Single crystalline electronic structure and growth mechanism of aligned square graphene sheets

NASA Astrophysics Data System (ADS)

Yang, H. F.; Chen, C.; Wang, H.; Liu, Z. K.; Zhang, T.; Peng, H.; Schröter, N. B. M.; Ekahana, S. A.; Jiang, J.; Yang, L. X.; Kandyba, V.; Barinov, A.; Chen, C. Y.; Avila, J.; Asensio, M. C.; Peng, H. L.; Liu, Z. F.; Chen, Y. L.

2018-03-01

Recently, commercially available copper foil has become an efficient and inexpensive catalytic substrate for scalable growth of large-area graphene films for fundamental research and applications. Interestingly, despite its hexagonal honeycomb lattice, graphene can be grown into large aligned square-shaped sheets on copper foils. Here, by applying angle-resolved photoemission spectroscopy with submicron spatial resolution (micro-ARPES) to study the three-dimensional electronic structures of square graphene sheets grown on copper foils, we verified the high quality of individual square graphene sheets as well as their merged regions (with aligned orientation). Furthermore, by simultaneously measuring the graphene sheets and their substrate copper foil, we not only established the (001) copper surface structure but also discovered that the square graphene sheets' sides align with the ⟨110⟩ copper direction, suggesting an important role of copper substrate in the growth of square graphene sheets—which will help the development of effective methods to synthesize high-quality large-size regularly shaped graphene sheets for future applications. This work also demonstrates the effectiveness of micro-ARPES in exploring low-dimensional materials down to atomic thickness and sub-micron lateral size (e.g., besides graphene, it can also be applied to transition metal dichalcogenides and various van der Waals heterostructures)

Stress studies in EFG

NASA Technical Reports Server (NTRS)

1982-01-01

A program to study stress generation mechanisms in silicon sheet growth was started. The purpose of the research is to define post-growth temperature profiles for the sheet that can minimize its stress during growth at high speeds, e.g., greater than 3 cm/min. The initial tasks described concern work in progress toward the development of computing capabilities to (1) model stress-temperature relationships in steady-state ribbon growth, and (2) provide a means to calculate realistic temperature fields in ribbon, given growth system component temperatures as boundary conditions. If it is determined that low stress configurations can be achieved, the modeling is to be tested experimentally by constructing low-stress growth systems for EFG silicon ribbon.

A new approach to the linear theory of single-species tearing in two-dimensional quasi-neutral sheets

NASA Technical Reports Server (NTRS)

Brittnacher, M.; Quest, K. B.; Karimabadi, H.

1995-01-01

We have developed the linear theory of collisionless ion tearing in a two-dimensional magnetotail equilibrium for a single resonant species. We have solved the normal mode problem for tearing instability by an algorithm that employs particle-in-cell simulation to calculate the orbit integrals in the Maxwell-Vlasov eigenmode equation. The results of our single-species tearing analysis can be applied to ion tearing where electron effects are not included. We have calculated the tearing growth rate as a function of the magnetic field component B(sub n) normal to the current sheet for thick and thin current sheets, and we show that marginal stability occurs when the normal gyrofrequency Omega(sub n) is comparable to the Harris neutral sheet growth rate. A cross-tail B(sub y) component has little effect on the growth rate for B(sub y) approximately = B(sub n). Even in the limit B(sub y) much greater than B(sub n), the mode is strongly stabilized by B(sub n). We report than random pitch angle scattering can overcome the stabilizing effect of B(sub n) and drive the growth rate up toward the Harris neutral sheet (B(sub n) = 0) value when the pitch angle diffusion rate is comparable to Omega(sub n).

Stress and efficiency studies in EFG

NASA Technical Reports Server (NTRS)

1986-01-01

The goals of this program were: (1) to define minimum stress configurations for silicon sheet growth at high speeds; (2) to quantify dislocation electrical activity and their limits on minority carrier diffusion length in deformed silicon; and (3) to study reasons for degradation of lifetime with increases in doping level in edge-defined film-fed growth (EFG) materials. A finite element model was developed for calculating residual stress with plastic deformation. A finite element model was verified for EFG control variable relationships to temperature field of the sheet to permit prediction of profiles and stresses encountered in EFG systems. A residual stress measurement technique was developed for finite size EFG material blanks using shadow Moire interferometry. Transient creep response of silicon was investigated in the temperature range between 800 and 1400 C in strain and strain regimes of interest in stress analysis of sheet growth. Quantitative relationships were established between minority carrier diffusion length and dislocation densities using Electron Beam Induced Current (EBIC) measurement in FZ silicon deformed in four point bending tests.

The quiet evening auroral arc and the structure of the growth phase near-Earth plasma sheet

NASA Astrophysics Data System (ADS)

Coroniti, F. V.; Pritchett, P. L.

2014-03-01

The plasma pressure and current configuration of the near-Earth plasma sheet that creates and sustains the quiet evening auroral arc during the growth phase of magnetospheric substorms is investigated. We propose that the quiet evening arc (QEA) connects to the thin near-Earth current sheet, which forms during the development of the growth phase enhancement of convection. The current sheet's large polarization electric fields are shielded from the ionosphere by an Inverted-V parallel potential drop, thereby producing the electron precipitation responsible for the arc's luminosity. The QEA is located in the plasma sheet region of maximal radial pressure gradient and, in the east-west direction, follows the vanishing of the approximately dawn-dusk-directed gradient or fold in the plasma pressure. In the evening sector, the boundary between the Region1 and Region 2 current systems occurs where the pressure maximizes (approximately radial gradient of the pressure vanishes) and where the approximately radial gradient of the magnetic flux tube volume also vanishes in an inflection region. The proposed intricate balance of plasma sheet pressure and currents may well be very sensitive to disruption by the arrival of equatorward traveling auroral streamers and their associated earthward traveling dipolarization fronts.

Silicon-on-ceramic process: Silicon sheet growth and device development for the large-area silicon sheet task of the low-cost solar array project

NASA Technical Reports Server (NTRS)

Whitehead, A. B.; Zook, J. D.; Grung, B. L.; Heaps, J. D.; Schmit, F.; Schuldt, S. B.; Chapman, P. W.

1981-01-01

The technical feasibility of producing solar cell quality sheet silicon to meet the DOE 1986 cost goal of 70 cents/watt was investigated. The silicon on ceramic approach is to coat a low cost ceramic substrate with large grain polycrystalline silicon by unidirectional solidification of molten silicon. Results and accomplishments are summarized.

Laser-zone growth in a Ribbon-To-Ribbon (RTR) process, silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Gurtler, R. W.; Baghdadi, A.

1976-01-01

The objective of this research is to fully investigate the Ribbon-To-Ribbon (R-T-R) approach to silicon ribbon growth. Initial work has concentrated on modification and characterization of an existing R-T-R apparatus. In addition, equipment for auxiliary heating of the melt is being evaluated and acquired. Modification of the remote viewing system and mechanical staging are nearly complete. Characterization of the laser and other components is in progress and several auxiliary heating techniques are being investigated.

Quantitative analysis of defects in silicon: Silicon sheet growth development for the large area silicon sheet task of the low cost solar array project

NASA Technical Reports Server (NTRS)

Natesh, R.; Smith, J. M.; Qidwai, H. A.

1978-01-01

The various steps involved in the chemical polishing and etching of silicon samples are described and the data on twins, grain boundaries and dislocation pits from fifty-three (53) samples are discussed.

Calcium and zirconium as texture modifiers during rolling and annealing of magnesium–zinc alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bohlen, Jan, E-mail: jan.bohlen@hzg.de; Wendt, Joachim; Nienaber, Maria

2015-03-15

Rolling experiments were carried out on a ternary Mg–Zn–Ca alloy and its modification with zirconium. Short time annealing of as-rolled sheets is used to reveal the microstructure and texture development. The texture of the as-rolled sheets can be characterised by basal pole figures with split peak towards the rolling direction (RD) and a broad transverse angular spread of basal planes towards the transverse direction (TD). During annealing the RD split peaks as well as orientations in the sheet plane vanish whereas the distribution of orientations tilted towards the TD remains. It is shown in EBSD measurements that during rolling bandsmore » of twin containing structures form. During subsequent annealing basal orientations close to the sheet plane vanish based on a grain nucleation and growth mechanism of recrystallisation. Orientations with tilt towards the TD remain in grains that do not undergo such a mechanism. The addition of Zr delays texture weakening. - Highlights: • Ca in Mg–Zn-alloys contributes to a significant texture weakening during rolling and annealing. • Grain nucleation and growth in structures consisting of twins explain a texture randomisation during annealing. • Grains with transverse tilt of basal planes preferentially do not undergo a grain nucleation and growth mechanism. • Zr delays the microstructure and texture development.« less

Increases in plasma sheet temperature with solar wind driving during substorm growth phases

NASA Astrophysics Data System (ADS)

Forsyth, C.; Watt, C. E. J.; Rae, I. J.; Fazakerley, A. N.; Kalmoni, N. M. E.; Freeman, M. P.; Boakes, P. D.; Nakamura, R.; Dandouras, I.; Kistler, L. M.; Jackman, C. M.; Coxon, J. C.; Carr, C. M.

2014-12-01

During substorm growth phases, magnetic reconnection at the magnetopause extracts ~1015 J from the solar wind which is then stored in the magnetotail lobes. Plasma sheet pressure increases to balance magnetic flux density increases in the lobes. Here we examine plasma sheet pressure, density, and temperature during substorm growth phases using 9 years of Cluster data (>316,000 data points). We show that plasma sheet pressure and temperature are higher during growth phases with higher solar wind driving, whereas the density is approximately constant. We also show a weak correlation between plasma sheet temperature before onset and the minimum SuperMAG AL (SML) auroral index in the subsequent substorm. We discuss how energization of the plasma sheet before onset may result from thermodynamically adiabatic processes; how hotter plasma sheets may result in magnetotail instabilities, and how this relates to the onset and size of the subsequent substorm expansion phase.

Increases in plasma sheet temperature with solar wind driving during substorm growth phases

PubMed Central

Forsyth, C; Watt, C E J; Rae, I J; Fazakerley, A N; Kalmoni, N M E; Freeman, M P; Boakes, P D; Nakamura, R; Dandouras, I; Kistler, L M; Jackman, C M; Coxon, J C; Carr, C M

2014-01-01

During substorm growth phases, magnetic reconnection at the magnetopause extracts ∼1015 J from the solar wind which is then stored in the magnetotail lobes. Plasma sheet pressure increases to balance magnetic flux density increases in the lobes. Here we examine plasma sheet pressure, density, and temperature during substorm growth phases using 9 years of Cluster data (>316,000 data points). We show that plasma sheet pressure and temperature are higher during growth phases with higher solar wind driving, whereas the density is approximately constant. We also show a weak correlation between plasma sheet temperature before onset and the minimum SuperMAG AL (SML) auroral index in the subsequent substorm. We discuss how energization of the plasma sheet before onset may result from thermodynamically adiabatic processes; how hotter plasma sheets may result in magnetotail instabilities, and how this relates to the onset and size of the subsequent substorm expansion phase. PMID:26074645

Increases in plasma sheet temperature with solar wind driving during substorm growth phases.

PubMed

Forsyth, C; Watt, C E J; Rae, I J; Fazakerley, A N; Kalmoni, N M E; Freeman, M P; Boakes, P D; Nakamura, R; Dandouras, I; Kistler, L M; Jackman, C M; Coxon, J C; Carr, C M

2014-12-28

During substorm growth phases, magnetic reconnection at the magnetopause extracts ∼10 15  J from the solar wind which is then stored in the magnetotail lobes. Plasma sheet pressure increases to balance magnetic flux density increases in the lobes. Here we examine plasma sheet pressure, density, and temperature during substorm growth phases using 9 years of Cluster data (>316,000 data points). We show that plasma sheet pressure and temperature are higher during growth phases with higher solar wind driving, whereas the density is approximately constant. We also show a weak correlation between plasma sheet temperature before onset and the minimum SuperMAG AL (SML) auroral index in the subsequent substorm. We discuss how energization of the plasma sheet before onset may result from thermodynamically adiabatic processes; how hotter plasma sheets may result in magnetotail instabilities, and how this relates to the onset and size of the subsequent substorm expansion phase.

Development of a program to fit data to a new logistic model for microbial growth.

PubMed

Fujikawa, Hiroshi; Kano, Yoshihiro

2009-06-01

Recently we developed a mathematical model for microbial growth in food. The model successfully predicted microbial growth at various patterns of temperature. In this study, we developed a program to fit data to the model with a spread sheet program, Microsoft Excel. Users can instantly get curves fitted to the model by inputting growth data and choosing the slope portion of a curve. The program also could estimate growth parameters including the rate constant of growth and the lag period. This program would be a useful tool for analyzing growth data and further predicting microbial growth.

Analysis of defect structure in silicon. Silicon sheet growth development for the large area silicon sheet task of the Low-Cost Solar array Project

NASA Technical Reports Server (NTRS)

Natesh, R.; Mena, M.; Plichta, M.; Smith, J. M.; Sellani, M. A.

1982-01-01

One hundred ninety-three silicon sheet samples, approximately 880 square centimeters, were analyzed for twin boundary density, dislocation pit density, and grain boundary length. One hundred fifteen of these samples were manufactured by a heat exchanger method, thirty-eight by edge defined film fed growth, twenty-three by the silicon on ceramics process, and ten by the dendritic web process. Seven solar cells were also step-etched to determine the internal defect distribution on these samples. Procedures were developed or the quantitative characterization of structural defects such as dislocation pits, precipitates, twin & grain boundaries using a QTM 720 quantitative image analyzing system interfaced with a PDP 11/03 mini computer. Characterization of the grain boundary length per unit area for polycrystalline samples was done by using the intercept method on an Olympus HBM Microscope.

Residual-stress-induced grain growth of twinned grains and its effect on formability of magnesium alloy sheet at room temperature

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Se-Jong; Kim, Daeyong, E-mail: daeyong@kims.re.kr; Lee, Keunho

2015-11-15

A magnesium alloy sheet was subjected to in-plane compression along with a vertical load to avoid buckling during compression. Pre-compressed specimens machined from the sheet were annealed at different temperatures and the changes in microstructure and texture were observed using electron back scattered diffraction (EBSD). Twinned grains preferentially grew during annealing at 300 °C, so that a strong texture with the < 0001 > direction parallel to the transverse direction developed. EBSD analysis confirmed that the friction caused by the vertical load induced inhomogeneous distribution of residual stress, which acted as an additional driving force for preferential grain growth ofmore » twinned grain during annealing. The annealed specimen showed excellent formability. - Highlights: • A magnesium alloy sheet subjected to in-plane compression under a vertical load • The vertical load induced inhomogeneous distribution of the residual stress. • The residual stress acted as an additional driving force for grain growth. • The annealed specimen with strong non-basal texture showed excellent formability.« less

Silicon sheet growth development for the large area silicon sheet task of the low cost solar array project. Quantitative analysis of defects in silicon

NASA Technical Reports Server (NTRS)

Natesh, R.

1978-01-01

The various steps involved in obtaining quantitative information of structural defects in crystalline silicon samples are described. Procedures discussed include: (1) chemical polishing; (2) chemical etching; and (3) automated image analysis of samples on the QTM 720 System.

Laser-zone growth in a Ribbon-To-Ribbon (RTR) process. Silicon sheet growth development for the large area sheet task of the low-cost solar array project

NASA Technical Reports Server (NTRS)

Baghdadi, A.; Gurtler, R. W.; Legge, R.; Sopori, B.; Ellis, R. J.

1978-01-01

A new calculation of the effects of thermal stresses during growth on silicon ribbon quality is reported. Thermal stress distributions are computed for ribbon growth under a variety of temperature profiles. A growth rate of 55 cu cm/min with a single ribbon was achieved. The growth of RTR ribbon with a fairly uniform parallel dendritic structure was demonstrated. Results with two approaches were obtained for reducing the Mo impurity level in polycrystalline feedstock. Coating the Mo substrate with Si3N4 does not effect thermal shear separation of the polyribbon; this process shows promise of improving cell efficiency and also increasing the useful life of the molybdenum substrate. A number of solar cells were fabricated on RTR silicon grown from CVD feedstock.

Mechanochemical Modeling of Dynamic Microtubule Growth Involving Sheet-to-Tube Transition

PubMed Central

Ji, Xiang-Ying; Feng, Xi-Qiao

2011-01-01

Microtubule dynamics is largely influenced by nucleotide hydrolysis and the resultant tubulin configuration changes. The GTP cap model has been proposed to interpret the stabilizing mechanisms of microtubule growth from the view of hydrolysis effects. Besides, the growth of a microtubule involves the closure of a curved sheet at its growing end. The curvature conversion from the longitudinal direction to the circumferential direction also helps to stabilize the successive growth, and the curved sheet is referred to as the conformational cap. However, there still lacks theoretical investigation on the mechanical–chemical coupling growth process of microtubules. In this paper, we study the growth mechanisms of microtubules by using a coarse-grained molecular method. First, the closure process involving a sheet-to-tube transition is simulated. The results verify the stabilizing effect of the sheet structure and predict that the minimum conformational cap length that can stabilize the growth is two dimers. Then, we show that the conformational cap and the GTP cap can function independently and harmoniously, signifying the pivotal role of mechanical factors. Furthermore, based on our theoretical results, we describe a Tetris-like growth style of microtubules: the stochastic tubulin assembly is regulated by energy and harmonized with the seam zipping such that the sheet keeps a practically constant length during growth. PMID:22205994

How might the North American ice sheet influence the northwestern Eurasian climate?

NASA Astrophysics Data System (ADS)

Beghin, P.; Charbit, S.; Dumas, C.; Kageyama, M.; Ritz, C.

2015-10-01

It is now widely acknowledged that past Northern Hemisphere ice sheets covering Canada and northern Europe at the Last Glacial Maximum (LGM) exerted a strong influence on climate by causing changes in atmospheric and oceanic circulations. In turn, these changes may have impacted the development of the ice sheets themselves through a combination of different feedback mechanisms. The present study is designed to investigate the potential impact of the North American ice sheet on the surface mass balance (SMB) of the Eurasian ice sheet driven by simulated changes in the past glacial atmospheric circulation. Using the LMDZ5 atmospheric circulation model, we carried out 12 experiments under constant LGM conditions for insolation, greenhouse gases and ocean. In these experiments, the Eurasian ice sheet is removed. The 12 experiments differ in the North American ice-sheet topography, ranging from a white and flat (present-day topography) ice sheet to a full-size LGM ice sheet. This experimental design allows the albedo and the topographic impacts of the North American ice sheet onto the climate to be disentangled. The results are compared to our baseline experiment where both the North American and the Eurasian ice sheets have been removed. In summer, the sole albedo effect of the American ice sheet modifies the pattern of planetary waves with respect to the no-ice-sheet case, resulting in a cooling of the northwestern Eurasian region. By contrast, the atmospheric circulation changes induced by the topography of the North American ice sheet lead to a strong decrease of this cooling. In winter, the Scandinavian and the Barents-Kara regions respond differently to the American ice-sheet albedo effect: in response to atmospheric circulation changes, Scandinavia becomes warmer and total precipitation is more abundant, whereas the Barents-Kara area becomes cooler with a decrease of convective processes, causing a decrease of total precipitation. The gradual increase of the altitude of the American ice sheet leads to less total precipitation and snowfall and to colder temperatures over both the Scandinavian and the Barents and Kara sea sectors. We then compute the resulting annual surface mass balance over the Fennoscandian region from the simulated temperature and precipitation fields used to force an ice-sheet model. It clearly appears that the SMB is dominated by the ablation signal. In response to the summer cooling induced by the American ice-sheet albedo, high positive SMB values are obtained over the Eurasian region, leading thus to the growth of an ice sheet. On the contrary, the gradual increase of the American ice-sheet altitude induces more ablation over the Eurasian sector, hence limiting the growth of Fennoscandia. To test the robustness of our results with respect to the Eurasian ice sheet state, we carried out two additional LMDZ experiments with new boundary conditions involving both the American (flat or full LGM) and high Eurasian ice sheets. The most striking result is that the Eurasian ice sheet is maintained under full-LGM North American ice-sheet conditions, but loses ~ 10 % of its mass compared to the case in which the North American ice sheet is flat. These new findings qualitatively confirm the conclusions from our first series of experiments and suggest that the development of the Eurasian ice sheet may have been slowed down by the growth of the American ice sheet, offering thereby a new understanding of the evolution of Northern Hemisphere ice sheets throughout glacial-interglacial cycles.

Anti-adhesive effects of a newly developed two-layered gelatin sheet in dogs.

PubMed

Torii, Hiroko; Takagi, Toshitaka; Urabe, Mamoru; Tsujimoto, Hiroyuki; Ozamoto, Yuki; Miyamoto, Hiroe; Ikada, Yoshihito; Hagiwara, Akeo

2017-08-01

Adhesion after pelvic surgery causes infertility, ectopic pregnancy, and ileus or abdominal pain. The materials currently available for clinical use are insufficient. The purpose of this study was to develop an anti-adhesive material that overcomes the limitations of conventional anti-adhesive agents. The adhesion prevention effects of three methods - a two-layered sheet composed of gelatin film and gelatin sponge, Seprafilm and INTERCEED - were evaluated in 37 dogs. Anti-adhesive effects were investigated macroscopically and microscopically in a cauterized uterus adhesion model. Cell growth on the materials in vitro using human peritoneal mesothelial cells, fibroblasts and uterine smooth muscle cells were also evaluated. The two-layered gelatin sheet had significantly superior anti-adhesive effects compared to the conventional materials (Seprafilm and INTERCEED). A single-cell layer of mature mesothelium formed three weeks after surgery in the gelatin group. Peritoneum regeneration in the Seprafilm and INTERCEED groups was delayed and incomplete in the early phase. Little inflammation around the materials occurred and cell growth was significantly proliferated with the gelatin sheet. The anti-adhesive effects of a two-layered gelatin sheet were superior to conventional agents in a cauterized canine uterus model, demonstrating early regeneration of the peritoneum, little inflammation and material endurance. The newly developed two-layered gelatin sheet is a useful option as an anti-adhesive agent for deeply injured and hemorrhagic sites. © 2017 The Authors. Journal of Obstetrics and Gynaecology Research published by John Wiley & Sons Australia, Ltd on behalf of Japan Society of Obstetrics and Gynecology.

Self-assembly of peptide-amphiphile nanofibers under physiological conditions

DOEpatents

Stupp, Samuel I [Chicago, IL; Hartgerink, Jeffrey D [Pearland, TX; Beniash, Elia [Auburndale, MA

2011-11-22

The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micellar nanofiber composed of beta-sheets, which promote neuron growth and development.

A Technique for the Growth of Epidermal Sheets Obtained from Patients Undergoing Reduction Mammoplasty.

DTIC Science & Technology

1991-03-06

flask with Dispase, a neutral protease and attached to petrolatum gauze. At this point the sheets could be used as skin grafts . Progress: 1...a composite in vitro skin graft . We believe that development of an artificial dermis as part of a composite in vitro graft is where our future

Modular control of endothelial sheet migration

PubMed Central

Vitorino, Philip; Meyer, Tobias

2008-01-01

Growth factor-induced migration of endothelial cell monolayers enables embryonic development, wound healing, and angiogenesis. Although collective migration is widespread and therapeutically relevant, the underlying mechanism by which cell monolayers respond to growth factor, sense directional signals, induce motility, and coordinate individual cell movements is only partially understood. Here we used RNAi to identify 100 regulatory proteins that enhance or suppress endothelial sheet migration into cell-free space. We measured multiple live-cell migration parameters for all siRNA perturbations and found that each targeted protein primarily regulates one of four functional outputs: cell motility, directed migration, cell–cell coordination, or cell density. We demonstrate that cell motility regulators drive random, growth factor-independent motility in the presence or absence of open space. In contrast, directed migration regulators selectively transduce growth factor signals to direct cells along the monolayer boundary toward open space. Lastly, we found that regulators of cell–cell coordination are growth factor-independent and reorient randomly migrating cells inside the sheet when boundary cells begin to migrate. Thus, cells transition from random to collective migration through a modular control system, whereby growth factor signals convert boundary cells into pioneers, while cells inside the monolayer reorient and follow pioneers through growth factor-independent migration and cell–cell coordination. PMID:19056882

Regulation of Transforming Growth Factor β1, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring.

PubMed

Choi, Jaehoon; Lee, Eun Hee; Park, Sang Woo; Chang, Hak

2015-01-01

Hypertrophic scars and keloids are associated with abnormal levels of growth factors. Silicone gel sheets are effective in treating and preventing hypertrophic scars and keloids. There has been no report on the change in growth factors in the scar tissue following the use of silicone gel sheeting for scar prevention. A prospective controlled trial was performed to evaluate whether growth factors are altered by the application of a silicone gel sheet on a fresh surgical scar. Four of seven enrolled patients completed the study. Transforming growth factor (TGF)-β1, platelet-derived growth factor (PDGF), and basic fibroblast growth factor (bFGF) were investigated immunohistochemically in biopsies taken from five scars at 4 months following surgery. In both the epidermis and the dermis, the expression of TGF-β1 (P=0.042 and P=0.042) and PDGF (P=0.043 and P=0.042) was significantly lower in the case of silicone gel sheet-treated scars than in the case of untreated scars. The expression of bFGF in the dermis was significantly higher in the case of silicone gel sheet-treated scars than in the case of untreated scars (P=0.042), but in the epidermis, the expression of bFGF showed no significant difference between the groups (P=0.655). The levels of TGF-β1, PDGF, and bFGF are altered by the silicone gel sheet treatment, which might be one of the mechanisms of action in scar prevention.

Convection Constraints and Current Sheet Thinning During the Substorm Growth Phase

NASA Astrophysics Data System (ADS)

Otto, A.; Hsieh, M.

2012-12-01

A typical property during the growth phase of geomagnetic substorms is the thinning of the near-Earth current sheet, most pronounced in the region between 6 and 15 RE. We propose that the cause for this current sheet thinning is convection from the midnight tail region to the dayside to replenish magnetospheric magnetic flux that is eroded at the dayside as a result of dayside reconnection. Slow (adiabatic) convection from the near-Earth tail region toward the dayside must conserve the entropy on magnetic field lines. This constraint prohibits a source of magnetic flux from a region further out in the magnetotail. Thus the near-Earth tail region is increasingly depleted of magnetic flux (the Erickson and Wolf [1980] problem) with entropy matching that of flux tubes that are eroded on the dayside. It is proposed that the magnetic flux depletion in the near-Earth tail forces the formation of thin current layers. The process is illustrated and examined by three-dimensional meso-scale MHD simulations. It is shown that the simulations yield a time scale, location, and other general characteristics of the current sheet evolution consistent with observations during the substorm growth phase. The developing thin current sheet is easily destabilized and can undergo localized reconnection events. We present properties of the thinning current sheet, the associated entropy evolution, examples of localized reconnection onset and we discuss the dependence of this process on external parameters such the global reconnection rate.

The Gamburtsev mountains and the origin and early evolution of the Antarctic Ice Sheet.

PubMed

Bo, Sun; Siegert, Martin J; Mudd, Simon M; Sugden, David; Fujita, Shuji; Xiangbin, Cui; Yunyun, Jiang; Xueyuan, Tang; Yuansheng, Li

2009-06-04

Ice-sheet development in Antarctica was a result of significant and rapid global climate change about 34 million years ago. Ice-sheet and climate modelling suggest reductions in atmospheric carbon dioxide (less than three times the pre-industrial level of 280 parts per million by volume) that, in conjunction with the development of the Antarctic Circumpolar Current, led to cooling and glaciation paced by changes in Earth's orbit. Based on the present subglacial topography, numerical models point to ice-sheet genesis on mountain massifs of Antarctica, including the Gamburtsev mountains at Dome A, the centre of the present ice sheet. Our lack of knowledge of the present-day topography of the Gamburtsev mountains means, however, that the nature of early glaciation and subsequent development of a continental-sized ice sheet are uncertain. Here we present radar information about the base of the ice at Dome A, revealing classic Alpine topography with pre-existing river valleys overdeepened by valley glaciers formed when the mean summer surface temperature was around 3 degrees C. This landscape is likely to have developed during the initial phases of Antarctic glaciation. According to Antarctic climate history (estimated from offshore sediment records) the Gamburtsev mountains are probably older than 34 million years and were the main centre for ice-sheet growth. Moreover, the landscape has most probably been preserved beneath the present ice sheet for around 14 million years.

Interfacial growth of large-area single-layer metal-organic framework nanosheets

PubMed Central

Makiura, Rie; Konovalov, Oleg

2013-01-01

The air/liquid interface is an excellent platform to assemble two-dimensional (2D) sheets of materials by enhancing spontaneous organizational features of the building components and encouraging large length scale in-plane growth. We have grown 2D molecularly-thin crystalline metal-organic-framework (MOF) nanosheets composed of porphyrin building units and metal-ion joints (NAFS-13) under operationally simple ambient conditions at the air/liquid interface. In-situ synchrotron X-ray diffraction studies of the formation process performed directly at the interface were employed to optimize the NAFS-13 growth protocol leading to the development of a post-injection method –post-injection of the metal connectors into the water subphase on whose surface the molecular building blocks are pre-oriented– which allowed us to achieve the formation of large-surface area morphologically-uniform preferentially-oriented single-layer nanosheets. The growth of such large-size high-quality sheets is of interest for the understanding of the fundamental physical/chemical properties associated with ultra-thin sheet-shaped materials and the realization of their use in applications. PMID:23974345

Fatigue crack growth in 2024-T3 aluminum under tensile and transverse shear stresses

NASA Technical Reports Server (NTRS)

Viz, Mark J.; Zehnder, Alan T.

1994-01-01

The influence of transverse shear stresses on the fatigue crack growth rate in thin 2024-T3 aluminum alloy sheets is investigated experimentally. The tests are performed on double-edge cracked sheets in cyclic tensile and torsional loading. This loading generates crack tip stress intensity factors in the same ratio as the values computed for a crack lying along a lap joint in a pressurized aircraft fuselage. The relevant fracture mechanics of cracks in thin plates along with the details of the geometrically nonlinear finite element analyses used for the test specimen calibration are developed and discussed. Preliminary fatigue crack growth data correlated using the fully coupled stress intensity factor calibration are presented and compared with fatigue crack growth data from pure delta K(sub I)fatigue tests.

Proceedings of the 25th Project Integration Meeting

NASA Technical Reports Server (NTRS)

Phillips, M.

1985-01-01

Topics addressed include: silicon sheet growth and characterization, silicon material, process development, high-efficiency cells, environmental isolation, engineering sciences, and reliability physics.

Effects of transverse temperature field nonuniformity on stress in silicon sheet growth

NASA Technical Reports Server (NTRS)

Mataga, P. A.; Hutchinson, J. W.; Chalmers, B.; Bell, R. O.; Kalejs, J. P.

1987-01-01

Stress and strain rate distributions are calculated using finite element analysis for steady-state growth of thin silicon sheet temperature nonuniformities imposed in the transverse (sheet width) dimension. Significant reductions in residual stress are predicted to occur for the case where the sheet edge is cooled relative to its center provided plastic deformation with high creep rates is present.

Quantitative Analysis of Defects in Silicon. Silicon Sheet Growth Development for the Large Area Silicon Sheet Task of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Natesh, R.; Smith, J. M.; Qidwai, H. A.

1979-01-01

The various steps involved in the chemical polishing and etching of silicon samples are described. Data on twins, dislocation pits, and grain boundaries from thirty-one (31) silicon sample are also discussed. A brief review of the changes made to upgrade the image analysis system is included.

The Effects of Grain Size and Texture on Dynamic Abnormal Grain Growth in Mo

NASA Astrophysics Data System (ADS)

Noell, Philip J.; Taleff, Eric M.

2016-10-01

This is the first report of abnormal grain morphologies specific to a Mo sheet material produced from a commercial-purity arc-melted ingot. Abnormal grains initiated and grew during plastic deformation of this material at temperatures of 1793 K and 1813 K (1520 °C and 1540 °C). This abnormal grain growth during high-temperature plastic deformation is termed dynamic abnormal grain growth, DAGG. DAGG in this material readily consumes nearly all grains near the sheet center while leaving many grains near the sheet surface unconsumed. Crystallographic texture, grain size, and other microstructural features are characterized. After recrystallization, a significant through-thickness variation in crystallographic texture exists in this material but does not appear to directly influence DAGG propagation. Instead, dynamic normal grain growth, which may be influenced by texture, preferentially occurs near the sheet surface prior to DAGG. The large grains thus produced near the sheet surface inhibit the subsequent growth of the abnormal grains produced by DAGG, which preferentially consume the finer grains near the sheet center. This produces abnormal grains that span the sheet center but leave unconsumed polycrystalline microstructure near the sheet surface. Abnormal grains are preferentially oriented with the < 110rangle approximately along the tensile axis. These results provide additional new evidence that boundary curvature is the primary driving force for DAGG in Mo.

Quantitative analysis of defects in silicon. Silicon sheet growth development for the large are silicon sheet task of the low-cost solar array project

NASA Technical Reports Server (NTRS)

Natesh, R.; Smith, J. M.; Bruce, T.; Oidwai, H. A.

1980-01-01

One hundred and seventy four silicon sheet samples were analyzed for twin boundary density, dislocation pit density, and grain boundary length. Procedures were developed for the quantitative analysis of the twin boundary and dislocation pit densities using a QTM-720 Quantitative Image Analyzing system. The QTM-720 system was upgraded with the addition of a PDP 11/03 mini-computer with dual floppy disc drive, a digital equipment writer high speed printer, and a field-image feature interface module. Three versions of a computer program that controls the data acquisition and analysis on the QTM-720 were written. Procedures for the chemical polishing and etching were also developed.

Stability of Thin Liquid Sheet Flows

NASA Technical Reports Server (NTRS)

McConley, Marc W.; Chubb, Donald L.; McMaster, Matthew S.; Afjeh, Abdollah A.

1997-01-01

A two-dimensional, linear stability analysis of a thin nonplanar liquid sheet flow in vacuum is carried out. A sheet flow created by a narrow slit of W and tau attains a nonplanar cross section as a consequence of cylinders forming on the sheet edge under the influence of surface tension forces. The region where these edge cylinders join the sheet is one of high curvature, and this is found to be the location where instability is most likely to occur. The sheet flow is found to be unstable, but with low growth rates for symmetric wave disturbances and high growth rates for antisymmetric disturbances. By combining the symmetric and antisymmetric disturbance modes, a wide range of stability characteristics is obtained. The product of unstable growth rate and flow time is proportional to the width-to-thickness ratio of the sift generating the sheet Three-dimensional effects can alter these results, particularly when the sheet length-to-width ratio is not much greater than unity.

Continuous Czochralski growth: Silicon sheet growth development of the large area sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Johnson, C. M.

1980-01-01

The growth of 100 kg of silicon single crystal material, ten cm in diameter or greater, and 150 kg of silicon single crystal material 15 cm or greater utilizing one common silicon container material (one crucible) is investigated. A crystal grower that is recharged with a new supply of polysilicon material while still under vacuum and at temperatures above the melting point of silicon is developed. It accepts large polysilicon charges up to 30 kg, grows large crystal ingots (to 15 cm diameter and 25 kg in weight), and holds polysilicon material for recharging (rod or lump) while, at the same time, growing crystal ingots. Special equipment is designed to recharge polysilicon rods, recharge polysilicon lumps, and handle and store large, hot silicon crystal ingots. Many continuous crystal growth runs were performed lasting as long as 109 hours and producing as many as ten crystal ingots, 15 cm with weights progressing to 27 kg.

Laser-zone growth in a Ribbon-To-Ribbon, RTR, process silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Gurtler, R. W.; Baghdadi, A.

1977-01-01

A ribbon-to-ribbon process was used for routine growth of samples for analysis and fabrication into solar cells. One lot of solar cells was completely evaluated: ribbon solar cell efficiencies averaged 9.23% with a highest efficiency of 11.7%. Spherical reflectors have demonstrated significant improvements in laser silicon coupling efficiencies. Material analyses were performed including silicon photovoltage and open circuit photovoltage diffusion length measurements, crystal morphology studies, modulus of rupture measurements, and annealing/gettering studies. An initial economic analysis was performed indicating that ribbon-to-ribbon add-on costs of $.10/watt might be expected in the early 1980's.

Heat exchanger-ingot casting/slicing process, phase 1: Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Schmid, F.; Khattak, C. P.

1977-01-01

A controlled growth, heat-flow and cool-down process is described that yielded silicon with a high degree of single crystallinity. Even when the seed melted out, very large grains formed. Solar cell samples made from cast material yielded conversion efficiency of over 9%. Representative characterizations of grown silicon demonstrated a dislocation density of less than 100/sq cm and a minority carrier diffusion length of 31 micron. The source of silicon carbide in silicon ingots was identified to be from graphite retainers in contact with silica crucibles. Higher growth rates were achieved with the use of a graphite plug at the bottom of the silica crucible.

Crystal growth for high-efficiency silicon solar cells workshop: Summary

NASA Technical Reports Server (NTRS)

Dumas, K. A.

1985-01-01

The state of the art in the growth of silicon crystals for high-efficiency solar cells are reviewed, sheet requirements are defined, and furture areas of research are identified. Silicon sheet material characteristics that limit cell efficiencies and yields were described as well as the criteria for the ideal sheet-growth method. The device engineers wish list to the material engineer included: silicon sheet with long minority carrier lifetime that is uniform throughout the sheet, and which doesn't change during processing; and sheet material that stays flat throughout device processing, has uniform good mechanical strength, and is low cost. Impurities in silicon solar cells depreciate cell performance by reducing diffusion length and degrading junctions. The impurity behavior, degradation mechanisms, and variations in degradation threshold with diffusion length for silicon solar cells were described.

Laser-zone growth in a Ribbon-To-Ribbon (RTR) process. Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Gurtler, R. W.; Baghdadi, A.; Legge, R.; Sopori, B.; Ellis, R. J.

1977-01-01

The Ribbon-to-Ribbon (RTR) approach to silicon ribbon growth is investigated. An existing RTR apparatus is to be upgraded to its full capabilities and operated routinely to investigate and optimize the effects of various growth parameters on growth results. A new RTR apparatus was constructed to incorporate increased capabilities and improvements over the first apparatus and to be capable of continuous growth. New high power lasers were implemented and this led to major improvements in growth velocity -- 4 inch/min. growth has been demonstrated. A major step in demonstration of the full feasibility of the RTR process is reported in the demonstration of RTR growth from CVD polyribbon rather than sliced polyribbon ingots. Average solar cell efficiencies of greater than 9% and a best cell efficiency of 11.7% are reported. Processing was shown to provide a substantial improvement in material minority carrier diffusion length. An economic analysis is reported which treats both the polyribbon fabrication and RTR processes.

Practical aspects of running DOE for improving growth media for in vitro plants

USDA-ARS?s Scientific Manuscript database

Experiments using DOE software to improve plant tissue culture growth medium are complicated and require complex setups. Once the experimental design is set and the treatment points calculated, media sheets and mixing charts must be developed. Since these experiments require three passages on the sa...

Analysis of high-speed growth of silicon sheet in inclined-meniscus configuration

NASA Technical Reports Server (NTRS)

Thomas, P. D.; Brown, R. A.

1985-01-01

The study of high speed growth of silicon sheet in inclined-meniscus configurations is discussed. It was concluded that the maximum growth rates in vertical and inclined growth are set by thermal-capillary limits. Also, the melt/crystal interface was determined to be flat. And, vertical growth is qualitatively modelled by one dimensional heat transfer.

Development and characterization of hybrid tubular structure of PLCL porous scaffold with hMSCs/ECs cell sheet.

PubMed

Pangesty, Azizah Intan; Arahira, Takaaki; Todo, Mitsugu

2017-09-15

Tissue engineering offers an alternate approach to providing vascular graft with potential to grow similar with native tissue by seeding autologous cells into biodegradable scaffold. In this study, we developed a combining technique by layering a sheet of cells onto a porous tubular scaffold. The cell sheet prepared from co-culturing human mesenchymal stem cells (hMSCs) and endothelial cells (ECs) were able to infiltrate through porous structure of the tubular poly (lactide-co-caprolactone) (PLCL) scaffold and further proliferated on luminal wall within a week of culture. Moreover, the co-culture cell sheet within the tubular scaffold has demonstrated a faster proliferation rate than the monoculture cell sheet composed of MSCs only. We also found that the co-culture cell sheet expressed a strong angiogenic marker, including vascular endothelial growth factor (VEGF) and its receptor (VEGFR), as compared with the monoculture cell sheet within 2 weeks of culture, indicating that the co-culture system could induce differentiation into endothelial cell lineage. This combined technique would provide cellularization and maturation of vascular construct in relatively short period with a strong expression of angiogenic properties.

Dip-coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Zook, J. D.; Heaps, J. D.; Maciolek, R. B.; Koepke, B. G.; Gutter, C. D.; Schuldt, S. B.

1977-01-01

The objective of this research program is to investigate the technical and economic feasibility of producing solar-cell-quality sheet silicon by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. The past quarter demonstrated significant progress in several areas. Seeded growth of silicon-on-ceramic (SOC) with an EFG ribbon seed was demonstrated. Different types of mullite were successfully coated with silicon. A new method of deriving minority carrier diffusion length, L sub n from spectral response measurements was evaluated. ECOMOD cost projections were found to be in good agreement with the interim SAMIS method proposed by JPL. On the less positive side, there was a decrease in cell performance which we believe to be due to an unidentified source of impurities.

Hot forming of silicon sheet, silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Graham, C. D., Jr.; Pope, D. P.; Kulkarni, S.; Wolf, M.

1978-01-01

The hot workability of polycrystalline silicon was studied. Uniaxail stress-strain curves are given for strain rates in the range of .0001 to .1/sec and temperatures from 1100 to 1380 C. At the highest strain rates at 1380 C axial strains in excess of 20% were easily obtainable without cracking. After deformations of 36%, recrystallization was completed within 0.1 hr at 1380 C. When the recrystallization was complete, there was still a small volume fraction of unrecyrstallized material which appeared very stable and may degrade the electronic properties of the bulk materials. Texture measurements showed that the as-produced vapor deposited polycrystalline rods have a 110 fiber texture with the 110 direction parallel to the growth direction and no preferred orientation about this axis. Upon axial compression perpendicular to the growth direction, the former 110 fiber axis changed to 111 and the compression axis became 110 . Recrystallization changed the texture to 110 along the former fiber axis and to 100 along the compression axis.

Continuous Czochralski growth: Silicon sheet growth development of the large area silicon sheet task of the Low Cost Silicon Solar Array project

NASA Technical Reports Server (NTRS)

1978-01-01

The primary objective of this contract is to develop equipment and methods for the economic production of single crystal ingot material by the continuous Czochralski (CZ) process. Continuous CZ is defined for the purpose of this work as the growth of at least 100 kilograms of ingot from only one melt container. During the reporting period (October, 1977 - September, 1978), a modified grower was made fully functional and several recharge runs were performed. The largest run lasted 44 hours and over 42 kg of ingot was produced. Little, if any, degradation in efficiency was observed as a result of pulling multiple crystals from one crucible. Solar efficiencies observed were between 9.3 and 10.4% AMO (13.0 and 14.6% AMI) compared to 10.5% (14.7% AMI) for optimum CZ material control samples. Using the SAMICS/IPEG format, economic analysis of continuous CZ suggests that 1986 DoE cost goals can only be met by the growth of large diameter, large mass crystals.

Dynamics of a radially expanding liquid sheet: Experiments

NASA Astrophysics Data System (ADS)

Majumdar, Nayanika; Tirumkudulu, Mahesh

2017-11-01

A recent theory predicts that sinuous waves generated at the center of a radially expanding liquid sheet grow spatially even in absence of a surrounding gas phase. Unlike flat liquid sheets, the thickness of a radially expanding liquid sheet varies inversely with distance from the center of the sheet. To test the predictions of the theory, experiments were carried out on a horizontal, radially expanding liquid sheet formed by collision of a single jet on a solid impactor. The latter was placed on a speaker-vibrator with controlled amplitude and frequency. The growth of sinuous waves was determined by measuring the wave surface inclination angle using reflected laser light under both atmospheric and sub-atmospheric pressure conditions. It is shown that the measured growth rate matches with the predictions of the theory over a large range of Weber numbers for both pressure conditions suggesting that the thinning of the liquid sheet plays a dominant role in setting the growth rate of sinuous waves with minimal influence of the surrounding gas phase on its dynamics. IIT Bombay.

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D. L.; Schruben, J.

1982-01-01

Thermal models were developed that accurately predict the thermally generated stresses in the web crystal which, if too high, cause the crystal to degenerate. The application of the modeling results to the design of low-stress experimental growth configurations will allow the growth of wider web crystals at higher growth velocities. A new experimental web growth machine was constructed. This facility includes all the features necessary for carrying out growth experiments under steady thermal conditions. Programmed growth initiation was developed to give reproducible crystal starts. Width control permits the growth of long ribbons at constant width. Melt level is controlled to 0.1 mm or better. Thus, the capability exists to grow long web crystals of constant width and thickness with little operator intervention, and web growth experiments can now be performed with growth variables controlled to a degree not previously possible.

Rate limits in silicon sheet growth - The connections between vertical and horizontal methods

NASA Technical Reports Server (NTRS)

Thomas, Paul D.; Brown, Robert A.

1987-01-01

Meniscus-defined techniques for the growth of thin silicon sheets fall into two categories: vertical and horizontal growth. The interactions of the temperature field and the crystal shape are analyzed for both methods using two-dimensional finite-element models which include heat transfer and capillarity. Heat transfer in vertical growth systems is dominated by conduction in the melt and the crystal, with almost flat melt/crystal interfaces that are perpendicular to the direction of growth. The high axial temperature gradients characteristic of vertical growth lead to high thermal stresses. The maximum growth rate is also limited by capillarity which can restrict the conduction of heat from the melt into the crystal. In horizontal growth the melt/crystal interface stretches across the surface of the melt pool many times the crystal thickness, and low growth rates are achievable with careful temperature control. With a moderate axial temperature gradient in the sheet a substantial portion of the latent heat conducts along the sheet and the surface of the melt pool becomes supercooled, leading to dendritic growth. The thermal supercooling is surpressed by lowering the axial gradient in the crystal; this configuration is the most desirable for the growth of high quality crystals. An expression derived from scaling analysis relating the growth rate and the crucible temperature is shown to be reliable for horizontal growth.

The use of platelet-rich fibrin combined with periodontal ligament and jaw bone mesenchymal stem cell sheets for periodontal tissue engineering.

PubMed

Wang, Zhong-Shan; Feng, Zhi-Hong; Wu, Guo-Feng; Bai, Shi-Zhu; Dong, Yan; Chen, Fa-Ming; Zhao, Yi-Min

2016-06-21

Periodontal regeneration involves the restoration of at least three unique tissues: cementum, periodontal ligament tissue (PDL) and alveolar bone tissue. Here, we first isolated human PDL stem cells (PDLSCs) and jaw bone mesenchymal stem cells (JBMSCs). These cells were then induced to form cell sheets using an ascorbic acid-rich approach, and the cell sheet properties, including morphology, thickness and gene expression profile, were compared. Platelet-rich fibrin (PRF) derived from human venous blood was then fabricated into bioabsorbable fibrin scaffolds containing various growth factors. Finally, the in vivo potential of a cell-material construct based on PDLSC sheets, PRF scaffolds and JBMSC sheets to form periodontal tissue was assessed in a nude mouse model. In this model, PDLSC sheet/PRF/JBMSC sheet composites were placed in a simulated periodontal space comprising human treated dentin matrix (TDM) and hydroxyapatite (HA)/tricalcium phosphate (TCP) frameworks. Eight weeks after implantation, the PDLSC sheets tended to develop into PDL-like tissues, while the JBMSC sheets tended to produce predominantly bone-like tissues. In addition, the PDLSC sheet/PRF/JBMSC sheet composites generated periodontal tissue-like structures containing PDL- and bone-like tissues. Further improvements in this cell transplantation design may have the potential to provide an effective approach for future periodontal tissue regeneration.

Large area silicon sheet by EFG. [Edge-defined Film-fed Growth

NASA Technical Reports Server (NTRS)

Rao, C. V. H.; Surek, T.; Mackintosh, B.; Ravi, K. V.; Wald, F. V.

1978-01-01

The edge-defined, film-fed growth (EFG) technique has been employed to grow silicon ribbons for photovoltaic applications. Considerable progress has been made in recent years in developing the technique to the point that long lengths of silicon ribbon can be routinely grown. In order to attain the full low-cost potential of the EFG technique, several further developments such as the growth of thinner and wider ribbons, increase in ribbon growth rate, and improvements in material quality are needed. The technological problems to be solved and the approaches employed to achieve these goals are discussed.

Large area sheet task. Advanced dendritic web growth development. [silicon films

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Frantti, E.; Schruben, J.

1981-01-01

The development of a silicon dendritic web growth machine is discussed. Several refinements to the sensing and control equipment for melt replenishment during web growth are described and several areas for cost reduction in the components of the prototype automated web growth furnace are identified. A circuit designed to eliminate the sensitivity of the detector signal to the intensity of the reflected laser beam used to measure melt level is also described. A variable speed motor for the silicon feeder is discussed which allows pellet feeding to be accomplished at a rate programmed to match exactly the silicon removed by web growth.

Exploring Explanations of Subglacial Bedform Sizes Using Statistical Models.

PubMed

Hillier, John K; Kougioumtzoglou, Ioannis A; Stokes, Chris R; Smith, Michael J; Clark, Chris D; Spagnolo, Matteo S

2016-01-01

Sediments beneath modern ice sheets exert a key control on their flow, but are largely inaccessible except through geophysics or boreholes. In contrast, palaeo-ice sheet beds are accessible, and typically characterised by numerous bedforms. However, the interaction between bedforms and ice flow is poorly constrained and it is not clear how bedform sizes might reflect ice flow conditions. To better understand this link we present a first exploration of a variety of statistical models to explain the size distribution of some common subglacial bedforms (i.e., drumlins, ribbed moraine, MSGL). By considering a range of models, constructed to reflect key aspects of the physical processes, it is possible to infer that the size distributions are most effectively explained when the dynamics of ice-water-sediment interaction associated with bedform growth is fundamentally random. A 'stochastic instability' (SI) model, which integrates random bedform growth and shrinking through time with exponential growth, is preferred and is consistent with other observations of palaeo-bedforms and geophysical surveys of active ice sheets. Furthermore, we give a proof-of-concept demonstration that our statistical approach can bridge the gap between geomorphological observations and physical models, directly linking measurable size-frequency parameters to properties of ice sheet flow (e.g., ice velocity). Moreover, statistically developing existing models as proposed allows quantitative predictions to be made about sizes, making the models testable; a first illustration of this is given for a hypothesised repeat geophysical survey of bedforms under active ice. Thus, we further demonstrate the potential of size-frequency distributions of subglacial bedforms to assist the elucidation of subglacial processes and better constrain ice sheet models.

Identification of Biomarkers for Footpad Dermatitis Development and Wound Healing

PubMed Central

Chen, Juxing; Tellez, Guillermo; Escobar, Jeffery

2016-01-01

Footpad dermatitis (FPD) is a type of skin inflammation that causes necrotic lesions on the plantar surface of the footpads in commercial poultry, with significant animal welfare, and economic implications. To identify biomarkers for FPD development and wound healing, a battery cage trial was conducted in which a paper sheet was put on the bottom of cages to hold feces to induce FPD of broilers. Day-of-hatch Ross 308 male broiler chicks were fed a corn–soybean meal diet and assigned to 3 treatments with 8 cages per treatment and 11 birds per cage. Cages without paper sheets were used as a negative control (NEG). Cages with paper sheets during the entire growth period (d 0–30) were used as a positive control (POS) to continually induce FPD. Cages with paper sheets during d 0–13 and without paper sheets during d 14–30 were used to examine the dynamic of FPD development and lesion wound healing (LWH). Footpad lesions were scored to grade (G) 1–5 with no lesion in G1 and most severe lesion in G5. Covering with paper sheets in POS and LWH induced 99% incidence of G3 footpads on d 13. Removing paper sheets from LWH healed footpad lesions by d 30. One representative bird, with lesions most close to pen average lesion score, was chosen to collect footpad skin samples for biomarker analysis. Total collagen protein and mRNA levels of tenascin X (TNX), type I α1 collagen (COL1A1), type III α1 collagen (COL3A1), tissue inhibitor of metalloproteinase 3 (TIMP3), and integrin α1 (ITGA1) mRNA levels were decreased (P < 0.05), while mRNA levels of tenascin C (TNC), tumor necrosis factor (TNF) α, Toll-like receptor (TLR) 4 and vascular endothelial growth factor (VEGF), IL-1β, and the ratio of MMP2 to all TIMP were increased (P < 0.03) in G3 footpads in POS and LWH compared to G1 footpads in NEG on d 14. These parameters continued to worsen with development of more severe lesions in POS. After paper sheets were removed (i.e., LWH), levels of these parameters gradually or rapidly returned to levels measured in NEG. Regression analysis indicated significant quadratic changes of these parameters to footpad lesion scores. In summary, these biomarkers were interrelated with dynamic changes of footpad lesion scores, suggesting they may be used as potential biomarkers for footpad lesion development and wound healing process. PMID:26973819

U.S. Government Supports Low Emission Economic Growth (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, A.; Sandor, D.; Butheau, M.

Countries around the world face the challenge of maintaining long-term sustainable economic growth and development under the threat of climate change. By identifying and pursuing a sustainable development pathway now, they are better positioned to reach their economic growth goals while addressing climate change impacts and lowering greenhouse gas (GHG) emissions. Low emission development strategies - development plans that promote sustainable social and economic development while reducing long-term GHG emissions - provide a pathway to preparing for a global low emission future. Partner country governments are working with the U.S. government through the Enhancing Capacity for Low Emission Development Strategiesmore » (EC-LEDS) program to further their national development objectives.« less

Growth patterns for shape-shifting elastic bilayers.

PubMed

van Rees, Wim M; Vouga, Etienne; Mahadevan, L

2017-10-31

Inspired by the differential-growth-driven morphogenesis of leaves, flowers, and other tissues, there is increasing interest in artificial analogs of these shape-shifting thin sheets made of active materials that respond to environmental stimuli such as heat, light, and humidity. But how can we determine the growth patterns to achieve a given shape from another shape? We solve this geometric inverse problem of determining the growth factors and directions (the metric tensors) for a given isotropic elastic bilayer to grow into a target shape by posing and solving an elastic energy minimization problem. A mathematical equivalence between bilayers and curved monolayers simplifies the inverse problem considerably by providing algebraic expressions for the growth metric tensors in terms of those of the final shape. This approach also allows us to prove that we can grow any target surface from any reference surface using orthotropically growing bilayers. We demonstrate this by numerically simulating the growth of a flat sheet into a face, a cylindrical sheet into a flower, and a flat sheet into a complex canyon-like structure.

Growth patterns for shape-shifting elastic bilayers

PubMed Central

van Rees, Wim M.; Vouga, Etienne; Mahadevan, L.

2017-01-01

Inspired by the differential-growth-driven morphogenesis of leaves, flowers, and other tissues, there is increasing interest in artificial analogs of these shape-shifting thin sheets made of active materials that respond to environmental stimuli such as heat, light, and humidity. But how can we determine the growth patterns to achieve a given shape from another shape? We solve this geometric inverse problem of determining the growth factors and directions (the metric tensors) for a given isotropic elastic bilayer to grow into a target shape by posing and solving an elastic energy minimization problem. A mathematical equivalence between bilayers and curved monolayers simplifies the inverse problem considerably by providing algebraic expressions for the growth metric tensors in terms of those of the final shape. This approach also allows us to prove that we can grow any target surface from any reference surface using orthotropically growing bilayers. We demonstrate this by numerically simulating the growth of a flat sheet into a face, a cylindrical sheet into a flower, and a flat sheet into a complex canyon-like structure. PMID:29078336

Nucleation and Growth of Insulin Fibrils in Bulk Solution and at Hydrophobic Polystyrene Surfaces

PubMed Central

Smith, M. I.; Sharp, J. S.; Roberts, C. J.

2007-01-01

A technique was developed for studying the nucleation and growth of fibrillar protein aggregates. Fourier transform infrared and attenuated total reflection spectroscopy were used to measure changes in the intermolecular β-sheet content of bovine pancreatic insulin in bulk solution and on model polystyrene (PS) surfaces at pH 1. The kinetics of β-sheet formation were shown to evolve in two stages. Combined Fourier transform infrared, dynamic light scattering, atomic force microscopy, and thioflavin-T fluorescence measurements confirmed that the first stage in the kinetics was related to the formation of nonfibrillar aggregates that have a radius of 13 ± 1 nm. The second stage was found to be associated with the growth of insulin fibrils. The β-sheet kinetics in this second stage were used to determine the nucleation and growth rates of fibrils over a range of temperatures between 60°C and 80°C. The nucleation and growth rates were shown to display Arrhenius kinetics, and the associated energy barriers were extracted for fibrils formed in bulk solution and at PS surfaces. These experiments showed that fibrils are nucleated more quickly in the presence of hydrophobic PS surfaces but that the corresponding fibril growth rates decrease. These observations are interpreted in terms of the differences in the attempt frequencies and energy barriers associated with the nucleation and growth of fibrils. They are also discussed in the context of differences in protein concentration, mobility, and conformational and colloidal stability that exist between insulin molecules in bulk solution and those that are localized at hydrophobic PS interfaces. PMID:17496011

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.

1983-01-01

The thermal stress models were used to test the effect of melt level on stress generation and growth velocity. The results indicate that melt level has only small effects on stresses but significant effects on growth velocity. These results are consistent with experimental growth from measured melt levels. A new low-stress design concept is being evaluated with the models. A width-limiting version of the low-stress J460 configuration was tested experimentally with results consistent with the design goals.

Silicon on Ceramic Process: Silicon Sheet Growth and Device Development for the Large-area Silicon Sheet and Cell Development Tasks of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Chapman, P. W.; Zook, J. D.; Heaps, J. D.; Pickering, C.; Grung, B. L.; Koepke, B.; Schuldt, S. B.

1979-01-01

The technical and economic feasibility of producing solar cell quality sheet silicon was investigated. It was hoped this could be done by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. Work was directed towards the solution of unique cell processing/design problems encountered with the silicon-ceramic (SOC) material due to its intimate contact with the ceramic substrate. Significant progress was demonstrated in the following areas; (1) the continuous coater succeeded in producing small-area coatings exhibiting unidirectional solidification and substatial grain size; (2) dip coater succeeded in producing thick (more than 500 micron) dendritic layers at coating speeds of 0.2-0.3 cm/sec; and (3) a standard for producing total area SOC solar cells using slotted ceramic substrates was developed.

Stress and efficiency studies in EFG

NASA Technical Reports Server (NTRS)

Kalejs, J. P.

1984-01-01

Stress and efficiency studies in EFG were carried out for silicon sheet growth. Methods were developed to quantify influence of dislocation electrical activity on bulk lifetime. A new creep law formulation for silicon stress was developed. Bulk lifetime degradation due to increase in doping levels was also examined.

Infused polymers for cell sheet release

NASA Astrophysics Data System (ADS)

Juthani, Nidhi; Howell, Caitlin; Ledoux, Haylea; Sotiri, Irini; Kelso, Susan; Kovalenko, Yevgen; Tajik, Amanda; Vu, Thy L.; Lin, Jennifer J.; Sutton, Amy; Aizenberg, Joanna

2016-05-01

Tissue engineering using whole, intact cell sheets has shown promise in many cell-based therapies. However, current systems for the growth and release of these sheets can be expensive to purchase or difficult to fabricate, hindering their widespread use. Here, we describe a new approach to cell sheet release surfaces based on silicone oil-infused polydimethylsiloxane. By coating the surfaces with a layer of fibronectin (FN), we were able to grow mesenchymal stem cells to densities comparable to those of tissue culture polystyrene controls (TCPS). Simple introduction of oil underneath an edge of the sheet caused it to separate from the substrate. Characterization of sheets post-transfer showed that they retain their FN layer and morphology, remain highly viable, and are able to grow and proliferate normally after transfer. We expect that this method of cell sheet growth and detachment may be useful for low-cost, flexible, and customizable production of cellular layers for tissue engineering.

Infused polymers for cell sheet release

PubMed Central

Juthani, Nidhi; Howell, Caitlin; Ledoux, Haylea; Sotiri, Irini; Kelso, Susan; Kovalenko, Yevgen; Tajik, Amanda; Vu, Thy L.; Lin, Jennifer J.; Sutton, Amy; Aizenberg, Joanna

2016-01-01

Tissue engineering using whole, intact cell sheets has shown promise in many cell-based therapies. However, current systems for the growth and release of these sheets can be expensive to purchase or difficult to fabricate, hindering their widespread use. Here, we describe a new approach to cell sheet release surfaces based on silicone oil-infused polydimethylsiloxane. By coating the surfaces with a layer of fibronectin (FN), we were able to grow mesenchymal stem cells to densities comparable to those of tissue culture polystyrene controls (TCPS). Simple introduction of oil underneath an edge of the sheet caused it to separate from the substrate. Characterization of sheets post-transfer showed that they retain their FN layer and morphology, remain highly viable, and are able to grow and proliferate normally after transfer. We expect that this method of cell sheet growth and detachment may be useful for low-cost, flexible, and customizable production of cellular layers for tissue engineering. PMID:27189419

Infused polymers for cell sheet release.

PubMed

Juthani, Nidhi; Howell, Caitlin; Ledoux, Haylea; Sotiri, Irini; Kelso, Susan; Kovalenko, Yevgen; Tajik, Amanda; Vu, Thy L; Lin, Jennifer J; Sutton, Amy; Aizenberg, Joanna

2016-05-18

Tissue engineering using whole, intact cell sheets has shown promise in many cell-based therapies. However, current systems for the growth and release of these sheets can be expensive to purchase or difficult to fabricate, hindering their widespread use. Here, we describe a new approach to cell sheet release surfaces based on silicone oil-infused polydimethylsiloxane. By coating the surfaces with a layer of fibronectin (FN), we were able to grow mesenchymal stem cells to densities comparable to those of tissue culture polystyrene controls (TCPS). Simple introduction of oil underneath an edge of the sheet caused it to separate from the substrate. Characterization of sheets post-transfer showed that they retain their FN layer and morphology, remain highly viable, and are able to grow and proliferate normally after transfer. We expect that this method of cell sheet growth and detachment may be useful for low-cost, flexible, and customizable production of cellular layers for tissue engineering.

A crack-closure model for predicting fatigue-crack growth under aircraft spectrum loading

NASA Technical Reports Server (NTRS)

Newman, J. C., Jr.

1981-01-01

The development and application of an analytical model of cycle crack growth is presented that includes the effects of crack closure. The model was used to correlate crack growth rates under constant amplitude loading and to predict crack growth under aircraft spectrum loading on 2219-T851 aluminum alloy sheet material. The predicted crack growth lives agreed well with experimental data. The ratio of predicted to experimental lives ranged from 0.66 to 1.48. These predictions were made using data from an ASTM E24.06.01 Round Robin.

Relative sea-level rise around East Antarctica during Oligocene glaciation

NASA Astrophysics Data System (ADS)

Stocchi, Paolo; Escutia, Carlota; Houben, Alexander J. P.; Vermeersen, Bert L. A.; Bijl, Peter K.; Brinkhuis, Henk; Deconto, Robert M.; Galeotti, Simone; Passchier, Sandra; Pollard, David; Brinkhuis, Henk; Escutia, Carlota; Klaus, Adam; Fehr, Annick; Williams, Trevor; Bendle, James A. P.; Bijl, Peter K.; Bohaty, Steven M.; Carr, Stephanie A.; Dunbar, Robert B.; Flores, Jose Abel; Gonzàlez, Jhon J.; Hayden, Travis G.; Iwai, Masao; Jimenez-Espejo, Francisco J.; Katsuki, Kota; Kong, Gee Soo; McKay, Robert M.; Nakai, Mutsumi; Olney, Matthew P.; Passchier, Sandra; Pekar, Stephen F.; Pross, Jörg; Riesselman, Christina; Röhl, Ursula; Sakai, Toyosaburo; Shrivastava, Prakash Kumar; Stickley, Catherine E.; Sugisaki, Saiko; Tauxe, Lisa; Tuo, Shouting; van de Flierdt, Tina; Welsh, Kevin; Yamane, Masako

2013-05-01

During the middle and late Eocene (~ 48-34Myr ago), the Earth's climate cooled and an ice sheet built up on Antarctica. The stepwise expansion of ice on Antarctica induced crustal deformation and gravitational perturbations around the continent. Close to the ice sheet, sea level rose despite an overall reduction in the mass of the ocean caused by the transfer of water to the ice sheet. Here we identify the crustal response to ice-sheet growth by forcing a glacial-hydro isostatic adjustment model with an Antarctic ice-sheet model. We find that the shelf areas around East Antarctica first shoaled as upper mantle material upwelled and a peripheral forebulge developed. The inner shelf subsequently subsided as lithosphere flexure extended outwards from the ice-sheet margins. Consequently the coasts experienced a progressive relative sea-level rise. Our analysis of sediment cores from the vicinity of the Antarctic ice sheet are in agreement with the spatial patterns of relative sea-level change indicated by our simulations. Our results are consistent with the suggestion that near-field processes such as local sea-level change influence the equilibrium state obtained by an ice-sheet grounding line.

"Ideal" tearing and the transition to fast reconnection in the weakly collisional MHD and EMHD regimes

NASA Astrophysics Data System (ADS)

Del Sarto, Daniele; Pucci, Fulvia; Tenerani, Anna; Velli, Marco

2016-03-01

This paper discusses the transition to fast growth of the tearing instability in thin current sheets in the collisionless limit where electron inertia drives the reconnection process. It has been previously suggested that in resistive MHD there is a natural maximum aspect ratio (ratio of sheet length and breadth to thickness) which may be reached for current sheets with a macroscopic length L, the limit being provided by the fact that the tearing mode growth time becomes of the same order as the Alfvén time calculated on the macroscopic scale. For current sheets with a smaller aspect ratio than critical the normalized growth rate tends to zero with increasing Lundquist number S, while for current sheets with an aspect ratio greater than critical the growth rate diverges with S. Here we carry out a similar analysis but with electron inertia as the term violating magnetic flux conservation: previously found scalings of critical current sheet aspect ratios with the Lundquist number are generalized to include the dependence on the ratio de2/L2, where de is the electron skin depth, and it is shown that there are limiting scalings which, as in the resistive case, result in reconnecting modes growing on ideal time scales. Finite Larmor radius effects are then included, and the rescaling argument at the basis of "ideal" reconnection is proposed to explain secondary fast reconnection regimes naturally appearing in numerical simulations of current sheet evolution.

A Novel Counter Sheet-flow Sandwich Cell Culture Device for Mammalian Cell Growth in Space

NASA Astrophysics Data System (ADS)

Sun, Shujin; Gao, Yuxin; Shu, Nanjiang; Tang, Zemei; Tao, Zulai; Long, Mian

2008-08-01

Cell culture and growth in space is crucial to understand the cellular responses under microgravity. The effects of microgravity were coupled with such environment restrictions as medium perfusion, in which the underlying mechanism has been poorly understood. In the present work, a customer-made counter sheet-flow sandwich cell culture device was developed upon a biomechanical concept from fish gill breathing. The sandwich culture unit consists of two side chambers where the medium flow is counter-directional, a central chamber where the cells are cultured, and two porous polycarbonate membranes between side and central chambers. Flow dynamics analysis revealed the symmetrical velocity profile and uniform low shear rate distribution of flowing medium inside the central culture chamber, which promotes sufficient mass transport and nutrient supply for mammalian cell growth. An on-orbit experiment performed on a recovery satellite was used to validate the availability of the device.

The use of platelet-rich fibrin combined with periodontal ligament and jaw bone mesenchymal stem cell sheets for periodontal tissue engineering

PubMed Central

Wang, Zhong-Shan; Feng, Zhi-Hong; Wu, Guo-Feng; Bai, Shi-Zhu; Dong, Yan; Chen, Fa-Ming; Zhao, Yi-Min

2016-01-01

Periodontal regeneration involves the restoration of at least three unique tissues: cementum, periodontal ligament tissue (PDL) and alveolar bone tissue. Here, we first isolated human PDL stem cells (PDLSCs) and jaw bone mesenchymal stem cells (JBMSCs). These cells were then induced to form cell sheets using an ascorbic acid-rich approach, and the cell sheet properties, including morphology, thickness and gene expression profile, were compared. Platelet-rich fibrin (PRF) derived from human venous blood was then fabricated into bioabsorbable fibrin scaffolds containing various growth factors. Finally, the in vivo potential of a cell-material construct based on PDLSC sheets, PRF scaffolds and JBMSC sheets to form periodontal tissue was assessed in a nude mouse model. In this model, PDLSC sheet/PRF/JBMSC sheet composites were placed in a simulated periodontal space comprising human treated dentin matrix (TDM) and hydroxyapatite (HA)/tricalcium phosphate (TCP) frameworks. Eight weeks after implantation, the PDLSC sheets tended to develop into PDL-like tissues, while the JBMSC sheets tended to produce predominantly bone-like tissues. In addition, the PDLSC sheet/PRF/JBMSC sheet composites generated periodontal tissue-like structures containing PDL- and bone-like tissues. Further improvements in this cell transplantation design may have the potential to provide an effective approach for future periodontal tissue regeneration. PMID:27324079

Exploring Explanations of Subglacial Bedform Sizes Using Statistical Models

PubMed Central

Kougioumtzoglou, Ioannis A.; Stokes, Chris R.; Smith, Michael J.; Clark, Chris D.; Spagnolo, Matteo S.

2016-01-01

Sediments beneath modern ice sheets exert a key control on their flow, but are largely inaccessible except through geophysics or boreholes. In contrast, palaeo-ice sheet beds are accessible, and typically characterised by numerous bedforms. However, the interaction between bedforms and ice flow is poorly constrained and it is not clear how bedform sizes might reflect ice flow conditions. To better understand this link we present a first exploration of a variety of statistical models to explain the size distribution of some common subglacial bedforms (i.e., drumlins, ribbed moraine, MSGL). By considering a range of models, constructed to reflect key aspects of the physical processes, it is possible to infer that the size distributions are most effectively explained when the dynamics of ice-water-sediment interaction associated with bedform growth is fundamentally random. A ‘stochastic instability’ (SI) model, which integrates random bedform growth and shrinking through time with exponential growth, is preferred and is consistent with other observations of palaeo-bedforms and geophysical surveys of active ice sheets. Furthermore, we give a proof-of-concept demonstration that our statistical approach can bridge the gap between geomorphological observations and physical models, directly linking measurable size-frequency parameters to properties of ice sheet flow (e.g., ice velocity). Moreover, statistically developing existing models as proposed allows quantitative predictions to be made about sizes, making the models testable; a first illustration of this is given for a hypothesised repeat geophysical survey of bedforms under active ice. Thus, we further demonstrate the potential of size-frequency distributions of subglacial bedforms to assist the elucidation of subglacial processes and better constrain ice sheet models. PMID:27458921

Preventing Freezeup in Silicon Ribbon Growth

NASA Technical Reports Server (NTRS)

Mackintosh, B.

1983-01-01

Carefully-shaped heat conductor helps control thermal gradients crucial to growth of single-crystal silicon sheets for solar cells. Ends of die through which silicon sheet is drawn as ribbon from molten silicon. Profiled heat extractor prevents ribbon ends from solidifying prematurely and breaking.

