange between regional networks and to increase the involvement of less experienced NITAGs. NITAGs already collaborate at the global level via the NITAG Resource Centre, a web-based platform developed by the Health Policy and Institutional Development Unit (WHO Collaborating Centre) of the Agence de Médecine Préventive (AMP-HPID). It would be appropriate to continue facilitating the coordination of this global network through the AMP-HPID NITAG Resource Centre. (v) While sharing work products and experiences, each NITAG would retain responsibility for its own decision-making and country-specific recommendations. Copyright © 2016. Published by Elsevier Ltd.. All rights reserved.

Orbital pacing and ocean circulation-induced collapses of the Mesoamerican monsoon over the past 22,000 y.

PubMed

Lachniet, Matthew S; Asmerom, Yemane; Bernal, Juan Pablo; Polyak, Victor J; Vazquez-Selem, Lorenzo

2013-06-04

The dominant controls on global paleomonsoon strength include summer insolation driven by precession cycles, ocean circulation through its influence on atmospheric circulation, and sea-surface temperatures. However, few records from the summer North American Monsoon system are available to test for a synchronous response with other global monsoons to shared forcings. In particular, the monsoon response to widespread atmospheric reorganizations associated with disruptions of the Atlantic Meridional Overturning Circulation (AMOC) during the deglacial period remains unconstrained. Here, we present a high-resolution and radiometrically dated monsoon rainfall reconstruction over the past 22,000 y from speleothems of tropical southwestern Mexico. The data document an active Last Glacial Maximum (18-24 cal ka B.P.) monsoon with similar δ(18)O values to the modern, and that the monsoon collapsed during periods of weakened AMOC during Heinrich stadial 1 (ca. 17 ka) and the Younger Dryas (12.9-11.5 ka). The Holocene was marked by a trend to a weaker monsoon that was paced by orbital insolation. We conclude that the Mesoamerican monsoon responded in concert with other global monsoon regions, and that monsoon strength was driven by variations in the strength and latitudinal position of the Intertropical Convergence Zone, which was forced by AMOC variations in the North Atlantic Ocean. The surprising observation of an active Last Glacial Maximum monsoon is attributed to an active but shallow AMOC and proximity to the Intertropical Convergence Zone. The emergence of agriculture in southwestern Mexico was likely only possible after monsoon strengthening in the Early Holocene at ca. 11 ka.

Implementing One Health as an integrated approach to health in Rwanda.

PubMed

Nyatanyi, Thierry; Wilkes, Michael; McDermott, Haley; Nzietchueng, Serge; Gafarasi, Isidore; Mudakikwa, Antoine; Kinani, Jean Felix; Rukelibuga, Joseph; Omolo, Jared; Mupfasoni, Denise; Kabeja, Adeline; Nyamusore, Jose; Nziza, Julius; Hakizimana, Jean Leonard; Kamugisha, Julius; Nkunda, Richard; Kibuuka, Robert; Rugigana, Etienne; Farmer, Paul; Cotton, Philip; Binagwaho, Agnes

2017-01-01

It is increasingly clear that resolution of complex global health problems requires interdisciplinary, intersectoral expertise and cooperation from governmental, non-governmental and educational agencies. 'One Health' refers to the collaboration of multiple disciplines and sectors working locally, nationally and globally to attain optimal health for people, animals and the environment. One Health offers the opportunity to acknowledge shared interests, set common goals, and drive toward team work to benefit the overall health of a nation. As in most countries, the health of Rwanda's people and economy are highly dependent on the health of the environment. Recently, Rwanda has developed a One Health strategic plan to meet its human, animal and environmental health challenges. This approach drives innovations that are important to solve both acute and chronic health problems and offers synergy across systems, resulting in improved communication, evidence-based solutions, development of a new generation of systems-thinkers, improved surveillance, decreased lag time in response, and improved health and economic savings. Several factors have enabled the One Health movement in Rwanda including an elaborate network of community health workers, existing rapid response teams, international academic partnerships willing to look more broadly than at a single disease or population, and relative equity between female and male health professionals. Barriers to implementing this strategy include competition over budget, poor communication, and the need for improved technology. Given the interconnectedness of our global community, it may be time for countries and their neighbours to follow Rwanda's lead and consider incorporating One Health principles into their national strategic health plans.

Orbital pacing and ocean circulation-induced collapses of the Mesoamerican monsoon over the past 22,000 y

PubMed Central

Lachniet, Matthew S.; Asmerom, Yemane; Bernal, Juan Pablo; Polyak, Victor J.; Vazquez-Selem, Lorenzo

2013-01-01

The dominant controls on global paleomonsoon strength include summer insolation driven by precession cycles, ocean circulation through its influence on atmospheric circulation, and sea-surface temperatures. However, few records from the summer North American Monsoon system are available to test for a synchronous response with other global monsoons to shared forcings. In particular, the monsoon response to widespread atmospheric reorganizations associated with disruptions of the Atlantic Meridional Overturning Circulation (AMOC) during the deglacial period remains unconstrained. Here, we present a high-resolution and radiometrically dated monsoon rainfall reconstruction over the past 22,000 y from speleothems of tropical southwestern Mexico. The data document an active Last Glacial Maximum (18–24 cal ka B.P.) monsoon with similar δ18O values to the modern, and that the monsoon collapsed during periods of weakened AMOC during Heinrich stadial 1 (ca. 17 ka) and the Younger Dryas (12.9–11.5 ka). The Holocene was marked by a trend to a weaker monsoon that was paced by orbital insolation. We conclude that the Mesoamerican monsoon responded in concert with other global monsoon regions, and that monsoon strength was driven by variations in the strength and latitudinal position of the Intertropical Convergence Zone, which was forced by AMOC variations in the North Atlantic Ocean. The surprising observation of an active Last Glacial Maximum monsoon is attributed to an active but shallow AMOC and proximity to the Intertropical Convergence Zone. The emergence of agriculture in southwestern Mexico was likely only possible after monsoon strengthening in the Early Holocene at ca. 11 ka. PMID:23690596

Global Perspectives on Cancer Health Disparities: Impact, Utility, and Implications for Cancer Nursing

PubMed Central

So, Winnie K. W.; Chan, Raymond Javan; Truant, Tracy; Trevatt, Paul; Bialous, Stella Aguinaga; Barton-Burke, Margaret

2016-01-01

This paper examines cancer health disparities and contributing factors at national, regional, and international levels. The authors all live in different countries and regions with different health-care systems and practices. Despite the shared cancer nursing perspective, each country or global region approaches cancer disparities differently. With globalization the world is becoming smaller, and in turn becoming interconnected and interdependent. This article focuses on cancer health disparities and global cancer nursing, exemplifying these concepts about the impact and implications of person-centered care. PMID:28083548

CDISC SHARE, a Global, Cloud-based Resource of Machine-Readable CDISC Standards for Clinical and Translational Research

PubMed Central

Hume, Samuel; Chow, Anthony; Evans, Julie; Malfait, Frederik; Chason, Julie; Wold, J. Darcy; Kubick, Wayne; Becnel, Lauren B.

2018-01-01

The Clinical Data Interchange Standards Consortium (CDISC) is a global non-profit standards development organization that creates consensus-based standards for clinical and translational research. Several of these standards are now required by regulators for electronic submissions of regulated clinical trials’ data and by government funding agencies. These standards are free and open, available for download on the CDISC Website as PDFs. While these documents are human readable, they are not amenable to ready use by electronic systems. CDISC launched the CDISC Shared Health And Research Electronic library (SHARE) to provide the standards metadata in machine-readable formats to facilitate the automated management and implementation of the standards. This paper describes how CDISC SHARE’S standards can facilitate collecting, aggregating and analyzing standardized data from early design to end analysis; and its role as a central resource providing information systems with metadata that drives process automation including study setup and data pipelining. PMID:29888049

Design and development of an international clinical data exchange system: the international layer function of the Dolphin Project

PubMed Central

Zhou, Tian-shu; Chu, Jian; Araki, Kenji; Yoshihara, Hiroyuki

2011-01-01

Objective At present, most clinical data are exchanged between organizations within a regional system. However, people traveling abroad may need to visit a hospital, which would make international exchange of clinical data very useful. Background Since 2007, a collaborative effort to achieve clinical data sharing has been carried out at Zhejiang University in China and Kyoto University and Miyazaki University in Japan; each is running a regional clinical information center. Methods An international layer system named Global Dolphin was constructed with several key services, sharing patients' health information between countries using a medical markup language (MML). The system was piloted with 39 test patients. Results The three regions above have records for 966 000 unique patients, which are available through Global Dolphin. Data exchanged successfully from Japan to China for the 39 study patients include 1001 MML files and 152 images. The MML files contained 197 free text-type paragraphs that needed human translation. Discussion The pilot test in Global Dolphin demonstrates that patient information can be shared across countries through international health data exchange. To achieve cross-border sharing of clinical data, some key issues had to be addressed: establishment of a super directory service across countries; data transformation; and unique one—language translation. Privacy protection was also taken into account. The system is now ready for live use. Conclusion The project demonstrates a means of achieving worldwide accessibility of medical data, by which the integrity and continuity of patients' health information can be maintained. PMID:21571747

Rapid Protein Global Fold Determination Using Ultrasparse Sampling, High-Dynamic Range Artifact Suppression, and Time-Shared NOESY

PubMed Central

Coggins, Brian E.; Werner-Allen, Jonathan W.; Yan, Anthony; Zhou, Pei

2012-01-01

In structural studies of large proteins by NMR, global fold determination plays an increasingly important role in providing a first look at a target’s topology and reducing assignment ambiguity in NOESY spectra of fully-protonated samples. In this work, we demonstrate the use of ultrasparse sampling, a new data processing algorithm, and a 4-D time-shared NOESY experiment (1) to collect all NOEs in 2H/13C/15N-labeled protein samples with selectively-protonated amide and ILV methyl groups at high resolution in only four days, and (2) to calculate global folds from this data using fully automated resonance assignment. The new algorithm, SCRUB, incorporates the CLEAN method for iterative artifact removal, but applies an additional level of iteration, permitting real signals to be distinguished from noise and allowing nearly all artifacts generated by real signals to be eliminated. In simulations with 1.2% of the data required by Nyquist sampling, SCRUB achieves a dynamic range over 10000:1 (250× better artifact suppression than CLEAN) and completely quantitative reproduction of signal intensities, volumes, and lineshapes. Applied to 4-D time-shared NOESY data, SCRUB processing dramatically reduces aliasing noise from strong diagonal signals, enabling the identification of weak NOE crosspeaks with intensities 100× less than diagonal signals. Nearly all of the expected peaks for interproton distances under 5 Å were observed. The practical benefit of this method is demonstrated with structure calculations for 23 kDa and 29 kDa test proteins using the automated assignment protocol of CYANA, in which unassigned 4-D time-shared NOESY peak lists produce accurate and well-converged global fold ensembles, whereas 3-D peak lists either fail to converge or produce significantly less accurate folds. The approach presented here succeeds with an order of magnitude less sampling than required by alternative methods for processing sparse 4-D data. PMID:22946863

Global Science Share: Connecting young scientists from developing countries with science writing mentors to strengthen and widen the international science community

NASA Astrophysics Data System (ADS)

Hasenkopf, C. A.

2012-12-01

Collaborative science in which scientists are able to form research questions based on the current body of scientific knowledge and get feedback from colleagues on their ideas and work is essential for pushing science forward. However, not all scientists are able to fully participate in the international science community. Scientists from developing countries can face barriers to communicating with the international community due to, among other issues: fewer scientists in their home country, difficulty in getting language-specific science writing training, fewer established pre-existing international collaborations and networks, and sometimes geographic isolation. These barriers not only result in keeping individual scientists from contributing their ideas, but they also slow down the progress of the scientific enterprise for everyone. Global Science Share (http://globalscienceshare.org/) is a new project, entering its pilot phase in Fall 2012, which will work to reduce this disparity by connecting young scientists and engineers from developing countries seeking to improve their technical writing with other scientists and engineers around the world via online collaborations. Scientist-volunteers act as mentors and are paired up with mentees according to their academic field and writing needs. The mentors give feedback and constructive technical and editorial criticisms on mentees' submitted pieces of writing through a four-step email discussion. Mentees gain technical writing skills, as well as make international connections with other scientists and engineers in fields related to their own. Mentors also benefit by gaining new international scientific colleagues and honing their own writing skills through their critiques. The Global Science Share project will begin its pilot phase by first inviting Mongolian science students to apply as mentees this fall. This abstract will introduce the Global Science Share program, present a progress report from its first semester, and inform members of the geoscience community about this unique outreach opportunity to help strengthen and widen the international science community that can be done in the comfort of one's office or home.

Variations in "Party Line" Information Importance Between Pilots of Difference Characteristics

NASA Technical Reports Server (NTRS)

Pritchett, Amy R.; Hansman, R. John

1995-01-01

The introduction of digital datalink communications into the air traffic control (ATC) system may cause a reduction of the situation awareness of flight crews due to the reduction of 'Party Line' Information (PLI) that can be overheard on the shared voice frequencies. A survey was distributed to determine current PLI use by pilots from different geographic regions, operational groups, experience levels, and aircraft equipage. Pilots indicated highest perceived importance for PLI during the phases of flight nearest the airport and lowest importance during cruise. Several specific traffic and weather information elements were identified as particularly important; traffic and weather information was also cited by pilots as information required for global situation awareness. Some variations in responses were found between pilots from different operational types.

To promote adoption of household health technologies, think beyond health.

PubMed

Thurber, Mark C; Warner, Christina; Platt, Lauren; Slaski, Alexander; Gupta, Rajesh; Miller, Grant

2013-10-01

Health risks from poor malaria control, unsafe water, and indoor air pollution are responsible for an important share of the global disease burden-and they can be addressed by efficacious household health technologies that have existed for decades. However, coverage rates of these products among populations at risk remain disappointingly low. We conducted a review of the medical and public health literatures and found that health considerations alone are rarely sufficient motivation for households to adopt and use these technologies. In light of these findings, we argue that health education and persuasion campaigns by themselves are unlikely to be adequate. Instead, health policymakers and professionals must understand what users value beyond health and possibly reengineer health technologies with these concerns in mind.

To Promote Adoption of Household Health Technologies, Think Beyond Health

PubMed Central

Warner, Christina; Platt, Lauren; Slaski, Alexander; Gupta, Rajesh; Miller, Grant

2013-01-01

Health risks from poor malaria control, unsafe water, and indoor air pollution are responsible for an important share of the global disease burden—and they can be addressed by efficacious household health technologies that have existed for decades. However, coverage rates of these products among populations at risk remain disappointingly low. We conducted a review of the medical and public health literatures and found that health considerations alone are rarely sufficient motivation for households to adopt and use these technologies. In light of these findings, we argue that health education and persuasion campaigns by themselves are unlikely to be adequate. Instead, health policymakers and professionals must understand what users value beyond health and possibly reengineer health technologies with these concerns in mind. PMID:23948003

Shared Responsibility and Student Learning: Ensuring a Favorable Educational Experience

ERIC Educational Resources Information Center

Sierra, Jeremy J.

2010-01-01

In academia, interdependence or shared responsibility between instructor and student is an essential part of the educational process, yet research examining its effect on student responses toward their learning experience is scant. To offer insight into this context, two studies are developed. Study 1 finds that perceptions of shared…

Resource integration and shared outcomes at the watershed scale

Treesearch

Eleanor S. Towns

2000-01-01

Shared resources are universal resources that are vital for sustaining communities, enhancing our quality of life and preserving ecosystem health. We have a shared responsibility to conserve shared resources and preserve their integrity for future generations. Resource integration is accomplished through ecosystem management, often at a watershed scale. The shared...

AB052. The Human Variome Project (HVP) and the HVP ASEAN Node

PubMed Central

Alwi, Zilfalil Bin

2015-01-01

The Human Variome Project (HVP) is an international NGO that is working to build capacity in responsible clinical genomics around the world. Founded in 2006, and lead in its early years by Professor Richard Cotton, the Project has grown to become a global movement with over 1,300 individual members from 81 countries and close to 200 data provider members. The project works to ensure that the lack of access to information on genetic variants and their effects on human health is not an impediment to diagnosis and treatment. Together with partner organisations including national and regional human genetics societies, national governments and intergovernmental organisations such as UNESCO—of which the HVP is an NGO official partner—the project establishes standards, guidelines and best practices for the responsible development and operation of genetic variation data sharing infrastructure, facilitates training and education of the public and the clinical genomics field and assists in embedding data sharing into routine clinical practice. The HVP believes that the free and open sharing of genetic variation is fundamental to providing quality clinical care. To ensure that this data can be collected, curated, interpreted and shared in a responsible manner that is respectful of the diverse ethical, legal and social differences of its member countries, the HVP works with local stakeholders in each country to establish HVP Country Nodes. An HVP Country Node is defined as having three components: (I) a repository, or linked network of databases, that collect and store information on variation in the human genome that has been generated within each country and that enables the sharing of that information both nationally and internationally; (II) a governance structure that ensures that the work of the Node is both sustainable in the long term and is consistent with all relevant national and international ethical, legal and social requirements; and (III) a set of policies and procedures that ensures that the repository is operated and maintained in a responsible and accountable manner that is consistent with both national and HVP Standards. The HVP Malaysian Node (MyHVP), one of 23 HVP Country Nodes currently in existence, was established in 2010 and officially launched by Professor Cotton. The MyHVP database was made available on the internet a year later. The HVP Malaysian Node has taken a key role in the region and has worked to establish the HVP ASEAN Regional Node. Among its objectives is to foster closer collaboration among ASEAN member states on issues relating to data sharing, data basing and variant interpretation expertise, resources and technical facilities. The HVP ASEAN Regional Node also provides help with capacity building and training, especially to less well-resourced countries in the South East Asian region, for example Cambodia, Laos, and Myanmar. The HVP ASEAN Regional Node was launched in 2013 at Universiti Sains Malaysia, Kota Bharu, Malaysia. Representatives from Thailand, Vietnam, Singapore, Brunei, Indonesia, Philippines and the international Human Variome Project were represented. This presentation will provide an in-depth overview of the HVP ASEAN Regional Node and its progress to date.

Hypoxia monitoring activities within the FP7 EU-project HYPOX: diverse approaches to understand a complex phenomenon

NASA Astrophysics Data System (ADS)

Janssen, F.; Waldmann, C.; Boetius, A.

2012-04-01

Hypoxic conditions in aquatic systems and the occurrence of 'dead zones' increase worldwide due to man-made eutrophication and global warming with consequences for biodiversity, ecosystem functions and services such as fisheries, aquaculture and tourism. Monitoring of hypoxia and its consequences has to (1) account for the appropriate temporal and spatial scales, (2) separate anthropogenic from natural drivers and long-term trends from natural variations, (3) assess ecosystem response, (4) use modeling tools for generalization and prediction, and (5) share data and obtained knowledge. In 2009 the EU FP7 project HYPOX (www.hypox.net) started out as a pioneering attempt to improve and integrate hypoxia observation capacities addressing these requirements. Target ecosystems selected for HYPOX cover a broad range of settings (e.g., hydrography, oxygenation status, biological activity, anthropogenic impact) and differ in their sensitivity towards change. Semi-enclosed basins with permanent anoxia (Black Sea, Baltic Sea), are included as well as seasonally or locally hypoxic land-locked systems (fjords, lagoons, lakes) and open ocean systems with high sensitivity to global warming (North Atlantic - Arctic transition). Adopted monitoring approaches involve autonomous, cabled, and shipboard instruments and include static and profiling moorings, benthic observatories, drifters, as well as classical CTD surveys. In order to improve observatory performance, project activities encompass developments of oxygen sensors as well as calibration procedures and technologies to reduce biofouling. Modeling and data assimilation are used to synthesize findings, to obtain an in-depth understanding of hypoxia causes and consequences, and to improve forecasting capacities. For integration of the collected information into a global oxygen observing system, results are disseminated through the HYPOX portal following GEOSS data sharing principles. This presentation will give an overview of the scientific approach of HYPOX and highlight some key results comprising findings from individual ecosystems and indentified general patterns. The driving forces that lead to hypoxia are assessed as well as consequences of oxygen depletion for aquatic life and biogeochemical processes.

Job Sharing in Geography.

ERIC Educational Resources Information Center

Kay, Jeanne

1982-01-01

Job sharing is an employment alternative in which two qualified individuals manage the responsibilities of a single position. Discusses the barriers to and the potential, advantages, disadvantages, pitfalls, and challenges of job sharing. Focuses on job sharing in the geography profession. (Author/JN)

77 FR 54640 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-05

... the Listing and Trading of Shares of the WisdomTree Global Corporate Bond Fund of the WisdomTree Trust... of the WisdomTree Global Corporate Bond Fund (``Fund'') of the WisdomTree Trust (``Trust'') under...) (SR-NASDAQ-2012-004) (order approving listing and trading of WisdomTree Emerging Markets Corporate...

Lessons Learned from Implementing an Intercultural Communication Training Program for Pre-Departure Expatriates

ERIC Educational Resources Information Center

Velten, Justin C.

2015-01-01

Expatriate preparation is an ever growing area of interest in a globalized economy sharing a globalized workforce. For decades, scholars have sought methods for best preparing expatriates for host culture experiences. Research has revealed an array of factors leading to intercultural readiness success which has led to the creation of various…

Developing a global aeronautical satellite system

NASA Technical Reports Server (NTRS)

Dement, Donald K.

1988-01-01

Arinc, an airline industry-owned and operated company in the United States, has taken steps toward establishing a global aeronautical satellite communications system. Plans call for initiation of a thin-route data operation in 1989, upgrading to establish voice communications via shared spot-beam transponders carried on other satellites, and deploying a worldwide network using dedicated satellites by 1994.