Slicing of silicon into sheet material: Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Holden, S. C.

1976-01-01

Multiblade slurry sawing is used to slice 10 cm diameter silicon ingots into wafers 0.024 cm thick using 0.050 cm of silicon per slice (0.026 cm kerf loss). Total slicing time is less than twenty hours, and 143 slices are produced simultaneously. Productivity (slice area per hour per blade) is shown as a function or blade load and thickness, and abrasive size. Finer abrasive slurries cause a reduction in slice productivity, and thin blades cause a reduction of wafer accuracy. Sawing induced surface damage is found to extend 18 microns into the wafer.

Capping Parallel β-Sheets of Acetyl(Ala)6NH2 with an Acetyl(Ala)5ProNH2 Can Arrest the Growth of the Sheet, Suggesting a Potential for Curtailing Amyloid Growth. An ONIOM and Density Functional Theory Study

PubMed Central

2015-01-01

We present ONIOM calculations using B3LYP/d95(d,p) as the high level and AM1 as the medium level on parallel β-sheets containing four strands of Ac-AAAAAA-NH2 capped with either Ac-AAPAAA-NH2 or Ac-AAAPAA-NH2. Because Pro can form H-bonds from only one side of the peptide linkage (that containing the C=O H-bond acceptor), only one of the two Pro-containing strands can favorably add to the sheet on each side. Surprisingly, when the sheet is capped with AAPAAA-NH2 at one edge, the interaction between the cap and sheet is slightly more stabilizing than that of another all Ala strand. Breaking down the interaction enthalpies into H-bonding and distortion energies shows the favorable interaction to be due to lower distortion energies in both the strand and the four-stranded sheet. Because another strand would be inhibited for attachment to the other side of the capping (Pro-containing) strand, we suggest the possible use of Pro residues in peptides designed to arrest the growth of many amyloids. PMID:24422496

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Schruben, J.

1982-01-01

The thermal stress model was used to generate the design of a low stress lid and shield configuration, which was fabricated and tested experimentally. In preliminary tests, the New Experimental Web Growth Facility performed as designed, producing web on the first run. These experiments suggested desirable design modifications in the melt level sensing system to improve further its performance, and these are being implemented.

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Schruben, J.

1982-01-01

The computer code for calculating web temperature distribution was expanded to provide a graphics output in addition to numerical and punch card output. The new code was used to examine various modifications of the J419 configuration and, on the basis of the results, a new growth geometry was designed. Additionally, several mathematically defined temperature profiles were evaluated for the effects of the free boundary (growth front) on the thermal stress generation. Experimental growth runs were made with modified J419 configurations to complement the modeling work. A modified J435 configuration was evaluated.

Towards comprehensive cell lineage reconstructions in complex organisms using light-sheet microscopy.

PubMed

Amat, Fernando; Keller, Philipp J

2013-05-01

Understanding the development of complex multicellular organisms as a function of the underlying cell behavior is one of the most fundamental goals of developmental biology. The ability to quantitatively follow cell dynamics in entire developing embryos is an indispensable step towards such a system-level understanding. In recent years, light-sheet fluorescence microscopy has emerged as a particularly promising strategy for recording the in vivo data required to realize this goal. Using light-sheet fluorescence microscopy, entire complex organisms can be rapidly imaged in three dimensions at sub-cellular resolution, achieving high temporal sampling and excellent signal-to-noise ratio without damaging the living specimen or bleaching fluorescent markers. The resulting datasets allow following individual cells in vertebrate and higher invertebrate embryos over up to several days of development. However, the complexity and size of these multi-terabyte recordings typically preclude comprehensive manual analyses. Thus, new computational approaches are required to automatically segment cell morphologies, accurately track cell identities and systematically analyze cell behavior throughout embryonic development. We review current efforts in light-sheet microscopy and bioimage informatics towards this goal, and argue that comprehensive cell lineage reconstructions are finally within reach for many key model organisms, including fruit fly, zebrafish and mouse. © 2013 The Authors Development, Growth & Differentiation © 2013 Japanese Society of Developmental Biologists.

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.

1984-01-01

The thermal models used for analyzing dendritic web growth and calculating the thermal stress were reexamined to establish the validity limits imposed by the assumptions of the models. Also, the effects of thermal conduction through the gas phase were evaluated and found to be small. New growth designs, both static and dynamic, were generated using the modeling results. Residual stress effects in dendritic web were examined. In the laboratory, new techniques for the control of temperature distributions in three dimensions were developed. A new maximum undeformed web width of 5.8 cm was achieved. A 58% increase in growth velocity of 150 micrometers thickness was achieved with dynamic hardware. The area throughput goals for transient growth of 30 and 35 sq cm/min were exceeded.

Plasma-electric field controlled growth of oriented graphene for energy storage applications

NASA Astrophysics Data System (ADS)

Ghosh, Subrata; Polaki, S. R.; Kamruddin, M.; Jeong, Sang Mun; (Ken Ostrikov, Kostya

2018-04-01

It is well known that graphene grows as flat sheets aligned with the growth substrate. Oriented graphene structures typically normal to the substrate have recently attracted major attention. Most often, the normal orientation is achieved in a plasma-assisted growth and is believed to be due to the plasma-induced in-built electric field, which is usually oriented normal to the substrate. This work focuses on the effect of an in-built electric field on the growth direction, morphology, interconnectedness, structural properties and also the supercapacitor performance of various configurations of graphene structures and reveals the unique dependence of these features on the electric field orientation. It is shown that tilting of growth substrates from parallel to the normal direction with respect to the direction of in-built plasma electric field leads to the morphological transitions from horizontal graphene layers, to oriented individual graphene sheets and then interconnected 3D networks of oriented graphene sheets. The revealed transition of the growth orientation leads to a change in structural properties, wetting nature, types of defect in graphitic structures and also affects their charge storage capacity when used as supercapacitor electrodes. This simple and versatile approach opens new opportunities for the production of potentially large batches of differently oriented and structured graphene sheets in one production run.

Slicing of Silicon into Sheet Material. Silicon Sheet Growth Development for the Large Area Silicon Sheet Task of the Low Cost Solar Array Project

NASA Technical Reports Server (NTRS)

Fleming, J. R.; Holden, S. C.; Wolfson, R. G.

1979-01-01

The use of multiblade slurry sawing to produce silicon wafers from ingots was investigated. The commercially available state of the art process was improved by 20% in terms of area of silicon wafers produced from an ingot. The process was improved 34% on an experimental basis. Economic analyses presented show that further improvements are necessary to approach the desired wafer costs, mostly reduction in expendable materials costs. Tests which indicate that such reduction is possible are included, although demonstration of such reduction was not completed. A new, large capacity saw was designed and tested. Performance comparable with current equipment (in terms of number of wafers/cm) was demonstrated.

Dip coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Heaps, J. D.; Maciolek, R. B.; Zook, J. D.; Harrison, W. B.; Scott, M. W.; Hendrickson, G.; Wolner, H. A.; Nelson, L. D.; Schuller, T. L.; Peterson, A. A.

1976-01-01

The technical and economic feasibility of producing solar cell quality sheet silicon by dip-coating one surface of carbonized ceramic substrates with a thin layer of large grain polycrystalline silicon was investigated. The dip-coating methods studied were directed toward a minimum cost process with the ultimate objective of producing solar cells with a conversion efficiency of 10% or greater. The technique shows excellent promise for low cost, labor-saving, scale-up potentialities and would provide an end product of sheet silicon with a rigid and strong supportive backing. An experimental dip-coating facility was designed and constructed, several substrates were successfully dip-coated with areas as large as 25 sq cm and thicknesses of 12 micron to 250 micron. There appears to be no serious limitation on the area of a substrate that could be coated. Of the various substrate materials dip-coated, mullite appears to best satisfy the requirement of the program. An inexpensive process was developed for producing mullite in the desired geometry.

Ice core evidence for extensive melting of the greenland ice sheet in the last interglacial.

PubMed

Koerner, R M

1989-05-26

Evidence from ice at the bottom of ice cores from the Canadian Arctic Islands and Camp Century and Dye-3 in Greenland suggests that the Greenland ice sheet melted extensively or completely during the last interglacial period more than 100 ka (thousand years ago), in contrast to earlier interpretations. The presence of dirt particles in the basal ice has previously been thought to indicate that the base of the ice sheets had melted and that the evidence for the time of original growth of these ice masses had been destroyed. However, the particles most likely blew onto the ice when the dimensions of the ice caps and ice sheets were much smaller. Ice texture, gas content, and other evidence also suggest that the basal ice at each drill site is superimposed ice, a type of ice typical of the early growth stages of an ice cap or ice sheet. If the present-day ice masses began their growth during the last interglacial, the ice sheet from the earlier (Illinoian) glacial period must have competely or largely melted during the early part of the same interglacial period. If such melting did occur, the 6-meter higher-than-present sea level during the Sangamon cannot be attributed to disintegration of the West Antarctic ice sheet, as has been suggested.

High-efficiency cell concepts on low-cost silicon sheets

NASA Technical Reports Server (NTRS)

Bell, R. O.; Ravi, K. V.

1985-01-01

The limitations on sheet growth material in terms of the defect structure and minority carrier lifetime are discussed. The effect of various defects on performance are estimated. Given these limitations designs for a sheet growth cell that will make the best of the material characteristics are proposed. Achievement of optimum synergy between base material quality and device processing variables is proposed. A strong coupling exists between material quality and the variables during crystal growth, and device processing variables. Two objectives are outlined: (1) optimization of the coupling for maximum performance at minimal cost; and (2) decoupling of materials from processing by improvement in base material quality to make it less sensitive to processing variables.

Silicon web process development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hill, F. E.; Skutch, M. E.; Driggers, J. M.; Hopkins, R. H.

1980-01-01

A barrier crucible design which consistently maintains melt stability over long periods of time was successfully tested and used in long growth runs. The pellet feeder for melt replenishment was operated continuously for growth runs of up to 17 hours. The liquid level sensor comprising a laser/sensor system was operated, performed well, and meets the requirements for maintaining liquid level height during growth and melt replenishment. An automated feedback loop connecting the feed mechanism and the liquid level sensing system was designed and constructed and operated successfully for 3.5 hours demonstrating the feasibility of semi-automated dendritic web growth. The sensitivity of the cost of sheet, to variations in capital equipment cost and recycling dendrites was calculated and it was shown that these factors have relatively little impact on sheet cost. Dendrites from web which had gone all the way through the solar cell fabrication process, when melted and grown into web, produce crystals which show no degradation in cell efficiency. Material quality remains high and cells made from web grown at the start, during, and the end of a run from a replenished melt show comparable efficiencies.

Experimental Aspects of the Study of Stress Generating Mechanisms in Silicon Sheet Growth

NASA Technical Reports Server (NTRS)

Kaleja, J. P.; Bell, R. O.

1984-01-01

Stress analysis on silicon sheet grown at high speeds of the growth behavior and defect structure of 10 cm wide ribbon produced by the EFG technique was examined. The ribbon temperature field, the high temperature creep response of silicon, and approaches to measurement of the residual stress are investigated.

Geometry of thin liquid sheet flows

NASA Technical Reports Server (NTRS)

Chubb, Donald L.; Calfo, Frederick D.; Mcconley, Marc W.; Mcmaster, Matthew S.; Afjeh, Abdollah A.

1994-01-01

Incompresible, thin sheet flows have been of research interest for many years. Those studies were mainly concerned with the stability of the flow in a surrounding gas. Squire was the first to carry out a linear, invicid stability analysis of sheet flow in air and compare the results with experiment. Dombrowski and Fraser did an experimental study of the disintegration of sheet flows using several viscous liquids. They also detected the formulation of holes in their sheet flows. Hagerty and Shea carried out an inviscid stability analysis and calculated growth rates with experimental values. They compared their calculated growth rates with experimental values. Taylor studied extensively the stability of thin liquid sheets both theoretically and experimentally. He showed that thin sheets in a vacuum are stable. Brown experimentally investigated thin liquid sheet flows as a method of application of thin films. Clark and Dumbrowski carried out second-order stability analysis for invicid sheet flows. Lin introduced viscosity into the linear stability analysis of thin sheet flows in a vacuum. Mansour and Chigier conducted an experimental study of the breakup of a sheet flow surrounded by high-speed air. Lin et al. did a linear stability analysis that included viscosity and a surrounding gas. Rangel and Sirignano carried out both a linear and nonlinear invisid stability analysis that applies for any density ratio between the sheet liquid and the surrounding gas. Now there is renewed interest in sheet flows because of their possible application as low mass radiating surfaces. The objective of this study is to investigate the fluid dynamics of sheet flows that are of interest for a space radiator system. Analytical expressions that govern the sheet geometry are compared with experimental results. Since a space radiator will operate in a vacuum, the analysis does not include any drag force on the sheet flow.

Development of low-cost silicon crystal growth techniques for terrestrial photovoltaic solar energy conversion

NASA Technical Reports Server (NTRS)

Zoutendyk, J. A.

1976-01-01

Because of the growing need for new sources of electrical energy, photovoltaic solar energy conversion is being developed. Photovoltaic devices are now being produced mainly from silicon wafers obtained from the slicing and polishing of cylindrically shaped single crystal ingots. Inherently high-cost processes now being used must either be eliminated or modified to provide low-cost crystalline silicon. Basic to this pursuit is the development of new or modified methods of crystal growth and, if necessary, crystal cutting. If silicon could be grown in a form requiring no cutting, a significant cost saving would potentially be realized. Therefore, several techniques for growth in the form of ribbons or sheets are being explored. In addition, novel techniques for low-cost ingot growth and cutting are under investigation.

Large area sheet task: Advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Schruben, J.

1981-01-01

The growth of silicon dendritic web for photovoltaic applications was investigated. The application of a thermal model for calculating buckling stresses as a function of temperature profile in the web is discussed. Lid and shield concepts were evaluated to provide the data base for enhancing growth velocity. An experimental web growth machine which embodies in one unit the mechanical and electronic features developed in previous work was developed. In addition, evaluation of a melt level control system was begun, along with preliminary tests of an elongated crucible design. The economic analysis was also updated to incorporate some minor cost changes. The initial applications of the thermal model to a specific configuration gave results consistent with experimental observation in terms of the initiation of buckling vs. width for a given crystal thickness.

The Growth of Instabilities in Annular Liquid Sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duke, Daniel J.; Honnery, Damon R; Soria, Julio

An annular liquid sheet surrounded by parallel co-flowing gas is an effective atomiser. However, the initial instabilities which determine the primary break-up of the liquid sheet are not well understood. Lack of agreement on the influence of the boundary conditions and the non-dimension scaling of the initial instability persists between theoretical stability analyses and experiments. To address this matter, we have undertaken an experimental parametric study of an aerodynamically-driven, non-swirling annular water sheet. The effects of sheet thickness, inner and outer gas-liquid momentum ratio were investigated over an order of magnitude variation in Reynolds and Weber number. From high-speed imagemore » correlation measurements in the near-nozzle region, we propose new empirical correlations for the frequency of the instability as a function of the total gas-liquid momentum ratio, with good non-dimensional collapse. From analysis of the instability velocity probability densities, we find two persistent and distinct superimposed instabilities with different growth rates. The first is a short-lived, rapidly saturating sawtooth-like instability. The second is a slower-growing stochastic instability which persists through the break-up of the sheet. The presence of multiple instabilities whose growth rates do not strongly correlate with the shear velocities may explain some of the discrepancies between experiments and stability analyses.« less

Large-area sheet task: Advanced dendritic-web-growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Schruben, J.

1983-01-01

Thermally generated stresses in the growing web crystal were reduced. These stresses, which if too high cause the ribbon to degenerate, were reduced by a factor of three, resulting in the demonstrated growth of high-quality web crystals to widths of 5.4 cm. This progress was brought about chiefly by the application of thermal models to the development of low-stress growth configurations. A new temperature model was developed which can analyze the thermal effects of much more complex lid and top shield configurations than was possible with the old lumped shield model. Growth experiments which supplied input data such as actual shield temperature and melt levels were used to verify the modeling results. Desirable modifications in the melt level-sensing circuitry were made in the new experimental web growth furnace, and this furnace has been used to carry out growth experiments under steady-state conditions. New growth configurations were tested in long growth runs at Westinghouse AESD which produced wider, lower stress and higher quality web crystals than designs previously used.

Reconstructing the last Irish Ice Sheet 2: a geomorphologically-driven model of ice sheet growth, retreat and dynamics

NASA Astrophysics Data System (ADS)

Greenwood, Sarah L.; Clark, Chris D.

2009-12-01

The ice sheet that once covered Ireland has a long history of investigation. Much prior work focussed on localised evidence-based reconstructions and ice-marginal dynamics and chronologies, with less attention paid to an ice sheet wide view of the first order properties of the ice sheet: centres of mass, ice divide structure, ice flow geometry and behaviour and changes thereof. In this paper we focus on the latter aspect and use our new, countrywide glacial geomorphological mapping of the Irish landscape (>39 000 landforms), and our analysis of the palaeo-glaciological significance of observed landform assemblages (article Part 1), to build an ice sheet reconstruction yielding these fundamental ice sheet properties. We present a seven stage model of ice sheet evolution, from initiation to demise, in the form of palaeo-geographic maps. An early incursion of ice from Scotland likely coalesced with local ice caps and spread in a south-westerly direction 200 km across Ireland. A semi-independent Irish Ice Sheet was then established during ice sheet growth, with a branching ice divide structure whose main axis migrated up to 140 km from the west coast towards the east. Ice stream systems converging on Donegal Bay in the west and funnelling through the North Channel and Irish Sea Basin in the east emerge as major flow components of the maximum stages of glaciation. Ice cover is reconstructed as extending to the continental shelf break. The Irish Ice Sheet became autonomous (i.e. separate from the British Ice Sheet) during deglaciation and fragmented into multiple ice masses, each decaying towards the west. Final sites of demise were likely over the mountains of Donegal, Leitrim and Connemara. Patterns of growth and decay of the ice sheet are shown to be radically different: asynchronous and asymmetric in both spatial and temporal domains. We implicate collapse of the ice stream system in the North Channel - Irish Sea Basin in driving such asymmetry, since rapid collapse would sever the ties between the British and Irish Ice Sheets and drive flow configuration changes in response. Enhanced calving and flow acceleration in response to rising relative sea level is speculated to have undermined the integrity of the ice stream system, precipitating its collapse and driving the reconstructed pattern of ice sheet evolution.

Laser-zone Growth in a Ribbon-to-ribbon (RTR) Process Silicon Sheet Growth Development for the Large Area Silicon Sheet Task of the Low Cost Solar Array Project

NASA Technical Reports Server (NTRS)

Baghdadi, A.; Gurtler, R. W.; Legge, R.; Sopori, B.; Rice, M. J.; Ellis, R. J.

1979-01-01

A technique for growing limited-length ribbons continually was demonstrated. This Rigid Edge technique can be used to recrystallize about 95% of the polyribbon feedstock. A major advantage of this method is that only a single, constant length silicon ribbon is handled throughout the entire process sequence; this may be accomplished using cassettes similar to those presently in use for processing Czochralski waters. Thus a transition from Cz to ribbon technology can be smoothly affected. The maximum size being considered, 3 inches x 24 inches, is half a square foot, and will generate 6 watts for 12% efficiency at 1 sun. Silicon dioxide has been demonstrated as an effective, practical diffusion barrier for use during the polyribbon formation.

On the Reconstruction of Palaeo-Ice Sheets: Recent Advances and Future Challenges

NASA Technical Reports Server (NTRS)

Stokes, Chris R.; Tarasov, Lev; Blomdin, Robin; Cronin, Thomas M.; Fisher, Timothy G.; Gyllencreutz, Richard; Hattestrand, Clas; Heyman, Jacob; Hindmarsh, Richard C. A.; Hughes, Anna L. C.;

On the reconstruction of palaeo-ice sheets: Recent advances and future challenges

USGS Publications Warehouse

Stokes, Chris R.; Tarasov, Lev; Blomdin, Robin; Cronin, Thomas M.; Fisher, Timothy G.; Gyllencreutz, Richard; Hattestrand, Clas; Heyman, Jakob; Hindmarsh, Richard C. A.; Hughes, Anna L. C.; Jakobsson, Martin; Kirchner, Nina; Livingstone, Stephen J.; Margold, Martin; Murton, Julian B.; Noormets, Riko; Peltier, W. Richard; Peteet, Dorothy M.; Piper, David J. W.; Preusser, Frank; Renssen, Hans; Roberts, David H.; Roche, Didier M.; Saint-Ange, Francky; Stroeven, Arjen P.; Teller, James T.

2015-01-01

Reconstructing the growth and decay of palaeo-ice sheets is critical to understanding mechanisms of global climate change and associated sea-level fluctuations in the past, present and future. The significance of palaeo-ice sheets is further underlined by the broad range of disciplines concerned with reconstructing their behaviour, many of which have undergone a rapid expansion since the 1980s. In particular, there has been a major increase in the size and qualitative diversity of empirical data used to reconstruct and date ice sheets, and major improvements in our ability to simulate their dynamics in numerical ice sheet models. These developments have made it increasingly necessary to forge interdisciplinary links between sub-disciplines and to link numerical modelling with observations and dating of proxy records. The aim of this paper is to evaluate recent developments in the methods used to reconstruct ice sheets and outline some key challenges that remain, with an emphasis on how future work might integrate terrestrial and marine evidence together with numerical modelling. Our focus is on pan-ice sheet reconstructions of the last deglaciation, but regional case studies are used to illustrate methodological achievements, challenges and opportunities. Whilst various disciplines have made important progress in our understanding of ice-sheet dynamics, it is clear that data-model integration remains under-used, and that uncertainties remain poorly quantified in both empirically-based and numerical ice-sheet reconstructions. The representation of past climate will continue to be the largest source of uncertainty for numerical modelling. As such, palaeo-observations are critical to constrain and validate modelling. State-of-the-art numerical models will continue to improve both in model resolution and in the breadth of inclusion of relevant processes, thereby enabling more accurate and more direct comparison with the increasing range of palaeo-observations. Thus, the capability is developing to use all relevant palaeo-records to more strongly constrain deglacial (and to a lesser extent pre-LGM) ice sheet evolution. In working towards that goal, the accurate representation of uncertainties is required for both constraint data and model outputs. Close cooperation between modelling and data-gathering communities is essential to ensure this capability is realised and continues to progress.

Nucleation and growth of electrodeposited Mn oxide rods for supercapacitor electrodes

NASA Astrophysics Data System (ADS)

Clark, Michael; Ivey, Douglas G.

2015-09-01

The nucleation and growth of electrodeposited Mn oxide rods has been investigated by preparing deposits on Au coated Si at varying deposition times between 0.5 s and 10 min. The deposits were investigated using high resolution scanning and transmission electron microscopy. A model for the nucleation and growth of Mn oxide rods has been proposed. Nucleation begins as thin sheets along Au grain boundaries and triple points. As these nucleation sites are consumed, nucleation spreads across the grains. Nucleation of sheets in close proximity causes agglomeration and the formation of rounded particles. Some of these rounded particles then accelerate in growth, initially in all directions and then primarily in the direction normal to the sample surface. Accelerated growth normal to the sample surface leads to the formation of rods. As rods grow, the growth of other particles accelerates and they become rods themselves. Eventually the entire sample surface is covered with rods 15-20 μm long and about 2 μm wide. The sheet-like morphology of the deposits is retained at all stages of deposition. Electron diffraction analysis of 3 s and 6 s deposits shows that the sheets are initially amorphous and then begin to crystallize into a cubic spinel Mn3O4 crystal structure. High resolution imaging of the 6 s sample shows small crystalline regions (˜5 nm in size) within an amorphous matrix.

Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy.

PubMed

Costa, Marina; Cerqueira, Mariana T; Santos, Tírcia C; Sampaio-Marques, Belém; Ludovico, Paula; Marques, Alexandra P; Pirraco, Rogério P; Reis, Rui L

2017-06-01

Current vascularization strategies for Tissue Engineering constructs, in particular cell sheet-based, are limited by time-consuming and expensive endothelial cell isolation and/or by the complexity of using extrinsic growth factors. Herein, we propose an alternative strategy using angiogenic cell sheets (CS) obtained from the stromal vascular fraction (SVF) of adipose tissue that can be incorporated into more complex constructs. Cells from the SVF were cultured in normoxic and hypoxic conditions for up to 8days in the absence of extrinsic growth factors. Immunocytochemistry against CD31 and CD146 revealed spontaneous organization in capillary-like structures, more complex after hypoxic conditioning. Inhibition of HIF-1α pathway hindered capillary-like structure formation in SVF cells cultured in hypoxia, suggesting a role of HIF-1α. Moreover, hypoxic SVF cells showed a trend for increased secretion of angiogenic factors, which was reflected in increased network formation by endothelial cells cultured on matrigel using that conditioned medium. In vivo implantation of SVF CS in a mouse hind limb ischemia model revealed that hypoxia-conditioned CS led to improved restoration of blood flow. Both in vitro and in vivo data suggest that SVF CS can be used as simple and cost-efficient tools to promote functional vascularization of TE constructs. Neovascularization after implantation is a major obstacle for producing clinically viable cell sheet-based tissue engineered constructs. Strategies using endothelial cells and extrinsic angiogenic growth factors are expensive and time consuming and may raise concerns of tumorigenicity. In this manuscript, we describe a simplified approach using angiogenic cell sheets fabricated from the stromal vascular fraction of adipose tissue. The strong angiogenic behavior of these cell sheets, achieved without the use of external growth factors, was further stimulated by low oxygen culture. When implanted in an in vivo model of hind limb ischemia, the angiogenic cell sheets contributed to blood flux recovery. These cell sheets can therefore be used as a straightforward tool to increase the neovascularization of cell sheet-based thick constructs. Copyright © 2017. Published by Elsevier Ltd.

Silk Film Topography Directs Collective Epithelial Cell Migration

PubMed Central

Rosenblatt, Mark I.

2012-01-01

The following study provides new insight into how surface topography dictates directed collective epithelial cell sheet growth through the guidance of individual cell movement. Collective cell behavior of migrating human corneal limbal-epithelial cell sheets were studied on highly biocompatible flat and micro-patterned silk film surfaces. The silk film edge topography guided the migratory direction of individual cells making up the collective epithelial sheet, which resulted in a 75% increase in total culture elongation. This was due to a 3-fold decrease in cell sheet migration rate efficiency for movement perpendicular to the topography edge. Individual cell migration direction is preferred in the parallel approach to the edge topography where localization of cytoskeletal proteins to the topography’s edge region is reduced, which results in the directed growth of the collective epithelial sheet. Findings indicate customized biomaterial surfaces may be created to direct both the migration rate and direction of tissue epithelialization. PMID:23185573

Slicing of silicon into sheet material. Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Holden, S. C.; Fleming, J. R.

1978-01-01

Fabrication of a prototype large capacity multiple blade slurry saw is considered. Design of the bladehead which will tension up to 1000 blades, and cut a 45 cm long silicon ingot as large as 12 cm in diameter is given. The large blade tensioning force of 270,000 kg is applied through two bolts acting on a pair of scissor toggles, significantly reducing operator set-up time. Tests with an upside-down cutting technique resulted in 100% wafering yields and the highest wafer accuracy yet experienced with MS slicing. Variations in oil and abrasives resulted only in degraded slicing results. A technique of continuous abrasive slurry separation to remove silicon debris is described.

Large area sheet task: Advanced Dendritic Web Growth Development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Schruben, J.

1981-01-01

A melt level control system was implemented to provide stepless silicon feed rates from zero to rates exactly matching the silicon consumed during web growth. Bench tests of the unit were successfully completed and the system mounted in a web furnace for operational verification. Tests of long term temperature drift correction techniques were made; web width monitoring seems most appropriate for feedback purposes. A system to program the initiation of the web growth cycle was successfully tested. A low cost temperature controller was tested which functions as well as units four times as expensive.

Large-area sheet task advanced dendritic web growth development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.; Meier, D.; Schruben, J.

1982-01-01

The "discrete shield' temperature model was completed and verified. Modifications to the J419 low stress configuration were tested experimentally to evaluate effects on growth speed. A composite lid and shield configuration combining the low stress features of the J419 with the width limiting characteristics of the J98M3 was fabricated and tested in the N-furnace. Several long crystals were grown with width limited to about 3.3 cm and with melt replenishment, although the configuration is not yet optimized for steady state growth.

Microphase Separation Controlled Beta Sheet Crystallization Kinetics in Silk Fibroin Protein.

NASA Astrophysics Data System (ADS)

Hu, Xiao; Lu, Qiang; Kaplan, David; Cebe, Peggy

2009-03-01

We investigate the mechanism of isothermal crystallization kinetics of beta-sheet crystals in silk multiblock fibrous proteins. The Avrami analysis kinetic theory, for studies of synthetic polymer crystal growth, is for the first time extended to investigate protein self-assembly in beta-sheet rich Bombyx mori silk fibroin samples, using time-resolved Fourier transform infrared spectroscopy, differential scanning calorimetry and synchrotron real-time wide-angle X-ray scattering. Results indicate formation of beta sheet crystals in silk proteins is different from the 3-D spherulitic crystal growth found in synthetic homopolymers. Observations by scanning electron microscopy support the view that the protein structures vary during the different stages of crystal growth, and show a microphase separation pattern after chymotrypsin enzyme biodegradation. We present a model to explain the crystallization of the multiblock silk fibroin protein, by analogy to synthetic block copolymers. This model could be widely applicable in other proteins with multiblock (i.e., crystallizable and non-crystallizable) domains.

A recipe for designing water-soluble, beta-sheet-forming peptides.

PubMed Central

Mayo, K. H.; Ilyina, E.; Park, H.

1996-01-01

Based on observations of solubility and folding properties of peptide 33-mers derived from the beta-sheet domains of platelet factor-4 (PF4), interleukin-8 (IL-8), and growth related protein (Gro-alpha), as well as other beta-sheet-forming peptides, general guidelines have been developed to aid in the design of water soluble, self-association-induced beta-sheet-forming peptides. CD, 1H-NMR, and pulsed field gradient NMR self-diffusion measurements have been used to assess the degree of folding and state of aggregation. PF4 peptide forms native-like beta-sheet tetramers and is sparingly soluble above pH 6. IL-8 peptide is insoluble between pH 4.5 and pH 7.5, yet forms stable, native-like beta-sheet dimers at higher pH. Gro-alpha peptide is soluble at all pH values, yet displays no discernable beta-sheet structure even when diffusion data indicate dimer-tetramer aggregation. A recipe used in the de novo design of water-soluble beta-sheet-forming peptides calls for the peptide to contain 40-50% hydrophobic residues, usually aliphatic ones (I, L, V, A, M) (appropriately paired and mostly but not always alternating with polar residues in the sheet sequence), a positively charged (K, R) to negatively charged (E, D) residue ratio between 4/2 and 6/2, and a noncharged polar residue (N, Q, T, S) composition of about 20% or less. Results on four de novo designed, 33-residue peptides are presented supporting this approach. Under near physiologic conditions, all four peptides are soluble, form beta-sheet structures to varying degrees, and self-associate. One peptide folds as a stable, compact beta-sheet tetramer, whereas the others are transient beta-sheet-containing aggregates. PMID:8819163

Buckling and stretching of thin viscous sheets

NASA Astrophysics Data System (ADS)

O'Kiely, Doireann; Breward, Chris; Griffiths, Ian; Howell, Peter; Lange, Ulrich

2016-11-01

Thin glass sheets are used in smartphone, battery and semiconductor technology, and may be manufactured by producing a relatively thick glass slab and subsequently redrawing it to a required thickness. The resulting sheets commonly possess undesired centerline ripples and thick edges. We present a mathematical model in which a viscous sheet undergoes redraw in the direction of gravity, and show that, in a sufficiently strong gravitational field, buckling is driven by compression in a region near the bottom of the sheet, and limited by viscous resistance to stretching of the sheet. We use asymptotic analysis in the thin-sheet, low-Reynolds-number limit to determine the centerline profile and growth rate of such a viscous sheet.

Technical progress in silicon sheet growth under DOE/JPL FSA program, 1975-1986

NASA Technical Reports Server (NTRS)

Kalejs, J. P.

1986-01-01

The technical progress made in the Silicon Sheet Growth Program during its 11 years was reviewed. At present, in 1986, only two of the original 9 techniques have survived to the start-up, pilot-plant stage in industry. These two techniques are the edge-defined, film-fed growth (EFG) technique that produces closed shape polygons, and the WEB dendritic technique that produces single ribbons. Both the status and future concerns of the EFG and WEB techniques were discussed.

Magnetotail dynamics under isobaric constraints

NASA Technical Reports Server (NTRS)

Birn, Joachim; Schindler, Karl; Janicke, Lutz; Hesse, Michael

1994-01-01

Using linear theory and nonlinear MHD simulations, we investigate the resistive and ideal MHD stability of two-dimensional plasma configurations under the isobaric constraint dP/dt = 0, which in ideal MHD is equivalent to conserving the pressure function P = P(A), where A denotes the magnetic flux. This constraint is satisfied for incompressible modes, such as Alfven waves, and for systems undergoing energy losses. The linear stability analysis leads to a Schroedinger equation, which can be investigated by standard quantum mechanics procedures. We present an application to a typical stretched magnetotail configuration. For a one-dimensional sheet equilibrium characteristic properties of tearing instability are rediscovered. However, the maximum growth rate scales with the 1/7 power of the resistivity, which implies much faster growth than for the standard tearing mode (assuming that the resistivity is small). The same basic eigen-mode is found also for weakly two-dimensional equilibria, even in the ideal MHD limit. In this case the growth rate scales with the 1/4 power of the normal magnetic field. The results of the linear stability analysis are confirmed qualitatively by nonlinear dynamic MHD simulations. These results suggest the interesting possibility that substorm onset, or the thinning in the late growth phase, is caused by the release of a thermodynamic constraint without the (immediate) necessity of releasing the ideal MHD constraint. In the nonlinear regime the resistive and ideal developments differ in that the ideal mode does not lead to neutral line formation without the further release of the ideal MHD constraint; instead a thin current sheet forms. The isobaric constraint is critically discussed. Under perhaps more realistic adiabatic conditions the ideal mode appears to be stable but could be driven by external perturbations and thus generate the thin current sheet in the late growth phase, before a nonideal instability sets in.

InN thin-film transistors fabricated on polymer sheets using pulsed sputtering deposition at room temperature

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lye, Khe Shin; Kobayashi, Atsushi; Ueno, Kohei

Indium nitride (InN) is potentially suitable for the fabrication of high performance thin-film transistors (TFTs) because of its high electron mobility and peak electron velocity. However, InN is usually grown using a high temperature growth process, which is incompatible with large-area and lightweight TFT substrates. In this study, we report on the room temperature growth of InN films on flexible polyimide sheets using pulsed sputtering deposition. In addition, we report on the fabrication of InN-based TFTs on flexible polyimide sheets and the operation of these devices.

Graphene oxide sheets-based platform for induced pluripotent stem cells culture: toxicity, adherence, growth and application

NASA Astrophysics Data System (ADS)

Durán, Marcela; Andrade, Patricia F.; Durán, Nelson; Luzo, Angela C. M.; Fávaro, Wagner J.

2015-05-01

It was prepared the graphene oxide (GO) sheets by suspension of GO in ultrapure deionized water or in Pluronic F-68 using a ultrasonicator bath. Total characterization of GO sheets was carried out. The results on suspension of GO in water showed excellent growth and cell adhesion. GO/Pluronic F-68 platform for the growth and adhesion of adipose-derived stem cells (ASCs) that exhibits excellent properties for these processes. GO in water suspension exhibited an inhibition of the cell growth over 5 μg/mL In vivo study with GO suspended in water (100 μg/mL) on Fisher 344 rats via i.p. administration showed low toxicity. Despite GO particle accumulates in the intraperitoneal cavity, this fact did not interfere with the final absorption of GO. The AST (aspartate aminotransferase) and ALT (alanine aminotransferase) levels (liver function) did not differ statistically in all experimental groups. Also, creatinine and urea levels (renal function) did not differ statistically in all experimental groups. Taking together, the data suggest the great potential of graphene oxide sheets as platform to ACSs, as well as, new material for treatment several urological diseases.

Proceedings of the 24th Project Integration Meeting

NASA Technical Reports Server (NTRS)

Tustin, D.

1984-01-01

Progress made by the Flat-Plate Solar Array Project is described. Reports on silicon sheet growth and characterization, silicon material, process development, high-efficiency cells, environmental isolation, engineering sciences, and reliability physics are presented along with copies of visual presentations made at the 24th Project Integration Meeting.

Active control: an investigation method for combustion instabilities

NASA Astrophysics Data System (ADS)

Poinsot, T.; Yip, B.; Veynante, D.; Trouvé, A.; Samaniego, J. M.; Candel, S.

1992-07-01

Closed-loop active control methods and their application to combustion instabilities are discussed. In these methods the instability development is impeded with a feedback control loop: the signal provided by a sensor monitoring the flame or pressure oscillations is processed and sent back to actuators mounted on the combustor or on the feeding system. Different active control systems tested on a non-premixed multiple-flame turbulent combustor are described. These systems can suppress all unstable plane modes of oscillation (i.e. low frequency modes). The active instability control (AIC) also constitutes an original and powerful technique for studies of mechanisms leading to instability or resulting from the instability. Two basic applications of this kind are described. In the first case the flame is initially controlled with AIC, the feedback loop is then switched off and the growth of the instability is analysed through high speed Schlieren cinematography and simultaneous sound pressure and reaction rate measurements. Three phases are identified during th growth of the oscillations: (1) a linear phase where acoustic waves induce a flapping motion of the flame sheets without interaction between sheets, (2) a modulation phase, where flame sheets interact randomly and (3) a nonlinear phase where the flame sheets are broken and a limit cycle is reached. In the second case we investigate different types of flame extinctions associated with combustion instability. It is shown that pressure oscillations may lead to partial or total extinctions. Extinctions occur in various forms but usually follow a rapid growth of pressure oscillations. The flame is extinguished during the modulation phase observed in the initiation experiments. In these studies devoted to transient instability phenomena, the control system constitutes a unique investigation tool because it is difficult to obtain the same information by other means. Implications for modelling and prediction of combustion instabilities are discussed.

Enhanced ice sheet growth in Eurasia owing to adjacent ice-dammed lakes.

PubMed

Krinner, G; Mangerud, J; Jakobsson, M; Crucifix, M; Ritz, C; Svendsen, J I

2004-01-29

Large proglacial lakes cool regional summer climate because of their large heat capacity, and have been shown to modify precipitation through mesoscale atmospheric feedbacks, as in the case of Lake Agassiz. Several large ice-dammed lakes, with a combined area twice that of the Caspian Sea, were formed in northern Eurasia about 90,000 years ago, during the last glacial period when an ice sheet centred over the Barents and Kara seas blocked the large northbound Russian rivers. Here we present high-resolution simulations with an atmospheric general circulation model that explicitly simulates the surface mass balance of the ice sheet. We show that the main influence of the Eurasian proglacial lakes was a significant reduction of ice sheet melting at the southern margin of the Barents-Kara ice sheet through strong regional summer cooling over large parts of Russia. In our simulations, the summer melt reduction clearly outweighs lake-induced decreases in moisture and hence snowfall, such as has been reported earlier for Lake Agassiz. We conclude that the summer cooling mechanism from proglacial lakes accelerated ice sheet growth and delayed ice sheet decay in Eurasia and probably also in North America.

Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel.

PubMed

Ishida, Sumire; Tanaka, Ryosuke; Yamaguchi, Naoya; Ogata, Genki; Mizutani, Takeomi; Kawabata, Kazushige; Haga, Hisashi

2014-01-01

Lumen formation is important for morphogenesis; however, an unanswered question is whether it involves the collective migration of epithelial cells. Here, using a collagen gel overlay culture method, we show that Madin-Darby canine kidney cells migrated collectively and formed a luminal structure in a collagen gel. Immediately after the collagen gel overlay, an epithelial sheet folded from the periphery, migrated inwardly, and formed a luminal structure. The inhibition of integrin-β1 or Rac1 activity decreased the migration rate of the peripheral cells after the sheets folded. Moreover, lumen formation was perturbed by disruption of apical-basolateral polarity induced by transforming growth factor-β1. These results indicate that cell migration and cell polarity play an important role in folding. To further explore epithelial sheet folding, we developed a computer-simulated mechanical model based on the rigidity of the extracellular matrix. It indicated a soft substrate is required for the folding movement.

Effect of Thermomechanical Processing on Texture and Superelasticity in Fe-Ni-Co-Al-Ti-B Alloy

NASA Astrophysics Data System (ADS)

Lee, Doyup; Omori, Toshihiro; Han, Kwangsik; Hayakawa, Yasuyuki; Kainuma, Ryosuke

2018-03-01

The texture and superelasticity were investigated in austenitic Fe-Ni-Co-Al-Ti-B alloy with various reduction ratios of cold rolling and heating ratios in annealing. The rolled sheets show the {110} <112> deformation texture at a reduction ratio higher than 80%, while the texture hardly changes in the primary recrystallization at 1000 °C. The β (B2) precipitates inhibit the grain growth at this temperature, but they dissolve during heating, and secondary recrystallization occurs due to decreased pinning force at temperatures higher than 1100 °C, resulting in texture change to {210} <001> . The recrystallization texture is more strongly developed when the reduction ratio and heating rate are high and slow, respectively. The 90% cold-rolled and slowly heated sheet shows the recrystallization texture and high fraction of low-angle boundaries. As a result, ductility and superelasticity can be drastically improved in the 90% cold-rolled sheet, although superelasticity was previously obtained only in thin sheets with 98.5% reduction.

Graphene growth process modeling: a physical-statistical approach

NASA Astrophysics Data System (ADS)

Wu, Jian; Huang, Qiang

2014-09-01

As a zero-band semiconductor, graphene is an attractive material for a wide variety of applications such as optoelectronics. Among various techniques developed for graphene synthesis, chemical vapor deposition on copper foils shows high potential for producing few-layer and large-area graphene. Since fabrication of high-quality graphene sheets requires the understanding of growth mechanisms, and methods of characterization and control of grain size of graphene flakes, analytical modeling of graphene growth process is therefore essential for controlled fabrication. The graphene growth process starts with randomly nucleated islands that gradually develop into complex shapes, grow in size, and eventually connect together to cover the copper foil. To model this complex process, we develop a physical-statistical approach under the assumption of self-similarity during graphene growth. The growth kinetics is uncovered by separating island shapes from area growth rate. We propose to characterize the area growth velocity using a confined exponential model, which not only has clear physical explanation, but also fits the real data well. For the shape modeling, we develop a parametric shape model which can be well explained by the angular-dependent growth rate. This work can provide useful information for the control and optimization of graphene growth process on Cu foil.

Time resolved PIV and flow visualization of 3D sheet cavitation

NASA Astrophysics Data System (ADS)

Foeth, E. J.; van Doorne, C. W. H.; van Terwisga, T.; Wieneke, B.

2006-04-01

Time-resolved PIV was applied to study fully developed sheet cavitation on a hydrofoil with a spanwise varying angle of attack. The hydrofoil was designed to have a three-dimensional cavitation pattern closely related to propeller cavitation, studied for its adverse effects as vibration, noise, and erosion production. For the PIV measurements, fluorescent tracer particles were applied in combination with an optical filter, in order to remove the reflections of the laser lightsheet by the cavitation. An adaptive mask was developed to find the interface between the vapor and liquid phase. The velocity at the interface of the cavity was found to be very close to the velocity predicted by a simple streamline model. For a visualization of the global flow dynamics, the laser beam was expanded and used to illuminate the entire hydrofoil and cavitation structure. The time-resolved recordings reveal the growth of the attached cavity and the cloud shedding. Our investigation proves the viability of accurate PIV measurements around developed sheet cavitation. The presented results will further be made available as a benchmark for the validation of numerical simulations of this complicated flow.

Canine corneal epithelial cells possess a sustained proliferative capacity and generate a spontaneously derived cell line.

PubMed

Morita, Maresuke; Fujita, Naoki; Abe, Momoko; Hayashimoto, Koji; Nakagawa, Takayuki; Nishimura, Ryohei; Tsuzuki, Keiko

2018-06-01

We have previously reported characteristics of canine corneal epithelial cells in vitro and found that canine corneal epithelial cells could maintain their proliferative capacity even after continuous culture without the use of feeder cells and growth promoting additives. The objective of this study was to elucidate proliferative characteristics of canine corneal epithelial cells independent of feeder cells and growth promoting additives, with the aim of developing a spontaneously derived corneal epithelial cell line. Canine and rabbit corneal epithelial cells were harvested from the limbus and cultured with, or without, feeder cells and growth promoting additives, and both were passaged continuously until growth arrest. Canine corneal epithelial cells could proliferate independently, and could be passaged more times than rabbit cells. A canine corneal epithelial cell line, cCEpi, which could be passaged more than 100 times without using feeder cells and growth promoting additives, was established. cCEpi cells maintained a cell morphology close to the primary culture and expressed p63, cytokeratin 15 (K15), and K3. Although changes in colony morphology, shortening of the population doubling time and a heteroploid karyotype were observed, cCEpi was not tumorigenic. Stratified cell sheets cultured from cCEpi were morphologically and immunohistologically similar to sheets cultivated from early passage cells. In conclusion, canine corneal epithelial cells can proliferate independent of feeder cells and growth promoting additives. cCEpi maintains properties similar to normal corneal epithelial cells and could be a useful source for studies in cellular biology and for developing novel therapies. Copyright © 2018 Elsevier Ltd. All rights reserved.

Extreme energetic particle decreases near geostationary orbit - A manifestation of current diversion within the inner plasma sheet

NASA Technical Reports Server (NTRS)

Baker, D. N.; Mcpherron, R. L.

1990-01-01

A qualitative model of magnetic field reconfiguration as might result from neutral line formation in the central plasma sheet late in a substorm growth phase is considered. It is suggested that magnetic reconnection probably begins before the substorm expansion phase and that cross-tail current is enhanced across the plasma sheet both earthward and tailward of a limited region near the neutral line. Such an enhanced cross-tail current earthward of the original X line region may contribute to thinning the plasma sheet substantially, and this would in turn affect the drift currents in that location, thus enhancing the current even closer toward the earth. In this way a redistribution and progressive diversion of normal cross-tail current throughout much of the inner portion of the plasma sheet could occur. The resulting intensified current, localized at the inner edge of the plasma sheet, would lead to a very thin plasma confinement region. This would explain the very taillike field and extreme particle dropouts often seen late in substorm growth phases.

Explosive Magnetic Reconnection in Double-current Sheet Systems: Ideal versus Resistive Tearing Mode

NASA Astrophysics Data System (ADS)

Baty, Hubert

2017-03-01

Magnetic reconnection associated with the tearing instability occurring in double-current sheet systems is investigated within the framework of resistive magnetohydrodynamics (MHD) in a two-dimensional Cartesian geometry. A special emphasis on the existence of fast and explosive phases is taken. First, we extend the recent theory on the ideal tearing mode of a single-current sheet to a double-current layer configuration. A linear stability analysis shows that, in long and thin systems with (length to shear layer thickness) aspect ratios scaling as {S}L9/29 (S L being the Lundquist number based on the length scale L), tearing modes can develop on a fast Alfvénic timescale in the asymptotic limit {S}L\\to ∞ . The linear results are confirmed by means of compressible resistive MHD simulations at relatively high S L values (up to 3× {10}6) for different current sheet separations. Moreover, the nonlinear evolution of the ideal double tearing mode (IDTM) exhibits a richer dynamical behavior than its single-tearing counterpart, as a nonlinear explosive growth violently ends up with a disruption when the two current layers interact trough the merging of plasmoids. The final outcome of the system is a relaxation toward a new state, free of magnetic field reversal. The IDTM dynamics is also compared to the resistive double tearing mode dynamics, which develops in similar systems with smaller aspect ratios, ≳ 2π , and exhibits an explosive secondary reconnection, following an initial slow resistive growth phase. Finally, our results are used to discuss the flaring activity in astrophysical magnetically dominated plasmas, with a particular emphasis on pulsar systems.

An Antarctic stratigraphic record of step-wise ice-sheet growth through the Eocene-Oligocene transition

NASA Astrophysics Data System (ADS)

Passchier, S.; Ciarletta, D. J.; Miriagos, T.; Bijl, P.; Bohaty, S. M.

2016-12-01

The Antarctic cryosphere plays a critical role in the ocean-atmosphere system, but its early evolution is still poorly known. With a near-field record from Prydz Bay, Antarctica, we conclude that Antarctic continental ice-sheet growth commenced with the EOT-1 "precursor" glaciation, during a time of Subantarctic surface ocean cooling and a decline in atmospheric pCO2. Prydz Bay lies downstream of a major East Antarctic ice-sheet drainage system and the Gamburtsev Mountains, a likely nucleation point for the first ice sheets. Its sedimentary records uniquely constrain the timing of ice-sheet advance onto the continental shelf. We investigate a detrital record extracted from three Ocean Drilling Program drill holes in Prydz Bay within a new depositional and chronological framework spanning the late Eocene to early Oligocene ( 36-33 Ma). The chemical index of alteration (CIA) and the S-index, calculated from the major element geochemistry of bulk samples, yield estimates of chemical weathering intensities and mean annual temperature (MAT) on the East Antarctic continent. We document evidence for late Eocene mountain glaciation along with transient warm events at 35.8-34.8 Ma. These data and our sedimentological analyses confirm the presence of ephemeral mountain glaciers on East Antarctica during the late Eocene between 35.9 and 34.4 Ma. Furthermore, we document the stepwise climate cooling of the Antarctic hinterland from 34.4 Ma as the ice sheet advanced towards the edges of the continent during EOT-1. The youngest part of our data set correlates to the time interval of the Oi-1 glaciation, when the ice-sheet in Prydz Bay extended to the outer shelf. Cooling and ice growth on Antarctica was spatially variable and ice sheets formed under declining pCO2. These results point to complex ice sheet - atmosphere - ocean - solid-earth feedbacks.

NASA Ares 1 Crew Launch Vehicle Upper Stage Configuration Selection Process

NASA Technical Reports Server (NTRS)

Cook, Jerry R.

2006-01-01

The Upper Stage Element of NASA s Ares I Crew Launch Vehicle (CLV) is a "clean-sheet" approach that is being designed and developed in-house, with Element management at MSFC. The USE concept is a self-supporting cylindrical structure, approximately 115 long and 216" in diameter. While the Reusable Solid Rocket Booster (RSRB) design has changed since the CLV inception, the Upper Stage Element design has remained essentially a clean-sheet approach. Although a clean-sheet upper stage design inherently carries more risk than a modified design, it does offer many advantages: a design for increased reliability; built-in extensibility to allow for commonality/growth without major redesign; and incorporation of state-of-the-art materials, hardware, and design, fabrication, and test techniques and processes to facilitate a potentially better, more reliable system.

Congenital cheek teratoma with temporo-mandibular joint ankylosis managed with ultra-thin silicone sheet interpositional arthroplasty.

PubMed

Bhatnagar, Ankur; Verma, Vinay Kumar; Purohit, Vishal

2013-01-01

Primary cheek teratomas are rare with < 5 reported cases. None had associated temporo mandibular joint ankylosis (TMJA). The fundamental aim in the treatment of TMJA is the successful surgical resection of ankylotic bone, prevention of recurrence, and aesthetic improvement by ensuring functional occlusion. Early treatment is necessary to promote proper growth and function of mandible and to facilitate the positive psychological development of child. Inter-positional arthroplasty with ultra-thin silicone sheet was performed. Advantages include short operative time, less foreign material in the joint space leading to negligible foreign body reactions and least chances of implant extrusion. Instead of excising a large bony segment, a thin silicone sheet was interposed and then sutured ensuring preservation of mandibular height. Aggressive post-operative physiotherapy with custom made dynamic jaw exerciser was used to prevent recurrence.

Area Reports. Advanced materials and devices research area. Silicon materials research task, and advanced silicon sheet task

NASA Technical Reports Server (NTRS)

1986-01-01

The objectives of the Silicon Materials Task and the Advanced Silicon Sheet Task are to identify the critical technical barriers to low-cost silicon purification and sheet growth that must be overcome to produce a PV cell substrate material at a price consistent with Flat-plate Solar Array (FSA) Project objectives and to overcome these barriers by performing and supporting appropriate R&D. Progress reports are given on silicon refinement using silane, a chemical vapor transport process for purifying metallurgical grade silicon, silicon particle growth research, and modeling of silane pyrolysis in fluidized-bed reactors.

Determination of Flaw Growth Characteristics of Ti-6Al-4V Sheet in the Solution-Treated and Aged Condition

NASA Technical Reports Server (NTRS)

Hoeppner, David W.; Pettit, Donald E.; Feddersen, Charles E.; Hyler, Walter S.

1968-01-01

The specific experimental investigation undertaken was designed to answer these questions on Ti-6Al-4V in the solution treated and aged condition. The defect growth and fracture characteristics were studied in parent (unwelded) and welded sheet material. The results of the study indicate that cryogenic proof testing will screen smaller size defects than proof testing at ambient conditions. However some unusual crack growth behavior during the proof test simulation suggests that some further study be made of stress and time duration effects.

Large area silicon sheet by EFG

NASA Technical Reports Server (NTRS)

Kalejs, J. P.

1982-01-01

Work carried out on the JPL Flat Plate Solar Array Project, for the purpose of developing a method for silicon ribbon production by Edge-defined Film-fed Growth (EEG) for use as low-cost substrate material in terrestrial solar cell manufacture, is described. A multiple ribbon furnace unit that is designed to operate on a continuous basis for periods of at least one week, with melt replenishment and automatic ribbon width control, and to produce silicon sheet at a rate of one square meter per hour, was constructed. Program milestones set for single ribbon furnace operation to demonstrate basic EEG system capabilities with respect to growth speed, thickness and cell performance were achieved for 10 cm wide ribbon: steady-state growth at 4 cm/min and 200 micron thickness over periods of an hour and longer was made routine, and a small area cell efficiency of 13+% demonstrated. Large area cells of average efficiency of 10 to 11%, with peak values of 11 to 12% were also achieved. The integration of these individual performance levels into multiple ribbon furnace operation was not accomplished.

CURRENT SHEET THINNING AND ENTROPY CONSTRAINTS DURING THE SUBSTORM GROWTH PHASE

NASA Astrophysics Data System (ADS)

Otto, A.; Hall, F., IV

2009-12-01

A typical property during the growth phase of geomagnetic substorms is the thinning of the near-Earth current sheet, most pronounced in the region between 6 and 15 R_E. We propose that the cause for the current sheet thinning is convection from the midnight tail region to the dayside to replenish magnetospheric magnetic flux which is eroded at the dayside as a result of dayside reconnection. Adiabatic convection from the near-Earth tail region toward the dayside must conserve the entropy on magnetic field lines. This constraint prohibits a source of the magnetic flux from a region further out in the magnetotail. Thus the near-Earth tail region is increasingly depleted of magnetic flux (the Erickson and Wolf [1980] problem) with entropy matching that of flux tubes that are eroded on the dayside. It is proposed that the magnetic flux depletion in the near-Earth tail forces the formation of thin current layers. The process is documented by three-dimensional MHD simulations. It is shown that the simulations yield a time scale, location, and other general characteristics of the current sheet evolution during the substorm growth phase.

Conservation in a World of Six Billion: A Grassroots Action Guide.

ERIC Educational Resources Information Center

Hren, Benedict J.

This grassroots action guide features a conservation initiative working to bring the impacts of human population growth, economic development, and natural resource consumption into balance with the limits of nature for the benefit of current and future generations. Contents include information sheets entitled "Six Billion People and Growing,""The…

Gainesville's urban forest canopy cover

Treesearch

Francisco Escobedo; Jennifer A. Seitz; Wayne Zipperer

2009-01-01

Ecosystem benefits from trees are linked directly to the amount of healthy urban forest canopy cover. Urban forest cover is dynamic and changes over time due to factors such as urban development, windstorms, tree removals, and growth. The amount of a city's canopy cover depends on its land use, climate, and people's preferences. This fact sheet examines how...

A 19-year radar altimeter elevation change time-series of the East and West Antarctic ice sheets

NASA Astrophysics Data System (ADS)

Sundal, A. V.; Shepherd, A.; Wingham, D.; Muir, A.; Mcmillan, M.; Galin, N.

2012-12-01

We present 19 years of continuous radar altimeter observations of the East and West Antarctic ice sheets acquired by the ERS-1, ERS-2, and ENVISAT satellites between May 1992 and September 2010. Time-series of surface elevation change were developed at 39,375 crossing points of the satellite orbit ground tracks using the method of dual cycle crossovers (Zwally et al., 1989; Wingham et al., 1998). In total, 46.5 million individual measurements were included in the analysis, encompassing 74 and 76 % of the East and West Antarctic ice sheet, respectively. The satellites were cross-calibrated by calculating differences between elevation changes occurring during periods of mission overlap. We use the merged time-series to explore spatial and temporal patterns of elevation change and to characterise and quantify the signals of Antarctic ice sheet imbalance. References: Wingham, D., Ridout, A., Scharroo, R., Arthern, R. & Shum, C.K. (1998): Antarctic elevation change from 1992 to 1996. Science, 282, 456-458. Zwally, H. J., Brenner, A. C., Major, J. A., Bindschadler, R. A. & Marsh, J. G. (1989): Growth of Greenland ice-sheet - measurements. Science, 246, 1587-1589.

Modeling the evolution of the Laurentide Ice Sheet from MIS 3 to the Last Glacial Maximum: an approach using sea level modeling and ice flow dynamics

NASA Astrophysics Data System (ADS)

Weisenberg, J.; Pico, T.; Birch, L.; Mitrovica, J. X.

2017-12-01

The history of the Laurentide Ice Sheet since the Last Glacial Maximum ( 26 ka; LGM) is constrained by geological evidence of ice margin retreat in addition to relative sea-level (RSL) records in both the near and far field. Nonetheless, few observations exist constraining the ice sheet's extent across the glacial build-up phase preceding the LGM. Recent work correcting RSL records along the U.S. mid-Atlantic dated to mid-MIS 3 (50-35 ka) for glacial-isostatic adjustment (GIA) infer that the Laurentide Ice Sheet grew by more than three-fold in the 15 ky leading into the LGM. Here we test the plausibility of a late and extremely rapid glaciation by driving a high-resolution ice sheet model, based on a nonlinear diffusion equation for the ice thickness. We initialize this model at 44 ka with the mid-MIS 3 ice sheet configuration proposed by Pico et al. (2017), GIA-corrected basal topography, and mass balance representative of mid-MIS 3 conditions. These simulations predict rapid growth of the eastern Laurentide Ice Sheet, with rates consistent with achieving LGM ice volumes within 15 ky. We use these simulations to refine the initial ice configuration and present an improved and higher resolution model for North American ice cover during mid-MIS 3. In addition we show that assumptions of ice loads during the glacial phase, and the associated reconstructions of GIA-corrected basal topography, produce a bias that can underpredict ice growth rates in the late stages of the glaciation, which has important consequences for our understanding of the speed limit for ice growth on glacial timescales.

An evaluation of the choice of feeder cell growth arrest for the production of cultured epidermis.

PubMed

Chugh, Rishi Man; Chaturvedi, Madhusudan; Yerneni, Lakshmana Kumar

2015-12-01

Growth arrested 3T3 cells have been used as feeder cells in human epidermal keratinocyte cultures to produce cultured epidermal autografts for the treatment of burns. The feeder cells were ideally growth-arrested by gamma-irradiation. Alternatively, growth arrest by mitomycin C treatment is a cost effective option. We compared the functional efficacy of these two approaches in keratinocyte cultures by colony forming efficiency, the net growth area of colonies, BrdU labeling and histological features of cultured epidermal sheets. The growth area estimation involved a semi-automated digital technique using the Adobe Photoshop and comprised of isolation and enumeration of red pixels in Rhodamine B-stained keratinocyte colonies. A further refinement of the technique led to the identification of critical steps to increasing the degree of accuracy and enabling its application as an extension of colony formation assay. The results on feeder cell functionality revealed that the gamma irradiated feeders influenced significantly higher colony forming efficiency and larger growth area than the mitomycin C treated feeders. The BrdU labeling study indicated significant stimulation of the overall keratinocyte proliferation by the gamma irradiated feeders. The cultured epidermal sheets produced by gamma feeders were relatively thicker than those produced by mitomycin C feeders. We discussed the clinical utility of mitomycin C feeders from the viewpoint of cost-effective burn care in developing countries. Copyright © 2015 Elsevier Ltd and ISBI. All rights reserved.

Full-Thickness Skin Wound Healing Using Human Placenta-Derived Extracellular Matrix Containing Bioactive Molecules

PubMed Central

Choi, Ji Suk; Kim, Jae Dong; Yoon, Hyun Soo

2013-01-01

The human placenta, a complex organ, which facilitates exchange between the fetus and the mother, contains abundant extracellular matrix (ECM) components and well-preserved endogenous growth factors. In this study, we designed a new dermal substitute from human placentas for full-thickness wound healing. Highly porous, decellularized ECM sheets were fabricated from human placentas via homogenization, centrifugation, chemical and enzymatic treatments, molding, and freeze-drying. The physical structure and biological composition of human placenta-derived ECM sheets dramatically supported the regeneration of full-thickness wound in vivo. At the early stage, the ECM sheet efficiently absorbed wound exudates and tightly attached to the wound surface. Four weeks after implantation, the wound was completely closed, epidermic cells were well arranged and the bilayer structure of the epidermis and dermis was restored. Moreover, hair follicles and microvessels were newly formed in the ECM sheet-implanted wounds. Overall, the ECM sheet produced a dermal substitute with similar cellular organization to that of normal skin. These results suggest that human placenta-derived ECM sheets provide a microenvironment favorable to the growth and differentiation of cells, and positive modulate the healing of full-thickness wounds. PMID:22891853

Generation of Alfvenic Waves and Turbulence in Magnetic Reconnection Jets

NASA Astrophysics Data System (ADS)

Hoshino, M.

2014-12-01

The magneto-hydro-dynamic (MHD) linear stability for the plasma sheet with a localized bulk plasma flow parallel to the neutral sheet is investigated. We find three different unstable modes propagating parallel to the anti-parallel magnetic field line, and we call them as "streaming　tearing'', "streaming sausage'', and "streaming kink'' mode. The streaming tearing and sausage modes have the tearing mode-like structure with symmetric density fluctuation to the neutral sheet, and the streaming kink mode has the asymmetric fluctuation.　The growth rate of the streaming tearing mode decreases with increasing the magnetic Reynolds number, while those of the streaming　sausage and kink modes do not strongly depend on the Reynolds number. The wavelengths of these unstable modes are of the order of the thickness of plasma sheet, which behavior is almost same as the standard　tearing mode with no bulk flow. Roughly speaking the growth rates of　three modes become faster than the standard tearing mode. The situation of the plasma sheet with the bulk flow can be realized in the reconnection exhaust with the Alfvenic reconnection jet, and the unstable modes may be regarded as one of the generation processes of Alfvenic　turbulence in the plasma sheet during magnetic reconnection.

Congenital cheek teratoma with temporo-mandibular joint ankylosis managed with ultra-thin silicone sheet interpositional arthroplasty

PubMed Central

Bhatnagar, Ankur; Verma, Vinay Kumar; Purohit, Vishal

2013-01-01

Primary cheek teratomas are rare with < 5 reported cases. None had associated temporo mandibular joint ankylosis (TMJA). The fundamental aim in the treatment of TMJA is the successful surgical resection of ankylotic bone, prevention of recurrence, and aesthetic improvement by ensuring functional occlusion. Early treatment is necessary to promote proper growth and function of mandible and to facilitate the positive psychological development of child. Inter-positional arthroplasty with ultra-thin silicone sheet was performed. Advantages include short operative time, less foreign material in the joint space leading to negligible foreign body reactions and least chances of implant extrusion. Instead of excising a large bony segment, a thin silicone sheet was interposed and then sutured ensuring preservation of mandibular height. Aggressive post-operative physiotherapy with custom made dynamic jaw exerciser was used to prevent recurrence. PMID:24163567

Modelling large-scale ice-sheet-climate interactions at the last glacial inception

NASA Astrophysics Data System (ADS)

Browne, O. J. H.; Gregory, J. M.; Payne, A. J.; Ridley, J. K.; Rutt, I. C.

2010-05-01

In order to investigate the interactions between coevolving climate and ice-sheets on multimillenial timescales, a low-resolution atmosphere-ocean general circulation model (AOGCM) has been coupled to a three-dimensional thermomechanical ice-sheet model. We use the FAMOUS AOGCM, which is almost identical in formulation to the widely used HadCM3 AOGCM, but on account of its lower resolution (7.5° longitude × 5° latitude in the atmosphere, 3.75°× 2.5° in the ocean) it runs about ten times faster. We use the community ice-sheet model Glimmer at 20 km resolution, with the shallow ice approximation and an annual degree-day scheme for surface mass balance. With the FAMOUS-Glimmer coupled model, we have simulated the growth of the Laurentide and Fennoscandian ice sheets at the last glacial inception, under constant orbital forcing and atmospheric composition for 116 ka BP. Ice grows in both regions, totalling 5.8 m of sea-level equivalent in 10 ka, slower than proxy records suggest. Positive climate feedbacks reinforce this growth at local scales (order hundreds of kilometres), where changes are an order of magnitude larger than on the global average. The albedo feedback (higher local albedo means a cooler climate) is important in the initial expansion of the ice-sheet area. The topography feedback (higher surface means a cooler climate) affects ice-sheet thickness and is not noticeable for the first 1 ka. These two feedbacks reinforce each other. Without them, the ice volume is ~90% less after 10 ka. In Laurentia, ice expands initially on the Canadian Arctic islands. The glaciation of the islands eventually cools the nearby mainland climate sufficiently to produce a positive mass balance there. Adjacent to the ice-sheets, cloud feedbacks tend to reduce the surface mass balance and restrain ice growth; this is an example of a local feedback whose simulation requires a model that includes detailed atmospheric physics.

Improved damage tolerance of titanium by adhesive lamination

NASA Technical Reports Server (NTRS)

Johnson, W. S.

1982-01-01

Basic damage tolerance properties of Ti-6A1-4V titanium plate can be improved by laminating thin sheets of titanium with adhesives. Compact tension and center cracked tension specimens made from thick plate, thin sheet, and laminated plate (six plies of thin sheet) were tested. The fracture toughness of the laminated plate was 39 percent higher than the monolithic plate. The laminated plate's through the thickness crack growth rate was about 20 percent less than that of the monolithic plate. The damage tolerance life of the surface cracked laminate was 6 to over 15 times the life of a monolithic specimen. A simple method of predicting crack growth in a crack ply of a laminate is presented.

Glacial geomorphic evidence for a late climatic change on Mars

NASA Technical Reports Server (NTRS)

Kargel, J. S.; Strom, R. G.

1992-01-01

In a series of preliminary reports, we documented evidence of former glacial epochs on Mars. Apparent glacial landforms seemed to be concentrated primarily at middle to high southern latitudes. We now have additional evidence supporting the view that Martian glaciation appears to have been more extensive than previously recognized. The growth and collapse of ice sheets on Mars seems closely analogous to the growth and decline of Earth's great Pleistocene ice sheets. This implies that climate change was probably somewhat comparable on the two planets, although in the case of Mars the entire planet seems to have changed rapidly to a cold, dry present-day environment after the collapse of the ice sheets.

Ternary Aligned Nanofibers of RGD Peptide-Displaying M13 Bacteriophage/PLGA/Graphene Oxide for Facilitated Myogenesis

PubMed Central

Shin, Yong Cheol; Kim, Chuntae; Song, Su-Jin; Jun, Seungwon; Kim, Chang-Seok; Hong, Suck Won; Hyon, Suong-Hyu; Han, Dong-Wook; Oh, Jin-Woo

2018-01-01

Recently, there have been tremendous efforts to develop the biofunctional scaffolds by incorporating various biochemical factors. In the present study, we fabricated poly(lactic-co-glycolic acid) (PLGA) nanofiber sheets decorated with graphene oxide (GO) and RGD peptide. The decoration of GO and RGD peptide was readily achieved by using RGD peptide-displaying M13 bacteriophage (RGD-M13 phage) and electrospinning. Furthermore, the aligned GO-decorated PLGA/RGD peptide (GO-PLGA/RGD) ternary nanofiber sheets were prepared by magnetic field-assisted electrospinning, and their potentials as bifunctional scaffolds for facilitating myogenesis were explored. We characterized the physicochemical and mechanical properties of the sheets by scanning electron microscopy, Raman spectroscopy, contact angle measurement, and tensile test. In addition, the C2C12 skeletal myoblasts were cultured on the aligned GO-PLGA/RGD nanofiber sheets, and their cellular behaviors, including initial attachment, proliferation and myogenic differentiation, were evaluated. Our results revealed that the GO-PLGA/RGD nanofiber sheets had suitable physicochemical and mechanical properties for supporting cell growth, and could significantly promote the spontaneous myogenic differentiation of C2C12 skeletal myoblasts. Moreover, it was revealed that the myogenic differentiation was further accelerated on the aligned GO-PLGA/RGD nanofiber sheets due to the synergistic effects of RGD peptide, GO and aligned nanofiber structure. Therefore, , it is suggested that the aligned GO-PLGA/RGD ternary nanofiber sheets are one of the most promising approaches for facilitating myogenesis and promoting skeletal tissue regeneration. PMID:29577018

Ternary Aligned Nanofibers of RGD Peptide-Displaying M13 Bacteriophage/PLGA/Graphene Oxide for Facilitated Myogenesis.

PubMed

Shin, Yong Cheol; Kim, Chuntae; Song, Su-Jin; Jun, Seungwon; Kim, Chang-Seok; Hong, Suck Won; Hyon, Suong-Hyu; Han, Dong-Wook; Oh, Jin-Woo

2018-01-01

Recently, there have been tremendous efforts to develop the biofunctional scaffolds by incorporating various biochemical factors. In the present study, we fabricated poly(lactic- co -glycolic acid) (PLGA) nanofiber sheets decorated with graphene oxide (GO) and RGD peptide. The decoration of GO and RGD peptide was readily achieved by using RGD peptide-displaying M13 bacteriophage (RGD-M13 phage) and electrospinning. Furthermore, the aligned GO-decorated PLGA/RGD peptide (GO-PLGA/RGD) ternary nanofiber sheets were prepared by magnetic field-assisted electrospinning, and their potentials as bifunctional scaffolds for facilitating myogenesis were explored. We characterized the physicochemical and mechanical properties of the sheets by scanning electron microscopy, Raman spectroscopy, contact angle measurement, and tensile test. In addition, the C2C12 skeletal myoblasts were cultured on the aligned GO-PLGA/RGD nanofiber sheets, and their cellular behaviors, including initial attachment, proliferation and myogenic differentiation, were evaluated. Our results revealed that the GO-PLGA/RGD nanofiber sheets had suitable physicochemical and mechanical properties for supporting cell growth, and could significantly promote the spontaneous myogenic differentiation of C2C12 skeletal myoblasts. Moreover, it was revealed that the myogenic differentiation was further accelerated on the aligned GO-PLGA/RGD nanofiber sheets due to the synergistic effects of RGD peptide, GO and aligned nanofiber structure. Therefore, , it is suggested that the aligned GO-PLGA/RGD ternary nanofiber sheets are one of the most promising approaches for facilitating myogenesis and promoting skeletal tissue regeneration.