Internationalisation of Higher Education and Global Mobility. Oxford Studies in Comparative Education

ERIC Educational Resources Information Center

Streitwieser, Bernhard, Ed.

2014-01-01

Continuous and rapid developments in global higher education today more than ever before present new questions, greater challenges, and vast new opportunities for institutions, policy makers, scholars and students alike. This book is a collection of studies and essays by many of the leading experts in international higher education who share their…

Trade Liberalization and Women's Integration into National Labor Markets: A Cross-Country Analysis

ERIC Educational Resources Information Center

Meyer, Lisa B.

2006-01-01

This paper examines the effects of trade liberalization and the risks associated with participation in the global trading system on women's integration into national labor markets. Using data from 1970 to 1995, I identify two global determinants of the female share of national labor markets: trade openness and transnational corporate penetration.…

Shared and Unique Genetic and Environmental Influences on Aging-Related Changes in Multiple Cognitive Abilities

ERIC Educational Resources Information Center

Tucker-Drob, Elliot M.; Reynolds, Chandra A.; Finkel, Deborah; Pedersen, Nancy L.

2014-01-01

Aging-related declines occur in many different domains of cognitive function during middle and late adulthood. However, whether a global dimension underlies individual differences in changes in different domains of cognition and whether global genetic influences on cognitive changes exist is less clear. We addressed these issues by applying…

A Global Effort for Educational Equity

ERIC Educational Resources Information Center

Dzulkifli, Dzameer

2015-01-01

A look at Teach For All's global work through the lens of Teach For Malaysia one of several dozen organizations around the world inspired by Teach For America and Teach First to share solutions as they adapt a common approach to tackle education inequality in their home countries. A deeper look at Malaysian education brought Teach For Malaysia to…

Global Injustice, Pedagogy and Democratic Iterations: Some Reflections on Why Teachers Matter

ERIC Educational Resources Information Center

Unterhalter, Elaine

2017-01-01

The article argues teachers matter because of their potential to engage in critical reflection on values associated with connecting the local, the national and the global. Their practice can support those who are dislocated, and who have no place. Teachers matter because they can help us understand how we share humanity and aspirations across many…

Literacy, Play and Globalization: Converging Imaginaries in Children's Critical and Cultural Performances. Routledge Research in Education

ERIC Educational Resources Information Center

Medina, Carmen L.; Wohlwend, Karen E.

2014-01-01

This book takes on current perspectives on children's relationships to literacy, media, childhood, markets and transtionalism in converging global worlds. It introduces the idea of multi-sited imaginaries to explain how children's media and literacy performances shape and are shaped by shared visions of communities that we collectively imagine,…

Literature and Public Discourse in Times of Global Unrest.

ERIC Educational Resources Information Center

Lindblom, Kenneth

2003-01-01

Notes English teachers already do communal, even global, work whether or not they are conscious of doing so. Examines both positive and negative consequences of that work and suggests ways of understanding it most effectively. Presents ideas on the theme of this issue, "Talking Literature." Shares a brief essay by Wail S. Hassan in which…

A prototype system for multilingual data discovery of International Long-Term Ecological Research (ILTER) Network data

Treesearch

Kristin Vanderbilt; John H. Porter; Sheng-Shan Lu; Nic Bertrand; David Blankman; Xuebing Guo; Honglin He; Don Henshaw; Karpjoo Jeong; Eun-Shik Kim; Chau-Chin Lin; Margaret O' Brien; Takeshi Osawa; Éamonn Ó Tuama; Wen Su; Haibo Yang

2017-01-01

Shared ecological data have the potential to revolutionize ecological research just as shared genetic sequence data have done for biological research. However, for ecological data to be useful, it must first be discoverable. A broad-scale research topic may require that a researcher be able to locate suitable data from a variety of global, regional and national data...

Report to Congress on the Strategic Defense Initiative, 1992

DTIC Science & Technology

1992-07-01

1.4.3 Shared View on Defenses .............................................................. 1-6 1.5 U.S. Contribution to a Global Defense System...including, in our view , that such defenses would not threaten existing deterrents--and the willingness of the U.S. to extend protection to allies...representing the central government as well as several Republics, the presentation was positively received. 1.4.3 Shared View on Defenses President

Satellites as Shared Resources for Caribbean Climate and Health Studies

NASA Technical Reports Server (NTRS)

Maynard, Nancy G.

2002-01-01

Remotely-sensed data and observations are providing powerful new tools for addressing climate and environment-related human health problems through increased capabilities for monitoring, risk mapping, and surveillance of parameters useful to such problems as vector-borne and infectious diseases, air and water quality, harmful algal blooms, UV (ultraviolet) radiation, contaminant and pathogen transport in air and water, and thermal stress. Remote sensing, geographic information systems (GIS), global positioning systems (GPS), improved computational capabilities, and interdisciplinary research between the Earth and health science communities are being combined in rich collaborative efforts resulting in more rapid problem-solving, early warning, and prevention in global health issues. Collaborative efforts among scientists from health and Earth sciences together with local decision-makers are enabling increased understanding of the relationships between changes in temperature, rainfall, wind, soil moisture, solar radiation, vegetation, and the patterns of extreme weather events and the occurrence and patterns of diseases (especially, infectious and vector-borne diseases) and other health problems. This increased understanding through improved information and data sharing, in turn, empowers local health and environmental officials to better predict health problems, take preventive measure, and improve response actions. This paper summarizes the remote sensing systems most useful for climate, environment and health studies of the Caribbean region and provides several examples of interdisciplinary research projects in the Caribbean currently using remote sensing technologies. These summaries include the use of remote sensing of algal blooms, pollution transport, coral reef monitoring, vectorborne disease studies, and potential health effects of African dust on Trinidad and Barbados.

Footprinting analysis of interactions between the largest eukaryotic RNase P/MRP protein Pop1 and RNase P/MRP RNA components

PubMed Central

Fagerlund, Robert D.; Perederina, Anna; Berezin, Igor; Krasilnikov, Andrey S.

2015-01-01

Ribonuclease (RNase) P and RNase MRP are closely related catalytic ribonucleoproteins involved in the metabolism of a wide range of RNA molecules, including tRNA, rRNA, and some mRNAs. The catalytic RNA component of eukaryotic RNase P retains the core elements of the bacterial RNase P ribozyme; however, the peripheral RNA elements responsible for the stabilization of the global architecture are largely absent in the eukaryotic enzyme. At the same time, the protein makeup of eukaryotic RNase P is considerably more complex than that of the bacterial RNase P. RNase MRP, an essential and ubiquitous eukaryotic enzyme, has a structural organization resembling that of eukaryotic RNase P, and the two enzymes share most of their protein components. Here, we present the results of the analysis of interactions between the largest protein component of yeast RNases P/MRP, Pop1, and the RNA moieties of the enzymes, discuss structural implications of the results, and suggest that Pop1 plays the role of a scaffold for the stabilization of the global architecture of eukaryotic RNase P RNA, substituting for the network of RNA–RNA tertiary interactions that maintain the global RNA structure in bacterial RNase P. PMID:26135751

Improvement in latent variable indirect response modeling of multiple categorical clinical endpoints: application to modeling of guselkumab treatment effects in psoriatic patients.

PubMed

Hu, Chuanpu; Randazzo, Bruce; Sharma, Amarnath; Zhou, Honghui

2017-10-01

Exposure-response modeling plays an important role in optimizing dose and dosing regimens during clinical drug development. The modeling of multiple endpoints is made possible in part by recent progress in latent variable indirect response (IDR) modeling for ordered categorical endpoints. This manuscript aims to investigate the level of improvement achievable by jointly modeling two such endpoints in the latent variable IDR modeling framework through the sharing of model parameters. This is illustrated with an application to the exposure-response of guselkumab, a human IgG1 monoclonal antibody in clinical development that blocks IL-23. A Phase 2b study was conducted in 238 patients with psoriasis for which disease severity was assessed using Psoriasis Area and Severity Index (PASI) and Physician's Global Assessment (PGA) scores. A latent variable Type I IDR model was developed to evaluate the therapeutic effect of guselkumab dosing on 75, 90 and 100% improvement of PASI scores from baseline and PGA scores, with placebo effect empirically modeled. The results showed that the joint model is able to describe the observed data better with fewer parameters compared with the common approach of separately modeling the endpoints.

The long-term fate of permafrost peatlands under rapid climate warming

PubMed Central

Swindles, Graeme T.; Morris, Paul J.; Mullan, Donal; Watson, Elizabeth J.; Turner, T. Edward; Roland, Thomas P.; Amesbury, Matthew J.; Kokfelt, Ulla; Schoning, Kristian; Pratte, Steve; Gallego-Sala, Angela; Charman, Dan J.; Sanderson, Nicole; Garneau, Michelle; Carrivick, Jonathan L.; Woulds, Clare; Holden, Joseph; Parry, Lauren; Galloway, Jennifer M.

2015-01-01

Permafrost peatlands contain globally important amounts of soil organic carbon, owing to cold conditions which suppress anaerobic decomposition. However, climate warming and permafrost thaw threaten the stability of this carbon store. The ultimate fate of permafrost peatlands and their carbon stores is unclear because of complex feedbacks between peat accumulation, hydrology and vegetation. Field monitoring campaigns only span the last few decades and therefore provide an incomplete picture of permafrost peatland response to recent rapid warming. Here we use a high-resolution palaeoecological approach to understand the longer-term response of peatlands in contrasting states of permafrost degradation to recent rapid warming. At all sites we identify a drying trend until the late-twentieth century; however, two sites subsequently experienced a rapid shift to wetter conditions as permafrost thawed in response to climatic warming, culminating in collapse of the peat domes. Commonalities between study sites lead us to propose a five-phase model for permafrost peatland response to climatic warming. This model suggests a shared ecohydrological trajectory towards a common end point: inundated Arctic fen. Although carbon accumulation is rapid in such sites, saturated soil conditions are likely to cause elevated methane emissions that have implications for climate-feedback mechanisms. PMID:26647837

Global surgery: current evidence for improving surgical care.

PubMed

Fuller, Jennifer C; Shaye, David A

2017-08-01

The field of global surgery is undergoing rapid transformation, owing to several recent prominent reports positioning it as a cost-effective means of relieving global disease burden. The purpose of this article is to review the recent advances in the field of global surgery. Efforts to grow the global surgical workforce and procedural capacity have focused on innovative methods to increase surgeon training, enhance international collaboration, leverage technology, optimize existing health systems, and safely implement task-sharing. Computer modeling offers a novel means of informing policy to optimize timely access to care, equitably promote health and financial protection, and efficiently grow infrastructure. Tools and checklists have recently been developed to enhance data collection and ensure methodologically rigorous publications to inform planning, benchmark surgical systems, promote accurate modeling, track key health indicators, and promote safety. Creation of institutional partnerships and trainee exchanges can enrich training, stimulate commitment to humanitarian work, and promote the equal exchange of ideas and expertise. The recent body of work creates a strong foundation upon which work toward the goal of universal access to safe, affordable surgical care can be built; however, further collection and analysis of country-specific data is necessary for accurate modeling and outcomes research into the efficacy of policies such as task-sharing is greatly needed.

Job-sharing a clinical teacher's position: an evaluation.

PubMed

Williams, S; Murphy, L

1994-01-01

The aim of this study was to evaluate the effects on staff of having two teachers share one clinical teaching position in their intensive care unit (ICU). Three, six and 12 months after the job-sharing arrangement was initiated, an 11 item questionnaire was distributed to 26 students in post-registration critical care courses, 41 clinical staff in ICU and 9 RN-managers with responsibilities for the unit. The overall response rate to the three questionnaires was 58%. All groups agreed that job-sharing was a viable alternative to full-time work. Three months after the shared position was initiated, there was uncertainty about the consistency of the teachers' performance and the adequacy of communication between them. Nine months later, there was a high level of positive responses to all areas of the teachers' performance. Most respondents felt they could approach either teacher and that more diverse ideas were generated by having two people in the teaching position.

Life in unexpected places: Employing visual thinking strategies in global health training.

PubMed

Allison, Jill; Mulay, Shree; Kidd, Monica

2017-01-01

The desire to make meaning out of images, metaphor, and other representations indicates higher-order cognitive skills that can be difficult to teach, especially in the complex and unfamiliar environments like those encountered in many global health experiences. Because reflecting on art can help develop medical students' imaginative and interpretive skills, we used visual thinking strategies (VTS) during an immersive 4-week global health elective for medical students to help them construct new understanding of the social determinants of health in a low-resource setting. We were aware of no previous formal efforts to use art in global health training. We assembled a group of eight medical students in front of a street mural in Kathmandu and used VTS methods to interpret the scene with respect to the social determinants of health. We recorded and transcribed the conversation and conducted a thematic analysis of student responses. Students shared observations about the mural in a supportive, nonjudgmental fashion. Two main themes emerged from their observations: those of human-environment interactions (specifically community dynamics, subsistence land use, resources, and health) and entrapment/control, particularly relating to expectations of, and demands on, women in traditional farming communities. They used the images as well as their experience in Nepali communities to consolidate complex community health concepts. VTS helped students articulate their deepening understanding of the social determinants of health in Nepal, suggesting that reflection on visual art can help learners apply, analyze, and evaluate complex concepts in global health. We demonstrate the relevance of drawing upon many aspects of cultural learning, regarding art as a kind of text that holds valuable information. These findings may help provide innovative opportunities for teaching and evaluating global health training in the future.

Working with Planetary-Scale Data in the Cloud

NASA Astrophysics Data System (ADS)

Flasher, J.

2017-12-01

When data is shared on AWS, it can be analyzed using AWS on-demand computing resources quickly and efficiently. Users can work with any amount of data without needing to download it or store their own copies. When heavy data like imagery, genomics data, or volumes of sensor data are available in AWS's cloud, the time required to copy the data to a virtual server for analysis is virtually eliminated. AWS's global infrastructure allows data providers to make their data available worldwide and ensure quick access to critical data from anywhere. In this session, we will share lessons learned from our experience supporting a global community of entrepreneurs, students and researchers by making petabytes of data freely available for anyone to use in the cloud.

From Corporate Social Responsibility, through Entrepreneurial Orientation, to Knowledge Sharing: A Study in Cai Luong (Renovated Theatre) Theatre Companies

ERIC Educational Resources Information Center

Tuan, Luu Trong

2015-01-01

Purpose: This paper aims to examine the role of antecedents such as corporate social responsibility (CSR) and entrepreneurial orientation in the chain effect to knowledge sharing among members of Cai Luong theatre companies in the Vietnamese context. Knowledge sharing contributes to the depth of the knowledge pool of both the individuals and the…

Fungal symbionts alter plant responses to global change.

PubMed

Kivlin, Stephanie N; Emery, Sarah M; Rudgers, Jennifer A

2013-07-01

While direct plant responses to global change have been well characterized, indirect plant responses to global change, via altered species interactions, have received less attention. Here, we examined how plants associated with four classes of fungal symbionts (class I leaf endophytes [EF], arbuscular mycorrhizal fungi [AMF], ectomycorrhizal fungi [ECM], and dark septate endophytes [DSE]) responded to four global change factors (enriched CO2, drought, N deposition, and warming). We performed a meta-analysis of 434 studies spanning 174 publications to search for generalizable trends in responses of plant-fungal symbioses to future environments. Specifically, we addressed the following questions: (1) Can fungal symbionts ameliorate responses of plants to global change? (2) Do fungal symbiont groups differ in the degree to which they modify plant response to global change? (3) Do particular global change factors affect plant-fungal symbioses more than others? In all global change scenarios, except elevated CO2, fungal symbionts significantly altered plant responses to global change. In most cases, fungal symbionts increased plant biomass in response to global change. However, increased N deposition reduced the benefits of symbiosis. Of the global change factors we considered, drought and N deposition resulted in the strongest fungal mediation of plant responses. Our analysis highlighted gaps in current knowledge for responses of particular fungal groups and revealed the importance of considering not only the nonadditive effects of multiple global change factors, but also the interactive effects of multiple fungal symbioses. Our results show that considering plant-fungal symbioses is critical to predicting ecosystem response to global change.

40 CFR 35.6285 - Recipient payment of response costs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... payment of response costs. The recipient may pay for its share of response costs using cash, services... costs in the form of cash. (b) Services. The recipient may provide equipment and services to satisfy its... CFR part 300). (d) Excess cash cost share contributions/overmatch. The recipient may direct EPA to...

InsightSTEM Campus Ambassadors: Worldwide Grassroots Student Networking, Development, and Outreach

NASA Astrophysics Data System (ADS)

Nuccitelli, D. A.

2016-12-01

We present results on our Campus Ambassadors program, which in three years has grown, through grassroots networking, to comprise over 550 members in over 30 countries worldwide. We will share our experiences of peer-to-peer network growth on an international scale, as well as issues with growth and program impacts in the USA, South America, Africa, Asia and Europe. InsightSTEM seeks to democratize STEM knowledge through exploration, and our Campus Ambassadors are supported in their desire to share their own STEM knowledge with their broader communities. They have impacts by supporting individuals becoming critically thinking, STEM literate, global learners. Since its inception in 2014, the program has relied on its members to continue to expand the program. The most notable impacts globally have been with students in India, and in West Africa (most notably Liberia). We will discuss the challenges and outcomes of providing a global program for these vastly diverse communities, and strategies we are testing to ensure an equitable experience for all participants.

InsightSTEM Campus Ambassadors: Worldwide Grassroots Student Networking, Development, and Outreach

NASA Astrophysics Data System (ADS)

Noel-Storr, J.

2017-12-01

We present results on our Campus Ambassadors program, which in three years has grown, through grassroots networking, to comprise over 550 members in over 30 countries worldwide. We will share our experiences of peer-to-peer network growth on an international scale, as well as issues with growth and program impacts in the USA, South America, Africa, Asia and Europe. InsightSTEM seeks to democratize STEM knowledge through exploration, and our Campus Ambassadors are supported in their desire to share their own STEM knowledge with their broader communities. They have impacts by supporting individuals becoming critically thinking, STEM literate, global learners. Since its inception in 2014, the program has relied on its members to continue to expand the program. The most notable impacts globally have been with students in India, and in West Africa (most notably Liberia). We will discuss the challenges and outcomes of providing a global program for these vastly diverse communities, and strategies we are testing to ensure an equitable experience for all participants.

Healthcare provider education: from institutional boxes to dynamic networks.

PubMed

Eisler, George

2009-01-01

The world recognizes the need for close collaboration in planning between the healthcare system and the post-secondary education system; this has also been advocated in the lead article. Forums and mechanisms to facilitate this collaboration are being implemented from local to global environments. Beyond the focus on competency gaps, there are important functional co-dependencies between healthcare and post-secondary education, including the need for a more formalized continuous quality improvement approach at the inter-organizational system level. The case for this close and continuous collaborative relationship is based on the following: (1) a close functional relationship, (2) joint responsibility for healthcare provider education, (3) the urgent need to address the workforce and education strategies for almost all healthcare services areas and (4) the factors that characterize successful and sustained quality improvement in complex adaptive systems. A go-forward vision consisting of an integrated web of academic health networks is proposed, each with its particular shared vision and aligned with an overall vision for healthcare in each provincial jurisdiction, as well as with national and global healthcare objectives.

Institute of social justice and medicine: developing a think tank to promote policy formation.

PubMed

Boozary, Andrew; Dugani, Sagar B

2011-10-01

The World Health Organization (WHO) defines health as a "resource for everyday living, not the objective of living"; however, worldwide, there remains an unmistakable inequity in level of health and access to healthcare. The WHO has published documents on financing health systems towards universal health coverage [1], promoting healthy life [2], improving performance of health systems [3], and enriching humanity [4], highlighting our shared responsibility towards improving both national and global health and access to healthcare. These documents also recognize that, despite our local and regional priorities, there is a global desire to develop international strategies to improve healthcare. [1] WHO Report. Health systems financing and the path to universal coverage. 2010. http://www.who.int/bulletin/health_financing/en/index.html [2] WHO Report. Reducing risks, promoting healthy life. 2002. http://www.who.int/whr/2002/en/index.html [3] WHO Bulletin. Health systems: improving performance. 2000. http://www.who.int/whr/2000/en/index.html [4] WHO Bulletin. Conquering suffering, enriching humanity 1997. http://www.who.int/whr/1997/en/index.html.

The Mycotox Charter: Increasing Awareness of, and Concerted Action for, Minimizing Mycotoxin Exposure Worldwide

PubMed Central

Logrieco, Antonio F.; Eskola, Mari; Krska, Rudolf; Ayalew, Amare; Bhatnagar, Deepak; Chulze, Sofia; Li, Peiwu; Poapolathep, Amnart; Rahayu, Endang S.; Shephard, Gordon S.; Stepman, François; Zhang, Hao

2018-01-01

Mycotoxins are major food contaminants affecting global food security, especially in low and middle-income countries. The European Union (EU) funded project, MycoKey, focuses on “Integrated and innovative key actions for mycotoxin management in the food and feed chains” and the right to safe food through mycotoxin management strategies and regulation, which are fundamental to minimizing the unequal access to safe and sufficient food worldwide. As part of the MycoKey project, a Mycotoxin Charter (charter.mycokey.eu) was launched to share the need for global harmonization of mycotoxin legislation and policies and to minimize human and animal exposure worldwide, with particular attention to less developed countries that lack effective legislation. This document is in response to a demand that has built through previous European Framework Projects—MycoGlobe and MycoRed—in the previous decade to control and reduce mycotoxin contamination worldwide. All suppliers, participants and beneficiaries of the food supply chain, for example, farmers, consumers, stakeholders, researchers, members of civil society and government and so forth, are invited to sign this charter and to support this initiative. PMID:29617309

The Mycotox Charter: Increasing Awareness of, and Concerted Action for, Minimizing Mycotoxin Exposure Worldwide.

PubMed

Logrieco, Antonio F; Miller, J David; Eskola, Mari; Krska, Rudolf; Ayalew, Amare; Bandyopadhyay, Ranajit; Battilani, Paola; Bhatnagar, Deepak; Chulze, Sofia; De Saeger, Sarah; Li, Peiwu; Perrone, Giancarlo; Poapolathep, Amnart; Rahayu, Endang S; Shephard, Gordon S; Stepman, François; Zhang, Hao; Leslie, John F

2018-04-04

Mycotoxins are major food contaminants affecting global food security, especially in low and middle-income countries. The European Union (EU) funded project, MycoKey, focuses on “Integrated and innovative key actions for mycotoxin management in the food and feed chains” and the right to safe food through mycotoxin management strategies and regulation, which are fundamental to minimizing the unequal access to safe and sufficient food worldwide. As part of the MycoKey project, a Mycotoxin Charter (charter.mycokey.eu) was launched to share the need for global harmonization of mycotoxin legislation and policies and to minimize human and animal exposure worldwide, with particular attention to less developed countries that lack effective legislation. This document is in response to a demand that has built through previous European Framework Projects—MycoGlobe and MycoRed—in the previous decade to control and reduce mycotoxin contamination worldwide. All suppliers, participants and beneficiaries of the food supply chain, for example, farmers, consumers, stakeholders, researchers, members of civil society and government and so forth, are invited to sign this charter and to support this initiative.

DataONE: Survey of Earth Scientists, To Share or Not to Share Data

NASA Astrophysics Data System (ADS)

Branch, B. D.; Tenopir, C.; Allard, S.; Douglas, K.; Wu, L.; Frame, M.; Dataone-The Data Observation NetworkEarth

2010-12-01

A primary goal of the Data Observation Network for Earth (DataONE; http://dataone.org) is to ensure preservation and access to multi-scale, multi-discipline, and multi-national science data, particularly in the Earth and Environmental Sciences. As a means to measure project success and to better understand the needs of the community, we have conducted a baseline assessment of the data sharing practices and preferences of domain scientists. The survey is motivated by the understanding that improving access to the sharing of data requires changes in both technology and expectations of the scientific community. A follow-up survey conducted in the future will measure how data sharing initiatives such as DataONE have influenced attitudes and behaviors. A letter of invitation with a link to an online survey instrument was emailed to scientists. Scientists were contacted by several methods: through contacts at the universities where they work, through journal editors of science journals, and directly to biology and environmental science faculty at major U.S. universities. A total of 1329 responses were received. The overall findings from the baseline assessment demonstrate several key findings. -Data management practices vary: {56.1%of respondents did not use any metadata standard, 22.1% used a lab created metadata standard, and over half of respondents 59% (local site) and 55% (national site) mentioned that at least some of their data were available; only 42% (global) and 35% (regional site) respondents mentioned that their data were available.} -Many scientists are interested in sharing data. Over 80% of respondents agreed with the statements: {“I would use other researchers' datasets if their datasets were easily accessible.” and “I would be willing to share data across a broad group of researchers who use data in different ways.”} -There are many barriers to sharing data. The two most common barriers identified were: {Insufficient time (54%) and Lack of funding (40%)} -Some disciplines are using good data management practices: {90% of atmospheric scientists say they share data with others, and 49% of atmospheric scientists agree with the statement “Others can access my data easily”} Results will be compared with other recent surveys of data management practices, including Dryad digital repository efforts (NSF EF-0423641) and Permanent Access to the Records of Science in Europe (2010) study. Future work will seek to further investigate such findings by conducting in-depth profiles and possible personas development as an evidenced based rationale for earth scientists’ data sharing practices.

[International financial cooperation in the fight against AIDS in Latin America and the Caribbean].

PubMed

Leyva-Flores, René; Castillo, José Gabriel; Serván-Mori, Edson; Ballesteros, Maria Luisa Gontes; Rodríguez, Juan Francisco Molina

2014-07-01

This study analyzed the financial contribution by the Global Fund to Fight HIV/AIDS, Tuberculosis, and Malaria and its relationship to eligibility criteria for funding in Latin America and the Caribbean in 2002-2010. Descriptive analysis (linear regression) was conducted for the Global Fund financial contributions according to eligibility criteria (income level, burden of disease, governmental co-investment). Financial contributions totaled US$ 705 million. Lower-income countries received higher shares; there was no relationship between Global Fund contributions and burden of disease. The Global Fund's international financing complements governmental expenditure, with equity policies for financial allocation.

Global payment for health services as a solution in the financial crisis in Europe.

PubMed

Schrijvers, Guus

2012-10-01

In these financial difficult years many European governments used global ceilings to control costs of health services. Two scenarios are thinkable. The first is that all individual providers get a budget for their own costs: general practitioners, specialists, hospitals, nursing homes and mental health institutes. The second scenario is to work with global budgets for health care providers servicing a total population. Scientists and policy makers in Europe, North America and Asia need time to design new payment systems based on the idea of global budgeting, bundled payment and shared savings.

Shared decision-making at the end of life: A focus group study exploring the perceptions and experiences of multi-disciplinary healthcare professionals working in the home setting.

PubMed

Brogan, Paula; Hasson, Felicity; McIlfatrick, Sonja

2018-01-01

Globally recommended in healthcare policy, Shared Decision-Making is also central to international policy promoting community palliative care. Yet realities of implementation by multi-disciplinary healthcare professionals who provide end-of-life care in the home are unclear. To explore multi-disciplinary healthcare professionals' perceptions and experiences of Shared Decision-Making at end of life in the home. Qualitative design using focus groups, transcribed verbatim and analysed thematically. A total of 43 participants, from multi-disciplinary community-based services in one region of the United Kingdom, were recruited. While the rhetoric of Shared Decision-Making was recognised, its implementation was impacted by several interconnecting factors, including (1) conceptual confusion regarding Shared Decision-Making, (2) uncertainty in the process and (3) organisational factors which impeded Shared Decision-Making. Multiple interacting factors influence implementation of Shared Decision-Making by professionals working in complex community settings at the end of life. Moving from rhetoric to reality requires future work exploring the realities of Shared Decision-Making practice at individual, process and systems levels.

Sharing data is a shared responsibility: Commentary on: "The essential nature of sharing in science".

PubMed

Giffels, Joe

2010-12-01

Research data should be made readily available. A robust data-sharing plan, led by the principal investigator of the research project, requires considerable administrative and operational resources. Because external support for data sharing is minimal, principal investigators should consider engaging existing institutional information experts, such as librarians and information systems personnel, to participate in data-sharing efforts.

Planning for Reform of the Governance of the Military Health System

DTIC Science & Technology

2012-03-02

functions that are determined to be assigned to the ASD(HA). In addition, the DHA will assume responsibility for shared services , functions, and...operational capability for the DHA, the shared services and other functions and activities for which the DHA will have responsibility, the potential use of...and business processes and the consolidation and standardization of various shared services . They are also informed by a recognition that there

A neighborhood susceptibility index for planning of local physical interventions in response to pandemic influenza outbreaks

PubMed Central

Timpka, Toomas; Eriksson, Henrik; Strömgren, Magnus; Eriksson, Olle; Ekberg, Joakim; Grimvall, Anders; Nyce, James; Gursky, Elin; Holm, Einar

2010-01-01

The global spread of a novel A (H1N1) influenza virus in 2009 has highlighted the possibility of a devastating pandemic similar to the ‘Spanish flu’ of 1917–1918. Responding to such pandemics requires careful planning for the early phases where there is no availability of pandemic vaccine. We set out to compute a Neighborhood Influenza Susceptibility Index (NISI) describing the vulnerability of local communities of different geo-socio-physical structure to a pandemic influenza outbreak. We used a spatially explicit geo-physical model of Linköping municipality (pop. 136,240) in Sweden, and employed an ontology-modeling tool to define simulation models and transmission settings. We found considerable differences in NISI between neighborhoods corresponding to primary care areas with regard to early progress of the outbreak, as well as in terms of the total accumulated share of infected residents counted after the outbreak. The NISI can be used in local preparations of physical response measures during pandemics. PMID:21347087

Web Ontologies to Categorialy Structure Reality: Representations of Human Emotional, Cognitive, and Motivational Processes

PubMed Central

López-Gil, Juan-Miguel; Gil, Rosa; García, Roberto

2016-01-01

This work presents a Web ontology for modeling and representation of the emotional, cognitive and motivational state of online learners, interacting with university systems for distance or blended education. The ontology is understood as a way to provide the required mechanisms to model reality and associate it to emotional responses, but without committing to a particular way of organizing these emotional responses. Knowledge representation for the contributed ontology is performed by using Web Ontology Language (OWL), a semantic web language designed to represent rich and complex knowledge about things, groups of things, and relations between things. OWL is a computational logic-based language such that computer programs can exploit knowledge expressed in OWL and also facilitates sharing and reusing knowledge using the global infrastructure of the Web. The proposed ontology has been tested in the field of Massive Open Online Courses (MOOCs) to check if it is capable of representing emotions and motivation of the students in this context of use. PMID:27199796

Rule-Selection and Action-Selection have a Shared Neuroanatomical Basis in the Human Prefrontal and Parietal Cortex

PubMed Central

Hughes, L.; Eckstein, D.; Owen, A.M.

2008-01-01

The human capacity for voluntary action is one of the major contributors to our success as a species. In addition to choosing actions themselves, we can also voluntarily choose behavioral codes or sets of rules that can guide future responses to events. Such rules have been proposed to be superordinate to actions in a cognitive hierarchy and mediated by distinct brain regions. We used event-related functional magnetic resonance imaging to study novel tasks of rule-based and voluntary action. We show that the voluntary selection of rules to govern future responses to events is associated with activation of similar regions of prefrontal and parietal cortex as the voluntary selection of an action itself. The results are discussed in terms of hierarchical models and the adaptive coding potential of prefrontal neurons and their contribution to a global workspace for nonautomatic tasks. These tasks include the choices we make about our behavior. PMID:18234684

Notes from a field hospital south of Mosul.

PubMed

Quinn V, John M; Amouri, Omar F; Reed, Pete

2018-03-06

This short letter from the field is offered as a rapid communiqué of the emergency medical situation in Mosul and surrounding areas on the eve of the final onslaught to liberate the city. This letter is based on emergency medical work at two World Health Organization (WHO) and Ministry of Health (MoH) Iraq lead Role II+ Field Hospital facilities south of Mosul City from April to June 2017; these facilities are currently and temporarily managed and administered by private medical industry until full handover to MoH Iraq, with WHO support and expert facilitation. The prominence of non-state actors in the conflict, using hybrid warfare tactics that maximize casualties, makes health security a particular challenge for the global community. This challenge requires health leaders and other actors in the region to set clear strategic goals that support public health of the many millions displaced, maimed and affected by the war. Whether in clinical medicine, development, peace and stability operations, or global health diplomacy, the shared values and conviction to best serve vulnerable communities and mitigate morbidity must embrace the lessons of evidenced based practice derived from military medical experience. WHO is leading the charge in disaster response for the conflict in Iraq, and many challenges remain. This might also include developing a new process in emergency medical response that utilizes private contracting to improve efficiency in delivery and overall sustainability.

You Tube: An International Medium for Sharing Videos about Hookah Smoking

ERIC Educational Resources Information Center

Seitz, Christopher M.; Milroy, Jeffrey J.; Orsini, Muhsin Michael; Wyrick, David L.; Herring, Jeremy; Koech, Mike

2011-01-01

The hookah pipe is an ancient tool for smoking tobacco and is a growing public health concern at the global level. YouTube is a website that allows its members to post videos for people to watch and to share comments about the videos in an online forum. The purpose of the study was to investigate the types of videos about hookah on YouTube, their…

Progress Toward a Global Perspective of Environmental Quality: Strategies to Affect Student Awareness of the Environment.

ERIC Educational Resources Information Center

Peters, Richard O.

National and International Conferences on Environmental Education have been held over the last three years. These provide a global perspective that is translated into goals and objectives for environmental education programs in the United States. Emphasis is on the need to educate people to the fact that all mankind shares the earth and that with…

Reflections on Global Developments in Media Literacy Education: Bridging Theory and Practice

ERIC Educational Resources Information Center

Hobbs, Renee; Felini, Damiano; Cappello, Gianna

2011-01-01

The field of media literacy education is maturing, as evidenced by the quality of presentations of research and practice shared at the 2010 World Summit on Children and Media in Karlstad. In this article, we offer our reflections on the opportunities and challenges faced by media literacy educators as we build our global community network, develop…

School Nurses Share a Job.

ERIC Educational Resources Information Center

Merwin, Elizabeth G.; Voss, Sondra

1981-01-01

Job sharing is a relatively new idea in which two or more people share the hours, the work, and the responsibilities of one job. Advantages and disadvantages to this situation are discussed in relation to the experiences of two nurses who shared a position as district nurse. (JN)

Precision global health in the digital age.

PubMed

Flahault, Antoine; Geissbuhler, Antoine; Guessous, Idris; Guérin, Philippe; Bolon, Isabelle; Salathé, Marcel; Escher, Gérard

2017-04-19

Precision global health is an approach similar to precision medicine, which facilitates, through innovation and technology, better targeting of public health interventions on a global scale, for the purpose of maximising their effectiveness and relevance. Illustrative examples include: the use of remote sensing data to fight vector-borne diseases; large databases of genomic sequences of foodborne pathogens helping to identify origins of outbreaks; social networks and internet search engines for tracking communicable diseases; cell phone data in humanitarian actions; drones to deliver healthcare services in remote and secluded areas. Open science and data sharing platforms are proposed for fostering international research programmes under fair, ethical and respectful conditions. Innovative education, such as massive open online courses or serious games, can promote wider access to training in public health and improving health literacy. The world is moving towards learning healthcare systems. Professionals are equipped with data collection and decision support devices. They share information, which are complemented by external sources, and analysed in real time using machine learning techniques. They allow for the early detection of anomalies, and eventually guide appropriate public health interventions. This article shows how information-driven approaches, enabled by digital technologies, can help improving global health with greater equity.

A Unique Fungal Two-Component System Regulates Stress Responses, Drug Sensitivity, Sexual Development, and Virulence of Cryptococcus neoformans

PubMed Central

Bahn, Yong-Sun; Kojima, Kaihei; Cox, Gary M.

2006-01-01

The stress-activated mitogen-activated protein kinase (MAPK) pathway is widely used by eukaryotic organisms as a central conduit via which cellular responses to the environment effect growth and differentiation. The basidiomycetous human fungal pathogen Cryptococcus neoformans uniquely uses the stress-activated Pbs2-Hog1 MAPK system to govern a plethora of cellular events, including stress responses, drug sensitivity, sexual reproduction, and virulence. Here, we characterized a fungal “two-component” system that controls these fundamental cellular functions via the Pbs2-Hog1 MAPK cascade. A typical response regulator, Ssk1, modulated all Hog1-dependent phenotypes by controlling Hog1 phosphorylation, indicating that Ssk1 is the major upstream signaling component of the Pbs2-Hog1 pathway. A second response regulator, Skn7, governs sensitivity to Na+ ions and the antifungal agent fludioxonil, negatively controls melanin production, and functions independently of Hog1 regulation. To control these response regulators, C. neoformans uses multiple sensor kinases, including two-component–like (Tco) 1 and Tco2. Tco1 and Tco2 play shared and distinct roles in stress responses and drug sensitivity through the Hog1 MAPK system. Furthermore, each sensor kinase mediates unique cellular functions for virulence and morphological differentiation. Our findings highlight unique adaptations of this global two-component MAPK signaling cascade in a ubiquitous human fungal pathogen. PMID:16672377

Global Implementation of Genomic Medicine: We Are Not Alone

PubMed Central

Manolio, Teri A.; Abramowicz, Marc; Al-Mulla, Fahd; Anderson, Warwick; Balling, Rudi; Berger, Adam C.; Bleyl, Steven; Chakravarti, Aravinda; Chantratita, Wasun; Chisholm, Rex L.; Dissanayake, Vajira H. W.; Dunn, Michael; Dzau, Victor J.; Han, Bok-Ghee; Hubbard, Tim; Kolbe, Anne; Korf, Bruce; Kubo, Michiaki; Lasko, Paul; Leego, Erkki; Mahasirimongkol, Surakameth; Majumdar, Partha P.; Matthijs, Gert; McLeod, Howard L.; Metspalu, Andres; Meulien, Pierre; Miyano, Satoru; Naparstek, Yaakov; O’Rourke, P. Pearl; Patrinos, George P.; Rehm, Heidi L.; Relling, Mary V.; Rennert, Gad; Rodriguez, Laura Lyman; Roden, Dan M.; Shuldiner, Alan R.; Sinha, Sukdev; Tan, Patrick; Ulfendahl, Mats; Ward, Robyn; Williams, Marc S.; Wong, John E.L.; Green, Eric D.; Ginsburg, Geoffrey S.

2016-01-01

Advances in high-throughput genomic technologies coupled with a growing number of genomic results potentially useful in clinical care have led to ground-breaking genomic medicine implementation programs in various nations. Many of these innovative programs capitalize on unique local capabilities arising from the structure of their health care systems or their cultural or political milieu, as well as from unusual burdens of disease or risk alleles. Many such programs are being conducted in relative isolation and might benefit from sharing of approaches and lessons learned in other nations. The National Human Genome Research Institute recently brought together 25 of these groups from around the world to describe and compare projects, examine the current state of implementation and desired near-term capabilities, and identify opportunities for collaboration to promote the responsible implementation of genomic medicine. The wide variety of nascent programs in diverse settings demonstrates that implementation of genomic medicine is expanding globally in varied and highly innovative ways. Opportunities for collaboration abound in the areas of evidence generation, health information technology, education, workforce development, pharmacogenomics, and policy and regulatory issues. Several international organizations that are already facilitating effective research collaborations should engage to ensure implementation proceeds collaboratively without potentially wasteful duplication. Efforts to coalesce these groups around concrete but compelling signature projects, such as global eradication of genetically-mediated drug reactions or developing a truly global genomic variant data resource across a wide number of ethnicities, would accelerate appropriate implementation of genomics to improve clinical care world-wide. PMID:26041702

Pneumonia’s second wind? A case study of the global health network for childhood pneumonia

PubMed Central

Berlan, David

2016-01-01

Advocacy, policy, research and intervention efforts against childhood pneumonia have lagged behind other health issues, including malaria, measles and tuberculosis. Accelerating progress on the issue began in 2008, following decades of efforts by individuals and organizations to address the leading cause of childhood mortality and establish a global health network. This article traces the history of this network’s formation and evolution to identify lessons for other global health issues. Through document review and interviews with current, former and potential network members, this case study identifies five distinct eras of activity against childhood pneumonia: a period of isolation (post WWII to 1984), the duration of WHO’s Acute Respiratory Infections (ARI) Programme (1984–1995), Integrated Management of Childhood illness’s (IMCI) early years (1995–2003), a brief period of network re-emergence (2003–2008) and recent accelerating progress (2008 on). Analysis of these eras reveals the critical importance of building a shared identity in order to form an effective network and take advantage of emerging opportunities. During the ARI era, an initial network formed around a relatively narrow shared identity focused on community-level care. The shift to IMCI led to the partial dissolution of this network, stalled progress on addressing pneumonia in communities and missed opportunities. Frustrated with lack of progress on the issue, actors began forming a network and shared identity that included a broad spectrum of those whose interests overlap with pneumonia. As the network coalesced and expanded, its members coordinated and collaborated on conducting and sharing research on severity and tractability, crafting comprehensive strategies and conducting advocacy. These network activities exerted indirect influence leading to increased attention, funding, policies and some implementation. PMID:26438780

Pneumonia's second wind? A case study of the global health network for childhood pneumonia.

PubMed

Berlan, David

2016-04-01

Advocacy, policy, research and intervention efforts against childhood pneumonia have lagged behind other health issues, including malaria, measles and tuberculosis. Accelerating progress on the issue began in 2008, following decades of efforts by individuals and organizations to address the leading cause of childhood mortality and establish a global health network. This article traces the history of this network's formation and evolution to identify lessons for other global health issues. Through document review and interviews with current, former and potential network members, this case study identifies five distinct eras of activity against childhood pneumonia: a period of isolation (post WWII to 1984), the duration of WHO's Acute Respiratory Infections (ARI) Programme (1984-1995), Integrated Management of Childhood illness's (IMCI) early years (1995-2003), a brief period of network re-emergence (2003-2008) and recent accelerating progress (2008 on). Analysis of these eras reveals the critical importance of building a shared identity in order to form an effective network and take advantage of emerging opportunities. During the ARI era, an initial network formed around a relatively narrow shared identity focused on community-level care. The shift to IMCI led to the partial dissolution of this network, stalled progress on addressing pneumonia in communities and missed opportunities. Frustrated with lack of progress on the issue, actors began forming a network and shared identity that included a broad spectrum of those whose interests overlap with pneumonia. As the network coalesced and expanded, its members coordinated and collaborated on conducting and sharing research on severity and tractability, crafting comprehensive strategies and conducting advocacy. These network activities exerted indirect influence leading to increased attention, funding, policies and some implementation. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2015; all rights reserved.

Reproducing Epidemiologic Research and Ensuring Transparency.