Nanoscale Strontium Titanate Sheets and Crystals

NASA Astrophysics Data System (ADS)

Tilka, Jack Andrew

The physical properties of materials are dominated by their structure and composition. Insight into the structure of complex oxide materials has the potential to improve our understanding and eventually control of their physical properties. This PhD thesis reports the development of characterization and fabrication techniques relevant to improving the scientific understanding of complex oxide materials. The work presented here has two components. I report a way to use ideas that were originally developed in semiconductor processing to control the elastic strain state and crystallization process of the model complex oxide SrTiO3. An additional component is an important series of advances in the analysis of diffraction patterns acquired with focused x-ray nanobeams. The fabrication and characterization of nanoscale SrTiO3 has been experimentally shown to allow the introduction of elastic strain into SrTiO3. The creation of thin SrTiO3 crystals from (001)-oriented SrTiO3 bulk single crystals using focused ion beam milling techniques yields sheets with submicron thickness and arbitrary orientation within the (001) plane. Synchrotron x-ray nanodiffraction experiments show that the SrTiO 3 sheets have rocking curves with angular widths less than 0.02°. These widths are less than a factor of two larger than bulk SrTiO3, which shows that the sheets are suitable substrates for epitaxial thin film growth. A precisely selected elastic strain can be introduced into the SrTiO 3 sheets using a silicon nitride stressor layer. Synchrotron x-ray nanodiffraction studies show that the strain introduced in the SrTiO3 sheets is on the order of 10-4, matching the predictions of an elastic model. This approach to elastic strain sharing in complex oxides allows the strain to be selected within a wide and continuous range of values, an effect not achievable in heteroepitaxy on rigid substrates. An additional fabrication technique is also evaluated here based on the crystallization of SrTiO3 from initially amorphous thin films. This process is known as solid-phase epitaxy in two-dimensional samples but is just beginning to be explored in more complex geometries. I report experiments in both homoepitaxy and heteroepitaxy including measurements of crystal growth rates and the crystallographic orientations of crystals formed in this way. The lateral growth rates are consistent with previously measured vertical growth. This result indicated that previous work on vertical solid-phase epitaxy could be extended into lateral solid-phase epitaxy, which has the power to be applied to complicated non-planar geometries. The highly coherent and tightly focused x-ray beams produced by hard x-ray light sources enable the nanoscale structural characterization of materials but are accompanied by significant challenges in the interpretation of diffraction and scattering patterns. I report here a series of methods that expand the range of physical problems that can be accurately captured by coherent x-ray optical simulations. My approach has been to expand simulations methods to include arbitrary x-ray incident angles and arbitrary epitaxial heterostructures. I first applied these methods to extract the misorientation of lattice planes and the strain of individual layers of Si/SiGe heterostructures relevant to applications in quantum electronics. Further applications reported in this thesis are in probing defects created in the processing of SrTiO3 and in measuring the change in lattice parameter introduced into strained SrTiO3 sheets. The systematic interpretation of nanobeam diffraction patterns aids in the fabrication of SrTiO3 nanostructures.

Modeling the growth and decay of the Antarctic Peninsula Ice Sheet

NASA Astrophysics Data System (ADS)

Payne, A. J.; Sugden, D. E.; Clapperton, C. M.

1989-03-01

A model of the growth and decay of the Antarctic Peninsula Ice Sheet during the last glacial/interglacial cycle is used to identify the main controls on ice sheet behavior. Using as input glaciological assumptions derived by W. F. Budd and I. N. Smith (1982, Annals of Glaciology3, 42-49), bedrock topography, isostatic compensation, and mass balance relationships, the model is driven by sea-level change over the last 40,000 yr in association with assumed changes in the rate of melting beneath ice shelves. An ice sheet dome over 3.5 km thick grows on the offshore shelf and straits west of the Antarctic Peninsula and reaches a maximum at 18,000 yr B.P. Collapse begins at 14,000 yr B.P. but becomes rapid and continuous after 10,000 yr B.P. The present stable ice cover is achieved at 6500 yr B.P. Ice growth and decay are characterized by thresholds which separate periods of steady state from periods of rapid transition; the thresholds usually relate to topography. Tests show that ice sheet behavior is most sensitive to sea-level change, basal marine melting, and accumulation and is less sensitive to isostasy, spatial variation in accumulation, calving rates, and ice flow parameterization. Tests of the model against field evidence show good agreement in places, as well as discrepancies which require further work.

Growth Factor-Reinforced ECM Fabricated from Chemically Hypoxic MSC Sheet with Improved In Vivo Wound Repair Activity.

PubMed

Du, Hui-Cong; Jiang, Lin; Geng, Wen-Xin; Li, Jing; Zhang, Rui; Dang, Jin-Ge; Shu, Mao-Guo; Li, Li-Wen

2017-01-01

MSC treatment can promote cutaneous wound repair through multiple mechanisms, and paracrine mediators secreted by MSC are responsible for most of its therapeutic benefits. Recently, MSC sheet composed of live MSCs and their secreted ECMs was reported to promote wound healing; however, whether its ECM alone could accelerate wound closure remained unknown. In this study, Nc-ECM and Cc-ECM were prepared from nonconditioned and CoCl 2 -conditioned MSC sheets, respectively, and their wound healing properties were evaluated in a mouse model of full-thickness skin defect. Our results showed that Nc-ECM can significantly promote wound repair through early adipocyte recruitment, rapid reepithelialization, enhanced granulation tissue growth, and augmented angiogenesis. Moreover, conditioning of MSC sheet with CoCl 2 dramatically enriched its ECM with collagen I, collagen III, TGF- β 1, VEGF, and bFGF via activation of HIF-1 α and hence remarkably improved its ECM's in vivo wound healing potency. All the Cc-ECM-treated wounds completely healed on day 7, while Nc-ECM-treated wounds healed about 85.0% ± 8.6%, and no-treatment wounds only healed 69.8% ± 9.6% ( p < 0.05). Therefore, we believe that such growth factor-reinforced ECM fabricated from chemically hypoxic MSC sheet has the potential for clinical translation and will lead to a MSC-derived, cost-effective, bankable biomaterial for wound management.

Cultures of Schwann-like cells differentiated from adipose-derived stem cells on PDMS/MWNT sheets as a scaffold for peripheral nerve regeneration.

PubMed

Han, In Ho; Sun, Fangfang; Choi, Yoon Ji; Zou, Fengming; Nam, Kyoung Hyup; Cho, Won Ho; Choi, Byung Kwan; Song, Geun Sung; Koh, Kwangnak; Lee, Jaebeom

2015-11-01

Carbon nanotubes (CNTs) are promising candidates as novel scaffolds for peripheral nerve regeneration. Schwann cells (SCs) are attractive therapeutic targets due to their pivotal role in peripheral nerve regeneration, but primary SCs have limitations for clinical application. However, adipose-derived stem cells (ASCs) may differentiate into Schwann-like cells. The present study assesses the potential applicability of multiwall CNTs (MWNTs) composited with polydimethylsiloxane (PDMS), which were then seeded with differentiated adipose-derived stem cells (dASCs) to promote neuronal differentiation and growth. Aqueous MWNT dispersion was filtered, and the PDMS/MWNT sheets were prepared using a simple printing-transfer method. Characterization of PDMS/MWNT sheets indicated their unique physical properties, such as superior mechanical strength and electroconductivity, compared with bare PDMS sheets. ASCs were differentiated into Schwann-like cells using a mixture of glial growth factors. Dorsal root ganglion (DRG) neurons were co-cultured with SCs and dASCs on PDMS/MWNTs sheets or noncoated dishes. An alamar blue proliferation assay of dASC and SCs showed significantly more dASC and SCs cultured on PDMS/MWNT sheets at 48 h and 72 h than when cultured on noncoated dishes (p < 0.05). Additionally, when DRG were cultured on PDMS/MWNT sheets seeded with dASCs, the proliferation of DRG neurons and the longest neurite outgrowth length per neuron were significantly greater than when DRG were cultured on PDMS/MWNT sheets alone or on noncoated dishes seeded with SCs or dASCs (p < 0.05). Overall, PDMS/MWNT sheets exhibited excellent biocompatibility for culturing Schwann-like cells differentiated from ASCs. Seeding the dASCs on PDMS/MWNT sheets may produce synergistic effects in peripheral nerve regeneration, similarly to SCs. © 2015 Wiley Periodicals, Inc.

Large Area Silicon Sheet by EFG

NASA Technical Reports Server (NTRS)

Wald, F. V.

1979-01-01

Progress made in the development of EFG ribbon growth is discussed. Specific areas covered include: (1) demonstration of multiple growth for ribbons 5 cm wide in runs of 12 and 20 hours duration; (2) a single cartridge crystal growth station was built expanding observational capacity by virtue of an anamorphic optical-video system which allows close observation of the meniscus over 7.5 cm wide, as well as video taping of the ribbon growth process; (3) growth station no.1 achieved reproducible and reliable growth of 7.5 cm wide ribbon at speeds up to 4 cm/min; (4) introduction of the 'mini cold shoe'; (5) increases in cell efficiency due to interface shaping using the 'displaced die' concept; and (6) clarification of the role of gaseous impurities in cartridge furnaces and stabilization of their destabilizing influence on growth.

Large area silicon sheet by EFG. [furnace growth techniques

NASA Technical Reports Server (NTRS)

1981-01-01

The development of a technique for the production of silicon ribbon is discussed. Extensive characterization of the multiple ribbon Furnace 3A main zone temperature profile was performed and the information used to improve uniformity of heating. Irregularities in the main zone heater were associated with growth difficulties at specific cartridge locations, and growth conditions subsequently improved by profiling the main zone heater. Good growth conditions were established in all three cartridge positions. These improvements allowed multiple growth of three 10 cm wide ribbons to be demonstrated for periods of an hour on several occasions. A gas distribution system for the 10 cm cartridge was introduced and demonstrated to lead to improved ambient control during growth. Growth without and with CO2 showed that quality improvement in 10 cm ribbon grown with cold shoes results from ambient manipulation.

Nonlinear evolution of three-dimensional instabilities of thin and thick electron scale current sheets: Plasmoid formation and current filamentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Neeraj; Büchner, Jörg; Max Planck Institute for Solar System Research, Justus-Von-Liebig-Weg-3, Göttingen

Nonlinear evolution of three dimensional electron shear flow instabilities of an electron current sheet (ECS) is studied using electron-magnetohydrodynamic simulations. The dependence of the evolution on current sheet thickness is examined. For thin current sheets (half thickness =d{sub e}=c/ω{sub pe}), tearing mode instability dominates. In its nonlinear evolution, it leads to the formation of oblique current channels. Magnetic field lines form 3-D magnetic spirals. Even in the absence of initial guide field, the out-of-reconnection-plane magnetic field generated by the tearing instability itself may play the role of guide field in the growth of secondary finite-guide-field instabilities. For thicker current sheetsmore » (half thickness ∼5 d{sub e}), both tearing and non-tearing modes grow. Due to the non-tearing mode, current sheet becomes corrugated in the beginning of the evolution. In this case, tearing mode lets the magnetic field reconnect in the corrugated ECS. Later thick ECS develops filamentary structures and turbulence in which reconnection occurs. This evolution of thick ECS provides an example of reconnection in self-generated turbulence. The power spectra for both the thin and thick current sheets are anisotropic with respect to the electron flow direction. The cascade towards shorter scales occurs preferentially in the direction perpendicular to the electron flow.« less

Linear growth rates of resistive tearing modes with sub-Alfvénic streaming flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, L. N.; College of Sciences, China Jiliang University, Hangzhou 310018; Ma, Z. W., E-mail: zwma@zju.edu.cn

2014-07-15

The tearing instability with sub-Alfvénic streaming flow along the external magnetic field is investigated using resistive MHD simulation. It is found that the growth rate of the tearing mode instability is larger than that without the streaming flow. With the streaming flow, there exist two Alfvén resonance layers near the central current sheet. The larger perturbation of the magnetic field in two closer Alfvén resonance layers could lead to formation of the observed cone structure and can largely enhance the development of the tearing mode for a narrower streaming flow. For a broader streaming flow, a larger separation of Alfvénmore » resonance layers reduces the magnetic reconnection. The linear growth rate decreases with increase of the streaming flow thickness. The growth rate of the tearing instability also depends on the plasma beta (β). When the streaming flow is embedded in the current sheet, the growth rate increases with β if β < β{sub s}, but decreases if β > β{sub s}. The existence of the specific value β{sub s} can be attributed to competition between the suppressing effect of β and the enhancing effect of the streaming flow on the magnetic reconnection. The critical value β{sub s} increases with increase of the streaming flow strength.« less

Current Sheet Thinning Associated with Dayside Reconnection

NASA Astrophysics Data System (ADS)

Hsieh, M.; Otto, A.; Ma, X.

2011-12-01

The thinning of the near-Earth current sheet during the growth phase is of critical importance to understand geomagnetic substorms and the conditions that lead to the onset of the expansion phase. We have proposed that convection from the midnight tail region to the dayside as the cause for this current sheet thinning. Adiabatic convection from the near-Earth tail region toward the dayside must conserve the entropy on magnetic field lines. This constraint prohibits a source of the magnetic flux from a region further out in the magnetotail. Thus the near-Earth tail region is increasingly depleted of magnetic flux (the Erickson and Wolf [1980] problem) with entropy matching that of flux tubes that are eroded on the dayside. The process is examined by three-dimensional MHD simulations. The properties of the current sheet thinning are determined as a function of the magnitude of convection toward the dayside and the lobe boundary conditions. It is shown that the model yields a time scale, location, and other general characteristics of the current sheet evolution consistent with observations during the substorm growth phase.

A mechanism for magnetospheric substorms

NASA Technical Reports Server (NTRS)

Erickson, G. M.; Heinemann, M.

1994-01-01

Energy-principle analysis performed on two-dimensional, self-consistent solutions for magnetospheric convection indicates that the magnetosphere is unstable to isobaric (yet still frozen-in) fluctuations of plasma-sheet flux tubes. Normally, pdV work associated with compression maintains stability of the inward/outward oscillating normal mode. However, if Earth's ionosphere can provide sufficient mass flux, isobaric expansion of flux tubes can occur. The growth of a field-aligned potential drop in the near-Earth, midnight portion of the plasma sheet, associated with upward field-aligned currents responsible for the Harang discontinuity, redistributes plasma along field lines in a manner that destabilizes the normal mode. The growth of this unstable mode results in an out-of-equilibrium situation near the inner edge. When this occurs over a downtail extent comparable to the half-thickness of the plasma sheet, collapse ensues and forces thinning of the plasma sheet whereby conditions favorable to reconnection occur. This scenario for substorm onset is consistent with observed upward fluxes of ions, parallel potential drops, and observations of substorm onset. These observations include near Earth onset, pseudobreakups, the substorm current wedge, and local variations of plasma-sheet thickness.

Dynamics of Radially Expanding Liquid Sheets

NASA Astrophysics Data System (ADS)

Majumdar, Nayanika; Tirumkudulu, Mahesh S.

2018-04-01

The process of atomization often involves ejecting thin liquid sheets at high speeds from a nozzle that causes the sheet to flap violently and break up into fine droplets. The flapping of the liquid sheet has long been attributed to the sheet's interaction with the surrounding gas phase. Here, we present experimental evidence to the contrary and show that the flapping is caused by the thinning of the liquid sheet as it spreads out from the nozzle exit. The measured growth rates of the waves agree remarkably well with the predictions of a recent theory that accounts for the sheet's thinning but ignores aerodynamic interactions. We anticipate these results to not only lead to more accurate predictions of the final drop-size distribution but also enable more efficient designs of atomizers.

Enhanced sensitivity in non-enzymatic glucose detection by improved growth kinetics of Ni-based nanostructures.

PubMed

Urso, M; Pellegrino, G; Strano, V; Bruno, E; Priolo, F; Mirabella, S

2018-04-20

Ni-based nanostructures are attractive catalytic materials for many electrochemical applications, among which are non-enzymatic sensing, charge storage, and water splitting. In this work, we clarify the synthesis kinetics of Ni(OH) 2 /NiOOH nanowalls grown by chemical bath deposition at room temperature and at 50 °C. We applied the results to non-enzymatic glucose sensing, reaching a highest sensitivity of 31 mA cm -2 mM -1 . Using scanning electron microscopy, x-ray diffraction analysis and Rutherford backscattering spectrometry we found that the growth occurs through two regimes: first, a quick random growth leading to disordered sheets of Ni oxy-hydroxide, followed by a slower growth of well-aligned sheets of Ni hydroxide. A high growth temperature (50 °C), leading mainly to well-aligned sheets, offers superior electrochemical properties in terms of charge storage, charge carrier transport and catalytic action, as confirmed by cyclic voltammetry and electrochemical impedance spectroscopy analyses. The reported results on the optimization and application of low-cost synthesis of these Ni-based nanostructures have a large potential for application in catalysis, (bio)sensing, and supercapacitors areas.

Enhanced sensitivity in non-enzymatic glucose detection by improved growth kinetics of Ni-based nanostructures

NASA Astrophysics Data System (ADS)

Urso, M.; Pellegrino, G.; Strano, V.; Bruno, E.; Priolo, F.; Mirabella, S.

2018-04-01

Ni-based nanostructures are attractive catalytic materials for many electrochemical applications, among which are non-enzymatic sensing, charge storage, and water splitting. In this work, we clarify the synthesis kinetics of Ni(OH)2/NiOOH nanowalls grown by chemical bath deposition at room temperature and at 50 °C. We applied the results to non-enzymatic glucose sensing, reaching a highest sensitivity of 31 mA cm-2mM-1. Using scanning electron microscopy, x-ray diffraction analysis and Rutherford backscattering spectrometry we found that the growth occurs through two regimes: first, a quick random growth leading to disordered sheets of Ni oxy-hydroxide, followed by a slower growth of well-aligned sheets of Ni hydroxide. A high growth temperature (50 °C), leading mainly to well-aligned sheets, offers superior electrochemical properties in terms of charge storage, charge carrier transport and catalytic action, as confirmed by cyclic voltammetry and electrochemical impedance spectroscopy analyses. The reported results on the optimization and application of low-cost synthesis of these Ni-based nanostructures have a large potential for application in catalysis, (bio)sensing, and supercapacitors areas.

Low Angle Silicon Sheet Growth. Large Area Silicon Sheet Task Low Cost Solar Array Project

NASA Technical Reports Server (NTRS)

1982-01-01

The results of a program to demonstrate the feasibility of a low angle silicon ribbon growth process are described. Twenty-six experimental runs were performed. Ribbons were grown at pull rates from 5 to 68 cm/min. Ribbon lengths up to 74 cm were grown while widths varied from 5 to 25 mm. Thicknesses varied from 0.6 to 2.5 mm, with typical values of about 1 mm.

Soft Costs Fact Sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2016-05-01

This fact sheet is an overview of the systems integration subprogram at the U.S. Department of Energy SunShot Initiative. Soft costs can vary significantly as a result of a fragmented energy marketplace. In the U.S., there are 18,000 jurisdictions and 3,000 utilities with different rules and regulations for how to go solar. The same solar equipment may vary widely in its final installation price due to process and market variations across jurisdictions, creating barriers to rapid industry growth. SunShot supports the development of innovative solutions that enable communities to build their local economies and establish clean energy initiatives that meetmore » their needs, while at the same time creating sustainable solar market conditions.« less

Climate Process Team "Representing calving and iceberg dynamics in global climate models"

NASA Astrophysics Data System (ADS)

Sergienko, O. V.; Adcroft, A.; Amundson, J. M.; Bassis, J. N.; Hallberg, R.; Pollard, D.; Stearns, L. A.; Stern, A. A.

2016-12-01

Iceberg calving accounts for approximately 50% of the ice mass loss from the Greenland and Antarctic ice sheets. By changing a glacier's geometry, calving can also significantly perturb the glacier's stress-regime far upstream of the grounding line. This process can enhance discharge of ice across the grounding line. Once calved, icebergs drift into the open ocean where they melt, injecting freshwater to the ocean and affecting the large-scale ocean circulation. The spatial redistribution of the freshwater flux have strong impact on sea-ice formation and its spatial variability. A Climate Process Team "Representing calving and iceberg dynamics in global climate models" was established in the fall 2014. The major objectives of the CPT are: (1) develop parameterizations of calving processes that are suitable for continental-scale ice-sheet models that simulate the evolution of the Antarctic and Greenland ice sheets; (2) compile the data sets of the glaciological and oceanographic observations that are necessary to test, validate and constrain the developed parameterizations and models; (3) develop a physically based iceberg component for inclusion in the large-scale ocean circulation model. Several calving parameterizations based suitable for various glaciological settings have been developed and implemented in a continental-scale ice sheet model. Simulations of the present-day Antarctic and Greenland ice sheets show that the ice-sheet geometric configurations (thickness and extent) are sensitive to the calving process. In order to guide the development as well as to test calving parameterizations, available observations (of various kinds) have been compiled and organized into a database. Monthly estimates of iceberg distribution around the coast of Greenland have been produced with a goal of constructing iceberg size distribution and probability functions for iceberg occurrence in particular regions. A physically based iceberg model component was used in a GFDL global climate model. The simulation results show that the Antarctic iceberg calving-size distribution affects iceberg trajectories, determines where iceberg meltwater enters the ocean and the increased ice-berg freshwater transport leads to increased sea-ice growth around much of the East Antarctic coastline.

Growth and Development of Three-Dimensional Plant Form.

PubMed

Whitewoods, Christopher D; Coen, Enrico

2017-09-11

Plants can generate a spectacular array of complex shapes, many of which exhibit elaborate curvature in three dimensions, illustrated for example by orchid flowers and pitcher-plant traps. All of these structures arise through differential growth. Recent findings provide fresh mechanistic insights into how regional cell behaviours may lead to tissue deformations, including anisotropies and curvatures, which shape growing volumes and sheets of cells. Here were review our current understanding of how genes, growth, mechanics, and evolution interact to generate diverse structures. We illustrate problems and approaches with the complex three-dimensional trap of the bladderwort, Utricularia gibba, to show how a multidisciplinary approach can be extended to new model systems to understand how diverse plant shapes can develop and evolve. Copyright © 2017 Elsevier Ltd. All rights reserved.

Multipotent mesenchymal stromal cell sheet therapy for bisphosphonate-related osteonecrosis of the jaw in a rat model.

PubMed

Kaibuchi, Nobuyuki; Iwata, Takanori; Yamato, Masayuki; Okano, Teruo; Ando, Tomohiro

2016-09-15

Bisphosphonates (BPs) inhibit bone resorption and are frequently used to treat osteoporosis, bone metastasis, and other conditions that result in bone fragility. However, numerous studies have reported that BPs are closely related to the development of osteonecrosis of the jaw (BRONJ), which is an intractable disease. Recent studies have demonstrated that intravenous infusion of multipotent mesenchymal stromal cells (MSCs) is effective for the treatment of BRONJ-like disease models. However, the stability of injected MSCs is relatively low. In this study, the protein level of vascular endothelial growth factor in BP-treated MSCs was significantly lower than untreated-MSCs. The mRNA expression levels of receptor activator of nuclear factor κ-B ligand and osteoprotegerin were significantly decreased in BP-treated MSCs. We developed a tissue-engineered cell sheet of allogeneic enhanced green fluorescent protein (EGFP)-labeled MSCs and investigated the effect of MSC sheet transplantation in a BRONJ-like rat model. The MSC sheet group showed wound healing in most cases compared with the control group and MSC intravenous injection group (occurrence of bone exposure: 12.5% compared with 80% and 100%, respectively). Immunofluorescence staining revealed that EGFP-positive cells were localized around newly formed blood vessels in the transplanted sub-mucosa at 2weeks after transplantation. Blood vessels were significantly observed in the MSC sheet group compared to in the control group and MSC intravenous injection group (106±9.6 compared with 40±5.3 and 62±10.2 vessels/mm(2), respectively). These results suggest that allogeneic MSC sheet transplantation is a promising alternative approach for treating BRONJ. Bisphosphonates are frequently used to treat osteoporosis, bone metastasis of various cancers, and other diseases. However, bisphosphonate related-osteonecrosis of the jaw (BRONJ) is an intractable disease because it often recurs after surgery or is exacerbated following conservative treatment. Therefore, an alternative approach for treating BRONJ is needed. In this study, we developed a bone marrow-derived multipotent mesenchymal stromal cell (MSC) sheet to treat BRONJ and investigated the effect of MSC sheet transplantation in a rat model of BRONJ-like disease. The MSC sheet transplantation group showed wound healing in most cases, while only minimal healing was observed in the control group and MSC intravenous injection group. Our results suggest that the MSC sheet is a promising alternative approach for the treatment of BRONJ. Copyright © 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

A growing Leaf as a Sheet of an Active Solid

NASA Astrophysics Data System (ADS)

Sharon, Eran

A growing leaf is a thin sheet of active solid, which expands while obeying the laws of mechanics. The effective rheology of this active solid is nontrivial, allowing the leaf to increase its area by orders of magnitude, keeping its ''proper'' geometry. The questions of what the characteristics of the leaf growth field are and how it is regulated without any central ''headquarter'' are still open. I will present measurements of natural leaf growth with high time and space resolution. These show that the growth is a highly fluctuating process in both time and space. We suggest that the entire statistics of the growth field, not just its averages contain information important for the understanding of growth regulation. In another set of experiments we measure the effect of mechanical stress on deformation and growth. The measured effective rheology is viscoelastic with time varying parameters, indicating remodeling of the tissue in response to extended application of mechanical stress.

Numerical Estimation of the Curvature of Biological Surfaces

NASA Technical Reports Server (NTRS)

Todd, P. H.

1985-01-01

Many biological systems may profitably be studied as surface phenomena. A model consisting of isotropic growth of a curved surface from a flat sheet is assumed. With such a model, the Gaussian curvature of the final surface determines whether growth rate of the surface is subharmonic or superharmonic. These properties correspond to notions of convexity and concavity, and thus to local excess growth and local deficiency of growth. In biological models where the major factors controlling surface growth are intrinsic to the surface, researchers thus gained from geometrical study information on the differential growth undergone by the surface. These ideas were applied to an analysis of the folding of the cerebral cortex, a geometrically rather complex surface growth. A numerical surface curvature technique based on an approximation to the Dupin indicatrix of the surface was developed. A metric for comparing curvature estimates is introduced, and considerable numerical testing indicated the reliability of this technique.

Streaming sausage, kink and tearing instabilities in a current sheet with applications to the earth's magnetotail

NASA Technical Reports Server (NTRS)

Lee, L. C.; Wang, S.; Wei, C. Q.; Tsurutani, B. T.

1988-01-01

This paper investigates the growth rates and eigenmode structures of the streaming sausage, kink, and tearing instabilities in a current sheet with a super-Alfvenic flow. The growth rates and eigenmode structures are first considered in the ideal incompressible limit by using a four-layer model, as well as a more realistic case in which all plasma parameters and the magnetic field vary continuously along the direction perpendicular to the magnetic field and plasma flow. An initial-value method is applied to obtain the growth rate and eigenmode profiles of the fastest growing mode, which is either the sausage mode or kink mode. It is shown that, in the earth's magnetotail, where super-Alfvenic plasma flows are observed in the plasma sheet and the ratio between the plasma and magnetic pressures far away from the current layer is about 0.1-0.3 in the lobes, the streaming sausage and streaming tearing instabilities, but not kink modes, are likely to occur.

Fact Sheet on Avoiding Indoor Air Quality Problems During Flood Cleanup

EPA Pesticide Factsheets

This fact sheet discusses problems caused by microbial growth, and other effects of flooding, on indoor air quality and the steps you can take to lessen these effects. This focuses on residential flood cleanup, but it applies to other building types.

Summary of flat-plate solar array project documentation. Abstracts of published documents, 1975 to June 1982

NASA Technical Reports Server (NTRS)

1982-01-01

Technologies that will enable the private sector to manufacture and widely use photovoltaic systems for the generation of electricity in residential, commercial, industrial, and government applications at a cost per watt that is competitive with other means is investigated. Silicon refinement processes, advanced silicon sheet growth techniques, solar cell development, encapsulation, automated fabrication process technology, advanced module/array design, and module/array test and evaluation techniques are developed.

An Experimental Study of Fatigue Crack Growth in Aluminum Sheet Subjected to Combined Bending and Membrane Stresses

NASA Technical Reports Server (NTRS)

Phillips, Edward P.

1997-01-01

An experimental study was conducted to determine the effects of combined bending and membrane cyclic stresses on the fatigue crack growth behavior of aluminum sheet material. The materials used in the tests were 0.040-in.- thick 2024-T3 alclad and 0.090-in.-thick 2024-T3 bare sheet. In the tests, the membrane stresses were applied as a constant amplitude loading at a stress ratio (minimum to maximum stress) of 0.02, and the bending stresses were applied as a constant amplitude deflection in phase with the membrane stresses. Tests were conducted at ratios of bending to membrane stresses (B/M) of 0, 0.75, and 1.50. The general trends of the results were for larger effects of bending for the higher B/M ratios, the lower membrane stresses, and the thicker material. The addition of cyclic bending stresses to a test with cyclic membrane stresses had only a small effect on the growth rates of through-thickness cracks in the thin material, but had a significant effect on the crack growth rates of through-thickness cracks in the thick material. Adding bending stresses to a test had the most effect on the initiation and early growth of cracks and had less effect on the growth of long through-thickness cracks.

Kelvin-Helmholtz instability of stratified jets.

NASA Astrophysics Data System (ADS)

Hanasz, M.; Sol, H.

1996-11-01

We investigate the Kelvin-Helmholtz instability of stratified jets. The internal component (core) is made of a relativistic gas moving with a relativistic bulk speed. The second component (sheath or envelope) flows between the core and external gas with a nonrelativistic speed. Such a two-component jet describes a variety of possible astrophysical jet configurations like e.g. (1) a relativistic electron-positron beam penetrating a classical electron-proton disc wind or (2) a beam-cocoon structure. We perform a linear stability analysis of such a configuration in the hydrodynamic, plane-parallel, vortex-sheet approximation. The obtained solutions of the dispersion relation show very apparent differences with respect to the single-jet solutions. Due to the reflection of sound waves at the boundary between sheet and external gas, the growth rate as a function of wavenumber presents a specific oscillation pattern. Overdense sheets can slow down the growth rate and contribute to stabilize the configuration. Moreover, we obtain the result that even for relatively small sheet widths the properties of sheet start to dominate the jet dynamics. Such effects could have important astrophysical implications, for instance on the origin of the dichotomy between radio-loud and radio-quiet objects.

Intermittent magnetic reconnection in TS-3 merging experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ono, Y.; Hayashi, Y.; Ii, T.

2011-11-15

Ejection of current sheet with plasma mass causes impulsive and intermittent magnetic reconnection in the TS-3 spherical tokamak (ST) merging experiment. Under high guide toroidal field, the sheet resistivity is almost classical due to the sheet thickness much longer than the ion gyroradius. Large inflow flux and low current-sheet resistivity result in flux and plasma pileup followed by rapid growth of the current sheet. When the pileup exceeds a critical limit, the sheet is ejected mechanically from the squeezed X-point area. The reconnection (outflow) speed is slow during the flux/plasma pileup and is fast during the ejection, suggesting that intermittentmore » reconnection similar to the solar flare increases the averaged reconnection speed. These transient effects enable the merging tokamaks to have the fast reconnection as well as the high-power reconnection heating, even when their current-sheet resistivity is low under high guide field.« less

Ultraviolet photodetectors based on ZnO sheets: The effect of sheet size on photoresponse properties

NASA Astrophysics Data System (ADS)

Ghasempour Ardakani, Abbas; Pazoki, Meysam; Mahdavi, Seyed Mohammad; Bahrampour, Ali Reza; Taghavinia, Nima

2012-05-01

In this work, ultraviolet photodetectors based on electrodeposited ZnO sheet thin films were fabricated on a glass substrate. Before electrodeposition, a thin buffer layer of ZnO was deposited on the glass by pulsed laser deposition method. This layer not only acted as a nucleation site for ZnO sheet growth, but also made it possible to use cheap glass substrate instead of conventional fluorine-doped tin oxide (FTO) substrate. Our results showed that photoresponse properties of the photodetectors strongly depend on the sheet sizes. The smaller sheets exhibited enhanced photosensitivity, shortened fall times and decreased gain compared to larger ones. We showed that photodetectors based on ZnO sheets have a faster response than ones based on polycrystalline films. It was also shown that even less response time could be obtained by using comb-like electrodes instead of two-electrode.

Preparation of high bioactivity multilayered bone-marrow mesenchymal stem cell sheets for myocardial infarction using a 3D-dynamic system.

PubMed

Wang, Yingwei; Zhang, Jianhua; Qin, Zixi; Fan, Zepei; Lu, Cheng; Chen, Baoxin; Zhao, Jupeng; Li, Xiaojuan; Xiao, Fei; Lin, Xi; Wu, Zheng

2018-05-01

Cell sheet techniques offer a promising future for myocardial infarction (MI) therapy; however, insufficient nutrition supply remains the major limitation in maintaining stem cell bioactivity in vitro. In order to enhance cell sheet mechanical strength and bioactivity, a decellularized porcine pericardium (DPP) scaffold was prepared by the phospholipase A2 method, and aspartic acid was used as a spacer arm to improve the vascular endothelial growth factor crosslink efficiency on the DPP scaffold. Based on this scaffold, multilayered bone marrow mesenchymal stem cell sheets were rapidly constructed, using RAD16-I peptide hydrogel as a temporary 3D scaffold, and cell sheets were cultured in either the 3D-dynamic system (DCcs) or the traditional static condition (SCcs). The multilayered structure, stem cell bioactivity, and ultrastructure of DCcs and SCcs were assessed. The DCcs exhibited lower apoptosis, lower differentiation, and an improved paracrine effect after a 48 h culture in vitro compared to the SCcs. Four groups were set to evaluate the cell sheet effect in rat MI model: sham group, MI control group, DCcs group, and SCcs group. The DCcs group improved cardiac function and decreased the infarcted area compared to the MI control group, while no significant improvements were observed in the SCcs group. Improved cell survival, angiogenesis, and Sca-1 + cell and c-kit + cell amounts were observed in the DCcs group. In conclusion, the DCcs maintained higher stem cell bioactivity by using the 3D-dynamic system to provide sufficient nutrition, and transplanting DCcs significantly improved the cardiac function and angiogenesis. This study provides an efficient method to prepare vascular endothelial growth factor covalent decellularized pericardium scaffold with aspartic acid, and a multilayered bone marrow mesenchymal stem cell (BMSC) sheet is constructed on it using a 3D-dynamic system. The dynamic nutrition supply showed a significant benefit on BMSC bioactivity in vitro, including decreasing cell apoptosis, reducing stem cell differentiation, and improving growth factor secretion. These favorable bioactivity improved BMSC survival, angiogenesis, and cardiac function of the infarcted myocardium. The study highlights the importance of dynamic nutrition supply on maintaining stem cell bioactivity within cell sheet, and it stresses the necessity and significance of setting a standard for assessing cell sheet products before transplantation in the future application. Copyright © 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Insolation-driven 100,000-year glacial cycles and hysteresis of ice-sheet volume.

PubMed

Abe-Ouchi, Ayako; Saito, Fuyuki; Kawamura, Kenji; Raymo, Maureen E; Okuno, Jun'ichi; Takahashi, Kunio; Blatter, Heinz

2013-08-08

The growth and reduction of Northern Hemisphere ice sheets over the past million years is dominated by an approximately 100,000-year periodicity and a sawtooth pattern (gradual growth and fast termination). Milankovitch theory proposes that summer insolation at high northern latitudes drives the glacial cycles, and statistical tests have demonstrated that the glacial cycles are indeed linked to eccentricity, obliquity and precession cycles. Yet insolation alone cannot explain the strong 100,000-year cycle, suggesting that internal climatic feedbacks may also be at work. Earlier conceptual models, for example, showed that glacial terminations are associated with the build-up of Northern Hemisphere 'excess ice', but the physical mechanisms underpinning the 100,000-year cycle remain unclear. Here we show, using comprehensive climate and ice-sheet models, that insolation and internal feedbacks between the climate, the ice sheets and the lithosphere-asthenosphere system explain the 100,000-year periodicity. The responses of equilibrium states of ice sheets to summer insolation show hysteresis, with the shape and position of the hysteresis loop playing a key part in determining the periodicities of glacial cycles. The hysteresis loop of the North American ice sheet is such that after inception of the ice sheet, its mass balance remains mostly positive through several precession cycles, whose amplitudes decrease towards an eccentricity minimum. The larger the ice sheet grows and extends towards lower latitudes, the smaller is the insolation required to make the mass balance negative. Therefore, once a large ice sheet is established, a moderate increase in insolation is sufficient to trigger a negative mass balance, leading to an almost complete retreat of the ice sheet within several thousand years. This fast retreat is governed mainly by rapid ablation due to the lowered surface elevation resulting from delayed isostatic rebound, which is the lithosphere-asthenosphere response. Carbon dioxide is involved, but is not determinative, in the evolution of the 100,000-year glacial cycles.

Slicing of Silicon into Sheet Material: Silicon Sheet Growth Development for the Large Area Silicon Sheet Task of the Low Cost Silicon Solar Array Project

NASA Technical Reports Server (NTRS)

Fleming, J. R.

1979-01-01

Testing of low cost low suspension power slurry vehicles is presented. Cutting oils are unlikely to work, but a mineral oil with additives should be workable. Two different abrasives were tested. A cheaper silicon carbide from Norton gave excellent results except for excessive kerf loss: the particles were too big. An abrasive treated for lubricity showed no lubricity improvement in mineral oil vehicle. The bounce fixture was tested for the first time under constant cut rate conditions (rather than constant force). Although the cut was not completed before the blades broke, the blade lifetime of thin (100 micrometer) blades was 120 times the lifetime without the fixture. The large prototype saw completed a successful run, producing 90% cutting yield (849 wafers) at 20 wafers/cm. Although inexperience with large numbers of wafers caused cleaning breakage to reduce this yield to 74%, the yield was high enough that the concept of the large saw is proven workable.

Silicon-on ceramic process: Silicon sheet growth and device development for the large-area silicon sheet task of the low-cost solar array project

NASA Technical Reports Server (NTRS)

Grung, B. L.; Heaps, J. D.; Schmit, F. M.; Schuldt, S. B.; Zook, J. D.

1981-01-01

The technical feasibility of producing solar-cell-quality sheet silicon to meet the Department of Energy (DOE) 1986 overall price goal of $0.70/watt was investigated. With the silicon-on-ceramic (SOC) approach, a low-cost ceramic substrate is coated with large-grain polycrystalline silicon by unidirectional solidification of molten silicon. This effort was divided into several areas of investigation in order to most efficiently meet the goals of the program. These areas include: (1) dip-coating; (2) continuous coating designated SCIM-coating, and acronym for Silicon Coating by an Inverted Meniscus (SCIM); (3) material characterization; (4) cell fabrication and evaluation; and (5) theoretical analysis. Both coating approaches were successful in producing thin layers of large grain, solar-cell-quality silicon. The dip-coating approach was initially investigated and considerable effort was given to this technique. The SCIM technique was adopted because of its scale-up potential and its capability to produce more conventiently large areas of SOC.

Slicing of silicon into sheet material: Silicon sheet growth development for the large area silicon sheet task of the Low Cost Silicon Solar Array project

NASA Technical Reports Server (NTRS)

Fleming, J. R.

1978-01-01

The limits of blade tolerance were defined. The standard blades are T-2 thickness tolerance. Good results were obtained by using a slurry fluid consisting of mineral oil and a lubricity additive. Adjustments of the formulation and fine tuning of the cutting process with the new fluid are necessary. Test results and consultation indicate that the blade breakage encountered with water based slurries is unavoidable. Two full capacity (974 wafer) runs were made on the large prototype saw. Both runs resulted in extremely low yield. However, the reasons for the low yield were lack of proper technique rather than problems with machine function. The test on the effect of amount of material etched off of an as-sawn wafer on solar cell efficiency were completed. The results agree with previous work at JPL in that the minimum material removed per side that gives maximum efficiency is on the order of 10 microns.

Silicon Ingot Casting - Heat Exchanger Method Multi-wire Slicing - Fixed Abrasive Slicing Technique. Phase 3 Silicon Sheet Growth Development for the Large Area Sheet Task of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Schmid, F.; Khattak, C. P.

1979-01-01

Several 20 cm diameter silicon ingots, up to 6.3 kg. were cast with good crystallinity. The graphite heat zone can be purified by heating it to high temperatures in vacuum. This is important in reducing costs and purification of large parts. Electroplated wires with 45 um synthetic diamonds and 30 um natural diamonds showed good cutting efficiency and lifetime. During slicing of a 10 cm x 10 cm workpiece, jerky motion occurred in the feed and rocking mechanisms. This problem is corrected and modifications were made to reduce the weight of the bladeheat by 50%.

Sea-level Change during Hothouse, Cool Greenhouse, and Icehouse Worlds

NASA Astrophysics Data System (ADS)

Miller, K. G.; Browning, J. V.; Wright, J. D.

2015-12-01

Comparison of sea level and climate proxies shows fundamentally different causes and responses (periods, amplitudes, rates) for Myr scale sea-level changes in Hothouse, Cool Greenhouse, and Icehouse worlds. Peak warmth of the past 100 million years was achieved in the Hothouse intervals of the Cenomanian-Santonian (ca. 100-80 Ma) and early Eocene (56-50 Ma). Hothouse global average sea level falls of ~15 m are associated with d18O increases that reflect primarily high latitude cooling and may reflect the growth of small ice sheets in elevated regions of Antarctica. However, these purported Hothouse ice sheets are at or below the detection level of the d18O proxy (15 m ≤ 0.15‰), and it is possible that changes in groundwater storage ('limnoeustasy') could have caused these falls. Cool greenhouse (Campanian to Paleocene, middle to late Eocene) sea-level changes of 15-25 m were caused by growth and decay of small (25-35% of modern) ice sheets, pacing sea-level change on an apparent 2.4 Myr long eccentricity cycle, likely modulating 405 and 100 kyr cycles. Icehouse (past 33.8 Myr) sea-level and ice-volume changes were paced by the 1.2 Myr tilt cycle, with alternating states of 41 and 100 kyr dominance. Warm periods in the Icehouse displayed different sea-level responses. During the largely unipolar Icehouse of the Oligocene to early Miocene, the East Antarctic Ice Sheet (EAIS) was not permanently developed, with intervals of large-scale (~40-55 m sea level equivalent) growth and collapse. During peak warmth of the Miocene Climate Optimum (MCO; ~17-15 Ma) ice volume changes were small (generally <20 m) and paced by the 100 kyr cycle. A permanent EAIS developed following 3 middle Miocene d18O increases (14.7, 13.8, and 13.2 Ma) that were largely cooling events associated with <40 m sea-level falls; the subsequent late Miocene EAIS displayed lower amplitude (~20-30 m) sea-level variations. Despite only moderate atmospheric CO2 levels (400±50 ppm), during the peak warmth interval of the Pliocene, sea levels were only 22±10 m above present (most likely 12-22 m) requiring loss of Greenland, West Antarctica, and small part of EAIS (likely the Wilkes Basin).

Growth and nonlinear response of driven water bells

NASA Astrophysics Data System (ADS)

Kolinski, John M.; Aharoni, Hillel; Fineberg, Jay; Sharon, Eran

2017-04-01

A water bell forms when a fluid jet impacts upon a target and separates into a two-dimensional sheet. Depending on the angle of separation from the target, the sheet can curve into a variety of different geometries. We show analytically that harmonic perturbations of water bells have linear wave solutions with geometry-dependent growth. We test the predictions of this model experimentally with a custom target system, and observe growth in agreement with the model below a critical forcing amplitude. Once the critical forcing amplitude is exceeded, a nonlinear transcritical bifurcation occurs; the response amplitude increases linearly with increasing forcing amplitude, albeit with a fundamentally different spatial form, and distinct nodes appear in the amplitude envelope.

Silicon-on-ceramic Process: Silicon Sheet Growth and Device Development for the Large-area Silicon Sheet and Cell Development Tasks of the Low-cost Solar Array Project

NASA Technical Reports Server (NTRS)

Chapman, P. W.; Zook, J. D.; Heaps, J. D.; Grung, B. L.; Koepke, B.; Schuldt, S. B.

1979-01-01

Significant progress is reported in fabricating a 4 sq cm cell having a 10.1 percent conversion efficiency and a 10 sq cm cell having a 9.2 percent conversion efficiency. The continuous (SCIM) coater succeeded in producing a 16 sq cm coating exhibiting unidirectional solidification and large grain size. A layer was grown at 0.2 cm/sec in the experimental coater which was partially dendritic but also contained a large smooth area approximately 100 micron m thick. The dark characteristic measurements of a typical SCC solar cell yield shunt resistance values of 10K ohms and series resistance values and 0.4 ohm. The production dip-coater is operating at over 50 percent yield in terms of good cell quality material. The most recent run yielded 13 good substrates out of 15.

Proceedings of the 21st Project Integration Meeting

NASA Technical Reports Server (NTRS)

1983-01-01

Progress made by the Flat Plate Solar Array Project during the period April 1982 to January 1983 is described. Reports on polysilicon refining, thin film solar cell and module technology development, central station electric utility activities, silicon sheet growth and characteristics, advanced photovoltaic materials, cell and processes research, module technology, environmental isolation, engineering sciences, module performance and failure analysis and project analysis and integration are included.

Light Sheet Tomography (LST) for in situ imaging of plant roots.

PubMed

Yang, Zhengyi; Downie, Helen; Rozbicki, Emil; Dupuy, Lionel X; MacDonald, Michael P

2013-07-15

The production of crops capable of efficient nutrient use is essential for addressing the problem of global food security. The ability of a plant's root system to interact with the soil micro-environment determines how effectively it can extract water and nutrients. In order to assess this ability and develop the fast and cost effective phenotyping techniques which are needed to establish efficient root systems, in situ imaging in soil is required. To date this has not been possible due to the high density of scatterers and absorbers in soil or because other growth substrates do not sufficiently model the heterogeneity of a soil's microenvironment. We present here a new form of light sheet imaging with novel transparent soil containing refractive index matched particles. This imaging method does not rely on fluorescence, but relies solely on scattering from root material. We term this form of imaging Light Sheet Tomography (LST). We have tested LST on a range of materials and plant roots in transparent soil and gel. Due to the low density of root structures, i.e. relatively large spaces between adjacent roots, long-term monitoring of lettuce root development in situ with subsequent quantitative analysis was achieved.

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.

PubMed

Kaucka, Marketa; Zikmund, Tomas; Tesarova, Marketa; Gyllborg, Daniel; Hellander, Andreas; Jaros, Josef; Kaiser, Jozef; Petersen, Julian; Szarowska, Bara; Newton, Phillip T; Dyachuk, Vyacheslav; Li, Lei; Qian, Hong; Johansson, Anne-Sofie; Mishina, Yuji; Currie, Joshua D; Tanaka, Elly M; Erickson, Alek; Dudley, Andrew; Brismar, Hjalmar; Southam, Paul; Coen, Enrico; Chen, Min; Weinstein, Lee S; Hampl, Ales; Arenas, Ernest; Chagin, Andrei S; Fried, Kaj; Adameyko, Igor

2017-04-17

Cartilaginous structures are at the core of embryo growth and shaping before the bone forms. Here we report a novel principle of vertebrate cartilage growth that is based on introducing transversally-oriented clones into pre-existing cartilage. This mechanism of growth uncouples the lateral expansion of curved cartilaginous sheets from the control of cartilage thickness, a process which might be the evolutionary mechanism underlying adaptations of facial shape. In rod-shaped cartilage structures (Meckel, ribs and skeletal elements in developing limbs), the transverse integration of clonal columns determines the well-defined diameter and resulting rod-like morphology. We were able to alter cartilage shape by experimentally manipulating clonal geometries. Using in silico modeling, we discovered that anisotropic proliferation might explain cartilage bending and groove formation at the macro-scale.

Collisionless reconnection in a quasi-neutral sheet near marginal stability

NASA Technical Reports Server (NTRS)

Pritchett, P. L.; Coroniti, F. V.; Pellat, R.; Karimabadi, H.

1989-01-01

Particle simulations are used to investigate the process of collisionless reconnection in a magnetotail configuration which includes a pressure gradient along the tail axis and tail flaring. In the absence of electron stabilization effects, the tearing mode is stabilized when the ion gyrofrequency in the normal field exceeds the growth rate in the corresponding one-dimensional current sheet. The presence of a low-frequency electromagnetic perturbation in the lobes can serve to destabilize a marginally stable current sheet by producing an extended neutral-sheet region which can then undergo reconnection. These results help to explain how X-type neutral lines, such as those associated with the onset of magnetospheric substorms, can be formed in the near-earth plasma sheet.

Current state and future perspectives on coupled ice-sheet - sea-level modelling

NASA Astrophysics Data System (ADS)

de Boer, Bas; Stocchi, Paolo; Whitehouse, Pippa L.; van de Wal, Roderik S. W.

2017-08-01

The interaction between ice-sheet growth and retreat and sea-level change has been an established field of research for many years. However, recent advances in numerical modelling have shed new light on the precise interaction of marine ice sheets with the change in near-field sea level, and the related stability of the grounding line position. Studies using fully coupled ice-sheet - sea-level models have shown that accounting for gravitationally self-consistent sea-level change will act to slow down the retreat and advance of marine ice-sheet grounding lines. Moreover, by simultaneously solving the 'sea-level equation' and modelling ice-sheet flow, coupled models provide a global field of relative sea-level change that is consistent with dynamic changes in ice-sheet extent. In this paper we present an overview of recent advances, possible caveats, methodologies and challenges involved in coupled ice-sheet - sea-level modelling. We conclude by presenting a first-order comparison between a suite of relative sea-level data and output from a coupled ice-sheet - sea-level model.

Advancing the Growth of the U.S. Wind Industry: Federal Incentives, Funding, and Partnership Opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

The U.S. Department of Energy's (DOE's) Wind Energy Technologies Office (WETO) works to accelerate the development and deployment of wind power. The office provides information for researchers, developers, businesses, manufacturers, communities, and others seeking various types of federal assistance available for advancing wind projects. This fact sheet outlines the primary federal incentives for developing and investing in wind power, resources for funding wind power, and opportunities to partner with DOE and other federal agencies on efforts to move the U.S. wind industry forward.

Translating hydrologically-relevant variables from the ice sheet model SICOPOLIS to the Greenland Analog Project hydrologic modeling domain

NASA Astrophysics Data System (ADS)

Vallot, Dorothée; Applegate, Patrick; Pettersson, Rickard

2013-04-01

Projecting future climate and ice sheet development requires sophisticated models and extensive field observations. Given the present state of our knowledge, it is very difficult to say what will happen with certainty. Despite the ongoing increase in atmospheric greenhouse gas concentrations, the possibility that a new ice sheet might form over Scandinavia in the far distant future cannot be excluded. The growth of a new Scandinavian Ice Sheet would have important consequences for buried nuclear waste repositories. The Greenland Analogue Project, initiated by the Swedish Nuclear Fuel and Waste Management Company (SKB), is working to assess the effects of a possible future ice sheet on groundwater flow by studying a constrained domain in Western Greenland by field measurements (including deep bedrock drilling in front of the ice sheet) combined with numerical modeling. To address the needs of the GAP project, we interpolated results from an ensemble of ice sheet model runs to the smaller and more finely resolved modeling domain used in the GAP project's hydrologic modeling. Three runs have been chosen with three fairly different positive degree-day factors among those that reproduced the modern ice margin at the borehole position. The interpolated results describe changes in hydrologically-relevant variables over two time periods, 115 ka to 80 ka, and 20 ka to 1 ka. In the first of these time periods, the ice margin advances over the model domain; in the second time period, the ice margin retreats over the model domain. The spatially-and temporally dependent variables that we treated include the ice thickness, basal melting rate, surface mass balance, basal temperature, basal thermal regime (frozen or thawed), surface temperature, and basal water pressure. The melt flux is also calculated.

Culture-expanded mesenchymal stem cell sheets enhance extraction-site alveolar bone growth: An animal study.

PubMed

Mu, S; Tee, B C; Emam, H; Zhou, Y; Sun, Z

2018-04-06

Impaired bone formation of the buccal alveolar plate after tooth extraction during adolescence increases the difficulty of future implant restoration. This study was undertaken to assess the feasibility and efficacy of transplanting autogenous scaffold-free culture-expanded mesenchymal stem cell (MSC) sheets to the buccal alveolar bone surface to stimulate local bone growth. Mandibular bone marrow was aspirated from 3-month-old pigs (n = 5), from which MSCs were isolated and culture expanded. Triple-layer MSC sheets were then fabricated using temperature-responsive tissue culture plates. One month after bone marrow aspirations, the same pigs underwent bilateral extraction of mandibular primary molars, immediately followed by transplantation of 3 autogenous triple-layer MSC sheets on to the subperiosteal buccal alveolar surface of 1 randomly chosen side. The contralateral side (control) underwent the same periosteal reflection surgery without receiving MSC sheet transplantation. Six weeks later, the animals were killed and specimens from both sides were immediately harvested for radiographic and histological analysis. Buccal alveolar bone thickness, tissue mineral density (TMD), mineral apposition and bone volume fraction (BV/TV) were quantified and compared between the MSC sheet and control sides using paired t-tests. Triple-layer MSC sheets were reliably fabricated and the majority of cells remained vital before transplantation. The thickness of buccal bone tended to increase with MSC sheet transplantation (P = .18), with 4 of 5 animals showing an average of 1.82 ± 0.73 mm thicker bone on the MSC sheet side than the control side. After being normalized by the TMD of intracortical bone, the TMD of surface cortical bone was 0.5-fold higher on the MSC sheet side than the control side (P < .05). Likewise, the BV/TV measurements of the buccal surface region were also 0.4-fold higher on the MSC sheet side than the control side (P < .05) after being normalized by measurements from the intracortical region. Mineral apposition measurements were not different between the 2 sides. Mandibular marrow-derived MSCs can be fabricated into cell sheets and autogenous transplantation of MSC sheets onto the subperiosteal buccal alveolar bone surface at the tooth-extraction site may increase local bone density. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Root-growth-inhibiting sheet

DOEpatents

Burton, Frederick G.; Cataldo, Dominic A.; Cline, John F.; Skiens, W. Eugene; Van Voris, Peter

1993-01-01

In accordance with this invention, a porous sheet material is provided at intervals with bodies of a polymer which contain a 2,6-dinitroaniline. The sheet material is made porous to permit free passage of water. It may be either a perforated sheet or a woven or non-woven textile material. A particularly desirable embodiment is a non-woven fabric of non-biodegradable material. This type of material is known as a "geotextile" and is used for weed control, prevention of erosion on slopes, and other landscaping purposes. In order to obtain a root repelling property, a dinitroaniline is blended with a polymer which is attached to the geotextile or other porous material.

Root-growth-inhibiting sheet

DOEpatents

Burton, F.G.; Cataldo, D.A.; Cline, J.F.; Skiens, W.E.; Van Voris, P.

1993-01-26

In accordance with this invention, a porous sheet material is provided at intervals with bodies of a polymer which contain a 2,6-dinitroaniline. The sheet material is made porous to permit free passage of water. It may be either a perforated sheet or a woven or non-woven textile material. A particularly desirable embodiment is a non-woven fabric of non-biodegradable material. This type of material is known as a geotextile'' and is used for weed control, prevention of erosion on slopes, and other landscaping purposes. In order to obtain a root repelling property, a dinitroaniline is blended with a polymer which is attached to the geotextile or other porous material.

A facile and scalable method to prepare carbon nanotube-grafted-graphene for high performance Li-S battery

NASA Astrophysics Data System (ADS)

Wang, Q. Q.; Huang, J. B.; Li, G. R.; Lin, Z.; Liu, B. H.; Li, Z. P.

2017-01-01

A carbon nanotube-grafted-graphene (CNT-g-Gr) is developed for enhancements of electrical conduction and polysulfide (PS) absorption to improve rate performance and cycleability of lithium-sulfur battery. The CNT-g-Gr is prepared through CNT growth on Ni-deposited graphene sheet which is fabricated via pyrolysis of glucose in a molten salt. The obtained CNT-g-Gr shows much higher specific surface area and PS adsorption capability than graphene. The in-situ formed Ni nanoparticles on graphene sheet not only serve as the catalytic sites for CNT growth, but also function as the anchor-sites for polar PS absorption. The CNT-g-Gr contributes a superb PS adsorption capability arising from graphene and CNT absorbing weakly-polar PS species, and Ni nanoparticles absorbing the species with stronger polarity. The resultant Li-S battery with the CNT-g-Gr shows excellent cycleability and rate performance. A stable discharge capacity of 900 mAh g-1 (with low capacity degradation rate) and a rate capacity of 260 mAh g-1 at 30 C discharge rate have been achieved.

Fabrication and characterization of poly-(ε)-caprolactone and bioactive glass composites for tissue engineering applications.

PubMed

Mohammadkhah, Ali; Marquardt, Laura M; Sakiyama-Elbert, Shelly E; Day, Delbert E; Harkins, Amy B

2015-04-01

Much work has focused on developing synthetic materials that have tailored degradation profiles and physical properties that may prove useful in developing biomaterials for tissue engineering applications. In the present study, three different composite sheets consisting of biodegradable poly-ε-caprolactone (PCL) and varying types of bioactive glass were investigated. The three composites were composed of 50wt.% PCL and (1) 50wt.% 13-93 B3 borate glass particles, (2) 50wt.% 45S5 silicate glass particles, or (3) a blend of 25wt.% 13-93 B3 and 25wt.% 45S5 glass particles. Degradation profiles determined for each composite showed the composite that contained only 13-93 B3 borate glass had a higher degradation rate compared to the composite containing only 45S5 silicate glass. Uniaxial tensile tests were performed on the composites to determine the effect of adding glass to the polymer on mechanical properties. The peak stress of all of the composites was lower than that of PCL alone, but 100% PCL had a higher stiffness when pre-reacted in cell media for 6weeks, whereas composite sheets did not. Finally, to determine whether the composite sheets would maintain neuronal growth, dorsal root ganglia isolated from embryonic chicks were cultured on composite sheets, and neurite outgrowth was measured. The bioactive glass particles added to the composites showed no negative effects on neurite extension, and neurite extension increased on PCL:45S5 PCL:13-93 B3 when pre-reacted in media for 24h. This work shows that composite sheets of PCL and bioactive glass particles provide a flexible biomaterial for neural tissue engineering applications. Copyright © 2015 Elsevier B.V. All rights reserved.

Does a Local B-Minimum Appear in the Tail Current Sheet During a Substorm Growth Phase?

NASA Astrophysics Data System (ADS)

Sergeev, V. A.; Gordeev, E. I.; Merkin, V. G.; Sitnov, M. I.

2018-03-01

Magnetic configurations with dBz/dr > 0 in the midtail current sheet are potentially unstable to various instabilities associated with the explosive substorm onset. Their existence is hard to confirm with observations of magnetospheric spacecraft. Here we use remote sensing by low-altitude spacecraft that measured the loss cone filling rate during electron-rich solar particle event, providing information about magnetic properties of the tail current sheet. We found a latitudinally localized anisotropic 30 keV electron loss cone region embedded inside an extended region of isotropic solar electron precipitation. It was persistently observed for more than 0.5 h during isolated growth phase event by six Polar Operational Environmental Satellites spacecraft, which crossed the premidnight auroral oval. The embedded anisotropic region was observed 1° poleward of the outer radiation belt boundary over 4-5 h wide magnetic local time sector, suggesting a persistent ridge-type Bz2/j maximum in the equatorial plasma sheet at distances 15-20 RE. We discuss infrequent observations of such events taking into account recent results of global magnetohydrodynamic simulations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Velázquez, Daniel; Seibert, Rachel; Spentzouris, Linda

We report on the growth of 1–10 ML films of hexagonal boron nitride (h-BN), also known as white graphene, on fiber-oriented Ag buffer films on SrTiO{sub 3}(001) by pulsed laser deposition. The Ag buffer films of 40 nm thickness were used as substitutes for expensive single crystal metallic substrates. In-situ, reflection high-energy electron diffraction was used to monitor the surface structure of the Ag films and to observe the formation of the characteristic h-BN diffraction pattern. Further evidence of the growth of h-BN was provided by attenuated total reflectance spectroscopy, which showed the characteristic h-BN peaks at ∼780 cm{sup −1} and 1367.4 cm{supmore » −1}. Ex-situ photoelectron spectroscopy showed that the surface of the h-BN films is stoichiometric. The physical structure of the films was confirmed by scanning electron microscopy. The h-BN films grew as large, sub-millimeter sheets with nano- and micro-sheets scattered on the surface. The h-BN sheets can be exfoliated by the micromechanical adhesive tape method. Spectral analysis was performed by energy dispersive spectroscopy in order to identify the h-BN sheets after exfoliation. The use of thin film Ag allows for reduced use of Ag and makes it possible to adjust the surface morphology of the thin film prior to h-BN growth.« less

Pulsed laser deposition of single layer, hexagonal boron nitride (white graphene, h-BN) on fiber-oriented Ag(111)/SrTiO3(001)

NASA Astrophysics Data System (ADS)

Velázquez, Daniel; Seibert, Rachel; Man, Hamdi; Spentzouris, Linda; Terry, Jeff

2016-03-01

We report on the growth of 1-10 ML films of hexagonal boron nitride (h-BN), also known as white graphene, on fiber-oriented Ag buffer films on SrTiO3(001) by pulsed laser deposition. The Ag buffer films of 40 nm thickness were used as substitutes for expensive single crystal metallic substrates. In-situ, reflection high-energy electron diffraction was used to monitor the surface structure of the Ag films and to observe the formation of the characteristic h-BN diffraction pattern. Further evidence of the growth of h-BN was provided by attenuated total reflectance spectroscopy, which showed the characteristic h-BN peaks at ˜780 cm-1 and 1367.4 cm-1. Ex-situ photoelectron spectroscopy showed that the surface of the h-BN films is stoichiometric. The physical structure of the films was confirmed by scanning electron microscopy. The h-BN films grew as large, sub-millimeter sheets with nano- and micro-sheets scattered on the surface. The h-BN sheets can be exfoliated by the micromechanical adhesive tape method. Spectral analysis was performed by energy dispersive spectroscopy in order to identify the h-BN sheets after exfoliation. The use of thin film Ag allows for reduced use of Ag and makes it possible to adjust the surface morphology of the thin film prior to h-BN growth.

The effect of broken stringers on the stress intensity factor for a uniformly stiffened sheet containing a crack

NASA Technical Reports Server (NTRS)

Poe, C. C., Jr.

1973-01-01

A linear elastic stress analysis was made of a centrally cracked sheet stiffened by riveted, uniformly spaced and sized stringers. The stress intensity factor for the sheet and the load concentration factor for the most highly loaded stringer were determined for various numbers of broken stringers. A broken stringer causes the stress intensity factor to be very high when the crack tip is near the broken stringer, but causes little effect when the crack tip extends beyond several intact stringers. A broken stringer also causes an increase in the load concentration factor of the adjacent stringers. The calculated residual strengths and fatigue-crack-growth lives of a stiffened aluminum sheet with a broken stringer were only slightly less than a sheet with all intact stringers, and were still much higher than those of an unstiffened sheet.

LSSA (Low-cost Silicon Solar Array) project

NASA Technical Reports Server (NTRS)

1976-01-01

Methods are explored for economically generating electrical power to meet future requirements. The Low-Cost Silicon Solar Array Project (LSSA) was established to reduce the price of solar arrays by improving manufacturing technology, adapting mass production techniques, and promoting user acceptance. The new manufacturing technology includes the consideration of new silicon refinement processes, silicon sheet growth techniques, encapsulants, and automated assembly production being developed under contract by industries and universities.

Proceedings of the 26th Project Integration Meeting

NASA Technical Reports Server (NTRS)

1986-01-01

Progress made by the Flat-plate Solar Array (FSA) Project is described for the period July 1985 to April 1986. Included are reports on silicon sheet growth and characterization, silicon material, process development, high-efficienty cells, environmental isolation, engineering sciences, and reliability physics. Also included are technical and plenary presentations made at the 26th Project Integration Meeting (PIM) held on April 29 to 30 and May 1, 1986.

Plasmoid Instability in Forming Current Sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Comisso, L.; Lingam, M.; Huang, Y. -M.

The plasmoid instability has revolutionized our understanding of magnetic reconnection in astrophysical environments. By preventing the formation of highly elongated reconnection layers, it is crucial in enabling the rapid energy conversion rates that are characteristic of many astrophysical phenomena. Most previous studies have focused on Sweet–Parker current sheets, which are unattainable in typical astrophysical systems. Here we derive a general set of scaling laws for the plasmoid instability in resistive and visco-resistive current sheets that evolve over time. Our method relies on a principle of least time that enables us to determine the properties of the reconnecting current sheet (aspect ratio and elapsed time) and the plasmoid instability (growth rate, wavenumber, inner layer width) at the end of the linear phase. After this phase the reconnecting current sheet is disrupted and fast reconnection can occur. The scaling laws of the plasmoid instability are not simple power laws, and they depend on the Lundquist number (S), the magnetic Prandtl number (P m), the noise of the system (more » $${\\psi }_{0}$$), the characteristic rate of current sheet evolution ($$1/\\tau $$), and the thinning process. We also demonstrate that previous scalings are inapplicable to the vast majority of astrophysical systems. Furthermore, we explore the implications of the new scaling relations in astrophysical systems such as the solar corona and the interstellar medium. In both of these systems, we show that our scaling laws yield values for the growth rate, wavenumber, and aspect ratio that are much smaller than the Sweet–Parker–based scalings.« less

Plasmoid Instability in Forming Current Sheets

DOE PAGES

Comisso, L.; Lingam, M.; Huang, Y. -M.; ...

2017-11-28

The plasmoid instability has revolutionized our understanding of magnetic reconnection in astrophysical environments. By preventing the formation of highly elongated reconnection layers, it is crucial in enabling the rapid energy conversion rates that are characteristic of many astrophysical phenomena. Most previous studies have focused on Sweet–Parker current sheets, which are unattainable in typical astrophysical systems. Here we derive a general set of scaling laws for the plasmoid instability in resistive and visco-resistive current sheets that evolve over time. Our method relies on a principle of least time that enables us to determine the properties of the reconnecting current sheet (aspect ratio and elapsed time) and the plasmoid instability (growth rate, wavenumber, inner layer width) at the end of the linear phase. After this phase the reconnecting current sheet is disrupted and fast reconnection can occur. The scaling laws of the plasmoid instability are not simple power laws, and they depend on the Lundquist number (S), the magnetic Prandtl number (P m), the noise of the system (more » $${\\psi }_{0}$$), the characteristic rate of current sheet evolution ($$1/\\tau $$), and the thinning process. We also demonstrate that previous scalings are inapplicable to the vast majority of astrophysical systems. Furthermore, we explore the implications of the new scaling relations in astrophysical systems such as the solar corona and the interstellar medium. In both of these systems, we show that our scaling laws yield values for the growth rate, wavenumber, and aspect ratio that are much smaller than the Sweet–Parker–based scalings.« less

A web-based fact sheet series for grandparents raising grandchildren and the professionals who serve them.

PubMed

Brintnall-Peterson, Mary; Poehlmann, Julie; Morgan, Kari; Shlafer, Rebecca

2009-04-01

To develop and evaluate a series of web-based fact sheets for grandparents raising grandchildren. The fact sheets focus on child development issues that grandparents may face when raising their grandchildren. The fact sheets were developed using research on attachment theory, child development, and the needs of grandparents raising grandchildren. The fact sheets can be viewed online or downloaded for free. Evaluation data for the fact sheets were gathered using an online survey. Results of the survey revealed that the fact sheets are used by grandparents and professionals. Respondents reported sharing the fact sheets with others and using them for personal use, in support groups, and as a general agency resource. The fact sheet series is a useful way to reach both grandparents and professionals working with this audience in a variety of settings. Modifications to the fact sheet series are suggested to address additional needs of grandparents raising grandchildren.

a Study of the Impact of Doubling Carbon Dioxide and Solar Radiation Variations on the Climate System.

NASA Astrophysics Data System (ADS)

Chu, Shaoping

The exchange of moisture and heat between the atmosphere and the Earth's surface fundamentally affect the dynamics and thermodynamics of the climate system. In order to trace moisture flow through the climate system and examine its impact on climate, a hydrologic cycle and a land energy balance have been developed and incorporated into a coupled climate-thermodynamic sea ice (CCSI) model. The expanded CCSI model has been tested by comparing computed climate parameters with available observations and GCM modeling results. In general, the expanded model does a good job in simulating the large scale features of the atmospheric circulation and precipitation in both space and time. The expanded model has been used to examine the possibility that increased levels of CO_2 in the atmosphere may induce the growth of Northern Hemisphere ice sheets. Results of the study indicate that if summer ice albedo is high enough, and there is some mechanism for initially maintaining ice through the summer season, then it may be possible to have ice sheet growth under the conditions CO_2 induced warming, mainly the result of decreased summer ice melt in response to the higher land ice albedo, and not an increase in precipitation. The expanded model has also been used to examine the impact of Milankovitch solar radiation variations on the climate system, to study the mechanisms that produce glacial-interglacial cycles, especially with respect to the initiation of ice sheets. The results show the Milankovitch solar radiation variations affect the climate system most in the polar regions with the mean annual surface air temperature varying directly in response to changes in the annually averaged incoming solar radiation. However, the seasonal variations in the surface air temperatures are much more complex with large magnitude variations for brief times during the year. The study indicates that ice sheets may start to grow under the conditions of low insolation that occurred at 25, 70, and 115 kyr BP and a land ice minimum albedo of 0.53, with the largest growth rate at 115 kyr BP, approximately when the current 100 kyr cycle began as observed in the geological record.

On the abrupt growth dynamics of nonlinear resistive tearing mode and the viscosity effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ali, A.; Li, Jiquan, E-mail: lijq@energy.kyoto-u.ac.jp; Kishimoto, Y.

2014-05-15

The nonlinear evolution of the resistive tearing mode exhibits an abrupt growth after an X-point collapse once the magnetic island exceeds a certain critical width Δ′w{sub c} for large instability parameter Δ′, leading to a current sheet formation [N. F. Loureiro et al., Phys. Rev. Lett. 95, 235003 (2005)]. In this work, we investigate the underlying mechanism of the X-point collapse as well as the current sheet formation including the viscosity effects, based on a secondary instability analysis. The secondary instability is excited due to the quasilinear current modification by the zonal current. In particular, it is identified that themore » current peaking effect is plausibly responsible for the onset of the X-point collapse and the current sheet formation, leading to the explosive growth of reconnected flux. In the presence of finite viscosity, the Δ′w{sub c} scaling with the resistivity gets modified. A transition behavior is revealed at P{sub r}≈1 for the viscosity dependence of Δ′w{sub c} and the linear tearing instability. However, the explosive growth seems to be independent of the viscosity in the magnetic Prandtl number P{sub r}<1 regime, while large viscosity plays a strong dissipation role.« less

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb

PubMed Central

Stamataki, Evangelia; Harich, Benjamin; Guignard, Léo; Preibisch, Stephan; Shorte, Spencer; Keller, Philipp J

2018-01-01

During development, coordinated cell behaviors orchestrate tissue and organ morphogenesis. Detailed descriptions of cell lineages and behaviors provide a powerful framework to elucidate the mechanisms of morphogenesis. To study the cellular basis of limb development, we imaged transgenic fluorescently-labeled embryos from the crustacean Parhyale hawaiensis with multi-view light-sheet microscopy at high spatiotemporal resolution over several days of embryogenesis. The cell lineage of outgrowing thoracic limbs was reconstructed at single-cell resolution with new software called Massive Multi-view Tracker (MaMuT). In silico clonal analyses suggested that the early limb primordium becomes subdivided into anterior-posterior and dorsal-ventral compartments whose boundaries intersect at the distal tip of the growing limb. Limb-bud formation is associated with spatial modulation of cell proliferation, while limb elongation is also driven by preferential orientation of cell divisions along the proximal-distal growth axis. Cellular reconstructions were predictive of the expression patterns of limb development genes including the BMP morphogen Decapentaplegic. PMID:29595475

Large-Amplitude Long-Wave Instability of a Supersonic Shear Layer

NASA Technical Reports Server (NTRS)

Messiter, A. F.