PubMed

Coughlin, Steven S

2017-08-15

Measures for ensuring that epidemiologic studies are reproducible include making data sets and software available to other researchers so they can verify published findings, conduct alternative analyses of the data, and check for statistical errors or programming errors. Recent developments related to the reproducibility and transparency of epidemiologic studies include the creation of a global platform for sharing data from clinical trials and the anticipated future extension of the global platform to non-clinical trial data. Government agencies and departments such as the US Department of Veterans Affairs Cooperative Studies Program have also enhanced their data repositories and data sharing resources. The Institute of Medicine and the International Committee of Medical Journal Editors released guidance on sharing clinical trial data. The US National Institutes of Health has updated their data-sharing policies. In this issue of the Journal, Shepherd et al. (Am J Epidemiol. 2017;186:387-392) outline a pragmatic approach for reproducible research with sensitive data for studies for which data cannot be shared because of legal or ethical restrictions. Their proposed quasi-reproducible approach facilitates the dissemination of statistical methods and codes to independent researchers. Both reproducibility and quasi-reproducibility can increase transparency for critical evaluation, further dissemination of study methods, and expedite the exchange of ideas among researchers. © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Global Food Demand Scenarios for the 21st Century

PubMed Central

Biewald, Anne; Weindl, Isabelle; Popp, Alexander; Lotze-Campen, Hermann

2015-01-01

Long-term food demand scenarios are an important tool for studying global food security and for analysing the environmental impacts of agriculture. We provide a simple and transparent method to create scenarios for future plant-based and animal-based calorie demand, using time-dependent regression models between calorie demand and income. The scenarios can be customized to a specific storyline by using different input data for gross domestic product (GDP) and population projections and by assuming different functional forms of the regressions. Our results confirm that total calorie demand increases with income, but we also found a non-income related positive time-trend. The share of animal-based calories is estimated to rise strongly with income for low-income groups. For high income groups, two ambiguous relations between income and the share of animal-based products are consistent with historical data: First, a positive relation with a strong negative time-trend and second a negative relation with a slight negative time-trend. The fits of our regressions are highly significant and our results compare well to other food demand estimates. The method is exemplarily used to construct four food demand scenarios until the year 2100 based on the storylines of the IPCC Special Report on Emissions Scenarios (SRES). We find in all scenarios a strong increase of global food demand until 2050 with an increasing share of animal-based products, especially in developing countries. PMID:26536124

Global Food Demand Scenarios for the 21st Century.

PubMed

Bodirsky, Benjamin Leon; Rolinski, Susanne; Biewald, Anne; Weindl, Isabelle; Popp, Alexander; Lotze-Campen, Hermann

2015-01-01

Long-term food demand scenarios are an important tool for studying global food security and for analysing the environmental impacts of agriculture. We provide a simple and transparent method to create scenarios for future plant-based and animal-based calorie demand, using time-dependent regression models between calorie demand and income. The scenarios can be customized to a specific storyline by using different input data for gross domestic product (GDP) and population projections and by assuming different functional forms of the regressions. Our results confirm that total calorie demand increases with income, but we also found a non-income related positive time-trend. The share of animal-based calories is estimated to rise strongly with income for low-income groups. For high income groups, two ambiguous relations between income and the share of animal-based products are consistent with historical data: First, a positive relation with a strong negative time-trend and second a negative relation with a slight negative time-trend. The fits of our regressions are highly significant and our results compare well to other food demand estimates. The method is exemplarily used to construct four food demand scenarios until the year 2100 based on the storylines of the IPCC Special Report on Emissions Scenarios (SRES). We find in all scenarios a strong increase of global food demand until 2050 with an increasing share of animal-based products, especially in developing countries.

Polycentrism in Global Health Governance Scholarship

PubMed Central

Tosun, Jale

2018-01-01

Drawing on an in-depth analysis of eight global health networks, a recent essay in this journal argued that global health networks face four challenges to their effectiveness: problem definition, positioning, coalition-building, and governance. While sharing the argument of the essay concerned, in this commentary, we argue that these analytical concepts can be used to explicate a concept that has implicitly been used in global health governance scholarship for quite a few years. While already prominent in the discussion of climate change governance, for instance, global health governance scholarship could make progress by looking at global health governance as being polycentric. Concisely, polycentric forms of governance mix scales, mechanisms, and actors. Drawing on the essay, we propose a polycentric approach to the study of global health governance that incorporates coalitionbuilding tactics, internal governance and global political priority as explanatory factors. PMID:29325406

Exploring Resource Sharing between Secondary School Teachers of Agriculture and Science Departments Nationally.

ERIC Educational Resources Information Center

Dormody, Thomas J.

1992-01-01

A survey of 372 secondary agriculture teachers received 274 responses showing a majority of agriculture and science departments share resources, although at low levels. Many more predicted future sharing. Equipment and supplies were most often shared, instructional services least often. (SK)

42 CFR 457.560 - Cumulative cost-sharing maximum.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Cumulative cost-sharing maximum. 457.560 Section... State Plan Requirements: Enrollee Financial Responsibilities § 457.560 Cumulative cost-sharing maximum... writing and orally if appropriate of their individual cumulative cost-sharing maximum amount at the time...

Actionable knowledge and strategic decision making for bio- and agroterrorism threats: building a collaborative early warning culture.

PubMed

Mårtensson, Per-Åke; Hedström, Lars; Sundelius, Bengt; Skiby, Jeffrey E; Elbers, Armin; Knutsson, Rickard

2013-09-01

Current trends in biosecurity and cybersecurity include (1) the wide availability of technology and specialized knowledge that previously were available only to governments; (2) the global economic recession, which may increase the spread of radical non-state actors; and (3) recent US and EU commission reports that reflect concerns about non-state actors in asymmetric threats. The intersectoral and international nature of bioterrorism and agroterrorism threats requires collaboration across several sectors including intelligence, police, forensics, customs, and other law enforcement organizations who must work together with public and animal health organizations as well as environmental and social science organizations. This requires coordinated decision making among these organizations, based on actionable knowledge and information sharing. The risk of not sharing information among organizations compared to the benefit of sharing information can be considered in an "information sharing risk-benefit analysis" to prevent a terrorism incident from occurring and to build a rapid response capability. In the EU project AniBioThreat, early warning is the main topic in work package 3 (WP 3). A strategy has been generated based on an iterative approach to bring law enforcement agencies and human and animal health institutes together. Workshops and exercises have taken place during the first half of the project, and spin-off activities include new preparedness plans for institutes and the formation of a legal adviser network for decision making. In addition, a seminar on actionable knowledge was held in Stockholm, Sweden, in 2012, which identified the need to bring various agency cultures together to work on developing a resilient capability to identify early signs of bio- and agroterrorism threats. The seminar concluded that there are a number of challenges in building a collaborative culture, including developing an education program that supports collaboration and shared situational awareness.

Establishment of CDC Global Rapid Response Team to Ensure Global Health Security.

PubMed

Stehling-Ariza, Tasha; Lefevre, Adrienne; Calles, Dinorah; Djawe, Kpandja; Garfield, Richard; Gerber, Michael; Ghiselli, Margherita; Giese, Coralie; Greiner, Ashley L; Hoffman, Adela; Miller, Leigh Ann; Moorhouse, Lisa; Navarro-Colorado, Carlos; Walsh, James; Bugli, Dante; Shahpar, Cyrus

2017-12-01

The 2014-2016 Ebola virus disease epidemic in West Africa highlighted challenges faced by the global response to a large public health emergency. Consequently, the US Centers for Disease Control and Prevention established the Global Rapid Response Team (GRRT) to strengthen emergency response capacity to global health threats, thereby ensuring global health security. Dedicated GRRT staff can be rapidly mobilized for extended missions, improving partner coordination and the continuity of response operations. A large, agencywide roster of surge staff enables rapid mobilization of qualified responders with wide-ranging experience and expertise. Team members are offered emergency response training, technical training, foreign language training, and responder readiness support. Recent response missions illustrate the breadth of support the team provides. GRRT serves as a model for other countries and is committed to strengthening emergency response capacity to respond to outbreaks and emergencies worldwide, thereby enhancing global health security.

Unique Education and Workforce Development for NASA Engineers

NASA Technical Reports Server (NTRS)

Forsgren, Roger C.; Miller, Lauren L.

2010-01-01

NASA engineers are some of the world's best-educated graduates, responsible for technically complex, highly significant scientific programs. Even though these professionals are highly proficient in traditional analytical competencies, there is a unique opportunity to offer continuing education that further enhances their overall scientific minds. With a goal of maintaining the Agency's passionate, "best in class" engineering workforce, the NASA Academy of Program/Project & Engineering Leadership (APPEL) provides educational resources encouraging foundational learning, professional development, and knowledge sharing. NASA APPEL is currently partnering with the scientific community's most respected subject matter experts to expand its engineering curriculum beyond the analytics and specialized subsystems in the areas of: understanding NASA's overall vision and its fundamental basis, and the Agency initiatives supporting them; sharing NASA's vast reservoir of engineering experience, wisdom, and lessons learned; and innovatively designing hardware for manufacturability, assembly, and servicing. It takes collaboration and innovation to educate an organization that possesses such a rich and important historyand a future that is of great global interest. NASA APPEL strives to intellectually nurture the Agency's technical professionals, build its capacity for future performance, and exemplify its core valuesalJ to better enable NASA to meet its strategic visionand beyond.

Financial risk sharing with providers in health maintenance organizations, 1999.

PubMed

Gold, Marsha R; Lake, Timothy; Hurley, Robert; Sinclair, Michael

2002-01-01

The transfer of financial risk from health maintenance organizations (HMOs) to providers is controversial. To provide timely national data on these practices, we conducted a telephone survey in 1999 of a multi-staged probability sample of HMOs in 20 of the nation's 60 largest markets, accounting for 86% of all HMO enrollees nationally. Among those sampled, 82% responded. We found that HMOs' provider networks with physicians, hospitals, skilled nursing homes, and home health agencies are complex and multi-tiered Seventy-six percent of HMOs in our study use contracts for their HMO products that involve global, professional services, or hospital risk capitation to intermediate entities. These arrangements account for between 24.5 million and 27.4 million of the 55.9 million commercial and Medicare HMO enrollees in the 60 largest markets. While capitation arrangements are particularly common in California, they are more common elsewhere than many assume. The complex layering of risk sharing and delegation of care management responsibility raise questions about accountability and administrative costs in managed care. Do complex structures provide a way to involve providers more directly in managed care, or do they diffuse authority and add to administrative costs?

International Guidelines for Privacy in Genomic Biobanking (or the Unexpected Virtue of Pluralism).

PubMed

Thorogood, Adrian; Zawati, Ma'n H

2015-01-01

This article reviews international privacy norms governing human genomic biobanks and databases, and how they address issues related to consent, secondary use, de- identification, access, security, and governance. A range of international instruments were identified, varying in substance - e.g., human rights, data protection, research ethics, biobanks, and genetics - and legal character. Some norms detail processes for broad consent, namely, that even where potential participants cannot consent to specific users and uses, they should be given clear information on access policies, procedures, and governance structures. Some also give guidance about the conditions under which secondary use of data and samples without consent is appropriate, e.g., where consent is impracticable. International norms exhibit a confusing range of terminology relating to de-identification. They also continue to rely heavily on consent and anonymity as the basis for privacy protection, though governance is becoming more prominent. It may not be fatal that such a plurality of norms apply to biobanking; what is essential is that governance be built on shared values, our common interest in the success of genomic research, and practical tools that incentivize responsible, global sharing. © 2015 American Society of Law, Medicine & Ethics, Inc.

Correlations Between Extreme Atmospheric Hazards and Global Teleconnections: Implications for Multihazard Resilience

NASA Astrophysics Data System (ADS)

Steptoe, H.; Jones, S. E. O.; Fox, H.

2018-03-01

Occurrences of concurrent extreme atmospheric hazards represent a significant area of uncertainty for organizations involved in disaster mitigation and risk management. Understanding risks posed by natural disasters and their relationship with global climate drivers is crucial in preparing for extreme events. In this review we quantify the strength of the physical mechanisms linking hazards and atmosphere-ocean processes. We demonstrate how research from the science community may be used to support disaster risk reduction and global sustainable development efforts. We examine peer-reviewed literature connecting 16 regions affected by extreme atmospheric hazards and eight key global drivers of weather and climate. We summarize current understanding of multihazard disaster risk in each of these regions and identify aspects of the global climate system that require further investigation to strengthen our resilience in these areas. We show that some drivers can increase the risk of concurrent hazards across different regions. Organizations that support disaster risk reduction, or underwrite exposure, in multiple regions may have a heightened risk of facing multihazard losses. We find that 15 regional hazards share connections via the El Niño-Southern Oscillation, with the Indian Ocean Dipole, North Atlantic Oscillation, and the Southern Annular Mode being secondary sources of significant regional interconnectivity. From a hazard perspective, rainfall over China shares the most connections with global drivers and has links to both Northern and Southern Hemisphere modes of variability. We use these connections to assess the global likelihood of concurrent hazard occurrence in support of multihazard resilience and disaster risk reduction goals.

International Development of e-Infrastructures and Data Management Priorities for Global Change Research

NASA Astrophysics Data System (ADS)

Allison, M. L.; Gurney, R. J.

2015-12-01

An e-infrastructure that supports data-intensive, multidisciplinary research is needed to accelerate the pace of science to address 21st century global change challenges. Data discovery, access, sharing and interoperability collectively form core elements of an emerging shared vision of e-infrastructure for scientific discovery. The pace and breadth of change in information management across the data lifecycle means that no one country or institution can unilaterally provide the leadership and resources required to use data and information effectively, or needed to support a coordinated, global e-infrastructure. An 18-month long process involving ~120 experts in domain, computer, and social sciences from more than a dozen countries resulted in a formal set of recommendations to the Belmont Forum collaboration of national science funding agencies and others on what they are best suited to implement for development of an e-infrastructure in support of global change research, including: adoption of data principles that promote a global, interoperable e-infrastructure establishment of information and data officers for coordination of global data management and e-infrastructure efforts promotion of effective data planning determination of best practices development of a cross-disciplinary training curriculum on data management and curation The Belmont Forum is ideally poised to play a vital and transformative leadership role in establishing a sustained human and technical international data e-infrastructure to support global change research. The international collaborative process that went into forming these recommendations is contributing to national governments and funding agencies and international bodies working together to execute them.

Job sharing at the managerial level.

PubMed

Acorn, S; Williams, J; Dempster, L; Provost, S; McEwan, C

1997-05-01

Job sharing restructures a full-time position-two individuals share the responsibilities and the benefits of the position. If nurses are committed to making it work, this arrangement can succeed at the managerial level.

Global oral health in the framework of the Global Charter for the Public's Health.

PubMed

Lee, Hyewon; Lomazzi, Marta; Lee, Aimee; Bedi, Raman

2018-05-01

Oral diseases are a neglected epidemic affecting all ages globally and can substantially impact overall health and well-being. Even though most oral diseases are preventable and share major risk factors with other non-communicable diseases, integration of oral health into public health systems is still limited in both clinical and health policy perspectives. This Viewpoint aims to highlight oral health from a global health perspective, calling for all public health leaders to advocate for oral health of all. We strongly recommend oral health as an essential part of public health policy and oral health-related activities to be aligned with the Global Charter for the Public's Health Framework.

Linking regional stakeholder scenarios and shared socioeconomic pathways: Quantified West African food and climate futures in a global context.

PubMed

Palazzo, Amanda; Vervoort, Joost M; Mason-D'Croz, Daniel; Rutting, Lucas; Havlík, Petr; Islam, Shahnila; Bayala, Jules; Valin, Hugo; Kadi Kadi, Hamé Abdou; Thornton, Philip; Zougmore, Robert

2017-07-01

The climate change research community's shared socioeconomic pathways (SSPs) are a set of alternative global development scenarios focused on mitigation of and adaptation to climate change. To use these scenarios as a global context that is relevant for policy guidance at regional and national levels, they have to be connected to an exploration of drivers and challenges informed by regional expertise. In this paper, we present scenarios for West Africa developed by regional stakeholders and quantified using two global economic models, GLOBIOM and IMPACT, in interaction with stakeholder-generated narratives and scenario trends and SSP assumptions. We present this process as an example of linking comparable scenarios across levels to increase coherence with global contexts, while presenting insights about the future of agriculture and food security under a range of future drivers including climate change. In these scenarios, strong economic development increases food security and agricultural development. The latter increases crop and livestock productivity leading to an expansion of agricultural area within the region while reducing the land expansion burden elsewhere. In the context of a global economy, West Africa remains a large consumer and producer of a selection of commodities. However, the growth in population coupled with rising incomes leads to increases in the region's imports. For West Africa, climate change is projected to have negative effects on both crop yields and grassland productivity, and a lack of investment may exacerbate these effects. Linking multi-stakeholder regional scenarios to the global SSPs ensures scenarios that are regionally appropriate and useful for policy development as evidenced in the case study, while allowing for a critical link to global contexts.

Development Impact Assessment Highlights Co-benefits of GHG Mitigation Actions

DOE Office of Scientific and Technical Information (OSTI.GOV)

2016-06-01

This EC-LEDS document describes the Development Impact Assessment (DIA) process that explores interactions between development goals and the low emission development strategies. DIA aims to support informed decision-making by considering how policies and programs intended to meet one goal may impact other development priorities. Enhancing Capacity for Low Emission Development Strategies (EC-LEDS) is a flagship U.S. government-led effort that assists countries in developing and implementing LEDS. The program enhances partner country efforts by providing targeting technical assistance and building a shared global knowledge base on LEDS. is a flagship U.S. government-led effort that assists countries in developing and implementing LEDS.more » The program enhances partner country efforts by providing targeting technical assistance and building a shared global knowledge base on LEDS.« less

The role of new information technology meeting the global need and gap of education in pediatric surgery.

PubMed

Ure, Benno; Zoeller, Christoph; Lacher, Martin

2015-06-01

Traditionally, pediatric surgical education consisted of exposure to patients, textbooks, lectures, team-based education, congresses, and workshops. Over the last decades, however, new information technology (IT) and the internet revolutionized the sharing of information and communication. IT has become relevant in particular for the younger generation of pediatric surgeons. Today, gaps in children's health and the quality of pediatric surgical education persist between countries and regions. Advances in health care are not shared equitably. The use of IT for resource libraries, teleconferences, virtual symposiums, and telementoring has great potential in closing this gap and meeting the global needs for pediatric surgical education. This article focuses on the potential role of IT in this respect. Copyright © 2015 Elsevier Inc. All rights reserved.

The Role of Citizen Science in Risk Mitigation and Disaster Response: A Case Study of 2015 Nepalese Earthquake Using OpenStreetMap

NASA Astrophysics Data System (ADS)

Rieger, C.; Byrne, J. M.

2015-12-01

Citizen science includes networks of ordinary people acting as sensors, observing and recording information for science. OpenStreetMap is one such sensor network which empowers citizens to collaboratively produce a global picture from free geographic information. The success of this open source software is extended by the development of freely used open databases for the user community. Participating citizens do not require a high level of skill. Final results are processed by professionals following quality assurance protocols before map information is released. OpenStreetMap is not only the cheapest source of timely maps in many cases but also often the only source. This is particularly true in developing countries. Emergency responses to the recent earthquake in Nepal illustrates the value for rapidly updated geographical information. This includes emergency management, damage assessment, post-disaster response, and future risk mitigation. Local disaster conditions (landslides, road closings, bridge failures, etc.) were documented for local aid workers by citizen scientists working remotely. Satellites and drones provide digital imagery of the disaster zone and OpenStreetMap participants shared the data from locations around the globe. For the Nepal earthquake, OpenStreetMap provided a team of volunteers on the ground through their Humanitarian OpenStreetMap Team (HOT) which contribute data to the disaster response through smartphones and laptops. This, combined with global citizen science efforts, provided immediate geographically useful maps to assist aid workers, including the Red Cross and Canadian DART Team, and the Nepalese government. As of August 2014, almost 1.7 million users provided over 2.5 billion edits to the OpenStreetMap map database. Due to the increased usage of smartphones, GPS-enabled devices, and the growing participation in citizen science projects, data gathering is proving an effective way to contribute as a global citizen. This paper aims to describe the significance of citizen participation in the case of the Nepal earthquake using OpenStreetMap to respond to disasters as well as its role in future risk mitigation.

Population Structure of Pseudocercospora fijiensis in Costa Rica Reveals Shared Haplotype Diversity with Southeast Asian Populations.

PubMed

Saville, Amanda; Charles, Melodi; Chavan, Suchitra; Muñoz, Miguel; Gómez-Alpizar, Luis; Ristaino, Jean Beagle

2017-12-01

Pseudocercospora fijiensis is the causal pathogen of black Sigatoka, a devastating disease of banana that can cause 20 to 80% yield loss in the absence of fungicides in banana crops. The genetic structure of populations of P. fijiensis in Costa Rica was examined and compared with Honduran and global populations to better understand migration patterns and inform management strategies. In total, 118 isolates of P. fijiensis collected from Costa Rica and Honduras from 2010 to 2014 were analyzed using multilocus genotyping of six loci and compared with a previously published global dataset of populations of P. fijiensis. The Costa Rican and Honduran populations shared haplotype diversity with haplotypes from Southeast Asia, Oceania, and the Americas but not Africa for all but one of the six loci studied. Gene flow and shared haplotype diversity was found in Honduran and Costa Rican populations of the pathogen. The data indicate that the haplotypic diversity observed in Costa Rican populations of P. fijiensis is derived from dispersal from initial outbreak sources in Honduras and admixtures between genetically differentiated sources from Southeast Asia, Oceania, and the Americas.

The NASA Soil Moisture Active Passive (SMAP) Mission: Overview

NASA Technical Reports Server (NTRS)

O'Neill, Peggy; Entekhabi, Dara; Njoku, Eni; Kellogg, Kent

2011-01-01

The Soil Moisture Active Passive (SMAP) mission is one of the first Earth observation satellites being developed by NASA in response to the National Research Council?s Decadal Survey [1]. Its mission design consists of L-band radiometer and radar instruments sharing a rotating 6-m mesh reflector antenna to provide high-resolution and high-accuracy global maps of soil moisture and freeze/thaw state every 2-3 days. The combined active/passive microwave soil moisture product will have a spatial resolution of 10 km and a mean latency of 24 hours. In addition, the SMAP surface observations will be combined with advanced modeling and data assimilation to provide deeper root zone soil moisture and net ecosystem exchange of carbon. SMAP is expected to launch in the late 2014 - early 2015 time frame.

Human Rights Education and Training for Professionals

NASA Astrophysics Data System (ADS)

Andreopoulos, George

2002-07-01

Although human rights education (HRE) has a long history, it has only recently begun to realize its transformative potential. A critical catalyst in this process is the emerging global ethos of accountability. Within this context, HRE can play a crucial role in the construction of a universal culture of human rights, inspired by a shared commitment to a humane order and a belief that human beings have both the capacity and the responsibility to make a difference. In such an effort, the training of professionals is vital, especially of those professionals who can influence public debate on accountability and governance. Innovative HRE initiatives, characterized by a commitment to experiential learning and to international and regional cooperation among state and non-state actors, constitute a step in the right direction.

Job Sharing in the Public Sector.

ERIC Educational Resources Information Center

Olmsted, Barney; And Others

Job sharing is defined as "two people sharing the responsibilities of one full-time position with salary and benefits prorated"; the concept focuses on positions usually offered only as full-time jobs, often in professional and managerial categories. This book presents an overview of current job sharing and permanent part-time employment…

Privacy-Preserving Predictive Modeling: Harmonization of Contextual Embeddings From Different Sources.

PubMed

Huang, Yingxiang; Lee, Junghye; Wang, Shuang; Sun, Jimeng; Liu, Hongfang; Jiang, Xiaoqian

2018-05-16

Data sharing has been a big challenge in biomedical informatics because of privacy concerns. Contextual embedding models have demonstrated a very strong representative capability to describe medical concepts (and their context), and they have shown promise as an alternative way to support deep-learning applications without the need to disclose original data. However, contextual embedding models acquired from individual hospitals cannot be directly combined because their embedding spaces are different, and naive pooling renders combined embeddings useless. The aim of this study was to present a novel approach to address these issues and to promote sharing representation without sharing data. Without sacrificing privacy, we also aimed to build a global model from representations learned from local private data and synchronize information from multiple sources. We propose a methodology that harmonizes different local contextual embeddings into a global model. We used Word2Vec to generate contextual embeddings from each source and Procrustes to fuse different vector models into one common space by using a list of corresponding pairs as anchor points. We performed prediction analysis with harmonized embeddings. We used sequential medical events extracted from the Medical Information Mart for Intensive Care III database to evaluate the proposed methodology in predicting the next likely diagnosis of a new patient using either structured data or unstructured data. Under different experimental scenarios, we confirmed that the global model built from harmonized local models achieves a more accurate prediction than local models and global models built from naive pooling. Such aggregation of local models using our unique harmonization can serve as the proxy for a global model, combining information from a wide range of institutions and information sources. It allows information unique to a certain hospital to become available to other sites, increasing the fluidity of information flow in health care. ©Yingxiang Huang, Junghye Lee, Shuang Wang, Jimeng Sun, Hongfang Liu, Xiaoqian Jiang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 16.05.2018.

Comparison of historical medical spending patterns among the BRICS and G7.

PubMed

Jakovljevic, Mihajlo Michael

2016-01-01

The past few decades have been marked by a bold increase in national health spending across the globe. Rather successful health reforms in leading emerging markets such as BRICS reveal a reshaping of their medical care-related expenditures. There is a scarcity of evidence explaining differences in long-term medical spending patterns between top ranked G7 traditional welfare economies and the BRICS nations. A retrospective observational study was conducted on a longitudinal WHO Global Health Expenditure data-set based on the National Health Accounts (NHA) system. Data were presented in a simple descriptive manner, pointing out health expenditure dynamics and differences between the two country groups (BRICS and G7) and individual nations in a 1995-2013 time horizon. Average total per capita health spending still remains substantially higher among G7 (4747 Purchase Power Parity (PPP) $PPP in 2013) compared to the BRICS (1004 $PPP in 2013) nations. The percentage point share of G7 in global health expenditure (million current PPP international $US) has been falling constantly since 1995 (from 65% in 1995 to 53.2% in 2013), while in BRICS nations it grew (from 10.7% in 1995 to 20.2% in 2013). Chinese national level medical spending exceeded significantly that of all G7 members except the US in terms of current $PPP in 2013. Within a limited time horizon of only 19 years it appears that the share of global medical spending by the leading emerging markets has been growing steadily. Simultaneously, the world's richest countries' global share has been falling constantly, although it continues to dominate the landscape. If the contemporary global economic mainstream continues, the BRICS per capita will most likely reach or exceed the OECD average in future decades. Rising out-of-pocket expenses threatening affordability of medical care to poor citizens among the BRICS nations and a too low percentage of GDP in India remain the most notable setbacks of these developments.

Shared maternity care: all care--not enough responsibility? An audit of patient care communications pre- and post- a multi-faceted intervention.

PubMed

Nicolson, Susan; Pirotta, Marie; Chondros, Patty

2005-12-01

Shared maternity care is an important model of care in Australia and overseas, but Victorian studies have shown patient dissatisfaction and widespread communication problems. This study aimed to implement and evaluate initiatives to improve communication between three maternity hospitals and general practitioners involved in shared maternity care in Melbourne. A pre- and post-design with audit of 150 hospital records at each of three hospitals plus audit of 20 general practitioner files for evidence of key communications on shared care patients, before and after a multifaceted intervention. Significant improvements at individual hospitals were seen if one person was made responsible for a communication outcome. Other initiatives did not lead to improvements if they did not include individual accountability. The standard of integration of shared maternity care is unacceptable low. Improvements to communication are achievable but depend on the allocation of individual time and responsibility, plus a commitment by hospitals to ongoing audit of their performance.

Performance Assessment Assistance Activities in the DOE Complex - 12325

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seitz, Roger R.; Phifer, Mark A.; Letourneau, Martin J.

The United States Department of Energy Office of Environmental Management (DOE-EM) has established a Performance Assessment Community of Practice (PA CoP) to foster the sharing of information among performance assessment (PA) and risk assessment practitioners, regulators and oversight personnel. The general intent is to contribute to continuous improvement in the consistency, technical adequacy and quality of implementation of PAs and risk assessments around the DOE Complex. The PA CoP activities have involved commercial disposal facilities and international participants to provide a global perspective. The PA CoP has also sponsored annual technical exchanges as a means to foster improved communication andmore » to share lessons learned from on-going modelling activities. The PA CoP encourages activities to provide programmatic and technical assistance in the form of sharing experience and lessons learned with practitioners during the development of PAs and risk assessments. This assistance complements DOE-EM reviews through the Low-Level Waste Disposal Facility Federal Review Group (LFRG) that are conducted after modelling efforts are completed. Such up-front assistance is providing additional value in terms of improving consistency and sharing of information. There has been a substantial increase in the amount of assistance being provided. The assistance has been well received by practitioners and regulators that have been involved. The paper highlights assistance and sharing of information that has been conducted in the last two years to support activities underway in support of proposed disposal facilities at Paducah, Portsmouth, and the Idaho National Laboratory and tank closure at Hanford. DOE-EM established the PA CoP to help improve the consistency and quality of implementation of modelling activities around the DOE Complex. The PA CoP has sponsored annual technical exchanges as a means to foster improved communication and to share lessons learned from ongoing modelling activities. Practitioners; project managers; oversight personnel; and regulators from United States and international facilities have participated in the three technical exchanges that have been held to date. At the working level, the PA CoP has sponsored technical assistance in support of modelling activities that are currently underway. The assistance concept provides a means to share specific experience, good practices, and lessons learned on topics of interest at a given site while the modelling is being conducted. Such up-front assistance complements the sharing of information that occurs via regular LFRG meetings and independent LFRG reviews that are conducted when the modelling effort is completed. Examples from assistance activities that have been conducted at Idaho, Paducah, Portsmouth and Hanford were highlighted in this paper. There were differences in the types of assistance provided at each site. In some cases the assistance was focused on technical support for the practitioners and management responsible for the development of the PAs. At other sites, the assistance included working with the developers and regulators/stakeholders involved in the process to help with reaching consensus on critical assumptions. Such interactions have proven to be very effective to help all parties get a chance to discuss their perspectives and better understand the different points of view. In all cases, the assistance was used as a means to share broader perspectives, experiences and lessons learned with personnel engaged in a modelling activities at a given site. The combination of technical exchanges and targeted technical assistance has provided additional means to encourage the sharing of information around the DOE Complex and globally. Feedback from practitioners, oversight personnel, regulators and stakeholders that have been involved has been overwhelmingly positive. It is believed that such sharing of information and experiences is contributing to continuous improvement in the consistency, technical adequacy, and quality of modelling activities. Although different approaches are still being used, there is an improvement in the awareness of lessons learned and implementation of practices that have proven to be effective. (authors)« less

Assessing the impacts of 1.5 °C global warming - simulation protocol of the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP2b)

NASA Astrophysics Data System (ADS)

Frieler, Katja; Lange, Stefan; Piontek, Franziska; Reyer, Christopher P. O.; Schewe, Jacob; Warszawski, Lila; Zhao, Fang; Chini, Louise; Denvil, Sebastien; Emanuel, Kerry; Geiger, Tobias; Halladay, Kate; Hurtt, George; Mengel, Matthias; Murakami, Daisuke; Ostberg, Sebastian; Popp, Alexander; Riva, Riccardo; Stevanovic, Miodrag; Suzuki, Tatsuo; Volkholz, Jan; Burke, Eleanor; Ciais, Philippe; Ebi, Kristie; Eddy, Tyler D.; Elliott, Joshua; Galbraith, Eric; Gosling, Simon N.; Hattermann, Fred; Hickler, Thomas; Hinkel, Jochen; Hof, Christian; Huber, Veronika; Jägermeyr, Jonas; Krysanova, Valentina; Marcé, Rafael; Müller Schmied, Hannes; Mouratiadou, Ioanna; Pierson, Don; Tittensor, Derek P.; Vautard, Robert; van Vliet, Michelle; Biber, Matthias F.; Betts, Richard A.; Bodirsky, Benjamin Leon; Deryng, Delphine; Frolking, Steve; Jones, Chris D.; Lotze, Heike K.; Lotze-Campen, Hermann; Sahajpal, Ritvik; Thonicke, Kirsten; Tian, Hanqin; Yamagata, Yoshiki

2017-11-01

In Paris, France, December 2015, the Conference of the Parties (COP) to the United Nations Framework Convention on Climate Change (UNFCCC) invited the Intergovernmental Panel on Climate Change (IPCC) to provide a special report in 2018 on the impacts of global warming of 1.5 °C above pre-industrial levels and related global greenhouse gas emission pathways. In Nairobi, Kenya, April 2016, the IPCC panel accepted the invitation. Here we describe the response devised within the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) to provide tailored, cross-sectorally consistent impact projections to broaden the scientific basis for the report. The simulation protocol is designed to allow for (1) separation of the impacts of historical warming starting from pre-industrial conditions from impacts of other drivers such as historical land-use changes (based on pre-industrial and historical impact model simulations); (2) quantification of the impacts of additional warming up to 1.5 °C, including a potential overshoot and long-term impacts up to 2299, and comparison to higher levels of global mean temperature change (based on the low-emissions Representative Concentration Pathway RCP2.6 and a no-mitigation pathway RCP6.0) with socio-economic conditions fixed at 2005 levels; and (3) assessment of the climate effects based on the same climate scenarios while accounting for simultaneous changes in socio-economic conditions following the middle-of-the-road Shared Socioeconomic Pathway (SSP2, Fricko et al., 2016) and in particular differential bioenergy requirements associated with the transformation of the energy system to comply with RCP2.6 compared to RCP6.0. With the aim of providing the scientific basis for an aggregation of impacts across sectors and analysis of cross-sectoral interactions that may dampen or amplify sectoral impacts, the protocol is designed to facilitate consistent impact projections from a range of impact models across different sectors (global and regional hydrology, lakes, global crops, global vegetation, regional forests, global and regional marine ecosystems and fisheries, global and regional coastal infrastructure, energy supply and demand, temperature-related mortality, and global terrestrial biodiversity).

Effects of cloudiness on global and diffuse UV irradiance in a high-mountain area

NASA Astrophysics Data System (ADS)

Blumthaler, M.; Ambach, W.; Salzgeber, M.

1994-03-01

At the high-mountain station Jungfraujoch (3576 m a.s.l., Switzerland), measurements of the radiation fluxes were made during 16 periods of six to eight weeks by means of a Robertson—Berger sunburn meter (UVB data), an Eppley UVA radiometer and an Eppley pyranometer. Cloudiness, opacity and altitude of clouds were recorded at 30-minute intervals. A second set of instruments was employed for separate measurement of the diffuse radiation fluxes using shadow bands. The global and diffuse UVA- and UVB radiation fluxes change less with cloudiness than the corresponding total radiation fluxes. When the sun is covered by clouds, the global UVA- and UVB radiation fluxes are also affected less than the global total radiation flux. The roughly equal influence of cloudiness on the UVA- and UVB radiation fluxes suggests that the reduction is influenced more by scattering than by ozone. Also, the share of diffuse irradiance in global irradiance is considerably higher for UVA- and UVB irradiance than for total irradiance. At 50° solar elevation and 0/10 cloudiness, the share is 39% for UVB irradiance, 34% for UVA irradiance and 11% for total irradiance. The increased aerosol turbidity after the eruptions of El Chichon and Pinatubo has caused a significant increase in diffuse total irradiance but has not produced any significant changes in diffuse UVA- and UVB irradiances.

Global Conflicts Shattered World Peace: John Dewey's Influence on Peace Educators and Practitioners

ERIC Educational Resources Information Center

Cohan, Audrey; Howlett, Charles F.

2017-01-01

The need to build an awareness of peace and of peace education is often a message that is difficult to share with the larger society. John Dewey, an acclaimed American philosopher and intellectual, used his public platform to espouse his ideas on democracy and peace as a resolution to global discord during the years preceding and during World Wars…

Global Governance 2025: At a Critical Juncture

DTIC Science & Technology

2010-09-01

them. Formal institutions remain largely unreformed and Western states probably must shoulder a disproportionate share of “global governance” as...might be in a better position but may still be fiscally constrained if its budgetary shortfalls and long-term debt problems remain unresolved...that undermine both the environment and investment. Reliance on domestic reserves of fossil fuels or long- term access to foreign fields makes

Fairly sustainable forestry: seven key concepts for defining local sustainability in a global ecosystem

Treesearch

Stephen R. Shifley

2008-01-01

In the U.S. we increasingly restrict wood production in the name of sustainability while going abroad for a growing share of the wood we consume, even though our own forest resources per capita are far greater than the global average. The unintended consequence is that we transfer impacts (positive and negative) of our timber harvesting and wood consumption to other...

Leadership outside the Box: The Power of Nurturing the Human Spirit at Work in an Era of Globalization

ERIC Educational Resources Information Center

Rutigliano, Nancy Kymn Harvin; Frye, Alexandria S.

2015-01-01

The human spirit is an untapped resource that can fuel organizations in this era of globalization. While workplace spirituality is often seen as an abstract philosophical construct that may be defined differently by each individual who studies it, fulfillment at work, shared values and sense of meaning along with a sense of belonging or…

Regaining Legitimacy in the Context of Global Governance? UNESCO, Education for All Coordination and the Global Monitoring Report

ERIC Educational Resources Information Center

Edwards, D. Brent, Jr.; Okitsu, Taeko; da Costa, Romina; Kitamura, Yuto

2017-01-01

This research note shares insights which resulted from a larger study into the ways in which the United Nations Educational, Scientific and Cultural Organization (UNESCO)--during 2010-2014--used its position as coordinator of the post-Dakar Framework for Action (initiated at the World Education Forum held in 2000 and designed to reinvigorate the…

Assessing the Effects of Financial Literacy on Patient Engagement.

PubMed

Meyer, Melanie A; Hudak, Ronald P

2016-07-01

We investigated the relationship between financial literacy and patient engagement while considering the possible interaction effects due to patient financial responsibility and patient-physician shared decision making, and the impact of personal attributes. Participants consisted of an Internet-based sample of American adults (N = 160). Hierarchical multiple linear regression analysis was conducted to examine the relationship of the study variables on patient engagement. We found that patient financial responsibility (β = -.19, p < .05) and patient-physician shared decision-making (β = .17, p < .05) predicted patient engagement. However, there was no statistically significant relationship between patient financial literacy and patient engagement; moreover, the moderation effects of patient financial responsibility and shared decision making with financial literacy also were not statistically significant. Increasing patient financial responsibility and patient-physician shared decision making can impact patient engagement. Understanding the predictors of patient engagement and the factors that influence financial behaviors may allow for the development of interventions to enable patients to make better healthcare decisions, and ultimately, improve health outcomes.

Major multinational food and beverage companies and informal sector contributions to global food consumption: implications for nutrition policy.

PubMed

Alexander, Eleanore; Yach, Derek; Mensah, George A

2011-08-01

In recent years, 10 major multinational food and beverage companies have worked together within the International Food and Beverage Alliance (IFBA) to increase their commitments to public health. Current IFBA commitments include initiatives to improve the nutrition quality of products and how these products are advertised to children. The impact and magnitude of IFBA member contributions to the total market share of packaged foods and beverages consumed remain incompletely understood, however. In order to evaluate this impact, we examined packaged food and soft drink company shares provided by Euromonitor, an international independent market analysis company. Packaged foods include baby food, bakery, canned/preserved food, chilled/processed food, confectionery, dairy, dried processed food, frozen processed food, ice cream, meal replacement, noodles, oils and fats, pasta, ready meals, sauces, dressings and condiments, snack bars, soup, spreads, and sweet and savoury snacks. Soft drinks include carbonates, packaged fruit/vegetable juice, bottled water, functional drinks, concentrates, ready-to-drink tea, ready-to-drink coffee and Asian specialty drinks. We calculated the market shares for IFBA companies, globally and within nine countries--the US, China, India, Egypt, South Africa, Brazil, Mexico, Turkey and the UK. Worldwide, the top ten packaged food companies account for 15.2% of sales, with each individual company contributing less than 3.3%. The top ten soft drink companies account for 52.3% of sales worldwide; Coca-Cola and PepsiCo lead with 25.9% and 11.5% of sales, respectively. Although the top ten soft drink companies account for half of global sales, the top ten packaged food companies account for only a small proportion of market share with most individual companies contributing less than 3.3% each. Major multinational companies need to be joined by the myriad of small- and medium-sized enterprises in developing and implementing programs to improve the health of the public, globally. Without full participation of these companies, the impact of commitments made by IFBA members and other major multinational food and beverage companies will remain limited.

Major multinational food and beverage companies and informal sector contributions to global food consumption: implications for nutrition policy

PubMed Central

2011-01-01

Background In recent years, 10 major multinational food and beverage companies have worked together within the International Food and Beverage Alliance (IFBA) to increase their commitments to public health. Current IFBA commitments include initiatives to improve the nutrition quality of products and how these products are advertised to children. The impact and magnitude of IFBA member contributions to the total market share of packaged foods and beverages consumed remain incompletely understood, however. Methods In order to evaluate this impact, we examined packaged food and soft drink company shares provided by Euromonitor, an international independent market analysis company. Packaged foods include baby food, bakery, canned/preserved food, chilled/processed food, confectionery, dairy, dried processed food, frozen processed food, ice cream, meal replacement, noodles, oils and fats, pasta, ready meals, sauces, dressings and condiments, snack bars, soup, spreads, and sweet and savoury snacks. Soft drinks include carbonates, packaged fruit/vegetable juice, bottled water, functional drinks, concentrates, ready-to-drink tea, ready-to-drink coffee and Asian specialty drinks. We calculated the market shares for IFBA companies, globally and within nine countries--the US, China, India, Egypt, South Africa, Brazil, Mexico, Turkey and the UK. Results Worldwide, the top ten packaged food companies account for 15.2% of sales, with each individual company contributing less than 3.3%. The top ten soft drink companies account for 52.3% of sales worldwide; Coca-Cola and PepsiCo lead with 25.9% and 11.5% of sales, respectively. Conclusions Although the top ten soft drink companies account for half of global sales, the top ten packaged food companies account for only a small proportion of market share with most individual companies contributing less than 3.3% each. Major multinational companies need to be joined by the myriad of small- and medium-sized enterprises in developing and implementing programs to improve the health of the public, globally. Without full participation of these companies, the impact of commitments made by IFBA members and other major multinational food and beverage companies will remain limited. PMID:21806827

Health Professional Workforce Education in the Asia Pacific

PubMed Central

Lees, Jessica; Webb, Gillian; Coulston, Frances; Smart, Aidan; Remedios, Louisa

2016-01-01

Objective To design and implement an international and interprofessional Global Learning Partnership Model, which involves shared learning between academics and students from Universitas 21 network with other universities with United Nations Millennium Development Goal needs. Design Two literature reviews were conducted to inform ethical aspects and curriculum design of the GLP model. Feedback from conference presentations and consultation with experts in education and public health has been incorporated to inform the current iteration of the GLP model. Intervention The pilot group of 25 students from U21 universities and Kathmandu University, representing six health disciplines will meet in Nepal in April 2016 for a shared learning experience, including a one week university based workshop and three week community based experience. Outcome measures A multi-phase, mixed method design was selected for the evaluation of the GLP model, utilising a combination of focus groups and questionnaires to evaluate the efficacy of the placement through student experience and learning outcomes in cultural competency, UN SDG knowledge, community engagement and health promotion skills. Results The literature review demonstrated that cultural awareness and cultural knowledge were improved through participation in cultural immersion programs that incorporated preparatory workshops and clinical experiences. Data will be gathered in April 2006 and the results of the evaluation will be published in the future. Conclusions The GLP model proposes a project around the fundamental concept of engagement and sharing between students and academics across universities and cultural contexts to build capacity through education, while capitalising on strengths of existing global health placements. Further the inclusion of host-country students and academics in this learning exchange will promote the establishment of an international and interprofessional network for ongoing health promotion. Significance for public health The Global Learning Partnership model aims to contribute to the capacity building of a health workforce that is capable of working effectively in cross cultural and interprofessional health care teams. A shared public health focused global placement has the potential to catalyse collaborative relationships between educational institutions in the Asia Pacific region. PMID:27190976

Industry Contributions to Seafloor Mapping: Building Partnerships for Collecting, Sharing, and Compiling Data

NASA Astrophysics Data System (ADS)

Brumley, K. J.; Mitchell, G. A.; Millar, D.; Saade, E. J.; Gharib, J. J.