1995-01-01

For sufficiently high Mach numbers, small disturbances on a supersonic vortex sheet are known to grow in amplitude because of slow nonlinear wave steepening. Under the same external conditions, linear theory predicts slow growth of long-wave disturbances to a thin supersonic shear layer. An asymptotic formulation is given here which adds nonzero shear-layer thickness to the weakly nonlinear formulation for a vortex sheet. Spatial evolution is considered, for a spatially periodic disturbance having amplitude of the same order, in Reynolds number, as the shear-layer thickness. A quasi-equilibrium inviscid nonlinear critical layer is found, with effects of diffusion and slow growth appearing through nonsecularity condition. Other limiting cases are also considered, in an attempt to determine a relationship between the vortex-sheet limit and the long-wave limit for a thin shear layer; there appear to be three special limits, corresponding to disturbances of different amplitudes at different locations along the shear layer.

Prediction Of Formability In Sheet Metal Forming Processes Using A Local Damage Model

NASA Astrophysics Data System (ADS)

Teixeira, P.; Santos, Abel; César Sá, J.; Andrade Pires, F.; Barata da Rocha, A.

2007-05-01

The formability in sheet metal forming processes is mainly conditioned by ductile fracture resulting from geometric instabilities due to necking and strain localization. The macroscopic collapse associated with ductile failure is a result of internal degradation described throughout metallographic observations by the nucleation, growth and coalescence of voids and micro-cracks. Damage influences and is influenced by plastic deformation and therefore these two dissipative phenomena should be coupled at the constitutive level. In this contribution, Lemaitre's ductile damage model is coupled with Hill's orthotropic plasticity criterion. The coupling between damaging and material behavior is accounted for within the framework of Continuum Damage Mechanics (CDM). The resulting constitutive equations are implemented in the Abaqus/Explicit code, for the prediction of fracture onset in sheet metal forming processes. The damage evolution law takes into account the important effect of micro-crack closure, which dramatically decreases the rate of damage growth under compressive paths.

The role of sediment supply in esker formation and ice tunnel evolution

NASA Astrophysics Data System (ADS)

Burke, Matthew J.; Brennand, Tracy A.; Sjogren, Darren B.

2015-05-01

Meltwater is an important part of the glacier system as it can directly influence ice sheet dynamics. Although it is important that ice sheet models incorporate accurate information about subglacial meltwater processes, the relative inaccessibility of contemporary ice sheet beds makes direct investigation challenging. Former ice sheet beds contain a wealth of meltwater landforms such as eskers that, if accurately interpreted, can provide detailed insight into the hydrology of former ice sheets. Eskers are the casts of ice-walled channels and are a common landform within the footprint of the last Laurentide and Cordilleran Ice Sheets. In south-western Alberta, esker distribution suggests that both water and sediment supply may have been important controls; the longest esker ridge segments are located within meltwater valleys partially filled by glaciofluvial sediments, whereas the shortest esker ridge segments are located in areas dominated by clast-poor till. Through detailed esker ridge planform and crest-type mapping, and near surface geophysics we reveal morpho-sedimentary relationships that suggest esker sedimentation was dynamic, but that esker distribution and architecture were primarily governed by sediment supply. Through comparison of these data with data from eskers elsewhere, we suggest three formative scenarios: 1) where sediment supply and flow powers were high, coarse sediment loads result in rapid deposition, and rates of thermo-mechanical ice tunnel growth is exceeded by the rate of ice tunnel closure due to sediment infilling. High sedimentation rates reduce ice tunnel cross-sectional area, cause an increase in meltwater flow velocity and force ice tunnel growth. Thus, ice tunnel growth is fastest where sedimentation rate is highest; this positive feedback results in a non-uniform ice tunnel geometry, and favours macroform development and non-uniform ridge geometry. 2) Where sediment supply is limited, but flow power high, the rate of sedimentation is less than the rate of thermo-mechanical ice tunnel growth. Here the ice tunnel enlarges faster than it fills with sediment and its evolution is independent of sedimentation, resulting in more uniform ice tunnel geometry. In these cases esker architecture is dominated by extensive vertical accretion of tabular units and ridge geometry is more uniform. 3) Where sediment is truly supply-limited the sedimentation rate is negligible regardless of water supply and, like scenario 2, ice tunnel growth is independent of sediment deposition, forming a relatively uniform ice tunnel (or eroding the bed). Because meltwater flows transport few gravel clasts the ice tunnel is not completely filled with gravel and, instead, saturated and pressurized diamicton or bedrock (if deformable) from beneath the surrounding ice is "squeezed" into the relatively low pressure ice tunnel during waning flow (or after ice tunnel shutdown), resulting in deformation of limited gravels deposited within the ice tunnel and a landform cored with diamicton or deformed bedrock, and with a relatively uniform ridge geometry. Our data demonstrate that an esker map is a minimum map of ice-walled channel location and that continued detailed investigation of morpho-sedimentary relationships is essential to gaining a complete picture of esker forming processes. Validating the morpho-sedimentary relationships identified in south-western Alberta (and other areas) with a larger data set may allow improved remote predictive esker mapping over larger areas and inferences to be made about spatial and temporal variations in esker depositional environments and ice tunnel evolution.

Backscatter for Ice Sheet 2 Growth Phase in the Winter 1994 Winter Sea Ice Experiment

NASA Technical Reports Server (NTRS)

Nghiem, S. V.

1996-01-01

None. This is raw data from a data set taken during the CRRELEX94 experiment. The data are polarimetric C-band radar measurements of a saline ice sheet grown in the outdoor Geophysical Research Facility at the Cold Regions Research and Engineering Lab. See references for other descriptions of data.

[Surgical Regeneration Therapy Using Myoblast Sheets for Severe Heart Failure].

PubMed

Sawa, Yoshiki

2017-01-01

Heart failure is a life-threatening disorder worldwide, and the current end-stage therapies for severe heart failure are replacement therapies such as ventricular-assist devices and heart transplantation. Although these therapies have been reported to be useful, there are many issues in terms of the durability, complications, limited donors, adverse effect of continuous administration of immunosuppressive agents, and high costs involved. Recently, regenerative therapy based on genetic, cellular, or tissue engineering techniques has gained attention as a new therapy to overcome the challenges encountered in transplantation medicine. We focused on skeletal myoblasts as the source of progenitor cells for autologous cell transplantation and the cell-sheet technique for site-specific implantation. In vitro studies have reported that myoblast sheets secrete cytoprotective and angiogenic cytokines such as hepatocyte growth factor (HGF). Additionally, in vivo studies using large and small animal models of heart failure, we have shown that myoblast sheets could improve diastolic and systolic performance and enhance angiogenesis and antifibrosis as well as the expression of several cytokines including HGF and vascular endothelial growth factor(VEGF) in the tissues at the transplanted site. Based on the results of these studies, we performed clinical trials using autologous myoblast sheets in ischemic cardiomyopathy (ICM) and dilated cardiomyopathy patients. Some patients showed left ventricular reverse remodeling and improved symptoms and exercise tolerance. Recently, multiple medical institutions including our institution successfully conducted an exploratory, uncontrolled, open-label phase II study in subjects with ICM to validate the efficacy and safety of autologous myoblast sheets. Moreover, as a novel cell source for regenerative medicine, our recent studies demonstrated that induced pluripotent stem cell-derived cardiomyocyte sheets showed electrical and microstructural homogeneity with heart tissue in vitro and in vivo, thus establishing proof of concept in small and large animal models of heart failure.

β-sheet propensity controls the kinetic pathways and morphologies of seeded peptide aggregation

NASA Astrophysics Data System (ADS)

Morriss-Andrews, Alex; Bellesia, Giovanni; Shea, Joan-Emma

2012-10-01

The effect of seeds in templating the morphology of peptide aggregates is examined using molecular dynamics simulations and a coarse-grained peptide representation. Varying the nature of the aggregate seed between β-sheet, amorphous, and β-barrel seeds leads to different aggregation pathways and to morphologically different aggregates. Similar effects are seen by varying the β-sheet propensity of the free peptides. For a fibrillar seed and free peptides of high β-sheet propensity, fibrillar growth occurred by means of direct attachment (without structural rearrangement) of free individual peptides and small ordered oligomers onto the seed. For a fibrillar seed and free peptides of low β-sheet propensity, fibrillar growth occurred through a dock-lock mechanism, in which the free peptides first docked onto the seed, and then locked on, extending and aligning to join the fibril. Amorphous seeds absorbed free peptides into themselves indiscriminately, with any fibrillar rearrangement subsequent to this absorption by means of a condensation-ordering transition. Although the mechanisms observed by varying peptide β-sheet propensity are diverse, the initial pathways can always be broken down into the following steps: (i) the free peptides diffuse in the bulk and attach individually to the seed; (ii) the free peptides diffuse and aggregate among themselves; (iii) the free peptide oligomers collide with the seed; and (iv) the free oligomers merge with the seed and rearrange in a manner dependent on the backbone flexibility of both the free and seed peptides. Our simulations indicate that it is possible to sequester peptides from amorphous aggregates into fibrils, and also that aggregate morphology (and thus cytoxicity) can be controlled by introducing seeds of aggregate-compatible peptides with differing β-sheet propensities into the system.

Ductile Damage and Fatigue Behavior of Semi-Finished Tailored Blanks for Sheet-Bulk Metal Forming Processes

NASA Astrophysics Data System (ADS)

Besserer, Hans-Bernward; Hildenbrand, Philipp; Gerstein, Gregory; Rodman, Dmytro; Nürnberger, Florian; Merklein, Marion; Maier, Hans Jürgen

2016-03-01

To produce parts from sheet metal with thickened functional elements, bulk forming operations can be employed. For this new process class, the term sheet-bulk metal forming has been established recently. Since sheet-bulk metal forming processes such as orbital forming generates triaxial stress and strain states, ductile damage is induced in the form of voids in the microstructure. Typical parts will experience cyclic loads during service, and thus, the influence of ductile damage on the fatigue life of parts manufactured by orbital forming is of interest. Both the formation and growth of voids were characterized following this forming process and then compared to the as-received condition of the ferritic deep drawing steel DC04 chosen for this study. Subsequent to the forming operation, the specimens were fatigued and the evolution of ductile damage and the rearrangement of the dislocation networks occurring during cyclic loading were determined. It was shown, that despite an increased ductile damage due to the forming process, the induced strain hardening has a positive effect on the fatigue life of the material. However, by analyzing the fatigued specimens a development of the ductile damage by an increasing number of voids and a change in the void shape were detected.

Apparatus and method for the horizontal, crucible-free growth of silicon sheet crystals

DOEpatents

Ciszek, Theodore F.

1987-01-01

Apparatus for continuously forming a silicon crystal sheet from a silicon rod in a noncrucible environment. The rod is rotated and fed toward an RF coil in an inert atmosphere so that the upper end of the rod becomes molten and the silicon sheet crystal is pulled therefrom substantially horizontally in a continuous strip. A shorting ring may be provided around the rod to limit the heating to the upper end only. Argon gas can be used to create the inert atmosphere within a suitable closed chamber. By use of this apparatus and method, a substantially defect-free silicon crystal sheet is formed that can be used for microcircuitry chips or solar cells.

Boron supercapacitors

DOE PAGES

Zhan, Cheng; Zhang, Pengfei; Dai, Sheng; ...

2016-11-16

Supercapacitors based on the electric double-layer mechanism use porous carbons or graphene as electrodes. To move beyond this paradigm, we propose boron supercapacitors to leverage two-dimensional (2D) boron sheets’ metallicity and low weight. Six 2D boron sheets from both previous theoretical design and experimental growth are chosen as test electrodes. By applying joint density functional theory (JDFT) to the electrode–electrolyte system, we examine how the 2D boron sheets charge up against applied potential. JDFT predicts that these 2D boron sheets exhibit specific capacitance on the order of 400 F/g, about four times that of graphene. As a result, our workmore » suggests that 2D boron sheets are promising electrodes for supercapacitor applications.« less

Boron supercapacitors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhan, Cheng; Zhang, Pengfei; Dai, Sheng

Supercapacitors based on the electric double-layer mechanism use porous carbons or graphene as electrodes. To move beyond this paradigm, we propose boron supercapacitors to leverage two-dimensional (2D) boron sheets’ metallicity and low weight. Six 2D boron sheets from both previous theoretical design and experimental growth are chosen as test electrodes. By applying joint density functional theory (JDFT) to the electrode–electrolyte system, we examine how the 2D boron sheets charge up against applied potential. JDFT predicts that these 2D boron sheets exhibit specific capacitance on the order of 400 F/g, about four times that of graphene. As a result, our workmore » suggests that 2D boron sheets are promising electrodes for supercapacitor applications.« less

Improving Surface Mass Balance Over Ice Sheets and Snow Depth on Sea Ice

NASA Technical Reports Server (NTRS)

Koenig, Lora Suzanne; Box, Jason; Kurtz, Nathan

2013-01-01

Surface mass balance (SMB) over ice sheets and snow on sea ice (SOSI) are important components of the cryosphere. Large knowledge gaps remain in scientists' abilities to monitor SMB and SOSI, including insufficient measurements and difficulties with satellite retrievals. On ice sheets, snow accumulation is the sole mass gain to SMB, and meltwater runoff can be the dominant single loss factor in extremely warm years such as 2012. SOSI affects the growth and melt cycle of the Earth's polar sea ice cover. The summer of 2012 saw the largest satellite-recorded melt area over the Greenland ice sheet and the smallest satellite-recorded Arctic sea ice extent, making this meeting both timely and relevant.

Extreme energetic particle decreases near geostationary orbit - A manifestation of current diversion within the inner plasma sheet

NASA Technical Reports Server (NTRS)

Baker, D. N.; Mcpherron, R. L.

1990-01-01

A qualitative model of cross-tail current flow is considered. It is suggested that when magnetic reconnection begins, the current effectively flows across the plasma sheet both earthward and tailward of the disruption region near the neutral line. It is shown that an enhanced cross-tail current earthward of this region would thin the plasma sheet substantially due to the magnetic pinch effect. The results explain the very taillike field and extreme particle dropouts often seen late in substorm growth phases.

East Antarctic Ice Sheet fluctuations during the Middle Miocene Climatic Transition inferred from faunal and biogeochemical data on planktonic foraminifera (ODP Hole 747A, Kerguelen Plateau)

USGS Publications Warehouse

Verducci, M.; Foresi, L.M.; Scott, G.H.; ,; Sprovieri, M.; Lirer, F.

2007-01-01

This research focuses on a detailed study of faunal and biogeochemical changes that occurred at ODP Hole 747A in the Kerguelen Plateau region of the Southern Ocean during the middle Miocene (14.8-11.8 Ma). Abundance fluctuations of several planktonic foraminiferal taxa, stable oxygen isotope and Mg/Ca ratios have been integrated as a multi-proxy approach to reach a better understanding of the growth modality and fluctuations of the East Antarctic Ice Sheet (EAIS) during this period. A 7°C decrease in Sea Surface Temperature (SST), an abrupt turnover in the planktonic foraminiferal assemblage, a 1.5‰ shift towards heavier δ18O values (Mi3 event) and a related shift towards heavier seawater δ118O values between 13.9 and 13.7 Ma, are interpreted to reflect rapid surface water cooling and EAIS expansion. Hole 747A data suggest a major change in the variability of the climate system fostered by EAIS expansion between 13.9 and 13.7 Ma. Ice sheet fluctuations were greater during the interval 14.8-13.9 Ma compared with those from 13.7 to 11.8 Ma, whereas the latter interval was characterized by a more stable EAIS. In our opinion, the middle Miocene ice sheet expansion in Antarctica represents a first step towards the development of the modern permanent ice sheet

Characteristics of the aluminum alloy sheets for forming and application examples

NASA Astrophysics Data System (ADS)

Uema, Naoyuki; Asano, Mineo

2013-12-01

In this paper, the characteristics and application examples of aluminum alloy sheets developed for automotive parts by Sumitomo Light Metal are described. For the automotive closure panels (ex., hood, back-door), an Al-Mg-Si alloy sheet having an excellent hemming performance was developed. The cause of the occurrence and the propagation of cracks by bending were considered to be the combined effect of the shear bands formed across several crystal grains and the micro-voids formed around the second phase particles. By reducing the shear band formation during bending by controlling the crystallographic texture, the Al-Mg-Si alloy sheets showed an excellent hemming performance. For the automotive outer panels (ex., roof, fender, trunk-lid), an Al-Mg alloy sheet, which has both a good hot blow formability and excellent surface appearance after hot blow forming was developed, and hot blow forming technology was put to practical use using this developed Al-Mg alloy sheet. For automotive heat insulators, a high ductile Al-Fe alloy sheet was developed. The heat insulator, which integrated several panels, was put into practical use using this developed Al-Fe alloy sheet. The textured sheet was often used as a heat insulator in order to reduce the thickness of the aluminum alloy sheet and obtain good press formability. The new textured sheet, which has both high rigidity and good press formability for heat insulators, was developed by FE analysis.

Thin EFG octagons

NASA Astrophysics Data System (ADS)

Kalejs, J. P.

1994-01-01

Mobil Solar Energy Corporation currently practices a unique crystal growth technology for producing crystalline silicon sheet, which is then cut with lasers into wafers. The wafers are processed into solar cells and incorporated into modules for photovoltaic applications. The silicon sheet is produced using a method known as Edge-defined Film-fed growth (EFG), in the form of hollow eight-sided polygons (octagons) with 10 cm faces. These are grown to lengths of 5 meters and thickness of 300 microns, with continuous melt replenishment, in compact furnaces designed to operate at a high sheet area production area of 135 sq cm/min. The present Photovoltaic Manufacturing Technology (PVMaT) three-year program seeks to advance the manufacturing line capabilities of the Mobil Solar crystal growth and cutting technologies. If successful, these advancements will provide significant reductions in already low silicon raw material usage, improve process productivity, laser cutting throughput and yield, and so lower both individual wafer cost and the cost of module production. This report summarizes the significant technical improvements in EFG technology achieved in Phase 1 of this program. Technical results are reported for each of the three main program areas: (1) thin octagon growth (crystal growth) -- to reduce the thickness of the octagon to an interim goal of 250 microns during Phase 1, with an ultimate goal of achieving 200 micron thicknesses; (2) laser cutting -- to improve the laser cutting process, so as to produce wafers with decreased laser cutting damage at increased wafer throughput rates; and (3) process control and product specification -- to implement advanced strategies in crystal growth process control and productivity designed to increase wafer yields.

Multilayer mounting enables long-term imaging of zebrafish development in a light sheet microscope.

PubMed

Kaufmann, Anna; Mickoleit, Michaela; Weber, Michael; Huisken, Jan

2012-09-01

Light sheet microscopy techniques, such as selective plane illumination microscopy (SPIM), are ideally suited for time-lapse imaging of developmental processes lasting several hours to a few days. The success of this promising technology has mainly been limited by the lack of suitable techniques for mounting fragile samples. Embedding zebrafish embryos in agarose, which is common in conventional confocal microscopy, has resulted in severe growth defects and unreliable results. In this study, we systematically quantified the viability and mobility of zebrafish embryos mounted under more suitable conditions. We found that tubes made of fluorinated ethylene propylene (FEP) filled with low concentrations of agarose or methylcellulose provided an optimal balance between sufficient confinement of the living embryo in a physiological environment over 3 days and optical clarity suitable for fluorescence imaging. We also compared the effect of different concentrations of Tricaine on the development of zebrafish and provide guidelines for its optimal use depending on the application. Our results will make light sheet microscopy techniques applicable to more fields of developmental biology, in particular the multiview long-term imaging of zebrafish embryos and other small organisms. Furthermore, the refinement of sample preparation for in toto and in vivo imaging will promote other emerging optical imaging techniques, such as optical projection tomography (OPT).

Vertex Models of Epithelial Morphogenesis

PubMed Central

Fletcher, Alexander G.; Osterfield, Miriam; Baker, Ruth E.; Shvartsman, Stanislav Y.

2014-01-01

The dynamic behavior of epithelial cell sheets plays a central role during numerous developmental processes. Genetic and imaging studies of epithelial morphogenesis in a wide range of organisms have led to increasingly detailed mechanisms of cell sheet dynamics. Computational models offer a useful means by which to investigate and test these mechanisms, and have played a key role in the study of cell-cell interactions. A variety of modeling approaches can be used to simulate the balance of forces within an epithelial sheet. Vertex models are a class of such models that consider cells as individual objects, approximated by two-dimensional polygons representing cellular interfaces, in which each vertex moves in response to forces due to growth, interfacial tension, and pressure within each cell. Vertex models are used to study cellular processes within epithelia, including cell motility, adhesion, mitosis, and delamination. This review summarizes how vertex models have been used to provide insight into developmental processes and highlights current challenges in this area, including progressing these models from two to three dimensions and developing new tools for model validation. PMID:24896108

Models for mirror symmetry breaking via β-sheet-controlled copolymerization: (i) mass balance and (ii) probabilistic treatment.

PubMed

Blanco, Celia; Hochberg, David

2012-12-06

Experimental mechanisms that yield the growth of homochiral copolymers over their heterochiral counterparts have been advocated by Lahav and co-workers. These chiral amplification mechanisms proceed through racemic β-sheet-controlled polymerization operative in both surface crystallites as well as in solution. We develop two complementary theoretical models for these template-induced desymmetrization processes leading to multicomponent homochiral copolymers. First, assuming reversible β-sheet formation, the equilibrium between the free monomer pool and the polymer strand within the template is assumed. This yields coupled nonlinear mass balance equations whose solutions are used to calculate enantiomeric excesses and average lengths of the homochiral chains formed. The second approach is a probabilistic treatment based on random polymerization. The occlusion probabilities depend on the polymerization activation energies for each monomer species and are proportional to the concentrations of the monomers in solution in the constant pool approximation. The monomer occlusion probabilities are represented geometrically in terms of unit simplexes from which conditions for maximizing or minimizing the likelihood for mirror symmetry breaking can be determined.

Atlantic Water Advection and Ice Sheet-Ocean Feedbacks in the Arctic Ocean During the Last 200 ky

NASA Astrophysics Data System (ADS)

Spielhagen, R. F.; Mackensen, A.; Stein, R. H.

2016-12-01

Earlier work on Arctic deep-sea cores from the eastern Lomonosov Ridge and the Morris Jesup Rise had revealed that large-scale Eurasian ice sheet growth was initiated at times with seasonally open waters in the Arctic Ocean, indicating a role for the ocean in nearby ice sheet development in the last 200 ky. Here we present microfossil and geochemical data from new sediment cores obtained from the western and easternmost Lomonosov Ridge during the PS87 expedition (2014) of RV Polarstern, amended by data from refined analyses of the older cores. They allow to investigate in more detail the feedbacks between Atlantic Water (AW) advection, sea ice, and ice sheets. In all cores, high microfossil abundances are found just below layers rich in iceberg-rafted detritus, supporting the hypothesis of Arctic Ocean moisture supply for the growth of Eurasian ice sheets. On the other hand, the new microfaunal results suggest that the decay of the ice sheets and the enhanced freshwater discharge to the Arctic may have influenced the routing of subsurface AW in the Arctic Ocean, at least during marine isotope (sub)stages (MIS) 5a and 5e. In the early part of these relatively mild climatic intervals, faunal and isotopic data suggest a noticable advection of Atlantic Water, yet of rather low temperature and likely at depths comparable to the modern distribution (i.e., below 150 m) or even deeper. This may be explained by a more southerly position of AW cooling and submergence than today, caused by a thick layer of low saline waters near the surface which stemmed from the slow melting of ice sheet remnants on the Eurasian continent and shelves. In the second half of both MIS 5a and 5e, AW advection was significantly stronger and may have occurred at shallower depths, as indicated by unusually large amounts of small subpolar planktic foraminifers in central Arctic sediments. AW was apparently diverted northward from the Fram Strait and spread eastward along the Lomonosov Ridge. A possible explanation is the persistence of a water mass of similarly high density in the upper Eurasian Basin, possibly replenished by intensive sea ice formation and brine rejection. The results suggest a rather long-lasting influence of continental ice on the Arctic Ocean which led to a current pattern in MIS 5a and 5e significantly different from the Holocene style.

Starting Silicon-Ribbon Growth Automatically

NASA Technical Reports Server (NTRS)

Mchugh, J. P.

1984-01-01

Semiautomatic system starts growth of silicon sheets more reliably than system with purely manual control. Control signals for starting sheetcrystal growth consist of ramps (during which signal changes linearly from one value to another over preset time interval) and soaks (during which signal remains constant). Ramps and soaks for best temperature and pulling speed determined by experimentation.

The Pliocene-Pleistocene transition and the onset of the Northern Hemisphere glacial inception

NASA Astrophysics Data System (ADS)

Robinson, A.; Calov, R.; Ganopolski, A.

2011-12-01

The Pliocene-Pleistocene transition (PPT, ca. 3.3-2.4 Ma BP) marks a shift in the Earth's climate and is believed to coincide with the inception of the Northern Hemisphere (NH) ice sheets. This transition is not only characterized by a gradual reduction in atmospheric CO2 concentration, paleo records also show a strengthening in the amplitude of δ18O data and intensified ice rafted debris deposition in the North Atlantic. Previous modeling studies have demonstrated that the drop in atmospheric CO2 plays an important role in the glaciation of the NH ice sheets, and more specifically, it is considered to be the primary cause of the glaciation of Greenland. Here we apply a novel approach to produce transient simulations of the entire PPT, in order to study the glaciation of Greenland and the NH ice sheets and additionally, to investigate which conditions are necessary for full-scale glaciation. The fully-coupled Earth system model of intermediate complexity CLIMBER-2 is used to explore the effects of a suite of orbital and CO2 forcing scenarios on total NH glaciation. CLIMBER-2 includes low-resolution sub-models of the atmosphere, vegetation, ocean and ice sheets - the latter is designed to simulate the big NH ice sheets with a rather low resolution (and high computational efficiency). As a refinement, the results of the global simulations are then used to force regional simulations of the Greenland Ice Sheet (GIS) using the higher resolution (20 km) regional climate-ice sheet model, REMBO-SICOPOLIS. We present results of transient simulations driven by orbital forcing and several CO2 reduction scenarios that are consistent with best estimates from data for this time period. We discuss the growth and persistence of the NH ice sheets in terms of the forcing and feedbacks involved. Additionally, we present a set of simulations with the growth of the NH ice sheets disabled, in order to quantify the effect the large ice sheets have on global and regional temperature anomalies. By simulating the Greenland Ice Sheet (GIS) in our high resolution coupled global-regional approach, we identify with greater precision, the conditions neccesary for inception of the GIS and link these to global climatic changes.

Antarctic glaciation caused ocean circulation changes at the Eocene-Oligocene transition

NASA Astrophysics Data System (ADS)

Goldner, A.; Herold, N.; Huber, M.

2014-07-01

Two main hypotheses compete to explain global cooling and the abrupt growth of the Antarctic ice sheet across the Eocene-Oligocene transition about 34 million years ago: thermal isolation of Antarctica due to southern ocean gateway opening, and declining atmospheric CO2 (refs 5, 6). Increases in ocean thermal stratification and circulation in proxies across the Eocene-Oligocene transition have been interpreted as a unique signature of gateway opening, but at present both mechanisms remain possible. Here, using a coupled ocean-atmosphere model, we show that the rise of Antarctic glaciation, rather than altered palaeogeography, is best able to explain the observed oceanographic changes. We find that growth of the Antarctic ice sheet caused enhanced northward transport of Antarctic intermediate water and invigorated the formation of Antarctic bottom water, fundamentally reorganizing ocean circulation. Conversely, gateway openings had much less impact on ocean thermal stratification and circulation. Our results support available evidence that CO2 drawdown--not gateway opening--caused Antarctic ice sheet growth, and further show that these feedbacks in turn altered ocean circulation. The precise timing and rate of glaciation, and thus its impacts on ocean circulation, reflect the balance between potentially positive feedbacks (increases in sea ice extent and enhanced primary productivity) and negative feedbacks (stronger southward heat transport and localized high-latitude warming). The Antarctic ice sheet had a complex, dynamic role in ocean circulation and heat fluxes during its initiation, and these processes are likely to operate in the future.

Antarctic glaciation caused ocean circulation changes at the Eocene-Oligocene transition.

PubMed

Goldner, A; Herold, N; Huber, M

2014-07-31

Two main hypotheses compete to explain global cooling and the abrupt growth of the Antarctic ice sheet across the Eocene-Oligocene transition about 34 million years ago: thermal isolation of Antarctica due to southern ocean gateway opening, and declining atmospheric CO2 (refs 5, 6). Increases in ocean thermal stratification and circulation in proxies across the Eocene-Oligocene transition have been interpreted as a unique signature of gateway opening, but at present both mechanisms remain possible. Here, using a coupled ocean-atmosphere model, we show that the rise of Antarctic glaciation, rather than altered palaeogeography, is best able to explain the observed oceanographic changes. We find that growth of the Antarctic ice sheet caused enhanced northward transport of Antarctic intermediate water and invigorated the formation of Antarctic bottom water, fundamentally reorganizing ocean circulation. Conversely, gateway openings had much less impact on ocean thermal stratification and circulation. Our results support available evidence that CO2 drawdown--not gateway opening--caused Antarctic ice sheet growth, and further show that these feedbacks in turn altered ocean circulation. The precise timing and rate of glaciation, and thus its impacts on ocean circulation, reflect the balance between potentially positive feedbacks (increases in sea ice extent and enhanced primary productivity) and negative feedbacks (stronger southward heat transport and localized high-latitude warming). The Antarctic ice sheet had a complex, dynamic role in ocean circulation and heat fluxes during its initiation, and these processes are likely to operate in the future.

State Capacity and Resistance in Afghanistan

DTIC Science & Technology

2009-03-01

PRGF )222 of the International Monetary Fund (IMF).223 Facing these self-imposed (internal) and international (external) constraints, budget and...Budget_Policy_Coord_Reporting/Fact _Sheet/Fact_sheet_final_1386.pdf (accessed 19 November 2008). 222 The PRGF provides aid and structural guidance in the...management. See: A Factsheet: The Poverty Reduction and Growth Facility ( PRGF ). (International Monetary Fund, October 2008). On the web: http

Van der Waals epitaxy and photoresponse of hexagonal tellurium nanoplates on flexible mica sheets.

PubMed

Wang, Qisheng; Safdar, Muhammad; Xu, Kai; Mirza, Misbah; Wang, Zhenxing; He, Jun

2014-07-22

Van der Waals epitaxy (vdWE) is of great interest due to its extensive applications in the synthesis of ultrathin two-dimensional (2D) layered materials. However, vdWE of nonlayered functional materials is still not very well documented. Here, although tellurium has a strong tendency to grow into one-dimensional nanoarchitecture due to its chain-like structure, we successfully realize 2D hexagonal tellurium nanoplates on flexible mica sheets via vdWE. Chemically inert mica surface is found to be crucial for the lateral growth of hexagonal tellurium nanoplates since it (1) facilitates the migration of tellurium adatoms along mica surface and (2) allows a large lattice mismatch. Furthermore, 2D tellurium hexagonal nanoplates-based photodetectors are in situ fabricated on flexible mica sheets. Efficient photoresponse is obtained even after bending the device for 100 times, indicating 2D tellurium hexagonal nanoplates-based photodetectors on mica sheets have a great application potential in flexible and wearable optoelectronic devices. We believe the fundamental understanding of vdWE effect on the growth of 2D tellurium hexagonal nanoplate can pave the way toward leveraging vdWE as a useful channel to realize the 2D geometry of other nonlayered materials.

Dip coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Heaps, J. D.; Maciolek, R. B.; Harrison, W. B.; Wolner, H. A.; Hendrickson, G.; Nelson, L. D.

1976-01-01

To date, an experimental dip-coating facility was constructed. Using this facility, relatively thin (1 mm) mullite and alumina substrates were successfully dip-coated with 2.5 - 3.0 ohm-cm, p-type silicon with areas of approximately 20 sq cm. The thickness and grain size of these coatings are influenced by the temperature of the melt and the rate at which the substrate is pulled from the melt. One mullite substrate had dendrite-like crystallites of the order of 1 mm wide and 1 to 2 cm long. Their axes were aligned along the direction of pulling. A large variety of substrate materials were purchased or developed enabling the program to commence a substrate definition evaluation. Due to the insulating nature of the substrate, the bottom layer of the p-n junction may have to be made via the top surface. The feasibility of accomplishing this was demonstrated using single crystal wafers.

Development of tearing instability in a current sheet forming by sheared incompressible flow

NASA Astrophysics Data System (ADS)

Tolman, Elizabeth A.; Loureiro, Nuno F.; Uzdensky, Dmitri A.

2018-02-01

Sweet-Parker current sheets in high Lundquist number plasmas are unstable to tearing, suggesting they will not form in physical systems. Understanding magnetic reconnection thus requires study of the stability of a current sheet as it forms. Formation can occur due to sheared, sub-Alfvénic incompressible flows which narrow the sheet. Standard tearing theory (Furth et al. Phys. Fluids, vol. 6 (4), 1963, pp. 459-484, Rutherford, Phys. Fluids, vol. 16 (11), 1973, pp. 1903-1908, Coppi et al. Fizika Plazmy, vol. 2, 1976, pp. 961-966) is not immediately applicable to such forming sheets for two reasons: first, because the flow introduces terms not present in the standard calculation; second, because the changing equilibrium introduces time dependence to terms which are constant in the standard calculation, complicating the formulation of an eigenvalue problem. This paper adapts standard tearing mode analysis to confront these challenges. In an initial phase when any perturbations are primarily governed by ideal magnetohydrodynamics, a coordinate transformation reveals that the flow compresses and stretches perturbations. A multiple scale formulation describes how linear tearing mode theory (Furth et al. Phys. Fluids, vol. 6 (4), 1963, pp. 459-484, Coppi et al. Fizika Plazmy, vol. 2, 1976, pp. 961-966) can be applied to an equilibrium changing under flow, showing that the flow affects the separable exponential growth only implicitly, by making the standard scalings time dependent. In the nonlinear Rutherford stage, the coordinate transformation shows that standard theory can be adapted by adding to the stationary rates time dependence and an additional term due to the strengthening equilibrium magnetic field. Overall, this understanding supports the use of flow-free scalings with slight modifications to study tearing in a forming sheet.

Pre-vascularization Enhances Therapeutic Effects of Human Mesenchymal Stem Cell Sheets in Full Thickness Skin Wound Repair.

PubMed

Chen, Lei; Xing, Qi; Zhai, Qiyi; Tahtinen, Mitchell; Zhou, Fei; Chen, Lili; Xu, Yingbin; Qi, Shaohai; Zhao, Feng

2017-01-01

Split thickness skin graft (STSG) implantation is one of the standard therapies for full thickness wound repair when full thickness autologous skin grafts (FTG) or skin flap transplants are inapplicable. Combined transplantation of STSG with dermal substitute could enhance its therapeutic effects but the results remain unsatisfactory due to insufficient blood supply at early stages, which causes graft necrosis and fibrosis. Human mesenchymal stem cell (hMSC) sheets are capable of accelerating the wound healing process. We hypothesized that pre-vascularized hMSC sheets would further improve regeneration by providing more versatile angiogenic factors and pre-formed microvessels. In this work, in vitro cultured hMSC cell sheets (HCS) and pre-vascularized hMSC cell sheets (PHCS) were implanted in a rat full thickness skin wound model covered with an autologous STSG. Results demonstrated that the HCS and the PHCS implantations significantly reduced skin contraction and improved cosmetic appearance relative to the STSG control group. The PHCS group experienced the least hemorrhage and necrosis, and lowest inflammatory cell infiltration. It also induced the highest neovascularization in early stages, which established a robust blood micro-circulation to support grafts survival and tissue regeneration. Moreover, the PHCS grafts preserved the largest amount of skin appendages, including hair follicles and sebaceous glands, and developed the smallest epidermal thickness. The superior therapeutic effects seen in PHCS groups were attributed to the elevated presence of growth factors and cytokines in the pre-vascularized cell sheet, which exerted a beneficial paracrine signaling during wound repair. Hence, the strategy of combining STSG with PHCS implantation appears to be a promising approach in regenerative treatment of full thickness skin wounds.

In situ electric properties of Ag films deposited on rough substrates

NASA Astrophysics Data System (ADS)

Zhou, Hong; Yu, Sen-Jiang; Zhang, Yong-Ju; Chen, Miao-Gen; Jiao, Zhi-Wei; Si, Ping-Zhan

2013-01-01

Silver (Ag) films have been deposited on rough substrates (including frosted glass and silicone grease), and for comparison on flat glass, by DC-magnetron sputtering, and their sheet resistances measured in situ during deposition. It is found that the growth of Ag films proceeds through three distinct stages: discontinuous, semi-continuous, and continuous regimes. The sheet resistance on rough substrates jumps in the vicinity of the percolation threshold, whereas the resistance on flat substrates decreases monotonically during deposition. The abnormal in situ electric properties on rough substrates are well explained based on the differences of the growth mechanism and microstructure of Ag films on different substrates.

On the influence of the local maxima of total pressure on the current sheet stability to the kink-like (flapping) mode

NASA Astrophysics Data System (ADS)

Korovinskiy, D. B.; Erkaev, N. V.; Semenov, V. S.; Ivanov, I. B.; Kiehas, S. A.; Ryzhkov, I. I.

2018-02-01

The stability of the Fadeev-like current sheet with respect to transversally propagating kink-like perturbations (flapping mode) is considered in terms of two-dimensional linear magnetohydrodynamic numerical simulations. It is found that the current sheet is stable when the total pressure minimum is located in the sheet center and unstable when the maximum value is reached there. It is shown that an unstable spot of any size enforces the whole sheet to be unstable, though the increment of instability decreases with the reduction of the unstable domain. In unstable sheets, the dispersion curve of instability shows a good match with the double-gradient (DG) model prediction. Here, the typical growth rate (short-wavelength limit) is close to the DG estimate averaged over the unstable region. In stable configurations, the typical frequency matches the maximum DG estimate. The dispersion curve of oscillations demonstrates a local maximum at wavelength ˜0.7 sheet half-width, which is a new feature that is absent in simplified analytical solutions.

(abstract) Variations in Polarimetric Backscatter of Saline Ice Grown Under Diurnal Thermal Cycling Condition

NASA Technical Reports Server (NTRS)

Nghiem, S. V.; Kwok, R.; Yueh, S. H.; Kong, J. A.; Hsu, C. C.; Ding, K. H.

1995-01-01

An experiment was carried out in January 1994 at the Geophysical Research Facility in the Cold Regions Research and Engineering Laboratory. To investigate effects on polarimetric scattering signatures of sea ice growth under diurnal temperature variations, an ice sheet was grown for 2.5 days for the thickness of 10 cm and a polarimetric radar operating at C-band was used to obtain backscattering data in conjunction with ice-characterization measurements. The ice sheet was grown in the late morning of January 19, 1994. The initial growth rate was slow due to high insolation and temperature. As the air temperature dropped during the night, the growth rate increased significantly. The air temperature changed drastically from about -10(deg)C to -35(deg)C between day and night. The temperature cycle was repeated during the next day and the growth rate varied in the same manner. The surface of the ice was partially covered by frost flowers and the areal coverage increased as the ice became thicker. Throughout the ice growth duration of 2.5 days, polarimetric backscatter data were collected at roughly every centimeter of ice growth. For each set of radar measurements of saline ice, a set of calibration measurements was carried out with trihedrial corner reflectors and a metallic sphere. Measured polarimetric backscattering coefficients of the ice sheet reveal a strong correlation between radar data and temperature variations. As the temperature increased (decreased), the backscatter increased (decreased) correspondingly. From the ice-characterization data, temperatures of the air, at the ice-air interface, and in the ice layer had the same variation trend. Another interesting experimental observation is that the salinity measured as a function of ice depth from a sample of 10-cm thich ice indicated that the salinity variations had a similar cycle as the temperature; i.e., the salinity profile recorded the history of the temperature variations. Characterization data of the ice sheet are used in a theoretical model for scattering from saline ice with frost cover to explain the observed polarimetric signatures.

Impinging jets atomization

NASA Technical Reports Server (NTRS)

Ibrahim, E. A.; Przekwas, A. J.

1991-01-01

An analysis of the characteristics of the spray produced by an impinging-jet injector is presented. Predictions of the spray droplet size and distribution are obtained through studying the formation and disintegration of the liquid sheet formed by the impact of two cylindrical jets of the same diameter and momentum. Two breakup regimes of the sheet are considered depending on Weber number, with transition occurring at Weber numbers between 500 and 2000. In the lower Weber number regime, the breakup is due to Taylor cardioidal waves, while at Weber number higher than 2000, the sheet disintegration is by the growth of Kelvin-Helmholtz instability waves. Theoretical expressions to predict the sheet thickness and shape are derived for the low Weber number breakup regime. An existing mathematical analysis of Kelvin-Helmholtz instability of radially moving liquid sheets is adopted in the predictions of resultant drop sizes by sheet breakup at Weber numbers greater than 2000. Comparisons of present theoretical results with experimental measurements and empirical correlations reported in the literature reveal favorable agreement.

Modeling of subglacial hydrological development following rapid supraglacial lake drainage.

PubMed

Dow, C F; Kulessa, B; Rutt, I C; Tsai, V C; Pimentel, S; Doyle, S H; van As, D; Lindbäck, K; Pettersson, R; Jones, G A; Hubbard, A

2015-06-01

The rapid drainage of supraglacial lakes injects substantial volumes of water to the bed of the Greenland ice sheet over short timescales. The effect of these water pulses on the development of basal hydrological systems is largely unknown. To address this, we develop a lake drainage model incorporating both (1) a subglacial radial flux element driven by elastic hydraulic jacking and (2) downstream drainage through a linked channelized and distributed system. Here we present the model and examine whether substantial, efficient subglacial channels can form during or following lake drainage events and their effect on the water pressure in the surrounding distributed system. We force the model with field data from a lake drainage site, 70 km from the terminus of Russell Glacier in West Greenland. The model outputs suggest that efficient subglacial channels do not readily form in the vicinity of the lake during rapid drainage and instead water is evacuated primarily by a transient turbulent sheet and the distributed system. Following lake drainage, channels grow but are not large enough to reduce the water pressure in the surrounding distributed system, unless preexisting channels are present throughout the domain. Our results have implications for the analysis of subglacial hydrological systems in regions where rapid lake drainage provides the primary mechanism for surface-to-bed connections. Model for subglacial hydrological analysis of rapid lake drainage eventsLimited subglacial channel growth during and following rapid lake drainagePersistence of distributed drainage in inland areas where channel growth is limited.

Modeling of subglacial hydrological development following rapid supraglacial lake drainage

PubMed Central

Dow, C F; Kulessa, B; Rutt, I C; Tsai, V C; Pimentel, S; Doyle, S H; van As, D; Lindbäck, K; Pettersson, R; Jones, G A; Hubbard, A

2015-01-01

The rapid drainage of supraglacial lakes injects substantial volumes of water to the bed of the Greenland ice sheet over short timescales. The effect of these water pulses on the development of basal hydrological systems is largely unknown. To address this, we develop a lake drainage model incorporating both (1) a subglacial radial flux element driven by elastic hydraulic jacking and (2) downstream drainage through a linked channelized and distributed system. Here we present the model and examine whether substantial, efficient subglacial channels can form during or following lake drainage events and their effect on the water pressure in the surrounding distributed system. We force the model with field data from a lake drainage site, 70 km from the terminus of Russell Glacier in West Greenland. The model outputs suggest that efficient subglacial channels do not readily form in the vicinity of the lake during rapid drainage and instead water is evacuated primarily by a transient turbulent sheet and the distributed system. Following lake drainage, channels grow but are not large enough to reduce the water pressure in the surrounding distributed system, unless preexisting channels are present throughout the domain. Our results have implications for the analysis of subglacial hydrological systems in regions where rapid lake drainage provides the primary mechanism for surface-to-bed connections. Key Points Model for subglacial hydrological analysis of rapid lake drainage events Limited subglacial channel growth during and following rapid lake drainage Persistence of distributed drainage in inland areas where channel growth is limited PMID:26640746

Silicon Ingot Casting - Heat Exchanger Method (HEM). Multi-Wire Slicing - Fixed Abrasive Slicing Technique (Fast). Phase 4 Silicon Sheet Growth Development for the Large Area Sheet Task of the Low-Cost Solar Array Project

NASA Technical Reports Server (NTRS)

Schmid, F.

1981-01-01

The crystallinity of large HEM silicon ingots as a function of heat flow conditions is investigated. A balanced heat flow at the bottom of the ingot restricts spurious nucleation to the edge of the melted-back seed in contact with the crucible. Homogeneous resistivity distribution over all the ingot has been achieved. The positioning of diamonds electroplated on wirepacks used to slice silicon crystals is considered. The electroplating of diamonds on only the cutting edge is described and the improved slicing performance of these wires evaluated. An economic analysis of value added costs of HEM ingot casting and band saw sectioning indicates the projected add on cost of HEM is well below the 1986 allocation.

Apparatus and method for the horizontal, crucible-free growth of silicon sheet crystals

DOEpatents

Ciszek, T.F.

1984-09-12

Apparatus is provided for continuously forming a silicon crystal sheet from a silicon rod in a non-crucible environment. The rod is rotated and fed toward an RF coil in an inert atmosphere so that the upper end of the rod becomes molten and the silicon sheet crystal is pulled therefrom substantially horizontally in a continuous strip. A shorting ring may be provided around the rod to limit the heating to the upper end only. Argon gas can be used to create the inert atmosphere within a suitable closed chamber. By use of this apparatus and method, a substantially defect-free silicon crystal sheet is formed which can be used for micro-circuitry chips or solar cells.

Fabrication and convergent X-ray nanobeam diffraction characterization of submicron-thickness SrTiO 3 crystalline sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tilka, J. A.; Park, J.; Sampson, K. C.

The creation of thin SrTiO3 crystals from (001)-oriented SrTiO3 bulk single crystals using focused ion beam milling techniques yields sheets with submicron thickness and arbitrary orientation within the (001) plane. Synchrotron x-ray nanodiffraction rocking curve widths of these SrTiO3 sheets are less than 0.02 degrees, less than a factor of two larger than bulk SrTiO3, making these crystals suitable substrates for epitaxial thin film growth. The change in the rocking curve width is sufficiently small that we deduce that dislocations are not introduced into the SrTiO3 sheets. Observed lattice distortions are consistent with a low concentration of point defects.

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

PubMed Central

Kaucka, Marketa; Zikmund, Tomas; Tesarova, Marketa; Gyllborg, Daniel; Hellander, Andreas; Jaros, Josef; Kaiser, Jozef; Petersen, Julian; Szarowska, Bara; Newton, Phillip T; Dyachuk, Vyacheslav; Li, Lei; Qian, Hong; Johansson, Anne-Sofie; Mishina, Yuji; Currie, Joshua D; Tanaka, Elly M; Erickson, Alek; Dudley, Andrew; Brismar, Hjalmar; Southam, Paul; Coen, Enrico; Chen, Min; Weinstein, Lee S; Hampl, Ales; Arenas, Ernest; Chagin, Andrei S; Fried, Kaj; Adameyko, Igor

2017-01-01

Cartilaginous structures are at the core of embryo growth and shaping before the bone forms. Here we report a novel principle of vertebrate cartilage growth that is based on introducing transversally-oriented clones into pre-existing cartilage. This mechanism of growth uncouples the lateral expansion of curved cartilaginous sheets from the control of cartilage thickness, a process which might be the evolutionary mechanism underlying adaptations of facial shape. In rod-shaped cartilage structures (Meckel, ribs and skeletal elements in developing limbs), the transverse integration of clonal columns determines the well-defined diameter and resulting rod-like morphology. We were able to alter cartilage shape by experimentally manipulating clonal geometries. Using in silico modeling, we discovered that anisotropic proliferation might explain cartilage bending and groove formation at the macro-scale. DOI: http://dx.doi.org/10.7554/eLife.25902.001 PMID:28414273

Bockron as a Medium of Learning in The Process of Inquiry based Learning to Improve Science Process Skills of Junior High School Students in Growth and Development Concept

NASA Astrophysics Data System (ADS)

Mayasari, D.

2017-02-01

Investigative research on Influence of bockron as a medium of learning in process of inquiry-based learning to the development of science process skills on the concept of growth and development. This research was done in an effort to follow up underdeveloped skills of observing, communicating andconclude on students. This research was conducted using classroom action research (PTK), which consisted of 3 cycles. Cycle 1 students observe differences in growth and development, cycle 2 students measure the growth rate, cycle 3 students observe factors that influence growth and development, In these three cycles is used as a planting medium bocron (bottles and dacron). It involves 8th grade junior high-school students of 14-15 years old as research subjects in six meetings. Indicators of process skill include observation, communication, interpretation and inference. Data is collected through students’ work sheets, written tests and observation. Processing of the data to see N-Gain used Microsoft Excel 2007, and the results showed that an increase in science process skills with a value of medium N-Gain (0,63). Bokron learning medium easily and cheaply obtainable around the students, particularly those in urban areas is quite difficult to get land to be used as aplanting medium. In addition to observation of growth and development, bokron media can also be used to observe the motion in plants. The use bokron as a learning medium can train and develop science process skills, attitude and scientific method also gives students concrete experience of the process of growth and development in plants.

Algae Drive Enhanced Darkening of Bare Ice on the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Stibal, Marek; Box, Jason E.; Cameron, Karen A.; Langen, Peter L.; Yallop, Marian L.; Mottram, Ruth H.; Khan, Alia L.; Molotch, Noah P.; Chrismas, Nathan A. M.; Calı Quaglia, Filippo; Remias, Daniel; Smeets, C. J. P. Paul; van den Broeke, Michiel R.; Ryan, Jonathan C.; Hubbard, Alun; Tranter, Martyn; van As, Dirk; Ahlstrøm, Andreas P.

2017-11-01

Surface ablation of the Greenland ice sheet is amplified by surface darkening caused by light-absorbing impurities such as mineral dust, black carbon, and pigmented microbial cells. We present the first quantitative assessment of the microbial contribution to the ice sheet surface darkening, based on field measurements of surface reflectance and concentrations of light-absorbing impurities, including pigmented algae, during the 2014 melt season in the southwestern part of the ice sheet. The impact of algae on bare ice darkening in the study area was greater than that of nonalgal impurities and yielded a net albedo reduction of 0.038 ± 0.0035 for each algal population doubling. We argue that algal growth is a crucial control of bare ice darkening, and incorporating the algal darkening effect will improve mass balance and sea level projections of the Greenland ice sheet and ice masses elsewhere.

Effect of living cellular sheets on the angiogenic potential of human microvascular endothelial cells.

PubMed

Villar, Cristina C; Zhao, Xiang R; Livi, Carolina B; Cochran, David L

2015-05-01

A fundamental issue limiting the efficacy of surgical approaches designed to correct periodontal mucogingival defects is that new tissues rely on limited sources of blood supply from the adjacent recipient bed. Accordingly, therapies based on tissue engineering that leverage local self-healing potential may represent promising alternatives for the treatment of mucogingival defects by inducing local vascularization. The aim of this study is to evaluate the effect of commercially available living cellular sheets (LCS) on the angiogenic potential of neonatal dermal human microvascular endothelial cells (HMVEC-dNeo). The effect of LCS on HMVEC-dNeo proliferation, migration, capillary tube formation, gene expression, and production of angiogenic factors was evaluated over time. LCS positively influenced HMVEC-dNeo proliferation and migration. Moreover, HMVEC-dNeo incubated with LCS showed transcriptional profiles different from those of untreated cells. Whereas increased expression of angiogenic genes predominated early on in response to LCS, late-phase responses were characterized by up- and downregulation of angiostatic and angiogenic genes. However, this trend was not confirmed at the protein level, as LCS induced increased production of most of the angiogenic factors tested (i.e., epidermal growth factor [EGF], heparin-binding EGF-like growth factor, interleukin 6, angiopoietin, platelet-derived growth factor-BB, placental growth factor, and vascular endothelial growth factor) throughout the investigational period. Finally, although LCS induced HMVEC-dNeo proliferation, migration, and expression of angiogenic factors, additional factors and environmental pressures are likely to be required to promote the development of complex, mesh-like vascular structures. LCS favor initial mechanisms that govern angiogenesis but failed to enhance or accelerate HMVEC-dNeo morphologic transition to complex vascular structures.

Formation and interpretation of eskers beneath retreating ice sheets

NASA Astrophysics Data System (ADS)

Creyts, T. T.; Hewitt, I.

2017-12-01

The retreat of the ice sheets during the Pleistocene left large and spectacular subglacial features exposed. Understanding these features gives us insight into how the ice sheets retreated, how meltwater influenced retreat, and can help inform our understanding of potential future rates of ice sheet retreat. Among these features, eskers, long sinuous ridges primarily composed of clastic sediments, lack a detailed explanation of how surface melt rates and ice sheet retreat rates influence their growth and spatial distribution. Here, we develop a theory for esker formation based on the initial work of Rothlisberger modified for sediment transport and inclusion of surface meltwater forcing. The primary subglacial ingredients include water flow through subglacial tunnels with the addition of mass balances for sediment transport. We show how eskers when water flow slows below a critical stress for sediment motion. This implies that eskers are deposited in a localized region near the snout of the ice sheet. Our findings suggest that very long eskers form sequentially as the ice front retreats. The position of the esker follows the path of the channel mouth through time, which does not necessarily coincide with the instantaneous route of the feeding channel. However, in most cases, we expect those locations to be similar. The role of surface meltwater and the climatology associated with the forcing is crucial to the lateral spacing of the eskers. We predict that high surface melt rates lead to narrower catchments but that the greater extent of the ablation area means that channels are likely larger. At the same time, for a given channel size (and hence sediment flux), the size of a deposited esker depends on a margin retreat rate. Hence, the size of the eskers is related delicately to the balance between surface melt rates and margin retreat rates. We discuss how our theory can be combined with observed esker distributions to infer the relationship between these two rates and help understand the melt history of ice sheets.

Modelling the effects of ice-sheet activity on CO2 outgassing by Icelandic volcanoes

NASA Astrophysics Data System (ADS)

Armitage, J. J.; Ferguson, D.; Petersen, K. D.; Creyts, T. T.

2017-12-01

Glacial cycles may play a significant role in mediating the flux of magmatic CO2 between the Earth's mantle and atmosphere. In Iceland, it is thought that late-Pleistocene deglaciation led to a significant volcanic pulse, evidenced by increased post-glacial lava volumes and changes in melt chemistry consistent with depressurization. Investigating the extent to which glacial activity may have affected volcanic CO2 emissions from Iceland, and crucially over what timescale, requires detailed knowledge of how the magma system responded to the growth and collapse of the ice-sheet before and after the LGM. To investigate this, we coupled a model of magma generation and transport with a history of ice-sheet activity. Our results show that the emplacement and removal of the LGM ice-sheet likely led to two significant pulses of magmatic CO2. The first, and most significant of these, is associated with ice-sheet growth and occurs as the magma system recovers from glacial loading. This recovery happens from the base of the melting region upwards, producing a pulse of CO2 rich magma that is predicted to reach the surface around 20 ka after the loading event, close in time to the LGM. The second peak in CO2 output occurs abruptly following deglaciation as a consequence of increased rates of melt generation and transport in the shallow mantle. Although these post-glacial melts are relatively depleted in CO2, the increase in magma flux leads to a short-lived period of elevated CO2 emissions. Our results therefore suggest a negative feedback, whereby ice-sheet growth produces a delayed pulse of magmatic CO2, which, in addition to increased geothermal heat flux, may contribute towards driving deglaciation, which itself then causes further magmatism and CO2 outgassing. This model is consistent with the seismic structure of the asthenosphere below Iceland, and the established compositional and volumetric trends for sub- and post-glacial volcanism in Iceland. These trends show that the earliest subglacial events involved small volumes of enriched melts, while eruptions that were synchronous with or immediately followed deglaciation involved larger volumes of more depleted melts.

Development of powder metallurgy 2XXX series Al alloy plate and sheet materials for high temperature aircraft structural applications, FY 1983/1984

NASA Technical Reports Server (NTRS)

Chellman, D. J.

1985-01-01

The objective of this investigation is to fabricate and evaluate PM 2124 Al alloy plate and sheet materials according to NASA program goals for damage tolerance and fatigue resistance. Previous research has indicated the outstanding strength-toughness relationship available with PM 2124 Al-Zr modified alloy compositions in extruded product forms. The range of processing conditions was explored in the fabrication of plate and sheet gage materials, as well as the resultant mechanical and metallurgical properties. The PM composition based on Al-3.70 Cu-1.85 Mg-0.20 Mn with 0.60 wt. pct. Zr was selected. Flat rolled material consisting of 0.250 in. thick plate was fabricated using selected thermal mechanical treatments (TMT). The schedule of TMT operations was designed to yield the extreme conditions of grain structure normally encountered in the fabrication of flat rolled products, specifically recrystallized and unrecrystallized. The PM Al alloy plate and sheet materials exhibited improved strength properties at thin gages compared to IM Al alloys, as a consequence of their enhanced ability to inhibit recrystallization and grain growth. In addition, the PM 2124 Al alloys offer much better combinations of strength and toughnessover equivalent IM Al. The alloy microstructures were examined by optical metallographic texture techniques in order to establish the metallurgical basis for these significant property improvements.

Modeling keratinocyte wound healing dynamics: Cell-cell adhesion promotes sustained collective migration.

PubMed

Nardini, John T; Chapnick, Douglas A; Liu, Xuedong; Bortz, David M

2016-07-07

The in vitro migration of keratinocyte cell sheets displays behavioral and biochemical similarities to the in vivo wound healing response of keratinocytes in animal model systems. In both cases, ligand-dependent Epidermal Growth Factor Receptor (EGFR) activation is sufficient to elicit collective cell migration into the wound. Previous mathematical modeling studies of in vitro wound healing assays assume that physical connections between cells have a hindering effect on cell migration, but biological literature suggests a more complicated story. By combining mathematical modeling and experimental observations of collectively migrating sheets of keratinocytes, we investigate the role of cell-cell adhesion during in vitro keratinocyte wound healing assays. We develop and compare two nonlinear diffusion models of the wound healing process in which cell-cell adhesion either hinders or promotes migration. Both models can accurately fit the leading edge propagation of cell sheets during wound healing when using a time-dependent rate of cell-cell adhesion strength. The model that assumes a positive role of cell-cell adhesion on migration, however, is robust to changes in the leading edge definition and yields a qualitatively accurate density profile. Using RNAi for the critical adherens junction protein, α-catenin, we demonstrate that cell sheets with wild type cell-cell adhesion expression maintain migration into the wound longer than cell sheets with decreased cell-cell adhesion expression, which fails to exhibit collective migration. Our modeling and experimental data thus suggest that cell-cell adhesion promotes sustained migration as cells pull neighboring cells into the wound during wound healing. Copyright © 2016 Elsevier Ltd. All rights reserved.

Heterogeneous Amyloid β-Sheet Polymorphs Identified on Hydrogen Bond Promoting Surfaces Using 2D SFG Spectroscopy.

PubMed

Ho, Jia-Jung; Ghosh, Ayanjeet; Zhang, Tianqi O; Zanni, Martin T

2018-02-08

Two-dimensional sum-frequency generation spectroscopy (2D SFG) is used to study the structures of the pentapeptide FGAIL on hydrogen bond promoting surfaces. FGAIL is the most amyloidogenic portion of the human islet amyloid polypeptide (hIAPP or amylin). In the presence of a pure gold surface, FGAIL does not form ordered structures. When the gold is coated with a self-assembled monolayer of mercaptobenzoic acid (MBA), 2D SFG spectra reveal features associated with β-sheets. Also observed are cross peaks between the FGAIL peptides and the carboxylic acid groups of the MBA monolayer, indicating that the peptides are in close contact with the surface headgroups. In the second set of samples, FGAIL peptides chemically ligated to the MBA monolayer also exhibited β-sheet features but with a much simpler spectrum. From simulations of the experiments, we conclude that the hydrogen bond promoting surface catalyzes the formation of both parallel and antiparallel β-sheet structures with several different orientations. When ligated, parallel sheets with only a single orientation are the primary structure. Thus, this hydrogen bond promoting surface creates a heterogeneous distribution of polymorph structures, consistent with a concentration effect that allows nucleation of many different amyloid seeding structures. A single well-defined seed favors one polymorph over the others, showing that the concentrating influence of a membrane can be counterbalanced by factors that favor directed fiber growth. These experiments lay the foundation for the measurement and interpretation of β-sheet structures with heterodyne-detected 2D SFG spectroscopy. The results of this model system suggest that a heterogeneous distribution of polymorphs found in nature are an indication of nonselective amyloid aggregation whereas a narrow distribution of polymorph structures is consistent with a specific protein or lipid interaction that directs fiber growth.

Low cost silicon solar array project large area silicon sheet task: Silicon web process development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Blais, P. D.; Davis, J. R., Jr.

1977-01-01

Growth configurations were developed which produced crystals having low residual stress levels. The properties of a 106 mm diameter round crucible were evaluated and it was found that this design had greatly enhanced temperature fluctuations arising from convection in the melt. Thermal modeling efforts were directed to developing finite element models of the 106 mm round crucible and an elongated susceptor/crucible configuration. Also, the thermal model for the heat loss modes from the dendritic web was examined for guidance in reducing the thermal stress in the web. An economic analysis was prepared to evaluate the silicon web process in relation to price goals.

Rho-guanine nucleotide exchange factors during development

PubMed Central

Mulinari, Shai

2010-01-01

The development of multicellular organisms is associated with extensive rearrangements of tissues and cell sheets. The driving force for these rearrangements is generated mostly by the actin cytoskeleton. In order to permit the reproducible development of a specific body plan, dynamic reorganization of the actin cytoskeleton must be precisely coordinated in space and time. GTP-exchange factors that activate small GTPases of the Rho family play an important role in this process. Here we review the role of this class of cytoskeletal regulators during important developmental processes such as epithelial morphogenesis, cytokinesis, cell migration, cell polarity, neuronal growth cone extension and phagocytosis in different model systems. PMID:21686118

Sheet of osteoblastic cells combined with platelet-rich fibrin improves the formation of bone in critical-size calvarial defects in rabbits.

PubMed

Wang, Zhifa; Hu, Hanqing; Li, Zhijin; Weng, Yanming; Dai, Taiqiang; Zong, Chunlin; Liu, Yanpu; Liu, Bin

2016-04-01

Techniques that use sheets of cells have been successfully used in various types of tissue regeneration, and platelet-rich fibrin (PRF) can be used as a source of growth factors to promote angiogenesis. We have investigated the effects of the combination of PRF and sheets of mesenchymal stem cells (MSC) from bone marrow on the restoration of bone in critical-size calvarial defects in rabbits to find out whether the combination promotes bony healing. Sheets of MSC and PRF were prepared from the same donor. We then implanted the combined MSC and PRF in critical-size calvarial defects in rabbits and assessed bony restoration by microcomputed tomography (microCT) and histological analysis. The results showed that PRF significantly increased bony regeneration at 8 weeks after implantation of sheets of MSC and PRF compared with sheets of MSC alone (p=0.0048). Our results indicate that the combination of sheets of MSC and PRF increases bone regeneration in critical-size calvarial defects in rabbits, and provides a new way to improve skeletal healing. Copyright © 2015 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Enhancement of Strength and Ductility of Mg96Zn2Y2 Rolled Sheet by Controlling Structure and Plastic Deformation

NASA Astrophysics Data System (ADS)

Noda, Masafumi; Kawamura, Yoshihito; Sakurai, Hiroshi; Funami, Kunio

Mg-Zn-Y alloys are well known to possess greatly enhanced strength during plastic deformation because of the presence of kink bands in the LPSO phase and refinement of the grains of the alpha Mg phase. On the other hand, Mg-rare earth (RE) and Mg-Zn-RE alloys with a long period stacking order (LPSO) phase show a high tensile yield strength when subjected to an extrusion process but it is not known whether the LPSO and alpha Mg phases develop during plastic deformation. We examined the effect of the finely dispersed LPSO phase and the alpha Mg phase on the development of high strength in sheets of Mg96Zn2Y2 subjected to a few passes of rolling. The mechanical properties and thermal stability of the alloy were also investigated. The tensile yield strength of rolled sheets of Mg96Zn2Y2 was 360 MPa and its elongation was 5% when the material was subjected to thermomechanically controlled processing at 673 K with a four-pass rolling schedule. However, the tensile yield strength decreased and the elongation increased at annealing temperature of 623 K or above, because of the presence of grain growth in the alpha Mg phase and the restoration of kink bands in the LPSO phase.

Scanning Thin-Sheet Laser Imaging Microscopy Elucidates Details on Mouse Ear Development

PubMed Central

Kopecky, Benjamin; Johnson, Shane; Schmitz, Heather; Santi, Peter; Fritzsch, Bernd

2016-01-01

Background The mammalian inner ear is transformed from a flat placode into a three-dimensional (3D) structure with six sensory epithelia that allow for the perception of sound and both linear and angular acceleration. While hearing and balance problems are typically considered to be adult onset diseases, they may arise as a developmental perturbation to the developing ear. Future prevention of hearing or balance loss requires an understanding of how closely genetic mutations in model organisms reflect the human case, necessitating an objective multidimensional comparison of mouse ears with human ears that have comparable mutations in the same gene. Results Here, we present improved 3D analyses of normal murine ears during embryonic development using optical sections obtained through Thin-Sheet Laser Imaging Microscopy. We chronicle the transformation of an undifferentiated otic vesicle between mouse embryonic day 11.5 to a fully differentiated inner ear at postnatal day 15. Conclusions Our analysis of ear development provides new insights into ear development, enables unique perspectives into the complex development of the ear, and allows for the first full quantification of volumetric and linear aspects of ear growth. Our data provide the framework for future analysis of mutant phenotypes that are currently under-appreciated using only two dimensional renderings. PMID:22271591

Scanning thin-sheet laser imaging microscopy elucidates details on mouse ear development.

PubMed

Kopecky, Benjamin; Johnson, Shane; Schmitz, Heather; Santi, Peter; Fritzsch, Bernd

2012-03-01

The mammalian inner ear is transformed from a flat placode into a three-dimensional (3D) structure with six sensory epithelia that allow for the perception of sound and both linear and angular acceleration. While hearing and balance problems are typically considered to be adult onset diseases, they may arise as a developmental perturbation to the developing ear. Future prevention of hearing or balance loss requires an understanding of how closely genetic mutations in model organisms reflect the human case, necessitating an objective multidimensional comparison of mouse ears with human ears that have comparable mutations in the same gene. Here, we present improved 3D analyses of normal murine ears during embryonic development using optical sections obtained through Thin-Sheet Laser Imaging Microscopy. We chronicle the transformation of an undifferentiated otic vesicle between mouse embryonic day 11.5 to a fully differentiated inner ear at postnatal day 15. Our analysis of ear development provides new insights into ear development, enables unique perspectives into the complex development of the ear, and allows for the first full quantification of volumetric and linear aspects of ear growth. Our data provide the framework for future analysis of mutant phenotypes that are currently under-appreciated using only two dimensional renderings. Copyright © 2012 Wiley Periodicals, Inc.

Test Driven Development of a Parameterized Ice Sheet Component

NASA Astrophysics Data System (ADS)

Clune, T.

2011-12-01

Test driven development (TDD) is a software development methodology that offers many advantages over traditional approaches including reduced development and maintenance costs, improved reliability, and superior design quality. Although TDD is widely accepted in many software communities, the suitability to scientific software is largely undemonstrated and warrants a degree of skepticism. Indeed, numerical algorithms pose several challenges to unit testing in general, and TDD in particular. Among these challenges are the need to have simple, non-redundant closed-form expressions to compare against the results obtained from the implementation as well as realistic error estimates. The necessity for serial and parallel performance raises additional concerns for many scientific applicaitons. In previous work I demonstrated that TDD performed well for the development of a relatively simple numerical model that simulates the growth of snowflakes, but the results were anecdotal and of limited relevance to far more complex software components typical of climate models. This investigation has now been extended by successfully applying TDD to the implementation of a substantial portion of a new parameterized ice sheet component within a full climate model. After a brief introduction to TDD, I will present techniques that address some of the obstacles encountered with numerical algorithms. I will conclude with some quantitative and qualitative comparisons against climate components developed in a more traditional manner.

Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

NASA Astrophysics Data System (ADS)

Rothdiener, Miriam; Hegemann, Miriam; Uynuk-Ool, Tatiana; Walters, Brandan; Papugy, Piruntha; Nguyen, Phong; Claus, Valentin; Seeger, Tanja; Stoeckle, Ulrich; Boehme, Karen A.; Aicher, Wilhelm K.; Stegemann, Jan P.; Hart, Melanie L.; Kurz, Bodo; Klein, Gerd; Rolauffs, Bernd

2016-10-01

Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffness with cyclic stretch would result in a significantly increased expression of SMC markers, compared to non-stretched controls. First, we generated dense collagen type I sheets by mechanically compressing collagen hydrogels. Atomic force microscopy revealed a nanoscale stiffness range known to support myogenic differentiation. Further characterization revealed viscoelasticity and stable biomechanical properties under cyclic stretch with >99% viable adherent human MSC. MSCs on collagen sheets demonstrated a significantly increased mRNA but not protein expression of SMC markers, compared to on culture flasks. However, cyclic stretch of MSCs on collagen sheets significantly increased both mRNA and protein expression of α-smooth muscle actin, transgelin, and calponin versus plastic and non-stretched sheets. Thus, lineage-specific stiffness and cyclic stretch can be applied together for inducing MSC differentiation towards SMCs without the addition of recombinant growth factors or other soluble factors. This represents a novel stimulation method for modulating the phenotype of MSCs towards SMCs that could easily be incorporated into currently available methodologies to obtain a more targeted control of MSC phenotype.

Imaging radar studies of polar ice

NASA Technical Reports Server (NTRS)

Carsey, Frank

1993-01-01

A vugraph format presentation is given. The following topics are discussed: scientific overview, radar data opportunities, sea ice investigations, and ice sheet investigations. The Sea Ice Scientific Objectives are as follows: (1) to estimate globally the surface brine generation, heat flux, and fresh water advection (as ice); (2) to monitor phasing of seasonal melt and freeze events and accurately estimate melt and growth rates; and (3) to develop improved treatment of momentum transfer and ice mechanics in coupled air-sea-ice models.

Analysis of defect structure in silicon. Characterization of SEMIX material. Silicon sheet growth development for the large area silicon sheet task of the low-cost solar array project

NASA Technical Reports Server (NTRS)

Natesh, R.; Stringfellow, G. B.; Virkar, A. V.; Dunn, J.; Guyer, T.