2017-12-01

In an effort to map the remaining 85% of the worlds seafloor, The Nippon Foundation and GEBCO have launched Seabed 2030 to provide high-resolution bathymetry for all ocean waters by the year 2030. This ambitious effort will require sharing of bathymetric information to build a global baseline bathymetry database. Multibeam echosounder (MBES) data is a promising source of data for Seabed 2030. These data benefit multiple users which includes not only bathymetric information, but also valuable backscatter data, useful for determining seafloor characteristics), as well as water column data, which can be used to explore other aspects of the marine environment and potentially help constrain some of the ocean's methane flux estimates. Fugro provides global survey services for clients in the oil and gas, telecommunications, infrastructure industries, and state and federal agencies. With a global fleet of survey vessels and autonomous vehicles equipped with state-of-the-art MBES systems, Fugro has performed some of the world's largest offshore surveys over the past several years mapping close to 1,000,000 km2 of seafloor per year with high-resolution MBES data using multi-vessel operational models and new methods for merging datasets from different multibeam sonar systems. Although most of these data are proprietary, Fugro is working with clients in the private-sector to make data available to the Seabed 2030 project at a decimated resolution of 100 m. The company is also contributing the MBES data acquired during transits to survey locations. Fugro has also partnered with Shell Ocean Discovery XPRIZE to support development of new rapid, unmanned, high-resolution ocean mapping technologies that can benefit understanding of the world's oceans. Collaborative approaches such as these are helping to establish a new standard for other industry contributions, and to facilitate a new outlook for data sharing among the public and private sectors. Recognizing the importance of an open-sourced global bathymetric dataset, we will discuss our initial efforts to contribute to the Seabed 2030 program from an industry perspective, share new techniques in survey operations for surveying large areas of the seafloor, and show geologic discoveries from various recent very large-scale MBES surveys.

Notes on a Vision for the Global Space Weather Enterprise

NASA Astrophysics Data System (ADS)

Head, James N.

2015-07-01

Space weather phenomena impacts human civilization on a global scale and hence calls for a global approach to research, monitoring, and operational forecasting. The Global Space Weather Enterprise (GSWE) could be arranged along lines well established in existing international frameworks related to space exploration or to the use of space to benefit humanity. The Enterprise need not establish a new organization, but could evolve from existing international organizations. A GSWE employing open architectural concepts could be arranged to promote participation by all interested States regardless of current differences in science and technical capacity. Such an Enterprise would engender capacity building and burden sharing opportunities.

Building the Nightingale Initiative for Global Health--NIGH: can we engage and empower the public voices of nurses worldwide?

PubMed

Beck, Deva-Marie; Dossey, Barbara M; Rushton, Cynda H

2013-10-01

The Nightingale Initiative for Global Health (NIGH) is a major grassroots-to-global movement of "daring, caring and sharing" of nursing and others around the world inspired by the outstanding legacy of Florence Nightingale. The Nightingale Initiative envisions and emulates what Nightingale might have accomplished if she lived in the digital age and with international agencies such as the United Nations and World Health Organization. It challenges nurses everywhere to think and act both locally and globally, to raise their voices about the contribution of nursing, and to become authentic advocates, particularly in addressing the United Nations Millennium Development Goals.

Attitudes of research participants and the general public towards genomic data sharing: a systematic literature review.

PubMed

Shabani, Mahsa; Bezuidenhout, Louise; Borry, Pascal

2014-11-01

Introducing data sharing practices into the genomic research arena has challenged the current mechanisms established to protect rights of individuals and triggered policy considerations. To inform such policy deliberations, soliciting public and research participants' attitudes with respect to genomic data sharing is a necessity. The main electronic databases were searched in order to retrieve empirical studies, investigating the attitudes of research participants and the public towards genomic data sharing through public databases. In the 15 included studies, participants' attitudes towards genomic data sharing revealed the influence of a constellation of interrelated factors, including the personal perceptions of controllability and sensitivity of data, potential risks and benefits of data sharing at individual and social level and also governance level considerations. This analysis indicates that future policy responses and recruitment practices should be attentive to a wide variety of concerns in order to promote both responsible and progressive research.

Study on generation and sharing of on-demand global seamless data—Taking MODIS NDVI as an example

NASA Astrophysics Data System (ADS)

Shen, Dayong; Deng, Meixia; Di, Liping; Han, Weiguo; Peng, Chunming; Yagci, Ali Levent; Yu, Genong; Chen, Zeqiang

2013-04-01

By applying advanced Geospatial Data Abstraction Library (GDAL) and BigTIFF technology in a Geographical Information System (GIS) with Service Oriented Architecture (SOA), this study has derived global datasets using tile-based input data and implemented Virtual Web Map Service (VWMS) and Virtual Web Coverage Service (VWCS) to provide software tools for visualization and acquisition of global data. Taking MODIS Normalized Difference Vegetation Index (NDVI) as an example, this study proves the feasibility, efficiency and features of the proposed approach.

Solutions to Faculty Work Overload: A Study of Job Sharing

ERIC Educational Resources Information Center

Freeman, Brenda J.; Coll, Kenneth M.

2009-01-01

This study investigated the opinions of a national sample of counselor education chairs and college of education deans regarding the advantages and disadvantages of faculty job sharing. Results showed favorable responses toward faculty job sharing from approximately half the sample, despite limited experience with job sharing. The study found few…

The Role of Civil Society Organizations in Monitoring the Global AIDS Response.

PubMed

Smith, Julia; Mallouris, Christoforos; Lee, Kelley; Alfvén, Tobias

2017-07-01

Civil society organizations (CSOs) are recognized as playing an exceptional role in the global AIDS response. However, there is little detailed research to date on how they contribute to specific governance functions. This article uses Haas' framework on global governance functions to map CSO's participation in the monitoring of global commitments to the AIDS response by institutions and states. Drawing on key informant interviews and primary documents, it focuses specifically on CSO participation in Global AIDS Response Progress Reporting and in Global Fund to Fight AIDS, Tuberculosis and Malaria processes. It argues that the AIDS response is unique within global health governance, in that CSOs fulfill both formal and informal monitoring functions, and considers the strengths and weaknesses of these contributions. It concludes that future global health governance arrangements should include provisions and resources for monitoring by CSOs because their participation creates more inclusive global health governance and contributes to strengthening commitments to human rights.

Challenges and Path Forward on Mandatory Allergen Labeling and Voluntary Precautionary Allergen Labeling for a Global Company.

PubMed

Yeung, Jupiter; Robert, Marie-Claude

2018-01-01

For food manufacturers, the label on a food package is a tool meant to alert consumers to the presence of specific allergens, allowing consumers to make informed decisions and not unnecessarily limit their food choices. Mandatory allergen labeling is used when the allergen is an intentionally added ingredient, whereas voluntary allergen labeling is used when the presence of the allergen is unintentional and may be in the finished product as a result of cross-contact. In a globalized economy, ensuring food safety is a growing challenge for manufacturers. When ingredients and technologies are sourced worldwide from multiple business partners, complexity rises, which can increase the chance for errors, leading to potential harm. Threshold science, Voluntary Incidental Trace Allergen Labelling (VITAL) reference doses, fit-for-purpose analytical technology, and common sense enable us to optimize allergen management for the benefit of allergic consumers. This is a good strategy because all stakeholders share the common goal of making foods safe and wholesome for all. Herein, we recommend that (1) senior management make science-based thresholds a priority for both regulatory authorities and the food industry; (2) VITAL 2.0 be adopted as a risk assessment and risk management tool for precautionary allergen labeling (PAL); (3) a standardized message for PAL, i.e., "may contain x," be used to make it easily understandable to allergic consumers so they can make informed food choices; and (4) validated fit-for-purpose allergen methods be used to meet analytical needs. This is an opportunity for us to speak with one voice and demonstrate that food safety is not a competitive issue, but a shared responsibility. This approach could significantly improve allergic consumers' lives.

National poverty reduction strategies and HIV/AIDS governance in Malawi: a preliminary study of shared health governance.

PubMed

Wachira, Catherine; Ruger, Jennifer Prah

2011-06-01

The public health and development communities understand clearly the need to integrate anti-poverty efforts with HIV/AIDS programs. This article reports findings about the impact of the Poverty Reduction Strategy Paper (PRSP) process on Malawi's National HIV/AIDS Strategic Framework (NSF). In this article we ask, how does the PRSP process support NSF accountability, participation, access to information, funding, resource planning and allocation, monitoring, and evaluation? In 2007, we developed and conducted a survey of Malawian government ministries, United Nations agencies, members of the Country Coordination Mechanism, the Malawi National AIDS Commission (NAC), and NAC grantees (N = 125, 90% response rate), seeking survey respondents' retrospective perceptions of NSF resource levels, participation, inclusion, and governance before, during, and after Malawi's PRSP process (2000-2004). We also assessed principle health sector and economic indicators and budget allocations for HIV/AIDS. These indicators are part of a new conceptual framework called shared health governance (SHG), which seeks congruence among the values and goals of different groups and actors to reflect a common purpose. Under this framework, global health policy should encompass: (i) consensus among global, national, and sub-national actors on goals and measurable outcomes; (ii) mutual collective accountability; and (iii) enhancement of individual and group health agency. Indicators to assess these elements included: (i) goal alignment; (ii) adequate resource levels; (iii) agreement on key outcomes and indicators for evaluating those outcomes; (iv) meaningful inclusion and participation of groups and institutions; (v) special efforts to ensure participation of vulnerable groups; and (vi) effectiveness and efficiency measures. Results suggest that the PRSP process supported accountability for NSF resources. However, the process may have marginalized key stakeholders, potentially undercutting the implementation of HIV/AIDS Action Plans. Copyright © 2010. Published by Elsevier Ltd.

Motion coherence affects human perception and pursuit similarly.

PubMed

Beutter, B R; Stone, L S

2000-01-01

Pursuit and perception both require accurate information about the motion of objects. Recovering the motion of objects by integrating the motion of their components is a difficult visual task. Successful integration produces coherent global object motion, while a failure to integrate leaves the incoherent local motions of the components unlinked. We compared the ability of perception and pursuit to perform motion integration by measuring direction judgments and the concomitant eye-movement responses to line-figure parallelograms moving behind stationary rectangular apertures. The apertures were constructed such that only the line segments corresponding to the parallelogram's sides were visible; thus, recovering global motion required the integration of the local segment motion. We investigated several potential motion-integration rules by using stimuli with different object, vector-average, and line-segment terminator-motion directions. We used an oculometric decision rule to directly compare direction discrimination for pursuit and perception. For visible apertures, the percept was a coherent object, and both the pursuit and perceptual performance were close to the object-motion prediction. For invisible apertures, the percept was incoherently moving segments, and both the pursuit and perceptual performance were close to the terminator-motion prediction. Furthermore, both psychometric and oculometric direction thresholds were much higher for invisible apertures than for visible apertures. We constructed a model in which both perception and pursuit are driven by a shared motion-processing stage, with perception having an additional input from an independent static-processing stage. Model simulations were consistent with our perceptual and oculomotor data. Based on these results, we propose the use of pursuit as an objective and continuous measure of perceptual coherence. Our results support the view that pursuit and perception share a common motion-integration stage, perhaps within areas MT or MST.

Shared and divergent pathways for flower abscission are triggered by gibberellic acid and carbon starvation in seedless Vitis vinifera L.

PubMed

Domingos, Sara; Fino, Joana; Cardoso, Vânia; Sánchez, Claudia; Ramalho, José C; Larcher, Roberto; Paulo, Octávio S; Oliveira, Cristina M; Goulao, Luis F

2016-02-01

Abscission is a highly coordinated developmental process by which plants control vegetative and reproductive organs load. Aiming at get new insights on flower abscission regulation, changes in the global transcriptome, metabolome and physiology were analyzed in 'Thompson Seedless' grapevine (Vitis vinifera L.) inflorescences, using gibberellic acid (GAc) spraying and shading as abscission stimuli, applied at bloom. Natural flower drop rates increased from 63.1% in non-treated vines to 83% and 99% in response to GAc and shade treatments, respectively. Both treatments had a broad effect on inflorescences metabolism. Specific impacts from shade included photosynthesis inhibition, associated nutritional stress, carbon/nitrogen imbalance and cell division repression, whereas GAc spraying induced energetic metabolism simultaneously with induction of nucleotide biosynthesis and carbon metabolism, therefore, disclosing alternative mechanisms to regulate abscission. Regarding secondary metabolism, changes in flavonoid metabolism were the most represented metabolic pathways in the samples collected following GAc treatment while phenylpropanoid and stilbenoid related pathways were predominantly affected in the inflorescences by the shade treatment. However, both GAc and shade treated inflorescences revealed also shared pathways, that involved the regulation of putrescine catabolism, the repression of gibberellin biosynthesis, the induction of auxin biosynthesis and the activation of ethylene signaling pathways and antioxidant mechanisms, although often the quantitative changes occurred on specific transcripts and metabolites of the pathways. Globally, the results suggest that chemical and environmental cues induced contrasting effects on inflorescence metabolism, triggering flower abscission by different mechanisms and pinpointing the participation of novel abscission regulators. Grapevine showed to be considered a valid model to study molecular pathways of flower abscission competence acquisition, noticeably responding to independent stimuli.

Motion coherence affects human perception and pursuit similarly

NASA Technical Reports Server (NTRS)

Beutter, B. R.; Stone, L. S.

2000-01-01

Pursuit and perception both require accurate information about the motion of objects. Recovering the motion of objects by integrating the motion of their components is a difficult visual task. Successful integration produces coherent global object motion, while a failure to integrate leaves the incoherent local motions of the components unlinked. We compared the ability of perception and pursuit to perform motion integration by measuring direction judgments and the concomitant eye-movement responses to line-figure parallelograms moving behind stationary rectangular apertures. The apertures were constructed such that only the line segments corresponding to the parallelogram's sides were visible; thus, recovering global motion required the integration of the local segment motion. We investigated several potential motion-integration rules by using stimuli with different object, vector-average, and line-segment terminator-motion directions. We used an oculometric decision rule to directly compare direction discrimination for pursuit and perception. For visible apertures, the percept was a coherent object, and both the pursuit and perceptual performance were close to the object-motion prediction. For invisible apertures, the percept was incoherently moving segments, and both the pursuit and perceptual performance were close to the terminator-motion prediction. Furthermore, both psychometric and oculometric direction thresholds were much higher for invisible apertures than for visible apertures. We constructed a model in which both perception and pursuit are driven by a shared motion-processing stage, with perception having an additional input from an independent static-processing stage. Model simulations were consistent with our perceptual and oculomotor data. Based on these results, we propose the use of pursuit as an objective and continuous measure of perceptual coherence. Our results support the view that pursuit and perception share a common motion-integration stage, perhaps within areas MT or MST.

Eyes wide open: an essay on developing an engaged awareness in global medicine and public health.

PubMed

Ventres, William B; Fort, Meredith P

2014-10-28

There is a growing understanding of the role social determinants such as poverty, gender discrimination, racial prejudice, and economic inequality play on health and illness. While these determinants and effects may be challenging to identify in parts of high-income countries, they are patently obvious in many other areas of the world. How we react to these determinants and effects depends on what historical, cultural, ideological, and psychological characteristics we bring to our encounters with inequity, as well as how our feelings and thoughts inform our values and actions. To address these issues, we share a series of questions we have asked ourselves-United States' citizens with experience living and working in Central America-in relation to our encounters with inequity. We offer a conceptual framework for contemplating responses in hopes of promoting among educators and practitioners in medicine and public health an engaged awareness of how our every day work either perpetuates or breaks down barriers of social difference. We review key moments in our own experiences as global health practitioners to provide context for these questions. Introspective reflection can help professionals in global medicine and public health recognize the dynamic roles that they play in the world. Such reflection can bring us closer to appreciating the forces that have worked both for and in opposition to global health, human rights, and well-being. It can help us recognize how place, time, environment, and context form the social determination of health. It is from this holistic perspective of social relations that we can work to effect fair, equitable, and protective environments as they relate to global medicine and public health.

Effect of the Affordable Medicines Facility--malaria (AMFm) on the availability, price, and market share of quality-assured artemisinin-based combination therapies in seven countries: a before-and-after analysis of outlet survey data.

PubMed

Tougher, Sarah; Ye, Yazoume; Amuasi, John H; Kourgueni, Idrissa A; Thomson, Rebecca; Goodman, Catherine; Mann, Andrea G; Ren, Ruilin; Willey, Barbara A; Adegoke, Catherine A; Amin, Abdinasir; Ansong, Daniel; Bruxvoort, Katia; Diallo, Diadier A; Diap, Graciela; Festo, Charles; Johanes, Boniface; Juma, Elizabeth; Kalolella, Admirabilis; Malam, Oumarou; Mberu, Blessing; Ndiaye, Salif; Nguah, Samuel B; Seydou, Moctar; Taylor, Mark; Rueda, Sergio Torres; Wamukoya, Marilyn; Arnold, Fred; Hanson, Kara

2012-12-01

Malaria is one of the greatest causes of mortality worldwide. Use of the most effective treatments for malaria remains inadequate for those in need, and there is concern over the emergence of resistance to these treatments. In 2010, the Global Fund launched the Affordable Medicines Facility--malaria (AMFm), a series of national-scale pilot programmes designed to increase the access and use of quality-assured artemisinin based combination therapies (QAACTs) and reduce that of artemisinin monotherapies for treatment of malaria. AMFm involves manufacturer price negotiations, subsidies on the manufacturer price of each treatment purchased, and supporting interventions such as communications campaigns. We present findings on the effect of AMFm on QAACT price, availability, and market share, 6-15 months after the delivery of subsidised ACTs in Ghana, Kenya, Madagascar, Niger, Nigeria, Uganda, and Tanzania (including Zanzibar). We did nationally representative baseline and endpoint surveys of public and private sector outlets that stock antimalarial treatments. QAACTs were identified on the basis of the Global Fund's quality assurance policy. Changes in availability, price, and market share were assessed against specified success benchmarks for 1 year of AMFm implementation. Key informant interviews and document reviews recorded contextual factors and the implementation process. In all pilots except Niger and Madagascar, there were large increases in QAACT availability (25·8-51·9 percentage points), and market share (15·9-40·3 percentage points), driven mainly by changes in the private for-profit sector. Large falls in median price for QAACTs per adult equivalent dose were seen in the private for-profit sector in six pilots, ranging from US$1·28 to $4·82. The market share of oral artemisinin monotherapies decreased in Nigeria and Zanzibar, the two pilots where it was more than 5% at baseline. Subsidies combined with supporting interventions can be effective in rapidly improving availability, price, and market share of QAACTs, particularly in the private for-profit sector. Decisions about the future of AMFm should also consider the effect on use in vulnerable populations, access to malaria diagnostics, and cost-effectiveness. The Global Fund to Fight AIDS, Tuberculosis and Malaria, and the Bill & Melinda Gates Foundation. Copyright © 2012 Elsevier Ltd. All rights reserved.

HCN channels segregate stimulation‐evoked movement responses in neocortex and allow for coordinated forelimb movements in rodents

PubMed Central

Farrell, Jordan S.; Palmer, Laura A.; Singleton, Anna C.; Pittman, Quentin J.; Teskey, G. Campbell

2016-01-01

Key points The present study tested whether HCN channels contribute to the organization of motor cortex and to skilled motor behaviour during a forelimb reaching task.Experimental reductions in HCN channel signalling increase the representation of complex multiple forelimb movements in motor cortex as assessed by intracortical microstimulation.Global HCN1KO mice exhibit reduced reaching accuracy and atypical movements during a single‐pellet reaching task relative to wild‐type controls.Acute pharmacological inhibition of HCN channels in forelimb motor cortex decreases reaching accuracy and increases atypical movements during forelimb reaching. Abstract The mechanisms by which distinct movements of a forelimb are generated from the same area of motor cortex have remained elusive. Here we examined a role for HCN channels, given their ability to alter synaptic integration, in the expression of forelimb movement responses during intracortical microstimulation (ICMS) and movements of the forelimb on a skilled reaching task. We used short‐duration high‐resolution ICMS to evoke forelimb movements following pharmacological (ZD7288), experimental (electrically induced cortical seizures) or genetic approaches that we confirmed with whole‐cell patch clamp to substantially reduce I h current. We observed significant increases in the number of multiple movement responses evoked at single sites in motor maps to all three experimental manipulations in rats or mice. Global HCN1 knockout mice were less successful and exhibited atypical movements on a skilled‐motor learning task relative to wild‐type controls. Furthermore, in reaching‐proficient rats, reaching accuracy was reduced and forelimb movements were altered during infusion of ZD7288 within motor cortex. Thus, HCN channels play a critical role in the separation of overlapping movement responses and allow for successful reaching behaviours. These data provide a novel mechanism for the encoding of multiple movement responses within shared networks of motor cortex. This mechanism supports a viewpoint of primary motor cortex as a site of dynamic integration for behavioural output. PMID:27568501

Data Rights and Responsibilities: A Human Rights Perspective on Data Sharing.