1983-01-01

Statistically significant quantitative structural imperfection measurements were made on samples from ubiquitous crystalline process (UCP) Ingot 5848 - 13C. Important correlation was obtained between defect densities, cell efficiency, and diffusion length. Grain boundary substructure displayed a strong influence on the conversion efficiency of solar cells from Semix material. Quantitative microscopy measurements gave statistically significant information compared to other microanalytical techniques. A surface preparation technique to obtain proper contrast of structural defects suitable for quantimet quantitative image analyzer (QTM) analysis was perfected and is used routinely. The relationships between hole mobility and grain boundary density was determined. Mobility was measured using the van der Pauw technique, and grain boundary density was measured using quantitative microscopy technique. Mobility was found to decrease with increasing grain boundary density.

LSA Large Area Silicon Sheet Task Continuous Czochralski Process Development

NASA Technical Reports Server (NTRS)

Rea, S. N.

1979-01-01

A commercial Czochralski crystal growing furnace was converted to a continuous growth facility by installation of a small, in-situ premelter with attendant silicon storage and transport mechanisms. Using a vertical, cylindrical graphite heater containing a small fused quartz test tube linear from which the molten silicon flowed out the bottom, approximately 83 cm of nominal 5 cm diamter crystal was grown with continuous melt addition furnished by the test tube premelter. High perfection crystal was not obtained, however, due primarily to particulate contamination of the melt. A major contributor to the particulate problem was severe silicon oxide buildup on the premelter which would ultimately drop into the primary melt. Elimination of this oxide buildup will require extensive study and experimentation and the ultimate success of continuous Czochralski depends on a successful solution to this problem. Economically, the continuous Czochralski meets near-term cost goals for silicon sheet material.

Emergent patterns of collective cell migration under tubular confinement.

PubMed

Xi, Wang; Sonam, Surabhi; Beng Saw, Thuan; Ladoux, Benoit; Teck Lim, Chwee

2017-11-15

Collective epithelial behaviors are essential for the development of lumens in organs. However, conventional assays of planar systems fail to replicate cell cohorts of tubular structures that advance in concerted ways on out-of-plane curved and confined surfaces, such as ductal elongation in vivo. Here, we mimic such coordinated tissue migration by forming lumens of epithelial cell sheets inside microtubes of 1-10 cell lengths in diameter. We show that these cell tubes reproduce the physiological apical-basal polarity, and have actin alignment, cell orientation, tissue organization, and migration modes that depend on the extent of tubular confinement and/or curvature. In contrast to flat constraint, the cell sheets in a highly constricted smaller microtube demonstrate slow motion with periodic relaxation, but fast overall movement in large microtubes. Altogether, our findings provide insights into the emerging migratory modes for epithelial migration and growth under tubular confinement, which are reminiscent of the in vivo scenario.

Methods for determining deformation history for chocolate tablet boudinage with fibrous crystals

NASA Astrophysics Data System (ADS)

Casey, M.; Dietrich, D.; Ramsay, J. G.

1983-02-01

Chocolate tablet boudinage with fibrous crystal growths between the boudinaged plates from two localities were studied. In one, from Leytron, Valais, Switzerland, the deformation history was found to be a succession of plane strain increments with the shortening direction perpendicular to the boudinaged sheet and the extension direction showing a progressive change in orientation within the sheet. The incremental and finite strains were evaluated. The other specimen, from Parys Mountain, Anglesey Great Britain, was found to have a more complex history with diachronous break up of the competent layer and flattening strain increments. It was found that under these circumstances the direct graphical methods of determining finite and incremental strains gave inconsistent results. A numerical model was developed which allowed the simulation of chocolate tablet structure with a complex deformation history. The model was applied to the Anglesey specimen and three possible strain histories for this structure were tried.

Silicon Sheet Growth Development for the Large Area Sheet Task of the Low Cost Solar Array Project. Heat Exchanger Method - Ingot Casting Fixed Abrasive Method - Multi-Wire Slicing

NASA Technical Reports Server (NTRS)

Schmid, F.; Khattak, C. P.

1978-01-01

Solar cells fabricated from HEM cast silicon yielded up to 15% conversion efficiencies. This was achieved in spite of using unpurified graphite parts in the HEM furnace and without optimization of material or cell processing parameters. Molybdenum retainers prevented SiC formation and reduced carbon content by 50%. The oxygen content of vacuum cast HEM silicon is lower than typical Czochralski grown silicon. Impregnation of 45 micrometers diamonds into 7.5 micrometers copper sheath showed distortion of the copper layer. However, 12.5 micrometers and 15 micrometers copper sheath can be impregnated with 45 micrometers diamonds to a high concentration. Electroless nickel plating of wires impregnated only in the cutting edge showed nickel concentration around the diamonds. This has the possibility of reducing kerf. The high speed slicer fabricated can achieve higher speed and longer stroke with vibration isolation.

Influence of intermediate annealing on abnormal Goss grain growth in the rolled columnar-grained Fe-Ga-Al alloys

NASA Astrophysics Data System (ADS)

Liu, Yangyang; Li, Jiheng; Gao, Xuexu

2017-08-01

Magnetostrictive Fe82Ga4.5Al13.5 sheets with 0.1 at% NbC were prepared from directional solidified alloys with <0 0 1> preferred orientation. The slabs were hot rolled at 650 °C and warm rolled at 500 °C. Then some warm-rolled sheets were annealed intermediately at 850 °C for 5 min but the others not. After that, all the sheets were cold rolled to a final thickness of ∼0.3 mm. The microstructures, the textures and the distributions of second phase particles in the primary recrystallized samples were investigated. With intermediate annealing, the inhomogeneous microstructure was improved remarkably and strong Goss ({1 1 0}<0 0 1>) and γ-fiber (<1 1 1>//normal direction [ND]) textures were produced in the primary recrystallized samples. But, an evident disadvantage in size and quantity was observed for Goss grains in the primary recrystallized sample without intermediate annealing. After a final annealing, the final textures and magnetostrictions of samples with and without intermediate annealing were characterized. For samples without intermediate annealing, abnormal growth of {1 1 3} grains occurred and deteriorated the magnetostriction. In contrast, abnormal Goss grain growth occurred completely in samples with intermediate annealing and led to saturation magnetostriction as high as 156 ppm.

The substorm loading-unloading cycle as reproduced by community-available global MHD magnetospheric models

NASA Astrophysics Data System (ADS)

Gordeev, Evgeny; Sergeev, Victor; Tsyganenko, Nikolay; Kuznetsova, Maria; Rastaetter, Lutz; Raeder, Joachim; Toth, Gabor; Lyon, John; Merkin, Vyacheslav; Wiltberger, Michael

2017-04-01

In this study we investigate how well the three community-available global MHD models, supported by the Community Coordinated Modeling Center (CCMC NASA), reproduce the global magnetospheric dynamics, including the loading-unloading substorm cycle. We found that in terms of global magnetic flux transport CCMC models display systematically different response to idealized 2-hour north then 2-hour south IMF Bz variation. The LFM model shows a depressed return convection in the tail plasma sheet and high rate of magnetic flux loading into the lobes during the growth phase, as well as enhanced return convection and high unloading rate during the expansion phase, with the amount of loaded/unloaded magnetotail flux and the growth phase duration being the closest to their observed empirical values during isolated substorms. BATSRUS and Open GGCM models exhibit drastically different behavior. In the BATS-R-US model the plasma sheet convection shows a smooth transition to the steady convection regime after the IMF southward turning. In the Open GGCM a weak plasma sheet convection has comparable intensities during both the growth phase and the following slow unloading phase. Our study shows that different CCMC models under the same solar wind conditions (north to south IMF variation) produce essentially different solutions in terms of global magnetospheric convection.

Low Temperature Metal Free Growth of Graphene on Insulating Substrates by Plasma Assisted Chemical Vapor Deposition

PubMed Central

Muñoz, R.; Munuera, C.; Martínez, J. I.; Azpeitia, J.; Gómez-Aleixandre, C.; García-Hernández, M.

2016-01-01

Direct growth of graphene films on dielectric substrates (quartz and silica) is reported, by means of remote electron cyclotron resonance plasma assisted chemical vapor deposition r-(ECR-CVD) at low temperature (650°C). Using a two step deposition process- nucleation and growth- by changing the partial pressure of the gas precursors at constant temperature, mostly monolayer continuous films, with grain sizes up to 500 nm are grown, exhibiting transmittance larger than 92% and sheet resistance as low as 900 Ω·sq-1. The grain size and nucleation density of the resulting graphene sheets can be controlled varying the deposition time and pressure. In additon, first-principles DFT-based calculations have been carried out in order to rationalize the oxygen reduction in the quartz surface experimentally observed. This method is easily scalable and avoids damaging and expensive transfer steps of graphene films, improving compatibility with current fabrication technologies. PMID:28070341

Continuous development of current sheets near and away from magnetic nulls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, Sanjay; Bhattacharyya, R.

2016-04-15

The presented computations compare the strength of current sheets which develop near and away from the magnetic nulls. To ensure the spontaneous generation of current sheets, the computations are performed congruently with Parker's magnetostatic theorem. The simulations evince current sheets near two dimensional and three dimensional magnetic nulls as well as away from them. An important finding of this work is in the demonstration of comparative scaling of peak current density with numerical resolution, for these different types of current sheets. The results document current sheets near two dimensional magnetic nulls to have larger strength while exhibiting a stronger scalingmore » than the current sheets close to three dimensional magnetic nulls or away from any magnetic null. The comparative scaling points to a scenario where the magnetic topology near a developing current sheet is important for energetics of the subsequent reconnection.« less

24 CFR 1710.117 - Cost sheet, signature of Senior Executive Officer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Cost sheet, signature of Senior... REGISTRATION Reporting Requirements § 1710.117 Cost sheet, signature of Senior Executive Officer. (a) Cost... description of our subdivision and development plans. Signature of Senior Executive Officer (2) Cost sheet...

Hierarchical regrowth of flowerlike nanographene sheets on oxygen-plasma-treated carbon nanowalls

NASA Astrophysics Data System (ADS)

Shimoeda, Hironao; Kondo, Hiroki; Ishikawa, Kenji; Hiramatsu, Mineo; Sekine, Makoto; Hori, Masaru

2014-04-01

Cauliflorous nanographene sheets were hierarchically regrown on the spearlike structures of carbon nanowalls (CNWs) produced by O2-plasma etching. The spears on the CNWs acted as a stem for the growth of flowerlike flaky nanographene sheets, where the root of the nanoflower was located at a defect or disordered site. The defects on the graphitic structures were induced by irradiation with oxygen-related radicals and ions in the O2-based plasmas and acted as sites for the nucleation of flowerlike nanographene. The porous carbon nanostructures regrown after O2-plasma treatment have a relatively higher surface area and are thus promising materials for electrochemical applications.

Development of a highly transparent superamphiphobic plastic sheet by nanoparticle and chemical coating.

PubMed

Wong, Ten It; Wang, Hao; Wang, Fuke; Sin, Sau Leng; Quan, Cheng Gen; Wang, Shi Jie; Zhou, Xiaodong

2016-04-01

A highly transparent superamphiphobic plastic sheet was developed. The plastic sheet polymethyl methacrylate (PMMA) was spin-coated on a glass substrate. Synthesized silica nanoparticles were sprayed on PMMA, followed by fluorosilane drop-coating. The results of contact angle measurements show that the developed PMMA sheet has superamphiphobic properties with high advancing contact angles for water (154°), toluene (139°), and silicone oil (132.9°). The amphiphobicity of the plastic sheet can be tuned by the surface coverage of the silica nanoparticles distributed on the PMMA surface. The surface coverage of the nanoparticles on our PMMA sheet is about 20%, and it agrees with our contact angle calculations for the sheet with and without nanoparticles. Copyright © 2016 Elsevier Inc. All rights reserved.

Modelling seasonal meltwater forcing of the velocity of land-terminating margins of the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Koziol, Conrad P.; Arnold, Neil

2018-03-01

Surface runoff at the margin of the Greenland Ice Sheet (GrIS) drains to the ice-sheet bed, leading to enhanced summer ice flow. Ice velocities show a pattern of early summer acceleration followed by mid-summer deceleration due to evolution of the subglacial hydrology system in response to meltwater forcing. Modelling the integrated hydrological-ice dynamics system to reproduce measured velocities at the ice margin remains a key challenge for validating the present understanding of the system and constraining the impact of increasing surface runoff rates on dynamic ice mass loss from the GrIS. Here we show that a multi-component model incorporating supraglacial, subglacial, and ice dynamic components applied to a land-terminating catchment in western Greenland produces modelled velocities which are in reasonable agreement with those observed in GPS records for three melt seasons of varying melt intensities. This provides numerical support for the hypothesis that the subglacial system develops analogously to alpine glaciers and supports recent model formulations capturing the transition between distributed and channelized states. The model shows the growth of efficient conduit-based drainage up-glacier from the ice sheet margin, which develops more extensively, and further inland, as melt intensity increases. This suggests current trends of decadal-timescale slowdown of ice velocities in the ablation zone may continue in the near future. The model results also show a strong scaling between average summer velocities and melt season intensity, particularly in the upper ablation area. Assuming winter velocities are not impacted by channelization, our model suggests an upper bound of a 25 % increase in annual surface velocities as surface melt increases to 4 × present levels.

Single-Step Seeded-Growth of Graphene Nanoribbons (GNRs) via Plasma-Enhanced Chemical Vapor Deposition (PECVD)

NASA Astrophysics Data System (ADS)

Hsu, C.-C.; Yang, K.; Tseng, W.-S.; Li, Yiliang; Li, Yilun; Tour, J. M.; Yeh, N.-C.

One of the main challenges in the fabrication of GNRs is achieving large-scale low-cost production with high quality. Current techniques, including lithography and unzipped carbon nanotubes, are not suitable for mass production. We have recently developed a single-step PECVD growth process of high-quality graphene sheets without any active heating. By adding some substituted aromatic as seeding molecules, we are able to rapidly grow GNRs vertically on various transition-metal substrates. The morphology and electrical properties of the GNRs are dependent on the growth parameters such as the growth time, gas flow and species of the seeding molecules. On the other hand, all GNRs exhibit strong infrared and optical absorption. From studies of the Raman spectra, scanning electron microscopic images, and x-ray/ultraviolet photoelectron spectra of these GNRs as functions of the growth parameters, we propose a model for the growth mechanism. Our findings suggest that our approach opens up a pathway to large-scale, inexpensive production of GNRs for applications to supercapacitors and solar cells. This work was supported by the Grubstake Award and NSF through IQIM at Caltech.

Rotator cuff repair using cell sheets derived from human rotator cuff in a rat model.

PubMed

Harada, Yoshifumi; Mifune, Yutaka; Inui, Atsuyuki; Sakata, Ryosuke; Muto, Tomoyuki; Takase, Fumiaki; Ueda, Yasuhiro; Kataoka, Takeshi; Kokubu, Takeshi; Kuroda, Ryosuke; Kurosaka, Masahiro

2017-02-01

To achieve biological regeneration of tendon-bone junctions, cell sheets of human rotator-cuff derived cells were used in a rat rotator cuff injury model. Human rotator-cuff derived cells were isolated, and cell sheets were made using temperature-responsive culture plates. Infraspinatus tendons in immunodeficient rats were resected bilaterally at the enthesis. In right shoulders, infraspinatus tendons were repaired by the transosseous method and covered with the cell sheet (sheet group), whereas the left infraspinatus tendons were repaired in the same way without the cell sheet (control group). Histological examinations (safranin-O and fast green staining, isolectin B4, type II collagen, and human-specific CD31) and mRNA expression (vascular endothelial growth factor; VEGF, type II collagen; Col2, and tenomodulin; TeM) were analyzed 4 weeks after surgery. Biomechanical tests were performed at 8 weeks. In the sheet group, proteoglycan at the enthesis with more type II collagen and isolectin B4 positive cells were seen compared with in the control group. Human specific CD31-positive cells were detected only in the sheet group. VEGF and Col2 gene expressions were higher and TeM gene expression was lower in the sheet group than in the control group. In mechanical testing, the sheet group showed a significantly higher ultimate failure load than the control group at 8 weeks. Our results indicated that the rotator-cuff derived cell sheet could promote cartilage regeneration and angiogenesis at the enthesis, with superior mechanical strength compared with the control. Treatment for rotator cuff injury using cell sheets could be a promising strategy for enthesis of tendon tissue engineering. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:289-296, 2017. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

Cell infiltration and growth in a low density, uncompressed three-dimensional electrospun nanofibrous scaffold.

PubMed

Blakeney, Bryan A; Tambralli, Ajay; Anderson, Joel M; Andukuri, Adinarayana; Lim, Dong-Jin; Dean, Derrick R; Jun, Ho-Wook

2011-02-01

A limiting factor of traditional electrospinning is that the electrospun scaffolds consist entirely of tightly packed nanofiber layers that only provide a superficial porous structure due to the sheet-like assembly process. This unavoidable characteristic hinders cell infiltration and growth throughout the nanofibrous scaffolds. Numerous strategies have been tried to overcome this challenge, including the incorporation of nanoparticles, using larger microfibers, or removing embedded salt or water-soluble fibers to increase porosity. However, these methods still produce sheet-like nanofibrous scaffolds, failing to create a porous three-dimensional scaffold with good structural integrity. Thus, we have developed a three-dimensional cotton ball-like electrospun scaffold that consists of an accumulation of nanofibers in a low density and uncompressed manner. Instead of a traditional flat-plate collector, a grounded spherical dish and an array of needle-like probes were used to create a Focused, Low density, Uncompressed nanoFiber (FLUF) mesh scaffold. Scanning electron microscopy showed that the cotton ball-like scaffold consisted of electrospun nanofibers with a similar diameter but larger pores and less-dense structure compared to the traditional electrospun scaffolds. In addition, laser confocal microscopy demonstrated an open porosity and loosely packed structure throughout the depth of the cotton ball-like scaffold, contrasting the superficially porous and tightly packed structure of the traditional electrospun scaffold. Cells seeded on the cotton ball-like scaffold infiltrated into the scaffold after 7 days of growth, compared to no penetrating growth for the traditional electrospun scaffold. Quantitative analysis showed approximately a 40% higher growth rate for cells on the cotton ball-like scaffold over a 7 day period, possibly due to the increased space for in-growth within the three-dimensional scaffolds. Overall, this method assembles a nanofibrous scaffold that is more advantageous for highly porous interconnectivity and demonstrates great potential for tackling current challenges of electrospun scaffolds. 2010 Elsevier Ltd. All rights reserved.

Penetration of the Interplanetary Magnetic Field B(sub y) into Earth's Plasma Sheet

NASA Technical Reports Server (NTRS)

Hau, L.-N.; Erickson, G. M.

1995-01-01

There has been considerable recent interest in the relationship between the cross-tail magnetic field component B(sub y) and tail dynamics. The purpose of this paper is to give an overall description of the penetration of the interplanetary magnetic field (IMF) B(sub y) into the near-Earth plasma sheet. We show that plasma sheet B(sub y) may be generated by the differential shear motion of field lines and enhanced by flux tube compression. The latter mechanism leads to a B(sub y) analogue of the pressure-balance inconsistency as flux tubes move from the far tail toward the Earth. The growth of B(sub y), however, may be limited by the dawn-dusk asymmetry in the shear velocity as a result of plasma sheet tilting. B(sub y) penetration into the plasma sheet implies field-aligned currents flowing between hemispheres. These currents together with the IMF B(sub y) related mantle field-aligned currents effectively shield the lobe from the IMF B(sub y).

Utilization of the terrestrial cyanobacterial sheet

NASA Astrophysics Data System (ADS)

Katoh, Hiroshi; Tomita-Yokotani, Kaori; Furukawa, Jun; Kimura, Shunta; Yamaguchi, Yuji; Takenaka, Hiroyuki; Kohno, Nobuyuki

2016-07-01

The terrestrial nitrogen-fixing cyanobacterium, Nostoc commune, is living ranging from polar to desert. N. commune makes visible colonies composed extracellular polymeric substances. N. commune has expected to utilize for agriculture, food and terraforming cause of its extracellular polysaccharide, desiccation tolerance and nitrogen fixation. To exhibit the potential abilities, the N. commune sheet is made to use convenient and evaluated by plant growth and radioactive accumulation. We will discuss utilization of terrestrial cyanobacteria under closed environment.

Apparatus for melt growth of crystalline semiconductor sheets

DOEpatents

Ciszek, Theodore F.; Hurd, Jeffery L.

1986-01-01

An economical method is presented for forming thin sheets of crystalline silicon suitable for use in a photovoltaic conversion cell by solidification from the liquid phase. Two spatially separated, generally coplanar filaments wettable by liquid silicon and joined together at the end by a bridge member are immersed in a silicon melt and then slowly withdrawn from the melt so that a silicon crystal is grown between the edge of the bridge and the filaments.

The relative value of growth.

PubMed

Mass, Nathaniel J

2005-04-01

Most executives would say that adding a point of growth and gaining a point of operating-profit margin contribute about equally to shareholder value. Margin improvements hit the bottom line immediately, while growth compounds value over time. But the reality is that the two are rarely equivalent. Growth often is far more valuable than managers think. For some companies, convincing the market that they can grow by just one additional percentage point can be worth six, seven, or even ten points of margin improvement. This article presents a new strategic metric, called the relative value of growth (RVG), which gives managers a clear picture of how growth projects and margin improvement initiatives affect shareholder value. Using basic balance sheet and income sheet data, managers can determine their companies' RVGs, as well as those of their competitors. Calculating RVGs gives managers insights into which corporate strategies are working to deliver value and whether their companies are pulling the most powerful value-creation levers. The author examines a number of well-known companies and explains what their RVG numbers say about their strategies. He reviews the unspoken assumption that growth and profits are incompatible over the long term and shows that a fair number of companies are effective at delivering both. Finally, he explains how managers can use the RVG framework to help them define strategies that balance growth and profitability at both the corporate and business unit levels.

General theory of the plasmoid instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Comisso, L.; Lingam, M.; Huang, Y. -M.

2016-10-05

In a general theory of the onset and development of the plasmoid instability is formulated by means of a principle of least time. We derive and show the scaling relations for the final aspect ratio, transition time to rapid onset, growth rate, and number of plasmoids that depend on the initial perturbation amplitude (more » $$\\hat{w}$$ 0), the characteristic rate of current sheet evolution (1/τ), and the Lundquist number (S). They are not simple power laws, and are proportional to S ατ β[ln f(S,τ,$$\\hat{w}$$ 0)] σ. Finally, the detailed dynamics of the instability is also elucidated, and shown to comprise of a period of quiescence followed by sudden growth over a short time scale.« less

Large Area Silicon Sheet by EFG

NASA Technical Reports Server (NTRS)

Wald, F. V.

1979-01-01

Displaced die concepts were explored along with some initial work on buckle characterization. Convective impurity redistribution was further studied. Growth from single cartridges was continued to create a quality baseline to allow comparison of the results with those in the upcoming multiple run and to choose the most appropriate die design. Fabrication and assembly work on the actual five ribbon furnace continued. Progress was made toward the development of the video optical system for edge position and meniscus height control. In preparation for a detailed program, designed to explore the buckling problem, ribbon guidance in the machine was improved. Buckle free, full width ribbon was grown under stable conditions without a cold shoe, an achievement essential to finally arrive at quantitative correlations between growth conditions and buckle formation.

Financial management and dental school strength, Part I: Strategy.

PubMed

Chambers, David W; Bergstrom, Roy

2004-04-01

The ultimate goal of financial management in a dental school is to accumulate assets that are available for strategic growth, which is a parallel objective to the profit motive in business. Budget development is often grounded in an income statement framework where the goal is to match revenues and expenses. Only when a balance sheet perspective (assets = liabilities + equity) is adopted can strategic growth be fully addressed. Four views of budgeting are presented in this article: 1) covering expenses, 2) shopping, 3) strategic support, and 4) budgeting as strategy. These perceptions of the budgeting process form a continuum, moving from a weak strategic position (covering expenses) to a strong one (budgeting as strategy) that encourages the accumulation of assets that build equity in the organization.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, B.; Valdes, P.J.

The U.K. University Global Atmospheric Modeling Programme GCM is used to investigate whether the growth of Northern Hemisphere ice sheets could have been initiated by changes of orbital parameters and sea surface temperatures. Two different orbital configurations, corresponding to the present day and 115 kyr BP are used. The reduced summer solar insolation in the Northern Hemisphere results in a decrease of the surface temperature by 4{degrees} to 10{degrees}C in the northern continents and to perennial snow in some high-latitude regions. Therefore, the model results support the hypothesis that a deficit of summer insolation can create conditions favorable for initiationmore » of ice sheet growth in the Northern Hemisphere. A decreased sea surface temperature northward of 65{degrees}N during the Northern Hemisphere summer may contribute to the maintenance of ice sheets. A simple mixed-layer ocean model coupled to the GCM indicates that the changes of sea surface temperature and extension of sea ice due to insolation changes play an important role in inception of the Fennoscandian, Laurentide, and Cordilleran ice sheets. The model results suggest that the regions of greatest sensitivity for ice initiation are the Canadian Archipelago, Baffin Island, Tibetan Plateau, Scandinavia, Siberia, Alaska, and Keewatin, where changing orbital parameters to 115 kyr BP results in the snow cover remaining throughout the warmer summer, leading to long-term snow accumulation. The model results are in general agreement with geological evidence and are the first time that a GCM coupled with a mixed layer ocean has reproduced the inception of the Northern Hemisphere ice sheets. 69 refs., 21 figs., 3 tabs.« less

Nonlinear Dynamics of Non-uniform Current-Vortex Sheets in Magnetohydrodynamic Flows

NASA Astrophysics Data System (ADS)

Matsuoka, C.; Nishihara, K.; Sano, T.

2017-04-01

A theoretical model is proposed to describe fully nonlinear dynamics of interfaces in two-dimensional MHD flows based on an idea of non-uniform current-vortex sheet. Application of vortex sheet model to MHD flows has a crucial difficulty because of non-conservative nature of magnetic tension. However, it is shown that when a magnetic field is initially parallel to an interface, the concept of vortex sheet can be extended to MHD flows (current-vortex sheet). Two-dimensional MHD flows are then described only by a one-dimensional Lagrange parameter on the sheet. It is also shown that bulk magnetic field and velocity can be calculated from their values on the sheet. The model is tested by MHD Richtmyer-Meshkov instability with sinusoidal vortex sheet strength. Two-dimensional ideal MHD simulations show that the nonlinear dynamics of a shocked interface with density stratification agrees fairly well with that for its corresponding potential flow. Numerical solutions of the model reproduce properly the results of the ideal MHD simulations, such as the roll-up of spike, exponential growth of magnetic field, and its saturation and oscillation. Nonlinear evolution of the interface is found to be determined by the Alfvén and Atwood numbers. Some of their dependence on the sheet dynamics and magnetic field amplification are discussed. It is shown by the model that the magnetic field amplification occurs locally associated with the nonlinear dynamics of the current-vortex sheet. We expect that our model can be applicable to a wide variety of MHD shear flows.

Stress studies in EFG

NASA Technical Reports Server (NTRS)

1983-01-01

Experimental work in support of stress studies in high speed silicon sheet growth has been emphasized in this quarter. Creep experiments utilizing four-point bending have been made in the temperature range from 1000 C to 1360 C in CZ silicon as well as on EFG ribbon. A method to measure residual stress over large areas using laser interferometry to map strain distributions under load is under development. A fiber optics sensor to measure ribbon temperature profiles has been constructed and is being tested in a ribbon growth furnace environment. Stress and temperature field modeling work has been directed toward improving various aspects of the finite element computing schemes. Difficulties in computing stress distributions with a very high creep intensity and with non-zero interface stress have been encountered and additional development of the numerical schemes to cope with these problems is required. Temperature field modeling has been extended to include the study of heat transfer effects in the die and meniscus regions.

Predictive Capabilities of Multiphysics and Multiscale Models in Modeling Solidification of Steel Ingots and DC Casting of Aluminum

NASA Astrophysics Data System (ADS)

Combeau, Hervé; Založnik, Miha; Bedel, Marie

2016-08-01

Prediction of solidification defects, such as macrosegregation and inhomogeneous microstructures, constitutes a key issue for industry. The development of models of casting processes needs to account for several imbricated length scales and different physical phenomena. For example, the kinetics of the growth of microstructures needs to be coupled with the multiphase flow at the process scale. We introduce such a state-of-the-art model and outline its principles. We present the most recent applications of the model to casting of a heavy steel ingot and to direct chill casting of a large Al alloy sheet ingot. Their ability to help in the understanding of complex phenomena, such as the competition between nucleation and growth of grains in the presence of convection of the liquid and of grain motion is shown, and its predictive capabilities are discussed. Key issues for future developments and research are addressed.

Non-normal perturbation growth in idealised island and headland wakes

NASA Astrophysics Data System (ADS)

Aiken, C. M.; Moore, A. M.; Middleton, J. H.

2003-12-01

Generalised linear stability theory is used to calculate the linear perturbations that furnish most rapid growth in energy in a model of a steady recirculating island wake. This optimal peturbation is found to be antisymmetric and to evolve into a von Kármán vortex street. Eigenanalysis of the linearised system reveals that the eigenmodes corresponding to vortex sheet formation are damped, so the growth of the perturbation is understood through the non-normality of the linearised system. Qualitatively similar perturbation growth is shown to occur in a non-linear model of stochastically-forced subcritical flow, resulting in transition to an unsteady wake. Free-stream variability with amplitude 8% of the mean inflow speed sustains vortex street structures in the non-linear model with perturbation velocities the order of the inflow speed, suggesting that environmental stochastic forcing may similarly be capable of exciting growing disturbances in real island wakes. To support this, qualitatively similar perturbation growth is demonstrated in the straining wake of a realistic island obstacle. It is shown that for the case of an idealised headland, where the vortex street eigenmodes are lacking, vortex sheets are produced through a similar non-normal process.

Wafer-Scale and Wrinkle-Free Epitaxial Growth of Single-Orientated Multilayer Hexagonal Boron Nitride on Sapphire.

PubMed

Jang, A-Rang; Hong, Seokmo; Hyun, Chohee; Yoon, Seong In; Kim, Gwangwoo; Jeong, Hu Young; Shin, Tae Joo; Park, Sung O; Wong, Kester; Kwak, Sang Kyu; Park, Noejung; Yu, Kwangnam; Choi, Eunjip; Mishchenko, Artem; Withers, Freddie; Novoselov, Kostya S; Lim, Hyunseob; Shin, Hyeon Suk

2016-05-11

Large-scale growth of high-quality hexagonal boron nitride has been a challenge in two-dimensional-material-based electronics. Herein, we present wafer-scale and wrinkle-free epitaxial growth of multilayer hexagonal boron nitride on a sapphire substrate by using high-temperature and low-pressure chemical vapor deposition. Microscopic and spectroscopic investigations and theoretical calculations reveal that synthesized hexagonal boron nitride has a single rotational orientation with AA' stacking order. A facile method for transferring hexagonal boron nitride onto other target substrates was developed, which provides the opportunity for using hexagonal boron nitride as a substrate in practical electronic circuits. A graphene field effect transistor fabricated on our hexagonal boron nitride sheets shows clear quantum oscillation and highly improved carrier mobility because the ultraflatness of the hexagonal boron nitride surface can reduce the substrate-induced degradation of the carrier mobility of two-dimensional materials.

Crack growth through the thickness of thin-sheet Hydrided Zircaloy-4

NASA Astrophysics Data System (ADS)

Raynaud, Patrick A. C.

In recent years, the limits on fuel burnup have been increased to allow an increase in the amount of energy produced by a nuclear fuel assembly thus reducing waste volume and allowing greater capacity factors. As a result, it is paramount to ensure safety after longer reactor exposure times in the case of design-basis accidents, such as reactivity-initiated accidents (RIA). Previously proposed failure criteria do not directly address the particular cladding failure mechanism during a RIA, in which crack initiation in brittle outer-layers is immediately followed by crack growth through the thickness of the thin-wall tubing. In such a case, the fracture toughness of hydrided thin-wall cladding material must be known for the conditions of through-thickness crack growth in order to predict the failure of high-burnup cladding. The fracture toughness of hydrided Zircaloy-4 in the form of thin-sheet has been examined for the condition of through-thickness crack growth as a function of hydride content and distribution at 25°C, 300°C, and 375°C. To achieve this goal, an experimental procedure was developed in which a linear hydride blister formed across the width of a four-point bend specimen was used to inject a sharp crack that was subsequently extended by fatigue pre-cracking. The electrical potential drop method was used to monitor the crack length during fracture toughness testing, thus allowing for correlation of the load-displacement record with the crack length. Elastic-plastic fracture mechanics were used to interpret the experimental test results in terms of fracture toughness, and J-R crack growth resistance curves were generated. Finite element modeling was performed to adapt the classic theories of fracture mechanics applicable to thick-plate specimens to the case of through-thickness crack growth in thin-sheet materials, and to account for non-uniform crack fronts. Finally, the hydride microstructure was characterized in the vicinity of the crack tip by means of digital image processing, so as to understand the influence of the hydride microstructure on fracture toughness, at the various test temperatures. Crack growth occurred through a microstructure which varied within the thickness of the thin-sheet Zircaloy-4 such that the hydrogen concentration and the radial hydride content decreased with increasing distance from the hydride blister. At 25°C, the fracture toughness was sensitive to the changes in hydride microstructure, such that the toughness KJi decreased from 39 MPa√m to 24 MPa√m with increasing hydrogen content and increasing the fraction of radial hydrides. The hydride particles present in the Zircaloy-4 substrate fractured ahead of the crack tip, and crack growth occurred by linking the crack-tip with the next hydride-induced primary void ahead of it. Unstable crack growth was observed at 25°C prior to any stable crack growth in the specimens where the hydrogen content was the highest. At 375°C as well as in most cases at 300°C, the hydride particles were resistant to cracking and the resistance to crack-growth initiation was very high. As a result, for this bend test procedure, crack extension was solely due to crack-tip blunting instead of crack growth in all tests at 375°C and in most cases at 300°C. The lower bound for fracture toughness at these temperatures, the parameter KJPmax, had values of K JPmax˜54MPa√m at both 300°C and 375°C. For cases where stable crack growth occurred at 300°C, the fracture toughness was K Ji˜58MPa√m and the tearing modulus was twice as high as that at 25°C. It is believed that the failure of hydrided Zircaloy-4 thin-wall cladding can be predicted using fracture mechanics analyses when failure occurs by crack growth. This failure mechanism was observed to occur in all cases at 25°C and in some cases at 300°C. However, at more elevated temperatures, such as 375°C, failure will likely occur by a mechanism other than crack growth, possibly by an imperfection-induced shear instability.

A cross-field current instability for substorm expansions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lui, A.T.Y.; Chang, C.L.; Mankofsky, A.

1991-07-01

The authors investigate a cross-field current instability (CFCI) as a candidate for current disruption during substorm expansions. The numerical solution of the linear dispersion equation indicates that (1) the proposed instability can occur at the inner edge or the midsection of the neutral sheet just prior to the substorm expansion onset although the former environment is found more favorable at the same drift speed scaled to the ion thermal speed, (2) the computed growth time is comparable to the substorm onset time, and (3) the excited waves have a mixed polarization with frequencies near the ion gyrofrequency at the innermore » edge and near the lower hybrid frequency in the midtail region. On the basis of this analysis, they propose a substorm development scenario in which plasma sheet thinning during the substorm growth phase leads to an enhancement in the relative drift between ions and electrons. This results in the neutral sheet being susceptible to the CHCI and initiates the diversion of the cross-tail current through the ionosphere. Whether or not a substorm current wedge is ultimately formed is regulated by the ionospheric condition. A large number of substorm features can be readily understood with the proposed scheme. These include (1) precursory activities (pseudobreakups) prior to substorm onset, (2) substorm initiation region to be spatially localized, (3) three different solar wind conditions for substorm occurence, (4) skew towards evening local times for substorm onset locations, (5) different acceleration characteristics between ions and electrons, (6) tailward spreading of current disruption region after substorm onset, and (7) local time expansion of substorm current wedge with possible discrete westward jump for the evening expansion.« less

Enhanced intestinal anastomotic healing with gelatin hydrogel incorporating basic fibroblast growth factor.

PubMed

Hirai, Kenjiro; Tabata, Yasuhiko; Hasegawa, Suguru; Sakai, Yoshiharu

2016-10-01

Anastomotic leakage is a common complication of intestinal surgery. In an attempt to resolve this issue, a promising approach is enhancement of anastomotic wound healing. A method for controlled release of basic fibroblast growth factor (bFGF) using a gelatin hydrogel was developed with the objective of investigating the effects of this technology on intestinal anastomotic healing. The small intestine of Wistar rats was cut, end-to-end anastomosis was performed and rats were divided into three groups: bFGF group (anastomosis wrapped with a hydrogel sheet incorporating bFGF), PBS group (wrapped with a sheet incorporating phosphate-buffered saline solution) and NT group (no additional treatment). Degradation profiles of gelatin hydrogels in vivo and histological examinations were performed using gelatin hydrogels with various water contents and bFGF concentrations to define the optimal bFGF dose and hydrogel biodegradability. The anastomotic wound healing process was evaluated by histological examinations, adhesion-related score and bursting pressure. The optimal water content of the hydrogel and bFGF dose was determined as 96% and 30 µg per sheet, respectively. Application of bFGF significantly enhanced neovascularization, fibroblast infiltration and collagen production around the anastomotic site when compared with the other groups. Bursting pressure was significantly increased in the bFGF group. No significant difference was observed in the adhesion-related score among the groups and no anastomotic obstruction and leakage were observed. Therefore controlled release of bFGF enhanced healing of an intestinal anastomosis during the early postoperative period and is a promising method to suppress anastomotic leakage. Copyright © 2013 John Wiley & Sons, Ltd. Copyright © 2013 John Wiley & Sons, Ltd.

Ultra-thin grain-oriented silicon steel sheet fabricated by a novel way: Twin-roll strip casting and two-stage cold rolling

NASA Astrophysics Data System (ADS)

Wang, Yin-Ping; Liu, Hai-Tao; Song, Hong-Yu; Liu, Jia-Xin; Shen, Hui-Ying; Jin, Yang; Wang, Guo-Dong

2018-04-01

0.05-0.15 mm-thick ultra-thin grain-oriented silicon steel sheets were successfully produced by a novel processing route including strip casting, hot rolling, normalizing, two-stage cold rolling with intermediate annealing, primary recrystallization annealing and secondary recrystallization annealing. The evolutions of microstructure, texture and inhibitor along the processing were briefly investigated. The results showed that the initial Goss orientation originated due to the heterogenous nucleation of δ-ferrite grains during solidification. Because of the lack of shear deformation, only a few Goss grains were observed in the hot rolled sheet. After the first cold rolling and intermediate annealing, Goss texture was enhanced and distributed in the whole thickness. A small number of Goss grains having a high fraction of high energy boundaries exhibited in the primary recrystallization annealed sheet. A large number of fine and dispersed MnS and AlN and a few co-precipitates MnS and AlN with the size range of 10-70 nm were also observed. Interestingly, a well-developed secondary recrystallization microstructure characterized by 10-60 mm grains and a sharp Goss texture were finally produced in the 0.05-0.15 mm-thick ultra-thin sheets. A magnetic induction B8 of 1.72-1.84 T was obtained. Another new finding was that a few {2 3 0}〈0 0 1〉 and {2 1 0}〈1 2 7〉 grains also can grow up abnormally because of the high fraction of high energy boundaries and the size and number advantage, respectively. These non-Goss grains finally deteriorated the magnetic properties of the ultra-thin sheets. In addition, low surface energies of {hk0} planes may also contribute to the abnormal growth of Goss, {2 3 0}〈0 0 1〉 and {2 1 0}〈1 2 7〉 grains.

Promoting Sustainable Economic Growth in Mexico (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, A.; Butheau, M.; Sandor, D.

2013-11-01

Mexico is the second largest economy in Latin America, with rapid growth occurring in the industrial and services sectors. A forward-thinking country on climate change, the nation recognizes that the threat of higher temperatures, changes in precipitation patterns, and more frequent weather-related disasters could pose a substantial risk to its expanding economy.

Growth of Greenland ice sheet - Interpretation

NASA Technical Reports Server (NTRS)

Zwally, H. Jay

1989-01-01

An observed 0.23 m/year thickening of the Greenland ice sheet indicates a 25 percent to 45 percent excess ice accumulation over the amount required to balance the outward ice flow. The implied global sea-level depletion is 0.2 to 0.4 mm/year, depending on whether the thickening is only recent (5 to 10 years) or longer term (less than 100 years). If there is a similar imbalance in the northern 60 percent of the ice-sheet area, the depletion is 0.35 to 0.7 mm/year. Increasing ice thickness suggests that the precipitation is higher than the long-term average; higher precipitation may be a characteristic of warmer climates in polar regions.

The growth and differentiation of transitional epithelium in vitro.

PubMed

Chlapowski, F J; Haynes, L

1979-12-01

The development of rat transitional epithelial cells grown on conventional non-permeable surfaces was compared with development on permeable collagen supports. On glass or plastic surfaces, cells grew as expanding nomolayer sheets. Once confluent, growth continued with a bilayer being formed in most areas and apical cells being continuously sloughed off. Although most cells were interconnected by desmosomes, and junctional complexes were formed, no other indications of differentiation were observed. After 2-3 wk of growth, division stopped and cel death ensued. In contrast, single-cell suspensions plated on collagen-coated nylon disks reassociated into multicellular islands and commenced growth. Mitoses were confined to the basal cells in contact with the permeable substrate. The islands developed into epithelial trilayers, tapering to monolayers along spreading edges. Once the islands were confluent, stratification was completed and appeared similar to that observed in vivo. Germinal cells formed a basal lamina, and the upper layer was composed of large, flattened cells with an unusually thick asymmetrical plasma membrane on the apical surface. Electron microscopic and radioactive tracers demonstrated "leaky" zonulae occludentes with a restricted permeability to small molecules. The movement of urea was retarded in comparison to water. Unlike the slow turnover of adult epithelium in vivo, maturation and sloughing of apical cells were measurable. Transfer of cells could be effected and growth maintained for up to 4 mo. These results may indicate the necessity of a nutrient-permeable growth surface for the polarized differentiation of adult transitional epithelium.

The growth and differentiation of transitional epithelium in vitro

PubMed Central

1979-01-01

The development of rat transitional epithelial cells grown on conventional non-permeable surfaces was compared with development on permeable collagen supports. On glass or plastic surfaces, cells grew as expanding nomolayer sheets. Once confluent, growth continued with a bilayer being formed in most areas and apical cells being continuously sloughed off. Although most cells were interconnected by desmosomes, and junctional complexes were formed, no other indications of differentiation were observed. After 2-3 wk of growth, division stopped and cel death ensued. In contrast, single-cell suspensions plated on collagen-coated nylon disks reassociated into multicellular islands and commenced growth. Mitoses were confined to the basal cells in contact with the permeable substrate. The islands developed into epithelial trilayers, tapering to monolayers along spreading edges. Once the islands were confluent, stratification was completed and appeared similar to that observed in vivo. Germinal cells formed a basal lamina, and the upper layer was composed of large, flattened cells with an unusually thick asymmetrical plasma membrane on the apical surface. Electron microscopic and radioactive tracers demonstrated "leaky" zonulae occludentes with a restricted permeability to small molecules. The movement of urea was retarded in comparison to water. Unlike the slow turnover of adult epithelium in vivo, maturation and sloughing of apical cells were measurable. Transfer of cells could be effected and growth maintained for up to 4 mo. These results may indicate the necessity of a nutrient-permeable growth surface for the polarized differentiation of adult transitional epithelium. PMID:574872

Effect of Sn Micro-alloying on Recrystallization Nucleation and Growth Processes of Ferritic Stainless Steels

NASA Astrophysics Data System (ADS)

He, Tong; Bai, Yang; Liu, Xiuting; Guo, Dan; Liu, Yandong

2018-04-01

We investigated the effect of Sn micro-alloying on recrystallization nucleation and growth processes of ferritic stainless steels. The as-received hot rolled sheets were cold rolled up to 80% reduction and then annealed at 740-880 °C for 5 min. The cold rolling and recrystallization microstructures and micro-textures of Sn-containing and Sn-free ferritic stainless steels were all determined by electron backscatter diffraction. Our Results show that Sn micro-alloying has important effects on recrystallization nucleation and growth processes of ferritic stainless steels. Sn micro-alloying conduces to grain fragmentation in the deformation band, more fragmented grains are existed in Sn-containing cold rolled sheets, which provides more sites for recrystallization nucleation. Sn micro-alloying also promotes recrystallization process and inhibits the growth of recrystallized grains. The recrystallization nucleation and growth mechanism of Sn-containing and Sn-free ferritic stainless steels are both characterized by orientation nucleation and selective growth, but Sn micro-alloying promotes the formation of γ-oriented grains. Furthermore, Sn micro-alloying contributes to the formation of Σ13b CSL boundaries and homogeneous γ-fiber texture. Combining the results of microstructure and micro-texture, the formability of Sn-containing ferritic stainless steels will be improved to some extent.

Distribution of garnet grain sizes and morphologies across the Moine Supergroup, northern Scottish Caledonides

NASA Astrophysics Data System (ADS)

Ashley, Kyle T.; Thigpen, J. Ryan; Law, Richard D.

2016-04-01

Garnet is used in a wide range of geologic studies due to its important physical and chemical characteristics. While the mineral is useful for thermobarometry and geochronology constraints and can often be correlated to deformation and fabric development, difficulties remain in making meaningful interpretations of such data. In this study, we characterize garnet grain sizes and crystal morphologies from 141 garnet-bearing metasedimentary rock samples collected from the northern part of the Moine Supergroup in the Scottish Caledonides. Larger, euhedral crystals are indicative of prograde metamorphic growth and are typically associated with the most recent phase of orogenesis (Scandian, ˜430 Ma). Small, rounded ("pin-head") garnets are interpreted as detrital in origin. A subhedral classification is more subjective and is used when garnets contains portions of straight boundaries but have rounded edges or rims that have been altered through retrograde metamorphic reactions. From our collection, 88 samples contain anhedral garnets (maximum measured grain size d = 0.46 ± 0.21 mm), 34 bear subhedral garnets (d = 2.0 ± 1.0 mm), and the remaining 19 samples contain garnets with euhedral grains (d = 4.4 ± 2.6 mm). Plotting the distribution of garnets relative to the mapped thrust contacts reveals an abrupt change in morphology and grain size when traced from the Moine thrust sheet across the Ben Hope and Sgurr Beag thrusts into the higher-grade, more hinterland-positioned thrust sheets. The dominance of anhedral garnets in the Moine thrust sheet suggests that these grains should not be used for peak P - T estimation associated with relatively low temperature (<500 ° C) Scandian metamorphism, as they are likely detrital in origin and contain protolith chemical signatures that would not have been reset due to sluggish diffusivities at greenschist facies temperatures. However, chemical and isotopic data from these grains may provide information into the provenance of these metasediments. A thermal/chemical break must occur at the Ben Hope thrust, because hanging wall garnets contain euhedral (Scandian?) rims that are distinct from the garnet grains observed in the underlying Moine thrust sheet. In addition to morphology, the propensity of garnet to include minerals during growth makes it a useful phase for obtaining a historical perspective on growth conditions. The distribution and chemistries of minerals included/encapsulated by garnet was studied for various samples to gain insight into metamorphic evolution and to distinguish garnets that likely contain multiple generations of growth. Although our results are specific to the Caledonides of northern Scotland, this work highlights the general necessity of a comprehensive petrographic assessment of garnet grains in advance of interpreting large suits of garnet-derived thermodynamic and geochronologic data.

Deformation and annealing response of TD-nickel chromium

NASA Technical Reports Server (NTRS)

Kane, R. D.; Ebert, L. J.

1975-01-01

The recrystallization and grain growth processes occurring in TD-NiCr were examined with respect to deformation severity, annealing time, and temperature. Results indicated that two different annealing responses of TD-NiCr are possible, depending on the initial state and processing history prior to annealing. As-received sheet showed a dramatic increase in grain size with decreasing annealing temperature, whereas sheet prior-annealed at 1316 C for 1 hr exhibited very little variation with subsequent annealing temperature.

Method and apparatus for melt growth of crystalline semiconductor sheets

DOEpatents

Ciszek, T.F.; Hurd, J.L.

1981-02-25

An economical method is presented for forming thin sheets of crystalline silicon suitable for use in a photovoltaic conversion cell by solidification from the liquid phase. Two spatially separated, generally coplanar filaments wettable by liquid silicon and joined together at the end by a bridge member are immersed in a silicon melt and then slowly withdrawn from the melt so that a silicon crystal is grown between the edge of the bridge and the filaments.

Effects of Different R ratios on Fatigue Crack Growth in Laser Peened Friction Stir Welds

NASA Technical Reports Server (NTRS)

Hatamleh, Omar; Hackel, Lloyd; Forth, Scott

2007-01-01

The influence of laser peening on the fatigue crack growth behavior of friction stir welded (FSW) Aluminum Alloy (AA) 7075-T7351 sheets was investigated. The surface modification resulting from the peening process on the fatigue crack growth of FSW was assessed for two different R ratios. The investigation indicated a significant decrease in fatigue crack growth rates resulting from using laser shock peening compared with unpeened, welded and unwelded specimens. The slower fatigue crack growth rate was attributed to the compressive residual stresses induced by the peening.

Large area silicon sheet by EFG

NASA Technical Reports Server (NTRS)

1981-01-01

A multiple growth run with three 10 cm cartridges was carried out with the best throughput rates and time percentage of simultaneous three ribbon growth achieved to date in this system. Growth speeds were between 3.2 and 3.6 cm/minute on all three cartridges and simultaneous full width growth of three ribbons was achieved 47 percent of the time over the eight hour duration of the experiment. Improvements in instrumentation and in the main zone temperature uniformity were two factors that have led to more reproducible growth conditions in the multiple ribbon furnace.

Towards a complete conceptual model of substorm onsets and expansions

NASA Technical Reports Server (NTRS)

Erickson, Gary M.; Burke, William J.; Heinemann, Michael; Samson, John C.; Maynard, Nelson C.

1996-01-01

Observational results from the CRRES satellite near times of substorm onsets support the theoretical premise that substorms initiate near the inner edge of the plasma sheet. The region is connected latitudinally to the equatorward-most pre-breakup arc. During the growth phase, the inner edge of the plasma sheet moves towards the earth. This motion is modulated by various cavity oscillations of the magnetosphere-ionosphere coupled magnetosphere. This modulation can locally reverse the background convection electric field. The reversed convection taps energy stored in the inner-edge region of the plasma sheet. The near earth plasma sheet moves out of equilibrium with the lobes, and a rarefaction is launched tailward. This allows current driven dissipation to grow and a near-earth X-line to form. A model is presented which explains the observations of the CRRES satellite, and can account for the behavior associated with auroral intensification and substorm onset.

High export of dissolved silica from the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Meire, L.; Meire, P.; Struyf, E.; Krawczyk, D. W.; Arendt, K. E.; Yde, J. C.; Juul Pedersen, T.; Hopwood, M. J.; Rysgaard, S.; Meysman, F. J. R.

2016-09-01

Silica is an essential element for marine life and plays a key role in the biogeochemistry of the ocean. Glacial activity stimulates rock weathering, generating dissolved silica that is exported to coastal areas along with meltwater. The magnitude of the dissolved silica export from large glacial areas such as the Greenland Ice Sheet is presently poorly quantified and not accounted for in global budgets. Here we present data from two fjord systems adjacent to the Greenland Ice Sheet which reveal a large export of dissolved silica by glacial meltwater relative to other macronutrients. Upscaled to the entire Greenland Ice Sheet, the export of dissolved silica equals 22 ± 10 Gmol Si yr-1. When the silicate-rich meltwater mixes with upwelled deep water, either inside or outside Greenland's fjords, primary production takes place at increased silicate to nitrate ratios. This likely stimulates the growth of diatoms relative to other phytoplankton groups.

Kelvin-Helmholtz instability of a thin liquid sheet: Effect of the gas-boundary layer

NASA Astrophysics Data System (ADS)

Tirumkudulu, Mahesh

2017-11-01

It is well known that when a thin liquid sheet moves with respect to a surrounding gas phase, the liquid sheet is susceptible to the Kelvin-Helmholtz instability. Here, flow in both the liquid and the gas phases are assumed to be inviscid. In this work, we include exactly via a perturbation analysis, the influence of the growing boundary layer in the gas phase in the base flow and show that both temporal and spatial growth rates obtained from the linear stability analysis are significantly reduced due to the presence of the boundary layer. These results are in line with the simulation results of Lozano et al. and Tammisola et al.. We conclude with the implication of these results on the break-up of radially expanding liquid sheets. Funding from IIT Bombay, CSIR India, and Trinity College, Cambridge University is acknowledged.

Project analysis and integration economic analyses summary

NASA Technical Reports Server (NTRS)

Macomber, H. L.

1986-01-01

An economic-analysis summary was presented for the manufacture of crystalline-silicon modules involving silicon ingot/sheet, growth, slicing, cell manufacture, and module assembly. Economic analyses provided: useful quantitative aspects for complex decision-making to the Flat-plate Solar Array (FSA) Project; yardsticks for design and performance to industry; and demonstration of how to evaluate and understand the worth of research and development both to JPL and other government agencies and programs. It was concluded that future research and development funds for photovoltaics must be provided by the Federal Government because the solar industry today does not reap enough profits from its present-day sales of photovoltaic equipment.

A current disruption mechanism in the neutral sheet for triggering substorm expansions

NASA Technical Reports Server (NTRS)

Lui, A. T. Y.; Mankofsky, A.; Chang, C.-L.; Papadopoulos, K.; Wu, C. S.

1989-01-01

Two main areas were addressed in support of an effort to understand mechanism responsible for the broadband electrostatic noise (BEN) observed in the magnetotail. The first area concerns the generation of BEN in the boundary layer region of the magnetotail whereas the second area concerns the occassional presence of BEN in the neutral sheet region. For the generation of BEN in the boundary layer region, a hybrid simulation code was developed to perform reliable longtime, quiet, highly resolved simulations of field aligned electron and ion beam flow. The result of the simulation shows that broadband emissions cannot be generated by beam-plasma instability if realistic values of the ion beam parameters are used. The waves generated from beam-plasma instability are highly discrete and are of high frequencies. For the plasma sheet boundary layer condition, the wave frequencies are in the kHz range, which is incompatible with the observation that the peak power in BEN occur in the 10's of Hz range. It was found that the BEN characteristics are more consistent with lower hybrid drift instability. For the occasional presence of BEN in the neutral sheet region, a linear analysis of the kinetic cross-field streaming instability appropriate to the neutral sheet condition just prior to onset of substorm expansion was performed. By solving numerically the dispersion relation, it was found that the instability has a growth time comparable to the onset time scale of substorm onset. The excited waves have a mixed polarization in the lower hybrid frequency range. The imposed drift driving the instability corresponds to unmagnetized ions undergoing current sheet acceleration in the presence of a cross-tail electric field. The required electric field strength is in the 10 mV/m range which is well within the observed electric field values detected in the neutral sheet during substorms. This finding can potentially account for the disruption of cross-tail current and its diversion to the ionosphere to form the substorm current wedge. Furthermore, a number of features associated with substorm expansion onset can be understood based on this substorm onset scenario.

The shape of a long leaf

PubMed Central

Liang, Haiyi; Mahadevan, L.

2009-01-01

Long leaves in terrestrial plants and their submarine counterparts, algal blades, have a typical, saddle-like midsurface and rippled edges. To understand the origin of these morphologies, we dissect leaves and differentially stretch foam ribbons to show that these shapes arise from a simple cause, the elastic relaxation via bending that follows either differential growth (in leaves) or differential stretching past the yield point (in ribbons). We quantify these different modalities in terms of a mathematical model for the shape of an initially flat elastic sheet with lateral gradients in longitudinal growth. By using a combination of scaling concepts, stability analysis, and numerical simulations, we map out the shape space for these growing ribbons and find that as the relative growth strain is increased, a long flat lamina deforms to a saddle shape and/or develops undulations that may lead to strongly localized ripples as the growth strain is localized to the edge of the leaf. Our theory delineates the geometric and growth control parameters that determine the shape space of finite laminae and thus allows for a comparative study of elongated leaf morphology. PMID:19966215

Thermomechanical processing of HAYNES alloy No. 188 sheet to improve creep strength

NASA Technical Reports Server (NTRS)

Klarstrom, D. L.

1978-01-01

Improvements in the low strain creep strength of HAYNES alloy No. 188 thin gauge sheet by means of thermomechanical processing were developed. Processing methods designed to develop a sheet with strong crystallographic texture after recrystallization and to optimize grain size were principally studied. The effects of thickness-to-grain diameter ratio and prestrain on low strain creep strength were also briefly examined. Results indicate that the most significant improvements were obtained in the sheets having a strong crystallographic texture. The low strain creep strength of the textured sheets was observed to be superior to that of standard production sheets in the 922 K to 1255 K temperature range. Tensile, stress rupture, fabricability, and surface stability properties of the experimental sheets were also measured and compared to property values reported for the baseline production sheets.

Cell Adhesion Minimization by a Novel Mesh Culture Method Mechanically Directs Trophoblast Differentiation and Self-Assembly Organization of Human Pluripotent Stem Cells.

PubMed

Okeyo, Kennedy Omondi; Kurosawa, Osamu; Yamazaki, Satoshi; Oana, Hidehiro; Kotera, Hidetoshi; Nakauchi, Hiromitsu; Washizu, Masao

2015-10-01

Mechanical methods for inducing differentiation and directing lineage specification will be instrumental in the application of pluripotent stem cells. Here, we demonstrate that minimization of cell-substrate adhesion can initiate and direct the differentiation of human pluripotent stem cells (hiPSCs) into cyst-forming trophoblast lineage cells (TLCs) without stimulation with cytokines or small molecules. To precisely control cell-substrate adhesion area, we developed a novel culture method where cells are cultured on microstructured mesh sheets suspended in a culture medium such that cells on mesh are completely out of contact with the culture dish. We used microfabricated mesh sheets that consisted of open meshes (100∼200 μm in pitch) with narrow mesh strands (3-5 μm in width) to provide support for initial cell attachment and growth. We demonstrate that minimization of cell adhesion area achieved by this culture method can trigger a sequence of morphogenetic transformations that begin with individual hiPSCs attached on the mesh strands proliferating to form cell sheets by self-assembly organization and ultimately differentiating after 10-15 days of mesh culture to generate spherical cysts that secreted human chorionic gonadotropin (hCG) hormone and expressed caudal-related homeobox 2 factor (CDX2), a specific marker of trophoblast lineage. Thus, this study demonstrates a simple and direct mechanical approach to induce trophoblast differentiation and generate cysts for application in the study of early human embryogenesis and drug development and screening.

Pyrolytic Carbon Coatings on Aligned Carbon Nanotube Assemblies and Fabrication of Advanced Carbon Nanotube/Carbon Composites

NASA Astrophysics Data System (ADS)

Faraji, Shaghayegh

Chemical vapor deposition (CVD) is a technique used to create a pyrolytic carbon (PyC) matrix around fibrous preforms in carbon/carbon (C/C) composites. Due to difficulties in producing three-dimensional carbon nanotube (CNT) assemblies, use of nanotubes in CVD fabricated CNT/C composites is limited. This dissertation describes efforts to: 1) Study the microstructure of PyC deposited on CNTs in order to understand the effect of microstructure and morphology of carbon coatings on graphitization behavior of CNT/PyC composites. This understanding helped to suggest a new approach for controlled radial growth of CNTs. 2) Evaluate the properties of CNT/PyC structures as a novel form of CNT assemblies with resilient, anisotropic and tunable properties. PyC was deposited on aligned sheets of nanotubes, drawn from spinnable CNT arras, using CVD of acetylene gas. At longer deposition times, the microstructure of PyC changed from laminar turbostratic carbon to a disordered carbon. For samples with short PyC deposition times (up to 30 minutes), deposited carbon layer rearranged during graphitization treatment and resulted in a crystalline structure where the coating and original tube walls could not be easily differentiated. In contrast, in samples with longer carbon deposition durations, carbon layers close to the surface of the coating remained disordered even after graphitization thermal treatment. Understanding the effect of PyC microstructure transition on graphitization behavior of CNT/PyC composites was used to develop a new method for controlled radial growth of CNTs. Carbon coated aligned CNT sheets were graphitized after each short (20 minutes) carbon deposition cycle. This prevented development of disorder carbon during subsequent PyC deposition cycles. Using cyclic-graphitization method, thick PyC coating layers were successfully graphitized into a crystalline structure that could not be differentiated from the original nanotube walls. This resulted into radial growth of CNTs, from 40 to 100 nm. Infiltration of PyC into stacked layered sheets of aligned CNTs produced resilient foam-like materials that exhibited complete recovery from 90% compressive strain. PyC coated the junctions between nanotubes and also increased their surface roughness. These changes were assumed to be responsible for the resiliency of the, once inelastic, assembly of nanotubes. While nanotubes' alignment resulted in anisotropic properties of the foams, variation in PyC infiltration duration was used to tune the foams' properties. Further investigation into properties of these foams showed promising results for their application as pressure/strain sensor and selective liquid absorbers for oil spill clean ups. Finally, CNT foams were used as novel substrates for growth of secondary nanotube assemblies. In order to achieve that, foams were first coated with alumina buffer layers using atomic layer deposition (ALD) method. New nanotubes were further grown inside the foams by CVD of acetylene over iron nano-particles. Super low density and highly porous structure of the foams allowed for diffusion of catalyst along with growth gasses into their bulk, which resulted in growth of secondary nanotubes throughout the thickness of the foams. The thickness of the alumina buffer layer was shown to influence CNT nucleation density and growth uniformity across the thickness of the foams. Compressive mechanical testing of the foams showed an order of magnitude increase in compression strength after secondary CNT growth.

Development of a Cell Sheet Transportation Technique for Regenerative Medicine

PubMed Central

Oie, Yoshinori; Nozaki, Takayuki; Takayanagi, Hiroshi; Hara, Susumu; Hayashi, Ryuhei; Takeda, Shizu; Mori, Keisuke; Moriya, Noboru; Soma, Takeshi; Tsujikawa, Motokazu; Saito, Kazuo

2014-01-01

Purpose: A transportation technique for cell sheets is necessary to standardize regenerative medicine. The aim of this article is to develop and evaluate a new transportation technique for cell sheets. Material and Methods: We developed a transportation container with three basic functions: the maintenance of interior temperature, air pressure, and sterility. The interior temperature and air pressure were monitored by a recorder. Human oral mucosal epithelial cells obtained from two healthy volunteers were cultured on temperature-responsive culture dishes. The epithelial cell sheets were transported via an airplane between the Osaka University and Tohoku University using the developed cell transportation container. Histological and immunohistochemical analyses and flow cytometric analyses for cell viability and cell purity were performed for the cell sheets before and 12 h after transportation to assess the influence of transportation on the cell sheets. Sterility tests and screening for endotoxin and mycoplasma in the cell sheets were performed before and after transportation. Results: During transportation via an airplane, the temperature inside the container was maintained above 32°C, and the changes in air pressure remained within 10 hPa. The cell sheets were well stratified and successfully harvested before and after transportation. The expression patterns of keratin 3/76, p63, and MUC16 were equivalent before and after transportation. However, the expression of ZO-1 in the cell sheet after transportation was slightly weaker than that before transportation. The cell viability was 72.0% before transportation and 77.3% after transportation. The epithelial purity was 94.6% before transportation and 87.9% after transportation. Sterility tests and screening for endotoxin and mycoplasma were negative for all cell sheets. Conclusion: The newly developed transportation technique for air travel is essential technology for regenerative medicine and promotes the standardization and spread of regenerative therapies. PMID:24044382

Development of a cell sheet transportation technique for regenerative medicine.

PubMed

Oie, Yoshinori; Nozaki, Takayuki; Takayanagi, Hiroshi; Hara, Susumu; Hayashi, Ryuhei; Takeda, Shizu; Mori, Keisuke; Moriya, Noboru; Soma, Takeshi; Tsujikawa, Motokazu; Saito, Kazuo; Nishida, Kohji

2014-05-01

A transportation technique for cell sheets is necessary to standardize regenerative medicine. The aim of this article is to develop and evaluate a new transportation technique for cell sheets. We developed a transportation container with three basic functions: the maintenance of interior temperature, air pressure, and sterility. The interior temperature and air pressure were monitored by a recorder. Human oral mucosal epithelial cells obtained from two healthy volunteers were cultured on temperature-responsive culture dishes. The epithelial cell sheets were transported via an airplane between the Osaka University and Tohoku University using the developed cell transportation container. Histological and immunohistochemical analyses and flow cytometric analyses for cell viability and cell purity were performed for the cell sheets before and 12 h after transportation to assess the influence of transportation on the cell sheets. Sterility tests and screening for endotoxin and mycoplasma in the cell sheets were performed before and after transportation. During transportation via an airplane, the temperature inside the container was maintained above 32°C, and the changes in air pressure remained within 10 hPa. The cell sheets were well stratified and successfully harvested before and after transportation. The expression patterns of keratin 3/76, p63, and MUC16 were equivalent before and after transportation. However, the expression of ZO-1 in the cell sheet after transportation was slightly weaker than that before transportation. The cell viability was 72.0% before transportation and 77.3% after transportation. The epithelial purity was 94.6% before transportation and 87.9% after transportation. Sterility tests and screening for endotoxin and mycoplasma were negative for all cell sheets. The newly developed transportation technique for air travel is essential technology for regenerative medicine and promotes the standardization and spread of regenerative therapies.

Chitosan reinforced apatite-wollastonite coating by electrophoretic deposition on titanium implants.

PubMed

Sharma, Smriti; Soni, Vivek P; Bellare, Jayesh R

2009-07-01

A novel bioactive porous apatite-wollastonite/chitosan composite coating was prepared by electrophoretic deposition. The influence of synthesis parameters like pH of suspension and current density was studied and optimized. X-ray diffraction confirmed crystalline phase of apatite-wollastonite in powder as well as composite coating with coat crystallinity of 65%. Scanning electron microscope showed that the porosity had interconnections with good homogeneity between the phases. The addition of chitosan increased the adhesive strength of the composite coating. Young's modulus of the coating was found to be 9.23 GPa. One of our key findings was sheet-like apatite growth unlike ball-like growth found in bioceramics. Role of chitosan was studied in apatite growth mechanism in simulated body fluid. In presence of chitosan, dense negatively charged surface with homogenous nucleation was the primary factor for sheet-like evolution of apatite layer. The results suggest that incorporation of chitosan with apatite-wollastonite in composite coating could provide excellent in vitro bioactivity with enhanced mechanical properties.

Current disruptions in the near-earth neutral sheet region

NASA Technical Reports Server (NTRS)

Lui, A. T. Y.; Lopez, R. E.; Anderson, B. J.; Takahashi, K.; Zanetti, L. J.; Mcentire, R. W.; Potemra, T. A.; Klumpar, D. M.; Greene, E. M.; Strangeway, R.

1992-01-01

Current disruption events observed by the Charge Composition Explorer during 1985 and 1986 are examined. Occurrence of current disruption was accompanied by large magnetic field turbulence and frequently with reversal in the sign of the field component normal to the neutral sheet. Current disruptions in the near-earth region are found to be typically shortlived (about 1-5 min), and their onsets coincide well with the ground onsets of substorm expansion or intensification in the local time sector of the footpoint of the spacecraft. These events are found almost exclusively close to the field reversal plane of the neutral sheet (within about 0.5 RE). Prior to current disruption the field strength can be reduced to as low as one seventh of the dipole field value and can recover to nearly the dipole value after disruption. The temporal evolution of particle pressure in the near-earth neutral sheet during the onset of current disruption indicates that the current buildup during the substorm growth phase is associated with enhancement in the particle pressure at the neutral sheet.

[Developing patient information sheets in general practice. Proposal for a methodology].

PubMed

Sustersic, Mélanie; Meneau, Aurélia; Drémont, Roger; Paris, Adeline; Laborde, Laurent; Bosson, Jean-Luc

2008-12-15

Health information is patients' wish and right. For general practitioners, it is a duty, a legal obligation and a pre-requisite in any preventive approach. Written information must complete oral information since it improves health care quality. However, in general practice, there are no patient documents which are scientifically valid, understandable and efficient in terms of communication. To develop a method for creating patient information sheets and to experiment its feasibility through the development of 125 sheets focused on the most common clinical conditions in general practice. Research and literature review pour the development of specifications, and creation of 125 sheets following these specifications. The specifications developed consist of the 10 following steps: selection of the topic and the objectives, literature review, selection of the sections, drafting, validation of the scientific contents, assessment among patients, validation of the layout, selection of the media, delivery to patients and update. Following these specifications, we developed 125 information sheets. Each of these was reviewed by several physicians and assessed with R. Flesh readability test (the established acceptable threshold value was 40). The 30 sheets associated with the lowest scores were selected and reviewed to improve their overall readability. Even though some difficulties cannot be avoided when developing patient information sheets, each physician or physician association can create its own documents following the proposed specifications and thus deliver a customized message.

Annealing Effects on the Formation of Copper Oxide Thin Films

NASA Astrophysics Data System (ADS)

Marzuki, Marina; Zamzuri Mohamad Zain, Mohd; Zarul Hisham, Nurazhra; Zainon, Nooraizedfiza; Harun, Azmi; Nani Ahmad, Rozie

2018-03-01

This study approached the simple method of developing CuO thin films by thermal oxidation on pure Cu sheets. The effects of annealing temperature on the formation of CuO layers have been investigated. The oxide layers have been fabricated by annealing of Cu sheets for 5 hours at different temperatures of 980 ~ 1010 °C. The morphologies and optical properties of annealed Cu sheets were studied by using SEM and UV-Vis spectrophotometer respectively. It is revealed that the annealing temperature influence the grain growth and the grain size increases as the temperature increase. The highest grain size was observed on sample annealed at 1000 °C with average area per grain size of 0.023 mm2. Theoretically, larger grain size provides less barriers for electron mobility and increase the efficiency of solar devices. The optical absorption spectra of the oxide films was also measured. Interference pattern was noted at wavelength about 900 nm corresponding to the formation of CuO film. The interference noise observed could be due to the coarse surface and the presence of powdery oxide deposits that causes the scattering loses from the surface. CuO film obtained by this method may be further studied and exploited as low cost photovoltaic device.

Using Antifreeze Proteins to understand ice microstructure evolution

NASA Astrophysics Data System (ADS)

Bayer-Giraldi, Maddalena; Azuma, Nobuhiko; Takata, Morimasa; Weikusat, Christian; Kondo, Hidemasa; Kipfstuhl, Sepp

2017-04-01

Polar ice sheets are considered a unique climate archive. The chemical analysis of its impurities and the development of its microstructure with depth give insight in past climate conditions as well as in the development of the ice sheet with time and deformation. Microstructural patterns like small grain size observed in specific depths are thought to be linked to the retarding effect of impurities on ice grain growth. Clear evidence of size or chemical composition of the impurities causing this effect is missing, but in this context a major role of nanoparticles has been suggested. In order to shed light on different mechanisms by which nanoparticles can control microstructure development we used antifreeze proteins (AFPs) as proxies for particles in ice. These proteins are small nanoparticles, approx. 5 nm in size, with the special characteristics of firmly binding to ice through several hydrogen bonds. We used AFPs from the sea-ice microalgae Fragilariopsis cylindrus (fcAFPs) in bubble-free, small-grained polycrystalline ice obtained by the phase-transition size refinement method. We explain how fcAFP bind to ice by presenting the 3-D-protein structure model inferred by X-ray structure analysis, and show the importance of the chemical interaction between particles and ice in controlling normal grain growth, comparing fcAFPs to other protein nanoparticles. We used modifications of fcAFPs for particle localization through fluorescence spectroscopy. Furthermore, the effect of fcAFPs on the driving factors for ice deformation during creep, i.e. on internal dislocations due to incorporation within the lattice and on the mobility of grain boundaries due to pinning, makes these proteins particularly interesting in studying the process of ice deformation.

Assessment of East Antarctic ice flow directions, ice grounding events, and glacial thermal regime across the middle Miocene climate transition from the ANDRILL-SMS and CRP drill holes

NASA Astrophysics Data System (ADS)

Passchier, S.; Hauptvogel, D.; Hansen, M.; Falk, C.; Martin, L.

2010-12-01

Here we present a synthesis of early and middle Miocene ice sheet development based on facies analyses and multiple compositional studies on the AND-2A and CRP drillcores from the Ross Sea, ca. 10 km off the coast of East Antarctica. The middle Miocene is characterized by one of the three largest shifts in deep-sea oxygen isotope records. During this time the East Antarctic ice sheet became dry-based at high elevation in the Transantarctic Mountains and advanced across the Ross Sea continental shelf to create widespread glacial unconformities. However, detailed proxy records also indicate that ice development was complex and may have occurred in a stepwise fashion, instead of one major episode. Our analyses of “grounded ice” diamictites from both the CRP and AND-2A cores show a significant change in composition across the middle Miocene transition. More detailed analyses of the stratigraphic distribution of facies, heavy mineral provenance, particle size, and major and trace element geochemistry in AND-2A show that relatively large polythermal ice-sheets similar in size to the modern were already present between 17.6 and 17.1 Ma. These results are in agreement with proxy records suggesting that Antarctic ice volumes were larger than today’s volume during the Mi-1b glaciation. Between 17.1 and 15.6-14.9 Ma, a predominance of iceberg debris sourced from the Ferrar Group in the Transantarctic Mountains suggests vigorous glacial erosion and fjord incision by East Antarctic outlet glaciers. The facies characteristics and comparison with compositional data from Neogene tills in the Transantarctic Mountains further suggest that the East Antarctic ice sheet may have been smaller than today during the Miocene climatic optimum (~17-15 Ma) with ice possibly reaching sea level only near the central Transantarctic Mountains. Advance of the grounding line and the development of glacial flow patterns compatible with a larger ice sheet than the modern commenced between 15.6 and 14.7 Ma and was established prior to 14.2 Ma. These results suggest an earlier onset of Antarctic ice growth across the middle Miocene climate transition than is generally inferred from geochemical proxy records.

Microstructural characterization and simulation of damage for geared sheet components

NASA Astrophysics Data System (ADS)

Gerstein, G.; Isik, K.; Gutknecht, F.; Sieczkarek, P.; Ewert, J.; Tekkaya, A. E.; Clausmeyer, T.; Nürnberger, F.

2017-09-01

The evolution of damage in geared components manufactured from steel sheets was investigated, to analyse the influence of damage caused by the sheet-bulk-metal forming. Due to the inhomogeneous and multi-axial deformation in the investigated parts, different aspects such as the location-dependent shape and size of voids are analysed by means of various microscopic methods. In particular, a method to characterize the state of damage evolution, i. e. void nucleation, growth and coalescence using scanning electron microscopy (SEM) is applied. The investigations reveal a strong dependence of the void area fraction, shape of voids and thus damage evolution on the loading mode. The microstructural analysis is complemented with FEM simulations using material models which consider the characteristics of the void evolution.

Atomically thin two-dimensional organic-inorganic hybrid perovskites

NASA Astrophysics Data System (ADS)

Dou, Letian; Wong, Andrew B.; Yu, Yi; Lai, Minliang; Kornienko, Nikolay; Eaton, Samuel W.; Fu, Anthony; Bischak, Connor G.; Ma, Jie; Ding, Tina; Ginsberg, Naomi S.; Wang, Lin-Wang; Alivisatos, A. Paul; Yang, Peidong

2015-09-01

Organic-inorganic hybrid perovskites, which have proved to be promising semiconductor materials for photovoltaic applications, have been made into atomically thin two-dimensional (2D) sheets. We report the solution-phase growth of single- and few-unit-cell-thick single-crystalline 2D hybrid perovskites of (C4H9NH3)2PbBr4 with well-defined square shape and large size. In contrast to other 2D materials, the hybrid perovskite sheets exhibit an unusual structural relaxation, and this structural change leads to a band gap shift as compared to the bulk crystal. The high-quality 2D crystals exhibit efficient photoluminescence, and color tuning could be achieved by changing sheet thickness as well as composition via the synthesis of related materials.

Light Sheet Fluorescence Microscopy Quantifies Calcium Oscillations in Root Hairs of Arabidopsis thaliana.

PubMed

Candeo, Alessia; Doccula, Fabrizio G; Valentini, Gianluca; Bassi, Andrea; Costa, Alex

2017-07-01

Calcium oscillations play a role in the regulation of the development of tip-growing plant cells. Using optical microscopy, calcium oscillations have been observed in a few systems (e.g. pollen tubes, fungal hyphae and algal rhizoids). High-resolution, non-phototoxic and rapid imaging methods are required to study the calcium oscillation in root hairs. We show that light sheet fluorescence microscopy is optimal to image growing root hairs of Arabidopsis thaliana and to follow their oscillatory tip-focused calcium gradient. We describe a protocol for performing live imaging of root hairs in seedlings expressing the cytosol-localized ratiometric calcium indicator Yellow Cameleon 3.6. Using this protocol, we measured the calcium gradient in a large number of root hairs. We characterized their calcium oscillations and correlated them with the rate of hair growth. The method was then used to screen the effect of auxin on the properties of the growing root hairs. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists.

Wind for Schools Project Curriculum Brief (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2010-08-01

The U.S. Department of Energy's (DOE's) 20% Wind Energy by 2030 report recommends expanding education to ensure a trained workforce to meet the projected growth of the wind industry and deployment. Although a few U.S. higher education institutions offer wind technology education programs, most are found in community and technical colleges, resulting in a shortage of programs preparing highly skilled graduates for wind industry careers. Further, the United States lags behind Europe (which has more graduate programs in wind technology design and manufacturing) and is in danger of relinquishing the economic benefits of domestic production of wind turbines and relatedmore » components and services to European countries. DOE's Wind Powering America initiative launched the Wind for Schools project to develop a wind energy knowledge base among future leaders of our communities, states, and nation while raising awareness about wind energy's benefits. This fact sheet provides an overview of wind energy curricula as it relates to the Wind for Schools project.« less

Development of a current sheet in the wake of a fast coronal mass ejection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ling, A. G.; Webb, D. F.; Burkepile, J. T.

2014-04-01

A bright ray that developed in the wake of a fast coronal mass ejection (CME) on 2005 September 7 presents a unique opportunity to study the early development and physical characteristics of a reconnecting current sheet (CS). Polarization brightness images from the Mk4 K-Coronameter at the Mauna Loa Solar Observatory are used to determine the structure of the ray along its axis low in the corona as it progressed outward. Coverage of the early development of the ray out to ∼1.3 R {sub ☉} for a period of ∼27 hr after the start of the event enables for the firstmore » time in white light a measurement of a CME CS from the top of the arcade to the base of the flux rope. Measured widths of the ray are combined to obtain the kinematics of the upper and lower {sup Y-}points described in reconnection flux-rope models such as that of Lin and Forbes. The time dependence of these points are used to derive values for the speed and acceleration of the growth of the CS. We note the appearance of a large structure which increases in size as it expands outward in the early development of the ray and an apparent oscillation with a period of ∼0.5 hr in the position angle of the ray.« less

Fact Sheets from the ERIC Clearinghouse on Handicapped and Gifted Children, 1980.

ERIC Educational Resources Information Center

ERIC Clearinghouse on Handicapped and Gifted Children, Reston, VA.

The document is a compilation of 15 fact sheets developed during 1980 by the ERIC Clearinghouse on Handicapped and Gifted Children. Fact sheets are single sheets which provide basic information in a question-answer format and include additional resources and references. The fact sheets have the following titles: "Sex Education for Retarded…

Concerns Boys Have about Puberty

MedlinePlus

... a normal part of the growth process. Wet Dreams Boys may wake up in the morning to ... in their pajama pants and sheets. These " wet dreams ," or nocturnal emissions, are caused by an ejaculation, ...

Expression of an Exogenous Growth Hormone Gene by Transplantable Human Epidermal Cells

NASA Astrophysics Data System (ADS)

Morgan, Jeffrey R.; Barrandon, Yann; Green, Howard; Mulligan, Richard C.

1987-09-01

Retrovirus-mediated gene transfer was used to introduce a recombinant human growth hormone gene into cultured human keratinocytes. The transduced keratinocytes secreted biologically active growth hormone into the culture medium. When grafted as an epithelial sheet onto athymic mice, these cultured keratinocytes reconstituted an epidermis that was similar in appearance to that resulting from normal cells, but from which human growth hormone could be extracted. Transduced epidermal cells may prove to be a general vehicle for the delivery of gene products by means of grafting.

Low-Frequency Waves in the Near-Earth Magnetotail before Substorm Expansion Onsets

NASA Astrophysics Data System (ADS)

Miyashita, Y.; Saito, M. H.; Hiraki, Y.; Machida, S.

2013-12-01

Magnetic reconnection and dipolarization, which occur in the near-Earth magnetotail just before substorm expansion onsets, are important processes for the substorm triggering. To understand the triggering of these processes, we have investigated low-frequency waves that were observed in the near-Earth magnetotail before onsets, by performing statistical analysis based on Geotail observations and case studies based on multi-point THEMIS and Geotail observations. Here we focused our examination on ~10 min interval before onsets. We find that small-amplitude Alfven and slow-mode magnetosonic waves with a period of ~1 to 2 min continuously exist for more than 10 min before onsets. Such waves are seen not only in the initial dipolarization region but also midway between the magnetic reconnection and initial dipolarization regions. It seems that the amplitudes of the waves are larger in the off-equator plasma sheet and the plasma sheet boundary layer than at the magnetic equator and in the lobe. After onsets the waves considerably amplify in the plasma sheet. These results may imply that instabilities already begin to grow gradually in a wide region during the substorm growth phase, while their explosive growth begins in localized regions just before onsets.

Myosin II activity is required for functional leading-edge cells and closure of epidermal sheets in fish skin ex vivo.

PubMed

Morita, Toshiyuki; Tsuchiya, Akiko; Sugimoto, Masazumi

2011-09-01

Re-epithelialization in skin wound healing is a process in which epidermal sheets grow and close the wound. Although the actin-myosin system is thought to have a pivotal role in re-epithelialization, its role is not clear. In fish skin, re-epithelialization occurs around 500 μm/h and is 50 times faster than in mammalian skin. We had previously reported that leading-edge cells of the epidermal outgrowth have both polarized large lamellipodia and "purse string"-like actin filament cables in the scale-skin culture system of medaka fish, Oryzias latipes (Cell Tissue Res, 2007). The actin purse-string (APS) is a supracellular contractile machinery in which adherens junctions (AJs) link intracellular myosin II-including actin cables between neighboring cells. In this study, we developed a modified "face-to-face" scale-skin culture system as an ex vivo model to study epidermal wound healing, and examined the role of the actin-myosin system in the rapid re-epithelialization using a myosin II ATPase inhibitor, blebbistatin. A low level of blebbistatin suppressed the formation of APS and induced the dissociation of keratocytes from the leading edge without attenuating the growth of the epidermal sheet or the migration rate of solitary keratocytes. AJs in the superficial layer showed no obvious changes elicited by blebbistatin. However, two epidermal sheets without APSs did not make a closure with each other, which was confirmed by inhibiting the connecting AJs between the superficial layers. These results suggest that myosin II activity is required for functional leading-edge cells and for epidermal closure.

Influence of solvent composition on the performance of carbodiimide cross-linked gelatin carriers for retinal sheet delivery.

PubMed

Lai, Jui-Yang

2013-09-01

Gelatin is a protein molecule that displays bioaffinity and provides a template to guide retinal pigment epithelial (RPE) cell organization and growth. We have recently demonstrated that the carbodiimide cross-linked gelatin membranes can be used as retinal sheet carriers. The purpose of this work was to further determine the role of solvent composition in the tissue delivery performance of chemically modified biopolymer matrices. The gelatin molecules were treated with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) in the presence of binary ethanol/water mixtures with varying ethanol concentrations (70-95 vol%) to obtain the carriers with different cross-linking efficiencies and mechanical properties. Results of melting point measurements and in vitro degradation tests showed that when the cross-linking index reached a high level of around 45 %, the EDC cross-linked gelatin materials have sufficient thermal stability and resistance to enzymatic degradation, indicating their suitability for the development of carriers for retinal sheet delivery. Irrespective of the solvent composition, the chemically modified gelatin samples are compatible toward human RPE cells without causing toxicity and inflammation. In particular, the membrane carriers prepared by the cross-linking in the presence of solvent mixtures containing 80-90 vol% of ethanol have no impact on the proliferative capacity of ARPE-19 cultures and possess good efficiency in transferring and encapsulating the retinal tissues. It is concluded that, except for cell viability and pro-inflammatory cytokine expression, the retinal sheet delivery performance strongly depends on the solvent composition for EDC cross-linking of gelatin molecules.

Growth of plants on the Late Weichselian ice-sheet during Greenland interstadial-1?

NASA Astrophysics Data System (ADS)

Zale, R.; Huang, Y.-T.; Bigler, C.; Wood, J. R.; Dalén, L.; Wang, X.-R.; Segerström, U.; Klaminder, J.

2018-04-01

Unglaciated forelands and summits protruding from ice-sheets are commonly portrayed as areas where plants first establish at the end of glacial cycles. But is this prevailing view of ice-free refugia too simplistic? Here, we present findings suggesting that surface debris supported plant communities far beyond the rim of the Late Weichselian Ice-sheet during Greenland interstadial 1 (GI-1 or Bølling-Allerød interstadial). We base our interpretations upon findings from terrigenous sediments largely resembling 'plant-trash' deposits in North America (known to form as vegetation established on stagnant ice became buried along with glacial debris during the deglaciation). In our studied deposit, we found macrofossils (N = 10) overlapping with the deglaciation period of the area (9.5-10 cal kyr BP) as well as samples (N = 2) with ages ranging between 12.9 and 13.3 cal kyr BP. The latter ages indicate growth of at least graminoids during the GI-1 interstadial when the site was near the geographic center of the degrading ice-sheet. We suggest that exposure of englacial material during GI-1 created patches of supraglacial debris capable of supporting vascular plants three millennia before deglaciation. The composition and resilience of this early plant community remain uncertain. Yet, the younger group of macrofossils, in combination with pollen and ancient DNA analyses of inclusions, imply that shrubs (Salix sp., Betula sp. and Ericaceae sp) and even tree species (Larix) were present in the debris during the final deglaciation stage.

Hybird state of the tail mangetic configuration during steady convection events

NASA Technical Reports Server (NTRS)

Sergeev, V. A.; Pulkkinen, T. I.; Pellinen, T. I.; Tsyganenko, N. A.

1994-01-01

Previous observations have shown that during periods of steady magnetospheric convection (SMC) a large amount of magnetic flux crosses the plasma sheet (corresponding to approximately 10 deg wide auroral oval at the nightside) and that the magnetic configuration in the midtail is relaxed (the curent sheet is thick and contains enhanced B(sub Z). These signatures are typical for the substorm recovery phase. Using near-geostationary magnetic field data, magnetic field modeling and a noval diagostic technique (isotropic boundary algorithm), we show that in the near-Earth tail the magnetic confirguration is very stretched during the SMC events. This stretching is caused by an intense, thin westward current. Because of the srongly depressed B(sub Z), there is a large radial gradient in the near-tail magetic field. These signatures have been peviously associated only with the substorm growth phase. Our results indicate that during the SMC periods the magnetic configuration is very peculiar, with co-existing thin near-Earth current sheet and thick midtail plasma sheet. The deep local minimum of the equatorial B(sub Z) that devleops at R approximately 12 R(sub E) is consistent with steady, adiabatic, Earthward convection in the midtail. These results impose contraints on the existing substorm theories, and call for an explanation of how such a stressed configuration can persist for such a long time without tail current disruptions that occur at the end of a substorm growth phase.

Structured plasma sheet thinning observed by Galileo and 1984-129

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reeves, G.D.; Belian, R.D.; Fritz, T.A.

On December 8, 1990, the Galileo spacecraft used the Earth for a gravity assist on its way to Jupiter. Its trajectory was such that is crossed geosynchronous orbit at approximately local midnight between 1900 and 2000 UT. At the same time, spacecraft 1984-129 was also located at geosynchronous orbit near local midnight. Several flux dropout events were observed when the two spacecraft were in the near-Earth plasma sheet in the same local time sector. Flux dropout events are associated with plasma sheet thinning in the near-Earth tail during the growth phase of substorms. This period is unique in that Galileomore » provided a rapid radial profile of the near-Earth plasma sheet while 1984-129 provided an azimuthal profile. With measurements from these two spacecraft the authors can distinguish between spatial structures and temporal changes. Their observations confirm that the geosynchronous flux dropout events are consistent with plasma sheet thinning which changes the spacecraft`s magnetic connection from the trapping region to the more distant plasma sheet. However, for this period, thinning occurred on two spatial and temporal scales. The geosynchronous dropouts were highly localized phenomena of 30 min duration superimposed on a more global reconfiguration of the tail lasting approximately 4 hours. 28 refs., 10 figs.« less

Transition from Ignition to Flame Growth under External Radiation in Three Dimensions (TIGER-3D)

NASA Technical Reports Server (NTRS)

Kashiwagi, Takashi; Nakamura, Yuji; Olson, Sandra L.; Mell, William

2004-01-01

This study focuses on localized ignition by external radiant flux and subsequent flame growth over thin polymeric materials (plastic and paper) in microgravity. Two transition stages were observed. The first transition stage covers the period from the onset of ignition to the formation of stabilized flame near the ignited area. This is followed by the second transition of the flame growth stage from the initial stabilized flame to sustained fire growth away from the ignited area. For the first stage, ignition experiments of thin PMMA sheets were conducted using a CO2 laser as an external source in the 10 s drop tower. The results of front side surface ignition and of backside surface ignition were observed. The effects of imposed flow velocity, sample thickness, and ambient oxygen concentration on ignition are obtained. Numerical study was conducted to investigate to understand and predict ignition behavior observed in the experiments. For the second stage, numerical study is being conducted to describe the effects of gravity on heat release rate of a PMMA sheet. The gravity level was varied from zero to normal gravity. The preliminary results show that the maximum heat release occurs at around 0.02 g.

Origins and Transport of Ions during Magnetospheric Substorms

NASA Technical Reports Server (NTRS)

Ashour-Abdalla, Maha; El-Alaoui, Mostafa; Peroomian, Vahe; Raeder, Joachim; Walker, Ray J.; Frank, L. A.; Paterson, W. R.

1999-01-01

We investigate the origins and the transport of ions observed in the near-Earth plasma sheet during the growth and expansion phases of a magnetospheric substorm that occurred on November 24, 1996. Ions observed at Geotail were traced backward in time in time-dependent magnetic and electric fields to determine their origins and the acceleration mechanisms responsible for their energization. Results from this investigation indicate that, during the growth phase of the substorm, most of the ions reaching Geotail had origins in the low latitude boundary layer (LLBL) and had alread@, entered the magnetosphere when the growth phase began. Late in the growth phase and in the expansion phase a higher proportion of the ions reaching Geotail had their origin in the plasma mantle. Indeed, during the expansion phase more than 90% of the ions seen by Geotail were from the mantle. The ions were accelerated enroute to the spacecraft; however, most of the ions' energy gain was achieved by non-adiabatic acceleration while crossing the equatorial current sheet just prior to their detection by Geotail. In general, the plasma mantle from both southern and northern hemispheres supplied non-adiabatic ions to Geotail, whereas the LLBL supplied mostly adiabatic ions to the distributions measured by the spacecraft.

Transition from Ignition to Flame Growth under External Radiation in 3D

NASA Technical Reports Server (NTRS)

Kashiwagi, Takashi; Nakamura, Yuji; Mell, William E.; Olson, Sandra L.

2004-01-01

This study focuses on localized ignition by external radiant flux and subsequent flame growth over thin polymeric materials (plastic and paper) in microgravity. Two transition stages were observed. The first transition stage covers the period from the onset of ignition to the formation of stabilized flame near the ignited area. This is followed by the second transition of the flame growth stage from the initial stabilized flame to sustained fire growth away from the ignited area. For the first stage, ignition experiments of thin PMMA sheets were conducted using a CO2 laser as an external source in the 10 s drop tower. The results of front side surface ignition and of backside surface ignition were observed. The effects of imposed flow velocity, sample thickness, and ambient oxygen concentration on ignition are obtained. Numerical study was conducted to investigate to understand and predict ignition behavior observed in the experiments. For the second stage, numerical study is being conducted to describe the effects of gravity on heat release rate of a PMMA sheet. The gravity level was varied from zero to normal gravity. The preliminary results show that the maximum heat release occurs at around 0.02 g.

LIVVkit: An extensible, python-based, land ice verification and validation toolkit for ice sheet models

NASA Astrophysics Data System (ADS)

Kennedy, Joseph H.; Bennett, Andrew R.; Evans, Katherine J.; Price, Stephen; Hoffman, Matthew; Lipscomb, William H.; Fyke, Jeremy; Vargo, Lauren; Boghozian, Adrianna; Norman, Matthew; Worley, Patrick H.

2017-06-01

To address the pressing need to better understand the behavior and complex interaction of ice sheets within the global Earth system, significant development of continental-scale, dynamical ice sheet models is underway. Concurrent to the development of the Community Ice Sheet Model (CISM), the corresponding verification and validation (V&V) process is being coordinated through a new, robust, Python-based extensible software package, the Land Ice Verification and Validation toolkit (LIVVkit). Incorporated into the typical ice sheet model development cycle, it provides robust and automated numerical verification, software verification, performance validation, and physical validation analyses on a variety of platforms, from personal laptops to the largest supercomputers. LIVVkit operates on sets of regression test and reference data sets, and provides comparisons for a suite of community prioritized tests, including configuration and parameter variations, bit-for-bit evaluation, and plots of model variables to indicate where differences occur. LIVVkit also provides an easily extensible framework to incorporate and analyze results of new intercomparison projects, new observation data, and new computing platforms. LIVVkit is designed for quick adaptation to additional ice sheet models via abstraction of model specific code, functions, and configurations into an ice sheet model description bundle outside the main LIVVkit structure. Ultimately, through shareable and accessible analysis output, LIVVkit is intended to help developers build confidence in their models and enhance the credibility of ice sheet models overall.

Inviscid spatial stability of a compressible mixing layer. II - The flame sheet model

NASA Technical Reports Server (NTRS)

Jackson, T. L.; Grosch, C. E.

1990-01-01

The results of an inviscid spatial calculation for a compressible reacting mixing layer are reported. The limit of infinitive activation energy is taken and the diffusion flame is approximated by a flame sheet. Results are reported for the phase speeds of the neutral waves and maximum growth rates of the unstable waves as a function of the parameters of the problem: the ratio of the temperature of the stationary stream to that of the moving stream, the Mach number of the moving streams, the heat release per unit mass fraction of the reactant, the equivalence ratio of the reaction, and the frequency of the disturbance. These results are compared to the phase speeds and growth rates of the corresponding nonreacting mixing layer. We show that the addition of combustion has important and complex effects on the flow stability.

Vertically oriented arrays of ReS 2 nanosheets for electrochemical energy storage and electrocatalysis

DOE PAGES

Gao, Jian; Li, Lu; Tan, Jiawei; ...

2016-05-17

Here, transition-metal dichalcogenide (TMD) nanolayers show potential as high-performance catalysts in energy conversion and storage devices. Synthetic TMDs produced by chemical-vapor deposition (CVD) methods tend to grow parallel to the growth substrate. Here, we show that with the right precursors and appropriate tuning of the CVD growth conditions, ReS 2 nanosheets can be made to orient perpendicular to the growth substrate. This accomplishes two important objectives; first, it drastically increases the wetted or exposed surface area of the ReS 2 sheets, and second, it exposes the sharp edges and corners of the ReS 2 sheets. We show that these structuralmore » features of the vertically grown ReS 2 sheets can be exploited to significantly improve their performance as polysulfide immobilizers and electrochemical catalysts in lithium–sulfur (Li–S) batteries and in hydrogen evolution reactions (HER). After 300 cycles, the specific capacity of the Li–S battery with vertical ReS 2 catalyst is retained above 750 mA h g –1, with only ~0.063% capacity decay per cycle, much better than the baseline battery (without ReS 2), which shows ~0.184% capacity decay per cycle under the same test conditions. As a HER catalyst, the vertical ReS 2 provides very small onset overpotential (<100 mV) and an exceptional exchange-current density (~67.6 μA/cm 2), which is vastly superior to the baseline electrode without ReS 2.« less

Bioglass Activated Skin Tissue Engineering Constructs for Wound Healing.

PubMed

Yu, Hongfei; Peng, Jinliang; Xu, Yuhong; Chang, Jiang; Li, Haiyan

2016-01-13

Wound healing is a complicated process, and fibroblast is a major cell type that participates in the process. Recent studies have shown that bioglass (BG) can stimulate fibroblasts to secrete a multitude of growth factors that are critical for wound healing. Therefore, we hypothesize that BG can stimulate fibroblasts to have a higher bioactivity by secreting more bioactive growth factors and proteins as compared to untreated fibroblasts, and we aim to construct a bioactive skin tissue engineering graft for wound healing by using BG activated fibroblast sheet. Thus, the effects of BG on fibroblast behaviors were studied, and the bioactive skin tissue engineering grafts containing BG activated fibroblasts were applied to repair the full skin lesions on nude mouse. Results showed that BG stimulated fibroblasts to express some critical growth factors and important proteins including vascular endothelial growth factor, basic fibroblast growth factor, epidermal growth factor, collagen I, and fibronectin. In vivo results revealed that fibroblasts in the bioactive skin tissue engineering grafts migrated into wound bed, and the migration ability of fibroblasts was stimulated by BG. In addition, the bioactive BG activated fibroblast skin tissue engineering grafts could largely increase the blood vessel formation, enhance the production of collagen I, and stimulate the differentiation of fibroblasts into myofibroblasts in the wound site, which would finally accelerate wound healing. This study demonstrates that the BG activated skin tissue engineering grafts contain more critical growth factors and extracellular matrix proteins that are beneficial for wound healing as compared to untreated fibroblast cell sheets.

Custom-shaping system for bone regeneration by seeding marrow stromal cells onto a web-like biodegradable hybrid sheet.

PubMed

Tsuchiya, Kohei; Mori, Taisuke; Chen, Guoping; Ushida, Takashi; Tateishi, Tetsuya; Matsuno, Takeo; Sakamoto, Michiie; Umezawa, Akihiro

2004-05-01

New bone for the repair or the restoration of the function of traumatized, damaged, or lost bone is a major clinical need, and bone tissue engineering has been heralded as an alternative strategy for regenerating bone. A novel web-like structured biodegradable hybrid sheet has been developed for bone tissue engineering by preparing knitted poly(DL-lactic-co-glycolic acid) sheets (PLGA sheets) with collagen microsponges in their openings. The PLGA skeleton facilitates the formation of the hybrid sheets into desired shapes, and the collagen microsponges in the pores of the PLGA sheet promote cell adhesion and uniform cell distribution throughout the sheet. A large number of osteoblasts established from marrow stroma adhere to the scaffolds and generate the desired-shaped bone in combination with these novel sheets. These results indicate that the web-like structured novel sheet shows promise for use as a tool for custom-shaped bone regeneration in basic research on osteogenesis and for the development of therapeutic applications. Copyright 2004 Springer-Verlag

Orientation and spread of reconnection x-line in asymmetric current sheets

NASA Astrophysics Data System (ADS)

Liu, Y. H.; Hesse, M.; Wendel, D. E.; Kuznetsova, M.; Wang, S.

2017-12-01

The magnetic field in solar wind plasmas can shear with Earth's dipole magnetic field at arbitrary angles, and the plasma conditions on the two sides of the (magnetopause) current sheet can greatly differ. One of the outstanding questions in such asymmetric geometry is what local physics controls the orientation of the reconnection x-line; while the x-line in a simplified 2D model (simulation) always points out of the simulation plane by design, it is unclear how to predict the orientation of the x-line in a fully three-dimensional (3D) system. Using kinetic simulations run on Blue Waters, we develop an approach to explore this 3D nature of the reconnection x-line, and test hypotheses including maximizing the reconnection rate, tearing mode growth rate or reconnection outflow speed, and the bisection solution. Practically, this orientation should correspond to the M-direction of the local LMN coordinate system that is often employed to analyze diffusion region crossings by the Magnetospheric Multiscale Mission (MMS). In this talk, we will also discuss how an x-line spread from a point source in asymmetric geometries, and the boundary effect on the development of the reconnection x-line and turbulence.

A coarse grained protein model with internal degrees of freedom. Application to α-synuclein aggregation

NASA Astrophysics Data System (ADS)

Ilie, Ioana M.; den Otter, Wouter K.; Briels, Wim J.

2016-02-01

Particles in simulations are traditionally endowed with fixed interactions. While this is appropriate for particles representing atoms or molecules, objects with significant internal dynamics—like sequences of amino acids or even an entire protein—are poorly modelled by invariable particles. We develop a highly coarse grained polymorph patchy particle with the ultimate aim of simulating proteins as chains of particles at the secondary structure level. Conformational changes, e.g., a transition between disordered and β-sheet states, are accommodated by internal coordinates that determine the shape and interaction characteristics of the particles. The internal coordinates, as well as the particle positions and orientations, are propagated by Brownian Dynamics in response to their local environment. As an example of the potential offered by polymorph particles, we model the amyloidogenic intrinsically disordered protein α-synuclein, involved in Parkinson's disease, as a single particle with two internal states. The simulations yield oligomers of particles in the disordered state and fibrils of particles in the "misfolded" cross-β-sheet state. The aggregation dynamics is complex, as aggregates can form by a direct nucleation-and-growth mechanism and by two-step-nucleation through conversions between the two cluster types. The aggregation dynamics is complex, with fibrils formed by direct nucleation-and-growth, by two-step-nucleation through the conversion of an oligomer and by auto-catalysis of this conversion.

Wrinkling instability of an inhomogeneously stretched viscous sheet

NASA Astrophysics Data System (ADS)

Srinivasan, Siddarth; Wei, Zhiyan; Mahadevan, L.

2017-07-01

Motivated by the redrawing of hot glass into thin sheets, we investigate the shape and stability of a thin viscous sheet that is inhomogeneously stretched in an imposed nonuniform temperature field. We first determine the associated base flow by solving the long-time-scale stretching flow of a flat sheet as a function of two dimensionless parameters: the normalized stretching velocity α and a dimensionless width of the heating zone β . This allows us to determine the conditions for the onset of an out-of-plane wrinkling instability stated in terms of an eigenvalue problem for a linear partial differential equation governing the displacement of the midsurface of the sheet. We show that the sheet can become unstable in two regions that are upstream and downstream of the heating zone where the minimum in-plane stress is negative. This yields the shape and growth rates of the most unstable buckling mode in both regions for various values of the stretching velocity and heating zone width. A transition from stationary to oscillatory unstable modes is found in the upstream region with increasing β , while the downstream region is always stationary. We show that the wrinkling instability can be entirely suppressed when the surface tension is large enough relative to the magnitude of the in-plane stress. Finally, we present an operating diagram that indicates regions of the parameter space that result in a required outlet sheet thickness upon stretching while simultaneously minimizing or suppressing the out-of-plane buckling, a result that is relevant for the glass redraw method used to create ultrathin glass sheets.

Application technologies for effective utilization of advanced high strength steel sheets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suehiro, Masayoshi, E-mail: suehiro.kp5.masayoshi@jp.nssmc.com

Recently, application of high strength steel sheets for automobiles has increased in order to meet a demand of light weighting of automobiles to reduce a carbon footprint while satisfying collision safety. The formability of steel sheets generally decreases with the increase in strength. Fracture and wrinkles tend to occur easily during forming. The springback phenomenon is also one of the issues which we should cope with, because it makes it difficult to obtain the desired shape after forming. Advanced high strength steel sheets with high formability have been developed in order to overcome these issues, and at the same timemore » application technologies have been developed for their effective utilization. These sheets are normally used for cold forming. As a different type of forming, hot forming technique has been developed in order to produce parts with ultra high strength. In this report, technologies developed at NSSMC in this field will be introduced.« less

Graphene oxide--MnO2 nanocomposites for supercapacitors.

PubMed

Chen, Sheng; Zhu, Junwu; Wu, Xiaodong; Han, Qiaofeng; Wang, Xin

2010-05-25

A composite of graphene oxide supported by needle-like MnO(2) nanocrystals (GO-MnO(2) nanocomposites) has been fabricated through a simple soft chemical route in a water-isopropyl alcohol system. The formation mechanism of these intriguing nanocomposites investigated by transmission electron microscopy and Raman and ultraviolet-visible absorption spectroscopy is proposed as intercalation and adsorption of manganese ions onto the GO sheets, followed by the nucleation and growth of the crystal species in a double solvent system via dissolution-crystallization and oriented attachment mechanisms, which in turn results in the exfoliation of GO sheets. Interestingly, it was found that the electrochemical performance of as-prepared nanocomposites could be enhanced by the chemical interaction between GO and MnO(2). This method provides a facile and straightforward approach to deposit MnO(2) nanoparticles onto the graphene oxide sheets (single layer of graphite oxide) and may be readily extended to the preparation of other classes of hybrids based on GO sheets for technological applications.

Human iPS cell-engineered cardiac tissue sheets with cardiomyocytes and vascular cells for cardiac regeneration

PubMed Central

Masumoto, Hidetoshi; Ikuno, Takeshi; Takeda, Masafumi; Fukushima, Hiroyuki; Marui, Akira; Katayama, Shiori; Shimizu, Tatsuya; Ikeda, Tadashi; Okano, Teruo; Sakata, Ryuzo; Yamashita, Jun K.

2014-01-01

To realize cardiac regeneration using human induced pluripotent stem cells (hiPSCs), strategies for cell preparation, tissue engineering and transplantation must be explored. Here we report a new protocol for the simultaneous induction of cardiomyocytes (CMs) and vascular cells [endothelial cells (ECs)/vascular mural cells (MCs)], and generate entirely hiPSC-engineered cardiovascular cell sheets, which showed advantageous therapeutic effects in infarcted hearts. The protocol adds to a previous differentiation protocol of CMs by using stage-specific supplementation of vascular endothelial cell growth factor for the additional induction of vascular cells. Using this cell sheet technology, we successfully generated physically integrated cardiac tissue sheets (hiPSC-CTSs). HiPSC-CTS transplantation to rat infarcted hearts significantly improved cardiac function. In addition to neovascularization, we confirmed that engrafted human cells mainly consisted of CMs in >40% of transplanted rats four weeks after transplantation. Thus, our HiPSC-CTSs show promise for cardiac regenerative therapy. PMID:25336194

Mass balance of the Antarctic ice sheet.

PubMed

Wingham, D J; Shepherd, A; Muir, A; Marshall, G J

2006-07-15

The Antarctic contribution to sea-level rise has long been uncertain. While regional variability in ice dynamics has been revealed, a picture of mass changes throughout the continental ice sheet is lacking. Here, we use satellite radar altimetry to measure the elevation change of 72% of the grounded ice sheet during the period 1992-2003. Depending on the density of the snow giving rise to the observed elevation fluctuations, the ice sheet mass trend falls in the range -5-+85Gtyr-1. We find that data from climate model reanalyses are not able to characterise the contemporary snowfall fluctuation with useful accuracy and our best estimate of the overall mass trend-growth of 27+/-29Gtyr-1-is based on an assessment of the expected snowfall variability. Mass gains from accumulating snow, particularly on the Antarctic Peninsula and within East Antarctica, exceed the ice dynamic mass loss from West Antarctica. The result exacerbates the difficulty of explaining twentieth century sea-level rise.

Experimental analysis of the sheet metal forming behavior of newly developed press hardening steels

NASA Astrophysics Data System (ADS)

Meza-García, Enrique; Kräusel, Verena; Landgrebe, Dirk

2018-05-01

The aim of this work was the characterization of the newly developed press hardening sheet alloys 1800 PHS and 2000 PHS developed by SSAB with regard to their hot forming behavior on the basis of the experimental determination of relevant mechanical and technological properties. For this purpose conventional and non-conventional sheet metal testing methods were used. To determine the friction coefficient, the strip drawing test was applied, while the deep drawing cup test was used to determine the maximum draw depth. Finally, a V-bending test was carried out to evaluate the springback behavior of the investigated alloys by varying the blank temperature and quenching media. This work provides a technological guideline for the production of press hardened sheet parts made of these investigated sheet metals.

Spatial and temporal features of the growth of a bacterial species colonizing the zebrafish gut.

PubMed

Jemielita, Matthew; Taormina, Michael J; Burns, Adam R; Hampton, Jennifer S; Rolig, Annah S; Guillemin, Karen; Parthasarathy, Raghuveer

2014-12-16

The vertebrate intestine is home to microbial ecosystems that play key roles in host development and health. Little is known about the spatial and temporal dynamics of these microbial communities, limiting our understanding of fundamental properties, such as their mechanisms of growth, propagation, and persistence. To address this, we inoculated initially germ-free zebrafish larvae with fluorescently labeled strains of an Aeromonas species, representing an abundant genus in the zebrafish gut. Using light sheet fluorescence microscopy to obtain three-dimensional images spanning the gut, we quantified the entire bacterial load, as founding populations grew from tens to tens of thousands of cells over several hours. The data yield the first ever measurements of the growth kinetics of a microbial species inside a live vertebrate intestine and show dynamics that robustly fit a logistic growth model. Intriguingly, bacteria were nonuniformly distributed throughout the gut, and bacterial aggregates showed considerably higher growth rates than did discrete individuals. The form of aggregate growth indicates intrinsically higher division rates for clustered bacteria, rather than surface-mediated agglomeration onto clusters. Thus, the spatial organization of gut bacteria both relative to the host and to each other impacts overall growth kinetics, suggesting that spatial characterizations will be an important input to predictive models of host-associated microbial community assembly. Our intestines are home to vast numbers of microbes that influence many aspects of health and disease. Though we now know a great deal about the constituents of the gut microbiota, we understand very little about their spatial structure and temporal dynamics in humans or in any animal: how microbial populations establish themselves, grow, fluctuate, and persist. To address this, we made use of a model organism, the zebrafish, and a new optical imaging technique, light sheet fluorescence microscopy, to visualize for the first time the colonization of a live, vertebrate gut by specific bacteria with sufficient resolution to quantify the population over a range from a few individuals to tens of thousands of bacterial cells. Our results provide unprecedented measures of bacterial growth kinetics and also show the influence of spatial structure on bacterial populations, which can be revealed only by direct imaging. Copyright © 2014 Jemielita et al.

On Growth and Form of the Zebrafish Gut Microbiome

NASA Astrophysics Data System (ADS)

Jemielita, Matthew; Taormina, Michael; Rolig, Annah; Burns, Adam; Hampton, Jennifer; Guillemin, Karen; Parthasarathy, Raghuveer

2014-03-01

The vertebrate gut is home to a diverse microbial community whose composition has a strong influence on the development and health of the host organism. Researchers can identify the members of the microbiota, yet little is known about the spatial and temporal dynamics of these microbial communities, including the mechanisms guiding their nucleation, growth, and interactions. We address these issues using the larval zebrafish (Danio rerio) as a model organism, which are raised microbe-free and then inoculated with controlled compositions of fluorophore-expressing bacteria. Live imaging using light sheet fluorescence microscopy enables visualization of the gut's entire microbial population over the first 24 hours of colonization. Image analysis allows us to quantify microbial populations that range from a few individuals to tens of thousands of microbes, and analyze the structure and growth kinetics of gut bacterial communities. We find that genetically-identical microbes can show surprisingly different growth rates and colonization abilities depending on their order of arrival. This demonstrates that knowing only the constituents of the gut community is insufficient to determine their dynamics; rather, the history of colonization matters.

Capabilities and performance of the new generation ice-sheet model Elmer/Ice

NASA Astrophysics Data System (ADS)

Gagliardini, O.; Zwinger, T.; Durand, G.; Favier, L.; de Fleurian, B.; Gillet-chaulet, F.; Seddik, H.; Greve, R.; Mallinen, M.; Martin, C.; Raback, P.; Ruokolainen, J.; Schäfer, M.; Thies, J.

2012-12-01

Since the Fourth IPCC Assessment Report, and its conclusion about the inability of ice-sheet flow models to forecast the current increase of polar ice sheet discharge and associated contribution to sea-level rise, a huge development effort has been undertaken by the glaciological community. All around the world, models have been improved and, interestingly, a significant number of new ice-sheet models have emerged. Among them, the parallel finite-element model Elmer/Ice (based on the open-source multi-physics code Elmer) was one of the first full-Stokes models used to make projections of the future of the whole Greenland ice sheet for the coming two centuries. Originally developed to solve dedicated local ice flow problems of high mechanical and physical complexity, Elmer/Ice has today reached the maturity to solve larger scale problems, earning the status of an ice-sheet model. In this presentation, we summarise the almost 10 years of development performed by different groups. We present the components already included in Elmer/Ice, its numerical performance, selected applications, as well as developments planed for the future.

Capabilities and performance of Elmer/Ice, a new generation ice-sheet model

NASA Astrophysics Data System (ADS)

Gagliardini, O.; Zwinger, T.; Gillet-Chaulet, F.; Durand, G.; Favier, L.; de Fleurian, B.; Greve, R.; Malinen, M.; Martín, C.; Råback, P.; Ruokolainen, J.; Sacchettini, M.; Schäfer, M.; Seddik, H.; Thies, J.

2013-03-01

The Fourth IPCC Assessment Report concluded that ice-sheet flow models are unable to forecast the current increase of polar ice sheet discharge and the associated contribution to sea-level rise. Since then, the glaciological community has undertaken a huge effort to develop and improve a new generation of ice-flow models, and as a result, a significant number of new ice-sheet models have emerged. Among them is the parallel finite-element model Elmer/Ice, based on the open-source multi-physics code Elmer. It was one of the first full-Stokes models used to make projections for the evolution of the whole Greenland ice sheet for the coming two centuries. Originally developed to solve local ice flow problems of high mechanical and physical complexity, Elmer/Ice has today reached the maturity to solve larger scale problems, earning the status of an ice-sheet model. Here, we summarise almost 10 yr of development performed by different groups. We present the components already included in Elmer/Ice, its numerical performance, selected applications, as well as developments planned for the future.

Structural and Electrical Characteristics of Carbon Nanowalls Synthesized on the Polyimide Film.

PubMed

Kwon, Seok Hun; Kim, Hyung Jin; Choi, Won Seok; Kang, Hyunil

2018-09-01

In this study, the structural and electrical characteristics of carbon nanowalls (CNWs) synthesized on polyimide films were investigated. CNWs were synthesized on polyimide films as various growth times. The cross-section and surface of the CNWs synthesized were examined using FE-SEM. The growth and defects of CNWs were observed by raman spectrum. The hall measurement system was used to analyzed sheet resistance, resistivity and conductivity. The CNWs synthesized at 40 minutes showed outstanding structural and electrical characterizations than another growth times.

Decorating graphene oxide with CuO nanoparticles in a water-isopropanol system.

PubMed

Zhu, Junwu; Zeng, Guiyu; Nie, Fude; Xu, Xiaoming; Chen, Sheng; Han, Qiaofeng; Wang, Xin

2010-06-01

A facile chemical procedure capable of aligning CuO nanoparticles on graphene oxide (GO) in a water-isopropanol system has been described. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) observations indicate that the exfoliated GO sheets are decorated randomly by spindly or spherical CuO nanoparticle aggregates, forming well-ordered CuO:GO nanocomposites. A formation mechanism of these interesting nanocomposites is proposed as intercalation and adsorption of Cu2+ ions onto the GO sheets, followed by the nucleation and growth of the CuO crystallites, which in return resulted in the exfoliation of GO sheets. Moreover, the obtained nanocomposites exhibit a high catalytic activity for the thermal decomposition of ammonium perchlorate (AP), due to the concerted effect of CuO and GO.

Atomically thin two-dimensional organic-inorganic hybrid perovskites.

PubMed

Dou, Letian; Wong, Andrew B; Yu, Yi; Lai, Minliang; Kornienko, Nikolay; Eaton, Samuel W; Fu, Anthony; Bischak, Connor G; Ma, Jie; Ding, Tina; Ginsberg, Naomi S; Wang, Lin-Wang; Alivisatos, A Paul; Yang, Peidong

2015-09-25

Organic-inorganic hybrid perovskites, which have proved to be promising semiconductor materials for photovoltaic applications, have been made into atomically thin two-dimensional (2D) sheets. We report the solution-phase growth of single- and few-unit-cell-thick single-crystalline 2D hybrid perovskites of (C4H9NH3)2PbBr4 with well-defined square shape and large size. In contrast to other 2D materials, the hybrid perovskite sheets exhibit an unusual structural relaxation, and this structural change leads to a band gap shift as compared to the bulk crystal. The high-quality 2D crystals exhibit efficient photoluminescence, and color tuning could be achieved by changing sheet thickness as well as composition via the synthesis of related materials. Copyright © 2015, American Association for the Advancement of Science.

Polycrystalline silicon sheets for solar cells by the spinning method

NASA Astrophysics Data System (ADS)

Maeda, Y.; Yokoyama, T.; Hide, I.

1984-03-01

A new method has been developed in which polycrystalline silicon sheets are formed directly from molten silicon on a spinning wheel. The sheet is 5 cm x 5 cm, 0.1-0.5 mm thick, and made at a rate of four sheets per 15 s; power conversion rate of a solar cell assembled with these silicon sheets is more than 10 percent.

Elevation Change of the Southern Greenland Ice Sheet from Satellite Radar Altimeter Data

NASA Technical Reports Server (NTRS)

Haines, Bruce J.

1999-01-01

Long-term changes in the thickness of the polar ice sheets are important indicators of climate change. Understanding the contributions to the global water mass balance from the accumulation or ablation of grounded ice in Greenland and Antarctica is considered crucial for determining the source of the about 2 mm/yr sea-level rise in the last century. Though the Antarctic ice sheet is much larger than its northern counterpart, the Greenland ice sheet is more likely to undergo dramatic changes in response to a warming trend. This can be attributed to the warmer Greenland climate, as well as a potential for amplification of a global warming trend in the polar regions of the Northern Hemisphere. In collaboration with Drs. Curt Davis and Craig Kluever of the University of Missouri, we are using data from satellite radar altimeters to measure changes in the elevation of the Southern Greenland ice sheet from 1978 to the present. Difficulties with systematic altimeter measurement errors, particularly in intersatellite comparisons, beset earlier studies of the Greenland ice sheet thickness. We use altimeter data collected contemporaneously over the global ocean to establish a reference for correcting ice-sheet data. In addition, the waveform data from the ice-sheet radar returns are reprocessed to better determine the range from the satellite to the ice surface. At JPL, we are focusing our efforts principally on the reduction of orbit errors and range biases in the measurement systems on the various altimeter missions. Our approach emphasizes global characterization and reduction of the long-period orbit errors and range biases using altimeter data from NASA's Ocean Pathfinder program. Along-track sea-height residuals are sequentially filtered and backwards smoothed, and the radial orbit errors are modeled as sinusoids with a wavelength equal to one revolution of the satellite. The amplitudes of the sinusoids are treated as exponentially-correlated noise processes with a time-constant of six days. Measurement errors (e.g., altimeter range bias) are simultaneously recovered as constant parameters. The corrections derived from the global ocean analysis are then applied over the Greenland ice sheet. The orbit error and measurement bias corrections for different missions are developed in a single framework to enable robust linkage of ice-sheet measurements from 1978 to the present. In 1998, we completed our re-evaluation of the 1978 Seasat and 1985-1989 Geosat Exact Repeat Mission data. The estimates of ice thickness over Southern Greenland (south of 72N and above 2000 m) from 1978 to 1988 show large regional variations (+/-18 cm/yr), but yield an overall rate of +1.5 +/- 0.5 cm/yr (one standard error). Accounting for systematic errors, the estimate may not be significantly different from the null growth rate. The average elevation change from 1978 to 1988 is too small to assess whether the Greenland ice sheet is undergoing a long-term change.

Skill Sheets for Agricultural Mechanics.

ERIC Educational Resources Information Center

Iowa State Univ. of Science and Technology, Ames. Dept. of Agricultural Education.

This set of 33 skill sheets for agricultural mechanics was developed for use in high school and vocational school agricultural mechanics programs. Some sheets teach operational procedures while others are for simple projects. Each skill sheet covers a single topic and includes: (1) a diagram, (2) a step-by-step construction or operational…

Developing methods based on light sheet fluorescence microscopy for biophysical investigations of larval zebrafish

NASA Astrophysics Data System (ADS)

Taormina, Michael J.

Adapting the tools of optical microscopy to the large-scale dynamic systems encountered in the development of multicellular organisms provides a path toward understanding the physical processes necessary for complex life to form and function. Obtaining quantitatively meaningful results from such systems has been challenging due to difficulty spanning the spatial and temporal scales representative of the whole, while also observing the many individual members from which complex and collective behavior emerges. A three-dimensional imaging technique known as light sheet fluorescence microscopy provides a number of significant benefits for surmounting these challenges and studying developmental systems. A thin plane of fluorescence excitation light is produced such that it coincides with the focal plane of an imaging system, providing rapid acquisition of optically sectioned images that can be used to construct a three-dimensional rendition of a sample. I discuss the implementation of this technique for use in larva of the model vertebrate Danio rerio (zebrafish). The nature of light sheet imaging makes it especially well suited to the study of large systems while maintaining good spatial resolution and minimizing damage to the specimen from excessive exposure to excitation light. I show the results from a comparative study that demonstrates the ability to image certain developmental processes non-destructively, while in contrast confocal microscopy results in abnormal growth due to phototoxicity. I develop the application of light sheet microscopy to the study of a previously inaccessible system: the bacterial colonization of a host organism. Using the technique, we are able to obtain a survey of the intestinal tract of a larval zebrafish and observe the location of microbes as they grow and establish a stable population in an initially germ free fish. Finally, I describe a new technique to measure the fluid viscosity of this intestinal environment in vivo using magnetically driven particles. By imaging such particles as they are oscillated in a frequency chirped field, it is possible to calculate properties such as the viscosity of the material in which they are embedded. Here I provide the first known measurement of intestinal mucus rheology in vivo.

The performance of fast-moving low-voltage electromechanical actuators based on single-walled carbon nanotubes and ionic liquids

NASA Astrophysics Data System (ADS)

Mukai, Ken; Asaka, Kinji; Hata, Kenji; Oike, Hideaki

2011-12-01

In this paper, we study the details of the mechanical and electrical properties of polymer-free single-walled carbon nanotube (SWNT) sheets containing different contents of ionic liquids (ILs). The polymer-free SWNT sheets were prepared by a previously reported finding that millimeter-long 'super-growth' carbon nanotubes (SG-SWNTs), produced by a water-assisted modified chemical vapor deposition (CVD) method, associate together tightly with ILs, affording a free-standing sheet with a superb conductivity. The Young's modulus, breaking strength and the electrical conductivity of the SG-SWNT sheet with 67 wt% 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMITFSI) showed large values, 0.63 GPa, 20 MPa, and 147 S cm-1, respectively, although it has large amounts of ILs. We also measure the frequency dependence of the displacement of the actuator composed of SG-SWNT sheets sandwiching an ionic-gel electrolyte layer (SG-SWNT actuator). At more than 50 wt% of EMITFSI content, the frequency response of the actuation of the SG-SWNT actuator is flat up to around 100 Hz. The results of the displacement measurements are discussed in relation to the mechanical and electrical properties of the SG-SWNT actuators.

Sea-level records from the U.S. mid-Atlantic constrain Laurentide Ice Sheet extent during Marine Isotope Stage 3

PubMed Central

Pico, T; Creveling, J. R.; Mitrovica, J. X.

2017-01-01

The U.S. mid-Atlantic sea-level record is sensitive to the history of the Laurentide Ice Sheet as the coastline lies along the ice sheet's peripheral bulge. However, paleo sea-level markers on the present-day shoreline of Virginia and North Carolina dated to Marine Isotope Stage (MIS) 3, from 50 to 35 ka, are surprisingly high for this glacial interval, and remain unexplained by previous models of ice age adjustment or other local (for example, tectonic) effects. Here, we reconcile this sea-level record using a revised model of glacial isostatic adjustment characterized by a peak global mean sea level during MIS 3 of approximately −40 m, and far less ice volume within the eastern sector of the Laurentide Ice Sheet than traditional reconstructions for this interval. We conclude that the Laurentide Ice Sheet experienced a phase of very rapid growth in the 15 kyr leading into the Last Glacial Maximum, thus highlighting the potential of mid-field sea-level records to constrain areal extent of ice cover during glacial intervals with sparse geological observables. PMID:28555637

Effect of debond growth on stress-intensity factors in a cracked orthotropic sheet stiffened by a semi-infinite orthotropic sheet

NASA Technical Reports Server (NTRS)

Bigelow, C. A.

1986-01-01

Stress-intensity factors are determined for a cracked infinite sheet adhesively bonded to a stringer, and debonding of the adhesive layer is predicted. The stringer is modeled as a semi-infinite sheet. Adhesive nonlinearity is also included. Both the sheet and stringer are treated as homogeneous, orthotropic materials. A set of integral equations is formulated and solved to obtain the adhesive shear stresses and crack-tip stress-intensity factors. Adhesive debonding is predicted using a rupture criterion based on the combined adhesive stresses. When the crack is not under the stringer, the debond extends along the edge of the stringer. When the crack tip is beneath the stringer, the debond grows to the end of the crack, then along the edge of the stringer. Stress levels required for debond initiation decrease as the crack tip is moved beneath the stringer. With a nonlinear adhesive, the debond initiates at higher applied stress levels than in linear adhesive cases. Compared with the linear adhesive solution, modeling a nonlinear adhesive causes the stress-intensity factor to increase when the bond is assumed to remain intact but causes the stress-intensity factor to decrease when debonding is included.

Fracture Test Methods for Plastically Responding COPV Liners

NASA Technical Reports Server (NTRS)

Dawicke, David S.; Lewis, Joseph C.

2009-01-01

An experimental procedure for evaluating the validity of using uniaxial tests to provide a conservative bound on the fatigue crack growth rate behavior small cracks in bi-axially loaded Composite Overwrapped Pressure Vessel (COPV) liners is described. The experimental procedure included the use of a laser notch to quickly generate small surface fatigue cracks with the desired size and aspect ratios. An out-of-plane constraint system was designed to allow fully reversed, fully plastic testing of thin sheet uniaxial coupons. Finally, a method was developed to determine to initiate small cracks in the liner of COPVs.

Evolution of supra-glacial lakes across the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Sundal, A. V.; Shepherd, A.; Nienow, P.; Hanna, E.; Palmer, S.; Huybrechts, P.

2009-04-01

We have used 268 cloud-free Moderate-resolution Imaging Spectroradiometer (MODIS) images spanning the 2003 and 2005-2007 melt seasons to study the seasonal evolution of supra-glacial lakes in three different regions of the Greenland Ice Sheet. Lake area estimates were obtained by developing an automated classification method for their identification based on 250 m resolution MODIS surface reflectance observations. Widespread supra-glacial lake formation and drainage is observed across the ice sheet, with a 2-3 weeks delay in the evolution of total supra-glacial lake area in the northern areas compared to the south-west. The onset of lake growth varies by up to one month inter-annually, and lakes form and drain at progressively higher altitudes during the melt season. A correlation was found between the annual peak in total lake area and modelled annual runoff across all study areas. Our results indicate that, in a future warmer climate (Meehl et al., 2007), Greenland supra-glacial lakes can be expected to form at higher altitudes and over a longer time period than is presently the case, expanding the area and time period over which connections between the ice sheet surface and base may be established (Das et al., 2008) with potential consequences for ice sheet discharge (Zwally et al., 2002). Das, S., Joughin, M., Behn, M., Howat, I., King, M., Lizarralde, D., & Bhatia, M. (2008). Fracture propagation to the base of the Greenland Ice Sheet during supra-glacial lake drainage. Science, 5877, 778-781. Meehl, G.A., Stocker, T.F., Collins W.D., Friedlingstein, P., Gaye, A.T., Gregory, J.M., Kitoh, A., Knutti, R., Murphy, J.M., Noda, A., Raper, S.C.B., Watterson, I.G., Weaver, A.J. & Zhao, Z.C. (2007). Global Climate Projections. In: Climate Change 2007: The Physical Science Basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change [Solomon, S., D. Qin, M. Manning, Z. Chen, M. Marquis, K.B. Averyt, M. Tignor and H.L. Miller (eds.)]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. Zwally, H.J., Abdalati, W., Herring, T., Larson, K., Saba, J. & Steffen, K. (2002). Surface Melt-Induced Acceleration of Greenland Ice-Sheet Flow. Science, 297, 218-221.

LIVVkit: An extensible, python-based, land ice verification and validation toolkit for ice sheet models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kennedy, Joseph H.; Bennett, Andrew R.; Evans, Katherine J.

To address the pressing need to better understand the behavior and complex interaction of ice sheets within the global Earth system, significant development of continental-scale, dynamical ice sheet models is underway. Concurrent to the development of the Community Ice Sheet Model (CISM), the corresponding verification and validation (V&V) process is being coordinated through a new, robust, Python-based extensible software package, the Land Ice Verification and Validation toolkit (LIVVkit). Incorporated into the typical ice sheet model development cycle, it provides robust and automated numerical verification, software verification, performance validation, and physical validation analyses on a variety of platforms, from personal laptopsmore » to the largest supercomputers. LIVVkit operates on sets of regression test and reference data sets, and provides comparisons for a suite of community prioritized tests, including configuration and parameter variations, bit-for-bit evaluation, and plots of model variables to indicate where differences occur. LIVVkit also provides an easily extensible framework to incorporate and analyze results of new intercomparison projects, new observation data, and new computing platforms. LIVVkit is designed for quick adaptation to additional ice sheet models via abstraction of model specific code, functions, and configurations into an ice sheet model description bundle outside the main LIVVkit structure. Furthermore, through shareable and accessible analysis output, LIVVkit is intended to help developers build confidence in their models and enhance the credibility of ice sheet models overall.« less

LIVVkit: An extensible, python-based, land ice verification and validation toolkit for ice sheet models

DOE PAGES

Kennedy, Joseph H.; Bennett, Andrew R.; Evans, Katherine J.; ...

2017-03-23

To address the pressing need to better understand the behavior and complex interaction of ice sheets within the global Earth system, significant development of continental-scale, dynamical ice sheet models is underway. Concurrent to the development of the Community Ice Sheet Model (CISM), the corresponding verification and validation (V&V) process is being coordinated through a new, robust, Python-based extensible software package, the Land Ice Verification and Validation toolkit (LIVVkit). Incorporated into the typical ice sheet model development cycle, it provides robust and automated numerical verification, software verification, performance validation, and physical validation analyses on a variety of platforms, from personal laptopsmore » to the largest supercomputers. LIVVkit operates on sets of regression test and reference data sets, and provides comparisons for a suite of community prioritized tests, including configuration and parameter variations, bit-for-bit evaluation, and plots of model variables to indicate where differences occur. LIVVkit also provides an easily extensible framework to incorporate and analyze results of new intercomparison projects, new observation data, and new computing platforms. LIVVkit is designed for quick adaptation to additional ice sheet models via abstraction of model specific code, functions, and configurations into an ice sheet model description bundle outside the main LIVVkit structure. Furthermore, through shareable and accessible analysis output, LIVVkit is intended to help developers build confidence in their models and enhance the credibility of ice sheet models overall.« less

High-Power Growth-Robust InGaAs/InAlAs Terahertz Quantum Cascade Lasers

PubMed Central

2017-01-01

We report on high-power terahertz quantum cascade lasers based on low effective electron mass InGaAs/InAlAs semiconductor heterostructures with excellent reproducibility. Growth-related asymmetries in the form of interface roughness and dopant migration play a crucial role in this material system. These bias polarity dependent phenomena are studied using a nominally symmetric active region resulting in a preferential electron transport in the growth direction. A structure based on a three-well optical phonon depletion scheme was optimized for this bias direction. Depending on the sheet doping density, the performance of this structure shows a trade-off between high maximum operating temperature and high output power. While the highest operating temperature of 155 K is observed for a moderate sheet doping density of 2 × 1010 cm–2, the highest peak output power of 151 mW is found for 7.3 × 1010 cm–2. Furthermore, by abutting a hyperhemispherical GaAs lens to a device with the highest doping level a record output power of 587 mW is achieved for double-metal waveguide structures. PMID:28470028

High-Power Growth-Robust InGaAs/InAlAs Terahertz Quantum Cascade Lasers.

PubMed

Deutsch, Christoph; Kainz, Martin Alexander; Krall, Michael; Brandstetter, Martin; Bachmann, Dominic; Schönhuber, Sebastian; Detz, Hermann; Zederbauer, Tobias; MacFarland, Donald; Andrews, Aaron Maxwell; Schrenk, Werner; Beck, Mattias; Ohtani, Keita; Faist, Jérôme; Strasser, Gottfried; Unterrainer, Karl

2017-04-19

We report on high-power terahertz quantum cascade lasers based on low effective electron mass InGaAs/InAlAs semiconductor heterostructures with excellent reproducibility. Growth-related asymmetries in the form of interface roughness and dopant migration play a crucial role in this material system. These bias polarity dependent phenomena are studied using a nominally symmetric active region resulting in a preferential electron transport in the growth direction. A structure based on a three-well optical phonon depletion scheme was optimized for this bias direction. Depending on the sheet doping density, the performance of this structure shows a trade-off between high maximum operating temperature and high output power. While the highest operating temperature of 155 K is observed for a moderate sheet doping density of 2 × 10 10 cm -2 , the highest peak output power of 151 mW is found for 7.3 × 10 10 cm -2 . Furthermore, by abutting a hyperhemispherical GaAs lens to a device with the highest doping level a record output power of 587 mW is achieved for double-metal waveguide structures.

The Impact of Wind Development on County-Level Income and Employment: A Review of Methods and an Empirical Analysis (Fact Sheet). Wind And Water Power Program (WWPP).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Jason P.; Pender, John; Wiser, Ryan

2012-09-02

The economic development potential from wind power installations has been a driver of public and policy support for the industry at the local and state levels for many years. The possibility for economic development has been particularly salient in rural areas of the country where new investment, earnings growth, and employment opportunities have, in many cases, otherwise trended downward for some time. Despite frequent mention of the economic development potential of wind power projects, however, questions persist on the magnitude, distribution, and durability of these impacts. Of particular concern for rural communities is whether new investment in wind power projectsmore » stimulates long-term local economic growth and employment. Questions about the economic development and employment impacts of wind power also persist at the national level. However, such debates tend to be more concerned with potential economic losses associated with displacement of other energy sources or land uses and the macroeconomic effects of policy support for renewable energy and changes in electricity rates that might result from wind energy deployment. The present analysis focuses solely on county-level impacts.« less

Development of a new surgical sheet containing both silk fibroin and thermoplastic polyurethane for cardiovascular surgery.

PubMed

Shimada, Ryo; Konishi, Hayato; Ozawa, Hideki; Katsumata, Takahiro; Tanaka, Ryou; Nakazawa, Yasumoto; Nemoto, Shintaro

2018-05-01

The surgical sheets that are currently used for congenital cardiovascular surgery have several drawbacks, including material deterioration, calcification, and pseudo-intimal proliferation resulting in hemodynamic disturbance. The aim of this study was to evaluate a newly developed sheet made from a combination of silk fibroin (SF) and a synthetic polymer, thermoplastic polyurethane (TPU), for surgical use. The hybrid SF/TPU sheet was a non-woven fabric with nanofibers that was made using the electrospinning method. The mechanical properties of the SF/TPU sheet were characterized. To determine its biocompatibility, part of the wall of the canine descending aorta was replaced with a SF/TPU sheet as a patch. The patches were removed after 3 months and a histological examination was performed. The flexibility, water permeability, and suture retention strength of the SF/TPU sheet were excellent and equivalent to those of existing sheets. The SF/TPU sheet had excellent handling properties and fit well into the vascular wall without needle hole bleeding. The histological examination revealed that the intimal tissue was restored well over the intraluminal surface of the explanted SF/TPU sheet, the absence of calcium deposition, and minimal inflammatory reaction, without signs of degradation. The SF/TPU sheet had excellent mechanical properties and tissue biocompatibility. These favorable features and possible biodegradability of the SF portion warrant a long-term follow-up study.

Guidance system for low angle silicon ribbon growth

DOEpatents

Jewett, David N.; Bates, Herbert E.; Milstein, Joseph B.

1986-07-08

In a low angle silicon sheet growth process, a puller mechanism advances a seed crystal and solidified ribbon from a cooled growth zone in a melt at a low angle with respect to the horizontal. The ribbon is supported on a ramp adjacent the puller mechanism. Variations in the vertical position of the ribbon with respect to the ramp are isolated from the growth end of the ribbon by (1) growing the ribbon so that it is extremely thin, preferably less than 0.7 mm, (2) maintaining a large growth zone, preferably one whose length is at least 5.0 cm, and (3) spacing the ramp from the growth zone by at least 15 cm.

Inception of the Laurentide Ice Sheet using asynchronous coupling of a regional atmospheric model and an ice model

NASA Astrophysics Data System (ADS)

Birch, L.; Cronin, T.; Tziperman, E.

2017-12-01

The climate over the past 0.8 million years has been dominated by ice ages. Ice sheets have grown about every 100 kyrs, starting from warm interglacials, until they spanned continents. State-of-the-art global climate models (GCMs) have difficulty simulating glacial inception, or the transition of Earth's climate from an interglacial to a glacial state. It has been suggested that this failure may be related to their poorly resolved local mountain topography, due to their coarse spatial resolution. We examine this idea as well as the possible role of ice flow dynamics missing in GCMs. We investigate the growth of the Laurentide Ice Sheet at 115 kya by focusing on the mountain glaciers of Canada's Baffin Island, where geologic evidence indicates the last inception occurred. We use the Weather Research and Forecasting model (WRF) in a regional, cloud-resolving configuration with resolved mountain terrain to explore how quickly Baffin Island could become glaciated with the favorable yet realizable conditions of 115 kya insolation, cool summers, and wet winters. Using the model-derived mountain glacier mass balance, we force an ice sheet model based on the shallow-ice approximation, capturing the ice flow that may be critical to the spread of ice sheets away from mountain ice caps. The ice sheet model calculates the surface area newly covered by ice and the change in the ice surface elevation, which we then use to run WRF again. Through this type of iterated asynchronous coupling, we investigate how the regional climate responds to both larger areas of ice cover and changes in ice surface elevation. In addition, we use the NOAH-MP Land model to characterize the importance of land processes, like refreezing. We find that initial ice growth on the Penny Ice Cap causes regional cooling that increases the accumulation on the Barnes Ice Cap. We investigate how ice and topography changes on Baffin Island may impact both the regional climate and the large-scale circulation.

Mass Changes of the Greenland and Antarctic Ice Sheets and Shelves and Contributions to Sea-level Rise: 1992-2002

NASA Technical Reports Server (NTRS)

Zwally, H. Jay; Giovinetto, Mario B.; Li, Jun; Cornejo, Helen G.; Beckley, Matthew A.; Brenner, Anita C.; Saba, Jack L.; Yi, Donghui

2005-01-01

Changes in ice mass are estimated from elevation changes derived from 10.5 years (Greenland) and 9 years (Antarctica) of satellite radar altimetry data from the European Remote-sensing Satellites ERS-1 and -2. For the first time, the dH/dt values are adjusted for changes in surface elevation resulting from temperature-driven variations in the rate of fun compaction. The Greenland ice sheet is thinning at the margins (-42 plus or minus 2 Gta(sup -1) below the equilibrium line altitude (ELA)) and growing inland (+53 plus or minus 2 Gt a(sup -1)above the ELA) with a small overall mass gain (+11 plus or minus 3 Gt a(sup -1); -0.03 mm a(sup -1) SLE (sea level equivalent)). The ice sheet in West Antarctica (WA) is losing mass (-47 (dot) 4 GT a(sup -1) and the ice sheet in East Antarctica (EA) shows a small mass gain (+16 plus or minus 11 Gt a(sup -1) for a combined net change of -31 plus or minus 12 Gt a(sup -1) (+0.08 mm a(sup -1) SLE)). The contribution of the three ice sheets to sea level is +0.05 plus or minus 0.03 mm a(sup -1). The Antarctic ice shelves show corresponding mass changes of -95 (dot) 11 Gt a(sup -1) in WA and +142 plus or minus 10 Gt a(sup -1) in EA. Thinning at the margins of the Greenland ice sheet and growth at higher elevations is an expected response to increasing temperatures and precipitation in a warming climate. The marked thinnings in the Pine Island and Thwaites Glacier basins of WA and the Totten Glacier basin in EA are probably ice-dynamic responses to long-term climate change and perhaps past removal of their adjacent ice shelves. The ice growth in the southern Antarctic Peninsula and parts of EA may be due to increasing precipitation during the last century.

Clinching for sheet materials

PubMed Central

He, Xiaocong

2017-01-01

Abstract Latest developments in the clinching of sheet materials are reviewed in this article. Important issues are discussed, such as tool design, process parameters and joinability of some new lightweight sheet materials. Hybrid and modified clinching processes are introduced to a general reader. Several unaddressed issues in the clinching of sheet materials are identified. PMID:28656065

Inviscid spatial stability of a compressible mixing layer. Part 2: The flame sheet model

NASA Technical Reports Server (NTRS)

Jackson, T. L.; Grosch, C. E.

1989-01-01

The results of an inviscid spatial calculation for a compressible reacting mixing layer are reported. The limit of infinitive activation energy is taken and the diffusion flame is approximated by a flame sheet. Results are reported for the phase speeds of the neutral waves and maximum growth rates of the unstable waves as a function of the parameters of the problem: the ratio of the temperature of the stationary stream to that of the moving stream, the Mach number of the moving streams, the heat release per unit mass fraction of the reactant, the equivalence ratio of the reaction, and the frequency of the disturbance. These results are compared to the phase speeds and growth rates of the corresponding nonreacting mixing layer. We show that the addition of combustion has important, and complex effects on the flow stability.

High-resistive layers obtained through periodic growth and in situ annealing of InGaN by metalorganic chemical vapor deposition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Shuo; Ma, Ping, E-mail: maping@semi.ac.cn; Liu, Boting

2016-06-15

High-resistive layers were obtained by periodic growth and in situ annealing of InGaN. The effect of the annealing temperature of InGaN on the indium content and the material sheet resistive was investigated. The indium content decreased as the increase of in situ annealing temperature. Additionally, the material sheet resistance increased with the increase of the in situ annealing temperature for the annealed samples and reached 2 × 10{sup 10}Ω/sq in the light and 2 × 10{sup 11}Ω/sq in the dark when the in situ annealing temperature reached 970{sup ∘}C. The acquirement of high-resistive layers is attributed to the generation ofmore » indium vacancy-related defects. Introducing indium vacancy-related defects to compensate background carriers can be an effective method to grow high-resistance material.« less

Electrostatic drift instability in a magnetotail configuration: The role of bouncing electrons

NASA Astrophysics Data System (ADS)

Fruit, G.; Louarn, P.; Tur, A.