PubMed

Harris, Theresa L; Wyndham, Jessica M

2015-07-01

A human-rights-based analysis can be a useful tool for the scientific community and policy makers as they develop codes of conduct, harmonized standards, and national policies for data sharing. The human rights framework provides a shared set of values and norms across borders, defines rights and responsibilities of various actors involved in data sharing, addresses the potential harms as well as the benefits of data sharing, and offers a framework for balancing competing values. The right to enjoy the benefits of scientific progress and its applications offers a particularly helpful lens through which to view data as both a tool of scientific inquiry to which access is vital and as a product of science from which everyone should benefit. © The Author(s) 2015.

Measuring the relative resilience of subarctic lakes to global change: redundancies of functions within and across temporal scales

USGS Publications Warehouse

Angeler, David G.; Allen, Craig R.; Johnson, Richard K.

2013-01-01

1. Ecosystems at high altitudes and latitudes are expected to be particularly vulnerable to the effects of global change. We assessed the responses of littoral invertebrate communities to changing abiotic conditions in subarctic Swedish lakes with long-term data (1988–2010) and compared the responses of subarctic lakes with those of more southern, hemiboreal lakes. 2. We used a complex systems approach, based on multivariate time-series modelling, and identified dominant and distinct temporal frequencies in the data; that is, we tracked community change at distinct temporal scales. We determined the distribution of functional feeding groups of invertebrates within and across temporal scales. Within and cross-scale distributions of functions have been considered to confer resilience to ecosystems, despite changing environmental conditions. 3. Two patterns of temporal change within the invertebrate communities were identified that were consistent across the lakes. The first pattern was one of monotonic change associated with changing abiotic lake conditions. The second was one of showing fluctuation patterns largely unrelated to gradual environmental change. Thus, two dominant and distinct temporal frequencies (temporal scales) were present in all lakes analysed. 4. Although the contribution of individual feeding groups varied between subarctic and hemiboreal lakes, they shared overall similar functional attributes (richness, evenness, diversity) and redundancies of functions within and between the observed temporal scales. This highlights similar resilience characteristics in subarctic and hemiboreal lakes. 5. Synthesis and applications. The effects of global change can be particularly strong at a single scale in ecosystems. Over time, this can cause monotonic change in communities and eventually lead to a loss of important ecosystem services upon reaching a critical threshold. Dynamics at other spatial or temporal scales can be unrelated to environmental change. The relative ‘intactness’ of these scales that are unaffected by global change and the persistence of functions at those scales may safeguard the whole system from the potential loss of functions at the scale at which global change impacts can be substantial. Thus, an understanding of scale-specific processes provides managers with a realistic assessment of vulnerabilities and the relative resilience of ecosystems to environmental change. Explicit consideration of ‘intact’ and ‘affected’ scales in analyses of global change impacts provides opportunities to tailor more specific management plans.

Helping the Warfighter Become Green! (Briefing Charts)

DTIC Science & Technology

2011-02-01

CHAIN LEADERSHIPARFIGHTER-FOCUSED, GLOBALLY RESPONSIVE, FISCALLY RESPONSIBLE SUPPLY CHAIN LEADERSHIP DOD EMALL DOD’s Online Shopping Tool • Web self...LEADERSHIP DOD EMALL DOD’s Online Shopping Tool WARFIGHTER FOCUSED, GLOBALLY RESPONSIVE SUPPLY CHAIN LEADERSHIPARFIGHTER FOCUSED, GLOBALLY RESPONSIVE

Engineering Ethics Education Having Reflected Various Values and a Global Code of Ethics

NASA Astrophysics Data System (ADS)

Kanemitsu, Hidekazu

At the present day, a movement trying to establish a global code of ethics for science and engineering is in activity. The author overviews the context of this movement, and examines the possibility of engineering ethics education which uses global code of ethics. In this paper, the engineering ethics education which uses code of ethics in general will be considered, and an expected function of global code of ethics will be also. Engineering ethics education in the new century should be aimed to share the values among different countries and cultures. To use global code of ethics as a tool for such education, the code should include various values, especially Asian values which engineering ethics has paid little attention to.

Converging on child mental health - toward shared global action for child development.

PubMed

Belkin, G; Wissow, L; Lund, C; Aber, L; Bhutta, Z; Black, M; Kieling, C; McGregor, S; Rahman, A; Servili, C; Walker, S; Yoshikawa, H

2017-01-01

We are a group of researchers and clinicians with collective experience in child survival, nutrition, cognitive and social development, and treatment of common mental conditions. We join together to welcome an expanded definition of child development to guide global approaches to child health and overall social development. We call for resolve to integrate maternal and child mental health with child health, nutrition, and development services and policies, and see this as fundamental to the health and sustainable development of societies. We suggest specific steps toward achieving this objective, with associated global organizational and resource commitments. In particular, we call for a Global Planning Summit to establish a much needed Global Alliance for Child Development and Mental Health in all Policies.

Countering Strategic Preclusion: The Requirement for Truly Global Reach in the 21st Century

DTIC Science & Technology

2012-06-01

Website, http://www.618tacc. amc.af.mil/shared/ media /document/AFD-110602-022.pdf (accessed 24 May 2012). The inter-theater airlift support to Operation...Crisis,” Pacific Air Forces Official Website, http://www.pacaf. af.mil/shared/ media /document/AFD-110330-077.pdf [accessed 24 May 2012...Reconnaissance Office (NRO), which lists as one of its key functions providing targeting and BDA support to military operations. These are

U.S. Initiatives to Promote Global Internet Freedom: Issues, Policy, and Technology

DTIC Science & Technology

2010-03-17

video sharing sites, and other tools of today’s communications technology has proven to be an unprecedented and often disruptive force in some closed...using newer tools, such as blogs, social networks, video sharing sites, and other aspects of today’s communications technology to express their...Iranians sent VOA over 300 videos a day, along with thousands of still pictures, e-mails, and telephone calls to the agency.2 A variety of control

The Soil Moisture Active and Passive (SMAP) Mission

NASA Technical Reports Server (NTRS)

Entekhabi, Dara; Nijoku, Eni G.; ONeill, Peggy E.; Kellogg, Kent H.; Crow, Wade T.; Edelstein, Wendy N.; Entin, Jared K.; Goodman, Shawn D.; Jackson, Thomas J.; Johnson, Joel;

The provision of ecosystem services in response to global change: Evidences and applications.

PubMed

Lafortezza, Raffaele; Chen, Jiquan

2016-05-01

As a consequence of the global increase in economic and societal prosperity, ecosystems and natural resources have been substantially exploited, degraded, or even destroyed in the last century. To prevent further deprivation of the quality of ecosystems, the ecosystem services concept has become a central issue in environmental studies. A growing number of environmental agencies and organizations worldwide are now embracing integrated approaches to plan and manage ecosystems, sharing a goal to maintain the long-term provision of ecosystem services for sustainability. A daunting challenge in this process is to move from general pronouncements about the tremendous benefits that ecosystems provide to society to defensible assessments of their services. In other words, we must move beyond the scientific evidences of the ecosystem services concept to its practical applications. In this work, we discuss the theoretical foundations and applications of ecosystem services with a focus on the assessment of ecosystem service trade-offs and synergies at various spatial and temporal scales. Here, we offer examples of the main factors related to land use management that may affect the provision of ecosystem services and provide direction for future research on ecosystem services and related nature-based solutions. We also provide a briefing on the major topics covered in this Special Issue, which focuses on the provision of ecosystem services in the context of global change. Copyright © 2016 Elsevier Inc. All rights reserved.

Footprinting analysis of interactions between the largest eukaryotic RNase P/MRP protein Pop1 and RNase P/MRP RNA components.

PubMed

Fagerlund, Robert D; Perederina, Anna; Berezin, Igor; Krasilnikov, Andrey S

2015-09-01

Ribonuclease (RNase) P and RNase MRP are closely related catalytic ribonucleoproteins involved in the metabolism of a wide range of RNA molecules, including tRNA, rRNA, and some mRNAs. The catalytic RNA component of eukaryotic RNase P retains the core elements of the bacterial RNase P ribozyme; however, the peripheral RNA elements responsible for the stabilization of the global architecture are largely absent in the eukaryotic enzyme. At the same time, the protein makeup of eukaryotic RNase P is considerably more complex than that of the bacterial RNase P. RNase MRP, an essential and ubiquitous eukaryotic enzyme, has a structural organization resembling that of eukaryotic RNase P, and the two enzymes share most of their protein components. Here, we present the results of the analysis of interactions between the largest protein component of yeast RNases P/MRP, Pop1, and the RNA moieties of the enzymes, discuss structural implications of the results, and suggest that Pop1 plays the role of a scaffold for the stabilization of the global architecture of eukaryotic RNase P RNA, substituting for the network of RNA-RNA tertiary interactions that maintain the global RNA structure in bacterial RNase P. © 2015 Fagerlund et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Future air pollution in the Shared Socio-economic Pathways

DOE PAGES

Rao, Shilpa; Klimont, Zbigniew; Smith, Steven J.; ...

2016-07-15

Emissions of air pollutants such as sulfur and nitrogen oxides and particulates have significant health impacts as well as effects on natural and anthropogenic ecosystems. These same emissions also can change atmospheric chemistry and the planetary energy balance, thereby impacting global and regional climate. Long-term scenarios for air pollutant emissions are needed as inputs to global climate and chemistry models, and for analysis linking air pollutant impacts across sectors. In this paper we present methodology and results for air pollutant emissions in Shared Socioeconomic Pathways (SSP) scenarios. We first present a set of three air pollution narratives that describe high,more » central, and low pollution control ambitions over the 21 st century. These narratives are then translated into quantitative guidance for use in integrated assessment models. We provide an overview of pollutant emission trajectories under the SSP scenarios. Pollutant emissions in these scenarios cover a wider range than the scenarios used in previous international climate model comparisons. Furthermore, the SSP scenarios provide the opportunity to access a more comprehensive range of future global and regional air quality outcomes.« less

Future air pollution in the Shared Socio-economic Pathways

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rao, Shilpa; Klimont, Zbigniew; Smith, Steven J.

Emissions of air pollutants such as sulfur and nitrogen oxides and particulates have significant health impacts as well as effects on natural and anthropogenic ecosystems. These same emissions also can change atmospheric chemistry and the planetary energy balance, thereby impacting global and regional climate. Long-term scenarios for air pollutant emissions are needed as inputs to global climate and chemistry models, and for analysis linking air pollutant impacts across sectors. In this paper we present methodology and results for air pollutant emissions in Shared Socioeconomic Pathways (SSP) scenarios. We first present a set of three air pollution narratives that describe high,more » central, and low pollution control ambitions over the 21 st century. These narratives are then translated into quantitative guidance for use in integrated assessment models. We provide an overview of pollutant emission trajectories under the SSP scenarios. Pollutant emissions in these scenarios cover a wider range than the scenarios used in previous international climate model comparisons. Furthermore, the SSP scenarios provide the opportunity to access a more comprehensive range of future global and regional air quality outcomes.« less

Extracting the Evaluations of Stereotypes: Bi-factor Model of the Stereotype Content Structure

PubMed Central

Sayans-Jiménez, Pablo; Cuadrado, Isabel; Rojas, Antonio J.; Barrada, Juan R.

2017-01-01

Stereotype dimensions—competence, morality and sociability—are fundamental to studying the perception of other groups. These dimensions have shown moderate/high positive correlations with each other that do not reflect the theoretical expectations. The explanation for this (e.g., halo effect) undervalues the utility of the shared variance identified. In contrast, in this work we propose that this common variance could represent the global evaluation of the perceived group. Bi-factor models are proposed to improve the internal structure and to take advantage of the information representing the shared variance among dimensions. Bi-factor models were compared with first order models and other alternative models in three large samples (300–309 participants). The relationships among the global and specific bi-factor dimensions with a global evaluation dimension (measured through a semantic differential) were estimated. The results support the use of bi-factor models rather than first order models (and other alternative models). Bi-factor models also show a greater utility to directly and more easily explore the stereotype content including its evaluative content. PMID:29085313

Policy enabled information sharing system

DOEpatents

Jorgensen, Craig R.; Nelson, Brian D.; Ratheal, Steve W.

2014-09-02

A technique for dynamically sharing information includes executing a sharing policy indicating when to share a data object responsive to the occurrence of an event. The data object is created by formatting a data file to be shared with a receiving entity. The data object includes a file data portion and a sharing metadata portion. The data object is encrypted and then automatically transmitted to the receiving entity upon occurrence of the event. The sharing metadata portion includes metadata characterizing the data file and referenced in connection with the sharing policy to determine when to automatically transmit the data object to the receiving entity.

Job Sharing for Administrators: A Consideration for Public Schools.

ERIC Educational Resources Information Center

Muffs, Michael I.; Schmitz, Laura Ann

1999-01-01

To retain an exemplary dean of students with heavy caregiving responsibilities, a Poughkeepsie, New York, high school adopted a plan to split her job responsibilities with an educational administration student beginning his career. Job-sharing success hinged on strong cooperation among the district, the individual administrators, and local…

Understanding and Dismantling Barriers for Partnerships for Inclusive Education: A Cultural Historical Activity Theory Perspective

ERIC Educational Resources Information Center

Waitoller, Federico R.; Kozleski, Elizabeth B.

2013-01-01

Increasingly, universities and school districts share responsibility for teacher and student learning. Sharing responsibility demands that both institutions work to develop closer relationships through ongoing engagement, dialogue and negotiation. Drawing from Cultural Historical Activity Theory (CHAT), we examined one school/university…

Sharing Leadership Responsibilities Results in Achievement Gains

ERIC Educational Resources Information Center

Armistead, Lew

2010-01-01

Collective, not individual, leadership in schools has a greater impact on student achievement; when principals and teachers share leadership responsibilities, student achievement is higher; and schools having high student achievement also display a vision for student achievement and teacher growth. Those are just a few of the insights into school…

Cholera Prevention and Control

MedlinePlus

... name=”commit” type=”submit” value=”Submit” /> Prevention & Control Recommend on Facebook Tweet Share Compartir Prevention of ... of cholera and other diarrheal disease prevention. Prevention & Control Topics Ending Cholera: The Global Roadmap to 2030 ...

Methods and apparatuses for information analysis on shared and distributed computing systems

DOEpatents

Bohn, Shawn J [Richland, WA; Krishnan, Manoj Kumar [Richland, WA; Cowley, Wendy E [Richland, WA; Nieplocha, Jarek [Richland, WA

2011-02-22

Apparatuses and computer-implemented methods for analyzing, on shared and distributed computing systems, information comprising one or more documents are disclosed according to some aspects. In one embodiment, information analysis can comprise distributing one or more distinct sets of documents among each of a plurality of processes, wherein each process performs operations on a distinct set of documents substantially in parallel with other processes. Operations by each process can further comprise computing term statistics for terms contained in each distinct set of documents, thereby generating a local set of term statistics for each distinct set of documents. Still further, operations by each process can comprise contributing the local sets of term statistics to a global set of term statistics, and participating in generating a major term set from an assigned portion of a global vocabulary.

Accumulating Evidence for the Association and Shared Pathogenic Mechanisms between Psoriasis and Cardiovascular–Related Co-morbidities

PubMed Central

Shlyankevich, Julia; Mehta, Nehal N.; Krueger, James G.; Strober, Bruce; Gudjonsson, Johann E.; Qureshi, Abrar A.; Tebbey, Paul W.; Kimball, Alexandra Boer

2014-01-01

The International Psoriasis Council (IPC), a global non-profit organization dedicated to advancing psoriasis research and treatment, led an initiative to better define the association of various cardiometabolic comorbidities with psoriasis. In November 2013, a workshop was held in Boston, MA. By assembling a panel of global dermatology, immunology and cardiovascular experts, the objective was to better define the current status of the science that explains the association of psoriasis with various cardiometabolic-related comorbidities. IPC has played a historical role in associating psoriasis with various comorbidities by integrating multidisciplinary expertise to advance the scientific and clinical knowledge through publications and clinical trials. This report synthesizes the current understanding of psoriasis with various cardiometabolic risk factors by exploring the potential shared pathogenic mechanisms and genetic connectivity. PMID:25149424

A global water scarcity assessment under Shared Socio-economic Pathways - Part 1: Water use

NASA Astrophysics Data System (ADS)

Hanasaki, N.; Fujimori, S.; Yamamoto, T.; Yoshikawa, S.; Masaki, Y.; Hijioka, Y.; Kainuma, M.; Kanamori, Y.; Masui, T.; Takahashi, K.; Kanae, S.

2013-07-01

A novel global water scarcity assessment for the 21st century is presented in a two-part paper. In this first paper, water use scenarios are presented for the latest global hydrological models. The scenarios are compatible with the socio-economic scenarios of the Shared Socio-economic Pathways (SSPs), which are a part of the latest set of scenarios on global change developed by the integrated assessment, the IAV (climate change impact, adaptation, and vulnerability assessment), and the climate modeling community. The SSPs depict five global situations based on substantially different socio-economic conditions during the 21st century. Water use scenarios were developed to reflect not only quantitative socio-economic factors, such as population and electricity production, but also key qualitative concepts such as the degree of technological change and overall environmental consciousness. Each scenario consists of five factors: irrigated area, crop intensity, irrigation efficiency, and withdrawal-based potential industrial and municipal water demands. The first three factors are used to estimate the potential irrigation water demand. All factors were developed using simple models based on a literature review and analysis of historical records. The factors are grid-based at a spatial resolution of 0.5° × 0.5° and cover the whole 21st century in five-year intervals. Each factor shows wide variation among the different global situations depicted: the irrigated area in 2085 varies between 2.7 × 106 and 4.5 × 106 km2, withdrawal-based potential industrial water demand between 246 and 1714 km3 yr-1, and municipal water between 573 and 1280 km3 yr-1. The water use scenarios can be used for global water scarcity assessments that identify the regions vulnerable to water scarcity and analyze the timing and magnitude of scarcity conditions.

Rethinking Teacher Education: Synchronizing Eastern and Western Views of Teaching and Learning to Promote 21st Century Skills and Global Perspectives

ERIC Educational Resources Information Center

Smith, Judith; Hu, Ran

2013-01-01

The purpose of the study was to share findings with educators across disciplines of how to incorporate an eastern and western blended philosophy of teaching and learning to promote 21st century skills and global perspectives. Drawing from a previous self-study of their views of teaching and learning between Chinese and American cultures, the two…

MNE7 Access to the Global Commons Outcome 3 Cyber Domain. Objective 3.5 Cyber Situational Awareness. Concept of Employment for Cyber Situational Awareness Within the Global Commons Version 1.0

DTIC Science & Technology

2013-02-25

such as authentication , protocols, and ‘signature’ management exist but the imposition of such techniques must be balan 15p the legal requirements...gulation, mation face onflicting pressures to keep this data secure and yet allow access by authorised users. in the sharing network should be

Deriving a Campaign Plan for the Global Commons

DTIC Science & Technology

2011-08-13

insisted on the carriage of government observers on board tourist vessels entering the Ross Sea region, ostensibly to monitor tourist behavior in World...capability to exert control or enforce a sovereignty claim. However claims to the global commons and their governing regimes are not immutable. On the...characteristics such domains share: (1) each are governed by international treaties; (2) these treaties address specific permissible uses and prohibitions; (3

Water within the Shared Socioeconomic Pathways: Constraints and the Impact on Future Global Change Scenarios

NASA Astrophysics Data System (ADS)

Graham, N. T.; Hejazi, M. I.; Davies, E. G.; Calvin, K. V.; Kim, S. H.; Miralles-Wilhelm, F.

2017-12-01

The Shared Socioeconomic Pathways (SSPs) represent the next generation of future global change scenarios and their inclusion in the Coupled Model Intercomparison Project Phase 6 (CMIP6) scenarios reinforces the importance of a complete understanding of the SSPs. This study uses the Global Change Assessment Model (GCAM) to investigate the effects of limited water supplies on future withdrawals at regional and water basin scales across all SSPs in combination with various climate mitigation scenarios. Water supply is calculated using a global hydrologic model and water data from five ISI-MIP models across the four RCP scenarios. When water constraints are incorporated, our results show that water withdrawals are reduced by as much as 40% across all SSP scenarios without climate policies. As climate policies are imposed and become more stringent, water withdrawals increase in regions already affected by water stress in order to allow for greater biomass production. The results of this research show the importance of including water resource constraints within the SSP scenarios for establishing water withdrawal scenarios under a wide range of scenarios including different climate policies. The results will also provide data products - such as gridded land use and water demand estimates - of potential interest to the impact, adaptation, and vulnerability community following the SSP scenarios.

Supporting Effective Data Sharing and Re-Use: What Can Funders Really Do?

NASA Astrophysics Data System (ADS)

Uhle, M. E.

2017-12-01

Most research funding agencies have data policies that grantees must abide to receive financial support for projects and activities. These policies however are typically not uniform, can be inconsistent and in some cases, can be contradictory preventing national and international collaboration. In addition, disciplinary divisions within a single agency may implement agency policy differently. These barriers are particularly profound for multi, inter- and/or transdisciplinary research needed to address many global environmental challenges. Recognizing the crucial role of open and effective data and information exchange to support effective international transdisciplinary research for understanding, mitigating and adapting to global environmental change, the Belmont Forum adopted Open Data Policy and Principles in 2015. This policy signals a commitment by these 25 funders to increase access to scientific data, a step widely recognized as essential to making informed decisions in the face of rapid changes affecting the Earth's environment. Through collaborative research actions and community driven activities, the Belmont Forum seeks to widen access to data, and promote its long-term preservation in global change research; encourage re-use of existing data; help improve data management and exploitation; coordinate and integrate disparate organizational and technical elements; fill critical global e-infrastructure gaps; share best practices; and foster new data literacy.