2017-03-01

To understand the possible destabilization of two-dimensional current sheets, a kinetic model is proposed to describe the resonant interaction between electrostatic modes and trapped electrons that bounce within the sheet. This work follows the initial investigation by Tur, Louarn, and Yanovsky [Phys. Plasmas 17, 102905 (2010)] and Fruit, Louarn, and Tur [Phys. Plasmas 20, 022113 (2013)] that is revised and extended. Using a quasi-dipolar equilibrium state, the linearized gyro-kinetic Vlasov equation is solved for electrostatic fluctuations with a period of the order of the electron bounce period. Using an appropriated Fourier expansion of the particle motion along the magnetic field, the complete time integration of the non-local perturbed distribution functions is performed. The dispersion relation for electrostatic modes is then obtained through the quasineutrality condition. It is found that for a mildly stretched configuration ( L ˜8 ), strongly unstable electrostatic modes may develop in the current sheet with the growth rate of the order of a few seconds provided that the background density gradient responsible for the diamagnetic drift effects is sharp enough: typical length scale over one Earth radius or less. However, when this condition in the density gradient is not met, these electrostatic modes grow too slowly to be accountable for a rapid destabilization of the magnetic structure. This strong but finely tuned instability may offer opportunities to explain features in magnetospheric substorms.

Slicing of silicon into sheet material. Silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project. Third quarterly report, September 20, 1976--December 19, 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holden, S.C.

1976-12-27

The stability of tensioned blades used in multiblade sawing does not seem to be the limitation in cutting with thin blades. So far, 0.010 cm thick blades have been totally unsuccessful. Recently, 0.015 cm blades have proven successful in wafering, offering an 0.005 cm reduction in the silicon used per slice. The failure of thin blades is characterized as a possible result of blade misalignment or from the inherent uncontrollability of the loose abrasive multiblade process. Corrective procedures will be employed in the assembly of packages to eliminate one type of blade misalignment. Two ingots were sliced with the samemore » batch of standard silicon carbide abrasive slurry to determine the useful lifetime of this expendable material. After 250 slices, the cutting efficiency had not degraded. Further tests will be continued to establish the maximum lifetime of both silicon carbide and boron carbide abrasive. Electron microscopy will be employed to evaluate the wear of abrasive particles in the failure of abrasive slurry. The surface damage of silicon wafers has been characterized as predominantly subsurface fracture. Damage with No. 600 SiC is between 10 and 15 microns into the wafer surface. This agrees well with previous investigations of damage from silicon carbide abrasive papers.« less

Combinatorial effect of substratum properties on mesenchymal stem cell sheet engineering and subsequent multi-lineage differentiation.

PubMed

Chuah, Yon Jin; Zhang, Ying; Wu, Yingnan; Menon, Nishanth V; Goh, Ghim Hian; Lee, Ann Charlene; Chan, Vincent; Zhang, Yilei; Kang, Yuejun

2015-09-01

Cell sheet engineering has been exploited as an alternative approach in tissue regeneration and the use of stem cells to generate cell sheets has further showed its potential in stem cell-mediated tissue regeneration. There exist vast interests in developing strategies to enhance the formation of stem cell sheets for downstream applications. It has been proved that stem cells are sensitive to the biophysical cues of the microenvironment. Therefore we hypothesized that the combinatorial substratum properties could be tailored to modulate the development of cell sheet formation and further influence its multipotency. For validation, polydimethylsiloxane (PDMS) of different combinatorial substratum properties (including stiffness, roughness and wettability) were created, on which the human bone marrow derived mesenchymal stem cells (BMSCs) were cultured to form cell sheets with their multipotency evaluated after induced differentiation. The results showed that different combinatorial effects of these substratum properties were able to influence BMSC behavior such as adhesion, spreading and proliferation during cell sheet development. Collagen formation within the cell sheet was enhanced on substrates with lower stiffness, higher hydrophobicity and roughness, which further assisted the induced chondrogenesis and osteogenesis, respectively. These findings suggested that combinatorial substratum properties had profound effects on BMSC cell sheet integrity and multipotency, which had significant implications for future biomaterials and scaffold designs in the field of BMSC-mediated tissue regeneration. Copyright © 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity.

PubMed

Wei, Fulan; Qu, Cunye; Song, Tieli; Ding, Gang; Fan, Zhipeng; Liu, Dayong; Liu, Yi; Zhang, Chunmei; Shi, Songtao; Wang, Songlin

2012-09-01

Cell sheet engineering has been developed as an alternative approach to improve mesenchymal stem cell-mediated tissue regeneration. In this study, we found that vitamin C (Vc) was capable of inducing telomerase activity in periodontal ligament stem cells (PDLSCs), leading to the up-regulated expression of extracellular matrix type I collagen, fibronectin, and integrin β1, stem cell markers Oct4, Sox2, and Nanog as well as osteogenic markers RUNX2, ALP, OCN. Under Vc treatment, PDLSCs can form cell sheet structures because of increased cell matrix production. Interestingly, PDLSC sheets demonstrated a significant improvement in tissue regeneration compared with untreated control dissociated PDLSCs and offered an effective treatment for periodontal defects in a swine model. In addition, bone marrow mesenchymal stem cell sheets and umbilical cord mesenchymal stem cell sheets were also well constructed using this method. The development of Vc-mediated mesenchymal stem cell sheets may provide an easy and practical approach for cell-based tissue regeneration. Copyright © 2011 Wiley Periodicals, Inc.

Experimental investigation of a 1 kA/cm² sheet beam plasma cathode electron gun.

PubMed

Kumar, Niraj; Pal, Udit Narayan; Pal, Dharmendra Kumar; Prajesh, Rahul; Prakash, Ram

2015-01-01

In this paper, a cold cathode based sheet-beam plasma cathode electron gun is reported with achieved sheet-beam current density ∼1 kA/cm(2) from pseudospark based argon plasma for pulse length of ∼200 ns in a single shot experiment. For the qualitative assessment of the sheet-beam, an arrangement of three isolated metallic-sheets is proposed. The actual shape and size of the sheet-electron-beam are obtained through a non-conventional method by proposing a dielectric charging technique and scanning electron microscope based imaging. As distinct from the earlier developed sheet beam sources, the generated sheet-beam has been propagated more than 190 mm distance in a drift space region maintaining sheet structure without assistance of any external magnetic field.

Development of the apparatus for measuring magnetic properties of electrical steel sheets in arbitrary directions under compressive stress normal to their surface

NASA Astrophysics Data System (ADS)

Maeda, Yoshitaka; Urata, Shinya; Nakai, Hideo; Takeuchi, Yuuya; Yun, Kyyoul; Yanase, Shunji; Okazaki, Yasuo

2017-05-01

In designing motors, one must grasp the magnetic properties of electrical steel sheets considering actual conditions in motors. Especially important is grasping the stress dependence of magnetic power loss. This paper describes a newly developed apparatus to measure two-dimensional (2-D) magnetic properties (properties under the arbitrary alternating and the rotating flux conditions) of electrical steel sheets under compressive stress normal to the sheet surface. The apparatus has a 2-D magnetic excitation circuit to generate magnetic fields in arbitrary directions in the evaluation area. It also has a pressing unit to apply compressive stress normal to the sheet surface. During measurement, it is important to apply uniform stress throughout the evaluation area. Therefore, we have developed a new flux density sensor using needle probe method. It is composed of thin copper foils sputtered on electrical steel sheets. By using this sensor, the stress can be applied to the surface of the specimen without influence of this sensor. This paper described the details of newly developed apparatus with this sensor, and measurement results of iron loss by using are shown.

Twin-Mirrored-Galvanometer Laser-Light-Sheet Generator

NASA Technical Reports Server (NTRS)

Rhodes, David B.; Franke, John M.; Jones, Stephen B.; Leighty, Bradley D.

1991-01-01

Multiple, rotating laser-light sheets generated to illuminate flows in wind tunnels. Designed and developed to provide flexibility and adaptability to wide range of applications. Design includes capability to control size and location of laser-light sheet in real time, to generate horizontal or vertical sheets, to sweep sheet repeatedly through volume, to generate multiple sheets with controllable separation, and to rotate single or multiple laser-light sheets. Includes electronic equipment and laser mounted on adjustable-height platform. Twin-mirrored galvanometer unit supported by tripod to reduce vibration. Other possible applications include use in construction industry to align beams of building. Artistic or display applications also possible.

Antarctic glacial history from numerical models and continental margin sediments

USGS Publications Warehouse

Barker, P.F.; Barrett, P.J.; Cooper, A. K.; Huybrechts, P.

1999-01-01

The climate record of glacially transported sediments in prograded wedges around the Antarctic outer continental shelf, and their derivatives in continental rise drifts, may be combined to produce an Antarctic ice sheet history, using numerical models of ice sheet response to temperature and sea-level change. Examination of published models suggests several preliminary conclusions about ice sheet history. The ice sheet's present high sensitivity to sea-level change at short (orbital) periods was developed gradually as its size increased, replacing a declining sensitivity to temperature. Models suggest that the ice sheet grew abruptly to 40% (or possibly more) of its present size at the Eocene-Oligocene boundary, mainly as a result of its own temperature sensitivity. A large but more gradual middle Miocene change was externally driven, probably by development of the Antarctic Circumpolar Current (ACC) and Polar Front, provided that a few million years' delay can be explained. The Oligocene ice sheet varied considerably in size and areal extent, but the late Miocene ice sheet was more stable, though significantly warmer than today's. This difference probably relates to the confining effect of the Antarctic continental margin. Present-day numerical models of ice sheet development are sufficient to guide current sampling plans, but sea-ice formation, polar wander, basal topography and ice streaming can be identified as factors meriting additional modelling effort in the future.

Spectroscopic studies on the conformational transitions of a bovine growth hormone releasing factor analog

NASA Astrophysics Data System (ADS)

Sarver, Ronald W.; Friedman, Alan R.; Thamann, Thomas J.

1997-10-01

The secondary structure of the bovine growth hormone releasing factor analog, [Ile 2, Ser 8,28, Ala 15, Leu 27, Hse 30] bGRF(1-30)-NH-Ethyl, acetate salt (U-90699F) was studied in solution by Fourier transform infrared and Raman spectroscopies. Spectroscopic studies revealed that concentrated aqueous solutions of U-90699F (100 mg ml -1) undergo a secondary structure transition from disordered coil/α-helix to intermolecular β-sheet. Disordered coil and α-helical structure were grouped together in the infrared and Raman studies since the amide I vibrations are close in frequency and overlap in assignments was possible. Before the conformational transition, the facile exchange of the peptide's amide hydrogens for deuterium indicated that the majority of amide hydrogens were readily accessible to solvent. The kinetics of the conformational transition coincided with an increase in solution viscosity and turbidity. An initiation phase preceded the conformational transition during which only minor spectral changes were observed by infrared spectroscopy. The initiation phase and reaction kinetics were consistent with a highly cooperative nucleation ultimately leading to a network of intermolecular β-sheet structure and gel formation. Increased temperature accelerated the conformational transition. The conformational transition was thermally irreversible but the β-sheet structure of aggregated or gelled peptide could be disrupted by dilution and agitation.

Copper intercalation at the interface of graphene and Ir(111) studied by scanning tunneling microscopy

NASA Astrophysics Data System (ADS)

Sicot, M.; Fagot-Revurat, Y.; Kierren, B.; Vasseur, G.; Malterre, D.

2014-11-01

We report on the intercalation of a submonolayer of copper at 775 K underneath graphene epitaxially grown on Ir(111) studied by means of low energy electron diffraction (LEED) and scanning tunneling microscopy (STM) at 77 K. Nucleation and growth dynamics of Cu below graphene have been investigated, and, most importantly, the intercalation mechanism has been identified. First, LEED patterns reveal the pseudomorphic growth of Cu on Ir under the topmost graphene layer resulting in a large Cu in-plane lattice parameter expansion of about 6% compared to Cu(111). Second, large-scale STM topographs as a function of Cu coverage show that Cu diffusion on Ir below graphene exhibits a low energy barrier resulting in Cu accumulation at Ir step edges. As a result, the graphene sheet undergoes a strong edges reshaping. Finally, atomically-resolved STM images reveal a damaged graphene sheet at the atomic scale after metal intercalation. Point defects in graphene were shown to be carbon vacancies. According to these results, a Cu penetration path beneath graphene is proposed to occur via metal aided defect formation with no or poor self healing of the graphene sheet. This work illustrates the fact that Cu intercalation is harmful for graphene grown on Ir(111) at the atomic scale.

Localized tearing modes in the magnetotail driven by curvature effects

NASA Technical Reports Server (NTRS)

Sundaram, A. K.; Fairfield, D. H.

1995-01-01

The stability of collisionless tearing modes is examined in the presence of curvature drift resonances and the trapped particle effects. A kinetic description for both electrons and ions is employed to investigate the stability of a two-dimensional equilibrium model. The main features of the study are to treat the ion dynamics properly by incorporating effects associated with particle trajectories in the tail fields and to include the linear coupling of trapped particle modes. Generalized dispersion relations are derived in several parameter regimes by considering two important sublayers of the reconnecting region. For a typical choice of parameters appropriate to the current sheet region, we demonstrate that localized tearing modes driven by ion curvature drift resonance effects are excited in the current sheet region with growth time of the order of a few seconds. Also, we examine nonlocal characteristics of tearing modes driven by curvature effects and show that modes growing in a fraction of a second arise when mode widths are larger than the current sheet width. Further, we show that trapped particle effects, in an interesting frequency regime, significantly enhance the growth rate of the tearing mode. The relevance of this theory for substorm onset phase and other features of the substorms is briefly discussed.

A general explanation on the correlation of dark matter halo spin with the large-scale environment

NASA Astrophysics Data System (ADS)

Wang, Peng; Kang, Xi

2017-06-01

Both simulations and observations have found that the spin of halo/galaxy is correlated with the large-scale environment, and particularly the spin of halo flips in filament. A consistent picture of halo spin evolution in different environments is still lacked. Using N-body simulation, we find that halo spin with its environment evolves continuously from sheet to cluster, and the flip of halo spin happens both in filament and nodes. The flip in filament can be explained by halo formation time and migrating time when its environment changes from sheet to filament. For low-mass haloes, they form first in sheets and migrate into filaments later, so their mass and spin growth inside filament are lower, and the original spin is still parallel to filament. For high-mass haloes, they migrate into filaments first, and most of their mass and spin growth are obtained in filaments, so the resulted spin is perpendicular to filament. Our results well explain the overall evolution of cosmic web in the cold dark matter model and can be tested using high-redshift data. The scenario can also be tested against alternative models of dark matter, such as warm/hot dark matter, where the structure formation will proceed in a different way.

Intrinsic versus extrinsic controls on the development of calcite dendrite bushes, Shuzhishi Spring, Rehai geothermal area, Tengchong, Yunnan Province, China

NASA Astrophysics Data System (ADS)

Jones, Brian; Peng, Xiaotong

2012-04-01

In the Rehai geothermal area, located near Tengchong, there is an old succession of crystalline calcite that formed from a spring that is no longer active. The thin-bedded succession, exposed on the south bank of Zaotang River, is formed of three-dimensional dendrite bushes that are up to 6 cm high and 3 cm in diameter with multiple levels of branching. Bedding is defined by color, which ranges from white to gray to almost black and locally accentuated by differential weathering that highlights the branching motif of the dendrites. The succession developed through repeated tripartite growth cycles that involved: Phase I that was characterized by rapid vertical growth of the dendrite bushes with ever-increasing branching; Phase II that developed once growth of the dendrites had almost or totally ceased, and involved an initial phase of etching that was followed by the precipitation of various secondary minerals (sheet calcite, trigonal calcite crystals, hexagonal calcite crystals, hexagonal plates formed of Ca and P, Mn precipitates, Si-Mg reticulate coatings, opal-CT lepispheres) on the branches of the calcite dendrites, and Phase III that involved deposition of detrital quartz, feldspar, clay, and calcite on top of the dendrite bushes. The tripartite growth cycle is attributed primarily to aperiodic cycles in the CO2 content of the spring water that was controlled by subsurface igneous activity rather than climatic controls. High CO2 coupled with rapid CO2 degassing triggered growth of the dendrite bushes. As CO2 levels waned, saturation levels in the spring water decreased and calcite dendrite growth ceased and precipitation of the secondary minerals took place, possibly in the microcosms of microbial mats. Deposition of the detrital sediment was probably related to surface runoff that was triggered by periods of high rainfall. Critically, this study shows that intrinsic factors rather than extrinsic factors (e.g., climate) were the prime control on the development of the tripartite growth cycle.

Nickel induced re-structuring of 2D graphene to 1D graphene nanotubes: Role of radical hydrogen in catalyst assisted growth

NASA Astrophysics Data System (ADS)

Krishna, Rahul; Titus, Elby

2017-12-01

Here, we demonstrate for the first time the structural evolution of 1D graphene nanotubes (GNTs) by the cutting of two dimensional (2D) graphene oxide (GO) sheet in reducing environment at ambient conditions in presence of Ni metal in acidic environment. We observed that in-situ generated radical hydrogen (Hrad) responsible for cutting of graphene sheets and re-structuring of 2D sheet structure to one 1D nanotubes. Structural evolution of GNTs was confirmed by using of transmission electron microscopy (TEM) technique. The current vs. voltage (I-V) characteristics of GNTs displayed room temperature (RT) negative differential resistance (NDR) effect which is typical in nanowires, suggested the applicability of nanomaterial for various kind of electronics applications such as memory devices and transistors fabrication.

Using the Global Burden of Disease study to assist development of nation-specific fact sheets to promote prevention and control of hypertension and reduction in dietary salt: a resource from the World Hypertension League.

PubMed

Campbell, Norm R C; Lackland, Daniel T; Lisheng, Liu; Niebylski, Mark L; Nilsson, Peter M; Zhang, Xin-Hua

2015-03-01

Increased blood pressure and high dietary salt are leading risks for death and disability globally. Reducing the burden of both health risks are United Nations' targets for reducing noncommunicable disease. Nongovernmental organizations and individuals can assist by ensuring widespread dissemination of the best available facts and recommended interventions for both health risks. Simple but impactful fact sheets can be useful for informing the public, healthcare professionals, and policy makers. The World Hypertension League has developed fact sheets on dietary salt and hypertension but in many circumstances the greatest impact would be obtained from national-level fact sheets. This manuscript provides instructions and a template for developing fact sheets based on the Global Burden of Disease study and national survey data. ©2015 Wiley Periodicals, Inc.

Fingerprinting of music scores

NASA Astrophysics Data System (ADS)

Irons, Jonathan; Schmucker, Martin

2004-06-01

Publishers of sheet music are generally reluctant in distributing their content via the Internet. Although online sheet music distribution's advantages are numerous the potential risk of Intellectual Property Rights (IPR) infringement, e.g. illegal online distributions, disables any innovation propensity. While active protection techniques only deter external risk factors, additional technology is necessary to adequately treat further risk factors. For several media types including music scores watermarking technology has been developed, which ebeds information in data by suitable data modifications. Furthermore, fingerprinting or perceptual hasing methods have been developed and are being applied especially for audio. These methods allow the identification of content without prior modifications. In this article we motivate the development of watermarking and fingerprinting technologies for sheet music. Outgoing from potential limitations of watermarking methods we explain why fingerprinting methods are important for sheet music and address potential applications. Finally we introduce a condept for fingerprinting of sheet music.

Setting Up a Simple Light Sheet Microscope for In Toto Imaging of C. elegans Development

PubMed Central

Bertrand, Vincent; Lenne, Pierre-François

2014-01-01

Fast and low phototoxic imaging techniques are pre-requisite to study the development of organisms in toto. Light sheet based microscopy reduces photo-bleaching and phototoxic effects compared to confocal microscopy, while providing 3D images with subcellular resolution. Here we present the setup of a light sheet based microscope, which is composed of an upright microscope and a small set of opto-mechanical elements for the generation of the light sheet. The protocol describes how to build, align the microscope and characterize the light sheet. In addition, it details how to implement the method for in toto imaging of C. elegans embryos using a simple observation chamber. The method allows the capture of 3D two-colors time-lapse movies over few hours of development. This should ease the tracking of cell shape, cell divisions and tagged proteins over long periods of time. PMID:24836407

Switching Vertical to Horizontal Graphene Growth Using Faraday Cage-Assisted PECVD Approach for High-Performance Transparent Heating Device.

PubMed

Qi, Yue; Deng, Bing; Guo, Xiao; Chen, Shulin; Gao, Jing; Li, Tianran; Dou, Zhipeng; Ci, Haina; Sun, Jingyu; Chen, Zhaolong; Wang, Ruoyu; Cui, Lingzhi; Chen, Xudong; Chen, Ke; Wang, Huihui; Wang, Sheng; Gao, Peng; Rummeli, Mark H; Peng, Hailin; Zhang, Yanfeng; Liu, Zhongfan

2018-02-01

Plasma-enhanced chemical vapor deposition (PECVD) is an applicable route to achieve low-temperature growth of graphene, typically shaped like vertical nanowalls. However, for transparent electronic applications, the rich exposed edges and high specific surface area of vertical graphene (VG) nanowalls can enhance the carrier scattering and light absorption, resulting in high sheet resistance and low transmittance. Thus, the synthesis of laid-down graphene (LG) is imperative. Here, a Faraday cage is designed to switch graphene growth in PECVD from the vertical to the horizontal direction by weakening ion bombardment and shielding electric field. Consequently, laid-down graphene is synthesized on low-softening-point soda-lime glass (6 cm × 10 cm) at ≈580 °C. This is hardly realized through the conventional PECVD or the thermal chemical vapor deposition methods with the necessity of high growth temperature (1000 °C-1600 °C). Laid-down graphene glass has higher transparency, lower sheet resistance, and much improved macroscopic uniformity when compare to its vertical graphene counterpart and it performs better in transparent heating devices. This will inspire the next-generation applications in low-cost transparent electronics. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Polymorphic Fibrillation of the Destabilized Fourth Fasciclin-1 Domain Mutant A546T of the Transforming Growth Factor-β-induced Protein (TGFBIp) Occurs through Multiple Pathways with Different Oligomeric Intermediates*

PubMed Central

Andreasen, Maria; Nielsen, Søren B.; Runager, Kasper; Christiansen, Gunna; Nielsen, Niels Chr.; Enghild, Jan J.; Otzen, Daniel E.

2012-01-01

Mutations in the transforming growth factor β-induced protein (TGFBIp) are linked to the development of corneal dystrophies in which abnormal protein deposition in the cornea leads to a loss of corneal transparency and ultimately blindness. Different mutations give rise to phenotypically distinct corneal dystrophies. Most mutations are located in the fourth fasciclin-1 domain (FAS1–4). The amino acid substitution A546T in the FAS1–4 domain is linked to the development of lattice corneal dystrophy with amyloid deposits in the superficial and deep stroma, classifying it as an amyloid disease. Here we provide a detailed description of the fibrillation of the isolated FAS1–4 domain carrying the A546T substitution. The A546T substitution leads to a significant destabilization of FAS1–4 and induces a partially folded structure with increased surface exposure of hydrophobic patches. The mutation also leads to two distinct fibril morphologies. Long straight fibrils composed of pure β-sheet structure are formed at lower concentrations, whereas short and curly fibrils containing a mixture of α-helical and β-sheet structures are formed at higher concentrations. The formation of short and curly fibrils is preceded by the formation of a small number of oligomeric species with high membrane permeabilization potential and rapid fibril formation. The long straight fibrils are formed more slowly and through progressively bigger oligomers that lose their membrane permeabilization potential as fibrillation proceeds beyond the lag phase. These different fibril classes and associated biochemical differences may lead to different clinical symptoms associated with the mutation. PMID:22893702

From Tragedy to Triumph - Rebuilding Green Homes after Disaster (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2009-04-01

Energy Efficiency/Renewable Energy Fact Sheets, No. 1. Series to include practical, useful info to help people change their behavior around energy usage and "greenness". Greensburg is hanging its future on sustainable development; these fact sheet sheets should help citizens understand what they can do to be a part of that focus. Fact Sheets cover: saving energy and water, using renewable energy (particular interest in small wind), driving "green", general sustainability, living green.

Simulation of the 3-D Evolution of Electron Scale Magnetic Reconnection - Motivated by Laboratory Experiments Predictions for MMS

NASA Astrophysics Data System (ADS)

Buechner, J.; Jain, N.; Sharma, A.

2013-12-01

The four s/c of the Magnetospheric Multiscale (MMS) mission, to be launched in 2014, will use the Earth's magnetosphere as a laboratory to study the microphysics of three fundamental plasma processes. One of them is magnetic reconnection, an essentially multi-scale process. While laboratory experiments and past theoretical investigations have shown that important processes necessary to understand magnetic reconnection take place at electron scales the MMS mission for the first time will be able to resolve these scales by in space observations. For the measurement strategy of MMS it is important to make specific predictions of the behavior of current sheets with a thickness of the order of the electron skin depth which play an important role in the evolution of collisionless magnetic reconnection. Since these processes are highly nonlinear and non-local numerical simulation is needed to specify the current sheet evolution. Here we present new results about the nonlinear evolution of electron-scale current sheets starting from the linear stage and using 3-D electron-magnetohydrodynamic (EMHD) simulations. The growth rates of the simulated instabilities compared well with the growth rates obtained from linear theory. Mechanisms and conditions of the formation of flux ropes and of current filamentation will be discussed in comparison with the results of fully kinetic simulations. In 3D the X- and O-point configurations of the magnetic field formed in reconnection planes alternate along the out-of-reconnection-plane direction with the wavelength of the unstable mode. In the presence of multiple reconnection sites, the out-of-plane magnetic field can develop nested structure of quadrupoles in reconnection planes, similar to the 2-D case, but now with variations in the out-of-plane direction. The structures of the electron flow and magnetic field in 3-D simulations will be compared with those in 2-D simulations to discriminate the essentially 3D features. We also discuss the influence of guide fields, as in the magnetopause case and show how the 3-D evolution of an electron current sheet is influenced the strength of the guide field. This is unlike the 2-D case where reconnection takes place only in a plane. This work was partially funded by the Max-Planck/Princeton Center for Plasma Physics and the National Science Foundation.

Minority carrier diffusion lengths and absorption coefficients in silicon sheet material

NASA Technical Reports Server (NTRS)

Dumas, K. A.; Swimm, R. T.

1980-01-01

Most of the methods which have been developed for the measurement of the minority carrier diffusion length of silicon wafers require that the material have either a Schottky or an ohmic contact. The surface photovoltage (SPV) technique is an exception. The SPV technique could, therefore, become a valuable diagnostic tool in connection with current efforts to develop low-cost processes for the production of solar cells. The technique depends on a knowledge of the optical absorption coefficient. The considered investigation is concerned with a reevaluation of the absorption coefficient as a function of silicon processing. A comparison of absorption coefficient values showed these values to be relatively consistent from sample to sample, and independent of the sample growth method.

Effects of rolling conditions on recrystallization microstructure and texture in magnetostrictive Fe-Ga-Al rolled sheets

NASA Astrophysics Data System (ADS)

Li, Jiheng; Liu, Yangyang; Li, Xiaojuan; Mu, Xing; Bao, Xiaoqian; Gao, Xuexu

2018-07-01

The effects of different rolling conditions on the microstructure and texture of primary and secondary recrystallization in magnetostrictive Fe82Ga9Al9+0.1at%NbC alloy sheets were investigated. After the primary recrystallization annealing at 850 °C for 5 min, the as-rolled sheets prepared by warm-cold rolling with an intermediate annealing, can be fully recrystallized, and obtain the homogeneous matrix in which the fine dispersed NbC precipitate particles are distributed. The primary recrystallization textures of sheets with different rolling conditions consist mostly of strong {1 0 0} textures, γ-fiber textures, {4 1 1}〈1 4 8〉 texture and weak Goss texture. In the primary recrystallized sheets prepared by warm-cold rolling with an intermediate annealing, the high energy grain boundaries and ∑9 boundaries have the highest proportion. After high temperature annealing, the secondary recrystallizations of Goss grains in these sheets are more complete, and the size of abnormal grown Goss grain is up to several centimeters, which results in the strongest Goss texture. Correspondingly, the largest magnetostriction of 183 ppm is observed. The sample prepared by warm-cold rolling with an intermediate annealing, has homogeneous primary matrix, special texture components and grain boundary distribution, all of which provide a better surrounding for the abnormal growth of Goss grains. This work indicates that the control of rolling conditions of Fe-Ga-Al alloy sheets is necessary to achieve the strong Goss texture and obtain a possible high magnetostriction if other appropriate conditions (stress, domain structure) are achieved.

Transfer of fibroblast sheets cultured on thermoresponsive dishes with membranes.

PubMed

Kawecki, Marek; Kraut, Małgorzata; Klama-Baryła, Agnieszka; Łabuś, Wojciech; Kitala, Diana; Nowak, Mariusz; Glik, Justyna; Sieroń, Aleksander L; Utrata-Wesołek, Alicja; Trzebicka, Barbara; Dworak, Andrzej; Szweda, Dawid

2016-06-01

In cell or tissue engineering, it is essential to develop a support for cell-to-cell adhesion, which leads to the generation of cell sheets connected by extracellular matrix. Such supports must be hydrophobic and should result in a detachable cell sheet. A thermoresponsive support that enables the cultured cell sheet to detach using only a change in temperature could be an interesting alternative in regenerative medicine. The aim of this study was to evaluate plates covered with thermoresponsive polymers as supports for the formation of fibroblast sheets and to develop a damage-free procedure for cell sheet transfer with the use of membranes as transfer tools. Human skin fibroblasts were seeded on supports coated with a thermoresponsive polymer: commercial UpCell™ dishes (NUNC™) coated with thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) and dishes coated with thermoresponsive poly(tri(ethylene glycol) monoethyl ether methacrylate) (P(TEGMA-EE)). Confluent fibroblast sheets were effectively cultured and harvested from both commercial PNIPAM-coated dishes and laboratory P(TEGMA-EE)-coated dishes. To transfer a detached cell sheet, two membranes, Immobilon-P(®) and SUPRATHEL(®), were examined. The use of SUPRATHEL for relocating the cell sheets opens a new possibility for the clinical treatment of wounds. This study established the background for implementing thermoresponsive supports for transplanting in vitro cultured fibroblasts.

Tocilizumab: therapy and safety management.

PubMed

Pham, Thao; Claudepierre, Pascal; Constantin, Arnaud; de Bandt, Michel; Fautrel, Bruno; Gossec, Laure; Gottenberg, Jacques-Eric; Goupille, Philippe; Guillaume, Séverine; Hachulla, Eric; Masson, Charles; Morel, Jacques; Puéchal, Xavier; Saraux, Alain; Schaeverbeke, Thierry; Wendling, Daniel; Bruckert, Eric; Pol, Stanislas; Mariette, Xavier; Sibilia, Jean

2010-06-01

To develop fact sheets about tocilizumab, in order to assist physicians in the management of patients with inflammatory joint disease. 1. selection by a committee of rheumatology experts of the main topics of interest for which fact sheets were desirable; 2. identification and review of publications relevant to each topic; 3. development of fact sheets based on three levels of evidence: evidence-based medicine, official recommendations, and expert opinion. The 20 experts were rheumatologists and invited specialists in other fields, and they had extensive experience with the management of RA. They were members of the CRI (Club Rhumatismes et Inflammation), a section of the Société Francaise de Rhumatologie. Each fact sheet was revised by several. experts and the overall process was coordinated by three experts. Several topics of major interest were selected: contraindications of tocilizumab; the management of adverse effects and concomitant diseases that may develop during tocilizumab therapy; and the management of everyday situations such as pregnancy, surgery, and immunizations. After a review of the literature and discussions among experts, a consensus was developed about the content of the fact sheets presented here. These fact sheets focus on several points: Several topics of major interest were selected: contraindications of tocilizumab; the management of adverse effects and concomitant diseases that may develop during tocilizumab therapy; and the management of everyday situations such as pregnancy, surgery, and immunizations. After a review of the literature and discussions among experts, a consensus was developed about the content of the fact sheets presented here. These fact sheets focus on several points: 1. in RA, initiation and monitoring of tocilizumab therapy, management of patients with specific past histories, and specific clinical situations such as pregnancy; 2. diseases other than RA, such as juvenile idiopathic arthritis; 3. models of letters for informing the rheumatologist and general practitioner; 4. and patient information. These tocilizumab fact sheets built on evidence-based medicine and expert opinion will serve as a practical tool for assisting physicians who manage patients on tocilizumab therapy. They will be available continuously at www.cri-net.com and updated at appropriate intervals. Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

Crew Launch Vehicle (CLV) Upper Stage Configuration Selection Process

NASA Technical Reports Server (NTRS)

Davis, Daniel J.; Coook, Jerry R.

2006-01-01

The Crew Launch Vehicle (CLV), a key component of NASA's blueprint for the next generation of spacecraft to take humans back to the moon, is being designed and built by engineers at NASA s Marshall Space Flight Center (MSFC). The vehicle s design is based on the results of NASA's 2005 Exploration Systems Architecture Study (ESAS), which called for development of a crew-launch system to reduce the gap between Shuttle retirement and Crew Exploration Vehicle (CEV) Initial Operating Capability, identification of key technologies required to enable and significantly enhance these reference exploration systems, and a reprioritization of near- and far-term technology investments. The Upper Stage Element (USE) of the CLV is a clean-sheet approach that is being designed and developed in-house, with element management at MSFC. The USE concept is a self-supporting cylindrical structure, approximately 115' long and 216" in diameter, consisting of the following subsystems: Primary Structures (LOX Tank, LH2 Tank, Intertank, Thrust Structure, Spacecraft Payload Adaptor, Interstage, Forward and Aft Skirts), Secondary Structures (Systems Tunnel), Avionics and Software, Main Propulsion System, Reaction Control System, Thrust Vector Control, Auxiliary Power Unit, and Hydraulic Systems. The ESAS originally recommended a CEV to be launched atop a four-segment Space Shuttle Main Engine (SSME) CLV, utilizing an RS-25 engine-powered upper stage. However, Agency decisions to utilize fewer CLV development steps to lunar missions, reduce the overall risk for the lunar program, and provide a more balanced engine production rate requirement prompted engineers to switch to a five-segment design with a single Saturn-derived J-2X engine. This approach provides for single upper stage engine development for the CLV and an Earth Departure Stage, single Reusable Solid Rocket Booster (RSRB) development for the CLV and a Cargo Launch Vehicle, and single core SSME development. While the RSRB design has changed since the CLV Project's inception, the USE design has remained essentially a clean-sheet approach. Although a clean-sheet upper stage design inherently carries more risk than a modified design, it does offer many advantages: a design for increased reliability; built-in extensibility to allow for commonality/growth without major redesign; and incorporation of state-of-the-art materials, hardware, and design, fabrication, and test techniques and processes to facilitate a potentially better, more reliable system. Because consideration was given in the ESAS to both clean-sheet and modified USE designs, this paper will highlight the advantages and disadvantages of both approaches and provide a detailed discussion of trades/selections made that led to the final upper stage configuration.

Experimental investigation of a 1 kA/cm{sup 2} sheet beam plasma cathode electron gun

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, Niraj, E-mail: niraj.ceeri@gmail.com; Narayan Pal, Udit; Prajesh, Rahul

In this paper, a cold cathode based sheet-beam plasma cathode electron gun is reported with achieved sheet-beam current density ∼1 kA/cm{sup 2} from pseudospark based argon plasma for pulse length of ∼200 ns in a single shot experiment. For the qualitative assessment of the sheet-beam, an arrangement of three isolated metallic-sheets is proposed. The actual shape and size of the sheet-electron-beam are obtained through a non-conventional method by proposing a dielectric charging technique and scanning electron microscope based imaging. As distinct from the earlier developed sheet beam sources, the generated sheet-beam has been propagated more than 190 mm distance inmore » a drift space region maintaining sheet structure without assistance of any external magnetic field.« less

2D sandwich-like sheets of iron oxide grown on graphene as high energy anode material for supercapacitors.

PubMed

Qu, Qunting; Yang, Shubin; Feng, Xinliang

2011-12-08

2D sandwich-like sheets of iron oxide grown on graphene as high energy anode material for supercapacitors are prepared from the direct growth of FeOOH nanorods on the surface of graphene and the subsequent electrochemical transformation of FeOOH to Fe(3)O(4). The Fe(3)O(4) @RGO nanocomposites exhibit superior capacitance (326 F g(-1)), high energy density (85 Wh kg(-1)), large power, and good cycling performance in 1 mol L(-1) LiOH solution. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Dynamic Harris current sheet thickness from Cluster current density and plasma measurements

NASA Technical Reports Server (NTRS)

Thompson, S. M.; Kivelson, M. G.; Khurana, K. K.; McPherron, R. L.; Weygand, J. M.; Balogh, A.; Reme, H.; Kistler, L. M.

2005-01-01

We use the first accurate measurements of current densities in the plasma sheet to calculate the half-thickness and position of the current sheet as a function of time. Our technique assumes a Harris current sheet model, which is parameterized by lobe magnetic field B(o), current sheet half-thickness h, and current sheet position z(sub o). Cluster measurements of magnetic field, current density, and plasma pressure are used to infer the three parameters as a function of time. We find that most long timescale (6-12 hours) current sheet crossings observed by Cluster cannot be described by a static Harris current sheet with a single set of parameters B(sub o), h, and z(sub o). Noting the presence of high-frequency fluctuations that appear to be superimposed on lower frequency variations, we average over running 6-min intervals and use the smoothed data to infer the parameters h(t) and z(sub o)(t), constrained by the pressure balance lobe magnetic field B(sub o)(t). Whereas this approach has been used in previous studies, the spatial gnuhen& now provided by the Cluster magnetometers were unavailable or not well constrained in earlier studies. We place the calculated hdf&cknessa in a magnetospheric context by examining the change in thickness with substorm phase for three case study events and 21 events in a superposed epoch analysis. We find that the inferred half-thickness in many cases reflects the nominal changes experienced by the plasma sheet during substorms (i.e., thinning during growth phase, thickening following substorm onset). We conclude with an analysis of the relative contribution of (Delta)B(sub z)/(Delta)X to the cross-tail current density during substorms. We find that (Delta)B(sub z)/(Delta)X can contribute a significant portion of the cross-tail c m n t around substorm onset.

Subcritical crack growth in fibrous materials

NASA Astrophysics Data System (ADS)

Santucci, S.; Cortet, P.-P.; Deschanel, S.; Vanel, L.; Ciliberto, S.

2006-05-01

We present experiments on the slow growth of a single crack in a fax paper sheet submitted to a constant force F. We find that statistically averaged crack growth curves can be described by only two parameters: the mean rupture time τ and a characteristic growth length ζ. We propose a model based on a thermally activated rupture process that takes into account the microstructure of cellulose fibers. The model is able to reproduce the shape of the growth curve, the dependence of ζ on F as well as the effect of temperature on the rupture time τ. We find that the length scale at which rupture occurs in this model is consistently close to the diameter of cellulose microfibrils.

Chemical vapor deposition growth

NASA Technical Reports Server (NTRS)

Ruth, R. P.; Manasevit, H. M.; Johnson, R. E.; Kenty, J. L.; Moudy, L. A.; Simpson, W. I.; Yang, J. J.

1976-01-01

A laboratory type CVD reactor system with a vertical deposition chamber and sample pedestal heated by an external RF coil has been extensively modified by installation of mass flow controllers, automatic process sequence timers, and special bellows-sealed air-operated valves for overall improved performance. Various film characterization procedures, including classical metallography, SEM analyses, X ray diffraction analyses, surface profilometry, and electrical measurements (resistivity, carrier concentration, mobility, spreading resistance profiles, and minority-carrier lifetime by the C-V-t method) area used to correlate Si sheet properties with CVD parameters and substrate properties. Evaluation procedures and measurements are given. Experimental solar cell structures were made both in epitaxial Si sheet (on sapphire substrates) and in polycrystalline material on alumina substrates, the former to provide an indication of what might be an upper limit on performance of the latter. Preliminary results are given, as obtained in cell structures not specially designed to allow for the unique properties of the sheet material, and fabricated in material known to be far from optimum for photovoltaic performance. Low power conversion efficiencies have been obtained in the epitaxial as well as the polycrystalline Si sheet.

Fe doped TiO2 nanofibers on the surface of graphene sheets for photovoltaics applications

NASA Astrophysics Data System (ADS)

Farhangi, Nasrin; Medina-Gonzalez, Yaocihuatl; Charpentier, Paul A.

2011-08-01

Highly ordered, visible light driven TiO2 nanowire arrays doped with Fe photocatalysts were grown on the surface of functionalized graphene sheets (FGSs) using a sol-gel method with titanium isopropoxide (TIP) monomer, acetic acid (HAc) as the polycondensation agent and iron chloride in the green solvent, supercritical carbon dioxide (scCO2). The morphology of the synthesized materials was studied by SEM and TEM, which showed uniform formation of Fe doped TiO2 nanofibers on the surface of graphene sheets, which acted as a template for nanowire growth through surface -COOH functionalities. Increasing Fe content in the nanowires did not change the morphology significantly. Optical properties of the synthesized composites were examined by UV spectroscopy which showed a significant reduction in band gap with increasing Fe content, i.e. 2.25 eV at 0.6% Fe. The enhancement of the optical properties of synthesized materials was confirmed by photocurrent measurement. The optimum sample containing 0.6% Fe doped TiO2 on the graphene sheets increased the power conversation efficiency by 6-fold in comparison to TiO2 alone.

Onset of fast "ideal" tearing in thin current sheets: Dependence on the equilibrium current profile

NASA Astrophysics Data System (ADS)

Pucci, F.; Velli, M.; Tenerani, A.; Del Sarto, D.

2018-03-01

In this paper, we study the scaling relations for the triggering of the fast, or "ideal," tearing instability starting from equilibrium configurations relevant to astrophysical as well as laboratory plasmas that differ from the simple Harris current sheet configuration. We present the linear tearing instability analysis for equilibrium magnetic fields which (a) go to zero at the boundary of the domain and (b) contain a double current sheet system (the latter previously studied as a Cartesian proxy for the m = 1 kink mode in cylindrical plasmas). More generally, we discuss the critical aspect ratio scalings at which the growth rates become independent of the Lundquist number S, in terms of the dependence of the Δ' parameter on the wavenumber k of unstable modes. The scaling Δ'(k) with k at small k is found to categorize different equilibria broadly: the critical aspect ratios may be even smaller than L/a ˜ Sα with α = 1/3 originally found for the Harris current sheet, but there exists a general lower bound α ≥ 1/4.

Perforating Thin Metal Sheets

NASA Technical Reports Server (NTRS)

Davidson, M. E.

1985-01-01

Sheets only few mils thick bonded together, punched, then debonded. Three-step process yields perforated sheets of metal. (1): Individual sheets bonded together to form laminate. (2): laminate perforated in desired geometric pattern. (3): After baking, laminate separates into individual sheets. Developed for fabricating conductive layer on blankets that collect and remove ions; however, perforated foils have other applications - as conductive surfaces on insulating materials; stiffeners and conductors in plastic laminates; reflectors in antenna dishes; supports for thermal blankets; lightweight grille cover materials; and material for mockup of components.

Change in oligosaccharides during processing of soybean sheet.

PubMed

Wang, Qiushuang; Ke, Leqin; Yang, Dongmei; Bao, Bili; Jiang, Jianmei; Ying, Tiejin

2007-01-01

Oligosaccharides have been credited with many health-promoting functions, which had been identified in many clinical studies, such as promoting the growth of Bifidobacterium in human intestine and balance of intestinal bacteria, modulating the immune response, inhibition of cancer and tumor, stimulation of mineral absorption. In this study the effect of processing unit operations on the levels of soybean oligosaccharides during production of soybean sheet were investigated. The concentrations of oligosaccharide in initial raw soybean were: sucrose 43.05 g/kg, raffinose 7.52 g/kg and stachyose 41.32 g/kg (in dry matter). Oligosaccharide losses in the soaking water, in the first filtrating stage, in the second filtrating stage and finally in the sheet formation stage were 0.68, 10.3, 8.15 and 47.22 g/kg (initial dry soybean) respectively, representing 0.74, 11.21, 8.87 and 51.39% of the total oligosaccharides present in the initial soybeans. The recovery of oligosaccharides in the final soybean sheet from the initial soybean was 27.92%. The loss of soybean oligosaccharides in different processing stages, especially in the by-product, the sweet slurry, was considerable. The loss of oligosaccharides was mainly associated with water/matter removal in production process. The analysis of loss profile implied possible ways to improve the technology for production of oligosaccharides-enriched soy-sheets.

Some tradeoffs in ingot shaping and price of solar photovoltaic modules

NASA Technical Reports Server (NTRS)

Daud, T.

1982-01-01

Growth of round ingots is cost-effective for sheets but leaves unused space when round cells are packed into a module. This reduces the packing efficiency, which approaches 95% for square cells, to about 78% and reduces the conversion efficiency of the module by the same ratio. Shaping these ingots into squares with regrowth of cut silicon improves the packing factor, but increases growth cost. The cost impact on solar cell modules was determined by considering shaping ingots in stages from full round to complete square. The sequence of module production with relevant price allocation guidelines is outlined. The severe penalties in add-on price due to increasing slice thickness and kerf are presented. Trade-offs between advantages of recycling silicon and shaping costs are developed for different slicing scenarios. It is shown that shaping results in cost saving of up to 21% for a 15 cm dia. ingot.

Theory for substorms triggered by sudden reductions in convection

NASA Technical Reports Server (NTRS)

Lyons, L. R.

1996-01-01

Many substorm expansions are triggered by interplanetary magnetic field changes that reduce magnetospheric convection. This suggests that expansion onsets are a result of a reduction in the large-scale electric field imparted to the magnetosphere from the solar wind. Such a reduction disrupts the inward motion and energization of plasma sheet particles that occur during the growth phase. It is proposed that the resulting magnetic drift of particles and a large dawn to dusk gradient in the ion energies leads to a longitudinally localized reduction in the plasma pressure, and thus, to the current wedge formation. This theory accounts for the rapid development of the expansion phase relative to growth phase, the magnitude of the wedge currents, the speeds of tailward and westward expansion of the current reduction region in the equatorial plane, and the speeds of the poleward and westward motion of active aurora in the ionosphere.

Morphological properties of tunnel valleys of the southern sector of the Laurentide Ice Sheet and implications for their formation

NASA Astrophysics Data System (ADS)

Livingstone, Stephen J.; Clark, Chris D.

2016-07-01

Tunnel valleys have been widely reported on the bed of former ice sheets and are considered an important expression of subglacial meltwater drainage. Although known to have been cut by erosive meltwater flow, the water source and development of channels has been widely debated; ranging between outburst flood events through to gradually occurring channel propagation. We have mapped and analysed the spatial pattern and morphometry of tunnel valleys and associated glacial landforms along the southern sector of the former Laurentide Ice Sheet from high-resolution digital elevation models. Around 2000 tunnel valleys have been mapped, revealing an organised pattern of sub-parallel, semi-regularly spaced valleys that form in distinctive clusters. The tunnel valleys are typically < 20 km long, and 0.5-3 km wide, although their width varies considerably down-valley. They preferentially terminate at moraines, which suggests that formation is time dependent; while we also observe some tunnel valleys that have grown headwards out of hill-hole pairs. Analysis of cross-cutting relationships between tunnel valleys, moraines and outwash fans permits reconstruction of channel development in relation to the retreating ice margin. This palaeo-drainage reconstruction demonstrates incremental growth of most valleys, with some used repeatedly or for long periods, during deglaciation, while others were abandoned shortly after their formation. Our data and interpretation support gradual (rather than a single-event) formation of most tunnel valleys with secondary contributions from flood drainage of subglacial and or supraglacially stored water down individual tunnel valleys. The distribution and morphology of tunnel valleys is shown to be sensitive to regional factors such as basal thermal regime, ice and bed topography, timing and climate.

The evolution of the Dogger Bank, North Sea: A complex history of terrestrial, glacial and marine environmental change

NASA Astrophysics Data System (ADS)

Cotterill, Carol J.; Phillips, Emrys; James, Leo; Forsberg, Carl Fredrik; Tjelta, Tor Inge; Carter, Gareth; Dove, Dayton

2017-09-01

This paper presents a summary of the results of a detailed multidisciplinary study of the near surface geology of the Dogger Bank in the southern central North Sea, forming part of a site investigation for a major windfarm development undertaken by the Forewind consortium. It has revealed that the Dogger Bank is internally complex rather than comprising a simple ;layer cake; of the Quaternary sediments as previously thought. Regional and high-resolution seismic surveys have enabled a revised stratigraphic framework to be established for the upper part of this sequence which comprises the Eem (oldest), Dogger Bank, Bolders Bank formations and Botney Cut Formation (youngest), overlain by a typically thin Holocene sequence. Detailed mapping of key horizons identified on the high-resolution seismic profiles has led to the recognition of a series of buried palaeo-landsystems which are characterised by a range of features including; glacial, glacifluvial and fluvial channels, a large-scale glacitectonic thrust-moraine complex with intervening ice-marginal basins, a lacustrine basin and marine ravinement surfaces. Interpretation of these buried landscapes has enabled the development of an environmental change model to explain the evolution of the Dogger Bank. This evolution was driven by the complex interplay between climate change, ice sheet dynamics and sea level change associated with the growth and subsequent demise of the British and Irish and Fennoscandian ice sheets during the Weichselian glaciation. Following the decay of these ice sheets the Dogger Bank entered a period of significant climatic and environmental flux which saw a terrestrial landscape being progressively inundated as sea levels rose during the Holocene.

Automated knot detection with visual post-processing of Douglas-fir veneer images

Treesearch

C.L. Todoroki; Eini C. Lowell; Dennis Dykstra

2010-01-01

Knots on digital images of 51 full veneer sheets, obtained from nine peeler blocks crosscut from two 35-foot (10.7 m) long logs and one 18-foot (5.5 m) log from a single Douglas-fir tree, were detected using a two-phase algorithm. The algorithm was developed using one image, the Development Sheet, refined on five other images, the Training Sheets, and then applied to...

Development of improved low-strain creep strength in Cabot alloy R-41 sheet. [nickel base sheet alloy for reentry shielding

NASA Technical Reports Server (NTRS)

Rothman, M. F.

1984-01-01

The feasibility of improving the low-strain creep properties of a thin gauge nickel base sheet alloy through modified heat treatment or through development of a preferred crystal-lographic texture was investigated. The basic approach taken to improve the creep strength of the material by heat treatment was to increase grain size by raising the solution treatment temperature for the alloy to the range of 1420 K to 1475 K (2100 F to 2200 F). The key technical issue involved was maintenance of adequate tensile ductility following the solutioning of M6C primary carbides during the higher temperature solution treatment. The approach to improve creep properties by developing a sheet texture involved varying both annealing temperatures and the amount of prior cold work. Results identified a heat treatment for alloy R-14 sheet which yields a substantial creep-life advantage at temperatures above 1090 K (1500 F) when compared with material given the standard heat treatment. At the same time, this treatment provides reasonable tensile ductility over the entire temperature range of interest. The mechanical properties of the material given the new heat treatment are compared with those for material given the standard heat treatment. Attempts to improve creep strength by developing a sheet texture were unsuccessful.

Microenvironment Induced Spheroid to Sheeting Transition of Immortalized Human Keratinocytes (HaCaT) Cultured in Microbubbles Formed in Polydimethylsiloxane

PubMed Central

Chandrasekaran, Siddarth; Giang, Ut-Binh; King, Michael R.; DeLouise, Lisa A

2011-01-01

The in vivo cellular microenvironment is regulated by a complex interplay of soluble factors and signaling molecules secreted by cells and it plays a critical role in the growth and development of normal and diseased tissues. In vitro systems that can recapitulate the microenvironment at the cellular level are needed to investigate the influence of autocrine signaling and extracellular matrix effects on tissue homeostasis, regeneration, and disease development and progression. In this study we report the use of microbubble technology as a means to culture cells in a controlled microenvironment in which cells can influence their function through autocrine signaling. Microbubbles (MB) are small spherical cavities about 100–300 µm in diameter formed in hydrophobic polymer polydimethylsiloxane (PDMS) with ~60–100 µm circular openings and aspect ratio ~3.5. We demonstrate that the unique architecture of the microbubble compartment is advantaged for cell culture using HaCaT cells, an immortalized keratinocyte cell line. We observe that HaCaT cells, seeded in microbubbles (15–20 cells / MB) and cultured under standard conditions, adopt a compact 3-D spheroidal morphology. Within 2–3 days, the cells transition to a sheeting morphology. Through experimentation and simulation we show that this transition in morphology is due to the unique architecture of the microbubble compartment which enables cells to condition their local microenvironment. The small media volume per cell and the development of shallow concentration gradients allow factors secreted by the cells to rise to bioactive levels. The kinetics of the morphology transition depends on the number of cells seeded per microbubble; higher cell seeding induces a more rapid transition. HaCaT cells seeded onto PDMS cured in 96-well plates also form compact spheroids but they do not transition to a sheeting morphology even after several weeks of culture. The importance of soluble factor accumulation in driving this morphology transition in microbubbles is supported by the observation that spheroids do not form when cells - seeded into microbubbles or onto PDMS cured in 96 well plates - are cultured in media conditioned by HaCaT cells grown in standard tissue culture plate. We observed that the addition of TGF-β1 to the growth media induced cells to proliferate in a sheeting morphology from the onset both on PDMS cured in 96-well plates and in microbubbles. TGF-β1 is a morphogen known to regulate epithelial-to-mesenchymal transition (EMT). Studies of the role of Ca2+ concentration and changes in Ecadherin expression additionally support an EMT-like HaCaT morphology transition. These findings taken together validate the microbubble compartment as a unique cell culture platform that can potentially transform investigative studies in cell biology and in particular the tumor microenvironment. Targeting the tumor microenvironment is an emerging area of anti-cancer therapy. PMID:21724250

Development and evaluation of adsorption sheet (HD safe sheet-U) using active carbon for the purpose of the preventing the contamination diffusion of urinary excreted anticancer drug.

PubMed

Sato, Junya; Ohkubo, Haruka; Sasaki, Yuki; Yokoi, Makoto; Hotta, Yasunori; Kudo, Kenzo

2017-01-01

Certain amount of anticancer drugs is excreted in the urine of patients receiving anticancer drugs, and urinary scattering including anticancer drugs at excretion has become a route of anticancer drug contamination. Therefore, we developed an active carbon sheet (HD safe sheet-U) that prevented diffusion by adsorbing anticancer drugs including that excreted in urine. The present study conducted a performance evaluation of this sheet. The adsorption performance of active carbon to anticancer drug in the urine was evaluated by determining concentration changes in the active carbon suspension (5 mg/mL) of 14 kinds of anticancer drugs (cyclophosphamide, ifosfamide, carboplatin, cisplatin, methotrexate, 5-fluorouracil, cytarabine, gemcitabine, doxorubicin, epirubicin, paclitaxel, docetaxel, etoposide, and irinotecan) diluted with artificial urine. Adhesion of the anticancer drug dropping on the sheet to a slipper sole was evaluated because urine including anticancer drugs is scattered on the floor, which can spread by adhering to shoe soles of patients and healthcare workers. The performance of the active carbon sheet was compared with two other types of medical adsorption sheets used as control sheets. Anticancer drugs diluted with artificial urine (1 mL) were dropped on the active carbon sheet and the two control sheets. The sheets were trod with slippers made by polyvinyl chloride. The adhered anticancer drug was wiped off and its quantity was determined. A remarkable decrease in anticancer drug concentrations, except for cisplatin, was detected by mixture of active carbon in the artificial urine (0-79.6%). The quantity of anticancer drug adhesion to slipper soles from the active carbon sheet was significantly lower compared with that observed for the two control sheets for eight kinds of anticancer drugs (cyclophosphamide, ifosfamide, carboplatin, methotrexate, cytarabine, gemcitabine, doxorubicin, and docetaxel). There was no adhesion in cyclophosphamide and docetaxel. Furthermore, the quantities of adhesion in cytarabine, gemcitabine, doxorubicin, paclitaxel, and irinotecan were lower than determination limit. Active carbon might be effective in adsorbing urinary anticancer drugs. The active carbon sheet adsorbed urinary excreted anticancer drugs, and use of such sheets might prevent diffusion of contamination due to urinary excreted anticancer drugs.

From cyclic ice streaming to Heinrich-like events: the grow-and-surge instability in the Parallel Ice Sheet Model

NASA Astrophysics Data System (ADS)

Feldmann, Johannes; Levermann, Anders

2017-08-01

Here we report on a cyclic, physical ice-discharge instability in the Parallel Ice Sheet Model, simulating the flow of a three-dimensional, inherently buttressed ice-sheet-shelf system which periodically surges on a millennial timescale. The thermomechanically coupled model on 1 km horizontal resolution includes an enthalpy-based formulation of the thermodynamics, a nonlinear stress-balance-based sliding law and a very simple subglacial hydrology. The simulated unforced surging is characterized by rapid ice streaming through a bed trough, resulting in abrupt discharge of ice across the grounding line which is eventually calved into the ocean. We visualize the central feedbacks that dominate the subsequent phases of ice buildup, surge and stabilization which emerge from the interaction between ice dynamics, thermodynamics and the subglacial till layer. Results from the variation of surface mass balance and basal roughness suggest that ice sheets of medium thickness may be more susceptible to surging than relatively thin or thick ones for which the surge feedback loop is damped. We also investigate the influence of different basal sliding laws (ranging from purely plastic to nonlinear to linear) on possible surging. The presented mechanisms underlying our simulations of self-maintained, periodic ice growth and destabilization may play a role in large-scale ice-sheet surging, such as the surging of the Laurentide Ice Sheet, which is associated with Heinrich events, and ice-stream shutdown and reactivation, such as observed in the Siple Coast region of West Antarctica.

Conducting Layered Organic-inorganic Halides Containing <110>-Oriented Perovskite Sheets.

PubMed

Mitzi, D B; Wang, S; Feild, C A; Chess, C A; Guloy, A M

1995-03-10

Single crystals of the layered organic-inorganic perovskites, [NH(2)C(I=NH(2)](2)(CH(3)NH(3))m SnmI3m+2, were prepared by an aqueous solution growth technique. In contrast to the recently discovered family, (C(4)H(9)NH(3))(2)(CH(3)NH(3))n-1SnnI3n+1, which consists of (100)-terminated perovskite layers, structure determination reveals an unusual structural class with sets of m <110>-oriented CH(3)NH(3)SnI(3) perovskite sheets separated by iodoformamidinium cations. Whereas the m = 2 compound is semiconducting with a band gap of 0.33 +/- 0.05 electron volt, increasing m leads to more metallic character. The ability to control perovskite sheet orientation through the choice of organic cation demonstrates the flexibility provided by organic-inorganic perovskites and adds an important handle for tailoring and understanding lower dimensional transport in layered perovskites.

Solid state welding processes for an oxide dispersion strengthened nickel-chromium-aluminum alloy

NASA Technical Reports Server (NTRS)

Moore, T. J.

1975-01-01

Solid-state welding processes were evaluated for joining TD-NiCrAl (Ni-16Cr-4Al-2ThO2) alloy sheet. Both hot-press and resistance spot welding techniques were successfully applied in terms of achieving grain growth across the bond line. Less success was achieved with a resistance seam welding process. In stress-rupture shear and tensile shear tests of lap joints at 1100 C, most failures occurred in the parent material, which indicates that the weld quality was good and that the welds were not a plane of weakness. The overall weld quality was not as good as previously attained with TD-NiCr, probably because the presence of alumina at the faying surfaces and the developmental TD-NiCrAl sheet, which was not of the quality of the TD-NiCr sheet in terms of surface flatness and dimensional control.

PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

NASA Astrophysics Data System (ADS)

Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

2016-09-01

This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

Crack-tip-opening angle measurements and crack tunneling under stable tearing in thin sheet 2024-T3 aluminum alloy

NASA Technical Reports Server (NTRS)

Dawicke, D. S.; Sutton, M. A.

1993-01-01

The stable tearing behavior of thin sheets 2024-T3 aluminum alloy was studied for middle crack tension specimens having initial cracks that were: flat cracks (low fatigue stress) and 45 degrees through-thickness slant cracks (high fatigue stress). The critical crack-tip-opening angle (CTOA) values during stable tearing were measured by two independent methods, optical microscopy and digital image correlation. Results from the two methods agreed well. The CTOA measurements and observations of the fracture surfaces showed that the initial stable tearing behavior of low and high fatigue stress tests is significantly different. The cracks in the low fatigue stress tests underwent a transition from flat-to-slant crack growth, during which the CTOA values were high and significant crack tunneling occurred. After crack growth equal to about the thickness, CTOA reached a constant value of 6 deg and after crack growth equal to about twice the thickness, crack tunneling stabilized. The initial high CTOA values, in the low fatigue crack tests, coincided with large three-dimensional crack front shape changes due to a variation in the through-thickness crack tip constraint. The cracks in the high fatigue stress tests reach the same constant CTOA value after crack growth equal to about the thickness, but produced only a slightly higher CTOA value during initial crack growth. For crack growth on the 45 degree slant, the crack front and local field variables are still highly three-dimensional. However, the constant CTOA values and stable crack front shape may allow the process to be approximated with two-dimensional models.

A panel method study of vortex sheets with special emphasis on sheets of axisymmetric geometry. M.S. Thesis

NASA Technical Reports Server (NTRS)

Sugioka, I.; Widnall, S. E.

1985-01-01

The self induced evolution of a vortex sheet was simulated by modeling the sheet using an integration of discrete elements of vorticity. Replacing small sections of a vortex sheet by flat panels of constant vorticity is found to reproduce more accurately the initial conditions for the Lagrangian simulation technique than replacement by point vortices. The flat panel method for the vortex sheet was then extended to model axisymmetric vortex sheets. The local and far field velocities induced by the axisymmetric panels were obtained using matched asymptotic analysis, and some of the uncertainties involved in other models of the axisymmetric vortex sheet have been eliminated. One important result of this analysis is the determination of the proper choice of core size for a circular vortex filament which may replace a section of an axisymmetric vortex sheet. Roll-up of both two dimensional and axisymmetric vortex sheets was computed using the panel methods developed in the report.

Does Antarctic Glaciation Cause an Intensification of the Indo-Asian Monsoon Near the Eocene-Oligocene Transition?

NASA Astrophysics Data System (ADS)

Goldner, A. P.; Huber, M.; Caballero, R.

2011-12-01

High latitude ice volume changes has been suggested to have profound effects on the position of the Intertropical Convergence Zone (ITCZ). Here we simulate the atmospheric impacts that an Antarctica ice sheet of modern size has on the hydrologic cycle and atmospheric circulation using the community earth system model (CESM1.0) from the National Center for Atmospheric Research (NCAR) in Eocene simulations. Results show that the placement of an ice sheet in Antarctica in a late Eocene climate simulation cools the planet around ~2 Kelvin and causes a poleward displacement of the ITCZ in both hemispheres. Because the ITCZ is linked to the global monsoonal circulation. The shift results in an intensification of precipitation over prominent monsoon regions like Asia, Africa, and Australia. Aridification occurs in central Asia and western North America in agreement with many of the proxy records for the Eocene-Oligocene transition. The shift in atmospheric circulation and precipitation anomalies are robust in further sensitivity studies where we remove the ice sheet, but keep topography high over Antarctica and under different CO2 levels (560 and 1120 ppmv). We hypothesize that the height of the initial ice growth on Antarctica could be a significant factor in shifting the hydrologic cycle and matching proxy records over important regions like the Indo-Asian Monsoon region during the Eocene-Oligocene transition. These modeling results show that other factors besides declining atmospheric CO2, changes in orbital cycles, and the height of the Tibetan Plateau can have significant impacts on the tropical circulation and the global hydrologic cycle, especially the Indo-Asian Monsoon in past climate periods where significant changes in ice sheet growth occurred.

Stress evolution of GaN/AlN heterostructure grown on 6H-SiC substrate by plasma assisted molecular beam epitaxy

NASA Astrophysics Data System (ADS)

Agrawal, M.; Ravikiran, L.; Dharmarasu, N.; Radhakrishnan, K.; Karthikeyan, G. S.; Zheng, Y.

2017-01-01

The stress evolution of GaN/AlN heterostructure grown on 6H-SiC substrate by plasma assisted molecular beam epitaxy (PA-MBE) has been studied. AlN nucleation layer and GaN layer were grown as a function of III/V ratio. GaN/AlN structure is found to form buried cracks when AlN is grown in the intermediate growth regime(III/V˜1)and GaN is grown under N-rich growth regime (III/V<1). The III/V ratio determines the growth mode of the layers that influences the lattice mismatch at the GaN/AlN interface. The lattice mismatch induced interfacial stress at the GaN/AlN interface relaxes by the formation of buried cracks in the structure. Additionally, the stress also relaxes by misorienting the AlN resulting in two misorientations with different tilts. Crack-free layers were obtained when AlN and GaN were grown in the N-rich growth regime (III/V<1) and metal rich growth regime (III/V≥1), respectively. AlGaN/GaN high electron mobility transistor (HEMT) heterostructure was demonstrated on 2-inch SiC that showed good two dimensional electron gas (2DEG) properties with a sheet resistance of 480 Ω/sq, mobility of 1280 cm2/V.s and sheet carrier density of 1×1013 cm-2.

3D modelling of the Tejeda Caldera cone-sheet swarm, Gran Canaria, Canary Islands, Spain

NASA Astrophysics Data System (ADS)

Samrock, Lisa K.; Jensen, Max J.; Burchardt, Steffi; Troll, Valentin R.; Mattsson, Tobias; Geiger, Harri

2015-04-01

Cone-sheet swarms provide vital information on the interior of volcanic systems and their plumbing systems (e.g. Burchardt et al. 2013). This information is important for the interpretation of processes and dynamics of modern and ancient volcanic systems, and is therefore vital for assessing volcanic hazards and to reduce risks to modern society. To more realistically model cone-sheet emplacement an approximation of their 3D shape needs to be known. Most cone-sheet swarms are not sufficiently exposed laterally and/or vertically, however, which makes it difficult to determine the geometry of a cone-sheet swarm at depth, especially since different shapes (e.g. convex, straight or concave continuations) would produce a similar trace at the surface (cf. Burchardt et al. 2011, and references therein). The Miocene Tejeda Caldera on Gran Canaria, Canary Islands, Spain, hosts a cone-sheet swarm that was emplaced into volcaniclastic caldera infill at about 12.3-7.3 Ma (Schirnick et al. 1999). The dyke swarm displays over 1000 m of vertical exposure and more than 15 km of horizontal exposure, making it a superb locality to study the evolution of cone-sheet swarms in detail and to determine its actual geometry in 3D space. We have used structural data of Schirnick (1996) to model the geometry of the Tejeda cone-sheet in 3D, using the software Move® by Midland Valley Ltd. Based on previous 2D projections, Schirnick et al. (1999) suggested that the cone-sheet swarm is formed by a stack of parallel intrusive sheets which have a truncated dome geometry and form a concentric structure around a central axis, assuming straight sheet-intrusions. Our 3D model gives insight into the symmetries of the sheets and the overall geometry of the cone-sheet swarm below the surface. This visualization now allows to grasp the complexity of the Tejeda cone-sheet swarm at depth, particularly in relation to different possible cone-sheet geometries suggested in the literature (cf. Burchardt et al. 2011, and references therein), and we discuss the implications of this architecture for the feeding system of the Tejeda volcano and the associated temporal variations of cone-sheet emplacement. References: Burchardt, S., Tanner, D.C., Troll, V.R., Krumbholz, M., Gustafsson, L.E. (2011) Three-dimensional geometry of concentric intrusive sheet swarms in the Geitafell and the Dyrfjöll volcanoes, eastern Iceland. Geochemistry, Geophysics, Geosystems 12(7): Q0AB09. Burchardt, S., Troll, V.R., Mathieu, L., Emeleus, H.C., Donaldson, C.H. (2013) Ardnamruchan 3D cone-sheet architecture explained by a single elongate magma chamber. Scientific Reports 3:2891. Schirnick, C. (1996) Formation of an intracaldera cone sheet dike swarm (Tejeda Caldera, Gran Canaria) (Dissertation). Christian-Albrechts-Universität, Kiel, Germany. Schirnick, C., van den Bogaard, P., Schmincke, H.-U. (1999) Cone-sheet formation and intrusive growth of an oceanic island - The Miocene Tejeda complex on Gran Canaria (Canary Islands). Geology, 27: 207-210.

Insolation-driven 100 kyr glacial cycles and millennial climate change

NASA Astrophysics Data System (ADS)

Abe-Ouchi, A.; Saito, F.; Kawamura, K.; Raymo, M. E.; Okuno, J.; Takahashi, K.; Blatter, H.

2013-12-01

The waxing and waning of Northern Hemisphere ice sheets over the past one million years is dominated by an approximately 100-kyr periodicity and a sawtooth pattern (gradual growth and fast termination). Milankovitch theory proposes that summer insolation at high northern latitudes drives the glacial cycles, and statistical tests demonstrated that the glacial cycles are indeed linked to eccentricity, obliquity and precession cycles. However, insolation alone cannot explain the strong 100 kyr cycle which presumably arises through internal climatic feedbacks. Prior work with conceptual models, for example, showed that glacial terminations are associated with the build-up of Northern Hemisphere 'excess ice', but the physical mechanisms of 100-kyr cycle at work remain unclear. Here, using comprehensive climate and ice sheet models, we show that the ~100-kyr periodicity is explained by insolation and internal feedback amongst the climate, ice sheet and lithosphere/asthenosphere system (reference). We found that equilibrium states of ice sheets exhibit hysteresis responses to summer insolation, and that the shape and position of the hysteresis loop play a key role in determining the periodicities of glacial cycles. The hysteresis loop of the North American ice sheet is such that, after its inception, the ice sheet mass balance remains mostly positive or neutral through several precession cycles whose amplitude decreases towards an eccentricity minimum. The larger the ice sheet grows and extends towards lower latitudes, the smaller is the insolation required to turn the mass balance to negative. Therefore, once the large ice sheet is established, only a moderate increase in insolation can trigger a negative mass balance, leading to a complete retreat within several thousand years, due to the delayed isostatic rebound. The effect of ocean circulation and millennial scale climate change are not playing the dominant role for determing the 100kyr cycle, but are effective for modifying the speed and geographical pattern of the waxing and waning of the Northern Hemisphere ice sheets and their melt water. (reference of the basic results: Abe-Ouchi et al, 2013, Insolation-driven 100,000 year glacial cycles and hysteresis of ice-sheet volume, Nature, 500, 190-193.)

Development of a low energy micro sheet forming machine

NASA Astrophysics Data System (ADS)

Razali, A. R.; Ann, C. T.; Shariff, H. M.; Kasim, N. I.; Musa, M. A.; Ahmad, A. F.