Global socioeconomic carbon stocks in long-lived products 1900-2008

NASA Astrophysics Data System (ADS)

Lauk, Christian; Haberl, Helmut; Erb, Karl-Heinz; Gingrich, Simone; Krausmann, Fridolin

2012-09-01

A better understanding of the global carbon cycle as well as of climate change mitigation options such as carbon sequestration requires the quantification of natural and socioeconomic stocks and flows of carbon. A so-far under-researched aspect of the global carbon budget is the accumulation of carbon in long-lived products such as buildings and furniture. We present a comprehensive assessment of global socioeconomic carbon stocks and the corresponding in- and outflows during the period 1900-2008. These data allowed calculation of the annual carbon sink in socioeconomic stocks during this period. The study covers the most important socioeconomic carbon fractions, i.e. wood, bitumen, plastic and cereals. Our assessment was mainly based on production and consumption data for plastic, bitumen and wood products and the respective fractions remaining in stocks in any given year. Global socioeconomic carbon stocks were 2.3 GtC in 1900 and increased to 11.5 GtC in 2008. The share of wood in total C stocks fell from 97% in 1900 to 60% in 2008, while the shares of plastic and bitumen increased to 16% and 22%, respectively. The rate of gross carbon sequestration in socioeconomic stocks increased from 17 MtC yr-1 in 1900 to a maximum of 247 MtC yr-1 in 2007, corresponding to 2.2%-3.4% of global fossil-fuel-related carbon emissions. We conclude that while socioeconomic carbon stocks are not negligible, their growth over time is not a major climate change mitigation option and there is an only modest potential to mitigate climate change by the increase of socioeconomic carbon stocks.

Phylogenetic Analysis of the Spike (S) Gene of the New Variants of Porcine Epidemic Diarrhoea Virus in Taiwan.

PubMed

Chiou, H-Y; Huang, Y-L; Deng, M-C; Chang, C-Y; Jeng, C-R; Tsai, P-S; Yang, C; Pang, V F; Chang, H-W

2017-02-01

New variants of porcine epidemic diarrhoea virus (PEDV), which emerged in Taiwan in late 2013, have caused a high morbidity and mortality in neonatal piglets. To investigate the molecular characteristics of the spike (S) gene of the emerging Taiwan PEDV strains for a better understanding of the genetic diversity and relationship among the Taiwan new variants and the global PEDVs, full-length S genes of PEDVs from nine 1-7 day-old piglets from three pig farms in the central and southern Taiwan were sequenced and analysed. The result of phylogenetic analysis of the S gene showed that all the Taiwan PEDV strains were closely related to the non-S INDEL strains from US, Canada and China, suggesting a common ancestor for these strains. As compared with the historic PEDVs and CV777-based vaccine strains, the nine Taiwan PEDV variants shared almost the same genetic signatures as the global non-S INDEL strains, including a series of insertions, deletions and mutations in the amino terminal as well as identical mutations in the neutralizing epitopes of the S gene. The high similarity of the S protein among the Taiwan and the globally emerged non-S INDEL PEDV strains suggests that the Taiwan new variants may share similar pathogenesis and immunogenicity as the global outbreak variants. The development of a novel vaccine based on the Taiwan or the global non-S INDEL strains may be contributive to the control of the current global porcine epidemic diarrhoea outbreaks. © 2015 Blackwell Verlag GmbH.

Human resource constraints and the prospect of task-sharing among community health workers for the detection of early signs of pre-eclampsia in Ogun State, Nigeria.

PubMed

Akeju, David O; Vidler, Marianne; Sotunsa, J O; Osiberu, M O; Orenuga, E O; Oladapo, Olufemi T; Adepoju, A A; Qureshi, Rahat; Sawchuck, Diane; Adetoro, Olalekan O; von Dadelszen, Peter; Dada, Olukayode A

2016-09-30

The dearth of health personnel in low income countries has attracted global attention. Ways as to how health care services can be delivered in a more efficient and effective way using available health personnel are being explored. Task-sharing expands the responsibilities of low-cadre health workers and allows them to share these responsibilities with highly qualified health care providers in an effort to best utilize available human resources. This is appropriate in a country like Nigeria where there is a shortage of qualified health professionals and a huge burden of maternal mortality resulting from obstetric complications like pre-eclampsia. This study examines the prospect for task-sharing among Community Health Extension Workers (CHEW) for the detection of early signs of pre-eclampsia, in Ogun State, Nigeria. This study is part of a larger community-based trial evaluating the acceptability of community treatment for severe pre-eclampsia in Ogun State, Nigeria. Data was collected between 2011 and 2012 using focus group discussions; seven with CHEWs (n = 71), three with male decision-makers (n = 35), six with community leaders (n = 68), and one with member of the Society of Obstetricians and Gynaecologists of Nigeria (n = 9). In addition, interviews were conducted with the heads of the local government administration (n = 4), directors of planning (n = 4), medical officers (n = 4), and Chief Nursing Officers (n = 4). Qualitative data were analysed using NVivo version 10.0 3 computer software. The non-availability of health personnel is a major challenge, and has resulted in a high proportion of facility-based care performed by CHEWs. As a result, CHEWs often take on roles that are designated for senior health workers. This role expansion has exposed CHEWs to the basics of obstetric care, and has resulted in informal task-sharing among the health workers. The knowledge and ability of CHEWs to perform basic clinical assessments, such as measure blood pressure is not in doubt. Nevertheless, there were divergent views by senior and junior cadres of health practitioners about CHEWs' abilities in providing obstetric care. Similarly, there were concerns by various stakeholders, particularly the CHEWs themselves, on the regulatory restrictions placed on them by the Standing Order. Generally, the extent to which obstetric tasks could be shifted to community health workers will be determined by the training provided and the extent to which the observed barriers are addressed. NCT01911494.

Managing differences: the central challenge of global strategy.

PubMed

Ghemawat, Pankaj

2007-03-01

The main goal of any international strategy should be to manage the large differences that arise at the borders of markets. Yet executives often fail to exploit market and production discrepancies, focusing instead on the tensions between standardization and localization. In this article, Pankaj Ghemawat presents a new framework that encompasses all three effective responses to the challenges of globalization. He calls it the AAA Triangle. The A's stand for the three distinct types of international strategy. Through adaptation, companies seek to boost revenues and market share by maximizing their local relevance. Through aggregation, they attempt to deliver economies of scale by creating regional, or sometimes global, operations. And through arbitrage, they exploit disparities between national or regional markets, often by locating different parts of the supply chain in different places--for instance, call centers in India, factories in China, and retail shops in Western Europe. Ghemawat draws on several examples that illustrate how organizations use and balance these strategies and describes the trade-offs they make as they do so. Because most enterprises should draw from all three A's to some extent, the framework can be used to develop a summary scorecard indicating how well the company is globalizing. However, given the tensions among the strategies, it's not enough simply to tick off the corresponding boxes. Strategic choice requires some degree of prioritization--and the framework can help with that as well. While it is possible to make progress on all three strategies, companies usually must focus on one or two when trying to build competitive advantage.

Data Rights and Responsibilities

PubMed Central

Wyndham, Jessica M.

2015-01-01

A human-rights-based analysis can be a useful tool for the scientific community and policy makers as they develop codes of conduct, harmonized standards, and national policies for data sharing. The human rights framework provides a shared set of values and norms across borders, defines rights and responsibilities of various actors involved in data sharing, addresses the potential harms as well as the benefits of data sharing, and offers a framework for balancing competing values. The right to enjoy the benefits of scientific progress and its applications offers a particularly helpful lens through which to view data as both a tool of scientific inquiry to which access is vital and as a product of science from which everyone should benefit. PMID:26297755

10 rules for managing global innovation.

PubMed

Wilson, Keeley; Doz, Yves L

2012-10-01

More and more companies recognize that their dispersed, global operations are a treasure trove of ideas and capabilities for innovation. But it's proving harder than expected to unearth those ideas or exploit those capabilities. Part of the problem is that companies manage global innovation the same way they manage traditional, single-location projects. Single-location projects draw on a large reservoir of tacit knowledge, shared context, and trust that global projects lack. The management challenge, therefore, is to replicate the positive aspects of colocation while harnessing the opportunities of dispersion. In this article, Insead's Wilson and Doz draw on research into global strategy and innovation to present a set of guidelines for setting up and managing global innovation. They explore in detail the challenges that make global projects inherently different and show how these can be overcome by applying superior project management skills across teams, fostering a strong collaborative culture, and using a robust array of communications tools.

Do intraspecific or interspecific interactions determine responses to predators feeding on a shared size-structured prey community?

PubMed

ten Brink, Hanna; Mazumdar, Abul Kalam Azad; Huddart, Joseph; Persson, Lennart; Cameron, Tom C

2015-03-01

Coexistence of predators that share the same prey is common. This is still the case in size-structured predator communities where predators consume prey species of different sizes (interspecific prey responses) or consume different size classes of the same species of prey (intraspecific prey responses). A mechanism has recently been proposed to explain coexistence between predators that differ in size but share the same prey species, emergent facilitation, which is dependent on strong intraspecific responses from one or more prey species. Under emergent facilitation, predators can depend on each other for invasion, persistence or success in a size-structured prey community. Experimental evidence for intraspecific size-structured responses in prey populations remains rare, and further questions remain about direct interactions between predators that could prevent or limit any positive effects between predators [e.g. intraguild predation (IGP)]. Here, we provide a community-wide experiment on emergent facilitation including natural predators. We investigate both the direct interactions between two predators that differ in body size (fish vs. invertebrate predator), and the indirect interaction between them via their shared prey community (zooplankton). Our evidence supports the most likely expectation of interactions between differently sized predators that IGP rates are high, and interspecific interactions in the shared prey community dominate the response to predation (i.e. predator-mediated competition). The question of whether emergent facilitation occurs frequently in nature requires more empirical and theoretical attention, specifically to address the likelihood that its pre-conditions may co-occur with high rates of IGP. © 2014 The Authors. Journal of Animal Ecology © 2014 British Ecological Society.

Inside the black box of shared decision making: distinguishing between the process of involvement and who makes the decision

PubMed Central

Edwards, Adrian; Elwyn, Glyn

2006-01-01

Abstract Background  Shared decision making has practical implications for everyday health care. However, it stems from largely theoretical frameworks and is not widely implemented in routine practice. Aims  We undertook an empirical study to inform understanding of shared decision making and how it can be operationalized more widely. Method  The study involved patients visiting UK general practitioners already well experienced in shared decision making. After these consultations, semi‐structured telephone interviews were conducted and analysed using the constant comparative method of content analysis. Results  All patients described at least some components of shared decision making but half appeared to perceive the decision as shared and half as ‘patient‐led’. However, patients exhibited some uncertainty about who had made the decision, reflecting different meanings of decision making from those described in the literature. A distinction is indicated between the process of involvement (option portrayal, exchange of information and exploring preferences for who makes the decision) and the actual decisional responsibility (who makes the decision). The process of involvement appeared to deliver benefits for patients, not the action of making the decision. Preferences for decisional responsibility varied during some consultations, generating unsatisfactory interactions when actual decisional responsibility did not align with patient preferences at that stage of a consultation. However, when conducted well, shared decision making enhanced reported satisfaction, understanding and confidence in the decisions. Conclusions  Practitioners can focus more on the process of involving patients in decision making rather than attaching importance to who actually makes the decision. They also need to be aware of the potential for changing patient preferences for decisional responsibility during a consultation and address non‐alignment of patient preferences with the actual model of decision making if this occurs. PMID:17083558

DoD Global Emerging Infections Surveillance & Response System (DoD-GEIS). Global Influenza Surveillance Efforts

DTIC Science & Technology

2007-01-08

DoD Global Emerging Infections Surveillance & Response System (DoD-GEIS) Global Influenza Surveillance Efforts 8 January 2007 COL (Ret.) Jose L...SUBTITLE DoD Global Emerging Infections Surveillance & Response System (DoD-GEIS) Global Influenza Surveillance Efforts 5a. CONTRACT NUMBER 5b. GRANT...PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Lab-Based Influenza Surveillance • Sentinel Surveillance • Air Force

Financing national non-communicable disease responses.

PubMed

Allen, Luke Nelson

2017-01-01

Non-communicable diseases (NCDs) (also known as socially transmitted diseases) were conspicuously absent from the Millennium Development Goals and seemed to miss out on the 'golden years' of health funding despite causing more death and disability than any other disease group worldwide. The share of 'development assistance for health' dedicated to NCDs has remained at 1-2% of the total since 2000. This level of funding is insufficient to attain the nine targets in the World Health Organization (WHO) Global Action Plan on NCDs. In 2015 the Sustainable Development Goals - which include the target of reducing premature NCD mortality by a third - were endorsed by 193 countries. Whilst this commitment is welcome, the same text stresses the primacy of domestic financing, which is currently dominated by out-of-pocket payments in low- and middle-income countries (LMICs). This paper presents the findings of the WHO Global Coordination Mechanism on NCDs financing working group. The group was convened to explore NCD financing options with an emphasis on LMICs. The main sources of available finance include taxation, loans, engagement with the private sector, impact investment and innovative financing mechanisms. There is a role for development assistance to increase in the interim as raising additional revenue from these sources will take time. In the medium term it may be appropriate for international NCD funding to remain low where LMICs successfully assume financial responsibility for preventing and controlling NCDs. Countries will have to manage blends of innovative and traditional funding sources, whilst finding ways to boost tax revenue for NCDs.

Global commitments and China's endeavors to promote health and achieve sustainable development goals.

PubMed

Tan, Xiaodong; Wu, Qian; Shao, Haiyan

2018-04-12

With its immense population and as the largest developing country in the world, China has made remarkable achievements in health promotion at a relatively low cost. However, China is still faced with challenges such as changes of disease spectrum, the coming era of an aging society, and the risk of environmental pollution. On October 25, 2016, China formally passed the blueprint of "Healthy China 2030," working towards the national goal of reaching a health standard on par with developed countries by 2030, which was also a response to realize the 2030 United Nations Sustainable Development Goals. "Healthy China 2030" is comprised of 29 chapters that cover five health areas. China is sparing no effort to transfer from being merely the most populous country, to becoming a leading nation in health education. In "Healthy China 2030," collaborated construction and resource sharing were clearly stated as the core strategy. A shift in concentration towards coordinated development of health-based economy from a previous pursuit of rapid economic growth was also underlined. There are also several major issues, such as severely aging population, the burden of chronic diseases, the insufficiency of health expenditure, and the great demand on health protection, waiting to be dealt with during the implementation process of "Healthy China 2030". "Healthy China 2030" is a momentous move to enhance public health, which is also a response to the global commitments. We also need to rethink our approach to reach the living standards and maintain a better environment.

Response of the tropical Pacific Ocean to El Niño versus global warming

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Fukai; Luo, Yiyong; Lu, Jian

Climate models project an El Niño-like SST response in the tropical Pacific Ocean to global warming (GW). By employing the Community Earth System Model (CESM) and applying an overriding technique to its ocean component, Parallel Ocean Program version 2 (POP2), this study investigates the similarity and difference of formation mechanism for the changes in the tropical Pacific Ocean under El Niño and GW. Results show that, despite sharing some similarities between the two scenarios, there are many significant distinctions between GW and El Niño: 1) the phase locking of the seasonal cycle reduction is more notable under GW compared withmore » El Niño, implying more extreme El Niño events in the future; 2) in contrast to the penetration of the equatorial subsurface temperature anomaly that appears to propagate in the form of an oceanic equatorial upwelling Kelvin wave during El Niño, the GW-induced subsurface temperature anomaly manifest in the form of off-equatorial upwelling Rossby waves; 3) while significant across-equator northward heat transport (NHT) is induced by the wind stress anomalies associated with El Niño, little NHT is found at the equator due to a symmetric change in the shallow meridional overturning circulation that appears to be weakened in both North and South Pacific under GW; and 4) the maintaining mechanisms for the eastern equatorial Pacific warming are also substantially different.« less

A case-based, problem-based learning approach to prepare master of public health candidates for the complexities of global health.

PubMed

Leon, Juan S; Winskell, Kate; McFarland, Deborah A; del Rio, Carlos

2015-03-01

Global health is a dynamic, emerging, and interdisciplinary field. To address current and emerging global health challenges, we need a public health workforce with adaptable and collaborative problem-solving skills. In the 2013-2014 academic year, the Hubert Department of Global Health at the Rollins School of Public Health-Emory University launched an innovative required core course for its first-year Master of Public Health students in the global health track. The course uses a case-based, problem-based learning approach to develop global health competencies. Small teams of students propose solutions to these problems by identifying learning issues and critically analyzing and synthesizing new information. We describe the course structure and logistics used to apply this approach in the context of a large class and share lessons learned.

Exploratory Investigation of Bacteroides fragilis Transcriptional Response during In vitro Exposure to Subinhibitory Concentration of Metronidazole.

PubMed

de Freitas, Michele C R; Resende, Juliana A; Ferreira-Machado, Alessandra B; Saji, Guadalupe D R Q; de Vasconcelos, Ana T R; da Silva, Vânia L; Nicolás, Marisa F; Diniz, Cláudio G

2016-01-01

Bacteroides fragilis , member from commensal gut microbiota, is an important pathogen associated to endogenous infections and metronidazole remains a valuable antibiotic for the treatment of these infections, although bacterial resistance is widely reported. Considering the need of a better understanding on the global mechanisms by which B. fragilis survive upon metronidazole exposure, we performed a RNA-seq transcriptomic approach with validation of gene expression results by qPCR. Bacteria strains were selected after in vitro subcultures with subinhibitory concentration (SIC) of the drug. From a wild type B. fragilis ATCC 43859 four derivative strains were selected: first and fourth subcultures under metronidazole exposure and first and fourth subcultures after drug removal. According to global gene expression analysis, 2,146 protein coding genes were identified, of which a total of 1,618 (77%) were assigned to a Gene Ontology term (GO), indicating that most known cellular functions were taken. Among these 2,146 protein coding genes, 377 were shared among all strains, suggesting that they are critical for B. fragilis survival. In order to identify distinct expression patterns, we also performed a K-means clustering analysis set to 15 groups. This analysis allowed us to detect the major activated or repressed genes encoding for enzymes which act in several metabolic pathways involved in metronidazole response such as drug activation, defense mechanisms against superoxide ions, high expression level of multidrug efflux pumps, and DNA repair. The strains collected after metronidazole removal were functionally more similar to those cultured under drug pressure, reinforcing that drug-exposure lead to drastic persistent changes in the B. fragilis gene expression patterns. These results may help to elucidate B. fragilis response during metronidazole exposure, mainly at SIC, contributing with information about bacterial survival strategies under stress conditions in their environment.

The role of home literacy practices in preschool children's language and emergent literacy skills.

PubMed

Roberts, Joanne; Jurgens, Julia; Burchinal, Margaret

2005-04-01

This study examined how 4 specific measures of home literacy practices (i.e., shared book reading frequency, maternal book reading strategies, child's enjoyment of reading, and maternal sensitivity) and a global measure of the quality and responsiveness of the home environment during the preschool years predicted children's language and emergent literacy skills between the ages of 3 and 5 years. Study participants were 72 African American children and their mothers or primary guardians primarily from low-income families whose home literacy environment and development have been followed since infancy. Annually, between 18 months and 5 years of age, the children's mothers were interviewed about the frequency they read to their child and how much their child enjoyed being read to, and the overall quality and responsiveness of the home environment were observed. Mothers also were observed reading to their child once a year at 2, 3, and 4 years of age, and maternal sensitivity and types of maternal book reading strategies were coded. Children's receptive and expressive language and vocabulary were assessed annually between 3 years of age and kindergarten entry, and emergent literacy skills were assessed at 4 years and kindergarten entry. The specific home literacy practices showed moderate to large correlations with each other, and only a few significant associations with the language and literacy outcomes, after controlling for maternal education, maternal reading skills, and the child's gender. The global measure of overall responsiveness and support of the home environment was the strongest predictor of children's language and early literacy skills and contributed over and above the specific literacy practice measures in predicting children's early language and literacy development.

Keeping the Whole Village Together: Sharing Responsibility for the Learning of All Students.

ERIC Educational Resources Information Center

Pacheco, Arturo; Brady, Tom; Blake, Sally; Della-Piana, Connie Kubo

This paper explains that to educate all students is the shared responsibility of partnerships within higher education and between higher education and the schools. The Partnership for Excellence in Teacher Education (PETE) incorporates this "whole village" approach into the design and implementation of school-based science and…

Children's and Adolescents' Decisions about Sharing Money with Others

ERIC Educational Resources Information Center

Leman, Patrick J.; Keller, Monika; Takezawa, Masanori; Gummerum, Michaela

2009-01-01

Two hundred and ninety-four participants aged between 7 and 17 years of age were asked to share out money between themselves and another, imaginary group. Individual responses were recorded as well as responses after discussion in a group with two other participants. The distribution task took place in two different experimental conditions that…

Shared Responsibility and Issues of Injustice and Harm within Sport

ERIC Educational Resources Information Center

Sartore-Baldwin, Melanie L.; McCullough, Brian; Quatman-Yates, Catherine

2017-01-01

The purpose of this article is to present a conceptual model of shared responsibility within the sport context. Focusing on issues of harm and injustice, this model proposes that organized sport can exist as an oppressive social structure that endorses ignorance through the presence of asymmetrical power relations. This ignorance reinforces…

78 FR 19155 - Shared Responsibility Payment for Not Maintaining Minimum Essential Coverage

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 [REG-148500-12] RIN 1545-BL36 Shared Responsibility Payment for Not Maintaining Minimum Essential Coverage Correction In proposed rule document 2013-2141 appearing on pages 7314-7331 in the issue of Monday, February 1, 2013, make the...