2017-10-01

It is expected that with the miniaturization of materials being processed, energy consumption is also being `miniaturized' proportionally. The focus of this study was to design a low energy micro-sheet-forming machine for thin sheet metal application and fabricate a low direct current powered micro-sheet-forming machine. A prototype of low energy system for a micro-sheet-forming machine which includes mechanical and electronic elements was developed. The machine was tested for its performance in terms of natural frequency, punching forces, punching speed and capability, energy consumption (single punch and frequency-time based). Based on the experiments, the machine can do 600 stroke per minute and the process is unaffected by the machine's natural frequency. It was also found that sub-Joule of power was required for a single stroke of punching/blanking process. Up to 100micron thick carbon steel shim was successfully tested and punched. It concludes that low power forming machine is feasible to be developed and be used to replace high powered machineries to form micro-products/parts.

Functionalised graphene sheets as effective high dielectric constant fillers

PubMed Central

2011-01-01

A new functionalised graphene sheet (FGS) filled poly(dimethyl)siloxane insulator nanocomposite has been developed with high dielectric constant, making it well suited for applications in flexible electronics. The dielectric permittivity increased tenfold at 10 Hz and 2 wt.% FGS, while preserving low dielectric losses and good mechanical properties. The presence of functional groups on the graphene sheet surface improved the compatibility nanofiller/polymer at the interface, reducing the polarisation process. This study demonstrates that functionalised graphene sheets are ideal nanofillers for the development of new polymer composites with high dielectric constant values. PACS: 78.20.Ci, 72.80.Tm, 62.23.Kn PMID:21867505

Functionalised graphene sheets as effective high dielectric constant fillers

NASA Astrophysics Data System (ADS)

Romasanta, Laura J.; Hernández, Marianella; López-Manchado, Miguel A.; Verdejo, Raquel

2011-08-01

A new functionalised graphene sheet (FGS) filled poly(dimethyl)siloxane insulator nanocomposite has been developed with high dielectric constant, making it well suited for applications in flexible electronics. The dielectric permittivity increased tenfold at 10 Hz and 2 wt.% FGS, while preserving low dielectric losses and good mechanical properties. The presence of functional groups on the graphene sheet surface improved the compatibility nanofiller/polymer at the interface, reducing the polarisation process. This study demonstrates that functionalised graphene sheets are ideal nanofillers for the development of new polymer composites with high dielectric constant values. PACS: 78.20.Ci, 72.80.Tm, 62.23.Kn

CNT Sheet Air Electrode for the Development of Ultra-High Cell Capacity in Lithium-Air Batteries

PubMed Central

Nomura, Akihiro; Ito, Kimihiko; Kubo, Yoshimi

2017-01-01

Lithium-air batteries (LABs) are expected to provide a cell with a much higher capacity than ever attained before, but their prototype cells present a limited areal cell capacity of no more than 10 mAh cm−2, mainly due to the limitation of their air electrodes. Here, we demonstrate the use of flexible carbon nanotube (CNT) sheets as a promising air electrode for developing ultra-high capacity in LAB cells, achieving areal cell capacities of up to 30 mAh cm−2, which is approximately 15 times higher than the capacity of cells with lithium-ion battery (LiB) technology (~2 mAh cm−2). During discharge, the CNT sheet electrode experienced enormous swelling to a thickness of a few millimeters because of the discharge product deposition of lithium peroxide (Li2O2), but the sheet was fully recovered after being fully charged. This behavior results from the CNT sheet characteristics of the flexible and fibrous conductive network and suggests that the CNT sheet is an effective air electrode material for developing a commercially available LAB cell with an ultra-high cell capacity. PMID:28378746

Development of a Brazing Alloy for the Mechanically Alloyed High Temperature Sheet Material INCOLOY Alloy MA 956.

DTIC Science & Technology

1981-09-01

OF A BRAZING ALLOY FOR THE MECHANICALLY ALLOYED HIGH TEMPERATURE SHEET MATERIAL INCOLOY ALLOY MA 956 W. E. Morgan and Dr. P. J. Bridges N. Wiggin...PERIOD COVERED DEVELOPMENT OF A BRAZING ALLOY FOR THE Final Report MECHANICALLY ALLOYED HIGH TEMPERATURE Dec 1978 - March 1981 SHEET MATERIAL INCOLOY...block nomber) High temperature ODS alloys, Braze development, Braze alloys, INCOLOY MA 956, Ni-Cr-Pd, Fe-Cr-Pd, Ni-Cr-Ge, Fe-Cr-Ge, Fe-Cr-B, Fe-Cr-Si

ENVIRONMENTAL INFORMATION MANAGEMENT SYSTEM (EIMS) FACT SHEET

EPA Science Inventory

The purpose of the fact sheet is to provide information about the US EPA Office of Research and Developments Environmental Information Management System. The fact sheet indicates the type of records that are in EIMS, systems that are integrated with EIMS as well as some highligh...

Fluid Dynamic and Stability Analysis of a Thin Liquid Sheet

NASA Technical Reports Server (NTRS)

McMaster, Matthew S.

1992-01-01

Interest in thin sheet flows has recently been renewed due to their potential application in space radiators. Theoretical and experimental studies of the fluid dynamics and stability of thin liquid sheet flows have been carried out in this thesis. A computer program was developed to determine the cross-sectional shape of the edge cylinder given the cross-sectional area of the edge cylinder. A stability analysis was performed on a non-planer liquid sheet. A study was conducted to determine the effects of air resistance on the sheet.

Time development of high-altitude auroral acceleration region plasma, potentials, and field-aligned current systems observed by Cluster during a substorm

NASA Astrophysics Data System (ADS)

Hull, A. J.; Chaston, C. C.; Fillingim, M. O.; Mozer, F.; Frey, H. U.

2013-12-01

The auroral acceleration region is an integral link in the chain of events that transpire during substorms, and the currents, plasma and electric fields undergo significant changes driven by complex dynamical processes deep in the magnetotail. These auroral acceleration processes in turn accelerate and heat the plasma that ultimately leads to some of the most intense global substorm auroral displays. The complex interplay between field-aligned current system formation, the development of parallel electric fields, and resultant changes in the plasma constituents that occur during substorms within or just above the auroral acceleration zone remain unclear. We present Cluster multi-point observations within the high-altitude acceleration region (> 3 Re altitude) at key instances during the development of a substorm. Of particular emphasis is on the time-development of the plasma, potentials and currents that occur therein with the aim of ascertaining high-altitude drivers of substorm active auroral acceleration processes and auroral emission consequences. Preliminary results show that the initial onset is dominated by Alfvenic activity as evidenced by the sudden occurrence of relatively intense, short-spatial scale Alfvenic currents and attendant energy dispersed, counterstreaming electrons poleward of the growth-phase arc. The Alfvenic currents are locally planar structures with characteristic thicknesses on the order of a few tens of kilometers. In subsequent passages by the other spacecraft, the plasma sheet region became hotter and thicker via the injection of new hot, dense plasma of magnetospheric origins poleward of the pre-existing growth phase arc. In association with the heating and/or thickening of the plasma sheet, the currents appeared to broaden to larger scales as Alfven dominated activity gave way to either inverted-V dominated or mixed inverted-V and Alfvenic behavior depending on location. The transition from Alfven dominated to inverted-V dominated current systems was quite rapid, occurring in the span of a few minutes. These results suggest that the Alfvenic activity may be an important precursor and perhaps may be playing an essential role in the development of inverted-V arc systems that form during substorms.

Chronology of paleozoic metamorphism and deformation in the Blue Ridge thrust complex, North Carolina and Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, S.A.; Dallmeyer, R.D.

1997-05-01

The Blue Ridge province in northwestern North Carolina and northeastern Tennessee records a multiphase collisional and accretionary history from the Mesoproterozoic through the Paleozoic. To constrain the tectonothermal evolution in this region, radiometric ages have been determined for 23 regionally metamorphosed amphibolites, granitic gneisses, and pelitic schists and from mylonites along shear zones that bound thrust sheets and within an internal shear zone. The garnet ages from the Pumpkin Patch a thrust sheet (458, 455, and 451 Ma) are similar to those from the structurally overlying Spruce Pine thrust sheet (460, 456, 455, and 450 Ma). Both thrust sheets exhibitmore » similar upper amphibolite-facies conditions. Because of the high closure temperature for garnet, the garnet ages are interpreted to date growth at or near the peak of Taconic metamorphism. Devonian metamorphic ages are recognized in the Spruce Pine thrust sheet, where Sm-Nd and Rb-Sr garnet ages of 386 and 393 Ma and mineral isochron ages of 397 {+-} 14 and 375 {+-} 27 Ma are preserved. Hornblendes record similar {sup 40}Ar/{sup 39}Ar, Sm-Nd, and Rb-Sr ages of 398 to 379 Ma. Devonian {sup 40}Ar/{sup 39}Ar hornblende ages are also recorded in the structurally lower Pumpkin Patch thrust sheet. The Devonian mineral ages are interpreted to date a discrete tectonothermal event, as opposed to uplift and slow cooling from an Ordovician metamorphic event. The Mississippian mylonitization is interpreted to represent thrusting and initial assembly of crystalline sheets associated with the Alleghanian orogeny. The composite thrust stack of the Blue Ridge complex was subsequently thrust northwestward along the Linville Falls fault during middle Alleghanian orogeny (about 300 Ma).« less

Transplantation of Scaffold-Free Cartilage-Like Cell-Sheets Made from Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair: A Preclinical Study.

PubMed

Itokazu, Maki; Wakitani, Shigeyuki; Mera, Hisashi; Tamamura, Yoshihiro; Sato, Yasushi; Takagi, Mutsumi; Nakamura, Hiroaki

2016-10-01

The object of this study was to determine culture conditions that create stable scaffold-free cartilage-like cell-sheets from human bone marrow-derived mesenchymal stem cells (hBMSCs) and to assess their effects after transplantation into osteochondral defects in nude rats. (Experiment 1) The hBMSCs were harvested from 3 males, the proliferative and chondrogenic capacities were assessed at passage 1, and the cells were expanded in 3 different culture conditions: (1) 5% fetal bovine serum (FBS), (2) 10% FBS, and (3) 5% FBS with fibroblast growth factor 2 (FGF-2). The cells were harvested and made chondrogenic pellet culture. The cell proliferation rate, glycosaminoglycan/DNA ratio, and safranin-O staining intensity of pellets cultured condition 3 were higher than those of conditions 1 and 2. (Experiment 2) The hBMSCs were expanded and passaged 3 times under culture condition 3, and fabricate the cell-sheets in chondrogenic medium either with or without FBS. The cell-sheets fabricated with FBS maintained their size with flat edges. (Experiment 3) The cell-sheets were transplanted into osteochondral defects in nude rats. Histological analysis was performed at 2, 4, and 12 weeks after surgery. The osteochondral repair was better after sheet transplantation than in the control group and significantly improved Wakitani score. Immunostaining with human-specific vimentin antibody showed that the transplanted cells became fewer and disappeared at 12 weeks. These results indicate that culture with FGF-2 may help to quickly generate sufficient numbers of cells to create stable and reliable scaffold-free cartilage-like cell-sheets, which contribute to the regeneration of osteochondral defects.

Repair Mechanism of Osteochondral Defect Promoted by Bioengineered Chondrocyte Sheet

PubMed Central

Kamei, Naosuke; Adachi, Nobuo; Hamanishi, Michio; Kamei, Goki; Mahmoud, Elhussein Elbadry; Nakano, Tomohiro; Iwata, Takanori; Yamato, Masayuki; Okano, Teruo; Ochi, Mitsuo

2015-01-01

Cell sheet engineering has developed as a remarkable method for cell transplantation. In the field of cartilage regeneration, several studies previously reported that cartilage defects could be regenerated by transplantation of a chondrocyte sheet using cell sheet engineering. However, it remains unclear how such a thin cell sheet could repair a deep cartilage defect. We, therefore, focused on the mechanism of cartilage repair using cell sheet engineering in this study. Chondrocyte sheets and synovial cell sheets were fabricated using cell sheet engineering, and these allogenic cell sheets were transplanted to cover an osteochondral defect in a rat model. Macroscopic and histological evaluation was performed at 4 and 12 weeks after transplantation. Analysis of the gene expression of each cell sheet and of the regenerated tissue at 1 week after transplantation was performed. In addition, green fluorescent protein (GFP) transgenic rats were used as donors (transplanted chondrocyte sheets) or recipients (osteochondral defect models) to identify the cell origin of regenerated cartilage. Cartilage repair was significantly better in the group implanted with a chondrocyte sheet than in that with a synovial cell sheet. The results of gene expression analysis suggest that the possible factor contributing to cartilage repair might be TGFβ1. Cell tracking experiments using GFP transgenic rats showed that the regenerated cartilage was largely composed of cells derived from the transplanted chondrocyte sheets. PMID:25396711

Cancer and its impact on work among the self-employed: A need to bridge the knowledge gap.

PubMed

Sharp, L; Torp, S; Van Hoof, E; de Boer, A G E M

2017-09-01

Self-employment-the so-called flexible layer of the economy-has gained importance following the 2007-2008 global economic and financial crisis. In Europe, the self-employed now comprise on average 15% of workers [Eurostat, Labour market and Labour force survey (LFS) statistics, 2016]. Around one-third of self-employed people also provide jobs for others [European Commission, Fact Sheet. 2015 Employment and Social Developments in Europe Review: frequently asked questions, 2016]. Moreover, this group of workers adapts quickly to changing circumstances. In the UK, for instance, recent growth in self-employment is considered to have made an important contribution to labour market recovery [Hatfield, Self-employment in Europe. London, Institute of Public Policy Research, 2015]. Across the European Union self-employment is viewed as a key enabler of sustainable economic growth and, reflecting this, the Europe 2020 strategy encourages member states both to promote self-employment and to remove measures that discourage it [Library of the European Parliament, Self-employment and social security. Effects on innovation and economic growth, 2013]. © 2017 John Wiley & Sons Ltd.

Seeking Hidden Glaciations in the Greenhouse World: A New Approach Using Nd Isotopes

NASA Astrophysics Data System (ADS)

Scher, H. D.; Bohaty, S. M.

2009-12-01

Ephemeral polar glaciations during the early Cenozoic and Cretaceous have been proposed to account for excursions to higher benthic foraminiferal δ18O values, variations in foraminiferal Sr/Ca ratios, and high-frequency eustatic sea level changes. This interpretation requires modifying the view of an “ice-free” greenhouse climate and raises new questions about how the climate system operated in a greenhouse state. However, very limited information has been gathered about these glaciations, partly because direct sedimentological evidence for ice sheets is lacking. Based on constraints from δ18O records and sea-level estimates, it appears that these glaciations were associated with the growth of small-to-medium ice sheets (5 to 15 x 106 km3) on Antarctica. If these ice sheets were confined to the Antarctic interior, they may not have left any physical evidence of their existence in proximal marine sediments. Yet, it may be possible to detect these “hidden glaciations” with proxies for continental weathering. Neodymium (Nd) isotopes have the potential to identify hidden glaciations because ancient basement rocks on Antarctica are glacially eroded during ice sheet advances. The accompanying weathering pulses contribute an extremely nonradiogenic fingerprint to the Southern Ocean. Nd isotope records derived from fossil fish teeth from circum-Antarctic sediment cores confirm that the Nd isotopic composition of Southern Ocean water masses shifted regionally toward nonradiogenic ɛNd values during the buildup of ice sheets during the Eocene-Oligocene Transition (EOT). The observed response to glacial weathering is particularly relevant to examining ephemeral glaciations because a strong Nd isotope response accompanies the first δ18O step of the EOT. This step, i.e., the precursor glaciation, most likely reflects ice sheets confined to the interior and coastal mountains of Antarctica, which represents a similar situation to the purported ephemeral glaciations. Detecting short lived weathering pulses associated with ephemeral glaciations requires developing high-resolution, well correlated Nd isotope records at multiple locations and paleodepths to reconstruct Nd isotope changes through time. Broad spatial coverage of Nd isotope records is important for distinguishing between circulation changes and weathering pulses. This approach has the potential to reveal the frequency, timing, and duration of ephemeral glaciations.

AN INTEGRAL EQUATION REPRESENTATION OF WIDE-BAND ELECTROMAGNETIC SCATTERING BY THIN SHEETS

EPA Science Inventory

An efficient, accurate numerical modeling scheme has been developed, based on the integral equation solution to compute electromagnetic (EM) responses of thin sheets over a wide frequency band. The thin-sheet approach is useful for simulating the EM response of a fracture system ...

Sonification of cryoconite landscapes over the Greenland ice sheet

NASA Astrophysics Data System (ADS)

Tedesco, M.

2015-12-01

Sonification is the use of non-speech audio to convey information. In sonification, several elements can be altered, modified or manipulated to change the perception of the sound, and in turn, the perception of the information being transmitted. For example, an increase or decrease in pitch, tempo and amplitude can be used to convey the information but this can also happen by varying other less commonly used components. One of the advantages of using sonification lies in the temporal, spatial, amplitude, and frequency resolution that offer complementary and supplementary possibilities with respect to visualization techniques. Two years ago, the outcomes of the PolarSEEDS project (www.polaseeds.org), consisting of sonification of time series of albedo, melting and surface temperature over the Greenland ice sheet, were presented in this very same session. The work that I will discuss in this presentation builds on the PolarSEEDS experience, focusing on the fascinating microcosm of cryoconite. Cryoconite is a unique and extremely fascinating form of glacial cover consisting of aggregated rock dust, inorganic and detrital organic matter, and active microbial colonies. It can be seen as 'living stones', with this ecosystem containing the only form of life that is sustained on the majestic surface of the Greenland ice sheet. Microbes are, indeed, the catalyst for cryoconite formation and growth. The cryoconite constituents radiate metabolic heat promoting glacier hole development, melt water formation, and decreasing glacier surface albedo. Lower albedos cause a positive feedback that further contributes to glacier ablation. Despite their importance, cryoconite systems are poorly studied and little is known about their evolution. In the talk, I will first present and discuss previous sonification projects whose main focus was on the polar regions; then, I will present new sonifications based on data quantifying the distribution and evolution of cryoconite over the west portion of the Greenland ice sheet. Such dataset includes high-resolution digital photography collected from a helicopter-mounted camera in July 2015. The images have an unprecedented spatial resolution of 6 cm, producing a wide spectrum of information that is translated into sounds and 'sonified' through an ad-hoc developed code.

Equatorward moving arcs and substorm onset

NASA Astrophysics Data System (ADS)

Haerendel, Gerhard

2010-07-01

Key observations of phenomena during the growth phase of a substorm are being reviewed with particular attention to the equatorward motion of the hydrogen and electron arcs. The dynamic role of the electron, the so-called growth phase arc, is analyzed. It is part of a current system of type II that is instrumental in changing the dominantly equatorward convection from the polar cap into a sunward convection along the auroral oval. A quantitative model of the arc and associated current system allows determining the energy required for the flow change. It is suggested that high-β plasma outflow from the central current sheet of the tail creates the current generator. Assessment of the energy supplied in this process proves its sufficiency for driving the arc system. The equatorward motion of the arcs is interpreted as a manifestation of the shrinkage of the near-Earth transition region (NETR) between the dipolar magnetosphere and the highly stretched tail. This shrinkage is caused by returning magnetic flux to the dayside magnetosphere as partial replacement of the flux eroded by frontside reconnection. As the erosion of the NETR is proceeding, more and more magnetic flux is demanded from the central current sheet of the near-Earth tail until highly accelerated plasma outflow causes the current sheet to collapse. Propagation of the collapse along the tail triggers reconnection and initiates the substorm.

Machine learnt bond order potential to investigate the low thermal conductivity of stanene nanostructures

NASA Astrophysics Data System (ADS)

Cherukara, Mathew; Narayanan, Badri; Kinaci, Alper; Sasikumar, Kiran; Gray, Stephen; Chan, Maria; Sankaranarayanan, Subramanian

The growth of stanene on a Bi2Te3\\ substrate has engendered a great deal of interest, in part due to stanene's predicted exotic properties. In particular, stanene shows promise in topological insulation, large-gap 2D quantum spin hall states, lossless electrical conduction, enhanced thermoelectricity, and topological superconductivity. However, atomistic investigations of growth mechanisms (needed to guide synthesis), phonon transport (crucial for designing thermoelectrics), and thermo-mechanical behavior of stanene are scarce. This paucity is primarily due to the lack of inter-atomic potentials that can accurately capture atomic interactions in stanene. To address this, we have developed a machine learnt bond-order potential (BOP) based on Tersoff's formalism that can accurately capture bond breaking/formation events, structure, energetics, thermodynamics, thermal conductivity, and mechanical properties of single layer tin, using a training set derived from density functional theory calculations. Finally, we employed our newly developed BOP to study anisotropy in thermal conductivity of stanene sheets, temperature induced rippling, as well as dependence of anharmonicity and thermal conductivity on temperature.

Large-area silicon sheet task

NASA Technical Reports Server (NTRS)

Morrison, A. D.

1982-01-01

A set of computer models was used to define a growth system configuration that was then built and used to grow web with lower thermally generated stress. Aspects of research in the edge-defined film-fed growth (EFG) method of making Si ribbon are reported. A technique was developed to determine base resistivity and carrier lifetime in semicrystalline wafers. Automated growth of 150 kg of 15 cm-dia ingot material per crucible is reviewed. Scanning transmisson electron microscopy (STEM) and microprobe investigations of processed EFG ribbon are reported. The chemical composition of the large precipitates was studied. The structural arrangement and the electrical activity of distentions or close to the central twin plane in processed material were studied. The electrical and structural properties of grain boundaries in silicon are discussed. Temperature-dependence measurements of zero-bias conductance, a photoconductivity technique, and deep-level transient spectroscopy (DLTS) were developed. A grooving and staining technique, secondary ion mass spectroscopy, and EBIC measurements in scanning electron microscopy were used to study enhanced diffusion of phosphorus at grain boundaries in polycrystaline silicon. The fundamental mechanisms of abrasion and wear and the deformation of Si by a diamond in various fluid environments are described. The efficiency of solar cells made from EFG ribbon and Semix Inc. material is reported.

Platelet-Derived Growth Factor-BB Stimulates Fibronectin Gene Expression in Fibroblasts Isolated from Rat Thoracic Aorta

DTIC Science & Technology

1994-06-13

MARYLAND 20814-4799 TEACHING HOSPITALS WALTER REED ARMY MEDtCA L CENTER APPROVAL SHEET NAVAL HOSPITAL. BETHESDA MALCOLM GROW AIR FORCE MEDICAL ...CENTER WILFORD HALL "IR FORCE MEDICAL CENTER Title of Dissertation: "Platelet-derived growth factor-BB stimulates fibronectin gene expression in...fascinating world of basic medical science. His dedication and pursuit of excellence in all facets of his work are standards by which I will guide my own

Avoidance of Phycomyces in a controlled environment.

PubMed Central

Meyer, P W; Matus, I J; Berg, H C

1987-01-01

The sporangiophore of the fungus Phycomyces bends away from nearby objects without ever touching them. It has been thought that these objects act as aerodynamic obstacles that damp random winds, thereby generating asymmetric distributions of a growth-promoting gas emitted by the growth zone. In the interest of testing this hypothesis, we studied avoidance in an environmental chamber in which convection was suppressed by a shallow thermal gradient. We also controlled pressure, temperature, and relative humidity of the air, electrostatic charge, and ambient light. A protocol was established that yielded avoidance rates constant from sporangiophore to sporangiophore to within +/- 10%. We found that avoidance occurred at normal rates in the complete absence of random winds. The rates were smaller at 100% than at lower values of relative humidity, but not by much. Remarkably, at a distance as great as 0.5 mm, avoidance from a 30-micron diam glass fiber (aligned parallel to the sporangiophore) was about the same as that from a planar glass sheet. However, the rate for the fiber fell more rapidly with distance. The rate for the sheet remained nearly constant out to approximately 4 mm. We conclude that avoidance depends either on adsorption by the barrier of a growth-inhibiting substance or emission by the barrier of a growth-promoting substance; it cannot occur by passive reflection. Models that can explain these effects are analyzed in the Appendix. PMID:3567313

Reconstructing the post-LGM decay of the Eurasian Ice Sheets with Ice Sheet Models; data-model comparison and focus on the Storfjorden (Svalbard) ice stream dynamics history

NASA Astrophysics Data System (ADS)

Petrini, Michele; Kirchner, Nina; Colleoni, Florence; Camerlenghi, Angelo; Rebesco, Michele; Lucchi, Renata G.; Forte, Emanuele; Colucci, Renato R.

2017-04-01

The challenge of reconstructing palaeo-ice sheets past growth and decay represent a critical task to better understand mechanisms of present and future global climate change. Last Glacial Maximum (LGM), and the subsequent deglaciation until Pre-Industrial time (PI) represent an excellent testing ground for numerical Ice Sheet Models (ISMs), due to the abundant data available that can be used in an ISM as boundary conditions, forcings or constraints to test the ISMs results. In our study, we simulate with ISMs the post-LGM decay of the Eurasian Ice Sheets, with a focus on the marine-based Svalbard-Barents Sea-Kara Sea Ice Sheet. In particular, we aim to reconstruct the Storfjorden ice stream dynamics history by comparing the model results with the marine geological data (MSGLs, GZWs, sediment cores analysis) available from the area, e.g., Pedrosa et al. 2011, Rebesco et al. 2011, 2013, Lucchi et al. 2013. Two hybrid SIA/SSA ISMs are employed, GRISLI, Ritz et al. 2001, and PSU, Pollard&DeConto 2012. These models differ mainly in the complexity with which grounding line migration is treated. Climate forcing is interpolated by means of climate indexes between LGM and PI climate. Regional climate indexes are constructed based on the non-accelerated deglaciation transient experiment carried out with CCSM3, Liu et al. 2009. Indexes representative of the climate evolution over Siberia, Svalbard and Scandinavia are employed. The impact of such refined representation as opposed to the common use of the NGRIP δ18O index for transient experiments is analysed. In this study, the ice-ocean interaction is crucial to reconstruct the Storfjorden ice stream dynamics history. To investigate the sensitivity of the ice shelf/stream retreat to ocean temperature, we allow for a space-time variation of basal melting under the ice shelves by testing two-equations implementations based on Martin et al. 2011 forced with simulated ocean temperature and salinity from the TraCE-21ka coupled climate simulation. In this presentation, we will show work in progress, address open issues, and sketch future work. In particular, we invite the community to suggest possibilities for model-data comparison and integration. Liu, Z., Otto-Bliesner, B.L., He, F., Brady, E.C., Tomas, R., Clark, P.U., Carlson, A.E., Lynch-Stieglitz, J., Curry, W., Brook, E. and Erickson, D., 2009. Transient simulation of last deglaciation with a new mechanism for Bólling-Alleród warming. Science, 325(5938), pp.310-314. Lucchi, R.G., Camerlenghi, A., Rebesco, M., Colmenero-Hidalgo, E., Sierro, F.J., Sagnotti, L., Urgeles, R., Melis, R., Morigi, C., Bárcena, M.A. and Giorgetti, G., 2013. Postglacial sedimentary processes on the Storfjorden and Kveithola trough mouth fans: Significance of extreme glacimarine sedimentation. Global and planetary change, 111, pp.309-326. Martin, M.A., Winkelmann, R., Haseloff, M., Albrecht, T., Bueler, E., Khroulev, C. and Levermann, A., 2011. The Potsdam Parallel Ice Sheet Model (PISM-PIK)-Part 2: Dynamic equilibrium simulation of the Antarctic ice sheet. The Cryosphere, 5(3), pp.727-740. Pedrosa, M.T., Camerlenghi, A., De Mol, B., Urgeles, R., Rebesco, M. and Lucchi, R.G., 2011. Seabed morphology and shallow sedimentary structure of the Storfjorden and Kveithola trough-mouth fans (north west Barents Sea). Marine Geology, 286(1), pp.65-81. Pollard, D. and DeConto, R.M., 2012. Description of a hybrid ice sheet-shelf model, and application to Antarctica. Geoscientific Model Development, 5(5), pp.1273-1295. Rebesco, M., Liu, Y., Camerlenghi, A., Winsborrow, M., Laberg, J.S., Caburlotto, A., Diviacco, P., Accettella, D., Sauli, C., Wardell, N. and Tomini, I., 2011. Deglaciation of the western margin of the Barents Sea Ice Sheet-a swath bathymetric and sub-bottom seismic study from the Kveithola Trough. Marine Geology, 279(1), pp.141-147. Rebesco, M., Laberg, J., Pedrosa, M., Camerlenghi, A., Lucchi, R., Zgur, F. and Wardell, N., 2013. Onset and growth of Trough-Mouth Fans on the North-Western Barents Sea margin e implications for the evolution of the Barents Sea/Svalbard Ice Sheet. Quaternary Science Reviews, 30, pp.1-8. Ritz, C., Rommelaere, V. and Dumas, C., 2001. Modeling the evolution of Antarctic ice sheet over the last 420,000 years: Implications for altitude changes in the Vostok region. Journal of Geophysical Research: Atmospheres, 106(D23), pp.31943-31964.

Large-scale synthesis of NbS2 nanosheets with controlled orientation on graphene by ambient pressure CVD.

PubMed

Ge, Wanyin; Kawahara, Kenji; Tsuji, Masaharu; Ago, Hiroki

2013-07-07

We report ambient pressure chemical vapor deposition (CVD) growth of single-crystalline NbS2 nanosheets with controlled orientation. On Si and SiO2 substrates, NbS2 nanosheets grow almost perpendicular to the substrate surface. However, when we apply transferred CVD graphene on SiO2 as a substrate, NbS2 sheets grow laterally lying on the graphene. The NbS2 sheets show the triangular and hexagonal shapes with a thickness of about 20-200 nm and several micrometres in the lateral dimension. Analyses based on X-ray diffraction and Raman spectroscopy indicate that the NbS2 nanosheets are single crystalline 3R-type with a rhombohedral structure of R3m space group. Our findings on the formation of highly aligned NbS2 nanosheets on graphene give new insight into the formation mechanism of NbS2 and would contribute to the templated growth of various layered materials.

Large area silicon sheet by EFG

NASA Technical Reports Server (NTRS)

1977-01-01

Some hypotheses to explain both of these features are advanced and the possible implications for solar cell performance are touched upon. The multiple ribbon growth system has shown a number of flaws with respect to the reliability of the basic furnace design. These definitely need to be rectified before any significant demonstration of multiple ribbon growth can proceed. The cartridges, however, have performed quite well. The work on 3" cartridge design and automatic controls has proceeded nearly on schedule and the report contains a detailed description of the approach and the equipment to be used for automatic control of ribbon growth.

ARARS Q's and A's: The fund-balancing waiver. Fact sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-01-01

The fact sheet implements the applicable or relevant and appropriate requirements (ARARs) provisions EPA has developed guidance and provided training to Regions and States on the identification of and compliance with ARARs. It is part of a series that provide guidance on a number of questions that arose in developing ARARs policies, in ARARs training sessions, and in identifying and complying with ARARs at specific sites. The fact sheet addresses the Fund-balancing waiver.

Fractal structure of low-temperature plasma of arc discharge as a consequence of the interaction of current sheets

NASA Astrophysics Data System (ADS)

Smolanov, N. A.

2016-01-01

The structure of the particles deposited from the plasma arc discharge were studied. The flow of plasma spreading from the cathode spot to the walls of the vacuum chamber. Electric and magnetic fields to influence the plasma flow. The fractal nature of the particles from the plasma identified by small-angle X-ray scattering. Possible cause of their formation is due to the instability of the growth front and nonequilibrium conditions for their production - a high speed transition of the vapor-liquid-solid or vapor - crystal. The hypothesis of a plasma arc containing dust particles current sheets was proposed.

Interhemispheric ice-sheet synchronicity during the last glacial maximum

USGS Publications Warehouse

Weber, Michael E.; Clark, Peter U.; Ricken, Werner; Mitrovica, Jerry X.; Hostetler, Steven W.; Kuhn, Gerhard

2011-01-01

The timing of the last maximum extent of the Antarctic ice sheets relative to those in the Northern Hemisphere remains poorly understood. We develop a chronology for the Weddell Sea sector of the East Antarctic Ice Sheet that, combined with ages from other Antarctic ice-sheet sectors, indicates that the advance to and retreat from their maximum extent was within dating uncertainties synchronous with most sectors of Northern Hemisphere ice sheets. Surface climate forcing of Antarctic mass balance would probably cause an opposite response, whereby a warming climate would increase accumulation but not surface melting. Our new data support teleconnections involving sea-level forcing from Northern Hemisphere ice sheets and changes in North Atlantic deep-water formation and attendant heat flux to Antarctic grounding lines to synchronize the hemispheric ice sheets.

Interhemispheric ice-sheet synchronicity during the Last Glacial Maximum.

PubMed

Weber, Michael E; Clark, Peter U; Ricken, Werner; Mitrovica, Jerry X; Hostetler, Steven W; Kuhn, Gerhard

2011-12-02

The timing of the last maximum extent of the Antarctic ice sheets relative to those in the Northern Hemisphere remains poorly understood. We develop a chronology for the Weddell Sea sector of the East Antarctic Ice Sheet that, combined with ages from other Antarctic ice-sheet sectors, indicates that the advance to and retreat from their maximum extent was within dating uncertainties synchronous with most sectors of Northern Hemisphere ice sheets. Surface climate forcing of Antarctic mass balance would probably cause an opposite response, whereby a warming climate would increase accumulation but not surface melting. Our new data support teleconnections involving sea-level forcing from Northern Hemisphere ice sheets and changes in North Atlantic deep-water formation and attendant heat flux to Antarctic grounding lines to synchronize the hemispheric ice sheets.

Geometric and kinematic analysis of structural elements along north front of Bagharan Kuh Mountain, NE Iran

NASA Astrophysics Data System (ADS)

Samimi, S.; Gholami, E.

2017-03-01

At the end of the western part of Bagharan Kuh Mountain in the northeast of Iran, mountain growth has been stopped toward the west because of the stress having been consumed by the thrusting movements and region rising instead of shear movement. Chahkand fault zone is situated at the western part of this mountain; this fault zone includes several thrust sheets that caused upper cretaceous ophiolite rocks up to younger units, peridotite exposure and fault related fold developing in the surface. In transverse perpendicular to the mountain toward the north, reduction in the parameters like faults dip, amount of deformation, peridotite outcrops show faults growth sequence and thrust sheets growth from mountain to plain, thus structural vergence is toward the northeast in this fault zone. Deformation in the east part of the region caused fault propagation fold with axial trend of WNW-ESE that is compatible with trending of fault plane. In the middle part, two types of folds is observed; in the first type, folding occurred before faulting and folds was cut by back thrust activity; in the second type, faults activity caused fault related folds with N60-90W axial trend. In order to hanging wall strain balance, back thrusts have been developed in the middle and western part which caused popup and fault bend folds with N20-70E trend. Back thrusts activity formed footwall synclines, micro folds, foliations, and uplift in this part of the region. Kinematic analysis of faults show stress axis σ1 = N201.6, 7, σ2 = N292.6, 7.1, σ3 = N64.8, 79.5; stress axis obtained by fold analysis confirm that minimum stress (σ3) is close to vertical so it is compatible with fault analysis. Based on the results, deformation in this region is controlled by compressional stress regime. This stress state is consistent with the direction of convergence between the Arabian and Eurasian plates. Also study of transposition, folded veins, different movements on the fault planes and back thrusts confirm the progressive deformation is dominant in this region that it increases from the east to the west.

Lightweight Structures

NASA Technical Reports Server (NTRS)

Whittenberger, J. Daniel

2001-01-01

Present structural concepts for hot static structures are conventional "sheet & stringer" or truss core construction. More weight-efficient concepts such as honeycomb and lattice block are being investigated, in combination with both conventional superalloys and TiAl. Development efforts for components made from TiAl sheet are centered on lower cost methods for sheet and foil production, plus alloy development for higher temperature capability. A low-cost casting technology recently developed for aluminum and steel lattice blocks has demonstrated the required higher strength and stiffness, with weight efficiency approach- ing honeycombs. The current effort is based on extending the temperature capability by developing lattice block materials made from IN-718 and Mar-M247.

Wrapping a liquid drop with a thin elastic sheet

NASA Astrophysics Data System (ADS)

Paulsen, Joseph; Démery, Vincent; Davidovitch, Benny; Santangelo, Chris; Russell, Thomas; Menon, Narayanan

2014-11-01

We study the wrapping of a liquid drop by an initially-planar ultrathin (~ 100 nm) circular sheet. These elastic sheets can completely relax compressive stresses by forming wrinkles. In the experiment, we find that when a small fraction of the drop is covered, the overall shape of the sheet (i.e. averaging over the wrinkles) is axisymmetric. As we shrink the drop further, the sheet develops radial folds that break the axisymmetry of the sheet and the drop. Our data are consistent with a model where the sheet selects the shape that minimizes the exposed liquid surface area. We thus identify a ``geometric wrapping'' regime, where the partially-wrapped shape depends only on the relative radii of the sheet and the drop; the global breaking of axisymmetry is independent of the elastic energy of the deformed sheet. This regime requires that bending energy is negligible compared to surface energy, in contrast to the ``capillary origami'' regime where the static shape of the drop comes from a balance of bending and capillary forces.

Environmental Education Activity Sheets 1-11.

ERIC Educational Resources Information Center

Halsey, Clifton F.; And Others

These activity sheets, developed by personnel of the Agricultural Extension Service of the University of Minnesota, were designed for youth group campers but may be used by other populations and individuals. Each activity sheet focuses on a separate topic: (1) Selecting Suitable Uses for Land, (2) Measuring the Steepness of Land, (3) Determining…

Disintegration of liquid sheets

NASA Technical Reports Server (NTRS)

Mansour, Adel; Chigier, Norman

1990-01-01

The development, stability, and disintegration of liquid sheets issuing from a two-dimensional air-assisted nozzle is studied. Detailed measurements of mean drop size and velocity are made using a phase Doppler particle analyzer. Without air flow the liquid sheet converges toward the axis as a result of surface tension forces. With airflow a quasi-two-dimensional expanding spray is formed. The air flow causes small variations in sheet thickness to develop into major disturbances with the result that disruption starts before the formation of the main break-up region. In the two-dimensional variable geometry air-blast atomizer, it is shown that the air flow is responsible for the formation of large, ordered, and small chaotic 'cell' structures.

Overload and Underload Effects on the Fatigue Crack Growth Behavior of the 2024-T3 Aluminum Alloy

NASA Technical Reports Server (NTRS)

Dawicke, David S.

1997-01-01

Fatigue crack growth tests were conducted on 0.09 inch thick, 3.0 inch wide middle-crack tension specimens cut from sheets of 2024-T3 aluminum alloy. The tests were conducted using a load sequence that consisted of a single block of 2,500 cycles of constant amplitude loading followed by an overload/underload combination. The largest fatigue crack growth life occurred for the tests with the overload stress equal to 2 times the constant amplitude stress and the underload stress equal to the constant amplitude minimum stress. For the tests with compressive underloads, the fatigue crack growth life decreased with increasing compressive underload stress.

Combined Use of Mesenchymal Stromal Cell Sheet Transplantation and Local Injection of SDF-1 for Bone Repair in a Rat Nonunion Model.

PubMed

Chen, Guangnan; Fang, Tingting; Qi, Yiying; Yin, Xiaofan; Di, Tuoyu; Feng, Gang; Lei, Zhong; Zhang, Yuxiang; Huang, Zhongming

2016-10-01

Bone nonunion treatments pose a challenge in orthopedics. This study investigated the joint effects of using mesenchymal stem cell (MSC) sheets with local injection of stromal cell-derived factor-1 (SDF-1) on bone formation. In vitro, we found that migration of MSCs was mediated by SDF-1 in a dose-dependent manner. Moreover, stimulation with SDF-1 had no direct effect on the proliferation or osteogenic differentiation of MSCs. Furthermore, the results indicated elevated expression levels of bone morphogenetic protein 2, alkaline phosphatase, osteocalcin, and vascular endothelial growth factor in MSC sheets compared with MSCs cultured in medium. New bone formation in fractures was evaluated by X-ray, micro-computed tomography (micro-CT), hematoxylin and eosin (H&E) staining, Safranin-O staining, and immunohistochemistry in vivo. In the rat bone fracture model, the MSC sheets transplanted into the injured site along with injection of SDF-1 showed significantly more new bone formation within the gap. Moreover, at 8 weeks, complete bone union was obtained in this group. In contrast, the control group showed nonunion of the bone. Our study suggests a new strategy involving the use of MSC sheets with a local injection of SDF-1 for hard tissue reconstruction, such as the healing of nonunions and bone defects.

Instability of current sheets with a localized accumulation of magnetic flux

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pritchett, P. L.

2015-06-15

The longstanding problem of whether a current sheet with curved magnetic field lines associated with a small “normal” B{sub z} component is stable is investigated using two-dimensional electromagnetic particle-in-cell simulations, employing closed boundary conditions analogous to those normally assumed in energy principle calculations. Energy principle arguments [Sitnov and Schindler, Geophys. Res. Lett. 37, L08102 (2010)] have suggested that an accumulation of magnetic flux at the tailward end of a thin current sheet could produce a tearing instability. Two classes of such current sheet configurations are probed: one with a monotonically increasing B{sub z} profile and the other with a localizedmore » B{sub z} “hump.” The former is found to be stable (in 2D) over any reasonable time scale, while the latter is prone to an ideal-like instability that shifts the hump peak in the direction of the curvature normal and erodes the field on the opposite side. The growth rate of this instability is smaller by an order of magnitude than previous suggestions of an instability in an open system. An example is given that suggests that such an unstable hump configuration is unlikely to be produced by external driving of a current sheet with no B{sub z} accumulation even in the presence of open boundary conditions.« less

Experimental investigation of the stability of a moving radial liquid sheet

NASA Astrophysics Data System (ADS)

Paramati, Manjula; Tirumkudulu, Mahesh

2013-11-01

Experiments were conducted to understand the stability of moving radial liquid sheets formed by the head-on impingement of two co-linear water jets using laser induced fluorescence technique (LIF). Acoustic sinusoidal fluctuations were introduced at the jet impingement point and we measured the displacement of the center line of the liquid sheet (sinuous mode) and the thickness variation (varicose mode) of the disturbed liquid sheet. Our experiments show that the sinuous disturbances grow as they are convected outward in the radial direction even in the smooth regime (We < 800). In the absence of the acoustic forcing, the measured thickness has the expected 1/r dependence. Interestingly, we were unable to detect any thickness variation about the pre-stimulus values in the presence of acoustic forcing suggesting that the variation in the thickness is lower than the resolution of the technique (+/- 1 μm). The growth rates of the sinuous mode determined from the wave envelope matches with the prediction of a recent theory by Tirumkudulu and Paramati (Communicated to Phys. Of Fluids, 2013) which accounts for the inertia of the liquid phase and the surface tension force in a radial liquid sheet while neglecting the inertial effects due to the surrounding gas phase. The authors acknowledge the financial assistance from Indo-French Center for Pro- motion of Advanced Research and also Indian institute of technology Bombay.

Sectional Finite Element Analysis on Viscous Pressure Forming of Sheet Metal

NASA Astrophysics Data System (ADS)

Liu, Jianguang; Wang, Zhongjin; Liu, Yan

2007-05-01

Viscous pressure forming (VPF) is a recently developed sheet flexible-die forming process, which uses a kind of semi-solid, flowable and viscous material as pressure-carrying medium that typically applied on one side of the sheet metal or on both sides of sheet metal. Different from traditional sheet metal forming processes in which sheet metal is the unique deformation-body, VPF is a coupling process of visco-elastoplastic bulk deformation of viscous medium and elasto-plastic deformation of sheet metal. A sectional finite element model for the coupled deformation between visco-elastoplastic body and elasto-plastic sheet metal was proposed to analyze VPF. The resolution of the Updated Lagrangian formulation is based on a static approach. By using static-explicit time integration strategy, the deformation of elasto-plastic sheet metal and visco-elastoplastic body can keep stable. The frictional contact between sheet metal and visco-elastoplastic body is treated by penalty function method. Using the proposed algorithm, sheet metal viscous pressure bulging (VPB) process is analyzed and compared with experiments. A good agreement between numerical simulation results and experimental ones proved the efficiency and stability of this algorithm.

On the instability of a liquid sheet moving in vacuum

NASA Astrophysics Data System (ADS)

Sisoev, G. M.; Osiptsov, A. N.; Koroteev, A. A.

2018-03-01

A linear stability analysis of a non-isothermal liquid sheet moving in vacuum is studied taking into account the temperature dependencies of the liquid viscosity, thermal conductivity, and surface tension coefficients. It is found that there are two mechanisms of instability. The short-wave instability is caused by viscosity stratification across the sheet due to nonuniform temperature profiles developed downstream in the cooling sheet. The long-wave thermocapillary instability is caused by the temperature gradient along the sheet surfaces. Computed examples of steady flows and their instabilities demonstrated that the unstable short waves have much larger amplification factors.

Process development for Ni-Cr-ThO2 and Ni-Cr-Al-ThO2 sheet

NASA Technical Reports Server (NTRS)

Cook, R. C.; Norris, L. F.

1973-01-01

A process was developed for the production of thin gauge Ni-Cr-ThO2 sheet. The process was based on the elevated temperature deposition of chromium onto a wrought Ni-2%ThO2 sheet and subsequent high temperature diffusion heat treatments to minimize chromium concentration gradients within the sheet. The mechanical properties of the alloy were found to be critically dependent on those of the Ni-2%ThO2 sheet. A similar process for the production of a Ni-Cr-Al-ThO2 alloy having improved oxidation resistance was investigated but the non-reproducible deposition of aluminum from duplex Cr/Al packs precluded successful scale-up. The mechanical properties of the Ni-Cr-Al-ThO2 alloys were generally equivalent to the best Ni-Cr-ThO2 alloy produced in the programme.

Environmental Detection of Single-Walled Carbon Nanotubes Utilizing Near-Infrared Fluorescence

EPA Science Inventory

There are a growing number of applications for carbon nanotubes (CNT) in modern technologies and, subsequently, growth in production of CNT has expanded rapidly. Single-walled CNT (SWCNT) consist of a graphene sheet rolled up into a tube. With growing manufacture and use, the ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fact sheet describing the National Renewable Energy Laboratory's (NREL's) Fuel Cell Technology Status Analysis Project. NREL is seeking fuel cell industry partners from the United States and abroad to participate in an objective and credible analysis of commercially available fuel cell products to benchmark the current state of the technology and support industry growth.

Comparison of the canine corneal epithelial cell sheets cultivated from limbal stem cells on canine amniotic membrane, atelocollagen gel, and temperature-responsive culture dish.

PubMed

Nam, Eunryel; Fujita, Naoki; Morita, Maresuke; Tsuzuki, Keiko; Lin, Hsing Yi; Chung, Cheng Shu; Nakagawa, Takayuki; Nishimura, Ryohei

2015-07-01

The current study compared canine corneal epithelial cell sheets cultivated from limbal stem cells on amniotic membrane, atelocollagen gel, and temperature-responsive culture dish. We collected limbal epithelial cells from the intact eyes of beagles and cultivated the cells on denuded canine amniotic membranes, temperature-responsive cell culture labware, and collagen gel with 3T3 feeder cells. Immunofluorescence staining for Ki-67 was used to analyze the capacity of cell proliferation in the sheets. Immunofluorescence staining was also performed for the corneal epithelium-specific marker cytokeratin 3 and putative stem cell markers ABCG2 and p63. Reverse-transcription polymerase chain reaction (RT-PCR) was performed to detect ABCG2 and p63. The growth rates of the cultivated cells, or the times it took them to reach confluency, were different for the three scaffolds. The cultivated sheet on the temperature-responsive dish consisted of 2-3 layers, while those on the collagen gel and on the amniotic membrane consisted of 5-8 layers. The basal layer cells grown on all three scaffolds expressed putative stem cell markers. In real-time RT-PCR analysis, the highest level of p63 was observed in the sheets grown on collagen gel. In this study, the cells cultured on the collagen gel demonstrated a capacity for cell proliferation, and the expressions of stem cells in the sheets suggested that collagen gel is the most suitable carrier for clinical use. © 2014 American College of Veterinary Ophthalmologists.

Electron Cooling and Isotropization during Magnetotail Current Sheet Thinning: Implications for Parallel Electric Fields

NASA Astrophysics Data System (ADS)

Lu, San; Artemyev, A. V.; Angelopoulos, V.

2017-11-01

Magnetotail current sheet thinning is a distinctive feature of substorm growth phase, during which magnetic energy is stored in the magnetospheric lobes. Investigation of charged particle dynamics in such thinning current sheets is believed to be important for understanding the substorm energy storage and the current sheet destabilization responsible for substorm expansion phase onset. We use Time History of Events and Macroscale Interactions during Substorms (THEMIS) B and C observations in 2008 and 2009 at 18 - 25 RE to show that during magnetotail current sheet thinning, the electron temperature decreases (cooling), and the parallel temperature decreases faster than the perpendicular temperature, leading to a decrease of the initially strong electron temperature anisotropy (isotropization). This isotropization cannot be explained by pure adiabatic cooling or by pitch angle scattering. We use test particle simulations to explore the mechanism responsible for the cooling and isotropization. We find that during the thinning, a fast decrease of a parallel electric field (directed toward the Earth) can speed up the electron parallel cooling, causing it to exceed the rate of perpendicular cooling, and thus lead to isotropization, consistent with observation. If the parallel electric field is too small or does not change fast enough, the electron parallel cooling is slower than the perpendicular cooling, so the parallel electron anisotropy grows, contrary to observation. The same isotropization can also be accomplished by an increasing parallel electric field directed toward the equatorial plane. Our study reveals the existence of a large-scale parallel electric field, which plays an important role in magnetotail particle dynamics during the current sheet thinning process.

A transient fully coupled climate-ice-sheet simulation of the last glacial inception

NASA Astrophysics Data System (ADS)

Lofverstrom, M.; Otto-Bliesner, B. L.; Lipscomb, W. H.; Fyke, J. G.; Marshall, S.; Sacks, B.; Brady, E. C.

2017-12-01

The last glacial inception occurred around 115 ka, following a relative minimum in the Northern Hemisphere summer insolation. It is believed that small and spatially separated ice caps initially formed in the high elevation regions of northern Canada, Scandinavia, and along the Siberian Arctic coast. These ice caps subsequently migrated down in the valleys where they coalesced and formed the initial seeds of the large coherent ice masses that covered the northern parts of the North American and Eurasian continents over most of the last glacial cycle. Sea level records show that the initial growth period lasted for about 10 kyrs, and the resulting ice sheets may have lowered the global sea level by as much as 30 to 50 meters. Here we examine the transient climate system evolution over the period between 118 and 110 ka, using the fully coupled Community Earth System Model, version 2 (CESM2). This model features a two-way coupled high-resolution (4x4 km) ice-sheet component (Community Ice Sheet model, version 2; CISM2) that simulates ice sheets as an interactive component of the climate system. We impose a transient forcing protocol where the greenhouse gas concentrations and the orbital parameters follow the nominal year in the simulation; the model topography is also dynamically evolving in order to reflect changes in ice elevation throughout the simulation. The analysis focuses on how the climate system evolves over this time interval, with a special focus on glacial inception in the high-latitude continents. Results will highlight how the evolving ice sheets compare to data and previous model based reconstructions.

Century/millennium internal climate oscillations in an ocean-atmosphere-continental ice sheet model

NASA Technical Reports Server (NTRS)

Birchfield, Edward G.; Wang, Huaxiao; Rich, Jonathan J.

1994-01-01

We demonstrate in a simple climate model that there exist nonlinear feedbacks between the atmosphere, ocean, and ice sheets capable of producing century/millennium timescale internal oscillations resembling those seen in the paleoclimate record. Feedbacks involve meridional heat and salt transports in the North Atlantic, surface ocean freshwater fluxes associated with melting and growing continental ice sheets in the northen hemisphere and with Atlantic to Pacific water vapor transport. The positive feedback between the production of North Atlantic Deep Water (NADW) and the meridional salt transport by the Atlantic thermohaline circulation tends to destabilize the climate system, while the negative feedback between the freshwater flux, either to or from the continental ice sheets, and meridional heat flux to the high-latitude North Atlantic, accomplished by the thermohaline circulation, stabilizes the system. The thermohaline circulation plays a central role in both positive and negative feedbacks because of its transport of both heat and salt. Because of asymmetries between the growth and melt phases the oscillations are, in general, accompanied by a growing or decreasing ice volume over each cycle, which in the model is reflected by increasing or decreasing mean salinity.

Enabling Colloidal Synthesis of Edge-Oriented MoS2 with Expanded Interlayer Spacing for Enhanced HER Catalysis.

PubMed

Sun, Yugang; Alimohammadi, Farbod; Zhang, Dongtang; Guo, Guangsheng

2017-03-08

By selectively promoting heterogeneous nucleation/growth of MoS 2 on graphene monolayer sheets, edge-oriented (EO) MoS 2 nanosheets with expanded interlayer spacing (∼9.4 Å) supported on reduced graphene oxide (rGO) sheets were successfully synthesized through colloidal chemistry, showing the promise in low-cost and large-scale production. The number and edge length of MoS 2 nanosheets per area of graphene sheets were tuned by controlling the reaction time in the microwave-assisted solvothermal reduction of ammonium tetrathiomolybdate [(NH 4 ) 2 MoS 4 ] in dimethylformamide. The edge-oriented and interlayer-expanded (EO&IE) MoS 2 /rGO exhibited significantly improved catalytic activity toward hydrogen evolution reaction (HER) in terms of larger current density, lower Tafel slope, and lower charge transfer resistance compared to the corresponding interlayer-expanded MoS 2 sheets without edge-oriented geometry, highlighting the importance of synergistic effect between edge-oriented geometry and interlayer expansion on determining HER activity of MoS 2 nanosheets. Quantitative analysis clearly shows the linear dependence of current density on the edge length of MoS 2 nanosheets.

Prevention of hypertrophic scars and keloids by the prophylactic use of topical silicone gel sheets following a surgical procedure in an office setting.

PubMed

Gold, M H; Foster, T D; Adair, M A; Burlison, K; Lewis, T

2001-07-01

Topical silicone gel sheeting has been used for more than 20 years to help reduce the size of hypertrophic scars and keloids. Its clinical efficacy and safety is well established. To determine whether topical silicone gel sheeting can be used to prevent hypertrophic scars and keloids from forming following dermatologic skin surgery. Patients undergoing skin surgery were stratified into two groups: those with no history of abnormal scarring (low-risk group) and those with a history of abnormal scarring (high-risk group). Following the procedure, patients within each group were randomized to receive either routine postoperative care or topical silicone gel sheeting (48 hours after surgery). Patients were followed for 6 months. In the low-risk group, there were no statistical differences between individuals using routine postoperative care or using topical silicone gel sheets. In the high-risk group, there was a statistical difference (39% versus 71%) between patients who did not develop abnormal scars and used topical silicone gel sheeting and patients who developed abnormal scars after routine postoperative treatment. Those individuals having a scar revision procedure also showed a statistical difference if topical silicone gel sheeting was used following surgery. Topical silicone gel sheeting, with a 20-year history of satisfaction in dermatology, now appears to be useful in the prevention of hypertrophic scars and keloids in patients undergoing scar revision.

The East Antarctic Ice Sheet and the Gamburtsev Subglacial Mountains (Invited)

NASA Astrophysics Data System (ADS)

Bell, R. E.; Studinger, M.; Ferraccioli, F.; Damaske, D.; Finn, C.; Braaten, D. A.; Fahnestock, M. A.; Jordan, T. A.; Corr, H.; Elieff, S.; Frearson, N.; Block, A. E.; Rose, K.

2009-12-01

Models of the onset of glaciation in Antarctica routinely document the early growth of the ice sheet on the summit of the Gamburtsev Subglacial Mountains in the center of the East Antarctic Craton. While ice sheet models replicate the formation of the East Antarctic ice sheet 35 million years ago, the age, evolution and structure of the Gamburtsev Mountains remain completely unresolved. During the International Polar Year scientists from seven nations have launched a major collaborative program (AGAP) to explore the Gamburtsev Subglacial Mountains buried by the East Antarctic ice sheet and bounded by numerous subglacial lakes. The AGAP umbrella is a multi-national, multi-disciplinary effort and includes aerogeophysics, passive seismology, traverse programs and will be complimented by future ice core and bedrock drilling. A major new airborne data set including gravity; magnetics; ice thickness; SAR images of the ice-bed interface; near-surface and deep internal layers; and ice surface elevation is providing insights into a more dynamic East Antarctica. More than 120,000 km of aerogeophysical data have been acquired from two remote field camps during the 2008/09 field season. AGAP effort was designed to address several fundamental questions including: 1) What role does topography play in the nucleation of continental ice sheets? 2) How do tectonic processes control the formation, distribution, and stability of subglacial lakes? The preliminary analysis of this major new data set indicated these 3000m high mountains are deeply dissected by a dendritic system. The northern margin of the mountain range terminates against the inland extent of the Lambert Graben. Evidence of the onset of glaciation is preserved as cirques and U shaped valleys along the axis of the uplifted massifs. The geomorphology reflects the interaction between the ice sheet and the Gamburtsev Mountains. Bright reflectors in the radar data in the deep valleys indicate the presence of water that has the potential to influence ice sheet flow. Crevassing and disrupted internal layers are present in the deep ice found in the inland extent of the Lambert Graben. Preliminary analysis indicates both a more dynamic East Antarctic ice sheet and a more complex tectonic evolution for East Antarctica.

Caledonian evolution of the Moine Supergroup: Prograde garnet growth and context for quartz fabric-based deformation thermometry

NASA Astrophysics Data System (ADS)

Law, Richard; Ashley, Kyle; Thigpen, Ryan

2014-05-01

Despite the detailed Caledonian structural/tectonic framework developed for the Moine Supergroup of northern Scotland, debate continues over the tectonic processes that drove metamorphism. Rapid temporal evolution of the metamorphic sequence has led some geologists to suggest that crustal thickening alone cannot provide sufficient heat flow to reach the metamorphic grades observed. Rather, they postulate that large-scale contact metamorphism or initial heating in an extensional, back-arc setting is required. We present coupled petrographic analyses and forward phase stability modeling for quantifying prograde metamorphic evolution in pelite horizons dispersed across the Caledonian thrust sheets. Results suggest garnet growth was syn-kinematic during prograde decompression. Rutile and ilmenite inclusions in garnet cores and rims, respectively, support this claim, while chemical profiles and crystal morphology argue against a detrital origin for these garnet grains. The observed clockwise P-T path for these garnets is incompatible with extensional or contact metamorphic models (would require counter-clockwise paths). Rather, the P-T data suggests advection of isotherms during thrusting as the dominant mechanism for metamorphism (Thigpen et al., 2013). Recent studies in other orogens (e.g., Spear et al., 2012) suggest that heating over long time scales under mid-crustal conditions may not be needed to reach the metamorphic grades observed. Therefore the structurally higher, more hinterland Caledonian thrust sheets may have reached peak metamorphism in a much shorter time period than previously expected. The paucity of pelitic horizons across the foreland-positioned Moine thrust sheet has previously limited insight into the prograde evolution of these rocks. However, the dominance of quartz-rich units has allowed the thermal structure of the thrust sheet to be evaluated using quartz c-axis fabric opening angle-based deformation thermometry. Microstructures in the pelites sampled indicate that garnet (rim) growth is syn-kinematic with respect to the Scandian (mid-Silurian) deformation fabrics. Deformation temperatures indicated by quartz fabric opening angles are very similar to temperatures of metamorphism constrained using pseudosection and petrographic data from adjacent pelite horizons. This suggests that the deformation- and petrology-based data sets are providing information on the same thermal event. These results support the use of quartz deformation thermometry in obtaining thermal profiles across tectonic units where rock types (usually pelites), with metamorphic mineral assemblages suitable for petrology-based thermometry, are not present. Thigpen, J.R., Law, R.D., Loehn, C.L., Strachan, R.A., Tracy, R.J., Lloyd, G.E., Roth, B.L., and Brown, S.J., 2013, Thermal structure and tectonic evolution of the Scandian orogenic wedge, Scottish Caledonides: integrating geothermometry, deformation temperatures and conceptual kinematic-thermal models, J. Metamorphic Geol., 31, 813-842. Spear, F.S., Ashley, K.T., Webb, L.E., and Thomas, J.B., 2012, Ti diffusion in quartz inclusions: implications for metamorphic time scales, Contrib. Mineral Petrol., 164, 977-986.

Sheet Metal Contract. Project Report Phase I with Research Findings.

ERIC Educational Resources Information Center

Kirkpatrick, Thomas; Sappe', Hoyt

This report provides results of Phase I of a project that researched the occupational area of sheet metal, established appropriate committees, and conducted task verification. These results are intended to guide development of a program designed to train sheet metal workers. Section 1 contains general information: purpose of Phase I; description…

Introduction to Production/Manufacturing Drafting. Drafting Module 8. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This module, 1 of 10 in the Drafting curriculum guide developed in Missouri, contains 3 units of study that include some or all of the following components: performance objectives, lesson plans, information sheets, transparency masters, handouts, assignment sheets, job sheets, a unit test, and answers to the unit test. Special instructions on…

Financing Home Energy and Renewable Energy Improvements with FHA PowerSaver Loans (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2014-07-01

This fact sheet is a revision to the PowerSaver Loan Benefits fact sheet from April 2014. It describes how the U.S. Department of Housing and Urban Development (HUD) PowerSaver Loan Program offers borrowers low-cost FHA-insured loans to make energy-saving improvements to their homes.

Engineering tubular bone using mesenchymal stem cell sheets and coral particles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geng, Wenxin; Ma, Dongyang; Yan, Xingrong

Highlights: • We developed a novel engineering strategy to solve the limitations of bone grafts. • We fabricated tubular constructs using cell sheets and coral particles. • The composite constructs showed high radiological density and compressive strength. • These characteristics were similar to those of native bone. -- Abstract: The development of bone tissue engineering has provided new solutions for bone defects. However, the cell-scaffold-based approaches currently in use have several limitations, including low cell seeding rates and poor bone formation capacity. In the present study, we developed a novel strategy to engineer bone grafts using mesenchymal stem cell sheetsmore » and coral particles. Rabbit bone marrow mesenchymal stem cells were continuously cultured to form a cell sheet with osteogenic potential and coral particles were integrated into the sheet. The composite sheet was then wrapped around a cylindrical mandrel to fabricate a tubular construct. The resultant tubular construct was cultured in a spinner-flask bioreactor and subsequently implanted into a subcutaneous pocket in a nude mouse for assessment of its histological characteristics, radiological density and mechanical property. A similar construct assembled from a cell sheet alone acted as a control. In vitro observations demonstrated that the composite construct maintained its tubular shape, and exhibited higher radiological density, compressive strength and greater extracellular matrix deposition than did the control construct. In vivo experiments further revealed that new bone formed ectopically on the composite constructs, so that the 8-week explants of the composite sheets displayed radiological density similar to that of native bone. These results indicate that the strategy of using a combination of a cell sheet and coral particles has great potential for bone tissue engineering and repairing bone defects.« less

Cell delivery in regenerative medicine: the cell sheet engineering approach.

PubMed

Yang, Joseph; Yamato, Masayuki; Nishida, Kohji; Ohki, Takeshi; Kanzaki, Masato; Sekine, Hidekazu; Shimizu, Tatsuya; Okano, Teruo

2006-11-28

Recently, cell-based therapies have developed as a foundation for regenerative medicine. General approaches for cell delivery have thus far involved the use of direct injection of single cell suspensions into the target tissues. Additionally, tissue engineering with the general paradigm of seeding cells into biodegradable scaffolds has also evolved as a method for the reconstruction of various tissues and organs. With success in clinical trials, regenerative therapies using these approaches have therefore garnered significant interest and attention. As a novel alternative, we have developed cell sheet engineering using temperature-responsive culture dishes, which allows for the non-invasive harvest of cultured cells as intact sheets along with their deposited extracellular matrix. Using this approach, cell sheets can be directly transplanted to host tissues without the use of scaffolding or carrier materials, or used to create in vitro tissue constructs via the layering of individual cell sheets. In addition to simple transplantation, cell sheet engineered constructs have also been applied for alternative therapies such as endoscopic transplantation, combinatorial tissue reconstruction, and polysurgery to overcome limitations of regenerative therapies and cell delivery using conventional approaches.

Optimization of CO2 laser cutting parameters on Austenitic type Stainless steel sheet

NASA Astrophysics Data System (ADS)

Parthiban, A.; Sathish, S.; Chandrasekaran, M.; Ravikumar, R.

2017-03-01

Thin AISI 316L stainless steel sheet widely used in sheet metal processing industries for specific applications. CO2 laser cutting is one of the most popular sheet metal cutting processes for cutting of sheets in different profile. In present work various cutting parameters such as laser power (2000 watts-4000 watts), cutting speed (3500mm/min - 5500 mm/min) and assist gas pressure (0.7 Mpa-0.9Mpa) for cutting of AISI 316L 2mm thickness stainless sheet. This experimentation was conducted based on Box-Behenken design. The aim of this work is to develop a mathematical model kerf width for straight and curved profile through response surface methodology. The developed mathematical models for straight and curved profile have been compared. The Quadratic models have the best agreement with experimental data, and also the shape of the profile a substantial role in achieving to minimize the kerf width. Finally the numerical optimization technique has been used to find out best optimum laser cutting parameter for both straight and curved profile cut.

New directions in the science and technology of advanced sheet explosive formulations and the key energetic materials used in the processing of sheet explosives: Emerging trends.

PubMed

Talawar, M B; Jangid, S K; Nath, T; Sinha, R K; Asthana, S N

2015-12-30

This review presents the work carried out by the international community in the area of sheet explosive formulations and its applications in various systems. The sheet explosive is also named as PBXs and is a composite material in which solid explosive particles like RDX, HMX or PETN are dispersed in a polymeric matrix, forms a flexible material that can be rolled/cut into sheet form which can be applied to any complex contour. The designed sheet explosive must possess characteristic properties such as flexible, cuttable, water proof, easily initiable, and safe handling. The sheet explosives are being used for protecting tanks (ERA), light combat vehicle and futuristic infantry carrier vehicle from different attacking war heads etc. Besides, sheet explosives find wide applications in demolition of bridges, ships, cutting and metal cladding. This review also covers the aspects such as risks and hazard analysis during the processing of sheet explosive formulations, effect of ageing on sheet explosives, detection and analysis of sheet explosive ingredients and the R&D efforts of Indian researchers in the development of sheet explosive formulations. To the best of our knowledge, there has been no review article published in the literature in the area of sheet explosives. Copyright © 2015 Elsevier B.V. All rights reserved.

Low Cost Manufacturing Approach of High Temperature PMC Components

NASA Technical Reports Server (NTRS)

Kannmacher, Kevin

1997-01-01

The overall objective is to develop a satisfactory sheet molding compound (SMC) of a high temperature polyimide, such as PMR-11-50, VCAP-75, or NB2-76, and to develop compression molding processing parameters for a random, chopped fiber, high temperature, sheet molding compound that will be more affordable than the traditional hand lay-up fabrication methods. Compression molding will reduce manufacturing costs of composites by: (1) minimizing the conventional machining required after fabrication due to the use of full 360 deg matched tooling, (2) reducing fabrication time by minimizing the intensive hand lay-up operations associated with individual ply fabrication techniques, such as ply orientation and ply count and (3) possibly reducing component mold time by advanced B-staging prior to molding. This program is an integral part of Allison's T406/AE engine family's growth plan, which will utilize technologies developed under NASA's Sub-sonic Transport (AST) programs, UHPTET initiatives, and internally through Allison's IR&D projects. Allison is aggressively pursuing this next generation of engines, with both commercial and military applications, by reducing the overall weight of the engine through the incorporation of advanced, lightweight, high temperature materials, such as polymer matrix composites. This infusion of new materials into the engine is also a major factor in reducing engine cost because it permits the use of physically smaller structural components to achieve the same thrust levels as the generation that it replaced. A lighter, more efficient propulsion system translates to a substantial cost and weight savings to an airframe's structure.

The Svalbard-Barents Sea ice-sheet - Historical, current and future perspectives

NASA Astrophysics Data System (ADS)

Ingólfsson, Ólafur; Landvik, Jon Y.

2013-03-01

The history of research on the Late Quaternary Svalbard-Barents Sea ice sheet mirrors the developments of ideas and the shifts of paradigms in glacial theory over the past 150 years. Since the onset of scientific research there in the early 19th Century, Svalbard has been a natural laboratory where ideas and concepts have been tested, and played an important (but rarely acknowledged) role in the break-through of the Ice Age theory in the 1870's. The history of how the scientific perception of the Svalbard-Barents sea ice sheet developed in the mid-20th Century also tells a story of how a combination of fairly scattered and often contradictory observational data, and through both deductive and inductive reasoning, could outline a major ice sheet that had left but few tangible fingerprints. Since the 1980's, with increased terrestrial stratigraphical data, ever more marine geological evidence and better chronological control of glacial events, our perception of the Svalbard-Barents Sea ice sheet has changed. The first reconstructions depicted it as a static, concentric, single-domed ice sheet, with ice flowing from an ice divide over the central northern Barents Sea that expanded and declined in response to large-scale, Late Quaternary climate fluctuations, and which was more or less in tune with other major Northern Hemisphere ice sheets. We now increasingly perceive it as a very dynamic, multidomed ice sheet, controlled by climate fluctuations, relative sea-level change, as well as subglacial topography, substrate properties and basal temperature. In this respect, the Svalbard-Barents Sea ice sheet will increasingly hold the key for understanding the dynamics and processes of how marine-based ice sheets build-up and decay.

Widespread Refreezing of Both Surface and Basal Melt Water Beneath the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Bell, R. E.; Tinto, K. J.; Das, I.; Wolovick, M.; Chu, W.; Creyts, T. T.; Frearson, N.

2013-12-01

The isotopically and chemically distinct, bubble-free ice observed along the Greenland Ice Sheet margin both in the Russell Glacier and north of Jacobshavn must have formed when water froze from subglacial networks. Where this refreezing occurs and what impact it has on ice sheet processes remain unclear. We use airborne radar data to demonstrate that freeze-on to the ice sheet base and associated deformation produce large ice units up to 700 m thick throughout northern Greenland. Along the ice sheet margin, in the ablation zone, surface meltwater, delivered via moulins, refreezes to the ice sheet base over rugged topography. In the interior, water melted from the ice sheet base is refrozen and surrounded by folded ice. A significant fraction of the ice sheet is modified by basal freeze-on and associated deformation. For the Eqip and Petermann catchments, representing the ice sheet margin and interior respectively, extensive airborne radar datasets show that 10%-13% of the base of the ice sheet and up to a third of the catchment width is modified by basal freeze-on. The interior units develop over relatively subdued topography with modest water flux from basal melt where conductive cooling likely dominates. Steps in the bed topography associated with subglacial valley networks may foster glaciohydraulic supercooling. The ablation zone units develop where both surface melt and crevassing are widespread and large volumes of surface meltwater will reach the base of the ice sheet. The relatively steep topography at the upslope edge of the ablation zone units combined with the larger water flux suggests that supercooling plays a greater role in their formation. The ice qualities of the ablation zone units should reflect the relatively fresh surface melt whereas the chemistry of the interior units should reflect solute-rich basal melt. Changes in basal conditions such as the presence of till patches may contribute to the formation of the large basal units near the Northeast Ice Stream. The contrasting rheology of glacial and interglacial ice may also enhance the deformation associated with freeze-on beneath large ice sheets. The occurrence of basal units both in the ice sheet interior and in the thermally very different ablation zone indicates refreezing is widespread and can occur in many environments beneath an ice sheet. This process appears to influence the morphology and behavior of the ice sheet from top to bottom.